ORF_ID e_value Gene_name EC_number CAZy COGs Description
JPBFLGME_00012 5.3e-11
JPBFLGME_00018 3.6e-138 mreC M Involved in formation and maintenance of cell shape
JPBFLGME_00019 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JPBFLGME_00020 4.1e-99 usp 3.5.1.28 CBM50 S CHAP domain
JPBFLGME_00021 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JPBFLGME_00022 2.5e-26
JPBFLGME_00023 8.5e-218 araT 2.6.1.1 E Aminotransferase
JPBFLGME_00024 1e-142 recO L Involved in DNA repair and RecF pathway recombination
JPBFLGME_00025 5.1e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JPBFLGME_00026 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JPBFLGME_00027 4.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JPBFLGME_00028 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JPBFLGME_00029 8.6e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JPBFLGME_00030 3.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JPBFLGME_00031 5.2e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JPBFLGME_00032 1.4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JPBFLGME_00033 3.7e-232 amt P Ammonium Transporter
JPBFLGME_00034 1.2e-52 glnB K Belongs to the P(II) protein family
JPBFLGME_00035 1.3e-103 mur1 NU mannosyl-glycoprotein
JPBFLGME_00036 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
JPBFLGME_00037 1.2e-92 nptA P COG1283 Na phosphate symporter
JPBFLGME_00038 8e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JPBFLGME_00039 2.5e-50
JPBFLGME_00040 2.2e-25
JPBFLGME_00041 8.7e-60
JPBFLGME_00042 5.2e-62 S membrane
JPBFLGME_00043 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JPBFLGME_00044 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JPBFLGME_00045 4.5e-39 ynzC S UPF0291 protein
JPBFLGME_00046 2.6e-250 cycA E permease
JPBFLGME_00047 1.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
JPBFLGME_00048 7.4e-25 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JPBFLGME_00049 6.8e-119 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
JPBFLGME_00050 1.3e-53 pts33BCA G pts system
JPBFLGME_00051 4.1e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JPBFLGME_00056 1.5e-166 fhuR K transcriptional regulator (lysR family)
JPBFLGME_00057 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JPBFLGME_00058 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JPBFLGME_00059 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JPBFLGME_00060 1.9e-226 pyrP F uracil Permease
JPBFLGME_00061 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JPBFLGME_00062 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
JPBFLGME_00063 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
JPBFLGME_00064 2.5e-122 2.1.1.223 S Putative SAM-dependent methyltransferase
JPBFLGME_00065 4.2e-175 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JPBFLGME_00066 3.7e-120 macB V ABC transporter, ATP-binding protein
JPBFLGME_00067 7.1e-212 V permease protein
JPBFLGME_00068 0.0 L SNF2 family N-terminal domain
JPBFLGME_00069 1.4e-71 S Domain of unknown function (DUF4391)
JPBFLGME_00071 0.0 res 3.1.21.5 L restriction endonuclease
JPBFLGME_00072 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JPBFLGME_00073 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JPBFLGME_00074 7.9e-64 L Transposase
JPBFLGME_00075 1.2e-112 L Transposase
JPBFLGME_00076 8.5e-22 L Transposase for ISSha1
JPBFLGME_00077 2.9e-48 U response to pH
JPBFLGME_00078 6.5e-108 L Transposase
JPBFLGME_00079 1.2e-112 L Transposase
JPBFLGME_00080 1.6e-18 L Integrase core domain
JPBFLGME_00081 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
JPBFLGME_00082 2.8e-164 hrtB V MacB-like periplasmic core domain
JPBFLGME_00085 3e-92 S MucBP domain
JPBFLGME_00086 1.9e-49 M YSIRK type signal peptide
JPBFLGME_00087 1.6e-07 S Type-A lantibiotic
JPBFLGME_00088 1.6e-07 S Type-A lantibiotic
JPBFLGME_00090 0.0 lcnDR2 V Domain of unknown function (DUF4135)
JPBFLGME_00091 0.0 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPBFLGME_00092 2e-166 bcrA V abc transporter atp-binding protein
JPBFLGME_00093 1.6e-129 S ABC-2 family transporter protein
JPBFLGME_00094 1.7e-123 S ABC-2 family transporter protein
JPBFLGME_00095 1.3e-34 K transcriptional
JPBFLGME_00096 0.0 L Recombinase zinc beta ribbon domain
JPBFLGME_00097 6e-55 J Acetyltransferase (GNAT) domain
JPBFLGME_00098 5.7e-95
JPBFLGME_00099 4.8e-142 M the current gene model (or a revised gene model) may contain a
JPBFLGME_00101 0.0 mdlB V abc transporter atp-binding protein
JPBFLGME_00102 0.0 lmrA V abc transporter atp-binding protein
JPBFLGME_00103 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JPBFLGME_00104 2.9e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JPBFLGME_00105 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
JPBFLGME_00106 2.1e-131 rr02 KT response regulator
JPBFLGME_00107 9.7e-83 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JPBFLGME_00108 1.7e-107 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JPBFLGME_00109 5.3e-167 V ABC transporter
JPBFLGME_00110 5.4e-122 sagI S ABC-2 type transporter
JPBFLGME_00111 6.5e-195 yceA S Belongs to the UPF0176 family
JPBFLGME_00112 1.6e-28 XK27_00085 K Transcriptional
JPBFLGME_00113 7.4e-22
JPBFLGME_00114 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
JPBFLGME_00115 5.6e-113 S VIT family
JPBFLGME_00116 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JPBFLGME_00117 1.5e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JPBFLGME_00118 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
JPBFLGME_00119 3.8e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
JPBFLGME_00120 2.2e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JPBFLGME_00121 8.8e-104 GBS0088 J protein conserved in bacteria
JPBFLGME_00122 1.6e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JPBFLGME_00123 1.1e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JPBFLGME_00124 3.1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
JPBFLGME_00125 6.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JPBFLGME_00126 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JPBFLGME_00127 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
JPBFLGME_00128 2.5e-21
JPBFLGME_00129 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JPBFLGME_00131 3e-29 U protein secretion
JPBFLGME_00132 1.8e-49 U protein secretion
JPBFLGME_00133 2.5e-08 M Pilin isopeptide linkage domain protein
JPBFLGME_00134 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
JPBFLGME_00135 3.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JPBFLGME_00136 3.5e-49 XK27_13030
JPBFLGME_00137 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JPBFLGME_00138 2.2e-168 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JPBFLGME_00139 9.8e-163 S Protein of unknown function (DUF3114)
JPBFLGME_00140 1.2e-22 S Protein of unknown function (DUF3114)
JPBFLGME_00141 4.7e-120 yqfA K protein, Hemolysin III
JPBFLGME_00142 1.6e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JPBFLGME_00143 2.9e-218 mvaS 2.3.3.10 I synthase
JPBFLGME_00144 1.9e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JPBFLGME_00145 5.3e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JPBFLGME_00146 9.7e-22
JPBFLGME_00147 3.7e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JPBFLGME_00148 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
JPBFLGME_00149 1.3e-249 mmuP E amino acid
JPBFLGME_00150 3.1e-178 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
JPBFLGME_00151 1.4e-29 S Domain of unknown function (DUF1912)
JPBFLGME_00152 8.3e-15 L Helix-hairpin-helix DNA-binding motif class 1
JPBFLGME_00153 1.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JPBFLGME_00154 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JPBFLGME_00155 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JPBFLGME_00156 3.4e-199 ilvE 2.6.1.42 E Aminotransferase
JPBFLGME_00157 1.1e-15 S Protein of unknown function (DUF2969)
JPBFLGME_00160 1.3e-202 rpsA 1.17.7.4 J ribosomal protein S1
JPBFLGME_00163 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
JPBFLGME_00164 6.1e-70 M Pfam SNARE associated Golgi protein
JPBFLGME_00165 9.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
JPBFLGME_00166 3e-51 S oxidoreductase
JPBFLGME_00167 1.4e-54 S oxidoreductase
JPBFLGME_00168 2.4e-47 XK27_09445 S Domain of unknown function (DUF1827)
JPBFLGME_00169 5.7e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JPBFLGME_00170 0.0 clpE O Belongs to the ClpA ClpB family
JPBFLGME_00171 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JPBFLGME_00172 1.3e-34 ykuJ S protein conserved in bacteria
JPBFLGME_00173 3.2e-116 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
JPBFLGME_00174 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPBFLGME_00175 1.2e-77 feoA P FeoA domain protein
JPBFLGME_00176 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
JPBFLGME_00177 1.5e-07
JPBFLGME_00178 1.9e-33 yugF I carboxylic ester hydrolase activity
JPBFLGME_00179 1.5e-23 I Alpha/beta hydrolase family
JPBFLGME_00180 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JPBFLGME_00181 1.7e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JPBFLGME_00182 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
JPBFLGME_00183 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JPBFLGME_00185 3.6e-77 licT K antiterminator
JPBFLGME_00186 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JPBFLGME_00187 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JPBFLGME_00188 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JPBFLGME_00189 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JPBFLGME_00190 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JPBFLGME_00191 1.6e-219 mdtG EGP Major facilitator Superfamily
JPBFLGME_00192 2.6e-33 secG U Preprotein translocase subunit SecG
JPBFLGME_00193 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JPBFLGME_00194 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JPBFLGME_00195 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JPBFLGME_00196 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
JPBFLGME_00197 2.7e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
JPBFLGME_00198 3.7e-182 ccpA K Catabolite control protein A
JPBFLGME_00199 5.2e-27 yyaQ S YjbR
JPBFLGME_00200 2.9e-111 yyaQ S YjbR
JPBFLGME_00201 2.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JPBFLGME_00202 5.7e-77 yueI S Protein of unknown function (DUF1694)
JPBFLGME_00203 8.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JPBFLGME_00204 4.6e-208 S Phage integrase family
JPBFLGME_00205 1.7e-22 S Host cell surface-exposed lipoprotein
JPBFLGME_00206 2.3e-20 E Zn peptidase
JPBFLGME_00207 3.7e-52 S sequence-specific DNA binding
JPBFLGME_00208 2.4e-28 S sequence-specific DNA binding
JPBFLGME_00209 5.1e-138
JPBFLGME_00210 3.5e-09 S ORF6C domain
JPBFLGME_00212 1.1e-118 S Replication initiator protein A (RepA) N-terminus
JPBFLGME_00213 3.8e-129 S IstB-like ATP binding protein
JPBFLGME_00215 8.8e-69 S DNA metabolic process
JPBFLGME_00216 7.9e-52 S Protein of unknown function (DUF1351)
JPBFLGME_00217 3.6e-68 S Single-strand binding protein family
JPBFLGME_00218 9.8e-77 S magnesium ion binding
JPBFLGME_00222 7.5e-34 S Protein of unknown function (DUF1642)
JPBFLGME_00223 4.9e-142 S N-methyltransferase activity
JPBFLGME_00224 4.6e-29 S Protein of unknown function (DUF1642)
JPBFLGME_00225 7.4e-73 S sequence-specific DNA binding
JPBFLGME_00226 3.2e-07 S Protein of unknown function (DUF1372)
JPBFLGME_00227 3.9e-58
JPBFLGME_00229 1.1e-31
JPBFLGME_00230 1.2e-23 L DNA packaging
JPBFLGME_00231 5.2e-234 S Terminase-like family
JPBFLGME_00232 5.9e-272 S Phage portal protein, SPP1 Gp6-like
JPBFLGME_00233 1.6e-144 S Phage Mu protein F like protein
JPBFLGME_00234 5.6e-21 S Domain of unknown function (DUF4355)
JPBFLGME_00235 1.2e-16
JPBFLGME_00236 2.8e-188 S Phage major capsid protein E
JPBFLGME_00238 4.7e-36 S Phage gp6-like head-tail connector protein
JPBFLGME_00240 2e-42 S exonuclease activity
JPBFLGME_00241 7.7e-67
JPBFLGME_00242 2.7e-88 S Phage major tail protein 2
JPBFLGME_00243 1e-57 S Pfam:Phage_TAC_12
JPBFLGME_00245 2.1e-264 S peptidoglycan catabolic process
JPBFLGME_00246 5e-170 S Phage tail protein
JPBFLGME_00247 0.0 S peptidoglycan catabolic process
JPBFLGME_00248 0.0 S N-acetylmuramoyl-L-alanine amidase activity
JPBFLGME_00251 5.4e-45 S Pfam:Phage_holin_4_1
JPBFLGME_00252 1.1e-21 S COG5546 Small integral membrane protein
JPBFLGME_00253 3.6e-109 M Bacteriophage peptidoglycan hydrolase
JPBFLGME_00259 1.3e-24 WQ51_00785
JPBFLGME_00260 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JPBFLGME_00261 2.6e-219 ywbD 2.1.1.191 J Methyltransferase
JPBFLGME_00262 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JPBFLGME_00263 1.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JPBFLGME_00264 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JPBFLGME_00265 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JPBFLGME_00266 6.3e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JPBFLGME_00267 3.2e-53 yheA S Belongs to the UPF0342 family
JPBFLGME_00268 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
JPBFLGME_00269 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JPBFLGME_00270 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JPBFLGME_00271 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
JPBFLGME_00272 9e-238 msrR K Transcriptional regulator
JPBFLGME_00273 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
JPBFLGME_00274 7e-203 I acyl-CoA dehydrogenase
JPBFLGME_00275 4.5e-97 mip S hydroperoxide reductase activity
JPBFLGME_00276 1.8e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JPBFLGME_00277 1.1e-20
JPBFLGME_00278 1.9e-139 repA S Replication initiator protein A (RepA) N-terminus
JPBFLGME_00279 2.5e-203 hpaIIM 2.1.1.37 H cytosine-specific methyltransferase
JPBFLGME_00280 6.5e-75 XK27_00590
JPBFLGME_00281 1.2e-64 XK27_00585 P arsenate reductase (glutaredoxin) activity
JPBFLGME_00282 1.5e-36 XK27_00580
JPBFLGME_00283 8.3e-89 ypbD S CAAX protease self-immunity
JPBFLGME_00284 9.3e-78 XK27_00570
JPBFLGME_00285 0.0 traG U Type IV secretory system Conjugative DNA transfer
JPBFLGME_00286 4.6e-33 XK27_00560
JPBFLGME_00287 9.7e-139
JPBFLGME_00288 7.5e-61 XK27_00550 S PrgI family protein
JPBFLGME_00289 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
JPBFLGME_00290 0.0 XK27_00530 S CHAP domain
JPBFLGME_00291 4.4e-48 V Abi-like protein
JPBFLGME_00292 1.1e-94 V Abi-like protein
JPBFLGME_00293 0.0 XK27_00515 D Glucan-binding protein C
JPBFLGME_00294 5.1e-11 XK27_00510
JPBFLGME_00295 1.6e-89 XK27_00505
JPBFLGME_00296 0.0 XK27_00500 L SNF2 family N-terminal domain
JPBFLGME_00297 6e-43
JPBFLGME_00298 2.4e-36
JPBFLGME_00299 7.1e-102 XK27_10865
JPBFLGME_00300 3.8e-188 L Toprim-like
JPBFLGME_00301 2.5e-17 XK27_10875
JPBFLGME_00302 1.5e-57 XK27_10880
JPBFLGME_00303 1.5e-30
JPBFLGME_00304 1.6e-82 nprA K Cro/C1-type HTH DNA-binding domain
JPBFLGME_00305 2.3e-131 2.7.1.176 O Zeta toxin
JPBFLGME_00306 0.0 L ATP-dependent endonuclease of the OLD family
JPBFLGME_00307 1.3e-302 L Superfamily I DNA and RNA helicases
JPBFLGME_00308 1.1e-220 K Putative DNA-binding domain
JPBFLGME_00309 1.5e-56
JPBFLGME_00310 1.1e-57 S Bacterial mobilisation protein (MobC)
JPBFLGME_00311 0.0 U relaxase
JPBFLGME_00312 9.7e-250 T PhoQ Sensor
JPBFLGME_00313 1.1e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPBFLGME_00314 8.9e-11
JPBFLGME_00315 7.8e-59 S Protein of unknown function (DUF1722)
JPBFLGME_00316 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
JPBFLGME_00318 2.4e-33
JPBFLGME_00319 1.7e-26 S CAAX protease self-immunity
JPBFLGME_00320 1e-30 S CAAX protease self-immunity
JPBFLGME_00321 1.9e-27 estA E GDSL-like Lipase/Acylhydrolase
JPBFLGME_00322 2.1e-95
JPBFLGME_00323 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
JPBFLGME_00324 5.5e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JPBFLGME_00325 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JPBFLGME_00326 5.9e-186 S CRISPR-associated protein Csn2 subfamily St
JPBFLGME_00327 3.5e-146 ycgQ S TIGR03943 family
JPBFLGME_00328 1.6e-155 XK27_03015 S permease
JPBFLGME_00330 0.0 yhgF K Transcriptional accessory protein
JPBFLGME_00331 6.4e-41 pspC KT PspC domain
JPBFLGME_00332 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JPBFLGME_00333 3.1e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JPBFLGME_00335 1.2e-68 ytxH S General stress protein
JPBFLGME_00337 1.7e-176 yegQ O Peptidase U32
JPBFLGME_00338 3.4e-252 yegQ O Peptidase U32
JPBFLGME_00339 2.1e-86 bioY S biotin synthase
JPBFLGME_00341 1.1e-33 XK27_12190 S protein conserved in bacteria
JPBFLGME_00342 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
JPBFLGME_00344 3.7e-114 L Transposase
JPBFLGME_00345 3.5e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JPBFLGME_00346 1.9e-15 M LysM domain
JPBFLGME_00347 2.4e-58 M LysM domain
JPBFLGME_00348 3.5e-19
JPBFLGME_00349 6.4e-173 S hydrolase
JPBFLGME_00350 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
JPBFLGME_00351 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JPBFLGME_00352 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
JPBFLGME_00353 2.7e-27 P Hemerythrin HHE cation binding domain protein
JPBFLGME_00354 2.6e-112 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JPBFLGME_00355 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
JPBFLGME_00356 2.2e-48 MA20_36090 S Protein of unknown function (DUF2974)
JPBFLGME_00357 7.4e-130 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JPBFLGME_00358 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
JPBFLGME_00359 9.2e-53
JPBFLGME_00361 1.3e-17
JPBFLGME_00362 1e-120 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
JPBFLGME_00363 0.0 S KAP family P-loop domain
JPBFLGME_00364 5.6e-130 S Protein conserved in bacteria
JPBFLGME_00365 4.3e-305 hsdM 2.1.1.72 V type I restriction-modification system
JPBFLGME_00366 2.3e-48 S double-stranded DNA endodeoxyribonuclease activity
JPBFLGME_00367 1.7e-171 spd F DNA RNA non-specific endonuclease
JPBFLGME_00368 2.6e-92 lemA S LemA family
JPBFLGME_00369 6.4e-133 htpX O Belongs to the peptidase M48B family
JPBFLGME_00370 4.2e-75 S Psort location CytoplasmicMembrane, score
JPBFLGME_00371 6.2e-56 S Domain of unknown function (DUF4430)
JPBFLGME_00372 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JPBFLGME_00373 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
JPBFLGME_00374 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
JPBFLGME_00375 3e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
JPBFLGME_00376 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
JPBFLGME_00377 3.2e-92 dps P Belongs to the Dps family
JPBFLGME_00378 4.4e-79 perR P Belongs to the Fur family
JPBFLGME_00379 1.9e-27 yqgQ S protein conserved in bacteria
JPBFLGME_00380 7.8e-177 glk 2.7.1.2 G Glucokinase
JPBFLGME_00381 0.0 typA T GTP-binding protein TypA
JPBFLGME_00383 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JPBFLGME_00384 3.9e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JPBFLGME_00385 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JPBFLGME_00386 1.2e-250 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JPBFLGME_00387 2.7e-236 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JPBFLGME_00388 5.1e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JPBFLGME_00389 1.4e-96 sepF D cell septum assembly
JPBFLGME_00390 9.7e-34 yggT D integral membrane protein
JPBFLGME_00391 8e-143 ylmH T S4 RNA-binding domain
JPBFLGME_00392 9.7e-134 divIVA D Cell division protein DivIVA
JPBFLGME_00393 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JPBFLGME_00394 7.9e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
JPBFLGME_00395 2e-45 rpmE2 J 50S ribosomal protein L31
JPBFLGME_00396 1.2e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
JPBFLGME_00397 7.6e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
JPBFLGME_00398 2.6e-154 gst O Glutathione S-transferase
JPBFLGME_00399 6.7e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JPBFLGME_00400 3.5e-111 tdk 2.7.1.21 F thymidine kinase
JPBFLGME_00401 1.8e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JPBFLGME_00402 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JPBFLGME_00403 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JPBFLGME_00404 3.4e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JPBFLGME_00405 1.3e-174 ndpA S 37-kD nucleoid-associated bacterial protein
JPBFLGME_00406 8e-100 pvaA M lytic transglycosylase activity
JPBFLGME_00407 1.2e-305 yfiB1 V abc transporter atp-binding protein
JPBFLGME_00408 9.7e-311 XK27_10035 V abc transporter atp-binding protein
JPBFLGME_00409 1.3e-09 S D-Ala-teichoic acid biosynthesis protein
JPBFLGME_00410 6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPBFLGME_00411 1.6e-235 dltB M Membrane protein involved in D-alanine export
JPBFLGME_00412 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPBFLGME_00413 4.4e-228 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JPBFLGME_00414 4.9e-57 L Integrase core domain protein
JPBFLGME_00415 3.7e-18 L transposase activity
JPBFLGME_00416 3.6e-39 L Transposase
JPBFLGME_00417 0.0 3.6.3.8 P cation transport ATPase
JPBFLGME_00418 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
JPBFLGME_00420 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JPBFLGME_00421 2.1e-165 metF 1.5.1.20 C reductase
JPBFLGME_00422 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JPBFLGME_00423 1.1e-93 panT S ECF transporter, substrate-specific component
JPBFLGME_00424 2.8e-91 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JPBFLGME_00425 2.8e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
JPBFLGME_00426 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JPBFLGME_00427 1.2e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPBFLGME_00428 4.1e-43 T PhoQ Sensor
JPBFLGME_00429 1.7e-120 T PhoQ Sensor
JPBFLGME_00430 1.2e-21 L Transposase
JPBFLGME_00437 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JPBFLGME_00438 2.1e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JPBFLGME_00439 1.6e-35 XK27_02060 S Transglycosylase associated protein
JPBFLGME_00440 1.3e-54 badR K DNA-binding transcription factor activity
JPBFLGME_00441 3.5e-97 S reductase
JPBFLGME_00442 1.2e-32 L Integrase core domain protein
JPBFLGME_00444 7.5e-172 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JPBFLGME_00446 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
JPBFLGME_00447 6.6e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JPBFLGME_00448 9.3e-83 S Putative small multi-drug export protein
JPBFLGME_00449 6.2e-76 ctsR K Belongs to the CtsR family
JPBFLGME_00450 0.0 clpC O Belongs to the ClpA ClpB family
JPBFLGME_00451 2.1e-30 rpsT J rRNA binding
JPBFLGME_00452 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
JPBFLGME_00453 3.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
JPBFLGME_00454 9.3e-35 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JPBFLGME_00455 3e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
JPBFLGME_00456 7.1e-59 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
JPBFLGME_00457 2.3e-43 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
JPBFLGME_00458 3.2e-38 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JPBFLGME_00459 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JPBFLGME_00460 5.8e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JPBFLGME_00461 5.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JPBFLGME_00462 8.9e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
JPBFLGME_00463 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
JPBFLGME_00464 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JPBFLGME_00465 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JPBFLGME_00466 3.1e-81 ypmB S Protein conserved in bacteria
JPBFLGME_00467 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JPBFLGME_00468 3.5e-260 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JPBFLGME_00469 3.7e-19
JPBFLGME_00470 3.3e-201 pmrB EGP Major facilitator Superfamily
JPBFLGME_00471 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
JPBFLGME_00472 2.2e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JPBFLGME_00473 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
JPBFLGME_00474 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JPBFLGME_00475 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
JPBFLGME_00476 3.6e-17 D nuclear chromosome segregation
JPBFLGME_00477 8.5e-134 yejC S cyclic nucleotide-binding protein
JPBFLGME_00478 4.5e-163 rapZ S Displays ATPase and GTPase activities
JPBFLGME_00479 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JPBFLGME_00480 1.9e-161 whiA K May be required for sporulation
JPBFLGME_00481 7.2e-25 pepD E Dipeptidase
JPBFLGME_00482 5.8e-77 pepD E Dipeptidase
JPBFLGME_00483 2.6e-44 pepD E Dipeptidase
JPBFLGME_00484 9.9e-64 tnp L DDE domain
JPBFLGME_00485 7.1e-28 L transposase activity
JPBFLGME_00487 2.4e-27
JPBFLGME_00488 9.3e-32 cspD K Cold shock protein domain
JPBFLGME_00489 8e-42 K Cold-Shock Protein
JPBFLGME_00490 3.2e-89 L Transposase
JPBFLGME_00491 0.0 copB 3.6.3.4 P COG2217 Cation transport ATPase
JPBFLGME_00494 3.9e-17 L Psort location Cytoplasmic, score
JPBFLGME_00495 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
JPBFLGME_00500 4.1e-111 glcU U sugar transport
JPBFLGME_00501 2.3e-93 hsdM 2.1.1.72 V type I restriction-modification system
JPBFLGME_00502 7.4e-55 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
JPBFLGME_00503 1.5e-147
JPBFLGME_00504 5.6e-101 L Phage integrase family
JPBFLGME_00505 8e-102
JPBFLGME_00507 2.4e-57 pepD E Dipeptidase
JPBFLGME_00508 6.4e-58 XK27_10720 D peptidase activity
JPBFLGME_00509 6.2e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
JPBFLGME_00510 1.7e-08
JPBFLGME_00511 1.5e-170 yeiH S Membrane
JPBFLGME_00512 1.6e-118 mur1 NU muramidase
JPBFLGME_00513 4.2e-20 L transposase activity
JPBFLGME_00514 2.2e-165 cpsY K Transcriptional regulator
JPBFLGME_00515 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JPBFLGME_00516 6.1e-57 phnA P Alkylphosphonate utilization operon protein PhnA
JPBFLGME_00517 5.3e-105 artQ P ABC transporter (Permease
JPBFLGME_00518 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPBFLGME_00519 1.2e-157 aatB ET ABC transporter substrate-binding protein
JPBFLGME_00520 2.1e-73 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPBFLGME_00521 1.1e-31 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPBFLGME_00522 1.6e-65 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPBFLGME_00523 2.1e-07
JPBFLGME_00524 5.6e-61 adhP 1.1.1.1 C alcohol dehydrogenase
JPBFLGME_00525 5.7e-110 adhP 1.1.1.1 C alcohol dehydrogenase
JPBFLGME_00527 3e-21
JPBFLGME_00528 0.0 res_1 3.1.21.5 S Type III restriction
JPBFLGME_00529 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
JPBFLGME_00530 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JPBFLGME_00531 2e-126 gntR1 K transcriptional
JPBFLGME_00532 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JPBFLGME_00533 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JPBFLGME_00534 3.1e-87 niaX
JPBFLGME_00535 3e-90 niaR S small molecule binding protein (contains 3H domain)
JPBFLGME_00536 8.1e-128 K DNA-binding helix-turn-helix protein
JPBFLGME_00537 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JPBFLGME_00538 2.6e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JPBFLGME_00539 3.5e-166 GK ROK family
JPBFLGME_00540 3.5e-157 dprA LU DNA protecting protein DprA
JPBFLGME_00541 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JPBFLGME_00542 3.6e-154 S TraX protein
JPBFLGME_00543 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPBFLGME_00544 3.4e-250 T PhoQ Sensor
JPBFLGME_00545 9.6e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JPBFLGME_00546 1.4e-77 XK27_05470 E Methionine synthase
JPBFLGME_00547 1e-34 XK27_05470 E Methionine synthase
JPBFLGME_00548 5e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JPBFLGME_00549 4.4e-45 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JPBFLGME_00550 2.9e-92 ET Bacterial periplasmic substrate-binding proteins
JPBFLGME_00551 1.8e-136 IQ Acetoin reductase
JPBFLGME_00553 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JPBFLGME_00554 2e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JPBFLGME_00557 1.1e-212 pqqE C radical SAM domain protein
JPBFLGME_00558 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
JPBFLGME_00559 6.6e-61 EGP Major facilitator Superfamily
JPBFLGME_00560 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JPBFLGME_00561 2e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
JPBFLGME_00562 2.7e-116 V ABC transporter (Permease
JPBFLGME_00563 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JPBFLGME_00564 1.6e-10
JPBFLGME_00565 1.2e-97 K Transcriptional regulator, TetR family
JPBFLGME_00566 1.8e-159 czcD P cation diffusion facilitator family transporter
JPBFLGME_00567 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JPBFLGME_00568 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JPBFLGME_00569 2.3e-195 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
JPBFLGME_00570 2.3e-07 S Hydrolases of the alpha beta superfamily
JPBFLGME_00571 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
JPBFLGME_00572 1.2e-79 S Alpha/beta hydrolase of unknown function (DUF915)
JPBFLGME_00575 1.2e-143 2.4.2.3 F Phosphorylase superfamily
JPBFLGME_00576 1.2e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
JPBFLGME_00577 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
JPBFLGME_00578 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
JPBFLGME_00579 3.9e-15 dinF V Mate efflux family protein
JPBFLGME_00581 1.1e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JPBFLGME_00583 1.8e-80 S TraX protein
JPBFLGME_00584 5e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
JPBFLGME_00585 4.8e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JPBFLGME_00586 1.9e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JPBFLGME_00587 9.1e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JPBFLGME_00588 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JPBFLGME_00589 7.1e-18 nylA 3.5.1.4 J amidase activity
JPBFLGME_00590 7.3e-85 nylA 3.5.1.4 J Belongs to the amidase family
JPBFLGME_00591 8.5e-79 yckB ET Belongs to the bacterial solute-binding protein 3 family
JPBFLGME_00592 1.1e-47 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
JPBFLGME_00593 4.1e-66 yecS P ABC transporter (Permease
JPBFLGME_00594 3.5e-21 yecS P amino acid transport
JPBFLGME_00596 2.6e-23 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
JPBFLGME_00597 1.4e-87 yfiF3 K sequence-specific DNA binding
JPBFLGME_00598 1.6e-23 bglC K Transcriptional regulator
JPBFLGME_00599 8.6e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JPBFLGME_00600 7.6e-239 agcS E (Alanine) symporter
JPBFLGME_00601 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JPBFLGME_00602 2.3e-240 metY 2.5.1.49 E o-acetylhomoserine
JPBFLGME_00603 3.2e-133 S haloacid dehalogenase-like hydrolase
JPBFLGME_00604 3.8e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JPBFLGME_00605 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
JPBFLGME_00606 3.1e-31 M1-755 P Hemerythrin HHE cation binding domain protein
JPBFLGME_00607 5.8e-78 XK27_04775 S hemerythrin HHE cation binding domain
JPBFLGME_00608 4e-32 XK27_04775 S hemerythrin HHE cation binding domain
JPBFLGME_00609 1.3e-28 XK27_04775 S hemerythrin HHE cation binding domain
JPBFLGME_00610 1.1e-34 XK27_04775 S hemerythrin HHE cation binding domain
JPBFLGME_00611 8.4e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JPBFLGME_00612 5.5e-172 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JPBFLGME_00613 1.1e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JPBFLGME_00614 6.7e-44 yktA S Belongs to the UPF0223 family
JPBFLGME_00615 4.2e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JPBFLGME_00616 3.9e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JPBFLGME_00617 4.8e-157 pstS P phosphate
JPBFLGME_00618 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
JPBFLGME_00619 1.5e-155 pstA P phosphate transport system permease
JPBFLGME_00620 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JPBFLGME_00621 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JPBFLGME_00622 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
JPBFLGME_00623 0.0 pepN 3.4.11.2 E aminopeptidase
JPBFLGME_00624 1e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
JPBFLGME_00625 1.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
JPBFLGME_00628 3.7e-09
JPBFLGME_00629 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
JPBFLGME_00630 1.7e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
JPBFLGME_00631 2.3e-23 L Transposase
JPBFLGME_00632 4.6e-25 tatA U protein secretion
JPBFLGME_00633 4.4e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JPBFLGME_00634 7.2e-303 ywbL P COG0672 High-affinity Fe2 Pb2 permease
JPBFLGME_00635 5.6e-233 ycdB P peroxidase
JPBFLGME_00636 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
JPBFLGME_00637 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPBFLGME_00638 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPBFLGME_00639 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPBFLGME_00640 2.9e-208 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPBFLGME_00641 7e-173 3.5.1.28 M GBS Bsp-like repeat
JPBFLGME_00642 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JPBFLGME_00643 9.9e-12 3.5.1.28 NU amidase activity
JPBFLGME_00644 0.0 lpdA 1.8.1.4 C Dehydrogenase
JPBFLGME_00645 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JPBFLGME_00646 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JPBFLGME_00647 8.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JPBFLGME_00648 0.0 S the current gene model (or a revised gene model) may contain a frame shift
JPBFLGME_00649 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JPBFLGME_00650 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JPBFLGME_00651 5.2e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JPBFLGME_00652 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
JPBFLGME_00653 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
JPBFLGME_00654 4.1e-127 3.4.16.4 M Belongs to the peptidase S11 family
JPBFLGME_00655 4.6e-157 rssA S Phospholipase, patatin family
JPBFLGME_00656 5.1e-38 estA E GDSL-like protein
JPBFLGME_00657 3.4e-29 estA E Lysophospholipase L1 and related esterases
JPBFLGME_00658 1.6e-291 S unusual protein kinase
JPBFLGME_00659 4.9e-39 S granule-associated protein
JPBFLGME_00660 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
JPBFLGME_00661 7.7e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPBFLGME_00662 8.4e-27 bglH 3.2.1.86 GT1 G beta-glucosidase activity
JPBFLGME_00663 1e-196 S hmm pf01594
JPBFLGME_00664 8.1e-100 G Belongs to the phosphoglycerate mutase family
JPBFLGME_00665 4.4e-33 G Belongs to the phosphoglycerate mutase family
JPBFLGME_00666 3.8e-94 V VanZ like family
JPBFLGME_00667 5.4e-23 L Transposase
JPBFLGME_00668 4.1e-195 wbbI M transferase activity, transferring glycosyl groups
JPBFLGME_00669 2.1e-57 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
JPBFLGME_00670 5.4e-68 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
JPBFLGME_00671 4.8e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
JPBFLGME_00672 4.6e-242 epsU S Polysaccharide biosynthesis protein
JPBFLGME_00673 7.1e-86 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
JPBFLGME_00675 1e-168 M Glycosyltransferase, group 2 family protein
JPBFLGME_00676 9.2e-60 ycbI M Glycosyl transferase family 2
JPBFLGME_00677 1.1e-17
JPBFLGME_00678 3.9e-96 M Glycosyltransferase sugar-binding region containing DXD motif
JPBFLGME_00679 1.4e-70 pssE S Glycosyltransferase family 28 C-terminal domain
JPBFLGME_00680 4.6e-79 cpsF M Oligosaccharide biosynthesis protein Alg14 like
JPBFLGME_00681 3.4e-83 cpsE M Bacterial sugar transferase
JPBFLGME_00682 1.2e-84 cpsE M Bacterial sugar transferase
JPBFLGME_00683 2.2e-23 rgpAc GT4 M group 1 family protein
JPBFLGME_00684 8.8e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
JPBFLGME_00685 2.4e-112 cpsD D COG0489 ATPases involved in chromosome partitioning
JPBFLGME_00686 1e-101 cps4C M biosynthesis protein
JPBFLGME_00687 1.1e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
JPBFLGME_00688 1.3e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
JPBFLGME_00689 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
JPBFLGME_00690 1.5e-124 yfeJ 6.3.5.2 F glutamine amidotransferase
JPBFLGME_00691 3.5e-56 clcA_2 P chloride
JPBFLGME_00692 1.1e-58 clcA_2 P chloride
JPBFLGME_00693 1.3e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JPBFLGME_00694 1.3e-88 S Protein of unknown function (DUF1697)
JPBFLGME_00695 1.2e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JPBFLGME_00696 1.9e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JPBFLGME_00698 5.7e-08 V Glucan-binding protein C
JPBFLGME_00699 3.6e-22 V Glucan-binding protein C
JPBFLGME_00700 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
JPBFLGME_00701 9e-275 pepV 3.5.1.18 E Dipeptidase
JPBFLGME_00702 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JPBFLGME_00703 2e-41 XK27_03610 K Gnat family
JPBFLGME_00704 7.2e-83 L Transposase
JPBFLGME_00705 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JPBFLGME_00706 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JPBFLGME_00707 5.9e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JPBFLGME_00708 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JPBFLGME_00709 2.8e-18 M LysM domain
JPBFLGME_00710 1.2e-88 ebsA S Family of unknown function (DUF5322)
JPBFLGME_00711 1.8e-139 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JPBFLGME_00712 2.4e-43 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JPBFLGME_00713 6e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JPBFLGME_00714 5.4e-223 G COG0457 FOG TPR repeat
JPBFLGME_00715 8.1e-176 yubA S permease
JPBFLGME_00716 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
JPBFLGME_00717 5.2e-162 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JPBFLGME_00718 5.5e-124 ftsE D cell division ATP-binding protein FtsE
JPBFLGME_00719 1.1e-181 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JPBFLGME_00720 7.9e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JPBFLGME_00721 1.3e-181 yjjH S Calcineurin-like phosphoesterase
JPBFLGME_00722 3.3e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
JPBFLGME_00723 0.0 pacL 3.6.3.8 P cation transport ATPase
JPBFLGME_00724 3.4e-67 ywiB S Domain of unknown function (DUF1934)
JPBFLGME_00725 2.4e-44 XK27_00115 2.3.1.128 K acetyltransferase
JPBFLGME_00726 9.2e-147 yidA S hydrolases of the HAD superfamily
JPBFLGME_00727 3.4e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
JPBFLGME_00728 4.2e-34 F Protein of unknown function (DUF454)
JPBFLGME_00729 3.9e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
JPBFLGME_00730 5.8e-247 vicK 2.7.13.3 T Histidine kinase
JPBFLGME_00731 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPBFLGME_00732 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPBFLGME_00733 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JPBFLGME_00734 1.8e-114 gltJ P ABC transporter (Permease
JPBFLGME_00735 1.2e-109 tcyB_2 P ABC transporter (permease)
JPBFLGME_00736 1.4e-145 endA F DNA RNA non-specific endonuclease
JPBFLGME_00737 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
JPBFLGME_00738 9.4e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JPBFLGME_00740 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JPBFLGME_00741 1.3e-36 5.1.3.2 GM Psort location CytoplasmicMembrane, score
JPBFLGME_00742 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JPBFLGME_00743 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JPBFLGME_00744 7.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JPBFLGME_00745 2.7e-88 ytsP 1.8.4.14 T GAF domain-containing protein
JPBFLGME_00746 3e-162 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JPBFLGME_00747 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
JPBFLGME_00749 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JPBFLGME_00750 2.1e-219 XK27_05110 P chloride
JPBFLGME_00751 2.5e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
JPBFLGME_00752 9.8e-283 clcA P Chloride transporter, ClC family
JPBFLGME_00753 1e-75 fld C Flavodoxin
JPBFLGME_00754 3.3e-14 XK27_08880
JPBFLGME_00755 6.1e-126 XK27_08875 O Zinc-dependent metalloprotease
JPBFLGME_00756 1.1e-149 estA CE1 S Putative esterase
JPBFLGME_00757 4.3e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JPBFLGME_00758 8.4e-134 XK27_08845 S abc transporter atp-binding protein
JPBFLGME_00759 1.3e-143 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
JPBFLGME_00760 5.8e-175 XK27_08835 S ABC transporter substrate binding protein
JPBFLGME_00761 3.2e-17 S Domain of unknown function (DUF4649)
JPBFLGME_00762 9e-11 Q the current gene model (or a revised gene model) may contain a frame shift
JPBFLGME_00763 9.4e-14 Q the current gene model (or a revised gene model) may contain a frame shift
JPBFLGME_00765 8.3e-10 Q the current gene model (or a revised gene model) may contain a frame shift
JPBFLGME_00766 5.6e-129 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JPBFLGME_00767 3.9e-59 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JPBFLGME_00768 7.1e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JPBFLGME_00769 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JPBFLGME_00770 2.2e-142 S SseB protein N-terminal domain
JPBFLGME_00771 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
JPBFLGME_00772 1.5e-255 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JPBFLGME_00773 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JPBFLGME_00776 2.4e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JPBFLGME_00777 4.6e-91 yacP S RNA-binding protein containing a PIN domain
JPBFLGME_00778 2.8e-154 degV S DegV family
JPBFLGME_00779 4.3e-20 K helix-turn-helix
JPBFLGME_00780 3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JPBFLGME_00781 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JPBFLGME_00782 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
JPBFLGME_00783 6.7e-210 L Phage integrase family
JPBFLGME_00784 1e-33 S Helix-turn-helix domain
JPBFLGME_00785 8.4e-97 S Plasmid replication protein
JPBFLGME_00786 2.3e-65
JPBFLGME_00787 1.2e-197 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
JPBFLGME_00788 1.9e-47
JPBFLGME_00790 4.3e-181 norB P Major Facilitator Superfamily
JPBFLGME_00791 3.8e-78 C nadph quinone reductase
JPBFLGME_00792 1.4e-37 K Transcriptional regulator
JPBFLGME_00793 1.4e-68 S phosphonoacetaldehyde hydrolase activity
JPBFLGME_00794 1.7e-28 pcaC 3.1.1.24, 4.1.1.44 S peroxiredoxin activity
JPBFLGME_00795 6.5e-31 ais G Phosphoglycerate mutase
JPBFLGME_00798 6.2e-128 tnp L Transposase IS66 family
JPBFLGME_00799 3.3e-247 G polysaccharide deacetylase
JPBFLGME_00800 5.5e-65 dhaL 2.7.1.121 G Dihydroxyacetone kinase
JPBFLGME_00801 2.9e-125 tnp L Transposase IS66 family
JPBFLGME_00802 2.8e-224 capA M Bacterial capsule synthesis protein
JPBFLGME_00803 6.1e-39 gcvR T UPF0237 protein
JPBFLGME_00804 3.9e-243 XK27_08635 S UPF0210 protein
JPBFLGME_00805 2.4e-135 ais G Phosphoglycerate mutase
JPBFLGME_00806 7.9e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JPBFLGME_00807 7.2e-101 acmA 3.2.1.17 NU amidase activity
JPBFLGME_00808 5.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JPBFLGME_00809 1.9e-69 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JPBFLGME_00810 8.4e-281 dnaK O Heat shock 70 kDa protein
JPBFLGME_00811 2.8e-181 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JPBFLGME_00812 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JPBFLGME_00813 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
JPBFLGME_00814 3.3e-72 hmpT S cog cog4720
JPBFLGME_00815 8.7e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JPBFLGME_00816 2.2e-185 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JPBFLGME_00817 0.0 dnaE 2.7.7.7 L DNA polymerase
JPBFLGME_00818 1.3e-150 sua5 2.7.7.87 J Belongs to the SUA5 family
JPBFLGME_00819 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JPBFLGME_00820 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JPBFLGME_00821 2.5e-43 ysdA L Membrane
JPBFLGME_00822 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JPBFLGME_00823 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JPBFLGME_00824 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JPBFLGME_00825 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
JPBFLGME_00827 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JPBFLGME_00828 1.3e-91 ypmS S Protein conserved in bacteria
JPBFLGME_00829 1.3e-85 ypmR E lipolytic protein G-D-S-L family
JPBFLGME_00830 3.8e-45 ypmR E COG2755 Lysophospholipase L1 and related esterases
JPBFLGME_00831 3.3e-147 DegV S DegV family
JPBFLGME_00832 2.9e-304 recN L May be involved in recombinational repair of damaged DNA
JPBFLGME_00833 3.7e-73 argR K Regulates arginine biosynthesis genes
JPBFLGME_00834 4.7e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JPBFLGME_00835 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JPBFLGME_00836 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
JPBFLGME_00837 3.4e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JPBFLGME_00838 2.5e-07 KT response to antibiotic
JPBFLGME_00840 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JPBFLGME_00841 1.5e-124 dnaD
JPBFLGME_00842 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JPBFLGME_00843 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JPBFLGME_00844 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
JPBFLGME_00845 9.7e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JPBFLGME_00846 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JPBFLGME_00847 3.9e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JPBFLGME_00848 2.7e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JPBFLGME_00849 7.3e-232 rodA D Belongs to the SEDS family
JPBFLGME_00850 2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
JPBFLGME_00851 8e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JPBFLGME_00852 2e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JPBFLGME_00853 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JPBFLGME_00854 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JPBFLGME_00855 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JPBFLGME_00856 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JPBFLGME_00857 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JPBFLGME_00858 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JPBFLGME_00859 8.2e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JPBFLGME_00861 2e-31 XK27_08085
JPBFLGME_00862 8.4e-88 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
JPBFLGME_00863 7.9e-10 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
JPBFLGME_00864 5.8e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
JPBFLGME_00865 3.4e-120 ylfI S tigr01906
JPBFLGME_00866 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JPBFLGME_00867 5.7e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
JPBFLGME_00868 6.9e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
JPBFLGME_00871 9.6e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JPBFLGME_00872 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
JPBFLGME_00873 5.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JPBFLGME_00874 4.5e-205 yurR 1.4.5.1 E oxidoreductase
JPBFLGME_00875 2.3e-100 zupT P Mediates zinc uptake. May also transport other divalent cations
JPBFLGME_00876 7e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
JPBFLGME_00877 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JPBFLGME_00878 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
JPBFLGME_00879 1.3e-70 gtrA S GtrA-like protein
JPBFLGME_00880 8.2e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JPBFLGME_00881 4.3e-167 ybbR S Protein conserved in bacteria
JPBFLGME_00882 2.8e-123 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JPBFLGME_00883 7e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
JPBFLGME_00884 8.7e-150 cobQ S glutamine amidotransferase
JPBFLGME_00885 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JPBFLGME_00886 3.1e-130 pip 1.11.1.10 S Alpha beta hydrolase
JPBFLGME_00888 0.0 uup S abc transporter atp-binding protein
JPBFLGME_00889 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
JPBFLGME_00890 1.9e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
JPBFLGME_00891 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JPBFLGME_00892 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
JPBFLGME_00893 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JPBFLGME_00894 7.9e-39 ptsH G phosphocarrier protein Hpr
JPBFLGME_00895 8.2e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
JPBFLGME_00896 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
JPBFLGME_00897 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JPBFLGME_00898 8.5e-34 nrdH O Glutaredoxin
JPBFLGME_00899 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JPBFLGME_00900 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JPBFLGME_00902 4.2e-71 L Transposase (IS116 IS110 IS902 family)
JPBFLGME_00903 8.8e-60 L Transposase (IS116 IS110 IS902 family)
JPBFLGME_00904 5.3e-165 ypuA S secreted protein
JPBFLGME_00905 9.8e-52 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
JPBFLGME_00906 1.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
JPBFLGME_00907 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JPBFLGME_00908 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JPBFLGME_00909 8.3e-257 noxE P NADH oxidase
JPBFLGME_00910 3.6e-293 yfmM S abc transporter atp-binding protein
JPBFLGME_00911 4.8e-59 XK27_01265 S ECF-type riboflavin transporter, S component
JPBFLGME_00912 1.5e-10 XK27_01265 S ECF-type riboflavin transporter, S component
JPBFLGME_00913 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
JPBFLGME_00914 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
JPBFLGME_00915 2e-86 S ECF-type riboflavin transporter, S component
JPBFLGME_00917 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JPBFLGME_00918 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
JPBFLGME_00920 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JPBFLGME_00921 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPBFLGME_00922 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JPBFLGME_00923 0.0 smc D Required for chromosome condensation and partitioning
JPBFLGME_00924 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JPBFLGME_00925 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JPBFLGME_00926 3.6e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JPBFLGME_00927 1.7e-78 alkD L Dna alkylation repair
JPBFLGME_00928 2.8e-93 pat 2.3.1.183 M acetyltransferase
JPBFLGME_00929 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JPBFLGME_00930 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JPBFLGME_00931 3.9e-37 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
JPBFLGME_00932 1.6e-20 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
JPBFLGME_00933 2e-88 proW P Binding-protein-dependent transport system inner membrane component
JPBFLGME_00934 1.6e-137 proV E abc transporter atp-binding protein
JPBFLGME_00935 3.8e-165 proX M ABC transporter, substrate-binding protein, QAT family
JPBFLGME_00936 2.3e-103 proWZ P ABC transporter (Permease
JPBFLGME_00937 2.5e-278 hutH 4.3.1.3 E Histidine ammonia-lyase
JPBFLGME_00938 1.6e-205 S Protein of unknown function (DUF917)
JPBFLGME_00939 2.5e-308 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JPBFLGME_00940 4.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
JPBFLGME_00941 1.3e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPBFLGME_00942 6e-186 desK 2.7.13.3 T Histidine kinase
JPBFLGME_00943 2.6e-132 yvfS V ABC-2 type transporter
JPBFLGME_00944 7.4e-158 XK27_09825 V abc transporter atp-binding protein
JPBFLGME_00948 3.3e-212 EGP Major facilitator Superfamily
JPBFLGME_00949 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
JPBFLGME_00950 7.9e-152 mutR K Transcriptional activator, Rgg GadR MutR family
JPBFLGME_00951 4.6e-42 3.6.1.55 F NUDIX domain
JPBFLGME_00953 3.7e-122 S An automated process has identified a potential problem with this gene model
JPBFLGME_00954 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
JPBFLGME_00955 1.6e-14 liaI KT membrane
JPBFLGME_00956 5.8e-30 liaI KT membrane
JPBFLGME_00957 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
JPBFLGME_00958 0.0 V ABC transporter (permease)
JPBFLGME_00959 1.9e-133 macB2 V ABC transporter, ATP-binding protein
JPBFLGME_00960 6.2e-166 T Histidine kinase
JPBFLGME_00961 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPBFLGME_00962 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JPBFLGME_00963 3.3e-69 pbuX F xanthine permease
JPBFLGME_00964 5.9e-115 pbuX F xanthine permease
JPBFLGME_00965 4.5e-247 norM V Multidrug efflux pump
JPBFLGME_00966 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JPBFLGME_00967 6.6e-235 brnQ E Component of the transport system for branched-chain amino acids
JPBFLGME_00968 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
JPBFLGME_00969 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
JPBFLGME_00970 4.8e-25 csbD K CsbD-like
JPBFLGME_00971 1.8e-227 yfnA E amino acid
JPBFLGME_00972 4e-69 S dextransucrase activity
JPBFLGME_00973 6.3e-14 S dextransucrase activity
JPBFLGME_00974 8.8e-39 S dextransucrase activity
JPBFLGME_00975 9.4e-139 S dextransucrase activity
JPBFLGME_00979 6.9e-136 tcyC2 3.6.3.21 E abc transporter atp-binding protein
JPBFLGME_00980 3e-114 yxeN P ABC transporter, permease protein
JPBFLGME_00981 6.1e-107 ytmL P ABC transporter (Permease
JPBFLGME_00982 2.4e-161 ET ABC transporter substrate-binding protein
JPBFLGME_00983 8.1e-161 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
JPBFLGME_00984 1.1e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JPBFLGME_00985 2.4e-40 S Sugar efflux transporter for intercellular exchange
JPBFLGME_00986 5.9e-23 P FtsX-like permease family
JPBFLGME_00987 3.2e-91 V abc transporter atp-binding protein
JPBFLGME_00988 3.9e-82 K WHG domain
JPBFLGME_00989 9.4e-68 ydhF S Aldo keto reductase
JPBFLGME_00990 2.1e-71 ydhF S Aldo keto reductase
JPBFLGME_00992 7.4e-109 XK27_02070 S nitroreductase
JPBFLGME_00993 2.7e-149 1.13.11.2 S glyoxalase
JPBFLGME_00994 3.6e-76 ywnA K Transcriptional regulator
JPBFLGME_00995 1.3e-154 E Alpha/beta hydrolase of unknown function (DUF915)
JPBFLGME_00996 4.3e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JPBFLGME_00997 1.4e-110 drgA C Nitroreductase
JPBFLGME_00998 9.9e-98 yoaK S Protein of unknown function (DUF1275)
JPBFLGME_00999 6.8e-161 yvgN C reductase
JPBFLGME_01000 7.5e-180 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JPBFLGME_01001 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
JPBFLGME_01003 4.8e-55 K response regulator
JPBFLGME_01004 2.5e-31 S Signal peptide protein, YSIRK family
JPBFLGME_01005 2.6e-31 S Signal peptide protein, YSIRK family
JPBFLGME_01007 3.2e-59
JPBFLGME_01008 2.5e-264 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPBFLGME_01009 6.5e-117
JPBFLGME_01010 2.9e-16
JPBFLGME_01011 0.0 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
JPBFLGME_01012 1.6e-73 3.1.21.3 V Type I restriction modification DNA specificity domain
JPBFLGME_01013 3e-292 hsdM 2.1.1.72 V Type I restriction-modification system
JPBFLGME_01014 0.0 M family 8
JPBFLGME_01015 1.5e-37 L transposase activity
JPBFLGME_01016 5.1e-40 L transposition
JPBFLGME_01017 2.2e-61 L Transposase and inactivated derivatives
JPBFLGME_01018 1.9e-69 IQ PFAM AMP-dependent synthetase and ligase
JPBFLGME_01019 3.5e-106 MA20_06410 E LysE type translocator
JPBFLGME_01020 1e-31
JPBFLGME_01021 0.0 sbcC L ATPase involved in DNA repair
JPBFLGME_01022 7.6e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JPBFLGME_01023 0.0 lacL 3.2.1.23 G -beta-galactosidase
JPBFLGME_01024 0.0 lacS G transporter
JPBFLGME_01025 8.7e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JPBFLGME_01026 2.1e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JPBFLGME_01027 5.4e-286 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
JPBFLGME_01028 1.1e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JPBFLGME_01029 1.3e-182 galR K Transcriptional regulator
JPBFLGME_01030 1.2e-08 L Integrase core domain protein
JPBFLGME_01031 6.7e-24 L transposition
JPBFLGME_01032 8.1e-258 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
JPBFLGME_01033 6.5e-102 V abc transporter atp-binding protein
JPBFLGME_01034 2.1e-39 V (ABC) transporter
JPBFLGME_01035 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
JPBFLGME_01037 1.4e-273 S Protein of unknown function (DUF3114)
JPBFLGME_01038 1.4e-50 2.3.1.128 K Acetyltransferase GNAT Family
JPBFLGME_01039 5.6e-133 V (ABC) transporter
JPBFLGME_01040 1.4e-44 V (ABC) transporter
JPBFLGME_01041 1e-156 C Arylsulfatase regulator (Fe-S oxidoreductase)
JPBFLGME_01042 2e-11 C Arylsulfatase regulator (Fe-S oxidoreductase)
JPBFLGME_01043 7.9e-100 K sequence-specific DNA binding
JPBFLGME_01044 4.3e-18 L COG2801 Transposase and inactivated derivatives
JPBFLGME_01045 1.5e-116 L COG2801 Transposase and inactivated derivatives
JPBFLGME_01046 1.3e-32 L transposase activity
JPBFLGME_01047 5.9e-25 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JPBFLGME_01048 2.1e-82 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPBFLGME_01049 1e-11 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPBFLGME_01050 6.9e-57 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPBFLGME_01051 3.6e-117 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
JPBFLGME_01052 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JPBFLGME_01053 2.5e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JPBFLGME_01054 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JPBFLGME_01055 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JPBFLGME_01058 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JPBFLGME_01059 3.8e-174 vraS 2.7.13.3 T Histidine kinase
JPBFLGME_01060 9.1e-119 yvqF KT membrane
JPBFLGME_01061 2.9e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
JPBFLGME_01062 3.2e-130 stp 3.1.3.16 T phosphatase
JPBFLGME_01063 1.7e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JPBFLGME_01064 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JPBFLGME_01065 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JPBFLGME_01066 1.1e-44 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
JPBFLGME_01067 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JPBFLGME_01068 1.3e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JPBFLGME_01069 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
JPBFLGME_01070 2.1e-148 supH S overlaps another CDS with the same product name
JPBFLGME_01071 8.6e-63 yvoA_1 K Transcriptional
JPBFLGME_01072 9.8e-121 skfE V abc transporter atp-binding protein
JPBFLGME_01073 5.6e-133 V ATPase activity
JPBFLGME_01074 8e-171 oppF P Belongs to the ABC transporter superfamily
JPBFLGME_01075 7.1e-203 oppD P Belongs to the ABC transporter superfamily
JPBFLGME_01076 3.1e-167 amiD P ABC transporter (Permease
JPBFLGME_01077 4.2e-270 amiC P ABC transporter (Permease
JPBFLGME_01078 0.0 amiA E ABC transporter, substrate-binding protein, family 5
JPBFLGME_01079 1.2e-24 oppF P Belongs to the ABC transporter superfamily
JPBFLGME_01080 5e-45 oppF P Belongs to the ABC transporter superfamily
JPBFLGME_01081 1.4e-40 tatD L Hydrolase, tatd
JPBFLGME_01082 9.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
JPBFLGME_01083 3.2e-59 L Integrase core domain protein
JPBFLGME_01084 2.9e-18 L Transposase
JPBFLGME_01085 1.6e-77 sigH K DNA-templated transcription, initiation
JPBFLGME_01086 1.6e-146 ykuT M mechanosensitive ion channel
JPBFLGME_01087 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JPBFLGME_01088 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JPBFLGME_01089 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JPBFLGME_01090 4.2e-83 XK27_03960 S Protein of unknown function (DUF3013)
JPBFLGME_01091 3.1e-80 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
JPBFLGME_01092 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
JPBFLGME_01093 3.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JPBFLGME_01094 1.5e-35 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JPBFLGME_01095 8.6e-45 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JPBFLGME_01096 2.1e-21 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JPBFLGME_01097 1e-241 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JPBFLGME_01098 8.2e-96 nrdI F Belongs to the NrdI family
JPBFLGME_01099 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JPBFLGME_01100 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JPBFLGME_01101 2e-08 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JPBFLGME_01102 3e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JPBFLGME_01103 2.3e-18 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JPBFLGME_01104 1.7e-39 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
JPBFLGME_01105 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JPBFLGME_01106 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JPBFLGME_01107 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JPBFLGME_01108 1.4e-201 yhjX P Major Facilitator
JPBFLGME_01109 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JPBFLGME_01110 5e-94 V VanZ like family
JPBFLGME_01113 1e-123 glnQ E abc transporter atp-binding protein
JPBFLGME_01114 1.8e-276 glnP P ABC transporter
JPBFLGME_01115 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JPBFLGME_01116 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JPBFLGME_01117 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
JPBFLGME_01118 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JPBFLGME_01119 6.3e-235 sufD O assembly protein SufD
JPBFLGME_01120 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JPBFLGME_01121 4.7e-73 nifU C SUF system FeS assembly protein, NifU family
JPBFLGME_01122 2.2e-273 sufB O assembly protein SufB
JPBFLGME_01123 9.7e-19 oppA E ABC transporter substrate-binding protein
JPBFLGME_01124 8.8e-139 oppA E ABC transporter substrate-binding protein
JPBFLGME_01125 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPBFLGME_01127 6.2e-61 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JPBFLGME_01128 7.3e-189 oppD P Belongs to the ABC transporter superfamily
JPBFLGME_01129 8.1e-163 oppF P Belongs to the ABC transporter superfamily
JPBFLGME_01131 5.6e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JPBFLGME_01132 1.3e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JPBFLGME_01133 6e-128 K sequence-specific DNA binding
JPBFLGME_01134 1.5e-106 KLT serine threonine protein kinase
JPBFLGME_01135 0.0 KLT serine threonine protein kinase
JPBFLGME_01136 1.9e-223 EGP Major facilitator Superfamily
JPBFLGME_01137 3.1e-72 adcR K transcriptional
JPBFLGME_01138 2.2e-136 adcC P ABC transporter, ATP-binding protein
JPBFLGME_01139 1.9e-128 adcB P ABC transporter (Permease
JPBFLGME_01140 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
JPBFLGME_01141 1.3e-64 ptsG 2.7.1.199, 2.7.1.208 G pts system
JPBFLGME_01142 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
JPBFLGME_01143 4.2e-257 ptsG 2.7.1.199, 2.7.1.208 G pts system
JPBFLGME_01144 9.8e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
JPBFLGME_01145 3.4e-255 pgi 5.3.1.9 G Belongs to the GPI family
JPBFLGME_01146 1.2e-126 yeeN K transcriptional regulatory protein
JPBFLGME_01147 9.8e-50 yajC U protein transport
JPBFLGME_01148 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JPBFLGME_01149 1.4e-144 cdsA 2.7.7.41 S Belongs to the CDS family
JPBFLGME_01150 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JPBFLGME_01151 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JPBFLGME_01152 0.0 WQ51_06230 S ABC transporter substrate binding protein
JPBFLGME_01153 1.3e-140 cmpC S abc transporter atp-binding protein
JPBFLGME_01154 1e-39 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JPBFLGME_01155 2.5e-284 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JPBFLGME_01156 1.3e-58 L Transposase
JPBFLGME_01157 1e-16 L Transposase
JPBFLGME_01158 2.3e-48 L transposition
JPBFLGME_01159 1.3e-31 L Integrase core domain protein
JPBFLGME_01162 5.3e-16
JPBFLGME_01163 1.7e-54 S TM2 domain
JPBFLGME_01164 3.1e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JPBFLGME_01165 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPBFLGME_01166 2.2e-24 secE U Belongs to the SecE SEC61-gamma family
JPBFLGME_01167 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
JPBFLGME_01168 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
JPBFLGME_01169 4e-47 cof Q phosphatase activity
JPBFLGME_01170 2.1e-35 cof Q phosphatase activity
JPBFLGME_01171 1.9e-98 glcR K transcriptional regulator (DeoR family)
JPBFLGME_01172 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JPBFLGME_01173 3.5e-71 K transcriptional
JPBFLGME_01174 2.2e-232 S COG1073 Hydrolases of the alpha beta superfamily
JPBFLGME_01175 2.7e-274 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JPBFLGME_01176 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JPBFLGME_01177 1.1e-69 yhaI L Membrane
JPBFLGME_01178 2.7e-252 pepC 3.4.22.40 E aminopeptidase
JPBFLGME_01179 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPBFLGME_01180 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JPBFLGME_01181 3.1e-95 ypsA S Belongs to the UPF0398 family
JPBFLGME_01182 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JPBFLGME_01183 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JPBFLGME_01184 1.7e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
JPBFLGME_01185 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
JPBFLGME_01186 2.5e-23
JPBFLGME_01187 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JPBFLGME_01188 3.3e-80 XK27_09675 K -acetyltransferase
JPBFLGME_01189 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JPBFLGME_01190 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JPBFLGME_01191 2.6e-88 L Integrase core domain protein
JPBFLGME_01192 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JPBFLGME_01193 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JPBFLGME_01194 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JPBFLGME_01195 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
JPBFLGME_01196 2.9e-93 ybhL S Belongs to the BI1 family
JPBFLGME_01199 8.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JPBFLGME_01200 4.5e-89 K transcriptional regulator
JPBFLGME_01201 7.6e-36 yneF S UPF0154 protein
JPBFLGME_01202 1.9e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JPBFLGME_01203 8.7e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JPBFLGME_01204 1.7e-98 XK27_09740 S Phosphoesterase
JPBFLGME_01205 2.7e-85 ykuL S CBS domain
JPBFLGME_01206 2.8e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
JPBFLGME_01207 1.5e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JPBFLGME_01208 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JPBFLGME_01209 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JPBFLGME_01210 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JPBFLGME_01211 1.4e-254 trkH P Cation transport protein
JPBFLGME_01212 1.4e-245 trkA P Potassium transporter peripheral membrane component
JPBFLGME_01213 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JPBFLGME_01214 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JPBFLGME_01215 6.5e-111 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
JPBFLGME_01216 5.6e-161 K sequence-specific DNA binding
JPBFLGME_01217 2.1e-32 V protein secretion by the type I secretion system
JPBFLGME_01218 5.5e-105 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPBFLGME_01219 4.4e-56 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPBFLGME_01220 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
JPBFLGME_01221 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JPBFLGME_01222 2.9e-232 cinA 3.5.1.42 S Belongs to the CinA family
JPBFLGME_01223 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
JPBFLGME_01224 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JPBFLGME_01226 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JPBFLGME_01228 5.4e-69 K LytTr DNA-binding domain
JPBFLGME_01229 2.3e-78 S Protein of unknown function (DUF3021)
JPBFLGME_01230 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JPBFLGME_01231 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JPBFLGME_01232 8.2e-70 argR K Regulates arginine biosynthesis genes
JPBFLGME_01233 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
JPBFLGME_01234 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JPBFLGME_01235 6.6e-34
JPBFLGME_01236 5.6e-86 1.1.1.169 H Ketopantoate reductase
JPBFLGME_01237 9.3e-46 1.1.1.169 H Ketopantoate reductase
JPBFLGME_01238 1.9e-203 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JPBFLGME_01239 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JPBFLGME_01240 2e-241 purD 6.3.4.13 F Belongs to the GARS family
JPBFLGME_01241 7.5e-160 S CHAP domain
JPBFLGME_01242 3.8e-31 L Integrase core domain protein
JPBFLGME_01243 1e-51 L transposition
JPBFLGME_01244 1.8e-78 L transposase activity
JPBFLGME_01245 2.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JPBFLGME_01246 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JPBFLGME_01247 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JPBFLGME_01248 1.4e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
JPBFLGME_01249 1.5e-103 yjbK S Adenylate cyclase
JPBFLGME_01250 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JPBFLGME_01251 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
JPBFLGME_01252 1.2e-58 XK27_04120 S Putative amino acid metabolism
JPBFLGME_01253 6.3e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JPBFLGME_01254 2.7e-123 puuD T peptidase C26
JPBFLGME_01255 3.9e-114 radC E Belongs to the UPF0758 family
JPBFLGME_01256 0.0 rgpF M Rhamnan synthesis protein F
JPBFLGME_01257 3.1e-195 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JPBFLGME_01258 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JPBFLGME_01259 1.4e-142 rgpC GM Transport permease protein
JPBFLGME_01260 6.3e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
JPBFLGME_01261 3.5e-224 rgpA GT4 M Domain of unknown function (DUF1972)
JPBFLGME_01262 6.4e-141 S Predicted membrane protein (DUF2142)
JPBFLGME_01263 2.6e-183 tagF 2.7.8.12 M Glycosyl transferase, family 2
JPBFLGME_01264 5.8e-220 amrA S polysaccharide biosynthetic process
JPBFLGME_01265 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
JPBFLGME_01266 2.2e-125 ycbB S Glycosyl transferase family 2
JPBFLGME_01267 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JPBFLGME_01268 1.9e-245
JPBFLGME_01269 1.8e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
JPBFLGME_01270 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
JPBFLGME_01271 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JPBFLGME_01272 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JPBFLGME_01273 4.3e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JPBFLGME_01274 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JPBFLGME_01275 4.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
JPBFLGME_01276 7.5e-200 arcT 2.6.1.1 E Aminotransferase
JPBFLGME_01277 4.7e-135 ET ABC transporter
JPBFLGME_01278 1.7e-140 ET Belongs to the bacterial solute-binding protein 3 family
JPBFLGME_01279 2.9e-84 mutT 3.6.1.55 F Nudix family
JPBFLGME_01280 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JPBFLGME_01282 4.3e-82 S CAAX amino terminal protease family protein
JPBFLGME_01283 2.4e-33 S CAAX amino terminal protease family protein
JPBFLGME_01284 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
JPBFLGME_01285 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPBFLGME_01286 1.1e-16 XK27_00735
JPBFLGME_01287 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JPBFLGME_01289 3.1e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JPBFLGME_01292 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
JPBFLGME_01293 6.7e-50 ycaO O OsmC-like protein
JPBFLGME_01295 3.2e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
JPBFLGME_01297 5.3e-113 serB 3.1.3.3 E phosphoserine phosphatase
JPBFLGME_01298 9.6e-303 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JPBFLGME_01299 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JPBFLGME_01300 1.6e-97 3.1.3.18 S IA, variant 1
JPBFLGME_01301 2.2e-117 lrgB M effector of murein hydrolase
JPBFLGME_01302 7.7e-56 lrgA S Effector of murein hydrolase LrgA
JPBFLGME_01304 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
JPBFLGME_01305 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
JPBFLGME_01306 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JPBFLGME_01307 1.3e-104 wecD M Acetyltransferase (GNAT) domain
JPBFLGME_01308 5.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JPBFLGME_01309 1.2e-45 GK ROK family
JPBFLGME_01310 1.6e-12 GK ROK family
JPBFLGME_01311 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
JPBFLGME_01312 6.6e-62 XK27_08050 O stress-induced mitochondrial fusion
JPBFLGME_01313 6.2e-13 XK27_08050 O HflC and HflK could regulate a protease
JPBFLGME_01314 3.9e-75 XK27_01300 S ASCH
JPBFLGME_01316 7.3e-51 S Toxin-antitoxin system, toxin component, RelE family
JPBFLGME_01317 2e-29 K Helix-turn-helix XRE-family like proteins
JPBFLGME_01318 7.5e-09 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JPBFLGME_01319 1.1e-12
JPBFLGME_01320 6.5e-64 V MatE
JPBFLGME_01321 1.6e-101 V MatE
JPBFLGME_01323 3.9e-110 C Fe-S oxidoreductases
JPBFLGME_01324 1.2e-176 EGP Major Facilitator Superfamily
JPBFLGME_01325 5.5e-258 I radical SAM domain protein
JPBFLGME_01327 3.2e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JPBFLGME_01328 1.4e-150 L Integrase core domain protein
JPBFLGME_01329 1.8e-87 L transposase activity
JPBFLGME_01331 1.9e-107
JPBFLGME_01332 7.4e-90
JPBFLGME_01333 4.5e-21 XK27_08050 O HflC and HflK could regulate a protease
JPBFLGME_01335 2.3e-206 potD P spermidine putrescine ABC transporter
JPBFLGME_01336 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
JPBFLGME_01337 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
JPBFLGME_01338 2.8e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JPBFLGME_01339 7.8e-171 murB 1.3.1.98 M cell wall formation
JPBFLGME_01340 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JPBFLGME_01341 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JPBFLGME_01342 3e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
JPBFLGME_01343 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JPBFLGME_01344 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
JPBFLGME_01345 0.0 ydaO E amino acid
JPBFLGME_01346 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JPBFLGME_01347 4.1e-37 ylqC L Belongs to the UPF0109 family
JPBFLGME_01348 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JPBFLGME_01349 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
JPBFLGME_01350 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
JPBFLGME_01351 2.1e-74 S QueT transporter
JPBFLGME_01352 1.7e-119 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
JPBFLGME_01353 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JPBFLGME_01354 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JPBFLGME_01355 1.3e-85 ccl S cog cog4708
JPBFLGME_01356 2.4e-159 rbn E Belongs to the UPF0761 family
JPBFLGME_01357 7.2e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
JPBFLGME_01358 2.8e-230 ytoI K transcriptional regulator containing CBS domains
JPBFLGME_01359 4.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
JPBFLGME_01360 1.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JPBFLGME_01361 0.0 comEC S Competence protein ComEC
JPBFLGME_01362 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
JPBFLGME_01363 1.7e-142 plsC 2.3.1.51 I Acyltransferase
JPBFLGME_01364 1.8e-140 nodB3 G deacetylase
JPBFLGME_01365 2.7e-140 yabB 2.1.1.223 L Methyltransferase
JPBFLGME_01366 1e-41 yazA L endonuclease containing a URI domain
JPBFLGME_01367 1.1e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JPBFLGME_01368 2.3e-22 corA P CorA-like protein
JPBFLGME_01369 2.6e-112 corA P CorA-like protein
JPBFLGME_01370 2.5e-62 yjqA S Bacterial PH domain
JPBFLGME_01371 5.6e-98 thiT S Thiamine transporter
JPBFLGME_01372 1.4e-153 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JPBFLGME_01373 3.1e-64 yjbB G Permeases of the major facilitator superfamily
JPBFLGME_01374 1.4e-84 yjbB G Permeases of the major facilitator superfamily
JPBFLGME_01375 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JPBFLGME_01376 7.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
JPBFLGME_01377 5.7e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JPBFLGME_01380 1.1e-155 cjaA ET ABC transporter substrate-binding protein
JPBFLGME_01381 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
JPBFLGME_01382 3e-106 P ABC transporter (Permease
JPBFLGME_01383 3.9e-114 papP P ABC transporter (Permease
JPBFLGME_01384 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JPBFLGME_01385 3e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
JPBFLGME_01386 0.0 copA 3.6.3.54 P P-type ATPase
JPBFLGME_01387 2.7e-73 copY K Copper transport repressor, CopY TcrY family
JPBFLGME_01388 6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JPBFLGME_01389 3.8e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JPBFLGME_01390 1.1e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
JPBFLGME_01391 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JPBFLGME_01392 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JPBFLGME_01393 2e-103 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
JPBFLGME_01394 4.6e-252 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JPBFLGME_01395 1.5e-35 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
JPBFLGME_01396 1.1e-35
JPBFLGME_01397 0.0 ctpE P E1-E2 ATPase
JPBFLGME_01398 2.1e-60
JPBFLGME_01399 6.5e-27
JPBFLGME_01400 1.1e-99 fic D Fic/DOC family
JPBFLGME_01401 4.3e-33 L Transposase
JPBFLGME_01402 2e-83 norB P Major facilitator superfamily
JPBFLGME_01403 8.2e-27 S Membrane
JPBFLGME_01404 3.3e-31
JPBFLGME_01405 4.5e-39
JPBFLGME_01406 9.7e-22 S Small integral membrane protein
JPBFLGME_01407 9e-77 M Protein conserved in bacteria
JPBFLGME_01408 1e-09 K CsbD-like
JPBFLGME_01409 6.7e-125 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JPBFLGME_01410 1.4e-135 HJ the current gene model (or a revised gene model) may contain a frame shift
JPBFLGME_01411 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JPBFLGME_01412 5.1e-47 L transposase activity
JPBFLGME_01413 6e-121 K transcriptional regulator, MerR family
JPBFLGME_01414 1.3e-102 dnaQ 2.7.7.7 L DNA polymerase III
JPBFLGME_01415 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
JPBFLGME_01416 4.8e-63 XK27_02560 S cog cog2151
JPBFLGME_01417 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JPBFLGME_01418 1e-226 ytfP S Flavoprotein
JPBFLGME_01420 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JPBFLGME_01421 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
JPBFLGME_01422 4.3e-181 ecsB U ABC transporter
JPBFLGME_01423 1.1e-130 ecsA V abc transporter atp-binding protein
JPBFLGME_01424 2.5e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JPBFLGME_01425 1.9e-09
JPBFLGME_01427 6.9e-19
JPBFLGME_01428 6.3e-07
JPBFLGME_01429 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
JPBFLGME_01430 1.9e-200 ylbM S Belongs to the UPF0348 family
JPBFLGME_01431 1.3e-139 yqeM Q Methyltransferase domain protein
JPBFLGME_01432 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JPBFLGME_01433 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JPBFLGME_01434 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JPBFLGME_01435 3.5e-49 yhbY J RNA-binding protein
JPBFLGME_01436 7.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JPBFLGME_01437 1.8e-98 yqeG S hydrolase of the HAD superfamily
JPBFLGME_01438 2.1e-62 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JPBFLGME_01439 4.5e-80 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JPBFLGME_01440 1.6e-64
JPBFLGME_01441 5.1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JPBFLGME_01442 7.7e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JPBFLGME_01443 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JPBFLGME_01444 7.3e-258 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JPBFLGME_01445 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JPBFLGME_01446 4.8e-154 hlpA M Belongs to the NlpA lipoprotein family
JPBFLGME_01447 7.5e-100 pncA Q isochorismatase
JPBFLGME_01448 2.8e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JPBFLGME_01449 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
JPBFLGME_01450 6.9e-75 XK27_03180 T universal stress protein
JPBFLGME_01452 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JPBFLGME_01453 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
JPBFLGME_01454 2.1e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
JPBFLGME_01455 0.0 yjcE P NhaP-type Na H and K H antiporters
JPBFLGME_01457 2e-97 ytqB 2.1.1.176 J (SAM)-dependent
JPBFLGME_01458 1.3e-179 yhcC S radical SAM protein
JPBFLGME_01459 7.8e-194 ylbL T Belongs to the peptidase S16 family
JPBFLGME_01460 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JPBFLGME_01461 4.3e-92 rsmD 2.1.1.171 L Methyltransferase
JPBFLGME_01462 5.5e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JPBFLGME_01463 1.1e-09 S Protein of unknown function (DUF4059)
JPBFLGME_01464 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
JPBFLGME_01465 2.3e-162 yxeN P ABC transporter (Permease
JPBFLGME_01466 4.8e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
JPBFLGME_01468 8.8e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JPBFLGME_01469 0.0 pflB 2.3.1.54 C formate acetyltransferase'
JPBFLGME_01470 7.2e-43 cah 4.2.1.1 P carbonic anhydrase
JPBFLGME_01471 5.8e-39 cah 4.2.1.1 P carbonic anhydrase
JPBFLGME_01472 1e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JPBFLGME_01474 1.5e-86 L Plasmid recombination enzyme
JPBFLGME_01475 1.2e-32 L DNA integration
JPBFLGME_01476 4.8e-58 L Phage integrase family
JPBFLGME_01477 7.6e-118 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
JPBFLGME_01478 2.3e-123 ybbM S transport system, permease component
JPBFLGME_01479 6.8e-116 ybbL S abc transporter atp-binding protein
JPBFLGME_01480 3.1e-31
JPBFLGME_01481 1.5e-183 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
JPBFLGME_01482 2.8e-137 cppA E CppA N-terminal
JPBFLGME_01483 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
JPBFLGME_01484 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JPBFLGME_01487 3e-47 spiA K sequence-specific DNA binding
JPBFLGME_01488 9.5e-140 blpT
JPBFLGME_01492 7.4e-135 agrA KT phosphorelay signal transduction system
JPBFLGME_01493 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
JPBFLGME_01495 7.3e-237 mesE M Transport protein ComB
JPBFLGME_01496 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPBFLGME_01497 0.0 mdlB V abc transporter atp-binding protein
JPBFLGME_01498 0.0 mdlA V abc transporter atp-binding protein
JPBFLGME_01500 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
JPBFLGME_01501 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JPBFLGME_01502 2.4e-66 yutD J protein conserved in bacteria
JPBFLGME_01503 9e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JPBFLGME_01505 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JPBFLGME_01506 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JPBFLGME_01507 0.0 ftsI 3.4.16.4 M penicillin-binding protein
JPBFLGME_01508 4.3e-47 ftsL D cell division protein FtsL
JPBFLGME_01509 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JPBFLGME_01510 1.6e-65
JPBFLGME_01511 7.4e-27
JPBFLGME_01512 7.5e-30
JPBFLGME_01513 8.7e-33 yhaI J Protein of unknown function (DUF805)
JPBFLGME_01514 4.5e-18 D nuclear chromosome segregation
JPBFLGME_01515 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JPBFLGME_01516 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JPBFLGME_01517 2e-286 XK27_00765
JPBFLGME_01518 8.1e-134 ecsA_2 V abc transporter atp-binding protein
JPBFLGME_01519 7.6e-12 S Protein of unknown function (DUF554)
JPBFLGME_01520 3.1e-99 S Protein of unknown function (DUF554)
JPBFLGME_01521 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JPBFLGME_01522 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
JPBFLGME_01523 2.4e-55 liaI S membrane
JPBFLGME_01524 2.7e-09 XK27_02470 K LytTr DNA-binding domain protein
JPBFLGME_01525 3e-53 KT response to antibiotic
JPBFLGME_01526 1.4e-08 KT response to antibiotic
JPBFLGME_01527 9.1e-18 KT response to antibiotic
JPBFLGME_01528 9.8e-80 yebC M Membrane
JPBFLGME_01529 1.1e-16 yebC M Membrane
JPBFLGME_01530 1.2e-258 XK27_03190 S hydrolases of the HAD superfamily
JPBFLGME_01531 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JPBFLGME_01532 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JPBFLGME_01533 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JPBFLGME_01534 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JPBFLGME_01535 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JPBFLGME_01536 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JPBFLGME_01537 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JPBFLGME_01539 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
JPBFLGME_01540 5.2e-130 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
JPBFLGME_01541 5.6e-34 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
JPBFLGME_01542 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
JPBFLGME_01543 2.7e-290 scrB 3.2.1.26 GH32 G invertase
JPBFLGME_01544 2.4e-178 scrR K Transcriptional
JPBFLGME_01545 1.6e-84 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
JPBFLGME_01546 2.6e-47 yhaI L Membrane
JPBFLGME_01547 1e-55 S Domain of unknown function (DUF4173)
JPBFLGME_01548 1.2e-94 ureI S AmiS/UreI family transporter
JPBFLGME_01549 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JPBFLGME_01550 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JPBFLGME_01551 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JPBFLGME_01552 6.6e-78 ureE O enzyme active site formation
JPBFLGME_01553 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JPBFLGME_01554 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
JPBFLGME_01555 3.7e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
JPBFLGME_01556 2.7e-177 cbiM P PDGLE domain
JPBFLGME_01557 3.7e-137 P cobalt transport protein
JPBFLGME_01558 1.6e-131 cbiO P ABC transporter
JPBFLGME_01559 5.3e-153 ET amino acid transport
JPBFLGME_01560 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JPBFLGME_01561 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
JPBFLGME_01562 3.8e-205 EGP Transmembrane secretion effector
JPBFLGME_01563 4.5e-144 ET amino acid transport
JPBFLGME_01564 5.8e-158 metQ M Belongs to the NlpA lipoprotein family
JPBFLGME_01565 1.8e-256 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
JPBFLGME_01566 5.2e-182 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JPBFLGME_01567 2e-97 metI P ABC transporter (Permease
JPBFLGME_01568 1.3e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JPBFLGME_01569 4.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
JPBFLGME_01570 8e-94 S UPF0397 protein
JPBFLGME_01571 0.0 ykoD P abc transporter atp-binding protein
JPBFLGME_01572 1.6e-149 cbiQ P cobalt transport
JPBFLGME_01573 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JPBFLGME_01574 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
JPBFLGME_01575 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
JPBFLGME_01576 3.4e-242 P COG0168 Trk-type K transport systems, membrane components
JPBFLGME_01577 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
JPBFLGME_01578 9e-90 yceD K metal-binding, possibly nucleic acid-binding protein
JPBFLGME_01579 3.3e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JPBFLGME_01580 3e-276 T PhoQ Sensor
JPBFLGME_01581 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JPBFLGME_01582 1.9e-217 dnaB L Replication initiation and membrane attachment
JPBFLGME_01583 8.9e-167 dnaI L Primosomal protein DnaI
JPBFLGME_01584 1.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JPBFLGME_01585 4.2e-13 yrdC 3.5.1.19 Q isochorismatase
JPBFLGME_01586 1.4e-27 yrdC 3.5.1.19 Q isochorismatase
JPBFLGME_01587 3.7e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JPBFLGME_01588 3.4e-62 yqhY S protein conserved in bacteria
JPBFLGME_01589 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JPBFLGME_01590 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
JPBFLGME_01591 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
JPBFLGME_01594 6.9e-12 V 'abc transporter, ATP-binding protein
JPBFLGME_01595 1.3e-58 V 'abc transporter, ATP-binding protein
JPBFLGME_01601 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JPBFLGME_01602 5e-168 corA P COG0598 Mg2 and Co2 transporters
JPBFLGME_01603 2e-123 XK27_01040 S Pfam PF06570
JPBFLGME_01605 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JPBFLGME_01606 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JPBFLGME_01607 1.9e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
JPBFLGME_01608 2.8e-41 XK27_05745
JPBFLGME_01610 2.3e-228 mutY L A G-specific adenine glycosylase
JPBFLGME_01613 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JPBFLGME_01614 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JPBFLGME_01615 1e-93 cvpA S toxin biosynthetic process
JPBFLGME_01616 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JPBFLGME_01617 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JPBFLGME_01618 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JPBFLGME_01619 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JPBFLGME_01620 8.8e-48 azlD E branched-chain amino acid
JPBFLGME_01621 8.5e-117 azlC E AzlC protein
JPBFLGME_01622 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JPBFLGME_01623 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JPBFLGME_01624 2.1e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
JPBFLGME_01625 2.5e-33 ykzG S Belongs to the UPF0356 family
JPBFLGME_01626 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JPBFLGME_01627 7.1e-41 pscB M CHAP domain protein
JPBFLGME_01629 9.9e-263 glnA 6.3.1.2 E glutamine synthetase
JPBFLGME_01630 8.5e-63 glnR K Transcriptional regulator
JPBFLGME_01631 1.3e-87 S Fusaric acid resistance protein-like
JPBFLGME_01632 1.5e-12
JPBFLGME_01633 1.7e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JPBFLGME_01634 7.9e-41 L COG1943 Transposase and inactivated derivatives
JPBFLGME_01635 4.2e-28 L Integrase core domain protein
JPBFLGME_01636 4.3e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JPBFLGME_01637 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JPBFLGME_01638 4.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JPBFLGME_01639 5.1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JPBFLGME_01640 7e-142 purR 2.4.2.7 F operon repressor
JPBFLGME_01641 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
JPBFLGME_01642 4.5e-172 rmuC S RmuC domain protein
JPBFLGME_01643 9.2e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
JPBFLGME_01644 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JPBFLGME_01645 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JPBFLGME_01647 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JPBFLGME_01648 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JPBFLGME_01649 4.1e-144 tatD L Hydrolase, tatd
JPBFLGME_01650 1.9e-74 yccU S CoA-binding protein
JPBFLGME_01651 1.1e-50 trxA O Belongs to the thioredoxin family
JPBFLGME_01652 7.8e-143 S Macro domain protein
JPBFLGME_01653 1.8e-10 L thioesterase
JPBFLGME_01654 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
JPBFLGME_01655 9.1e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JPBFLGME_01656 1.1e-83 L Transposase
JPBFLGME_01657 1e-13 rpmH J Ribosomal protein L34
JPBFLGME_01658 1.5e-258 S Uncharacterised protein family (UPF0236)
JPBFLGME_01661 7.9e-12 S TIR domain
JPBFLGME_01662 1.7e-69 M Filamentation induced by cAMP protein fic
JPBFLGME_01664 9.2e-89 D CobQ CobB MinD ParA nucleotide binding domain protein
JPBFLGME_01665 8.6e-232 S Psort location CytoplasmicMembrane, score
JPBFLGME_01667 2.2e-81 tnpR L Resolvase, N terminal domain
JPBFLGME_01669 2.9e-277 U relaxase
JPBFLGME_01670 3.7e-26 S Bacterial mobilisation protein (MobC)
JPBFLGME_01672 0.0 2.1.1.72, 3.1.21.3 L Psort location Cytoplasmic, score
JPBFLGME_01674 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JPBFLGME_01677 0.0 U An automated process has identified a potential problem with this gene model
JPBFLGME_01678 8e-45 S Protein of unknown function (DUF3801)
JPBFLGME_01679 8.2e-55
JPBFLGME_01681 3e-63 ssb L single-stranded DNA binding
JPBFLGME_01682 9.1e-99
JPBFLGME_01683 0.0 M CHAP domain protein
JPBFLGME_01684 0.0 U Psort location Cytoplasmic, score
JPBFLGME_01685 1.6e-42 S PrgI family protein
JPBFLGME_01686 1.5e-90
JPBFLGME_01687 4.1e-24
JPBFLGME_01688 8.9e-15
JPBFLGME_01689 0.0 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JPBFLGME_01690 8.6e-20 MU outer membrane autotransporter barrel domain protein
JPBFLGME_01691 7e-13
JPBFLGME_01693 6.2e-87 repA S Replication initiator protein A
JPBFLGME_01696 1.2e-183 jag S RNA-binding protein
JPBFLGME_01697 8.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JPBFLGME_01698 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JPBFLGME_01699 1.2e-263 argH 4.3.2.1 E Argininosuccinate lyase
JPBFLGME_01700 3.4e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JPBFLGME_01701 1.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JPBFLGME_01702 6.7e-81 amiA E transmembrane transport
JPBFLGME_01703 7.3e-69 amiA E transmembrane transport
JPBFLGME_01704 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JPBFLGME_01705 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JPBFLGME_01706 9.2e-51 S Protein of unknown function (DUF3397)
JPBFLGME_01707 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
JPBFLGME_01708 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
JPBFLGME_01709 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
JPBFLGME_01710 1.4e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
JPBFLGME_01711 9.9e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JPBFLGME_01712 2.4e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
JPBFLGME_01713 7e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
JPBFLGME_01714 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
JPBFLGME_01715 7.8e-35 XK27_09620 S FMN reductase (NADPH) activity
JPBFLGME_01716 4.2e-223 XK27_09615 C reductase
JPBFLGME_01718 2.1e-71 fnt P Formate nitrite transporter
JPBFLGME_01719 9e-76 XK27_08585 S Psort location CytoplasmicMembrane, score
JPBFLGME_01720 7e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JPBFLGME_01721 1.7e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JPBFLGME_01722 3.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
JPBFLGME_01723 4.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JPBFLGME_01724 8.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JPBFLGME_01725 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JPBFLGME_01726 1.5e-117 S HAD hydrolase, family IA, variant
JPBFLGME_01727 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
JPBFLGME_01730 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JPBFLGME_01731 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JPBFLGME_01732 4.1e-36 yeeD O sulfur carrier activity
JPBFLGME_01733 3.6e-188 yeeE S Sulphur transport
JPBFLGME_01734 3.9e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JPBFLGME_01735 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JPBFLGME_01736 1.4e-09 S Domain of unknown function (DUF4651)
JPBFLGME_01737 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JPBFLGME_01738 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JPBFLGME_01739 9.6e-110 S CAAX amino terminal protease family protein
JPBFLGME_01741 1.3e-33 V CAAX protease self-immunity
JPBFLGME_01742 1.8e-33 V CAAX protease self-immunity
JPBFLGME_01743 2.6e-26 lanR K sequence-specific DNA binding
JPBFLGME_01744 3.2e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JPBFLGME_01745 4.2e-175 ytxK 2.1.1.72 L DNA methylase
JPBFLGME_01746 2.2e-11 comGF U Putative Competence protein ComGF
JPBFLGME_01747 1.3e-70 comGF U Competence protein ComGF
JPBFLGME_01748 4.1e-15 NU Type II secretory pathway pseudopilin
JPBFLGME_01749 2.6e-56 cglD NU Competence protein
JPBFLGME_01750 2.5e-42 comGC U Required for transformation and DNA binding
JPBFLGME_01751 1e-151 cglB NU type II secretion system
JPBFLGME_01752 6.4e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JPBFLGME_01753 3.2e-67 S cog cog4699
JPBFLGME_01754 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPBFLGME_01755 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPBFLGME_01756 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JPBFLGME_01757 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JPBFLGME_01758 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JPBFLGME_01759 1.1e-75 ilvN 2.2.1.6 E Acetolactate synthase
JPBFLGME_01760 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
JPBFLGME_01761 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JPBFLGME_01762 6.7e-301 yloV S kinase related to dihydroxyacetone kinase
JPBFLGME_01763 1.8e-57 asp S cog cog1302
JPBFLGME_01764 2.7e-225 norN V Mate efflux family protein
JPBFLGME_01765 1.9e-278 thrC 4.2.3.1 E Threonine synthase
JPBFLGME_01766 7.5e-39 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JPBFLGME_01767 5.6e-29 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
JPBFLGME_01768 7e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JPBFLGME_01769 2.1e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JPBFLGME_01770 3.6e-64 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
JPBFLGME_01771 0.0 pepO 3.4.24.71 O Peptidase family M13
JPBFLGME_01772 3.9e-54 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JPBFLGME_01773 1.6e-41 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JPBFLGME_01774 5.5e-80 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JPBFLGME_01775 1.4e-54 treB 2.7.1.201 G PTS System
JPBFLGME_01776 2.2e-20 treR K DNA-binding transcription factor activity
JPBFLGME_01777 3.3e-86 treR K trehalose operon
JPBFLGME_01778 5.7e-95 ywlG S Belongs to the UPF0340 family
JPBFLGME_01781 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
JPBFLGME_01783 2.1e-103 6.3.2.2 H ergothioneine biosynthetic process
JPBFLGME_01784 7.3e-34 6.3.2.2 H gamma-glutamylcysteine synthetase
JPBFLGME_01785 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
JPBFLGME_01786 2.7e-13 L PFAM Integrase, catalytic core
JPBFLGME_01787 1.6e-71 L PFAM Integrase, catalytic core
JPBFLGME_01788 3.3e-62 rplQ J ribosomal protein l17
JPBFLGME_01789 6.2e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JPBFLGME_01790 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JPBFLGME_01791 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JPBFLGME_01792 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JPBFLGME_01793 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JPBFLGME_01794 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JPBFLGME_01795 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JPBFLGME_01796 1.3e-57 rplO J binds to the 23S rRNA
JPBFLGME_01797 2.5e-23 rpmD J ribosomal protein l30
JPBFLGME_01798 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JPBFLGME_01799 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JPBFLGME_01800 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JPBFLGME_01801 1.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JPBFLGME_01802 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JPBFLGME_01803 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JPBFLGME_01804 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JPBFLGME_01805 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JPBFLGME_01806 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JPBFLGME_01807 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
JPBFLGME_01808 1e-69 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JPBFLGME_01809 2.6e-115 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JPBFLGME_01810 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JPBFLGME_01811 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JPBFLGME_01812 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JPBFLGME_01813 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JPBFLGME_01814 2.2e-103 rplD J Forms part of the polypeptide exit tunnel
JPBFLGME_01815 5.3e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JPBFLGME_01816 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
JPBFLGME_01817 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JPBFLGME_01818 0.0 XK27_09800 I Acyltransferase
JPBFLGME_01819 1.7e-35 XK27_09805 S MORN repeat protein
JPBFLGME_01820 5.2e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JPBFLGME_01821 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JPBFLGME_01822 1.1e-89 adk 2.7.4.3 F topology modulation protein
JPBFLGME_01823 2.2e-186 yxaM EGP Major facilitator Superfamily
JPBFLGME_01824 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
JPBFLGME_01826 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
JPBFLGME_01827 0.0 KLT serine threonine protein kinase
JPBFLGME_01828 2.1e-280 V ABC transporter
JPBFLGME_01830 1.1e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
JPBFLGME_01831 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JPBFLGME_01832 2.2e-44 yrzL S Belongs to the UPF0297 family
JPBFLGME_01833 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JPBFLGME_01834 4.2e-44 yrzB S Belongs to the UPF0473 family
JPBFLGME_01835 1.7e-285 ccs S the current gene model (or a revised gene model) may contain a frame shift
JPBFLGME_01836 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
JPBFLGME_01837 7.5e-14
JPBFLGME_01838 9.9e-91 XK27_10930 K acetyltransferase
JPBFLGME_01839 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JPBFLGME_01840 7e-147 yaaA S Belongs to the UPF0246 family
JPBFLGME_01841 9.9e-169 XK27_01785 S cog cog1284
JPBFLGME_01842 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JPBFLGME_01844 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
JPBFLGME_01845 5.7e-52 metE 2.1.1.14 E Methionine synthase
JPBFLGME_01846 7.6e-64 metE 2.1.1.14 E Methionine synthase
JPBFLGME_01847 9.2e-36 metE 2.1.1.14 E Methionine synthase
JPBFLGME_01848 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JPBFLGME_01849 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JPBFLGME_01852 1.7e-23 yegS 2.7.1.107 I lipid kinase activity
JPBFLGME_01854 3.7e-27 S Membrane
JPBFLGME_01855 1.7e-99
JPBFLGME_01856 1.8e-23 S Small integral membrane protein
JPBFLGME_01857 6.5e-83 M Protein conserved in bacteria
JPBFLGME_01858 1.1e-11 K CsbD-like
JPBFLGME_01859 1.1e-107 nudL L hydrolase
JPBFLGME_01860 3e-48 K transcriptional regulator, PadR family
JPBFLGME_01861 9.6e-08 XK27_06920 S Protein of unknown function (DUF1700)
JPBFLGME_01862 9.1e-13 XK27_06920 S Protein of unknown function (DUF1700)
JPBFLGME_01863 3.1e-108 S Putative adhesin
JPBFLGME_01864 4e-158 XK27_06930 V domain protein
JPBFLGME_01865 2.1e-94 XK27_06935 K transcriptional regulator
JPBFLGME_01866 5.5e-11 ypaA M Membrane
JPBFLGME_01867 2e-07
JPBFLGME_01868 4.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JPBFLGME_01869 8.2e-48 veg S Biofilm formation stimulator VEG
JPBFLGME_01870 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JPBFLGME_01871 8.5e-73 rplI J binds to the 23S rRNA
JPBFLGME_01872 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JPBFLGME_01873 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JPBFLGME_01874 2e-74 F NUDIX domain
JPBFLGME_01875 2.4e-214 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JPBFLGME_01876 6.8e-301 S Bacterial membrane protein, YfhO
JPBFLGME_01877 8.2e-44 isaA GH23 M Immunodominant staphylococcal antigen A
JPBFLGME_01878 3.9e-80 lytE M LysM domain protein
JPBFLGME_01879 1e-134 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPBFLGME_01880 4.2e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPBFLGME_01881 1.8e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JPBFLGME_01882 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JPBFLGME_01883 7e-137 ymfM S sequence-specific DNA binding
JPBFLGME_01884 7.4e-228 ymfH S Peptidase M16
JPBFLGME_01885 1.5e-233 ymfF S Peptidase M16
JPBFLGME_01886 3.6e-45 yaaA S S4 domain protein YaaA
JPBFLGME_01887 2.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JPBFLGME_01888 4.7e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JPBFLGME_01889 1.4e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JPBFLGME_01890 5.4e-153 yvjA S membrane
JPBFLGME_01891 6.7e-306 ybiT S abc transporter atp-binding protein
JPBFLGME_01892 0.0 XK27_10405 S Bacterial membrane protein YfhO
JPBFLGME_01896 1.4e-119 yoaK S Psort location CytoplasmicMembrane, score
JPBFLGME_01897 2.5e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JPBFLGME_01898 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
JPBFLGME_01899 1e-134 parB K Belongs to the ParB family
JPBFLGME_01900 4.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JPBFLGME_01901 2.4e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JPBFLGME_01902 4.1e-29 yyzM S Protein conserved in bacteria
JPBFLGME_01903 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JPBFLGME_01904 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JPBFLGME_01905 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JPBFLGME_01906 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JPBFLGME_01907 7.9e-61 divIC D Septum formation initiator
JPBFLGME_01909 9.6e-239 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
JPBFLGME_01910 5.5e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JPBFLGME_01911 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JPBFLGME_01912 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JPBFLGME_01913 1.7e-162 L Transposase
JPBFLGME_01914 5.1e-21 L overlaps another CDS with the same product name
JPBFLGME_01915 2.4e-13 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
JPBFLGME_01916 4.7e-16 K helix_turn_helix, Arsenical Resistance Operon Repressor
JPBFLGME_01917 6.3e-160 yrdR EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JPBFLGME_01918 1.2e-71 2.7.7.12 C Domain of unknown function (DUF4931)
JPBFLGME_01919 6.8e-153 S metal-dependent hydrolase with the TIM-barrel fold
JPBFLGME_01920 7.7e-123 dlpA H Methyltransferase
JPBFLGME_01921 4e-209 dlpA 1.1.1.85 CE Tartrate dehydrogenase
JPBFLGME_01923 8.3e-160 4.1.3.39 E Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds
JPBFLGME_01924 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JPBFLGME_01925 4.2e-62 manO S protein conserved in bacteria
JPBFLGME_01926 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
JPBFLGME_01927 3.9e-116 manM G pts system
JPBFLGME_01928 3.1e-173 manL 2.7.1.191 G pts system
JPBFLGME_01929 4.9e-139 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
JPBFLGME_01930 5.6e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
JPBFLGME_01931 3e-241 pbuO S permease
JPBFLGME_01932 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
JPBFLGME_01933 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
JPBFLGME_01934 5.7e-217 brpA K Transcriptional
JPBFLGME_01935 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
JPBFLGME_01936 3.1e-212 nusA K Participates in both transcription termination and antitermination
JPBFLGME_01937 3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
JPBFLGME_01938 1.4e-41 ylxQ J ribosomal protein
JPBFLGME_01939 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JPBFLGME_01940 6.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JPBFLGME_01941 3.8e-73 yvdD 3.2.2.10 S Belongs to the LOG family
JPBFLGME_01943 5.9e-225 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
JPBFLGME_01944 7.9e-274 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JPBFLGME_01945 1.7e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
JPBFLGME_01946 2.3e-91 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
JPBFLGME_01947 1.1e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
JPBFLGME_01948 2.8e-221 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JPBFLGME_01949 8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
JPBFLGME_01950 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JPBFLGME_01951 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JPBFLGME_01952 1.3e-73 ylbF S Belongs to the UPF0342 family
JPBFLGME_01953 7.1e-46 ylbG S UPF0298 protein
JPBFLGME_01954 9.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
JPBFLGME_01955 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
JPBFLGME_01956 3.2e-138 livM E Belongs to the binding-protein-dependent transport system permease family
JPBFLGME_01957 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
JPBFLGME_01958 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
JPBFLGME_01959 1e-39 acuB S CBS domain
JPBFLGME_01960 9.3e-42 acuB S IMP dehydrogenase activity
JPBFLGME_01961 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JPBFLGME_01962 6.3e-111 yvyE 3.4.13.9 S YigZ family
JPBFLGME_01963 2e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JPBFLGME_01964 4.9e-122 comFC S Competence protein
JPBFLGME_01965 2.4e-90 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JPBFLGME_01967 8.5e-09
JPBFLGME_01968 3.3e-30 S Antidote-toxin recognition MazE, bacterial antitoxin
JPBFLGME_01969 1e-69 doc S Prophage maintenance system killer protein
JPBFLGME_01970 4.1e-242 ltrA_1 L Reverse transcriptase (RNA-dependent DNA polymerase)
JPBFLGME_01971 2.2e-17
JPBFLGME_01972 1.8e-79 tnpR L Resolvase, N terminal domain
JPBFLGME_01973 2.3e-27 S Protein of unknown function (DUF2568)
JPBFLGME_01974 2.6e-52 L Transposase
JPBFLGME_01975 5.4e-197 L transposase, IS4 family
JPBFLGME_01976 4.1e-158 L COG2801 Transposase and inactivated derivatives
JPBFLGME_01977 1e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
JPBFLGME_01978 4.1e-107 S Domain of unknown function (DUF1803)
JPBFLGME_01979 7.8e-102 ygaC J Belongs to the UPF0374 family
JPBFLGME_01980 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
JPBFLGME_01981 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JPBFLGME_01982 6.7e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
JPBFLGME_01983 2e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
JPBFLGME_01984 1.6e-114 S Haloacid dehalogenase-like hydrolase
JPBFLGME_01985 4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
JPBFLGME_01986 4e-72 marR K Transcriptional regulator, MarR family
JPBFLGME_01987 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JPBFLGME_01988 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JPBFLGME_01989 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
JPBFLGME_01990 1.9e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JPBFLGME_01991 1.6e-126 IQ reductase
JPBFLGME_01992 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JPBFLGME_01993 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JPBFLGME_01994 4.3e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JPBFLGME_01995 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JPBFLGME_01996 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JPBFLGME_01997 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JPBFLGME_01998 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JPBFLGME_01999 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
JPBFLGME_02000 1.8e-84 L Transposase
JPBFLGME_02001 1.2e-121 fruR K transcriptional
JPBFLGME_02002 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
JPBFLGME_02003 0.0 fruA 2.7.1.202 G phosphotransferase system
JPBFLGME_02004 3e-259 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JPBFLGME_02005 1.7e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JPBFLGME_02007 5.7e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
JPBFLGME_02008 1.8e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JPBFLGME_02009 4.2e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
JPBFLGME_02010 3e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
JPBFLGME_02011 4.9e-39 2.3.1.128 K acetyltransferase
JPBFLGME_02012 6.4e-29 2.3.1.128 K acetyltransferase
JPBFLGME_02013 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JPBFLGME_02014 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JPBFLGME_02015 9.1e-87 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JPBFLGME_02016 2.6e-64 WQ51_03320 S cog cog4835
JPBFLGME_02017 2.4e-44 XK27_08360 S EDD domain protein, DegV family
JPBFLGME_02018 7.8e-86 XK27_08360 T EDD domain protein, DegV family
JPBFLGME_02019 4.3e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JPBFLGME_02020 9e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JPBFLGME_02021 0.0 yfmR S abc transporter atp-binding protein
JPBFLGME_02022 3.3e-25 U response to pH
JPBFLGME_02023 3e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
JPBFLGME_02024 3.4e-208 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
JPBFLGME_02025 6.9e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
JPBFLGME_02026 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JPBFLGME_02027 1.6e-76 K DNA-binding transcription factor activity
JPBFLGME_02028 0.0 lmrA1 V abc transporter atp-binding protein
JPBFLGME_02029 0.0 lmrA2 V abc transporter atp-binding protein
JPBFLGME_02030 1.1e-49 K Acetyltransferase (GNAT) family
JPBFLGME_02031 2.7e-27 2.7.6.5 S Region found in RelA / SpoT proteins
JPBFLGME_02032 2.6e-28 2.7.6.5 S Region found in RelA / SpoT proteins
JPBFLGME_02033 7.9e-32 T response regulator
JPBFLGME_02034 2.8e-28 T response regulator
JPBFLGME_02036 1.1e-13 sptS 2.7.13.3 T Histidine kinase
JPBFLGME_02037 4.3e-107 sptS 2.7.13.3 T Histidine kinase
JPBFLGME_02038 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JPBFLGME_02039 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JPBFLGME_02040 7e-161 cvfB S Protein conserved in bacteria
JPBFLGME_02041 7.4e-35 yozE S Belongs to the UPF0346 family
JPBFLGME_02042 4.3e-120 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
JPBFLGME_02043 2.6e-61 rlpA M LysM domain protein
JPBFLGME_02044 2.3e-190 phoH T phosphate starvation-inducible protein PhoH
JPBFLGME_02048 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JPBFLGME_02049 8.3e-165 K transcriptional regulator (lysR family)
JPBFLGME_02050 1.4e-186 coiA 3.6.4.12 S Competence protein
JPBFLGME_02051 0.0 pepF E oligoendopeptidase F
JPBFLGME_02052 7.1e-127 yrrM 2.1.1.104 S O-Methyltransferase
JPBFLGME_02053 3.9e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
JPBFLGME_02054 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JPBFLGME_02055 2.5e-146 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
JPBFLGME_02056 1.9e-39 3.4.17.14, 3.5.1.28 NU amidase activity
JPBFLGME_02057 1.3e-30 3.4.17.14, 3.5.1.28 NU amidase activity
JPBFLGME_02058 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JPBFLGME_02059 8.5e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
JPBFLGME_02060 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JPBFLGME_02061 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JPBFLGME_02062 1.3e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
JPBFLGME_02063 4.5e-208 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JPBFLGME_02064 3.6e-128 yxkH G deacetylase
JPBFLGME_02065 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
JPBFLGME_02066 2.1e-149 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JPBFLGME_02067 1e-151 rarD S Transporter
JPBFLGME_02068 2.6e-16 T peptidase
JPBFLGME_02069 8.9e-14 coiA 3.6.4.12 S Competence protein
JPBFLGME_02070 2.3e-99 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JPBFLGME_02071 1.1e-96 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
JPBFLGME_02072 2.5e-16 endA F DNA/RNA non-specific endonuclease
JPBFLGME_02073 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JPBFLGME_02074 1.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JPBFLGME_02075 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
JPBFLGME_02076 2.3e-76 atpF C ATP synthase F(0) sector subunit b
JPBFLGME_02077 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JPBFLGME_02078 2.5e-278 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JPBFLGME_02079 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JPBFLGME_02080 3.9e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JPBFLGME_02081 2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JPBFLGME_02082 9.8e-228 ftsW D Belongs to the SEDS family
JPBFLGME_02083 3.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JPBFLGME_02084 3.4e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JPBFLGME_02085 3.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JPBFLGME_02086 1.1e-156 holB 2.7.7.7 L dna polymerase iii
JPBFLGME_02087 8e-135 yaaT S stage 0 sporulation protein
JPBFLGME_02088 2.8e-54 yabA L Involved in initiation control of chromosome replication
JPBFLGME_02089 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JPBFLGME_02090 2.9e-23 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)