ORF_ID e_value Gene_name EC_number CAZy COGs Description
MABCCOOD_00008 5.3e-11
MABCCOOD_00014 1.3e-140 mreC M Involved in formation and maintenance of cell shape
MABCCOOD_00015 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MABCCOOD_00016 5.5e-94 usp 3.5.1.28 CBM50 S CHAP domain
MABCCOOD_00017 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MABCCOOD_00018 5.9e-219 araT 2.6.1.1 E Aminotransferase
MABCCOOD_00019 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
MABCCOOD_00020 3.9e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MABCCOOD_00021 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MABCCOOD_00022 1.2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MABCCOOD_00023 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MABCCOOD_00024 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MABCCOOD_00025 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MABCCOOD_00026 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MABCCOOD_00027 7.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MABCCOOD_00028 1e-90 L transposase activity
MABCCOOD_00029 3.5e-50 L transposition
MABCCOOD_00030 2e-32 L Integrase core domain protein
MABCCOOD_00031 2.3e-161 S CHAP domain
MABCCOOD_00032 2e-241 purD 6.3.4.13 F Belongs to the GARS family
MABCCOOD_00033 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MABCCOOD_00034 8.5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MABCCOOD_00035 4.3e-138 1.1.1.169 H Ketopantoate reductase
MABCCOOD_00036 2.8e-23
MABCCOOD_00037 2.3e-136 J Domain of unknown function (DUF4041)
MABCCOOD_00038 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MABCCOOD_00039 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MABCCOOD_00040 2.9e-210 sip L Belongs to the 'phage' integrase family
MABCCOOD_00041 2.2e-14 K Cro/C1-type HTH DNA-binding domain
MABCCOOD_00042 8e-20 K TRANSCRIPTIONal
MABCCOOD_00046 9e-22
MABCCOOD_00047 2.4e-145 KL Phage plasmid primase P4 family
MABCCOOD_00048 1.5e-280 S DNA primase
MABCCOOD_00050 3.5e-13
MABCCOOD_00052 2.2e-18 L RePlication protein
MABCCOOD_00054 2e-171 aaxC E Arginine ornithine antiporter
MABCCOOD_00055 9.1e-122 4.1.1.22 H Histidine carboxylase PI chain
MABCCOOD_00057 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
MABCCOOD_00058 8.9e-206 potD P spermidine putrescine ABC transporter
MABCCOOD_00059 3.1e-268 clcA P Chloride transporter, ClC family
MABCCOOD_00060 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
MABCCOOD_00061 1.9e-21 L Helix-turn-helix domain
MABCCOOD_00062 1.1e-82 L Helix-turn-helix domain
MABCCOOD_00063 9.8e-163 L Integrase core domain protein
MABCCOOD_00064 1.3e-29 rpsT J rRNA binding
MABCCOOD_00065 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
MABCCOOD_00066 9.8e-106 rsmC 2.1.1.172 J Methyltransferase small domain protein
MABCCOOD_00067 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MABCCOOD_00068 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MABCCOOD_00069 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MABCCOOD_00070 1.4e-38 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MABCCOOD_00071 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MABCCOOD_00072 1.6e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MABCCOOD_00073 6.4e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MABCCOOD_00074 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
MABCCOOD_00075 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MABCCOOD_00076 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MABCCOOD_00077 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MABCCOOD_00078 3.1e-81 ypmB S Protein conserved in bacteria
MABCCOOD_00079 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MABCCOOD_00080 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MABCCOOD_00081 1.5e-07
MABCCOOD_00082 2.4e-30
MABCCOOD_00083 3e-13
MABCCOOD_00084 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
MABCCOOD_00085 9.8e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MABCCOOD_00086 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MABCCOOD_00087 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MABCCOOD_00088 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
MABCCOOD_00089 4.2e-18 D nuclear chromosome segregation
MABCCOOD_00090 5.3e-136 yejC S cyclic nucleotide-binding protein
MABCCOOD_00091 1.2e-163 rapZ S Displays ATPase and GTPase activities
MABCCOOD_00092 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MABCCOOD_00093 8.7e-162 whiA K May be required for sporulation
MABCCOOD_00094 8.2e-120 pepD E Dipeptidase
MABCCOOD_00095 5.8e-41 pepD E dipeptidase activity
MABCCOOD_00096 5.4e-32 cspD K Cold shock protein domain
MABCCOOD_00097 3.6e-42 K Cold-Shock Protein
MABCCOOD_00098 0.0 copB 3.6.3.4 P haloacid dehalogenase-like hydrolase
MABCCOOD_00099 3.8e-28 L Transposase
MABCCOOD_00100 2.9e-190 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MABCCOOD_00101 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MABCCOOD_00102 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MABCCOOD_00103 1.5e-59 cysE 2.3.1.30 E serine acetyltransferase
MABCCOOD_00104 1.5e-55 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
MABCCOOD_00105 3.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
MABCCOOD_00106 1.2e-155 glcU U Glucose uptake
MABCCOOD_00107 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
MABCCOOD_00108 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
MABCCOOD_00109 1.3e-88 XK27_10720 D peptidase activity
MABCCOOD_00110 8.9e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
MABCCOOD_00111 1.7e-08
MABCCOOD_00113 2.7e-172 yeiH S Membrane
MABCCOOD_00114 2.9e-115 mur1 NU muramidase
MABCCOOD_00115 1.9e-83 L transposition
MABCCOOD_00116 2.6e-166 cpsY K Transcriptional regulator
MABCCOOD_00117 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MABCCOOD_00118 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
MABCCOOD_00119 4e-105 artQ P ABC transporter (Permease
MABCCOOD_00120 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
MABCCOOD_00121 1.2e-157 aatB ET ABC transporter substrate-binding protein
MABCCOOD_00122 3.5e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MABCCOOD_00123 4.2e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MABCCOOD_00124 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
MABCCOOD_00125 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
MABCCOOD_00126 3.6e-49 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
MABCCOOD_00127 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MABCCOOD_00128 2.9e-125 gntR1 K transcriptional
MABCCOOD_00129 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MABCCOOD_00130 3.2e-265 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MABCCOOD_00131 4.1e-87 niaX
MABCCOOD_00132 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
MABCCOOD_00133 1.8e-127 K DNA-binding helix-turn-helix protein
MABCCOOD_00134 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MABCCOOD_00135 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MABCCOOD_00136 8.2e-168 GK ROK family
MABCCOOD_00137 8.3e-159 dprA LU DNA protecting protein DprA
MABCCOOD_00138 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MABCCOOD_00139 6.7e-153 S TraX protein
MABCCOOD_00140 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MABCCOOD_00141 1.8e-251 T PhoQ Sensor
MABCCOOD_00142 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MABCCOOD_00143 1.1e-152 XK27_05470 E Methionine synthase
MABCCOOD_00144 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MABCCOOD_00145 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MABCCOOD_00146 1.8e-51 IQ Acetoin reductase
MABCCOOD_00147 3.9e-19 IQ Acetoin reductase
MABCCOOD_00148 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MABCCOOD_00149 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MABCCOOD_00152 1.3e-212 pqqE C radical SAM domain protein
MABCCOOD_00153 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
MABCCOOD_00154 6.6e-61 EGP Major facilitator Superfamily
MABCCOOD_00155 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MABCCOOD_00156 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MABCCOOD_00157 4.3e-13
MABCCOOD_00158 8e-160 L Transposase
MABCCOOD_00159 6.4e-104 V ABC transporter (Permease
MABCCOOD_00160 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MABCCOOD_00161 1.6e-10
MABCCOOD_00162 1.2e-97 K Transcriptional regulator, TetR family
MABCCOOD_00163 1.8e-159 czcD P cation diffusion facilitator family transporter
MABCCOOD_00164 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MABCCOOD_00165 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
MABCCOOD_00166 6e-08 S Hydrolases of the alpha beta superfamily
MABCCOOD_00167 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
MABCCOOD_00168 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
MABCCOOD_00171 1.2e-143 2.4.2.3 F Phosphorylase superfamily
MABCCOOD_00172 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
MABCCOOD_00173 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
MABCCOOD_00174 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
MABCCOOD_00176 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MABCCOOD_00177 3.7e-190
MABCCOOD_00178 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
MABCCOOD_00179 3.5e-28 3.4.13.21 I Protein conserved in bacteria
MABCCOOD_00181 5.7e-118 S TraX protein
MABCCOOD_00182 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
MABCCOOD_00183 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MABCCOOD_00184 7.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MABCCOOD_00185 1.3e-187 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MABCCOOD_00186 1.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MABCCOOD_00187 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
MABCCOOD_00188 0.0 csm1 S CRISPR-associated protein Csm1 family
MABCCOOD_00189 2.5e-62 csm2 L Csm2 Type III-A
MABCCOOD_00190 1.6e-117 csm3 L RAMP superfamily
MABCCOOD_00191 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
MABCCOOD_00192 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
MABCCOOD_00194 9.5e-32 csm6 S Psort location Cytoplasmic, score
MABCCOOD_00195 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MABCCOOD_00196 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MABCCOOD_00197 1.6e-266 dtpT E transporter
MABCCOOD_00198 1.4e-62 yecS P ABC transporter (Permease
MABCCOOD_00199 2.3e-20 yecS P amino acid transport
MABCCOOD_00201 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MABCCOOD_00202 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MABCCOOD_00203 3.1e-240 agcS E (Alanine) symporter
MABCCOOD_00204 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MABCCOOD_00205 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
MABCCOOD_00206 2.2e-134 S haloacid dehalogenase-like hydrolase
MABCCOOD_00207 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MABCCOOD_00208 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
MABCCOOD_00209 6.3e-32 M1-755 P Hemerythrin HHE cation binding domain protein
MABCCOOD_00210 6.1e-84 XK27_04775 S hemerythrin HHE cation binding domain
MABCCOOD_00211 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
MABCCOOD_00212 3.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MABCCOOD_00213 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MABCCOOD_00214 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MABCCOOD_00215 1.9e-43 yktA S Belongs to the UPF0223 family
MABCCOOD_00216 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MABCCOOD_00217 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MABCCOOD_00218 3.3e-158 pstS P phosphate
MABCCOOD_00219 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
MABCCOOD_00220 1.2e-155 pstA P phosphate transport system permease
MABCCOOD_00221 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MABCCOOD_00222 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MABCCOOD_00223 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
MABCCOOD_00224 0.0 pepN 3.4.11.2 E aminopeptidase
MABCCOOD_00225 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MABCCOOD_00226 8.5e-187 lplA 6.3.1.20 H Lipoate-protein ligase
MABCCOOD_00227 3.4e-17
MABCCOOD_00229 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MABCCOOD_00230 1.4e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
MABCCOOD_00231 2.3e-23 L Transposase
MABCCOOD_00232 4.6e-25 tatA U protein secretion
MABCCOOD_00233 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MABCCOOD_00234 7.4e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
MABCCOOD_00235 3.3e-233 ycdB P peroxidase
MABCCOOD_00236 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
MABCCOOD_00237 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MABCCOOD_00238 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MABCCOOD_00239 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MABCCOOD_00240 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MABCCOOD_00241 1.1e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MABCCOOD_00242 1.9e-186 3.5.1.28 M GBS Bsp-like repeat
MABCCOOD_00243 1.9e-65 3.2.1.17 M lysozyme activity
MABCCOOD_00244 3.8e-11 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MABCCOOD_00245 0.0 lpdA 1.8.1.4 C Dehydrogenase
MABCCOOD_00246 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MABCCOOD_00247 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MABCCOOD_00248 1.7e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MABCCOOD_00249 0.0 S the current gene model (or a revised gene model) may contain a frame shift
MABCCOOD_00250 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MABCCOOD_00251 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MABCCOOD_00252 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MABCCOOD_00253 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
MABCCOOD_00254 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
MABCCOOD_00255 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
MABCCOOD_00256 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
MABCCOOD_00257 1.2e-157 rssA S Phospholipase, patatin family
MABCCOOD_00258 1.8e-69 estA E GDSL-like protein
MABCCOOD_00259 3.4e-29 estA E Lysophospholipase L1 and related esterases
MABCCOOD_00260 5.9e-291 S unusual protein kinase
MABCCOOD_00261 4.9e-39 S granule-associated protein
MABCCOOD_00262 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MABCCOOD_00263 7e-116 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MABCCOOD_00264 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MABCCOOD_00265 2.5e-198 S hmm pf01594
MABCCOOD_00266 5.1e-102 G Belongs to the phosphoglycerate mutase family
MABCCOOD_00267 1.5e-33 G Belongs to the phosphoglycerate mutase family
MABCCOOD_00268 9.2e-93 V VanZ like family
MABCCOOD_00269 3.2e-51 tnp L DDE domain
MABCCOOD_00270 1.8e-24 S Bacterial transferase hexapeptide (six repeats)
MABCCOOD_00271 1.7e-156 L EVIDENCE EXPERIMENTAL PMID 1328163 BIO14.04 Transposon related functions. BELONGS TO THE IS3 IS150 IS904 FAMILY OF TRANSPOSASE. There are 7 such elements in the chromosome
MABCCOOD_00272 3.7e-58 L Helix-turn-helix domain
MABCCOOD_00273 1.2e-15 L Transposase
MABCCOOD_00274 1.3e-51 L Helix-turn-helix domain
MABCCOOD_00275 1e-110 L PFAM Integrase catalytic region
MABCCOOD_00276 5.7e-228 L Transposase
MABCCOOD_00277 1.4e-192 wbbI M transferase activity, transferring glycosyl groups
MABCCOOD_00278 4.1e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
MABCCOOD_00279 1.6e-242 epsU S Polysaccharide biosynthesis protein
MABCCOOD_00280 1.4e-100 cps3F
MABCCOOD_00281 3.4e-135 M Glycosyltransferase like family 2
MABCCOOD_00282 3.4e-119 M Glycosyltransferase, group 2 family protein
MABCCOOD_00284 3.4e-135 M transferase activity, transferring glycosyl groups
MABCCOOD_00285 3.4e-211 wcoF M Glycosyltransferase, group 1 family protein
MABCCOOD_00286 5.3e-220 rgpAc GT4 M group 1 family protein
MABCCOOD_00287 5.2e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MABCCOOD_00288 1e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
MABCCOOD_00289 2.2e-104 cps4C M biosynthesis protein
MABCCOOD_00290 8.6e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
MABCCOOD_00291 1e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
MABCCOOD_00292 5.8e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
MABCCOOD_00293 2.4e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
MABCCOOD_00294 1.2e-65 yfeJ 6.3.5.2 F glutamine amidotransferase
MABCCOOD_00295 2e-63 clcA_2 P chloride
MABCCOOD_00296 5.8e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MABCCOOD_00297 1.3e-41 S Protein of unknown function (DUF1697)
MABCCOOD_00298 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MABCCOOD_00299 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MABCCOOD_00301 4e-21 V Glucan-binding protein C
MABCCOOD_00302 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
MABCCOOD_00303 2.9e-273 pepV 3.5.1.18 E Dipeptidase
MABCCOOD_00304 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MABCCOOD_00305 6.5e-84 XK27_03610 K Gnat family
MABCCOOD_00306 2.2e-84 L Transposase
MABCCOOD_00307 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MABCCOOD_00308 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MABCCOOD_00309 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MABCCOOD_00310 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MABCCOOD_00311 2.8e-18 M LysM domain
MABCCOOD_00312 2.9e-90 ebsA S Family of unknown function (DUF5322)
MABCCOOD_00313 4.2e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MABCCOOD_00314 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MABCCOOD_00315 2.4e-223 G COG0457 FOG TPR repeat
MABCCOOD_00316 8.1e-176 yubA S permease
MABCCOOD_00317 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
MABCCOOD_00318 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MABCCOOD_00319 2.5e-124 ftsE D cell division ATP-binding protein FtsE
MABCCOOD_00320 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MABCCOOD_00321 2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MABCCOOD_00322 1.7e-164 yjjH S Calcineurin-like phosphoesterase
MABCCOOD_00323 3.3e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MABCCOOD_00324 0.0 pacL 3.6.3.8 P cation transport ATPase
MABCCOOD_00325 2.6e-67 ywiB S Domain of unknown function (DUF1934)
MABCCOOD_00326 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
MABCCOOD_00327 9.2e-147 yidA S hydrolases of the HAD superfamily
MABCCOOD_00328 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
MABCCOOD_00329 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
MABCCOOD_00330 1.5e-247 vicK 2.7.13.3 T Histidine kinase
MABCCOOD_00331 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MABCCOOD_00332 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
MABCCOOD_00333 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MABCCOOD_00334 7.7e-118 gltJ P ABC transporter (Permease
MABCCOOD_00335 4.2e-110 tcyB_2 P ABC transporter (permease)
MABCCOOD_00336 2.4e-124 endA F DNA RNA non-specific endonuclease
MABCCOOD_00337 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
MABCCOOD_00338 2.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MABCCOOD_00340 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MABCCOOD_00341 1.6e-34 5.1.3.2 GM Psort location CytoplasmicMembrane, score
MABCCOOD_00342 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MABCCOOD_00343 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MABCCOOD_00345 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MABCCOOD_00346 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MABCCOOD_00347 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MABCCOOD_00348 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
MABCCOOD_00351 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MABCCOOD_00352 3.2e-220 XK27_05110 P chloride
MABCCOOD_00353 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
MABCCOOD_00354 1.3e-282 clcA P Chloride transporter, ClC family
MABCCOOD_00355 2.3e-75 fld C Flavodoxin
MABCCOOD_00357 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
MABCCOOD_00358 3.9e-150 estA CE1 S Putative esterase
MABCCOOD_00359 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MABCCOOD_00360 3.4e-135 XK27_08845 S abc transporter atp-binding protein
MABCCOOD_00361 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
MABCCOOD_00362 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
MABCCOOD_00363 3.2e-17 S Domain of unknown function (DUF4649)
MABCCOOD_00365 4.8e-12 Q the current gene model (or a revised gene model) may contain a frame shift
MABCCOOD_00366 9.4e-14 Q the current gene model (or a revised gene model) may contain a frame shift
MABCCOOD_00367 8.3e-10 Q the current gene model (or a revised gene model) may contain a frame shift
MABCCOOD_00368 9.3e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MABCCOOD_00369 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MABCCOOD_00370 0.0 dnaE 2.7.7.7 L DNA polymerase
MABCCOOD_00371 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
MABCCOOD_00372 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MABCCOOD_00373 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MABCCOOD_00374 2.5e-43 ysdA L Membrane
MABCCOOD_00375 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MABCCOOD_00376 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MABCCOOD_00377 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MABCCOOD_00378 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MABCCOOD_00380 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MABCCOOD_00381 1.7e-83 ypmS S Protein conserved in bacteria
MABCCOOD_00382 6e-144 ypmR E lipolytic protein G-D-S-L family
MABCCOOD_00383 1e-148 DegV S DegV family
MABCCOOD_00384 2.2e-304 recN L May be involved in recombinational repair of damaged DNA
MABCCOOD_00385 3.7e-73 argR K Regulates arginine biosynthesis genes
MABCCOOD_00386 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MABCCOOD_00387 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MABCCOOD_00388 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
MABCCOOD_00389 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MABCCOOD_00392 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MABCCOOD_00393 2.9e-125 dnaD
MABCCOOD_00394 4.6e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MABCCOOD_00395 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MABCCOOD_00396 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
MABCCOOD_00397 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MABCCOOD_00398 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MABCCOOD_00399 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MABCCOOD_00400 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MABCCOOD_00401 3.6e-239 rodA D Belongs to the SEDS family
MABCCOOD_00402 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
MABCCOOD_00403 8e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MABCCOOD_00404 2e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MABCCOOD_00405 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MABCCOOD_00406 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MABCCOOD_00407 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MABCCOOD_00408 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MABCCOOD_00409 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MABCCOOD_00410 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MABCCOOD_00411 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MABCCOOD_00413 1.9e-86 L Integrase core domain protein
MABCCOOD_00414 5.3e-56 L transposition
MABCCOOD_00415 1.8e-21 L Transposase
MABCCOOD_00416 5.2e-36 L transposase activity
MABCCOOD_00417 1.3e-22 XK27_08085
MABCCOOD_00418 5e-71 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MABCCOOD_00419 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MABCCOOD_00420 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MABCCOOD_00421 1e-119 ylfI S tigr01906
MABCCOOD_00422 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MABCCOOD_00423 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
MABCCOOD_00424 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MABCCOOD_00427 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MABCCOOD_00428 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MABCCOOD_00429 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MABCCOOD_00430 6.3e-207 yurR 1.4.5.1 E oxidoreductase
MABCCOOD_00431 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
MABCCOOD_00432 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MABCCOOD_00433 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
MABCCOOD_00434 1.7e-70 gtrA S GtrA-like protein
MABCCOOD_00435 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MABCCOOD_00436 6e-169 ybbR S Protein conserved in bacteria
MABCCOOD_00437 2.8e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MABCCOOD_00438 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
MABCCOOD_00439 8.7e-150 cobQ S glutamine amidotransferase
MABCCOOD_00440 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MABCCOOD_00441 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
MABCCOOD_00442 0.0 uup S abc transporter atp-binding protein
MABCCOOD_00443 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MABCCOOD_00444 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
MABCCOOD_00445 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MABCCOOD_00446 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
MABCCOOD_00447 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MABCCOOD_00448 7.9e-39 ptsH G phosphocarrier protein Hpr
MABCCOOD_00449 7.4e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
MABCCOOD_00450 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
MABCCOOD_00451 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MABCCOOD_00452 2.2e-34 nrdH O Glutaredoxin
MABCCOOD_00453 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MABCCOOD_00454 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MABCCOOD_00456 4.2e-71 L Transposase (IS116 IS110 IS902 family)
MABCCOOD_00457 3.3e-26 L Transposase (IS116 IS110 IS902 family)
MABCCOOD_00458 1.8e-165 ypuA S secreted protein
MABCCOOD_00459 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
MABCCOOD_00460 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
MABCCOOD_00461 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MABCCOOD_00462 2.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MABCCOOD_00463 2.6e-258 noxE P NADH oxidase
MABCCOOD_00464 2.5e-294 yfmM S abc transporter atp-binding protein
MABCCOOD_00465 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
MABCCOOD_00466 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MABCCOOD_00467 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MABCCOOD_00468 2e-86 S ECF-type riboflavin transporter, S component
MABCCOOD_00470 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MABCCOOD_00471 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
MABCCOOD_00473 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MABCCOOD_00474 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MABCCOOD_00475 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MABCCOOD_00476 0.0 smc D Required for chromosome condensation and partitioning
MABCCOOD_00477 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MABCCOOD_00478 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MABCCOOD_00479 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MABCCOOD_00480 4.7e-87 alkD L Dna alkylation repair
MABCCOOD_00481 2.8e-93 pat 2.3.1.183 M acetyltransferase
MABCCOOD_00482 3e-13
MABCCOOD_00483 6.9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MABCCOOD_00484 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MABCCOOD_00485 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
MABCCOOD_00486 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
MABCCOOD_00487 2.8e-149 sdaAA 4.3.1.17 E L-serine dehydratase
MABCCOOD_00488 7.4e-26
MABCCOOD_00489 9.3e-144 S ABC-2 family transporter protein
MABCCOOD_00490 9.5e-98 S transport system, permease component
MABCCOOD_00491 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MABCCOOD_00492 1.5e-192 desK 2.7.13.3 T Histidine kinase
MABCCOOD_00493 1.5e-132 yvfS V ABC-2 type transporter
MABCCOOD_00494 5.7e-158 XK27_09825 V abc transporter atp-binding protein
MABCCOOD_00498 3.3e-212 EGP Major facilitator Superfamily
MABCCOOD_00499 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
MABCCOOD_00500 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
MABCCOOD_00501 4.6e-42 3.6.1.55 F NUDIX domain
MABCCOOD_00503 3.7e-122 S An automated process has identified a potential problem with this gene model
MABCCOOD_00504 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
MABCCOOD_00505 1.4e-15 liaI KT membrane
MABCCOOD_00506 2.6e-30 liaI KT membrane
MABCCOOD_00507 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
MABCCOOD_00508 0.0 V ABC transporter (permease)
MABCCOOD_00509 1.9e-133 macB2 V ABC transporter, ATP-binding protein
MABCCOOD_00510 6.2e-166 T Histidine kinase
MABCCOOD_00511 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MABCCOOD_00512 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MABCCOOD_00513 3.3e-69 pbuX F xanthine permease
MABCCOOD_00514 9.2e-119 pbuX F xanthine permease
MABCCOOD_00515 1.5e-247 norM V Multidrug efflux pump
MABCCOOD_00516 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MABCCOOD_00517 3.5e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
MABCCOOD_00518 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
MABCCOOD_00519 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
MABCCOOD_00520 4.1e-63 yxeN U ABC transporter, permease protein
MABCCOOD_00521 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
MABCCOOD_00522 3e-115 yxeQ S MmgE/PrpD family
MABCCOOD_00523 6e-147 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
MABCCOOD_00524 3e-42 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
MABCCOOD_00525 9.9e-50 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
MABCCOOD_00526 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
MABCCOOD_00527 3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MABCCOOD_00528 4.3e-234 brnQ E Component of the transport system for branched-chain amino acids
MABCCOOD_00529 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
MABCCOOD_00530 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
MABCCOOD_00531 4.8e-25 csbD K CsbD-like
MABCCOOD_00532 6.2e-228 yfnA E amino acid
MABCCOOD_00533 1.9e-109 XK27_02070 S nitroreductase
MABCCOOD_00534 9.5e-150 1.13.11.2 S glyoxalase
MABCCOOD_00535 5.6e-77 ywnA K Transcriptional regulator
MABCCOOD_00536 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
MABCCOOD_00537 5.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MABCCOOD_00538 1.4e-110 drgA C Nitroreductase
MABCCOOD_00539 5e-66 yoaK S Protein of unknown function (DUF1275)
MABCCOOD_00541 6.8e-161 yvgN C reductase
MABCCOOD_00542 1e-181 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MABCCOOD_00543 2.8e-282 XK27_07020 S Belongs to the UPF0371 family
MABCCOOD_00545 1.1e-37 BP1961 P nitric oxide dioxygenase activity
MABCCOOD_00546 1.4e-54 K response regulator
MABCCOOD_00547 9.3e-72 S Signal peptide protein, YSIRK family
MABCCOOD_00549 4.5e-61
MABCCOOD_00550 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MABCCOOD_00551 3.4e-126
MABCCOOD_00552 2.8e-10 IQ PFAM AMP-dependent synthetase and ligase
MABCCOOD_00553 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
MABCCOOD_00554 5.8e-109 MA20_06410 E LysE type translocator
MABCCOOD_00555 5.6e-08
MABCCOOD_00556 2.7e-09
MABCCOOD_00557 0.0 M family 8
MABCCOOD_00559 1.1e-151 V MatE
MABCCOOD_00561 3.9e-110 C Fe-S oxidoreductases
MABCCOOD_00562 1.2e-176 EGP Major Facilitator Superfamily
MABCCOOD_00563 5.5e-258 I radical SAM domain protein
MABCCOOD_00565 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MABCCOOD_00566 1.4e-150 L Integrase core domain protein
MABCCOOD_00567 1.8e-87 L transposase activity
MABCCOOD_00569 2.8e-85
MABCCOOD_00570 0.0 sbcC L ATPase involved in DNA repair
MABCCOOD_00571 2e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MABCCOOD_00572 0.0 lacL 3.2.1.23 G -beta-galactosidase
MABCCOOD_00573 0.0 lacS G transporter
MABCCOOD_00574 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MABCCOOD_00575 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MABCCOOD_00576 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MABCCOOD_00577 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MABCCOOD_00578 2.3e-184 galR K Transcriptional regulator
MABCCOOD_00579 1.2e-25 L transposition
MABCCOOD_00580 3.3e-74 M translation initiation factor activity
MABCCOOD_00581 7.5e-109 M translation initiation factor activity
MABCCOOD_00582 1.4e-67 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
MABCCOOD_00583 1.1e-23 V abc transporter atp-binding protein
MABCCOOD_00584 3e-26 V abc transporter atp-binding protein
MABCCOOD_00585 1.7e-20 V abc transporter atp-binding protein
MABCCOOD_00586 4.3e-40 V abc transporter atp-binding protein
MABCCOOD_00587 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
MABCCOOD_00588 2.3e-87 L Transposase
MABCCOOD_00589 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MABCCOOD_00590 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MABCCOOD_00591 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MABCCOOD_00592 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MABCCOOD_00595 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MABCCOOD_00596 5.8e-175 vraS 2.7.13.3 T Histidine kinase
MABCCOOD_00597 5.4e-119 yvqF KT membrane
MABCCOOD_00598 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MABCCOOD_00599 2e-132 stp 3.1.3.16 T phosphatase
MABCCOOD_00600 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MABCCOOD_00601 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MABCCOOD_00602 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MABCCOOD_00603 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
MABCCOOD_00604 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MABCCOOD_00605 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MABCCOOD_00606 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
MABCCOOD_00607 2.1e-148 supH S overlaps another CDS with the same product name
MABCCOOD_00608 8.6e-63 yvoA_1 K Transcriptional
MABCCOOD_00609 2.8e-120 skfE V abc transporter atp-binding protein
MABCCOOD_00610 3.3e-133 V ATPase activity
MABCCOOD_00611 4.3e-172 oppF P Belongs to the ABC transporter superfamily
MABCCOOD_00612 2.2e-204 oppD P Belongs to the ABC transporter superfamily
MABCCOOD_00613 4.9e-168 amiD P ABC transporter (Permease
MABCCOOD_00614 4.2e-278 amiC P ABC transporter (Permease
MABCCOOD_00615 6.3e-79 amiA E ABC transporter, substrate-binding protein, family 5
MABCCOOD_00616 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MABCCOOD_00617 1.2e-24 oppF P Belongs to the ABC transporter superfamily
MABCCOOD_00618 1.1e-44 oppF P Belongs to the ABC transporter superfamily
MABCCOOD_00619 1.4e-40 tatD L Hydrolase, tatd
MABCCOOD_00620 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
MABCCOOD_00621 1e-110 L Integrase core domain protein
MABCCOOD_00622 1.1e-23 L transposase activity
MABCCOOD_00623 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MABCCOOD_00624 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MABCCOOD_00625 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MABCCOOD_00626 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
MABCCOOD_00627 1.5e-103 yjbK S Adenylate cyclase
MABCCOOD_00628 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MABCCOOD_00629 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
MABCCOOD_00630 2e-58 XK27_04120 S Putative amino acid metabolism
MABCCOOD_00631 3.6e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MABCCOOD_00632 1.6e-131 puuD T peptidase C26
MABCCOOD_00633 4.6e-115 radC E Belongs to the UPF0758 family
MABCCOOD_00634 1.7e-268 M Psort location CytoplasmicMembrane, score
MABCCOOD_00635 0.0 rgpF M Rhamnan synthesis protein F
MABCCOOD_00636 2e-305 GT4 M transferase activity, transferring glycosyl groups
MABCCOOD_00637 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MABCCOOD_00638 2.1e-143 rgpC GM Transport permease protein
MABCCOOD_00639 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
MABCCOOD_00640 1.8e-228 rgpA GT4 M Domain of unknown function (DUF1972)
MABCCOOD_00641 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
MABCCOOD_00642 4.6e-42 S Uncharacterized conserved protein (DUF2304)
MABCCOOD_00643 6.9e-130 arnC M group 2 family protein
MABCCOOD_00644 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
MABCCOOD_00645 9.3e-186 S Glycosyltransferase like family 2
MABCCOOD_00646 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
MABCCOOD_00647 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MABCCOOD_00648 5.3e-237 S Predicted membrane protein (DUF2142)
MABCCOOD_00649 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MABCCOOD_00650 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
MABCCOOD_00651 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MABCCOOD_00652 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MABCCOOD_00653 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MABCCOOD_00654 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
MABCCOOD_00655 1.4e-201 arcT 2.6.1.1 E Aminotransferase
MABCCOOD_00656 2.5e-136 ET ABC transporter
MABCCOOD_00657 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
MABCCOOD_00658 2.9e-84 mutT 3.6.1.55 F Nudix family
MABCCOOD_00659 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MABCCOOD_00661 7.6e-78 S CAAX amino terminal protease family protein
MABCCOOD_00662 7.6e-32 S CAAX amino terminal protease family protein
MABCCOOD_00663 1.5e-253 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MABCCOOD_00664 2.4e-137 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MABCCOOD_00665 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
MABCCOOD_00666 1.1e-16 XK27_00735
MABCCOOD_00667 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MABCCOOD_00669 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MABCCOOD_00672 1.2e-64 paaI Q protein possibly involved in aromatic compounds catabolism
MABCCOOD_00673 3e-37 ycaO O OsmC-like protein
MABCCOOD_00675 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
MABCCOOD_00677 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
MABCCOOD_00678 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MABCCOOD_00679 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MABCCOOD_00680 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MABCCOOD_00681 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
MABCCOOD_00682 1.1e-301 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MABCCOOD_00683 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MABCCOOD_00684 2.6e-109 3.1.3.18 S IA, variant 1
MABCCOOD_00685 2.2e-117 lrgB M effector of murein hydrolase
MABCCOOD_00686 7.7e-56 lrgA S Effector of murein hydrolase LrgA
MABCCOOD_00688 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
MABCCOOD_00689 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
MABCCOOD_00690 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MABCCOOD_00691 3.9e-104 wecD M Acetyltransferase GNAT family
MABCCOOD_00692 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MABCCOOD_00693 5.1e-96 GK ROK family
MABCCOOD_00694 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
MABCCOOD_00695 1.5e-142 XK27_08050 O HflC and HflK could regulate a protease
MABCCOOD_00696 2.3e-206 potD P spermidine putrescine ABC transporter
MABCCOOD_00697 3.3e-133 potC P ABC-type spermidine putrescine transport system, permease component II
MABCCOOD_00698 2.4e-139 potB P ABC-type spermidine putrescine transport system, permease component I
MABCCOOD_00699 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MABCCOOD_00700 7.8e-171 murB 1.3.1.98 M cell wall formation
MABCCOOD_00701 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MABCCOOD_00702 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MABCCOOD_00703 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MABCCOOD_00704 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MABCCOOD_00705 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
MABCCOOD_00706 0.0 ydaO E amino acid
MABCCOOD_00707 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MABCCOOD_00708 4.1e-37 ylqC L Belongs to the UPF0109 family
MABCCOOD_00709 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MABCCOOD_00710 4.5e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
MABCCOOD_00711 2e-157 xth 3.1.11.2 L exodeoxyribonuclease III
MABCCOOD_00712 2.1e-74 S QueT transporter
MABCCOOD_00713 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
MABCCOOD_00714 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
MABCCOOD_00715 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MABCCOOD_00716 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MABCCOOD_00717 2.2e-85 ccl S cog cog4708
MABCCOOD_00718 5.8e-161 rbn E Belongs to the UPF0761 family
MABCCOOD_00719 1.9e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MABCCOOD_00720 3e-232 ytoI K transcriptional regulator containing CBS domains
MABCCOOD_00721 1.1e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
MABCCOOD_00722 1.5e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MABCCOOD_00723 0.0 comEC S Competence protein ComEC
MABCCOOD_00724 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MABCCOOD_00725 1.5e-119 Z012_04635 K Helix-turn-helix XRE-family like proteins
MABCCOOD_00727 2.7e-112 C 4Fe-4S single cluster domain
MABCCOOD_00728 2.5e-139 C Iron-sulfur cluster-binding domain
MABCCOOD_00730 9.2e-156 V AAA domain, putative AbiEii toxin, Type IV TA system
MABCCOOD_00731 2e-55 S ABC-2 type transporter
MABCCOOD_00732 2.8e-97
MABCCOOD_00733 1.1e-23
MABCCOOD_00734 1.9e-141 plsC 2.3.1.51 I Acyltransferase
MABCCOOD_00735 5.4e-79 nodB3 G polysaccharide deacetylase
MABCCOOD_00736 5.9e-48 nodB3 G polysaccharide deacetylase
MABCCOOD_00737 2.7e-140 yabB 2.1.1.223 L Methyltransferase
MABCCOOD_00738 1e-41 yazA L endonuclease containing a URI domain
MABCCOOD_00739 1.3e-237 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MABCCOOD_00740 7.4e-145 corA P CorA-like protein
MABCCOOD_00741 2.5e-62 yjqA S Bacterial PH domain
MABCCOOD_00742 7.8e-100 thiT S Thiamine transporter
MABCCOOD_00743 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MABCCOOD_00744 2.4e-64 yjbB G Permeases of the major facilitator superfamily
MABCCOOD_00745 1.4e-84 yjbB G Permeases of the major facilitator superfamily
MABCCOOD_00746 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MABCCOOD_00747 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
MABCCOOD_00748 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MABCCOOD_00752 1.1e-155 cjaA ET ABC transporter substrate-binding protein
MABCCOOD_00753 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
MABCCOOD_00754 4.6e-115 P ABC transporter (Permease
MABCCOOD_00755 1e-114 papP P ABC transporter (Permease
MABCCOOD_00756 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MABCCOOD_00757 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
MABCCOOD_00758 0.0 copA 3.6.3.54 P P-type ATPase
MABCCOOD_00759 3.2e-74 copY K Copper transport repressor, CopY TcrY family
MABCCOOD_00760 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MABCCOOD_00761 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MABCCOOD_00762 1.4e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
MABCCOOD_00763 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MABCCOOD_00764 3.3e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MABCCOOD_00765 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
MABCCOOD_00766 8.7e-259 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MABCCOOD_00767 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
MABCCOOD_00768 1.4e-54
MABCCOOD_00769 0.0 ctpE P E1-E2 ATPase
MABCCOOD_00770 6.2e-28
MABCCOOD_00771 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MABCCOOD_00772 5.1e-47 L transposase activity
MABCCOOD_00773 1e-128 K transcriptional regulator, MerR family
MABCCOOD_00774 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
MABCCOOD_00775 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
MABCCOOD_00776 1.6e-63 XK27_02560 S cog cog2151
MABCCOOD_00777 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MABCCOOD_00778 7.7e-227 ytfP S Flavoprotein
MABCCOOD_00780 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MABCCOOD_00781 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
MABCCOOD_00782 4.3e-181 ecsB U ABC transporter
MABCCOOD_00783 1.2e-132 ecsA V abc transporter atp-binding protein
MABCCOOD_00784 1.9e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MABCCOOD_00785 2.3e-10
MABCCOOD_00786 2.7e-57 S CD20-like family
MABCCOOD_00787 5.2e-105
MABCCOOD_00788 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
MABCCOOD_00789 6.9e-206 ylbM S Belongs to the UPF0348 family
MABCCOOD_00790 2e-140 yqeM Q Methyltransferase domain protein
MABCCOOD_00791 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MABCCOOD_00792 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MABCCOOD_00793 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MABCCOOD_00794 3.5e-49 yhbY J RNA-binding protein
MABCCOOD_00795 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MABCCOOD_00796 1.8e-98 yqeG S hydrolase of the HAD superfamily
MABCCOOD_00797 1.3e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MABCCOOD_00798 1.3e-57
MABCCOOD_00799 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MABCCOOD_00800 1.7e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MABCCOOD_00801 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MABCCOOD_00802 1.5e-258 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MABCCOOD_00803 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MABCCOOD_00804 4.8e-154 hlpA M Belongs to the NlpA lipoprotein family
MABCCOOD_00805 6.8e-101 pncA Q isochorismatase
MABCCOOD_00806 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MABCCOOD_00807 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
MABCCOOD_00808 2.4e-75 XK27_03180 T universal stress protein
MABCCOOD_00811 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MABCCOOD_00812 7.1e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
MABCCOOD_00813 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
MABCCOOD_00814 0.0 yjcE P NhaP-type Na H and K H antiporters
MABCCOOD_00816 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
MABCCOOD_00817 1.3e-184 yhcC S radical SAM protein
MABCCOOD_00818 2.2e-196 ylbL T Belongs to the peptidase S16 family
MABCCOOD_00819 5.9e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MABCCOOD_00820 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
MABCCOOD_00821 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MABCCOOD_00822 1.9e-09 S Protein of unknown function (DUF4059)
MABCCOOD_00823 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
MABCCOOD_00824 1e-162 yxeN P ABC transporter (Permease
MABCCOOD_00825 2.6e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MABCCOOD_00827 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MABCCOOD_00828 0.0 pflB 2.3.1.54 C formate acetyltransferase'
MABCCOOD_00829 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
MABCCOOD_00830 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MABCCOOD_00831 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
MABCCOOD_00832 2.9e-87 D nuclear chromosome segregation
MABCCOOD_00833 1.5e-127 ybbM S transport system, permease component
MABCCOOD_00834 1.2e-117 ybbL S abc transporter atp-binding protein
MABCCOOD_00835 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
MABCCOOD_00836 4.6e-140 cppA E CppA N-terminal
MABCCOOD_00837 5e-44 V CAAX protease self-immunity
MABCCOOD_00838 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MABCCOOD_00839 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MABCCOOD_00842 3e-47 spiA K sequence-specific DNA binding
MABCCOOD_00843 9.5e-140 blpT
MABCCOOD_00847 9.1e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
MABCCOOD_00848 8.2e-70 argR K Regulates arginine biosynthesis genes
MABCCOOD_00849 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MABCCOOD_00850 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MABCCOOD_00851 7e-34 S Protein of unknown function (DUF3021)
MABCCOOD_00852 1.2e-61 KT phosphorelay signal transduction system
MABCCOOD_00854 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MABCCOOD_00856 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MABCCOOD_00857 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
MABCCOOD_00858 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
MABCCOOD_00859 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MABCCOOD_00860 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
MABCCOOD_00861 1.4e-59 L integrase core domain
MABCCOOD_00866 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
MABCCOOD_00870 7.4e-135 agrA KT phosphorelay signal transduction system
MABCCOOD_00871 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
MABCCOOD_00873 7.3e-237 mesE M Transport protein ComB
MABCCOOD_00874 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MABCCOOD_00875 0.0 mdlB V abc transporter atp-binding protein
MABCCOOD_00876 0.0 mdlA V abc transporter atp-binding protein
MABCCOOD_00878 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
MABCCOOD_00879 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MABCCOOD_00880 3.6e-70 yutD J protein conserved in bacteria
MABCCOOD_00881 5.1e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MABCCOOD_00883 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MABCCOOD_00884 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MABCCOOD_00885 0.0 ftsI 3.4.16.4 M penicillin-binding protein
MABCCOOD_00886 4.3e-47 ftsL D cell division protein FtsL
MABCCOOD_00887 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MABCCOOD_00888 3e-128
MABCCOOD_00889 9.7e-32 yhaI J Protein of unknown function (DUF805)
MABCCOOD_00890 1.3e-08 D nuclear chromosome segregation
MABCCOOD_00891 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MABCCOOD_00892 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MABCCOOD_00893 2.2e-285 XK27_00765
MABCCOOD_00894 8.1e-134 ecsA_2 V abc transporter atp-binding protein
MABCCOOD_00895 5.2e-125 S Protein of unknown function (DUF554)
MABCCOOD_00896 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MABCCOOD_00897 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MABCCOOD_00898 2.6e-121 liaI S membrane
MABCCOOD_00899 5.2e-75 XK27_02470 K LytTr DNA-binding domain
MABCCOOD_00900 3.6e-66 KT response to antibiotic
MABCCOOD_00901 2e-80 yebC M Membrane
MABCCOOD_00902 2.9e-18 yebC M Membrane
MABCCOOD_00903 2.8e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
MABCCOOD_00904 2.2e-179 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MABCCOOD_00905 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MABCCOOD_00906 6.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MABCCOOD_00907 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MABCCOOD_00908 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MABCCOOD_00909 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MABCCOOD_00910 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MABCCOOD_00912 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
MABCCOOD_00913 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
MABCCOOD_00914 0.0 scrA 2.7.1.211 G pts system
MABCCOOD_00915 5.4e-291 scrB 3.2.1.26 GH32 G invertase
MABCCOOD_00916 7.5e-180 scrR K Transcriptional
MABCCOOD_00917 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MABCCOOD_00918 3.4e-62 yqhY S protein conserved in bacteria
MABCCOOD_00919 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MABCCOOD_00920 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
MABCCOOD_00921 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
MABCCOOD_00923 8e-44 V 'abc transporter, ATP-binding protein
MABCCOOD_00924 1e-58 V 'abc transporter, ATP-binding protein
MABCCOOD_00927 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MABCCOOD_00928 2e-169 corA P COG0598 Mg2 and Co2 transporters
MABCCOOD_00929 3.1e-124 XK27_01040 S Pfam PF06570
MABCCOOD_00931 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MABCCOOD_00932 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MABCCOOD_00933 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
MABCCOOD_00934 3.6e-41 XK27_05745
MABCCOOD_00935 9.5e-230 mutY L A G-specific adenine glycosylase
MABCCOOD_00940 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MABCCOOD_00941 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MABCCOOD_00942 1e-93 cvpA S toxin biosynthetic process
MABCCOOD_00943 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MABCCOOD_00944 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MABCCOOD_00945 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MABCCOOD_00946 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MABCCOOD_00947 8.8e-48 azlD E branched-chain amino acid
MABCCOOD_00948 2.5e-116 azlC E AzlC protein
MABCCOOD_00949 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MABCCOOD_00950 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MABCCOOD_00951 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
MABCCOOD_00952 2.5e-33 ykzG S Belongs to the UPF0356 family
MABCCOOD_00953 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MABCCOOD_00954 2.7e-40 pscB M CHAP domain protein
MABCCOOD_00955 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
MABCCOOD_00956 8.5e-63 glnR K Transcriptional regulator
MABCCOOD_00957 1.3e-87 S Fusaric acid resistance protein-like
MABCCOOD_00958 1.1e-12
MABCCOOD_00959 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MABCCOOD_00960 3.2e-42 L Transposase
MABCCOOD_00961 1.9e-46 L transposase activity
MABCCOOD_00962 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MABCCOOD_00963 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MABCCOOD_00964 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MABCCOOD_00965 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MABCCOOD_00966 1.1e-142 purR 2.4.2.7 F operon repressor
MABCCOOD_00967 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
MABCCOOD_00968 6.9e-173 rmuC S RmuC domain protein
MABCCOOD_00969 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
MABCCOOD_00970 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MABCCOOD_00971 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MABCCOOD_00973 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MABCCOOD_00974 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MABCCOOD_00975 2.2e-142 tatD L Hydrolase, tatd
MABCCOOD_00976 2.5e-74 yccU S CoA-binding protein
MABCCOOD_00977 4.8e-51 trxA O Belongs to the thioredoxin family
MABCCOOD_00978 7.8e-143 S Macro domain protein
MABCCOOD_00979 3.1e-10 L thioesterase
MABCCOOD_00980 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
MABCCOOD_00983 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MABCCOOD_00984 5e-84 L Transposase
MABCCOOD_00985 1e-13 rpmH J Ribosomal protein L34
MABCCOOD_00986 5.5e-184 jag S RNA-binding protein
MABCCOOD_00987 1.7e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MABCCOOD_00988 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MABCCOOD_00989 5.4e-264 argH 4.3.2.1 E Argininosuccinate lyase
MABCCOOD_00990 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MABCCOOD_00991 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MABCCOOD_00992 6.7e-81 amiA E transmembrane transport
MABCCOOD_00993 2e-41 amiA E transmembrane transport
MABCCOOD_00994 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
MABCCOOD_00995 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
MABCCOOD_00996 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MABCCOOD_00997 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MABCCOOD_00998 9.2e-51 S Protein of unknown function (DUF3397)
MABCCOOD_00999 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MABCCOOD_01000 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
MABCCOOD_01001 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
MABCCOOD_01002 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
MABCCOOD_01003 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MABCCOOD_01004 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MABCCOOD_01005 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
MABCCOOD_01006 4.3e-77 XK27_09620 S reductase
MABCCOOD_01007 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
MABCCOOD_01008 4.4e-117 XK27_09615 C reductase
MABCCOOD_01009 8.1e-91 fnt P Formate nitrite transporter
MABCCOOD_01010 6.5e-83 XK27_08585 S Psort location CytoplasmicMembrane, score
MABCCOOD_01011 7.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MABCCOOD_01012 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MABCCOOD_01013 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MABCCOOD_01014 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MABCCOOD_01015 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MABCCOOD_01016 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MABCCOOD_01017 6e-48 S glycolate biosynthetic process
MABCCOOD_01018 1.5e-64 S phosphatase activity
MABCCOOD_01019 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
MABCCOOD_01022 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MABCCOOD_01023 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MABCCOOD_01024 8.3e-37 yeeD O sulfur carrier activity
MABCCOOD_01025 7.8e-191 yeeE S Sulphur transport
MABCCOOD_01026 1.8e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MABCCOOD_01027 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MABCCOOD_01028 1.2e-08 S Domain of unknown function (DUF4651)
MABCCOOD_01029 5.7e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MABCCOOD_01030 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MABCCOOD_01031 3.9e-111 S CAAX amino terminal protease family protein
MABCCOOD_01033 5e-67 V CAAX protease self-immunity
MABCCOOD_01034 1.4e-33 V CAAX protease self-immunity
MABCCOOD_01035 8.8e-27 lanR K sequence-specific DNA binding
MABCCOOD_01036 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MABCCOOD_01037 4.2e-175 ytxK 2.1.1.72 L DNA methylase
MABCCOOD_01038 2.2e-11 comGF U Putative Competence protein ComGF
MABCCOOD_01039 1.3e-70 comGF U Competence protein ComGF
MABCCOOD_01040 1.4e-15 NU Type II secretory pathway pseudopilin
MABCCOOD_01041 2.6e-56 cglD NU Competence protein
MABCCOOD_01042 2.5e-42 comGC U Required for transformation and DNA binding
MABCCOOD_01043 5.4e-153 cglB U protein transport across the cell outer membrane
MABCCOOD_01044 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MABCCOOD_01045 3.2e-67 S cog cog4699
MABCCOOD_01046 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MABCCOOD_01047 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MABCCOOD_01048 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MABCCOOD_01049 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MABCCOOD_01050 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MABCCOOD_01051 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
MABCCOOD_01052 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
MABCCOOD_01053 1.6e-249 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MABCCOOD_01054 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MABCCOOD_01055 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
MABCCOOD_01056 1.8e-57 asp S cog cog1302
MABCCOOD_01057 3.2e-226 norN V Mate efflux family protein
MABCCOOD_01058 1.9e-278 thrC 4.2.3.1 E Threonine synthase
MABCCOOD_01059 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MABCCOOD_01060 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
MABCCOOD_01061 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MABCCOOD_01062 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MABCCOOD_01063 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
MABCCOOD_01064 0.0 pepO 3.4.24.71 O Peptidase family M13
MABCCOOD_01065 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MABCCOOD_01066 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MABCCOOD_01067 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MABCCOOD_01068 1.4e-54 treB 2.7.1.201 G PTS System
MABCCOOD_01069 5.8e-21 treR K DNA-binding transcription factor activity
MABCCOOD_01070 1.2e-85 treR K trehalose operon
MABCCOOD_01071 3.3e-95 ywlG S Belongs to the UPF0340 family
MABCCOOD_01073 2.7e-13 L PFAM Integrase, catalytic core
MABCCOOD_01074 4.2e-72 L PFAM Integrase, catalytic core
MABCCOOD_01075 4.9e-102 L Transposase
MABCCOOD_01076 1.9e-13
MABCCOOD_01077 1.3e-298 hsdM 2.1.1.72 V HsdM N-terminal domain
MABCCOOD_01078 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MABCCOOD_01079 6.4e-24
MABCCOOD_01080 1e-140 L DNA integration
MABCCOOD_01081 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
MABCCOOD_01083 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
MABCCOOD_01084 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
MABCCOOD_01085 2.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
MABCCOOD_01086 1.9e-33 L PFAM Integrase, catalytic core
MABCCOOD_01087 2.1e-115 L PFAM Integrase, catalytic core
MABCCOOD_01088 3.3e-62 rplQ J ribosomal protein l17
MABCCOOD_01089 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MABCCOOD_01090 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MABCCOOD_01091 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MABCCOOD_01092 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MABCCOOD_01093 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MABCCOOD_01094 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MABCCOOD_01095 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MABCCOOD_01096 7.4e-58 rplO J binds to the 23S rRNA
MABCCOOD_01097 2.5e-23 rpmD J ribosomal protein l30
MABCCOOD_01098 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MABCCOOD_01099 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MABCCOOD_01100 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MABCCOOD_01101 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MABCCOOD_01102 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MABCCOOD_01103 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MABCCOOD_01104 4.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MABCCOOD_01105 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MABCCOOD_01106 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MABCCOOD_01107 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MABCCOOD_01108 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MABCCOOD_01109 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MABCCOOD_01110 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MABCCOOD_01111 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MABCCOOD_01112 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MABCCOOD_01113 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MABCCOOD_01114 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
MABCCOOD_01115 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MABCCOOD_01116 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MABCCOOD_01117 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MABCCOOD_01118 0.0 XK27_09800 I Acyltransferase
MABCCOOD_01119 1.7e-35 XK27_09805 S MORN repeat protein
MABCCOOD_01120 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MABCCOOD_01121 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MABCCOOD_01122 8.8e-83 adk 2.7.4.3 F topology modulation protein
MABCCOOD_01123 3.1e-172 yxaM EGP Major facilitator Superfamily
MABCCOOD_01124 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
MABCCOOD_01126 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MABCCOOD_01127 0.0 KLT serine threonine protein kinase
MABCCOOD_01128 2.1e-280 V ABC transporter
MABCCOOD_01129 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MABCCOOD_01130 7e-127 Z012_04635 K sequence-specific DNA binding
MABCCOOD_01132 1.6e-53 C Radical SAM
MABCCOOD_01133 1.3e-159 C Radical SAM
MABCCOOD_01134 5.1e-287 V ABC transporter transmembrane region
MABCCOOD_01135 2.5e-89 K sequence-specific DNA binding
MABCCOOD_01136 2.2e-132 int L Belongs to the 'phage' integrase family
MABCCOOD_01138 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
MABCCOOD_01139 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MABCCOOD_01140 2.8e-44 yrzL S Belongs to the UPF0297 family
MABCCOOD_01141 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MABCCOOD_01142 4.2e-44 yrzB S Belongs to the UPF0473 family
MABCCOOD_01143 4e-298 ccs S the current gene model (or a revised gene model) may contain a frame shift
MABCCOOD_01144 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MABCCOOD_01145 7.5e-14
MABCCOOD_01146 2.6e-91 XK27_10930 K acetyltransferase
MABCCOOD_01147 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MABCCOOD_01148 4.1e-147 yaaA S Belongs to the UPF0246 family
MABCCOOD_01149 2.7e-166 XK27_01785 S cog cog1284
MABCCOOD_01150 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MABCCOOD_01152 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
MABCCOOD_01153 3e-53 metE 2.1.1.14 E Methionine synthase
MABCCOOD_01154 4.4e-54 metE 2.1.1.14 E Methionine synthase
MABCCOOD_01155 1.4e-36 metE 2.1.1.14 E Methionine synthase
MABCCOOD_01156 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MABCCOOD_01157 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MABCCOOD_01159 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
MABCCOOD_01160 2.7e-95 S Hydrophobic domain protein
MABCCOOD_01162 3.7e-27 S Membrane
MABCCOOD_01163 3.1e-101
MABCCOOD_01164 1.8e-23 S Small integral membrane protein
MABCCOOD_01165 1.1e-71 M Protein conserved in bacteria
MABCCOOD_01166 4.9e-12 K CsbD-like
MABCCOOD_01167 7.2e-95 nudL L hydrolase
MABCCOOD_01168 3.4e-13 nudL L hydrolase
MABCCOOD_01169 4e-19 K negative regulation of transcription, DNA-templated
MABCCOOD_01170 1.7e-23 K negative regulation of transcription, DNA-templated
MABCCOOD_01172 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
MABCCOOD_01173 1.8e-88 S Putative adhesin
MABCCOOD_01174 3.9e-161 XK27_06930 V domain protein
MABCCOOD_01175 6.4e-96 XK27_06935 K transcriptional regulator
MABCCOOD_01176 4.8e-55 ypaA M Membrane
MABCCOOD_01177 2e-07
MABCCOOD_01178 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MABCCOOD_01179 8.2e-48 veg S Biofilm formation stimulator VEG
MABCCOOD_01180 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MABCCOOD_01181 3.9e-70 rplI J binds to the 23S rRNA
MABCCOOD_01182 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MABCCOOD_01183 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MABCCOOD_01184 2.1e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MABCCOOD_01185 0.0 S Bacterial membrane protein, YfhO
MABCCOOD_01186 5e-61 isaA GH23 M Immunodominant staphylococcal antigen A
MABCCOOD_01187 5.3e-85 lytE M LysM domain protein
MABCCOOD_01188 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MABCCOOD_01189 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MABCCOOD_01190 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MABCCOOD_01191 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MABCCOOD_01192 1.8e-137 ymfM S sequence-specific DNA binding
MABCCOOD_01193 1.5e-178 ymfH S Peptidase M16
MABCCOOD_01194 4e-38 ymfH S Peptidase M16
MABCCOOD_01195 4e-234 ymfF S Peptidase M16
MABCCOOD_01196 1.6e-45 yaaA S S4 domain protein YaaA
MABCCOOD_01197 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MABCCOOD_01198 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MABCCOOD_01199 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MABCCOOD_01200 4.2e-153 yvjA S membrane
MABCCOOD_01201 6.7e-306 ybiT S abc transporter atp-binding protein
MABCCOOD_01202 0.0 XK27_10405 S Bacterial membrane protein YfhO
MABCCOOD_01206 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
MABCCOOD_01207 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MABCCOOD_01208 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
MABCCOOD_01209 8.5e-134 parB K Belongs to the ParB family
MABCCOOD_01210 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MABCCOOD_01211 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MABCCOOD_01212 1.1e-29 yyzM S Protein conserved in bacteria
MABCCOOD_01213 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MABCCOOD_01214 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MABCCOOD_01215 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MABCCOOD_01216 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MABCCOOD_01217 2.7e-61 divIC D Septum formation initiator
MABCCOOD_01219 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
MABCCOOD_01220 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MABCCOOD_01221 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MABCCOOD_01222 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MABCCOOD_01223 1.1e-136 L Transposase
MABCCOOD_01224 2.2e-50 3.1.21.3 V Type I restriction modification DNA specificity domain
MABCCOOD_01225 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MABCCOOD_01226 4.5e-61 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
MABCCOOD_01227 5.7e-46 S Domain of unknown function (DUF4298)
MABCCOOD_01228 4.1e-66 L Integrase
MABCCOOD_01230 1.1e-154 L Replication protein
MABCCOOD_01231 3.9e-136 3.1.21.3 V Type I restriction modification DNA specificity domain
MABCCOOD_01234 1.9e-07
MABCCOOD_01239 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MABCCOOD_01240 8.9e-234 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MABCCOOD_01241 5.5e-36 XK27_02060 S Transglycosylase associated protein
MABCCOOD_01242 2.6e-55 badR K DNA-binding transcription factor activity
MABCCOOD_01243 3.5e-97 S reductase
MABCCOOD_01244 6.9e-89 L Integrase core domain protein
MABCCOOD_01245 6.4e-41 L transposition
MABCCOOD_01247 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
MABCCOOD_01248 4.6e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MABCCOOD_01250 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
MABCCOOD_01251 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MABCCOOD_01252 1.1e-83 S Putative small multi-drug export protein
MABCCOOD_01253 6.2e-76 ctsR K Belongs to the CtsR family
MABCCOOD_01254 0.0 clpC O Belongs to the ClpA ClpB family
MABCCOOD_01255 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MABCCOOD_01256 2e-59 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MABCCOOD_01257 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MABCCOOD_01258 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MABCCOOD_01259 6.9e-144 S SseB protein N-terminal domain
MABCCOOD_01260 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
MABCCOOD_01261 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MABCCOOD_01262 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MABCCOOD_01265 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MABCCOOD_01266 3.5e-91 yacP S RNA-binding protein containing a PIN domain
MABCCOOD_01267 3.4e-155 degV S DegV family
MABCCOOD_01268 1.8e-31 K helix-turn-helix
MABCCOOD_01269 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MABCCOOD_01270 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MABCCOOD_01271 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MABCCOOD_01272 1.5e-35 K sequence-specific DNA binding
MABCCOOD_01274 0.0 S Lantibiotic dehydratase, C terminus
MABCCOOD_01275 2.4e-231 spaC2 V Lanthionine synthetase C family protein
MABCCOOD_01276 5.6e-183 EGP Major facilitator Superfamily
MABCCOOD_01277 5.9e-24 3.6.4.12
MABCCOOD_01278 5.9e-91 3.6.4.12 K Divergent AAA domain protein
MABCCOOD_01279 8.2e-224 int L Belongs to the 'phage' integrase family
MABCCOOD_01280 1.8e-38 S Helix-turn-helix domain
MABCCOOD_01281 4.9e-173
MABCCOOD_01283 6.3e-74 isp2 S pathogenesis
MABCCOOD_01284 6.2e-128 tnp L Transposase IS66 family
MABCCOOD_01285 3.3e-225 capA M Bacterial capsule synthesis protein
MABCCOOD_01286 3.6e-39 gcvR T UPF0237 protein
MABCCOOD_01287 1.9e-242 XK27_08635 S UPF0210 protein
MABCCOOD_01288 2.2e-38 ais G alpha-ribazole phosphatase activity
MABCCOOD_01289 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MABCCOOD_01290 1.3e-102 acmA 3.2.1.17 NU amidase activity
MABCCOOD_01291 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MABCCOOD_01292 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MABCCOOD_01293 7.5e-298 dnaK O Heat shock 70 kDa protein
MABCCOOD_01294 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MABCCOOD_01295 8.5e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MABCCOOD_01296 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
MABCCOOD_01297 1.7e-60 hmpT S membrane
MABCCOOD_01299 9.9e-19 S Domain of unknown function (DUF4649)
MABCCOOD_01300 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
MABCCOOD_01301 2.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MABCCOOD_01302 6.5e-87
MABCCOOD_01303 1.6e-77 sigH K DNA-templated transcription, initiation
MABCCOOD_01304 3e-148 ykuT M mechanosensitive ion channel
MABCCOOD_01305 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MABCCOOD_01306 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MABCCOOD_01307 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MABCCOOD_01308 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
MABCCOOD_01309 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
MABCCOOD_01310 5.9e-177 prmA J Ribosomal protein L11 methyltransferase
MABCCOOD_01311 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MABCCOOD_01312 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MABCCOOD_01313 2.4e-83 nrdI F Belongs to the NrdI family
MABCCOOD_01314 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MABCCOOD_01315 7.4e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MABCCOOD_01316 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MABCCOOD_01317 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MABCCOOD_01318 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MABCCOOD_01319 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MABCCOOD_01320 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MABCCOOD_01321 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MABCCOOD_01322 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MABCCOOD_01323 6.5e-202 yhjX P Major Facilitator
MABCCOOD_01324 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MABCCOOD_01325 5e-94 V VanZ like family
MABCCOOD_01327 1e-123 glnQ E abc transporter atp-binding protein
MABCCOOD_01328 1.8e-276 glnP P ABC transporter
MABCCOOD_01329 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MABCCOOD_01330 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MABCCOOD_01331 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
MABCCOOD_01332 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MABCCOOD_01333 6.3e-235 sufD O assembly protein SufD
MABCCOOD_01334 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MABCCOOD_01335 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
MABCCOOD_01336 2.2e-273 sufB O assembly protein SufB
MABCCOOD_01337 7e-10 oppA E ABC transporter substrate-binding protein
MABCCOOD_01338 3.3e-138 oppA E ABC transporter substrate-binding protein
MABCCOOD_01339 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MABCCOOD_01340 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MABCCOOD_01341 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MABCCOOD_01342 9.8e-40 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MABCCOOD_01343 3e-27 oppD P Belongs to the ABC transporter superfamily
MABCCOOD_01344 2.5e-32 oppD P Belongs to the ABC transporter superfamily
MABCCOOD_01345 1.7e-61 oppD P Belongs to the ABC transporter superfamily
MABCCOOD_01346 3.1e-43 oppD P Belongs to the ABC transporter superfamily
MABCCOOD_01347 1.1e-60 oppF P Belongs to the ABC transporter superfamily
MABCCOOD_01348 1.2e-91 oppF P Belongs to the ABC transporter superfamily
MABCCOOD_01351 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MABCCOOD_01352 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MABCCOOD_01353 4.9e-222 EGP Major facilitator Superfamily
MABCCOOD_01354 3.1e-72 adcR K transcriptional
MABCCOOD_01355 2.2e-136 adcC P ABC transporter, ATP-binding protein
MABCCOOD_01356 4.6e-130 adcB P ABC transporter (Permease
MABCCOOD_01357 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MABCCOOD_01358 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
MABCCOOD_01359 7.8e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
MABCCOOD_01360 1.4e-105 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MABCCOOD_01361 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
MABCCOOD_01362 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
MABCCOOD_01363 1.9e-127 yeeN K transcriptional regulatory protein
MABCCOOD_01364 9.8e-50 yajC U protein transport
MABCCOOD_01365 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MABCCOOD_01366 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
MABCCOOD_01367 5.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MABCCOOD_01368 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MABCCOOD_01369 0.0 WQ51_06230 S ABC transporter substrate binding protein
MABCCOOD_01370 5.2e-142 cmpC S abc transporter atp-binding protein
MABCCOOD_01371 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MABCCOOD_01372 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MABCCOOD_01373 4.4e-37 L Transposase
MABCCOOD_01374 6.4e-18 L transposase activity
MABCCOOD_01377 4.7e-43
MABCCOOD_01378 3.4e-55 S TM2 domain
MABCCOOD_01379 1.8e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MABCCOOD_01380 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MABCCOOD_01381 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
MABCCOOD_01382 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
MABCCOOD_01383 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
MABCCOOD_01384 1.7e-45 cof Q phosphatase activity
MABCCOOD_01385 1.9e-31 cof Q phosphatase activity
MABCCOOD_01386 7.3e-83 glcR K transcriptional regulator (DeoR family)
MABCCOOD_01387 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MABCCOOD_01388 3.5e-71 K transcriptional
MABCCOOD_01389 2.2e-232 S COG1073 Hydrolases of the alpha beta superfamily
MABCCOOD_01390 3.4e-277 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MABCCOOD_01391 4.8e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MABCCOOD_01392 3.2e-77 yhaI L Membrane
MABCCOOD_01393 1.7e-259 pepC 3.4.22.40 E aminopeptidase
MABCCOOD_01394 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MABCCOOD_01395 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MABCCOOD_01396 3.1e-95 ypsA S Belongs to the UPF0398 family
MABCCOOD_01397 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MABCCOOD_01398 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MABCCOOD_01399 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
MABCCOOD_01400 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
MABCCOOD_01401 2.5e-23
MABCCOOD_01402 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MABCCOOD_01403 7.3e-80 XK27_09675 K -acetyltransferase
MABCCOOD_01404 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MABCCOOD_01405 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MABCCOOD_01406 5.2e-59 L Integrase core domain protein
MABCCOOD_01407 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MABCCOOD_01408 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MABCCOOD_01409 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MABCCOOD_01410 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
MABCCOOD_01411 1.5e-97 ybhL S Belongs to the BI1 family
MABCCOOD_01414 2.8e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MABCCOOD_01415 1.4e-90 K transcriptional regulator
MABCCOOD_01416 7.6e-36 yneF S UPF0154 protein
MABCCOOD_01417 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MABCCOOD_01418 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MABCCOOD_01419 3.5e-99 XK27_09740 S Phosphoesterase
MABCCOOD_01420 5.4e-86 ykuL S CBS domain
MABCCOOD_01421 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
MABCCOOD_01422 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MABCCOOD_01423 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MABCCOOD_01424 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MABCCOOD_01425 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MABCCOOD_01426 1.2e-258 trkH P Cation transport protein
MABCCOOD_01427 1.5e-247 trkA P Potassium transporter peripheral membrane component
MABCCOOD_01428 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MABCCOOD_01429 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MABCCOOD_01430 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
MABCCOOD_01431 9.5e-161 K sequence-specific DNA binding
MABCCOOD_01432 1.9e-33 V protein secretion by the type I secretion system
MABCCOOD_01433 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MABCCOOD_01434 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MABCCOOD_01435 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MABCCOOD_01436 3.7e-22 yhaI L Membrane
MABCCOOD_01437 1.4e-54 S Domain of unknown function (DUF4173)
MABCCOOD_01438 6.8e-95 ureI S AmiS/UreI family transporter
MABCCOOD_01439 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MABCCOOD_01440 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MABCCOOD_01441 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MABCCOOD_01442 6.6e-78 ureE O enzyme active site formation
MABCCOOD_01443 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MABCCOOD_01444 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MABCCOOD_01445 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MABCCOOD_01446 2.7e-177 cbiM P PDGLE domain
MABCCOOD_01447 1.1e-136 P cobalt transport protein
MABCCOOD_01448 1.6e-131 cbiO P ABC transporter
MABCCOOD_01449 5.3e-153 ET amino acid transport
MABCCOOD_01450 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MABCCOOD_01451 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
MABCCOOD_01452 3.8e-205 EGP Transmembrane secretion effector
MABCCOOD_01453 4e-153 ET amino acid transport
MABCCOOD_01454 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
MABCCOOD_01455 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MABCCOOD_01456 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
MABCCOOD_01457 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
MABCCOOD_01458 9.8e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MABCCOOD_01459 8.8e-98 metI P ABC transporter (Permease
MABCCOOD_01460 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MABCCOOD_01461 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MABCCOOD_01462 8e-94 S UPF0397 protein
MABCCOOD_01463 0.0 ykoD P abc transporter atp-binding protein
MABCCOOD_01464 1.2e-149 cbiQ P cobalt transport
MABCCOOD_01465 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MABCCOOD_01466 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
MABCCOOD_01467 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
MABCCOOD_01468 1.5e-242 P COG0168 Trk-type K transport systems, membrane components
MABCCOOD_01469 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
MABCCOOD_01470 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
MABCCOOD_01471 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MABCCOOD_01472 2.8e-282 T PhoQ Sensor
MABCCOOD_01473 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MABCCOOD_01474 6.5e-218 dnaB L Replication initiation and membrane attachment
MABCCOOD_01475 5.2e-167 dnaI L Primosomal protein DnaI
MABCCOOD_01476 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MABCCOOD_01478 1.2e-34
MABCCOOD_01479 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
MABCCOOD_01480 3e-27 L Integrase core domain protein
MABCCOOD_01481 1.4e-51 L transposition
MABCCOOD_01482 5e-17 L Transposase
MABCCOOD_01483 2.7e-61 L Transposase
MABCCOOD_01484 2.8e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MABCCOOD_01485 6.5e-63 manO S protein conserved in bacteria
MABCCOOD_01486 1.9e-169 manN G PTS system mannose fructose sorbose family IID component
MABCCOOD_01487 1.6e-117 manM G pts system
MABCCOOD_01488 1.3e-174 manL 2.7.1.191 G pts system
MABCCOOD_01489 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
MABCCOOD_01490 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MABCCOOD_01491 1.9e-248 pbuO S permease
MABCCOOD_01492 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
MABCCOOD_01493 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
MABCCOOD_01494 1.2e-219 brpA K Transcriptional
MABCCOOD_01495 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
MABCCOOD_01496 3.1e-212 nusA K Participates in both transcription termination and antitermination
MABCCOOD_01497 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
MABCCOOD_01498 1.4e-41 ylxQ J ribosomal protein
MABCCOOD_01499 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MABCCOOD_01500 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MABCCOOD_01501 1.8e-45 yvdD 3.2.2.10 S Belongs to the LOG family
MABCCOOD_01503 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
MABCCOOD_01504 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
MABCCOOD_01505 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MABCCOOD_01506 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
MABCCOOD_01507 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
MABCCOOD_01508 1.8e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
MABCCOOD_01509 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MABCCOOD_01511 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MABCCOOD_01512 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MABCCOOD_01513 3.4e-74 ylbF S Belongs to the UPF0342 family
MABCCOOD_01514 7.1e-46 ylbG S UPF0298 protein
MABCCOOD_01515 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MABCCOOD_01516 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
MABCCOOD_01517 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
MABCCOOD_01518 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MABCCOOD_01519 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MABCCOOD_01520 2.8e-70 acuB S IMP dehydrogenase activity
MABCCOOD_01521 3.3e-43 acuB S IMP dehydrogenase activity
MABCCOOD_01522 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MABCCOOD_01523 6.3e-111 yvyE 3.4.13.9 S YigZ family
MABCCOOD_01524 5.3e-253 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MABCCOOD_01525 1.7e-122 comFC S Competence protein
MABCCOOD_01526 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MABCCOOD_01533 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
MABCCOOD_01534 6.4e-108 S Domain of unknown function (DUF1803)
MABCCOOD_01535 7.8e-102 ygaC J Belongs to the UPF0374 family
MABCCOOD_01536 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
MABCCOOD_01537 1.5e-258 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MABCCOOD_01538 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
MABCCOOD_01539 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
MABCCOOD_01540 1.9e-115 S Haloacid dehalogenase-like hydrolase
MABCCOOD_01541 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MABCCOOD_01542 4e-72 marR K Transcriptional regulator, MarR family
MABCCOOD_01543 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MABCCOOD_01544 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MABCCOOD_01545 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
MABCCOOD_01546 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MABCCOOD_01547 1.6e-126 IQ reductase
MABCCOOD_01548 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MABCCOOD_01549 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MABCCOOD_01550 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MABCCOOD_01551 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MABCCOOD_01552 1.7e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MABCCOOD_01553 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MABCCOOD_01554 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MABCCOOD_01555 9.9e-64 tnp L Transposase
MABCCOOD_01556 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
MABCCOOD_01557 2.8e-175 gadC E Psort location CytoplasmicMembrane, score 10.00
MABCCOOD_01559 1.3e-07 L Transposase and inactivated derivatives, TnpA family
MABCCOOD_01560 3.4e-126 tnp L Transposase
MABCCOOD_01561 4.9e-47 tnp L Transposase
MABCCOOD_01562 2.1e-206 rny D Endoribonuclease that initiates mRNA decay
MABCCOOD_01563 2.4e-84 L Transposase
MABCCOOD_01564 2.1e-113 fruR K transcriptional
MABCCOOD_01565 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MABCCOOD_01566 0.0 fruA 2.7.1.202 G phosphotransferase system
MABCCOOD_01567 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MABCCOOD_01568 1.2e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MABCCOOD_01570 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
MABCCOOD_01571 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MABCCOOD_01572 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MABCCOOD_01573 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MABCCOOD_01574 6.4e-29 2.3.1.128 K acetyltransferase
MABCCOOD_01575 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MABCCOOD_01576 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MABCCOOD_01577 1.4e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MABCCOOD_01578 2.6e-64 WQ51_03320 S cog cog4835
MABCCOOD_01579 6.4e-61 XK27_08360 S EDD domain protein, DegV family
MABCCOOD_01580 5.5e-75 XK27_08360 S EDD domain protein, DegV family
MABCCOOD_01581 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MABCCOOD_01582 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MABCCOOD_01583 0.0 yfmR S abc transporter atp-binding protein
MABCCOOD_01584 3.3e-25 U response to pH
MABCCOOD_01585 6e-140 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
MABCCOOD_01586 1.1e-164 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
MABCCOOD_01587 6.9e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MABCCOOD_01588 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MABCCOOD_01589 1.9e-77 K DNA-binding transcription factor activity
MABCCOOD_01590 0.0 lmrA1 V abc transporter atp-binding protein
MABCCOOD_01591 0.0 lmrA2 V abc transporter atp-binding protein
MABCCOOD_01592 5.4e-45 K Acetyltransferase (GNAT) family
MABCCOOD_01593 3.2e-78 sptS 2.7.13.3 T Histidine kinase
MABCCOOD_01594 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MABCCOOD_01595 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MABCCOOD_01596 5.3e-161 cvfB S Protein conserved in bacteria
MABCCOOD_01597 7.4e-35 yozE S Belongs to the UPF0346 family
MABCCOOD_01598 1.5e-123 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
MABCCOOD_01599 2.3e-61 rlpA M LysM domain protein
MABCCOOD_01600 8e-191 phoH T phosphate starvation-inducible protein PhoH
MABCCOOD_01604 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MABCCOOD_01605 1.8e-164 K transcriptional regulator (lysR family)
MABCCOOD_01606 1.4e-186 coiA 3.6.4.12 S Competence protein
MABCCOOD_01607 0.0 pepF E oligoendopeptidase F
MABCCOOD_01608 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
MABCCOOD_01609 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
MABCCOOD_01610 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MABCCOOD_01611 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MABCCOOD_01612 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MABCCOOD_01613 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
MABCCOOD_01614 2.1e-67 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MABCCOOD_01615 3.1e-53 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MABCCOOD_01616 1.8e-223 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
MABCCOOD_01617 4.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MABCCOOD_01618 2.6e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MABCCOOD_01619 1.2e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MABCCOOD_01620 5.3e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MABCCOOD_01621 2.5e-129 yxkH G deacetylase
MABCCOOD_01622 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MABCCOOD_01623 4.2e-150 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MABCCOOD_01624 1e-151 rarD S Transporter
MABCCOOD_01625 2.6e-16 T peptidase
MABCCOOD_01626 8.9e-14 coiA 3.6.4.12 S Competence protein
MABCCOOD_01627 1.5e-106 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MABCCOOD_01628 5.3e-74 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MABCCOOD_01629 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MABCCOOD_01630 1.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MABCCOOD_01631 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
MABCCOOD_01632 2.3e-76 atpF C ATP synthase F(0) sector subunit b
MABCCOOD_01633 3.5e-86 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MABCCOOD_01634 7.2e-278 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MABCCOOD_01635 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MABCCOOD_01636 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MABCCOOD_01637 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MABCCOOD_01638 2.8e-230 ftsW D Belongs to the SEDS family
MABCCOOD_01639 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MABCCOOD_01640 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MABCCOOD_01641 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MABCCOOD_01642 5.4e-161 holB 2.7.7.7 L dna polymerase iii
MABCCOOD_01643 3.1e-134 yaaT S stage 0 sporulation protein
MABCCOOD_01644 9.5e-55 yabA L Involved in initiation control of chromosome replication
MABCCOOD_01645 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MABCCOOD_01646 7.5e-233 amt P Ammonium Transporter
MABCCOOD_01647 1.1e-53 glnB K Belongs to the P(II) protein family
MABCCOOD_01648 4.9e-106 mur1 NU mannosyl-glycoprotein
MABCCOOD_01649 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
MABCCOOD_01650 1.2e-92 nptA P COG1283 Na phosphate symporter
MABCCOOD_01651 8e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MABCCOOD_01652 4.9e-51
MABCCOOD_01653 2.2e-25
MABCCOOD_01654 3.9e-60
MABCCOOD_01655 6.1e-63 S membrane
MABCCOOD_01656 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MABCCOOD_01657 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MABCCOOD_01658 4.5e-39 ynzC S UPF0291 protein
MABCCOOD_01659 1.8e-254 cycA E permease
MABCCOOD_01660 7e-09 uvrX 2.7.7.7 L impB/mucB/samB family
MABCCOOD_01661 1.7e-70 pts33BCA G pts system
MABCCOOD_01662 2.5e-119 pts33BCA G pts system
MABCCOOD_01663 1.5e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
MABCCOOD_01664 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MABCCOOD_01669 1.4e-167 fhuR K transcriptional regulator (lysR family)
MABCCOOD_01670 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MABCCOOD_01671 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MABCCOOD_01672 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MABCCOOD_01673 4.9e-227 pyrP F uracil Permease
MABCCOOD_01674 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MABCCOOD_01675 4.2e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
MABCCOOD_01676 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
MABCCOOD_01677 6.6e-131 2.1.1.223 S Putative SAM-dependent methyltransferase
MABCCOOD_01678 9.9e-36 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MABCCOOD_01679 1.2e-50 V efflux transmembrane transporter activity
MABCCOOD_01680 3.6e-32 V efflux transmembrane transporter activity
MABCCOOD_01681 7e-27 ytrF V efflux transmembrane transporter activity
MABCCOOD_01682 1.3e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MABCCOOD_01683 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MABCCOOD_01684 9.1e-110 L Transposase
MABCCOOD_01685 3.5e-110 L Transposase
MABCCOOD_01686 1.6e-18 L Integrase core domain
MABCCOOD_01687 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
MABCCOOD_01688 1.9e-96 hrtB V MacB-like periplasmic core domain
MABCCOOD_01691 3e-92 S MucBP domain
MABCCOOD_01692 1.9e-49 M YSIRK type signal peptide
MABCCOOD_01693 1.7e-142 M the current gene model (or a revised gene model) may contain a
MABCCOOD_01695 0.0 mdlB V abc transporter atp-binding protein
MABCCOOD_01696 0.0 lmrA V abc transporter atp-binding protein
MABCCOOD_01697 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MABCCOOD_01698 6.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MABCCOOD_01699 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
MABCCOOD_01700 2.5e-132 rr02 KT response regulator
MABCCOOD_01701 5.7e-219 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MABCCOOD_01702 2.8e-168 V ABC transporter
MABCCOOD_01703 5.4e-122 sagI S ABC-2 type transporter
MABCCOOD_01704 6.9e-197 yceA S Belongs to the UPF0176 family
MABCCOOD_01705 8e-28 XK27_00085 K Transcriptional
MABCCOOD_01706 1.9e-22
MABCCOOD_01707 1.1e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
MABCCOOD_01708 2.5e-113 S VIT family
MABCCOOD_01709 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MABCCOOD_01710 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MABCCOOD_01711 2.6e-17 ald 1.4.1.1 E alanine dehydrogenase activity
MABCCOOD_01712 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MABCCOOD_01713 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MABCCOOD_01714 4.6e-105 GBS0088 J protein conserved in bacteria
MABCCOOD_01715 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MABCCOOD_01716 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MABCCOOD_01717 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
MABCCOOD_01718 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MABCCOOD_01719 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MABCCOOD_01720 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
MABCCOOD_01721 2.5e-21
MABCCOOD_01722 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MABCCOOD_01724 3.5e-07 U protein secretion
MABCCOOD_01725 2.1e-50 U protein secretion
MABCCOOD_01727 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
MABCCOOD_01728 1.5e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MABCCOOD_01729 4.9e-21 XK27_13030
MABCCOOD_01730 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MABCCOOD_01731 4.9e-168 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MABCCOOD_01732 2.8e-165 S Protein of unknown function (DUF3114)
MABCCOOD_01733 1.2e-22 S Protein of unknown function (DUF3114)
MABCCOOD_01734 1.5e-118 yqfA K protein, Hemolysin III
MABCCOOD_01735 1e-25 K hmm pf08876
MABCCOOD_01736 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MABCCOOD_01737 1.7e-218 mvaS 2.3.3.10 I synthase
MABCCOOD_01738 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MABCCOOD_01739 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MABCCOOD_01740 9.7e-22
MABCCOOD_01741 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MABCCOOD_01742 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
MABCCOOD_01743 1.5e-250 mmuP E amino acid
MABCCOOD_01744 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
MABCCOOD_01745 1.4e-29 S Domain of unknown function (DUF1912)
MABCCOOD_01746 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
MABCCOOD_01747 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MABCCOOD_01748 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MABCCOOD_01749 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MABCCOOD_01750 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
MABCCOOD_01751 4.8e-16 S Protein of unknown function (DUF2969)
MABCCOOD_01754 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
MABCCOOD_01757 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
MABCCOOD_01758 6.1e-70 M Pfam SNARE associated Golgi protein
MABCCOOD_01759 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
MABCCOOD_01760 9.3e-59 S oxidoreductase
MABCCOOD_01761 9.7e-66 S oxidoreductase
MABCCOOD_01762 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
MABCCOOD_01763 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MABCCOOD_01764 0.0 clpE O Belongs to the ClpA ClpB family
MABCCOOD_01765 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MABCCOOD_01766 1.3e-34 ykuJ S protein conserved in bacteria
MABCCOOD_01767 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
MABCCOOD_01768 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
MABCCOOD_01769 1.1e-78 feoA P FeoA domain protein
MABCCOOD_01770 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MABCCOOD_01771 1.5e-07
MABCCOOD_01772 2.5e-33 yugF I carboxylic ester hydrolase activity
MABCCOOD_01773 7.5e-23 I Alpha/beta hydrolase family
MABCCOOD_01774 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MABCCOOD_01775 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MABCCOOD_01776 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
MABCCOOD_01777 8.4e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MABCCOOD_01778 2.9e-44 licT K transcriptional antiterminator
MABCCOOD_01779 6.8e-53 licT K transcriptional antiterminator
MABCCOOD_01780 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MABCCOOD_01781 8.3e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MABCCOOD_01782 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MABCCOOD_01783 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MABCCOOD_01784 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MABCCOOD_01785 2.5e-220 mdtG EGP Major facilitator Superfamily
MABCCOOD_01786 2e-33 secG U Preprotein translocase subunit SecG
MABCCOOD_01787 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MABCCOOD_01788 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MABCCOOD_01789 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MABCCOOD_01790 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
MABCCOOD_01791 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
MABCCOOD_01792 4.4e-183 ccpA K Catabolite control protein A
MABCCOOD_01793 2.8e-28 yyaQ S YjbR
MABCCOOD_01794 6.6e-101 yyaQ V Protein conserved in bacteria
MABCCOOD_01795 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MABCCOOD_01796 1e-78 yueI S Protein of unknown function (DUF1694)
MABCCOOD_01797 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MABCCOOD_01798 2e-25 WQ51_00785
MABCCOOD_01799 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MABCCOOD_01800 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
MABCCOOD_01801 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MABCCOOD_01802 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MABCCOOD_01803 2.9e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MABCCOOD_01804 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MABCCOOD_01805 1.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MABCCOOD_01806 3.2e-53 yheA S Belongs to the UPF0342 family
MABCCOOD_01807 6.7e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MABCCOOD_01808 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MABCCOOD_01809 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MABCCOOD_01810 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
MABCCOOD_01811 3.5e-250 msrR K Transcriptional regulator
MABCCOOD_01812 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
MABCCOOD_01813 9.1e-203 I acyl-CoA dehydrogenase
MABCCOOD_01814 4.5e-97 mip S hydroperoxide reductase activity
MABCCOOD_01815 5.3e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MABCCOOD_01816 8.9e-20
MABCCOOD_01817 3.2e-46
MABCCOOD_01818 1e-31 K Cro/C1-type HTH DNA-binding domain
MABCCOOD_01819 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MABCCOOD_01820 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
MABCCOOD_01821 8.1e-95
MABCCOOD_01822 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MABCCOOD_01823 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MABCCOOD_01824 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MABCCOOD_01825 1e-185 S CRISPR-associated protein Csn2 subfamily St
MABCCOOD_01826 2.7e-146 ycgQ S TIGR03943 family
MABCCOOD_01827 1.2e-155 XK27_03015 S permease
MABCCOOD_01829 0.0 yhgF K Transcriptional accessory protein
MABCCOOD_01830 9.9e-42 pspC KT PspC domain
MABCCOOD_01831 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MABCCOOD_01832 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MABCCOOD_01834 5.5e-69 ytxH S General stress protein
MABCCOOD_01836 2e-177 yegQ O Peptidase U32
MABCCOOD_01837 3.4e-252 yegQ O Peptidase U32
MABCCOOD_01838 8.1e-46 S CHY zinc finger
MABCCOOD_01839 8.4e-88 bioY S biotin synthase
MABCCOOD_01841 1.1e-33 XK27_12190 S protein conserved in bacteria
MABCCOOD_01842 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
MABCCOOD_01843 1.1e-12
MABCCOOD_01844 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
MABCCOOD_01845 0.0 L helicase
MABCCOOD_01846 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MABCCOOD_01847 1e-163 M LysM domain
MABCCOOD_01848 7.6e-16
MABCCOOD_01849 2.3e-175 S hydrolase
MABCCOOD_01850 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
MABCCOOD_01851 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MABCCOOD_01852 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
MABCCOOD_01853 2.7e-27 P Hemerythrin HHE cation binding domain protein
MABCCOOD_01854 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MABCCOOD_01855 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
MABCCOOD_01856 7.9e-37 MA20_36090 S Protein of unknown function (DUF2974)
MABCCOOD_01857 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
MABCCOOD_01858 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
MABCCOOD_01859 7.4e-114 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MABCCOOD_01861 7.9e-39
MABCCOOD_01862 6e-172 spd F DNA RNA non-specific endonuclease
MABCCOOD_01863 1.5e-92 lemA S LemA family
MABCCOOD_01864 9.3e-132 htpX O Belongs to the peptidase M48B family
MABCCOOD_01865 2.1e-74 S Psort location CytoplasmicMembrane, score
MABCCOOD_01866 5.3e-55 S Domain of unknown function (DUF4430)
MABCCOOD_01867 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MABCCOOD_01868 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
MABCCOOD_01869 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
MABCCOOD_01870 1.9e-23 L Transposase
MABCCOOD_01871 2.2e-185 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
MABCCOOD_01872 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MABCCOOD_01873 3.5e-91 dps P Belongs to the Dps family
MABCCOOD_01874 1.1e-80 perR P Belongs to the Fur family
MABCCOOD_01875 8.4e-28 yqgQ S protein conserved in bacteria
MABCCOOD_01876 2.2e-179 glk 2.7.1.2 G Glucokinase
MABCCOOD_01877 0.0 typA T GTP-binding protein TypA
MABCCOOD_01879 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MABCCOOD_01880 3.9e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MABCCOOD_01881 6.7e-172 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MABCCOOD_01882 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MABCCOOD_01883 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MABCCOOD_01884 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MABCCOOD_01885 6.8e-96 sepF D cell septum assembly
MABCCOOD_01886 2.6e-34 yggT D integral membrane protein
MABCCOOD_01887 1.2e-143 ylmH T S4 RNA-binding domain
MABCCOOD_01888 1.8e-135 divIVA D Cell division protein DivIVA
MABCCOOD_01889 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MABCCOOD_01890 8.4e-10
MABCCOOD_01891 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
MABCCOOD_01892 2e-45 rpmE2 J 50S ribosomal protein L31
MABCCOOD_01893 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MABCCOOD_01894 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
MABCCOOD_01895 2.4e-155 gst O Glutathione S-transferase
MABCCOOD_01896 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MABCCOOD_01897 2.4e-112 tdk 2.7.1.21 F thymidine kinase
MABCCOOD_01898 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MABCCOOD_01899 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MABCCOOD_01900 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MABCCOOD_01901 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MABCCOOD_01902 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
MABCCOOD_01903 6.6e-105 pvaA M lytic transglycosylase activity
MABCCOOD_01904 0.0 yfiB1 V abc transporter atp-binding protein
MABCCOOD_01905 0.0 XK27_10035 V abc transporter atp-binding protein
MABCCOOD_01906 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
MABCCOOD_01907 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MABCCOOD_01908 3.9e-237 dltB M Membrane protein involved in D-alanine export
MABCCOOD_01909 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MABCCOOD_01910 1.4e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MABCCOOD_01911 3.1e-234 L Transposase
MABCCOOD_01912 9.1e-83 L Integrase core domain protein
MABCCOOD_01913 7.2e-53 L transposition
MABCCOOD_01914 7.7e-19 L transposase activity
MABCCOOD_01915 0.0 3.6.3.8 P cation transport ATPase
MABCCOOD_01916 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
MABCCOOD_01918 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MABCCOOD_01919 7.3e-166 metF 1.5.1.20 E reductase
MABCCOOD_01920 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MABCCOOD_01921 1.7e-94 panT S ECF transporter, substrate-specific component
MABCCOOD_01922 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MABCCOOD_01923 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
MABCCOOD_01924 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MABCCOOD_01925 1.4e-90 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MABCCOOD_01926 2.8e-40 T PhoQ Sensor
MABCCOOD_01927 1.3e-128 T PhoQ Sensor

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)