ORF_ID e_value Gene_name EC_number CAZy COGs Description
DEMGKBKK_00001 1e-63 L Transposase
DEMGKBKK_00002 6.7e-23
DEMGKBKK_00003 9.4e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DEMGKBKK_00004 2.4e-66 2.4.1.83 GT2 S GtrA-like protein
DEMGKBKK_00005 8.9e-170 yfdH GT2 M Glycosyltransferase like family 2
DEMGKBKK_00006 1e-57 S Bacterial membrane protein, YfhO
DEMGKBKK_00007 1e-85 S Bacterial membrane protein, YfhO
DEMGKBKK_00008 1.4e-93 S Bacterial membrane protein, YfhO
DEMGKBKK_00009 1e-101
DEMGKBKK_00010 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DEMGKBKK_00011 4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DEMGKBKK_00012 2.2e-125 S Haloacid dehalogenase-like hydrolase
DEMGKBKK_00013 3e-113 radC L DNA repair protein
DEMGKBKK_00014 1.6e-172 mreB D cell shape determining protein MreB
DEMGKBKK_00015 4.3e-147 mreC M Involved in formation and maintenance of cell shape
DEMGKBKK_00016 4.9e-96 mreD
DEMGKBKK_00017 2.5e-12 S Protein of unknown function (DUF4044)
DEMGKBKK_00018 1.9e-53 S Protein of unknown function (DUF3397)
DEMGKBKK_00019 1.7e-84 L COG2826 Transposase and inactivated derivatives, IS30 family
DEMGKBKK_00020 1.2e-17 L Transposase and inactivated derivatives IS30 family
DEMGKBKK_00021 3.1e-69 L COG2826 Transposase and inactivated derivatives, IS30 family
DEMGKBKK_00022 1.8e-77 mraZ K Belongs to the MraZ family
DEMGKBKK_00023 3.4e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DEMGKBKK_00024 9.1e-54 ftsL D Cell division protein FtsL
DEMGKBKK_00025 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
DEMGKBKK_00026 2.3e-176 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DEMGKBKK_00027 2.8e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DEMGKBKK_00028 2.2e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DEMGKBKK_00029 9.8e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DEMGKBKK_00030 5.7e-234 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DEMGKBKK_00031 1.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DEMGKBKK_00032 4.8e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DEMGKBKK_00033 9e-47 yggT S YGGT family
DEMGKBKK_00034 8.2e-148 ylmH S S4 domain protein
DEMGKBKK_00035 6.1e-95 gpsB D DivIVA domain protein
DEMGKBKK_00036 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DEMGKBKK_00037 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
DEMGKBKK_00038 6.3e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
DEMGKBKK_00039 4.6e-38
DEMGKBKK_00040 3.8e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DEMGKBKK_00041 3e-215 iscS 2.8.1.7 E Aminotransferase class V
DEMGKBKK_00042 1.4e-56 XK27_04120 S Putative amino acid metabolism
DEMGKBKK_00043 2.7e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DEMGKBKK_00044 1.2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DEMGKBKK_00045 3e-100 S Repeat protein
DEMGKBKK_00046 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DEMGKBKK_00047 4.8e-108 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DEMGKBKK_00048 2.1e-29 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
DEMGKBKK_00049 2.3e-193 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DEMGKBKK_00050 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEMGKBKK_00051 1.2e-32 ykzG S Belongs to the UPF0356 family
DEMGKBKK_00052 1.5e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DEMGKBKK_00053 0.0 typA T GTP-binding protein TypA
DEMGKBKK_00054 1.4e-207 ftsW D Belongs to the SEDS family
DEMGKBKK_00055 4.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
DEMGKBKK_00056 1.9e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
DEMGKBKK_00057 2.7e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DEMGKBKK_00058 6.4e-193 ylbL T Belongs to the peptidase S16 family
DEMGKBKK_00059 7.3e-84 comEA L Competence protein ComEA
DEMGKBKK_00060 0.0 comEC S Competence protein ComEC
DEMGKBKK_00061 2.2e-171 holA 2.7.7.7 L DNA polymerase III delta subunit
DEMGKBKK_00062 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
DEMGKBKK_00063 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DEMGKBKK_00064 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DEMGKBKK_00065 5.4e-150
DEMGKBKK_00066 4.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DEMGKBKK_00067 1.3e-209 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DEMGKBKK_00068 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DEMGKBKK_00069 6.4e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
DEMGKBKK_00070 2.4e-273 yjeM E Amino Acid
DEMGKBKK_00071 3.5e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DEMGKBKK_00072 1.6e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
DEMGKBKK_00073 3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DEMGKBKK_00074 3.6e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DEMGKBKK_00075 4e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DEMGKBKK_00076 7.8e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DEMGKBKK_00077 2.1e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DEMGKBKK_00078 2e-214 aspC 2.6.1.1 E Aminotransferase
DEMGKBKK_00079 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DEMGKBKK_00080 1.5e-203 pbpX1 V Beta-lactamase
DEMGKBKK_00081 1.5e-55 3.6.1.55 F NUDIX domain
DEMGKBKK_00082 8.4e-301 I Protein of unknown function (DUF2974)
DEMGKBKK_00083 3.2e-28 C FMN_bind
DEMGKBKK_00084 4e-79
DEMGKBKK_00085 7e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
DEMGKBKK_00086 6.3e-168 S Aldo keto reductase
DEMGKBKK_00087 2.5e-288 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEMGKBKK_00088 4.4e-115 K UTRA domain
DEMGKBKK_00089 1.9e-53 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
DEMGKBKK_00090 4.7e-58 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
DEMGKBKK_00091 4e-79
DEMGKBKK_00092 2.8e-241 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMGKBKK_00093 1.2e-15 gepA K Protein of unknown function (DUF4065)
DEMGKBKK_00094 6.7e-69 S Domain of unknown function (DUF3284)
DEMGKBKK_00095 3.2e-299 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEMGKBKK_00096 1.1e-122 gmuR K UTRA
DEMGKBKK_00097 1.2e-38
DEMGKBKK_00098 3.7e-260 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMGKBKK_00099 1.9e-277 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEMGKBKK_00100 6.1e-149 ypbG 2.7.1.2 GK ROK family
DEMGKBKK_00101 2.1e-85 C nitroreductase
DEMGKBKK_00102 8.6e-65 S Domain of unknown function (DUF4767)
DEMGKBKK_00103 6.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DEMGKBKK_00104 6.6e-132 yitS S Uncharacterised protein, DegV family COG1307
DEMGKBKK_00105 7.2e-98 3.6.1.27 I Acid phosphatase homologues
DEMGKBKK_00106 2.2e-82 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DEMGKBKK_00107 1e-58 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DEMGKBKK_00109 5.4e-248 yifK E Amino acid permease
DEMGKBKK_00110 7e-186 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DEMGKBKK_00111 4.4e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DEMGKBKK_00112 2.1e-15 ps301 K sequence-specific DNA binding
DEMGKBKK_00113 0.0 aha1 P E1-E2 ATPase
DEMGKBKK_00114 8.2e-162 metQ1 P Belongs to the nlpA lipoprotein family
DEMGKBKK_00115 3.4e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DEMGKBKK_00116 6.4e-88 metI P ABC transporter permease
DEMGKBKK_00117 1.7e-34
DEMGKBKK_00118 2e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DEMGKBKK_00119 1.1e-253 frdC 1.3.5.4 C FAD binding domain
DEMGKBKK_00120 2e-161 L Transposase
DEMGKBKK_00121 2e-233 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DEMGKBKK_00123 9.7e-43 M domain protein
DEMGKBKK_00124 1.1e-07 UW LPXTG-motif cell wall anchor domain protein
DEMGKBKK_00125 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DEMGKBKK_00126 1.3e-11 fhaB M Rib/alpha-like repeat
DEMGKBKK_00127 6.1e-80
DEMGKBKK_00128 2.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
DEMGKBKK_00129 4.1e-37 P Sodium:sulfate symporter transmembrane region
DEMGKBKK_00130 4.2e-152 ydjP I Alpha/beta hydrolase family
DEMGKBKK_00131 1.7e-193 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
DEMGKBKK_00132 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
DEMGKBKK_00133 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
DEMGKBKK_00134 1.8e-88 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
DEMGKBKK_00135 7.9e-67 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
DEMGKBKK_00136 1.9e-98 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
DEMGKBKK_00137 2.8e-91
DEMGKBKK_00138 2.9e-77 M1-431 S Protein of unknown function (DUF1706)
DEMGKBKK_00139 1.3e-87 L Transposase
DEMGKBKK_00140 7.9e-120 L Transposase
DEMGKBKK_00141 7.9e-71 yeaL S Protein of unknown function (DUF441)
DEMGKBKK_00142 9e-14
DEMGKBKK_00143 6.8e-128 cbiQ P cobalt transport
DEMGKBKK_00144 0.0 ykoD P ABC transporter, ATP-binding protein
DEMGKBKK_00145 1.3e-94 S UPF0397 protein
DEMGKBKK_00146 1.4e-65 S Domain of unknown function DUF1828
DEMGKBKK_00147 4.2e-53
DEMGKBKK_00148 1.3e-168 citR K Putative sugar-binding domain
DEMGKBKK_00149 4.3e-242 yjjP S Putative threonine/serine exporter
DEMGKBKK_00150 1.8e-95 yxkA S Phosphatidylethanolamine-binding protein
DEMGKBKK_00151 6.4e-26
DEMGKBKK_00153 2.3e-29 M domain protein
DEMGKBKK_00154 5.7e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DEMGKBKK_00155 7.2e-175 prmA J Ribosomal protein L11 methyltransferase
DEMGKBKK_00156 1.5e-59
DEMGKBKK_00157 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DEMGKBKK_00158 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DEMGKBKK_00159 1.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
DEMGKBKK_00160 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DEMGKBKK_00161 6.3e-221 patA 2.6.1.1 E Aminotransferase
DEMGKBKK_00162 7.3e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DEMGKBKK_00163 1.4e-19 S reductase
DEMGKBKK_00164 6.8e-110 S reductase
DEMGKBKK_00165 2.4e-139 yxeH S hydrolase
DEMGKBKK_00166 7.8e-16 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEMGKBKK_00167 3.1e-31 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEMGKBKK_00168 1.6e-89 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEMGKBKK_00169 6.6e-246 yfnA E Amino Acid
DEMGKBKK_00170 1.9e-44 dedA 3.1.3.1 S SNARE associated Golgi protein
DEMGKBKK_00171 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DEMGKBKK_00172 3.6e-241 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DEMGKBKK_00173 0.0 oatA I Acyltransferase
DEMGKBKK_00174 2.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DEMGKBKK_00175 6.1e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DEMGKBKK_00176 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
DEMGKBKK_00177 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DEMGKBKK_00178 1.7e-303 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
DEMGKBKK_00179 2.5e-22 S Protein of unknown function (DUF2929)
DEMGKBKK_00180 0.0 dnaE 2.7.7.7 L DNA polymerase
DEMGKBKK_00181 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
DEMGKBKK_00182 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DEMGKBKK_00183 1.8e-162 cvfB S S1 domain
DEMGKBKK_00184 4e-167 xerD D recombinase XerD
DEMGKBKK_00185 1.2e-58 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DEMGKBKK_00186 2.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DEMGKBKK_00187 2.7e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DEMGKBKK_00188 1.3e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DEMGKBKK_00189 1.3e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DEMGKBKK_00190 2.4e-30 yocH M Lysin motif
DEMGKBKK_00191 1.3e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DEMGKBKK_00192 1.6e-145 rpsA 1.17.7.4 J Ribosomal protein S1
DEMGKBKK_00193 1.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DEMGKBKK_00194 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DEMGKBKK_00195 6.6e-229 S Tetratricopeptide repeat protein
DEMGKBKK_00196 5.7e-158 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DEMGKBKK_00197 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DEMGKBKK_00198 4.4e-113 hlyIII S protein, hemolysin III
DEMGKBKK_00199 9.4e-147 DegV S Uncharacterised protein, DegV family COG1307
DEMGKBKK_00200 3.5e-35 yozE S Belongs to the UPF0346 family
DEMGKBKK_00201 1.4e-276 yjcE P Sodium proton antiporter
DEMGKBKK_00202 3.8e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DEMGKBKK_00203 7e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEMGKBKK_00204 3.4e-152 dprA LU DNA protecting protein DprA
DEMGKBKK_00205 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DEMGKBKK_00206 3.6e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
DEMGKBKK_00207 1.1e-167 xerC D Phage integrase, N-terminal SAM-like domain
DEMGKBKK_00208 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DEMGKBKK_00209 9.4e-232 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DEMGKBKK_00210 1.2e-174 lacX 5.1.3.3 G Aldose 1-epimerase
DEMGKBKK_00211 9.1e-23
DEMGKBKK_00212 7.9e-21 L PFAM IS66 Orf2 family protein
DEMGKBKK_00213 3.7e-26 S Transposase C of IS166 homeodomain
DEMGKBKK_00214 2.8e-134 L Transposase and inactivated derivatives
DEMGKBKK_00216 2.4e-56 L Putative transposase DNA-binding domain
DEMGKBKK_00217 5.5e-53 L Putative transposase DNA-binding domain
DEMGKBKK_00218 1.8e-98 EGP Major facilitator Superfamily
DEMGKBKK_00219 1.4e-50 Q AMP-binding enzyme
DEMGKBKK_00220 0.0 Q AMP-binding enzyme
DEMGKBKK_00223 8.8e-154 2.5.1.140 E Belongs to the cysteine synthase cystathionine beta- synthase family
DEMGKBKK_00224 5e-147 K Helix-turn-helix XRE-family like proteins
DEMGKBKK_00225 5.8e-73 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
DEMGKBKK_00226 1.8e-58 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DEMGKBKK_00227 1.4e-150 xerD L Phage integrase, N-terminal SAM-like domain
DEMGKBKK_00228 1.9e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEMGKBKK_00229 2.9e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DEMGKBKK_00230 1.9e-48 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
DEMGKBKK_00231 2e-277 E Amino acid permease
DEMGKBKK_00232 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
DEMGKBKK_00233 1.9e-247 ynbB 4.4.1.1 P aluminum resistance
DEMGKBKK_00234 5.4e-44 ktrA P domain protein
DEMGKBKK_00235 4.8e-55 ktrA P domain protein
DEMGKBKK_00236 3.1e-60 ktrB P Potassium uptake protein
DEMGKBKK_00237 7.6e-102 ktrB P Potassium uptake protein
DEMGKBKK_00238 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DEMGKBKK_00239 1.7e-78 C Flavodoxin
DEMGKBKK_00240 8.9e-113 3.6.1.27 I Acid phosphatase homologues
DEMGKBKK_00241 1.3e-105 lacA 2.3.1.79 S Transferase hexapeptide repeat
DEMGKBKK_00242 4.1e-206 pbpX1 V Beta-lactamase
DEMGKBKK_00243 7e-150 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DEMGKBKK_00244 2.2e-91 S ECF-type riboflavin transporter, S component
DEMGKBKK_00245 1.2e-230 S Putative peptidoglycan binding domain
DEMGKBKK_00246 4.3e-107 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
DEMGKBKK_00247 3.2e-31 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
DEMGKBKK_00248 1.2e-17
DEMGKBKK_00249 1.8e-72
DEMGKBKK_00250 1.8e-43 M Glycosyl transferase
DEMGKBKK_00251 1.3e-171 ydaM M Glycosyl transferase family group 2
DEMGKBKK_00252 1.1e-153 G Glycosyl hydrolases family 8
DEMGKBKK_00254 5.9e-120 yfbR S HD containing hydrolase-like enzyme
DEMGKBKK_00255 1.8e-156 L HNH nucleases
DEMGKBKK_00256 6.8e-136 glnQ E ABC transporter, ATP-binding protein
DEMGKBKK_00257 8.7e-290 glnP P ABC transporter permease
DEMGKBKK_00258 2.8e-122 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
DEMGKBKK_00259 2.4e-62 yeaO S Protein of unknown function, DUF488
DEMGKBKK_00260 2.5e-120 terC P Integral membrane protein TerC family
DEMGKBKK_00261 3.9e-90 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
DEMGKBKK_00262 9.8e-129 cobB K SIR2 family
DEMGKBKK_00263 5.9e-85
DEMGKBKK_00264 2.7e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEMGKBKK_00265 1.4e-175 S Alpha/beta hydrolase of unknown function (DUF915)
DEMGKBKK_00266 1.1e-144 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DEMGKBKK_00267 1.2e-134 ypuA S Protein of unknown function (DUF1002)
DEMGKBKK_00268 1.2e-157 epsV 2.7.8.12 S glycosyl transferase family 2
DEMGKBKK_00269 2.5e-126 S Alpha/beta hydrolase family
DEMGKBKK_00270 2.8e-114 GM NmrA-like family
DEMGKBKK_00271 1.8e-53
DEMGKBKK_00272 2.9e-179 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEMGKBKK_00273 3.9e-122 luxT K Bacterial regulatory proteins, tetR family
DEMGKBKK_00274 1.5e-128
DEMGKBKK_00275 6e-261 glnPH2 P ABC transporter permease
DEMGKBKK_00276 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DEMGKBKK_00277 6e-230 S Cysteine-rich secretory protein family
DEMGKBKK_00278 9e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DEMGKBKK_00279 2.7e-92
DEMGKBKK_00280 4.5e-200 yibE S overlaps another CDS with the same product name
DEMGKBKK_00281 6.4e-129 yibF S overlaps another CDS with the same product name
DEMGKBKK_00282 8.4e-156 I alpha/beta hydrolase fold
DEMGKBKK_00283 3.4e-25
DEMGKBKK_00284 1.3e-105 L Resolvase, N terminal domain
DEMGKBKK_00285 1.5e-255 L Probable transposase
DEMGKBKK_00286 0.0 G Belongs to the glycosyl hydrolase 31 family
DEMGKBKK_00287 5.7e-80 ntd 2.4.2.6 F Nucleoside
DEMGKBKK_00288 5e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
DEMGKBKK_00289 7e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
DEMGKBKK_00290 8.5e-87 uspA T universal stress protein
DEMGKBKK_00291 1.6e-150 phnD P Phosphonate ABC transporter
DEMGKBKK_00292 3.7e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
DEMGKBKK_00293 6.1e-127 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
DEMGKBKK_00294 4.6e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
DEMGKBKK_00295 4.3e-106 tag 3.2.2.20 L glycosylase
DEMGKBKK_00296 3.6e-82
DEMGKBKK_00297 1.4e-272 S Calcineurin-like phosphoesterase
DEMGKBKK_00298 0.0 asnB 6.3.5.4 E Asparagine synthase
DEMGKBKK_00299 4.7e-254 yxbA 6.3.1.12 S ATP-grasp enzyme
DEMGKBKK_00302 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DEMGKBKK_00303 9.6e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DEMGKBKK_00304 4.5e-100 S Iron-sulfur cluster assembly protein
DEMGKBKK_00305 2.4e-228 XK27_04775 S PAS domain
DEMGKBKK_00306 4.3e-225 yttB EGP Major facilitator Superfamily
DEMGKBKK_00307 0.0 pepO 3.4.24.71 O Peptidase family M13
DEMGKBKK_00308 3.5e-113 pbpX2 V Beta-lactamase
DEMGKBKK_00309 6.7e-104 3.2.2.20 K acetyltransferase
DEMGKBKK_00310 5.3e-95
DEMGKBKK_00311 3.7e-32
DEMGKBKK_00312 1.7e-267 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
DEMGKBKK_00313 3.2e-133 glvR K Helix-turn-helix domain, rpiR family
DEMGKBKK_00314 1.6e-185 ansA 3.5.1.1 EJ L-asparaginase, type I
DEMGKBKK_00315 5.4e-15
DEMGKBKK_00316 4.8e-125
DEMGKBKK_00317 3e-237 S response to antibiotic
DEMGKBKK_00318 1.1e-126 pgm3 G Phosphoglycerate mutase family
DEMGKBKK_00319 1.1e-119 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
DEMGKBKK_00320 0.0 helD 3.6.4.12 L DNA helicase
DEMGKBKK_00321 1.1e-107 glnP P ABC transporter permease
DEMGKBKK_00322 1.5e-109 glnQ 3.6.3.21 E ABC transporter
DEMGKBKK_00323 3.4e-149 aatB ET ABC transporter substrate-binding protein
DEMGKBKK_00324 3.2e-77 yjcF S Acetyltransferase (GNAT) domain
DEMGKBKK_00325 1.6e-102 E GDSL-like Lipase/Acylhydrolase
DEMGKBKK_00326 3.9e-170 coaA 2.7.1.33 F Pantothenic acid kinase
DEMGKBKK_00327 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEMGKBKK_00328 4.1e-67 yybA 2.3.1.57 K Transcriptional regulator
DEMGKBKK_00329 8.4e-85 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
DEMGKBKK_00330 2.3e-65 S Peptidase propeptide and YPEB domain
DEMGKBKK_00331 1.3e-95 F Nucleoside 2-deoxyribosyltransferase
DEMGKBKK_00332 9.5e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DEMGKBKK_00333 7.9e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
DEMGKBKK_00334 6.7e-274 V ABC transporter transmembrane region
DEMGKBKK_00335 1.2e-108 S PAS domain
DEMGKBKK_00336 1.1e-10
DEMGKBKK_00337 4.9e-139 pnuC H nicotinamide mononucleotide transporter
DEMGKBKK_00338 2.7e-17 S Protein of unknown function (DUF3290)
DEMGKBKK_00339 6.8e-41 S Protein of unknown function (DUF3290)
DEMGKBKK_00340 1.6e-106 yviA S Protein of unknown function (DUF421)
DEMGKBKK_00341 6.9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEMGKBKK_00342 8.3e-163 dnaQ 2.7.7.7 L EXOIII
DEMGKBKK_00343 4.1e-153 endA F DNA RNA non-specific endonuclease
DEMGKBKK_00344 5.5e-280 pipD E Dipeptidase
DEMGKBKK_00345 1e-196 malK P ATPases associated with a variety of cellular activities
DEMGKBKK_00346 1.9e-158 gtsB P ABC-type sugar transport systems, permease components
DEMGKBKK_00347 2.3e-145 gtsC P Binding-protein-dependent transport system inner membrane component
DEMGKBKK_00348 1.1e-253 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
DEMGKBKK_00349 1.4e-234 G Bacterial extracellular solute-binding protein
DEMGKBKK_00350 6.5e-157 corA P CorA-like Mg2+ transporter protein
DEMGKBKK_00351 1.4e-154 3.5.2.6 V Beta-lactamase enzyme family
DEMGKBKK_00352 6.2e-97 yobS K Bacterial regulatory proteins, tetR family
DEMGKBKK_00353 0.0 ydgH S MMPL family
DEMGKBKK_00354 2.4e-152
DEMGKBKK_00355 1.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
DEMGKBKK_00356 4.3e-124 hipB K Helix-turn-helix
DEMGKBKK_00357 7.2e-152 I alpha/beta hydrolase fold
DEMGKBKK_00358 1.3e-108 yjbF S SNARE associated Golgi protein
DEMGKBKK_00359 9.2e-98 J Acetyltransferase (GNAT) domain
DEMGKBKK_00360 5.3e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DEMGKBKK_00361 3.6e-108 S Terminase-like family
DEMGKBKK_00362 1e-137 S Protein of unknown function (DUF1073)
DEMGKBKK_00363 8.8e-49 S Phage Mu protein F like protein
DEMGKBKK_00364 2.1e-10 S Lysin motif
DEMGKBKK_00365 5.7e-52 S Uncharacterized protein conserved in bacteria (DUF2213)
DEMGKBKK_00366 5.7e-34
DEMGKBKK_00367 5e-91 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
DEMGKBKK_00368 1.4e-20 S Protein of unknown function (DUF4054)
DEMGKBKK_00369 9e-31
DEMGKBKK_00370 1.5e-28
DEMGKBKK_00371 1.7e-35
DEMGKBKK_00372 6.9e-104 Z012_02110 S Protein of unknown function (DUF3383)
DEMGKBKK_00373 1.4e-29
DEMGKBKK_00374 5.3e-11
DEMGKBKK_00376 9e-206 3.4.14.13 M Phage tail tape measure protein TP901
DEMGKBKK_00377 8.7e-54 M LysM domain
DEMGKBKK_00378 2.3e-37
DEMGKBKK_00379 2.8e-111
DEMGKBKK_00380 1.5e-44
DEMGKBKK_00381 2.1e-32
DEMGKBKK_00382 1.2e-123 Z012_12235 S Baseplate J-like protein
DEMGKBKK_00383 2.9e-10
DEMGKBKK_00384 3.8e-36
DEMGKBKK_00385 3.7e-137
DEMGKBKK_00390 1.3e-57
DEMGKBKK_00391 4.6e-20 S Phage uncharacterised protein (Phage_XkdX)
DEMGKBKK_00392 6e-17
DEMGKBKK_00393 4.6e-16
DEMGKBKK_00394 3.6e-22
DEMGKBKK_00395 1.5e-155 M Glycosyl hydrolases family 25
DEMGKBKK_00398 1.7e-59 L Belongs to the 'phage' integrase family
DEMGKBKK_00404 1.2e-10 E Zn peptidase
DEMGKBKK_00405 2.2e-25 K Cro/C1-type HTH DNA-binding domain
DEMGKBKK_00407 2.2e-81 ps308 K AntA/AntB antirepressor
DEMGKBKK_00412 2.7e-17
DEMGKBKK_00415 2.1e-36 S Protein of unknown function (DUF1351)
DEMGKBKK_00416 4.7e-47 S ERF superfamily
DEMGKBKK_00417 1.8e-62 L DnaD domain protein
DEMGKBKK_00434 2e-41 S VRR_NUC
DEMGKBKK_00435 2.9e-07
DEMGKBKK_00439 2.7e-20 ps333 L Terminase small subunit
DEMGKBKK_00440 1.2e-132 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
DEMGKBKK_00441 1.8e-201 csaB M Glycosyl transferases group 1
DEMGKBKK_00442 2.8e-282 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DEMGKBKK_00443 1.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DEMGKBKK_00444 6.6e-221 L Probable transposase
DEMGKBKK_00445 3.9e-62 pacL 3.6.3.8 P P-type ATPase
DEMGKBKK_00446 7e-295 pacL 3.6.3.8 P P-type ATPase
DEMGKBKK_00447 2e-21 pacL 3.6.3.8 P P-type ATPase
DEMGKBKK_00448 1.4e-44 pacL 3.6.3.8 P P-type ATPase
DEMGKBKK_00449 2.1e-224 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
DEMGKBKK_00450 7.1e-259 epsU S Polysaccharide biosynthesis protein
DEMGKBKK_00451 2.2e-133 M Glycosyltransferase sugar-binding region containing DXD motif
DEMGKBKK_00452 5.3e-86 ydcK S Belongs to the SprT family
DEMGKBKK_00454 2.9e-103 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
DEMGKBKK_00455 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DEMGKBKK_00456 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DEMGKBKK_00457 1.1e-206 camS S sex pheromone
DEMGKBKK_00458 2.9e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEMGKBKK_00459 4.2e-259 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DEMGKBKK_00460 6.4e-276 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DEMGKBKK_00461 3e-170 yegS 2.7.1.107 G Lipid kinase
DEMGKBKK_00462 9.7e-113 S Protein of unknown function (DUF1211)
DEMGKBKK_00463 1.4e-119 ybhL S Belongs to the BI1 family
DEMGKBKK_00464 5.6e-53
DEMGKBKK_00465 4.6e-247 nhaC C Na H antiporter NhaC
DEMGKBKK_00466 1.1e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEMGKBKK_00467 2.6e-27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DEMGKBKK_00468 2.1e-123 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
DEMGKBKK_00469 7.3e-109 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
DEMGKBKK_00470 1e-27 cspA K Cold shock protein
DEMGKBKK_00472 4.6e-96 MA20_25245 K Acetyltransferase (GNAT) domain
DEMGKBKK_00477 3.1e-241 emrY EGP Major facilitator Superfamily
DEMGKBKK_00478 6.3e-18 yxdD K Bacterial regulatory proteins, tetR family
DEMGKBKK_00479 1.8e-209 4.2.1.53 S Myosin-crossreactive antigen
DEMGKBKK_00480 6.1e-70 4.2.1.53 S MCRA family
DEMGKBKK_00481 1e-75 2.3.1.128 K Acetyltransferase (GNAT) domain
DEMGKBKK_00482 2e-89
DEMGKBKK_00483 6.9e-23 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
DEMGKBKK_00484 3.9e-101 pncA Q Isochorismatase family
DEMGKBKK_00485 1.2e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
DEMGKBKK_00487 6.5e-53
DEMGKBKK_00488 2.2e-237 I Protein of unknown function (DUF2974)
DEMGKBKK_00489 3.7e-120 yhiD S MgtC family
DEMGKBKK_00491 1.6e-30
DEMGKBKK_00494 1.5e-29 WQ51_00220 K Helix-turn-helix XRE-family like proteins
DEMGKBKK_00495 6.6e-73 ybbL S ABC transporter, ATP-binding protein
DEMGKBKK_00496 4.3e-130 ybbM S Uncharacterised protein family (UPF0014)
DEMGKBKK_00497 4.2e-53 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DEMGKBKK_00498 4.6e-231 S LPXTG cell wall anchor motif
DEMGKBKK_00499 2.3e-147 S Putative ABC-transporter type IV
DEMGKBKK_00500 2.5e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
DEMGKBKK_00501 6.5e-85 S ECF transporter, substrate-specific component
DEMGKBKK_00502 3e-58 S Domain of unknown function (DUF4430)
DEMGKBKK_00503 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
DEMGKBKK_00504 1.2e-175 K AI-2E family transporter
DEMGKBKK_00505 4.4e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
DEMGKBKK_00506 1.3e-11
DEMGKBKK_00507 6.4e-44
DEMGKBKK_00508 4.8e-129 XK27_08845 S ABC transporter, ATP-binding protein
DEMGKBKK_00509 6.9e-119 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
DEMGKBKK_00510 1.3e-171 ABC-SBP S ABC transporter
DEMGKBKK_00511 1.7e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DEMGKBKK_00512 9.7e-163 yvgN C Aldo keto reductase
DEMGKBKK_00514 0.0 tetP J elongation factor G
DEMGKBKK_00515 1.6e-143 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
DEMGKBKK_00516 4e-28
DEMGKBKK_00517 1.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DEMGKBKK_00518 1.2e-168 yniA G Phosphotransferase enzyme family
DEMGKBKK_00519 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
DEMGKBKK_00520 1.1e-262 E amino acid
DEMGKBKK_00521 0.0 L Helicase C-terminal domain protein
DEMGKBKK_00522 1.6e-193 pbpX1 V Beta-lactamase
DEMGKBKK_00523 6.7e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DEMGKBKK_00524 2.8e-199 S C4-dicarboxylate anaerobic carrier
DEMGKBKK_00525 2.9e-35
DEMGKBKK_00526 6.7e-11 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
DEMGKBKK_00527 3.4e-241 N Uncharacterized conserved protein (DUF2075)
DEMGKBKK_00528 3.3e-59 pdxH S Pyridoxamine 5'-phosphate oxidase
DEMGKBKK_00529 1.9e-09 pepO 3.4.24.71 O Peptidase family M13
DEMGKBKK_00530 0.0 pepO 3.4.24.71 O Peptidase family M13
DEMGKBKK_00531 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
DEMGKBKK_00532 1.4e-101 L PFAM transposase, IS4 family protein
DEMGKBKK_00533 7.9e-24 L PFAM transposase, IS4 family protein
DEMGKBKK_00534 0.0
DEMGKBKK_00535 0.0 S PglZ domain
DEMGKBKK_00536 2.5e-208 2.1.1.72 V Eco57I restriction-modification methylase
DEMGKBKK_00537 4.8e-107 V Eco57I restriction-modification methylase
DEMGKBKK_00538 6.6e-216 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
DEMGKBKK_00539 2.3e-110 S Domain of unknown function (DUF1788)
DEMGKBKK_00540 2.2e-105 S Putative inner membrane protein (DUF1819)
DEMGKBKK_00541 1.8e-236 S Protein of unknown function DUF262
DEMGKBKK_00542 2.1e-151
DEMGKBKK_00543 9.9e-74 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
DEMGKBKK_00544 6e-44 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
DEMGKBKK_00545 8e-31
DEMGKBKK_00546 3.4e-115 metQ2 P Belongs to the nlpA lipoprotein family
DEMGKBKK_00547 3e-19
DEMGKBKK_00548 1.6e-42 4.4.1.5 E lactoylglutathione lyase activity
DEMGKBKK_00549 1.8e-65 S ASCH domain
DEMGKBKK_00550 2.4e-109 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DEMGKBKK_00551 4.7e-81
DEMGKBKK_00552 2e-302
DEMGKBKK_00553 1.8e-46 L COG2963 Transposase and inactivated derivatives
DEMGKBKK_00554 1.1e-30 L COG2963 Transposase and inactivated derivatives
DEMGKBKK_00555 5.6e-71 S Iron-sulphur cluster biosynthesis
DEMGKBKK_00557 4.6e-126 3.6.1.13, 3.6.1.55 F NUDIX domain
DEMGKBKK_00558 2.9e-268 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DEMGKBKK_00559 6e-105 pncA Q Isochorismatase family
DEMGKBKK_00560 1.4e-49 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
DEMGKBKK_00561 1.3e-235 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DEMGKBKK_00562 4.2e-55 doc S Fic/DOC family
DEMGKBKK_00566 2.2e-159 cjaA ET ABC transporter substrate-binding protein
DEMGKBKK_00567 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DEMGKBKK_00568 3.1e-87 P ABC transporter permease
DEMGKBKK_00569 3.9e-111 papP P ABC transporter, permease protein
DEMGKBKK_00570 1.3e-69 adhR K helix_turn_helix, mercury resistance
DEMGKBKK_00571 2.8e-27 S Uncharacterized protein conserved in bacteria (DUF2255)
DEMGKBKK_00572 2.2e-108 G Antibiotic biosynthesis monooxygenase
DEMGKBKK_00573 4.8e-76 lacA 2.3.1.79 S Maltose acetyltransferase
DEMGKBKK_00574 2.2e-67 4.1.1.45 S Amidohydrolase
DEMGKBKK_00575 2.9e-72 4.1.1.45 S Amidohydrolase
DEMGKBKK_00577 9.4e-65 S Abi-like protein
DEMGKBKK_00578 4.5e-84 kptA H Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
DEMGKBKK_00579 1.2e-70 fabK 1.3.1.9 S Nitronate monooxygenase
DEMGKBKK_00580 2.4e-31
DEMGKBKK_00581 8.8e-229 yrvN L AAA C-terminal domain
DEMGKBKK_00582 8.9e-140 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
DEMGKBKK_00583 1.4e-87 K Acetyltransferase (GNAT) family
DEMGKBKK_00584 1.9e-33 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
DEMGKBKK_00585 3.2e-59 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
DEMGKBKK_00586 9.8e-72 dps P Belongs to the Dps family
DEMGKBKK_00587 3.9e-34 copZ C Heavy-metal-associated domain
DEMGKBKK_00588 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
DEMGKBKK_00589 7.6e-223 mepA V MATE efflux family protein
DEMGKBKK_00590 1.9e-59 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
DEMGKBKK_00593 0.0 uvrA3 L excinuclease ABC, A subunit
DEMGKBKK_00594 9.8e-94 yyaR K Acetyltransferase (GNAT) domain
DEMGKBKK_00595 6.5e-16 mta K helix_turn_helix, mercury resistance
DEMGKBKK_00596 2e-61 mta K helix_turn_helix, mercury resistance
DEMGKBKK_00597 3.5e-12 mta K helix_turn_helix, mercury resistance
DEMGKBKK_00598 3.1e-20 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
DEMGKBKK_00599 2.9e-69 S Iron-sulphur cluster biosynthesis
DEMGKBKK_00600 8.3e-191 ybiR P Citrate transporter
DEMGKBKK_00601 2.3e-96 lemA S LemA family
DEMGKBKK_00602 5.6e-161 htpX O Belongs to the peptidase M48B family
DEMGKBKK_00603 4.3e-172 K helix_turn_helix, arabinose operon control protein
DEMGKBKK_00604 5.5e-245 cbiO1 S ABC transporter, ATP-binding protein
DEMGKBKK_00605 3.7e-90 P Cobalt transport protein
DEMGKBKK_00606 1.5e-171 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
DEMGKBKK_00607 4.2e-78 S SLAP domain
DEMGKBKK_00608 4.6e-100 S Bacteriocin helveticin-J
DEMGKBKK_00609 1.3e-106 K Helix-turn-helix XRE-family like proteins
DEMGKBKK_00610 4.3e-91 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DEMGKBKK_00611 6.3e-179 htrA 3.4.21.107 O serine protease
DEMGKBKK_00612 6.3e-148 vicX 3.1.26.11 S domain protein
DEMGKBKK_00613 2.2e-148 yycI S YycH protein
DEMGKBKK_00614 9.7e-242 yycH S YycH protein
DEMGKBKK_00615 2e-306 vicK 2.7.13.3 T Histidine kinase
DEMGKBKK_00616 2.8e-131 K response regulator
DEMGKBKK_00618 1.1e-33
DEMGKBKK_00620 1.9e-119
DEMGKBKK_00621 1.2e-29 L transposase, IS605 OrfB family
DEMGKBKK_00622 5.3e-128 arbV 2.3.1.51 I Acyl-transferase
DEMGKBKK_00623 1.9e-142 arbx M Glycosyl transferase family 8
DEMGKBKK_00624 1.1e-183 arbY M Glycosyl transferase family 8
DEMGKBKK_00625 2.9e-160 arbY M Glycosyl transferase family 8
DEMGKBKK_00626 2.5e-166 arbZ I Phosphate acyltransferases
DEMGKBKK_00627 2.5e-107 K Transcriptional regulator, LysR family
DEMGKBKK_00628 3.5e-60 K LysR substrate binding domain
DEMGKBKK_00629 7.7e-41 K LysR substrate binding domain
DEMGKBKK_00631 8.4e-79 S Threonine/Serine exporter, ThrE
DEMGKBKK_00632 4.4e-138 thrE S Putative threonine/serine exporter
DEMGKBKK_00633 1.9e-289 S ABC transporter
DEMGKBKK_00634 1e-55
DEMGKBKK_00635 1.4e-98 rimL J Acetyltransferase (GNAT) domain
DEMGKBKK_00636 2e-89 S Protein of unknown function (DUF554)
DEMGKBKK_00637 1.9e-13 S Protein of unknown function (DUF554)
DEMGKBKK_00638 8.1e-211 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DEMGKBKK_00639 0.0 pepF E oligoendopeptidase F
DEMGKBKK_00640 4.8e-51 Z012_06740 S Fic/DOC family
DEMGKBKK_00641 1e-41 S Enterocin A Immunity
DEMGKBKK_00642 8.9e-33 lctP C L-lactate permease
DEMGKBKK_00643 5.9e-51 lctP C L-lactate permease
DEMGKBKK_00644 2.3e-51 lctP C L-lactate permease
DEMGKBKK_00645 4.2e-102 potB E Binding-protein-dependent transport system inner membrane component
DEMGKBKK_00646 3e-105 potC3 E Binding-protein-dependent transport system inner membrane component
DEMGKBKK_00647 3.3e-133 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DEMGKBKK_00648 2.6e-141 potD2 P ABC transporter
DEMGKBKK_00649 3e-248 ade 3.5.4.2 F Adenine deaminase C-terminal domain
DEMGKBKK_00651 2.3e-71 gepA K Protein of unknown function (DUF4065)
DEMGKBKK_00652 1.1e-15 ps301 K Protein of unknown function (DUF4065)
DEMGKBKK_00653 0.0 yjbQ P TrkA C-terminal domain protein
DEMGKBKK_00654 7.6e-205 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
DEMGKBKK_00655 4.5e-198 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DEMGKBKK_00656 2.2e-169 S SLAP domain
DEMGKBKK_00657 2e-37 S Protein of unknown function (DUF2922)
DEMGKBKK_00658 7e-17
DEMGKBKK_00661 3.7e-85
DEMGKBKK_00662 1.4e-128 kup P Transport of potassium into the cell
DEMGKBKK_00663 2.6e-233 kup P Transport of potassium into the cell
DEMGKBKK_00664 4.5e-149 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
DEMGKBKK_00665 3.7e-114 dedA S SNARE-like domain protein
DEMGKBKK_00666 2.1e-79 S Protein of unknown function (DUF1461)
DEMGKBKK_00667 2.9e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DEMGKBKK_00668 2.7e-85 yutD S Protein of unknown function (DUF1027)
DEMGKBKK_00669 1.2e-276 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
DEMGKBKK_00670 1.1e-55
DEMGKBKK_00671 2.4e-264 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DEMGKBKK_00672 6e-180 ccpA K catabolite control protein A
DEMGKBKK_00673 6.3e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DEMGKBKK_00674 1e-44
DEMGKBKK_00675 2.1e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DEMGKBKK_00676 2.7e-149 ykuT M mechanosensitive ion channel
DEMGKBKK_00677 2.7e-114 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DEMGKBKK_00678 2e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DEMGKBKK_00679 2.5e-68 yslB S Protein of unknown function (DUF2507)
DEMGKBKK_00680 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DEMGKBKK_00681 4.6e-54 trxA O Belongs to the thioredoxin family
DEMGKBKK_00682 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DEMGKBKK_00683 2.4e-50 yrzB S Belongs to the UPF0473 family
DEMGKBKK_00684 1e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DEMGKBKK_00685 2e-42 yrzL S Belongs to the UPF0297 family
DEMGKBKK_00686 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DEMGKBKK_00687 1.4e-86
DEMGKBKK_00688 4.1e-70
DEMGKBKK_00689 5.2e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DEMGKBKK_00690 1.2e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
DEMGKBKK_00691 5.6e-211 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DEMGKBKK_00692 1.4e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DEMGKBKK_00693 2.2e-35 yajC U Preprotein translocase
DEMGKBKK_00694 2.8e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DEMGKBKK_00695 3.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DEMGKBKK_00696 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DEMGKBKK_00697 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DEMGKBKK_00698 3.3e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DEMGKBKK_00699 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DEMGKBKK_00700 1.3e-88
DEMGKBKK_00701 1.6e-45
DEMGKBKK_00702 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
DEMGKBKK_00703 2e-229 scrB 3.2.1.26 GH32 G invertase
DEMGKBKK_00704 9.1e-181 scrR K Transcriptional regulator, LacI family
DEMGKBKK_00705 6.5e-123 liaI S membrane
DEMGKBKK_00706 2.4e-75 XK27_02470 K LytTr DNA-binding domain
DEMGKBKK_00707 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DEMGKBKK_00708 0.0 uup S ABC transporter, ATP-binding protein
DEMGKBKK_00710 2.2e-66 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
DEMGKBKK_00711 1.1e-83 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DEMGKBKK_00712 7.9e-199 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DEMGKBKK_00713 1.4e-28 S Toxin ToxN, type III toxin-antitoxin system
DEMGKBKK_00714 3.2e-127 K UTRA
DEMGKBKK_00715 5.2e-181 S Oxidoreductase family, NAD-binding Rossmann fold
DEMGKBKK_00716 8.7e-125 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DEMGKBKK_00717 5.3e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DEMGKBKK_00718 1.4e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
DEMGKBKK_00719 3.4e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
DEMGKBKK_00720 9.9e-86 S ECF transporter, substrate-specific component
DEMGKBKK_00721 1.3e-126 fat 3.1.2.21 I Acyl-ACP thioesterase
DEMGKBKK_00722 2.2e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DEMGKBKK_00723 2.7e-58 yabA L Involved in initiation control of chromosome replication
DEMGKBKK_00724 2.4e-153 holB 2.7.7.7 L DNA polymerase III
DEMGKBKK_00725 1.4e-50 yaaQ S Cyclic-di-AMP receptor
DEMGKBKK_00726 3.3e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DEMGKBKK_00727 4.5e-33 S Protein of unknown function (DUF2508)
DEMGKBKK_00728 2.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DEMGKBKK_00729 1.4e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DEMGKBKK_00730 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEMGKBKK_00731 5e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DEMGKBKK_00732 7.5e-112 rsmC 2.1.1.172 J Methyltransferase
DEMGKBKK_00733 1e-44 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
DEMGKBKK_00734 5e-29 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
DEMGKBKK_00735 5.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DEMGKBKK_00736 1e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DEMGKBKK_00737 3.3e-119 yfdV S Membrane transport protein
DEMGKBKK_00738 1.1e-22 yfdV S Membrane transport protein
DEMGKBKK_00739 3.6e-26 yfdV S Membrane transport protein
DEMGKBKK_00740 2.9e-117 phoU P Plays a role in the regulation of phosphate uptake
DEMGKBKK_00741 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEMGKBKK_00742 1.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DEMGKBKK_00743 9.1e-156 pstA P Phosphate transport system permease protein PstA
DEMGKBKK_00744 7e-173 pstC P probably responsible for the translocation of the substrate across the membrane
DEMGKBKK_00745 9.5e-158 pstS P Phosphate
DEMGKBKK_00746 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DEMGKBKK_00747 3.4e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DEMGKBKK_00748 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
DEMGKBKK_00749 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DEMGKBKK_00750 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DEMGKBKK_00751 4.9e-279 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
DEMGKBKK_00752 8.3e-34
DEMGKBKK_00753 1.4e-93 sigH K Belongs to the sigma-70 factor family
DEMGKBKK_00754 7.8e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEMGKBKK_00755 7.9e-76 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DEMGKBKK_00756 5.6e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DEMGKBKK_00757 3.4e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DEMGKBKK_00758 1.7e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DEMGKBKK_00759 2.8e-102 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
DEMGKBKK_00760 4.9e-53
DEMGKBKK_00761 1.3e-265 pepC 3.4.22.40 E Peptidase C1-like family
DEMGKBKK_00762 3.5e-46
DEMGKBKK_00763 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
DEMGKBKK_00764 2.1e-182 S AAA domain
DEMGKBKK_00765 2.2e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DEMGKBKK_00766 5.5e-23
DEMGKBKK_00767 2.5e-161 czcD P cation diffusion facilitator family transporter
DEMGKBKK_00768 2e-126 pgm3 G Belongs to the phosphoglycerate mutase family
DEMGKBKK_00769 6.4e-134 S membrane transporter protein
DEMGKBKK_00770 3.9e-111 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DEMGKBKK_00771 2.3e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
DEMGKBKK_00772 9.3e-62 S Protein of unknown function (DUF805)
DEMGKBKK_00773 1.6e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
DEMGKBKK_00774 1.7e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DEMGKBKK_00775 4.6e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DEMGKBKK_00776 1.8e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEMGKBKK_00777 1.5e-149 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEMGKBKK_00778 1.7e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DEMGKBKK_00779 1.1e-60 rplQ J Ribosomal protein L17
DEMGKBKK_00780 1.8e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEMGKBKK_00781 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DEMGKBKK_00782 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DEMGKBKK_00783 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DEMGKBKK_00784 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DEMGKBKK_00785 6e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DEMGKBKK_00786 6.9e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DEMGKBKK_00787 4.5e-71 rplO J Binds to the 23S rRNA
DEMGKBKK_00788 2.3e-24 rpmD J Ribosomal protein L30
DEMGKBKK_00789 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DEMGKBKK_00790 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DEMGKBKK_00791 9.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DEMGKBKK_00792 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DEMGKBKK_00793 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEMGKBKK_00794 1.8e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DEMGKBKK_00795 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DEMGKBKK_00796 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DEMGKBKK_00797 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DEMGKBKK_00798 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
DEMGKBKK_00799 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DEMGKBKK_00800 1.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DEMGKBKK_00801 2.6e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DEMGKBKK_00802 3.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DEMGKBKK_00803 1.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DEMGKBKK_00804 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DEMGKBKK_00805 8.7e-105 rplD J Forms part of the polypeptide exit tunnel
DEMGKBKK_00806 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DEMGKBKK_00807 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
DEMGKBKK_00808 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DEMGKBKK_00809 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DEMGKBKK_00810 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DEMGKBKK_00811 2.1e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DEMGKBKK_00812 1.1e-30 L COG2963 Transposase and inactivated derivatives
DEMGKBKK_00813 9.6e-64 L COG2963 Transposase and inactivated derivatives
DEMGKBKK_00814 1e-80 L COG2963 Transposase and inactivated derivatives
DEMGKBKK_00815 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEMGKBKK_00816 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DEMGKBKK_00817 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DEMGKBKK_00818 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
DEMGKBKK_00820 1.6e-08
DEMGKBKK_00821 4.6e-77
DEMGKBKK_00823 6.4e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DEMGKBKK_00824 2.1e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DEMGKBKK_00825 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DEMGKBKK_00826 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DEMGKBKK_00827 3.5e-238 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DEMGKBKK_00828 3.5e-61 yabR J S1 RNA binding domain
DEMGKBKK_00829 9.8e-59 divIC D Septum formation initiator
DEMGKBKK_00830 1.8e-34 yabO J S4 domain protein
DEMGKBKK_00831 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DEMGKBKK_00832 1.9e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DEMGKBKK_00833 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DEMGKBKK_00834 1.4e-127 S (CBS) domain
DEMGKBKK_00835 4.6e-92 K transcriptional regulator
DEMGKBKK_00836 1.4e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DEMGKBKK_00837 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DEMGKBKK_00838 1.8e-244 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DEMGKBKK_00839 2.5e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DEMGKBKK_00840 1.5e-39 rpmE2 J Ribosomal protein L31
DEMGKBKK_00841 2.7e-154 S Sucrose-6F-phosphate phosphohydrolase
DEMGKBKK_00842 3.4e-278 ybeC E amino acid
DEMGKBKK_00843 6.2e-227 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DEMGKBKK_00844 2.9e-14 1.1.1.1 C nadph quinone reductase
DEMGKBKK_00845 1.3e-202 L transposase, IS605 OrfB family
DEMGKBKK_00847 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DEMGKBKK_00848 1.3e-45 K Helix-turn-helix
DEMGKBKK_00849 1.1e-42 K DNA-binding helix-turn-helix protein
DEMGKBKK_00850 1e-53 K DNA-binding helix-turn-helix protein
DEMGKBKK_00851 2.2e-102 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DEMGKBKK_00852 1.6e-222 pbuX F xanthine permease
DEMGKBKK_00853 1.4e-158 msmR K AraC-like ligand binding domain
DEMGKBKK_00854 5.3e-283 pipD E Dipeptidase
DEMGKBKK_00855 4.3e-40 S Haloacid dehalogenase-like hydrolase
DEMGKBKK_00856 8.1e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DEMGKBKK_00857 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DEMGKBKK_00858 2.6e-52 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DEMGKBKK_00859 4e-66 S Domain of unknown function (DUF1934)
DEMGKBKK_00860 4.8e-265 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
DEMGKBKK_00861 6.4e-21
DEMGKBKK_00862 9.4e-148 GK ROK family
DEMGKBKK_00863 3.9e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DEMGKBKK_00864 3.2e-220 S SLAP domain
DEMGKBKK_00865 2.1e-103 S SLAP domain
DEMGKBKK_00866 1.8e-195 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DEMGKBKK_00867 7.7e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
DEMGKBKK_00868 2.6e-37 veg S Biofilm formation stimulator VEG
DEMGKBKK_00869 9.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DEMGKBKK_00870 6.5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DEMGKBKK_00871 2.3e-147 tatD L hydrolase, TatD family
DEMGKBKK_00872 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DEMGKBKK_00873 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
DEMGKBKK_00874 1.5e-107 S TPM domain
DEMGKBKK_00875 1.6e-90 comEB 3.5.4.12 F MafB19-like deaminase
DEMGKBKK_00876 2.8e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DEMGKBKK_00877 9.9e-114 E Belongs to the SOS response-associated peptidase family
DEMGKBKK_00879 4.9e-114
DEMGKBKK_00880 6.3e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DEMGKBKK_00881 7.6e-68 hsp O Belongs to the small heat shock protein (HSP20) family
DEMGKBKK_00882 1.1e-255 pepC 3.4.22.40 E aminopeptidase
DEMGKBKK_00883 9.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DEMGKBKK_00884 1.8e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
DEMGKBKK_00885 2.9e-251 pepC 3.4.22.40 E aminopeptidase
DEMGKBKK_00887 2.2e-52
DEMGKBKK_00888 1.4e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DEMGKBKK_00889 1.2e-258 S Fibronectin type III domain
DEMGKBKK_00890 0.0 XK27_08315 M Sulfatase
DEMGKBKK_00891 2.8e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DEMGKBKK_00892 3.4e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DEMGKBKK_00893 1.3e-99 G Aldose 1-epimerase
DEMGKBKK_00894 1.9e-109 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DEMGKBKK_00895 8.4e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DEMGKBKK_00896 7.8e-132
DEMGKBKK_00897 1.1e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DEMGKBKK_00898 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DEMGKBKK_00899 2.3e-29 secG U Preprotein translocase
DEMGKBKK_00900 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DEMGKBKK_00901 4.9e-177 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DEMGKBKK_00902 1.3e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
DEMGKBKK_00903 2e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
DEMGKBKK_00931 1.7e-111 L Phage integrase, N-terminal SAM-like domain
DEMGKBKK_00932 3.5e-44 L Single-strand binding protein family
DEMGKBKK_00933 2e-138 L Replication initiation factor
DEMGKBKK_00934 6.5e-94 S Lysin motif
DEMGKBKK_00936 2e-106 S NgoFVII restriction endonuclease
DEMGKBKK_00937 9.1e-159 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
DEMGKBKK_00938 2.6e-55 vsr L DNA mismatch endonuclease Vsr
DEMGKBKK_00940 1.7e-44 repA S Replication initiator protein A
DEMGKBKK_00941 5.3e-25
DEMGKBKK_00942 5.4e-24 S Protein of unknown function (DUF2922)
DEMGKBKK_00944 7.9e-137 M NlpC/P60 family
DEMGKBKK_00945 3e-126 M NlpC P60 family protein
DEMGKBKK_00946 2.2e-91 M NlpC/P60 family
DEMGKBKK_00947 1.2e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
DEMGKBKK_00948 3.7e-24
DEMGKBKK_00949 1.9e-275 S O-antigen ligase like membrane protein
DEMGKBKK_00950 6.3e-95
DEMGKBKK_00951 1e-66
DEMGKBKK_00952 1.7e-131 yvpB S Peptidase_C39 like family
DEMGKBKK_00953 5.4e-55 L transposase, IS605 OrfB family
DEMGKBKK_00959 2.6e-11 L Replication initiation factor
DEMGKBKK_00961 1.5e-78
DEMGKBKK_00962 9.3e-83 S COG NOG38524 non supervised orthologous group
DEMGKBKK_00964 3.1e-09
DEMGKBKK_00965 8.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DEMGKBKK_00966 2.7e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DEMGKBKK_00967 1.2e-174 phoH T phosphate starvation-inducible protein PhoH
DEMGKBKK_00968 2.7e-68 yqeY S YqeY-like protein
DEMGKBKK_00969 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DEMGKBKK_00970 2.2e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
DEMGKBKK_00971 8e-106 S Peptidase family M23
DEMGKBKK_00972 9.3e-161 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
DEMGKBKK_00973 1.4e-105
DEMGKBKK_00974 1.1e-37 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DEMGKBKK_00975 9.7e-82 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DEMGKBKK_00976 1.2e-23 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
DEMGKBKK_00977 4.7e-122 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
DEMGKBKK_00978 1.3e-244 thrC 4.2.3.1 E Threonine synthase
DEMGKBKK_00979 4.8e-115 lysC 2.7.2.4 E Belongs to the aspartokinase family
DEMGKBKK_00980 5.1e-84 lysC 2.7.2.4 E Belongs to the aspartokinase family
DEMGKBKK_00981 1.5e-26 lysC 2.7.2.4 E Belongs to the aspartokinase family
DEMGKBKK_00982 1.1e-102 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
DEMGKBKK_00983 2.9e-28
DEMGKBKK_00984 5.6e-42
DEMGKBKK_00985 3.5e-106 K LysR substrate binding domain
DEMGKBKK_00986 1.2e-18
DEMGKBKK_00987 5.3e-212 S Sterol carrier protein domain
DEMGKBKK_00988 6.4e-96 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
DEMGKBKK_00989 6.7e-125 arcC 2.7.2.2 E Belongs to the carbamate kinase family
DEMGKBKK_00990 1.1e-31 arcC 2.7.2.2 E Belongs to the carbamate kinase family
DEMGKBKK_00991 1.4e-187 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DEMGKBKK_00992 8.4e-166 arcA 3.5.3.6 E Arginine
DEMGKBKK_00993 9.2e-26 arcA 3.5.3.6 E Arginine
DEMGKBKK_00994 1.3e-154 lysR5 K LysR substrate binding domain
DEMGKBKK_00995 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
DEMGKBKK_00996 7.6e-83 3.4.21.96 S SLAP domain
DEMGKBKK_00997 1.6e-248 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DEMGKBKK_00998 1.1e-147 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
DEMGKBKK_00999 2.6e-30 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DEMGKBKK_01000 3e-122 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DEMGKBKK_01001 7e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DEMGKBKK_01002 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
DEMGKBKK_01003 1.9e-116 srtA 3.4.22.70 M sortase family
DEMGKBKK_01004 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DEMGKBKK_01005 2.1e-20
DEMGKBKK_01006 6e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DEMGKBKK_01007 0.0 dnaK O Heat shock 70 kDa protein
DEMGKBKK_01008 1.3e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DEMGKBKK_01009 1.2e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DEMGKBKK_01010 1.4e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DEMGKBKK_01011 2.8e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DEMGKBKK_01012 1.1e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DEMGKBKK_01013 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DEMGKBKK_01014 1.2e-46 rplGA J ribosomal protein
DEMGKBKK_01015 1.2e-46 ylxR K Protein of unknown function (DUF448)
DEMGKBKK_01016 2.9e-194 nusA K Participates in both transcription termination and antitermination
DEMGKBKK_01017 6.7e-81 rimP J Required for maturation of 30S ribosomal subunits
DEMGKBKK_01018 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DEMGKBKK_01019 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DEMGKBKK_01020 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DEMGKBKK_01021 5.1e-145 cdsA 2.7.7.41 I Belongs to the CDS family
DEMGKBKK_01022 1.6e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DEMGKBKK_01023 7.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DEMGKBKK_01024 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DEMGKBKK_01025 8.3e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DEMGKBKK_01026 1.4e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
DEMGKBKK_01027 4.2e-197 yabB 2.1.1.223 L Methyltransferase small domain
DEMGKBKK_01028 5.1e-113 plsC 2.3.1.51 I Acyltransferase
DEMGKBKK_01029 1.5e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DEMGKBKK_01030 0.0 pepO 3.4.24.71 O Peptidase family M13
DEMGKBKK_01031 2.1e-300 mdlB V ABC transporter
DEMGKBKK_01032 1.6e-297 mdlA V ABC transporter
DEMGKBKK_01033 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
DEMGKBKK_01034 7.4e-37 ynzC S UPF0291 protein
DEMGKBKK_01035 2.8e-111 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DEMGKBKK_01036 3.4e-146 E GDSL-like Lipase/Acylhydrolase family
DEMGKBKK_01037 6.4e-99 ung2 3.2.2.27 L Uracil-DNA glycosylase
DEMGKBKK_01038 5.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DEMGKBKK_01039 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DEMGKBKK_01040 1.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DEMGKBKK_01041 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DEMGKBKK_01042 3.8e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DEMGKBKK_01043 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DEMGKBKK_01044 1.5e-256 yfnA E amino acid
DEMGKBKK_01045 4e-43
DEMGKBKK_01046 1.7e-289 pipD E Dipeptidase
DEMGKBKK_01047 1.3e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DEMGKBKK_01048 0.0 smc D Required for chromosome condensation and partitioning
DEMGKBKK_01049 1.3e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DEMGKBKK_01050 0.0 oppA E ABC transporter substrate-binding protein
DEMGKBKK_01051 0.0 oppA E ABC transporter substrate-binding protein
DEMGKBKK_01052 3.3e-148 oppC P Binding-protein-dependent transport system inner membrane component
DEMGKBKK_01053 2.5e-175 oppB P ABC transporter permease
DEMGKBKK_01054 5.3e-181 oppF P Belongs to the ABC transporter superfamily
DEMGKBKK_01055 2e-194 oppD P Belongs to the ABC transporter superfamily
DEMGKBKK_01056 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DEMGKBKK_01057 2.1e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DEMGKBKK_01058 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DEMGKBKK_01059 9.9e-305 yloV S DAK2 domain fusion protein YloV
DEMGKBKK_01060 6.8e-57 asp S Asp23 family, cell envelope-related function
DEMGKBKK_01061 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DEMGKBKK_01062 1.1e-47
DEMGKBKK_01063 6.4e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
DEMGKBKK_01064 2.6e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DEMGKBKK_01065 9.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DEMGKBKK_01066 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
DEMGKBKK_01067 1e-145 stp 3.1.3.16 T phosphatase
DEMGKBKK_01068 5.4e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DEMGKBKK_01069 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DEMGKBKK_01070 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DEMGKBKK_01071 9.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DEMGKBKK_01072 1.8e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DEMGKBKK_01073 1e-78 6.3.3.2 S ASCH
DEMGKBKK_01074 1.1e-306 recN L May be involved in recombinational repair of damaged DNA
DEMGKBKK_01075 8.1e-151 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DEMGKBKK_01076 3.6e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DEMGKBKK_01077 2.1e-22 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DEMGKBKK_01078 3.4e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DEMGKBKK_01079 6.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DEMGKBKK_01080 1.4e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DEMGKBKK_01081 2.4e-69 yqhY S Asp23 family, cell envelope-related function
DEMGKBKK_01082 1.4e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DEMGKBKK_01083 4.1e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DEMGKBKK_01084 1e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DEMGKBKK_01085 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
DEMGKBKK_01086 7.7e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
DEMGKBKK_01087 1.5e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
DEMGKBKK_01088 3.4e-123 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
DEMGKBKK_01089 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DEMGKBKK_01090 0.0 S Predicted membrane protein (DUF2207)
DEMGKBKK_01091 3.7e-200 M Glycosyl hydrolases family 25
DEMGKBKK_01093 6.1e-176 I Carboxylesterase family
DEMGKBKK_01094 2.3e-65 arsC 1.20.4.1 P Belongs to the ArsC family
DEMGKBKK_01095 4e-27
DEMGKBKK_01096 6.9e-62 S Bacterial PH domain
DEMGKBKK_01097 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DEMGKBKK_01098 1.4e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DEMGKBKK_01099 1.1e-46
DEMGKBKK_01100 1.3e-142 glcU U sugar transport
DEMGKBKK_01102 2.6e-38
DEMGKBKK_01103 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DEMGKBKK_01104 5.1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DEMGKBKK_01105 2.3e-240 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DEMGKBKK_01106 1.5e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DEMGKBKK_01107 2.3e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEMGKBKK_01108 8.5e-165 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DEMGKBKK_01109 4e-122 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DEMGKBKK_01110 8.2e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DEMGKBKK_01111 7e-11 S RelB antitoxin
DEMGKBKK_01112 1.8e-84 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
DEMGKBKK_01113 1.2e-178 tcsA S ABC transporter substrate-binding protein PnrA-like
DEMGKBKK_01114 2.3e-247 xylG 3.6.3.17 S ABC transporter
DEMGKBKK_01115 1.5e-166 yufP S Belongs to the binding-protein-dependent transport system permease family
DEMGKBKK_01116 1.7e-160 yufQ S Belongs to the binding-protein-dependent transport system permease family
DEMGKBKK_01117 0.0 3.6.3.8 P P-type ATPase
DEMGKBKK_01118 7.1e-207 G Major Facilitator Superfamily
DEMGKBKK_01119 1.8e-47
DEMGKBKK_01120 1.3e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
DEMGKBKK_01121 1.1e-145 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DEMGKBKK_01122 3.4e-52 S Iron-sulfur cluster assembly protein
DEMGKBKK_01123 4.8e-48 M NlpC/P60 family
DEMGKBKK_01124 2.2e-46 M NlpC/P60 family
DEMGKBKK_01125 9.1e-33 M NlpC/P60 family
DEMGKBKK_01126 7.4e-127 G Peptidase_C39 like family
DEMGKBKK_01127 3e-26
DEMGKBKK_01128 2.2e-122 F DNA/RNA non-specific endonuclease
DEMGKBKK_01129 2.1e-56 L nuclease
DEMGKBKK_01130 1.7e-19 S Metal binding domain of Ada
DEMGKBKK_01132 8.3e-31
DEMGKBKK_01134 8.5e-218 S SLAP domain
DEMGKBKK_01136 3.6e-142 mrr L restriction endonuclease
DEMGKBKK_01137 3.8e-220 S response to antibiotic
DEMGKBKK_01138 5e-90
DEMGKBKK_01141 1.8e-193 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
DEMGKBKK_01142 9.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DEMGKBKK_01143 1.3e-271 yjeM E Amino Acid
DEMGKBKK_01144 1.1e-201
DEMGKBKK_01145 6e-83
DEMGKBKK_01146 1.3e-125 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
DEMGKBKK_01147 1.6e-70 O OsmC-like protein
DEMGKBKK_01148 4.7e-208 EGP Major facilitator Superfamily
DEMGKBKK_01149 7.5e-57 sptS 2.7.13.3 T Histidine kinase
DEMGKBKK_01150 3.5e-99 sptS 2.7.13.3 T Histidine kinase
DEMGKBKK_01151 8.2e-51 2.7.6.5 T Region found in RelA / SpoT proteins
DEMGKBKK_01152 2.5e-23 2.7.6.5 T Region found in RelA / SpoT proteins
DEMGKBKK_01153 3.2e-245 S SLAP domain
DEMGKBKK_01154 3.8e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DEMGKBKK_01155 5.9e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DEMGKBKK_01156 2.6e-219 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DEMGKBKK_01157 3.3e-186 lacR K Transcriptional regulator
DEMGKBKK_01158 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
DEMGKBKK_01159 2.3e-167 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
DEMGKBKK_01160 7.5e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DEMGKBKK_01161 3.6e-79 L COG2963 Transposase and inactivated derivatives
DEMGKBKK_01162 4.4e-146
DEMGKBKK_01163 2.7e-163
DEMGKBKK_01164 1.9e-134
DEMGKBKK_01165 1.2e-260 glnA 6.3.1.2 E glutamine synthetase
DEMGKBKK_01166 3.3e-169 ynbB 4.4.1.1 P aluminum resistance
DEMGKBKK_01167 1e-33 ynbB 4.4.1.1 P aluminum resistance
DEMGKBKK_01168 6.7e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DEMGKBKK_01169 1.5e-68 yqhL P Rhodanese-like protein
DEMGKBKK_01170 5.6e-33 yqgQ S Bacterial protein of unknown function (DUF910)
DEMGKBKK_01171 2.7e-115 gluP 3.4.21.105 S Rhomboid family
DEMGKBKK_01172 2.5e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DEMGKBKK_01173 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DEMGKBKK_01174 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
DEMGKBKK_01175 0.0 S membrane
DEMGKBKK_01176 3.1e-167 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
DEMGKBKK_01177 3.8e-63 L Transposase
DEMGKBKK_01178 4.7e-115 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DEMGKBKK_01179 3e-99 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DEMGKBKK_01180 1.1e-128 znuB U ABC 3 transport family
DEMGKBKK_01181 2.3e-116 fhuC P ABC transporter
DEMGKBKK_01182 6e-155 psaA P Belongs to the bacterial solute-binding protein 9 family
DEMGKBKK_01183 1.1e-40 K helix_turn_helix, Arsenical Resistance Operon Repressor
DEMGKBKK_01184 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
DEMGKBKK_01185 6.3e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
DEMGKBKK_01186 1.2e-138 fruR K DeoR C terminal sensor domain
DEMGKBKK_01189 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
DEMGKBKK_01190 8.7e-27
DEMGKBKK_01191 7.1e-33
DEMGKBKK_01192 1.9e-33 yozG K Transcriptional regulator
DEMGKBKK_01193 4.8e-54 S Enterocin A Immunity
DEMGKBKK_01194 1.4e-12 S Enterocin A Immunity
DEMGKBKK_01195 1.4e-194 S Archaea bacterial proteins of unknown function
DEMGKBKK_01196 1.5e-135 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
DEMGKBKK_01197 3.2e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DEMGKBKK_01198 1.7e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
DEMGKBKK_01199 1.6e-120 K response regulator
DEMGKBKK_01200 0.0 V ABC transporter
DEMGKBKK_01201 1.5e-295 V ABC transporter, ATP-binding protein
DEMGKBKK_01202 6.4e-137 XK27_01040 S Protein of unknown function (DUF1129)
DEMGKBKK_01203 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DEMGKBKK_01204 1.4e-43 yyzM S Bacterial protein of unknown function (DUF951)
DEMGKBKK_01205 5e-154 spo0J K Belongs to the ParB family
DEMGKBKK_01206 1.1e-136 soj D Sporulation initiation inhibitor
DEMGKBKK_01207 1.2e-146 noc K Belongs to the ParB family
DEMGKBKK_01208 1.6e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DEMGKBKK_01209 3.6e-83 cvpA S Colicin V production protein
DEMGKBKK_01210 8.6e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DEMGKBKK_01211 2.5e-149 3.1.3.48 T Tyrosine phosphatase family
DEMGKBKK_01212 5e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
DEMGKBKK_01213 1.8e-93 nqr 1.5.1.36 S NADPH-dependent FMN reductase
DEMGKBKK_01214 1.2e-109 K WHG domain
DEMGKBKK_01215 8e-38
DEMGKBKK_01216 3.9e-270 pipD E Dipeptidase
DEMGKBKK_01217 1.1e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
DEMGKBKK_01218 3.1e-166 hrtB V ABC transporter permease
DEMGKBKK_01219 7e-95 ygfC K Bacterial regulatory proteins, tetR family
DEMGKBKK_01220 7.9e-111 G phosphoglycerate mutase
DEMGKBKK_01221 5e-139 aroD S Alpha/beta hydrolase family
DEMGKBKK_01222 3e-139 S Belongs to the UPF0246 family
DEMGKBKK_01223 1.7e-119
DEMGKBKK_01224 2.7e-151 2.7.7.12 C Domain of unknown function (DUF4931)
DEMGKBKK_01225 1.4e-183 S Putative peptidoglycan binding domain
DEMGKBKK_01226 1.8e-24
DEMGKBKK_01227 5.9e-248 dtpT U amino acid peptide transporter
DEMGKBKK_01228 0.0 pepN 3.4.11.2 E aminopeptidase
DEMGKBKK_01229 5.3e-57 lysM M LysM domain
DEMGKBKK_01230 2.5e-170
DEMGKBKK_01231 6e-214 mdtG EGP Major facilitator Superfamily
DEMGKBKK_01232 2.4e-228 L Transposase
DEMGKBKK_01233 1.8e-13 ytgB S Transglycosylase associated protein
DEMGKBKK_01234 5.9e-52 K helix_turn_helix gluconate operon transcriptional repressor
DEMGKBKK_01235 2.7e-97 yieF S NADPH-dependent FMN reductase
DEMGKBKK_01236 1.2e-09 ymdB S Macro domain protein
DEMGKBKK_01237 1.6e-152 malG P ABC transporter permease
DEMGKBKK_01238 5.9e-247 malF P Binding-protein-dependent transport system inner membrane component
DEMGKBKK_01239 1.4e-210 malE G Bacterial extracellular solute-binding protein
DEMGKBKK_01240 8.3e-207 msmX P Belongs to the ABC transporter superfamily
DEMGKBKK_01241 4.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
DEMGKBKK_01242 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
DEMGKBKK_01243 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
DEMGKBKK_01244 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
DEMGKBKK_01245 2.9e-150 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEMGKBKK_01246 3e-173 yvdE K helix_turn _helix lactose operon repressor
DEMGKBKK_01247 3e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
DEMGKBKK_01248 6.2e-166 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEMGKBKK_01249 4.8e-85 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DEMGKBKK_01250 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DEMGKBKK_01252 9.3e-132 cobQ S glutamine amidotransferase
DEMGKBKK_01253 2.3e-81 M NlpC/P60 family
DEMGKBKK_01254 5.4e-151 EG EamA-like transporter family
DEMGKBKK_01255 9.3e-156 EG EamA-like transporter family
DEMGKBKK_01256 1.1e-107
DEMGKBKK_01257 2e-75
DEMGKBKK_01258 1.5e-113 XK27_05540 S DUF218 domain
DEMGKBKK_01259 7.4e-181 yheS_2 S ATPases associated with a variety of cellular activities
DEMGKBKK_01260 2e-80
DEMGKBKK_01261 8.8e-57
DEMGKBKK_01262 7.6e-244 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DEMGKBKK_01263 3.3e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DEMGKBKK_01264 5.7e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DEMGKBKK_01267 2.2e-201 4.2.1.126 S Bacterial protein of unknown function (DUF871)
DEMGKBKK_01268 2.2e-190 asnA 6.3.1.1 F aspartate--ammonia ligase
DEMGKBKK_01269 2.2e-236 steT_1 E amino acid
DEMGKBKK_01270 4.1e-138 puuD S peptidase C26
DEMGKBKK_01271 8.6e-246 yifK E Amino acid permease
DEMGKBKK_01272 4.1e-216 cycA E Amino acid permease
DEMGKBKK_01273 2e-127
DEMGKBKK_01274 9.3e-118 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DEMGKBKK_01275 0.0 clpE O AAA domain (Cdc48 subfamily)
DEMGKBKK_01276 3.7e-168 S Alpha/beta hydrolase of unknown function (DUF915)
DEMGKBKK_01277 3.4e-223 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMGKBKK_01278 1.4e-119 XK27_06785 V ABC transporter, ATP-binding protein
DEMGKBKK_01279 2.2e-164 XK27_06780 V ABC transporter permease
DEMGKBKK_01280 3.6e-35
DEMGKBKK_01281 1.8e-282 ytgP S Polysaccharide biosynthesis protein
DEMGKBKK_01282 1.8e-149 lysA2 M Glycosyl hydrolases family 25
DEMGKBKK_01283 8.5e-122 S Protein of unknown function (DUF975)
DEMGKBKK_01284 1.7e-41
DEMGKBKK_01285 4.4e-81 S CAAX protease self-immunity
DEMGKBKK_01286 1.2e-10
DEMGKBKK_01287 5.1e-173 pbpX2 V Beta-lactamase
DEMGKBKK_01288 1e-248 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DEMGKBKK_01289 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEMGKBKK_01290 9.2e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
DEMGKBKK_01291 1.4e-292 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DEMGKBKK_01292 2.6e-18 S D-Ala-teichoic acid biosynthesis protein
DEMGKBKK_01293 3.2e-49
DEMGKBKK_01294 9.4e-214 ywhK S Membrane
DEMGKBKK_01295 3.9e-81 ykuL S (CBS) domain
DEMGKBKK_01296 0.0 cadA P P-type ATPase
DEMGKBKK_01297 7.2e-201 napA P Sodium/hydrogen exchanger family
DEMGKBKK_01298 1.7e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
DEMGKBKK_01299 1.6e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
DEMGKBKK_01300 2.5e-281 V ABC transporter transmembrane region
DEMGKBKK_01301 2.5e-66 S Putative adhesin
DEMGKBKK_01302 1e-151 mutR K Helix-turn-helix XRE-family like proteins
DEMGKBKK_01303 8.4e-39
DEMGKBKK_01304 4.3e-118 S CAAX protease self-immunity
DEMGKBKK_01305 3.4e-192 S DUF218 domain
DEMGKBKK_01306 0.0 macB_3 V ABC transporter, ATP-binding protein
DEMGKBKK_01307 2.9e-97 S ECF transporter, substrate-specific component
DEMGKBKK_01308 1.7e-159 yeaE S Aldo/keto reductase family
DEMGKBKK_01309 2.2e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DEMGKBKK_01310 1.8e-07 ybbH_2 K rpiR family
DEMGKBKK_01311 2.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DEMGKBKK_01312 1.5e-126 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DEMGKBKK_01313 7.7e-146 cof S haloacid dehalogenase-like hydrolase
DEMGKBKK_01314 9.1e-229 pbuG S permease
DEMGKBKK_01315 6.5e-38 S cog cog1373
DEMGKBKK_01316 1.6e-150 S cog cog1373
DEMGKBKK_01317 1.3e-131 K helix_turn_helix, mercury resistance
DEMGKBKK_01318 1.7e-227 pbuG S permease
DEMGKBKK_01319 3.7e-244 S Uncharacterised protein family (UPF0236)
DEMGKBKK_01320 9.8e-239 amtB P ammonium transporter
DEMGKBKK_01321 1.5e-223 pbuG S permease
DEMGKBKK_01322 5.1e-35
DEMGKBKK_01323 2.7e-76 atkY K Penicillinase repressor
DEMGKBKK_01324 2e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DEMGKBKK_01325 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DEMGKBKK_01326 0.0 copA 3.6.3.54 P P-type ATPase
DEMGKBKK_01327 8.2e-25 S CAAX protease self-immunity
DEMGKBKK_01328 1.3e-17
DEMGKBKK_01329 8.8e-209
DEMGKBKK_01330 1.8e-279 clcA P chloride
DEMGKBKK_01331 2.1e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DEMGKBKK_01332 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
DEMGKBKK_01333 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DEMGKBKK_01334 3.6e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DEMGKBKK_01335 3.9e-143 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEMGKBKK_01336 3.9e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DEMGKBKK_01337 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DEMGKBKK_01338 4.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DEMGKBKK_01339 3.3e-195 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DEMGKBKK_01340 1.7e-34 yaaA S S4 domain protein YaaA
DEMGKBKK_01341 9e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DEMGKBKK_01342 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEMGKBKK_01343 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DEMGKBKK_01344 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
DEMGKBKK_01345 7.9e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DEMGKBKK_01346 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DEMGKBKK_01347 1.1e-31 S SLAP domain
DEMGKBKK_01348 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DEMGKBKK_01349 2.2e-68 rplI J Binds to the 23S rRNA
DEMGKBKK_01350 2.7e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DEMGKBKK_01351 4.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
DEMGKBKK_01352 5e-173 degV S DegV family
DEMGKBKK_01353 1.9e-42 L transposase, IS605 OrfB family
DEMGKBKK_01354 1.5e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DEMGKBKK_01355 1e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DEMGKBKK_01356 3.2e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DEMGKBKK_01357 4.4e-24
DEMGKBKK_01358 1.1e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DEMGKBKK_01359 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DEMGKBKK_01360 2.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DEMGKBKK_01361 6.5e-133 comFC S Competence protein
DEMGKBKK_01362 4.7e-246 comFA L Helicase C-terminal domain protein
DEMGKBKK_01363 4.5e-115 yvyE 3.4.13.9 S YigZ family
DEMGKBKK_01364 2.5e-206 tagO 2.7.8.33, 2.7.8.35 M transferase
DEMGKBKK_01365 5.8e-217 rny S Endoribonuclease that initiates mRNA decay
DEMGKBKK_01366 1.4e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DEMGKBKK_01367 1.9e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DEMGKBKK_01368 1.5e-139 ymfM S Helix-turn-helix domain
DEMGKBKK_01369 4e-133 IQ Enoyl-(Acyl carrier protein) reductase
DEMGKBKK_01370 1.1e-234 S Peptidase M16
DEMGKBKK_01371 7.9e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
DEMGKBKK_01372 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DEMGKBKK_01373 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
DEMGKBKK_01374 5.5e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DEMGKBKK_01375 7.3e-209 yubA S AI-2E family transporter
DEMGKBKK_01376 1.9e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
DEMGKBKK_01377 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
DEMGKBKK_01378 7.5e-202 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
DEMGKBKK_01379 1.3e-109 S SNARE associated Golgi protein
DEMGKBKK_01380 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
DEMGKBKK_01381 1.5e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DEMGKBKK_01382 6e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DEMGKBKK_01383 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
DEMGKBKK_01384 1.2e-109 yjbK S CYTH
DEMGKBKK_01385 7.7e-100 yjbH Q Thioredoxin
DEMGKBKK_01386 5e-159 coiA 3.6.4.12 S Competence protein
DEMGKBKK_01387 1.1e-133 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DEMGKBKK_01388 2.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DEMGKBKK_01389 5.5e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DEMGKBKK_01390 8.5e-41 ptsH G phosphocarrier protein HPR
DEMGKBKK_01391 5.1e-27
DEMGKBKK_01392 0.0 clpE O Belongs to the ClpA ClpB family
DEMGKBKK_01393 2.5e-43 XK27_09445 S Domain of unknown function (DUF1827)
DEMGKBKK_01394 5.4e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DEMGKBKK_01395 8.6e-159 hlyX S Transporter associated domain
DEMGKBKK_01396 2.5e-72
DEMGKBKK_01397 1.9e-86
DEMGKBKK_01398 1.9e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
DEMGKBKK_01399 4.7e-260 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DEMGKBKK_01400 1.7e-47 tnpR1 L Resolvase, N terminal domain
DEMGKBKK_01401 1.5e-53 tnpR1 L Resolvase, N terminal domain
DEMGKBKK_01402 2.3e-19
DEMGKBKK_01405 1.7e-36
DEMGKBKK_01406 1.3e-20
DEMGKBKK_01407 1.4e-20 S DNA primase
DEMGKBKK_01408 1.4e-203 L COG2826 Transposase and inactivated derivatives, IS30 family
DEMGKBKK_01411 6e-97 L An automated process has identified a potential problem with this gene model
DEMGKBKK_01412 5.5e-46
DEMGKBKK_01413 1e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
DEMGKBKK_01414 7.6e-223 L transposase, IS605 OrfB family
DEMGKBKK_01415 2.3e-167 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DEMGKBKK_01416 1.1e-151 yihY S Belongs to the UPF0761 family
DEMGKBKK_01417 1.7e-164 map 3.4.11.18 E Methionine Aminopeptidase
DEMGKBKK_01418 1.3e-78 fld C Flavodoxin
DEMGKBKK_01419 5.3e-90 gtcA S Teichoic acid glycosylation protein
DEMGKBKK_01420 3.2e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DEMGKBKK_01421 7.9e-25
DEMGKBKK_01423 3.9e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMGKBKK_01424 1.2e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
DEMGKBKK_01425 3.7e-128 M Glycosyl hydrolases family 25
DEMGKBKK_01426 4.2e-226 potE E amino acid
DEMGKBKK_01427 6.3e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DEMGKBKK_01428 1.6e-236 yhdP S Transporter associated domain
DEMGKBKK_01429 5.2e-10 C nitroreductase
DEMGKBKK_01430 2.5e-18 C nitroreductase
DEMGKBKK_01431 6.2e-39
DEMGKBKK_01432 1.2e-85 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
DEMGKBKK_01433 8.3e-74
DEMGKBKK_01434 5e-30 glvR K Helix-turn-helix domain, rpiR family
DEMGKBKK_01435 7e-60 glvR K Helix-turn-helix domain, rpiR family
DEMGKBKK_01436 0.0 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
DEMGKBKK_01437 2.4e-85 S hydrolase
DEMGKBKK_01438 1.5e-160 rssA S Phospholipase, patatin family
DEMGKBKK_01439 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
DEMGKBKK_01440 1.1e-134 glcR K DeoR C terminal sensor domain
DEMGKBKK_01441 2.7e-58 S Enterocin A Immunity
DEMGKBKK_01442 4.3e-152 S hydrolase
DEMGKBKK_01443 5.7e-132 gntR K UbiC transcription regulator-associated domain protein
DEMGKBKK_01444 4.8e-176 rihB 3.2.2.1 F Nucleoside
DEMGKBKK_01445 0.0 kup P Transport of potassium into the cell
DEMGKBKK_01446 2.6e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DEMGKBKK_01447 1e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DEMGKBKK_01448 2.2e-161 2.7.7.12 C Domain of unknown function (DUF4931)
DEMGKBKK_01449 6.7e-232 G Bacterial extracellular solute-binding protein
DEMGKBKK_01450 2.9e-90 S SLAP domain
DEMGKBKK_01451 2.6e-25 S Protein of unknown function (DUF2974)
DEMGKBKK_01452 1e-24 S Protein of unknown function (DUF2974)
DEMGKBKK_01453 4.7e-74 S Protein of unknown function (DUF2974)
DEMGKBKK_01454 7.5e-107 glnP P ABC transporter permease
DEMGKBKK_01455 5.1e-108 gluC P ABC transporter permease
DEMGKBKK_01456 9e-150 glnH ET ABC transporter substrate-binding protein
DEMGKBKK_01457 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DEMGKBKK_01458 1.5e-112 udk 2.7.1.48 F Zeta toxin
DEMGKBKK_01459 1.2e-190 EGP Major facilitator superfamily
DEMGKBKK_01460 9.3e-101 S ABC-type cobalt transport system, permease component
DEMGKBKK_01461 0.0 V ABC transporter transmembrane region
DEMGKBKK_01462 2e-287 XK27_09600 V ABC transporter, ATP-binding protein
DEMGKBKK_01463 5.1e-81 K Transcriptional regulator, MarR family
DEMGKBKK_01464 1.6e-146 glnH ET ABC transporter
DEMGKBKK_01465 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
DEMGKBKK_01466 1.4e-56
DEMGKBKK_01467 2.7e-29
DEMGKBKK_01468 1.9e-308 ybiT S ABC transporter, ATP-binding protein
DEMGKBKK_01469 3.9e-209 pepA E M42 glutamyl aminopeptidase
DEMGKBKK_01470 9.6e-217 mdtG EGP Major facilitator Superfamily
DEMGKBKK_01471 1.5e-259 emrY EGP Major facilitator Superfamily
DEMGKBKK_01472 2e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DEMGKBKK_01473 8.9e-240 pyrP F Permease
DEMGKBKK_01474 4.4e-29
DEMGKBKK_01475 6e-28 L COG2963 Transposase and inactivated derivatives
DEMGKBKK_01476 7e-46
DEMGKBKK_01477 1.2e-53 S Domain of unknown function (DUF5067)
DEMGKBKK_01478 1.4e-62
DEMGKBKK_01479 5e-47
DEMGKBKK_01480 5.3e-144 2.4.2.3 F Phosphorylase superfamily
DEMGKBKK_01481 3.9e-30 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
DEMGKBKK_01482 2.5e-30 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
DEMGKBKK_01484 2.2e-35 K Acetyltransferase (GNAT) domain
DEMGKBKK_01485 6.6e-46
DEMGKBKK_01486 6e-134
DEMGKBKK_01487 9e-181 EGP Major facilitator Superfamily
DEMGKBKK_01488 5.5e-101
DEMGKBKK_01489 2.2e-50 S Fic/DOC family
DEMGKBKK_01490 8.6e-60 S Fic/DOC family
DEMGKBKK_01491 2e-55
DEMGKBKK_01492 3.3e-87
DEMGKBKK_01493 1.3e-58 ypaA S Protein of unknown function (DUF1304)
DEMGKBKK_01494 2.5e-66 S Putative adhesin
DEMGKBKK_01495 6.3e-293 V ABC-type multidrug transport system, ATPase and permease components
DEMGKBKK_01496 5.6e-289 P ABC transporter
DEMGKBKK_01497 9.7e-61
DEMGKBKK_01498 3.1e-57 fic D Fic/DOC family
DEMGKBKK_01499 7e-17 fic D Fic/DOC family
DEMGKBKK_01500 9.4e-33
DEMGKBKK_01501 4.7e-254 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DEMGKBKK_01502 2.5e-234 mepA V MATE efflux family protein
DEMGKBKK_01503 1.2e-18 S SLAP domain
DEMGKBKK_01505 0.0 1.3.5.4 C FAD binding domain
DEMGKBKK_01506 9.5e-65 K Helix-turn-helix XRE-family like proteins
DEMGKBKK_01507 7.6e-62 K Helix-turn-helix XRE-family like proteins
DEMGKBKK_01508 1.6e-49 K Helix-turn-helix XRE-family like proteins
DEMGKBKK_01509 7.4e-117
DEMGKBKK_01511 1e-83 S Protein of unknown function (DUF3232)
DEMGKBKK_01512 1.9e-84 D nuclear chromosome segregation
DEMGKBKK_01513 2.9e-175 S SLAP domain
DEMGKBKK_01514 6.4e-111 K Helix-turn-helix XRE-family like proteins
DEMGKBKK_01515 4.6e-124
DEMGKBKK_01516 3.3e-65
DEMGKBKK_01517 1.2e-27 K Helix-turn-helix XRE-family like proteins
DEMGKBKK_01518 5.4e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DEMGKBKK_01519 1.2e-141 K Helix-turn-helix domain
DEMGKBKK_01520 1.3e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DEMGKBKK_01521 1.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
DEMGKBKK_01522 1.7e-280 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DEMGKBKK_01523 2e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DEMGKBKK_01524 1.9e-80 yueI S Protein of unknown function (DUF1694)
DEMGKBKK_01525 4.4e-239 rarA L recombination factor protein RarA
DEMGKBKK_01526 2.5e-35
DEMGKBKK_01527 2.3e-78 usp6 T universal stress protein
DEMGKBKK_01528 1.9e-217 rodA D Belongs to the SEDS family
DEMGKBKK_01529 2.5e-33 S Protein of unknown function (DUF2969)
DEMGKBKK_01530 7.2e-49 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DEMGKBKK_01531 3e-176 mbl D Cell shape determining protein MreB Mrl
DEMGKBKK_01532 3.4e-30 ywzB S Protein of unknown function (DUF1146)
DEMGKBKK_01533 2.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DEMGKBKK_01534 3.5e-242 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DEMGKBKK_01535 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DEMGKBKK_01536 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DEMGKBKK_01537 4.9e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEMGKBKK_01538 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DEMGKBKK_01539 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DEMGKBKK_01540 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
DEMGKBKK_01541 2.6e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DEMGKBKK_01542 2.7e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DEMGKBKK_01543 3.9e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DEMGKBKK_01544 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DEMGKBKK_01545 2.2e-113 tdk 2.7.1.21 F thymidine kinase
DEMGKBKK_01546 1e-246 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
DEMGKBKK_01549 4.6e-196 ampC V Beta-lactamase
DEMGKBKK_01550 8.3e-134 EGP Major facilitator Superfamily
DEMGKBKK_01551 3.2e-21 EGP Major facilitator Superfamily
DEMGKBKK_01552 1.1e-15 EGP Major facilitator Superfamily
DEMGKBKK_01553 9.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
DEMGKBKK_01554 8.3e-108 vanZ V VanZ like family
DEMGKBKK_01555 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DEMGKBKK_01556 6.9e-270 yclK 2.7.13.3 T Histidine kinase
DEMGKBKK_01557 3.5e-129 K Transcriptional regulatory protein, C terminal
DEMGKBKK_01558 7.1e-60 S SdpI/YhfL protein family
DEMGKBKK_01559 1.7e-168 manA 5.3.1.8 G mannose-6-phosphate isomerase
DEMGKBKK_01560 8.1e-171 patB 4.4.1.8 E Aminotransferase, class I
DEMGKBKK_01561 1.1e-36 patB 4.4.1.8 E Aminotransferase, class I
DEMGKBKK_01562 5e-67 M Protein of unknown function (DUF3737)
DEMGKBKK_01564 6.8e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEMGKBKK_01565 5.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
DEMGKBKK_01566 7.8e-80 comGF U Putative Competence protein ComGF
DEMGKBKK_01567 1.7e-41
DEMGKBKK_01568 2.1e-73
DEMGKBKK_01569 1.4e-43 comGC U competence protein ComGC
DEMGKBKK_01570 1.9e-173 comGB NU type II secretion system
DEMGKBKK_01571 2.3e-176 comGA NU Type II IV secretion system protein
DEMGKBKK_01572 2.6e-132 yebC K Transcriptional regulatory protein
DEMGKBKK_01573 4.3e-89 S VanZ like family
DEMGKBKK_01574 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DEMGKBKK_01576 1.5e-289 E Amino acid permease
DEMGKBKK_01577 4e-181 D Alpha beta
DEMGKBKK_01578 5e-300 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEMGKBKK_01579 0.0 bglP G phosphotransferase system
DEMGKBKK_01580 1.8e-142 licT K CAT RNA binding domain
DEMGKBKK_01581 6.2e-213 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DEMGKBKK_01582 4.9e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DEMGKBKK_01583 1.9e-116
DEMGKBKK_01584 5.4e-147 S Sucrose-6F-phosphate phosphohydrolase
DEMGKBKK_01585 5.8e-149 S hydrolase
DEMGKBKK_01586 5.3e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DEMGKBKK_01587 2.8e-171 ybbR S YbbR-like protein
DEMGKBKK_01588 1.2e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DEMGKBKK_01589 3.4e-205 potD P ABC transporter
DEMGKBKK_01590 1.4e-123 potC P ABC transporter permease
DEMGKBKK_01591 7.9e-130 potB P ABC transporter permease
DEMGKBKK_01592 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DEMGKBKK_01593 7e-164 murB 1.3.1.98 M Cell wall formation
DEMGKBKK_01594 1.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
DEMGKBKK_01595 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
DEMGKBKK_01596 7.3e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DEMGKBKK_01597 1.7e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DEMGKBKK_01598 7.7e-152 ycsE S Sucrose-6F-phosphate phosphohydrolase
DEMGKBKK_01599 5.3e-95
DEMGKBKK_01600 1.2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DEMGKBKK_01601 2.7e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DEMGKBKK_01602 1.9e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DEMGKBKK_01603 1.2e-188 cggR K Putative sugar-binding domain
DEMGKBKK_01605 6.5e-142
DEMGKBKK_01606 1.6e-63
DEMGKBKK_01607 2.2e-33
DEMGKBKK_01608 1e-146 ycaM E amino acid
DEMGKBKK_01609 3.4e-49 ycaM E amino acid
DEMGKBKK_01610 3.6e-151 S haloacid dehalogenase-like hydrolase
DEMGKBKK_01611 0.0 S SH3-like domain
DEMGKBKK_01612 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DEMGKBKK_01613 1.1e-170 whiA K May be required for sporulation
DEMGKBKK_01614 5.4e-192 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DEMGKBKK_01615 3.1e-164 rapZ S Displays ATPase and GTPase activities
DEMGKBKK_01616 4.5e-81 S Short repeat of unknown function (DUF308)
DEMGKBKK_01617 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DEMGKBKK_01618 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DEMGKBKK_01619 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DEMGKBKK_01620 2e-61 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DEMGKBKK_01621 3e-43 L transposase, IS605 OrfB family
DEMGKBKK_01624 8e-168 psaA P Belongs to the bacterial solute-binding protein 9 family
DEMGKBKK_01627 4.3e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DEMGKBKK_01628 1.6e-261 qacA EGP Major facilitator Superfamily
DEMGKBKK_01629 9.9e-12 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DEMGKBKK_01630 1.4e-64 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DEMGKBKK_01631 4.8e-52 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DEMGKBKK_01632 5.6e-118 3.6.1.27 I Acid phosphatase homologues
DEMGKBKK_01633 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DEMGKBKK_01634 1e-293 ytgP S Polysaccharide biosynthesis protein
DEMGKBKK_01635 7.2e-09 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
DEMGKBKK_01636 2.2e-154 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
DEMGKBKK_01637 7.6e-23 dhaL 2.7.1.121 S Dak2
DEMGKBKK_01638 5.1e-68 infB UW LPXTG-motif cell wall anchor domain protein
DEMGKBKK_01639 9.4e-52 infB UW LPXTG-motif cell wall anchor domain protein
DEMGKBKK_01641 2.1e-20
DEMGKBKK_01642 2e-58 CO Thioredoxin
DEMGKBKK_01643 2e-115 M1-798 K Rhodanese Homology Domain
DEMGKBKK_01644 3.5e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DEMGKBKK_01645 7.3e-16 frnE Q DSBA-like thioredoxin domain
DEMGKBKK_01646 5.5e-52 frnE Q DSBA-like thioredoxin domain
DEMGKBKK_01647 2.5e-31 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DEMGKBKK_01648 3.5e-138 yxeH S hydrolase
DEMGKBKK_01649 1.9e-37 S Enterocin A Immunity
DEMGKBKK_01650 2.6e-90 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
DEMGKBKK_01651 3.6e-96 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
DEMGKBKK_01652 4.4e-49 pspC KT PspC domain
DEMGKBKK_01654 6.9e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DEMGKBKK_01655 3.1e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DEMGKBKK_01656 3.1e-108 M ErfK YbiS YcfS YnhG
DEMGKBKK_01657 3e-90 padR K Virulence activator alpha C-term
DEMGKBKK_01658 6.2e-105 padC Q Phenolic acid decarboxylase
DEMGKBKK_01659 4.5e-106 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DEMGKBKK_01660 8.7e-11 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DEMGKBKK_01661 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DEMGKBKK_01662 1e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
DEMGKBKK_01663 1.9e-46 3.6.1.55 L NUDIX domain
DEMGKBKK_01664 8.1e-39
DEMGKBKK_01665 1.1e-30
DEMGKBKK_01666 4.7e-95 2.7.13.3 T GHKL domain
DEMGKBKK_01667 2.7e-143 K LytTr DNA-binding domain
DEMGKBKK_01668 1.1e-110 M LysM domain
DEMGKBKK_01669 4.4e-101
DEMGKBKK_01670 2.9e-114 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
DEMGKBKK_01671 3.2e-106
DEMGKBKK_01672 8.2e-27
DEMGKBKK_01673 1.6e-89 S GyrI-like small molecule binding domain
DEMGKBKK_01674 4.8e-17 yniG EGP Major facilitator Superfamily
DEMGKBKK_01675 2.1e-82 racA K Domain of unknown function (DUF1836)
DEMGKBKK_01676 1.6e-149 yitS S EDD domain protein, DegV family
DEMGKBKK_01677 1.3e-48
DEMGKBKK_01678 2.6e-42
DEMGKBKK_01679 1.3e-213 L transposase, IS605 OrfB family
DEMGKBKK_01680 1.9e-147 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
DEMGKBKK_01681 9.8e-55
DEMGKBKK_01682 2.4e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEMGKBKK_01683 7.8e-252 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMGKBKK_01684 7.3e-138 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DEMGKBKK_01685 3.2e-84 mgtC S MgtC family
DEMGKBKK_01686 2.5e-09 5.3.3.2 C FMN-dependent dehydrogenase
DEMGKBKK_01687 8.2e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DEMGKBKK_01688 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DEMGKBKK_01689 9.4e-56 yheA S Belongs to the UPF0342 family
DEMGKBKK_01690 2.9e-229 yhaO L Ser Thr phosphatase family protein
DEMGKBKK_01691 0.0 L AAA domain
DEMGKBKK_01692 1.3e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
DEMGKBKK_01693 3.5e-155 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DEMGKBKK_01694 3.3e-26
DEMGKBKK_01695 3.1e-80 hit FG Scavenger mRNA decapping enzyme C-term binding
DEMGKBKK_01696 2.3e-34 S Plasmid maintenance system killer
DEMGKBKK_01697 1.4e-53 higA K Helix-turn-helix XRE-family like proteins
DEMGKBKK_01698 1.1e-135 ecsA V ABC transporter, ATP-binding protein
DEMGKBKK_01699 2.9e-213 ecsB U ABC transporter
DEMGKBKK_01700 2.6e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DEMGKBKK_01701 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DEMGKBKK_01702 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DEMGKBKK_01703 3.4e-260
DEMGKBKK_01706 4e-60 S Psort location Cytoplasmic, score
DEMGKBKK_01707 9.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DEMGKBKK_01708 4.2e-68 M Peptidase family M1 domain
DEMGKBKK_01709 6.1e-103 M Peptidase family M1 domain
DEMGKBKK_01710 1.7e-40 L RelB antitoxin
DEMGKBKK_01711 8.5e-130 qmcA O prohibitin homologues
DEMGKBKK_01712 4.1e-16
DEMGKBKK_01713 8.1e-14
DEMGKBKK_01715 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DEMGKBKK_01716 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DEMGKBKK_01717 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DEMGKBKK_01718 1.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DEMGKBKK_01719 8.9e-248 dnaB L Replication initiation and membrane attachment
DEMGKBKK_01720 2.9e-165 dnaI L Primosomal protein DnaI
DEMGKBKK_01721 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DEMGKBKK_01722 1.8e-24 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
DEMGKBKK_01723 4.9e-101 S Domain of unknown function (DUF389)
DEMGKBKK_01724 9.3e-30 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
DEMGKBKK_01725 5.5e-239 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
DEMGKBKK_01726 4.8e-55 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DEMGKBKK_01727 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DEMGKBKK_01728 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DEMGKBKK_01729 3.8e-93 yqeG S HAD phosphatase, family IIIA
DEMGKBKK_01730 1.5e-211 yqeH S Ribosome biogenesis GTPase YqeH
DEMGKBKK_01731 4.1e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DEMGKBKK_01732 9.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
DEMGKBKK_01733 6.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DEMGKBKK_01734 4.3e-214 ylbM S Belongs to the UPF0348 family
DEMGKBKK_01735 1.5e-95 yceD S Uncharacterized ACR, COG1399
DEMGKBKK_01736 1e-125 K response regulator
DEMGKBKK_01737 4.3e-278 arlS 2.7.13.3 T Histidine kinase
DEMGKBKK_01738 1.3e-84 S Aminoacyl-tRNA editing domain
DEMGKBKK_01739 4.1e-154 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DEMGKBKK_01740 2.4e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DEMGKBKK_01741 1.1e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DEMGKBKK_01742 1.5e-61 yodB K Transcriptional regulator, HxlR family
DEMGKBKK_01743 1.5e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DEMGKBKK_01744 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DEMGKBKK_01745 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DEMGKBKK_01746 3.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
DEMGKBKK_01747 4.9e-22 S Phage derived protein Gp49-like (DUF891)
DEMGKBKK_01748 5.3e-38 K Helix-turn-helix domain
DEMGKBKK_01749 2.3e-43 L transposase, IS605 OrfB family
DEMGKBKK_01750 9e-14 S C4-dicarboxylate anaerobic carrier
DEMGKBKK_01751 1.5e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DEMGKBKK_01752 5.3e-23
DEMGKBKK_01753 1.7e-99 S LexA-binding, inner membrane-associated putative hydrolase
DEMGKBKK_01754 3e-37
DEMGKBKK_01755 6.7e-187 tdh 1.1.1.14 C Zinc-binding dehydrogenase
DEMGKBKK_01758 2e-28 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
DEMGKBKK_01759 3.7e-54 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
DEMGKBKK_01760 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
DEMGKBKK_01761 1.2e-185 V Beta-lactamase
DEMGKBKK_01762 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DEMGKBKK_01763 1.4e-49 K HxlR-like helix-turn-helix
DEMGKBKK_01764 6.9e-43 yqiG C Oxidoreductase
DEMGKBKK_01765 7.3e-50 yqiG C Oxidoreductase
DEMGKBKK_01766 1.1e-66 yqiG C Oxidoreductase
DEMGKBKK_01767 3.7e-19 I carboxylic ester hydrolase activity
DEMGKBKK_01768 1.4e-55 I carboxylic ester hydrolase activity
DEMGKBKK_01769 1.2e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DEMGKBKK_01770 2.2e-28 1.1.1.3 T phosphoserine phosphatase activity
DEMGKBKK_01771 6.7e-68 XK27_08635 S UPF0210 protein
DEMGKBKK_01772 1.1e-52 XK27_08635 S UPF0210 protein
DEMGKBKK_01773 2.5e-11 snf 2.7.11.1 KL domain protein
DEMGKBKK_01774 4.9e-50 snf 2.7.11.1 KL domain protein
DEMGKBKK_01775 2.3e-158 snf 2.7.11.1 KL domain protein
DEMGKBKK_01776 7.3e-202 snf 2.7.11.1 KL domain protein
DEMGKBKK_01777 4.7e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DEMGKBKK_01778 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DEMGKBKK_01779 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DEMGKBKK_01780 1.5e-167 K Transcriptional regulator
DEMGKBKK_01781 2.8e-163 ppaC 3.6.1.1 C inorganic pyrophosphatase
DEMGKBKK_01782 5.9e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DEMGKBKK_01783 6.8e-54 K Helix-turn-helix domain
DEMGKBKK_01784 6.7e-57 yoaK S Protein of unknown function (DUF1275)
DEMGKBKK_01785 1.2e-33 M Glycosyl hydrolases family 25
DEMGKBKK_01786 4.2e-78 M Glycosyl hydrolases family 25
DEMGKBKK_01787 2.4e-27 M Glycosyl hydrolases family 25
DEMGKBKK_01788 6.9e-17 XK27_00160 S Domain of unknown function (DUF5052)
DEMGKBKK_01789 9.4e-68 XK27_00160 S Domain of unknown function (DUF5052)
DEMGKBKK_01790 5.6e-26 adk 2.7.4.3 F topology modulation protein
DEMGKBKK_01791 5.3e-67
DEMGKBKK_01792 1.7e-204 xerS L Belongs to the 'phage' integrase family
DEMGKBKK_01793 1.9e-158 degV S EDD domain protein, DegV family
DEMGKBKK_01794 3.8e-64
DEMGKBKK_01795 0.0 FbpA K Fibronectin-binding protein
DEMGKBKK_01796 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
DEMGKBKK_01797 1.9e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DEMGKBKK_01798 1.3e-152 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DEMGKBKK_01799 2.8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DEMGKBKK_01800 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DEMGKBKK_01801 1.2e-230 cpdA S Calcineurin-like phosphoesterase
DEMGKBKK_01802 6.9e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DEMGKBKK_01803 5.2e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DEMGKBKK_01804 2.3e-104 ypsA S Belongs to the UPF0398 family
DEMGKBKK_01805 1.3e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DEMGKBKK_01806 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
DEMGKBKK_01807 2.5e-112 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DEMGKBKK_01808 7.4e-115 dnaD L DnaD domain protein
DEMGKBKK_01809 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
DEMGKBKK_01810 1.6e-88 ypmB S Protein conserved in bacteria
DEMGKBKK_01811 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DEMGKBKK_01812 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DEMGKBKK_01813 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DEMGKBKK_01814 9.9e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
DEMGKBKK_01815 2.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DEMGKBKK_01816 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
DEMGKBKK_01817 2.6e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DEMGKBKK_01818 1.8e-259 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
DEMGKBKK_01819 4.4e-175
DEMGKBKK_01820 4.3e-138
DEMGKBKK_01821 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DEMGKBKK_01822 7.8e-28
DEMGKBKK_01823 1.3e-246 rarA L recombination factor protein RarA
DEMGKBKK_01824 1.2e-112
DEMGKBKK_01825 3.8e-140
DEMGKBKK_01826 3.8e-143
DEMGKBKK_01827 3.4e-121 skfE V ATPases associated with a variety of cellular activities
DEMGKBKK_01828 1.5e-59 yvoA_1 K Transcriptional regulator, GntR family
DEMGKBKK_01829 1.8e-242 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DEMGKBKK_01830 1e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DEMGKBKK_01831 1.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
DEMGKBKK_01832 2.3e-67 mutT 3.6.1.55 F NUDIX domain
DEMGKBKK_01833 1.4e-124 S Peptidase family M23
DEMGKBKK_01834 1.2e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DEMGKBKK_01835 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DEMGKBKK_01836 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DEMGKBKK_01837 3.9e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DEMGKBKK_01838 1.7e-134 recO L Involved in DNA repair and RecF pathway recombination
DEMGKBKK_01839 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
DEMGKBKK_01840 1.6e-123 gntR1 K UTRA
DEMGKBKK_01841 6e-213
DEMGKBKK_01844 1.4e-87
DEMGKBKK_01846 5.4e-267 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
DEMGKBKK_01847 3.2e-211 msmX P Belongs to the ABC transporter superfamily
DEMGKBKK_01848 9.5e-255 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
DEMGKBKK_01849 3.3e-155 msmG G Binding-protein-dependent transport system inner membrane component
DEMGKBKK_01850 4.5e-163 msmF P ABC-type sugar transport systems, permease components
DEMGKBKK_01851 7.3e-239 msmE G Bacterial extracellular solute-binding protein
DEMGKBKK_01852 6.2e-182 msmR K helix_turn _helix lactose operon repressor
DEMGKBKK_01853 3.3e-129 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
DEMGKBKK_01854 7.6e-115 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
DEMGKBKK_01855 7.7e-103 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
DEMGKBKK_01856 2.6e-111 G Phosphoglycerate mutase family
DEMGKBKK_01857 1.3e-196 D nuclear chromosome segregation
DEMGKBKK_01858 7.3e-52 M LysM domain protein
DEMGKBKK_01859 5.6e-13
DEMGKBKK_01860 6.9e-156 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
DEMGKBKK_01861 7.8e-67
DEMGKBKK_01862 7.1e-32
DEMGKBKK_01863 4.1e-71 S Iron-sulphur cluster biosynthesis
DEMGKBKK_01864 2.2e-28 K Transcriptional regulator
DEMGKBKK_01865 1.2e-227 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
DEMGKBKK_01866 4.2e-127 XK27_08435 K UTRA
DEMGKBKK_01868 1e-215 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEMGKBKK_01869 2.3e-155 CE10 I Belongs to the type-B carboxylesterase lipase family
DEMGKBKK_01870 1.5e-232 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
DEMGKBKK_01871 1.3e-121 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DEMGKBKK_01872 1.5e-23 pts15B 2.7.1.196, 2.7.1.205 G PTS family porter, IIB component
DEMGKBKK_01873 8.5e-25 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
DEMGKBKK_01874 1.3e-19 S Domain of unknown function (DUF3284)
DEMGKBKK_01875 7.1e-132 K Psort location Cytoplasmic, score 8.87
DEMGKBKK_01876 4.4e-86 C FAD binding domain
DEMGKBKK_01877 3.5e-25 C FAD binding domain
DEMGKBKK_01878 1.2e-47 C FAD binding domain
DEMGKBKK_01880 1.7e-139 S Uncharacterized protein conserved in bacteria (DUF2263)
DEMGKBKK_01881 5.1e-60
DEMGKBKK_01882 0.0 lhr L DEAD DEAH box helicase
DEMGKBKK_01883 1.2e-249 P P-loop Domain of unknown function (DUF2791)
DEMGKBKK_01884 2.8e-260 S TerB-C domain
DEMGKBKK_01885 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
DEMGKBKK_01886 2.8e-30 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
DEMGKBKK_01887 2.9e-37
DEMGKBKK_01888 3.1e-133 4.1.1.44 S Carboxymuconolactone decarboxylase family
DEMGKBKK_01889 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DEMGKBKK_01890 5.6e-36 S LPXTG cell wall anchor motif
DEMGKBKK_01891 6.8e-46 UW LPXTG-motif cell wall anchor domain protein
DEMGKBKK_01892 2.8e-79
DEMGKBKK_01893 1.8e-38
DEMGKBKK_01894 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DEMGKBKK_01895 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DEMGKBKK_01896 1.1e-237 cycA E Amino acid permease
DEMGKBKK_01897 2.4e-84 maa S transferase hexapeptide repeat
DEMGKBKK_01898 1.5e-127 K Transcriptional regulator
DEMGKBKK_01899 3.2e-62 manO S Domain of unknown function (DUF956)
DEMGKBKK_01900 1.6e-171 manN G system, mannose fructose sorbose family IID component
DEMGKBKK_01901 1.5e-133 manY G PTS system
DEMGKBKK_01902 4.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)