ORF_ID e_value Gene_name EC_number CAZy COGs Description
NAAHDHDC_00011 5.3e-11
NAAHDHDC_00017 5.5e-139 mreC M Involved in formation and maintenance of cell shape
NAAHDHDC_00018 6.3e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NAAHDHDC_00019 1.7e-90 usp 3.5.1.28 CBM50 S CHAP domain
NAAHDHDC_00020 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NAAHDHDC_00021 2.9e-218 araT 2.6.1.1 E Aminotransferase
NAAHDHDC_00022 2.6e-143 recO L Involved in DNA repair and RecF pathway recombination
NAAHDHDC_00023 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NAAHDHDC_00024 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NAAHDHDC_00025 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NAAHDHDC_00026 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NAAHDHDC_00027 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NAAHDHDC_00028 1.8e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NAAHDHDC_00029 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NAAHDHDC_00030 2.3e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NAAHDHDC_00031 6.1e-79 L transposase activity
NAAHDHDC_00032 1.3e-49 L transposition
NAAHDHDC_00033 6.3e-34 L Integrase core domain protein
NAAHDHDC_00034 2.3e-161 S CHAP domain
NAAHDHDC_00035 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
NAAHDHDC_00036 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NAAHDHDC_00037 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NAAHDHDC_00038 9.2e-141 1.1.1.169 H Ketopantoate reductase
NAAHDHDC_00039 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NAAHDHDC_00040 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NAAHDHDC_00041 1.2e-09 L Transposase
NAAHDHDC_00042 7.8e-211 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NAAHDHDC_00043 8.3e-221 nodC 2.4.1.212 GT2 M Chitin synthase
NAAHDHDC_00046 1.3e-57 T Toxic component of a toxin-antitoxin (TA) module
NAAHDHDC_00048 8.2e-70 argR K Regulates arginine biosynthesis genes
NAAHDHDC_00049 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NAAHDHDC_00050 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NAAHDHDC_00051 7e-34 S Protein of unknown function (DUF3021)
NAAHDHDC_00052 1.2e-61 KT phosphorelay signal transduction system
NAAHDHDC_00054 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NAAHDHDC_00056 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NAAHDHDC_00057 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NAAHDHDC_00058 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
NAAHDHDC_00059 2.8e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NAAHDHDC_00060 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
NAAHDHDC_00065 2.6e-10
NAAHDHDC_00068 1.9e-07
NAAHDHDC_00073 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NAAHDHDC_00074 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NAAHDHDC_00075 2.1e-35 XK27_02060 S Transglycosylase associated protein
NAAHDHDC_00076 1.7e-54 badR K DNA-binding transcription factor activity
NAAHDHDC_00077 1e-96 S reductase
NAAHDHDC_00078 2.3e-31 L Integrase core domain protein
NAAHDHDC_00079 6.2e-36 L transposition
NAAHDHDC_00080 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
NAAHDHDC_00081 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NAAHDHDC_00084 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NAAHDHDC_00085 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NAAHDHDC_00086 1.1e-83 S Putative small multi-drug export protein
NAAHDHDC_00087 6.2e-76 ctsR K Belongs to the CtsR family
NAAHDHDC_00088 0.0 clpC O Belongs to the ClpA ClpB family
NAAHDHDC_00089 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NAAHDHDC_00090 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NAAHDHDC_00091 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NAAHDHDC_00092 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NAAHDHDC_00093 6.9e-144 S SseB protein N-terminal domain
NAAHDHDC_00094 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
NAAHDHDC_00095 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NAAHDHDC_00096 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NAAHDHDC_00099 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NAAHDHDC_00100 3.5e-91 yacP S RNA-binding protein containing a PIN domain
NAAHDHDC_00101 3.4e-155 degV S DegV family
NAAHDHDC_00102 1.8e-31 K helix-turn-helix
NAAHDHDC_00103 6.1e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NAAHDHDC_00104 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NAAHDHDC_00105 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NAAHDHDC_00106 1.5e-35 K sequence-specific DNA binding
NAAHDHDC_00108 0.0 S Lantibiotic dehydratase, C terminus
NAAHDHDC_00109 2.4e-231 spaC2 V Lanthionine synthetase C family protein
NAAHDHDC_00110 4.3e-183 EGP Major facilitator Superfamily
NAAHDHDC_00111 5.9e-24 3.6.4.12
NAAHDHDC_00112 5.9e-91 3.6.4.12 K Divergent AAA domain protein
NAAHDHDC_00113 7.4e-225 int L Belongs to the 'phage' integrase family
NAAHDHDC_00114 1.8e-38 S Helix-turn-helix domain
NAAHDHDC_00115 4.9e-173
NAAHDHDC_00117 3.4e-75 isp2 S pathogenesis
NAAHDHDC_00118 5.7e-91 tnp L Transposase
NAAHDHDC_00119 3.3e-225 capA M Bacterial capsule synthesis protein
NAAHDHDC_00120 3.6e-39 gcvR T UPF0237 protein
NAAHDHDC_00121 1.9e-242 XK27_08635 S UPF0210 protein
NAAHDHDC_00122 2.2e-38 ais G alpha-ribazole phosphatase activity
NAAHDHDC_00123 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NAAHDHDC_00124 1.3e-102 acmA 3.2.1.17 NU amidase activity
NAAHDHDC_00125 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NAAHDHDC_00126 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NAAHDHDC_00127 9.8e-298 dnaK O Heat shock 70 kDa protein
NAAHDHDC_00128 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NAAHDHDC_00129 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NAAHDHDC_00130 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NAAHDHDC_00131 1.7e-60 hmpT S membrane
NAAHDHDC_00132 9.9e-19 S Domain of unknown function (DUF4649)
NAAHDHDC_00133 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NAAHDHDC_00134 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NAAHDHDC_00135 6.5e-87
NAAHDHDC_00136 1.6e-77 sigH K DNA-templated transcription, initiation
NAAHDHDC_00137 3.5e-149 ykuT M mechanosensitive ion channel
NAAHDHDC_00138 7.1e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NAAHDHDC_00139 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NAAHDHDC_00140 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NAAHDHDC_00141 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
NAAHDHDC_00142 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NAAHDHDC_00143 2e-177 prmA J Ribosomal protein L11 methyltransferase
NAAHDHDC_00144 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NAAHDHDC_00145 1.4e-42 F nucleotide catabolic process
NAAHDHDC_00146 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NAAHDHDC_00147 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NAAHDHDC_00148 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NAAHDHDC_00149 1.8e-83 nrdI F Belongs to the NrdI family
NAAHDHDC_00150 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NAAHDHDC_00151 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NAAHDHDC_00152 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NAAHDHDC_00153 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NAAHDHDC_00154 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NAAHDHDC_00155 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NAAHDHDC_00156 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NAAHDHDC_00157 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NAAHDHDC_00158 5.3e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NAAHDHDC_00159 6.5e-202 yhjX P Major Facilitator
NAAHDHDC_00160 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NAAHDHDC_00161 5e-94 V VanZ like family
NAAHDHDC_00162 1e-123 glnQ E abc transporter atp-binding protein
NAAHDHDC_00163 5.8e-275 glnP P ABC transporter
NAAHDHDC_00164 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NAAHDHDC_00165 1.3e-134 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NAAHDHDC_00166 1.9e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
NAAHDHDC_00167 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NAAHDHDC_00168 1.4e-234 sufD O assembly protein SufD
NAAHDHDC_00169 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NAAHDHDC_00170 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
NAAHDHDC_00171 2.2e-273 sufB O assembly protein SufB
NAAHDHDC_00172 7e-10 oppA E ABC transporter substrate-binding protein
NAAHDHDC_00173 2e-138 oppA E ABC transporter substrate-binding protein
NAAHDHDC_00174 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NAAHDHDC_00175 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NAAHDHDC_00176 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NAAHDHDC_00177 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NAAHDHDC_00178 3e-27 oppD P Belongs to the ABC transporter superfamily
NAAHDHDC_00179 2.5e-32 oppD P Belongs to the ABC transporter superfamily
NAAHDHDC_00180 1.2e-62 oppD P Belongs to the ABC transporter superfamily
NAAHDHDC_00181 3.1e-43 oppD P Belongs to the ABC transporter superfamily
NAAHDHDC_00182 7.5e-62 oppF P Belongs to the ABC transporter superfamily
NAAHDHDC_00183 4.4e-62 oppF P Belongs to the ABC transporter superfamily
NAAHDHDC_00184 6.4e-23
NAAHDHDC_00185 2.1e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NAAHDHDC_00186 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NAAHDHDC_00187 1.9e-223 EGP Major facilitator Superfamily
NAAHDHDC_00188 3.1e-72 adcR K transcriptional
NAAHDHDC_00189 2.2e-136 adcC P ABC transporter, ATP-binding protein
NAAHDHDC_00190 1.6e-127 adcB P ABC transporter (Permease
NAAHDHDC_00191 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NAAHDHDC_00192 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
NAAHDHDC_00193 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
NAAHDHDC_00194 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NAAHDHDC_00195 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
NAAHDHDC_00196 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
NAAHDHDC_00197 1.9e-127 yeeN K transcriptional regulatory protein
NAAHDHDC_00198 9.8e-50 yajC U protein transport
NAAHDHDC_00199 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NAAHDHDC_00200 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
NAAHDHDC_00201 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NAAHDHDC_00202 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NAAHDHDC_00203 0.0 WQ51_06230 S ABC transporter substrate binding protein
NAAHDHDC_00204 5.2e-142 cmpC S abc transporter atp-binding protein
NAAHDHDC_00205 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NAAHDHDC_00206 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NAAHDHDC_00207 4.4e-37 L Transposase
NAAHDHDC_00208 6.4e-18 L transposase activity
NAAHDHDC_00211 4.7e-43
NAAHDHDC_00212 6.8e-56 S TM2 domain
NAAHDHDC_00213 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NAAHDHDC_00214 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NAAHDHDC_00215 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
NAAHDHDC_00216 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
NAAHDHDC_00217 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NAAHDHDC_00218 6e-55 cof Q phosphatase activity
NAAHDHDC_00219 6.2e-35 cof Q phosphatase activity
NAAHDHDC_00220 1.6e-137 glcR K transcriptional regulator (DeoR family)
NAAHDHDC_00221 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NAAHDHDC_00222 3.8e-40 K transcriptional
NAAHDHDC_00224 2.6e-76 S thiolester hydrolase activity
NAAHDHDC_00225 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
NAAHDHDC_00226 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NAAHDHDC_00227 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NAAHDHDC_00228 1.9e-77 yhaI L Membrane
NAAHDHDC_00229 5.1e-259 pepC 3.4.22.40 E aminopeptidase
NAAHDHDC_00230 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NAAHDHDC_00231 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NAAHDHDC_00232 3.1e-95 ypsA S Belongs to the UPF0398 family
NAAHDHDC_00233 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NAAHDHDC_00234 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NAAHDHDC_00235 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NAAHDHDC_00236 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NAAHDHDC_00237 2.5e-23
NAAHDHDC_00238 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NAAHDHDC_00239 7.3e-80 XK27_09675 K -acetyltransferase
NAAHDHDC_00240 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NAAHDHDC_00241 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NAAHDHDC_00242 5.2e-59 L Integrase core domain protein
NAAHDHDC_00243 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NAAHDHDC_00244 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NAAHDHDC_00245 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NAAHDHDC_00246 6.1e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NAAHDHDC_00247 8.8e-98 ybhL S Belongs to the BI1 family
NAAHDHDC_00250 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NAAHDHDC_00251 3.7e-91 K transcriptional regulator
NAAHDHDC_00252 7.6e-36 yneF S UPF0154 protein
NAAHDHDC_00253 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NAAHDHDC_00254 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NAAHDHDC_00255 3.5e-99 XK27_09740 S Phosphoesterase
NAAHDHDC_00256 7.8e-85 ykuL S CBS domain
NAAHDHDC_00257 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NAAHDHDC_00258 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NAAHDHDC_00259 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NAAHDHDC_00260 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NAAHDHDC_00261 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NAAHDHDC_00262 1.2e-258 trkH P Cation transport protein
NAAHDHDC_00263 1.5e-247 trkA P Potassium transporter peripheral membrane component
NAAHDHDC_00264 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NAAHDHDC_00265 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NAAHDHDC_00266 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NAAHDHDC_00267 5.6e-161 K sequence-specific DNA binding
NAAHDHDC_00268 1.2e-32 V protein secretion by the type I secretion system
NAAHDHDC_00269 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAAHDHDC_00270 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAAHDHDC_00271 1.6e-25 V protein secretion by the type I secretion system
NAAHDHDC_00272 1.8e-27 comA V protein secretion by the type I secretion system
NAAHDHDC_00273 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAAHDHDC_00274 3.7e-51 yhaI L Membrane
NAAHDHDC_00275 6.7e-36 S Domain of unknown function (DUF4173)
NAAHDHDC_00276 9.2e-132 S Domain of unknown function (DUF4173)
NAAHDHDC_00277 6.8e-95 ureI S AmiS/UreI family transporter
NAAHDHDC_00278 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NAAHDHDC_00279 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NAAHDHDC_00280 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NAAHDHDC_00281 6.6e-78 ureE O enzyme active site formation
NAAHDHDC_00282 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NAAHDHDC_00283 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NAAHDHDC_00284 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NAAHDHDC_00285 2.7e-177 cbiM P PDGLE domain
NAAHDHDC_00286 1.1e-136 P cobalt transport protein
NAAHDHDC_00287 1.6e-131 cbiO P ABC transporter
NAAHDHDC_00288 5.3e-153 ET amino acid transport
NAAHDHDC_00289 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAAHDHDC_00290 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
NAAHDHDC_00291 3.8e-205 EGP Transmembrane secretion effector
NAAHDHDC_00292 1.8e-153 ET amino acid transport
NAAHDHDC_00293 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
NAAHDHDC_00294 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NAAHDHDC_00295 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NAAHDHDC_00296 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NAAHDHDC_00297 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NAAHDHDC_00298 5.2e-98 metI P ABC transporter (Permease
NAAHDHDC_00299 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NAAHDHDC_00300 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NAAHDHDC_00301 8e-94 S UPF0397 protein
NAAHDHDC_00302 0.0 ykoD P abc transporter atp-binding protein
NAAHDHDC_00303 1.2e-146 cbiQ P cobalt transport
NAAHDHDC_00304 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NAAHDHDC_00305 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
NAAHDHDC_00306 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
NAAHDHDC_00307 1.2e-244 P COG0168 Trk-type K transport systems, membrane components
NAAHDHDC_00308 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NAAHDHDC_00309 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
NAAHDHDC_00310 3e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAAHDHDC_00311 2.8e-282 T PhoQ Sensor
NAAHDHDC_00312 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NAAHDHDC_00313 6.5e-218 dnaB L Replication initiation and membrane attachment
NAAHDHDC_00314 4.4e-166 dnaI L Primosomal protein DnaI
NAAHDHDC_00315 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NAAHDHDC_00317 1.2e-34
NAAHDHDC_00318 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
NAAHDHDC_00319 3e-27 L Integrase core domain protein
NAAHDHDC_00320 3.4e-50 L transposition
NAAHDHDC_00321 5.7e-23 L Transposase
NAAHDHDC_00322 7.8e-28 L transposase activity
NAAHDHDC_00323 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NAAHDHDC_00324 4.2e-62 manO S protein conserved in bacteria
NAAHDHDC_00325 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
NAAHDHDC_00326 2.3e-116 manM G pts system
NAAHDHDC_00327 1.1e-181 manL 2.7.1.191 G pts system
NAAHDHDC_00328 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NAAHDHDC_00329 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NAAHDHDC_00330 1.9e-248 pbuO S permease
NAAHDHDC_00331 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NAAHDHDC_00332 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
NAAHDHDC_00333 2.5e-220 brpA K Transcriptional
NAAHDHDC_00334 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
NAAHDHDC_00335 3.1e-212 nusA K Participates in both transcription termination and antitermination
NAAHDHDC_00336 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NAAHDHDC_00337 1.4e-41 ylxQ J ribosomal protein
NAAHDHDC_00338 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NAAHDHDC_00339 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NAAHDHDC_00340 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
NAAHDHDC_00341 1.5e-25 yvdD 3.2.2.10 S cytokinin biosynthetic process
NAAHDHDC_00342 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NAAHDHDC_00343 6.2e-85 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NAAHDHDC_00344 3.2e-49 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NAAHDHDC_00345 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NAAHDHDC_00346 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NAAHDHDC_00347 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NAAHDHDC_00348 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
NAAHDHDC_00349 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NAAHDHDC_00352 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NAAHDHDC_00353 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NAAHDHDC_00354 1.2e-74 ylbF S Belongs to the UPF0342 family
NAAHDHDC_00355 7.1e-46 ylbG S UPF0298 protein
NAAHDHDC_00356 4.5e-197 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NAAHDHDC_00357 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
NAAHDHDC_00358 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
NAAHDHDC_00359 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NAAHDHDC_00360 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NAAHDHDC_00361 6.8e-69 acuB S IMP dehydrogenase activity
NAAHDHDC_00362 8.9e-41 acuB S IMP dehydrogenase activity
NAAHDHDC_00363 3.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NAAHDHDC_00364 1.1e-110 yvyE 3.4.13.9 S YigZ family
NAAHDHDC_00365 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NAAHDHDC_00366 1.7e-122 comFC S Competence protein
NAAHDHDC_00367 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NAAHDHDC_00374 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
NAAHDHDC_00375 6.4e-108 S Domain of unknown function (DUF1803)
NAAHDHDC_00376 7.8e-102 ygaC J Belongs to the UPF0374 family
NAAHDHDC_00377 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
NAAHDHDC_00378 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NAAHDHDC_00379 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
NAAHDHDC_00380 2.6e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
NAAHDHDC_00381 1.9e-115 S Haloacid dehalogenase-like hydrolase
NAAHDHDC_00382 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NAAHDHDC_00383 4e-72 marR K Transcriptional regulator, MarR family
NAAHDHDC_00384 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NAAHDHDC_00385 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NAAHDHDC_00386 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NAAHDHDC_00387 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NAAHDHDC_00388 1.6e-126 IQ reductase
NAAHDHDC_00389 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NAAHDHDC_00390 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NAAHDHDC_00391 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NAAHDHDC_00392 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NAAHDHDC_00393 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NAAHDHDC_00394 1.1e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NAAHDHDC_00395 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NAAHDHDC_00396 1.1e-65 tnp L Transposase
NAAHDHDC_00397 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NAAHDHDC_00398 9.8e-176 gadC E Psort location CytoplasmicMembrane, score 10.00
NAAHDHDC_00399 4.7e-27 L Transposase and inactivated derivatives, TnpA family
NAAHDHDC_00400 3.4e-126 tnp L Transposase
NAAHDHDC_00402 8e-277 S Protein of unknown function (DUF3114)
NAAHDHDC_00403 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
NAAHDHDC_00404 7.7e-198 V (ABC) transporter
NAAHDHDC_00405 1.4e-74 C Arylsulfatase regulator (Fe-S oxidoreductase)
NAAHDHDC_00406 6.4e-85 C Arylsulfatase regulator (Fe-S oxidoreductase)
NAAHDHDC_00407 1.1e-113 K sequence-specific DNA binding
NAAHDHDC_00408 8.4e-155 L COG2801 Transposase and inactivated derivatives
NAAHDHDC_00409 6.6e-38 L transposase activity
NAAHDHDC_00410 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
NAAHDHDC_00411 1.8e-84 L Transposase
NAAHDHDC_00412 5.5e-122 fruR K transcriptional
NAAHDHDC_00413 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NAAHDHDC_00414 0.0 fruA 2.7.1.202 G phosphotransferase system
NAAHDHDC_00415 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NAAHDHDC_00416 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NAAHDHDC_00418 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NAAHDHDC_00419 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NAAHDHDC_00420 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NAAHDHDC_00421 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NAAHDHDC_00422 6.4e-29 2.3.1.128 K acetyltransferase
NAAHDHDC_00423 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NAAHDHDC_00424 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NAAHDHDC_00425 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NAAHDHDC_00426 2.6e-64 WQ51_03320 S cog cog4835
NAAHDHDC_00427 9.8e-91 XK27_08360 S EDD domain protein, DegV family
NAAHDHDC_00428 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NAAHDHDC_00429 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NAAHDHDC_00430 0.0 yfmR S abc transporter atp-binding protein
NAAHDHDC_00431 1.6e-24 U response to pH
NAAHDHDC_00432 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NAAHDHDC_00433 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NAAHDHDC_00434 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NAAHDHDC_00435 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NAAHDHDC_00436 1.9e-77 K DNA-binding transcription factor activity
NAAHDHDC_00437 0.0 lmrA1 V abc transporter atp-binding protein
NAAHDHDC_00438 0.0 lmrA2 V abc transporter atp-binding protein
NAAHDHDC_00439 5.4e-45 K Acetyltransferase (GNAT) family
NAAHDHDC_00440 3.2e-78 sptS 2.7.13.3 T Histidine kinase
NAAHDHDC_00441 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NAAHDHDC_00442 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NAAHDHDC_00443 5.3e-161 cvfB S Protein conserved in bacteria
NAAHDHDC_00444 7.4e-35 yozE S Belongs to the UPF0346 family
NAAHDHDC_00445 3.5e-124 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
NAAHDHDC_00446 2.3e-61 rlpA M LysM domain protein
NAAHDHDC_00447 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
NAAHDHDC_00451 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NAAHDHDC_00452 1.8e-164 K transcriptional regulator (lysR family)
NAAHDHDC_00453 1.4e-186 coiA 3.6.4.12 S Competence protein
NAAHDHDC_00454 0.0 pepF E oligoendopeptidase F
NAAHDHDC_00455 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
NAAHDHDC_00456 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NAAHDHDC_00457 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NAAHDHDC_00458 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NAAHDHDC_00459 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NAAHDHDC_00460 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
NAAHDHDC_00461 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NAAHDHDC_00462 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NAAHDHDC_00463 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NAAHDHDC_00464 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NAAHDHDC_00465 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NAAHDHDC_00466 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NAAHDHDC_00467 2.2e-130 yxkH G deacetylase
NAAHDHDC_00468 2.3e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NAAHDHDC_00469 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NAAHDHDC_00470 5.5e-153 rarD S Transporter
NAAHDHDC_00471 2.2e-15 T peptidase
NAAHDHDC_00472 8.9e-14 coiA 3.6.4.12 S Competence protein
NAAHDHDC_00473 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NAAHDHDC_00474 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NAAHDHDC_00475 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NAAHDHDC_00476 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NAAHDHDC_00477 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
NAAHDHDC_00478 3.3e-78 atpF C ATP synthase F(0) sector subunit b
NAAHDHDC_00479 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NAAHDHDC_00480 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NAAHDHDC_00481 7.4e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NAAHDHDC_00482 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NAAHDHDC_00483 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NAAHDHDC_00484 2.8e-230 ftsW D Belongs to the SEDS family
NAAHDHDC_00485 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NAAHDHDC_00486 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NAAHDHDC_00487 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NAAHDHDC_00488 1.9e-161 holB 2.7.7.7 L dna polymerase iii
NAAHDHDC_00489 2.1e-135 yaaT S stage 0 sporulation protein
NAAHDHDC_00490 9.5e-55 yabA L Involved in initiation control of chromosome replication
NAAHDHDC_00491 3.9e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NAAHDHDC_00492 7.5e-233 amt P Ammonium Transporter
NAAHDHDC_00493 1.1e-53 glnB K Belongs to the P(II) protein family
NAAHDHDC_00494 4.9e-106 mur1 NU mannosyl-glycoprotein
NAAHDHDC_00495 1.7e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NAAHDHDC_00496 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
NAAHDHDC_00497 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NAAHDHDC_00498 1.8e-53
NAAHDHDC_00499 7.5e-26
NAAHDHDC_00500 1.5e-59
NAAHDHDC_00501 6.1e-63 S membrane
NAAHDHDC_00502 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NAAHDHDC_00503 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NAAHDHDC_00504 4.5e-39 ynzC S UPF0291 protein
NAAHDHDC_00505 1.8e-254 cycA E permease
NAAHDHDC_00506 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
NAAHDHDC_00507 2.8e-24 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NAAHDHDC_00508 5.8e-71 pts33BCA G pts system
NAAHDHDC_00509 9e-96 pts33BCA G pts system
NAAHDHDC_00510 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
NAAHDHDC_00511 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NAAHDHDC_00516 1.4e-167 fhuR K transcriptional regulator (lysR family)
NAAHDHDC_00517 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NAAHDHDC_00518 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NAAHDHDC_00519 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NAAHDHDC_00520 4.9e-227 pyrP F uracil Permease
NAAHDHDC_00521 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NAAHDHDC_00522 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NAAHDHDC_00523 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NAAHDHDC_00524 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
NAAHDHDC_00525 4e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NAAHDHDC_00526 1.6e-33 V permease protein
NAAHDHDC_00527 1e-09 V permease protein
NAAHDHDC_00528 8.8e-21 V permease protein
NAAHDHDC_00529 1.7e-07 V efflux transmembrane transporter activity
NAAHDHDC_00530 1.1e-24 ytrF V efflux transmembrane transporter activity
NAAHDHDC_00531 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NAAHDHDC_00532 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NAAHDHDC_00534 0.0 mdlB V abc transporter atp-binding protein
NAAHDHDC_00535 0.0 lmrA V abc transporter atp-binding protein
NAAHDHDC_00536 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NAAHDHDC_00537 5.8e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NAAHDHDC_00538 6.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NAAHDHDC_00539 2.5e-132 rr02 KT response regulator
NAAHDHDC_00540 3.5e-202 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NAAHDHDC_00541 4.8e-168 V ABC transporter
NAAHDHDC_00542 5.4e-122 sagI S ABC-2 type transporter
NAAHDHDC_00543 4.5e-196 yceA S Belongs to the UPF0176 family
NAAHDHDC_00544 8e-28 XK27_00085 K Transcriptional
NAAHDHDC_00545 1.7e-23
NAAHDHDC_00546 1.2e-143 deoD_1 2.4.2.3 F Phosphorylase superfamily
NAAHDHDC_00547 2.8e-112 S VIT family
NAAHDHDC_00548 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NAAHDHDC_00549 2.4e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NAAHDHDC_00550 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
NAAHDHDC_00551 2e-47 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NAAHDHDC_00552 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NAAHDHDC_00553 8.8e-104 GBS0088 J protein conserved in bacteria
NAAHDHDC_00554 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NAAHDHDC_00555 1.5e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NAAHDHDC_00556 1.6e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
NAAHDHDC_00557 7.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NAAHDHDC_00558 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NAAHDHDC_00559 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NAAHDHDC_00560 2.5e-21
NAAHDHDC_00561 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NAAHDHDC_00563 3.5e-07 U protein secretion
NAAHDHDC_00564 2.5e-51 U protein secretion
NAAHDHDC_00565 7.4e-08 M Pilin isopeptide linkage domain protein
NAAHDHDC_00566 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NAAHDHDC_00567 1.5e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NAAHDHDC_00568 3.5e-49 XK27_13030
NAAHDHDC_00569 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NAAHDHDC_00570 8.3e-55 S hydrolase activity, acting on ester bonds
NAAHDHDC_00571 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NAAHDHDC_00572 6.8e-164 S Protein of unknown function (DUF3114)
NAAHDHDC_00573 1.2e-22 S Protein of unknown function (DUF3114)
NAAHDHDC_00574 1.5e-118 yqfA K protein, Hemolysin III
NAAHDHDC_00575 1e-25 K hmm pf08876
NAAHDHDC_00576 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NAAHDHDC_00577 1.7e-218 mvaS 2.3.3.10 I synthase
NAAHDHDC_00578 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NAAHDHDC_00579 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NAAHDHDC_00580 9.7e-22
NAAHDHDC_00581 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NAAHDHDC_00582 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NAAHDHDC_00583 1.5e-250 mmuP E amino acid
NAAHDHDC_00584 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NAAHDHDC_00585 1.4e-29 S Domain of unknown function (DUF1912)
NAAHDHDC_00586 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
NAAHDHDC_00587 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NAAHDHDC_00588 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NAAHDHDC_00589 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NAAHDHDC_00590 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
NAAHDHDC_00591 4.8e-16 S Protein of unknown function (DUF2969)
NAAHDHDC_00594 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
NAAHDHDC_00597 1.1e-44 S Domain of Unknown Function with PDB structure (DUF3862)
NAAHDHDC_00598 1.3e-29 S Domain of Unknown Function with PDB structure (DUF3862)
NAAHDHDC_00599 3.7e-70 M Pfam SNARE associated Golgi protein
NAAHDHDC_00600 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
NAAHDHDC_00601 1.6e-08 S oxidoreductase
NAAHDHDC_00602 9.3e-59 S oxidoreductase
NAAHDHDC_00603 9.7e-66 S oxidoreductase
NAAHDHDC_00604 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
NAAHDHDC_00605 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NAAHDHDC_00606 0.0 clpE O Belongs to the ClpA ClpB family
NAAHDHDC_00607 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NAAHDHDC_00608 1.3e-34 ykuJ S protein conserved in bacteria
NAAHDHDC_00609 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NAAHDHDC_00610 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAAHDHDC_00611 3.1e-78 feoA P FeoA domain protein
NAAHDHDC_00612 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NAAHDHDC_00613 1.5e-07
NAAHDHDC_00614 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NAAHDHDC_00615 2.2e-45 K sequence-specific DNA binding
NAAHDHDC_00616 1.5e-35 yugF I carboxylic ester hydrolase activity
NAAHDHDC_00617 7.5e-23 I Alpha/beta hydrolase family
NAAHDHDC_00618 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NAAHDHDC_00619 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NAAHDHDC_00620 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NAAHDHDC_00621 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NAAHDHDC_00622 5.8e-64 licT K transcriptional antiterminator
NAAHDHDC_00623 6.8e-53 licT K transcriptional antiterminator
NAAHDHDC_00624 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NAAHDHDC_00625 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NAAHDHDC_00626 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NAAHDHDC_00627 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NAAHDHDC_00628 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NAAHDHDC_00629 2.5e-220 mdtG EGP Major facilitator Superfamily
NAAHDHDC_00630 2e-33 secG U Preprotein translocase subunit SecG
NAAHDHDC_00631 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NAAHDHDC_00632 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NAAHDHDC_00633 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NAAHDHDC_00634 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NAAHDHDC_00635 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NAAHDHDC_00636 4.4e-183 ccpA K Catabolite control protein A
NAAHDHDC_00637 2.8e-28 yyaQ S YjbR
NAAHDHDC_00638 6.6e-101 yyaQ V Protein conserved in bacteria
NAAHDHDC_00639 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NAAHDHDC_00640 1e-78 yueI S Protein of unknown function (DUF1694)
NAAHDHDC_00641 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NAAHDHDC_00642 2e-25 WQ51_00785
NAAHDHDC_00643 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NAAHDHDC_00644 2e-219 ywbD 2.1.1.191 J Methyltransferase
NAAHDHDC_00645 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NAAHDHDC_00646 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NAAHDHDC_00647 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NAAHDHDC_00648 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NAAHDHDC_00649 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NAAHDHDC_00650 3.2e-53 yheA S Belongs to the UPF0342 family
NAAHDHDC_00651 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NAAHDHDC_00652 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NAAHDHDC_00653 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NAAHDHDC_00654 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
NAAHDHDC_00655 6.4e-252 msrR K Transcriptional regulator
NAAHDHDC_00656 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
NAAHDHDC_00657 2.4e-203 I acyl-CoA dehydrogenase
NAAHDHDC_00658 4.5e-97 mip S hydroperoxide reductase activity
NAAHDHDC_00659 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NAAHDHDC_00660 8.9e-20
NAAHDHDC_00661 3.2e-46
NAAHDHDC_00662 1e-31 K Cro/C1-type HTH DNA-binding domain
NAAHDHDC_00663 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
NAAHDHDC_00664 9.7e-34 estA E GDSL-like Lipase/Acylhydrolase
NAAHDHDC_00665 1.1e-94
NAAHDHDC_00666 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NAAHDHDC_00667 4.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAAHDHDC_00668 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAAHDHDC_00669 5.9e-194 S CRISPR-associated protein Csn2 subfamily St
NAAHDHDC_00670 2.7e-146 ycgQ S TIGR03943 family
NAAHDHDC_00671 4.6e-155 XK27_03015 S permease
NAAHDHDC_00673 0.0 yhgF K Transcriptional accessory protein
NAAHDHDC_00674 9.9e-42 pspC KT PspC domain
NAAHDHDC_00675 2e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NAAHDHDC_00676 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NAAHDHDC_00678 5.5e-69 ytxH S General stress protein
NAAHDHDC_00680 2e-177 yegQ O Peptidase U32
NAAHDHDC_00681 3.4e-252 yegQ O Peptidase U32
NAAHDHDC_00682 8.1e-46 S CHY zinc finger
NAAHDHDC_00683 8.4e-88 bioY S biotin synthase
NAAHDHDC_00685 1.1e-33 XK27_12190 S protein conserved in bacteria
NAAHDHDC_00686 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
NAAHDHDC_00687 4.8e-11
NAAHDHDC_00688 6e-209 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
NAAHDHDC_00689 4.1e-225 mutH L DNA mismatch repair enzyme MutH
NAAHDHDC_00690 5.2e-29 S SIR2-like domain
NAAHDHDC_00691 1.2e-33 S SIR2-like domain
NAAHDHDC_00692 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NAAHDHDC_00693 6.4e-158 M LysM domain
NAAHDHDC_00694 7.6e-16
NAAHDHDC_00695 2.3e-175 S hydrolase
NAAHDHDC_00696 5.6e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
NAAHDHDC_00697 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NAAHDHDC_00698 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
NAAHDHDC_00699 2.7e-27 P Hemerythrin HHE cation binding domain protein
NAAHDHDC_00700 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NAAHDHDC_00701 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
NAAHDHDC_00702 3.9e-290 hsdM 2.1.1.72 V N-6 DNA Methylase
NAAHDHDC_00703 2.2e-147 3.1.21.3 V type I restriction modification DNA specificity domain
NAAHDHDC_00705 2.5e-44
NAAHDHDC_00706 3e-38
NAAHDHDC_00707 2.3e-171 spd F DNA RNA non-specific endonuclease
NAAHDHDC_00708 1.5e-92 lemA S LemA family
NAAHDHDC_00709 1.8e-135 htpX O Belongs to the peptidase M48B family
NAAHDHDC_00710 4.2e-75 S Psort location CytoplasmicMembrane, score
NAAHDHDC_00711 6.2e-56 S Domain of unknown function (DUF4430)
NAAHDHDC_00712 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NAAHDHDC_00713 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
NAAHDHDC_00714 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NAAHDHDC_00715 1.9e-23 L Transposase
NAAHDHDC_00716 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NAAHDHDC_00717 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NAAHDHDC_00718 3.5e-91 dps P Belongs to the Dps family
NAAHDHDC_00719 1.1e-80 perR P Belongs to the Fur family
NAAHDHDC_00720 8.4e-28 yqgQ S protein conserved in bacteria
NAAHDHDC_00721 2.2e-179 glk 2.7.1.2 G Glucokinase
NAAHDHDC_00722 0.0 typA T GTP-binding protein TypA
NAAHDHDC_00724 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NAAHDHDC_00725 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NAAHDHDC_00726 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NAAHDHDC_00727 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NAAHDHDC_00728 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NAAHDHDC_00729 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NAAHDHDC_00730 6.8e-96 sepF D cell septum assembly
NAAHDHDC_00731 2.6e-34 yggT D integral membrane protein
NAAHDHDC_00732 4.2e-144 ylmH T S4 RNA-binding domain
NAAHDHDC_00733 1.8e-135 divIVA D Cell division protein DivIVA
NAAHDHDC_00734 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NAAHDHDC_00735 5.5e-30
NAAHDHDC_00736 8.4e-10
NAAHDHDC_00737 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
NAAHDHDC_00738 2e-45 rpmE2 J 50S ribosomal protein L31
NAAHDHDC_00739 8.3e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NAAHDHDC_00740 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NAAHDHDC_00741 8.9e-155 gst O Glutathione S-transferase
NAAHDHDC_00742 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NAAHDHDC_00743 4.5e-111 tdk 2.7.1.21 F thymidine kinase
NAAHDHDC_00744 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NAAHDHDC_00745 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NAAHDHDC_00746 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NAAHDHDC_00747 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NAAHDHDC_00748 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
NAAHDHDC_00749 8e-100 pvaA M lytic transglycosylase activity
NAAHDHDC_00750 0.0 yfiB1 V abc transporter atp-binding protein
NAAHDHDC_00751 0.0 XK27_10035 V abc transporter atp-binding protein
NAAHDHDC_00752 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
NAAHDHDC_00753 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAAHDHDC_00754 3.9e-237 dltB M Membrane protein involved in D-alanine export
NAAHDHDC_00755 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NAAHDHDC_00756 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NAAHDHDC_00757 9.6e-32 L transposition
NAAHDHDC_00758 6.5e-54 L transposition
NAAHDHDC_00759 7.7e-19 L transposase activity
NAAHDHDC_00760 2.5e-40 L Transposase
NAAHDHDC_00761 0.0 3.6.3.8 P cation transport ATPase
NAAHDHDC_00762 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NAAHDHDC_00763 1.9e-105 V Abi-like protein
NAAHDHDC_00765 2.3e-12
NAAHDHDC_00767 2e-296 S DNA primase
NAAHDHDC_00768 3e-164 KL Phage plasmid primase P4 family
NAAHDHDC_00769 2.4e-22
NAAHDHDC_00770 1.2e-14
NAAHDHDC_00774 1.8e-19 K Cro/C1-type HTH DNA-binding domain
NAAHDHDC_00775 1e-21 xre K transcriptional
NAAHDHDC_00776 6.9e-220 sip L Belongs to the 'phage' integrase family
NAAHDHDC_00778 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NAAHDHDC_00779 7.3e-166 metF 1.5.1.20 E reductase
NAAHDHDC_00780 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NAAHDHDC_00781 1.7e-94 panT S ECF transporter, substrate-specific component
NAAHDHDC_00782 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NAAHDHDC_00783 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NAAHDHDC_00784 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NAAHDHDC_00785 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAAHDHDC_00786 2.8e-40 T PhoQ Sensor
NAAHDHDC_00787 1.7e-43 T PhoQ Sensor
NAAHDHDC_00788 5.8e-79 T PhoQ Sensor
NAAHDHDC_00789 2.1e-30 rpsT J rRNA binding
NAAHDHDC_00790 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
NAAHDHDC_00791 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
NAAHDHDC_00792 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NAAHDHDC_00793 6e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NAAHDHDC_00794 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NAAHDHDC_00795 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NAAHDHDC_00796 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NAAHDHDC_00797 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NAAHDHDC_00798 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NAAHDHDC_00799 4e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
NAAHDHDC_00800 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
NAAHDHDC_00801 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NAAHDHDC_00802 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NAAHDHDC_00803 3.1e-81 ypmB S Protein conserved in bacteria
NAAHDHDC_00804 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NAAHDHDC_00805 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NAAHDHDC_00806 1.5e-07
NAAHDHDC_00807 1.1e-12
NAAHDHDC_00808 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NAAHDHDC_00809 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NAAHDHDC_00810 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NAAHDHDC_00811 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NAAHDHDC_00812 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NAAHDHDC_00813 4.2e-18 D nuclear chromosome segregation
NAAHDHDC_00814 1.5e-135 yejC S cyclic nucleotide-binding protein
NAAHDHDC_00815 1.2e-163 rapZ S Displays ATPase and GTPase activities
NAAHDHDC_00816 1.8e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NAAHDHDC_00817 8.7e-162 whiA K May be required for sporulation
NAAHDHDC_00818 8e-90 pepD E Dipeptidase
NAAHDHDC_00819 5.8e-41 pepD E dipeptidase activity
NAAHDHDC_00820 5.4e-32 cspD K Cold shock protein domain
NAAHDHDC_00821 9.4e-43 K Cold-Shock Protein
NAAHDHDC_00822 2.8e-221 L Transposase
NAAHDHDC_00823 0.0 copB 3.6.3.4 P P-type ATPase
NAAHDHDC_00824 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NAAHDHDC_00825 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NAAHDHDC_00826 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
NAAHDHDC_00827 4.8e-157 glcU U Glucose uptake
NAAHDHDC_00828 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
NAAHDHDC_00829 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
NAAHDHDC_00830 2.2e-101 XK27_10720 D peptidase activity
NAAHDHDC_00831 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
NAAHDHDC_00832 1.7e-08
NAAHDHDC_00834 1.2e-172 yeiH S Membrane
NAAHDHDC_00835 5.5e-119 mur1 NU muramidase
NAAHDHDC_00836 1.9e-83 L transposition
NAAHDHDC_00837 2.6e-166 cpsY K Transcriptional regulator
NAAHDHDC_00838 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NAAHDHDC_00839 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
NAAHDHDC_00840 2e-104 artQ P ABC transporter (Permease
NAAHDHDC_00841 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAAHDHDC_00842 1.1e-158 aatB ET ABC transporter substrate-binding protein
NAAHDHDC_00843 3.5e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAAHDHDC_00844 2.5e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAAHDHDC_00845 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
NAAHDHDC_00846 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
NAAHDHDC_00847 9.3e-20 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
NAAHDHDC_00848 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NAAHDHDC_00849 4.5e-126 gntR1 K transcriptional
NAAHDHDC_00850 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NAAHDHDC_00851 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NAAHDHDC_00852 4.1e-87 niaX
NAAHDHDC_00853 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
NAAHDHDC_00854 6.9e-127 K DNA-binding helix-turn-helix protein
NAAHDHDC_00855 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NAAHDHDC_00856 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NAAHDHDC_00857 4.1e-167 GK ROK family
NAAHDHDC_00858 8.3e-159 dprA LU DNA protecting protein DprA
NAAHDHDC_00859 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NAAHDHDC_00860 1.4e-150 S TraX protein
NAAHDHDC_00861 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAAHDHDC_00862 2.4e-251 T PhoQ Sensor
NAAHDHDC_00863 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NAAHDHDC_00864 1.1e-152 XK27_05470 E Methionine synthase
NAAHDHDC_00865 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NAAHDHDC_00866 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NAAHDHDC_00867 1.8e-51 IQ Acetoin reductase
NAAHDHDC_00868 6.6e-19 IQ Acetoin reductase
NAAHDHDC_00869 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NAAHDHDC_00870 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAAHDHDC_00873 1.3e-212 pqqE C radical SAM domain protein
NAAHDHDC_00874 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
NAAHDHDC_00875 6.6e-61 EGP Major facilitator Superfamily
NAAHDHDC_00876 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NAAHDHDC_00877 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NAAHDHDC_00878 2.9e-196 L Transposase
NAAHDHDC_00879 7.6e-134 5.1.3.2 GM Psort location CytoplasmicMembrane, score
NAAHDHDC_00880 4.1e-143
NAAHDHDC_00881 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
NAAHDHDC_00882 7.6e-160 pelF GT4 M Domain of unknown function (DUF3492)
NAAHDHDC_00883 1.9e-109 pelF GT4 M Domain of unknown function (DUF3492)
NAAHDHDC_00884 6.8e-185 pelG M Putative exopolysaccharide Exporter (EPS-E)
NAAHDHDC_00885 1.5e-211 cotH M CotH kinase protein
NAAHDHDC_00886 8.4e-53 G Domain of unknown function (DUF4832)
NAAHDHDC_00887 4.9e-21 G Domain of unknown function (DUF4832)
NAAHDHDC_00888 3.7e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NAAHDHDC_00890 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NAAHDHDC_00891 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
NAAHDHDC_00892 1.4e-124 endA F DNA RNA non-specific endonuclease
NAAHDHDC_00893 4.2e-110 tcyB_2 P ABC transporter (permease)
NAAHDHDC_00894 8e-115 gltJ P ABC transporter (Permease
NAAHDHDC_00895 3.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NAAHDHDC_00896 1e-139 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAAHDHDC_00897 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAAHDHDC_00898 1.5e-247 vicK 2.7.13.3 T Histidine kinase
NAAHDHDC_00899 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NAAHDHDC_00900 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NAAHDHDC_00901 9.2e-147 yidA S hydrolases of the HAD superfamily
NAAHDHDC_00902 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
NAAHDHDC_00903 2.6e-67 ywiB S Domain of unknown function (DUF1934)
NAAHDHDC_00904 0.0 pacL 3.6.3.8 P cation transport ATPase
NAAHDHDC_00905 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NAAHDHDC_00906 4.3e-180 yjjH S Calcineurin-like phosphoesterase
NAAHDHDC_00907 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NAAHDHDC_00908 1.8e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NAAHDHDC_00909 2.5e-124 ftsE D cell division ATP-binding protein FtsE
NAAHDHDC_00910 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NAAHDHDC_00911 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NAAHDHDC_00912 1.1e-175 yubA S permease
NAAHDHDC_00913 4.9e-224 G COG0457 FOG TPR repeat
NAAHDHDC_00914 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NAAHDHDC_00915 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NAAHDHDC_00916 2.9e-90 ebsA S Family of unknown function (DUF5322)
NAAHDHDC_00917 3.9e-15 M LysM domain
NAAHDHDC_00918 2.8e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NAAHDHDC_00919 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NAAHDHDC_00920 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NAAHDHDC_00921 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NAAHDHDC_00922 9.1e-10 L COG1943 Transposase and inactivated derivatives
NAAHDHDC_00923 6.9e-86 XK27_03610 K Gnat family
NAAHDHDC_00924 3.2e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NAAHDHDC_00925 2.4e-275 pepV 3.5.1.18 E Dipeptidase
NAAHDHDC_00926 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
NAAHDHDC_00927 4e-21 V Glucan-binding protein C
NAAHDHDC_00929 6.6e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NAAHDHDC_00930 9.3e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NAAHDHDC_00931 7.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NAAHDHDC_00932 3.8e-42 clcA_2 P chloride channel
NAAHDHDC_00933 3.6e-40 clcA_2 P chloride
NAAHDHDC_00934 2.5e-43 yfeJ 6.3.5.2 F glutamine amidotransferase
NAAHDHDC_00935 1.7e-48 yfeJ 6.3.5.2 F glutamine amidotransferase
NAAHDHDC_00936 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NAAHDHDC_00937 3.8e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NAAHDHDC_00938 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NAAHDHDC_00939 2.6e-105 cps4C M biosynthesis protein
NAAHDHDC_00940 5.3e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
NAAHDHDC_00941 5.7e-250 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NAAHDHDC_00942 8.5e-23 rgpAc GT4 M group 1 family protein
NAAHDHDC_00943 1.7e-27 tnp L DDE domain
NAAHDHDC_00944 2.2e-22 L Transposase
NAAHDHDC_00945 3e-139 L Integrase core domain
NAAHDHDC_00946 6.9e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
NAAHDHDC_00947 2.4e-93 L Transposase
NAAHDHDC_00948 3.1e-110 L Transposase
NAAHDHDC_00949 1.4e-235 cps1C S Polysaccharide biosynthesis protein
NAAHDHDC_00950 8.1e-52 tnp L DDE domain
NAAHDHDC_00951 2.4e-30 tra981A L Integrase core domain
NAAHDHDC_00952 4e-60 L COG2801 Transposase and inactivated derivatives
NAAHDHDC_00953 3.3e-37 L transposase activity
NAAHDHDC_00954 1.2e-70 rfbP 2.7.8.6 M Bacterial sugar transferase
NAAHDHDC_00955 1.4e-72 cpsF M Oligosaccharide biosynthesis protein Alg14 like
NAAHDHDC_00956 1.9e-41 pssE S Glycosyltransferase family 28 C-terminal domain
NAAHDHDC_00957 1.1e-71 M Glycosyltransferase sugar-binding region containing DXD motif
NAAHDHDC_00958 3e-15
NAAHDHDC_00959 6.4e-33 cpsJ S Glycosyltransferase like family 2
NAAHDHDC_00960 6.4e-104 V ABC transporter (Permease
NAAHDHDC_00961 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NAAHDHDC_00962 1.6e-10
NAAHDHDC_00963 1.2e-97 K Transcriptional regulator, TetR family
NAAHDHDC_00964 1.2e-158 czcD P cation diffusion facilitator family transporter
NAAHDHDC_00965 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NAAHDHDC_00966 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NAAHDHDC_00967 6e-08 S Hydrolases of the alpha beta superfamily
NAAHDHDC_00968 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
NAAHDHDC_00969 3.8e-78 S Alpha/beta hydrolase of unknown function (DUF915)
NAAHDHDC_00972 2.6e-143 2.4.2.3 F Phosphorylase superfamily
NAAHDHDC_00973 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NAAHDHDC_00974 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
NAAHDHDC_00975 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
NAAHDHDC_00976 6.6e-73 dinF V Mate efflux family protein
NAAHDHDC_00977 4.8e-41 dinF V Mate efflux family protein
NAAHDHDC_00979 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NAAHDHDC_00980 3.7e-190
NAAHDHDC_00981 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
NAAHDHDC_00982 3.5e-28 3.4.13.21 I Protein conserved in bacteria
NAAHDHDC_00984 5.7e-118 S TraX protein
NAAHDHDC_00985 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NAAHDHDC_00986 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NAAHDHDC_00987 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NAAHDHDC_00988 4.7e-143 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAAHDHDC_00989 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAAHDHDC_00990 6.8e-133 cas6 S Pfam:DUF2276
NAAHDHDC_00991 0.0 csm1 S CRISPR-associated protein Csm1 family
NAAHDHDC_00992 5.6e-62 csm2 L Pfam:DUF310
NAAHDHDC_00993 1.1e-116 csm3 L RAMP superfamily
NAAHDHDC_00994 5.8e-166 csm4 L CRISPR-associated RAMP protein, Csm4 family
NAAHDHDC_00995 4.4e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
NAAHDHDC_00996 2.1e-14 csm6 S Psort location Cytoplasmic, score
NAAHDHDC_00997 5.2e-74 csm6 S Psort location Cytoplasmic, score
NAAHDHDC_00998 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NAAHDHDC_00999 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NAAHDHDC_01000 1.2e-63 nylA 3.5.1.4 J Belongs to the amidase family
NAAHDHDC_01002 2.5e-267 dtpT E transporter
NAAHDHDC_01003 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
NAAHDHDC_01004 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
NAAHDHDC_01005 1.8e-67 yecS P ABC transporter (Permease
NAAHDHDC_01007 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NAAHDHDC_01008 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
NAAHDHDC_01009 5.4e-104 yfiF3 K sequence-specific DNA binding
NAAHDHDC_01010 1.9e-147 L Transposase
NAAHDHDC_01011 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NAAHDHDC_01012 1.8e-240 agcS E (Alanine) symporter
NAAHDHDC_01013 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NAAHDHDC_01014 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
NAAHDHDC_01015 1.8e-59 Q phosphatase activity
NAAHDHDC_01016 9.3e-62 S haloacid dehalogenase-like hydrolase
NAAHDHDC_01017 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NAAHDHDC_01018 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NAAHDHDC_01019 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
NAAHDHDC_01020 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
NAAHDHDC_01021 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NAAHDHDC_01022 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NAAHDHDC_01023 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NAAHDHDC_01024 1.9e-43 yktA S Belongs to the UPF0223 family
NAAHDHDC_01025 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NAAHDHDC_01026 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NAAHDHDC_01027 3.3e-158 pstS P phosphate
NAAHDHDC_01028 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
NAAHDHDC_01029 2e-155 pstA P phosphate transport system permease
NAAHDHDC_01030 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NAAHDHDC_01031 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NAAHDHDC_01032 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
NAAHDHDC_01033 0.0 pepN 3.4.11.2 E aminopeptidase
NAAHDHDC_01034 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NAAHDHDC_01035 1.3e-187 lplA 6.3.1.20 H Lipoate-protein ligase
NAAHDHDC_01036 1.1e-17
NAAHDHDC_01037 3.7e-09
NAAHDHDC_01038 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NAAHDHDC_01039 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NAAHDHDC_01040 2.3e-23 L Transposase
NAAHDHDC_01041 4.6e-25 tatA U protein secretion
NAAHDHDC_01042 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NAAHDHDC_01043 1.1e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NAAHDHDC_01044 5.6e-233 ycdB P peroxidase
NAAHDHDC_01045 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
NAAHDHDC_01046 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01047 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01048 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01049 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01050 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01051 1.9e-37 3.5.1.28 NU amidase activity
NAAHDHDC_01052 8.5e-266 3.5.1.28 NU amidase activity
NAAHDHDC_01053 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NAAHDHDC_01054 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NAAHDHDC_01055 0.0 lpdA 1.8.1.4 C Dehydrogenase
NAAHDHDC_01056 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NAAHDHDC_01057 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NAAHDHDC_01058 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NAAHDHDC_01059 5e-38 P membrane protein (DUF2207)
NAAHDHDC_01060 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
NAAHDHDC_01061 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NAAHDHDC_01062 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NAAHDHDC_01063 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NAAHDHDC_01064 1.2e-157 rssA S Phospholipase, patatin family
NAAHDHDC_01065 3.9e-78 estA E GDSL-like protein
NAAHDHDC_01066 2.6e-15 estA E Lysophospholipase L1 and related esterases
NAAHDHDC_01067 3.7e-293 S unusual protein kinase
NAAHDHDC_01068 4.9e-39 S granule-associated protein
NAAHDHDC_01069 7.9e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NAAHDHDC_01070 5.8e-28 bglH 3.2.1.86 GT1 G beta-glucosidase activity
NAAHDHDC_01071 1.3e-199 S hmm pf01594
NAAHDHDC_01072 1.6e-44 G alpha-ribazole phosphatase activity
NAAHDHDC_01073 2e-33 G Belongs to the phosphoglycerate mutase family
NAAHDHDC_01074 1.1e-25 G Belongs to the phosphoglycerate mutase family
NAAHDHDC_01075 8.8e-66 pgm G Belongs to the phosphoglycerate mutase family
NAAHDHDC_01076 1.7e-80 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NAAHDHDC_01077 4.9e-94 V VanZ like family
NAAHDHDC_01078 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NAAHDHDC_01079 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NAAHDHDC_01080 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NAAHDHDC_01081 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NAAHDHDC_01082 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NAAHDHDC_01083 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
NAAHDHDC_01085 7.7e-35
NAAHDHDC_01088 7.8e-202 S Phage integrase family
NAAHDHDC_01090 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NAAHDHDC_01091 4.3e-133 XK27_05110 P chloride
NAAHDHDC_01092 1.2e-61 XK27_05110 P chloride
NAAHDHDC_01093 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NAAHDHDC_01094 1.3e-282 clcA P Chloride transporter, ClC family
NAAHDHDC_01095 6.7e-75 fld C Flavodoxin
NAAHDHDC_01097 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
NAAHDHDC_01098 3.5e-151 estA CE1 S Putative esterase
NAAHDHDC_01099 1e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NAAHDHDC_01100 1.2e-135 XK27_08845 S abc transporter atp-binding protein
NAAHDHDC_01101 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NAAHDHDC_01102 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
NAAHDHDC_01103 3.2e-17 S Domain of unknown function (DUF4649)
NAAHDHDC_01105 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
NAAHDHDC_01106 1.1e-22 Q the current gene model (or a revised gene model) may contain a frame shift
NAAHDHDC_01107 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
NAAHDHDC_01108 1.3e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NAAHDHDC_01109 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NAAHDHDC_01110 0.0 dnaE 2.7.7.7 L DNA polymerase
NAAHDHDC_01111 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
NAAHDHDC_01112 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NAAHDHDC_01113 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NAAHDHDC_01114 2.5e-43 ysdA L Membrane
NAAHDHDC_01115 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NAAHDHDC_01116 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NAAHDHDC_01117 3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NAAHDHDC_01118 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NAAHDHDC_01120 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NAAHDHDC_01121 1.7e-83 ypmS S Protein conserved in bacteria
NAAHDHDC_01122 6e-144 ypmR E lipolytic protein G-D-S-L family
NAAHDHDC_01123 1e-148 DegV S DegV family
NAAHDHDC_01124 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
NAAHDHDC_01125 1.8e-72 argR K Regulates arginine biosynthesis genes
NAAHDHDC_01126 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NAAHDHDC_01127 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NAAHDHDC_01128 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
NAAHDHDC_01129 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NAAHDHDC_01132 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NAAHDHDC_01133 2.9e-125 dnaD
NAAHDHDC_01134 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NAAHDHDC_01135 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NAAHDHDC_01136 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NAAHDHDC_01137 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NAAHDHDC_01138 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NAAHDHDC_01139 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NAAHDHDC_01140 7.1e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NAAHDHDC_01141 1.6e-239 rodA D Belongs to the SEDS family
NAAHDHDC_01142 4.5e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NAAHDHDC_01143 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NAAHDHDC_01144 1.9e-133 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NAAHDHDC_01145 5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NAAHDHDC_01146 1.2e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NAAHDHDC_01147 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NAAHDHDC_01148 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NAAHDHDC_01149 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NAAHDHDC_01150 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NAAHDHDC_01151 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NAAHDHDC_01153 4.2e-86 L Integrase core domain protein
NAAHDHDC_01154 1.1e-53 L transposition
NAAHDHDC_01155 8.2e-22 L Transposase
NAAHDHDC_01156 5.2e-36 L transposase activity
NAAHDHDC_01157 1.3e-22 XK27_08085
NAAHDHDC_01158 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NAAHDHDC_01159 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NAAHDHDC_01160 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NAAHDHDC_01161 1.1e-121 ylfI S tigr01906
NAAHDHDC_01162 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NAAHDHDC_01163 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
NAAHDHDC_01164 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NAAHDHDC_01167 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NAAHDHDC_01168 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NAAHDHDC_01169 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NAAHDHDC_01170 1.1e-206 yurR 1.4.5.1 E oxidoreductase
NAAHDHDC_01171 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
NAAHDHDC_01172 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NAAHDHDC_01173 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NAAHDHDC_01174 1.7e-70 gtrA S GtrA-like protein
NAAHDHDC_01175 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NAAHDHDC_01176 6e-169 ybbR S Protein conserved in bacteria
NAAHDHDC_01177 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NAAHDHDC_01178 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NAAHDHDC_01179 8.7e-150 cobQ S glutamine amidotransferase
NAAHDHDC_01180 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NAAHDHDC_01181 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
NAAHDHDC_01182 0.0 uup S abc transporter atp-binding protein
NAAHDHDC_01183 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NAAHDHDC_01184 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
NAAHDHDC_01185 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NAAHDHDC_01186 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NAAHDHDC_01187 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NAAHDHDC_01188 7.9e-39 ptsH G phosphocarrier protein Hpr
NAAHDHDC_01189 3.3e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
NAAHDHDC_01190 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
NAAHDHDC_01191 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NAAHDHDC_01192 2.2e-34 nrdH O Glutaredoxin
NAAHDHDC_01193 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NAAHDHDC_01194 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NAAHDHDC_01196 4.2e-71 L Transposase (IS116 IS110 IS902 family)
NAAHDHDC_01197 3.3e-26 L Transposase (IS116 IS110 IS902 family)
NAAHDHDC_01198 1.2e-164 ypuA S secreted protein
NAAHDHDC_01199 1.1e-55 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
NAAHDHDC_01200 5.1e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NAAHDHDC_01201 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NAAHDHDC_01202 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NAAHDHDC_01203 3.4e-258 noxE P NADH oxidase
NAAHDHDC_01204 1.9e-294 yfmM S abc transporter atp-binding protein
NAAHDHDC_01205 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
NAAHDHDC_01206 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NAAHDHDC_01207 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NAAHDHDC_01208 2e-86 S ECF-type riboflavin transporter, S component
NAAHDHDC_01210 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NAAHDHDC_01211 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NAAHDHDC_01214 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NAAHDHDC_01215 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NAAHDHDC_01216 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NAAHDHDC_01217 0.0 smc D Required for chromosome condensation and partitioning
NAAHDHDC_01218 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NAAHDHDC_01219 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NAAHDHDC_01220 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NAAHDHDC_01221 2.4e-92 pat 2.3.1.183 M acetyltransferase
NAAHDHDC_01222 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NAAHDHDC_01223 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NAAHDHDC_01224 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NAAHDHDC_01225 1.2e-62 bioY S biotin transmembrane transporter activity
NAAHDHDC_01226 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
NAAHDHDC_01227 1.5e-138 proV E abc transporter atp-binding protein
NAAHDHDC_01228 4.4e-169 proX M ABC transporter, substrate-binding protein, QAT family
NAAHDHDC_01229 3e-111 proWZ P ABC transporter (Permease
NAAHDHDC_01230 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
NAAHDHDC_01231 1.6e-205 S Protein of unknown function (DUF917)
NAAHDHDC_01232 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NAAHDHDC_01233 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
NAAHDHDC_01234 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NAAHDHDC_01235 1.5e-192 desK 2.7.13.3 T Histidine kinase
NAAHDHDC_01236 1.4e-133 yvfS V ABC-2 type transporter
NAAHDHDC_01237 8.7e-159 XK27_09825 V abc transporter atp-binding protein
NAAHDHDC_01240 8.1e-163 yocS S Transporter
NAAHDHDC_01241 1.2e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
NAAHDHDC_01242 7.5e-115 yvfS V Transporter
NAAHDHDC_01243 3.9e-151 XK27_09825 V abc transporter atp-binding protein
NAAHDHDC_01244 2.7e-14 liaI KT membrane
NAAHDHDC_01245 2.6e-30 liaI KT membrane
NAAHDHDC_01246 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
NAAHDHDC_01247 0.0 V ABC transporter (permease)
NAAHDHDC_01248 1.9e-133 macB2 V ABC transporter, ATP-binding protein
NAAHDHDC_01249 3.1e-165 T Histidine kinase
NAAHDHDC_01250 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NAAHDHDC_01251 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NAAHDHDC_01252 3.3e-69 pbuX F xanthine permease
NAAHDHDC_01253 9.2e-119 pbuX F xanthine permease
NAAHDHDC_01254 1.5e-247 norM V Multidrug efflux pump
NAAHDHDC_01255 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NAAHDHDC_01256 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
NAAHDHDC_01257 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
NAAHDHDC_01258 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
NAAHDHDC_01259 4.8e-25 csbD K CsbD-like
NAAHDHDC_01260 6.2e-228 yfnA E amino acid
NAAHDHDC_01261 5.1e-110 XK27_02070 S nitroreductase
NAAHDHDC_01262 9.5e-150 1.13.11.2 S glyoxalase
NAAHDHDC_01263 5.6e-77 ywnA K Transcriptional regulator
NAAHDHDC_01264 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
NAAHDHDC_01265 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NAAHDHDC_01266 1.4e-110 drgA C Nitroreductase
NAAHDHDC_01267 3e-102 yoaK S Protein of unknown function (DUF1275)
NAAHDHDC_01269 6.8e-161 yvgN C reductase
NAAHDHDC_01270 1.7e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NAAHDHDC_01271 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
NAAHDHDC_01273 1.1e-37 BP1961 P nitric oxide dioxygenase activity
NAAHDHDC_01274 1.4e-54 K response regulator
NAAHDHDC_01275 9.3e-72 S Signal peptide protein, YSIRK family
NAAHDHDC_01277 4.5e-61
NAAHDHDC_01278 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAAHDHDC_01279 1e-137
NAAHDHDC_01280 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
NAAHDHDC_01281 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
NAAHDHDC_01282 5.8e-109 MA20_06410 E LysE type translocator
NAAHDHDC_01283 5.6e-08
NAAHDHDC_01284 2.7e-09
NAAHDHDC_01285 0.0 M family 8
NAAHDHDC_01286 1.5e-162 hrtB V MacB-like periplasmic core domain
NAAHDHDC_01287 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
NAAHDHDC_01288 1.1e-151 V MatE
NAAHDHDC_01290 3.9e-110 C Fe-S oxidoreductases
NAAHDHDC_01291 1.2e-176 EGP Major Facilitator Superfamily
NAAHDHDC_01292 5.5e-258 I radical SAM domain protein
NAAHDHDC_01294 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAAHDHDC_01295 1.4e-150 L Integrase core domain protein
NAAHDHDC_01296 1.8e-87 L transposase activity
NAAHDHDC_01298 2.8e-85
NAAHDHDC_01299 0.0 sbcC L ATPase involved in DNA repair
NAAHDHDC_01300 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NAAHDHDC_01301 0.0 lacL 3.2.1.23 G -beta-galactosidase
NAAHDHDC_01302 0.0 lacS G transporter
NAAHDHDC_01303 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NAAHDHDC_01304 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NAAHDHDC_01305 4e-289 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NAAHDHDC_01306 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NAAHDHDC_01307 2.3e-184 galR K Transcriptional regulator
NAAHDHDC_01308 2.7e-08 L Integrase core domain protein
NAAHDHDC_01309 1.2e-25 L transposition
NAAHDHDC_01310 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NAAHDHDC_01311 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NAAHDHDC_01312 2.5e-101 V abc transporter atp-binding protein
NAAHDHDC_01313 4.3e-40 V abc transporter atp-binding protein
NAAHDHDC_01314 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NAAHDHDC_01315 6.4e-62 L Transposase
NAAHDHDC_01316 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01317 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01318 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01319 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NAAHDHDC_01320 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NAAHDHDC_01321 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NAAHDHDC_01322 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NAAHDHDC_01325 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NAAHDHDC_01326 5.8e-175 vraS 2.7.13.3 T Histidine kinase
NAAHDHDC_01327 3.7e-120 yvqF KT membrane
NAAHDHDC_01328 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NAAHDHDC_01329 2e-132 stp 3.1.3.16 T phosphatase
NAAHDHDC_01330 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NAAHDHDC_01331 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NAAHDHDC_01332 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NAAHDHDC_01333 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NAAHDHDC_01334 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NAAHDHDC_01335 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NAAHDHDC_01336 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
NAAHDHDC_01337 2.1e-148 supH S overlaps another CDS with the same product name
NAAHDHDC_01338 8.6e-63 yvoA_1 K Transcriptional
NAAHDHDC_01339 2.8e-120 skfE V abc transporter atp-binding protein
NAAHDHDC_01340 3.3e-133 V ATPase activity
NAAHDHDC_01341 4.3e-172 oppF P Belongs to the ABC transporter superfamily
NAAHDHDC_01342 2.2e-204 oppD P Belongs to the ABC transporter superfamily
NAAHDHDC_01343 4.9e-168 amiD P ABC transporter (Permease
NAAHDHDC_01344 4.2e-278 amiC P ABC transporter (Permease
NAAHDHDC_01345 3.7e-140 amiA E ABC transporter, substrate-binding protein, family 5
NAAHDHDC_01346 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NAAHDHDC_01347 8.1e-45 L Transposase
NAAHDHDC_01348 4.1e-158 L COG2801 Transposase and inactivated derivatives
NAAHDHDC_01349 1.2e-24 oppF P Belongs to the ABC transporter superfamily
NAAHDHDC_01350 3.8e-45 oppF P Belongs to the ABC transporter superfamily
NAAHDHDC_01351 1.4e-40 tatD L Hydrolase, tatd
NAAHDHDC_01352 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
NAAHDHDC_01353 1e-110 L Integrase core domain protein
NAAHDHDC_01354 1.1e-23 L transposase activity
NAAHDHDC_01355 8.9e-18 L transposase activity
NAAHDHDC_01356 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NAAHDHDC_01357 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NAAHDHDC_01358 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NAAHDHDC_01359 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NAAHDHDC_01360 1.5e-103 yjbK S Adenylate cyclase
NAAHDHDC_01361 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NAAHDHDC_01362 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
NAAHDHDC_01363 2e-58 XK27_04120 S Putative amino acid metabolism
NAAHDHDC_01364 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NAAHDHDC_01365 1.6e-131 puuD T peptidase C26
NAAHDHDC_01366 6.2e-120 radC E Belongs to the UPF0758 family
NAAHDHDC_01367 4.9e-272 rgpF M Rhamnan synthesis protein F
NAAHDHDC_01368 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NAAHDHDC_01369 6.4e-140 rgpC GM Transport permease protein
NAAHDHDC_01370 2e-169 rgpB GT2 M Glycosyltransferase, group 2 family protein
NAAHDHDC_01371 1.1e-222 rgpA GT4 M Domain of unknown function (DUF1972)
NAAHDHDC_01372 5e-174 S Glucosyl transferase GtrII
NAAHDHDC_01373 1.8e-28 S Glucosyl transferase GtrII
NAAHDHDC_01374 1.6e-219 GT4 M transferase activity, transferring glycosyl groups
NAAHDHDC_01375 2e-217 M Psort location CytoplasmicMembrane, score
NAAHDHDC_01376 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
NAAHDHDC_01377 5.9e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
NAAHDHDC_01378 4.6e-42 S Uncharacterized conserved protein (DUF2304)
NAAHDHDC_01379 4.5e-129 arnC M group 2 family protein
NAAHDHDC_01380 1.1e-181 cpsIaJ S Glycosyltransferase like family 2
NAAHDHDC_01381 1e-184 S Glycosyltransferase like family 2
NAAHDHDC_01382 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
NAAHDHDC_01383 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NAAHDHDC_01384 2.9e-235 S Predicted membrane protein (DUF2142)
NAAHDHDC_01385 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NAAHDHDC_01386 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NAAHDHDC_01387 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NAAHDHDC_01388 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NAAHDHDC_01389 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NAAHDHDC_01390 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
NAAHDHDC_01391 2.1e-202 arcT 2.6.1.1 E Aminotransferase
NAAHDHDC_01392 9.4e-136 ET ABC transporter
NAAHDHDC_01393 1.1e-142 ET Belongs to the bacterial solute-binding protein 3 family
NAAHDHDC_01394 2.9e-84 mutT 3.6.1.55 F Nudix family
NAAHDHDC_01395 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NAAHDHDC_01397 1.2e-55 V CAAX protease self-immunity
NAAHDHDC_01398 2.6e-32 S CAAX amino terminal protease family protein
NAAHDHDC_01399 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NAAHDHDC_01400 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAAHDHDC_01401 2.4e-16 XK27_00735
NAAHDHDC_01402 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NAAHDHDC_01404 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NAAHDHDC_01407 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
NAAHDHDC_01408 6.6e-30 ycaO O OsmC-like protein
NAAHDHDC_01410 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
NAAHDHDC_01412 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
NAAHDHDC_01413 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAAHDHDC_01414 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NAAHDHDC_01415 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NAAHDHDC_01416 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
NAAHDHDC_01417 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NAAHDHDC_01418 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NAAHDHDC_01419 2.6e-109 3.1.3.18 S IA, variant 1
NAAHDHDC_01420 2.2e-117 lrgB M effector of murein hydrolase
NAAHDHDC_01421 2.2e-58 lrgA S Effector of murein hydrolase LrgA
NAAHDHDC_01423 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
NAAHDHDC_01424 1.5e-52 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NAAHDHDC_01425 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NAAHDHDC_01426 3.9e-104 wecD M Acetyltransferase GNAT family
NAAHDHDC_01427 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NAAHDHDC_01428 5.1e-96 GK ROK family
NAAHDHDC_01429 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
NAAHDHDC_01430 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
NAAHDHDC_01431 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
NAAHDHDC_01432 2.3e-206 potD P spermidine putrescine ABC transporter
NAAHDHDC_01433 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
NAAHDHDC_01434 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
NAAHDHDC_01435 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NAAHDHDC_01436 7.8e-171 murB 1.3.1.98 M cell wall formation
NAAHDHDC_01437 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NAAHDHDC_01438 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NAAHDHDC_01439 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NAAHDHDC_01440 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NAAHDHDC_01441 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
NAAHDHDC_01442 0.0 ydaO E amino acid
NAAHDHDC_01443 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NAAHDHDC_01444 4.1e-37 ylqC L Belongs to the UPF0109 family
NAAHDHDC_01445 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NAAHDHDC_01446 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NAAHDHDC_01447 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
NAAHDHDC_01448 2.1e-74 S QueT transporter
NAAHDHDC_01449 1.9e-55 L Transposase
NAAHDHDC_01450 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NAAHDHDC_01451 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NAAHDHDC_01452 3.7e-85 ccl S cog cog4708
NAAHDHDC_01453 7.4e-164 rbn E Belongs to the UPF0761 family
NAAHDHDC_01454 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NAAHDHDC_01455 3.3e-231 ytoI K transcriptional regulator containing CBS domains
NAAHDHDC_01456 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NAAHDHDC_01457 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NAAHDHDC_01458 0.0 comEC S Competence protein ComEC
NAAHDHDC_01459 2.2e-96 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NAAHDHDC_01460 1.3e-142 plsC 2.3.1.51 I Acyltransferase
NAAHDHDC_01461 1.7e-77 nodB3 G polysaccharide deacetylase
NAAHDHDC_01462 4.1e-22 nodB3 G polysaccharide deacetylase
NAAHDHDC_01463 2.3e-139 yabB 2.1.1.223 L Methyltransferase
NAAHDHDC_01464 1e-41 yazA L endonuclease containing a URI domain
NAAHDHDC_01465 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NAAHDHDC_01466 2.3e-154 corA P CorA-like protein
NAAHDHDC_01467 1.9e-62 yjqA S Bacterial PH domain
NAAHDHDC_01468 7.8e-100 thiT S Thiamine transporter
NAAHDHDC_01469 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NAAHDHDC_01470 1.9e-201 yjbB G Permeases of the major facilitator superfamily
NAAHDHDC_01471 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NAAHDHDC_01472 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
NAAHDHDC_01473 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NAAHDHDC_01477 1.1e-155 cjaA ET ABC transporter substrate-binding protein
NAAHDHDC_01478 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
NAAHDHDC_01479 3e-106 P ABC transporter (Permease
NAAHDHDC_01480 6e-115 papP P ABC transporter (Permease
NAAHDHDC_01481 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NAAHDHDC_01482 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
NAAHDHDC_01483 0.0 copA 3.6.3.54 P P-type ATPase
NAAHDHDC_01484 2.7e-73 copY K Copper transport repressor, CopY TcrY family
NAAHDHDC_01485 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NAAHDHDC_01486 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NAAHDHDC_01487 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NAAHDHDC_01488 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NAAHDHDC_01489 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NAAHDHDC_01490 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NAAHDHDC_01491 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NAAHDHDC_01492 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
NAAHDHDC_01493 3.2e-56
NAAHDHDC_01494 0.0 ctpE P E1-E2 ATPase
NAAHDHDC_01495 2e-25
NAAHDHDC_01496 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NAAHDHDC_01497 9.7e-28 L transposase activity
NAAHDHDC_01498 2.7e-129 K transcriptional regulator, MerR family
NAAHDHDC_01499 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
NAAHDHDC_01500 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
NAAHDHDC_01501 7.4e-64 XK27_02560 S cog cog2151
NAAHDHDC_01502 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NAAHDHDC_01503 7.7e-227 ytfP S Flavoprotein
NAAHDHDC_01505 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NAAHDHDC_01506 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
NAAHDHDC_01507 2.7e-183 ecsB U ABC transporter
NAAHDHDC_01508 2.3e-133 ecsA V abc transporter atp-binding protein
NAAHDHDC_01509 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NAAHDHDC_01510 5.6e-12
NAAHDHDC_01511 2.6e-55 S CD20-like family
NAAHDHDC_01512 2.1e-106
NAAHDHDC_01514 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NAAHDHDC_01515 6.9e-206 ylbM S Belongs to the UPF0348 family
NAAHDHDC_01516 2e-140 yqeM Q Methyltransferase domain protein
NAAHDHDC_01517 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NAAHDHDC_01518 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NAAHDHDC_01519 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NAAHDHDC_01520 3.5e-49 yhbY J RNA-binding protein
NAAHDHDC_01521 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NAAHDHDC_01522 1.8e-98 yqeG S hydrolase of the HAD superfamily
NAAHDHDC_01523 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NAAHDHDC_01524 1.3e-57
NAAHDHDC_01525 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NAAHDHDC_01526 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NAAHDHDC_01527 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NAAHDHDC_01528 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
NAAHDHDC_01529 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NAAHDHDC_01530 5.1e-77 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NAAHDHDC_01531 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NAAHDHDC_01532 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
NAAHDHDC_01533 6.8e-101 pncA Q isochorismatase
NAAHDHDC_01534 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NAAHDHDC_01535 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NAAHDHDC_01536 2.4e-75 XK27_03180 T universal stress protein
NAAHDHDC_01539 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NAAHDHDC_01540 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NAAHDHDC_01541 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NAAHDHDC_01542 0.0 yjcE P NhaP-type Na H and K H antiporters
NAAHDHDC_01544 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
NAAHDHDC_01545 1.3e-184 yhcC S radical SAM protein
NAAHDHDC_01546 2.2e-196 ylbL T Belongs to the peptidase S16 family
NAAHDHDC_01547 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NAAHDHDC_01548 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
NAAHDHDC_01549 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NAAHDHDC_01550 1.5e-09 S Protein of unknown function (DUF4059)
NAAHDHDC_01551 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
NAAHDHDC_01552 4.7e-163 yxeN P ABC transporter (Permease
NAAHDHDC_01553 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NAAHDHDC_01555 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NAAHDHDC_01556 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NAAHDHDC_01557 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
NAAHDHDC_01558 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NAAHDHDC_01559 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
NAAHDHDC_01560 2.9e-87 D nuclear chromosome segregation
NAAHDHDC_01561 1.5e-127 ybbM S transport system, permease component
NAAHDHDC_01562 1.2e-117 ybbL S abc transporter atp-binding protein
NAAHDHDC_01563 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NAAHDHDC_01564 4.6e-140 cppA E CppA N-terminal
NAAHDHDC_01565 5e-44 V CAAX protease self-immunity
NAAHDHDC_01566 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NAAHDHDC_01567 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NAAHDHDC_01570 3e-47 spiA K sequence-specific DNA binding
NAAHDHDC_01571 2.9e-28 blpT
NAAHDHDC_01572 6.7e-98 blpT
NAAHDHDC_01577 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
NAAHDHDC_01580 8.9e-133 agrA KT phosphorelay signal transduction system
NAAHDHDC_01581 3e-235 blpH 2.7.13.3 T protein histidine kinase activity
NAAHDHDC_01583 7.3e-237 mesE M Transport protein ComB
NAAHDHDC_01584 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NAAHDHDC_01585 0.0 mdlB V abc transporter atp-binding protein
NAAHDHDC_01586 0.0 mdlA V abc transporter atp-binding protein
NAAHDHDC_01588 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
NAAHDHDC_01589 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NAAHDHDC_01590 2.3e-72 yutD J protein conserved in bacteria
NAAHDHDC_01591 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NAAHDHDC_01593 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NAAHDHDC_01594 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NAAHDHDC_01595 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NAAHDHDC_01596 8.1e-46 ftsL D cell division protein FtsL
NAAHDHDC_01597 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NAAHDHDC_01598 3e-128
NAAHDHDC_01599 9.7e-32 yhaI J Protein of unknown function (DUF805)
NAAHDHDC_01600 1.3e-08 D nuclear chromosome segregation
NAAHDHDC_01601 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NAAHDHDC_01602 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NAAHDHDC_01603 2.2e-285 XK27_00765
NAAHDHDC_01604 8.1e-134 ecsA_2 V abc transporter atp-binding protein
NAAHDHDC_01605 5.2e-125 S Protein of unknown function (DUF554)
NAAHDHDC_01606 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NAAHDHDC_01607 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NAAHDHDC_01608 9.8e-57 liaI S membrane
NAAHDHDC_01609 7e-10 XK27_02470 K LytTr DNA-binding domain protein
NAAHDHDC_01610 1.8e-65 KT response to antibiotic
NAAHDHDC_01611 5.2e-81 yebC M Membrane
NAAHDHDC_01612 2.9e-18 yebC M Membrane
NAAHDHDC_01613 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
NAAHDHDC_01614 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NAAHDHDC_01615 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NAAHDHDC_01616 1.9e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NAAHDHDC_01617 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NAAHDHDC_01618 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NAAHDHDC_01619 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NAAHDHDC_01620 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NAAHDHDC_01622 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NAAHDHDC_01623 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NAAHDHDC_01624 0.0 scrA 2.7.1.211 G pts system
NAAHDHDC_01625 4.1e-291 scrB 3.2.1.26 GH32 G invertase
NAAHDHDC_01626 7.5e-180 scrR K Transcriptional
NAAHDHDC_01627 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NAAHDHDC_01628 3.4e-62 yqhY S protein conserved in bacteria
NAAHDHDC_01629 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NAAHDHDC_01630 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
NAAHDHDC_01631 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NAAHDHDC_01633 8e-44 V 'abc transporter, ATP-binding protein
NAAHDHDC_01634 1e-58 V 'abc transporter, ATP-binding protein
NAAHDHDC_01637 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NAAHDHDC_01638 2e-169 corA P COG0598 Mg2 and Co2 transporters
NAAHDHDC_01639 3.1e-124 XK27_01040 S Pfam PF06570
NAAHDHDC_01641 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NAAHDHDC_01642 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NAAHDHDC_01643 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NAAHDHDC_01644 2.8e-31 XK27_05745
NAAHDHDC_01645 2.5e-230 mutY L A G-specific adenine glycosylase
NAAHDHDC_01650 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NAAHDHDC_01651 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NAAHDHDC_01652 1e-93 cvpA S toxin biosynthetic process
NAAHDHDC_01653 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NAAHDHDC_01654 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NAAHDHDC_01655 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NAAHDHDC_01656 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NAAHDHDC_01657 2e-47 azlD E branched-chain amino acid
NAAHDHDC_01658 1.8e-114 azlC E AzlC protein
NAAHDHDC_01659 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NAAHDHDC_01660 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NAAHDHDC_01661 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NAAHDHDC_01662 2.5e-33 ykzG S Belongs to the UPF0356 family
NAAHDHDC_01663 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NAAHDHDC_01664 2.7e-40 pscB M CHAP domain protein
NAAHDHDC_01665 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
NAAHDHDC_01666 8.5e-63 glnR K Transcriptional regulator
NAAHDHDC_01667 1.3e-87 S Fusaric acid resistance protein-like
NAAHDHDC_01668 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NAAHDHDC_01669 3.2e-42 L Transposase
NAAHDHDC_01670 1.9e-46 L transposase activity
NAAHDHDC_01671 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NAAHDHDC_01672 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NAAHDHDC_01673 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NAAHDHDC_01674 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NAAHDHDC_01675 1.1e-142 purR 2.4.2.7 F operon repressor
NAAHDHDC_01676 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
NAAHDHDC_01677 6.9e-173 rmuC S RmuC domain protein
NAAHDHDC_01678 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
NAAHDHDC_01679 8.6e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NAAHDHDC_01680 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NAAHDHDC_01682 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NAAHDHDC_01683 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NAAHDHDC_01684 1.6e-143 tatD L Hydrolase, tatd
NAAHDHDC_01685 7.2e-74 yccU S CoA-binding protein
NAAHDHDC_01686 4.8e-51 trxA O Belongs to the thioredoxin family
NAAHDHDC_01687 1.9e-141 S Macro domain protein
NAAHDHDC_01688 2e-09 L thioesterase
NAAHDHDC_01689 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
NAAHDHDC_01692 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NAAHDHDC_01693 5e-84 L Transposase
NAAHDHDC_01694 1e-13 rpmH J Ribosomal protein L34
NAAHDHDC_01695 2e-186 jag S RNA-binding protein
NAAHDHDC_01696 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NAAHDHDC_01697 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NAAHDHDC_01698 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
NAAHDHDC_01699 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NAAHDHDC_01700 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NAAHDHDC_01701 6.7e-81 amiA E transmembrane transport
NAAHDHDC_01702 4.2e-74 amiA E transmembrane transport
NAAHDHDC_01703 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NAAHDHDC_01704 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NAAHDHDC_01705 3.5e-50 S Protein of unknown function (DUF3397)
NAAHDHDC_01706 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NAAHDHDC_01707 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
NAAHDHDC_01708 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
NAAHDHDC_01709 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NAAHDHDC_01710 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NAAHDHDC_01711 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
NAAHDHDC_01712 4.3e-77 XK27_09620 S reductase
NAAHDHDC_01713 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
NAAHDHDC_01714 1.2e-131 XK27_09615 S PAS domain
NAAHDHDC_01715 1.9e-07 fnt P Formate nitrite transporter
NAAHDHDC_01716 6.4e-54 fnt P Formate nitrite transporter
NAAHDHDC_01717 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
NAAHDHDC_01718 2.8e-185 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NAAHDHDC_01719 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NAAHDHDC_01720 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NAAHDHDC_01721 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NAAHDHDC_01722 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NAAHDHDC_01723 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NAAHDHDC_01724 1.6e-21 S glycolate biosynthetic process
NAAHDHDC_01725 1.5e-64 S phosphatase activity
NAAHDHDC_01726 2e-157 rrmA 2.1.1.187 Q methyltransferase
NAAHDHDC_01729 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NAAHDHDC_01730 1.9e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NAAHDHDC_01731 2.4e-36 yeeD O sulfur carrier activity
NAAHDHDC_01732 1.8e-187 yeeE S Sulphur transport
NAAHDHDC_01733 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NAAHDHDC_01734 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NAAHDHDC_01735 4.1e-09 S Domain of unknown function (DUF4651)
NAAHDHDC_01736 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NAAHDHDC_01737 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NAAHDHDC_01738 1.8e-111 S CAAX amino terminal protease family protein
NAAHDHDC_01740 5e-67 V CAAX protease self-immunity
NAAHDHDC_01741 1.4e-33 V CAAX protease self-immunity
NAAHDHDC_01742 8.8e-27 lanR K sequence-specific DNA binding
NAAHDHDC_01743 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NAAHDHDC_01744 7.7e-177 ytxK 2.1.1.72 L DNA methylase
NAAHDHDC_01745 6.8e-13 comGF U Putative Competence protein ComGF
NAAHDHDC_01746 4e-72 comGF U Competence protein ComGF
NAAHDHDC_01747 1.4e-15 NU Type II secretory pathway pseudopilin
NAAHDHDC_01748 1.8e-57 cglD NU Competence protein
NAAHDHDC_01749 8.5e-43 comGC U Required for transformation and DNA binding
NAAHDHDC_01750 9.2e-153 cglB NU type II secretion system
NAAHDHDC_01751 1.9e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NAAHDHDC_01752 2.9e-68 S cog cog4699
NAAHDHDC_01753 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAAHDHDC_01754 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAAHDHDC_01755 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NAAHDHDC_01756 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NAAHDHDC_01757 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NAAHDHDC_01758 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
NAAHDHDC_01759 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NAAHDHDC_01760 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NAAHDHDC_01761 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NAAHDHDC_01762 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
NAAHDHDC_01763 1.8e-57 asp S cog cog1302
NAAHDHDC_01764 3.2e-226 norN V Mate efflux family protein
NAAHDHDC_01765 1.9e-278 thrC 4.2.3.1 E Threonine synthase
NAAHDHDC_01766 1.9e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NAAHDHDC_01767 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
NAAHDHDC_01768 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NAAHDHDC_01769 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NAAHDHDC_01770 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
NAAHDHDC_01771 0.0 pepO 3.4.24.71 O Peptidase family M13
NAAHDHDC_01772 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NAAHDHDC_01773 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NAAHDHDC_01774 1.3e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NAAHDHDC_01775 1.4e-54 treB 2.7.1.201 G PTS System
NAAHDHDC_01776 5.8e-21 treR K DNA-binding transcription factor activity
NAAHDHDC_01777 1.2e-85 treR K trehalose operon
NAAHDHDC_01778 3.3e-95 ywlG S Belongs to the UPF0340 family
NAAHDHDC_01781 2e-35 L PFAM Integrase, catalytic core
NAAHDHDC_01782 2e-94 L PFAM Integrase, catalytic core
NAAHDHDC_01783 3.3e-46 K Putative DNA-binding domain
NAAHDHDC_01784 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
NAAHDHDC_01785 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NAAHDHDC_01786 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
NAAHDHDC_01791 1e-39
NAAHDHDC_01792 6.5e-31
NAAHDHDC_01793 5e-31 S Hypothetical protein (DUF2513)
NAAHDHDC_01794 7.7e-13
NAAHDHDC_01796 3.7e-216 S MvaI/BcnI restriction endonuclease family
NAAHDHDC_01798 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
NAAHDHDC_01799 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
NAAHDHDC_01801 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
NAAHDHDC_01802 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
NAAHDHDC_01803 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
NAAHDHDC_01804 3.3e-09 L PFAM Integrase, catalytic core
NAAHDHDC_01805 1.8e-111 L PFAM Integrase, catalytic core
NAAHDHDC_01806 3.3e-62 rplQ J ribosomal protein l17
NAAHDHDC_01807 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NAAHDHDC_01808 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NAAHDHDC_01809 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NAAHDHDC_01810 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NAAHDHDC_01811 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NAAHDHDC_01812 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NAAHDHDC_01813 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NAAHDHDC_01814 4.4e-58 rplO J binds to the 23S rRNA
NAAHDHDC_01815 2.5e-23 rpmD J ribosomal protein l30
NAAHDHDC_01816 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NAAHDHDC_01817 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NAAHDHDC_01818 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NAAHDHDC_01819 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NAAHDHDC_01820 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NAAHDHDC_01821 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NAAHDHDC_01822 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NAAHDHDC_01823 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NAAHDHDC_01824 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NAAHDHDC_01825 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NAAHDHDC_01826 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NAAHDHDC_01827 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NAAHDHDC_01828 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NAAHDHDC_01829 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NAAHDHDC_01830 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NAAHDHDC_01831 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NAAHDHDC_01832 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
NAAHDHDC_01833 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NAAHDHDC_01834 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NAAHDHDC_01835 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NAAHDHDC_01836 0.0 XK27_09800 I Acyltransferase
NAAHDHDC_01837 1.7e-35 XK27_09805 S MORN repeat protein
NAAHDHDC_01838 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NAAHDHDC_01839 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NAAHDHDC_01840 1.5e-89 adk 2.7.4.3 F topology modulation protein
NAAHDHDC_01841 8.6e-127 Z012_04635 K sequence-specific DNA binding
NAAHDHDC_01843 6.3e-16 C Radical SAM
NAAHDHDC_01844 3.4e-191 C Radical SAM
NAAHDHDC_01845 3.9e-287 V ABC transporter transmembrane region
NAAHDHDC_01846 2.5e-89 K sequence-specific DNA binding
NAAHDHDC_01847 1e-36 L Replication initiation factor
NAAHDHDC_01848 1.4e-107 L Replication initiation factor
NAAHDHDC_01849 1.9e-18 S Domain of unknown function (DUF3173)
NAAHDHDC_01850 3.5e-216 int L Belongs to the 'phage' integrase family
NAAHDHDC_01852 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NAAHDHDC_01853 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NAAHDHDC_01854 2.8e-44 yrzL S Belongs to the UPF0297 family
NAAHDHDC_01855 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NAAHDHDC_01856 4.2e-44 yrzB S Belongs to the UPF0473 family
NAAHDHDC_01857 6.6e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
NAAHDHDC_01858 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NAAHDHDC_01859 7.5e-14
NAAHDHDC_01860 2.6e-91 XK27_10930 K acetyltransferase
NAAHDHDC_01861 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NAAHDHDC_01862 2.3e-41 yaaA S Belongs to the UPF0246 family
NAAHDHDC_01863 1.2e-50 yaaA S Belongs to the UPF0246 family
NAAHDHDC_01864 9.9e-169 XK27_01785 S cog cog1284
NAAHDHDC_01865 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NAAHDHDC_01867 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
NAAHDHDC_01868 5.7e-52 metE 2.1.1.14 E Methionine synthase
NAAHDHDC_01869 7.6e-64 metE 2.1.1.14 E Methionine synthase
NAAHDHDC_01870 9.2e-36 metE 2.1.1.14 E Methionine synthase
NAAHDHDC_01871 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NAAHDHDC_01872 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NAAHDHDC_01874 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
NAAHDHDC_01875 2.7e-95 S Hydrophobic domain protein
NAAHDHDC_01877 3.7e-27 S Membrane
NAAHDHDC_01878 3.1e-101
NAAHDHDC_01879 1.8e-23 S Small integral membrane protein
NAAHDHDC_01880 1.1e-71 M Protein conserved in bacteria
NAAHDHDC_01881 4.9e-12 K CsbD-like
NAAHDHDC_01882 3.5e-97 nudL L hydrolase
NAAHDHDC_01883 3.4e-13 nudL L hydrolase
NAAHDHDC_01884 4e-19 K negative regulation of transcription, DNA-templated
NAAHDHDC_01885 1.7e-23 K negative regulation of transcription, DNA-templated
NAAHDHDC_01887 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
NAAHDHDC_01888 1.8e-88 S Putative adhesin
NAAHDHDC_01889 3.9e-161 XK27_06930 V domain protein
NAAHDHDC_01890 6.4e-96 XK27_06935 K transcriptional regulator
NAAHDHDC_01891 4.8e-55 ypaA M Membrane
NAAHDHDC_01892 2.7e-08
NAAHDHDC_01893 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NAAHDHDC_01894 8.2e-48 veg S Biofilm formation stimulator VEG
NAAHDHDC_01895 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NAAHDHDC_01896 3.9e-70 rplI J binds to the 23S rRNA
NAAHDHDC_01897 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NAAHDHDC_01898 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NAAHDHDC_01899 1.5e-77 F NUDIX domain
NAAHDHDC_01900 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NAAHDHDC_01901 0.0 S Bacterial membrane protein, YfhO
NAAHDHDC_01902 1.5e-88 isaA GH23 M Immunodominant staphylococcal antigen A
NAAHDHDC_01903 5.3e-85 lytE M LysM domain protein
NAAHDHDC_01904 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAAHDHDC_01905 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAAHDHDC_01906 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NAAHDHDC_01907 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NAAHDHDC_01908 6.3e-138 ymfM S sequence-specific DNA binding
NAAHDHDC_01909 3.1e-242 ymfH S Peptidase M16
NAAHDHDC_01910 4.8e-235 ymfF S Peptidase M16
NAAHDHDC_01911 1.6e-45 yaaA S S4 domain protein YaaA
NAAHDHDC_01912 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NAAHDHDC_01913 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NAAHDHDC_01914 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NAAHDHDC_01915 4.2e-153 yvjA S membrane
NAAHDHDC_01916 6.7e-306 ybiT S abc transporter atp-binding protein
NAAHDHDC_01917 0.0 XK27_10405 S Bacterial membrane protein YfhO
NAAHDHDC_01921 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
NAAHDHDC_01922 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NAAHDHDC_01923 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NAAHDHDC_01924 8.5e-134 parB K Belongs to the ParB family
NAAHDHDC_01925 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NAAHDHDC_01926 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NAAHDHDC_01927 1.1e-29 yyzM S Protein conserved in bacteria
NAAHDHDC_01928 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NAAHDHDC_01929 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NAAHDHDC_01930 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NAAHDHDC_01931 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NAAHDHDC_01932 2.7e-61 divIC D Septum formation initiator
NAAHDHDC_01934 8.7e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NAAHDHDC_01935 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NAAHDHDC_01936 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NAAHDHDC_01937 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NAAHDHDC_01938 1.3e-137 L Transposase
NAAHDHDC_01948 1.2e-165 L integrase core domain
NAAHDHDC_01949 2e-52 L Transposase
NAAHDHDC_01950 1.6e-249 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)