ORF_ID e_value Gene_name EC_number CAZy COGs Description
DEBBBBON_00006 5.5e-139 mreC M Involved in formation and maintenance of cell shape
DEBBBBON_00007 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DEBBBBON_00008 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
DEBBBBON_00009 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEBBBBON_00010 2.9e-218 araT 2.6.1.1 E Aminotransferase
DEBBBBON_00011 7e-144 recO L Involved in DNA repair and RecF pathway recombination
DEBBBBON_00012 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DEBBBBON_00013 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEBBBBON_00014 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DEBBBBON_00015 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DEBBBBON_00016 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DEBBBBON_00017 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DEBBBBON_00018 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DEBBBBON_00019 1.1e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DEBBBBON_00020 1e-90 L transposase activity
DEBBBBON_00021 3.5e-50 L transposition
DEBBBBON_00022 2e-32 L Integrase core domain protein
DEBBBBON_00023 2.3e-161 S CHAP domain
DEBBBBON_00024 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
DEBBBBON_00025 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DEBBBBON_00026 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DEBBBBON_00027 1.2e-137 1.1.1.169 H Ketopantoate reductase
DEBBBBON_00028 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEBBBBON_00029 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
DEBBBBON_00030 8.2e-70 argR K Regulates arginine biosynthesis genes
DEBBBBON_00031 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
DEBBBBON_00032 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DEBBBBON_00033 7e-34 S Protein of unknown function (DUF3021)
DEBBBBON_00034 1.2e-61 KT phosphorelay signal transduction system
DEBBBBON_00036 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEBBBBON_00038 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DEBBBBON_00039 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
DEBBBBON_00040 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
DEBBBBON_00041 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEBBBBON_00042 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
DEBBBBON_00045 2.6e-10
DEBBBBON_00048 1.9e-07
DEBBBBON_00053 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEBBBBON_00054 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
DEBBBBON_00055 5.5e-36 XK27_02060 S Transglycosylase associated protein
DEBBBBON_00056 2.6e-55 badR K DNA-binding transcription factor activity
DEBBBBON_00057 3.5e-97 S reductase
DEBBBBON_00058 6.9e-89 L Integrase core domain protein
DEBBBBON_00059 6.4e-41 L transposition
DEBBBBON_00061 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
DEBBBBON_00062 4.6e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
DEBBBBON_00064 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
DEBBBBON_00065 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEBBBBON_00066 1.1e-83 S Putative small multi-drug export protein
DEBBBBON_00067 6.2e-76 ctsR K Belongs to the CtsR family
DEBBBBON_00068 0.0 clpC O Belongs to the ClpA ClpB family
DEBBBBON_00069 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DEBBBBON_00070 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DEBBBBON_00071 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DEBBBBON_00072 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DEBBBBON_00073 6.9e-144 S SseB protein N-terminal domain
DEBBBBON_00074 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
DEBBBBON_00075 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DEBBBBON_00076 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DEBBBBON_00079 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEBBBBON_00080 1e-84 yacP S RNA-binding protein containing a PIN domain
DEBBBBON_00081 3.4e-155 degV S DegV family
DEBBBBON_00083 1.8e-31 K helix-turn-helix
DEBBBBON_00084 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DEBBBBON_00085 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEBBBBON_00086 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
DEBBBBON_00087 6.1e-195 int L Belongs to the 'phage' integrase family
DEBBBBON_00088 2.4e-30 S Helix-turn-helix domain
DEBBBBON_00089 1.9e-179 S pathogenesis
DEBBBBON_00090 3.3e-09
DEBBBBON_00091 3.2e-267
DEBBBBON_00092 0.0 yddE S AAA-like domain
DEBBBBON_00093 1.1e-71 S TcpE family
DEBBBBON_00094 7.2e-25
DEBBBBON_00095 4.3e-82 S Conjugative transposon protein TcpC
DEBBBBON_00096 1.7e-72
DEBBBBON_00097 3.2e-28
DEBBBBON_00098 3.7e-17 S ParE toxin of type II toxin-antitoxin system, parDE
DEBBBBON_00100 4.2e-231 K Replication initiation factor
DEBBBBON_00101 1.2e-244 ydcQ D Ftsk spoiiie family protein
DEBBBBON_00102 6.5e-49
DEBBBBON_00103 5.4e-36
DEBBBBON_00105 2.2e-52 K sequence-specific DNA binding
DEBBBBON_00107 2.9e-38 S Bacteriophage abortive infection AbiH
DEBBBBON_00108 9.8e-48
DEBBBBON_00109 1.7e-146 E IrrE N-terminal-like domain
DEBBBBON_00110 2.9e-117 K Peptidase S24-like
DEBBBBON_00112 3e-254 mrr V Restriction endonuclease
DEBBBBON_00113 0.0 fokIM 2.1.1.113, 2.1.1.72 L PFAM DNA methylase N-4 N-6
DEBBBBON_00114 4.1e-14 S ParE toxin of type II toxin-antitoxin system, parDE
DEBBBBON_00115 2.6e-35 K sequence-specific DNA binding
DEBBBBON_00117 0.0 S Lantibiotic dehydratase, C terminus
DEBBBBON_00118 2.4e-231 spaC2 V Lanthionine synthetase C family protein
DEBBBBON_00119 4.3e-183 EGP Major facilitator Superfamily
DEBBBBON_00120 5.9e-24 3.6.4.12
DEBBBBON_00121 5.9e-91 3.6.4.12 K Divergent AAA domain protein
DEBBBBON_00122 1.5e-35 K sequence-specific DNA binding
DEBBBBON_00124 0.0 S Lantibiotic dehydratase, C terminus
DEBBBBON_00125 2.4e-231 spaC2 V Lanthionine synthetase C family protein
DEBBBBON_00126 4.3e-183 EGP Major facilitator Superfamily
DEBBBBON_00127 5.9e-24 3.6.4.12
DEBBBBON_00128 5.9e-91 3.6.4.12 K Divergent AAA domain protein
DEBBBBON_00129 7.4e-225 int L Belongs to the 'phage' integrase family
DEBBBBON_00130 1.8e-38 S Helix-turn-helix domain
DEBBBBON_00131 4.9e-173
DEBBBBON_00133 3.4e-75 isp2 S pathogenesis
DEBBBBON_00134 5.7e-91 tnp L Transposase
DEBBBBON_00135 1.7e-224 capA M Bacterial capsule synthesis protein
DEBBBBON_00136 3.6e-39 gcvR T UPF0237 protein
DEBBBBON_00137 1.7e-243 XK27_08635 S UPF0210 protein
DEBBBBON_00138 9.4e-56 ais G Phosphoglycerate mutase
DEBBBBON_00139 1.9e-71 ais G Phosphoglycerate mutase
DEBBBBON_00140 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
DEBBBBON_00141 1.3e-102 acmA 3.2.1.17 NU amidase activity
DEBBBBON_00142 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DEBBBBON_00143 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEBBBBON_00144 9.8e-298 dnaK O Heat shock 70 kDa protein
DEBBBBON_00145 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DEBBBBON_00146 8.5e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DEBBBBON_00147 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
DEBBBBON_00148 3.8e-31 hmpT S membrane
DEBBBBON_00150 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
DEBBBBON_00151 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DEBBBBON_00152 1e-84
DEBBBBON_00153 1.6e-77 sigH K DNA-templated transcription, initiation
DEBBBBON_00154 9.3e-150 ykuT M mechanosensitive ion channel
DEBBBBON_00155 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DEBBBBON_00156 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DEBBBBON_00157 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DEBBBBON_00158 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
DEBBBBON_00159 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
DEBBBBON_00160 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
DEBBBBON_00161 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DEBBBBON_00162 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
DEBBBBON_00163 2.4e-83 nrdI F Belongs to the NrdI family
DEBBBBON_00164 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEBBBBON_00165 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DEBBBBON_00166 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DEBBBBON_00167 3.4e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DEBBBBON_00168 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DEBBBBON_00169 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
DEBBBBON_00170 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DEBBBBON_00171 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DEBBBBON_00172 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
DEBBBBON_00173 6.5e-202 yhjX P Major Facilitator
DEBBBBON_00174 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEBBBBON_00175 5e-94 V VanZ like family
DEBBBBON_00177 1e-123 glnQ E abc transporter atp-binding protein
DEBBBBON_00178 1.8e-276 glnP P ABC transporter
DEBBBBON_00179 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DEBBBBON_00180 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DEBBBBON_00181 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
DEBBBBON_00182 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
DEBBBBON_00183 9.1e-234 sufD O assembly protein SufD
DEBBBBON_00184 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DEBBBBON_00185 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
DEBBBBON_00186 3.5e-274 sufB O assembly protein SufB
DEBBBBON_00187 7e-10 oppA E ABC transporter substrate-binding protein
DEBBBBON_00188 1.4e-133 oppA E ABC transporter substrate-binding protein
DEBBBBON_00189 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEBBBBON_00190 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEBBBBON_00191 4.8e-73 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEBBBBON_00192 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
DEBBBBON_00193 8e-28 oppD P Belongs to the ABC transporter superfamily
DEBBBBON_00194 2.5e-32 oppD P Belongs to the ABC transporter superfamily
DEBBBBON_00195 4.8e-67 oppD P Belongs to the ABC transporter superfamily
DEBBBBON_00196 1.3e-44 oppD P Belongs to the ABC transporter superfamily
DEBBBBON_00197 2.2e-168 oppF P Belongs to the ABC transporter superfamily
DEBBBBON_00200 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DEBBBBON_00201 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEBBBBON_00202 1.9e-223 EGP Major facilitator Superfamily
DEBBBBON_00203 3.1e-72 adcR K transcriptional
DEBBBBON_00204 2.2e-136 adcC P ABC transporter, ATP-binding protein
DEBBBBON_00205 1.6e-127 adcB P ABC transporter (Permease
DEBBBBON_00206 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
DEBBBBON_00207 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
DEBBBBON_00208 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
DEBBBBON_00209 3.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DEBBBBON_00210 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
DEBBBBON_00211 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
DEBBBBON_00212 1.9e-127 yeeN K transcriptional regulatory protein
DEBBBBON_00213 9.8e-50 yajC U protein transport
DEBBBBON_00214 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEBBBBON_00215 5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
DEBBBBON_00216 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DEBBBBON_00217 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DEBBBBON_00218 0.0 WQ51_06230 S ABC transporter substrate binding protein
DEBBBBON_00219 5.2e-142 cmpC S abc transporter atp-binding protein
DEBBBBON_00220 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEBBBBON_00221 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DEBBBBON_00222 4.4e-37 L Transposase
DEBBBBON_00223 6.4e-18 L transposase activity
DEBBBBON_00224 2.8e-69 L Integrase core domain protein
DEBBBBON_00227 4.7e-43
DEBBBBON_00228 6.8e-56 S TM2 domain
DEBBBBON_00229 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DEBBBBON_00230 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DEBBBBON_00231 3.3e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DEBBBBON_00232 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
DEBBBBON_00233 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
DEBBBBON_00234 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
DEBBBBON_00235 6e-55 cof Q phosphatase activity
DEBBBBON_00236 6.2e-35 cof Q phosphatase activity
DEBBBBON_00237 4.7e-79 glcR K transcriptional regulator (DeoR family)
DEBBBBON_00238 3.9e-21 glcR K transcriptional regulator (DeoR family)
DEBBBBON_00239 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DEBBBBON_00240 7.6e-41 K transcriptional
DEBBBBON_00241 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
DEBBBBON_00242 6.5e-67 S COG1073 Hydrolases of the alpha beta superfamily
DEBBBBON_00243 1.1e-65 S COG1073 Hydrolases of the alpha beta superfamily
DEBBBBON_00244 3.5e-274 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DEBBBBON_00245 8.2e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DEBBBBON_00246 3.2e-77 yhaI L Membrane
DEBBBBON_00247 4.6e-260 pepC 3.4.22.40 E aminopeptidase
DEBBBBON_00248 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DEBBBBON_00249 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DEBBBBON_00250 3.1e-95 ypsA S Belongs to the UPF0398 family
DEBBBBON_00251 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DEBBBBON_00252 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DEBBBBON_00253 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
DEBBBBON_00254 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
DEBBBBON_00255 2.5e-23
DEBBBBON_00256 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DEBBBBON_00257 3.1e-20 XK27_09675 K -acetyltransferase
DEBBBBON_00258 9.3e-46 XK27_09675 K -acetyltransferase
DEBBBBON_00259 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DEBBBBON_00260 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DEBBBBON_00261 5.2e-59 L Integrase core domain protein
DEBBBBON_00262 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEBBBBON_00263 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DEBBBBON_00264 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEBBBBON_00265 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
DEBBBBON_00266 1.5e-97 ybhL S Belongs to the BI1 family
DEBBBBON_00269 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DEBBBBON_00270 2e-89 K transcriptional regulator
DEBBBBON_00271 7.6e-36 yneF S UPF0154 protein
DEBBBBON_00272 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DEBBBBON_00273 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEBBBBON_00274 3.5e-99 XK27_09740 S Phosphoesterase
DEBBBBON_00275 5.4e-86 ykuL S CBS domain
DEBBBBON_00276 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
DEBBBBON_00277 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEBBBBON_00278 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEBBBBON_00279 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DEBBBBON_00280 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DEBBBBON_00281 1.2e-258 trkH P Cation transport protein
DEBBBBON_00282 7.6e-247 trkA P Potassium transporter peripheral membrane component
DEBBBBON_00283 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DEBBBBON_00284 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DEBBBBON_00285 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
DEBBBBON_00286 5.6e-161 K sequence-specific DNA binding
DEBBBBON_00287 1.2e-32 V protein secretion by the type I secretion system
DEBBBBON_00288 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DEBBBBON_00289 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DEBBBBON_00290 1.6e-25 V protein secretion by the type I secretion system
DEBBBBON_00291 1.8e-27 comA V protein secretion by the type I secretion system
DEBBBBON_00292 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DEBBBBON_00293 3.7e-22 yhaI L Membrane
DEBBBBON_00294 8.4e-55 S Domain of unknown function (DUF4173)
DEBBBBON_00295 6.8e-95 ureI S AmiS/UreI family transporter
DEBBBBON_00296 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
DEBBBBON_00297 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
DEBBBBON_00298 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
DEBBBBON_00299 6.6e-78 ureE O enzyme active site formation
DEBBBBON_00300 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DEBBBBON_00301 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DEBBBBON_00302 3.4e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DEBBBBON_00303 3.9e-176 cbiM P PDGLE domain
DEBBBBON_00304 1.1e-136 P cobalt transport protein
DEBBBBON_00305 3.1e-130 cbiO P ABC transporter
DEBBBBON_00306 5.1e-24 ET amino acid transport
DEBBBBON_00307 7.3e-118 ET amino acid transport
DEBBBBON_00308 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEBBBBON_00309 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
DEBBBBON_00310 3.8e-205 EGP Transmembrane secretion effector
DEBBBBON_00311 4e-153 ET amino acid transport
DEBBBBON_00312 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
DEBBBBON_00313 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
DEBBBBON_00314 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
DEBBBBON_00315 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
DEBBBBON_00316 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEBBBBON_00317 3e-98 metI P ABC transporter (Permease
DEBBBBON_00318 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DEBBBBON_00319 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
DEBBBBON_00320 8e-94 S UPF0397 protein
DEBBBBON_00321 0.0 ykoD P abc transporter atp-binding protein
DEBBBBON_00322 1.2e-146 cbiQ P cobalt transport
DEBBBBON_00323 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DEBBBBON_00324 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
DEBBBBON_00325 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
DEBBBBON_00326 1.5e-242 P COG0168 Trk-type K transport systems, membrane components
DEBBBBON_00327 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
DEBBBBON_00328 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
DEBBBBON_00329 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DEBBBBON_00330 2.8e-282 T PhoQ Sensor
DEBBBBON_00331 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEBBBBON_00332 6.5e-218 dnaB L Replication initiation and membrane attachment
DEBBBBON_00333 4.4e-166 dnaI L Primosomal protein DnaI
DEBBBBON_00334 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DEBBBBON_00336 1.2e-34
DEBBBBON_00337 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
DEBBBBON_00338 3e-27 L Integrase core domain protein
DEBBBBON_00339 3.4e-50 L transposition
DEBBBBON_00340 5.7e-23 L Transposase
DEBBBBON_00341 7.8e-28 L transposase activity
DEBBBBON_00342 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEBBBBON_00343 4.2e-62 manO S protein conserved in bacteria
DEBBBBON_00344 1.1e-167 manN G PTS system mannose fructose sorbose family IID component
DEBBBBON_00345 2.3e-116 manM G pts system
DEBBBBON_00346 1.1e-181 manL 2.7.1.191 G pts system
DEBBBBON_00347 4.4e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
DEBBBBON_00348 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
DEBBBBON_00349 1.9e-248 pbuO S permease
DEBBBBON_00350 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
DEBBBBON_00351 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
DEBBBBON_00352 2.5e-220 brpA K Transcriptional
DEBBBBON_00353 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
DEBBBBON_00354 3.1e-212 nusA K Participates in both transcription termination and antitermination
DEBBBBON_00355 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
DEBBBBON_00356 1.4e-41 ylxQ J ribosomal protein
DEBBBBON_00357 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEBBBBON_00358 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEBBBBON_00359 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
DEBBBBON_00360 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
DEBBBBON_00361 2.4e-234 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
DEBBBBON_00362 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEBBBBON_00363 3.8e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
DEBBBBON_00364 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
DEBBBBON_00365 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
DEBBBBON_00366 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
DEBBBBON_00368 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
DEBBBBON_00369 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEBBBBON_00370 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DEBBBBON_00371 3.4e-74 ylbF S Belongs to the UPF0342 family
DEBBBBON_00372 7.1e-46 ylbG S UPF0298 protein
DEBBBBON_00373 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
DEBBBBON_00374 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
DEBBBBON_00375 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
DEBBBBON_00376 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
DEBBBBON_00377 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
DEBBBBON_00378 2.8e-70 acuB S IMP dehydrogenase activity
DEBBBBON_00379 3.3e-43 acuB S IMP dehydrogenase activity
DEBBBBON_00380 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DEBBBBON_00381 6.3e-111 yvyE 3.4.13.9 S YigZ family
DEBBBBON_00382 5.3e-253 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
DEBBBBON_00383 1.7e-122 comFC S Competence protein
DEBBBBON_00384 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEBBBBON_00391 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
DEBBBBON_00392 6.4e-108 S Domain of unknown function (DUF1803)
DEBBBBON_00393 1.3e-101 ygaC J Belongs to the UPF0374 family
DEBBBBON_00394 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
DEBBBBON_00395 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEBBBBON_00396 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
DEBBBBON_00397 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
DEBBBBON_00398 1.9e-115 S Haloacid dehalogenase-like hydrolase
DEBBBBON_00399 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
DEBBBBON_00400 4e-72 marR K Transcriptional regulator, MarR family
DEBBBBON_00401 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DEBBBBON_00402 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEBBBBON_00403 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
DEBBBBON_00404 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
DEBBBBON_00405 1.6e-126 IQ reductase
DEBBBBON_00406 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DEBBBBON_00407 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DEBBBBON_00408 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DEBBBBON_00409 4.1e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
DEBBBBON_00410 5.9e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DEBBBBON_00411 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
DEBBBBON_00412 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DEBBBBON_00413 4.4e-126 tnp L Transposase
DEBBBBON_00414 2.1e-206 rny D Endoribonuclease that initiates mRNA decay
DEBBBBON_00415 2.4e-84 L Transposase
DEBBBBON_00416 2.1e-113 fruR K transcriptional
DEBBBBON_00417 3e-162 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DEBBBBON_00418 2.1e-78 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
DEBBBBON_00419 1.7e-156 fruA 2.7.1.202 G phosphotransferase system
DEBBBBON_00420 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
DEBBBBON_00421 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEBBBBON_00422 3e-156 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DEBBBBON_00424 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
DEBBBBON_00425 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEBBBBON_00426 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DEBBBBON_00427 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
DEBBBBON_00428 6.4e-29 2.3.1.128 K acetyltransferase
DEBBBBON_00429 1.7e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
DEBBBBON_00430 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DEBBBBON_00431 2e-126 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEBBBBON_00432 2.6e-64 WQ51_03320 S cog cog4835
DEBBBBON_00433 1.7e-143 XK27_08360 S EDD domain protein, DegV family
DEBBBBON_00434 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DEBBBBON_00435 1.6e-224 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DEBBBBON_00436 0.0 yfmR S abc transporter atp-binding protein
DEBBBBON_00437 1.6e-24 U response to pH
DEBBBBON_00438 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
DEBBBBON_00439 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
DEBBBBON_00440 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DEBBBBON_00441 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DEBBBBON_00442 1.9e-77 K DNA-binding transcription factor activity
DEBBBBON_00443 0.0 lmrA1 V abc transporter atp-binding protein
DEBBBBON_00444 0.0 lmrA2 V abc transporter atp-binding protein
DEBBBBON_00445 5.4e-45 K Acetyltransferase (GNAT) family
DEBBBBON_00446 3.2e-78 sptS 2.7.13.3 T Histidine kinase
DEBBBBON_00447 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DEBBBBON_00448 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DEBBBBON_00449 5.3e-161 cvfB S Protein conserved in bacteria
DEBBBBON_00450 7.4e-35 yozE S Belongs to the UPF0346 family
DEBBBBON_00451 2.5e-118 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
DEBBBBON_00453 1.1e-10 rlpA M LysM domain protein
DEBBBBON_00454 2.6e-32 rlpA M LysM domain protein
DEBBBBON_00455 1.4e-190 phoH T phosphate starvation-inducible protein PhoH
DEBBBBON_00459 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEBBBBON_00460 1.8e-164 K transcriptional regulator (lysR family)
DEBBBBON_00461 1.4e-186 coiA 3.6.4.12 S Competence protein
DEBBBBON_00462 0.0 pepF E oligoendopeptidase F
DEBBBBON_00463 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
DEBBBBON_00464 2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
DEBBBBON_00465 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEBBBBON_00466 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DEBBBBON_00467 1.3e-147 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DEBBBBON_00468 7.9e-104 3.4.17.14, 3.5.1.28 NU amidase activity
DEBBBBON_00469 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
DEBBBBON_00470 1.2e-227 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
DEBBBBON_00471 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DEBBBBON_00472 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DEBBBBON_00473 2.7e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DEBBBBON_00474 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
DEBBBBON_00475 2e-131 yxkH G deacetylase
DEBBBBON_00476 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
DEBBBBON_00477 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DEBBBBON_00478 2.7e-152 rarD S Transporter
DEBBBBON_00479 2.6e-16 T peptidase
DEBBBBON_00480 8.9e-14 coiA 3.6.4.12 S Competence protein
DEBBBBON_00481 8.3e-105 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DEBBBBON_00482 8.1e-69 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DEBBBBON_00483 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DEBBBBON_00484 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEBBBBON_00485 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
DEBBBBON_00486 3.3e-78 atpF C ATP synthase F(0) sector subunit b
DEBBBBON_00487 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEBBBBON_00488 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEBBBBON_00489 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEBBBBON_00490 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEBBBBON_00491 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DEBBBBON_00492 2.8e-230 ftsW D Belongs to the SEDS family
DEBBBBON_00493 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEBBBBON_00494 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DEBBBBON_00495 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEBBBBON_00496 5.4e-161 holB 2.7.7.7 L dna polymerase iii
DEBBBBON_00497 7.5e-133 yaaT S stage 0 sporulation protein
DEBBBBON_00498 9.5e-55 yabA L Involved in initiation control of chromosome replication
DEBBBBON_00499 5e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DEBBBBON_00500 5.8e-225 amt P Ammonium Transporter
DEBBBBON_00501 1.8e-51 glnB K Belongs to the P(II) protein family
DEBBBBON_00502 6e-104 mur1 NU mannosyl-glycoprotein
DEBBBBON_00503 1.6e-143 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
DEBBBBON_00504 1.2e-92 nptA P COG1283 Na phosphate symporter
DEBBBBON_00505 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DEBBBBON_00506 1.8e-53
DEBBBBON_00507 7.5e-26
DEBBBBON_00508 1.5e-59
DEBBBBON_00509 6.1e-63 S membrane
DEBBBBON_00510 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DEBBBBON_00511 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DEBBBBON_00512 4.5e-39 ynzC S UPF0291 protein
DEBBBBON_00513 1.5e-253 cycA E permease
DEBBBBON_00514 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
DEBBBBON_00515 3.1e-47 pts33BCA G pts system
DEBBBBON_00516 3e-150 pts33BCA G pts system
DEBBBBON_00517 4.1e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEBBBBON_00522 1.5e-166 fhuR K transcriptional regulator (lysR family)
DEBBBBON_00523 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEBBBBON_00524 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DEBBBBON_00525 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEBBBBON_00526 4.9e-227 pyrP F uracil Permease
DEBBBBON_00527 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DEBBBBON_00528 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
DEBBBBON_00529 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
DEBBBBON_00530 4.2e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
DEBBBBON_00531 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEBBBBON_00532 2e-36 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DEBBBBON_00533 3.2e-73 V permease protein
DEBBBBON_00534 3.5e-26 ytrF V efflux transmembrane transporter activity
DEBBBBON_00535 1.6e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEBBBBON_00536 1.2e-50 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DEBBBBON_00537 1.3e-108 L Transposase
DEBBBBON_00538 8e-112 L Transposase
DEBBBBON_00539 1.6e-18 L Integrase core domain
DEBBBBON_00542 3e-92 S MucBP domain
DEBBBBON_00543 5.9e-51 M YSIRK type signal peptide
DEBBBBON_00544 4.8e-142 M the current gene model (or a revised gene model) may contain a
DEBBBBON_00546 0.0 mdlB V abc transporter atp-binding protein
DEBBBBON_00547 0.0 lmrA V abc transporter atp-binding protein
DEBBBBON_00548 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DEBBBBON_00549 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DEBBBBON_00550 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
DEBBBBON_00551 2.5e-132 rr02 KT response regulator
DEBBBBON_00552 8.5e-173 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DEBBBBON_00553 2.1e-34 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
DEBBBBON_00554 4.8e-168 V ABC transporter
DEBBBBON_00555 5.4e-122 sagI S ABC-2 type transporter
DEBBBBON_00556 6.9e-197 yceA S Belongs to the UPF0176 family
DEBBBBON_00557 6.9e-19
DEBBBBON_00558 2.5e-141 deoD_1 2.4.2.3 F Phosphorylase superfamily
DEBBBBON_00559 5.6e-113 S VIT family
DEBBBBON_00560 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DEBBBBON_00561 1.7e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
DEBBBBON_00562 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
DEBBBBON_00563 1.6e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
DEBBBBON_00564 4e-248 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DEBBBBON_00565 8.8e-104 GBS0088 J protein conserved in bacteria
DEBBBBON_00566 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
DEBBBBON_00567 1.8e-173 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DEBBBBON_00568 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
DEBBBBON_00569 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DEBBBBON_00570 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEBBBBON_00571 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
DEBBBBON_00572 2.5e-21
DEBBBBON_00573 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEBBBBON_00575 3.5e-07 U protein secretion
DEBBBBON_00576 2.1e-50 U protein secretion
DEBBBBON_00577 1.1e-11 U protein secretion
DEBBBBON_00578 2e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
DEBBBBON_00579 4.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
DEBBBBON_00581 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEBBBBON_00582 2.2e-55 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DEBBBBON_00583 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
DEBBBBON_00584 1.7e-162 S Protein of unknown function (DUF3114)
DEBBBBON_00585 1.2e-22 S Protein of unknown function (DUF3114)
DEBBBBON_00586 1.5e-118 yqfA K protein, Hemolysin III
DEBBBBON_00587 3.6e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
DEBBBBON_00588 1.7e-218 mvaS 2.3.3.10 I synthase
DEBBBBON_00589 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DEBBBBON_00590 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DEBBBBON_00591 9.7e-22
DEBBBBON_00592 7.5e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEBBBBON_00593 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
DEBBBBON_00594 1.5e-250 mmuP E amino acid
DEBBBBON_00595 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
DEBBBBON_00596 1.4e-29 S Domain of unknown function (DUF1912)
DEBBBBON_00597 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
DEBBBBON_00598 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DEBBBBON_00599 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DEBBBBON_00600 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DEBBBBON_00601 8.5e-198 ilvE 2.6.1.42 E Aminotransferase
DEBBBBON_00602 4.8e-16 S Protein of unknown function (DUF2969)
DEBBBBON_00605 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
DEBBBBON_00608 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
DEBBBBON_00609 6.1e-70 M Pfam SNARE associated Golgi protein
DEBBBBON_00610 9.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
DEBBBBON_00611 3e-51 S oxidoreductase
DEBBBBON_00612 3.2e-54 S oxidoreductase
DEBBBBON_00613 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
DEBBBBON_00614 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
DEBBBBON_00615 0.0 clpE O Belongs to the ClpA ClpB family
DEBBBBON_00616 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEBBBBON_00617 1.3e-34 ykuJ S protein conserved in bacteria
DEBBBBON_00618 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
DEBBBBON_00619 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
DEBBBBON_00620 3.1e-78 feoA P FeoA domain protein
DEBBBBON_00621 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DEBBBBON_00622 6.6e-08
DEBBBBON_00623 1.5e-35 yugF I carboxylic ester hydrolase activity
DEBBBBON_00624 7.5e-23 I Alpha/beta hydrolase family
DEBBBBON_00625 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEBBBBON_00626 2.3e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DEBBBBON_00627 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
DEBBBBON_00628 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEBBBBON_00629 1e-63 licT K transcriptional antiterminator
DEBBBBON_00630 6.8e-53 licT K transcriptional antiterminator
DEBBBBON_00631 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEBBBBON_00632 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DEBBBBON_00633 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEBBBBON_00634 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DEBBBBON_00635 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DEBBBBON_00636 2.9e-221 mdtG EGP Major facilitator Superfamily
DEBBBBON_00637 2e-33 secG U Preprotein translocase subunit SecG
DEBBBBON_00638 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DEBBBBON_00639 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DEBBBBON_00640 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEBBBBON_00641 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
DEBBBBON_00642 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
DEBBBBON_00643 4.4e-183 ccpA K Catabolite control protein A
DEBBBBON_00644 6.2e-21 yyaQ S YjbR
DEBBBBON_00645 1.3e-142 yyaQ S YjbR
DEBBBBON_00646 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DEBBBBON_00647 1e-78 yueI S Protein of unknown function (DUF1694)
DEBBBBON_00648 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DEBBBBON_00649 2e-25 WQ51_00785
DEBBBBON_00650 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
DEBBBBON_00651 2e-219 ywbD 2.1.1.191 J Methyltransferase
DEBBBBON_00652 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
DEBBBBON_00653 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DEBBBBON_00654 4.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DEBBBBON_00655 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DEBBBBON_00656 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
DEBBBBON_00657 3.2e-53 yheA S Belongs to the UPF0342 family
DEBBBBON_00658 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DEBBBBON_00659 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DEBBBBON_00660 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DEBBBBON_00661 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
DEBBBBON_00662 1.6e-239 msrR K Transcriptional regulator
DEBBBBON_00663 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
DEBBBBON_00664 2.4e-203 I acyl-CoA dehydrogenase
DEBBBBON_00665 3.2e-95 mip S hydroperoxide reductase activity
DEBBBBON_00666 1.3e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEBBBBON_00667 4.4e-104
DEBBBBON_00668 1e-31 K Cro/C1-type HTH DNA-binding domain
DEBBBBON_00669 3e-49 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
DEBBBBON_00670 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
DEBBBBON_00671 8.1e-95
DEBBBBON_00672 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DEBBBBON_00673 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEBBBBON_00674 2.4e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEBBBBON_00675 3.8e-193 S CRISPR-associated protein Csn2 subfamily St
DEBBBBON_00676 2.4e-147 ycgQ S TIGR03943 family
DEBBBBON_00677 3.2e-156 XK27_03015 S permease
DEBBBBON_00679 0.0 yhgF K Transcriptional accessory protein
DEBBBBON_00680 9.9e-42 pspC KT PspC domain
DEBBBBON_00681 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DEBBBBON_00682 2.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEBBBBON_00684 5.5e-69 ytxH S General stress protein
DEBBBBON_00686 2e-177 yegQ O Peptidase U32
DEBBBBON_00687 3.4e-252 yegQ O Peptidase U32
DEBBBBON_00688 7.1e-87 bioY S biotin synthase
DEBBBBON_00690 3.1e-33 XK27_12190 S protein conserved in bacteria
DEBBBBON_00691 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
DEBBBBON_00692 9.6e-12
DEBBBBON_00693 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
DEBBBBON_00694 0.0 L helicase
DEBBBBON_00695 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DEBBBBON_00696 2.1e-161 M LysM domain
DEBBBBON_00697 7.6e-16
DEBBBBON_00698 7.5e-174 S hydrolase
DEBBBBON_00699 9.6e-115 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
DEBBBBON_00700 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEBBBBON_00701 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
DEBBBBON_00702 2.7e-27 P Hemerythrin HHE cation binding domain protein
DEBBBBON_00703 3.9e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DEBBBBON_00704 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
DEBBBBON_00705 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
DEBBBBON_00706 0.0 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
DEBBBBON_00707 2.5e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
DEBBBBON_00708 2.7e-137 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain protein
DEBBBBON_00709 9.5e-149 L Protein of unknown function (DUF2813)
DEBBBBON_00710 2.6e-92 pcrA1 3.6.4.12 L UvrD/REP helicase N-terminal domain
DEBBBBON_00711 1.4e-10 endA F DNA/RNA non-specific endonuclease
DEBBBBON_00712 1.2e-33
DEBBBBON_00713 1.1e-190 higA K Pfam:DUF955
DEBBBBON_00714 3.4e-175 spd F DNA RNA non-specific endonuclease
DEBBBBON_00715 1.7e-91 lemA S LemA family
DEBBBBON_00716 1.2e-131 htpX O Belongs to the peptidase M48B family
DEBBBBON_00717 4.2e-75 S Psort location CytoplasmicMembrane, score
DEBBBBON_00718 6.2e-56 S Domain of unknown function (DUF4430)
DEBBBBON_00719 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEBBBBON_00720 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
DEBBBBON_00721 2.5e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
DEBBBBON_00722 7e-187 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
DEBBBBON_00723 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DEBBBBON_00724 3.2e-92 dps P Belongs to the Dps family
DEBBBBON_00725 8.9e-80 perR P Belongs to the Fur family
DEBBBBON_00726 1.9e-27 yqgQ S protein conserved in bacteria
DEBBBBON_00727 2.3e-176 glk 2.7.1.2 G Glucokinase
DEBBBBON_00728 0.0 typA T GTP-binding protein TypA
DEBBBBON_00730 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEBBBBON_00731 3.9e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEBBBBON_00732 6.3e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DEBBBBON_00733 3.1e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DEBBBBON_00734 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DEBBBBON_00735 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DEBBBBON_00736 6.8e-96 sepF D cell septum assembly
DEBBBBON_00737 2.6e-34 yggT D integral membrane protein
DEBBBBON_00738 4.2e-144 ylmH T S4 RNA-binding domain
DEBBBBON_00739 1.8e-135 divIVA D Cell division protein DivIVA
DEBBBBON_00740 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEBBBBON_00742 2.6e-228 mntH P Mn2 and Fe2 transporters of the NRAMP family
DEBBBBON_00743 2e-45 rpmE2 J 50S ribosomal protein L31
DEBBBBON_00744 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DEBBBBON_00745 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
DEBBBBON_00746 8.9e-155 gst O Glutathione S-transferase
DEBBBBON_00747 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEBBBBON_00748 2.4e-112 tdk 2.7.1.21 F thymidine kinase
DEBBBBON_00749 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEBBBBON_00750 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DEBBBBON_00751 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DEBBBBON_00752 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEBBBBON_00753 4.5e-67 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DEBBBBON_00754 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEBBBBON_00755 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
DEBBBBON_00756 8e-100 pvaA M lytic transglycosylase activity
DEBBBBON_00757 0.0 yfiB1 V abc transporter atp-binding protein
DEBBBBON_00758 0.0 XK27_10035 V abc transporter atp-binding protein
DEBBBBON_00759 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
DEBBBBON_00760 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEBBBBON_00761 8.7e-237 dltB M Membrane protein involved in D-alanine export
DEBBBBON_00762 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEBBBBON_00763 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DEBBBBON_00764 4.6e-238 L Transposase
DEBBBBON_00765 9.8e-32 L Integrase core domain protein
DEBBBBON_00766 9.6e-32 L transposition
DEBBBBON_00767 6.5e-54 L transposition
DEBBBBON_00768 7.7e-19 L transposase activity
DEBBBBON_00769 0.0 3.6.3.8 P cation transport ATPase
DEBBBBON_00770 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
DEBBBBON_00772 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DEBBBBON_00773 7.3e-166 metF 1.5.1.20 C reductase
DEBBBBON_00774 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
DEBBBBON_00775 1.7e-94 panT S ECF transporter, substrate-specific component
DEBBBBON_00776 5.7e-92 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DEBBBBON_00777 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
DEBBBBON_00778 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DEBBBBON_00779 2.6e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DEBBBBON_00780 2.8e-40 T PhoQ Sensor
DEBBBBON_00781 2.2e-43 T PhoQ Sensor
DEBBBBON_00782 3.6e-88 T PhoQ Sensor
DEBBBBON_00783 6.7e-122 L Helix-turn-helix domain
DEBBBBON_00784 2.2e-162 L integrase core domain
DEBBBBON_00785 3.2e-220 L Transposase
DEBBBBON_00786 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
DEBBBBON_00787 8.9e-206 potD P spermidine putrescine ABC transporter
DEBBBBON_00788 3.1e-268 clcA P Chloride transporter, ClC family
DEBBBBON_00789 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
DEBBBBON_00790 1.9e-21 L Helix-turn-helix domain
DEBBBBON_00791 1.1e-82 L Helix-turn-helix domain
DEBBBBON_00792 9.8e-163 L Integrase core domain protein
DEBBBBON_00793 2.1e-30 rpsT J rRNA binding
DEBBBBON_00794 1.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
DEBBBBON_00795 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
DEBBBBON_00796 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
DEBBBBON_00797 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
DEBBBBON_00798 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DEBBBBON_00799 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DEBBBBON_00800 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
DEBBBBON_00801 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
DEBBBBON_00802 5.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
DEBBBBON_00803 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
DEBBBBON_00804 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
DEBBBBON_00805 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
DEBBBBON_00806 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DEBBBBON_00807 3.1e-81 ypmB S Protein conserved in bacteria
DEBBBBON_00808 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
DEBBBBON_00809 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
DEBBBBON_00810 1.5e-07
DEBBBBON_00811 2.4e-30
DEBBBBON_00812 3e-13
DEBBBBON_00813 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
DEBBBBON_00814 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DEBBBBON_00815 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
DEBBBBON_00816 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
DEBBBBON_00817 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
DEBBBBON_00818 4.2e-18 D nuclear chromosome segregation
DEBBBBON_00819 2.8e-137 yejC S cyclic nucleotide-binding protein
DEBBBBON_00820 1.2e-163 rapZ S Displays ATPase and GTPase activities
DEBBBBON_00821 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DEBBBBON_00822 8.7e-162 whiA K May be required for sporulation
DEBBBBON_00823 6.4e-168 pepD E Dipeptidase
DEBBBBON_00824 5.4e-32 cspD K Cold shock protein domain
DEBBBBON_00825 8e-42 K Cold-Shock Protein
DEBBBBON_00826 0.0 copB 3.6.3.4 P P-type ATPase
DEBBBBON_00827 5.7e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
DEBBBBON_00828 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DEBBBBON_00829 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DEBBBBON_00830 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
DEBBBBON_00831 1.1e-114 V ABC transporter (Permease
DEBBBBON_00832 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
DEBBBBON_00833 1.6e-10
DEBBBBON_00834 9e-98 K Transcriptional regulator, TetR family
DEBBBBON_00835 1.8e-159 czcD P cation diffusion facilitator family transporter
DEBBBBON_00836 1.8e-209 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
DEBBBBON_00837 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
DEBBBBON_00838 6e-08 S Hydrolases of the alpha beta superfamily
DEBBBBON_00839 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
DEBBBBON_00840 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
DEBBBBON_00843 3.4e-143 2.4.2.3 F Phosphorylase superfamily
DEBBBBON_00844 1.2e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
DEBBBBON_00845 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
DEBBBBON_00846 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
DEBBBBON_00848 3.4e-310 FbpA K RNA-binding protein homologous to eukaryotic snRNP
DEBBBBON_00849 3.7e-190
DEBBBBON_00850 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
DEBBBBON_00851 3.5e-28 3.4.13.21 I Protein conserved in bacteria
DEBBBBON_00853 4.5e-116 S TraX protein
DEBBBBON_00854 1.7e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
DEBBBBON_00855 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
DEBBBBON_00856 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DEBBBBON_00857 1.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEBBBBON_00858 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEBBBBON_00859 6.8e-133 cas6 S Pfam:DUF2276
DEBBBBON_00860 0.0 csm1 S CRISPR-associated protein Csm1 family
DEBBBBON_00861 2.5e-62 csm2 L Csm2 Type III-A
DEBBBBON_00862 4.8e-117 csm3 L RAMP superfamily
DEBBBBON_00863 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
DEBBBBON_00864 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
DEBBBBON_00866 3.4e-61 csm6 S Psort location Cytoplasmic, score
DEBBBBON_00867 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DEBBBBON_00868 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEBBBBON_00869 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
DEBBBBON_00871 1.1e-267 dtpT E transporter
DEBBBBON_00872 5e-103 nylA 3.5.1.4 J Belongs to the amidase family
DEBBBBON_00873 5.7e-110 yckB ET Belongs to the bacterial solute-binding protein 3 family
DEBBBBON_00874 1.8e-67 yecS P ABC transporter (Permease
DEBBBBON_00876 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
DEBBBBON_00877 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
DEBBBBON_00878 1.4e-104 yfiF3 K sequence-specific DNA binding
DEBBBBON_00879 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DEBBBBON_00880 1.8e-240 agcS E (Alanine) symporter
DEBBBBON_00881 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DEBBBBON_00882 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
DEBBBBON_00883 1.8e-31 S haloacid dehalogenase-like hydrolase
DEBBBBON_00884 7.8e-61 S haloacid dehalogenase-like hydrolase
DEBBBBON_00885 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DEBBBBON_00886 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
DEBBBBON_00887 6.3e-32 M1-755 P Hemerythrin HHE cation binding domain protein
DEBBBBON_00888 5.4e-95 XK27_04775 S hemerythrin HHE cation binding domain
DEBBBBON_00889 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
DEBBBBON_00890 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEBBBBON_00891 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DEBBBBON_00892 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DEBBBBON_00893 1.9e-43 yktA S Belongs to the UPF0223 family
DEBBBBON_00894 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
DEBBBBON_00895 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
DEBBBBON_00896 3.3e-158 pstS P phosphate
DEBBBBON_00897 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
DEBBBBON_00898 1.2e-155 pstA P phosphate transport system permease
DEBBBBON_00899 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEBBBBON_00900 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEBBBBON_00901 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
DEBBBBON_00902 0.0 pepN 3.4.11.2 E aminopeptidase
DEBBBBON_00903 1.2e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
DEBBBBON_00904 7.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
DEBBBBON_00905 6.7e-18
DEBBBBON_00906 3.7e-09
DEBBBBON_00907 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DEBBBBON_00908 1.3e-303 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
DEBBBBON_00909 2.3e-23 L Transposase
DEBBBBON_00910 4.6e-25 tatA U protein secretion
DEBBBBON_00911 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DEBBBBON_00912 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
DEBBBBON_00913 5.6e-233 ycdB P peroxidase
DEBBBBON_00914 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
DEBBBBON_00915 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DEBBBBON_00916 4.1e-84 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DEBBBBON_00917 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DEBBBBON_00918 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DEBBBBON_00919 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
DEBBBBON_00920 1.9e-37 3.5.1.28 NU amidase activity
DEBBBBON_00921 8.5e-266 3.5.1.28 NU amidase activity
DEBBBBON_00922 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DEBBBBON_00923 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
DEBBBBON_00924 0.0 lpdA 1.8.1.4 C Dehydrogenase
DEBBBBON_00925 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DEBBBBON_00926 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
DEBBBBON_00927 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
DEBBBBON_00928 5e-38 P membrane protein (DUF2207)
DEBBBBON_00929 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
DEBBBBON_00930 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DEBBBBON_00931 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEBBBBON_00932 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DEBBBBON_00933 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
DEBBBBON_00934 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
DEBBBBON_00935 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
DEBBBBON_00936 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
DEBBBBON_00937 1.1e-158 rssA S Phospholipase, patatin family
DEBBBBON_00938 1e-105 estA E Lysophospholipase L1 and related esterases
DEBBBBON_00939 1.4e-292 S unusual protein kinase
DEBBBBON_00940 4.9e-39 S granule-associated protein
DEBBBBON_00941 8.3e-117 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEBBBBON_00942 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEBBBBON_00943 1.3e-199 S hmm pf01594
DEBBBBON_00944 1.1e-87 G Belongs to the phosphoglycerate mutase family
DEBBBBON_00945 1.4e-88 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
DEBBBBON_00946 2.2e-94 V VanZ like family
DEBBBBON_00947 2.8e-196 wbbI M transferase activity, transferring glycosyl groups
DEBBBBON_00948 2.2e-178 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
DEBBBBON_00949 7.4e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
DEBBBBON_00950 1.8e-243 epsU S Polysaccharide biosynthesis protein
DEBBBBON_00951 1.1e-81 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
DEBBBBON_00953 1e-168 M Glycosyltransferase, group 2 family protein
DEBBBBON_00954 9.2e-60 ycbI M Glycosyl transferase family 2
DEBBBBON_00955 1.1e-17
DEBBBBON_00956 4.7e-97 M Glycosyltransferase sugar-binding region containing DXD motif
DEBBBBON_00957 5.5e-70 pssE S Glycosyltransferase family 28 C-terminal domain
DEBBBBON_00958 5.8e-82 cpsF M Oligosaccharide biosynthesis protein Alg14 like
DEBBBBON_00959 8.1e-67 cpsE M Bacterial sugar transferase
DEBBBBON_00960 2.1e-86 cpsE M Bacterial sugar transferase
DEBBBBON_00961 1.7e-23 rgpAc GT4 M group 1 family protein
DEBBBBON_00962 2.6e-250 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
DEBBBBON_00963 7.2e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
DEBBBBON_00964 3.6e-107 cps4C M biosynthesis protein
DEBBBBON_00965 2.3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
DEBBBBON_00966 5e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
DEBBBBON_00967 9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
DEBBBBON_00968 7.4e-28 yfeJ 6.3.5.2 F glutamine amidotransferase
DEBBBBON_00969 2.7e-77 yfeJ 6.3.5.2 F glutamine amidotransferase
DEBBBBON_00970 1.9e-60 clcA_2 P chloride
DEBBBBON_00971 4.1e-64 clcA_2 P chloride
DEBBBBON_00972 1.3e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DEBBBBON_00973 7.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
DEBBBBON_00974 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DEBBBBON_00976 5.7e-08 V Glucan-binding protein C
DEBBBBON_00977 4e-21 V Glucan-binding protein C
DEBBBBON_00978 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
DEBBBBON_00979 6.9e-275 pepV 3.5.1.18 E Dipeptidase
DEBBBBON_00980 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DEBBBBON_00981 4.1e-42 XK27_03610 K Gnat family
DEBBBBON_00982 3e-33 L COG1943 Transposase and inactivated derivatives
DEBBBBON_00983 5.8e-42 L Transposase
DEBBBBON_00984 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEBBBBON_00985 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DEBBBBON_00986 5.9e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEBBBBON_00987 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DEBBBBON_00988 2.8e-18 M LysM domain
DEBBBBON_00989 2.9e-90 ebsA S Family of unknown function (DUF5322)
DEBBBBON_00990 1e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DEBBBBON_00991 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DEBBBBON_00992 2.4e-223 G COG0457 FOG TPR repeat
DEBBBBON_00993 4e-175 yubA S permease
DEBBBBON_00994 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
DEBBBBON_00995 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
DEBBBBON_00996 2.5e-124 ftsE D cell division ATP-binding protein FtsE
DEBBBBON_00997 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEBBBBON_00998 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DEBBBBON_00999 1.3e-181 yjjH S Calcineurin-like phosphoesterase
DEBBBBON_01000 6.7e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DEBBBBON_01001 0.0 pacL 3.6.3.8 P cation transport ATPase
DEBBBBON_01002 2.6e-67 ywiB S Domain of unknown function (DUF1934)
DEBBBBON_01003 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
DEBBBBON_01004 9.2e-147 yidA S hydrolases of the HAD superfamily
DEBBBBON_01005 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
DEBBBBON_01006 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
DEBBBBON_01007 1.4e-245 vicK 2.7.13.3 T Histidine kinase
DEBBBBON_01008 2.9e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DEBBBBON_01009 3.3e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
DEBBBBON_01010 4.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
DEBBBBON_01011 5.9e-118 gltJ P ABC transporter (Permease
DEBBBBON_01012 1.7e-111 tcyB_2 P ABC transporter (permease)
DEBBBBON_01013 2.4e-124 endA F DNA RNA non-specific endonuclease
DEBBBBON_01014 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
DEBBBBON_01015 6.5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEBBBBON_01017 1e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DEBBBBON_01018 4.7e-131 G Domain of unknown function (DUF4832)
DEBBBBON_01019 1.6e-33 P VTC domain
DEBBBBON_01020 3.9e-47 P VTC domain
DEBBBBON_01021 5.4e-218 cotH M CotH kinase protein
DEBBBBON_01022 1.4e-185 pelG M Putative exopolysaccharide Exporter (EPS-E)
DEBBBBON_01023 3.6e-271 pelF GT4 M Domain of unknown function (DUF3492)
DEBBBBON_01024 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
DEBBBBON_01025 3.8e-72
DEBBBBON_01026 3.9e-72
DEBBBBON_01027 0.0 5.1.3.2 GM Psort location CytoplasmicMembrane, score
DEBBBBON_01028 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEBBBBON_01029 1.2e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DEBBBBON_01030 4.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEBBBBON_01031 2.7e-88 ytsP 1.8.4.14 T GAF domain-containing protein
DEBBBBON_01032 4.6e-163 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEBBBBON_01033 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
DEBBBBON_01036 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DEBBBBON_01037 6.1e-219 XK27_05110 P chloride
DEBBBBON_01038 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
DEBBBBON_01039 6.4e-282 clcA P Chloride transporter, ClC family
DEBBBBON_01040 2.3e-75 fld C Flavodoxin
DEBBBBON_01042 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
DEBBBBON_01043 3.5e-151 estA CE1 S Putative esterase
DEBBBBON_01044 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEBBBBON_01045 1.2e-135 XK27_08845 S abc transporter atp-binding protein
DEBBBBON_01046 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
DEBBBBON_01047 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
DEBBBBON_01048 1.6e-16 S Domain of unknown function (DUF4649)
DEBBBBON_01050 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
DEBBBBON_01051 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
DEBBBBON_01052 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
DEBBBBON_01053 1.1e-112 L Transposase, Mutator family
DEBBBBON_01054 7.1e-89 L Transposase
DEBBBBON_01055 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
DEBBBBON_01056 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
DEBBBBON_01057 8.5e-154 glcU U Glucose uptake
DEBBBBON_01058 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
DEBBBBON_01059 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
DEBBBBON_01060 1.6e-77 XK27_10720 D peptidase activity
DEBBBBON_01061 4.7e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
DEBBBBON_01062 1.7e-08
DEBBBBON_01064 1.2e-172 yeiH S Membrane
DEBBBBON_01065 5.5e-119 mur1 NU muramidase
DEBBBBON_01066 1.9e-83 L transposition
DEBBBBON_01067 2.6e-166 cpsY K Transcriptional regulator
DEBBBBON_01068 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DEBBBBON_01069 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
DEBBBBON_01070 4e-105 artQ P ABC transporter (Permease
DEBBBBON_01071 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
DEBBBBON_01072 1.2e-157 aatB ET ABC transporter substrate-binding protein
DEBBBBON_01073 2.1e-73 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEBBBBON_01074 1.9e-110 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEBBBBON_01075 2.1e-07
DEBBBBON_01076 6.6e-62 adhP 1.1.1.1 C alcohol dehydrogenase
DEBBBBON_01077 6.1e-112 adhP 1.1.1.1 C alcohol dehydrogenase
DEBBBBON_01079 3e-21
DEBBBBON_01080 0.0 res_1 3.1.21.5 S Type III restriction
DEBBBBON_01081 1.3e-248 sthIM 2.1.1.72 L DNA methylase
DEBBBBON_01082 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DEBBBBON_01083 2e-126 gntR1 K transcriptional
DEBBBBON_01084 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DEBBBBON_01085 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DEBBBBON_01086 2.4e-87 niaX
DEBBBBON_01087 7.8e-91 niaR S small molecule binding protein (contains 3H domain)
DEBBBBON_01088 1.6e-128 K DNA-binding helix-turn-helix protein
DEBBBBON_01089 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DEBBBBON_01090 1.2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEBBBBON_01091 3.7e-168 GK ROK family
DEBBBBON_01092 8.3e-159 dprA LU DNA protecting protein DprA
DEBBBBON_01093 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEBBBBON_01094 5.1e-153 S TraX protein
DEBBBBON_01095 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DEBBBBON_01096 2.8e-252 T PhoQ Sensor
DEBBBBON_01097 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DEBBBBON_01098 3.2e-152 XK27_05470 E Methionine synthase
DEBBBBON_01099 7.5e-21 XK27_05470 E Methionine synthase
DEBBBBON_01100 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
DEBBBBON_01101 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEBBBBON_01102 1.8e-51 IQ Acetoin reductase
DEBBBBON_01103 3.9e-19 IQ Acetoin reductase
DEBBBBON_01104 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DEBBBBON_01105 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DEBBBBON_01108 2.5e-211 pqqE C radical SAM domain protein
DEBBBBON_01109 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
DEBBBBON_01110 6.6e-61 EGP Major facilitator Superfamily
DEBBBBON_01111 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DEBBBBON_01112 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
DEBBBBON_01113 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DEBBBBON_01114 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DEBBBBON_01115 0.0 dnaE 2.7.7.7 L DNA polymerase
DEBBBBON_01116 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
DEBBBBON_01117 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DEBBBBON_01118 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DEBBBBON_01119 2.5e-43 ysdA L Membrane
DEBBBBON_01120 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DEBBBBON_01121 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DEBBBBON_01122 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DEBBBBON_01123 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
DEBBBBON_01125 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DEBBBBON_01126 1.7e-83 ypmS S Protein conserved in bacteria
DEBBBBON_01127 6e-144 ypmR E lipolytic protein G-D-S-L family
DEBBBBON_01128 1e-148 DegV S DegV family
DEBBBBON_01129 2.2e-304 recN L May be involved in recombinational repair of damaged DNA
DEBBBBON_01130 1.8e-72 argR K Regulates arginine biosynthesis genes
DEBBBBON_01131 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DEBBBBON_01132 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DEBBBBON_01133 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
DEBBBBON_01134 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DEBBBBON_01136 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DEBBBBON_01137 2.9e-125 dnaD
DEBBBBON_01138 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DEBBBBON_01139 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEBBBBON_01140 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
DEBBBBON_01141 1.1e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DEBBBBON_01142 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DEBBBBON_01143 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
DEBBBBON_01144 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DEBBBBON_01145 5.6e-240 rodA D Belongs to the SEDS family
DEBBBBON_01146 2.2e-48 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
DEBBBBON_01147 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DEBBBBON_01148 4e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DEBBBBON_01149 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DEBBBBON_01150 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DEBBBBON_01151 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
DEBBBBON_01152 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DEBBBBON_01153 1.2e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
DEBBBBON_01154 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DEBBBBON_01155 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DEBBBBON_01157 2.5e-30 L Integrase core domain protein
DEBBBBON_01158 1.6e-55 L transposition
DEBBBBON_01159 8.2e-22 L Transposase
DEBBBBON_01160 5.2e-36 L transposase activity
DEBBBBON_01161 1.3e-22 XK27_08085
DEBBBBON_01162 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
DEBBBBON_01163 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
DEBBBBON_01164 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
DEBBBBON_01165 1.1e-121 ylfI S tigr01906
DEBBBBON_01166 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DEBBBBON_01167 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
DEBBBBON_01168 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
DEBBBBON_01171 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DEBBBBON_01172 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DEBBBBON_01173 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DEBBBBON_01174 1.1e-206 yurR 1.4.5.1 E oxidoreductase
DEBBBBON_01175 1.4e-64 zupT P Mediates zinc uptake. May also transport other divalent cations
DEBBBBON_01176 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEBBBBON_01177 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
DEBBBBON_01178 1.7e-70 gtrA S GtrA-like protein
DEBBBBON_01179 7.4e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEBBBBON_01180 6e-169 ybbR S Protein conserved in bacteria
DEBBBBON_01181 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DEBBBBON_01182 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
DEBBBBON_01183 8.7e-150 cobQ S glutamine amidotransferase
DEBBBBON_01184 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEBBBBON_01185 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
DEBBBBON_01186 0.0 uup S abc transporter atp-binding protein
DEBBBBON_01187 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
DEBBBBON_01188 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
DEBBBBON_01189 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DEBBBBON_01190 9.5e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
DEBBBBON_01191 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEBBBBON_01192 7.9e-39 ptsH G phosphocarrier protein Hpr
DEBBBBON_01193 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
DEBBBBON_01194 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
DEBBBBON_01195 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DEBBBBON_01196 2.2e-34 nrdH O Glutaredoxin
DEBBBBON_01197 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEBBBBON_01198 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DEBBBBON_01200 4.2e-71 L Transposase (IS116 IS110 IS902 family)
DEBBBBON_01201 3.3e-26 L Transposase (IS116 IS110 IS902 family)
DEBBBBON_01202 1.2e-164 ypuA S secreted protein
DEBBBBON_01203 1e-53 yaeR E COG0346 Lactoylglutathione lyase and related lyases
DEBBBBON_01204 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
DEBBBBON_01205 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEBBBBON_01206 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DEBBBBON_01207 3.4e-258 noxE P NADH oxidase
DEBBBBON_01208 1.9e-294 yfmM S abc transporter atp-binding protein
DEBBBBON_01209 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
DEBBBBON_01210 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
DEBBBBON_01211 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
DEBBBBON_01212 2e-86 S ECF-type riboflavin transporter, S component
DEBBBBON_01214 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
DEBBBBON_01215 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
DEBBBBON_01217 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DEBBBBON_01218 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DEBBBBON_01219 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEBBBBON_01220 0.0 smc D Required for chromosome condensation and partitioning
DEBBBBON_01221 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DEBBBBON_01222 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEBBBBON_01223 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEBBBBON_01224 2.4e-92 pat 2.3.1.183 M acetyltransferase
DEBBBBON_01225 3e-13
DEBBBBON_01226 6.3e-23
DEBBBBON_01227 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEBBBBON_01228 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DEBBBBON_01229 7e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
DEBBBBON_01230 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
DEBBBBON_01231 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
DEBBBBON_01232 4.3e-26
DEBBBBON_01233 7.1e-144 S ABC-2 family transporter protein
DEBBBBON_01234 3.6e-97 S transport system, permease component
DEBBBBON_01235 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DEBBBBON_01236 2e-192 desK 2.7.13.3 T Histidine kinase
DEBBBBON_01237 1.4e-133 yvfS V ABC-2 type transporter
DEBBBBON_01238 2.9e-154 XK27_09825 V abc transporter atp-binding protein
DEBBBBON_01242 3.3e-212 EGP Major facilitator Superfamily
DEBBBBON_01243 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
DEBBBBON_01244 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
DEBBBBON_01245 4.6e-42 3.6.1.55 F NUDIX domain
DEBBBBON_01247 3.7e-122 S An automated process has identified a potential problem with this gene model
DEBBBBON_01248 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
DEBBBBON_01249 1.8e-15 liaI KT membrane
DEBBBBON_01250 2.6e-30 liaI KT membrane
DEBBBBON_01251 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
DEBBBBON_01252 0.0 V ABC transporter (permease)
DEBBBBON_01253 1.9e-133 macB2 V ABC transporter, ATP-binding protein
DEBBBBON_01254 6.2e-166 T Histidine kinase
DEBBBBON_01255 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
DEBBBBON_01256 1e-49 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DEBBBBON_01257 3.3e-69 pbuX F xanthine permease
DEBBBBON_01258 9.2e-119 pbuX F xanthine permease
DEBBBBON_01259 1.5e-247 norM V Multidrug efflux pump
DEBBBBON_01260 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEBBBBON_01261 1.5e-234 brnQ E Component of the transport system for branched-chain amino acids
DEBBBBON_01262 1.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
DEBBBBON_01263 1.4e-56 manA 5.3.1.8 G mannose-6-phosphate isomerase
DEBBBBON_01264 4.8e-25 csbD K CsbD-like
DEBBBBON_01265 6.2e-228 yfnA E amino acid
DEBBBBON_01266 5.1e-110 XK27_02070 S nitroreductase
DEBBBBON_01267 2.2e-140 1.13.11.2 S glyoxalase
DEBBBBON_01268 1.6e-76 ywnA K Transcriptional regulator
DEBBBBON_01269 8.9e-156 E Alpha/beta hydrolase of unknown function (DUF915)
DEBBBBON_01270 4.3e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEBBBBON_01271 1.4e-110 drgA C Nitroreductase
DEBBBBON_01272 1.9e-101 yoaK S Protein of unknown function (DUF1275)
DEBBBBON_01273 6.8e-161 yvgN C reductase
DEBBBBON_01274 5.7e-180 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DEBBBBON_01275 2.7e-285 XK27_07020 S Belongs to the UPF0371 family
DEBBBBON_01277 4.8e-55 K response regulator
DEBBBBON_01278 2.5e-31 S Signal peptide protein, YSIRK family
DEBBBBON_01279 2.6e-31 S Signal peptide protein, YSIRK family
DEBBBBON_01281 1.1e-59
DEBBBBON_01282 7.5e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEBBBBON_01283 1e-137
DEBBBBON_01284 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
DEBBBBON_01285 2.7e-26 IQ PFAM AMP-dependent synthetase and ligase
DEBBBBON_01286 5.8e-109 MA20_06410 E LysE type translocator
DEBBBBON_01287 5.6e-08
DEBBBBON_01288 2.7e-09
DEBBBBON_01289 0.0 M family 8
DEBBBBON_01291 1.1e-151 V MatE
DEBBBBON_01293 3.9e-110 C Fe-S oxidoreductases
DEBBBBON_01294 1.2e-176 EGP Major Facilitator Superfamily
DEBBBBON_01295 5.5e-258 I radical SAM domain protein
DEBBBBON_01297 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DEBBBBON_01298 1.4e-150 L Integrase core domain protein
DEBBBBON_01299 1.8e-87 L transposase activity
DEBBBBON_01301 1.4e-84
DEBBBBON_01302 0.0 sbcC L ATPase involved in DNA repair
DEBBBBON_01303 1.5e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DEBBBBON_01304 0.0 lacL 3.2.1.23 G -beta-galactosidase
DEBBBBON_01305 0.0 lacS G transporter
DEBBBBON_01306 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DEBBBBON_01307 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DEBBBBON_01308 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
DEBBBBON_01309 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEBBBBON_01310 2.3e-184 galR K Transcriptional regulator
DEBBBBON_01311 2.7e-08 L Integrase core domain protein
DEBBBBON_01312 1.2e-25 L transposition
DEBBBBON_01313 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
DEBBBBON_01314 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
DEBBBBON_01315 2.5e-101 V abc transporter atp-binding protein
DEBBBBON_01316 4.3e-40 V abc transporter atp-binding protein
DEBBBBON_01317 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
DEBBBBON_01318 5.1e-87 L Transposase
DEBBBBON_01319 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DEBBBBON_01320 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
DEBBBBON_01321 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DEBBBBON_01322 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEBBBBON_01325 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
DEBBBBON_01326 5.8e-175 vraS 2.7.13.3 T Histidine kinase
DEBBBBON_01327 3.7e-120 yvqF KT membrane
DEBBBBON_01328 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
DEBBBBON_01329 2e-132 stp 3.1.3.16 T phosphatase
DEBBBBON_01330 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEBBBBON_01331 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEBBBBON_01332 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DEBBBBON_01333 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
DEBBBBON_01334 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DEBBBBON_01335 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DEBBBBON_01336 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
DEBBBBON_01337 6.3e-148 supH S overlaps another CDS with the same product name
DEBBBBON_01338 3.3e-62 yvoA_1 K Transcriptional
DEBBBBON_01339 2.8e-120 skfE V abc transporter atp-binding protein
DEBBBBON_01340 1.3e-132 V ATPase activity
DEBBBBON_01341 4.3e-172 oppF P Belongs to the ABC transporter superfamily
DEBBBBON_01342 2.2e-204 oppD P Belongs to the ABC transporter superfamily
DEBBBBON_01343 4.9e-168 amiD P ABC transporter (Permease
DEBBBBON_01344 4.2e-278 amiC P ABC transporter (Permease
DEBBBBON_01345 8.3e-140 amiA E ABC transporter, substrate-binding protein, family 5
DEBBBBON_01346 0.0 amiA E ABC transporter, substrate-binding protein, family 5
DEBBBBON_01347 1.2e-24 oppF P Belongs to the ABC transporter superfamily
DEBBBBON_01348 1.1e-44 oppF P Belongs to the ABC transporter superfamily
DEBBBBON_01349 1.4e-40 tatD L Hydrolase, tatd
DEBBBBON_01350 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
DEBBBBON_01351 8.8e-110 L Integrase core domain protein
DEBBBBON_01352 1.1e-23 L transposase activity
DEBBBBON_01353 8.9e-18 L transposase activity
DEBBBBON_01354 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DEBBBBON_01355 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DEBBBBON_01356 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEBBBBON_01357 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
DEBBBBON_01358 1.5e-103 yjbK S Adenylate cyclase
DEBBBBON_01359 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEBBBBON_01360 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
DEBBBBON_01361 2e-58 XK27_04120 S Putative amino acid metabolism
DEBBBBON_01362 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DEBBBBON_01363 1.6e-131 puuD T peptidase C26
DEBBBBON_01364 6.2e-120 radC E Belongs to the UPF0758 family
DEBBBBON_01365 1.7e-268 M Psort location CytoplasmicMembrane, score
DEBBBBON_01366 0.0 rgpF M Rhamnan synthesis protein F
DEBBBBON_01367 4.5e-305 GT4 M transferase activity, transferring glycosyl groups
DEBBBBON_01368 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
DEBBBBON_01369 2.1e-143 rgpC GM Transport permease protein
DEBBBBON_01370 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
DEBBBBON_01371 5.2e-228 rgpA GT4 M Domain of unknown function (DUF1972)
DEBBBBON_01372 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
DEBBBBON_01373 4.6e-42 S Uncharacterized conserved protein (DUF2304)
DEBBBBON_01374 6.9e-130 arnC M group 2 family protein
DEBBBBON_01375 4.7e-182 cpsIaJ S Glycosyltransferase like family 2
DEBBBBON_01376 1e-184 S Glycosyltransferase like family 2
DEBBBBON_01377 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
DEBBBBON_01378 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DEBBBBON_01379 2.9e-235 S Predicted membrane protein (DUF2142)
DEBBBBON_01380 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
DEBBBBON_01381 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
DEBBBBON_01382 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DEBBBBON_01383 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DEBBBBON_01384 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DEBBBBON_01385 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
DEBBBBON_01386 1.6e-202 arcT 2.6.1.1 E Aminotransferase
DEBBBBON_01387 9.4e-136 ET ABC transporter
DEBBBBON_01388 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
DEBBBBON_01389 2.9e-84 mutT 3.6.1.55 F Nudix family
DEBBBBON_01390 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DEBBBBON_01392 2.3e-46 V CAAX protease self-immunity
DEBBBBON_01393 2.4e-33 S CAAX amino terminal protease family protein
DEBBBBON_01394 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
DEBBBBON_01395 1.8e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
DEBBBBON_01396 1.1e-16 XK27_00735
DEBBBBON_01397 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEBBBBON_01399 8.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DEBBBBON_01402 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
DEBBBBON_01403 3e-37 ycaO O OsmC-like protein
DEBBBBON_01405 5.5e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
DEBBBBON_01407 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
DEBBBBON_01408 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEBBBBON_01409 6e-154 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DEBBBBON_01410 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DEBBBBON_01411 9.3e-239 L Transposase
DEBBBBON_01412 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
DEBBBBON_01413 4.8e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DEBBBBON_01414 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEBBBBON_01415 2.8e-108 3.1.3.18 S IA, variant 1
DEBBBBON_01416 2.2e-117 lrgB M effector of murein hydrolase
DEBBBBON_01417 1.7e-55 lrgA S Effector of murein hydrolase LrgA
DEBBBBON_01419 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
DEBBBBON_01420 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
DEBBBBON_01421 1.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEBBBBON_01422 6.6e-104 wecD M Acetyltransferase GNAT family
DEBBBBON_01423 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DEBBBBON_01424 5.1e-96 GK ROK family
DEBBBBON_01425 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
DEBBBBON_01426 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
DEBBBBON_01427 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
DEBBBBON_01428 2.3e-206 potD P spermidine putrescine ABC transporter
DEBBBBON_01429 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
DEBBBBON_01430 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
DEBBBBON_01431 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DEBBBBON_01432 5.1e-170 murB 1.3.1.98 M cell wall formation
DEBBBBON_01433 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DEBBBBON_01434 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DEBBBBON_01435 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
DEBBBBON_01436 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DEBBBBON_01437 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
DEBBBBON_01438 0.0 ydaO E amino acid
DEBBBBON_01439 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DEBBBBON_01440 4.1e-37 ylqC L Belongs to the UPF0109 family
DEBBBBON_01441 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DEBBBBON_01442 7.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
DEBBBBON_01443 2.6e-157 xth 3.1.11.2 L exodeoxyribonuclease III
DEBBBBON_01444 2.1e-74 S QueT transporter
DEBBBBON_01445 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
DEBBBBON_01446 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
DEBBBBON_01447 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
DEBBBBON_01448 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEBBBBON_01449 4.8e-85 ccl S cog cog4708
DEBBBBON_01450 1e-160 rbn E Belongs to the UPF0761 family
DEBBBBON_01451 1.9e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
DEBBBBON_01452 3.3e-231 ytoI K transcriptional regulator containing CBS domains
DEBBBBON_01453 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
DEBBBBON_01454 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEBBBBON_01455 0.0 comEC S Competence protein ComEC
DEBBBBON_01456 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
DEBBBBON_01457 1.7e-142 plsC 2.3.1.51 I Acyltransferase
DEBBBBON_01458 2.7e-93 nodB3 G deacetylase
DEBBBBON_01459 4e-33 nodB3 G deacetylase
DEBBBBON_01460 7.1e-141 yabB 2.1.1.223 L Methyltransferase
DEBBBBON_01461 1e-41 yazA L endonuclease containing a URI domain
DEBBBBON_01462 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DEBBBBON_01463 2.3e-154 corA P CorA-like protein
DEBBBBON_01464 1.9e-62 yjqA S Bacterial PH domain
DEBBBBON_01465 2.3e-99 thiT S Thiamine transporter
DEBBBBON_01466 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DEBBBBON_01467 8.7e-174 yjbB G Permeases of the major facilitator superfamily
DEBBBBON_01468 8.9e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DEBBBBON_01469 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
DEBBBBON_01470 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DEBBBBON_01474 1.1e-155 cjaA ET ABC transporter substrate-binding protein
DEBBBBON_01475 3.8e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
DEBBBBON_01476 3e-106 P ABC transporter (Permease
DEBBBBON_01477 6e-115 papP P ABC transporter (Permease
DEBBBBON_01478 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DEBBBBON_01479 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
DEBBBBON_01480 0.0 copA 3.6.3.54 P P-type ATPase
DEBBBBON_01481 2.7e-73 copY K Copper transport repressor, CopY TcrY family
DEBBBBON_01482 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DEBBBBON_01483 1.9e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DEBBBBON_01484 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
DEBBBBON_01485 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
DEBBBBON_01486 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DEBBBBON_01487 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
DEBBBBON_01488 8.2e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DEBBBBON_01489 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
DEBBBBON_01490 5.4e-53
DEBBBBON_01491 0.0 ctpE P E1-E2 ATPase
DEBBBBON_01492 3.9e-26
DEBBBBON_01493 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEBBBBON_01494 9.7e-28 L transposase activity
DEBBBBON_01495 2.7e-129 K transcriptional regulator, MerR family
DEBBBBON_01496 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
DEBBBBON_01497 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
DEBBBBON_01498 7.4e-64 XK27_02560 S cog cog2151
DEBBBBON_01499 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DEBBBBON_01500 7.7e-227 ytfP S Flavoprotein
DEBBBBON_01502 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DEBBBBON_01503 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
DEBBBBON_01504 2.7e-183 ecsB U ABC transporter
DEBBBBON_01505 2.3e-133 ecsA V abc transporter atp-binding protein
DEBBBBON_01506 1.1e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
DEBBBBON_01507 2.1e-11
DEBBBBON_01508 2.6e-55 S CD20-like family
DEBBBBON_01509 7.3e-107
DEBBBBON_01510 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
DEBBBBON_01511 6.9e-206 ylbM S Belongs to the UPF0348 family
DEBBBBON_01512 2e-140 yqeM Q Methyltransferase domain protein
DEBBBBON_01513 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DEBBBBON_01514 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
DEBBBBON_01515 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEBBBBON_01516 3.5e-49 yhbY J RNA-binding protein
DEBBBBON_01517 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
DEBBBBON_01518 1.8e-98 yqeG S hydrolase of the HAD superfamily
DEBBBBON_01519 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
DEBBBBON_01520 3.6e-51
DEBBBBON_01521 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEBBBBON_01522 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DEBBBBON_01523 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEBBBBON_01524 1.8e-30 M lipopolysaccharide 3-alpha-galactosyltransferase activity
DEBBBBON_01525 3.6e-257 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEBBBBON_01526 5.1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEBBBBON_01527 3.1e-153 hlpA M Belongs to the NlpA lipoprotein family
DEBBBBON_01528 2.7e-97 pncA Q isochorismatase
DEBBBBON_01529 1.7e-137 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DEBBBBON_01530 6.9e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
DEBBBBON_01531 2.4e-75 XK27_03180 T universal stress protein
DEBBBBON_01534 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEBBBBON_01535 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
DEBBBBON_01536 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
DEBBBBON_01537 0.0 yjcE P NhaP-type Na H and K H antiporters
DEBBBBON_01539 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
DEBBBBON_01540 1.3e-184 yhcC S radical SAM protein
DEBBBBON_01541 2.3e-196 ylbL T Belongs to the peptidase S16 family
DEBBBBON_01542 1.3e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEBBBBON_01543 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
DEBBBBON_01544 3.2e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DEBBBBON_01545 3.2e-09 S Protein of unknown function (DUF4059)
DEBBBBON_01546 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
DEBBBBON_01547 3e-162 yxeN P ABC transporter (Permease
DEBBBBON_01548 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
DEBBBBON_01550 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEBBBBON_01551 0.0 pflB 2.3.1.54 C formate acetyltransferase'
DEBBBBON_01552 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
DEBBBBON_01553 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DEBBBBON_01554 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
DEBBBBON_01555 2.9e-87 D nuclear chromosome segregation
DEBBBBON_01556 1.5e-127 ybbM S transport system, permease component
DEBBBBON_01557 1.2e-117 ybbL S abc transporter atp-binding protein
DEBBBBON_01558 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
DEBBBBON_01559 4.6e-140 cppA E CppA N-terminal
DEBBBBON_01560 5e-44 V CAAX protease self-immunity
DEBBBBON_01561 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DEBBBBON_01562 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DEBBBBON_01565 3e-47 spiA K sequence-specific DNA binding
DEBBBBON_01566 2.9e-28 blpT
DEBBBBON_01567 6.7e-98 blpT
DEBBBBON_01574 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
DEBBBBON_01577 7.4e-135 agrA KT phosphorelay signal transduction system
DEBBBBON_01578 4.2e-237 blpH 2.7.13.3 T protein histidine kinase activity
DEBBBBON_01580 7.3e-237 mesE M Transport protein ComB
DEBBBBON_01581 5.8e-166 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DEBBBBON_01582 3e-224 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DEBBBBON_01583 0.0 mdlB V abc transporter atp-binding protein
DEBBBBON_01584 0.0 mdlA V abc transporter atp-binding protein
DEBBBBON_01586 8.5e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
DEBBBBON_01587 4.3e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DEBBBBON_01588 7.1e-66 yutD J protein conserved in bacteria
DEBBBBON_01589 3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DEBBBBON_01591 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DEBBBBON_01592 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEBBBBON_01593 0.0 ftsI 3.4.16.4 M penicillin-binding protein
DEBBBBON_01594 4.3e-47 ftsL D cell division protein FtsL
DEBBBBON_01595 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DEBBBBON_01596 1.6e-65
DEBBBBON_01597 7.4e-27
DEBBBBON_01598 2.6e-30
DEBBBBON_01600 8.7e-33 yhaI J Protein of unknown function (DUF805)
DEBBBBON_01601 4.5e-18 D nuclear chromosome segregation
DEBBBBON_01602 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DEBBBBON_01603 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DEBBBBON_01604 2.2e-285 XK27_00765
DEBBBBON_01605 8.1e-134 ecsA_2 V abc transporter atp-binding protein
DEBBBBON_01606 5.2e-125 S Protein of unknown function (DUF554)
DEBBBBON_01607 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DEBBBBON_01608 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
DEBBBBON_01609 2.9e-56 liaI S membrane
DEBBBBON_01610 6.5e-68 KT response to antibiotic
DEBBBBON_01611 3.5e-17 KT response to antibiotic
DEBBBBON_01612 9.8e-80 yebC M Membrane
DEBBBBON_01613 1.1e-16 yebC M Membrane
DEBBBBON_01614 1.6e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
DEBBBBON_01615 2.3e-181 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
DEBBBBON_01616 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEBBBBON_01617 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEBBBBON_01618 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DEBBBBON_01619 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DEBBBBON_01620 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DEBBBBON_01621 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DEBBBBON_01623 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
DEBBBBON_01624 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
DEBBBBON_01625 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
DEBBBBON_01626 5.4e-291 scrB 3.2.1.26 GH32 G invertase
DEBBBBON_01627 7.5e-180 scrR K Transcriptional
DEBBBBON_01628 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEBBBBON_01629 3.4e-62 yqhY S protein conserved in bacteria
DEBBBBON_01630 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEBBBBON_01631 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
DEBBBBON_01632 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
DEBBBBON_01634 8e-44 V 'abc transporter, ATP-binding protein
DEBBBBON_01635 1e-58 V 'abc transporter, ATP-binding protein
DEBBBBON_01637 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DEBBBBON_01638 2e-169 corA P COG0598 Mg2 and Co2 transporters
DEBBBBON_01639 3.1e-124 XK27_01040 S Pfam PF06570
DEBBBBON_01641 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEBBBBON_01642 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DEBBBBON_01643 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
DEBBBBON_01644 8e-41 XK27_05745
DEBBBBON_01645 2.5e-230 mutY L A G-specific adenine glycosylase
DEBBBBON_01650 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEBBBBON_01651 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DEBBBBON_01652 6.7e-93 cvpA S toxin biosynthetic process
DEBBBBON_01653 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
DEBBBBON_01654 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEBBBBON_01655 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DEBBBBON_01656 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DEBBBBON_01657 8.8e-48 azlD E branched-chain amino acid
DEBBBBON_01658 3.8e-117 azlC E AzlC protein
DEBBBBON_01659 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEBBBBON_01660 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
DEBBBBON_01661 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
DEBBBBON_01662 2.5e-33 ykzG S Belongs to the UPF0356 family
DEBBBBON_01663 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEBBBBON_01664 2.7e-40 pscB M CHAP domain protein
DEBBBBON_01665 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
DEBBBBON_01666 8.5e-63 glnR K Transcriptional regulator
DEBBBBON_01667 1.3e-87 S Fusaric acid resistance protein-like
DEBBBBON_01668 1.1e-12
DEBBBBON_01669 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DEBBBBON_01670 1.9e-46 L transposase activity
DEBBBBON_01671 7.4e-23 L Transposase
DEBBBBON_01672 1.8e-56 L transposition
DEBBBBON_01673 9.1e-83 L Integrase core domain protein
DEBBBBON_01674 1e-102 L Transposase
DEBBBBON_01675 1.7e-111 L Transposase
DEBBBBON_01676 8.7e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DEBBBBON_01677 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEBBBBON_01678 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DEBBBBON_01679 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEBBBBON_01680 1.1e-142 purR 2.4.2.7 F operon repressor
DEBBBBON_01681 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
DEBBBBON_01682 6.9e-173 rmuC S RmuC domain protein
DEBBBBON_01683 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
DEBBBBON_01684 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DEBBBBON_01685 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DEBBBBON_01687 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DEBBBBON_01688 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DEBBBBON_01689 4.1e-144 tatD L Hydrolase, tatd
DEBBBBON_01690 2.5e-74 yccU S CoA-binding protein
DEBBBBON_01691 4.8e-51 trxA O Belongs to the thioredoxin family
DEBBBBON_01692 7.8e-143 S Macro domain protein
DEBBBBON_01693 3.1e-10 L thioesterase
DEBBBBON_01694 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
DEBBBBON_01696 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DEBBBBON_01697 5e-84 L Transposase
DEBBBBON_01698 1e-13 rpmH J Ribosomal protein L34
DEBBBBON_01699 2e-186 jag S RNA-binding protein
DEBBBBON_01700 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEBBBBON_01701 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DEBBBBON_01702 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
DEBBBBON_01703 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DEBBBBON_01704 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEBBBBON_01705 6.7e-81 amiA E transmembrane transport
DEBBBBON_01706 2e-41 amiA E transmembrane transport
DEBBBBON_01707 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
DEBBBBON_01708 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
DEBBBBON_01709 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DEBBBBON_01710 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEBBBBON_01711 9.2e-51 S Protein of unknown function (DUF3397)
DEBBBBON_01712 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DEBBBBON_01713 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
DEBBBBON_01714 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
DEBBBBON_01715 1.7e-221 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DEBBBBON_01716 5.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DEBBBBON_01717 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
DEBBBBON_01718 3e-78 XK27_09620 S reductase
DEBBBBON_01719 2.2e-60 XK27_09615 C reductase
DEBBBBON_01720 9.8e-140 XK27_09615 C reductase
DEBBBBON_01721 4.9e-54 fnt P Formate nitrite transporter
DEBBBBON_01722 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
DEBBBBON_01723 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DEBBBBON_01724 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DEBBBBON_01725 2.6e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
DEBBBBON_01726 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEBBBBON_01727 1.8e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DEBBBBON_01728 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DEBBBBON_01729 2.7e-48 S glycolate biosynthetic process
DEBBBBON_01730 3.4e-64 S phosphatase activity
DEBBBBON_01731 2e-157 rrmA 2.1.1.187 Q methyltransferase
DEBBBBON_01734 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DEBBBBON_01735 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DEBBBBON_01736 6.4e-37 yeeD O sulfur carrier activity
DEBBBBON_01737 1.3e-190 yeeE S Sulphur transport
DEBBBBON_01738 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DEBBBBON_01739 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DEBBBBON_01740 1.8e-09 S Domain of unknown function (DUF4651)
DEBBBBON_01741 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
DEBBBBON_01742 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DEBBBBON_01743 1.8e-111 S CAAX amino terminal protease family protein
DEBBBBON_01745 5e-67 V CAAX protease self-immunity
DEBBBBON_01746 1.4e-33 V CAAX protease self-immunity
DEBBBBON_01747 8.8e-27 lanR K sequence-specific DNA binding
DEBBBBON_01748 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEBBBBON_01749 5.9e-177 ytxK 2.1.1.72 L DNA methylase
DEBBBBON_01750 2e-12 comGF U Putative Competence protein ComGF
DEBBBBON_01751 1.5e-71 comGF U Competence protein ComGF
DEBBBBON_01752 1.1e-15 NU Type II secretory pathway pseudopilin
DEBBBBON_01753 1.8e-57 cglD NU Competence protein
DEBBBBON_01754 8.5e-43 comGC U Required for transformation and DNA binding
DEBBBBON_01755 1.1e-156 cglB U protein transport across the cell outer membrane
DEBBBBON_01756 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DEBBBBON_01757 2.9e-68 S cog cog4699
DEBBBBON_01758 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEBBBBON_01759 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEBBBBON_01760 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DEBBBBON_01761 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEBBBBON_01762 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DEBBBBON_01763 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
DEBBBBON_01764 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
DEBBBBON_01765 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DEBBBBON_01766 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
DEBBBBON_01767 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
DEBBBBON_01768 1.8e-57 asp S cog cog1302
DEBBBBON_01769 3.2e-226 norN V Mate efflux family protein
DEBBBBON_01770 6.4e-279 thrC 4.2.3.1 E Threonine synthase
DEBBBBON_01771 1.9e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DEBBBBON_01772 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
DEBBBBON_01773 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DEBBBBON_01774 3.4e-153 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DEBBBBON_01775 1.8e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
DEBBBBON_01776 0.0 pepO 3.4.24.71 O Peptidase family M13
DEBBBBON_01777 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DEBBBBON_01778 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DEBBBBON_01779 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
DEBBBBON_01780 1.4e-54 treB 2.7.1.201 G PTS System
DEBBBBON_01781 5.8e-21 treR K DNA-binding transcription factor activity
DEBBBBON_01782 8.6e-87 treR K trehalose operon
DEBBBBON_01783 7.4e-95 ywlG S Belongs to the UPF0340 family
DEBBBBON_01785 3.1e-87 L Phage integrase family
DEBBBBON_01786 5.7e-46 S Domain of unknown function (DUF4298)
DEBBBBON_01787 4.5e-61 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
DEBBBBON_01788 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
DEBBBBON_01791 9.1e-106 3.1.21.3 V Type I restriction modification DNA specificity domain
DEBBBBON_01792 1.2e-302 hsdM 2.1.1.72 V HsdM N-terminal domain
DEBBBBON_01793 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DEBBBBON_01794 2.4e-26
DEBBBBON_01795 2.8e-221 L Transposase
DEBBBBON_01796 1e-140 L DNA integration
DEBBBBON_01797 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
DEBBBBON_01799 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
DEBBBBON_01800 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
DEBBBBON_01801 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
DEBBBBON_01802 3.3e-09 L PFAM Integrase, catalytic core
DEBBBBON_01803 1.8e-111 L PFAM Integrase, catalytic core
DEBBBBON_01804 7.4e-62 rplQ J ribosomal protein l17
DEBBBBON_01805 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEBBBBON_01806 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEBBBBON_01807 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEBBBBON_01808 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DEBBBBON_01809 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEBBBBON_01810 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DEBBBBON_01811 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DEBBBBON_01812 4.4e-58 rplO J binds to the 23S rRNA
DEBBBBON_01813 2.5e-23 rpmD J ribosomal protein l30
DEBBBBON_01814 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEBBBBON_01815 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEBBBBON_01816 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEBBBBON_01817 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEBBBBON_01818 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEBBBBON_01819 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEBBBBON_01820 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEBBBBON_01821 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEBBBBON_01822 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEBBBBON_01823 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
DEBBBBON_01824 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEBBBBON_01825 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEBBBBON_01826 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEBBBBON_01827 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEBBBBON_01828 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEBBBBON_01829 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DEBBBBON_01830 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
DEBBBBON_01831 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEBBBBON_01832 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
DEBBBBON_01833 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DEBBBBON_01834 0.0 XK27_09800 I Acyltransferase
DEBBBBON_01835 1.7e-35 XK27_09805 S MORN repeat protein
DEBBBBON_01836 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEBBBBON_01837 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEBBBBON_01838 1.5e-89 adk 2.7.4.3 F topology modulation protein
DEBBBBON_01839 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DEBBBBON_01840 1.4e-127 Z012_04635 K sequence-specific DNA binding
DEBBBBON_01842 6.3e-16 C Radical SAM
DEBBBBON_01843 3.4e-191 C Radical SAM
DEBBBBON_01844 3.9e-287 V ABC transporter transmembrane region
DEBBBBON_01845 1.7e-90 K sequence-specific DNA binding
DEBBBBON_01846 1e-36 L Replication initiation factor
DEBBBBON_01847 1.4e-107 L Replication initiation factor
DEBBBBON_01848 1.9e-18 S Domain of unknown function (DUF3173)
DEBBBBON_01849 3.5e-216 int L Belongs to the 'phage' integrase family
DEBBBBON_01851 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
DEBBBBON_01852 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DEBBBBON_01853 2.8e-44 yrzL S Belongs to the UPF0297 family
DEBBBBON_01854 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEBBBBON_01855 5.5e-44 yrzB S Belongs to the UPF0473 family
DEBBBBON_01856 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
DEBBBBON_01857 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DEBBBBON_01858 7.5e-14
DEBBBBON_01859 2.6e-91 XK27_10930 K acetyltransferase
DEBBBBON_01860 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEBBBBON_01861 1.8e-147 yaaA S Belongs to the UPF0246 family
DEBBBBON_01862 9.9e-169 XK27_01785 S cog cog1284
DEBBBBON_01863 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DEBBBBON_01865 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
DEBBBBON_01866 5.7e-52 metE 2.1.1.14 E Methionine synthase
DEBBBBON_01867 7.6e-64 metE 2.1.1.14 E Methionine synthase
DEBBBBON_01868 9.2e-36 metE 2.1.1.14 E Methionine synthase
DEBBBBON_01869 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DEBBBBON_01870 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DEBBBBON_01872 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
DEBBBBON_01873 2.7e-95 S Hydrophobic domain protein
DEBBBBON_01875 3.7e-27 S Membrane
DEBBBBON_01876 3.1e-101
DEBBBBON_01877 1.8e-23 S Small integral membrane protein
DEBBBBON_01878 1.1e-71 M Protein conserved in bacteria
DEBBBBON_01879 4.9e-12 K CsbD-like
DEBBBBON_01880 3.4e-13 nudL L hydrolase
DEBBBBON_01881 4e-19 K negative regulation of transcription, DNA-templated
DEBBBBON_01882 1.7e-23 K negative regulation of transcription, DNA-templated
DEBBBBON_01884 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
DEBBBBON_01885 1.8e-88 S Putative adhesin
DEBBBBON_01886 3.9e-161 XK27_06930 V domain protein
DEBBBBON_01887 6.4e-96 XK27_06935 K transcriptional regulator
DEBBBBON_01888 5.5e-11 ypaA M Membrane
DEBBBBON_01889 2e-07
DEBBBBON_01890 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEBBBBON_01891 8.2e-48 veg S Biofilm formation stimulator VEG
DEBBBBON_01892 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DEBBBBON_01893 3.9e-70 rplI J binds to the 23S rRNA
DEBBBBON_01894 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DEBBBBON_01895 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DEBBBBON_01896 2.8e-76 F NUDIX domain
DEBBBBON_01897 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DEBBBBON_01898 0.0 S Bacterial membrane protein, YfhO
DEBBBBON_01899 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
DEBBBBON_01900 5.3e-85 lytE M LysM domain protein
DEBBBBON_01901 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEBBBBON_01902 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEBBBBON_01903 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEBBBBON_01904 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEBBBBON_01905 4.8e-138 ymfM S sequence-specific DNA binding
DEBBBBON_01906 1.4e-242 ymfH S Peptidase M16
DEBBBBON_01907 1.4e-234 ymfF S Peptidase M16
DEBBBBON_01908 6.2e-45 yaaA S S4 domain protein YaaA
DEBBBBON_01909 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEBBBBON_01910 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DEBBBBON_01911 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
DEBBBBON_01912 1.1e-153 yvjA S membrane
DEBBBBON_01913 6.7e-306 ybiT S abc transporter atp-binding protein
DEBBBBON_01914 0.0 XK27_10405 S Bacterial membrane protein YfhO
DEBBBBON_01918 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
DEBBBBON_01919 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DEBBBBON_01920 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
DEBBBBON_01921 8.5e-134 parB K Belongs to the ParB family
DEBBBBON_01922 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DEBBBBON_01923 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DEBBBBON_01924 1.1e-29 yyzM S Protein conserved in bacteria
DEBBBBON_01925 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DEBBBBON_01926 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DEBBBBON_01927 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DEBBBBON_01928 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
DEBBBBON_01929 2.7e-61 divIC D Septum formation initiator
DEBBBBON_01931 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
DEBBBBON_01932 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DEBBBBON_01933 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DEBBBBON_01934 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEBBBBON_01935 2.4e-164 L Transposase
DEBBBBON_01937 1e-141 3.1.21.4 L Recognizes the double-stranded unmethylated sequence GATC and cleaves before G-1
DEBBBBON_01938 6.1e-96 dam 2.1.1.72 L Site-specific DNA-methyltransferase (Adenine-specific)
DEBBBBON_01939 1.5e-132 L Replication protein
DEBBBBON_01940 5.2e-53
DEBBBBON_01948 1.6e-249 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)