ORF_ID e_value Gene_name EC_number CAZy COGs Description
IHLHNAPA_00009 5.3e-11
IHLHNAPA_00015 1.3e-140 mreC M Involved in formation and maintenance of cell shape
IHLHNAPA_00016 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IHLHNAPA_00017 2e-96 usp 3.5.1.28 CBM50 S CHAP domain
IHLHNAPA_00018 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHLHNAPA_00019 2.5e-26
IHLHNAPA_00020 4.5e-219 araT 2.6.1.1 E Aminotransferase
IHLHNAPA_00021 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
IHLHNAPA_00022 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IHLHNAPA_00023 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHLHNAPA_00024 1.2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IHLHNAPA_00025 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHLHNAPA_00026 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHLHNAPA_00027 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IHLHNAPA_00028 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHLHNAPA_00029 7.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IHLHNAPA_00030 1e-90 L transposase activity
IHLHNAPA_00031 3.5e-50 L transposition
IHLHNAPA_00032 2e-32 L Integrase core domain protein
IHLHNAPA_00033 2.3e-161 S CHAP domain
IHLHNAPA_00034 2e-241 purD 6.3.4.13 F Belongs to the GARS family
IHLHNAPA_00035 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHLHNAPA_00036 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHLHNAPA_00037 9.2e-141 1.1.1.169 H Ketopantoate reductase
IHLHNAPA_00038 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHLHNAPA_00039 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IHLHNAPA_00040 8.2e-70 argR K Regulates arginine biosynthesis genes
IHLHNAPA_00041 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IHLHNAPA_00042 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHLHNAPA_00043 1.9e-80 S Protein of unknown function (DUF3021)
IHLHNAPA_00044 6.5e-63 KT phosphorelay signal transduction system
IHLHNAPA_00046 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IHLHNAPA_00048 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IHLHNAPA_00049 2.4e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
IHLHNAPA_00050 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
IHLHNAPA_00051 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHLHNAPA_00052 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
IHLHNAPA_00055 1.9e-07
IHLHNAPA_00060 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHLHNAPA_00061 2.3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IHLHNAPA_00062 5.5e-36 XK27_02060 S Transglycosylase associated protein
IHLHNAPA_00063 2.6e-55 badR K DNA-binding transcription factor activity
IHLHNAPA_00064 1e-96 S reductase
IHLHNAPA_00065 2.3e-31 L Integrase core domain protein
IHLHNAPA_00066 2.1e-34 L Integrase core domain protein
IHLHNAPA_00067 6.4e-41 L transposition
IHLHNAPA_00068 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
IHLHNAPA_00069 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IHLHNAPA_00072 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
IHLHNAPA_00073 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHLHNAPA_00074 5.5e-83 S Putative small multi-drug export protein
IHLHNAPA_00075 2.6e-74 ctsR K Belongs to the CtsR family
IHLHNAPA_00076 0.0 clpC O Belongs to the ClpA ClpB family
IHLHNAPA_00077 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IHLHNAPA_00078 1.7e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IHLHNAPA_00079 1.7e-38 L Transposase
IHLHNAPA_00080 5.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IHLHNAPA_00081 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IHLHNAPA_00082 5.9e-143 S SseB protein N-terminal domain
IHLHNAPA_00083 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
IHLHNAPA_00084 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHLHNAPA_00085 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IHLHNAPA_00088 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHLHNAPA_00089 7e-92 yacP S RNA-binding protein containing a PIN domain
IHLHNAPA_00090 4.4e-155 degV S DegV family
IHLHNAPA_00091 1.1e-20 K helix-turn-helix
IHLHNAPA_00092 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IHLHNAPA_00093 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHLHNAPA_00094 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IHLHNAPA_00095 4.1e-36 K sequence-specific DNA binding
IHLHNAPA_00097 0.0
IHLHNAPA_00098 1.8e-12 L Transposase
IHLHNAPA_00099 5.7e-91 tnp L Transposase
IHLHNAPA_00100 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
IHLHNAPA_00101 4.3e-109 capA M Bacterial capsule synthesis protein
IHLHNAPA_00102 1.5e-55 capA M Bacterial capsule synthesis protein
IHLHNAPA_00103 3.6e-39 gcvR T UPF0237 protein
IHLHNAPA_00104 1.7e-243 XK27_08635 S UPF0210 protein
IHLHNAPA_00105 2.4e-135 ais G Phosphoglycerate mutase
IHLHNAPA_00106 7.9e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IHLHNAPA_00107 1.5e-101 acmA 3.2.1.17 NU amidase activity
IHLHNAPA_00109 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IHLHNAPA_00110 5.3e-70 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHLHNAPA_00111 2.3e-294 dnaK O Heat shock 70 kDa protein
IHLHNAPA_00112 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IHLHNAPA_00113 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IHLHNAPA_00114 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
IHLHNAPA_00115 3.8e-31 hmpT S membrane
IHLHNAPA_00116 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
IHLHNAPA_00117 2.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IHLHNAPA_00118 6.5e-87
IHLHNAPA_00119 1.6e-77 sigH K DNA-templated transcription, initiation
IHLHNAPA_00120 3e-148 ykuT M mechanosensitive ion channel
IHLHNAPA_00121 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IHLHNAPA_00122 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IHLHNAPA_00123 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IHLHNAPA_00124 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
IHLHNAPA_00125 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
IHLHNAPA_00126 2e-177 prmA J Ribosomal protein L11 methyltransferase
IHLHNAPA_00127 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IHLHNAPA_00128 1.2e-13 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IHLHNAPA_00129 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IHLHNAPA_00130 1.8e-83 nrdI F Belongs to the NrdI family
IHLHNAPA_00131 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHLHNAPA_00132 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IHLHNAPA_00133 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IHLHNAPA_00134 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IHLHNAPA_00135 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IHLHNAPA_00136 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
IHLHNAPA_00137 3.9e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IHLHNAPA_00138 1.1e-110 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHLHNAPA_00139 2.9e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IHLHNAPA_00140 6.5e-202 yhjX P Major Facilitator
IHLHNAPA_00141 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHLHNAPA_00142 5e-94 V VanZ like family
IHLHNAPA_00144 1e-123 glnQ E abc transporter atp-binding protein
IHLHNAPA_00145 1.8e-276 glnP P ABC transporter
IHLHNAPA_00146 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IHLHNAPA_00147 1.5e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IHLHNAPA_00148 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
IHLHNAPA_00149 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IHLHNAPA_00150 6.3e-235 sufD O assembly protein SufD
IHLHNAPA_00151 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHLHNAPA_00152 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
IHLHNAPA_00153 3.5e-274 sufB O assembly protein SufB
IHLHNAPA_00154 1.9e-178 oppA E ABC transporter substrate-binding protein
IHLHNAPA_00155 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHLHNAPA_00156 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHLHNAPA_00157 5.3e-72 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHLHNAPA_00158 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHLHNAPA_00159 8e-28 oppD P Belongs to the ABC transporter superfamily
IHLHNAPA_00160 2.5e-32 oppD P Belongs to the ABC transporter superfamily
IHLHNAPA_00161 4.8e-67 oppD P Belongs to the ABC transporter superfamily
IHLHNAPA_00162 1.7e-30 oppD P Belongs to the ABC transporter superfamily
IHLHNAPA_00163 9e-170 oppF P Belongs to the ABC transporter superfamily
IHLHNAPA_00166 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IHLHNAPA_00167 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHLHNAPA_00168 1.9e-223 EGP Major facilitator Superfamily
IHLHNAPA_00169 3.1e-72 adcR K transcriptional
IHLHNAPA_00170 2.2e-136 adcC P ABC transporter, ATP-binding protein
IHLHNAPA_00171 4.6e-130 adcB P ABC transporter (Permease
IHLHNAPA_00172 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IHLHNAPA_00173 6.9e-28 ptsG 2.7.1.199, 2.7.1.208 G pts system
IHLHNAPA_00174 5.1e-149 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
IHLHNAPA_00175 8.3e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IHLHNAPA_00176 1.1e-149 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
IHLHNAPA_00177 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
IHLHNAPA_00178 1.9e-127 yeeN K transcriptional regulatory protein
IHLHNAPA_00179 9.8e-50 yajC U protein transport
IHLHNAPA_00180 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHLHNAPA_00181 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
IHLHNAPA_00182 5.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IHLHNAPA_00183 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IHLHNAPA_00184 0.0 WQ51_06230 S ABC transporter substrate binding protein
IHLHNAPA_00185 5.2e-142 cmpC S abc transporter atp-binding protein
IHLHNAPA_00186 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IHLHNAPA_00187 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IHLHNAPA_00188 4.4e-37 L Transposase
IHLHNAPA_00189 6.4e-18 L transposase activity
IHLHNAPA_00190 1.5e-30 L transposition
IHLHNAPA_00193 4.7e-43
IHLHNAPA_00194 3.4e-55 S TM2 domain
IHLHNAPA_00195 1.8e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHLHNAPA_00196 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHLHNAPA_00197 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
IHLHNAPA_00198 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
IHLHNAPA_00199 7.8e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
IHLHNAPA_00200 6e-55 cof Q phosphatase activity
IHLHNAPA_00201 1.1e-34 cof Q phosphatase activity
IHLHNAPA_00202 3.1e-136 glcR K transcriptional regulator (DeoR family)
IHLHNAPA_00203 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHLHNAPA_00205 3.8e-40 K transcriptional
IHLHNAPA_00207 2.6e-76 S thiolester hydrolase activity
IHLHNAPA_00208 1.3e-137 S COG1073 Hydrolases of the alpha beta superfamily
IHLHNAPA_00209 8.2e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHLHNAPA_00210 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IHLHNAPA_00211 1e-75 yhaI L Membrane
IHLHNAPA_00212 5.1e-259 pepC 3.4.22.40 E aminopeptidase
IHLHNAPA_00213 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHLHNAPA_00214 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IHLHNAPA_00215 1.3e-93 ypsA S Belongs to the UPF0398 family
IHLHNAPA_00216 7.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IHLHNAPA_00217 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IHLHNAPA_00218 1.9e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
IHLHNAPA_00219 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
IHLHNAPA_00220 2.5e-23
IHLHNAPA_00221 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IHLHNAPA_00222 3.1e-20 XK27_09675 K -acetyltransferase
IHLHNAPA_00223 9.3e-46 XK27_09675 K -acetyltransferase
IHLHNAPA_00224 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHLHNAPA_00225 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHLHNAPA_00227 3.7e-82 L Integrase core domain protein
IHLHNAPA_00228 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHLHNAPA_00229 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IHLHNAPA_00230 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHLHNAPA_00231 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
IHLHNAPA_00232 1.5e-97 ybhL S Belongs to the BI1 family
IHLHNAPA_00235 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IHLHNAPA_00236 8.1e-91 K transcriptional regulator
IHLHNAPA_00237 7.6e-36 yneF S UPF0154 protein
IHLHNAPA_00238 4.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IHLHNAPA_00239 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHLHNAPA_00240 3.5e-99 XK27_09740 S Phosphoesterase
IHLHNAPA_00241 7.8e-85 ykuL S CBS domain
IHLHNAPA_00242 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
IHLHNAPA_00243 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IHLHNAPA_00244 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IHLHNAPA_00245 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHLHNAPA_00246 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IHLHNAPA_00247 1.2e-258 trkH P Cation transport protein
IHLHNAPA_00248 1.8e-248 trkA P Potassium transporter peripheral membrane component
IHLHNAPA_00249 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IHLHNAPA_00250 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IHLHNAPA_00251 9.1e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
IHLHNAPA_00252 5.6e-161 K sequence-specific DNA binding
IHLHNAPA_00253 1.2e-32 V protein secretion by the type I secretion system
IHLHNAPA_00254 1.4e-108 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IHLHNAPA_00255 1.1e-34 V protein secretion by the type I secretion system
IHLHNAPA_00256 1.8e-27 comA V protein secretion by the type I secretion system
IHLHNAPA_00257 5.4e-66 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IHLHNAPA_00258 6e-46 yhaI L Membrane
IHLHNAPA_00259 9.2e-132 S Domain of unknown function (DUF4173)
IHLHNAPA_00260 6.8e-95 ureI S AmiS/UreI family transporter
IHLHNAPA_00261 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IHLHNAPA_00262 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IHLHNAPA_00263 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IHLHNAPA_00264 2.5e-77 ureE O enzyme active site formation
IHLHNAPA_00265 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IHLHNAPA_00266 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IHLHNAPA_00267 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
IHLHNAPA_00268 2.7e-177 cbiM P PDGLE domain
IHLHNAPA_00269 1.7e-137 P cobalt transport protein
IHLHNAPA_00270 1.6e-131 cbiO P ABC transporter
IHLHNAPA_00271 1.8e-153 ET amino acid transport
IHLHNAPA_00272 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHLHNAPA_00273 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
IHLHNAPA_00274 3.8e-205 EGP Transmembrane secretion effector
IHLHNAPA_00275 1.8e-153 ET amino acid transport
IHLHNAPA_00276 7.1e-164 metQ M Belongs to the NlpA lipoprotein family
IHLHNAPA_00277 4.9e-87 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
IHLHNAPA_00278 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IHLHNAPA_00279 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
IHLHNAPA_00280 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHLHNAPA_00281 5.2e-98 metI P ABC transporter (Permease
IHLHNAPA_00282 3.9e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IHLHNAPA_00283 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
IHLHNAPA_00284 8e-94 S UPF0397 protein
IHLHNAPA_00285 0.0 ykoD P abc transporter atp-binding protein
IHLHNAPA_00286 1.2e-149 cbiQ P cobalt transport
IHLHNAPA_00287 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IHLHNAPA_00288 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
IHLHNAPA_00289 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
IHLHNAPA_00290 7.5e-242 P COG0168 Trk-type K transport systems, membrane components
IHLHNAPA_00291 3.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
IHLHNAPA_00292 8.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
IHLHNAPA_00293 3.9e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHLHNAPA_00294 3e-276 T PhoQ Sensor
IHLHNAPA_00295 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHLHNAPA_00296 1.4e-217 dnaB L Replication initiation and membrane attachment
IHLHNAPA_00297 4.4e-166 dnaI L Primosomal protein DnaI
IHLHNAPA_00298 5.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IHLHNAPA_00299 5.1e-27 L Integrase core domain protein
IHLHNAPA_00300 3.4e-50 L transposition
IHLHNAPA_00301 5.7e-23 L Transposase
IHLHNAPA_00302 1.2e-40 L transposase activity
IHLHNAPA_00303 1.5e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHLHNAPA_00304 6.5e-63 manO S protein conserved in bacteria
IHLHNAPA_00305 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
IHLHNAPA_00306 1.7e-116 manM G pts system
IHLHNAPA_00307 1.1e-181 manL 2.7.1.191 G pts system
IHLHNAPA_00308 7.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
IHLHNAPA_00309 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
IHLHNAPA_00310 1.9e-248 pbuO S permease
IHLHNAPA_00311 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
IHLHNAPA_00312 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
IHLHNAPA_00313 2.5e-220 brpA K Transcriptional
IHLHNAPA_00314 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
IHLHNAPA_00315 3.1e-212 nusA K Participates in both transcription termination and antitermination
IHLHNAPA_00316 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
IHLHNAPA_00317 1.4e-41 ylxQ J ribosomal protein
IHLHNAPA_00318 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHLHNAPA_00319 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHLHNAPA_00320 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
IHLHNAPA_00321 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
IHLHNAPA_00322 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IHLHNAPA_00323 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
IHLHNAPA_00324 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHLHNAPA_00325 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
IHLHNAPA_00326 6e-89 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
IHLHNAPA_00327 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
IHLHNAPA_00328 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IHLHNAPA_00330 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
IHLHNAPA_00331 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IHLHNAPA_00332 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IHLHNAPA_00333 7.5e-74 ylbF S Belongs to the UPF0342 family
IHLHNAPA_00334 7.1e-46 ylbG S UPF0298 protein
IHLHNAPA_00335 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
IHLHNAPA_00336 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
IHLHNAPA_00337 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
IHLHNAPA_00338 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
IHLHNAPA_00339 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
IHLHNAPA_00340 2.8e-70 acuB S IMP dehydrogenase activity
IHLHNAPA_00341 3.3e-43 acuB S IMP dehydrogenase activity
IHLHNAPA_00342 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IHLHNAPA_00343 6.3e-111 yvyE 3.4.13.9 S YigZ family
IHLHNAPA_00344 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IHLHNAPA_00345 9.9e-123 comFC S Competence protein
IHLHNAPA_00346 2.2e-91 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHLHNAPA_00353 3.5e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
IHLHNAPA_00354 6.4e-108 S Domain of unknown function (DUF1803)
IHLHNAPA_00355 1.3e-101 ygaC J Belongs to the UPF0374 family
IHLHNAPA_00356 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
IHLHNAPA_00357 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHLHNAPA_00358 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
IHLHNAPA_00359 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
IHLHNAPA_00360 1.9e-115 S Haloacid dehalogenase-like hydrolase
IHLHNAPA_00361 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
IHLHNAPA_00362 4e-72 marR K Transcriptional regulator, MarR family
IHLHNAPA_00363 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHLHNAPA_00364 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHLHNAPA_00365 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
IHLHNAPA_00366 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IHLHNAPA_00367 1.6e-126 IQ reductase
IHLHNAPA_00368 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IHLHNAPA_00369 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IHLHNAPA_00370 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHLHNAPA_00371 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IHLHNAPA_00372 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IHLHNAPA_00373 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IHLHNAPA_00374 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IHLHNAPA_00375 1.1e-202 rny D Endoribonuclease that initiates mRNA decay
IHLHNAPA_00376 1.8e-84 L Transposase
IHLHNAPA_00377 1.2e-113 fruR K transcriptional
IHLHNAPA_00378 8.4e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IHLHNAPA_00379 0.0 fruA 2.7.1.202 G phosphotransferase system
IHLHNAPA_00380 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHLHNAPA_00381 6.2e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IHLHNAPA_00383 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
IHLHNAPA_00384 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHLHNAPA_00385 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
IHLHNAPA_00386 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
IHLHNAPA_00387 6.4e-29 2.3.1.128 K acetyltransferase
IHLHNAPA_00388 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IHLHNAPA_00389 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IHLHNAPA_00390 5e-133 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHLHNAPA_00391 2.6e-64 WQ51_03320 S cog cog4835
IHLHNAPA_00392 6.4e-61 XK27_08360 S EDD domain protein, DegV family
IHLHNAPA_00393 5.5e-75 XK27_08360 S EDD domain protein, DegV family
IHLHNAPA_00394 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IHLHNAPA_00395 1.2e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IHLHNAPA_00396 0.0 yfmR S abc transporter atp-binding protein
IHLHNAPA_00397 3.3e-25 U response to pH
IHLHNAPA_00398 1e-139 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
IHLHNAPA_00399 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
IHLHNAPA_00400 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IHLHNAPA_00401 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IHLHNAPA_00402 1.9e-77 K DNA-binding transcription factor activity
IHLHNAPA_00403 0.0 lmrA1 V abc transporter atp-binding protein
IHLHNAPA_00404 0.0 lmrA2 V abc transporter atp-binding protein
IHLHNAPA_00405 2.2e-18 K Acetyltransferase (GNAT) family
IHLHNAPA_00406 3.2e-78 sptS 2.7.13.3 T Histidine kinase
IHLHNAPA_00407 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IHLHNAPA_00408 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IHLHNAPA_00409 5.3e-161 cvfB S Protein conserved in bacteria
IHLHNAPA_00410 1.6e-34 yozE S Belongs to the UPF0346 family
IHLHNAPA_00411 5.5e-120 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
IHLHNAPA_00412 1.5e-60 rlpA M LysM domain protein
IHLHNAPA_00413 1.5e-189 phoH T phosphate starvation-inducible protein PhoH
IHLHNAPA_00417 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHLHNAPA_00418 1.8e-164 K transcriptional regulator (lysR family)
IHLHNAPA_00419 1.4e-186 coiA 3.6.4.12 S Competence protein
IHLHNAPA_00420 0.0 pepF E oligoendopeptidase F
IHLHNAPA_00421 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
IHLHNAPA_00422 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
IHLHNAPA_00423 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IHLHNAPA_00424 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IHLHNAPA_00425 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IHLHNAPA_00426 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
IHLHNAPA_00427 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IHLHNAPA_00428 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
IHLHNAPA_00429 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IHLHNAPA_00430 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IHLHNAPA_00431 7.9e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
IHLHNAPA_00432 1.4e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IHLHNAPA_00433 2.2e-130 yxkH G deacetylase
IHLHNAPA_00434 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IHLHNAPA_00435 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IHLHNAPA_00436 5.5e-153 rarD S Transporter
IHLHNAPA_00437 2.2e-15 T peptidase
IHLHNAPA_00438 8.9e-14 coiA 3.6.4.12 S Competence protein
IHLHNAPA_00439 6.3e-113 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IHLHNAPA_00440 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IHLHNAPA_00441 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IHLHNAPA_00442 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHLHNAPA_00443 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
IHLHNAPA_00444 3.3e-78 atpF C ATP synthase F(0) sector subunit b
IHLHNAPA_00445 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHLHNAPA_00446 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHLHNAPA_00447 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHLHNAPA_00448 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHLHNAPA_00449 2e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IHLHNAPA_00450 1.4e-226 ftsW D Belongs to the SEDS family
IHLHNAPA_00451 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IHLHNAPA_00452 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHLHNAPA_00453 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHLHNAPA_00454 2.4e-161 holB 2.7.7.7 L dna polymerase iii
IHLHNAPA_00455 3.1e-134 yaaT S stage 0 sporulation protein
IHLHNAPA_00456 9.5e-55 yabA L Involved in initiation control of chromosome replication
IHLHNAPA_00457 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHLHNAPA_00458 5.8e-233 amt P Ammonium Transporter
IHLHNAPA_00459 1.1e-53 glnB K Belongs to the P(II) protein family
IHLHNAPA_00460 4.9e-106 mur1 NU mannosyl-glycoprotein
IHLHNAPA_00461 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
IHLHNAPA_00462 1.2e-92 nptA P COG1283 Na phosphate symporter
IHLHNAPA_00463 8e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IHLHNAPA_00464 4.9e-51
IHLHNAPA_00465 2.2e-25
IHLHNAPA_00466 1.1e-59
IHLHNAPA_00467 6.1e-63 S membrane
IHLHNAPA_00468 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IHLHNAPA_00469 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IHLHNAPA_00470 4.5e-39 ynzC S UPF0291 protein
IHLHNAPA_00471 1.8e-254 cycA E permease
IHLHNAPA_00472 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
IHLHNAPA_00473 5.8e-71 pts33BCA G pts system
IHLHNAPA_00474 2.6e-95 pts33BCA G pts system
IHLHNAPA_00475 1.5e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
IHLHNAPA_00476 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHLHNAPA_00481 1.5e-166 fhuR K transcriptional regulator (lysR family)
IHLHNAPA_00482 2.6e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IHLHNAPA_00483 8.5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHLHNAPA_00484 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHLHNAPA_00485 4.9e-227 pyrP F uracil Permease
IHLHNAPA_00486 2.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IHLHNAPA_00487 6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
IHLHNAPA_00488 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
IHLHNAPA_00489 3.4e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
IHLHNAPA_00490 2.9e-10 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHLHNAPA_00491 3.6e-35 V efflux transmembrane transporter activity
IHLHNAPA_00492 3.1e-31 V efflux transmembrane transporter activity
IHLHNAPA_00493 8.2e-28 ytrF V efflux transmembrane transporter activity
IHLHNAPA_00494 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHLHNAPA_00495 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IHLHNAPA_00496 3.4e-77 L Transposase
IHLHNAPA_00497 5.2e-39 L Transposase
IHLHNAPA_00498 1.6e-18 L Integrase core domain
IHLHNAPA_00499 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
IHLHNAPA_00500 2.8e-164 hrtB V MacB-like periplasmic core domain
IHLHNAPA_00503 3e-92 S MucBP domain
IHLHNAPA_00504 5.9e-51 M YSIRK type signal peptide
IHLHNAPA_00505 8.2e-250 M the current gene model (or a revised gene model) may contain a
IHLHNAPA_00506 1.7e-142 M the current gene model (or a revised gene model) may contain a
IHLHNAPA_00508 0.0 mdlB V abc transporter atp-binding protein
IHLHNAPA_00509 0.0 lmrA V abc transporter atp-binding protein
IHLHNAPA_00510 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IHLHNAPA_00511 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IHLHNAPA_00512 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
IHLHNAPA_00513 2.5e-132 rr02 KT response regulator
IHLHNAPA_00514 3.5e-213 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IHLHNAPA_00515 2.8e-168 V ABC transporter
IHLHNAPA_00516 5.4e-122 sagI S ABC-2 type transporter
IHLHNAPA_00517 2.4e-197 yceA S Belongs to the UPF0176 family
IHLHNAPA_00518 8e-28 XK27_00085 K Transcriptional
IHLHNAPA_00519 1.1e-22
IHLHNAPA_00520 6.5e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
IHLHNAPA_00521 9.6e-113 S VIT family
IHLHNAPA_00522 3.3e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHLHNAPA_00523 7.5e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IHLHNAPA_00524 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
IHLHNAPA_00525 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
IHLHNAPA_00526 4.4e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IHLHNAPA_00527 2.4e-07 ytjP 3.5.1.18 E Dipeptidase
IHLHNAPA_00528 3.2e-97 ET Bacterial extracellular solute-binding proteins, family 3
IHLHNAPA_00529 1.9e-59 K Acetyltransferase (GNAT) domain
IHLHNAPA_00531 7.3e-151 1.8.5.7 O Glutathione S-transferase
IHLHNAPA_00532 2.6e-170 1.8.5.7 O Glutathione S-transferase, C-terminal domain
IHLHNAPA_00533 1.3e-138 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IHLHNAPA_00534 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IHLHNAPA_00535 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
IHLHNAPA_00536 1.5e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IHLHNAPA_00537 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHLHNAPA_00538 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
IHLHNAPA_00539 2.5e-21
IHLHNAPA_00540 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHLHNAPA_00542 3.5e-07 U protein secretion
IHLHNAPA_00543 2.1e-50 U protein secretion
IHLHNAPA_00544 1.1e-11 U protein secretion
IHLHNAPA_00545 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
IHLHNAPA_00546 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IHLHNAPA_00547 5.5e-49 XK27_13030
IHLHNAPA_00548 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHLHNAPA_00549 1.6e-86 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IHLHNAPA_00550 1.4e-69 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IHLHNAPA_00551 6.1e-165 S Protein of unknown function (DUF3114)
IHLHNAPA_00552 1.2e-22 S Protein of unknown function (DUF3114)
IHLHNAPA_00553 1.5e-118 yqfA K protein, Hemolysin III
IHLHNAPA_00554 3.6e-230 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IHLHNAPA_00555 1.7e-218 mvaS 2.3.3.10 I synthase
IHLHNAPA_00556 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHLHNAPA_00557 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHLHNAPA_00558 9.7e-22
IHLHNAPA_00559 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHLHNAPA_00560 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IHLHNAPA_00561 1.3e-249 mmuP E amino acid
IHLHNAPA_00562 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
IHLHNAPA_00563 1.4e-29 S Domain of unknown function (DUF1912)
IHLHNAPA_00564 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
IHLHNAPA_00565 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IHLHNAPA_00566 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHLHNAPA_00567 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHLHNAPA_00568 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
IHLHNAPA_00569 4.8e-16 S Protein of unknown function (DUF2969)
IHLHNAPA_00572 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
IHLHNAPA_00575 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
IHLHNAPA_00576 6.1e-70 M Pfam SNARE associated Golgi protein
IHLHNAPA_00577 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
IHLHNAPA_00578 9.3e-59 S oxidoreductase
IHLHNAPA_00579 9.7e-66 S oxidoreductase
IHLHNAPA_00580 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
IHLHNAPA_00581 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IHLHNAPA_00582 0.0 clpE O Belongs to the ClpA ClpB family
IHLHNAPA_00583 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IHLHNAPA_00584 1.3e-34 ykuJ S protein conserved in bacteria
IHLHNAPA_00585 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
IHLHNAPA_00586 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHLHNAPA_00587 1.1e-78 feoA P FeoA domain protein
IHLHNAPA_00588 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IHLHNAPA_00589 1.5e-07
IHLHNAPA_00590 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IHLHNAPA_00591 2.2e-45 K sequence-specific DNA binding
IHLHNAPA_00592 2.5e-33 yugF I carboxylic ester hydrolase activity
IHLHNAPA_00593 7.5e-23 I Alpha/beta hydrolase family
IHLHNAPA_00594 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHLHNAPA_00595 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IHLHNAPA_00596 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
IHLHNAPA_00597 8.4e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHLHNAPA_00598 8.4e-63 licT K transcriptional antiterminator
IHLHNAPA_00599 6.8e-53 licT K transcriptional antiterminator
IHLHNAPA_00600 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHLHNAPA_00601 8.3e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IHLHNAPA_00602 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHLHNAPA_00603 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IHLHNAPA_00604 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IHLHNAPA_00605 5e-157 mdtG EGP Major facilitator Superfamily
IHLHNAPA_00606 2e-33 secG U Preprotein translocase subunit SecG
IHLHNAPA_00607 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IHLHNAPA_00608 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IHLHNAPA_00609 5.3e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHLHNAPA_00610 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
IHLHNAPA_00611 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
IHLHNAPA_00612 4.4e-183 ccpA K Catabolite control protein A
IHLHNAPA_00613 2.8e-28 yyaQ S YjbR
IHLHNAPA_00614 6.6e-101 yyaQ V Protein conserved in bacteria
IHLHNAPA_00615 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IHLHNAPA_00616 2.5e-77 yueI S Protein of unknown function (DUF1694)
IHLHNAPA_00617 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IHLHNAPA_00619 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IHLHNAPA_00620 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
IHLHNAPA_00621 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IHLHNAPA_00622 4.1e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IHLHNAPA_00623 6.5e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IHLHNAPA_00624 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IHLHNAPA_00625 2.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IHLHNAPA_00626 3.2e-53 yheA S Belongs to the UPF0342 family
IHLHNAPA_00627 8.8e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IHLHNAPA_00628 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IHLHNAPA_00629 2.5e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IHLHNAPA_00630 3.9e-153 pheA 4.2.1.51 E Prephenate dehydratase
IHLHNAPA_00631 1.1e-251 msrR K Transcriptional regulator
IHLHNAPA_00632 2.2e-149 ydiA P C4-dicarboxylate transporter malic acid transport protein
IHLHNAPA_00633 4.1e-203 I acyl-CoA dehydrogenase
IHLHNAPA_00634 4.5e-97 mip S hydroperoxide reductase activity
IHLHNAPA_00635 2.2e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHLHNAPA_00636 8.9e-20
IHLHNAPA_00637 3.2e-46
IHLHNAPA_00638 1.5e-18 K Cro/C1-type HTH DNA-binding domain
IHLHNAPA_00639 1.5e-44 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
IHLHNAPA_00640 9.5e-28 estA E GDSL-like Lipase/Acylhydrolase
IHLHNAPA_00641 1.1e-94
IHLHNAPA_00642 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IHLHNAPA_00643 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHLHNAPA_00644 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHLHNAPA_00645 3.7e-188 S CRISPR-associated protein Csn2 subfamily St
IHLHNAPA_00646 2.4e-147 ycgQ S TIGR03943 family
IHLHNAPA_00647 1.3e-154 XK27_03015 S permease
IHLHNAPA_00649 0.0 yhgF K Transcriptional accessory protein
IHLHNAPA_00650 9.9e-42 pspC KT PspC domain
IHLHNAPA_00651 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IHLHNAPA_00652 2.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHLHNAPA_00654 1e-67 ytxH S General stress protein
IHLHNAPA_00656 1.2e-177 yegQ O Peptidase U32
IHLHNAPA_00657 3.4e-252 yegQ O Peptidase U32
IHLHNAPA_00658 4.5e-89 bioY S biotin synthase
IHLHNAPA_00660 1.1e-33 XK27_12190 S protein conserved in bacteria
IHLHNAPA_00661 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
IHLHNAPA_00662 4.3e-12
IHLHNAPA_00663 3.1e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
IHLHNAPA_00664 0.0 L helicase
IHLHNAPA_00665 6.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IHLHNAPA_00666 1e-163 M LysM domain
IHLHNAPA_00667 1.7e-15
IHLHNAPA_00668 2.3e-175 S hydrolase
IHLHNAPA_00669 9e-113 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
IHLHNAPA_00670 8.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHLHNAPA_00671 6.7e-149 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
IHLHNAPA_00672 2.7e-27 P Hemerythrin HHE cation binding domain protein
IHLHNAPA_00673 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHLHNAPA_00674 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
IHLHNAPA_00675 9.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
IHLHNAPA_00676 1.8e-128 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IHLHNAPA_00677 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IHLHNAPA_00678 2.1e-109
IHLHNAPA_00679 4.2e-221 S SIR2-like domain
IHLHNAPA_00680 1.5e-276 S Domain of unknown function DUF87
IHLHNAPA_00681 2.5e-127 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IHLHNAPA_00682 1e-42 K Helix-turn-helix domain
IHLHNAPA_00683 1.4e-303 hsdM 2.1.1.72 V type I restriction-modification system
IHLHNAPA_00684 1.1e-90 S double-stranded DNA endodeoxyribonuclease activity
IHLHNAPA_00685 3.6e-138 spd F DNA RNA non-specific endonuclease
IHLHNAPA_00686 1.7e-91 lemA S LemA family
IHLHNAPA_00687 2.1e-131 htpX O Belongs to the peptidase M48B family
IHLHNAPA_00688 3e-73 S Psort location CytoplasmicMembrane, score
IHLHNAPA_00689 6.2e-56 S Domain of unknown function (DUF4430)
IHLHNAPA_00690 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IHLHNAPA_00691 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
IHLHNAPA_00692 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
IHLHNAPA_00693 1.1e-189 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
IHLHNAPA_00694 1.8e-113 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IHLHNAPA_00695 3.5e-91 dps P Belongs to the Dps family
IHLHNAPA_00696 1.1e-80 perR P Belongs to the Fur family
IHLHNAPA_00697 8.4e-28 yqgQ S protein conserved in bacteria
IHLHNAPA_00698 2.2e-179 glk 2.7.1.2 G Glucokinase
IHLHNAPA_00699 0.0 typA T GTP-binding protein TypA
IHLHNAPA_00701 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHLHNAPA_00702 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHLHNAPA_00703 2.9e-175 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IHLHNAPA_00704 2.3e-251 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IHLHNAPA_00705 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHLHNAPA_00706 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IHLHNAPA_00707 1.4e-96 sepF D cell septum assembly
IHLHNAPA_00708 2e-34 yggT D integral membrane protein
IHLHNAPA_00709 6.1e-143 ylmH T S4 RNA-binding domain
IHLHNAPA_00710 1.8e-135 divIVA D Cell division protein DivIVA
IHLHNAPA_00711 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHLHNAPA_00712 3.8e-16
IHLHNAPA_00713 8.4e-10
IHLHNAPA_00714 2.1e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
IHLHNAPA_00715 2e-45 rpmE2 J 50S ribosomal protein L31
IHLHNAPA_00716 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IHLHNAPA_00717 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
IHLHNAPA_00718 2.4e-155 gst O Glutathione S-transferase
IHLHNAPA_00719 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IHLHNAPA_00720 4.5e-111 tdk 2.7.1.21 F thymidine kinase
IHLHNAPA_00721 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHLHNAPA_00722 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IHLHNAPA_00723 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IHLHNAPA_00724 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IHLHNAPA_00725 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
IHLHNAPA_00726 6.6e-105 pvaA M lytic transglycosylase activity
IHLHNAPA_00727 0.0 yfiB1 V abc transporter atp-binding protein
IHLHNAPA_00728 0.0 XK27_10035 V abc transporter atp-binding protein
IHLHNAPA_00729 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
IHLHNAPA_00730 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHLHNAPA_00731 3.9e-237 dltB M Membrane protein involved in D-alanine export
IHLHNAPA_00732 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHLHNAPA_00733 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IHLHNAPA_00734 6.3e-34 L Integrase core domain protein
IHLHNAPA_00735 9.6e-32 L transposition
IHLHNAPA_00736 6.5e-54 L transposition
IHLHNAPA_00737 7.7e-19 L transposase activity
IHLHNAPA_00738 2.5e-40 L Transposase
IHLHNAPA_00739 0.0 3.6.3.8 P cation transport ATPase
IHLHNAPA_00740 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
IHLHNAPA_00742 3e-44 ymbI L transposase activity
IHLHNAPA_00743 4e-22 L Belongs to the 'phage' integrase family
IHLHNAPA_00744 1.4e-66 S tRNA_anti-like
IHLHNAPA_00745 2e-103
IHLHNAPA_00747 5e-12
IHLHNAPA_00749 2e-296 S DNA primase
IHLHNAPA_00750 3e-164 KL Phage plasmid primase P4 family
IHLHNAPA_00751 6.9e-22
IHLHNAPA_00752 9.2e-13
IHLHNAPA_00757 1.3e-17 K Cro/C1-type HTH DNA-binding domain
IHLHNAPA_00759 1.1e-220 sip L Belongs to the 'phage' integrase family
IHLHNAPA_00761 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHLHNAPA_00762 7.3e-166 metF 1.5.1.20 E reductase
IHLHNAPA_00763 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IHLHNAPA_00764 1.7e-94 panT S ECF transporter, substrate-specific component
IHLHNAPA_00765 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHLHNAPA_00766 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
IHLHNAPA_00767 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IHLHNAPA_00768 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHLHNAPA_00769 2.8e-40 T PhoQ Sensor
IHLHNAPA_00770 1.7e-43 T PhoQ Sensor
IHLHNAPA_00771 5.8e-79 T PhoQ Sensor
IHLHNAPA_00772 3.2e-76 L Transposase
IHLHNAPA_00773 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
IHLHNAPA_00774 8.9e-206 potD P spermidine putrescine ABC transporter
IHLHNAPA_00775 3.1e-268 clcA P Chloride transporter, ClC family
IHLHNAPA_00776 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
IHLHNAPA_00777 1e-102 L Helix-turn-helix domain
IHLHNAPA_00778 1.7e-162 L Integrase core domain protein
IHLHNAPA_00779 1e-29 rpsT J rRNA binding
IHLHNAPA_00780 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
IHLHNAPA_00781 8.3e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
IHLHNAPA_00782 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IHLHNAPA_00783 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
IHLHNAPA_00784 1.9e-99 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
IHLHNAPA_00785 6e-21 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IHLHNAPA_00786 2e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IHLHNAPA_00787 3.7e-54 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IHLHNAPA_00788 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IHLHNAPA_00789 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IHLHNAPA_00790 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
IHLHNAPA_00791 1e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
IHLHNAPA_00792 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IHLHNAPA_00793 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IHLHNAPA_00794 3.1e-81 ypmB S Protein conserved in bacteria
IHLHNAPA_00795 3e-215 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IHLHNAPA_00796 6.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
IHLHNAPA_00798 1.4e-07
IHLHNAPA_00799 6.3e-23
IHLHNAPA_00800 3e-13
IHLHNAPA_00801 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
IHLHNAPA_00802 9.8e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IHLHNAPA_00803 5.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
IHLHNAPA_00804 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IHLHNAPA_00805 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
IHLHNAPA_00806 7.3e-20 D nuclear chromosome segregation
IHLHNAPA_00807 7.4e-138 yejC S cyclic nucleotide-binding protein
IHLHNAPA_00808 1.2e-163 rapZ S Displays ATPase and GTPase activities
IHLHNAPA_00809 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IHLHNAPA_00810 8.7e-162 whiA K May be required for sporulation
IHLHNAPA_00811 1.2e-103 pepD E Dipeptidase
IHLHNAPA_00812 2.6e-44 pepD E Dipeptidase
IHLHNAPA_00813 1.5e-75 tspO T TspO/MBR family
IHLHNAPA_00814 1.9e-59 S Uncharacterised lipoprotein family
IHLHNAPA_00815 1.5e-59 L Transposase
IHLHNAPA_00816 1.9e-121 tnp L DDE domain
IHLHNAPA_00817 2.8e-48 S Protein of unknown function with HXXEE motif
IHLHNAPA_00818 2.1e-96 tnp L DDE domain
IHLHNAPA_00819 7.1e-28 L transposase activity
IHLHNAPA_00821 2.4e-27
IHLHNAPA_00822 9.3e-32 cspD K Cold shock protein domain
IHLHNAPA_00823 8e-42 K Cold-Shock Protein
IHLHNAPA_00824 0.0 copB 3.6.3.4 P P-type ATPase
IHLHNAPA_00825 1.6e-188 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
IHLHNAPA_00826 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IHLHNAPA_00827 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IHLHNAPA_00828 1.5e-59 cysE 2.3.1.30 E serine acetyltransferase
IHLHNAPA_00829 3.9e-56 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
IHLHNAPA_00830 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
IHLHNAPA_00831 3.7e-157 glcU U Glucose uptake
IHLHNAPA_00832 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
IHLHNAPA_00833 2.6e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
IHLHNAPA_00834 2.2e-101 XK27_10720 D peptidase activity
IHLHNAPA_00835 9.2e-297 adcA P Belongs to the bacterial solute-binding protein 9 family
IHLHNAPA_00836 1.7e-08
IHLHNAPA_00838 1.2e-172 yeiH S Membrane
IHLHNAPA_00839 5.1e-117 mur1 NU muramidase
IHLHNAPA_00840 3.2e-35 L transposase activity
IHLHNAPA_00841 4.5e-166 cpsY K Transcriptional regulator
IHLHNAPA_00842 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IHLHNAPA_00843 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
IHLHNAPA_00844 2.4e-105 artQ P ABC transporter (Permease
IHLHNAPA_00845 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHLHNAPA_00846 1.1e-158 aatB ET ABC transporter substrate-binding protein
IHLHNAPA_00847 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHLHNAPA_00848 2.1e-07
IHLHNAPA_00849 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
IHLHNAPA_00850 7.9e-112 adhP 1.1.1.1 C alcohol dehydrogenase
IHLHNAPA_00851 8.3e-49 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
IHLHNAPA_00852 3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IHLHNAPA_00853 2.9e-125 gntR1 K transcriptional
IHLHNAPA_00854 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IHLHNAPA_00855 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHLHNAPA_00856 2.4e-87 niaX
IHLHNAPA_00857 6e-91 niaR S small molecule binding protein (contains 3H domain)
IHLHNAPA_00858 8.1e-128 K DNA-binding helix-turn-helix protein
IHLHNAPA_00859 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IHLHNAPA_00860 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHLHNAPA_00861 4.1e-167 GK ROK family
IHLHNAPA_00862 8.3e-159 dprA LU DNA protecting protein DprA
IHLHNAPA_00863 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHLHNAPA_00864 1.3e-151 S TraX protein
IHLHNAPA_00865 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHLHNAPA_00866 5.3e-251 T PhoQ Sensor
IHLHNAPA_00867 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IHLHNAPA_00868 3.2e-152 XK27_05470 E Methionine synthase
IHLHNAPA_00869 7.5e-21 XK27_05470 E Methionine synthase
IHLHNAPA_00870 5e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IHLHNAPA_00871 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHLHNAPA_00872 1.3e-49 IQ Acetoin reductase
IHLHNAPA_00873 9.1e-46 IQ Acetoin reductase
IHLHNAPA_00875 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IHLHNAPA_00876 1.3e-154 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IHLHNAPA_00879 1.1e-212 pqqE C radical SAM domain protein
IHLHNAPA_00880 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
IHLHNAPA_00881 6.6e-61 EGP Major facilitator Superfamily
IHLHNAPA_00882 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IHLHNAPA_00883 5.1e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
IHLHNAPA_00884 1.9e-13
IHLHNAPA_00885 6.4e-104 V ABC transporter (Permease
IHLHNAPA_00886 4.1e-114 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IHLHNAPA_00887 1.6e-10
IHLHNAPA_00888 1.2e-97 K Transcriptional regulator, TetR family
IHLHNAPA_00889 4e-159 czcD P cation diffusion facilitator family transporter
IHLHNAPA_00890 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IHLHNAPA_00891 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IHLHNAPA_00892 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
IHLHNAPA_00893 6e-08 S Hydrolases of the alpha beta superfamily
IHLHNAPA_00894 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
IHLHNAPA_00895 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
IHLHNAPA_00898 1.2e-143 2.4.2.3 F Phosphorylase superfamily
IHLHNAPA_00899 6e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
IHLHNAPA_00900 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
IHLHNAPA_00901 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
IHLHNAPA_00903 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IHLHNAPA_00904 3.7e-190
IHLHNAPA_00905 8.1e-90 FNV0100 F Belongs to the Nudix hydrolase family
IHLHNAPA_00906 3.5e-28 3.4.13.21 I Protein conserved in bacteria
IHLHNAPA_00908 4.3e-118 S TraX protein
IHLHNAPA_00909 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
IHLHNAPA_00910 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IHLHNAPA_00911 2.1e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHLHNAPA_00912 4.7e-185 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHLHNAPA_00913 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHLHNAPA_00914 3.2e-216 mesE M HlyD family secretion protein
IHLHNAPA_00915 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IHLHNAPA_00919 2.6e-46 S Enterocin A Immunity
IHLHNAPA_00920 3.1e-10 blpU S hmm tigr01847
IHLHNAPA_00922 3.1e-16
IHLHNAPA_00923 1.2e-51
IHLHNAPA_00927 7.4e-09 S Bacteriocin class II with double-glycine leader peptide
IHLHNAPA_00928 6e-54
IHLHNAPA_00930 4.9e-16
IHLHNAPA_00931 2.3e-134 blpT
IHLHNAPA_00932 2.2e-25
IHLHNAPA_00933 7.5e-132 agrA KT phosphorelay signal transduction system
IHLHNAPA_00934 2e-138 2.7.13.3 T protein histidine kinase activity
IHLHNAPA_00937 1.8e-51 csm6 S Psort location Cytoplasmic, score
IHLHNAPA_00938 1.7e-116 csm6 S Psort location Cytoplasmic, score
IHLHNAPA_00939 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IHLHNAPA_00940 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHLHNAPA_00941 8.1e-48 nylA 3.5.1.4 J Belongs to the amidase family
IHLHNAPA_00942 7.9e-266 dtpT E transporter
IHLHNAPA_00943 1.4e-62 yecS P ABC transporter (Permease
IHLHNAPA_00944 2.3e-20 yecS P amino acid transport
IHLHNAPA_00946 5.1e-163 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IHLHNAPA_00947 5.5e-77 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
IHLHNAPA_00948 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
IHLHNAPA_00949 4e-99 yfiF3 K sequence-specific DNA binding
IHLHNAPA_00950 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IHLHNAPA_00951 1.8e-240 agcS E (Alanine) symporter
IHLHNAPA_00952 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IHLHNAPA_00953 3.5e-241 metY 2.5.1.49 E o-acetylhomoserine
IHLHNAPA_00954 3.5e-61 S haloacid dehalogenase-like hydrolase
IHLHNAPA_00955 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IHLHNAPA_00956 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
IHLHNAPA_00957 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
IHLHNAPA_00958 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
IHLHNAPA_00959 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHLHNAPA_00960 8.4e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IHLHNAPA_00961 6.7e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IHLHNAPA_00962 6.7e-44 yktA S Belongs to the UPF0223 family
IHLHNAPA_00963 1.9e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IHLHNAPA_00964 1.1e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IHLHNAPA_00965 3.3e-158 pstS P phosphate
IHLHNAPA_00966 1.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
IHLHNAPA_00967 1.2e-155 pstA P phosphate transport system permease
IHLHNAPA_00968 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHLHNAPA_00969 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHLHNAPA_00970 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
IHLHNAPA_00971 0.0 pepN 3.4.11.2 E aminopeptidase
IHLHNAPA_00972 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
IHLHNAPA_00973 9.4e-186 lplA 6.3.1.20 H Lipoate-protein ligase
IHLHNAPA_00974 4e-08
IHLHNAPA_00975 4.7e-09
IHLHNAPA_00976 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IHLHNAPA_00977 5.8e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
IHLHNAPA_00978 4.6e-25 tatA U protein secretion
IHLHNAPA_00979 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHLHNAPA_00980 2.6e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
IHLHNAPA_00981 1.5e-233 ycdB P peroxidase
IHLHNAPA_00982 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
IHLHNAPA_00983 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IHLHNAPA_00984 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IHLHNAPA_00985 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IHLHNAPA_00986 1.2e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IHLHNAPA_00987 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IHLHNAPA_00988 8.6e-187 3.5.1.28 M GBS Bsp-like repeat
IHLHNAPA_00989 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
IHLHNAPA_00990 6.4e-11 3.5.1.28 NU amidase activity
IHLHNAPA_00991 0.0 lpdA 1.8.1.4 C Dehydrogenase
IHLHNAPA_00992 6e-199 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IHLHNAPA_00993 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IHLHNAPA_00994 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IHLHNAPA_00995 3.6e-46 hpk9 2.7.13.3 T protein histidine kinase activity
IHLHNAPA_00996 3.5e-241 cas3 L CRISPR-associated helicase, Cas3
IHLHNAPA_00997 0.0 S the current gene model (or a revised gene model) may contain a frame shift
IHLHNAPA_00998 3.5e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IHLHNAPA_00999 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHLHNAPA_01000 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHLHNAPA_01001 1.2e-157 rssA S Phospholipase, patatin family
IHLHNAPA_01002 3.9e-78 estA E GDSL-like protein
IHLHNAPA_01003 2.6e-15 estA E Lysophospholipase L1 and related esterases
IHLHNAPA_01004 3.7e-293 S unusual protein kinase
IHLHNAPA_01005 4.9e-39 S granule-associated protein
IHLHNAPA_01006 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHLHNAPA_01007 2.7e-41 bglH 3.2.1.86 GT1 G beta-glucosidase activity
IHLHNAPA_01008 3.8e-96 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHLHNAPA_01009 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHLHNAPA_01010 2.2e-199 S hmm pf01594
IHLHNAPA_01011 5.8e-86 G Belongs to the phosphoglycerate mutase family
IHLHNAPA_01012 1.3e-66 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
IHLHNAPA_01013 5.4e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IHLHNAPA_01014 1.4e-96 2.7.8.12 GT2 S Glycosyltransferase like family 2
IHLHNAPA_01015 1.1e-89 tnp L DDE domain
IHLHNAPA_01016 5.9e-92 V VanZ like family
IHLHNAPA_01017 1.7e-212 glf 5.4.99.9 M UDP-galactopyranose mutase
IHLHNAPA_01018 3e-216 epsU S Polysaccharide biosynthesis protein
IHLHNAPA_01019 6.2e-239 cps1C S Polysaccharide biosynthesis protein
IHLHNAPA_01020 6.3e-86 2.7.8.12 GT2 M Glycosyltransferase like family 2
IHLHNAPA_01021 3.6e-61 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IHLHNAPA_01022 9.1e-101 M group 2 family protein
IHLHNAPA_01023 7.7e-100
IHLHNAPA_01024 1.2e-71 cps1D M Domain of unknown function (DUF4422)
IHLHNAPA_01025 5.6e-62 L Transposase DDE domain
IHLHNAPA_01026 2.7e-73 L Transposase DDE domain
IHLHNAPA_01027 2.7e-23 rgpAc GT4 M group 1 family protein
IHLHNAPA_01028 2.7e-255 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
IHLHNAPA_01029 2.1e-113 cpsD D COG0489 ATPases involved in chromosome partitioning
IHLHNAPA_01030 3.6e-107 cps4C M biosynthesis protein
IHLHNAPA_01031 3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
IHLHNAPA_01032 2.2e-252 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
IHLHNAPA_01033 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
IHLHNAPA_01034 1.5e-56 yfeJ 6.3.5.2 F glutamine amidotransferase
IHLHNAPA_01035 2.5e-43 yfeJ 6.3.5.2 F glutamine amidotransferase
IHLHNAPA_01036 3.8e-119 clcA_2 P chloride
IHLHNAPA_01037 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IHLHNAPA_01038 8.1e-41 S Protein of unknown function (DUF1697)
IHLHNAPA_01039 7.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IHLHNAPA_01040 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IHLHNAPA_01042 6.1e-22 V Glucan-binding protein C
IHLHNAPA_01043 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
IHLHNAPA_01044 7.6e-274 pepV 3.5.1.18 E Dipeptidase
IHLHNAPA_01045 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IHLHNAPA_01046 6.9e-86 XK27_03610 K Gnat family
IHLHNAPA_01047 3e-33 L COG1943 Transposase and inactivated derivatives
IHLHNAPA_01048 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHLHNAPA_01049 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IHLHNAPA_01050 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IHLHNAPA_01051 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IHLHNAPA_01052 3.9e-15 M LysM domain
IHLHNAPA_01053 2.9e-90 ebsA S Family of unknown function (DUF5322)
IHLHNAPA_01054 4.4e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IHLHNAPA_01055 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IHLHNAPA_01056 4.9e-224 G COG0457 FOG TPR repeat
IHLHNAPA_01057 1.1e-175 yubA S permease
IHLHNAPA_01058 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
IHLHNAPA_01059 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IHLHNAPA_01060 2.5e-124 ftsE D cell division ATP-binding protein FtsE
IHLHNAPA_01061 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IHLHNAPA_01062 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IHLHNAPA_01063 1.1e-180 yjjH S Calcineurin-like phosphoesterase
IHLHNAPA_01064 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IHLHNAPA_01065 0.0 pacL 3.6.3.8 P cation transport ATPase
IHLHNAPA_01066 2.6e-67 ywiB S Domain of unknown function (DUF1934)
IHLHNAPA_01067 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
IHLHNAPA_01068 9.2e-147 yidA S hydrolases of the HAD superfamily
IHLHNAPA_01069 5.5e-228 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
IHLHNAPA_01070 5e-35 F Protein of unknown function (DUF454)
IHLHNAPA_01071 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
IHLHNAPA_01072 1.9e-234 vicK 2.7.13.3 T Histidine kinase
IHLHNAPA_01073 1.7e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHLHNAPA_01074 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHLHNAPA_01075 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IHLHNAPA_01076 8e-115 gltJ P ABC transporter (Permease
IHLHNAPA_01077 2.2e-111 tcyB_2 P ABC transporter (permease)
IHLHNAPA_01078 5.5e-129 endA F DNA RNA non-specific endonuclease
IHLHNAPA_01079 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
IHLHNAPA_01080 6.5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHLHNAPA_01082 3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IHLHNAPA_01083 7.1e-15 G Domain of unknown function (DUF4832)
IHLHNAPA_01084 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHLHNAPA_01085 1.6e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IHLHNAPA_01086 3.5e-294 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHLHNAPA_01087 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
IHLHNAPA_01088 1.1e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHLHNAPA_01089 2.7e-19 WQ51_02665 S Protein of unknown function (DUF3042)
IHLHNAPA_01090 5.8e-80
IHLHNAPA_01092 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IHLHNAPA_01093 2.1e-219 XK27_05110 P chloride
IHLHNAPA_01094 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
IHLHNAPA_01095 1.3e-282 clcA P Chloride transporter, ClC family
IHLHNAPA_01096 2.3e-75 fld C Flavodoxin
IHLHNAPA_01097 2.5e-14 XK27_08880
IHLHNAPA_01098 1.8e-125 XK27_08875 O Zinc-dependent metalloprotease
IHLHNAPA_01099 3.5e-151 estA CE1 S Putative esterase
IHLHNAPA_01100 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHLHNAPA_01101 1.2e-135 XK27_08845 S abc transporter atp-binding protein
IHLHNAPA_01102 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
IHLHNAPA_01103 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
IHLHNAPA_01104 1.6e-16 S Domain of unknown function (DUF4649)
IHLHNAPA_01106 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
IHLHNAPA_01107 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
IHLHNAPA_01108 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
IHLHNAPA_01110 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IHLHNAPA_01111 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IHLHNAPA_01112 0.0 dnaE 2.7.7.7 L DNA polymerase
IHLHNAPA_01113 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
IHLHNAPA_01114 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHLHNAPA_01115 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHLHNAPA_01116 2.5e-43 ysdA L Membrane
IHLHNAPA_01117 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IHLHNAPA_01118 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IHLHNAPA_01119 1.3e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IHLHNAPA_01120 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
IHLHNAPA_01122 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IHLHNAPA_01123 2.1e-84 ypmS S Protein conserved in bacteria
IHLHNAPA_01124 1.3e-143 ypmR E lipolytic protein G-D-S-L family
IHLHNAPA_01125 1e-148 DegV S DegV family
IHLHNAPA_01126 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
IHLHNAPA_01127 3.7e-73 argR K Regulates arginine biosynthesis genes
IHLHNAPA_01128 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IHLHNAPA_01129 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IHLHNAPA_01130 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
IHLHNAPA_01131 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHLHNAPA_01134 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHLHNAPA_01135 2.9e-125 dnaD
IHLHNAPA_01136 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IHLHNAPA_01137 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHLHNAPA_01138 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
IHLHNAPA_01139 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IHLHNAPA_01140 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IHLHNAPA_01141 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IHLHNAPA_01142 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHLHNAPA_01143 5.4e-197 L transposase, IS4 family
IHLHNAPA_01144 5.6e-240 rodA D Belongs to the SEDS family
IHLHNAPA_01145 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
IHLHNAPA_01146 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IHLHNAPA_01147 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IHLHNAPA_01148 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IHLHNAPA_01149 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IHLHNAPA_01150 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IHLHNAPA_01151 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IHLHNAPA_01152 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IHLHNAPA_01153 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IHLHNAPA_01154 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHLHNAPA_01156 6.6e-31 L Integrase core domain protein
IHLHNAPA_01157 4.5e-55 L transposition
IHLHNAPA_01158 8.2e-22 L Transposase
IHLHNAPA_01159 5.2e-36 L transposase activity
IHLHNAPA_01160 1.3e-22 XK27_08085
IHLHNAPA_01161 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IHLHNAPA_01162 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
IHLHNAPA_01163 2.6e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
IHLHNAPA_01164 1.1e-121 ylfI S tigr01906
IHLHNAPA_01165 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IHLHNAPA_01166 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
IHLHNAPA_01167 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
IHLHNAPA_01170 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IHLHNAPA_01171 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
IHLHNAPA_01172 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IHLHNAPA_01173 1.1e-206 yurR 1.4.5.1 E oxidoreductase
IHLHNAPA_01174 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
IHLHNAPA_01175 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHLHNAPA_01176 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
IHLHNAPA_01177 1.7e-70 gtrA S GtrA-like protein
IHLHNAPA_01178 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHLHNAPA_01179 6e-169 ybbR S Protein conserved in bacteria
IHLHNAPA_01180 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHLHNAPA_01181 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
IHLHNAPA_01182 8.7e-150 cobQ S glutamine amidotransferase
IHLHNAPA_01183 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IHLHNAPA_01184 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
IHLHNAPA_01185 0.0 uup S abc transporter atp-binding protein
IHLHNAPA_01186 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
IHLHNAPA_01187 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
IHLHNAPA_01188 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IHLHNAPA_01189 2.8e-263 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
IHLHNAPA_01190 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHLHNAPA_01191 7.9e-39 ptsH G phosphocarrier protein Hpr
IHLHNAPA_01192 9.7e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
IHLHNAPA_01193 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
IHLHNAPA_01194 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IHLHNAPA_01195 2.2e-34 nrdH O Glutaredoxin
IHLHNAPA_01196 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHLHNAPA_01197 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHLHNAPA_01199 4.2e-71 L Transposase (IS116 IS110 IS902 family)
IHLHNAPA_01200 3.3e-26 L Transposase (IS116 IS110 IS902 family)
IHLHNAPA_01201 6.9e-165 ypuA S secreted protein
IHLHNAPA_01202 5.4e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
IHLHNAPA_01203 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHLHNAPA_01204 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IHLHNAPA_01205 3.4e-258 noxE P NADH oxidase
IHLHNAPA_01206 1.9e-294 yfmM S abc transporter atp-binding protein
IHLHNAPA_01207 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
IHLHNAPA_01208 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IHLHNAPA_01209 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
IHLHNAPA_01210 2e-86 S ECF-type riboflavin transporter, S component
IHLHNAPA_01212 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IHLHNAPA_01213 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
IHLHNAPA_01215 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHLHNAPA_01216 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHLHNAPA_01217 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHLHNAPA_01218 0.0 smc D Required for chromosome condensation and partitioning
IHLHNAPA_01219 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IHLHNAPA_01220 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHLHNAPA_01221 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHLHNAPA_01222 7.3e-82 alkD L Dna alkylation repair
IHLHNAPA_01223 2.8e-93 pat 2.3.1.183 M acetyltransferase
IHLHNAPA_01224 3e-13
IHLHNAPA_01225 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHLHNAPA_01226 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IHLHNAPA_01227 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
IHLHNAPA_01228 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
IHLHNAPA_01229 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
IHLHNAPA_01230 7.4e-26
IHLHNAPA_01231 9.3e-144 S ABC-2 family transporter protein
IHLHNAPA_01232 3.5e-33 S transport system, permease component
IHLHNAPA_01233 3.6e-97 S transport system, permease component
IHLHNAPA_01234 2.9e-79 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHLHNAPA_01235 9.4e-14 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHLHNAPA_01236 2.6e-192 desK 2.7.13.3 T Histidine kinase
IHLHNAPA_01237 1.4e-133 yvfS V ABC-2 type transporter
IHLHNAPA_01238 9.7e-158 XK27_09825 V abc transporter atp-binding protein
IHLHNAPA_01242 2.3e-213 EGP Major facilitator Superfamily
IHLHNAPA_01243 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
IHLHNAPA_01244 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
IHLHNAPA_01245 3.9e-41 3.6.1.55 F NUDIX domain
IHLHNAPA_01247 3.7e-122 S An automated process has identified a potential problem with this gene model
IHLHNAPA_01248 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
IHLHNAPA_01249 1.4e-15 liaI KT membrane
IHLHNAPA_01250 2.6e-30 liaI KT membrane
IHLHNAPA_01251 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
IHLHNAPA_01252 0.0 V ABC transporter (permease)
IHLHNAPA_01253 5.8e-135 macB2 V ABC transporter, ATP-binding protein
IHLHNAPA_01254 6.2e-166 T Histidine kinase
IHLHNAPA_01255 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHLHNAPA_01256 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IHLHNAPA_01258 3.3e-69 pbuX F xanthine permease
IHLHNAPA_01259 9.2e-119 pbuX F xanthine permease
IHLHNAPA_01260 5.3e-248 norM V Multidrug efflux pump
IHLHNAPA_01261 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHLHNAPA_01262 4.3e-234 brnQ E Component of the transport system for branched-chain amino acids
IHLHNAPA_01263 1.9e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
IHLHNAPA_01264 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
IHLHNAPA_01265 9.6e-26 csbD K CsbD-like
IHLHNAPA_01266 6.2e-228 yfnA E amino acid
IHLHNAPA_01267 1.8e-78 XK27_02070 S nitroreductase
IHLHNAPA_01268 2.1e-154 1.13.11.2 S glyoxalase
IHLHNAPA_01269 3.3e-77 ywnA K Transcriptional regulator
IHLHNAPA_01270 6.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
IHLHNAPA_01271 5.4e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHLHNAPA_01272 1.3e-111 drgA C Nitroreductase
IHLHNAPA_01273 1.7e-60 yoaK S Protein of unknown function (DUF1275)
IHLHNAPA_01275 3.1e-161 yvgN C reductase
IHLHNAPA_01276 5.6e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IHLHNAPA_01277 2.4e-09
IHLHNAPA_01278 1.6e-140 S Abortive infection C-terminus
IHLHNAPA_01279 0.0 L DEAD-like helicases superfamily
IHLHNAPA_01280 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
IHLHNAPA_01281 7.1e-278 XK27_07020 S Belongs to the UPF0371 family
IHLHNAPA_01283 1.1e-37 BP1961 P nitric oxide dioxygenase activity
IHLHNAPA_01284 1.6e-53 K response regulator
IHLHNAPA_01285 9.3e-72 S Signal peptide protein, YSIRK family
IHLHNAPA_01286 4.5e-61
IHLHNAPA_01287 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHLHNAPA_01288 2.7e-89
IHLHNAPA_01289 4e-20
IHLHNAPA_01290 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
IHLHNAPA_01291 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
IHLHNAPA_01292 5.8e-109 MA20_06410 E LysE type translocator
IHLHNAPA_01293 5.6e-08
IHLHNAPA_01294 2.7e-09
IHLHNAPA_01295 0.0 M family 8
IHLHNAPA_01296 7.2e-86 L transposition
IHLHNAPA_01297 3.1e-169 EGP Major Facilitator Superfamily
IHLHNAPA_01298 1.5e-250 I radical SAM domain protein
IHLHNAPA_01300 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IHLHNAPA_01301 1.4e-150 L Integrase core domain protein
IHLHNAPA_01302 1.8e-87 L transposase activity
IHLHNAPA_01304 3.9e-92
IHLHNAPA_01305 0.0 sbcC L ATPase involved in DNA repair
IHLHNAPA_01306 3.8e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IHLHNAPA_01307 0.0 lacL 3.2.1.23 G -beta-galactosidase
IHLHNAPA_01308 0.0 lacS G transporter
IHLHNAPA_01309 9.3e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IHLHNAPA_01310 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IHLHNAPA_01311 1.6e-293 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
IHLHNAPA_01312 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IHLHNAPA_01313 2.3e-184 galR K Transcriptional regulator
IHLHNAPA_01314 2.7e-08 L Integrase core domain protein
IHLHNAPA_01315 1.2e-25 L transposition
IHLHNAPA_01316 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IHLHNAPA_01317 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
IHLHNAPA_01318 2.5e-101 V abc transporter atp-binding protein
IHLHNAPA_01319 4.3e-40 V abc transporter atp-binding protein
IHLHNAPA_01320 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
IHLHNAPA_01321 2.3e-87 L Transposase
IHLHNAPA_01322 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IHLHNAPA_01323 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IHLHNAPA_01324 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IHLHNAPA_01325 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHLHNAPA_01328 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHLHNAPA_01329 5.8e-175 vraS 2.7.13.3 T Histidine kinase
IHLHNAPA_01330 3.7e-120 yvqF KT membrane
IHLHNAPA_01331 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IHLHNAPA_01332 2e-132 stp 3.1.3.16 T phosphatase
IHLHNAPA_01333 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHLHNAPA_01334 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHLHNAPA_01335 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHLHNAPA_01336 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
IHLHNAPA_01337 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IHLHNAPA_01338 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IHLHNAPA_01339 3.4e-149 XK27_02985 S overlaps another CDS with the same product name
IHLHNAPA_01340 2.1e-148 supH S overlaps another CDS with the same product name
IHLHNAPA_01341 8.6e-63 yvoA_1 K Transcriptional
IHLHNAPA_01342 9.8e-121 skfE V abc transporter atp-binding protein
IHLHNAPA_01343 3.3e-133 V ATPase activity
IHLHNAPA_01344 4.3e-172 oppF P Belongs to the ABC transporter superfamily
IHLHNAPA_01345 2.2e-204 oppD P Belongs to the ABC transporter superfamily
IHLHNAPA_01346 4.9e-168 amiD P ABC transporter (Permease
IHLHNAPA_01347 4.2e-278 amiC P ABC transporter (Permease
IHLHNAPA_01348 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IHLHNAPA_01349 3.5e-219 L Transposase
IHLHNAPA_01350 0.0 amiA E ABC transporter, substrate-binding protein, family 5
IHLHNAPA_01351 8.1e-45 L Transposase
IHLHNAPA_01352 4.1e-158 L COG2801 Transposase and inactivated derivatives
IHLHNAPA_01353 1e-23 oppF P Belongs to the ABC transporter superfamily
IHLHNAPA_01354 3.5e-24 oppF P Belongs to the ABC transporter superfamily
IHLHNAPA_01355 8.9e-40 tatD L Hydrolase, tatd
IHLHNAPA_01356 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
IHLHNAPA_01357 2.1e-85 L Integrase core domain protein
IHLHNAPA_01358 1.1e-23 L transposase activity
IHLHNAPA_01359 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IHLHNAPA_01360 2.8e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IHLHNAPA_01361 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHLHNAPA_01362 7.2e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
IHLHNAPA_01363 1.5e-103 yjbK S Adenylate cyclase
IHLHNAPA_01364 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHLHNAPA_01365 2.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
IHLHNAPA_01366 3.1e-59 XK27_04120 S Putative amino acid metabolism
IHLHNAPA_01367 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IHLHNAPA_01368 3.6e-131 puuD T peptidase C26
IHLHNAPA_01369 6.2e-120 radC E Belongs to the UPF0758 family
IHLHNAPA_01370 3.4e-273 rgpF M Rhamnan synthesis protein F
IHLHNAPA_01371 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IHLHNAPA_01372 6.4e-140 rgpC GM Transport permease protein
IHLHNAPA_01373 4.8e-171 rgpB GT2 M Glycosyltransferase, group 2 family protein
IHLHNAPA_01374 9.5e-222 rgpA GT4 M Domain of unknown function (DUF1972)
IHLHNAPA_01375 5e-174 S Glucosyl transferase GtrII
IHLHNAPA_01376 1.8e-28 S Glucosyl transferase GtrII
IHLHNAPA_01377 1.6e-219 GT4 M transferase activity, transferring glycosyl groups
IHLHNAPA_01378 2e-217 M Psort location CytoplasmicMembrane, score
IHLHNAPA_01379 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
IHLHNAPA_01380 9.1e-152 2.4.1.60 S Glycosyltransferase group 2 family protein
IHLHNAPA_01381 4.6e-42 S Uncharacterized conserved protein (DUF2304)
IHLHNAPA_01382 4.5e-129 arnC M group 2 family protein
IHLHNAPA_01383 1.1e-181 cpsIaJ S Glycosyltransferase like family 2
IHLHNAPA_01384 9.3e-186 S Glycosyltransferase like family 2
IHLHNAPA_01385 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
IHLHNAPA_01386 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IHLHNAPA_01387 5.3e-237 S Predicted membrane protein (DUF2142)
IHLHNAPA_01388 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
IHLHNAPA_01389 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
IHLHNAPA_01390 3.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHLHNAPA_01391 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IHLHNAPA_01392 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IHLHNAPA_01393 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
IHLHNAPA_01394 2.1e-202 arcT 2.6.1.1 E Aminotransferase
IHLHNAPA_01395 2.5e-136 ET ABC transporter
IHLHNAPA_01396 2.2e-140 ET Belongs to the bacterial solute-binding protein 3 family
IHLHNAPA_01397 2.9e-84 mutT 3.6.1.55 F Nudix family
IHLHNAPA_01398 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IHLHNAPA_01400 1.2e-55 V CAAX protease self-immunity
IHLHNAPA_01401 7.6e-32 S CAAX amino terminal protease family protein
IHLHNAPA_01402 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
IHLHNAPA_01403 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHLHNAPA_01404 2.4e-16 XK27_00735
IHLHNAPA_01405 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHLHNAPA_01407 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHLHNAPA_01410 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
IHLHNAPA_01411 6.6e-30 ycaO O OsmC-like protein
IHLHNAPA_01413 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
IHLHNAPA_01415 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
IHLHNAPA_01416 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHLHNAPA_01417 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IHLHNAPA_01418 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IHLHNAPA_01419 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
IHLHNAPA_01420 1.6e-297 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IHLHNAPA_01421 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHLHNAPA_01422 2.6e-109 3.1.3.18 S IA, variant 1
IHLHNAPA_01423 2.2e-117 lrgB M effector of murein hydrolase
IHLHNAPA_01424 7.7e-56 lrgA S Effector of murein hydrolase LrgA
IHLHNAPA_01426 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
IHLHNAPA_01427 6.3e-57 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
IHLHNAPA_01428 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHLHNAPA_01429 3.9e-104 wecD M Acetyltransferase GNAT family
IHLHNAPA_01430 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHLHNAPA_01431 9.8e-71 GK ROK family
IHLHNAPA_01432 2.4e-30 GK ROK family
IHLHNAPA_01433 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
IHLHNAPA_01434 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
IHLHNAPA_01435 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
IHLHNAPA_01436 2.3e-206 potD P spermidine putrescine ABC transporter
IHLHNAPA_01437 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
IHLHNAPA_01438 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
IHLHNAPA_01439 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IHLHNAPA_01440 7.8e-171 murB 1.3.1.98 M cell wall formation
IHLHNAPA_01441 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IHLHNAPA_01442 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IHLHNAPA_01443 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
IHLHNAPA_01444 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IHLHNAPA_01445 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
IHLHNAPA_01446 0.0 ydaO E amino acid
IHLHNAPA_01447 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IHLHNAPA_01448 4.1e-37 ylqC L Belongs to the UPF0109 family
IHLHNAPA_01449 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IHLHNAPA_01450 2.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
IHLHNAPA_01452 2e-157 xth 3.1.11.2 L exodeoxyribonuclease III
IHLHNAPA_01453 2.1e-74 S QueT transporter
IHLHNAPA_01454 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
IHLHNAPA_01455 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
IHLHNAPA_01456 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IHLHNAPA_01457 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHLHNAPA_01458 3.7e-85 ccl S cog cog4708
IHLHNAPA_01459 7.4e-164 rbn E Belongs to the UPF0761 family
IHLHNAPA_01460 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
IHLHNAPA_01461 3.3e-231 ytoI K transcriptional regulator containing CBS domains
IHLHNAPA_01462 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
IHLHNAPA_01463 4.5e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHLHNAPA_01464 0.0 comEC S Competence protein ComEC
IHLHNAPA_01465 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IHLHNAPA_01466 1.7e-142 plsC 2.3.1.51 I Acyltransferase
IHLHNAPA_01467 1.8e-140 nodB3 G deacetylase
IHLHNAPA_01468 7.1e-141 yabB 2.1.1.223 L Methyltransferase
IHLHNAPA_01469 1e-41 yazA L endonuclease containing a URI domain
IHLHNAPA_01470 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IHLHNAPA_01471 2.3e-154 corA P CorA-like protein
IHLHNAPA_01472 5.6e-62 yjqA S Bacterial PH domain
IHLHNAPA_01473 7.8e-100 thiT S Thiamine transporter
IHLHNAPA_01474 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IHLHNAPA_01475 1.9e-201 yjbB G Permeases of the major facilitator superfamily
IHLHNAPA_01476 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IHLHNAPA_01477 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
IHLHNAPA_01478 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IHLHNAPA_01482 1.1e-155 cjaA ET ABC transporter substrate-binding protein
IHLHNAPA_01483 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
IHLHNAPA_01484 1.3e-114 P ABC transporter (Permease
IHLHNAPA_01485 1e-114 papP P ABC transporter (Permease
IHLHNAPA_01486 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IHLHNAPA_01487 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
IHLHNAPA_01488 0.0 copA 3.6.3.54 P P-type ATPase
IHLHNAPA_01489 2.7e-73 copY K Copper transport repressor, CopY TcrY family
IHLHNAPA_01490 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IHLHNAPA_01491 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IHLHNAPA_01492 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
IHLHNAPA_01493 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IHLHNAPA_01494 8.7e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IHLHNAPA_01495 1.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
IHLHNAPA_01496 8.7e-259 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHLHNAPA_01497 1.3e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
IHLHNAPA_01498 8.3e-45 L Transposase
IHLHNAPA_01499 1.4e-54
IHLHNAPA_01500 0.0 ctpE P E1-E2 ATPase
IHLHNAPA_01501 1.7e-24
IHLHNAPA_01502 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHLHNAPA_01503 5.1e-47 L transposase activity
IHLHNAPA_01504 1.4e-81 K transcriptional regulator, MerR family
IHLHNAPA_01505 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
IHLHNAPA_01506 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
IHLHNAPA_01507 1.6e-63 XK27_02560 S cog cog2151
IHLHNAPA_01508 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IHLHNAPA_01509 7.7e-227 ytfP S Flavoprotein
IHLHNAPA_01511 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IHLHNAPA_01512 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
IHLHNAPA_01513 2.7e-183 ecsB U ABC transporter
IHLHNAPA_01514 2.3e-133 ecsA V abc transporter atp-binding protein
IHLHNAPA_01515 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IHLHNAPA_01516 6e-11
IHLHNAPA_01517 1.3e-56 S CD20-like family
IHLHNAPA_01518 3.2e-110
IHLHNAPA_01519 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
IHLHNAPA_01520 6.9e-206 ylbM S Belongs to the UPF0348 family
IHLHNAPA_01521 2e-140 yqeM Q Methyltransferase domain protein
IHLHNAPA_01522 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IHLHNAPA_01523 4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IHLHNAPA_01524 2.7e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IHLHNAPA_01525 3.5e-49 yhbY J RNA-binding protein
IHLHNAPA_01526 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IHLHNAPA_01527 1.8e-98 yqeG S hydrolase of the HAD superfamily
IHLHNAPA_01528 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IHLHNAPA_01529 5.8e-24
IHLHNAPA_01530 3.5e-13
IHLHNAPA_01531 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHLHNAPA_01532 1.8e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IHLHNAPA_01533 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHLHNAPA_01534 1.8e-30 M lipopolysaccharide 3-alpha-galactosyltransferase activity
IHLHNAPA_01535 1.8e-253 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHLHNAPA_01536 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHLHNAPA_01537 1.6e-154 hlpA M Belongs to the NlpA lipoprotein family
IHLHNAPA_01538 6.8e-101 pncA Q isochorismatase
IHLHNAPA_01539 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IHLHNAPA_01540 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
IHLHNAPA_01541 2.4e-75 XK27_03180 T universal stress protein
IHLHNAPA_01543 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHLHNAPA_01544 9.9e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
IHLHNAPA_01545 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
IHLHNAPA_01546 3.5e-48 L Transposase
IHLHNAPA_01547 0.0 yjcE P NhaP-type Na H and K H antiporters
IHLHNAPA_01549 2e-97 ytqB 2.1.1.176 J (SAM)-dependent
IHLHNAPA_01550 5.7e-180 yhcC S radical SAM protein
IHLHNAPA_01551 7.8e-194 ylbL T Belongs to the peptidase S16 family
IHLHNAPA_01552 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IHLHNAPA_01553 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
IHLHNAPA_01554 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IHLHNAPA_01555 1.9e-09 S Protein of unknown function (DUF4059)
IHLHNAPA_01556 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
IHLHNAPA_01557 1e-162 yxeN P ABC transporter (Permease
IHLHNAPA_01558 1.2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
IHLHNAPA_01560 1e-204 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHLHNAPA_01561 0.0 pflB 2.3.1.54 C formate acetyltransferase'
IHLHNAPA_01562 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
IHLHNAPA_01563 1.5e-83 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHLHNAPA_01564 1.7e-30 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
IHLHNAPA_01565 6.5e-31 D nuclear chromosome segregation
IHLHNAPA_01566 4.1e-33 L DNA integration
IHLHNAPA_01567 3.2e-124 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
IHLHNAPA_01568 1.5e-127 ybbM S transport system, permease component
IHLHNAPA_01569 1.2e-117 ybbL S abc transporter atp-binding protein
IHLHNAPA_01570 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
IHLHNAPA_01571 4.6e-140 cppA E CppA N-terminal
IHLHNAPA_01572 5e-44 V CAAX protease self-immunity
IHLHNAPA_01573 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
IHLHNAPA_01574 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IHLHNAPA_01576 0.0 mdlB V abc transporter atp-binding protein
IHLHNAPA_01577 0.0 mdlA V abc transporter atp-binding protein
IHLHNAPA_01579 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
IHLHNAPA_01580 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IHLHNAPA_01581 2.3e-72 yutD J protein conserved in bacteria
IHLHNAPA_01582 1.9e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IHLHNAPA_01584 6.1e-220 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IHLHNAPA_01585 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHLHNAPA_01586 0.0 ftsI 3.4.16.4 M penicillin-binding protein
IHLHNAPA_01587 4.3e-47 ftsL D cell division protein FtsL
IHLHNAPA_01588 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IHLHNAPA_01589 1.6e-65
IHLHNAPA_01590 7.4e-27
IHLHNAPA_01591 2.6e-30
IHLHNAPA_01593 9.7e-32 yhaI J Protein of unknown function (DUF805)
IHLHNAPA_01594 1.1e-12 D nuclear chromosome segregation
IHLHNAPA_01595 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHLHNAPA_01596 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHLHNAPA_01597 3.1e-287 XK27_00765
IHLHNAPA_01598 1.4e-133 ecsA_2 V abc transporter atp-binding protein
IHLHNAPA_01599 2.5e-47 S Protein of unknown function (DUF554)
IHLHNAPA_01600 8.5e-32 S Protein of unknown function (DUF554)
IHLHNAPA_01601 1.6e-11 S Protein of unknown function (DUF554)
IHLHNAPA_01602 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IHLHNAPA_01603 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IHLHNAPA_01604 2.6e-121 liaI S membrane
IHLHNAPA_01605 5.2e-75 XK27_02470 K LytTr DNA-binding domain
IHLHNAPA_01606 3.6e-66 KT response to antibiotic
IHLHNAPA_01607 2.6e-80 yebC M Membrane
IHLHNAPA_01608 2.9e-18 yebC M Membrane
IHLHNAPA_01609 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
IHLHNAPA_01610 8.5e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IHLHNAPA_01611 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHLHNAPA_01612 2e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHLHNAPA_01613 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IHLHNAPA_01614 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHLHNAPA_01615 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IHLHNAPA_01616 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IHLHNAPA_01618 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
IHLHNAPA_01619 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
IHLHNAPA_01620 0.0 scrA 2.7.1.211 G pts system
IHLHNAPA_01621 5.4e-291 scrB 3.2.1.26 GH32 G invertase
IHLHNAPA_01622 7.5e-180 scrR K Transcriptional
IHLHNAPA_01623 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHLHNAPA_01624 3.4e-62 yqhY S protein conserved in bacteria
IHLHNAPA_01625 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHLHNAPA_01626 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
IHLHNAPA_01627 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
IHLHNAPA_01629 2e-09 V 'abc transporter, ATP-binding protein
IHLHNAPA_01632 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IHLHNAPA_01633 2e-169 corA P COG0598 Mg2 and Co2 transporters
IHLHNAPA_01634 3.1e-124 XK27_01040 S Pfam PF06570
IHLHNAPA_01636 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IHLHNAPA_01637 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHLHNAPA_01638 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
IHLHNAPA_01639 3.6e-41 XK27_05745
IHLHNAPA_01640 2.3e-228 mutY L A G-specific adenine glycosylase
IHLHNAPA_01645 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHLHNAPA_01646 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHLHNAPA_01647 1e-93 cvpA S toxin biosynthetic process
IHLHNAPA_01648 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IHLHNAPA_01649 1e-159 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHLHNAPA_01650 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IHLHNAPA_01651 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IHLHNAPA_01652 1.2e-47 azlD E branched-chain amino acid
IHLHNAPA_01653 6e-46 azlC E AzlC protein
IHLHNAPA_01654 1.7e-46 azlC E AzlC protein
IHLHNAPA_01655 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHLHNAPA_01656 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IHLHNAPA_01657 2.8e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
IHLHNAPA_01658 2.5e-33 ykzG S Belongs to the UPF0356 family
IHLHNAPA_01659 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHLHNAPA_01660 2.7e-40 pscB M CHAP domain protein
IHLHNAPA_01661 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
IHLHNAPA_01662 8.5e-63 glnR K Transcriptional regulator
IHLHNAPA_01663 1.3e-87 S Fusaric acid resistance protein-like
IHLHNAPA_01664 3e-13
IHLHNAPA_01665 3.1e-22
IHLHNAPA_01666 3.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IHLHNAPA_01667 1e-51 L Transposase
IHLHNAPA_01668 7.4e-23 L Transposase
IHLHNAPA_01669 9.4e-47 L transposition
IHLHNAPA_01670 4.2e-86 L Integrase core domain protein
IHLHNAPA_01671 4.3e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IHLHNAPA_01672 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHLHNAPA_01673 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IHLHNAPA_01674 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHLHNAPA_01675 1.1e-142 purR 2.4.2.7 F operon repressor
IHLHNAPA_01676 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
IHLHNAPA_01677 6.9e-173 rmuC S RmuC domain protein
IHLHNAPA_01678 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
IHLHNAPA_01679 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IHLHNAPA_01680 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IHLHNAPA_01682 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IHLHNAPA_01683 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IHLHNAPA_01684 4.5e-143 tatD L Hydrolase, tatd
IHLHNAPA_01685 2.5e-74 yccU S CoA-binding protein
IHLHNAPA_01686 4.8e-51 trxA O Belongs to the thioredoxin family
IHLHNAPA_01687 7.8e-143 S Macro domain protein
IHLHNAPA_01688 3.1e-10 L thioesterase
IHLHNAPA_01689 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
IHLHNAPA_01692 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IHLHNAPA_01693 1e-33 L Transposase
IHLHNAPA_01694 1e-13 rpmH J Ribosomal protein L34
IHLHNAPA_01695 1e-185 jag S RNA-binding protein
IHLHNAPA_01696 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHLHNAPA_01697 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IHLHNAPA_01698 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
IHLHNAPA_01699 9.9e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IHLHNAPA_01700 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHLHNAPA_01701 9.5e-63 amiA E transmembrane transport
IHLHNAPA_01702 2e-41 amiA E transmembrane transport
IHLHNAPA_01703 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
IHLHNAPA_01704 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
IHLHNAPA_01705 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IHLHNAPA_01706 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IHLHNAPA_01707 9.2e-51 S Protein of unknown function (DUF3397)
IHLHNAPA_01708 6.6e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
IHLHNAPA_01709 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
IHLHNAPA_01710 1.5e-10 WQ51_05710 S Mitochondrial biogenesis AIM24
IHLHNAPA_01711 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHLHNAPA_01712 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
IHLHNAPA_01713 2.4e-19 XK27_09620 S FMN reductase (NADPH) activity
IHLHNAPA_01714 3.1e-75 XK27_09620 S reductase
IHLHNAPA_01715 5.8e-61 XK27_09615 C reductase
IHLHNAPA_01716 3.3e-135 XK27_09615 C reductase
IHLHNAPA_01717 8.1e-91 fnt P Formate nitrite transporter
IHLHNAPA_01718 6.5e-83 XK27_08585 S Psort location CytoplasmicMembrane, score
IHLHNAPA_01719 7.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IHLHNAPA_01720 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IHLHNAPA_01721 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
IHLHNAPA_01722 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHLHNAPA_01723 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IHLHNAPA_01724 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IHLHNAPA_01725 6e-48 S glycolate biosynthetic process
IHLHNAPA_01726 1.5e-64 S phosphatase activity
IHLHNAPA_01727 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
IHLHNAPA_01730 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IHLHNAPA_01731 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHLHNAPA_01732 8.3e-37 yeeD O sulfur carrier activity
IHLHNAPA_01733 7.8e-191 yeeE S Sulphur transport
IHLHNAPA_01734 1.8e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHLHNAPA_01735 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IHLHNAPA_01736 1.2e-08 S Domain of unknown function (DUF4651)
IHLHNAPA_01737 5.7e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IHLHNAPA_01738 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHLHNAPA_01739 3.9e-111 S CAAX amino terminal protease family protein
IHLHNAPA_01741 5e-67 V CAAX protease self-immunity
IHLHNAPA_01742 1.4e-33 V CAAX protease self-immunity
IHLHNAPA_01743 8.8e-27 lanR K sequence-specific DNA binding
IHLHNAPA_01744 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHLHNAPA_01745 2.2e-176 ytxK 2.1.1.72 L DNA methylase
IHLHNAPA_01746 5.8e-12 comGF U Putative Competence protein ComGF
IHLHNAPA_01747 1.3e-70 comGF U Competence protein ComGF
IHLHNAPA_01748 3.2e-15 NU Type II secretory pathway pseudopilin
IHLHNAPA_01749 3e-57 cglD NU Competence protein
IHLHNAPA_01750 8.5e-43 comGC U Required for transformation and DNA binding
IHLHNAPA_01751 5.4e-153 cglB U protein transport across the cell outer membrane
IHLHNAPA_01752 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHLHNAPA_01753 1e-68 S cog cog4699
IHLHNAPA_01754 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHLHNAPA_01755 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHLHNAPA_01756 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHLHNAPA_01757 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHLHNAPA_01758 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IHLHNAPA_01759 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
IHLHNAPA_01760 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
IHLHNAPA_01761 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IHLHNAPA_01762 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IHLHNAPA_01763 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
IHLHNAPA_01764 1.8e-57 asp S cog cog1302
IHLHNAPA_01765 3.2e-226 norN V Mate efflux family protein
IHLHNAPA_01766 1.9e-278 thrC 4.2.3.1 E Threonine synthase
IHLHNAPA_01767 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IHLHNAPA_01768 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
IHLHNAPA_01769 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IHLHNAPA_01770 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IHLHNAPA_01771 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
IHLHNAPA_01772 0.0 pepO 3.4.24.71 O Peptidase family M13
IHLHNAPA_01773 1.8e-37 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IHLHNAPA_01774 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IHLHNAPA_01775 5e-65 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IHLHNAPA_01776 1.4e-54 treB 2.7.1.201 G PTS System
IHLHNAPA_01777 5.8e-21 treR K DNA-binding transcription factor activity
IHLHNAPA_01778 8.6e-87 treR K trehalose operon
IHLHNAPA_01779 7.4e-95 ywlG S Belongs to the UPF0340 family
IHLHNAPA_01782 2.7e-13 L PFAM Integrase, catalytic core
IHLHNAPA_01783 2.3e-114 L PFAM Integrase, catalytic core
IHLHNAPA_01784 3.3e-46 K Putative DNA-binding domain
IHLHNAPA_01785 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
IHLHNAPA_01786 1e-125 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IHLHNAPA_01787 9.3e-135 HJ the current gene model (or a revised gene model) may contain a frame shift
IHLHNAPA_01790 1.5e-30
IHLHNAPA_01791 4e-26
IHLHNAPA_01792 1.2e-39 isp2 S pathogenesis
IHLHNAPA_01793 4.4e-15
IHLHNAPA_01795 8.8e-131 L DNA integration
IHLHNAPA_01796 5.3e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
IHLHNAPA_01798 1.1e-109 6.3.2.2 H ergothioneine biosynthetic process
IHLHNAPA_01799 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
IHLHNAPA_01800 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
IHLHNAPA_01801 2.7e-13 L PFAM Integrase, catalytic core
IHLHNAPA_01802 1.1e-95 L PFAM Integrase, catalytic core
IHLHNAPA_01803 3.3e-62 rplQ J ribosomal protein l17
IHLHNAPA_01804 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHLHNAPA_01805 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHLHNAPA_01806 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHLHNAPA_01807 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IHLHNAPA_01808 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IHLHNAPA_01809 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IHLHNAPA_01810 5.1e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IHLHNAPA_01811 1.3e-57 rplO J binds to the 23S rRNA
IHLHNAPA_01812 2.5e-23 rpmD J ribosomal protein l30
IHLHNAPA_01813 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHLHNAPA_01814 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IHLHNAPA_01815 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHLHNAPA_01816 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHLHNAPA_01817 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHLHNAPA_01818 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHLHNAPA_01819 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IHLHNAPA_01820 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHLHNAPA_01821 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHLHNAPA_01822 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
IHLHNAPA_01823 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHLHNAPA_01824 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHLHNAPA_01825 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IHLHNAPA_01826 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHLHNAPA_01827 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHLHNAPA_01828 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IHLHNAPA_01829 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
IHLHNAPA_01830 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHLHNAPA_01831 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
IHLHNAPA_01832 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IHLHNAPA_01833 0.0 XK27_09800 I Acyltransferase
IHLHNAPA_01834 1.7e-35 XK27_09805 S MORN repeat protein
IHLHNAPA_01835 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHLHNAPA_01836 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHLHNAPA_01837 1.2e-83 adk 2.7.4.3 F topology modulation protein
IHLHNAPA_01838 3.1e-172 yxaM EGP Major facilitator Superfamily
IHLHNAPA_01839 7.4e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
IHLHNAPA_01840 2.2e-26 L Transposase
IHLHNAPA_01842 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
IHLHNAPA_01843 0.0 KLT serine threonine protein kinase
IHLHNAPA_01844 2.1e-280 V ABC transporter
IHLHNAPA_01845 1.4e-127 Z012_04635 K sequence-specific DNA binding
IHLHNAPA_01847 6.3e-16 C Radical SAM
IHLHNAPA_01848 3.4e-191 C Radical SAM
IHLHNAPA_01849 4.3e-286 V ABC transporter transmembrane region
IHLHNAPA_01850 2.5e-89 K sequence-specific DNA binding
IHLHNAPA_01851 1e-36 L Replication initiation factor
IHLHNAPA_01852 1.4e-107 L Replication initiation factor
IHLHNAPA_01853 1.9e-18 S Domain of unknown function (DUF3173)
IHLHNAPA_01854 8.2e-151 int L Belongs to the 'phage' integrase family
IHLHNAPA_01855 3.4e-51 int L Phage integrase family
IHLHNAPA_01857 4.4e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
IHLHNAPA_01858 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IHLHNAPA_01859 2.8e-44 yrzL S Belongs to the UPF0297 family
IHLHNAPA_01860 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHLHNAPA_01861 4.2e-44 yrzB S Belongs to the UPF0473 family
IHLHNAPA_01862 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
IHLHNAPA_01863 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IHLHNAPA_01864 7.5e-14
IHLHNAPA_01865 2.6e-91 XK27_10930 K acetyltransferase
IHLHNAPA_01866 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IHLHNAPA_01867 1.8e-147 yaaA S Belongs to the UPF0246 family
IHLHNAPA_01868 2.4e-167 XK27_01785 S cog cog1284
IHLHNAPA_01869 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IHLHNAPA_01871 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
IHLHNAPA_01872 5.7e-52 metE 2.1.1.14 E Methionine synthase
IHLHNAPA_01873 7.6e-64 metE 2.1.1.14 E Methionine synthase
IHLHNAPA_01874 9.2e-36 metE 2.1.1.14 E Methionine synthase
IHLHNAPA_01875 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IHLHNAPA_01876 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IHLHNAPA_01878 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
IHLHNAPA_01879 2.7e-95 S Hydrophobic domain protein
IHLHNAPA_01881 3.7e-27 S Membrane
IHLHNAPA_01882 3.1e-101
IHLHNAPA_01883 1.8e-23 S Small integral membrane protein
IHLHNAPA_01884 1.1e-71 M Protein conserved in bacteria
IHLHNAPA_01885 4.9e-12 K CsbD-like
IHLHNAPA_01886 3.5e-97 nudL L hydrolase
IHLHNAPA_01887 3.4e-13 nudL L hydrolase
IHLHNAPA_01888 4e-19 K negative regulation of transcription, DNA-templated
IHLHNAPA_01889 1.7e-23 K negative regulation of transcription, DNA-templated
IHLHNAPA_01891 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
IHLHNAPA_01892 1.8e-88 S Putative adhesin
IHLHNAPA_01893 3.9e-161 XK27_06930 V domain protein
IHLHNAPA_01894 6.4e-96 XK27_06935 K transcriptional regulator
IHLHNAPA_01895 2e-53 ypaA S membrane
IHLHNAPA_01896 3e-08
IHLHNAPA_01897 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHLHNAPA_01898 2.4e-47 veg S Biofilm formation stimulator VEG
IHLHNAPA_01899 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IHLHNAPA_01900 3.9e-70 rplI J binds to the 23S rRNA
IHLHNAPA_01901 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IHLHNAPA_01902 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IHLHNAPA_01903 4.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IHLHNAPA_01904 0.0 S Bacterial membrane protein, YfhO
IHLHNAPA_01905 4.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
IHLHNAPA_01906 1.7e-91 lytE M LysM domain protein
IHLHNAPA_01907 2.3e-237 L Transposase
IHLHNAPA_01908 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHLHNAPA_01909 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHLHNAPA_01910 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHLHNAPA_01911 1.2e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHLHNAPA_01912 6.3e-138 ymfM S sequence-specific DNA binding
IHLHNAPA_01913 3.1e-242 ymfH S Peptidase M16
IHLHNAPA_01914 1.8e-234 ymfF S Peptidase M16
IHLHNAPA_01915 1.6e-45 yaaA S S4 domain protein YaaA
IHLHNAPA_01916 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHLHNAPA_01917 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IHLHNAPA_01918 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IHLHNAPA_01919 5.4e-153 yvjA S membrane
IHLHNAPA_01920 3.3e-305 ybiT S abc transporter atp-binding protein
IHLHNAPA_01921 0.0 XK27_10405 S Bacterial membrane protein YfhO
IHLHNAPA_01925 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
IHLHNAPA_01926 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHLHNAPA_01927 1.1e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
IHLHNAPA_01928 8.5e-134 parB K Belongs to the ParB family
IHLHNAPA_01929 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHLHNAPA_01930 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IHLHNAPA_01931 1.1e-29 yyzM S Protein conserved in bacteria
IHLHNAPA_01932 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IHLHNAPA_01933 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IHLHNAPA_01934 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHLHNAPA_01935 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IHLHNAPA_01936 2.7e-61 divIC D Septum formation initiator
IHLHNAPA_01938 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
IHLHNAPA_01939 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IHLHNAPA_01940 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IHLHNAPA_01941 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHLHNAPA_01942 4e-136 L Transposase
IHLHNAPA_01943 2.5e-92 L Transposase
IHLHNAPA_01944 3e-51 L transposition
IHLHNAPA_01945 2.4e-214 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IHLHNAPA_01946 1.9e-225 nodC 2.4.1.212 GT2 M Chitin synthase
IHLHNAPA_01947 2.1e-128 tnp L DDE domain
IHLHNAPA_01948 2.4e-178 L transposase, IS4 family
IHLHNAPA_01949 3e-13 mesE M Transport protein ComB
IHLHNAPA_01950 0.0 P Belongs to the ABC transporter superfamily
IHLHNAPA_01951 1.8e-141 dppC P N-terminal TM domain of oligopeptide transport permease C
IHLHNAPA_01952 2.8e-188 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHLHNAPA_01953 0.0 ddpA E ABC transporter substrate-binding protein
IHLHNAPA_01955 1.9e-57 L Transposase
IHLHNAPA_01956 6.2e-128 tnp L DDE domain
IHLHNAPA_01957 1.1e-236 L Helix-turn-helix domain of transposase family ISL3
IHLHNAPA_01958 5.4e-92 3.6.4.12 K Divergent AAA domain protein
IHLHNAPA_01959 5.9e-24 3.6.4.12
IHLHNAPA_01960 7.7e-112 EGP Major facilitator Superfamily
IHLHNAPA_01961 4.7e-56 EGP Major facilitator Superfamily
IHLHNAPA_01963 4.1e-181 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)