ORF_ID e_value Gene_name EC_number CAZy COGs Description
NICGDBAB_00012 5.3e-11
NICGDBAB_00018 3.6e-138 mreC M Involved in formation and maintenance of cell shape
NICGDBAB_00019 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NICGDBAB_00020 2e-96 usp 3.5.1.28 CBM50 S CHAP domain
NICGDBAB_00021 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NICGDBAB_00022 7.3e-26
NICGDBAB_00023 3.6e-216 araT 2.6.1.1 E Aminotransferase
NICGDBAB_00024 1e-142 recO L Involved in DNA repair and RecF pathway recombination
NICGDBAB_00025 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NICGDBAB_00026 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NICGDBAB_00027 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NICGDBAB_00028 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NICGDBAB_00029 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NICGDBAB_00030 8e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NICGDBAB_00031 5.2e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NICGDBAB_00032 2.4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NICGDBAB_00033 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NICGDBAB_00034 4.2e-62 manO S protein conserved in bacteria
NICGDBAB_00035 1.8e-167 manN G PTS system mannose fructose sorbose family IID component
NICGDBAB_00036 3.9e-116 manM G pts system
NICGDBAB_00037 2.4e-173 manL 2.7.1.191 G pts system
NICGDBAB_00038 4.9e-139 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NICGDBAB_00039 5.6e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NICGDBAB_00040 3e-241 pbuO S permease
NICGDBAB_00041 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NICGDBAB_00042 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
NICGDBAB_00043 1.5e-217 brpA K Transcriptional
NICGDBAB_00044 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
NICGDBAB_00045 3.1e-212 nusA K Participates in both transcription termination and antitermination
NICGDBAB_00046 3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NICGDBAB_00047 1.4e-41 ylxQ J ribosomal protein
NICGDBAB_00048 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NICGDBAB_00049 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NICGDBAB_00050 1.8e-45 yvdD 3.2.2.10 S Belongs to the LOG family
NICGDBAB_00052 4.5e-233 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NICGDBAB_00053 7.9e-274 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NICGDBAB_00054 1e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NICGDBAB_00055 1.9e-90 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NICGDBAB_00056 2.2e-199 metB 2.5.1.48, 4.4.1.8 E cystathionine
NICGDBAB_00057 2.8e-221 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NICGDBAB_00058 8e-10 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
NICGDBAB_00059 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NICGDBAB_00060 8.3e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NICGDBAB_00061 8.3e-73 ylbF S Belongs to the UPF0342 family
NICGDBAB_00062 7.1e-46 ylbG S UPF0298 protein
NICGDBAB_00063 3.5e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NICGDBAB_00064 2.1e-144 livH E Belongs to the binding-protein-dependent transport system permease family
NICGDBAB_00065 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
NICGDBAB_00066 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NICGDBAB_00067 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NICGDBAB_00068 1e-39 acuB S CBS domain
NICGDBAB_00069 9.3e-42 acuB S IMP dehydrogenase activity
NICGDBAB_00070 1.1e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NICGDBAB_00071 6.3e-111 yvyE 3.4.13.9 S YigZ family
NICGDBAB_00072 2e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NICGDBAB_00073 4.9e-122 comFC S Competence protein
NICGDBAB_00074 2.4e-90 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NICGDBAB_00075 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
NICGDBAB_00076 7.2e-117 S Domain of unknown function (DUF1803)
NICGDBAB_00077 7.8e-102 ygaC J Belongs to the UPF0374 family
NICGDBAB_00078 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
NICGDBAB_00079 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NICGDBAB_00080 6.7e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
NICGDBAB_00081 2e-255 lysC 2.7.2.4 E Belongs to the aspartokinase family
NICGDBAB_00082 2.8e-114 S Haloacid dehalogenase-like hydrolase
NICGDBAB_00083 9e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NICGDBAB_00084 5.2e-72 marR K Transcriptional regulator, MarR family
NICGDBAB_00085 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NICGDBAB_00086 2.6e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NICGDBAB_00087 1.3e-171 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NICGDBAB_00088 1.9e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NICGDBAB_00089 1.6e-126 IQ reductase
NICGDBAB_00090 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NICGDBAB_00091 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NICGDBAB_00092 4.3e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NICGDBAB_00093 1.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NICGDBAB_00094 1.1e-158 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NICGDBAB_00095 1.5e-138 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NICGDBAB_00096 2.3e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NICGDBAB_00097 1.3e-205 rny D Endoribonuclease that initiates mRNA decay
NICGDBAB_00098 5.2e-84 L Transposase
NICGDBAB_00099 1.2e-121 fruR K transcriptional
NICGDBAB_00100 4.9e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NICGDBAB_00101 0.0 fruA 2.7.1.202 G phosphotransferase system
NICGDBAB_00102 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NICGDBAB_00103 2.6e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NICGDBAB_00105 5.7e-211 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NICGDBAB_00106 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NICGDBAB_00107 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NICGDBAB_00108 1e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NICGDBAB_00109 4.9e-39 2.3.1.128 K acetyltransferase
NICGDBAB_00110 6.4e-29 2.3.1.128 K acetyltransferase
NICGDBAB_00111 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NICGDBAB_00112 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NICGDBAB_00113 1.5e-121 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NICGDBAB_00114 2.6e-64 WQ51_03320 S cog cog4835
NICGDBAB_00115 4.4e-09 XK27_08360 S EDD domain protein, DegV family
NICGDBAB_00116 2.2e-120 XK27_08360 S EDD domain protein, DegV family
NICGDBAB_00117 1.1e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NICGDBAB_00118 2.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NICGDBAB_00119 0.0 yfmR S abc transporter atp-binding protein
NICGDBAB_00120 3.3e-25 U response to pH
NICGDBAB_00121 3e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NICGDBAB_00122 1.8e-195 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NICGDBAB_00123 2e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NICGDBAB_00124 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NICGDBAB_00125 1.6e-76 K DNA-binding transcription factor activity
NICGDBAB_00126 0.0 lmrA1 V abc transporter atp-binding protein
NICGDBAB_00127 0.0 lmrA2 V abc transporter atp-binding protein
NICGDBAB_00128 1.4e-45 K Acetyltransferase (GNAT) family
NICGDBAB_00129 4.5e-77 sptS 2.7.13.3 T Histidine kinase
NICGDBAB_00130 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NICGDBAB_00131 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NICGDBAB_00132 7e-161 cvfB S Protein conserved in bacteria
NICGDBAB_00133 7.4e-35 yozE S Belongs to the UPF0346 family
NICGDBAB_00134 5.9e-117 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
NICGDBAB_00135 6.6e-60 rlpA M LysM domain protein
NICGDBAB_00136 1e-190 phoH T phosphate starvation-inducible protein PhoH
NICGDBAB_00140 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NICGDBAB_00141 9.2e-164 K transcriptional regulator (lysR family)
NICGDBAB_00142 1.4e-186 coiA 3.6.4.12 S Competence protein
NICGDBAB_00143 0.0 pepF E oligoendopeptidase F
NICGDBAB_00144 7.1e-127 yrrM 2.1.1.104 S O-Methyltransferase
NICGDBAB_00145 2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NICGDBAB_00146 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NICGDBAB_00147 2.5e-146 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NICGDBAB_00148 3.4e-41 3.4.17.14, 3.5.1.28 NU amidase activity
NICGDBAB_00149 1.3e-30 3.4.17.14, 3.5.1.28 NU amidase activity
NICGDBAB_00150 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NICGDBAB_00151 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NICGDBAB_00152 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NICGDBAB_00153 2.6e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NICGDBAB_00154 1.2e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NICGDBAB_00155 5.3e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NICGDBAB_00156 9.4e-129 yxkH G deacetylase
NICGDBAB_00157 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NICGDBAB_00158 4.2e-150 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NICGDBAB_00159 1e-151 rarD S Transporter
NICGDBAB_00160 2.6e-16 T peptidase
NICGDBAB_00161 8.9e-14 coiA 3.6.4.12 S Competence protein
NICGDBAB_00162 8.3e-105 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NICGDBAB_00163 8.1e-69 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NICGDBAB_00164 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NICGDBAB_00165 2.4e-180 femA 2.3.2.10, 2.3.2.16 V FemAB family
NICGDBAB_00166 1.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NICGDBAB_00167 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
NICGDBAB_00168 2.3e-76 atpF C ATP synthase F(0) sector subunit b
NICGDBAB_00169 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NICGDBAB_00170 2.5e-278 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NICGDBAB_00171 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NICGDBAB_00172 6.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NICGDBAB_00173 2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NICGDBAB_00174 7.5e-228 ftsW D Belongs to the SEDS family
NICGDBAB_00175 3.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NICGDBAB_00176 3.4e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NICGDBAB_00177 3.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NICGDBAB_00178 1.1e-156 holB 2.7.7.7 L dna polymerase iii
NICGDBAB_00179 8e-135 yaaT S stage 0 sporulation protein
NICGDBAB_00180 9.5e-55 yabA L Involved in initiation control of chromosome replication
NICGDBAB_00181 5.9e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NICGDBAB_00182 3.4e-24 L Transposase
NICGDBAB_00183 1.1e-231 amt P Ammonium Transporter
NICGDBAB_00184 1.2e-52 glnB K Belongs to the P(II) protein family
NICGDBAB_00185 1.3e-103 mur1 NU mannosyl-glycoprotein
NICGDBAB_00186 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NICGDBAB_00187 1.2e-92 nptA P COG1283 Na phosphate symporter
NICGDBAB_00188 3e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NICGDBAB_00189 4.9e-51
NICGDBAB_00190 2.2e-25
NICGDBAB_00191 3.9e-60
NICGDBAB_00192 5.2e-62 S membrane
NICGDBAB_00193 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NICGDBAB_00194 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NICGDBAB_00195 4.5e-39 ynzC S UPF0291 protein
NICGDBAB_00196 2.6e-250 cycA E permease
NICGDBAB_00197 1.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
NICGDBAB_00198 7.4e-25 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
NICGDBAB_00199 1.2e-43 pts33BCA G pts system
NICGDBAB_00200 6e-182 pts33BCA G pts system
NICGDBAB_00201 7.8e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NICGDBAB_00206 1.5e-166 fhuR K transcriptional regulator (lysR family)
NICGDBAB_00207 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NICGDBAB_00208 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NICGDBAB_00209 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NICGDBAB_00210 4.9e-227 pyrP F uracil Permease
NICGDBAB_00211 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NICGDBAB_00212 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NICGDBAB_00213 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NICGDBAB_00214 3.9e-123 2.1.1.223 S Putative SAM-dependent methyltransferase
NICGDBAB_00215 4.2e-175 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NICGDBAB_00216 3.7e-120 macB V ABC transporter, ATP-binding protein
NICGDBAB_00217 7.1e-212 V permease protein
NICGDBAB_00218 0.0 L SNF2 family N-terminal domain
NICGDBAB_00219 6.9e-71 S Domain of unknown function (DUF4391)
NICGDBAB_00221 2.5e-218 mod 2.1.1.72 L Adenine specific DNA methylase Mod
NICGDBAB_00223 0.0 res 3.1.21.5 L restriction endonuclease
NICGDBAB_00224 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NICGDBAB_00225 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NICGDBAB_00226 2.8e-117 L Transposase
NICGDBAB_00227 8.5e-22 L Transposase for ISSha1
NICGDBAB_00228 2.9e-48 U response to pH
NICGDBAB_00229 6.5e-108 L Transposase
NICGDBAB_00230 1.2e-112 L Transposase
NICGDBAB_00231 1.6e-18 L Integrase core domain
NICGDBAB_00232 9.4e-75 devA 3.6.3.25 V abc transporter atp-binding protein
NICGDBAB_00233 2.8e-164 hrtB V MacB-like periplasmic core domain
NICGDBAB_00236 3e-92 S MucBP domain
NICGDBAB_00237 5.9e-51 M YSIRK type signal peptide
NICGDBAB_00238 3.7e-114 L Transposase
NICGDBAB_00239 1.5e-233 L Belongs to the 'phage' integrase family
NICGDBAB_00240 5.9e-31 S DNA binding domain, excisionase family
NICGDBAB_00241 2e-149 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NICGDBAB_00242 1.8e-107 abiGI K Transcriptional regulator, AbiEi antitoxin
NICGDBAB_00243 9.6e-179 S pathogenesis
NICGDBAB_00244 1.1e-07
NICGDBAB_00245 1.1e-267
NICGDBAB_00246 0.0 yddE S AAA-like domain
NICGDBAB_00247 6.6e-72 S TcpE family
NICGDBAB_00248 7.2e-25
NICGDBAB_00249 4.2e-85 S Conjugative transposon protein TcpC
NICGDBAB_00250 5.1e-72
NICGDBAB_00251 4.2e-28
NICGDBAB_00252 2.8e-235 K Replication initiation factor
NICGDBAB_00253 1.7e-142 M the current gene model (or a revised gene model) may contain a
NICGDBAB_00255 0.0 mdlB V abc transporter atp-binding protein
NICGDBAB_00256 0.0 lmrA V abc transporter atp-binding protein
NICGDBAB_00257 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NICGDBAB_00258 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NICGDBAB_00259 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NICGDBAB_00260 2.1e-131 rr02 KT response regulator
NICGDBAB_00261 9.7e-83 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NICGDBAB_00262 1.7e-107 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NICGDBAB_00263 4.8e-168 V ABC transporter
NICGDBAB_00264 5.4e-122 sagI S ABC-2 type transporter
NICGDBAB_00265 6.5e-195 yceA S Belongs to the UPF0176 family
NICGDBAB_00266 1e-27 XK27_00085 K Transcriptional
NICGDBAB_00267 2.7e-24
NICGDBAB_00268 8.2e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
NICGDBAB_00269 1.9e-113 S VIT family
NICGDBAB_00270 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NICGDBAB_00271 7e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NICGDBAB_00272 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
NICGDBAB_00273 9.1e-48 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NICGDBAB_00274 2.2e-246 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NICGDBAB_00275 8.8e-104 GBS0088 J protein conserved in bacteria
NICGDBAB_00276 1.4e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NICGDBAB_00277 4.1e-170 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NICGDBAB_00278 3.1e-176 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
NICGDBAB_00279 1.1e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NICGDBAB_00280 1.8e-251 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NICGDBAB_00281 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NICGDBAB_00282 2.5e-21
NICGDBAB_00283 1.7e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NICGDBAB_00285 3e-29 U protein secretion
NICGDBAB_00286 5.1e-49 U protein secretion
NICGDBAB_00287 2.5e-08 M Pilin isopeptide linkage domain protein
NICGDBAB_00288 7.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NICGDBAB_00289 1.5e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NICGDBAB_00290 1.6e-19 XK27_13030
NICGDBAB_00291 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NICGDBAB_00292 1.1e-167 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NICGDBAB_00293 9.8e-163 S Protein of unknown function (DUF3114)
NICGDBAB_00294 1.6e-22 S Protein of unknown function (DUF3114)
NICGDBAB_00295 4.7e-120 yqfA K protein, Hemolysin III
NICGDBAB_00296 1.6e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NICGDBAB_00297 2.9e-218 mvaS 2.3.3.10 I synthase
NICGDBAB_00298 1.9e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NICGDBAB_00299 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NICGDBAB_00300 9.7e-22
NICGDBAB_00301 3.7e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NICGDBAB_00302 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NICGDBAB_00303 9.2e-248 mmuP E amino acid
NICGDBAB_00304 3.4e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NICGDBAB_00305 1.4e-29 S Domain of unknown function (DUF1912)
NICGDBAB_00306 8.3e-15 L Helix-hairpin-helix DNA-binding motif class 1
NICGDBAB_00307 1.6e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NICGDBAB_00308 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NICGDBAB_00309 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NICGDBAB_00310 3.4e-199 ilvE 2.6.1.42 E Aminotransferase
NICGDBAB_00311 1.1e-15 S Protein of unknown function (DUF2969)
NICGDBAB_00314 1.3e-202 rpsA 1.17.7.4 J ribosomal protein S1
NICGDBAB_00317 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
NICGDBAB_00318 6.1e-70 M Pfam SNARE associated Golgi protein
NICGDBAB_00319 9.8e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
NICGDBAB_00320 3e-51 S oxidoreductase
NICGDBAB_00321 1.4e-54 S oxidoreductase
NICGDBAB_00322 2.4e-47 XK27_09445 S Domain of unknown function (DUF1827)
NICGDBAB_00323 5.7e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NICGDBAB_00324 0.0 clpE O Belongs to the ClpA ClpB family
NICGDBAB_00325 3.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NICGDBAB_00326 1.3e-34 ykuJ S protein conserved in bacteria
NICGDBAB_00327 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NICGDBAB_00328 1.1e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
NICGDBAB_00329 1.2e-77 feoA P FeoA domain protein
NICGDBAB_00330 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NICGDBAB_00331 1.5e-07
NICGDBAB_00332 6.5e-34 yugF I carboxylic ester hydrolase activity
NICGDBAB_00333 1.5e-23 I Alpha/beta hydrolase family
NICGDBAB_00334 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NICGDBAB_00335 3.9e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NICGDBAB_00336 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NICGDBAB_00337 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NICGDBAB_00338 5.8e-64 licT K transcriptional antiterminator
NICGDBAB_00339 6.8e-53 licT K transcriptional antiterminator
NICGDBAB_00340 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NICGDBAB_00341 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NICGDBAB_00342 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NICGDBAB_00343 5.5e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NICGDBAB_00344 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NICGDBAB_00345 1.6e-219 mdtG EGP Major facilitator Superfamily
NICGDBAB_00346 2.6e-33 secG U Preprotein translocase subunit SecG
NICGDBAB_00347 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NICGDBAB_00348 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NICGDBAB_00349 2.1e-276 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NICGDBAB_00350 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NICGDBAB_00351 2.7e-210 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NICGDBAB_00352 3.7e-182 ccpA K Catabolite control protein A
NICGDBAB_00353 5.2e-27 yyaQ S YjbR
NICGDBAB_00354 2.9e-111 yyaQ S YjbR
NICGDBAB_00355 2.9e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NICGDBAB_00356 1e-78 yueI S Protein of unknown function (DUF1694)
NICGDBAB_00357 8.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NICGDBAB_00358 1.3e-24 WQ51_00785
NICGDBAB_00359 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NICGDBAB_00360 9e-220 ywbD 2.1.1.191 J Methyltransferase
NICGDBAB_00361 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NICGDBAB_00362 1.5e-160 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NICGDBAB_00363 2.9e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NICGDBAB_00364 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NICGDBAB_00365 1.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NICGDBAB_00366 3.2e-53 yheA S Belongs to the UPF0342 family
NICGDBAB_00367 1.5e-172 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NICGDBAB_00368 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NICGDBAB_00369 2.5e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NICGDBAB_00370 2.5e-152 pheA 4.2.1.51 E Prephenate dehydratase
NICGDBAB_00371 2e-237 msrR K Transcriptional regulator
NICGDBAB_00372 1.9e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
NICGDBAB_00373 1.3e-201 I acyl-CoA dehydrogenase
NICGDBAB_00374 4.5e-97 mip S hydroperoxide reductase activity
NICGDBAB_00375 3e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NICGDBAB_00376 6.2e-46 J Acetyltransferase (GNAT) domain
NICGDBAB_00377 8.4e-35 J Acetyltransferase (GNAT) domain
NICGDBAB_00378 5.7e-95
NICGDBAB_00379 3.2e-66 L COG2801 Transposase and inactivated derivatives
NICGDBAB_00380 2.4e-71 L COG2801 Transposase and inactivated derivatives
NICGDBAB_00381 8.9e-11
NICGDBAB_00383 7.8e-59 S Protein of unknown function (DUF1722)
NICGDBAB_00384 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
NICGDBAB_00386 2.4e-33
NICGDBAB_00387 1.7e-26 S CAAX protease self-immunity
NICGDBAB_00388 1e-30 S CAAX protease self-immunity
NICGDBAB_00389 1.9e-27 estA E GDSL-like Lipase/Acylhydrolase
NICGDBAB_00390 2.1e-95
NICGDBAB_00391 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NICGDBAB_00392 2.5e-46 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NICGDBAB_00393 4e-101 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NICGDBAB_00394 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NICGDBAB_00395 3.3e-197 S CRISPR-associated protein Csn2 subfamily St
NICGDBAB_00396 2.4e-147 ycgQ S TIGR03943 family
NICGDBAB_00397 1.3e-154 XK27_03015 S permease
NICGDBAB_00399 0.0 yhgF K Transcriptional accessory protein
NICGDBAB_00400 9.9e-42 pspC KT PspC domain
NICGDBAB_00401 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NICGDBAB_00402 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NICGDBAB_00404 5.5e-69 ytxH S General stress protein
NICGDBAB_00406 2e-177 yegQ O Peptidase U32
NICGDBAB_00407 3.4e-252 yegQ O Peptidase U32
NICGDBAB_00408 2.1e-86 bioY S biotin synthase
NICGDBAB_00410 1.1e-33 XK27_12190 S protein conserved in bacteria
NICGDBAB_00411 5.1e-235 mntH P H( )-stimulated, divalent metal cation uptake system
NICGDBAB_00413 4.2e-43
NICGDBAB_00414 3.2e-145 E IrrE N-terminal-like domain
NICGDBAB_00415 1.4e-119 K Peptidase S24-like
NICGDBAB_00416 9.4e-256 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NICGDBAB_00417 2.4e-46
NICGDBAB_00418 7.1e-44
NICGDBAB_00419 0.0 L helicase
NICGDBAB_00420 0.0 L AAA ATPase domain
NICGDBAB_00421 0.0 3.6.4.12 L DNA helicase
NICGDBAB_00422 5.6e-283 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NICGDBAB_00423 1e-13 M LysM domain
NICGDBAB_00424 2.5e-44 M LysM domain
NICGDBAB_00425 2.5e-55 M LysM domain
NICGDBAB_00426 1.2e-16
NICGDBAB_00427 1.2e-171 S hydrolase
NICGDBAB_00428 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
NICGDBAB_00429 3e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NICGDBAB_00430 2e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
NICGDBAB_00431 2.7e-27 P Hemerythrin HHE cation binding domain protein
NICGDBAB_00432 4.8e-111 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NICGDBAB_00433 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
NICGDBAB_00434 2.7e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NICGDBAB_00435 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NICGDBAB_00436 8.7e-75 S Protein of unknown function (DUF1524)
NICGDBAB_00437 4.4e-105 3.1.21.3 V Type I restriction modification DNA specificity domain
NICGDBAB_00438 0.0 S KAP family P-loop domain
NICGDBAB_00439 1.2e-135 S Protein conserved in bacteria
NICGDBAB_00440 8.1e-304 hsdM 2.1.1.72 V type I restriction-modification system
NICGDBAB_00441 5.9e-22 S PD-(D/E)XK nuclease family transposase
NICGDBAB_00442 1.6e-56 spd F DNA RNA non-specific endonuclease
NICGDBAB_00443 1.1e-88 spd F DNA RNA non-specific endonuclease
NICGDBAB_00444 1.2e-89 lemA S LemA family
NICGDBAB_00445 3.8e-133 htpX O Belongs to the peptidase M48B family
NICGDBAB_00446 4.2e-75 S Psort location CytoplasmicMembrane, score
NICGDBAB_00447 6.2e-56 S Domain of unknown function (DUF4430)
NICGDBAB_00448 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NICGDBAB_00449 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
NICGDBAB_00450 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NICGDBAB_00451 1.3e-188 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NICGDBAB_00452 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NICGDBAB_00453 3.2e-92 dps P Belongs to the Dps family
NICGDBAB_00454 4.4e-79 perR P Belongs to the Fur family
NICGDBAB_00455 1.9e-27 yqgQ S protein conserved in bacteria
NICGDBAB_00456 7.8e-177 glk 2.7.1.2 G Glucokinase
NICGDBAB_00457 0.0 typA T GTP-binding protein TypA
NICGDBAB_00458 2.8e-07 S Protein of unknown function (DUF3165)
NICGDBAB_00459 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NICGDBAB_00460 3.9e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NICGDBAB_00461 8.2e-170 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NICGDBAB_00462 2.3e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NICGDBAB_00463 2.7e-236 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NICGDBAB_00464 5.1e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NICGDBAB_00465 1.4e-96 sepF D cell septum assembly
NICGDBAB_00466 2e-34 yggT D integral membrane protein
NICGDBAB_00467 8e-143 ylmH T S4 RNA-binding domain
NICGDBAB_00468 3.3e-134 divIVA D Cell division protein DivIVA
NICGDBAB_00469 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NICGDBAB_00470 1.1e-228 mntH P Mn2 and Fe2 transporters of the NRAMP family
NICGDBAB_00471 2e-45 rpmE2 J 50S ribosomal protein L31
NICGDBAB_00472 1.2e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NICGDBAB_00473 6.5e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NICGDBAB_00474 4.3e-79 gst O Glutathione S-transferase
NICGDBAB_00475 5.2e-65 gst O Glutathione S-transferase
NICGDBAB_00476 6.7e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NICGDBAB_00477 3.5e-111 tdk 2.7.1.21 F thymidine kinase
NICGDBAB_00478 1.8e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NICGDBAB_00479 6.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NICGDBAB_00480 2.5e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NICGDBAB_00481 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NICGDBAB_00482 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
NICGDBAB_00483 1.9e-101 pvaA M lytic transglycosylase activity
NICGDBAB_00484 0.0 yfiB1 V abc transporter atp-binding protein
NICGDBAB_00485 0.0 XK27_10035 V abc transporter atp-binding protein
NICGDBAB_00486 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
NICGDBAB_00487 1.6e-296 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICGDBAB_00488 3.9e-237 dltB M Membrane protein involved in D-alanine export
NICGDBAB_00489 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICGDBAB_00490 1.8e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NICGDBAB_00491 6e-46 L transposase activity
NICGDBAB_00492 0.0 3.6.3.8 P cation transport ATPase
NICGDBAB_00493 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NICGDBAB_00495 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NICGDBAB_00496 3.6e-165 metF 1.5.1.20 C reductase
NICGDBAB_00497 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NICGDBAB_00498 1.1e-93 panT S ECF transporter, substrate-specific component
NICGDBAB_00499 1.4e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NICGDBAB_00500 5.2e-119 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NICGDBAB_00501 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NICGDBAB_00502 1.2e-118 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICGDBAB_00503 1e-29 T PhoQ Sensor
NICGDBAB_00504 4.1e-43 T PhoQ Sensor
NICGDBAB_00505 1.4e-119 T PhoQ Sensor
NICGDBAB_00506 6.4e-159 S CHAP domain
NICGDBAB_00507 2e-241 purD 6.3.4.13 F Belongs to the GARS family
NICGDBAB_00508 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NICGDBAB_00509 8.5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NICGDBAB_00510 3.2e-46 1.1.1.169 H Ketopantoate reductase
NICGDBAB_00511 2.1e-85 1.1.1.169 H Ketopantoate reductase
NICGDBAB_00512 6.6e-34
NICGDBAB_00513 6.6e-136 J Domain of unknown function (DUF4041)
NICGDBAB_00515 3.3e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NICGDBAB_00516 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NICGDBAB_00517 2.2e-210 sip L Belongs to the 'phage' integrase family
NICGDBAB_00518 8e-22 xre K Cro/C1-type HTH DNA-binding domain
NICGDBAB_00519 1.4e-19 K Cro/C1-type HTH DNA-binding domain
NICGDBAB_00523 1.2e-14
NICGDBAB_00524 3.1e-22
NICGDBAB_00525 4.8e-125 KL Phage plasmid primase P4 family
NICGDBAB_00526 1.2e-66 S Virulence-associated protein E
NICGDBAB_00529 9.6e-26
NICGDBAB_00530 2.4e-19 L Belongs to the 'phage' integrase family
NICGDBAB_00532 8.2e-70 argR K Regulates arginine biosynthesis genes
NICGDBAB_00533 3.9e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NICGDBAB_00534 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NICGDBAB_00535 2.3e-78 S Protein of unknown function (DUF3021)
NICGDBAB_00536 5.4e-69 K LytTr DNA-binding domain
NICGDBAB_00538 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NICGDBAB_00540 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NICGDBAB_00541 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NICGDBAB_00542 2.9e-232 cinA 3.5.1.42 S Belongs to the CinA family
NICGDBAB_00543 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NICGDBAB_00544 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
NICGDBAB_00545 1.1e-13 L Transposase
NICGDBAB_00546 1.3e-29 rpsT J rRNA binding
NICGDBAB_00547 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
NICGDBAB_00548 3.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
NICGDBAB_00549 2.3e-26 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NICGDBAB_00550 3e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
NICGDBAB_00551 6.1e-94 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NICGDBAB_00552 2.9e-30 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NICGDBAB_00553 9.9e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NICGDBAB_00554 3.8e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NICGDBAB_00555 5.8e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NICGDBAB_00556 5.4e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NICGDBAB_00557 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
NICGDBAB_00558 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
NICGDBAB_00559 9.8e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NICGDBAB_00560 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NICGDBAB_00561 3.1e-81 ypmB S Protein conserved in bacteria
NICGDBAB_00562 2.3e-215 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NICGDBAB_00563 2.3e-259 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NICGDBAB_00564 3.7e-19
NICGDBAB_00565 2.1e-200 pmrB EGP Major facilitator Superfamily
NICGDBAB_00566 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NICGDBAB_00567 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NICGDBAB_00568 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NICGDBAB_00569 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NICGDBAB_00570 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NICGDBAB_00571 3.8e-19 D nuclear chromosome segregation
NICGDBAB_00572 5.9e-135 yejC S cyclic nucleotide-binding protein
NICGDBAB_00573 4.5e-163 rapZ S Displays ATPase and GTPase activities
NICGDBAB_00574 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NICGDBAB_00575 1.9e-161 whiA K May be required for sporulation
NICGDBAB_00576 9.7e-98 pepD E Dipeptidase
NICGDBAB_00577 2.6e-44 pepD E Dipeptidase
NICGDBAB_00578 1.5e-75 tspO T TspO/MBR family
NICGDBAB_00579 2.6e-59 S Uncharacterised lipoprotein family
NICGDBAB_00580 7.1e-28 L transposase activity
NICGDBAB_00582 9e-27
NICGDBAB_00583 9.3e-32 cspD K Cold shock protein domain
NICGDBAB_00584 8e-42 K Cold-Shock Protein
NICGDBAB_00585 0.0 copB 3.6.3.4 P COG2217 Cation transport ATPase
NICGDBAB_00586 2e-147 glcU U sugar transport
NICGDBAB_00587 2.3e-93 hsdM 2.1.1.72 V type I restriction-modification system
NICGDBAB_00588 2.6e-55 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
NICGDBAB_00589 3e-153
NICGDBAB_00590 4.9e-105 L Phage integrase family
NICGDBAB_00591 6.5e-113
NICGDBAB_00593 6.2e-58 pepD E Dipeptidase
NICGDBAB_00594 1.2e-86 XK27_10720 D peptidase activity
NICGDBAB_00595 1.2e-95 adcA P Belongs to the bacterial solute-binding protein 9 family
NICGDBAB_00596 1.1e-178 adcA P Belongs to the bacterial solute-binding protein 9 family
NICGDBAB_00597 1.7e-08
NICGDBAB_00598 1.5e-170 yeiH S Membrane
NICGDBAB_00599 1.6e-118 mur1 NU muramidase
NICGDBAB_00600 4.2e-20 L transposase activity
NICGDBAB_00601 4.5e-166 cpsY K Transcriptional regulator
NICGDBAB_00602 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NICGDBAB_00603 6.1e-57 phnA P Alkylphosphonate utilization operon protein PhnA
NICGDBAB_00604 5.3e-105 artQ P ABC transporter (Permease
NICGDBAB_00605 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
NICGDBAB_00606 1.2e-157 aatB ET ABC transporter substrate-binding protein
NICGDBAB_00607 2.1e-73 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NICGDBAB_00608 6.1e-109 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NICGDBAB_00609 2.1e-07
NICGDBAB_00610 6.6e-62 adhP 1.1.1.1 C alcohol dehydrogenase
NICGDBAB_00611 6.1e-112 adhP 1.1.1.1 C alcohol dehydrogenase
NICGDBAB_00613 3e-21
NICGDBAB_00614 0.0 res_1 3.1.21.5 S Type III restriction
NICGDBAB_00615 0.0 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
NICGDBAB_00616 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NICGDBAB_00617 2e-126 gntR1 K transcriptional
NICGDBAB_00618 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NICGDBAB_00619 2.1e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NICGDBAB_00620 9.1e-87 niaX
NICGDBAB_00621 6e-91 niaR S small molecule binding protein (contains 3H domain)
NICGDBAB_00622 8.1e-128 K DNA-binding helix-turn-helix protein
NICGDBAB_00623 1.2e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NICGDBAB_00624 1.2e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NICGDBAB_00625 4.5e-166 GK ROK family
NICGDBAB_00626 3.2e-158 dprA LU DNA protecting protein DprA
NICGDBAB_00627 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NICGDBAB_00628 3.6e-154 S TraX protein
NICGDBAB_00629 1.9e-121 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICGDBAB_00630 6.5e-249 T PhoQ Sensor
NICGDBAB_00631 9.6e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NICGDBAB_00632 1.4e-77 XK27_05470 E Methionine synthase
NICGDBAB_00633 6e-35 XK27_05470 E Methionine synthase
NICGDBAB_00634 5e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NICGDBAB_00635 4.4e-45 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NICGDBAB_00636 2.9e-92 ET Bacterial periplasmic substrate-binding proteins
NICGDBAB_00637 1.9e-100 IQ Acetoin reductase
NICGDBAB_00638 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NICGDBAB_00642 1.1e-53 K peptidyl-tyrosine sulfation
NICGDBAB_00643 2.8e-154 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NICGDBAB_00646 1.5e-212 pqqE C radical SAM domain protein
NICGDBAB_00647 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
NICGDBAB_00648 6.6e-61 EGP Major facilitator Superfamily
NICGDBAB_00649 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NICGDBAB_00650 5.9e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NICGDBAB_00651 1.7e-90 L Transposase
NICGDBAB_00652 8.2e-118 V ABC transporter (Permease
NICGDBAB_00653 2.2e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NICGDBAB_00654 1.6e-10
NICGDBAB_00655 1.2e-97 K Transcriptional regulator, TetR family
NICGDBAB_00656 3.1e-159 czcD P cation diffusion facilitator family transporter
NICGDBAB_00657 3.9e-123 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NICGDBAB_00658 2.4e-41 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NICGDBAB_00659 1e-23 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NICGDBAB_00660 8e-123 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NICGDBAB_00661 6e-08 S Hydrolases of the alpha beta superfamily
NICGDBAB_00662 1e-16 S Alpha/beta hydrolase of unknown function (DUF915)
NICGDBAB_00663 5.7e-52 S Alpha/beta hydrolase of unknown function (DUF915)
NICGDBAB_00666 8.4e-142 2.4.2.3 F Phosphorylase superfamily
NICGDBAB_00667 1.6e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NICGDBAB_00668 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
NICGDBAB_00669 4.7e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
NICGDBAB_00670 3.9e-26 dinF V drug transmembrane transporter activity
NICGDBAB_00672 3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NICGDBAB_00673 1e-147
NICGDBAB_00674 8.4e-34
NICGDBAB_00675 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
NICGDBAB_00676 3.5e-28 3.4.13.21 I Protein conserved in bacteria
NICGDBAB_00678 5.7e-118 S TraX protein
NICGDBAB_00679 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NICGDBAB_00680 3.5e-146 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NICGDBAB_00681 2.1e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NICGDBAB_00682 6.8e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NICGDBAB_00683 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NICGDBAB_00684 4.4e-68 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NICGDBAB_00685 2.2e-220 mesE M HlyD family secretion protein
NICGDBAB_00686 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NICGDBAB_00690 2.6e-46 S Enterocin A Immunity
NICGDBAB_00691 3.1e-10 blpU S hmm tigr01847
NICGDBAB_00693 3.1e-16
NICGDBAB_00694 1.2e-51
NICGDBAB_00698 7.4e-09 S Bacteriocin class II with double-glycine leader peptide
NICGDBAB_00699 6e-54
NICGDBAB_00701 4.9e-16
NICGDBAB_00702 2.3e-134 blpT
NICGDBAB_00703 2.2e-25
NICGDBAB_00704 1.2e-132 agrA KT phosphorelay signal transduction system
NICGDBAB_00705 2e-138 2.7.13.3 T protein histidine kinase activity
NICGDBAB_00708 1.8e-51 csm6 S Psort location Cytoplasmic, score
NICGDBAB_00709 7.8e-117 csm6 S Psort location Cytoplasmic, score
NICGDBAB_00710 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NICGDBAB_00711 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NICGDBAB_00713 4.5e-18 nylA 3.5.1.4 J Belongs to the amidase family
NICGDBAB_00714 2.9e-39 nylA 3.5.1.4 J Belongs to the amidase family
NICGDBAB_00715 4.2e-41 yckB ET Belongs to the bacterial solute-binding protein 3 family
NICGDBAB_00716 3.3e-44 yecS P ABC transporter (Permease
NICGDBAB_00717 9.3e-09 yecS P ABC transporter (Permease
NICGDBAB_00719 5.2e-24 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
NICGDBAB_00720 1.1e-96 yfiF3 K sequence-specific DNA binding
NICGDBAB_00721 8.8e-22 bglC K Transcriptional regulator
NICGDBAB_00722 8.6e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NICGDBAB_00723 7.6e-239 agcS E (Alanine) symporter
NICGDBAB_00724 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NICGDBAB_00725 2.3e-240 metY 2.5.1.49 E o-acetylhomoserine
NICGDBAB_00726 3.2e-133 S haloacid dehalogenase-like hydrolase
NICGDBAB_00727 3.8e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NICGDBAB_00728 3.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NICGDBAB_00729 5.7e-33 M1-755 P Hemerythrin HHE cation binding domain protein
NICGDBAB_00730 2.2e-77 XK27_04775 S hemerythrin HHE cation binding domain
NICGDBAB_00731 6.7e-78 XK27_04775 S hemerythrin HHE cation binding domain
NICGDBAB_00732 4.4e-49 XK27_04775 S hemerythrin HHE cation binding domain
NICGDBAB_00733 2.4e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NICGDBAB_00734 8.4e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NICGDBAB_00735 1e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NICGDBAB_00736 4.3e-43 yktA S Belongs to the UPF0223 family
NICGDBAB_00737 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NICGDBAB_00738 8.7e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NICGDBAB_00739 4.8e-157 pstS P phosphate
NICGDBAB_00740 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
NICGDBAB_00741 1.5e-155 pstA P phosphate transport system permease
NICGDBAB_00742 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NICGDBAB_00743 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NICGDBAB_00744 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
NICGDBAB_00745 0.0 pepN 3.4.11.2 E aminopeptidase
NICGDBAB_00746 1e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NICGDBAB_00747 7.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
NICGDBAB_00750 3.7e-09
NICGDBAB_00751 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NICGDBAB_00752 5.4e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NICGDBAB_00753 1.2e-62 malR K Transcriptional regulator
NICGDBAB_00754 3.7e-46 malR K Transcriptional regulator
NICGDBAB_00755 4.2e-17 malX G ABC transporter
NICGDBAB_00756 9.1e-168 malX G ABC transporter
NICGDBAB_00757 1.1e-202 malF P ABC transporter (Permease
NICGDBAB_00758 4.6e-25 tatA U protein secretion
NICGDBAB_00759 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NICGDBAB_00760 4.7e-302 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NICGDBAB_00761 5.6e-233 ycdB P peroxidase
NICGDBAB_00762 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
NICGDBAB_00763 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_00764 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_00765 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_00766 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_00767 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_00768 1.9e-186 3.5.1.28 M GBS Bsp-like repeat
NICGDBAB_00769 2e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NICGDBAB_00770 0.0 lpdA 1.8.1.4 C Dehydrogenase
NICGDBAB_00771 1.3e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NICGDBAB_00772 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NICGDBAB_00773 1.7e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NICGDBAB_00774 0.0 S the current gene model (or a revised gene model) may contain a frame shift
NICGDBAB_00775 5.3e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NICGDBAB_00776 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NICGDBAB_00777 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NICGDBAB_00778 2.9e-21 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NICGDBAB_00779 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
NICGDBAB_00780 4.1e-127 3.4.16.4 M Belongs to the peptidase S11 family
NICGDBAB_00781 4.6e-157 rssA S Phospholipase, patatin family
NICGDBAB_00782 1.8e-69 estA E GDSL-like protein
NICGDBAB_00783 3.4e-29 estA E Lysophospholipase L1 and related esterases
NICGDBAB_00784 4.5e-291 S unusual protein kinase
NICGDBAB_00785 4.9e-39 S granule-associated protein
NICGDBAB_00786 1.7e-106 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NICGDBAB_00787 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NICGDBAB_00788 1.6e-197 S hmm pf01594
NICGDBAB_00789 3.9e-102 G Belongs to the phosphoglycerate mutase family
NICGDBAB_00790 5.2e-82 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NICGDBAB_00791 2.2e-94 V VanZ like family
NICGDBAB_00792 6e-39 L Helix-turn-helix domain of transposase family ISL3
NICGDBAB_00793 8.5e-193 wbbI M transferase activity, transferring glycosyl groups
NICGDBAB_00794 2e-213 glf 5.4.99.9 M UDP-galactopyranose mutase
NICGDBAB_00795 8.3e-244 epsU S Polysaccharide biosynthesis protein
NICGDBAB_00796 6.3e-173
NICGDBAB_00797 6e-148 M Glycosyltransferase like family 2
NICGDBAB_00798 1.1e-122 M Glycosyltransferase, group 2 family protein
NICGDBAB_00800 5.4e-29 Z012_10770 M Domain of unknown function (DUF1919)
NICGDBAB_00801 1.9e-57 Z012_10770 M Domain of unknown function (DUF1919)
NICGDBAB_00803 1.9e-07
NICGDBAB_00808 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NICGDBAB_00809 2.8e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NICGDBAB_00810 1.6e-35 XK27_02060 S Transglycosylase associated protein
NICGDBAB_00811 4.4e-55 badR K DNA-binding transcription factor activity
NICGDBAB_00812 6e-97 S reductase
NICGDBAB_00813 1.2e-32 L Integrase core domain protein
NICGDBAB_00815 1.5e-172 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NICGDBAB_00817 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NICGDBAB_00818 1.1e-181 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NICGDBAB_00819 9.3e-83 S Putative small multi-drug export protein
NICGDBAB_00820 6.2e-76 ctsR K Belongs to the CtsR family
NICGDBAB_00821 0.0 clpC O Belongs to the ClpA ClpB family
NICGDBAB_00822 3e-71 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NICGDBAB_00823 3.9e-59 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NICGDBAB_00824 7.1e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NICGDBAB_00825 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NICGDBAB_00826 2.2e-142 S SseB protein N-terminal domain
NICGDBAB_00827 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
NICGDBAB_00828 2.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NICGDBAB_00829 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NICGDBAB_00832 2.4e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NICGDBAB_00833 4.6e-91 yacP S RNA-binding protein containing a PIN domain
NICGDBAB_00834 2.8e-154 degV S DegV family
NICGDBAB_00835 4.3e-20 K helix-turn-helix
NICGDBAB_00836 3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NICGDBAB_00837 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NICGDBAB_00838 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NICGDBAB_00839 6.7e-210 L Phage integrase family
NICGDBAB_00840 1e-33 S Helix-turn-helix domain
NICGDBAB_00841 8.4e-97 S Plasmid replication protein
NICGDBAB_00842 3.5e-38
NICGDBAB_00843 5.2e-198 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NICGDBAB_00844 1.9e-47
NICGDBAB_00846 4.3e-181 norB P Major Facilitator Superfamily
NICGDBAB_00847 3.8e-78 C nadph quinone reductase
NICGDBAB_00848 1.4e-37 K Transcriptional regulator
NICGDBAB_00849 1.4e-68 S phosphonoacetaldehyde hydrolase activity
NICGDBAB_00850 1.7e-28 pcaC 3.1.1.24, 4.1.1.44 S peroxiredoxin activity
NICGDBAB_00851 6.5e-31 ais G Phosphoglycerate mutase
NICGDBAB_00853 5.7e-211 wcoF M Glycosyltransferase, group 1 family protein
NICGDBAB_00854 6.5e-218 rgpAc GT4 M group 1 family protein
NICGDBAB_00855 1.3e-249 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NICGDBAB_00856 3.8e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
NICGDBAB_00857 1.4e-106 cps4C M biosynthesis protein
NICGDBAB_00858 5.1e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NICGDBAB_00859 2.6e-256 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NICGDBAB_00860 1.2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NICGDBAB_00861 1.7e-123 yfeJ 6.3.5.2 F glutamine amidotransferase
NICGDBAB_00862 1.1e-58 clcA_2 P chloride
NICGDBAB_00863 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NICGDBAB_00864 8.1e-41 S Protein of unknown function (DUF1697)
NICGDBAB_00865 1.2e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NICGDBAB_00866 9.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NICGDBAB_00867 4.3e-08 V Glucan-binding protein C
NICGDBAB_00868 8.8e-21 V Glucan-binding protein C
NICGDBAB_00869 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
NICGDBAB_00870 9e-275 pepV 3.5.1.18 E Dipeptidase
NICGDBAB_00871 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NICGDBAB_00872 1e-40 XK27_03610 K Gnat family
NICGDBAB_00873 7.2e-83 L Transposase
NICGDBAB_00874 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NICGDBAB_00875 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NICGDBAB_00876 5.9e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NICGDBAB_00877 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NICGDBAB_00878 2.8e-18 M LysM domain
NICGDBAB_00879 1.2e-88 ebsA S Family of unknown function (DUF5322)
NICGDBAB_00880 6.5e-229 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NICGDBAB_00881 7.1e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NICGDBAB_00882 1.1e-223 G COG0457 FOG TPR repeat
NICGDBAB_00883 8.1e-176 yubA S permease
NICGDBAB_00884 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NICGDBAB_00885 1.5e-161 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NICGDBAB_00886 5.5e-124 ftsE D cell division ATP-binding protein FtsE
NICGDBAB_00887 4.8e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NICGDBAB_00888 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NICGDBAB_00889 9.2e-183 yjjH S Calcineurin-like phosphoesterase
NICGDBAB_00890 1.7e-134 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NICGDBAB_00891 0.0 pacL 3.6.3.8 P cation transport ATPase
NICGDBAB_00892 3.4e-67 ywiB S Domain of unknown function (DUF1934)
NICGDBAB_00893 2.4e-44 XK27_00115 2.3.1.128 K acetyltransferase
NICGDBAB_00894 9.2e-147 yidA S hydrolases of the HAD superfamily
NICGDBAB_00895 3.4e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NICGDBAB_00896 3.9e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NICGDBAB_00897 5.8e-247 vicK 2.7.13.3 T Histidine kinase
NICGDBAB_00898 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICGDBAB_00899 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
NICGDBAB_00900 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NICGDBAB_00901 8e-115 gltJ P ABC transporter (Permease
NICGDBAB_00902 3.8e-111 tcyB_2 P ABC transporter (permease)
NICGDBAB_00903 1.2e-125 endA F DNA RNA non-specific endonuclease
NICGDBAB_00904 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
NICGDBAB_00905 9.4e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NICGDBAB_00907 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NICGDBAB_00908 1.3e-36 5.1.3.2 GM Psort location CytoplasmicMembrane, score
NICGDBAB_00909 6e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NICGDBAB_00910 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NICGDBAB_00911 7.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NICGDBAB_00912 2.7e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NICGDBAB_00913 3e-162 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NICGDBAB_00914 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
NICGDBAB_00916 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NICGDBAB_00917 2.1e-219 XK27_05110 P chloride
NICGDBAB_00918 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NICGDBAB_00919 1.7e-282 clcA P Chloride transporter, ClC family
NICGDBAB_00920 1e-75 fld C Flavodoxin
NICGDBAB_00921 3.3e-14 XK27_08880
NICGDBAB_00922 3e-125 XK27_08875 O Zinc-dependent metalloprotease
NICGDBAB_00923 1.1e-149 estA CE1 S Putative esterase
NICGDBAB_00924 4.3e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NICGDBAB_00925 4.4e-135 XK27_08845 S abc transporter atp-binding protein
NICGDBAB_00926 2e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NICGDBAB_00927 5.4e-173 XK27_08835 S ABC transporter substrate binding protein
NICGDBAB_00928 3.2e-17 S Domain of unknown function (DUF4649)
NICGDBAB_00929 6.9e-30 Q the current gene model (or a revised gene model) may contain a frame shift
NICGDBAB_00930 6.3e-28 Q the current gene model (or a revised gene model) may contain a frame shift
NICGDBAB_00933 8.2e-274 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NICGDBAB_00934 8.8e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NICGDBAB_00935 0.0 dnaE 2.7.7.7 L DNA polymerase
NICGDBAB_00936 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
NICGDBAB_00937 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NICGDBAB_00938 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NICGDBAB_00939 2.5e-43 ysdA L Membrane
NICGDBAB_00940 9.5e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NICGDBAB_00941 2.9e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NICGDBAB_00942 3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NICGDBAB_00943 3.3e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NICGDBAB_00945 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NICGDBAB_00946 3e-91 ypmS S Protein conserved in bacteria
NICGDBAB_00947 1.9e-86 ypmR E lipolytic protein G-D-S-L family
NICGDBAB_00948 3.8e-45 ypmR E COG2755 Lysophospholipase L1 and related esterases
NICGDBAB_00949 3.3e-147 DegV S DegV family
NICGDBAB_00950 1.4e-303 recN L May be involved in recombinational repair of damaged DNA
NICGDBAB_00951 3.7e-73 argR K Regulates arginine biosynthesis genes
NICGDBAB_00952 1.6e-157 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NICGDBAB_00953 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NICGDBAB_00954 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
NICGDBAB_00955 4.5e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NICGDBAB_00956 2.5e-07 KT response to antibiotic
NICGDBAB_00958 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NICGDBAB_00959 1.5e-124 dnaD
NICGDBAB_00960 1.3e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NICGDBAB_00961 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NICGDBAB_00962 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NICGDBAB_00963 1.5e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NICGDBAB_00964 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NICGDBAB_00965 3.9e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NICGDBAB_00966 2.7e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NICGDBAB_00967 7.3e-232 rodA D Belongs to the SEDS family
NICGDBAB_00968 2e-49 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NICGDBAB_00969 8e-60 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NICGDBAB_00970 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NICGDBAB_00971 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NICGDBAB_00972 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NICGDBAB_00973 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NICGDBAB_00974 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NICGDBAB_00975 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NICGDBAB_00976 2.8e-182 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NICGDBAB_00977 8.2e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NICGDBAB_00979 3.5e-50 L transposition
NICGDBAB_00980 1e-90 L transposase activity
NICGDBAB_00981 2e-31 XK27_08085
NICGDBAB_00982 8.4e-88 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NICGDBAB_00983 7.9e-10 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NICGDBAB_00984 5.8e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NICGDBAB_00985 5.8e-120 ylfI S tigr01906
NICGDBAB_00986 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NICGDBAB_00987 4.8e-142 fat 3.1.2.21 I Acyl-ACP thioesterase
NICGDBAB_00988 4.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
NICGDBAB_00991 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NICGDBAB_00992 2.7e-111 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NICGDBAB_00993 5.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NICGDBAB_00994 1.7e-204 yurR 1.4.5.1 E oxidoreductase
NICGDBAB_00995 1.6e-101 zupT P Mediates zinc uptake. May also transport other divalent cations
NICGDBAB_00996 7e-22 zupT P Mediates zinc uptake. May also transport other divalent cations
NICGDBAB_00997 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NICGDBAB_00998 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NICGDBAB_00999 1.3e-70 gtrA S GtrA-like protein
NICGDBAB_01000 1.3e-249 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NICGDBAB_01001 6e-169 ybbR S Protein conserved in bacteria
NICGDBAB_01002 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NICGDBAB_01003 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NICGDBAB_01004 8.7e-150 cobQ S glutamine amidotransferase
NICGDBAB_01005 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NICGDBAB_01006 3.1e-130 pip 1.11.1.10 S Alpha beta hydrolase
NICGDBAB_01008 0.0 uup S abc transporter atp-binding protein
NICGDBAB_01009 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NICGDBAB_01010 1.8e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
NICGDBAB_01011 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NICGDBAB_01012 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NICGDBAB_01013 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NICGDBAB_01014 7.9e-39 ptsH G phosphocarrier protein Hpr
NICGDBAB_01015 8.2e-221 icd 1.1.1.42 C Isocitrate dehydrogenase
NICGDBAB_01016 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NICGDBAB_01017 8.5e-34 nrdH O Glutaredoxin
NICGDBAB_01018 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NICGDBAB_01019 8.6e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NICGDBAB_01021 4.2e-71 L Transposase (IS116 IS110 IS902 family)
NICGDBAB_01022 8.8e-60 L Transposase (IS116 IS110 IS902 family)
NICGDBAB_01023 5.3e-165 ypuA S secreted protein
NICGDBAB_01024 1.5e-52 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
NICGDBAB_01025 1.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NICGDBAB_01026 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NICGDBAB_01027 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NICGDBAB_01028 3.7e-257 noxE P NADH oxidase
NICGDBAB_01029 3.6e-293 yfmM S abc transporter atp-binding protein
NICGDBAB_01030 4.8e-59 XK27_01265 S ECF-type riboflavin transporter, S component
NICGDBAB_01031 1.5e-10 XK27_01265 S ECF-type riboflavin transporter, S component
NICGDBAB_01032 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NICGDBAB_01033 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NICGDBAB_01034 2e-86 S ECF-type riboflavin transporter, S component
NICGDBAB_01036 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NICGDBAB_01037 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NICGDBAB_01039 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NICGDBAB_01040 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICGDBAB_01041 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NICGDBAB_01042 0.0 smc D Required for chromosome condensation and partitioning
NICGDBAB_01043 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NICGDBAB_01044 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NICGDBAB_01045 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NICGDBAB_01046 2.8e-93 pat 2.3.1.183 M acetyltransferase
NICGDBAB_01047 1.6e-11 L Transposase
NICGDBAB_01048 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NICGDBAB_01049 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NICGDBAB_01050 3.9e-37 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NICGDBAB_01051 1.5e-55 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NICGDBAB_01052 1.9e-60 sdaAB 4.3.1.17 E L-serine dehydratase
NICGDBAB_01053 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICGDBAB_01054 3.1e-145 desK 2.7.13.3 T Histidine kinase
NICGDBAB_01055 2.4e-36 desK 2.7.13.3 T Histidine kinase
NICGDBAB_01056 1.5e-132 yvfS V ABC-2 type transporter
NICGDBAB_01057 5.7e-158 XK27_09825 V abc transporter atp-binding protein
NICGDBAB_01060 1.5e-132 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
NICGDBAB_01061 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
NICGDBAB_01062 4.6e-42 3.6.1.55 F NUDIX domain
NICGDBAB_01064 3.7e-122 S An automated process has identified a potential problem with this gene model
NICGDBAB_01065 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
NICGDBAB_01066 1.6e-14 liaI KT membrane
NICGDBAB_01067 2.6e-30 liaI KT membrane
NICGDBAB_01068 5.1e-98 XK27_05000 S Fe-S-cluster oxidoreductase
NICGDBAB_01069 0.0 V ABC transporter (permease)
NICGDBAB_01070 5.4e-133 macB2 V ABC transporter, ATP-binding protein
NICGDBAB_01071 6.2e-166 T Histidine kinase
NICGDBAB_01072 2e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICGDBAB_01073 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NICGDBAB_01074 3.3e-69 pbuX F xanthine permease
NICGDBAB_01075 2.8e-112 pbuX F xanthine permease
NICGDBAB_01076 1.3e-246 norM V Multidrug efflux pump
NICGDBAB_01077 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NICGDBAB_01078 2.6e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
NICGDBAB_01079 1.1e-197 pcaB 4.3.2.2 F Adenylosuccinate lyase
NICGDBAB_01080 2.8e-92 yxeO 3.6.3.21 E abc transporter atp-binding protein
NICGDBAB_01081 1.4e-63 yxeN U ABC transporter, permease protein
NICGDBAB_01082 2.7e-57 yxeL K Acetyltransferase (GNAT) domain
NICGDBAB_01083 3e-115 yxeQ S MmgE/PrpD family
NICGDBAB_01084 2.1e-147 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NICGDBAB_01085 3.5e-104 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
NICGDBAB_01086 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
NICGDBAB_01087 2.3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NICGDBAB_01088 5.1e-235 brnQ E Component of the transport system for branched-chain amino acids
NICGDBAB_01089 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
NICGDBAB_01090 6.3e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
NICGDBAB_01091 9.6e-26 csbD K CsbD-like
NICGDBAB_01092 4.3e-245 yfnA E amino acid
NICGDBAB_01093 5.7e-109 XK27_02070 S nitroreductase
NICGDBAB_01094 2.7e-146 1.13.11.2 S glyoxalase
NICGDBAB_01095 4.7e-76 ywnA K Transcriptional regulator
NICGDBAB_01096 2.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
NICGDBAB_01097 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NICGDBAB_01098 1.4e-110 drgA C Nitroreductase
NICGDBAB_01099 1.6e-30 yoaK S Protein of unknown function (DUF1275)
NICGDBAB_01101 6.8e-161 yvgN C reductase
NICGDBAB_01102 2.8e-179 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NICGDBAB_01103 7.3e-283 XK27_07020 S Belongs to the UPF0371 family
NICGDBAB_01105 7e-54 K response regulator
NICGDBAB_01106 1.3e-70 S Signal peptide protein, YSIRK family
NICGDBAB_01108 1.2e-110
NICGDBAB_01109 2.4e-12 IQ PFAM AMP-dependent synthetase and ligase
NICGDBAB_01110 1.9e-69 IQ PFAM AMP-dependent synthetase and ligase
NICGDBAB_01111 3.5e-106 MA20_06410 E LysE type translocator
NICGDBAB_01112 2.2e-22 IQ PFAM AMP-dependent synthetase and ligase
NICGDBAB_01113 5.8e-109 MA20_06410 E LysE type translocator
NICGDBAB_01114 2e-17
NICGDBAB_01116 0.0 M family 8
NICGDBAB_01117 3.3e-247 G polysaccharide deacetylase
NICGDBAB_01118 9.4e-32 dhaL 2.7.1.121 G Dihydroxyacetone kinase
NICGDBAB_01119 5.4e-124 tnp L Transposase IS66 family
NICGDBAB_01120 2.5e-225 capA M Bacterial capsule synthesis protein
NICGDBAB_01121 6.1e-39 gcvR T UPF0237 protein
NICGDBAB_01122 8.7e-243 XK27_08635 S UPF0210 protein
NICGDBAB_01123 5.4e-135 ais G Phosphoglycerate mutase
NICGDBAB_01124 7.9e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NICGDBAB_01125 3.6e-100 acmA 3.2.1.17 NU amidase activity
NICGDBAB_01126 3.5e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NICGDBAB_01127 1.9e-69 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NICGDBAB_01128 8.4e-281 dnaK O Heat shock 70 kDa protein
NICGDBAB_01129 4.5e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NICGDBAB_01130 9.4e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NICGDBAB_01131 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NICGDBAB_01132 3.3e-72 hmpT S cog cog4720
NICGDBAB_01133 1e-31
NICGDBAB_01134 0.0 sbcC L ATPase involved in DNA repair
NICGDBAB_01135 7.6e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NICGDBAB_01136 0.0 lacL 3.2.1.23 G -beta-galactosidase
NICGDBAB_01137 0.0 lacS G transporter
NICGDBAB_01138 8.7e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NICGDBAB_01139 1.2e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NICGDBAB_01140 1.9e-283 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NICGDBAB_01141 1.1e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NICGDBAB_01142 3.1e-181 galR K Transcriptional regulator
NICGDBAB_01143 1.2e-08 L Integrase core domain protein
NICGDBAB_01144 6.7e-24 L transposition
NICGDBAB_01145 8.1e-258 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NICGDBAB_01146 1.2e-100 V abc transporter atp-binding protein
NICGDBAB_01147 2.1e-39 V (ABC) transporter
NICGDBAB_01148 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NICGDBAB_01150 4.1e-273 S Protein of unknown function (DUF3114)
NICGDBAB_01151 1.7e-51 2.3.1.128 K Acetyltransferase GNAT Family
NICGDBAB_01152 1.1e-196 V (ABC) transporter
NICGDBAB_01153 1.2e-157 C Arylsulfatase regulator (Fe-S oxidoreductase)
NICGDBAB_01154 1.5e-37 L transposase activity
NICGDBAB_01155 5.9e-25 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NICGDBAB_01156 2.1e-82 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_01157 1e-11 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_01158 9.9e-56 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_01159 2.9e-131 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NICGDBAB_01160 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NICGDBAB_01161 5.6e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NICGDBAB_01162 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NICGDBAB_01163 1.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NICGDBAB_01166 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NICGDBAB_01167 2.5e-173 vraS 2.7.13.3 T Histidine kinase
NICGDBAB_01168 4.5e-118 yvqF KT membrane
NICGDBAB_01169 2.9e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
NICGDBAB_01170 2.9e-131 stp 3.1.3.16 T phosphatase
NICGDBAB_01171 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NICGDBAB_01172 1e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NICGDBAB_01173 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NICGDBAB_01174 3e-45 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NICGDBAB_01175 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NICGDBAB_01176 6.7e-214 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NICGDBAB_01177 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
NICGDBAB_01178 2.1e-148 supH S overlaps another CDS with the same product name
NICGDBAB_01179 8.6e-63 yvoA_1 K Transcriptional
NICGDBAB_01180 9.8e-121 skfE V abc transporter atp-binding protein
NICGDBAB_01181 5.6e-133 V ATPase activity
NICGDBAB_01182 6.6e-40 oppF P Belongs to the ABC transporter superfamily
NICGDBAB_01183 1.4e-203 oppD P Belongs to the ABC transporter superfamily
NICGDBAB_01184 3.1e-167 amiD P ABC transporter (Permease
NICGDBAB_01185 1.1e-270 amiC P ABC transporter (Permease
NICGDBAB_01186 1.1e-150 amiA E ABC transporter, substrate-binding protein, family 5
NICGDBAB_01187 5.5e-158 amiA E ABC transporter, substrate-binding protein, family 5
NICGDBAB_01188 5e-45 oppF P Belongs to the ABC transporter superfamily
NICGDBAB_01189 1.4e-40 tatD L Hydrolase, tatd
NICGDBAB_01190 9.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
NICGDBAB_01191 3.9e-54 L PFAM Integrase catalytic region
NICGDBAB_01192 1.3e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NICGDBAB_01193 1.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NICGDBAB_01194 3.7e-151 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NICGDBAB_01195 1.4e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NICGDBAB_01196 1.5e-103 yjbK S Adenylate cyclase
NICGDBAB_01197 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NICGDBAB_01198 1.2e-205 iscS 2.8.1.7 E Cysteine desulfurase
NICGDBAB_01199 1.2e-58 XK27_04120 S Putative amino acid metabolism
NICGDBAB_01200 1.1e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NICGDBAB_01201 5.1e-130 puuD T peptidase C26
NICGDBAB_01202 2.4e-119 radC E Belongs to the UPF0758 family
NICGDBAB_01203 1.1e-181
NICGDBAB_01204 1.1e-98
NICGDBAB_01205 0.0 rgpF M Rhamnan synthesis protein F
NICGDBAB_01206 3.1e-195 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NICGDBAB_01207 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NICGDBAB_01208 1.4e-142 rgpC GM Transport permease protein
NICGDBAB_01209 2.4e-178 rgpB GT2 M Glycosyltransferase, group 2 family protein
NICGDBAB_01210 4.5e-224 rgpA GT4 M Domain of unknown function (DUF1972)
NICGDBAB_01211 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NICGDBAB_01212 7.8e-244
NICGDBAB_01213 6.3e-168 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NICGDBAB_01214 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NICGDBAB_01215 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NICGDBAB_01216 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NICGDBAB_01217 4.3e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NICGDBAB_01218 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NICGDBAB_01219 4.2e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
NICGDBAB_01220 4e-201 arcT 2.6.1.1 E Aminotransferase
NICGDBAB_01221 2.5e-136 ET ABC transporter
NICGDBAB_01222 7.7e-141 ET Belongs to the bacterial solute-binding protein 3 family
NICGDBAB_01223 2.9e-84 mutT 3.6.1.55 F Nudix family
NICGDBAB_01224 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NICGDBAB_01226 4.3e-82 S CAAX amino terminal protease family protein
NICGDBAB_01227 4e-33 S CAAX amino terminal protease family protein
NICGDBAB_01228 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NICGDBAB_01229 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
NICGDBAB_01230 1.1e-16 XK27_00735
NICGDBAB_01231 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NICGDBAB_01232 3.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NICGDBAB_01235 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
NICGDBAB_01236 1.4e-50 ycaO O OsmC-like protein
NICGDBAB_01238 1.9e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
NICGDBAB_01240 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
NICGDBAB_01241 1.7e-51 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NICGDBAB_01242 6e-154 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NICGDBAB_01243 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NICGDBAB_01244 4.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
NICGDBAB_01245 6.2e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NICGDBAB_01246 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NICGDBAB_01247 1.3e-108 3.1.3.18 S IA, variant 1
NICGDBAB_01248 2.2e-117 lrgB M effector of murein hydrolase
NICGDBAB_01249 7.7e-56 lrgA S Effector of murein hydrolase LrgA
NICGDBAB_01251 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
NICGDBAB_01252 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NICGDBAB_01253 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NICGDBAB_01254 3.9e-104 wecD M Acetyltransferase GNAT family
NICGDBAB_01255 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NICGDBAB_01256 4.1e-127 GK ROK family
NICGDBAB_01257 6.9e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
NICGDBAB_01258 1.7e-62 XK27_08050 O HflC and HflK could regulate a protease
NICGDBAB_01259 6.2e-13 XK27_08050 O HflC and HflK could regulate a protease
NICGDBAB_01260 3.9e-75 XK27_01300 S ASCH
NICGDBAB_01262 7.3e-51 S Toxin-antitoxin system, toxin component, RelE family
NICGDBAB_01263 2e-29 K Helix-turn-helix XRE-family like proteins
NICGDBAB_01264 7.5e-09 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NICGDBAB_01265 1.1e-12
NICGDBAB_01266 6.6e-168 V MatE
NICGDBAB_01268 3.9e-110 C Fe-S oxidoreductases
NICGDBAB_01269 1.2e-176 EGP Major Facilitator Superfamily
NICGDBAB_01270 5.5e-258 I radical SAM domain protein
NICGDBAB_01272 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NICGDBAB_01273 1.8e-87 L transposase activity
NICGDBAB_01275 1.9e-107
NICGDBAB_01276 7.4e-90
NICGDBAB_01277 4.5e-21 XK27_08050 O HflC and HflK could regulate a protease
NICGDBAB_01279 1.4e-203 potD P spermidine putrescine ABC transporter
NICGDBAB_01280 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
NICGDBAB_01281 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
NICGDBAB_01282 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NICGDBAB_01283 7.8e-171 murB 1.3.1.98 M cell wall formation
NICGDBAB_01284 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NICGDBAB_01285 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NICGDBAB_01286 3e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NICGDBAB_01287 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NICGDBAB_01288 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
NICGDBAB_01289 0.0 ydaO E amino acid
NICGDBAB_01290 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NICGDBAB_01291 4.1e-37 ylqC L Belongs to the UPF0109 family
NICGDBAB_01292 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NICGDBAB_01293 1.5e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NICGDBAB_01294 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
NICGDBAB_01295 2.1e-74 S QueT transporter
NICGDBAB_01296 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NICGDBAB_01297 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NICGDBAB_01298 1.3e-85 ccl S cog cog4708
NICGDBAB_01299 2.4e-159 rbn E Belongs to the UPF0761 family
NICGDBAB_01300 3.6e-165 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NICGDBAB_01301 1.2e-230 ytoI K transcriptional regulator containing CBS domains
NICGDBAB_01302 1.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NICGDBAB_01303 1.3e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NICGDBAB_01304 0.0 comEC S Competence protein ComEC
NICGDBAB_01305 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NICGDBAB_01306 1.7e-142 plsC 2.3.1.51 I Acyltransferase
NICGDBAB_01307 1.8e-140 nodB3 G deacetylase
NICGDBAB_01308 7.1e-141 yabB 2.1.1.223 L Methyltransferase
NICGDBAB_01309 1e-41 yazA L endonuclease containing a URI domain
NICGDBAB_01310 3.4e-222 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NICGDBAB_01311 3.3e-153 corA P CorA-like protein
NICGDBAB_01312 3.3e-62 yjqA S Bacterial PH domain
NICGDBAB_01313 2.3e-99 thiT S Thiamine transporter
NICGDBAB_01314 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NICGDBAB_01315 7.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
NICGDBAB_01316 5.7e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NICGDBAB_01320 1.1e-155 cjaA ET ABC transporter substrate-binding protein
NICGDBAB_01321 1.7e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
NICGDBAB_01322 3e-106 P ABC transporter (Permease
NICGDBAB_01323 3.9e-114 papP P ABC transporter (Permease
NICGDBAB_01324 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NICGDBAB_01325 2e-29 copZ 2.7.7.77 P Heavy metal-associated domain protein
NICGDBAB_01326 0.0 copA 3.6.3.54 P P-type ATPase
NICGDBAB_01327 2.7e-73 copY K Copper transport repressor, CopY TcrY family
NICGDBAB_01328 6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NICGDBAB_01329 3.8e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NICGDBAB_01330 1.1e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
NICGDBAB_01331 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NICGDBAB_01332 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NICGDBAB_01333 1e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
NICGDBAB_01334 2.9e-254 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NICGDBAB_01335 1.8e-41 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
NICGDBAB_01336 0.0 ctpE P E1-E2 ATPase
NICGDBAB_01337 1.6e-27
NICGDBAB_01338 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NICGDBAB_01339 5.1e-47 L transposase activity
NICGDBAB_01340 6e-121 K transcriptional regulator, MerR family
NICGDBAB_01341 1.3e-102 dnaQ 2.7.7.7 L DNA polymerase III
NICGDBAB_01342 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
NICGDBAB_01343 4.8e-63 XK27_02560 S cog cog2151
NICGDBAB_01344 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NICGDBAB_01345 6.2e-207 ytfP S Flavoprotein
NICGDBAB_01347 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NICGDBAB_01348 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
NICGDBAB_01349 4.3e-181 ecsB U ABC transporter
NICGDBAB_01350 1.1e-130 ecsA V abc transporter atp-binding protein
NICGDBAB_01351 2.5e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NICGDBAB_01352 1.9e-09
NICGDBAB_01354 6.9e-19
NICGDBAB_01355 6.7e-07
NICGDBAB_01356 1.6e-77 sigH K DNA-templated transcription, initiation
NICGDBAB_01357 1.6e-146 ykuT M mechanosensitive ion channel
NICGDBAB_01358 1.1e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NICGDBAB_01359 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NICGDBAB_01360 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NICGDBAB_01361 4.2e-83 XK27_03960 S Protein of unknown function (DUF3013)
NICGDBAB_01362 3.1e-80 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NICGDBAB_01363 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
NICGDBAB_01364 3.7e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NICGDBAB_01365 1.5e-35 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NICGDBAB_01366 8.6e-45 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NICGDBAB_01367 2.1e-21 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NICGDBAB_01368 1e-241 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NICGDBAB_01369 5.3e-83 nrdI F Belongs to the NrdI family
NICGDBAB_01370 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NICGDBAB_01371 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NICGDBAB_01372 2e-08 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NICGDBAB_01373 3e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NICGDBAB_01374 2.3e-18 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NICGDBAB_01375 7e-38 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NICGDBAB_01376 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NICGDBAB_01377 1.2e-111 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NICGDBAB_01378 4.4e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NICGDBAB_01379 7.9e-200 yhjX P Major Facilitator
NICGDBAB_01380 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NICGDBAB_01381 5e-94 V VanZ like family
NICGDBAB_01382 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NICGDBAB_01383 1.9e-200 ylbM S Belongs to the UPF0348 family
NICGDBAB_01384 2e-140 yqeM Q Methyltransferase domain protein
NICGDBAB_01385 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NICGDBAB_01386 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NICGDBAB_01387 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NICGDBAB_01388 3.5e-49 yhbY J RNA-binding protein
NICGDBAB_01389 3.2e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NICGDBAB_01390 1.8e-98 yqeG S hydrolase of the HAD superfamily
NICGDBAB_01391 5.7e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NICGDBAB_01392 1.3e-57
NICGDBAB_01393 5.1e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NICGDBAB_01394 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NICGDBAB_01395 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NICGDBAB_01396 5.6e-258 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NICGDBAB_01397 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NICGDBAB_01398 1e-61 hlpA M Belongs to the NlpA lipoprotein family
NICGDBAB_01399 5.5e-40 hlpA M Belongs to the NlpA lipoprotein family
NICGDBAB_01400 7.5e-100 pncA Q isochorismatase
NICGDBAB_01401 2.8e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NICGDBAB_01402 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NICGDBAB_01403 6.9e-75 XK27_03180 T universal stress protein
NICGDBAB_01405 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NICGDBAB_01406 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NICGDBAB_01407 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NICGDBAB_01408 0.0 yjcE P NhaP-type Na H and K H antiporters
NICGDBAB_01410 1e-96 ytqB 2.1.1.176 J (SAM)-dependent
NICGDBAB_01411 5.7e-180 yhcC S radical SAM protein
NICGDBAB_01412 7.8e-194 ylbL T Belongs to the peptidase S16 family
NICGDBAB_01413 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NICGDBAB_01414 4.3e-92 rsmD 2.1.1.171 L Methyltransferase
NICGDBAB_01415 5.5e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NICGDBAB_01416 1.1e-09 S Protein of unknown function (DUF4059)
NICGDBAB_01417 1.3e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
NICGDBAB_01418 2.3e-162 yxeN P ABC transporter (Permease
NICGDBAB_01419 4.8e-151 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NICGDBAB_01421 8.8e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NICGDBAB_01422 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NICGDBAB_01423 6.2e-64 cah 4.2.1.1 P carbonic anhydrase
NICGDBAB_01424 4.9e-38 cah 4.2.1.1 P carbonate dehydratase activity
NICGDBAB_01425 1e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NICGDBAB_01426 1.6e-09 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
NICGDBAB_01427 3.9e-42 D nuclear chromosome segregation
NICGDBAB_01428 1e-31 D nuclear chromosome segregation
NICGDBAB_01429 1.2e-32 L DNA integration
NICGDBAB_01430 4.8e-58 L Phage integrase family
NICGDBAB_01431 7.6e-118 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
NICGDBAB_01432 3.5e-124 ybbM S Uncharacterised protein family (UPF0014)
NICGDBAB_01433 5.2e-116 ybbL S abc transporter atp-binding protein
NICGDBAB_01434 3.1e-31
NICGDBAB_01435 3.8e-184 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NICGDBAB_01436 2.8e-137 cppA E CppA N-terminal
NICGDBAB_01437 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NICGDBAB_01438 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NICGDBAB_01441 3e-47 spiA K sequence-specific DNA binding
NICGDBAB_01442 1.8e-138 blpT
NICGDBAB_01443 1.1e-121 L Transposase
NICGDBAB_01444 2.1e-137 alkA 4.2.99.18 L 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NICGDBAB_01445 1.2e-19 C geranylgeranyl reductase activity
NICGDBAB_01446 1.8e-49 P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NICGDBAB_01447 1.5e-23 M Protein conserved in bacteria
NICGDBAB_01449 2.7e-196 L transposase, IS4 family
NICGDBAB_01450 1.7e-28 S TIR domain
NICGDBAB_01452 1.8e-31 K Helix-turn-helix domain
NICGDBAB_01453 1.3e-92
NICGDBAB_01454 8.5e-196 int L Belongs to the 'phage' integrase family
NICGDBAB_01455 2.8e-39 S Helix-turn-helix domain
NICGDBAB_01456 1.7e-117
NICGDBAB_01458 6.8e-76 isp2 S pathogenesis
NICGDBAB_01459 1.2e-120 tnp L Transposase IS66 family
NICGDBAB_01467 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
NICGDBAB_01470 1.6e-134 agrA KT phosphorelay signal transduction system
NICGDBAB_01471 4.6e-236 blpH 2.7.13.3 T protein histidine kinase activity
NICGDBAB_01473 2.8e-143 mesE M Transport protein ComB
NICGDBAB_01474 4.4e-75 mesE M Transport protein ComB
NICGDBAB_01475 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NICGDBAB_01476 0.0 mdlB V abc transporter atp-binding protein
NICGDBAB_01477 0.0 mdlA V abc transporter atp-binding protein
NICGDBAB_01479 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
NICGDBAB_01480 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NICGDBAB_01481 2.4e-66 yutD J protein conserved in bacteria
NICGDBAB_01482 1.9e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NICGDBAB_01484 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NICGDBAB_01485 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NICGDBAB_01486 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NICGDBAB_01487 4.3e-47 ftsL D cell division protein FtsL
NICGDBAB_01488 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NICGDBAB_01489 1.6e-65
NICGDBAB_01490 7.4e-27
NICGDBAB_01491 2.6e-30
NICGDBAB_01493 8.7e-33 yhaI J Protein of unknown function (DUF805)
NICGDBAB_01494 4.5e-18 D nuclear chromosome segregation
NICGDBAB_01495 3.8e-224 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NICGDBAB_01496 2.6e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NICGDBAB_01497 2.2e-285 XK27_00765
NICGDBAB_01498 8.1e-134 ecsA_2 V abc transporter atp-binding protein
NICGDBAB_01499 6.8e-125 S Protein of unknown function (DUF554)
NICGDBAB_01500 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NICGDBAB_01501 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NICGDBAB_01502 2.6e-121 liaI S membrane
NICGDBAB_01503 5.2e-75 XK27_02470 K LytTr DNA-binding domain
NICGDBAB_01504 2e-52 KT response to antibiotic
NICGDBAB_01505 1.4e-08 KT response to antibiotic
NICGDBAB_01506 9.1e-18 KT response to antibiotic
NICGDBAB_01507 9.8e-80 yebC M Membrane
NICGDBAB_01508 1.1e-16 yebC M Membrane
NICGDBAB_01509 2.6e-258 XK27_03190 S hydrolases of the HAD superfamily
NICGDBAB_01510 1.5e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NICGDBAB_01511 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NICGDBAB_01512 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NICGDBAB_01513 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NICGDBAB_01514 2.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NICGDBAB_01515 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NICGDBAB_01516 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NICGDBAB_01518 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NICGDBAB_01519 5.3e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NICGDBAB_01520 0.0 scrA 2.7.1.211 G pts system
NICGDBAB_01521 6.6e-289 scrB 3.2.1.26 GH32 G invertase
NICGDBAB_01522 3.2e-178 scrR K Transcriptional
NICGDBAB_01523 3.6e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NICGDBAB_01524 3.4e-62 yqhY S protein conserved in bacteria
NICGDBAB_01525 9.3e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NICGDBAB_01526 1.1e-83 comEB 3.5.4.12 F ComE operon protein 2
NICGDBAB_01527 7.2e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NICGDBAB_01530 2.6e-11 V 'abc transporter, ATP-binding protein
NICGDBAB_01531 2.9e-58 V 'abc transporter, ATP-binding protein
NICGDBAB_01537 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NICGDBAB_01538 5e-168 corA P COG0598 Mg2 and Co2 transporters
NICGDBAB_01539 2e-123 XK27_01040 S Pfam PF06570
NICGDBAB_01541 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NICGDBAB_01542 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NICGDBAB_01543 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NICGDBAB_01544 2.8e-41 XK27_05745
NICGDBAB_01546 3.6e-229 mutY L A G-specific adenine glycosylase
NICGDBAB_01550 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NICGDBAB_01551 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NICGDBAB_01552 6.7e-93 cvpA S toxin biosynthetic process
NICGDBAB_01553 4.7e-14 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NICGDBAB_01554 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NICGDBAB_01555 6.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NICGDBAB_01556 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NICGDBAB_01557 8.8e-48 azlD E branched-chain amino acid
NICGDBAB_01558 1.9e-116 azlC E AzlC protein
NICGDBAB_01559 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NICGDBAB_01560 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NICGDBAB_01561 2.1e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NICGDBAB_01562 2.5e-33 ykzG S Belongs to the UPF0356 family
NICGDBAB_01563 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NICGDBAB_01564 3.2e-41 pscB M CHAP domain protein
NICGDBAB_01566 9.9e-263 glnA 6.3.1.2 E glutamine synthetase
NICGDBAB_01567 8.5e-63 glnR K Transcriptional regulator
NICGDBAB_01568 1.3e-87 S Fusaric acid resistance protein-like
NICGDBAB_01569 1.5e-12
NICGDBAB_01570 1.7e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NICGDBAB_01571 7.9e-41 L COG1943 Transposase and inactivated derivatives
NICGDBAB_01572 9.7e-43 L transposase activity
NICGDBAB_01573 2.2e-18 L Transposase
NICGDBAB_01574 4.2e-28 L Integrase core domain protein
NICGDBAB_01575 2.7e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NICGDBAB_01576 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NICGDBAB_01577 7.4e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NICGDBAB_01578 5.1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NICGDBAB_01579 7e-142 purR 2.4.2.7 F operon repressor
NICGDBAB_01580 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
NICGDBAB_01581 4.5e-172 rmuC S RmuC domain protein
NICGDBAB_01582 9.2e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
NICGDBAB_01583 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NICGDBAB_01584 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NICGDBAB_01586 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NICGDBAB_01587 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NICGDBAB_01588 4.1e-144 tatD L Hydrolase, tatd
NICGDBAB_01589 1.9e-74 yccU S CoA-binding protein
NICGDBAB_01590 1.1e-50 trxA O Belongs to the thioredoxin family
NICGDBAB_01591 7.8e-143 S Macro domain protein
NICGDBAB_01592 2.8e-13 L thioesterase
NICGDBAB_01593 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
NICGDBAB_01594 6.4e-41 L Transposase
NICGDBAB_01595 3.8e-140 L Transposase
NICGDBAB_01598 6.3e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NICGDBAB_01599 1.1e-83 L Transposase
NICGDBAB_01600 1e-13 rpmH J Ribosomal protein L34
NICGDBAB_01601 8.4e-262 S PFAM Uncharacterised protein family UPF0236
NICGDBAB_01602 3.4e-73 D Filamentation induced by cAMP protein fic
NICGDBAB_01603 3.3e-52 L Integrase core domain
NICGDBAB_01604 0.0 3.6.3.4 P P-type ATPase
NICGDBAB_01605 1.4e-27 copZ 2.7.7.77 P Heavy-metal-associated domain
NICGDBAB_01606 1.2e-77 copA 3.6.3.54 P P-type ATPase
NICGDBAB_01607 3.4e-71 mntH P H( )-stimulated, divalent metal cation uptake system
NICGDBAB_01608 8.8e-72 T Belongs to the universal stress protein A family
NICGDBAB_01609 6.5e-162 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NICGDBAB_01610 3.8e-48 3.6.3.4 P P-type ATPase
NICGDBAB_01611 2.6e-42 arsB 1.20.4.1 P Sodium Bile acid symporter family
NICGDBAB_01613 1.9e-89 D CobQ CobB MinD ParA nucleotide binding domain protein
NICGDBAB_01614 8.6e-232 S Psort location CytoplasmicMembrane, score
NICGDBAB_01616 2.2e-81 tnpR L Resolvase, N terminal domain
NICGDBAB_01618 1.5e-281 U relaxase
NICGDBAB_01619 1.7e-23 S Bacterial mobilisation protein (MobC)
NICGDBAB_01621 0.0 2.1.1.72, 3.1.21.3 L Psort location Cytoplasmic, score
NICGDBAB_01623 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NICGDBAB_01626 0.0 U An automated process has identified a potential problem with this gene model
NICGDBAB_01627 8e-45 S Protein of unknown function (DUF3801)
NICGDBAB_01628 8.2e-55
NICGDBAB_01630 3e-63 ssb L single-stranded DNA binding
NICGDBAB_01631 7e-99
NICGDBAB_01632 0.0 M CHAP domain protein
NICGDBAB_01633 0.0 U Psort location Cytoplasmic, score
NICGDBAB_01634 1.6e-42 S PrgI family protein
NICGDBAB_01635 6.7e-91
NICGDBAB_01636 4.1e-24
NICGDBAB_01637 8.9e-15
NICGDBAB_01638 0.0 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NICGDBAB_01639 5.6e-19 MU outer membrane autotransporter barrel domain protein
NICGDBAB_01640 7e-13
NICGDBAB_01642 6.2e-87 repA S Replication initiator protein A
NICGDBAB_01645 3.2e-184 jag S RNA-binding protein
NICGDBAB_01646 8.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NICGDBAB_01647 1.3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NICGDBAB_01648 4.6e-263 argH 4.3.2.1 E Argininosuccinate lyase
NICGDBAB_01649 2.9e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NICGDBAB_01650 1.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NICGDBAB_01651 9.6e-90 amiA E ABC transporter, substrate-binding protein, family 5
NICGDBAB_01652 3e-182 amiA E ABC transporter, substrate-binding protein, family 5
NICGDBAB_01653 1.8e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NICGDBAB_01654 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NICGDBAB_01655 3.5e-50 S Protein of unknown function (DUF3397)
NICGDBAB_01656 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NICGDBAB_01657 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
NICGDBAB_01658 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
NICGDBAB_01659 1.4e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
NICGDBAB_01660 9.9e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NICGDBAB_01661 2.4e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
NICGDBAB_01662 7e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NICGDBAB_01663 1.8e-19 XK27_09620 S FMN reductase (NADPH) activity
NICGDBAB_01664 4.6e-35 XK27_09620 S FMN reductase (NADPH) activity
NICGDBAB_01665 7.4e-220 XK27_09615 C reductase
NICGDBAB_01666 2.1e-91 fnt P Formate nitrite transporter
NICGDBAB_01667 3.5e-32 XK27_08585 S Psort location CytoplasmicMembrane, score
NICGDBAB_01668 4.7e-29 XK27_08585 S Psort location CytoplasmicMembrane, score
NICGDBAB_01669 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NICGDBAB_01670 1.6e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NICGDBAB_01671 2.6e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NICGDBAB_01672 2.9e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NICGDBAB_01673 1e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NICGDBAB_01674 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NICGDBAB_01675 7.8e-48 S glycolate biosynthetic process
NICGDBAB_01676 4.9e-63 S phosphatase activity
NICGDBAB_01677 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
NICGDBAB_01680 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NICGDBAB_01681 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NICGDBAB_01682 4.1e-36 yeeD O sulfur carrier activity
NICGDBAB_01683 2.8e-188 yeeE S Sulphur transport
NICGDBAB_01684 3.9e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NICGDBAB_01685 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NICGDBAB_01686 1.8e-09 S Domain of unknown function (DUF4651)
NICGDBAB_01687 3.7e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NICGDBAB_01688 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NICGDBAB_01689 3.3e-110 S CAAX amino terminal protease family protein
NICGDBAB_01691 4.2e-66 V CAAX protease self-immunity
NICGDBAB_01692 1.3e-31 V CAAX protease self-immunity
NICGDBAB_01693 2.6e-26 lanR K sequence-specific DNA binding
NICGDBAB_01694 3.2e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NICGDBAB_01695 4.2e-175 ytxK 2.1.1.72 L DNA methylase
NICGDBAB_01696 2.2e-11 comGF U Putative Competence protein ComGF
NICGDBAB_01697 1.1e-69 comGF U Competence protein ComGF
NICGDBAB_01698 3.2e-15 NU Type II secretory pathway pseudopilin
NICGDBAB_01699 2.6e-56 cglD NU Competence protein
NICGDBAB_01700 8.5e-43 comGC U Required for transformation and DNA binding
NICGDBAB_01701 4.5e-152 cglB NU type II secretion system
NICGDBAB_01702 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NICGDBAB_01703 3.2e-67 S cog cog4699
NICGDBAB_01704 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NICGDBAB_01705 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NICGDBAB_01706 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NICGDBAB_01707 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NICGDBAB_01708 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NICGDBAB_01709 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
NICGDBAB_01710 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NICGDBAB_01711 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NICGDBAB_01712 1.1e-300 yloV S kinase related to dihydroxyacetone kinase
NICGDBAB_01713 5.2e-57 asp S cog cog1302
NICGDBAB_01714 2.7e-225 norN V Mate efflux family protein
NICGDBAB_01715 1.9e-278 thrC 4.2.3.1 E Threonine synthase
NICGDBAB_01716 2.6e-39 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NICGDBAB_01717 2.3e-66 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NICGDBAB_01718 2.3e-137 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NICGDBAB_01719 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
NICGDBAB_01720 0.0 pepO 3.4.24.71 O Peptidase family M13
NICGDBAB_01721 5.4e-114 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NICGDBAB_01722 1.7e-34 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NICGDBAB_01723 6.5e-12 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NICGDBAB_01724 2.4e-54 treB 2.7.1.201 G PTS System
NICGDBAB_01725 4.7e-85 treR K trehalose operon
NICGDBAB_01726 3.3e-95 ywlG S Belongs to the UPF0340 family
NICGDBAB_01729 2.7e-13 L PFAM Integrase, catalytic core
NICGDBAB_01730 4.3e-77 L PFAM Integrase, catalytic core
NICGDBAB_01731 4.4e-56 L Transposase IS116 IS110 IS902
NICGDBAB_01732 7.8e-135 L COG3547 Transposase and inactivated derivatives
NICGDBAB_01733 1.1e-43 J glyoxalase III activity
NICGDBAB_01734 1.9e-10 V Transport permease protein
NICGDBAB_01735 6.2e-30 T Histidine kinase
NICGDBAB_01736 2.2e-111
NICGDBAB_01737 1.9e-47
NICGDBAB_01738 2e-105
NICGDBAB_01740 5.2e-102 yiiE S protein homotetramerization
NICGDBAB_01741 1.8e-157 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NICGDBAB_01742 8.9e-105 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NICGDBAB_01743 3.9e-31
NICGDBAB_01744 1.2e-40
NICGDBAB_01745 1.7e-220 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NICGDBAB_01746 1.3e-109 K Peptidase S24-like
NICGDBAB_01747 6.6e-127 E IrrE N-terminal-like domain
NICGDBAB_01749 1.5e-45 K Transcriptional
NICGDBAB_01750 1.3e-42
NICGDBAB_01751 1.2e-71
NICGDBAB_01752 7e-274 ydcQ D Ftsk spoiiie family protein
NICGDBAB_01753 1.2e-222 K Replication initiation factor
NICGDBAB_01754 4.3e-33
NICGDBAB_01755 6.7e-88
NICGDBAB_01756 2.9e-158 S Conjugative transposon protein TcpC
NICGDBAB_01757 3.2e-33
NICGDBAB_01758 5.1e-69 S TcpE family
NICGDBAB_01759 0.0 yddE S AAA-like domain
NICGDBAB_01760 5.1e-265
NICGDBAB_01761 2.8e-29
NICGDBAB_01762 7.1e-166 isp2 S pathogenesis
NICGDBAB_01763 4e-16
NICGDBAB_01764 2.2e-185 L Phage integrase family
NICGDBAB_01765 2.8e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
NICGDBAB_01767 2.1e-64 6.3.2.2 H ergothioneine biosynthetic process
NICGDBAB_01768 3.4e-116 6.3.2.2 H gamma-glutamylcysteine synthetase
NICGDBAB_01769 9.4e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
NICGDBAB_01770 2.7e-13 L PFAM Integrase, catalytic core
NICGDBAB_01771 2.5e-72 L PFAM Integrase, catalytic core
NICGDBAB_01772 3.3e-62 rplQ J ribosomal protein l17
NICGDBAB_01773 8.1e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NICGDBAB_01774 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NICGDBAB_01775 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NICGDBAB_01776 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NICGDBAB_01777 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NICGDBAB_01778 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NICGDBAB_01779 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NICGDBAB_01780 1.3e-57 rplO J binds to the 23S rRNA
NICGDBAB_01781 2.5e-23 rpmD J ribosomal protein l30
NICGDBAB_01782 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NICGDBAB_01783 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NICGDBAB_01784 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NICGDBAB_01785 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NICGDBAB_01786 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NICGDBAB_01787 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NICGDBAB_01788 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NICGDBAB_01789 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NICGDBAB_01790 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NICGDBAB_01791 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NICGDBAB_01792 1e-69 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NICGDBAB_01793 7.5e-115 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NICGDBAB_01794 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NICGDBAB_01795 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NICGDBAB_01796 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NICGDBAB_01797 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NICGDBAB_01798 2.2e-103 rplD J Forms part of the polypeptide exit tunnel
NICGDBAB_01799 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NICGDBAB_01800 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NICGDBAB_01801 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NICGDBAB_01802 0.0 XK27_09800 I Acyltransferase
NICGDBAB_01803 1.7e-35 XK27_09805 S MORN repeat protein
NICGDBAB_01804 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NICGDBAB_01805 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NICGDBAB_01806 8.8e-83 adk 2.7.4.3 F topology modulation protein
NICGDBAB_01807 1.9e-161 yxaM EGP Major facilitator Superfamily
NICGDBAB_01808 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
NICGDBAB_01810 3.8e-154 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NICGDBAB_01811 2.8e-252 KLT serine threonine protein kinase
NICGDBAB_01814 1e-123 glnQ E abc transporter atp-binding protein
NICGDBAB_01815 2.4e-276 glnP P ABC transporter
NICGDBAB_01816 2e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NICGDBAB_01817 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NICGDBAB_01818 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
NICGDBAB_01819 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NICGDBAB_01820 4.1e-234 sufD O assembly protein SufD
NICGDBAB_01821 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NICGDBAB_01822 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
NICGDBAB_01823 1.2e-271 sufB O assembly protein SufB
NICGDBAB_01824 8.3e-304 oppA E ABC transporter substrate-binding protein
NICGDBAB_01825 2.4e-159 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NICGDBAB_01826 1.2e-162 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NICGDBAB_01827 3.6e-188 oppD P Belongs to the ABC transporter superfamily
NICGDBAB_01828 8.1e-163 oppF P Belongs to the ABC transporter superfamily
NICGDBAB_01830 5.6e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NICGDBAB_01831 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NICGDBAB_01832 6e-128 K sequence-specific DNA binding
NICGDBAB_01833 0.0 KLT serine threonine protein kinase
NICGDBAB_01834 1.9e-223 EGP Major facilitator Superfamily
NICGDBAB_01835 3.1e-72 adcR K transcriptional
NICGDBAB_01836 2.2e-136 adcC P ABC transporter, ATP-binding protein
NICGDBAB_01837 1.9e-128 adcB P ABC transporter (Permease
NICGDBAB_01838 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NICGDBAB_01839 1.3e-64 ptsG 2.7.1.199, 2.7.1.208 G pts system
NICGDBAB_01840 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
NICGDBAB_01841 4.2e-257 ptsG 2.7.1.199, 2.7.1.208 G pts system
NICGDBAB_01842 9.8e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
NICGDBAB_01843 3.4e-255 pgi 5.3.1.9 G Belongs to the GPI family
NICGDBAB_01844 1.2e-126 yeeN K transcriptional regulatory protein
NICGDBAB_01845 9.8e-50 yajC U protein transport
NICGDBAB_01846 2.4e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NICGDBAB_01847 5e-145 cdsA 2.7.7.41 S Belongs to the CDS family
NICGDBAB_01848 1e-229 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NICGDBAB_01849 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NICGDBAB_01850 0.0 WQ51_06230 S ABC transporter substrate binding protein
NICGDBAB_01851 5.2e-142 cmpC S abc transporter atp-binding protein
NICGDBAB_01852 2e-126 KLT serine threonine protein kinase
NICGDBAB_01853 2.1e-280 V ABC transporter
NICGDBAB_01854 3.3e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NICGDBAB_01855 7e-127 Z012_04635 K sequence-specific DNA binding
NICGDBAB_01857 1.6e-53 C Radical SAM
NICGDBAB_01858 1.3e-159 C Radical SAM
NICGDBAB_01859 5.6e-286 V ABC transporter transmembrane region
NICGDBAB_01860 2.5e-89 K sequence-specific DNA binding
NICGDBAB_01861 2.2e-155 L Replication initiation factor
NICGDBAB_01862 1.9e-18 S Domain of unknown function (DUF3173)
NICGDBAB_01863 2.2e-215 int L Belongs to the 'phage' integrase family
NICGDBAB_01865 1.1e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NICGDBAB_01866 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NICGDBAB_01867 2.2e-44 yrzL S Belongs to the UPF0297 family
NICGDBAB_01868 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NICGDBAB_01869 4.2e-44 yrzB S Belongs to the UPF0473 family
NICGDBAB_01870 4.4e-297 ccs S the current gene model (or a revised gene model) may contain a frame shift
NICGDBAB_01871 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NICGDBAB_01872 7.5e-14
NICGDBAB_01873 1.1e-89 XK27_10930 K acetyltransferase
NICGDBAB_01874 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NICGDBAB_01875 1.4e-142 yaaA S Belongs to the UPF0246 family
NICGDBAB_01876 9.9e-169 XK27_01785 S cog cog1284
NICGDBAB_01877 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NICGDBAB_01879 1e-240 hisS 6.1.1.21 J histidyl-tRNA synthetase
NICGDBAB_01880 4e-53 metE 2.1.1.14 E Methionine synthase
NICGDBAB_01881 2.6e-64 metE 2.1.1.14 E Methionine synthase
NICGDBAB_01882 1.4e-36 metE 2.1.1.14 E Methionine synthase
NICGDBAB_01883 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NICGDBAB_01884 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NICGDBAB_01887 1.3e-138 yegS 2.7.1.107 I Diacylglycerol kinase
NICGDBAB_01888 3.6e-95 S Hydrophobic domain protein
NICGDBAB_01889 5.8e-19 K Replication initiation factor
NICGDBAB_01890 4.8e-48 S Protein of unknown function with HXXEE motif
NICGDBAB_01892 3.7e-27 S Membrane
NICGDBAB_01893 1.7e-99
NICGDBAB_01894 1.8e-23 S Small integral membrane protein
NICGDBAB_01895 6.5e-83 M Protein conserved in bacteria
NICGDBAB_01896 1.1e-11 K CsbD-like
NICGDBAB_01897 3.6e-34 L Transposase
NICGDBAB_01898 7.3e-48 K Peptidase S24-like protein
NICGDBAB_01899 7.1e-09 K Peptidase S24-like protein
NICGDBAB_01900 3e-55 E IrrE N-terminal-like domain
NICGDBAB_01901 1.6e-49 E IrrE N-terminal-like domain
NICGDBAB_01902 4.3e-61 L COG2801 Transposase and inactivated derivatives
NICGDBAB_01903 8.3e-106 S Putative adhesin
NICGDBAB_01904 4e-158 XK27_06930 V domain protein
NICGDBAB_01905 5.4e-95 XK27_06935 K transcriptional regulator
NICGDBAB_01906 2.9e-52 ypaA S membrane
NICGDBAB_01907 2e-07
NICGDBAB_01908 4.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NICGDBAB_01909 8.2e-48 veg S Biofilm formation stimulator VEG
NICGDBAB_01910 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NICGDBAB_01911 8.5e-73 rplI J binds to the 23S rRNA
NICGDBAB_01912 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NICGDBAB_01913 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NICGDBAB_01914 2e-74 F NUDIX domain
NICGDBAB_01915 2.4e-214 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NICGDBAB_01916 6.8e-301 S Bacterial membrane protein, YfhO
NICGDBAB_01917 1.5e-32 isaA GH23 M Immunodominant staphylococcal antigen A
NICGDBAB_01918 3.9e-80 lytE M LysM domain protein
NICGDBAB_01919 1e-134 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NICGDBAB_01920 2.6e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NICGDBAB_01921 6.3e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NICGDBAB_01922 2.6e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NICGDBAB_01923 7e-137 ymfM S sequence-specific DNA binding
NICGDBAB_01924 3.3e-239 ymfH S Peptidase M16
NICGDBAB_01925 4.5e-233 ymfF S Peptidase M16
NICGDBAB_01926 3.6e-45 yaaA S S4 domain protein YaaA
NICGDBAB_01927 2.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NICGDBAB_01928 4.7e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NICGDBAB_01929 1.4e-192 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NICGDBAB_01930 5.4e-153 yvjA S membrane
NICGDBAB_01931 6.7e-306 ybiT S abc transporter atp-binding protein
NICGDBAB_01932 0.0 XK27_10405 S Bacterial membrane protein YfhO
NICGDBAB_01936 1.4e-119 yoaK S Psort location CytoplasmicMembrane, score
NICGDBAB_01937 7.3e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NICGDBAB_01938 1.5e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NICGDBAB_01939 1e-134 parB K Belongs to the ParB family
NICGDBAB_01940 4.8e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NICGDBAB_01941 2.4e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NICGDBAB_01942 4.1e-29 yyzM S Protein conserved in bacteria
NICGDBAB_01943 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NICGDBAB_01944 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NICGDBAB_01945 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NICGDBAB_01946 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NICGDBAB_01947 2.7e-61 divIC D Septum formation initiator
NICGDBAB_01949 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NICGDBAB_01950 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NICGDBAB_01951 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NICGDBAB_01952 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NICGDBAB_01953 1.7e-162 L Transposase
NICGDBAB_01954 2.8e-222 ydcQ D Ftsk spoiiie family protein
NICGDBAB_01955 8.5e-49
NICGDBAB_01956 2.3e-34
NICGDBAB_01958 9e-35 K sequence-specific DNA binding
NICGDBAB_01959 6.8e-63 L PFAM Integrase catalytic region
NICGDBAB_01960 1.6e-56 L PFAM Integrase catalytic region
NICGDBAB_01961 1.5e-28 S Transglycosylase associated protein
NICGDBAB_01962 4.2e-37
NICGDBAB_01963 1.5e-10 S Small integral membrane protein
NICGDBAB_01964 1.9e-65 S Asp23 family, cell envelope-related function
NICGDBAB_01965 2.2e-14 S Belongs to the UPF0337 (CsbD) family
NICGDBAB_01966 1.3e-59 S Asp23 family, cell envelope-related function
NICGDBAB_01968 6.8e-63 L PFAM Integrase catalytic region
NICGDBAB_01969 1.2e-56 L PFAM Integrase catalytic region
NICGDBAB_01970 1.5e-17
NICGDBAB_01971 2.6e-106 tnp4 L L COG3328 Transposase and inactivated derivatives
NICGDBAB_01972 7.2e-45 infB M domain protein
NICGDBAB_01974 8.4e-114 K Psort location Cytoplasmic, score
NICGDBAB_01975 1.6e-11 K Transcriptional
NICGDBAB_01977 3.5e-87 L Replication initiation factor
NICGDBAB_01978 4.5e-10 S Domain of unknown function (DUF3173)
NICGDBAB_01979 8.2e-218 L Belongs to the 'phage' integrase family
NICGDBAB_01980 6.3e-12 S Conjugative transposon protein TcpC
NICGDBAB_01981 0.0 tetP J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NICGDBAB_01982 2.3e-17 L COG2801 Transposase and inactivated derivatives
NICGDBAB_01983 3.5e-112 K sequence-specific DNA binding
NICGDBAB_01984 2.2e-10 C Arylsulfatase regulator (Fe-S oxidoreductase)
NICGDBAB_01985 1e-69 doc S Prophage maintenance system killer protein
NICGDBAB_01986 3.3e-30 S Antidote-toxin recognition MazE, bacterial antitoxin
NICGDBAB_01987 8.5e-09
NICGDBAB_01988 5.1e-40 L transposition
NICGDBAB_01989 2.6e-18
NICGDBAB_01990 7.6e-118 L Transposase
NICGDBAB_01991 3.2e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NICGDBAB_01992 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NICGDBAB_01993 1.6e-83 L Transposase
NICGDBAB_01994 7.2e-104 L Transposase
NICGDBAB_01995 5.9e-28 K Transcriptional regulator
NICGDBAB_01996 1.7e-36 3.5.2.6 V Beta-lactamase
NICGDBAB_01997 9.4e-61 S very-long-chain-acyl-CoA dehydrogenase activity
NICGDBAB_01998 3.9e-71
NICGDBAB_02000 1.6e-70 nosF V abc transporter atp-binding protein
NICGDBAB_02001 4.9e-17
NICGDBAB_02002 2.4e-135 V ABC transporter
NICGDBAB_02003 1.9e-107 CP ABC-2 family transporter protein
NICGDBAB_02004 5e-135 1.6.5.5 C NADPH:quinone reductase activity
NICGDBAB_02005 1.4e-19 L Transposase
NICGDBAB_02006 1.7e-85 L the current gene model (or a revised gene model) may contain a frame shift
NICGDBAB_02009 5.3e-16
NICGDBAB_02010 1.7e-54 S TM2 domain
NICGDBAB_02011 3.4e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NICGDBAB_02012 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NICGDBAB_02013 2.2e-24 secE U Belongs to the SecE SEC61-gamma family
NICGDBAB_02014 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
NICGDBAB_02015 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NICGDBAB_02016 4e-47 cof Q phosphatase activity
NICGDBAB_02017 1.1e-34 cof Q phosphatase activity
NICGDBAB_02018 8.7e-99 glcR K transcriptional regulator (DeoR family)
NICGDBAB_02019 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NICGDBAB_02020 3.8e-40 K transcriptional
NICGDBAB_02021 7.4e-89 S thiolester hydrolase activity
NICGDBAB_02022 8.7e-139 S COG1073 Hydrolases of the alpha beta superfamily
NICGDBAB_02023 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NICGDBAB_02024 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NICGDBAB_02025 3.2e-77 yhaI L Membrane
NICGDBAB_02026 1.5e-258 pepC 3.4.22.40 E aminopeptidase
NICGDBAB_02027 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NICGDBAB_02028 6.9e-107 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NICGDBAB_02029 1.3e-93 ypsA S Belongs to the UPF0398 family
NICGDBAB_02030 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NICGDBAB_02031 3.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NICGDBAB_02032 6.5e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NICGDBAB_02033 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NICGDBAB_02034 2.5e-23
NICGDBAB_02035 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NICGDBAB_02036 7.3e-80 XK27_09675 K -acetyltransferase
NICGDBAB_02037 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NICGDBAB_02038 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NICGDBAB_02039 7.1e-46 L Integrase core domain protein
NICGDBAB_02040 1.6e-32 L Integrase core domain protein
NICGDBAB_02041 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NICGDBAB_02042 6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NICGDBAB_02043 1.9e-130 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NICGDBAB_02044 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NICGDBAB_02045 1.5e-97 ybhL S Belongs to the BI1 family
NICGDBAB_02048 2.8e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NICGDBAB_02049 5.8e-89 K transcriptional regulator
NICGDBAB_02050 7.6e-36 yneF S UPF0154 protein
NICGDBAB_02051 7.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NICGDBAB_02052 2.7e-185 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NICGDBAB_02053 3.5e-99 XK27_09740 S Phosphoesterase
NICGDBAB_02054 2.1e-85 ykuL S CBS domain
NICGDBAB_02055 2.8e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NICGDBAB_02056 1.5e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NICGDBAB_02057 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NICGDBAB_02058 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NICGDBAB_02059 4e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NICGDBAB_02060 4.8e-255 trkH P Cation transport protein
NICGDBAB_02061 1.4e-245 trkA P Potassium transporter peripheral membrane component
NICGDBAB_02062 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NICGDBAB_02063 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NICGDBAB_02064 6.5e-111 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NICGDBAB_02065 5.6e-161 K sequence-specific DNA binding
NICGDBAB_02066 2.1e-32 V protein secretion by the type I secretion system
NICGDBAB_02067 5.5e-105 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NICGDBAB_02068 4.4e-56 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NICGDBAB_02070 7e-23 S Cag pathogenicity island, type IV secretory system
NICGDBAB_02071 1e-45 M Glycosyltransferase family 92
NICGDBAB_02072 1.6e-84 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NICGDBAB_02073 2.8e-28 yhaI L Membrane
NICGDBAB_02074 1e-55 S Domain of unknown function (DUF4173)
NICGDBAB_02075 1.2e-94 ureI S AmiS/UreI family transporter
NICGDBAB_02076 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NICGDBAB_02077 3e-53 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NICGDBAB_02078 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NICGDBAB_02079 6.6e-78 ureE O enzyme active site formation
NICGDBAB_02080 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NICGDBAB_02081 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NICGDBAB_02082 3.7e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NICGDBAB_02083 3.9e-176 cbiM P PDGLE domain
NICGDBAB_02084 4.9e-137 P cobalt transport protein
NICGDBAB_02085 1.5e-129 cbiO P ABC transporter
NICGDBAB_02086 3e-148 ET amino acid transport
NICGDBAB_02087 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NICGDBAB_02088 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
NICGDBAB_02089 1.5e-173 EGP Transmembrane secretion effector
NICGDBAB_02090 4.5e-144 ET amino acid transport
NICGDBAB_02091 5.8e-158 metQ M Belongs to the NlpA lipoprotein family
NICGDBAB_02092 1.8e-256 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NICGDBAB_02093 2e-181 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NICGDBAB_02094 2e-97 metI P ABC transporter (Permease
NICGDBAB_02095 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NICGDBAB_02096 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NICGDBAB_02097 8e-94 S UPF0397 protein
NICGDBAB_02098 0.0 ykoD P abc transporter atp-binding protein
NICGDBAB_02099 1.2e-149 cbiQ P cobalt transport
NICGDBAB_02100 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NICGDBAB_02101 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
NICGDBAB_02102 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NICGDBAB_02103 3.4e-242 P COG0168 Trk-type K transport systems, membrane components
NICGDBAB_02104 9e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NICGDBAB_02105 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
NICGDBAB_02106 3.9e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NICGDBAB_02107 3e-276 T PhoQ Sensor
NICGDBAB_02108 1e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NICGDBAB_02109 1.9e-217 dnaB L Replication initiation and membrane attachment
NICGDBAB_02110 8.9e-167 dnaI L Primosomal protein DnaI
NICGDBAB_02111 3.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NICGDBAB_02112 8.3e-89 yrdC 3.5.1.19 Q isochorismatase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)