ORF_ID e_value Gene_name EC_number CAZy COGs Description
NPHCGAGA_00001 8.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPHCGAGA_00002 2.7e-91 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPHCGAGA_00003 1.2e-174 phoH T phosphate starvation-inducible protein PhoH
NPHCGAGA_00004 2.7e-68 yqeY S YqeY-like protein
NPHCGAGA_00005 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NPHCGAGA_00006 9.8e-152 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPHCGAGA_00007 8e-106 S Peptidase family M23
NPHCGAGA_00008 9.3e-161 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPHCGAGA_00009 1.4e-105
NPHCGAGA_00010 1.1e-37 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPHCGAGA_00011 9.7e-82 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPHCGAGA_00012 1.2e-23 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NPHCGAGA_00013 4.7e-122 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NPHCGAGA_00014 1.3e-244 thrC 4.2.3.1 E Threonine synthase
NPHCGAGA_00015 4.8e-115 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPHCGAGA_00016 5.1e-84 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPHCGAGA_00017 1.5e-26 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPHCGAGA_00018 1.1e-102 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NPHCGAGA_00019 2.9e-28
NPHCGAGA_00020 5.6e-42
NPHCGAGA_00021 3.5e-106 K LysR substrate binding domain
NPHCGAGA_00022 1.2e-18
NPHCGAGA_00023 5.3e-212 S Sterol carrier protein domain
NPHCGAGA_00024 6.4e-96 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NPHCGAGA_00025 6.7e-125 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NPHCGAGA_00026 1.1e-31 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NPHCGAGA_00027 1.4e-187 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPHCGAGA_00028 8.4e-166 arcA 3.5.3.6 E Arginine
NPHCGAGA_00029 9.2e-26 arcA 3.5.3.6 E Arginine
NPHCGAGA_00030 1.3e-154 lysR5 K LysR substrate binding domain
NPHCGAGA_00031 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NPHCGAGA_00032 7.6e-83 3.4.21.96 S SLAP domain
NPHCGAGA_00033 1.6e-248 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPHCGAGA_00034 1.1e-147 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NPHCGAGA_00035 2.6e-30 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPHCGAGA_00036 3e-122 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPHCGAGA_00037 7e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPHCGAGA_00038 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NPHCGAGA_00039 1.9e-116 srtA 3.4.22.70 M sortase family
NPHCGAGA_00040 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPHCGAGA_00041 2.1e-20
NPHCGAGA_00042 6e-200 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPHCGAGA_00043 0.0 dnaK O Heat shock 70 kDa protein
NPHCGAGA_00044 1.3e-81 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPHCGAGA_00045 1.2e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPHCGAGA_00046 1.4e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NPHCGAGA_00047 2.8e-165 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPHCGAGA_00048 1.1e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPHCGAGA_00049 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPHCGAGA_00050 1.2e-46 rplGA J ribosomal protein
NPHCGAGA_00051 1.2e-46 ylxR K Protein of unknown function (DUF448)
NPHCGAGA_00052 2.9e-194 nusA K Participates in both transcription termination and antitermination
NPHCGAGA_00053 6.7e-81 rimP J Required for maturation of 30S ribosomal subunits
NPHCGAGA_00054 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPHCGAGA_00055 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPHCGAGA_00056 2.6e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NPHCGAGA_00057 5.1e-145 cdsA 2.7.7.41 I Belongs to the CDS family
NPHCGAGA_00058 1.6e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPHCGAGA_00059 7.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPHCGAGA_00060 7e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NPHCGAGA_00061 8.3e-185 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPHCGAGA_00062 1.4e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
NPHCGAGA_00063 4.2e-197 yabB 2.1.1.223 L Methyltransferase small domain
NPHCGAGA_00064 5.1e-113 plsC 2.3.1.51 I Acyltransferase
NPHCGAGA_00065 1.5e-227 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NPHCGAGA_00066 0.0 pepO 3.4.24.71 O Peptidase family M13
NPHCGAGA_00067 2.1e-300 mdlB V ABC transporter
NPHCGAGA_00068 1.6e-297 mdlA V ABC transporter
NPHCGAGA_00069 4.2e-30 yneF S Uncharacterised protein family (UPF0154)
NPHCGAGA_00070 7.4e-37 ynzC S UPF0291 protein
NPHCGAGA_00071 2.8e-111 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPHCGAGA_00072 3.4e-146 E GDSL-like Lipase/Acylhydrolase family
NPHCGAGA_00073 6.4e-99 ung2 3.2.2.27 L Uracil-DNA glycosylase
NPHCGAGA_00074 5.5e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPHCGAGA_00075 1.7e-136 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPHCGAGA_00076 1.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPHCGAGA_00077 4.5e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NPHCGAGA_00078 3.8e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPHCGAGA_00079 3.2e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPHCGAGA_00080 1.5e-256 yfnA E amino acid
NPHCGAGA_00081 4e-43
NPHCGAGA_00082 1.7e-289 pipD E Dipeptidase
NPHCGAGA_00083 1.3e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPHCGAGA_00084 0.0 smc D Required for chromosome condensation and partitioning
NPHCGAGA_00085 1.3e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPHCGAGA_00086 0.0 oppA E ABC transporter substrate-binding protein
NPHCGAGA_00087 0.0 oppA E ABC transporter substrate-binding protein
NPHCGAGA_00088 3.3e-148 oppC P Binding-protein-dependent transport system inner membrane component
NPHCGAGA_00089 2.5e-175 oppB P ABC transporter permease
NPHCGAGA_00090 5.3e-181 oppF P Belongs to the ABC transporter superfamily
NPHCGAGA_00091 2e-194 oppD P Belongs to the ABC transporter superfamily
NPHCGAGA_00092 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPHCGAGA_00093 2.1e-180 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPHCGAGA_00094 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPHCGAGA_00095 9.9e-305 yloV S DAK2 domain fusion protein YloV
NPHCGAGA_00096 6.8e-57 asp S Asp23 family, cell envelope-related function
NPHCGAGA_00097 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NPHCGAGA_00098 1.1e-47
NPHCGAGA_00099 6.4e-125 thiN 2.7.6.2 H thiamine pyrophosphokinase
NPHCGAGA_00100 2.6e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NPHCGAGA_00101 9.7e-166 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPHCGAGA_00102 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NPHCGAGA_00103 1e-145 stp 3.1.3.16 T phosphatase
NPHCGAGA_00104 5.4e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPHCGAGA_00105 6.7e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPHCGAGA_00106 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPHCGAGA_00107 9.4e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPHCGAGA_00108 1.8e-110 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NPHCGAGA_00109 1e-78 6.3.3.2 S ASCH
NPHCGAGA_00110 1.1e-306 recN L May be involved in recombinational repair of damaged DNA
NPHCGAGA_00111 8.1e-151 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NPHCGAGA_00112 3.6e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPHCGAGA_00113 2.1e-22 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPHCGAGA_00114 3.4e-194 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPHCGAGA_00115 6.9e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPHCGAGA_00116 1.4e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPHCGAGA_00117 2.4e-69 yqhY S Asp23 family, cell envelope-related function
NPHCGAGA_00118 1.4e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPHCGAGA_00119 4.1e-198 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPHCGAGA_00120 1e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NPHCGAGA_00121 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NPHCGAGA_00122 7.7e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
NPHCGAGA_00123 1.5e-197 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NPHCGAGA_00124 3.4e-123 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NPHCGAGA_00125 2.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NPHCGAGA_00126 0.0 S Predicted membrane protein (DUF2207)
NPHCGAGA_00127 3.7e-200 M Glycosyl hydrolases family 25
NPHCGAGA_00129 6.1e-176 I Carboxylesterase family
NPHCGAGA_00130 2.3e-65 arsC 1.20.4.1 P Belongs to the ArsC family
NPHCGAGA_00131 4e-27
NPHCGAGA_00132 6.9e-62 S Bacterial PH domain
NPHCGAGA_00133 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPHCGAGA_00134 1.4e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NPHCGAGA_00135 1.1e-46
NPHCGAGA_00136 1.3e-142 glcU U sugar transport
NPHCGAGA_00138 2.6e-38
NPHCGAGA_00139 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NPHCGAGA_00140 5.1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPHCGAGA_00141 2.3e-240 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPHCGAGA_00142 1.5e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NPHCGAGA_00143 2.3e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPHCGAGA_00144 8.5e-165 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPHCGAGA_00145 4e-122 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPHCGAGA_00146 8.2e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPHCGAGA_00147 7e-11 S RelB antitoxin
NPHCGAGA_00148 1.8e-84 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NPHCGAGA_00149 1.2e-178 tcsA S ABC transporter substrate-binding protein PnrA-like
NPHCGAGA_00150 2.3e-247 xylG 3.6.3.17 S ABC transporter
NPHCGAGA_00151 1.5e-166 yufP S Belongs to the binding-protein-dependent transport system permease family
NPHCGAGA_00152 1.7e-160 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPHCGAGA_00153 0.0 3.6.3.8 P P-type ATPase
NPHCGAGA_00154 7.1e-207 G Major Facilitator Superfamily
NPHCGAGA_00155 1.8e-47
NPHCGAGA_00156 1.3e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NPHCGAGA_00157 1.1e-145 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NPHCGAGA_00158 3.4e-52 S Iron-sulfur cluster assembly protein
NPHCGAGA_00159 4.8e-48 M NlpC/P60 family
NPHCGAGA_00160 2.2e-46 M NlpC/P60 family
NPHCGAGA_00161 9.1e-33 M NlpC/P60 family
NPHCGAGA_00162 7.4e-127 G Peptidase_C39 like family
NPHCGAGA_00163 3e-26
NPHCGAGA_00164 2.2e-122 F DNA/RNA non-specific endonuclease
NPHCGAGA_00165 2.1e-56 L nuclease
NPHCGAGA_00166 1.7e-19 S Metal binding domain of Ada
NPHCGAGA_00168 8.3e-31
NPHCGAGA_00170 8.5e-218 S SLAP domain
NPHCGAGA_00172 3.6e-142 mrr L restriction endonuclease
NPHCGAGA_00173 3.8e-220 S response to antibiotic
NPHCGAGA_00174 5e-90
NPHCGAGA_00177 1.8e-193 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NPHCGAGA_00178 9.7e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPHCGAGA_00179 1.3e-271 yjeM E Amino Acid
NPHCGAGA_00180 1.1e-201
NPHCGAGA_00181 6e-83
NPHCGAGA_00182 1.3e-125 dkgA 1.1.1.346 S L-ascorbic acid biosynthetic process
NPHCGAGA_00183 1.6e-70 O OsmC-like protein
NPHCGAGA_00184 4.7e-208 EGP Major facilitator Superfamily
NPHCGAGA_00185 7.5e-57 sptS 2.7.13.3 T Histidine kinase
NPHCGAGA_00186 3.5e-99 sptS 2.7.13.3 T Histidine kinase
NPHCGAGA_00187 8.2e-51 2.7.6.5 T Region found in RelA / SpoT proteins
NPHCGAGA_00188 2.5e-23 2.7.6.5 T Region found in RelA / SpoT proteins
NPHCGAGA_00189 3.2e-245 S SLAP domain
NPHCGAGA_00190 3.8e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NPHCGAGA_00191 5.9e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NPHCGAGA_00192 2.6e-219 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPHCGAGA_00193 3.3e-186 lacR K Transcriptional regulator
NPHCGAGA_00194 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NPHCGAGA_00195 2.3e-167 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NPHCGAGA_00196 7.5e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPHCGAGA_00197 3.6e-79 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_00198 4.4e-146
NPHCGAGA_00199 2.7e-163
NPHCGAGA_00200 1.9e-134
NPHCGAGA_00201 1.2e-260 glnA 6.3.1.2 E glutamine synthetase
NPHCGAGA_00202 3.3e-169 ynbB 4.4.1.1 P aluminum resistance
NPHCGAGA_00203 1e-33 ynbB 4.4.1.1 P aluminum resistance
NPHCGAGA_00204 6.7e-170 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPHCGAGA_00205 1.5e-68 yqhL P Rhodanese-like protein
NPHCGAGA_00206 5.6e-33 yqgQ S Bacterial protein of unknown function (DUF910)
NPHCGAGA_00207 2.7e-115 gluP 3.4.21.105 S Rhomboid family
NPHCGAGA_00208 2.5e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPHCGAGA_00209 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPHCGAGA_00210 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NPHCGAGA_00211 0.0 S membrane
NPHCGAGA_00212 3.1e-167 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NPHCGAGA_00213 5.3e-27 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_00214 1.7e-54 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_00215 1.5e-99 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_00216 5.3e-38 K Helix-turn-helix domain
NPHCGAGA_00217 4.9e-22 S Phage derived protein Gp49-like (DUF891)
NPHCGAGA_00218 3.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
NPHCGAGA_00219 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPHCGAGA_00220 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPHCGAGA_00221 1.5e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPHCGAGA_00222 1.5e-61 yodB K Transcriptional regulator, HxlR family
NPHCGAGA_00223 1.1e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPHCGAGA_00224 2.4e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NPHCGAGA_00225 4.1e-154 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPHCGAGA_00226 1.3e-84 S Aminoacyl-tRNA editing domain
NPHCGAGA_00227 4.3e-278 arlS 2.7.13.3 T Histidine kinase
NPHCGAGA_00228 1e-125 K response regulator
NPHCGAGA_00229 1.5e-95 yceD S Uncharacterized ACR, COG1399
NPHCGAGA_00230 4.3e-214 ylbM S Belongs to the UPF0348 family
NPHCGAGA_00231 6.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPHCGAGA_00232 9.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NPHCGAGA_00233 4.1e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPHCGAGA_00234 1.5e-211 yqeH S Ribosome biogenesis GTPase YqeH
NPHCGAGA_00235 3.8e-93 yqeG S HAD phosphatase, family IIIA
NPHCGAGA_00236 5.1e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPHCGAGA_00237 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NPHCGAGA_00238 4.8e-55 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPHCGAGA_00239 5.5e-239 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
NPHCGAGA_00240 9.3e-30 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
NPHCGAGA_00241 4.9e-101 S Domain of unknown function (DUF389)
NPHCGAGA_00242 1.8e-24 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPHCGAGA_00243 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPHCGAGA_00244 2.9e-165 dnaI L Primosomal protein DnaI
NPHCGAGA_00245 8.9e-248 dnaB L Replication initiation and membrane attachment
NPHCGAGA_00246 1.6e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPHCGAGA_00247 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPHCGAGA_00248 1.2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPHCGAGA_00249 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPHCGAGA_00251 8.1e-14
NPHCGAGA_00252 4.1e-16
NPHCGAGA_00253 8.5e-130 qmcA O prohibitin homologues
NPHCGAGA_00254 1.7e-40 L RelB antitoxin
NPHCGAGA_00255 6.1e-103 M Peptidase family M1 domain
NPHCGAGA_00256 4.2e-68 M Peptidase family M1 domain
NPHCGAGA_00257 9.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NPHCGAGA_00258 4e-60 S Psort location Cytoplasmic, score
NPHCGAGA_00261 3.4e-260
NPHCGAGA_00262 3.3e-123 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPHCGAGA_00263 7.3e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPHCGAGA_00264 2.6e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPHCGAGA_00265 2.9e-213 ecsB U ABC transporter
NPHCGAGA_00266 1.1e-135 ecsA V ABC transporter, ATP-binding protein
NPHCGAGA_00267 1.4e-53 higA K Helix-turn-helix XRE-family like proteins
NPHCGAGA_00268 2.3e-34 S Plasmid maintenance system killer
NPHCGAGA_00269 3.1e-80 hit FG Scavenger mRNA decapping enzyme C-term binding
NPHCGAGA_00270 3.3e-26
NPHCGAGA_00271 3.5e-155 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPHCGAGA_00272 1.3e-187 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPHCGAGA_00273 0.0 L AAA domain
NPHCGAGA_00274 2.9e-229 yhaO L Ser Thr phosphatase family protein
NPHCGAGA_00275 9.4e-56 yheA S Belongs to the UPF0342 family
NPHCGAGA_00276 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPHCGAGA_00277 8.2e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPHCGAGA_00278 2.5e-09 5.3.3.2 C FMN-dependent dehydrogenase
NPHCGAGA_00279 3.2e-84 mgtC S MgtC family
NPHCGAGA_00280 7.3e-138 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NPHCGAGA_00281 7.8e-252 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHCGAGA_00282 2.4e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPHCGAGA_00283 9.8e-55
NPHCGAGA_00284 1.9e-147 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NPHCGAGA_00285 1.3e-213 L transposase, IS605 OrfB family
NPHCGAGA_00286 2.6e-42
NPHCGAGA_00287 1.3e-48
NPHCGAGA_00288 1.6e-149 yitS S EDD domain protein, DegV family
NPHCGAGA_00289 2.1e-82 racA K Domain of unknown function (DUF1836)
NPHCGAGA_00290 4.8e-17 yniG EGP Major facilitator Superfamily
NPHCGAGA_00291 1.6e-89 S GyrI-like small molecule binding domain
NPHCGAGA_00292 8.2e-27
NPHCGAGA_00293 3.2e-106
NPHCGAGA_00294 2.9e-114 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NPHCGAGA_00295 4.4e-101
NPHCGAGA_00296 1.1e-110 M LysM domain
NPHCGAGA_00297 2.7e-143 K LytTr DNA-binding domain
NPHCGAGA_00298 4.7e-95 2.7.13.3 T GHKL domain
NPHCGAGA_00299 1.1e-30
NPHCGAGA_00300 8.1e-39
NPHCGAGA_00301 1.9e-46 3.6.1.55 L NUDIX domain
NPHCGAGA_00302 1e-170 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NPHCGAGA_00303 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NPHCGAGA_00304 8.7e-11 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPHCGAGA_00305 4.5e-106 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPHCGAGA_00306 6.2e-105 padC Q Phenolic acid decarboxylase
NPHCGAGA_00307 3e-90 padR K Virulence activator alpha C-term
NPHCGAGA_00308 3.1e-108 M ErfK YbiS YcfS YnhG
NPHCGAGA_00309 3.1e-153 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPHCGAGA_00310 6.9e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPHCGAGA_00312 4.4e-49 pspC KT PspC domain
NPHCGAGA_00313 3.6e-96 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
NPHCGAGA_00314 2.6e-90 psd 4.1.1.65 I Belongs to the phosphatidylserine decarboxylase family
NPHCGAGA_00315 1.9e-37 S Enterocin A Immunity
NPHCGAGA_00316 3.5e-138 yxeH S hydrolase
NPHCGAGA_00317 2.5e-31 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPHCGAGA_00318 5.5e-52 frnE Q DSBA-like thioredoxin domain
NPHCGAGA_00319 7.3e-16 frnE Q DSBA-like thioredoxin domain
NPHCGAGA_00320 3.5e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPHCGAGA_00321 2e-115 M1-798 K Rhodanese Homology Domain
NPHCGAGA_00322 2e-58 CO Thioredoxin
NPHCGAGA_00323 2.1e-20
NPHCGAGA_00325 9.4e-52 infB UW LPXTG-motif cell wall anchor domain protein
NPHCGAGA_00326 5.1e-68 infB UW LPXTG-motif cell wall anchor domain protein
NPHCGAGA_00327 7.6e-23 dhaL 2.7.1.121 S Dak2
NPHCGAGA_00328 2.2e-154 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NPHCGAGA_00329 7.2e-09 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NPHCGAGA_00330 1e-293 ytgP S Polysaccharide biosynthesis protein
NPHCGAGA_00331 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPHCGAGA_00332 5.6e-118 3.6.1.27 I Acid phosphatase homologues
NPHCGAGA_00333 4.8e-52 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPHCGAGA_00334 1.4e-64 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPHCGAGA_00335 9.9e-12 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPHCGAGA_00336 1.6e-261 qacA EGP Major facilitator Superfamily
NPHCGAGA_00337 4.3e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPHCGAGA_00340 8e-168 psaA P Belongs to the bacterial solute-binding protein 9 family
NPHCGAGA_00343 3.5e-113 pbpX2 V Beta-lactamase
NPHCGAGA_00344 6.7e-104 3.2.2.20 K acetyltransferase
NPHCGAGA_00345 5.3e-95
NPHCGAGA_00346 3.7e-32
NPHCGAGA_00347 1.7e-267 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
NPHCGAGA_00348 3.2e-133 glvR K Helix-turn-helix domain, rpiR family
NPHCGAGA_00349 1.6e-185 ansA 3.5.1.1 EJ L-asparaginase, type I
NPHCGAGA_00350 5.4e-15
NPHCGAGA_00351 4.8e-125
NPHCGAGA_00352 3e-237 S response to antibiotic
NPHCGAGA_00353 1.1e-126 pgm3 G Phosphoglycerate mutase family
NPHCGAGA_00354 1.1e-119 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NPHCGAGA_00355 0.0 helD 3.6.4.12 L DNA helicase
NPHCGAGA_00356 1.1e-107 glnP P ABC transporter permease
NPHCGAGA_00357 1.5e-109 glnQ 3.6.3.21 E ABC transporter
NPHCGAGA_00358 3.4e-149 aatB ET ABC transporter substrate-binding protein
NPHCGAGA_00359 3.2e-77 yjcF S Acetyltransferase (GNAT) domain
NPHCGAGA_00360 1.6e-102 E GDSL-like Lipase/Acylhydrolase
NPHCGAGA_00361 3.9e-170 coaA 2.7.1.33 F Pantothenic acid kinase
NPHCGAGA_00362 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPHCGAGA_00363 4.1e-67 yybA 2.3.1.57 K Transcriptional regulator
NPHCGAGA_00364 8.4e-85 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NPHCGAGA_00365 2.3e-65 S Peptidase propeptide and YPEB domain
NPHCGAGA_00366 1.3e-95 F Nucleoside 2-deoxyribosyltransferase
NPHCGAGA_00367 9.5e-186 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NPHCGAGA_00368 7.9e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NPHCGAGA_00369 6.7e-274 V ABC transporter transmembrane region
NPHCGAGA_00370 1.2e-108 S PAS domain
NPHCGAGA_00371 1.1e-10
NPHCGAGA_00372 4.9e-139 pnuC H nicotinamide mononucleotide transporter
NPHCGAGA_00373 2.7e-17 S Protein of unknown function (DUF3290)
NPHCGAGA_00374 6.8e-41 S Protein of unknown function (DUF3290)
NPHCGAGA_00375 1.6e-106 yviA S Protein of unknown function (DUF421)
NPHCGAGA_00376 6.9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NPHCGAGA_00377 8.3e-163 dnaQ 2.7.7.7 L EXOIII
NPHCGAGA_00378 4.1e-153 endA F DNA RNA non-specific endonuclease
NPHCGAGA_00379 5.5e-280 pipD E Dipeptidase
NPHCGAGA_00380 1.3e-201 malK P ATPases associated with a variety of cellular activities
NPHCGAGA_00381 1.9e-158 gtsB P ABC-type sugar transport systems, permease components
NPHCGAGA_00382 2.3e-145 gtsC P Binding-protein-dependent transport system inner membrane component
NPHCGAGA_00383 1.1e-253 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
NPHCGAGA_00384 1.4e-234 G Bacterial extracellular solute-binding protein
NPHCGAGA_00385 1.1e-156 corA P CorA-like Mg2+ transporter protein
NPHCGAGA_00386 1.4e-154 3.5.2.6 V Beta-lactamase enzyme family
NPHCGAGA_00387 6.2e-97 yobS K Bacterial regulatory proteins, tetR family
NPHCGAGA_00388 0.0 ydgH S MMPL family
NPHCGAGA_00389 2.4e-152
NPHCGAGA_00390 1.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NPHCGAGA_00391 4.3e-124 hipB K Helix-turn-helix
NPHCGAGA_00392 7.2e-152 I alpha/beta hydrolase fold
NPHCGAGA_00393 1.3e-108 yjbF S SNARE associated Golgi protein
NPHCGAGA_00394 9.2e-98 J Acetyltransferase (GNAT) domain
NPHCGAGA_00395 5.3e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPHCGAGA_00399 1.5e-155 M Glycosyl hydrolases family 25
NPHCGAGA_00400 3.6e-22
NPHCGAGA_00401 4.6e-16
NPHCGAGA_00402 6e-17
NPHCGAGA_00403 4.6e-20 S Phage uncharacterised protein (Phage_XkdX)
NPHCGAGA_00404 1.3e-57
NPHCGAGA_00409 3.7e-137
NPHCGAGA_00410 3.8e-36
NPHCGAGA_00411 2.9e-10
NPHCGAGA_00412 1.2e-123 Z012_12235 S Baseplate J-like protein
NPHCGAGA_00413 2.1e-32
NPHCGAGA_00414 1.5e-44
NPHCGAGA_00415 2.8e-111
NPHCGAGA_00416 2.3e-37
NPHCGAGA_00417 8.7e-54 M LysM domain
NPHCGAGA_00418 9e-206 3.4.14.13 M Phage tail tape measure protein TP901
NPHCGAGA_00420 5.3e-11
NPHCGAGA_00421 1.4e-29
NPHCGAGA_00422 6.9e-104 Z012_02110 S Protein of unknown function (DUF3383)
NPHCGAGA_00423 1.7e-35
NPHCGAGA_00424 1.5e-28
NPHCGAGA_00425 9e-31
NPHCGAGA_00426 1.4e-20 S Protein of unknown function (DUF4054)
NPHCGAGA_00427 5e-91 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
NPHCGAGA_00428 5.7e-34
NPHCGAGA_00429 5.7e-52 S Uncharacterized protein conserved in bacteria (DUF2213)
NPHCGAGA_00430 2.1e-10 S Lysin motif
NPHCGAGA_00431 8.8e-49 S Phage Mu protein F like protein
NPHCGAGA_00432 1e-137 S Protein of unknown function (DUF1073)
NPHCGAGA_00433 8.7e-204 S Terminase-like family
NPHCGAGA_00434 2.7e-20 ps333 L Terminase small subunit
NPHCGAGA_00438 2.9e-07
NPHCGAGA_00439 2e-41 S VRR_NUC
NPHCGAGA_00456 1.8e-62 L DnaD domain protein
NPHCGAGA_00457 4.7e-47 S ERF superfamily
NPHCGAGA_00458 2.1e-36 S Protein of unknown function (DUF1351)
NPHCGAGA_00461 2.7e-17
NPHCGAGA_00466 2.2e-81 ps308 K AntA/AntB antirepressor
NPHCGAGA_00468 2.2e-25 K Cro/C1-type HTH DNA-binding domain
NPHCGAGA_00469 1.2e-10 E Zn peptidase
NPHCGAGA_00475 1.7e-59 L Belongs to the 'phage' integrase family
NPHCGAGA_00476 1.2e-168 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NPHCGAGA_00478 6.5e-53
NPHCGAGA_00479 2.2e-237 I Protein of unknown function (DUF2974)
NPHCGAGA_00480 3.7e-120 yhiD S MgtC family
NPHCGAGA_00482 1.6e-30
NPHCGAGA_00485 1.5e-29 WQ51_00220 K Helix-turn-helix XRE-family like proteins
NPHCGAGA_00486 6.6e-73 ybbL S ABC transporter, ATP-binding protein
NPHCGAGA_00487 4.3e-130 ybbM S Uncharacterised protein family (UPF0014)
NPHCGAGA_00488 4.2e-53 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NPHCGAGA_00489 4.6e-231 S LPXTG cell wall anchor motif
NPHCGAGA_00490 2.3e-147 S Putative ABC-transporter type IV
NPHCGAGA_00491 2.5e-98 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
NPHCGAGA_00492 6.5e-85 S ECF transporter, substrate-specific component
NPHCGAGA_00493 3e-58 S Domain of unknown function (DUF4430)
NPHCGAGA_00494 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
NPHCGAGA_00495 1.2e-175 K AI-2E family transporter
NPHCGAGA_00496 4.4e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
NPHCGAGA_00497 1.3e-11
NPHCGAGA_00498 6.4e-44
NPHCGAGA_00499 4.8e-129 XK27_08845 S ABC transporter, ATP-binding protein
NPHCGAGA_00500 6.9e-119 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NPHCGAGA_00501 1.3e-171 ABC-SBP S ABC transporter
NPHCGAGA_00502 1.7e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPHCGAGA_00503 9.7e-163 yvgN C Aldo keto reductase
NPHCGAGA_00505 0.0 tetP J elongation factor G
NPHCGAGA_00506 1.6e-143 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NPHCGAGA_00507 4e-28
NPHCGAGA_00508 1.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHCGAGA_00509 1.2e-168 yniA G Phosphotransferase enzyme family
NPHCGAGA_00510 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
NPHCGAGA_00511 1.1e-262 E amino acid
NPHCGAGA_00512 0.0 L Helicase C-terminal domain protein
NPHCGAGA_00513 1.6e-193 pbpX1 V Beta-lactamase
NPHCGAGA_00514 6.7e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPHCGAGA_00515 2e-302
NPHCGAGA_00516 4.7e-81
NPHCGAGA_00517 2.4e-109 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPHCGAGA_00518 1.8e-65 S ASCH domain
NPHCGAGA_00519 1.6e-42 4.4.1.5 E lactoylglutathione lyase activity
NPHCGAGA_00520 3e-19
NPHCGAGA_00521 3.4e-115 metQ2 P Belongs to the nlpA lipoprotein family
NPHCGAGA_00522 8e-31
NPHCGAGA_00523 6e-44 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
NPHCGAGA_00524 9.9e-74 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
NPHCGAGA_00525 2.1e-151
NPHCGAGA_00526 1.8e-236 S Protein of unknown function DUF262
NPHCGAGA_00527 2.2e-105 S Putative inner membrane protein (DUF1819)
NPHCGAGA_00528 2.3e-110 S Domain of unknown function (DUF1788)
NPHCGAGA_00529 6.6e-216 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
NPHCGAGA_00530 4.8e-107 V Eco57I restriction-modification methylase
NPHCGAGA_00531 2.5e-208 2.1.1.72 V Eco57I restriction-modification methylase
NPHCGAGA_00532 0.0 S PglZ domain
NPHCGAGA_00533 0.0
NPHCGAGA_00534 7.9e-24 L PFAM transposase, IS4 family protein
NPHCGAGA_00535 1.4e-101 L PFAM transposase, IS4 family protein
NPHCGAGA_00536 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPHCGAGA_00537 0.0 pepO 3.4.24.71 O Peptidase family M13
NPHCGAGA_00538 1.9e-09 pepO 3.4.24.71 O Peptidase family M13
NPHCGAGA_00539 3.3e-59 pdxH S Pyridoxamine 5'-phosphate oxidase
NPHCGAGA_00540 3.4e-241 N Uncharacterized conserved protein (DUF2075)
NPHCGAGA_00541 6.7e-11 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NPHCGAGA_00542 2.9e-35
NPHCGAGA_00543 2.8e-199 S C4-dicarboxylate anaerobic carrier
NPHCGAGA_00544 3.5e-12 mta K helix_turn_helix, mercury resistance
NPHCGAGA_00545 2e-61 mta K helix_turn_helix, mercury resistance
NPHCGAGA_00546 6.5e-16 mta K helix_turn_helix, mercury resistance
NPHCGAGA_00547 9.8e-94 yyaR K Acetyltransferase (GNAT) domain
NPHCGAGA_00548 0.0 uvrA3 L excinuclease ABC, A subunit
NPHCGAGA_00551 1.9e-59 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
NPHCGAGA_00552 7.6e-223 mepA V MATE efflux family protein
NPHCGAGA_00553 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
NPHCGAGA_00554 3.9e-34 copZ C Heavy-metal-associated domain
NPHCGAGA_00555 9.8e-72 dps P Belongs to the Dps family
NPHCGAGA_00556 3.2e-59 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NPHCGAGA_00557 1.9e-33 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NPHCGAGA_00558 1.4e-87 K Acetyltransferase (GNAT) family
NPHCGAGA_00559 8.9e-140 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NPHCGAGA_00560 8.8e-229 yrvN L AAA C-terminal domain
NPHCGAGA_00561 2.4e-31
NPHCGAGA_00562 1.2e-70 fabK 1.3.1.9 S Nitronate monooxygenase
NPHCGAGA_00563 4.5e-84 kptA H Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NPHCGAGA_00564 9.4e-65 S Abi-like protein
NPHCGAGA_00566 2.9e-72 4.1.1.45 S Amidohydrolase
NPHCGAGA_00567 2.2e-67 4.1.1.45 S Amidohydrolase
NPHCGAGA_00568 4.8e-76 lacA 2.3.1.79 S Maltose acetyltransferase
NPHCGAGA_00569 2.2e-108 G Antibiotic biosynthesis monooxygenase
NPHCGAGA_00570 2.8e-27 S Uncharacterized protein conserved in bacteria (DUF2255)
NPHCGAGA_00571 1.3e-69 adhR K helix_turn_helix, mercury resistance
NPHCGAGA_00572 3.9e-111 papP P ABC transporter, permease protein
NPHCGAGA_00573 3.1e-87 P ABC transporter permease
NPHCGAGA_00574 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPHCGAGA_00575 2.2e-159 cjaA ET ABC transporter substrate-binding protein
NPHCGAGA_00579 4.2e-55 doc S Fic/DOC family
NPHCGAGA_00580 1.3e-235 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPHCGAGA_00581 1.4e-49 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NPHCGAGA_00582 6e-105 pncA Q Isochorismatase family
NPHCGAGA_00583 2.9e-268 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPHCGAGA_00584 4.6e-126 3.6.1.13, 3.6.1.55 F NUDIX domain
NPHCGAGA_00586 5.6e-71 S Iron-sulphur cluster biosynthesis
NPHCGAGA_00588 7.7e-41 K LysR substrate binding domain
NPHCGAGA_00589 3.5e-60 K LysR substrate binding domain
NPHCGAGA_00590 2.5e-107 K Transcriptional regulator, LysR family
NPHCGAGA_00591 2.5e-166 arbZ I Phosphate acyltransferases
NPHCGAGA_00592 2.9e-160 arbY M Glycosyl transferase family 8
NPHCGAGA_00593 1.1e-183 arbY M Glycosyl transferase family 8
NPHCGAGA_00594 1.9e-142 arbx M Glycosyl transferase family 8
NPHCGAGA_00595 5.3e-128 arbV 2.3.1.51 I Acyl-transferase
NPHCGAGA_00596 1.2e-29 L transposase, IS605 OrfB family
NPHCGAGA_00597 1.9e-119
NPHCGAGA_00599 1.1e-33
NPHCGAGA_00601 2.8e-131 K response regulator
NPHCGAGA_00602 2e-306 vicK 2.7.13.3 T Histidine kinase
NPHCGAGA_00603 9.7e-242 yycH S YycH protein
NPHCGAGA_00604 2.2e-148 yycI S YycH protein
NPHCGAGA_00605 6.3e-148 vicX 3.1.26.11 S domain protein
NPHCGAGA_00606 6.3e-179 htrA 3.4.21.107 O serine protease
NPHCGAGA_00607 4.3e-91 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPHCGAGA_00608 1.3e-106 K Helix-turn-helix XRE-family like proteins
NPHCGAGA_00609 4.6e-100 S Bacteriocin helveticin-J
NPHCGAGA_00610 4.2e-78 S SLAP domain
NPHCGAGA_00611 1.5e-171 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
NPHCGAGA_00612 3.7e-90 P Cobalt transport protein
NPHCGAGA_00613 5.5e-245 cbiO1 S ABC transporter, ATP-binding protein
NPHCGAGA_00614 4.3e-172 K helix_turn_helix, arabinose operon control protein
NPHCGAGA_00615 5.6e-161 htpX O Belongs to the peptidase M48B family
NPHCGAGA_00616 2.3e-96 lemA S LemA family
NPHCGAGA_00617 8.3e-191 ybiR P Citrate transporter
NPHCGAGA_00618 2.9e-69 S Iron-sulphur cluster biosynthesis
NPHCGAGA_00619 3.1e-20 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NPHCGAGA_00620 6e-28 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_00621 7e-46
NPHCGAGA_00622 1.2e-53 S Domain of unknown function (DUF5067)
NPHCGAGA_00623 1.4e-62
NPHCGAGA_00624 5e-47
NPHCGAGA_00625 5.3e-144 2.4.2.3 F Phosphorylase superfamily
NPHCGAGA_00626 3.9e-30 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
NPHCGAGA_00627 2.5e-30 cdd 2.4.2.4, 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
NPHCGAGA_00629 2.2e-35 K Acetyltransferase (GNAT) domain
NPHCGAGA_00630 6.6e-46
NPHCGAGA_00631 6e-134
NPHCGAGA_00632 9e-181 EGP Major facilitator Superfamily
NPHCGAGA_00633 5.5e-101
NPHCGAGA_00634 2.2e-50 S Fic/DOC family
NPHCGAGA_00635 8.6e-60 S Fic/DOC family
NPHCGAGA_00636 2e-55
NPHCGAGA_00637 3.3e-87
NPHCGAGA_00638 1.3e-58 ypaA S Protein of unknown function (DUF1304)
NPHCGAGA_00639 2.5e-66 S Putative adhesin
NPHCGAGA_00640 6.3e-293 V ABC-type multidrug transport system, ATPase and permease components
NPHCGAGA_00641 5.6e-289 P ABC transporter
NPHCGAGA_00642 9.7e-61
NPHCGAGA_00643 3.1e-57 fic D Fic/DOC family
NPHCGAGA_00644 7e-17 fic D Fic/DOC family
NPHCGAGA_00645 9.4e-33
NPHCGAGA_00646 4.7e-254 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPHCGAGA_00647 2.5e-234 mepA V MATE efflux family protein
NPHCGAGA_00648 8.4e-79 S Threonine/Serine exporter, ThrE
NPHCGAGA_00649 4.4e-138 thrE S Putative threonine/serine exporter
NPHCGAGA_00650 1.9e-289 S ABC transporter
NPHCGAGA_00651 1e-55
NPHCGAGA_00652 1.4e-98 rimL J Acetyltransferase (GNAT) domain
NPHCGAGA_00653 2e-89 S Protein of unknown function (DUF554)
NPHCGAGA_00654 1.9e-13 S Protein of unknown function (DUF554)
NPHCGAGA_00655 8.1e-211 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPHCGAGA_00656 0.0 pepF E oligoendopeptidase F
NPHCGAGA_00657 4.8e-51 Z012_06740 S Fic/DOC family
NPHCGAGA_00658 1e-41 S Enterocin A Immunity
NPHCGAGA_00659 8.9e-33 lctP C L-lactate permease
NPHCGAGA_00660 5.9e-51 lctP C L-lactate permease
NPHCGAGA_00661 2.3e-51 lctP C L-lactate permease
NPHCGAGA_00662 4.2e-102 potB E Binding-protein-dependent transport system inner membrane component
NPHCGAGA_00663 3e-105 potC3 E Binding-protein-dependent transport system inner membrane component
NPHCGAGA_00664 3.3e-133 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPHCGAGA_00665 2.6e-141 potD2 P ABC transporter
NPHCGAGA_00666 3e-248 ade 3.5.4.2 F Adenine deaminase C-terminal domain
NPHCGAGA_00668 2.3e-71 gepA K Protein of unknown function (DUF4065)
NPHCGAGA_00669 1.1e-15 ps301 K Protein of unknown function (DUF4065)
NPHCGAGA_00670 0.0 yjbQ P TrkA C-terminal domain protein
NPHCGAGA_00671 7.6e-205 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NPHCGAGA_00672 4.5e-198 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPHCGAGA_00673 2.2e-169 S SLAP domain
NPHCGAGA_00674 2e-37 S Protein of unknown function (DUF2922)
NPHCGAGA_00675 7e-17
NPHCGAGA_00678 3.7e-85
NPHCGAGA_00679 3.2e-237 kup P Transport of potassium into the cell
NPHCGAGA_00680 1.9e-112 kup P Transport of potassium into the cell
NPHCGAGA_00681 1.1e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPHCGAGA_00682 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPHCGAGA_00683 2.3e-29 secG U Preprotein translocase
NPHCGAGA_00684 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPHCGAGA_00685 4.9e-177 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPHCGAGA_00686 1.3e-201 cpoA GT4 M Glycosyltransferase, group 1 family protein
NPHCGAGA_00687 2e-219 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NPHCGAGA_00715 1.2e-230 S Putative peptidoglycan binding domain
NPHCGAGA_00716 2.2e-91 S ECF-type riboflavin transporter, S component
NPHCGAGA_00717 7e-150 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NPHCGAGA_00718 4.1e-206 pbpX1 V Beta-lactamase
NPHCGAGA_00719 1.3e-105 lacA 2.3.1.79 S Transferase hexapeptide repeat
NPHCGAGA_00720 8.9e-113 3.6.1.27 I Acid phosphatase homologues
NPHCGAGA_00721 1.7e-78 C Flavodoxin
NPHCGAGA_00722 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NPHCGAGA_00723 7.6e-102 ktrB P Potassium uptake protein
NPHCGAGA_00724 3.1e-60 ktrB P Potassium uptake protein
NPHCGAGA_00725 4.8e-55 ktrA P domain protein
NPHCGAGA_00726 5.4e-44 ktrA P domain protein
NPHCGAGA_00727 1.9e-247 ynbB 4.4.1.1 P aluminum resistance
NPHCGAGA_00728 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NPHCGAGA_00729 2e-277 E Amino acid permease
NPHCGAGA_00730 1.9e-48 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
NPHCGAGA_00731 2.9e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPHCGAGA_00732 1.9e-65 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPHCGAGA_00733 1.4e-150 xerD L Phage integrase, N-terminal SAM-like domain
NPHCGAGA_00734 1.8e-58 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPHCGAGA_00735 5.8e-73 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NPHCGAGA_00736 5e-147 K Helix-turn-helix XRE-family like proteins
NPHCGAGA_00737 8.8e-154 2.5.1.140 E Belongs to the cysteine synthase cystathionine beta- synthase family
NPHCGAGA_00740 0.0 Q AMP-binding enzyme
NPHCGAGA_00741 1.4e-50 Q AMP-binding enzyme
NPHCGAGA_00742 1.8e-98 EGP Major facilitator Superfamily
NPHCGAGA_00743 5.5e-53 L Putative transposase DNA-binding domain
NPHCGAGA_00744 2.4e-56 L Putative transposase DNA-binding domain
NPHCGAGA_00746 2.8e-134 L Transposase and inactivated derivatives
NPHCGAGA_00747 3.7e-26 S Transposase C of IS166 homeodomain
NPHCGAGA_00748 7.9e-21 L PFAM IS66 Orf2 family protein
NPHCGAGA_00749 9.1e-23
NPHCGAGA_00750 1.2e-174 lacX 5.1.3.3 G Aldose 1-epimerase
NPHCGAGA_00751 9.4e-232 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPHCGAGA_00752 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPHCGAGA_00753 1.1e-167 xerC D Phage integrase, N-terminal SAM-like domain
NPHCGAGA_00754 3.6e-249 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPHCGAGA_00755 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPHCGAGA_00756 3.4e-152 dprA LU DNA protecting protein DprA
NPHCGAGA_00757 7e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPHCGAGA_00758 3.8e-159 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPHCGAGA_00759 1.4e-276 yjcE P Sodium proton antiporter
NPHCGAGA_00760 3.5e-35 yozE S Belongs to the UPF0346 family
NPHCGAGA_00761 9.4e-147 DegV S Uncharacterised protein, DegV family COG1307
NPHCGAGA_00762 4.4e-113 hlyIII S protein, hemolysin III
NPHCGAGA_00763 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPHCGAGA_00764 5.7e-158 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPHCGAGA_00765 6.6e-229 S Tetratricopeptide repeat protein
NPHCGAGA_00766 3.9e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPHCGAGA_00767 1.1e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NPHCGAGA_00768 1.7e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NPHCGAGA_00769 1.3e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NPHCGAGA_00770 2.4e-30 yocH M Lysin motif
NPHCGAGA_00771 1.3e-114 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPHCGAGA_00772 1.3e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPHCGAGA_00773 2.7e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPHCGAGA_00774 2.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPHCGAGA_00775 1.2e-58 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPHCGAGA_00776 4e-167 xerD D recombinase XerD
NPHCGAGA_00777 2e-161 cvfB S S1 domain
NPHCGAGA_00778 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NPHCGAGA_00779 6.6e-184 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPHCGAGA_00780 0.0 dnaE 2.7.7.7 L DNA polymerase
NPHCGAGA_00781 2.5e-22 S Protein of unknown function (DUF2929)
NPHCGAGA_00782 1.7e-303 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPHCGAGA_00783 7.6e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NPHCGAGA_00784 6.2e-33 yrvD S Lipopolysaccharide assembly protein A domain
NPHCGAGA_00785 6.1e-143 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPHCGAGA_00786 2.9e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPHCGAGA_00787 0.0 oatA I Acyltransferase
NPHCGAGA_00788 3.6e-241 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPHCGAGA_00789 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPHCGAGA_00790 1.9e-44 dedA 3.1.3.1 S SNARE associated Golgi protein
NPHCGAGA_00791 6.6e-246 yfnA E Amino Acid
NPHCGAGA_00792 1.6e-89 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHCGAGA_00793 3.1e-31 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHCGAGA_00794 7.8e-16 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPHCGAGA_00795 2.4e-139 yxeH S hydrolase
NPHCGAGA_00796 6.8e-110 S reductase
NPHCGAGA_00797 1.4e-19 S reductase
NPHCGAGA_00798 7.3e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPHCGAGA_00799 6.3e-221 patA 2.6.1.1 E Aminotransferase
NPHCGAGA_00800 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPHCGAGA_00801 1.1e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NPHCGAGA_00802 3.3e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPHCGAGA_00803 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPHCGAGA_00804 1.5e-59
NPHCGAGA_00805 7.2e-175 prmA J Ribosomal protein L11 methyltransferase
NPHCGAGA_00806 5.7e-86 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPHCGAGA_00807 2.3e-29 M domain protein
NPHCGAGA_00809 6.4e-26
NPHCGAGA_00810 1.8e-95 yxkA S Phosphatidylethanolamine-binding protein
NPHCGAGA_00811 4.3e-242 yjjP S Putative threonine/serine exporter
NPHCGAGA_00812 1.3e-168 citR K Putative sugar-binding domain
NPHCGAGA_00813 4.2e-53
NPHCGAGA_00814 1.4e-65 S Domain of unknown function DUF1828
NPHCGAGA_00815 1.3e-94 S UPF0397 protein
NPHCGAGA_00816 0.0 ykoD P ABC transporter, ATP-binding protein
NPHCGAGA_00817 6.8e-128 cbiQ P cobalt transport
NPHCGAGA_00818 9e-14
NPHCGAGA_00819 7.9e-71 yeaL S Protein of unknown function (DUF441)
NPHCGAGA_00820 7.9e-120 L Transposase
NPHCGAGA_00821 1.3e-87 L Transposase
NPHCGAGA_00822 2.9e-77 M1-431 S Protein of unknown function (DUF1706)
NPHCGAGA_00823 2.8e-91
NPHCGAGA_00824 1.9e-98 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NPHCGAGA_00825 7.9e-67 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NPHCGAGA_00826 1.8e-88 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NPHCGAGA_00827 8.2e-168 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NPHCGAGA_00828 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
NPHCGAGA_00829 1.7e-193 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NPHCGAGA_00830 4.2e-152 ydjP I Alpha/beta hydrolase family
NPHCGAGA_00831 4.1e-37 P Sodium:sulfate symporter transmembrane region
NPHCGAGA_00832 2.7e-257 pepC 3.4.22.40 E Peptidase C1-like family
NPHCGAGA_00833 6.1e-80
NPHCGAGA_00834 1.3e-11 fhaB M Rib/alpha-like repeat
NPHCGAGA_00835 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPHCGAGA_00836 1.1e-07 UW LPXTG-motif cell wall anchor domain protein
NPHCGAGA_00837 9.7e-43 M domain protein
NPHCGAGA_00839 2e-233 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPHCGAGA_00840 2e-161 L Transposase
NPHCGAGA_00841 1.1e-253 frdC 1.3.5.4 C FAD binding domain
NPHCGAGA_00842 2e-266 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPHCGAGA_00843 1.7e-34
NPHCGAGA_00844 6.4e-88 metI P ABC transporter permease
NPHCGAGA_00845 3.4e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPHCGAGA_00846 8.2e-162 metQ1 P Belongs to the nlpA lipoprotein family
NPHCGAGA_00847 0.0 aha1 P E1-E2 ATPase
NPHCGAGA_00848 2.1e-15 ps301 K sequence-specific DNA binding
NPHCGAGA_00849 4.4e-94 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPHCGAGA_00850 7e-186 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPHCGAGA_00851 5.4e-248 yifK E Amino acid permease
NPHCGAGA_00853 1e-58 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPHCGAGA_00854 2.2e-82 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPHCGAGA_00855 7.2e-98 3.6.1.27 I Acid phosphatase homologues
NPHCGAGA_00856 6.6e-132 yitS S Uncharacterised protein, DegV family COG1307
NPHCGAGA_00857 6.2e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPHCGAGA_00858 8.6e-65 S Domain of unknown function (DUF4767)
NPHCGAGA_00859 2.1e-85 C nitroreductase
NPHCGAGA_00860 6.1e-149 ypbG 2.7.1.2 GK ROK family
NPHCGAGA_00861 1.9e-277 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPHCGAGA_00862 3.7e-260 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHCGAGA_00863 1.2e-38
NPHCGAGA_00864 1.1e-122 gmuR K UTRA
NPHCGAGA_00865 3.2e-299 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPHCGAGA_00866 6.7e-69 S Domain of unknown function (DUF3284)
NPHCGAGA_00867 1.2e-15 gepA K Protein of unknown function (DUF4065)
NPHCGAGA_00868 2.8e-241 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHCGAGA_00869 4e-79
NPHCGAGA_00870 4.7e-58 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NPHCGAGA_00871 1.9e-53 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NPHCGAGA_00872 4.4e-115 K UTRA domain
NPHCGAGA_00873 2.5e-288 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPHCGAGA_00874 6.3e-168 S Aldo keto reductase
NPHCGAGA_00875 7e-175 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NPHCGAGA_00876 4e-79
NPHCGAGA_00877 3.2e-28 C FMN_bind
NPHCGAGA_00878 8.4e-301 I Protein of unknown function (DUF2974)
NPHCGAGA_00879 1.5e-55 3.6.1.55 F NUDIX domain
NPHCGAGA_00880 1.5e-203 pbpX1 V Beta-lactamase
NPHCGAGA_00881 2.3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPHCGAGA_00882 2e-214 aspC 2.6.1.1 E Aminotransferase
NPHCGAGA_00883 2.1e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPHCGAGA_00884 7.8e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPHCGAGA_00885 4e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPHCGAGA_00886 3.6e-78 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPHCGAGA_00887 3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPHCGAGA_00888 1.6e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPHCGAGA_00889 3.5e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPHCGAGA_00890 2.4e-273 yjeM E Amino Acid
NPHCGAGA_00891 6.4e-105 engB D Necessary for normal cell division and for the maintenance of normal septation
NPHCGAGA_00892 2.7e-100 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPHCGAGA_00893 6e-123 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPHCGAGA_00894 1.3e-209 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPHCGAGA_00895 4.7e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPHCGAGA_00896 5.4e-150
NPHCGAGA_00897 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPHCGAGA_00898 7e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPHCGAGA_00899 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
NPHCGAGA_00900 2.2e-171 holA 2.7.7.7 L DNA polymerase III delta subunit
NPHCGAGA_00901 0.0 comEC S Competence protein ComEC
NPHCGAGA_00902 7.3e-84 comEA L Competence protein ComEA
NPHCGAGA_00903 6.4e-193 ylbL T Belongs to the peptidase S16 family
NPHCGAGA_00904 2.7e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPHCGAGA_00905 1.9e-95 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NPHCGAGA_00906 4.3e-53 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NPHCGAGA_00907 1.4e-207 ftsW D Belongs to the SEDS family
NPHCGAGA_00908 0.0 typA T GTP-binding protein TypA
NPHCGAGA_00909 1.5e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPHCGAGA_00910 1.2e-32 ykzG S Belongs to the UPF0356 family
NPHCGAGA_00911 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPHCGAGA_00912 2.3e-193 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPHCGAGA_00913 2.1e-29 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NPHCGAGA_00914 4.8e-108 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NPHCGAGA_00915 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPHCGAGA_00916 3e-100 S Repeat protein
NPHCGAGA_00917 1.2e-123 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NPHCGAGA_00918 2.7e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPHCGAGA_00919 1.4e-56 XK27_04120 S Putative amino acid metabolism
NPHCGAGA_00920 3e-215 iscS 2.8.1.7 E Aminotransferase class V
NPHCGAGA_00921 3.8e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPHCGAGA_00922 4.6e-38
NPHCGAGA_00923 6.3e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NPHCGAGA_00924 2.1e-31 cspA K 'Cold-shock' DNA-binding domain
NPHCGAGA_00925 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPHCGAGA_00926 6.1e-95 gpsB D DivIVA domain protein
NPHCGAGA_00927 8.2e-148 ylmH S S4 domain protein
NPHCGAGA_00928 9e-47 yggT S YGGT family
NPHCGAGA_00929 4.8e-73 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPHCGAGA_00930 1.6e-204 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPHCGAGA_00931 5.7e-234 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPHCGAGA_00932 9.8e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPHCGAGA_00933 2.2e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPHCGAGA_00934 2.8e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPHCGAGA_00935 2.3e-176 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPHCGAGA_00936 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NPHCGAGA_00937 9.1e-54 ftsL D Cell division protein FtsL
NPHCGAGA_00938 3.4e-183 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPHCGAGA_00939 1.8e-77 mraZ K Belongs to the MraZ family
NPHCGAGA_00940 3.1e-69 L COG2826 Transposase and inactivated derivatives, IS30 family
NPHCGAGA_00941 1.2e-17 L Transposase and inactivated derivatives IS30 family
NPHCGAGA_00942 1.7e-84 L COG2826 Transposase and inactivated derivatives, IS30 family
NPHCGAGA_00943 1.9e-53 S Protein of unknown function (DUF3397)
NPHCGAGA_00944 2.5e-12 S Protein of unknown function (DUF4044)
NPHCGAGA_00945 4.9e-96 mreD
NPHCGAGA_00946 4.3e-147 mreC M Involved in formation and maintenance of cell shape
NPHCGAGA_00947 1.6e-172 mreB D cell shape determining protein MreB
NPHCGAGA_00948 3e-113 radC L DNA repair protein
NPHCGAGA_00949 2.2e-125 S Haloacid dehalogenase-like hydrolase
NPHCGAGA_00950 4e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPHCGAGA_00951 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPHCGAGA_00952 1e-101
NPHCGAGA_00953 1.4e-93 S Bacterial membrane protein, YfhO
NPHCGAGA_00954 1e-85 S Bacterial membrane protein, YfhO
NPHCGAGA_00955 1e-57 S Bacterial membrane protein, YfhO
NPHCGAGA_00956 8.9e-170 yfdH GT2 M Glycosyltransferase like family 2
NPHCGAGA_00957 2.4e-66 2.4.1.83 GT2 S GtrA-like protein
NPHCGAGA_00958 9.4e-211 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NPHCGAGA_00959 6.7e-23
NPHCGAGA_00960 1e-63 L Transposase
NPHCGAGA_00961 1.7e-44 repA S Replication initiator protein A
NPHCGAGA_00962 5.3e-25
NPHCGAGA_00963 5.4e-24 S Protein of unknown function (DUF2922)
NPHCGAGA_00964 1.7e-111 L Phage integrase, N-terminal SAM-like domain
NPHCGAGA_00965 3.5e-44 L Single-strand binding protein family
NPHCGAGA_00966 2e-138 L Replication initiation factor
NPHCGAGA_00967 6.5e-94 S Lysin motif
NPHCGAGA_00969 2e-106 S NgoFVII restriction endonuclease
NPHCGAGA_00970 9.1e-159 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
NPHCGAGA_00971 2.6e-55 vsr L DNA mismatch endonuclease Vsr
NPHCGAGA_00974 7.9e-137 M NlpC/P60 family
NPHCGAGA_00975 3e-126 M NlpC P60 family protein
NPHCGAGA_00976 2.2e-91 M NlpC/P60 family
NPHCGAGA_00977 1.2e-94 gmk2 2.7.4.8 F Guanylate kinase homologues.
NPHCGAGA_00978 3.7e-24
NPHCGAGA_00979 1.9e-275 S O-antigen ligase like membrane protein
NPHCGAGA_00980 6.3e-95
NPHCGAGA_00981 1e-66
NPHCGAGA_00982 1.7e-131 yvpB S Peptidase_C39 like family
NPHCGAGA_00983 5.4e-55 L transposase, IS605 OrfB family
NPHCGAGA_00985 2.6e-11 L Replication initiation factor
NPHCGAGA_00992 1.5e-78
NPHCGAGA_00993 4.5e-149 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NPHCGAGA_00994 3.7e-114 dedA S SNARE-like domain protein
NPHCGAGA_00995 2.1e-79 S Protein of unknown function (DUF1461)
NPHCGAGA_00996 2.9e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPHCGAGA_00997 2.7e-85 yutD S Protein of unknown function (DUF1027)
NPHCGAGA_00998 1.2e-276 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPHCGAGA_00999 1.1e-55
NPHCGAGA_01000 2.4e-264 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPHCGAGA_01001 6e-180 ccpA K catabolite control protein A
NPHCGAGA_01002 6.3e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPHCGAGA_01003 1e-44
NPHCGAGA_01004 2.1e-09 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPHCGAGA_01005 2.7e-149 ykuT M mechanosensitive ion channel
NPHCGAGA_01006 2.7e-114 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPHCGAGA_01007 2e-146 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPHCGAGA_01008 2.5e-68 yslB S Protein of unknown function (DUF2507)
NPHCGAGA_01009 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPHCGAGA_01010 4.6e-54 trxA O Belongs to the thioredoxin family
NPHCGAGA_01011 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPHCGAGA_01012 2.4e-50 yrzB S Belongs to the UPF0473 family
NPHCGAGA_01013 1e-72 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPHCGAGA_01014 2e-42 yrzL S Belongs to the UPF0297 family
NPHCGAGA_01015 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPHCGAGA_01016 1.4e-86
NPHCGAGA_01017 4.1e-70
NPHCGAGA_01018 5.2e-227 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPHCGAGA_01019 1.2e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NPHCGAGA_01020 5.6e-211 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPHCGAGA_01021 1.4e-283 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPHCGAGA_01022 2.2e-35 yajC U Preprotein translocase
NPHCGAGA_01023 2.8e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPHCGAGA_01024 3.5e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPHCGAGA_01025 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPHCGAGA_01026 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPHCGAGA_01027 3.3e-289 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPHCGAGA_01028 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPHCGAGA_01029 1.3e-88
NPHCGAGA_01030 1.6e-45
NPHCGAGA_01031 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
NPHCGAGA_01032 2e-229 scrB 3.2.1.26 GH32 G invertase
NPHCGAGA_01033 9.1e-181 scrR K Transcriptional regulator, LacI family
NPHCGAGA_01034 6.5e-123 liaI S membrane
NPHCGAGA_01035 2.4e-75 XK27_02470 K LytTr DNA-binding domain
NPHCGAGA_01036 5.2e-69 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPHCGAGA_01037 2.1e-28 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPHCGAGA_01038 0.0 uup S ABC transporter, ATP-binding protein
NPHCGAGA_01040 2.2e-66 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NPHCGAGA_01041 1.1e-83 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPHCGAGA_01042 7.9e-199 yfdE 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPHCGAGA_01043 1.4e-28 S Toxin ToxN, type III toxin-antitoxin system
NPHCGAGA_01044 3.2e-127 K UTRA
NPHCGAGA_01045 5.2e-181 S Oxidoreductase family, NAD-binding Rossmann fold
NPHCGAGA_01046 8.7e-125 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NPHCGAGA_01047 5.3e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPHCGAGA_01048 1.4e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NPHCGAGA_01049 3.4e-132 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NPHCGAGA_01050 9.9e-86 S ECF transporter, substrate-specific component
NPHCGAGA_01051 1.3e-126 fat 3.1.2.21 I Acyl-ACP thioesterase
NPHCGAGA_01052 2.2e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPHCGAGA_01053 2.7e-58 yabA L Involved in initiation control of chromosome replication
NPHCGAGA_01054 2.4e-153 holB 2.7.7.7 L DNA polymerase III
NPHCGAGA_01055 1.4e-50 yaaQ S Cyclic-di-AMP receptor
NPHCGAGA_01056 3.3e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPHCGAGA_01057 4.5e-33 S Protein of unknown function (DUF2508)
NPHCGAGA_01058 2.1e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPHCGAGA_01059 1.4e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPHCGAGA_01060 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPHCGAGA_01061 5e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPHCGAGA_01062 7.5e-112 rsmC 2.1.1.172 J Methyltransferase
NPHCGAGA_01063 1e-44 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
NPHCGAGA_01064 5e-29 rsmC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
NPHCGAGA_01065 5.4e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPHCGAGA_01066 1e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPHCGAGA_01067 3.3e-119 yfdV S Membrane transport protein
NPHCGAGA_01068 1.1e-22 yfdV S Membrane transport protein
NPHCGAGA_01069 3.6e-26 yfdV S Membrane transport protein
NPHCGAGA_01070 2.9e-117 phoU P Plays a role in the regulation of phosphate uptake
NPHCGAGA_01071 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPHCGAGA_01072 1.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPHCGAGA_01073 9.1e-156 pstA P Phosphate transport system permease protein PstA
NPHCGAGA_01074 7e-173 pstC P probably responsible for the translocation of the substrate across the membrane
NPHCGAGA_01075 9.5e-158 pstS P Phosphate
NPHCGAGA_01076 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPHCGAGA_01077 1.7e-67 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPHCGAGA_01078 3.1e-101 nusG K Participates in transcription elongation, termination and antitermination
NPHCGAGA_01079 5.9e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPHCGAGA_01080 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPHCGAGA_01081 4.9e-279 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NPHCGAGA_01082 8.3e-34
NPHCGAGA_01083 1.4e-93 sigH K Belongs to the sigma-70 factor family
NPHCGAGA_01084 7.8e-140 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPHCGAGA_01085 7.9e-76 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPHCGAGA_01086 5.6e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPHCGAGA_01087 3.4e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPHCGAGA_01088 1.7e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPHCGAGA_01089 2.8e-102 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NPHCGAGA_01090 4.9e-53
NPHCGAGA_01091 1.3e-265 pepC 3.4.22.40 E Peptidase C1-like family
NPHCGAGA_01092 3.5e-46
NPHCGAGA_01093 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPHCGAGA_01094 2.1e-182 S AAA domain
NPHCGAGA_01095 2.2e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPHCGAGA_01096 5.5e-23
NPHCGAGA_01097 2.5e-161 czcD P cation diffusion facilitator family transporter
NPHCGAGA_01098 2e-126 pgm3 G Belongs to the phosphoglycerate mutase family
NPHCGAGA_01099 6.4e-134 S membrane transporter protein
NPHCGAGA_01100 3.9e-111 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPHCGAGA_01101 2.3e-107 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NPHCGAGA_01102 9.3e-62 S Protein of unknown function (DUF805)
NPHCGAGA_01103 1.6e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
NPHCGAGA_01104 1.7e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPHCGAGA_01105 4.6e-143 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPHCGAGA_01106 1.8e-139 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHCGAGA_01107 1.5e-149 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHCGAGA_01108 1.7e-151 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPHCGAGA_01109 1.1e-60 rplQ J Ribosomal protein L17
NPHCGAGA_01110 1.8e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHCGAGA_01111 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPHCGAGA_01112 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPHCGAGA_01113 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NPHCGAGA_01114 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPHCGAGA_01115 6e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPHCGAGA_01116 6.9e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPHCGAGA_01117 4.5e-71 rplO J Binds to the 23S rRNA
NPHCGAGA_01118 2.3e-24 rpmD J Ribosomal protein L30
NPHCGAGA_01119 1.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPHCGAGA_01120 2.8e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPHCGAGA_01121 9.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPHCGAGA_01122 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPHCGAGA_01123 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPHCGAGA_01124 1.8e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPHCGAGA_01125 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPHCGAGA_01126 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPHCGAGA_01127 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPHCGAGA_01128 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NPHCGAGA_01129 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPHCGAGA_01130 1.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPHCGAGA_01131 2.6e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPHCGAGA_01132 3.5e-45 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPHCGAGA_01133 1.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPHCGAGA_01134 1.7e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPHCGAGA_01135 8.7e-105 rplD J Forms part of the polypeptide exit tunnel
NPHCGAGA_01136 6.9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPHCGAGA_01137 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NPHCGAGA_01138 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPHCGAGA_01139 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPHCGAGA_01140 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPHCGAGA_01141 2.1e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NPHCGAGA_01142 1.1e-30 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_01143 9.6e-64 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_01144 1e-80 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_01145 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHCGAGA_01146 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPHCGAGA_01147 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPHCGAGA_01148 2.9e-81 yebR 1.8.4.14 T GAF domain-containing protein
NPHCGAGA_01150 1.6e-08
NPHCGAGA_01151 4.6e-77
NPHCGAGA_01153 6.4e-298 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NPHCGAGA_01154 2.1e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPHCGAGA_01155 1.9e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPHCGAGA_01156 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPHCGAGA_01157 3.5e-238 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPHCGAGA_01158 3.5e-61 yabR J S1 RNA binding domain
NPHCGAGA_01159 9.8e-59 divIC D Septum formation initiator
NPHCGAGA_01160 1.8e-34 yabO J S4 domain protein
NPHCGAGA_01161 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPHCGAGA_01162 1.9e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPHCGAGA_01163 2.1e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPHCGAGA_01164 1.4e-127 S (CBS) domain
NPHCGAGA_01165 4.6e-92 K transcriptional regulator
NPHCGAGA_01166 1.4e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPHCGAGA_01167 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPHCGAGA_01168 1.8e-244 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPHCGAGA_01169 2.5e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPHCGAGA_01170 1.5e-39 rpmE2 J Ribosomal protein L31
NPHCGAGA_01171 2.7e-154 S Sucrose-6F-phosphate phosphohydrolase
NPHCGAGA_01172 3.4e-278 ybeC E amino acid
NPHCGAGA_01173 6.2e-227 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPHCGAGA_01174 2.9e-14 1.1.1.1 C nadph quinone reductase
NPHCGAGA_01175 2.7e-203 L transposase, IS605 OrfB family
NPHCGAGA_01177 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPHCGAGA_01178 1.3e-45 K Helix-turn-helix
NPHCGAGA_01179 1.1e-42 K DNA-binding helix-turn-helix protein
NPHCGAGA_01180 1e-53 K DNA-binding helix-turn-helix protein
NPHCGAGA_01181 2.2e-102 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPHCGAGA_01182 1.6e-222 pbuX F xanthine permease
NPHCGAGA_01183 1.4e-158 msmR K AraC-like ligand binding domain
NPHCGAGA_01184 5.3e-283 pipD E Dipeptidase
NPHCGAGA_01185 4.4e-22 S Haloacid dehalogenase-like hydrolase
NPHCGAGA_01186 4.3e-40 S Haloacid dehalogenase-like hydrolase
NPHCGAGA_01187 8.1e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPHCGAGA_01188 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPHCGAGA_01189 2.6e-52 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPHCGAGA_01190 4e-66 S Domain of unknown function (DUF1934)
NPHCGAGA_01191 4.8e-265 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPHCGAGA_01192 6.4e-21
NPHCGAGA_01193 9.4e-148 GK ROK family
NPHCGAGA_01194 3.9e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPHCGAGA_01195 3.2e-220 S SLAP domain
NPHCGAGA_01196 2.1e-103 S SLAP domain
NPHCGAGA_01197 1.8e-195 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPHCGAGA_01198 7.7e-149 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NPHCGAGA_01199 2.6e-37 veg S Biofilm formation stimulator VEG
NPHCGAGA_01200 9.4e-161 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPHCGAGA_01201 6.5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPHCGAGA_01202 2.3e-147 tatD L hydrolase, TatD family
NPHCGAGA_01203 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPHCGAGA_01204 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPHCGAGA_01205 1.5e-107 S TPM domain
NPHCGAGA_01206 1.6e-90 comEB 3.5.4.12 F MafB19-like deaminase
NPHCGAGA_01207 2.8e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPHCGAGA_01208 9.9e-114 E Belongs to the SOS response-associated peptidase family
NPHCGAGA_01210 4.9e-114
NPHCGAGA_01211 6.3e-76 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPHCGAGA_01212 7.6e-68 hsp O Belongs to the small heat shock protein (HSP20) family
NPHCGAGA_01213 1.1e-255 pepC 3.4.22.40 E aminopeptidase
NPHCGAGA_01214 9.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPHCGAGA_01215 1.8e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPHCGAGA_01216 2.9e-251 pepC 3.4.22.40 E aminopeptidase
NPHCGAGA_01218 2.2e-52
NPHCGAGA_01219 1.4e-242 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPHCGAGA_01220 1.2e-258 S Fibronectin type III domain
NPHCGAGA_01221 0.0 XK27_08315 M Sulfatase
NPHCGAGA_01222 2.8e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPHCGAGA_01223 3.4e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPHCGAGA_01224 1.3e-99 G Aldose 1-epimerase
NPHCGAGA_01225 1.9e-109 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPHCGAGA_01226 8.4e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPHCGAGA_01227 7.8e-132
NPHCGAGA_01228 3.8e-63 L Transposase
NPHCGAGA_01229 4.7e-115 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPHCGAGA_01230 3e-99 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NPHCGAGA_01231 1.1e-128 znuB U ABC 3 transport family
NPHCGAGA_01232 2.3e-116 fhuC P ABC transporter
NPHCGAGA_01233 6e-155 psaA P Belongs to the bacterial solute-binding protein 9 family
NPHCGAGA_01234 1.1e-40 K helix_turn_helix, Arsenical Resistance Operon Repressor
NPHCGAGA_01235 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
NPHCGAGA_01236 6.3e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPHCGAGA_01237 1.2e-138 fruR K DeoR C terminal sensor domain
NPHCGAGA_01240 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NPHCGAGA_01241 8.7e-27
NPHCGAGA_01242 7.1e-33
NPHCGAGA_01243 1.9e-33 yozG K Transcriptional regulator
NPHCGAGA_01244 4.8e-54 S Enterocin A Immunity
NPHCGAGA_01245 1.4e-12 S Enterocin A Immunity
NPHCGAGA_01246 1.4e-194 S Archaea bacterial proteins of unknown function
NPHCGAGA_01247 1.5e-135 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NPHCGAGA_01248 3.2e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPHCGAGA_01249 1.7e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
NPHCGAGA_01250 1.6e-120 K response regulator
NPHCGAGA_01251 0.0 V ABC transporter
NPHCGAGA_01252 1.5e-295 V ABC transporter, ATP-binding protein
NPHCGAGA_01253 6.4e-137 XK27_01040 S Protein of unknown function (DUF1129)
NPHCGAGA_01254 1.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPHCGAGA_01255 1.4e-43 yyzM S Bacterial protein of unknown function (DUF951)
NPHCGAGA_01256 5e-154 spo0J K Belongs to the ParB family
NPHCGAGA_01257 1.1e-136 soj D Sporulation initiation inhibitor
NPHCGAGA_01258 1.2e-146 noc K Belongs to the ParB family
NPHCGAGA_01259 1.6e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NPHCGAGA_01260 3.6e-83 cvpA S Colicin V production protein
NPHCGAGA_01261 8.6e-181 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPHCGAGA_01262 2.5e-149 3.1.3.48 T Tyrosine phosphatase family
NPHCGAGA_01263 5e-96 azr 1.5.1.36 S NADPH-dependent FMN reductase
NPHCGAGA_01264 1.8e-93 nqr 1.5.1.36 S NADPH-dependent FMN reductase
NPHCGAGA_01265 1.2e-109 K WHG domain
NPHCGAGA_01266 8e-38
NPHCGAGA_01267 3.9e-270 pipD E Dipeptidase
NPHCGAGA_01268 1.1e-116 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NPHCGAGA_01269 3.1e-166 hrtB V ABC transporter permease
NPHCGAGA_01270 7e-95 ygfC K Bacterial regulatory proteins, tetR family
NPHCGAGA_01271 7.9e-111 G phosphoglycerate mutase
NPHCGAGA_01272 5e-139 aroD S Alpha/beta hydrolase family
NPHCGAGA_01273 3e-139 S Belongs to the UPF0246 family
NPHCGAGA_01274 1.7e-119
NPHCGAGA_01275 2.7e-151 2.7.7.12 C Domain of unknown function (DUF4931)
NPHCGAGA_01276 1.4e-183 S Putative peptidoglycan binding domain
NPHCGAGA_01277 1.8e-24
NPHCGAGA_01278 5.9e-248 dtpT U amino acid peptide transporter
NPHCGAGA_01279 0.0 pepN 3.4.11.2 E aminopeptidase
NPHCGAGA_01280 5.3e-57 lysM M LysM domain
NPHCGAGA_01281 2.5e-170
NPHCGAGA_01282 6e-214 mdtG EGP Major facilitator Superfamily
NPHCGAGA_01283 2.4e-228 L Transposase
NPHCGAGA_01284 1.8e-13 ytgB S Transglycosylase associated protein
NPHCGAGA_01285 5.9e-52 K helix_turn_helix gluconate operon transcriptional repressor
NPHCGAGA_01286 2.7e-97 yieF S NADPH-dependent FMN reductase
NPHCGAGA_01287 1.2e-09 ymdB S Macro domain protein
NPHCGAGA_01288 1.6e-152 malG P ABC transporter permease
NPHCGAGA_01289 5.9e-247 malF P Binding-protein-dependent transport system inner membrane component
NPHCGAGA_01290 1.4e-210 malE G Bacterial extracellular solute-binding protein
NPHCGAGA_01291 8.3e-207 msmX P Belongs to the ABC transporter superfamily
NPHCGAGA_01292 4.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NPHCGAGA_01293 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NPHCGAGA_01294 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NPHCGAGA_01295 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NPHCGAGA_01296 2.9e-150 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPHCGAGA_01297 3e-173 yvdE K helix_turn _helix lactose operon repressor
NPHCGAGA_01298 3e-147 ptp2 3.1.3.48 T Tyrosine phosphatase family
NPHCGAGA_01299 6.2e-166 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPHCGAGA_01300 4.8e-85 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPHCGAGA_01301 2.1e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPHCGAGA_01303 9.3e-132 cobQ S glutamine amidotransferase
NPHCGAGA_01304 2.3e-81 M NlpC/P60 family
NPHCGAGA_01305 5.4e-151 EG EamA-like transporter family
NPHCGAGA_01306 9.3e-156 EG EamA-like transporter family
NPHCGAGA_01307 1.1e-107
NPHCGAGA_01308 2e-75
NPHCGAGA_01309 1.5e-113 XK27_05540 S DUF218 domain
NPHCGAGA_01310 7.4e-181 yheS_2 S ATPases associated with a variety of cellular activities
NPHCGAGA_01311 2e-80
NPHCGAGA_01312 8.8e-57
NPHCGAGA_01313 7.6e-244 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPHCGAGA_01314 3.3e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPHCGAGA_01315 5.7e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPHCGAGA_01318 2.2e-201 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NPHCGAGA_01319 2.2e-190 asnA 6.3.1.1 F aspartate--ammonia ligase
NPHCGAGA_01320 2.2e-236 steT_1 E amino acid
NPHCGAGA_01321 4.1e-138 puuD S peptidase C26
NPHCGAGA_01322 8.6e-246 yifK E Amino acid permease
NPHCGAGA_01323 4.1e-216 cycA E Amino acid permease
NPHCGAGA_01324 2e-127
NPHCGAGA_01325 9.3e-118 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPHCGAGA_01326 0.0 clpE O AAA domain (Cdc48 subfamily)
NPHCGAGA_01327 3.7e-168 S Alpha/beta hydrolase of unknown function (DUF915)
NPHCGAGA_01328 3.4e-223 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHCGAGA_01329 1.4e-119 XK27_06785 V ABC transporter, ATP-binding protein
NPHCGAGA_01330 2.2e-164 XK27_06780 V ABC transporter permease
NPHCGAGA_01331 3.6e-35
NPHCGAGA_01332 1.8e-282 ytgP S Polysaccharide biosynthesis protein
NPHCGAGA_01333 1.8e-149 lysA2 M Glycosyl hydrolases family 25
NPHCGAGA_01334 8.5e-122 S Protein of unknown function (DUF975)
NPHCGAGA_01335 1.7e-41
NPHCGAGA_01336 4.4e-81 S CAAX protease self-immunity
NPHCGAGA_01337 1.2e-10
NPHCGAGA_01338 5.1e-173 pbpX2 V Beta-lactamase
NPHCGAGA_01339 1e-248 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPHCGAGA_01340 5.7e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPHCGAGA_01341 9.2e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
NPHCGAGA_01342 1.4e-292 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPHCGAGA_01343 2.6e-18 S D-Ala-teichoic acid biosynthesis protein
NPHCGAGA_01344 3.2e-49
NPHCGAGA_01345 9.4e-214 ywhK S Membrane
NPHCGAGA_01346 3.9e-81 ykuL S (CBS) domain
NPHCGAGA_01347 0.0 cadA P P-type ATPase
NPHCGAGA_01348 7.2e-201 napA P Sodium/hydrogen exchanger family
NPHCGAGA_01349 1.7e-48 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NPHCGAGA_01350 1.6e-47 S YoeB-like toxin of bacterial type II toxin-antitoxin system
NPHCGAGA_01351 2.5e-281 V ABC transporter transmembrane region
NPHCGAGA_01352 2.5e-66 S Putative adhesin
NPHCGAGA_01353 1e-151 mutR K Helix-turn-helix XRE-family like proteins
NPHCGAGA_01354 8.4e-39
NPHCGAGA_01355 4.3e-118 S CAAX protease self-immunity
NPHCGAGA_01356 3.4e-192 S DUF218 domain
NPHCGAGA_01357 0.0 macB_3 V ABC transporter, ATP-binding protein
NPHCGAGA_01358 2.9e-97 S ECF transporter, substrate-specific component
NPHCGAGA_01359 1.7e-159 yeaE S Aldo/keto reductase family
NPHCGAGA_01360 2.2e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPHCGAGA_01361 1.8e-07 ybbH_2 K rpiR family
NPHCGAGA_01362 2.7e-117 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPHCGAGA_01363 1.5e-126 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPHCGAGA_01364 7.7e-146 cof S haloacid dehalogenase-like hydrolase
NPHCGAGA_01365 9.1e-229 pbuG S permease
NPHCGAGA_01366 6.5e-38 S cog cog1373
NPHCGAGA_01367 1.6e-150 S cog cog1373
NPHCGAGA_01368 1.3e-131 K helix_turn_helix, mercury resistance
NPHCGAGA_01369 1.7e-227 pbuG S permease
NPHCGAGA_01370 3.7e-244 S Uncharacterised protein family (UPF0236)
NPHCGAGA_01371 9.8e-239 amtB P ammonium transporter
NPHCGAGA_01372 1.5e-223 pbuG S permease
NPHCGAGA_01373 5.1e-35
NPHCGAGA_01374 2.7e-76 atkY K Penicillinase repressor
NPHCGAGA_01375 2e-64 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPHCGAGA_01376 1.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPHCGAGA_01377 0.0 copA 3.6.3.54 P P-type ATPase
NPHCGAGA_01378 8.2e-25 S CAAX protease self-immunity
NPHCGAGA_01379 1.3e-17
NPHCGAGA_01380 8.8e-209
NPHCGAGA_01381 1.8e-279 clcA P chloride
NPHCGAGA_01382 2.1e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPHCGAGA_01383 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NPHCGAGA_01384 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPHCGAGA_01385 3.6e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPHCGAGA_01386 3.9e-143 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPHCGAGA_01387 3.9e-60 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPHCGAGA_01388 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NPHCGAGA_01389 4.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPHCGAGA_01390 3.3e-195 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPHCGAGA_01391 1.7e-34 yaaA S S4 domain protein YaaA
NPHCGAGA_01392 9e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPHCGAGA_01393 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPHCGAGA_01394 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPHCGAGA_01395 4.2e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NPHCGAGA_01396 7.9e-75 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPHCGAGA_01397 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPHCGAGA_01398 1.1e-31 S SLAP domain
NPHCGAGA_01399 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NPHCGAGA_01400 2.2e-68 rplI J Binds to the 23S rRNA
NPHCGAGA_01401 2.7e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NPHCGAGA_01402 4.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
NPHCGAGA_01403 5e-173 degV S DegV family
NPHCGAGA_01404 1.9e-42 L transposase, IS605 OrfB family
NPHCGAGA_01405 1.5e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NPHCGAGA_01406 1e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPHCGAGA_01407 3.2e-178 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPHCGAGA_01408 4.4e-24
NPHCGAGA_01409 1.1e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPHCGAGA_01410 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPHCGAGA_01411 2.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPHCGAGA_01412 6.5e-133 comFC S Competence protein
NPHCGAGA_01413 4.7e-246 comFA L Helicase C-terminal domain protein
NPHCGAGA_01414 4.5e-115 yvyE 3.4.13.9 S YigZ family
NPHCGAGA_01415 2.5e-206 tagO 2.7.8.33, 2.7.8.35 M transferase
NPHCGAGA_01416 5.8e-217 rny S Endoribonuclease that initiates mRNA decay
NPHCGAGA_01417 1.4e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPHCGAGA_01418 1.9e-98 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPHCGAGA_01419 1.5e-139 ymfM S Helix-turn-helix domain
NPHCGAGA_01420 4e-133 IQ Enoyl-(Acyl carrier protein) reductase
NPHCGAGA_01421 1.1e-234 S Peptidase M16
NPHCGAGA_01422 7.9e-227 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NPHCGAGA_01423 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NPHCGAGA_01424 1.4e-68 WQ51_03320 S Protein of unknown function (DUF1149)
NPHCGAGA_01425 5.5e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPHCGAGA_01426 7.3e-209 yubA S AI-2E family transporter
NPHCGAGA_01427 1.9e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NPHCGAGA_01428 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
NPHCGAGA_01429 7.5e-202 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NPHCGAGA_01430 1.3e-109 S SNARE associated Golgi protein
NPHCGAGA_01431 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NPHCGAGA_01432 1.5e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPHCGAGA_01433 6e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPHCGAGA_01434 2.3e-113 yjbM 2.7.6.5 S RelA SpoT domain protein
NPHCGAGA_01435 1.2e-109 yjbK S CYTH
NPHCGAGA_01436 2.4e-110 yjbH Q Thioredoxin
NPHCGAGA_01437 5e-159 coiA 3.6.4.12 S Competence protein
NPHCGAGA_01438 1.1e-133 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPHCGAGA_01439 2.3e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPHCGAGA_01440 5.5e-306 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPHCGAGA_01441 8.5e-41 ptsH G phosphocarrier protein HPR
NPHCGAGA_01442 5.1e-27
NPHCGAGA_01443 0.0 clpE O Belongs to the ClpA ClpB family
NPHCGAGA_01444 2.5e-43 XK27_09445 S Domain of unknown function (DUF1827)
NPHCGAGA_01445 5.4e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPHCGAGA_01446 8.6e-159 hlyX S Transporter associated domain
NPHCGAGA_01447 2.5e-72
NPHCGAGA_01448 1.9e-86
NPHCGAGA_01449 1.9e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
NPHCGAGA_01450 4.7e-260 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPHCGAGA_01451 1.7e-47 tnpR1 L Resolvase, N terminal domain
NPHCGAGA_01452 1.5e-53 tnpR1 L Resolvase, N terminal domain
NPHCGAGA_01453 2.3e-19
NPHCGAGA_01456 1.7e-36
NPHCGAGA_01457 1.3e-20
NPHCGAGA_01458 1.4e-20 S DNA primase
NPHCGAGA_01459 1.4e-203 L COG2826 Transposase and inactivated derivatives, IS30 family
NPHCGAGA_01462 6e-97 L An automated process has identified a potential problem with this gene model
NPHCGAGA_01463 5.5e-46
NPHCGAGA_01464 1e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NPHCGAGA_01465 7.6e-223 L transposase, IS605 OrfB family
NPHCGAGA_01466 2.3e-167 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPHCGAGA_01467 1.1e-151 yihY S Belongs to the UPF0761 family
NPHCGAGA_01468 1.7e-164 map 3.4.11.18 E Methionine Aminopeptidase
NPHCGAGA_01469 1.3e-78 fld C Flavodoxin
NPHCGAGA_01470 5.3e-90 gtcA S Teichoic acid glycosylation protein
NPHCGAGA_01471 3.2e-214 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPHCGAGA_01472 7.9e-25
NPHCGAGA_01474 3.9e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHCGAGA_01475 1.2e-206 yfmL 3.6.4.13 L DEAD DEAH box helicase
NPHCGAGA_01476 3.7e-128 M Glycosyl hydrolases family 25
NPHCGAGA_01477 4.2e-226 potE E amino acid
NPHCGAGA_01478 6.3e-102 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPHCGAGA_01479 1.6e-236 yhdP S Transporter associated domain
NPHCGAGA_01480 5.2e-10 C nitroreductase
NPHCGAGA_01481 2.5e-18 C nitroreductase
NPHCGAGA_01482 6.2e-39
NPHCGAGA_01483 1.2e-85 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NPHCGAGA_01484 8.3e-74
NPHCGAGA_01485 5e-30 glvR K Helix-turn-helix domain, rpiR family
NPHCGAGA_01486 7e-60 glvR K Helix-turn-helix domain, rpiR family
NPHCGAGA_01487 0.0 glvC 2.7.1.199, 2.7.1.208 G phosphotransferase system, EIIB
NPHCGAGA_01488 2.4e-85 S hydrolase
NPHCGAGA_01489 1.5e-160 rssA S Phospholipase, patatin family
NPHCGAGA_01490 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NPHCGAGA_01491 1.1e-134 glcR K DeoR C terminal sensor domain
NPHCGAGA_01492 2.7e-58 S Enterocin A Immunity
NPHCGAGA_01493 4.3e-152 S hydrolase
NPHCGAGA_01494 5.7e-132 gntR K UbiC transcription regulator-associated domain protein
NPHCGAGA_01495 4.8e-176 rihB 3.2.2.1 F Nucleoside
NPHCGAGA_01496 0.0 kup P Transport of potassium into the cell
NPHCGAGA_01497 2.6e-126 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPHCGAGA_01498 1e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPHCGAGA_01499 2.2e-161 2.7.7.12 C Domain of unknown function (DUF4931)
NPHCGAGA_01500 6.7e-232 G Bacterial extracellular solute-binding protein
NPHCGAGA_01501 2.9e-90 S SLAP domain
NPHCGAGA_01502 2.6e-25 S Protein of unknown function (DUF2974)
NPHCGAGA_01503 1e-24 S Protein of unknown function (DUF2974)
NPHCGAGA_01504 4.7e-74 S Protein of unknown function (DUF2974)
NPHCGAGA_01505 7.5e-107 glnP P ABC transporter permease
NPHCGAGA_01506 5.1e-108 gluC P ABC transporter permease
NPHCGAGA_01507 9e-150 glnH ET ABC transporter substrate-binding protein
NPHCGAGA_01508 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPHCGAGA_01509 1.5e-112 udk 2.7.1.48 F Zeta toxin
NPHCGAGA_01510 1.2e-190 EGP Major facilitator superfamily
NPHCGAGA_01511 9.3e-101 S ABC-type cobalt transport system, permease component
NPHCGAGA_01512 0.0 V ABC transporter transmembrane region
NPHCGAGA_01513 2e-287 XK27_09600 V ABC transporter, ATP-binding protein
NPHCGAGA_01514 5.1e-81 K Transcriptional regulator, MarR family
NPHCGAGA_01515 1.6e-146 glnH ET ABC transporter
NPHCGAGA_01516 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NPHCGAGA_01517 1.4e-56
NPHCGAGA_01518 1.2e-16
NPHCGAGA_01519 2.7e-29
NPHCGAGA_01520 1.9e-308 ybiT S ABC transporter, ATP-binding protein
NPHCGAGA_01521 3.9e-209 pepA E M42 glutamyl aminopeptidase
NPHCGAGA_01522 9.6e-217 mdtG EGP Major facilitator Superfamily
NPHCGAGA_01523 1.5e-259 emrY EGP Major facilitator Superfamily
NPHCGAGA_01524 2e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPHCGAGA_01525 8.9e-240 pyrP F Permease
NPHCGAGA_01526 4.4e-29
NPHCGAGA_01527 1.5e-77 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_01528 1.1e-27 L COG2963 Transposase and inactivated derivatives
NPHCGAGA_01529 3.9e-101 pncA Q Isochorismatase family
NPHCGAGA_01530 6.9e-23 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NPHCGAGA_01531 2e-89
NPHCGAGA_01532 1e-75 2.3.1.128 K Acetyltransferase (GNAT) domain
NPHCGAGA_01533 6.1e-70 4.2.1.53 S MCRA family
NPHCGAGA_01534 1.8e-209 4.2.1.53 S Myosin-crossreactive antigen
NPHCGAGA_01535 6.3e-18 yxdD K Bacterial regulatory proteins, tetR family
NPHCGAGA_01536 3.1e-241 emrY EGP Major facilitator Superfamily
NPHCGAGA_01541 4.6e-96 MA20_25245 K Acetyltransferase (GNAT) domain
NPHCGAGA_01543 1e-27 cspA K Cold shock protein
NPHCGAGA_01544 7.3e-109 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NPHCGAGA_01545 2.1e-123 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPHCGAGA_01546 2.6e-27 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPHCGAGA_01547 1.1e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPHCGAGA_01548 4.6e-247 nhaC C Na H antiporter NhaC
NPHCGAGA_01549 5.6e-53
NPHCGAGA_01550 1.4e-119 ybhL S Belongs to the BI1 family
NPHCGAGA_01551 9.7e-113 S Protein of unknown function (DUF1211)
NPHCGAGA_01552 3e-170 yegS 2.7.1.107 G Lipid kinase
NPHCGAGA_01553 6.4e-276 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPHCGAGA_01554 4.2e-259 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPHCGAGA_01555 2.9e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPHCGAGA_01556 1.1e-206 camS S sex pheromone
NPHCGAGA_01557 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPHCGAGA_01558 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NPHCGAGA_01559 2.9e-103 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NPHCGAGA_01561 5.3e-86 ydcK S Belongs to the SprT family
NPHCGAGA_01562 2.2e-133 M Glycosyltransferase sugar-binding region containing DXD motif
NPHCGAGA_01563 7.1e-259 epsU S Polysaccharide biosynthesis protein
NPHCGAGA_01564 2.1e-224 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPHCGAGA_01565 1.4e-44 pacL 3.6.3.8 P P-type ATPase
NPHCGAGA_01566 2e-21 pacL 3.6.3.8 P P-type ATPase
NPHCGAGA_01567 7e-295 pacL 3.6.3.8 P P-type ATPase
NPHCGAGA_01568 3.9e-62 pacL 3.6.3.8 P P-type ATPase
NPHCGAGA_01569 6.6e-221 L Probable transposase
NPHCGAGA_01570 1.8e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPHCGAGA_01571 2.8e-282 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPHCGAGA_01572 1.8e-201 csaB M Glycosyl transferases group 1
NPHCGAGA_01573 1.2e-132 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPHCGAGA_01574 1.2e-18 S SLAP domain
NPHCGAGA_01576 0.0 1.3.5.4 C FAD binding domain
NPHCGAGA_01577 9.5e-65 K Helix-turn-helix XRE-family like proteins
NPHCGAGA_01578 7.6e-62 K Helix-turn-helix XRE-family like proteins
NPHCGAGA_01579 1.6e-49 K Helix-turn-helix XRE-family like proteins
NPHCGAGA_01580 7.4e-117
NPHCGAGA_01582 1e-83 S Protein of unknown function (DUF3232)
NPHCGAGA_01583 1.9e-84 D nuclear chromosome segregation
NPHCGAGA_01584 2.9e-175 S SLAP domain
NPHCGAGA_01585 6.4e-111 K Helix-turn-helix XRE-family like proteins
NPHCGAGA_01586 4.6e-124
NPHCGAGA_01587 3.3e-65
NPHCGAGA_01588 1.2e-27 K Helix-turn-helix XRE-family like proteins
NPHCGAGA_01589 5.4e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPHCGAGA_01590 1.2e-141 K Helix-turn-helix domain
NPHCGAGA_01591 1.3e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPHCGAGA_01592 1.6e-216 iscS2 2.8.1.7 E Aminotransferase class V
NPHCGAGA_01593 1.7e-280 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPHCGAGA_01594 2e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPHCGAGA_01595 1.9e-80 yueI S Protein of unknown function (DUF1694)
NPHCGAGA_01596 4.4e-239 rarA L recombination factor protein RarA
NPHCGAGA_01597 2.5e-35
NPHCGAGA_01598 2.3e-78 usp6 T universal stress protein
NPHCGAGA_01599 1.9e-217 rodA D Belongs to the SEDS family
NPHCGAGA_01600 2.5e-33 S Protein of unknown function (DUF2969)
NPHCGAGA_01601 7.2e-49 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NPHCGAGA_01602 3e-176 mbl D Cell shape determining protein MreB Mrl
NPHCGAGA_01603 3.4e-30 ywzB S Protein of unknown function (DUF1146)
NPHCGAGA_01604 2.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NPHCGAGA_01605 3.5e-242 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPHCGAGA_01606 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPHCGAGA_01607 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPHCGAGA_01608 4.9e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPHCGAGA_01609 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPHCGAGA_01610 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPHCGAGA_01611 3.8e-128 atpB C it plays a direct role in the translocation of protons across the membrane
NPHCGAGA_01612 2.6e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPHCGAGA_01613 2.7e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPHCGAGA_01614 3.9e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPHCGAGA_01615 6.9e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPHCGAGA_01616 2.2e-113 tdk 2.7.1.21 F thymidine kinase
NPHCGAGA_01617 1e-246 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NPHCGAGA_01620 4.6e-196 ampC V Beta-lactamase
NPHCGAGA_01621 8.3e-134 EGP Major facilitator Superfamily
NPHCGAGA_01622 3.2e-21 EGP Major facilitator Superfamily
NPHCGAGA_01623 1.1e-15 EGP Major facilitator Superfamily
NPHCGAGA_01624 9.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NPHCGAGA_01625 8.3e-108 vanZ V VanZ like family
NPHCGAGA_01626 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPHCGAGA_01627 6.9e-270 yclK 2.7.13.3 T Histidine kinase
NPHCGAGA_01628 3.5e-129 K Transcriptional regulatory protein, C terminal
NPHCGAGA_01629 7.1e-60 S SdpI/YhfL protein family
NPHCGAGA_01630 1.7e-168 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPHCGAGA_01631 8.1e-171 patB 4.4.1.8 E Aminotransferase, class I
NPHCGAGA_01632 1.1e-36 patB 4.4.1.8 E Aminotransferase, class I
NPHCGAGA_01633 5e-67 M Protein of unknown function (DUF3737)
NPHCGAGA_01635 6.8e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPHCGAGA_01636 5.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
NPHCGAGA_01637 7.8e-80 comGF U Putative Competence protein ComGF
NPHCGAGA_01638 1.7e-41
NPHCGAGA_01639 2.1e-73
NPHCGAGA_01640 1.4e-43 comGC U competence protein ComGC
NPHCGAGA_01641 1.9e-173 comGB NU type II secretion system
NPHCGAGA_01642 2.3e-176 comGA NU Type II IV secretion system protein
NPHCGAGA_01643 2.6e-132 yebC K Transcriptional regulatory protein
NPHCGAGA_01644 4.3e-89 S VanZ like family
NPHCGAGA_01645 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPHCGAGA_01647 1.5e-289 E Amino acid permease
NPHCGAGA_01648 4e-181 D Alpha beta
NPHCGAGA_01649 5e-300 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPHCGAGA_01650 0.0 bglP G phosphotransferase system
NPHCGAGA_01651 1.8e-142 licT K CAT RNA binding domain
NPHCGAGA_01652 6.2e-213 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NPHCGAGA_01653 4.9e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPHCGAGA_01654 1.9e-116
NPHCGAGA_01655 5.4e-147 S Sucrose-6F-phosphate phosphohydrolase
NPHCGAGA_01656 5.8e-149 S hydrolase
NPHCGAGA_01657 5.3e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPHCGAGA_01658 2.8e-171 ybbR S YbbR-like protein
NPHCGAGA_01659 1.2e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPHCGAGA_01660 3.4e-205 potD P ABC transporter
NPHCGAGA_01661 1.4e-123 potC P ABC transporter permease
NPHCGAGA_01662 7.9e-130 potB P ABC transporter permease
NPHCGAGA_01663 2.3e-201 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPHCGAGA_01664 7e-164 murB 1.3.1.98 M Cell wall formation
NPHCGAGA_01665 1.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
NPHCGAGA_01666 6.4e-90 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NPHCGAGA_01667 7.3e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NPHCGAGA_01668 1.7e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPHCGAGA_01669 7.7e-152 ycsE S Sucrose-6F-phosphate phosphohydrolase
NPHCGAGA_01670 5.3e-95
NPHCGAGA_01671 1.2e-143 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPHCGAGA_01672 2.7e-227 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NPHCGAGA_01673 5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPHCGAGA_01674 1.2e-188 cggR K Putative sugar-binding domain
NPHCGAGA_01676 6.5e-142
NPHCGAGA_01677 1.6e-63
NPHCGAGA_01678 2.2e-33
NPHCGAGA_01679 1e-146 ycaM E amino acid
NPHCGAGA_01680 3.4e-49 ycaM E amino acid
NPHCGAGA_01681 3.6e-151 S haloacid dehalogenase-like hydrolase
NPHCGAGA_01682 0.0 S SH3-like domain
NPHCGAGA_01683 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPHCGAGA_01684 1.1e-170 whiA K May be required for sporulation
NPHCGAGA_01685 5.4e-192 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NPHCGAGA_01686 3.1e-164 rapZ S Displays ATPase and GTPase activities
NPHCGAGA_01687 4.5e-81 S Short repeat of unknown function (DUF308)
NPHCGAGA_01688 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPHCGAGA_01689 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPHCGAGA_01690 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPHCGAGA_01691 2e-61 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NPHCGAGA_01692 5.9e-41 L transposase, IS605 OrfB family
NPHCGAGA_01693 5e-43 L transposase, IS605 OrfB family
NPHCGAGA_01694 9e-14 S C4-dicarboxylate anaerobic carrier
NPHCGAGA_01695 1.5e-92 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPHCGAGA_01696 5.3e-23
NPHCGAGA_01697 1.7e-99 S LexA-binding, inner membrane-associated putative hydrolase
NPHCGAGA_01698 3e-37
NPHCGAGA_01699 6.7e-187 tdh 1.1.1.14 C Zinc-binding dehydrogenase
NPHCGAGA_01702 2e-28 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NPHCGAGA_01703 3.7e-54 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NPHCGAGA_01704 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
NPHCGAGA_01705 1.2e-185 V Beta-lactamase
NPHCGAGA_01706 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NPHCGAGA_01707 1.4e-49 K HxlR-like helix-turn-helix
NPHCGAGA_01708 6.9e-43 yqiG C Oxidoreductase
NPHCGAGA_01709 7.3e-50 yqiG C Oxidoreductase
NPHCGAGA_01710 1.1e-66 yqiG C Oxidoreductase
NPHCGAGA_01711 3.7e-19 I carboxylic ester hydrolase activity
NPHCGAGA_01712 1.4e-55 I carboxylic ester hydrolase activity
NPHCGAGA_01713 1.2e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NPHCGAGA_01714 2.2e-28 1.1.1.3 T phosphoserine phosphatase activity
NPHCGAGA_01715 6.7e-68 XK27_08635 S UPF0210 protein
NPHCGAGA_01716 1.1e-52 XK27_08635 S UPF0210 protein
NPHCGAGA_01717 2.5e-11 snf 2.7.11.1 KL domain protein
NPHCGAGA_01718 4.9e-50 snf 2.7.11.1 KL domain protein
NPHCGAGA_01719 2.3e-158 snf 2.7.11.1 KL domain protein
NPHCGAGA_01720 7.3e-202 snf 2.7.11.1 KL domain protein
NPHCGAGA_01721 4.7e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPHCGAGA_01722 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPHCGAGA_01723 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPHCGAGA_01724 1.5e-167 K Transcriptional regulator
NPHCGAGA_01725 2.8e-163 ppaC 3.6.1.1 C inorganic pyrophosphatase
NPHCGAGA_01726 5.9e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NPHCGAGA_01727 6.8e-54 K Helix-turn-helix domain
NPHCGAGA_01728 6.7e-57 yoaK S Protein of unknown function (DUF1275)
NPHCGAGA_01729 1.2e-33 M Glycosyl hydrolases family 25
NPHCGAGA_01730 4.2e-78 M Glycosyl hydrolases family 25
NPHCGAGA_01731 2.4e-27 M Glycosyl hydrolases family 25
NPHCGAGA_01732 6.9e-17 XK27_00160 S Domain of unknown function (DUF5052)
NPHCGAGA_01733 9.4e-68 XK27_00160 S Domain of unknown function (DUF5052)
NPHCGAGA_01734 5.6e-26 adk 2.7.4.3 F topology modulation protein
NPHCGAGA_01735 5.3e-67
NPHCGAGA_01736 1.7e-204 xerS L Belongs to the 'phage' integrase family
NPHCGAGA_01737 1.9e-158 degV S EDD domain protein, DegV family
NPHCGAGA_01738 3.8e-64
NPHCGAGA_01739 0.0 FbpA K Fibronectin-binding protein
NPHCGAGA_01740 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NPHCGAGA_01741 1.9e-197 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPHCGAGA_01742 1.3e-152 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPHCGAGA_01743 2.8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPHCGAGA_01744 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPHCGAGA_01745 7.9e-230 cpdA S Calcineurin-like phosphoesterase
NPHCGAGA_01746 6.9e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NPHCGAGA_01747 5.2e-69 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPHCGAGA_01748 2.3e-104 ypsA S Belongs to the UPF0398 family
NPHCGAGA_01749 1.3e-116 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPHCGAGA_01750 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NPHCGAGA_01751 2.5e-112 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPHCGAGA_01752 7.4e-115 dnaD L DnaD domain protein
NPHCGAGA_01753 1.5e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NPHCGAGA_01754 1.6e-88 ypmB S Protein conserved in bacteria
NPHCGAGA_01755 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPHCGAGA_01756 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NPHCGAGA_01757 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPHCGAGA_01758 9.9e-166 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NPHCGAGA_01759 2.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NPHCGAGA_01760 4.2e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NPHCGAGA_01761 2.6e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPHCGAGA_01762 1.8e-259 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NPHCGAGA_01763 4.4e-175
NPHCGAGA_01764 4.3e-138
NPHCGAGA_01765 1e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPHCGAGA_01766 7.8e-28
NPHCGAGA_01767 1.3e-246 rarA L recombination factor protein RarA
NPHCGAGA_01768 1.2e-112
NPHCGAGA_01769 3.8e-140
NPHCGAGA_01770 3.8e-143
NPHCGAGA_01771 3.4e-121 skfE V ATPases associated with a variety of cellular activities
NPHCGAGA_01772 1.5e-59 yvoA_1 K Transcriptional regulator, GntR family
NPHCGAGA_01773 1.8e-242 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPHCGAGA_01774 1e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPHCGAGA_01775 1.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NPHCGAGA_01776 2.3e-67 mutT 3.6.1.55 F NUDIX domain
NPHCGAGA_01777 1.4e-124 S Peptidase family M23
NPHCGAGA_01778 1.2e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPHCGAGA_01779 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPHCGAGA_01780 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NPHCGAGA_01781 3.9e-178 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NPHCGAGA_01782 1.7e-134 recO L Involved in DNA repair and RecF pathway recombination
NPHCGAGA_01783 1.8e-55 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NPHCGAGA_01784 1.6e-123 gntR1 K UTRA
NPHCGAGA_01785 6e-213
NPHCGAGA_01788 1.4e-87
NPHCGAGA_01790 5.4e-267 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NPHCGAGA_01791 3.2e-211 msmX P Belongs to the ABC transporter superfamily
NPHCGAGA_01792 9.5e-255 sacA 3.2.1.26 GH32 G Glycosyl hydrolases family 32
NPHCGAGA_01793 3.3e-155 msmG G Binding-protein-dependent transport system inner membrane component
NPHCGAGA_01794 4.5e-163 msmF P ABC-type sugar transport systems, permease components
NPHCGAGA_01795 7.3e-239 msmE G Bacterial extracellular solute-binding protein
NPHCGAGA_01796 6.2e-182 msmR K helix_turn _helix lactose operon repressor
NPHCGAGA_01797 3.3e-129 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPHCGAGA_01798 7.6e-115 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NPHCGAGA_01799 7.7e-103 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NPHCGAGA_01800 2.6e-111 G Phosphoglycerate mutase family
NPHCGAGA_01801 1.3e-196 D nuclear chromosome segregation
NPHCGAGA_01802 7.3e-52 M LysM domain protein
NPHCGAGA_01803 5.6e-13
NPHCGAGA_01804 6.9e-156 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NPHCGAGA_01805 7.8e-67
NPHCGAGA_01806 7.1e-32
NPHCGAGA_01807 4.1e-71 S Iron-sulphur cluster biosynthesis
NPHCGAGA_01808 2.2e-28 K Transcriptional regulator
NPHCGAGA_01809 1.2e-227 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPHCGAGA_01810 4.2e-127 XK27_08435 K UTRA
NPHCGAGA_01812 1e-215 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPHCGAGA_01813 2.3e-155 CE10 I Belongs to the type-B carboxylesterase lipase family
NPHCGAGA_01814 1.5e-232 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPHCGAGA_01815 1.3e-121 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPHCGAGA_01816 1.5e-23 pts15B 2.7.1.196, 2.7.1.205 G PTS family porter, IIB component
NPHCGAGA_01817 8.5e-25 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
NPHCGAGA_01818 1.3e-19 S Domain of unknown function (DUF3284)
NPHCGAGA_01819 7.1e-132 K Psort location Cytoplasmic, score 8.87
NPHCGAGA_01820 4.4e-86 C FAD binding domain
NPHCGAGA_01821 3.5e-25 C FAD binding domain
NPHCGAGA_01822 1.2e-47 C FAD binding domain
NPHCGAGA_01824 1.7e-139 S Uncharacterized protein conserved in bacteria (DUF2263)
NPHCGAGA_01825 5.1e-60
NPHCGAGA_01826 0.0 lhr L DEAD DEAH box helicase
NPHCGAGA_01827 1.2e-249 P P-loop Domain of unknown function (DUF2791)
NPHCGAGA_01828 2.8e-260 S TerB-C domain
NPHCGAGA_01829 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NPHCGAGA_01830 2.8e-30 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NPHCGAGA_01831 2.9e-37
NPHCGAGA_01832 3.1e-133 4.1.1.44 S Carboxymuconolactone decarboxylase family
NPHCGAGA_01833 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPHCGAGA_01834 5.6e-36 S LPXTG cell wall anchor motif
NPHCGAGA_01835 6.8e-46 UW LPXTG-motif cell wall anchor domain protein
NPHCGAGA_01836 2.8e-79
NPHCGAGA_01837 1.8e-38
NPHCGAGA_01838 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPHCGAGA_01839 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NPHCGAGA_01840 1.1e-237 cycA E Amino acid permease
NPHCGAGA_01841 2.4e-84 maa S transferase hexapeptide repeat
NPHCGAGA_01842 1.5e-127 K Transcriptional regulator
NPHCGAGA_01843 3.2e-62 manO S Domain of unknown function (DUF956)
NPHCGAGA_01844 1.6e-171 manN G system, mannose fructose sorbose family IID component
NPHCGAGA_01845 1.5e-133 manY G PTS system
NPHCGAGA_01846 4.6e-188 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NPHCGAGA_01848 1.6e-137 L transposase, IS605 OrfB family
NPHCGAGA_01849 0.0 pepO 3.4.24.71 O Peptidase family M13
NPHCGAGA_01850 4.3e-225 yttB EGP Major facilitator Superfamily
NPHCGAGA_01851 2.4e-228 XK27_04775 S PAS domain
NPHCGAGA_01852 4.5e-100 S Iron-sulfur cluster assembly protein
NPHCGAGA_01853 9.6e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPHCGAGA_01854 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NPHCGAGA_01857 4.7e-254 yxbA 6.3.1.12 S ATP-grasp enzyme
NPHCGAGA_01858 0.0 asnB 6.3.5.4 E Asparagine synthase
NPHCGAGA_01859 1.4e-272 S Calcineurin-like phosphoesterase
NPHCGAGA_01860 3.6e-82
NPHCGAGA_01861 4.3e-106 tag 3.2.2.20 L glycosylase
NPHCGAGA_01862 4.6e-146 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NPHCGAGA_01863 6.1e-127 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NPHCGAGA_01864 3.7e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NPHCGAGA_01865 1.6e-150 phnD P Phosphonate ABC transporter
NPHCGAGA_01866 8.5e-87 uspA T universal stress protein
NPHCGAGA_01867 7e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
NPHCGAGA_01868 5e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPHCGAGA_01869 5.7e-80 ntd 2.4.2.6 F Nucleoside
NPHCGAGA_01870 0.0 G Belongs to the glycosyl hydrolase 31 family
NPHCGAGA_01871 1.5e-255 L Probable transposase
NPHCGAGA_01872 1.3e-105 L Resolvase, N terminal domain
NPHCGAGA_01873 3.4e-25
NPHCGAGA_01874 8.4e-156 I alpha/beta hydrolase fold
NPHCGAGA_01875 6.4e-129 yibF S overlaps another CDS with the same product name
NPHCGAGA_01876 4.5e-200 yibE S overlaps another CDS with the same product name
NPHCGAGA_01877 2.7e-92
NPHCGAGA_01878 9e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPHCGAGA_01879 6e-230 S Cysteine-rich secretory protein family
NPHCGAGA_01880 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPHCGAGA_01881 6e-261 glnPH2 P ABC transporter permease
NPHCGAGA_01882 1.5e-128
NPHCGAGA_01883 3.9e-122 luxT K Bacterial regulatory proteins, tetR family
NPHCGAGA_01884 2.9e-179 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPHCGAGA_01885 1.8e-53
NPHCGAGA_01886 2.8e-114 GM NmrA-like family
NPHCGAGA_01887 2.5e-126 S Alpha/beta hydrolase family
NPHCGAGA_01888 1.2e-157 epsV 2.7.8.12 S glycosyl transferase family 2
NPHCGAGA_01889 1.2e-134 ypuA S Protein of unknown function (DUF1002)
NPHCGAGA_01890 1.1e-144 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPHCGAGA_01891 1.4e-175 S Alpha/beta hydrolase of unknown function (DUF915)
NPHCGAGA_01892 2.7e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPHCGAGA_01893 5.9e-85
NPHCGAGA_01894 9.8e-129 cobB K SIR2 family
NPHCGAGA_01895 3.9e-90 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NPHCGAGA_01896 2.5e-120 terC P Integral membrane protein TerC family
NPHCGAGA_01897 2.4e-62 yeaO S Protein of unknown function, DUF488
NPHCGAGA_01898 2.8e-122 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NPHCGAGA_01899 8.7e-290 glnP P ABC transporter permease
NPHCGAGA_01900 6.8e-136 glnQ E ABC transporter, ATP-binding protein
NPHCGAGA_01901 1.8e-156 L HNH nucleases
NPHCGAGA_01902 5.9e-120 yfbR S HD containing hydrolase-like enzyme
NPHCGAGA_01904 1.1e-153 G Glycosyl hydrolases family 8
NPHCGAGA_01905 1.3e-171 ydaM M Glycosyl transferase family group 2
NPHCGAGA_01906 1.8e-43 M Glycosyl transferase
NPHCGAGA_01907 1.8e-72
NPHCGAGA_01908 1.2e-17
NPHCGAGA_01909 3.2e-31 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NPHCGAGA_01910 4.3e-107 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)