ORF_ID e_value Gene_name EC_number CAZy COGs Description
IICANBEH_00006 1.3e-140 mreC M Involved in formation and maintenance of cell shape
IICANBEH_00007 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IICANBEH_00008 2e-96 usp 3.5.1.28 CBM50 S CHAP domain
IICANBEH_00009 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IICANBEH_00010 2.5e-26
IICANBEH_00011 5.9e-219 araT 2.6.1.1 E Aminotransferase
IICANBEH_00012 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
IICANBEH_00013 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IICANBEH_00014 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IICANBEH_00015 5.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IICANBEH_00016 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IICANBEH_00017 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IICANBEH_00018 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IICANBEH_00019 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IICANBEH_00020 1.9e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IICANBEH_00021 1e-90 L transposase activity
IICANBEH_00022 3.5e-50 L transposition
IICANBEH_00023 2e-32 L Integrase core domain protein
IICANBEH_00024 2.3e-161 S CHAP domain
IICANBEH_00025 1e-240 purD 6.3.4.13 F Belongs to the GARS family
IICANBEH_00026 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IICANBEH_00027 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IICANBEH_00028 7e-141 1.1.1.169 H Ketopantoate reductase
IICANBEH_00029 1e-23
IICANBEH_00030 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IICANBEH_00031 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IICANBEH_00032 2e-211 sip L Belongs to the 'phage' integrase family
IICANBEH_00033 4.5e-15 K Cro/C1-type HTH DNA-binding domain
IICANBEH_00034 1.2e-20 K TRANSCRIPTIONal
IICANBEH_00038 1.2e-14
IICANBEH_00039 3.1e-22
IICANBEH_00040 1e-143 KL Phage plasmid primase P4 family
IICANBEH_00041 2e-296 S DNA primase
IICANBEH_00043 2.3e-12
IICANBEH_00046 1.5e-52
IICANBEH_00047 8.2e-70 argR K Regulates arginine biosynthesis genes
IICANBEH_00048 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IICANBEH_00049 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IICANBEH_00050 2.3e-78 S Protein of unknown function (DUF3021)
IICANBEH_00051 5.4e-69 K LytTr DNA-binding domain
IICANBEH_00053 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IICANBEH_00055 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IICANBEH_00056 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
IICANBEH_00057 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
IICANBEH_00058 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IICANBEH_00059 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
IICANBEH_00060 2.6e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
IICANBEH_00061 1.3e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IICANBEH_00062 3.2e-92 dps P Belongs to the Dps family
IICANBEH_00063 1.1e-80 perR P Belongs to the Fur family
IICANBEH_00064 8.4e-28 yqgQ S protein conserved in bacteria
IICANBEH_00065 2.2e-179 glk 2.7.1.2 G Glucokinase
IICANBEH_00066 0.0 typA T GTP-binding protein TypA
IICANBEH_00068 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IICANBEH_00069 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IICANBEH_00070 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IICANBEH_00071 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IICANBEH_00072 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IICANBEH_00073 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IICANBEH_00074 1.4e-96 sepF D cell septum assembly
IICANBEH_00075 2e-34 yggT D integral membrane protein
IICANBEH_00076 6.1e-143 ylmH T S4 RNA-binding domain
IICANBEH_00077 1.8e-135 divIVA D Cell division protein DivIVA
IICANBEH_00078 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IICANBEH_00079 8.4e-10
IICANBEH_00080 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
IICANBEH_00081 2e-45 rpmE2 J 50S ribosomal protein L31
IICANBEH_00082 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IICANBEH_00083 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
IICANBEH_00084 8.9e-155 gst O Glutathione S-transferase
IICANBEH_00085 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IICANBEH_00086 2.4e-112 tdk 2.7.1.21 F thymidine kinase
IICANBEH_00087 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IICANBEH_00088 1.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IICANBEH_00089 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IICANBEH_00090 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IICANBEH_00091 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
IICANBEH_00092 8e-100 pvaA M lytic transglycosylase activity
IICANBEH_00093 0.0 yfiB1 V abc transporter atp-binding protein
IICANBEH_00094 0.0 XK27_10035 V abc transporter atp-binding protein
IICANBEH_00095 1.5e-09 S D-Ala-teichoic acid biosynthesis protein
IICANBEH_00096 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICANBEH_00097 3.9e-237 dltB M Membrane protein involved in D-alanine export
IICANBEH_00098 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICANBEH_00099 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IICANBEH_00100 6.3e-34 L Integrase core domain protein
IICANBEH_00101 9.6e-32 L transposition
IICANBEH_00102 6.5e-54 L transposition
IICANBEH_00103 7.7e-19 L transposase activity
IICANBEH_00104 0.0 3.6.3.8 P cation transport ATPase
IICANBEH_00105 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
IICANBEH_00107 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IICANBEH_00108 7.3e-166 metF 1.5.1.20 E reductase
IICANBEH_00109 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IICANBEH_00110 1.7e-94 panT S ECF transporter, substrate-specific component
IICANBEH_00111 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IICANBEH_00112 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
IICANBEH_00113 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IICANBEH_00114 7.5e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICANBEH_00115 1e-29 T PhoQ Sensor
IICANBEH_00116 1.1e-13 L Transposase
IICANBEH_00117 2.1e-30 rpsT J rRNA binding
IICANBEH_00118 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
IICANBEH_00119 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
IICANBEH_00120 1.9e-25 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IICANBEH_00121 3e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IICANBEH_00122 7.1e-99 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IICANBEH_00123 2.7e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IICANBEH_00124 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IICANBEH_00125 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IICANBEH_00126 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IICANBEH_00127 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IICANBEH_00128 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
IICANBEH_00129 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
IICANBEH_00130 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IICANBEH_00131 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IICANBEH_00132 3.1e-81 ypmB S Protein conserved in bacteria
IICANBEH_00133 4.7e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IICANBEH_00134 4.9e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IICANBEH_00135 1.5e-07
IICANBEH_00136 2.4e-30
IICANBEH_00137 3e-13
IICANBEH_00138 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
IICANBEH_00139 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IICANBEH_00140 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
IICANBEH_00141 3e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IICANBEH_00142 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IICANBEH_00143 2.2e-19 D nuclear chromosome segregation
IICANBEH_00144 2.8e-137 yejC S cyclic nucleotide-binding protein
IICANBEH_00145 1.2e-163 rapZ S Displays ATPase and GTPase activities
IICANBEH_00146 4.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IICANBEH_00147 8.7e-162 whiA K May be required for sporulation
IICANBEH_00148 8.2e-120 pepD E Dipeptidase
IICANBEH_00149 2.6e-44 pepD E Dipeptidase
IICANBEH_00150 1.5e-75 tspO T TspO/MBR family
IICANBEH_00151 1.9e-59 S Uncharacterised lipoprotein family
IICANBEH_00152 1e-223 L Transposase
IICANBEH_00153 4.9e-63 tnp L DDE domain
IICANBEH_00154 7.1e-28 L transposase activity
IICANBEH_00156 1.7e-25
IICANBEH_00157 5.4e-32 cspD K Cold shock protein domain
IICANBEH_00158 9.4e-43 K Cold-Shock Protein
IICANBEH_00159 0.0 copB 3.6.3.4 P haloacid dehalogenase-like hydrolase
IICANBEH_00160 8.4e-190 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IICANBEH_00161 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IICANBEH_00162 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IICANBEH_00163 1.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IICANBEH_00164 3.9e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
IICANBEH_00165 4.9e-111 hsdM 2.1.1.72 V type I restriction-modification system
IICANBEH_00166 1.6e-29 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IICANBEH_00167 4.5e-155 glcU U Glucose uptake
IICANBEH_00168 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
IICANBEH_00169 1.2e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
IICANBEH_00170 1.3e-88 XK27_10720 D peptidase activity
IICANBEH_00171 1.4e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
IICANBEH_00172 2.2e-08
IICANBEH_00173 2.7e-172 yeiH S Membrane
IICANBEH_00174 2.4e-114 mur1 NU muramidase
IICANBEH_00175 2.4e-83 L transposition
IICANBEH_00176 4.5e-166 cpsY K Transcriptional regulator
IICANBEH_00177 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IICANBEH_00178 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
IICANBEH_00179 5.3e-105 artQ P ABC transporter (Permease
IICANBEH_00180 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
IICANBEH_00181 1.2e-157 aatB ET ABC transporter substrate-binding protein
IICANBEH_00182 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IICANBEH_00183 2.1e-07
IICANBEH_00184 1.6e-58 adhP 1.1.1.1 C alcohol dehydrogenase
IICANBEH_00185 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
IICANBEH_00186 8.3e-49 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
IICANBEH_00187 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IICANBEH_00188 2e-126 gntR1 K transcriptional
IICANBEH_00189 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IICANBEH_00190 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IICANBEH_00191 4.1e-87 niaX
IICANBEH_00192 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
IICANBEH_00193 1.8e-127 K DNA-binding helix-turn-helix protein
IICANBEH_00194 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IICANBEH_00195 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IICANBEH_00196 4.1e-167 GK ROK family
IICANBEH_00197 9.2e-158 dprA LU DNA protecting protein DprA
IICANBEH_00198 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IICANBEH_00199 3.6e-154 S TraX protein
IICANBEH_00200 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICANBEH_00201 2.8e-252 T PhoQ Sensor
IICANBEH_00202 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IICANBEH_00203 1.4e-152 XK27_05470 E Methionine synthase
IICANBEH_00204 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IICANBEH_00205 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IICANBEH_00206 1.8e-51 IQ Acetoin reductase
IICANBEH_00207 3.9e-19 IQ Acetoin reductase
IICANBEH_00208 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IICANBEH_00209 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IICANBEH_00212 1.1e-212 pqqE C radical SAM domain protein
IICANBEH_00213 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
IICANBEH_00214 6.6e-61 EGP Major facilitator Superfamily
IICANBEH_00215 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IICANBEH_00216 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IICANBEH_00217 7e-110 L Transposase
IICANBEH_00218 6.4e-104 V ABC transporter (Permease
IICANBEH_00219 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IICANBEH_00220 1.6e-10
IICANBEH_00221 1.2e-97 K Transcriptional regulator, TetR family
IICANBEH_00222 1.8e-159 czcD P cation diffusion facilitator family transporter
IICANBEH_00223 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IICANBEH_00224 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
IICANBEH_00225 6e-08 S Hydrolases of the alpha beta superfamily
IICANBEH_00226 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
IICANBEH_00227 5.9e-79 S Alpha/beta hydrolase of unknown function (DUF915)
IICANBEH_00230 1.2e-143 2.4.2.3 F Phosphorylase superfamily
IICANBEH_00231 9.2e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
IICANBEH_00232 5.1e-33 yclQ P ABC-type enterochelin transport system, periplasmic component
IICANBEH_00233 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
IICANBEH_00234 8.6e-15 dinF V Mate efflux family protein
IICANBEH_00236 3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IICANBEH_00237 7.1e-209 sip L Belongs to the 'phage' integrase family
IICANBEH_00238 5.2e-144 V COG4823 Abortive infection bacteriophage resistance protein
IICANBEH_00239 8.3e-18 K Transcriptional
IICANBEH_00240 9.5e-21 K Cro/C1-type HTH DNA-binding domain
IICANBEH_00241 2.3e-100 S Phage regulatory protein Rha (Phage_pRha)
IICANBEH_00245 9e-22
IICANBEH_00246 5.7e-131 KL Phage plasmid primase P4 family
IICANBEH_00247 1.2e-66 S Virulence-associated protein E
IICANBEH_00248 5.8e-127 S Protein conserved in bacteria
IICANBEH_00251 1.5e-196 dcm 2.1.1.37 H cytosine-specific methyltransferase
IICANBEH_00252 1.2e-167 S NgoFVII restriction endonuclease
IICANBEH_00254 2e-30
IICANBEH_00256 1.5e-46 S TraX protein
IICANBEH_00257 8.3e-59 S TraX protein
IICANBEH_00258 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
IICANBEH_00259 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IICANBEH_00260 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IICANBEH_00261 1.5e-183 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IICANBEH_00262 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IICANBEH_00263 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
IICANBEH_00264 0.0 csm1 S CRISPR-associated protein Csm1 family
IICANBEH_00265 2.5e-62 csm2 L Csm2 Type III-A
IICANBEH_00266 1.6e-117 csm3 L RAMP superfamily
IICANBEH_00267 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
IICANBEH_00268 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
IICANBEH_00270 9.5e-32 csm6 S Psort location Cytoplasmic, score
IICANBEH_00271 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IICANBEH_00272 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IICANBEH_00273 1.6e-266 dtpT E transporter
IICANBEH_00274 4e-62 yecS P ABC transporter (Permease
IICANBEH_00275 2.3e-20 yecS P amino acid transport
IICANBEH_00277 2e-272 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IICANBEH_00278 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
IICANBEH_00279 1.4e-104 yfiF3 K sequence-specific DNA binding
IICANBEH_00280 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IICANBEH_00281 1.8e-240 agcS E (Alanine) symporter
IICANBEH_00282 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IICANBEH_00283 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
IICANBEH_00284 1.8e-31 S haloacid dehalogenase-like hydrolase
IICANBEH_00285 7.8e-61 S haloacid dehalogenase-like hydrolase
IICANBEH_00286 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IICANBEH_00287 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
IICANBEH_00288 6.3e-32 M1-755 P Hemerythrin HHE cation binding domain protein
IICANBEH_00289 5.4e-95 XK27_04775 S hemerythrin HHE cation binding domain
IICANBEH_00290 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
IICANBEH_00291 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IICANBEH_00292 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IICANBEH_00293 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IICANBEH_00294 1.9e-43 yktA S Belongs to the UPF0223 family
IICANBEH_00295 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IICANBEH_00296 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IICANBEH_00297 3.3e-158 pstS P phosphate
IICANBEH_00298 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
IICANBEH_00299 1.2e-155 pstA P phosphate transport system permease
IICANBEH_00300 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IICANBEH_00301 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IICANBEH_00302 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
IICANBEH_00303 0.0 pepN 3.4.11.2 E aminopeptidase
IICANBEH_00304 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IICANBEH_00305 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
IICANBEH_00306 3e-08
IICANBEH_00307 3.6e-09
IICANBEH_00308 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IICANBEH_00309 1.1e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
IICANBEH_00310 1.3e-48 malR K Transcriptional regulator
IICANBEH_00311 2.3e-23 L Transposase
IICANBEH_00312 4.6e-25 tatA U protein secretion
IICANBEH_00313 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IICANBEH_00314 7.4e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
IICANBEH_00315 5.6e-233 ycdB P peroxidase
IICANBEH_00316 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
IICANBEH_00317 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IICANBEH_00318 1.8e-84 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IICANBEH_00319 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IICANBEH_00320 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IICANBEH_00321 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IICANBEH_00322 1.9e-37 3.5.1.28 NU amidase activity
IICANBEH_00323 6.8e-131 3.5.1.28 M GBS Bsp-like repeat
IICANBEH_00324 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IICANBEH_00325 9.9e-12 3.5.1.28 NU amidase activity
IICANBEH_00326 0.0 lpdA 1.8.1.4 C Dehydrogenase
IICANBEH_00327 1e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IICANBEH_00328 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IICANBEH_00329 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IICANBEH_00330 3.6e-46 hpk9 2.7.13.3 T protein histidine kinase activity
IICANBEH_00331 3.5e-241 cas3 L CRISPR-associated helicase, Cas3
IICANBEH_00332 0.0 S the current gene model (or a revised gene model) may contain a frame shift
IICANBEH_00333 9.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IICANBEH_00334 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IICANBEH_00335 4.3e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IICANBEH_00336 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
IICANBEH_00337 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
IICANBEH_00338 4.1e-127 3.4.16.4 M Belongs to the peptidase S11 family
IICANBEH_00339 1.2e-157 rssA S Phospholipase, patatin family
IICANBEH_00340 1.8e-69 estA E GDSL-like protein
IICANBEH_00341 3.4e-29 estA E Lysophospholipase L1 and related esterases
IICANBEH_00342 3.5e-291 S unusual protein kinase
IICANBEH_00343 4.9e-39 S granule-associated protein
IICANBEH_00344 2.6e-107 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IICANBEH_00345 8.4e-27 bglH 3.2.1.86 GT1 G beta-glucosidase activity
IICANBEH_00346 1e-196 S hmm pf01594
IICANBEH_00347 3.9e-102 G Belongs to the phosphoglycerate mutase family
IICANBEH_00348 5.8e-81 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IICANBEH_00349 2.2e-94 V VanZ like family
IICANBEH_00350 7.7e-103 L Transposase
IICANBEH_00351 1.1e-110 L Transposase
IICANBEH_00352 1.4e-192 wbbI M transferase activity, transferring glycosyl groups
IICANBEH_00353 2e-213 glf 5.4.99.9 M UDP-galactopyranose mutase
IICANBEH_00354 3.5e-242 epsU S Polysaccharide biosynthesis protein
IICANBEH_00355 6.3e-173
IICANBEH_00356 4.4e-159 M Glycosyltransferase like family 2
IICANBEH_00357 8.3e-126 M Glycosyltransferase, group 2 family protein
IICANBEH_00358 6.8e-113 Z012_10770 M Domain of unknown function (DUF1919)
IICANBEH_00359 3.5e-208 wcoF M Glycosyltransferase, group 1 family protein
IICANBEH_00360 2.2e-218 rgpAc GT4 M group 1 family protein
IICANBEH_00361 2.6e-250 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IICANBEH_00362 7.2e-114 cpsD D COG0489 ATPases involved in chromosome partitioning
IICANBEH_00363 2.7e-107 cps4C M biosynthesis protein
IICANBEH_00364 2.3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
IICANBEH_00365 1.5e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
IICANBEH_00366 9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
IICANBEH_00367 1.5e-119 yfeJ 6.3.5.2 F glutamine amidotransferase
IICANBEH_00368 1.6e-40 clcA_2 P chloride
IICANBEH_00369 3.8e-42 clcA_2 P chloride channel
IICANBEH_00370 5.8e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IICANBEH_00371 1.3e-41 S Protein of unknown function (DUF1697)
IICANBEH_00372 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IICANBEH_00373 5e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IICANBEH_00374 1e-21 V Glucan-binding protein C
IICANBEH_00375 4.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
IICANBEH_00376 2.4e-275 pepV 3.5.1.18 E Dipeptidase
IICANBEH_00377 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IICANBEH_00378 3.8e-60 XK27_03610 K Gnat family
IICANBEH_00379 2.2e-84 L Transposase
IICANBEH_00380 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IICANBEH_00381 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IICANBEH_00382 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IICANBEH_00383 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IICANBEH_00384 3.9e-15 M LysM domain
IICANBEH_00385 2.9e-90 ebsA S Family of unknown function (DUF5322)
IICANBEH_00386 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IICANBEH_00387 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IICANBEH_00388 3.7e-224 G COG0457 FOG TPR repeat
IICANBEH_00389 3.1e-175 yubA S permease
IICANBEH_00390 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
IICANBEH_00391 1.1e-162 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IICANBEH_00392 2.5e-124 ftsE D cell division ATP-binding protein FtsE
IICANBEH_00393 1.3e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IICANBEH_00394 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IICANBEH_00395 1.3e-181 yjjH S Calcineurin-like phosphoesterase
IICANBEH_00396 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IICANBEH_00397 0.0 pacL 3.6.3.8 P cation transport ATPase
IICANBEH_00398 2.6e-67 ywiB S Domain of unknown function (DUF1934)
IICANBEH_00399 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
IICANBEH_00400 9.2e-147 yidA S hydrolases of the HAD superfamily
IICANBEH_00401 5.3e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
IICANBEH_00402 5e-35 F Protein of unknown function (DUF454)
IICANBEH_00403 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
IICANBEH_00404 1.9e-234 vicK 2.7.13.3 T Histidine kinase
IICANBEH_00405 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICANBEH_00406 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
IICANBEH_00407 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IICANBEH_00408 4.7e-115 gltJ P ABC transporter (Permease
IICANBEH_00409 4.2e-110 tcyB_2 P ABC transporter (permease)
IICANBEH_00410 2.4e-124 endA F DNA RNA non-specific endonuclease
IICANBEH_00411 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
IICANBEH_00412 7.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IICANBEH_00414 1.9e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IICANBEH_00415 6.4e-20 G Domain of unknown function (DUF4832)
IICANBEH_00417 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IICANBEH_00418 1.7e-173 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IICANBEH_00419 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IICANBEH_00420 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
IICANBEH_00421 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IICANBEH_00422 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
IICANBEH_00425 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IICANBEH_00426 3.2e-220 XK27_05110 P chloride
IICANBEH_00427 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
IICANBEH_00428 7e-281 clcA P Chloride transporter, ClC family
IICANBEH_00429 2.3e-75 fld C Flavodoxin
IICANBEH_00431 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
IICANBEH_00432 4.6e-151 estA CE1 S Putative esterase
IICANBEH_00433 6.6e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IICANBEH_00434 1.2e-135 XK27_08845 S abc transporter atp-binding protein
IICANBEH_00435 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
IICANBEH_00436 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
IICANBEH_00437 1.6e-16 S Domain of unknown function (DUF4649)
IICANBEH_00439 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
IICANBEH_00440 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
IICANBEH_00443 9.3e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IICANBEH_00444 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IICANBEH_00445 0.0 dnaE 2.7.7.7 L DNA polymerase
IICANBEH_00446 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
IICANBEH_00447 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IICANBEH_00448 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IICANBEH_00449 2.5e-43 ysdA L Membrane
IICANBEH_00450 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IICANBEH_00451 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IICANBEH_00452 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IICANBEH_00453 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IICANBEH_00455 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IICANBEH_00456 1.7e-83 ypmS S Protein conserved in bacteria
IICANBEH_00457 6e-144 ypmR E lipolytic protein G-D-S-L family
IICANBEH_00458 1e-148 DegV S DegV family
IICANBEH_00459 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
IICANBEH_00460 3.7e-73 argR K Regulates arginine biosynthesis genes
IICANBEH_00461 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IICANBEH_00462 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IICANBEH_00463 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
IICANBEH_00464 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IICANBEH_00467 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IICANBEH_00468 3.8e-125 dnaD
IICANBEH_00469 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IICANBEH_00470 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IICANBEH_00471 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
IICANBEH_00472 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IICANBEH_00473 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IICANBEH_00474 3.9e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IICANBEH_00475 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IICANBEH_00476 5.4e-197 L transposase, IS4 family
IICANBEH_00477 5.6e-240 rodA D Belongs to the SEDS family
IICANBEH_00478 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
IICANBEH_00479 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IICANBEH_00480 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IICANBEH_00481 8.5e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IICANBEH_00482 4.7e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IICANBEH_00483 2.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IICANBEH_00484 2.6e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IICANBEH_00485 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IICANBEH_00486 1.4e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IICANBEH_00487 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IICANBEH_00489 6.6e-31 L Integrase core domain protein
IICANBEH_00490 3.6e-91 L Transposase
IICANBEH_00491 1.3e-22 XK27_08085
IICANBEH_00492 5e-71 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IICANBEH_00493 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IICANBEH_00494 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IICANBEH_00495 1.1e-121 ylfI S tigr01906
IICANBEH_00496 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IICANBEH_00497 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
IICANBEH_00498 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
IICANBEH_00501 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IICANBEH_00502 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IICANBEH_00503 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IICANBEH_00504 1.1e-206 yurR 1.4.5.1 E oxidoreductase
IICANBEH_00505 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
IICANBEH_00506 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IICANBEH_00507 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
IICANBEH_00508 1.7e-70 gtrA S GtrA-like protein
IICANBEH_00509 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IICANBEH_00510 6e-169 ybbR S Protein conserved in bacteria
IICANBEH_00511 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IICANBEH_00512 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
IICANBEH_00513 8.7e-150 cobQ S glutamine amidotransferase
IICANBEH_00514 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IICANBEH_00515 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
IICANBEH_00516 0.0 uup S abc transporter atp-binding protein
IICANBEH_00517 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IICANBEH_00518 1.9e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
IICANBEH_00519 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IICANBEH_00520 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
IICANBEH_00521 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IICANBEH_00522 7.9e-39 ptsH G phosphocarrier protein Hpr
IICANBEH_00523 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
IICANBEH_00524 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
IICANBEH_00525 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IICANBEH_00526 2.2e-34 nrdH O Glutaredoxin
IICANBEH_00527 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IICANBEH_00528 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IICANBEH_00530 1.7e-72 L Transposase (IS116 IS110 IS902 family)
IICANBEH_00531 3.6e-61 L Transposase (IS116 IS110 IS902 family)
IICANBEH_00532 2.4e-165 ypuA S secreted protein
IICANBEH_00533 8.3e-51 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
IICANBEH_00534 1.4e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
IICANBEH_00535 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IICANBEH_00536 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IICANBEH_00537 3.4e-258 noxE P NADH oxidase
IICANBEH_00538 1.9e-294 yfmM S abc transporter atp-binding protein
IICANBEH_00539 2.8e-83 XK27_01265 S ECF-type riboflavin transporter, S component
IICANBEH_00540 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IICANBEH_00541 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IICANBEH_00542 2e-86 S ECF-type riboflavin transporter, S component
IICANBEH_00544 2.9e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IICANBEH_00545 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
IICANBEH_00547 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IICANBEH_00548 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IICANBEH_00549 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IICANBEH_00550 0.0 smc D Required for chromosome condensation and partitioning
IICANBEH_00551 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IICANBEH_00552 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IICANBEH_00553 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IICANBEH_00554 2.4e-92 pat 2.3.1.183 M acetyltransferase
IICANBEH_00555 1.6e-11 L Transposase
IICANBEH_00556 3.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IICANBEH_00557 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IICANBEH_00558 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IICANBEH_00559 1.2e-62 bioY S biotin transmembrane transporter activity
IICANBEH_00560 2e-88 proW P Binding-protein-dependent transport system inner membrane component
IICANBEH_00561 1.6e-137 proV E abc transporter atp-binding protein
IICANBEH_00562 2.9e-165 proX M ABC transporter, substrate-binding protein, QAT family
IICANBEH_00563 3e-111 proWZ P ABC transporter (Permease
IICANBEH_00564 1.2e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
IICANBEH_00565 1.6e-205 S Protein of unknown function (DUF917)
IICANBEH_00566 5e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IICANBEH_00567 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
IICANBEH_00568 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IICANBEH_00569 1.5e-192 desK 2.7.13.3 T Histidine kinase
IICANBEH_00570 2.6e-132 yvfS V ABC-2 type transporter
IICANBEH_00571 8.7e-159 XK27_09825 V abc transporter atp-binding protein
IICANBEH_00575 3e-61 EGP Major facilitator Superfamily
IICANBEH_00576 1.6e-152 mutR K Transcriptional activator, Rgg GadR MutR family
IICANBEH_00577 4.6e-42 3.6.1.55 F NUDIX domain
IICANBEH_00579 3.7e-122 S An automated process has identified a potential problem with this gene model
IICANBEH_00580 1.9e-24 XK27_09825 V 'abc transporter, ATP-binding protein
IICANBEH_00581 1.4e-15 liaI KT membrane
IICANBEH_00582 2.6e-30 liaI KT membrane
IICANBEH_00583 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
IICANBEH_00584 0.0 V ABC transporter (permease)
IICANBEH_00585 1.9e-133 macB2 V ABC transporter, ATP-binding protein
IICANBEH_00586 6.2e-166 T Histidine kinase
IICANBEH_00587 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICANBEH_00588 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IICANBEH_00589 3.3e-69 pbuX F xanthine permease
IICANBEH_00590 7.8e-118 pbuX F xanthine permease
IICANBEH_00591 1.5e-247 norM V Multidrug efflux pump
IICANBEH_00592 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IICANBEH_00593 4.3e-234 brnQ E Component of the transport system for branched-chain amino acids
IICANBEH_00594 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
IICANBEH_00595 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
IICANBEH_00596 9.6e-26 csbD K CsbD-like
IICANBEH_00597 1.5e-245 yfnA E amino acid
IICANBEH_00598 2.2e-108 XK27_02070 S nitroreductase
IICANBEH_00599 9.5e-150 1.13.11.2 S glyoxalase
IICANBEH_00600 5.6e-77 ywnA K Transcriptional regulator
IICANBEH_00601 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
IICANBEH_00602 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IICANBEH_00603 1.4e-110 drgA C Nitroreductase
IICANBEH_00604 3e-102 yoaK S Protein of unknown function (DUF1275)
IICANBEH_00606 6.8e-161 yvgN C reductase
IICANBEH_00607 5.7e-180 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IICANBEH_00608 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
IICANBEH_00610 1.1e-37 BP1961 P nitric oxide dioxygenase activity
IICANBEH_00611 1.4e-54 K response regulator
IICANBEH_00612 1.3e-70 S Signal peptide protein, YSIRK family
IICANBEH_00614 3.2e-59
IICANBEH_00615 1.8e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IICANBEH_00616 1.9e-35
IICANBEH_00617 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
IICANBEH_00618 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
IICANBEH_00619 5.8e-109 MA20_06410 E LysE type translocator
IICANBEH_00620 5.6e-08
IICANBEH_00621 2.7e-09
IICANBEH_00622 0.0 M family 8
IICANBEH_00624 1.1e-151 V MatE
IICANBEH_00626 7.3e-74 C Fe-S oxidoreductases
IICANBEH_00627 1.5e-27 C Fe-S oxidoreductases
IICANBEH_00628 9.7e-176 EGP Major Facilitator Superfamily
IICANBEH_00629 1.6e-257 I radical SAM domain protein
IICANBEH_00631 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IICANBEH_00632 1.4e-150 L Integrase core domain protein
IICANBEH_00633 1.8e-87 L transposase activity
IICANBEH_00635 2.8e-85
IICANBEH_00636 0.0 sbcC L ATPase involved in DNA repair
IICANBEH_00637 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IICANBEH_00638 0.0 lacL 3.2.1.23 G -beta-galactosidase
IICANBEH_00639 0.0 lacS G transporter
IICANBEH_00640 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IICANBEH_00641 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IICANBEH_00642 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IICANBEH_00643 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IICANBEH_00644 3.4e-183 galR K Transcriptional regulator
IICANBEH_00645 2.7e-08 L Integrase core domain protein
IICANBEH_00646 1.2e-25 L transposition
IICANBEH_00647 1.6e-103 M translation initiation factor activity
IICANBEH_00648 5.7e-90 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IICANBEH_00649 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IICANBEH_00650 5.5e-101 V abc transporter atp-binding protein
IICANBEH_00651 2.5e-40 V (ABC) transporter
IICANBEH_00652 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IICANBEH_00653 2.3e-87 L Transposase
IICANBEH_00654 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IICANBEH_00655 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IICANBEH_00656 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IICANBEH_00657 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IICANBEH_00660 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IICANBEH_00661 5.8e-175 vraS 2.7.13.3 T Histidine kinase
IICANBEH_00662 3.7e-120 yvqF KT membrane
IICANBEH_00663 1.8e-307 prkC 2.7.11.1 KLT serine threonine protein kinase
IICANBEH_00664 9.9e-132 stp 3.1.3.16 T phosphatase
IICANBEH_00665 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IICANBEH_00666 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IICANBEH_00667 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IICANBEH_00668 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
IICANBEH_00669 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IICANBEH_00670 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IICANBEH_00671 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
IICANBEH_00672 2.1e-148 supH S overlaps another CDS with the same product name
IICANBEH_00673 8.6e-63 yvoA_1 K Transcriptional
IICANBEH_00674 4.9e-120 skfE V abc transporter atp-binding protein
IICANBEH_00675 6.2e-132 V ATPase activity
IICANBEH_00676 1.2e-171 oppF P Belongs to the ABC transporter superfamily
IICANBEH_00677 8.4e-204 oppD P Belongs to the ABC transporter superfamily
IICANBEH_00678 3.1e-167 amiD P ABC transporter (Permease
IICANBEH_00679 2.5e-267 amiC P ABC transporter (Permease
IICANBEH_00680 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IICANBEH_00681 1.6e-24 oppF P Belongs to the ABC transporter superfamily
IICANBEH_00682 5e-45 oppF P Belongs to the ABC transporter superfamily
IICANBEH_00683 1.4e-40 tatD L Hydrolase, tatd
IICANBEH_00684 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
IICANBEH_00685 1e-110 L Integrase core domain protein
IICANBEH_00686 3.2e-79 L Transposase
IICANBEH_00687 4.5e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IICANBEH_00688 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IICANBEH_00689 1.2e-149 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IICANBEH_00690 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
IICANBEH_00691 1.5e-103 yjbK S Adenylate cyclase
IICANBEH_00692 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IICANBEH_00693 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
IICANBEH_00694 2e-58 XK27_04120 S Putative amino acid metabolism
IICANBEH_00695 8.2e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IICANBEH_00696 1.6e-131 puuD T peptidase C26
IICANBEH_00697 5.3e-119 radC E Belongs to the UPF0758 family
IICANBEH_00698 0.0 rgpF M Rhamnan synthesis protein F
IICANBEH_00699 8.2e-196 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IICANBEH_00700 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IICANBEH_00701 2.8e-143 rgpC GM Transport permease protein
IICANBEH_00702 2.2e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
IICANBEH_00703 1.3e-226 rgpA GT4 M Domain of unknown function (DUF1972)
IICANBEH_00704 3.5e-127 tagF 2.7.8.12 M Glycosyl transferase, family 2
IICANBEH_00705 1.9e-215 amrA S polysaccharide biosynthetic process
IICANBEH_00706 1.5e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
IICANBEH_00707 1.9e-124 ycbB S Glycosyl transferase family 2
IICANBEH_00708 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IICANBEH_00709 1.1e-245
IICANBEH_00710 1.6e-171 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IICANBEH_00711 1.4e-251 M Psort location CytoplasmicMembrane, score
IICANBEH_00712 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
IICANBEH_00713 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IICANBEH_00714 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IICANBEH_00715 1.6e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IICANBEH_00716 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
IICANBEH_00717 1.4e-201 arcT 2.6.1.1 E Aminotransferase
IICANBEH_00718 2.5e-136 ET ABC transporter
IICANBEH_00719 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
IICANBEH_00720 2.9e-84 mutT 3.6.1.55 F Nudix family
IICANBEH_00721 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IICANBEH_00723 5.1e-74 S CAAX amino terminal protease family protein
IICANBEH_00724 2.4e-33 S CAAX amino terminal protease family protein
IICANBEH_00725 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
IICANBEH_00726 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IICANBEH_00727 2.4e-16 XK27_00735
IICANBEH_00728 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IICANBEH_00730 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IICANBEH_00733 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
IICANBEH_00734 3e-37 ycaO O OsmC-like protein
IICANBEH_00736 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
IICANBEH_00738 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
IICANBEH_00739 7.8e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IICANBEH_00740 5.4e-161 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IICANBEH_00741 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IICANBEH_00742 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
IICANBEH_00743 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IICANBEH_00744 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IICANBEH_00745 2.8e-108 3.1.3.18 S IA, variant 1
IICANBEH_00746 2.2e-117 lrgB M effector of murein hydrolase
IICANBEH_00747 1.7e-55 lrgA S Effector of murein hydrolase LrgA
IICANBEH_00749 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
IICANBEH_00750 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
IICANBEH_00751 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IICANBEH_00752 1.9e-103 wecD M Acetyltransferase GNAT family
IICANBEH_00753 8.8e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IICANBEH_00754 2.7e-97 GK ROK family
IICANBEH_00755 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
IICANBEH_00756 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
IICANBEH_00757 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
IICANBEH_00758 2.3e-206 potD P spermidine putrescine ABC transporter
IICANBEH_00759 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
IICANBEH_00760 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
IICANBEH_00761 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IICANBEH_00762 7.8e-171 murB 1.3.1.98 M cell wall formation
IICANBEH_00763 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IICANBEH_00764 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IICANBEH_00765 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
IICANBEH_00766 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IICANBEH_00767 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
IICANBEH_00768 0.0 ydaO E amino acid
IICANBEH_00769 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IICANBEH_00770 4.1e-37 ylqC L Belongs to the UPF0109 family
IICANBEH_00771 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IICANBEH_00772 2e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
IICANBEH_00773 2.6e-157 xth 3.1.11.2 L exodeoxyribonuclease III
IICANBEH_00774 2.1e-74 S QueT transporter
IICANBEH_00775 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
IICANBEH_00776 1.2e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
IICANBEH_00777 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IICANBEH_00778 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IICANBEH_00779 3.7e-85 ccl S cog cog4708
IICANBEH_00780 7.4e-164 rbn E Belongs to the UPF0761 family
IICANBEH_00781 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IICANBEH_00782 3.3e-231 ytoI K transcriptional regulator containing CBS domains
IICANBEH_00783 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
IICANBEH_00784 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IICANBEH_00785 0.0 comEC S Competence protein ComEC
IICANBEH_00786 7.5e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IICANBEH_00787 1.1e-140 Z012_04635 K Helix-turn-helix XRE-family like proteins
IICANBEH_00789 2.7e-112 C 4Fe-4S single cluster domain
IICANBEH_00790 1.6e-52 C Iron-sulfur cluster-binding domain
IICANBEH_00792 4.1e-156 V AAA domain, putative AbiEii toxin, Type IV TA system
IICANBEH_00793 8.9e-56 V ABC-2 type transporter
IICANBEH_00794 2.8e-97
IICANBEH_00795 1.1e-23
IICANBEH_00796 1.9e-141 plsC 2.3.1.51 I Acyltransferase
IICANBEH_00797 5.4e-79 nodB3 G polysaccharide deacetylase
IICANBEH_00798 5.9e-48 nodB3 G polysaccharide deacetylase
IICANBEH_00799 2.7e-140 yabB 2.1.1.223 L Methyltransferase
IICANBEH_00800 1e-41 yazA L endonuclease containing a URI domain
IICANBEH_00801 1.3e-237 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IICANBEH_00802 6.7e-154 corA P CorA-like protein
IICANBEH_00803 2.5e-62 yjqA S Bacterial PH domain
IICANBEH_00804 5.6e-98 thiT S Thiamine transporter
IICANBEH_00805 5.7e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IICANBEH_00806 2.7e-200 yjbB G Permeases of the major facilitator superfamily
IICANBEH_00807 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IICANBEH_00808 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
IICANBEH_00809 1.5e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IICANBEH_00813 1.1e-155 cjaA ET ABC transporter substrate-binding protein
IICANBEH_00814 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IICANBEH_00815 1.3e-114 P ABC transporter (Permease
IICANBEH_00816 6.6e-114 papP P ABC transporter (Permease
IICANBEH_00817 1.9e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IICANBEH_00818 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
IICANBEH_00819 0.0 copA 3.6.3.54 P P-type ATPase
IICANBEH_00820 2.7e-73 copY K Copper transport repressor, CopY TcrY family
IICANBEH_00821 4.6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IICANBEH_00822 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IICANBEH_00823 5.5e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
IICANBEH_00824 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IICANBEH_00825 1.3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IICANBEH_00826 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
IICANBEH_00827 6.9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IICANBEH_00828 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
IICANBEH_00829 1.7e-51
IICANBEH_00830 0.0 ctpE P E1-E2 ATPase
IICANBEH_00831 3.9e-26
IICANBEH_00832 7e-32 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IICANBEH_00833 3.3e-46 L transposase activity
IICANBEH_00834 9.2e-122 K transcriptional regulator, MerR family
IICANBEH_00835 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
IICANBEH_00836 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
IICANBEH_00837 1.6e-63 XK27_02560 S cog cog2151
IICANBEH_00838 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IICANBEH_00839 7.7e-227 ytfP S Flavoprotein
IICANBEH_00841 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IICANBEH_00842 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
IICANBEH_00843 2.7e-183 ecsB U ABC transporter
IICANBEH_00844 2.3e-133 ecsA V abc transporter atp-binding protein
IICANBEH_00845 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IICANBEH_00846 2.3e-10
IICANBEH_00847 2.7e-57 S CD20-like family
IICANBEH_00848 4.7e-106
IICANBEH_00849 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
IICANBEH_00850 6.9e-206 ylbM S Belongs to the UPF0348 family
IICANBEH_00851 2e-140 yqeM Q Methyltransferase domain protein
IICANBEH_00852 3e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IICANBEH_00853 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IICANBEH_00854 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IICANBEH_00855 3.5e-49 yhbY J RNA-binding protein
IICANBEH_00856 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IICANBEH_00857 1.8e-98 yqeG S hydrolase of the HAD superfamily
IICANBEH_00858 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IICANBEH_00859 6.2e-51
IICANBEH_00860 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IICANBEH_00861 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IICANBEH_00862 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IICANBEH_00863 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
IICANBEH_00864 1e-148 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IICANBEH_00865 4.3e-97 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IICANBEH_00866 1.4e-86 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IICANBEH_00867 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
IICANBEH_00868 6.8e-101 pncA Q isochorismatase
IICANBEH_00869 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IICANBEH_00870 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
IICANBEH_00871 2.4e-75 XK27_03180 T universal stress protein
IICANBEH_00874 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IICANBEH_00875 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
IICANBEH_00876 4.6e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
IICANBEH_00877 0.0 yjcE P NhaP-type Na H and K H antiporters
IICANBEH_00879 1.8e-98 ytqB 2.1.1.176 J (SAM)-dependent
IICANBEH_00880 1.3e-184 yhcC S radical SAM protein
IICANBEH_00881 2.2e-196 ylbL T Belongs to the peptidase S16 family
IICANBEH_00882 5.9e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IICANBEH_00883 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
IICANBEH_00884 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IICANBEH_00885 1.9e-09 S Protein of unknown function (DUF4059)
IICANBEH_00886 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
IICANBEH_00887 1e-162 yxeN P ABC transporter (Permease
IICANBEH_00888 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IICANBEH_00890 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IICANBEH_00891 0.0 pflB 2.3.1.54 C formate acetyltransferase'
IICANBEH_00892 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
IICANBEH_00893 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IICANBEH_00894 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
IICANBEH_00895 2.9e-87 D nuclear chromosome segregation
IICANBEH_00896 4.4e-127 ybbM S transport system, permease component
IICANBEH_00897 2.1e-117 ybbL S abc transporter atp-binding protein
IICANBEH_00898 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
IICANBEH_00899 4.6e-140 cppA E CppA N-terminal
IICANBEH_00900 5e-44 V CAAX protease self-immunity
IICANBEH_00901 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IICANBEH_00902 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IICANBEH_00905 3e-47 spiA K sequence-specific DNA binding
IICANBEH_00906 2.9e-28 blpT
IICANBEH_00907 6.7e-98 blpT
IICANBEH_00914 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
IICANBEH_00918 7.4e-135 agrA KT phosphorelay signal transduction system
IICANBEH_00919 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
IICANBEH_00921 7.3e-237 mesE M Transport protein ComB
IICANBEH_00922 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IICANBEH_00923 0.0 mdlB V abc transporter atp-binding protein
IICANBEH_00924 0.0 mdlA V abc transporter atp-binding protein
IICANBEH_00926 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
IICANBEH_00927 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IICANBEH_00928 2.4e-66 yutD J protein conserved in bacteria
IICANBEH_00929 6.7e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IICANBEH_00931 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IICANBEH_00932 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IICANBEH_00933 0.0 ftsI 3.4.16.4 M penicillin-binding protein
IICANBEH_00934 4.3e-47 ftsL D cell division protein FtsL
IICANBEH_00935 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IICANBEH_00936 3e-128
IICANBEH_00937 9.7e-32 yhaI J Protein of unknown function (DUF805)
IICANBEH_00938 1.3e-08 D nuclear chromosome segregation
IICANBEH_00939 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IICANBEH_00940 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IICANBEH_00941 2.2e-285 XK27_00765
IICANBEH_00942 8.1e-134 ecsA_2 V abc transporter atp-binding protein
IICANBEH_00943 5.2e-125 S Protein of unknown function (DUF554)
IICANBEH_00944 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IICANBEH_00945 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IICANBEH_00946 5.7e-121 liaI S membrane
IICANBEH_00947 1.2e-74 XK27_02470 K LytTr DNA-binding domain
IICANBEH_00948 7e-70 KT response to antibiotic
IICANBEH_00949 2.6e-80 yebC M Membrane
IICANBEH_00950 2.9e-18 yebC M Membrane
IICANBEH_00951 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
IICANBEH_00952 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IICANBEH_00953 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IICANBEH_00954 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IICANBEH_00955 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IICANBEH_00956 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IICANBEH_00957 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IICANBEH_00958 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IICANBEH_00960 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
IICANBEH_00961 1.6e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
IICANBEH_00962 0.0 scrA 2.7.1.211 G pts system
IICANBEH_00963 5.4e-291 scrB 3.2.1.26 GH32 G invertase
IICANBEH_00964 7.5e-180 scrR K Transcriptional
IICANBEH_00965 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IICANBEH_00966 3.4e-62 yqhY S protein conserved in bacteria
IICANBEH_00967 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IICANBEH_00968 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
IICANBEH_00969 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
IICANBEH_00971 1.4e-43 V 'abc transporter, ATP-binding protein
IICANBEH_00972 1e-58 V 'abc transporter, ATP-binding protein
IICANBEH_00975 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IICANBEH_00976 2e-169 corA P COG0598 Mg2 and Co2 transporters
IICANBEH_00977 3.1e-124 XK27_01040 S Pfam PF06570
IICANBEH_00979 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IICANBEH_00980 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IICANBEH_00981 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
IICANBEH_00982 3.6e-41 XK27_05745
IICANBEH_00983 2.5e-230 mutY L A G-specific adenine glycosylase
IICANBEH_00990 0.0 spoVK O stage V sporulation protein K
IICANBEH_00992 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IICANBEH_00993 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IICANBEH_00994 1e-93 cvpA S toxin biosynthetic process
IICANBEH_00995 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IICANBEH_00996 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IICANBEH_00997 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IICANBEH_00998 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IICANBEH_00999 2e-47 azlD E branched-chain amino acid
IICANBEH_01000 1.8e-114 azlC E AzlC protein
IICANBEH_01001 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IICANBEH_01002 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IICANBEH_01003 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
IICANBEH_01004 2.5e-33 ykzG S Belongs to the UPF0356 family
IICANBEH_01005 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IICANBEH_01006 2.7e-40 pscB M CHAP domain protein
IICANBEH_01007 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
IICANBEH_01008 8.5e-63 glnR K Transcriptional regulator
IICANBEH_01009 1.3e-87 S Fusaric acid resistance protein-like
IICANBEH_01010 3e-13
IICANBEH_01011 8.9e-30
IICANBEH_01012 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IICANBEH_01013 3.2e-42 L Transposase
IICANBEH_01018 2.6e-10
IICANBEH_01021 1.9e-07
IICANBEH_01026 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IICANBEH_01027 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IICANBEH_01028 5.5e-36 XK27_02060 S Transglycosylase associated protein
IICANBEH_01029 2.6e-55 badR K DNA-binding transcription factor activity
IICANBEH_01030 3.5e-97 S reductase
IICANBEH_01031 1.2e-32 L Integrase core domain protein
IICANBEH_01033 4.7e-174 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IICANBEH_01035 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
IICANBEH_01036 3e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IICANBEH_01037 9.3e-83 S Putative small multi-drug export protein
IICANBEH_01038 6.2e-76 ctsR K Belongs to the CtsR family
IICANBEH_01039 0.0 clpC O Belongs to the ClpA ClpB family
IICANBEH_01040 6.6e-130 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IICANBEH_01041 3.9e-59 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IICANBEH_01042 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IICANBEH_01043 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IICANBEH_01044 2e-143 S SseB protein N-terminal domain
IICANBEH_01045 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
IICANBEH_01046 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IICANBEH_01047 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IICANBEH_01050 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IICANBEH_01051 3.5e-91 yacP S RNA-binding protein containing a PIN domain
IICANBEH_01052 4.4e-155 degV S DegV family
IICANBEH_01054 1.8e-31 K helix-turn-helix
IICANBEH_01055 4.7e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IICANBEH_01056 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IICANBEH_01057 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IICANBEH_01058 1.5e-35 K sequence-specific DNA binding
IICANBEH_01060 0.0 S Lantibiotic dehydratase, C terminus
IICANBEH_01061 2.4e-231 spaC2 V Lanthionine synthetase C family protein
IICANBEH_01062 5.6e-183 EGP Major facilitator Superfamily
IICANBEH_01063 5.9e-24 3.6.4.12
IICANBEH_01064 5.9e-91 3.6.4.12 K Divergent AAA domain protein
IICANBEH_01065 8.2e-224 int L Belongs to the 'phage' integrase family
IICANBEH_01066 1.8e-38 S Helix-turn-helix domain
IICANBEH_01067 4.9e-173
IICANBEH_01069 3.4e-75 isp2 S pathogenesis
IICANBEH_01070 5.7e-91 tnp L Transposase
IICANBEH_01071 3.3e-225 capA M Bacterial capsule synthesis protein
IICANBEH_01072 3.6e-39 gcvR T UPF0237 protein
IICANBEH_01073 1.9e-242 XK27_08635 S UPF0210 protein
IICANBEH_01074 4.8e-38 ais G alpha-ribazole phosphatase activity
IICANBEH_01075 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IICANBEH_01076 3.8e-102 acmA 3.2.1.17 NU amidase activity
IICANBEH_01077 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IICANBEH_01078 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IICANBEH_01079 9.8e-298 dnaK O Heat shock 70 kDa protein
IICANBEH_01080 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IICANBEH_01081 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IICANBEH_01082 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
IICANBEH_01083 1.7e-60 hmpT S membrane
IICANBEH_01084 1e-187 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IICANBEH_01085 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IICANBEH_01086 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IICANBEH_01087 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IICANBEH_01088 1.1e-142 purR 2.4.2.7 F operon repressor
IICANBEH_01089 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
IICANBEH_01090 6.9e-173 rmuC S RmuC domain protein
IICANBEH_01091 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
IICANBEH_01092 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IICANBEH_01093 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IICANBEH_01095 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IICANBEH_01096 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IICANBEH_01097 4.1e-144 tatD L Hydrolase, tatd
IICANBEH_01098 7.2e-74 yccU S CoA-binding protein
IICANBEH_01099 4.8e-51 trxA O Belongs to the thioredoxin family
IICANBEH_01100 1.9e-141 S Macro domain protein
IICANBEH_01101 2e-09 L thioesterase
IICANBEH_01102 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
IICANBEH_01104 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IICANBEH_01105 2.3e-33 L Transposase
IICANBEH_01106 1e-13 rpmH J Ribosomal protein L34
IICANBEH_01107 7.6e-186 jag S RNA-binding protein
IICANBEH_01108 8.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IICANBEH_01109 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IICANBEH_01110 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
IICANBEH_01111 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IICANBEH_01112 6e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IICANBEH_01113 2e-20 amiA E ABC transporter, substrate-binding protein, family 5
IICANBEH_01114 6.6e-63 amiA E transmembrane transport
IICANBEH_01115 4.2e-74 amiA E transmembrane transport
IICANBEH_01116 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IICANBEH_01117 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IICANBEH_01118 9.2e-51 S Protein of unknown function (DUF3397)
IICANBEH_01119 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IICANBEH_01120 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
IICANBEH_01121 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
IICANBEH_01122 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
IICANBEH_01123 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IICANBEH_01124 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IICANBEH_01125 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
IICANBEH_01126 4.3e-77 XK27_09620 S reductase
IICANBEH_01127 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
IICANBEH_01128 3.7e-116 XK27_09615 C reductase
IICANBEH_01129 3.2e-62 fnt P Formate nitrite transporter
IICANBEH_01130 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
IICANBEH_01131 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IICANBEH_01132 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IICANBEH_01133 1.2e-165 L integrase core domain
IICANBEH_01134 1.1e-121 L Transposase
IICANBEH_01135 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IICANBEH_01136 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IICANBEH_01137 1.3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IICANBEH_01138 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IICANBEH_01139 1.6e-21 S glycolate biosynthetic process
IICANBEH_01140 3.8e-60 S phosphatase activity
IICANBEH_01141 3.5e-157 rrmA 2.1.1.187 Q methyltransferase
IICANBEH_01144 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IICANBEH_01145 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IICANBEH_01146 6.4e-37 yeeD O sulfur carrier activity
IICANBEH_01147 1.3e-190 yeeE S Sulphur transport
IICANBEH_01148 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IICANBEH_01149 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IICANBEH_01150 3.2e-09 S Domain of unknown function (DUF4651)
IICANBEH_01151 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IICANBEH_01152 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IICANBEH_01153 1.8e-111 S CAAX amino terminal protease family protein
IICANBEH_01155 7.2e-66 V CAAX protease self-immunity
IICANBEH_01156 2.3e-33 V CAAX protease self-immunity
IICANBEH_01157 2.6e-26 lanR K sequence-specific DNA binding
IICANBEH_01158 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IICANBEH_01159 5.9e-177 ytxK 2.1.1.72 L DNA methylase
IICANBEH_01160 6.8e-13 comGF U Putative Competence protein ComGF
IICANBEH_01161 1.1e-69 comGF U Competence protein ComGF
IICANBEH_01162 4.1e-15 NU Type II secretory pathway pseudopilin
IICANBEH_01163 4e-57 cglD NU Competence protein
IICANBEH_01164 8.5e-43 comGC U Required for transformation and DNA binding
IICANBEH_01165 3e-145 cglB NU type II secretion system
IICANBEH_01166 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IICANBEH_01167 1e-68 S cog cog4699
IICANBEH_01168 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IICANBEH_01169 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IICANBEH_01170 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IICANBEH_01171 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IICANBEH_01172 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IICANBEH_01173 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
IICANBEH_01174 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
IICANBEH_01175 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IICANBEH_01176 2.9e-304 yloV S kinase related to dihydroxyacetone kinase
IICANBEH_01177 1.4e-57 asp S cog cog1302
IICANBEH_01178 3.2e-226 norN V Mate efflux family protein
IICANBEH_01179 5.4e-278 thrC 4.2.3.1 E Threonine synthase
IICANBEH_01180 1.6e-64 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IICANBEH_01181 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
IICANBEH_01182 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IICANBEH_01183 2.6e-136 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IICANBEH_01184 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
IICANBEH_01185 0.0 pepO 3.4.24.71 O Peptidase family M13
IICANBEH_01186 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IICANBEH_01187 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IICANBEH_01188 5.6e-64 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IICANBEH_01189 2.4e-54 treB 2.7.1.201 G PTS System
IICANBEH_01190 5.8e-21 treR K DNA-binding transcription factor activity
IICANBEH_01191 5.6e-86 treR K trehalose operon
IICANBEH_01192 3.3e-95 ywlG S Belongs to the UPF0340 family
IICANBEH_01194 3.3e-09 L PFAM Integrase, catalytic core
IICANBEH_01195 5.3e-111 L PFAM Integrase, catalytic core
IICANBEH_01196 1.5e-207 L Transposase
IICANBEH_01197 3.1e-87 L Phage integrase family
IICANBEH_01198 5.7e-46 S Domain of unknown function (DUF4298)
IICANBEH_01199 2.9e-122 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IICANBEH_01200 2.6e-16 tnp L Transposase IS66 family
IICANBEH_01201 5.8e-126 tnp L DDE domain
IICANBEH_01203 1.6e-21
IICANBEH_01205 1.3e-146 S Abortive infection C-terminus
IICANBEH_01206 5.1e-111 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
IICANBEH_01207 3.2e-300 hsdM 2.1.1.72 V HsdM N-terminal domain
IICANBEH_01208 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IICANBEH_01209 2.4e-26
IICANBEH_01210 8.6e-140 L DNA integration
IICANBEH_01211 1.8e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
IICANBEH_01213 3.6e-147 6.3.2.2 H gamma-glutamylcysteine synthetase
IICANBEH_01214 2.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
IICANBEH_01215 2.7e-13 L PFAM Integrase, catalytic core
IICANBEH_01216 1.8e-111 L PFAM Integrase, catalytic core
IICANBEH_01217 3.3e-62 rplQ J ribosomal protein l17
IICANBEH_01218 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IICANBEH_01219 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IICANBEH_01220 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IICANBEH_01221 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IICANBEH_01222 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IICANBEH_01223 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IICANBEH_01224 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IICANBEH_01225 4.4e-58 rplO J binds to the 23S rRNA
IICANBEH_01226 2.5e-23 rpmD J ribosomal protein l30
IICANBEH_01227 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IICANBEH_01228 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IICANBEH_01229 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IICANBEH_01230 1.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IICANBEH_01231 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IICANBEH_01232 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IICANBEH_01233 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IICANBEH_01234 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IICANBEH_01235 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IICANBEH_01236 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
IICANBEH_01237 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IICANBEH_01238 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IICANBEH_01239 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IICANBEH_01240 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IICANBEH_01241 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IICANBEH_01242 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IICANBEH_01243 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
IICANBEH_01244 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IICANBEH_01245 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
IICANBEH_01246 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IICANBEH_01247 0.0 XK27_09800 I Acyltransferase
IICANBEH_01248 1.7e-35 XK27_09805 S MORN repeat protein
IICANBEH_01249 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IICANBEH_01250 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IICANBEH_01251 8.8e-83 adk 2.7.4.3 F topology modulation protein
IICANBEH_01252 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
IICANBEH_01254 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IICANBEH_01256 1.5e-162 hrtB V MacB-like periplasmic core domain
IICANBEH_01257 3.1e-116 devA 3.6.3.25 V abc transporter atp-binding protein
IICANBEH_01258 1.6e-249 L Transposase
IICANBEH_01260 9.9e-19 S Domain of unknown function (DUF4649)
IICANBEH_01261 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
IICANBEH_01262 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IICANBEH_01263 1e-84
IICANBEH_01264 1.6e-77 sigH K DNA-templated transcription, initiation
IICANBEH_01265 3e-148 ykuT M mechanosensitive ion channel
IICANBEH_01266 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IICANBEH_01267 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IICANBEH_01268 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IICANBEH_01269 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
IICANBEH_01270 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IICANBEH_01271 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
IICANBEH_01272 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IICANBEH_01273 1.4e-42 F nucleotide catabolic process
IICANBEH_01274 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IICANBEH_01275 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IICANBEH_01276 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IICANBEH_01277 1.8e-83 nrdI F Belongs to the NrdI family
IICANBEH_01278 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IICANBEH_01279 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IICANBEH_01280 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IICANBEH_01281 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IICANBEH_01282 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IICANBEH_01283 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IICANBEH_01284 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IICANBEH_01285 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IICANBEH_01286 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IICANBEH_01287 6.5e-202 yhjX P Major Facilitator
IICANBEH_01288 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IICANBEH_01289 5e-94 V VanZ like family
IICANBEH_01292 1e-123 glnQ E abc transporter atp-binding protein
IICANBEH_01293 9e-276 glnP P ABC transporter
IICANBEH_01294 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IICANBEH_01295 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IICANBEH_01296 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
IICANBEH_01297 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IICANBEH_01298 6.3e-235 sufD O assembly protein SufD
IICANBEH_01299 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IICANBEH_01300 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
IICANBEH_01301 2.2e-273 sufB O assembly protein SufB
IICANBEH_01302 7e-10 oppA E ABC transporter substrate-binding protein
IICANBEH_01303 3.3e-138 oppA E ABC transporter substrate-binding protein
IICANBEH_01304 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICANBEH_01305 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICANBEH_01306 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICANBEH_01307 9.8e-40 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IICANBEH_01308 8e-28 oppD P Belongs to the ABC transporter superfamily
IICANBEH_01309 2.5e-32 oppD P Belongs to the ABC transporter superfamily
IICANBEH_01310 4.8e-67 oppD P Belongs to the ABC transporter superfamily
IICANBEH_01311 1.3e-44 oppD P Belongs to the ABC transporter superfamily
IICANBEH_01312 9e-170 oppF P Belongs to the ABC transporter superfamily
IICANBEH_01315 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IICANBEH_01316 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IICANBEH_01317 1.9e-223 EGP Major facilitator Superfamily
IICANBEH_01318 3.1e-72 adcR K transcriptional
IICANBEH_01319 6.4e-136 adcC P ABC transporter, ATP-binding protein
IICANBEH_01320 4.6e-130 adcB P ABC transporter (Permease
IICANBEH_01321 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IICANBEH_01322 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
IICANBEH_01323 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
IICANBEH_01324 3.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IICANBEH_01325 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
IICANBEH_01326 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
IICANBEH_01327 1.9e-127 yeeN K transcriptional regulatory protein
IICANBEH_01328 9.8e-50 yajC U protein transport
IICANBEH_01329 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IICANBEH_01330 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
IICANBEH_01331 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IICANBEH_01332 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IICANBEH_01333 0.0 WQ51_06230 S ABC transporter substrate binding protein
IICANBEH_01334 5.2e-142 cmpC S abc transporter atp-binding protein
IICANBEH_01335 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IICANBEH_01336 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IICANBEH_01337 2e-126 KLT serine threonine protein kinase
IICANBEH_01338 1.7e-66 V ABC transporter
IICANBEH_01339 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IICANBEH_01340 6.7e-87 Z012_04635 K sequence-specific DNA binding
IICANBEH_01341 2e-25 Z012_04635 K sequence-specific DNA binding
IICANBEH_01343 1.6e-53 C Radical SAM
IICANBEH_01344 1.3e-156 C Radical SAM
IICANBEH_01345 3.9e-287 V ABC transporter transmembrane region
IICANBEH_01346 4.4e-89 K sequence-specific DNA binding
IICANBEH_01347 1e-36 L Replication initiation factor
IICANBEH_01348 1.4e-107 L Replication initiation factor
IICANBEH_01349 1.9e-18 S Domain of unknown function (DUF3173)
IICANBEH_01350 3.5e-216 int L Belongs to the 'phage' integrase family
IICANBEH_01352 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
IICANBEH_01353 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IICANBEH_01354 2.8e-44 yrzL S Belongs to the UPF0297 family
IICANBEH_01355 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IICANBEH_01356 4.2e-44 yrzB S Belongs to the UPF0473 family
IICANBEH_01357 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
IICANBEH_01358 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IICANBEH_01359 7.5e-14
IICANBEH_01360 2.6e-91 XK27_10930 K acetyltransferase
IICANBEH_01361 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IICANBEH_01362 1.8e-147 yaaA S Belongs to the UPF0246 family
IICANBEH_01363 9.9e-169 XK27_01785 S cog cog1284
IICANBEH_01364 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IICANBEH_01366 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
IICANBEH_01367 5.7e-52 metE 2.1.1.14 E Methionine synthase
IICANBEH_01368 7.6e-64 metE 2.1.1.14 E Methionine synthase
IICANBEH_01369 9.2e-36 metE 2.1.1.14 E Methionine synthase
IICANBEH_01370 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IICANBEH_01371 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IICANBEH_01373 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
IICANBEH_01374 2.7e-95 S Hydrophobic domain protein
IICANBEH_01376 3.7e-27 S Membrane
IICANBEH_01377 3.1e-101
IICANBEH_01378 1.8e-23 S Small integral membrane protein
IICANBEH_01379 3.1e-85 M Protein conserved in bacteria
IICANBEH_01380 1.1e-11 K CsbD-like
IICANBEH_01381 3.4e-13 nudL L hydrolase
IICANBEH_01382 4e-19 K negative regulation of transcription, DNA-templated
IICANBEH_01383 1.7e-23 K negative regulation of transcription, DNA-templated
IICANBEH_01385 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
IICANBEH_01386 1.8e-88 S Putative adhesin
IICANBEH_01387 3.9e-161 XK27_06930 V domain protein
IICANBEH_01388 6.4e-96 XK27_06935 K transcriptional regulator
IICANBEH_01389 1.8e-54 ypaA M Membrane
IICANBEH_01390 2.7e-08
IICANBEH_01391 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IICANBEH_01392 8.2e-48 veg S Biofilm formation stimulator VEG
IICANBEH_01393 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IICANBEH_01394 3.9e-70 rplI J binds to the 23S rRNA
IICANBEH_01395 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IICANBEH_01396 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IICANBEH_01397 1.5e-77 F NUDIX domain
IICANBEH_01398 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IICANBEH_01399 0.0 S Bacterial membrane protein, YfhO
IICANBEH_01400 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
IICANBEH_01401 3.1e-93 lytE M LysM domain protein
IICANBEH_01402 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IICANBEH_01403 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IICANBEH_01404 2.2e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IICANBEH_01405 6.9e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IICANBEH_01406 3.7e-138 ymfM S sequence-specific DNA binding
IICANBEH_01407 1.4e-242 ymfH S Peptidase M16
IICANBEH_01408 1.4e-234 ymfF S Peptidase M16
IICANBEH_01409 1.6e-45 yaaA S S4 domain protein YaaA
IICANBEH_01410 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IICANBEH_01411 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IICANBEH_01412 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IICANBEH_01413 1.1e-153 yvjA S membrane
IICANBEH_01414 6.7e-306 ybiT S abc transporter atp-binding protein
IICANBEH_01415 0.0 XK27_10405 S Bacterial membrane protein YfhO
IICANBEH_01419 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
IICANBEH_01420 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IICANBEH_01421 5.3e-194 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IICANBEH_01422 8.5e-134 parB K Belongs to the ParB family
IICANBEH_01423 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IICANBEH_01424 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IICANBEH_01425 1.1e-29 yyzM S Protein conserved in bacteria
IICANBEH_01426 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IICANBEH_01427 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IICANBEH_01428 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IICANBEH_01429 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IICANBEH_01430 7.9e-61 divIC D Septum formation initiator
IICANBEH_01432 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
IICANBEH_01433 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IICANBEH_01434 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IICANBEH_01435 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IICANBEH_01436 1.7e-162 L Transposase
IICANBEH_01437 4.4e-37 L Transposase
IICANBEH_01438 6.4e-18 L transposase activity
IICANBEH_01441 2.1e-43
IICANBEH_01442 2.9e-54 S TM2 domain
IICANBEH_01443 5.8e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IICANBEH_01444 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IICANBEH_01445 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
IICANBEH_01446 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
IICANBEH_01447 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
IICANBEH_01448 6e-55 cof Q phosphatase activity
IICANBEH_01449 1.1e-34 cof Q phosphatase activity
IICANBEH_01450 1.5e-135 glcR K transcriptional regulator (DeoR family)
IICANBEH_01451 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IICANBEH_01452 3.8e-40 K transcriptional
IICANBEH_01454 2.6e-76 S thiolester hydrolase activity
IICANBEH_01455 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
IICANBEH_01456 9.6e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IICANBEH_01457 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IICANBEH_01458 3.9e-57 yhaI L Membrane
IICANBEH_01459 4.6e-260 pepC 3.4.22.40 E aminopeptidase
IICANBEH_01460 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IICANBEH_01461 2.4e-107 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IICANBEH_01462 4.9e-93 ypsA S Belongs to the UPF0398 family
IICANBEH_01463 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IICANBEH_01464 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IICANBEH_01465 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IICANBEH_01466 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IICANBEH_01467 2.9e-41 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IICANBEH_01468 2.5e-23
IICANBEH_01469 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IICANBEH_01470 7.3e-80 XK27_09675 K -acetyltransferase
IICANBEH_01471 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IICANBEH_01472 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IICANBEH_01473 7.1e-46 L Integrase core domain protein
IICANBEH_01474 1.6e-32 L Integrase core domain protein
IICANBEH_01475 3.8e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IICANBEH_01476 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IICANBEH_01477 1.9e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IICANBEH_01478 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
IICANBEH_01479 1.5e-97 ybhL S Belongs to the BI1 family
IICANBEH_01482 1.8e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IICANBEH_01483 3.4e-89 K transcriptional regulator
IICANBEH_01484 7.6e-36 yneF S UPF0154 protein
IICANBEH_01485 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IICANBEH_01486 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IICANBEH_01487 3.5e-99 XK27_09740 S Phosphoesterase
IICANBEH_01488 5.4e-86 ykuL S CBS domain
IICANBEH_01489 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IICANBEH_01490 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IICANBEH_01491 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IICANBEH_01492 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IICANBEH_01493 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IICANBEH_01494 1.2e-258 trkH P Cation transport protein
IICANBEH_01495 1.5e-247 trkA P Potassium transporter peripheral membrane component
IICANBEH_01496 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IICANBEH_01497 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IICANBEH_01498 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
IICANBEH_01499 5.6e-161 K sequence-specific DNA binding
IICANBEH_01500 1.2e-32 V protein secretion by the type I secretion system
IICANBEH_01501 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IICANBEH_01502 1.3e-56 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IICANBEH_01503 1.6e-25 V protein secretion by the type I secretion system
IICANBEH_01504 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IICANBEH_01505 3.7e-22 yhaI L Membrane
IICANBEH_01506 1.4e-54 S Domain of unknown function (DUF4173)
IICANBEH_01507 6.8e-95 ureI S AmiS/UreI family transporter
IICANBEH_01508 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IICANBEH_01509 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IICANBEH_01510 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IICANBEH_01511 6.6e-78 ureE O enzyme active site formation
IICANBEH_01512 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IICANBEH_01513 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IICANBEH_01514 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IICANBEH_01515 2.3e-176 cbiM P PDGLE domain
IICANBEH_01516 1.1e-136 P cobalt transport protein
IICANBEH_01517 1.6e-131 cbiO P ABC transporter
IICANBEH_01518 5.3e-153 ET amino acid transport
IICANBEH_01519 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IICANBEH_01520 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
IICANBEH_01521 3.8e-205 EGP Transmembrane secretion effector
IICANBEH_01522 4e-153 ET amino acid transport
IICANBEH_01523 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
IICANBEH_01524 1.6e-85 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IICANBEH_01525 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IICANBEH_01526 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IICANBEH_01527 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IICANBEH_01528 2e-97 metI P ABC transporter (Permease
IICANBEH_01529 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IICANBEH_01530 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
IICANBEH_01531 8e-94 S UPF0397 protein
IICANBEH_01532 0.0 ykoD P abc transporter atp-binding protein
IICANBEH_01533 5.9e-149 cbiQ P cobalt transport
IICANBEH_01534 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IICANBEH_01535 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
IICANBEH_01536 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
IICANBEH_01537 3.4e-242 P COG0168 Trk-type K transport systems, membrane components
IICANBEH_01538 1.4e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
IICANBEH_01539 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
IICANBEH_01540 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IICANBEH_01541 2.8e-282 T PhoQ Sensor
IICANBEH_01542 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IICANBEH_01543 1.6e-216 dnaB L Replication initiation and membrane attachment
IICANBEH_01544 5.2e-167 dnaI L Primosomal protein DnaI
IICANBEH_01545 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IICANBEH_01547 2.7e-34
IICANBEH_01548 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
IICANBEH_01549 3e-27 L Integrase core domain protein
IICANBEH_01550 6.9e-09 L transposition
IICANBEH_01551 5.7e-23 L Transposase
IICANBEH_01552 1.2e-40 L transposase activity
IICANBEH_01553 3.3e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IICANBEH_01554 4.2e-62 manO S protein conserved in bacteria
IICANBEH_01555 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
IICANBEH_01556 2.3e-116 manM G pts system
IICANBEH_01557 1.1e-181 manL 2.7.1.191 G pts system
IICANBEH_01558 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
IICANBEH_01559 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IICANBEH_01560 2.1e-247 pbuO S permease
IICANBEH_01561 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
IICANBEH_01562 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
IICANBEH_01563 2.5e-220 brpA K Transcriptional
IICANBEH_01564 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
IICANBEH_01565 3.1e-212 nusA K Participates in both transcription termination and antitermination
IICANBEH_01566 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
IICANBEH_01567 1.4e-41 ylxQ J ribosomal protein
IICANBEH_01568 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IICANBEH_01569 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IICANBEH_01570 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
IICANBEH_01571 8.9e-38 yvdD 3.2.2.10 L Belongs to the LOG family
IICANBEH_01572 4.1e-234 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IICANBEH_01573 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IICANBEH_01574 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
IICANBEH_01575 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
IICANBEH_01576 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
IICANBEH_01577 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IICANBEH_01579 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IICANBEH_01580 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IICANBEH_01581 3.4e-74 ylbF S Belongs to the UPF0342 family
IICANBEH_01582 7.1e-46 ylbG S UPF0298 protein
IICANBEH_01583 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IICANBEH_01584 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
IICANBEH_01585 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
IICANBEH_01586 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IICANBEH_01587 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IICANBEH_01588 2.8e-70 acuB S IMP dehydrogenase activity
IICANBEH_01589 3.3e-43 acuB S IMP dehydrogenase activity
IICANBEH_01590 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IICANBEH_01591 6.3e-111 yvyE 3.4.13.9 S YigZ family
IICANBEH_01592 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IICANBEH_01593 4.4e-123 comFC S Competence protein
IICANBEH_01594 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IICANBEH_01601 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
IICANBEH_01602 6.4e-108 S Domain of unknown function (DUF1803)
IICANBEH_01603 1.3e-101 ygaC J Belongs to the UPF0374 family
IICANBEH_01604 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
IICANBEH_01605 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IICANBEH_01606 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
IICANBEH_01607 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
IICANBEH_01608 2.1e-114 S Haloacid dehalogenase-like hydrolase
IICANBEH_01609 4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
IICANBEH_01610 4e-72 marR K Transcriptional regulator, MarR family
IICANBEH_01611 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IICANBEH_01612 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IICANBEH_01613 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
IICANBEH_01614 1.9e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IICANBEH_01615 1.6e-126 IQ reductase
IICANBEH_01616 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IICANBEH_01617 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IICANBEH_01618 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IICANBEH_01619 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IICANBEH_01620 1.1e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IICANBEH_01621 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IICANBEH_01622 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IICANBEH_01623 1.1e-92 tnp L Transposase
IICANBEH_01624 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
IICANBEH_01625 1.8e-84 L Transposase
IICANBEH_01626 5.6e-114 fruR K transcriptional
IICANBEH_01627 5.5e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IICANBEH_01628 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
IICANBEH_01629 2.2e-49 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
IICANBEH_01630 2.7e-126 fruA 2.7.1.202 G phosphotransferase system
IICANBEH_01631 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
IICANBEH_01632 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IICANBEH_01633 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IICANBEH_01635 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IICANBEH_01636 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IICANBEH_01637 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IICANBEH_01638 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IICANBEH_01639 6.4e-29 2.3.1.128 K acetyltransferase
IICANBEH_01640 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IICANBEH_01641 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IICANBEH_01642 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IICANBEH_01643 2.6e-64 WQ51_03320 S cog cog4835
IICANBEH_01644 5.8e-144 XK27_08360 S EDD domain protein, DegV family
IICANBEH_01645 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IICANBEH_01646 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IICANBEH_01647 0.0 yfmR S abc transporter atp-binding protein
IICANBEH_01648 1.6e-24 U response to pH
IICANBEH_01649 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
IICANBEH_01650 4.7e-128 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IICANBEH_01651 2.6e-59 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IICANBEH_01652 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IICANBEH_01653 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IICANBEH_01654 1.9e-77 K DNA-binding transcription factor activity
IICANBEH_01655 0.0 lmrA1 V abc transporter atp-binding protein
IICANBEH_01656 0.0 lmrA2 V abc transporter atp-binding protein
IICANBEH_01657 2.2e-18 K Acetyltransferase (GNAT) family
IICANBEH_01658 3.2e-78 sptS 2.7.13.3 T Histidine kinase
IICANBEH_01659 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IICANBEH_01660 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IICANBEH_01661 5.3e-161 cvfB S Protein conserved in bacteria
IICANBEH_01662 1.6e-34 yozE S Belongs to the UPF0346 family
IICANBEH_01663 5.1e-119 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
IICANBEH_01665 3e-61 rlpA M LysM domain protein
IICANBEH_01666 8e-191 phoH T phosphate starvation-inducible protein PhoH
IICANBEH_01670 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IICANBEH_01671 1.8e-164 K transcriptional regulator (lysR family)
IICANBEH_01672 1.4e-186 coiA 3.6.4.12 S Competence protein
IICANBEH_01673 0.0 pepF E oligoendopeptidase F
IICANBEH_01674 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
IICANBEH_01675 2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
IICANBEH_01676 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IICANBEH_01677 7.3e-50 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IICANBEH_01678 7e-124 tnp L DDE domain
IICANBEH_01679 3.7e-88 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IICANBEH_01680 3.4e-41 3.4.17.14, 3.5.1.28 NU amidase activity
IICANBEH_01681 1.3e-30 3.4.17.14, 3.5.1.28 NU amidase activity
IICANBEH_01682 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IICANBEH_01683 1.1e-225 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IICANBEH_01684 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IICANBEH_01685 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IICANBEH_01686 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IICANBEH_01687 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IICANBEH_01688 2e-131 yxkH G deacetylase
IICANBEH_01689 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IICANBEH_01690 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IICANBEH_01691 6.1e-152 rarD S Transporter
IICANBEH_01692 2.6e-16 T peptidase
IICANBEH_01693 8.9e-14 coiA 3.6.4.12 S Competence protein
IICANBEH_01694 1.1e-89 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IICANBEH_01695 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IICANBEH_01696 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IICANBEH_01697 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IICANBEH_01698 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
IICANBEH_01699 3.3e-78 atpF C ATP synthase F(0) sector subunit b
IICANBEH_01700 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IICANBEH_01701 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IICANBEH_01702 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IICANBEH_01703 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IICANBEH_01704 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IICANBEH_01705 2.8e-230 ftsW D Belongs to the SEDS family
IICANBEH_01706 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IICANBEH_01707 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IICANBEH_01708 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IICANBEH_01709 5.4e-161 holB 2.7.7.7 L dna polymerase iii
IICANBEH_01710 1.2e-133 yaaT S stage 0 sporulation protein
IICANBEH_01711 9.5e-55 yabA L Involved in initiation control of chromosome replication
IICANBEH_01712 3e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IICANBEH_01713 5.8e-225 amt P Ammonium Transporter
IICANBEH_01714 1.8e-51 glnB K Belongs to the P(II) protein family
IICANBEH_01715 2.1e-104 mur1 NU mannosyl-glycoprotein
IICANBEH_01716 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
IICANBEH_01717 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
IICANBEH_01718 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IICANBEH_01719 1.8e-53
IICANBEH_01720 7.5e-26
IICANBEH_01721 5.1e-60
IICANBEH_01722 6.1e-63 S membrane
IICANBEH_01723 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IICANBEH_01724 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IICANBEH_01725 4.5e-39 ynzC S UPF0291 protein
IICANBEH_01726 1.8e-254 cycA E permease
IICANBEH_01727 3.2e-09 uvrX 2.7.7.7 L impB/mucB/samB family
IICANBEH_01728 5.8e-71 pts33BCA G pts system
IICANBEH_01729 1.1e-76 pts33BCA G pts system
IICANBEH_01730 5.5e-84 pts33BCA G pts system
IICANBEH_01731 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IICANBEH_01736 1.4e-167 fhuR K transcriptional regulator (lysR family)
IICANBEH_01737 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IICANBEH_01738 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IICANBEH_01739 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IICANBEH_01740 4.9e-227 pyrP F uracil Permease
IICANBEH_01741 2.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IICANBEH_01742 6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
IICANBEH_01743 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
IICANBEH_01744 4.6e-132 2.1.1.223 S Putative SAM-dependent methyltransferase
IICANBEH_01745 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IICANBEH_01746 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IICANBEH_01747 3.6e-35 V efflux transmembrane transporter activity
IICANBEH_01748 1.7e-29 V efflux transmembrane transporter activity
IICANBEH_01749 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IICANBEH_01750 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IICANBEH_01751 9.1e-110 L Transposase
IICANBEH_01752 8.3e-112 L Transposase
IICANBEH_01753 1.6e-18 L Integrase core domain
IICANBEH_01756 3e-92 S MucBP domain
IICANBEH_01757 1.9e-49 M YSIRK type signal peptide
IICANBEH_01758 4.3e-143 M the current gene model (or a revised gene model) may contain a
IICANBEH_01759 0.0 mdlB V abc transporter atp-binding protein
IICANBEH_01760 0.0 lmrA V abc transporter atp-binding protein
IICANBEH_01761 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IICANBEH_01762 1.3e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IICANBEH_01763 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
IICANBEH_01764 2.5e-132 rr02 KT response regulator
IICANBEH_01765 4.1e-81 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IICANBEH_01766 9e-62 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IICANBEH_01767 2.1e-34 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IICANBEH_01768 4.8e-168 V ABC transporter
IICANBEH_01769 5.4e-122 sagI S ABC-2 type transporter
IICANBEH_01770 6.9e-197 yceA S Belongs to the UPF0176 family
IICANBEH_01771 1.6e-28 XK27_00085 K Transcriptional
IICANBEH_01772 7.3e-22
IICANBEH_01773 5.3e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
IICANBEH_01774 2.5e-113 S VIT family
IICANBEH_01775 1.1e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IICANBEH_01776 1.5e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IICANBEH_01777 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
IICANBEH_01778 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IICANBEH_01779 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IICANBEH_01780 2.3e-104 GBS0088 J protein conserved in bacteria
IICANBEH_01781 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IICANBEH_01782 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IICANBEH_01783 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
IICANBEH_01784 8.6e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IICANBEH_01785 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IICANBEH_01786 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
IICANBEH_01787 2.5e-21
IICANBEH_01788 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IICANBEH_01790 3.5e-07 U protein secretion
IICANBEH_01791 2.3e-49 U protein secretion
IICANBEH_01792 1.9e-11 U protein secretion
IICANBEH_01793 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
IICANBEH_01794 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IICANBEH_01795 4.9e-21 XK27_13030
IICANBEH_01796 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IICANBEH_01797 8.9e-57 S hydrolase activity, acting on ester bonds
IICANBEH_01798 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IICANBEH_01799 1.2e-163 S Protein of unknown function (DUF3114)
IICANBEH_01800 7.9e-22 S Protein of unknown function (DUF3114)
IICANBEH_01801 8.3e-117 yqfA K protein, Hemolysin III
IICANBEH_01802 1e-25 K hmm pf08876
IICANBEH_01803 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IICANBEH_01804 1.7e-218 mvaS 2.3.3.10 I synthase
IICANBEH_01805 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IICANBEH_01806 2.2e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IICANBEH_01807 9.7e-22
IICANBEH_01808 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IICANBEH_01809 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IICANBEH_01810 1.5e-250 mmuP E amino acid
IICANBEH_01811 5.9e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
IICANBEH_01812 1.4e-29 S Domain of unknown function (DUF1912)
IICANBEH_01813 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
IICANBEH_01814 2.3e-100 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IICANBEH_01815 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IICANBEH_01816 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IICANBEH_01817 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
IICANBEH_01818 1.1e-15 S Protein of unknown function (DUF2969)
IICANBEH_01821 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
IICANBEH_01824 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
IICANBEH_01825 6.1e-70 M Pfam SNARE associated Golgi protein
IICANBEH_01826 9.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
IICANBEH_01827 3e-51 S oxidoreductase
IICANBEH_01828 1.2e-65 S oxidoreductase
IICANBEH_01829 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
IICANBEH_01830 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IICANBEH_01831 0.0 clpE O Belongs to the ClpA ClpB family
IICANBEH_01832 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IICANBEH_01833 1.3e-34 ykuJ S protein conserved in bacteria
IICANBEH_01834 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
IICANBEH_01835 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
IICANBEH_01836 3.1e-78 feoA P FeoA domain protein
IICANBEH_01837 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IICANBEH_01838 1.5e-07
IICANBEH_01839 1.5e-35 yugF I carboxylic ester hydrolase activity
IICANBEH_01840 7.5e-23 I Alpha/beta hydrolase family
IICANBEH_01841 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IICANBEH_01842 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IICANBEH_01843 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
IICANBEH_01844 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IICANBEH_01845 1.7e-63 licT K transcriptional antiterminator
IICANBEH_01846 6.8e-53 licT K transcriptional antiterminator
IICANBEH_01847 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IICANBEH_01848 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IICANBEH_01849 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IICANBEH_01850 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IICANBEH_01851 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IICANBEH_01852 2.9e-221 mdtG EGP Major facilitator Superfamily
IICANBEH_01853 2e-33 secG U Preprotein translocase subunit SecG
IICANBEH_01854 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IICANBEH_01855 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IICANBEH_01856 3.7e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IICANBEH_01857 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
IICANBEH_01858 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
IICANBEH_01859 4.4e-183 ccpA K Catabolite control protein A
IICANBEH_01860 2.8e-28 yyaQ S YjbR
IICANBEH_01861 6.6e-101 yyaQ V Protein conserved in bacteria
IICANBEH_01862 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IICANBEH_01863 1e-78 yueI S Protein of unknown function (DUF1694)
IICANBEH_01864 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IICANBEH_01865 2e-25 WQ51_00785
IICANBEH_01866 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IICANBEH_01867 2e-219 ywbD 2.1.1.191 J Methyltransferase
IICANBEH_01868 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IICANBEH_01869 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IICANBEH_01870 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IICANBEH_01871 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IICANBEH_01872 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IICANBEH_01873 3.2e-53 yheA S Belongs to the UPF0342 family
IICANBEH_01874 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IICANBEH_01875 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IICANBEH_01876 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IICANBEH_01877 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
IICANBEH_01878 1.4e-238 msrR K Transcriptional regulator
IICANBEH_01879 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
IICANBEH_01880 2.4e-203 I acyl-CoA dehydrogenase
IICANBEH_01881 4.5e-97 mip S hydroperoxide reductase activity
IICANBEH_01882 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IICANBEH_01883 8.9e-20
IICANBEH_01884 3.2e-46
IICANBEH_01885 1e-31 K Cro/C1-type HTH DNA-binding domain
IICANBEH_01886 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
IICANBEH_01887 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
IICANBEH_01888 2.6e-93
IICANBEH_01889 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IICANBEH_01890 7.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IICANBEH_01891 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IICANBEH_01892 5.7e-189 S CRISPR-associated protein Csn2 subfamily St
IICANBEH_01893 2.4e-147 ycgQ S TIGR03943 family
IICANBEH_01894 1.5e-34 XK27_03015 S permease
IICANBEH_01895 3.4e-104 XK27_03015 S permease
IICANBEH_01897 0.0 yhgF K Transcriptional accessory protein
IICANBEH_01898 9.9e-42 pspC KT PspC domain
IICANBEH_01899 2.3e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IICANBEH_01900 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IICANBEH_01902 5.5e-69 ytxH S General stress protein
IICANBEH_01904 2.6e-177 yegQ O Peptidase U32
IICANBEH_01905 3.4e-252 yegQ O Peptidase U32
IICANBEH_01906 8.1e-46 S CHY zinc finger
IICANBEH_01907 8.4e-88 bioY S biotin synthase
IICANBEH_01909 5.2e-33 XK27_12190 S protein conserved in bacteria
IICANBEH_01910 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
IICANBEH_01911 1.3e-11
IICANBEH_01912 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
IICANBEH_01913 0.0 L helicase
IICANBEH_01914 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IICANBEH_01915 1e-163 M LysM domain
IICANBEH_01916 7.6e-16
IICANBEH_01917 2.3e-175 S hydrolase
IICANBEH_01918 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
IICANBEH_01919 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IICANBEH_01920 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
IICANBEH_01921 2.7e-27 P Hemerythrin HHE cation binding domain protein
IICANBEH_01922 2.3e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IICANBEH_01923 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
IICANBEH_01924 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
IICANBEH_01925 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
IICANBEH_01926 6.6e-290 hsdM 2.1.1.72 V N-6 DNA Methylase
IICANBEH_01927 2.2e-147 3.1.21.3 V type I restriction modification DNA specificity domain
IICANBEH_01929 2.5e-44
IICANBEH_01930 3e-38
IICANBEH_01931 3e-171 spd F DNA RNA non-specific endonuclease
IICANBEH_01932 1.7e-91 lemA S LemA family
IICANBEH_01933 2.3e-130 htpX O Belongs to the peptidase M48B family
IICANBEH_01934 1.8e-73 S Psort location CytoplasmicMembrane, score
IICANBEH_01935 6.2e-56 S Domain of unknown function (DUF4430)
IICANBEH_01936 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IICANBEH_01937 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
IICANBEH_01938 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)