ORF_ID e_value Gene_name EC_number CAZy COGs Description
JOCLAFEN_00001 3.3e-98 thiT S Thiamine transporter protein (Thia_YuaJ)
JOCLAFEN_00002 1.9e-177 yuaG 3.4.21.72 S protein conserved in bacteria
JOCLAFEN_00003 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
JOCLAFEN_00004 1.4e-81 yuaE S DinB superfamily
JOCLAFEN_00005 2.5e-109 yuaD S MOSC domain
JOCLAFEN_00006 6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
JOCLAFEN_00007 2.1e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
JOCLAFEN_00008 6e-97 yuaC K Belongs to the GbsR family
JOCLAFEN_00009 2.1e-94 yuaB
JOCLAFEN_00010 9.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
JOCLAFEN_00011 4.3e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JOCLAFEN_00012 3.8e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JOCLAFEN_00013 3.3e-123 G Cupin
JOCLAFEN_00014 8.8e-10 yjcN
JOCLAFEN_00016 5.7e-15
JOCLAFEN_00019 1.7e-130 S Aspartate phosphatase response regulator
JOCLAFEN_00020 3.6e-15
JOCLAFEN_00021 1e-39
JOCLAFEN_00023 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
JOCLAFEN_00024 9e-196 yubA S transporter activity
JOCLAFEN_00025 1e-184 ygjR S Oxidoreductase
JOCLAFEN_00026 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
JOCLAFEN_00027 7.6e-235 mcpA NT chemotaxis protein
JOCLAFEN_00028 1.2e-224 mcpA NT chemotaxis protein
JOCLAFEN_00029 1.8e-236 mcpA NT chemotaxis protein
JOCLAFEN_00030 2.6e-219 mcpA NT chemotaxis protein
JOCLAFEN_00031 1.3e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
JOCLAFEN_00032 4.8e-41
JOCLAFEN_00033 2.8e-188 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
JOCLAFEN_00034 3.7e-75 yugU S Uncharacterised protein family UPF0047
JOCLAFEN_00035 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
JOCLAFEN_00036 3.9e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
JOCLAFEN_00037 1.9e-116 yugP S Zn-dependent protease
JOCLAFEN_00038 4.5e-18
JOCLAFEN_00039 1.1e-26 mstX S Membrane-integrating protein Mistic
JOCLAFEN_00040 1.8e-181 yugO P COG1226 Kef-type K transport systems
JOCLAFEN_00041 2.2e-72 yugN S YugN-like family
JOCLAFEN_00043 4.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
JOCLAFEN_00044 4.7e-97 S NADPH-dependent FMN reductase
JOCLAFEN_00045 4.2e-118 ycaC Q Isochorismatase family
JOCLAFEN_00046 2.8e-229 yugK C Dehydrogenase
JOCLAFEN_00047 3.8e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
JOCLAFEN_00048 1.8e-34 yuzA S Domain of unknown function (DUF378)
JOCLAFEN_00049 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
JOCLAFEN_00050 5.5e-209 yugH 2.6.1.1 E Aminotransferase
JOCLAFEN_00051 4.4e-83 alaR K Transcriptional regulator
JOCLAFEN_00052 3.2e-155 yugF I Hydrolase
JOCLAFEN_00053 1.4e-40 yugE S Domain of unknown function (DUF1871)
JOCLAFEN_00054 9.3e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
JOCLAFEN_00055 4.7e-230 T PhoQ Sensor
JOCLAFEN_00056 6.9e-68 kapB G Kinase associated protein B
JOCLAFEN_00057 4.5e-118 kapD L the KinA pathway to sporulation
JOCLAFEN_00058 1.5e-185 yuxJ EGP Major facilitator Superfamily
JOCLAFEN_00059 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
JOCLAFEN_00060 2.2e-72 yuxK S protein conserved in bacteria
JOCLAFEN_00061 9.3e-74 yufK S Family of unknown function (DUF5366)
JOCLAFEN_00062 1.5e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOCLAFEN_00063 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
JOCLAFEN_00064 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
JOCLAFEN_00065 1.6e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
JOCLAFEN_00066 4.2e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
JOCLAFEN_00067 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
JOCLAFEN_00068 3.1e-12
JOCLAFEN_00069 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
JOCLAFEN_00070 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOCLAFEN_00071 3.1e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOCLAFEN_00072 5.8e-264 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOCLAFEN_00073 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOCLAFEN_00074 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
JOCLAFEN_00075 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
JOCLAFEN_00076 2.1e-64 ydiI Q protein, possibly involved in aromatic compounds catabolism
JOCLAFEN_00077 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOCLAFEN_00078 2.5e-77 comP 2.7.13.3 T Histidine kinase
JOCLAFEN_00079 8.3e-191 comP 2.7.13.3 T Histidine kinase
JOCLAFEN_00081 1.5e-97 comQ H Belongs to the FPP GGPP synthase family
JOCLAFEN_00083 8e-52 yuzC
JOCLAFEN_00084 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
JOCLAFEN_00085 2.1e-282 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JOCLAFEN_00086 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
JOCLAFEN_00087 7.2e-68 yueI S Protein of unknown function (DUF1694)
JOCLAFEN_00088 2.8e-38 yueH S YueH-like protein
JOCLAFEN_00089 6.4e-34 yueG S Spore germination protein gerPA/gerPF
JOCLAFEN_00090 1.9e-187 yueF S transporter activity
JOCLAFEN_00091 1.6e-22 S Protein of unknown function (DUF2642)
JOCLAFEN_00092 3.7e-96 yueE S phosphohydrolase
JOCLAFEN_00093 3e-128 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_00094 6.6e-76 yueC S Family of unknown function (DUF5383)
JOCLAFEN_00095 0.0 esaA S type VII secretion protein EsaA
JOCLAFEN_00096 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
JOCLAFEN_00097 2.8e-206 essB S WXG100 protein secretion system (Wss), protein YukC
JOCLAFEN_00098 1.5e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
JOCLAFEN_00099 2.8e-45 esxA S Belongs to the WXG100 family
JOCLAFEN_00100 1.5e-228 yukF QT Transcriptional regulator
JOCLAFEN_00101 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
JOCLAFEN_00102 6.3e-133 yukJ S Uncharacterized conserved protein (DUF2278)
JOCLAFEN_00103 1.3e-34 mbtH S MbtH-like protein
JOCLAFEN_00104 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_00105 1.1e-172 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
JOCLAFEN_00106 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
JOCLAFEN_00107 2.8e-224 entC 5.4.4.2 HQ Isochorismate synthase
JOCLAFEN_00108 3.9e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOCLAFEN_00109 7.3e-166 besA S Putative esterase
JOCLAFEN_00110 1.2e-119 yuiH S Oxidoreductase molybdopterin binding domain
JOCLAFEN_00111 1.1e-101 bioY S Biotin biosynthesis protein
JOCLAFEN_00112 1.1e-208 yuiF S antiporter
JOCLAFEN_00113 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JOCLAFEN_00114 1.2e-77 yuiD S protein conserved in bacteria
JOCLAFEN_00115 1.4e-118 yuiC S protein conserved in bacteria
JOCLAFEN_00116 9.9e-28 yuiB S Putative membrane protein
JOCLAFEN_00117 7.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
JOCLAFEN_00118 1.1e-186 yumC 1.18.1.2, 1.19.1.1 C reductase
JOCLAFEN_00120 1.2e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JOCLAFEN_00121 4.8e-29
JOCLAFEN_00122 3.1e-71 CP Membrane
JOCLAFEN_00123 3.3e-124 V ABC transporter
JOCLAFEN_00125 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
JOCLAFEN_00127 6.7e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
JOCLAFEN_00128 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
JOCLAFEN_00129 1.1e-62 erpA S Belongs to the HesB IscA family
JOCLAFEN_00130 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JOCLAFEN_00131 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOCLAFEN_00132 2.4e-39 yuzB S Belongs to the UPF0349 family
JOCLAFEN_00133 3.2e-208 yutJ 1.6.99.3 C NADH dehydrogenase
JOCLAFEN_00134 4.8e-54 yuzD S protein conserved in bacteria
JOCLAFEN_00135 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
JOCLAFEN_00136 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
JOCLAFEN_00137 7.5e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JOCLAFEN_00138 3.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JOCLAFEN_00139 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
JOCLAFEN_00140 3.2e-197 yutH S Spore coat protein
JOCLAFEN_00141 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
JOCLAFEN_00142 8.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JOCLAFEN_00143 4.3e-74 yutE S Protein of unknown function DUF86
JOCLAFEN_00144 1.7e-47 yutD S protein conserved in bacteria
JOCLAFEN_00145 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JOCLAFEN_00146 1.2e-193 lytH M Peptidase, M23
JOCLAFEN_00147 5.1e-131 yunB S Sporulation protein YunB (Spo_YunB)
JOCLAFEN_00148 2.8e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JOCLAFEN_00149 1.8e-145 yunE S membrane transporter protein
JOCLAFEN_00150 2.6e-168 yunF S Protein of unknown function DUF72
JOCLAFEN_00151 1.5e-61 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
JOCLAFEN_00152 4.1e-264 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
JOCLAFEN_00153 8e-304 pucR QT COG2508 Regulator of polyketide synthase expression
JOCLAFEN_00155 1.2e-211 blt EGP Major facilitator Superfamily
JOCLAFEN_00156 4.3e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
JOCLAFEN_00157 6.2e-235 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
JOCLAFEN_00158 4.1e-169 bsn L Ribonuclease
JOCLAFEN_00159 9.8e-208 msmX P Belongs to the ABC transporter superfamily
JOCLAFEN_00160 1.8e-133 yurK K UTRA
JOCLAFEN_00161 6.9e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
JOCLAFEN_00162 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
JOCLAFEN_00163 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
JOCLAFEN_00164 3.1e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
JOCLAFEN_00165 7.9e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
JOCLAFEN_00166 1.6e-166 K helix_turn_helix, mercury resistance
JOCLAFEN_00167 4e-14
JOCLAFEN_00168 3.4e-76
JOCLAFEN_00169 2.1e-22 S Sporulation delaying protein SdpA
JOCLAFEN_00171 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
JOCLAFEN_00172 5.6e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
JOCLAFEN_00173 3.6e-123 Q ubiE/COQ5 methyltransferase family
JOCLAFEN_00174 9.4e-80 yncE S Protein of unknown function (DUF2691)
JOCLAFEN_00175 1.7e-156 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
JOCLAFEN_00176 3e-270 sufB O FeS cluster assembly
JOCLAFEN_00177 1.1e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
JOCLAFEN_00178 1.4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JOCLAFEN_00179 1.6e-244 sufD O assembly protein SufD
JOCLAFEN_00180 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
JOCLAFEN_00181 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JOCLAFEN_00182 5.1e-145 metQ P Belongs to the NlpA lipoprotein family
JOCLAFEN_00183 4.4e-94 metI P COG2011 ABC-type metal ion transport system, permease component
JOCLAFEN_00184 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JOCLAFEN_00185 5e-57 yusD S SCP-2 sterol transfer family
JOCLAFEN_00186 1.6e-54 yusE CO Thioredoxin
JOCLAFEN_00187 8.3e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
JOCLAFEN_00188 3.7e-40 yusG S Protein of unknown function (DUF2553)
JOCLAFEN_00189 3.5e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
JOCLAFEN_00190 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
JOCLAFEN_00191 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
JOCLAFEN_00192 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
JOCLAFEN_00193 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
JOCLAFEN_00194 1.3e-165 fadM E Proline dehydrogenase
JOCLAFEN_00195 1.8e-210 yusP P Major facilitator superfamily
JOCLAFEN_00196 3.9e-43
JOCLAFEN_00197 1.8e-32 yusN M Coat F domain
JOCLAFEN_00198 2.8e-68 yusO K Iron dependent repressor, N-terminal DNA binding domain
JOCLAFEN_00199 8.1e-288 yusP P Major facilitator superfamily
JOCLAFEN_00200 2.2e-157 ywbI2 K Transcriptional regulator
JOCLAFEN_00201 5.9e-140 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
JOCLAFEN_00202 1.6e-188 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOCLAFEN_00203 3.3e-39 yusU S Protein of unknown function (DUF2573)
JOCLAFEN_00204 3.1e-150 yusV 3.6.3.34 HP ABC transporter
JOCLAFEN_00205 2.5e-45 S YusW-like protein
JOCLAFEN_00206 0.0 pepF2 E COG1164 Oligoendopeptidase F
JOCLAFEN_00207 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOCLAFEN_00208 1.6e-79 dps P Belongs to the Dps family
JOCLAFEN_00209 8.3e-241 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOCLAFEN_00210 9.8e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_00211 2.3e-251 cssS 2.7.13.3 T PhoQ Sensor
JOCLAFEN_00212 3.4e-24
JOCLAFEN_00213 2.7e-158 yuxN K Transcriptional regulator
JOCLAFEN_00214 1.1e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JOCLAFEN_00215 6.6e-24 S Protein of unknown function (DUF3970)
JOCLAFEN_00216 5.5e-259 gerAA EG Spore germination protein
JOCLAFEN_00217 2e-184 gerAB E Spore germination protein
JOCLAFEN_00218 3.3e-203 gerAC S Spore germination B3/ GerAC like, C-terminal
JOCLAFEN_00219 3.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOCLAFEN_00220 2.3e-193 vraS 2.7.13.3 T Histidine kinase
JOCLAFEN_00221 6.8e-125 yvqF S Cell wall-active antibiotics response 4TMS YvqF
JOCLAFEN_00222 2.3e-127 liaG S Putative adhesin
JOCLAFEN_00223 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
JOCLAFEN_00224 3.3e-46 liaI S membrane
JOCLAFEN_00225 7.5e-228 yvqJ EGP Major facilitator Superfamily
JOCLAFEN_00226 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
JOCLAFEN_00227 4.7e-227 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
JOCLAFEN_00228 4.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_00229 1.1e-167 yvrC P ABC transporter substrate-binding protein
JOCLAFEN_00230 1.2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOCLAFEN_00231 1.3e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
JOCLAFEN_00232 0.0 T PhoQ Sensor
JOCLAFEN_00233 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_00234 1.1e-36
JOCLAFEN_00235 2.2e-102 yvrI K RNA polymerase
JOCLAFEN_00236 1.6e-15 S YvrJ protein family
JOCLAFEN_00237 9.2e-233 oxdC 4.1.1.2 G Oxalate decarboxylase
JOCLAFEN_00238 2.9e-67 yvrL S Regulatory protein YrvL
JOCLAFEN_00239 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
JOCLAFEN_00240 1.2e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_00241 5.6e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_00242 1.5e-177 fhuD P ABC transporter
JOCLAFEN_00243 1.3e-236 yvsH E Arginine ornithine antiporter
JOCLAFEN_00244 3.6e-14 S Small spore protein J (Spore_SspJ)
JOCLAFEN_00245 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
JOCLAFEN_00246 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOCLAFEN_00247 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
JOCLAFEN_00248 1.4e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
JOCLAFEN_00249 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
JOCLAFEN_00250 2.4e-113 yfiK K Regulator
JOCLAFEN_00251 8.1e-178 T Histidine kinase
JOCLAFEN_00252 5.6e-172 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
JOCLAFEN_00253 1e-193 yfiM V ABC-2 type transporter
JOCLAFEN_00254 2.4e-201 yfiN V COG0842 ABC-type multidrug transport system, permease component
JOCLAFEN_00255 1.1e-155 yvgN S reductase
JOCLAFEN_00256 3.2e-86 yvgO
JOCLAFEN_00257 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
JOCLAFEN_00258 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
JOCLAFEN_00259 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JOCLAFEN_00260 0.0 helD 3.6.4.12 L DNA helicase
JOCLAFEN_00261 3.1e-99 yvgT S membrane
JOCLAFEN_00262 5.2e-142 S Metallo-peptidase family M12
JOCLAFEN_00263 6e-73 bdbC O Required for disulfide bond formation in some proteins
JOCLAFEN_00264 4.4e-102 bdbD O Thioredoxin
JOCLAFEN_00265 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JOCLAFEN_00266 0.0 copA 3.6.3.54 P P-type ATPase
JOCLAFEN_00267 2.6e-29 copZ P Heavy-metal-associated domain
JOCLAFEN_00268 3.7e-48 csoR S transcriptional
JOCLAFEN_00269 2e-194 yvaA 1.1.1.371 S Oxidoreductase
JOCLAFEN_00270 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JOCLAFEN_00271 6.4e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOCLAFEN_00272 2.1e-45 ytnI O COG0695 Glutaredoxin and related proteins
JOCLAFEN_00273 6.4e-182 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOCLAFEN_00274 2.5e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOCLAFEN_00275 2.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
JOCLAFEN_00276 2.4e-122 tcyL P Binding-protein-dependent transport system inner membrane component
JOCLAFEN_00277 9.2e-147 tcyK M Bacterial periplasmic substrate-binding proteins
JOCLAFEN_00278 3.5e-130 ytmJ ET Bacterial periplasmic substrate-binding proteins
JOCLAFEN_00279 3e-101 ytmI K Acetyltransferase (GNAT) domain
JOCLAFEN_00280 2.7e-160 ytlI K LysR substrate binding domain
JOCLAFEN_00281 2e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOCLAFEN_00282 5.2e-50 yrdF K ribonuclease inhibitor
JOCLAFEN_00284 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JOCLAFEN_00285 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JOCLAFEN_00286 7.4e-143 est 3.1.1.1 S Carboxylesterase
JOCLAFEN_00287 4.8e-24 secG U Preprotein translocase subunit SecG
JOCLAFEN_00288 6e-35 yvzC K Transcriptional
JOCLAFEN_00289 2.3e-69 K transcriptional
JOCLAFEN_00290 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
JOCLAFEN_00291 8.8e-53 yodB K transcriptional
JOCLAFEN_00292 5.3e-259 T His Kinase A (phosphoacceptor) domain
JOCLAFEN_00293 2e-123 K Transcriptional regulatory protein, C terminal
JOCLAFEN_00294 8.8e-139 mutG S ABC-2 family transporter protein
JOCLAFEN_00295 4e-125 spaE S ABC-2 family transporter protein
JOCLAFEN_00296 4.2e-127 mutF V ABC transporter, ATP-binding protein
JOCLAFEN_00297 1.8e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOCLAFEN_00298 1.9e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JOCLAFEN_00299 1.6e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOCLAFEN_00300 5.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JOCLAFEN_00301 4.3e-76 yvbF K Belongs to the GbsR family
JOCLAFEN_00302 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOCLAFEN_00303 5.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JOCLAFEN_00304 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
JOCLAFEN_00305 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
JOCLAFEN_00306 1.9e-98 yvbF K Belongs to the GbsR family
JOCLAFEN_00307 5.2e-105 yvbG U UPF0056 membrane protein
JOCLAFEN_00308 9.9e-121 exoY M Membrane
JOCLAFEN_00309 0.0 tcaA S response to antibiotic
JOCLAFEN_00310 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
JOCLAFEN_00311 1.3e-213 EGP Major facilitator Superfamily
JOCLAFEN_00312 1.1e-177
JOCLAFEN_00313 3.7e-125 S GlcNAc-PI de-N-acetylase
JOCLAFEN_00314 2.5e-143 C WbqC-like protein family
JOCLAFEN_00315 2e-150 M Protein involved in cellulose biosynthesis
JOCLAFEN_00316 7.6e-233 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JOCLAFEN_00317 1.4e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
JOCLAFEN_00318 4.8e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
JOCLAFEN_00319 3.1e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOCLAFEN_00320 3.6e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
JOCLAFEN_00321 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JOCLAFEN_00322 8.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
JOCLAFEN_00323 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JOCLAFEN_00324 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JOCLAFEN_00325 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JOCLAFEN_00326 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JOCLAFEN_00328 7.4e-253 araE EGP Major facilitator Superfamily
JOCLAFEN_00329 1.3e-204 araR K transcriptional
JOCLAFEN_00330 6.4e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOCLAFEN_00332 2.4e-156 yvbU K Transcriptional regulator
JOCLAFEN_00333 7.7e-158 yvbV EG EamA-like transporter family
JOCLAFEN_00334 1.7e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
JOCLAFEN_00335 2.9e-259
JOCLAFEN_00336 1.4e-181 purR7 5.1.1.1 K Transcriptional regulator
JOCLAFEN_00337 6.9e-116 yyaS S Membrane
JOCLAFEN_00338 3.9e-167 3.1.3.104 S hydrolases of the HAD superfamily
JOCLAFEN_00339 1.9e-150 ybbH_1 K RpiR family transcriptional regulator
JOCLAFEN_00340 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
JOCLAFEN_00341 2.1e-225 gntP EG COG2610 H gluconate symporter and related permeases
JOCLAFEN_00342 6.1e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JOCLAFEN_00343 1.6e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
JOCLAFEN_00344 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
JOCLAFEN_00345 1.8e-223 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOCLAFEN_00346 1.3e-120 yvfI K COG2186 Transcriptional regulators
JOCLAFEN_00347 1.1e-303 yvfH C L-lactate permease
JOCLAFEN_00348 2.6e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
JOCLAFEN_00349 2.7e-32 yvfG S YvfG protein
JOCLAFEN_00350 1.4e-189 yvfF GM Exopolysaccharide biosynthesis protein
JOCLAFEN_00351 3.7e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
JOCLAFEN_00352 3.3e-54 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
JOCLAFEN_00353 9.8e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JOCLAFEN_00354 1.8e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOCLAFEN_00355 2e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
JOCLAFEN_00356 1.9e-203 epsI GM pyruvyl transferase
JOCLAFEN_00357 2.2e-193 epsH GT2 S Glycosyltransferase like family 2
JOCLAFEN_00358 1e-204 epsG S EpsG family
JOCLAFEN_00359 7.2e-214 epsF GT4 M Glycosyl transferases group 1
JOCLAFEN_00360 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOCLAFEN_00361 6.3e-218 epsD GT4 M Glycosyl transferase 4-like
JOCLAFEN_00362 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
JOCLAFEN_00363 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
JOCLAFEN_00364 1.9e-119 ywqC M biosynthesis protein
JOCLAFEN_00365 1.9e-77 slr K transcriptional
JOCLAFEN_00366 1.4e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
JOCLAFEN_00367 7.5e-97 ywjB H RibD C-terminal domain
JOCLAFEN_00368 3.7e-111 yyaS S Membrane
JOCLAFEN_00369 6.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOCLAFEN_00370 5.5e-94 padC Q Phenolic acid decarboxylase
JOCLAFEN_00371 1.1e-53 MA20_18690 S Protein of unknown function (DUF3237)
JOCLAFEN_00372 7.7e-16 S Protein of unknown function (DUF1433)
JOCLAFEN_00373 1.6e-39 S Protein of unknown function (DUF1433)
JOCLAFEN_00374 2.2e-08 I Pfam Lipase (class 3)
JOCLAFEN_00375 9.8e-18 S Protein of unknown function (DUF1433)
JOCLAFEN_00376 1.4e-231 I Pfam Lipase (class 3)
JOCLAFEN_00377 1e-37
JOCLAFEN_00378 2.9e-90 yybG S Pentapeptide repeats (8 copies)
JOCLAFEN_00379 1.9e-64 L Phage integrase family
JOCLAFEN_00381 7.4e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
JOCLAFEN_00382 1.4e-218 rafB P LacY proton/sugar symporter
JOCLAFEN_00383 3.3e-183 scrR K transcriptional
JOCLAFEN_00384 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JOCLAFEN_00385 2.6e-163 yraN K Transcriptional regulator
JOCLAFEN_00386 1.3e-215 yraM S PrpF protein
JOCLAFEN_00387 1.9e-248 EGP Sugar (and other) transporter
JOCLAFEN_00388 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
JOCLAFEN_00389 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
JOCLAFEN_00390 3.3e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
JOCLAFEN_00391 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JOCLAFEN_00392 8.6e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOCLAFEN_00393 4.6e-79 M Ribonuclease
JOCLAFEN_00394 3.7e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
JOCLAFEN_00395 4.7e-36 crh G Phosphocarrier protein Chr
JOCLAFEN_00396 3.1e-170 whiA K May be required for sporulation
JOCLAFEN_00397 1.9e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JOCLAFEN_00398 1.1e-166 rapZ S Displays ATPase and GTPase activities
JOCLAFEN_00399 2.5e-86 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JOCLAFEN_00400 3.8e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JOCLAFEN_00401 5e-124 usp CBM50 M protein conserved in bacteria
JOCLAFEN_00402 1.1e-275 S COG0457 FOG TPR repeat
JOCLAFEN_00403 3.2e-192 sasA T Histidine kinase
JOCLAFEN_00404 5e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_00405 0.0 msbA2 3.6.3.44 V ABC transporter
JOCLAFEN_00406 5.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
JOCLAFEN_00407 4.7e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
JOCLAFEN_00408 1.3e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JOCLAFEN_00409 2.1e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JOCLAFEN_00410 5.1e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
JOCLAFEN_00411 3.2e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JOCLAFEN_00412 1.3e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
JOCLAFEN_00413 3.9e-207 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JOCLAFEN_00414 2e-137 yvpB NU protein conserved in bacteria
JOCLAFEN_00415 5.4e-84 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
JOCLAFEN_00416 9.1e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
JOCLAFEN_00417 2.4e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JOCLAFEN_00418 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JOCLAFEN_00419 2.5e-225 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JOCLAFEN_00420 1.2e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JOCLAFEN_00421 4e-133 yvoA K transcriptional
JOCLAFEN_00422 4.7e-105 yxaF K Transcriptional regulator
JOCLAFEN_00423 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
JOCLAFEN_00424 3.9e-41 yvlD S Membrane
JOCLAFEN_00425 9.6e-26 pspB KT PspC domain
JOCLAFEN_00426 3.2e-166 yvlB S Putative adhesin
JOCLAFEN_00427 6.1e-49 yvlA
JOCLAFEN_00428 3e-38 yvkN
JOCLAFEN_00429 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JOCLAFEN_00430 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JOCLAFEN_00431 7.6e-33 csbA S protein conserved in bacteria
JOCLAFEN_00432 0.0 yvkC 2.7.9.2 GT Phosphotransferase
JOCLAFEN_00433 2.4e-110 yvkB K Transcriptional regulator
JOCLAFEN_00434 3e-227 yvkA EGP Major facilitator Superfamily
JOCLAFEN_00435 1e-26 bacT Q Thioesterase domain
JOCLAFEN_00437 1e-177 S Psort location CytoplasmicMembrane, score
JOCLAFEN_00438 9.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOCLAFEN_00439 1.5e-55 swrA S Swarming motility protein
JOCLAFEN_00440 2.5e-253 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
JOCLAFEN_00441 3.3e-224 ywoF P Right handed beta helix region
JOCLAFEN_00442 1.7e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
JOCLAFEN_00443 1e-122 ftsE D cell division ATP-binding protein FtsE
JOCLAFEN_00444 2.4e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
JOCLAFEN_00445 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
JOCLAFEN_00446 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JOCLAFEN_00447 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JOCLAFEN_00448 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JOCLAFEN_00449 6.8e-68
JOCLAFEN_00450 9.1e-11 fliT S bacterial-type flagellum organization
JOCLAFEN_00451 3e-66 fliS N flagellar protein FliS
JOCLAFEN_00452 4e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JOCLAFEN_00453 7.1e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JOCLAFEN_00454 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
JOCLAFEN_00455 3.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
JOCLAFEN_00456 1.4e-80 yviE
JOCLAFEN_00457 6.1e-163 flgL N Belongs to the bacterial flagellin family
JOCLAFEN_00458 8.2e-274 flgK N flagellar hook-associated protein
JOCLAFEN_00459 8.9e-81 flgN NOU FlgN protein
JOCLAFEN_00460 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
JOCLAFEN_00461 2.4e-74 yvyF S flagellar protein
JOCLAFEN_00462 1.3e-67 comFC S Phosphoribosyl transferase domain
JOCLAFEN_00463 1.5e-43 comFB S Late competence development protein ComFB
JOCLAFEN_00464 8.1e-260 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
JOCLAFEN_00465 1.6e-157 degV S protein conserved in bacteria
JOCLAFEN_00466 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOCLAFEN_00467 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
JOCLAFEN_00468 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
JOCLAFEN_00469 1.1e-172 yvhJ K Transcriptional regulator
JOCLAFEN_00470 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
JOCLAFEN_00471 6.1e-240 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
JOCLAFEN_00472 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
JOCLAFEN_00473 1.6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
JOCLAFEN_00474 3.8e-257 tuaE M Teichuronic acid biosynthesis protein
JOCLAFEN_00475 6.6e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOCLAFEN_00476 7.3e-225 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
JOCLAFEN_00477 1e-257 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOCLAFEN_00478 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
JOCLAFEN_00479 9.3e-270 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOCLAFEN_00480 0.0 lytB 3.5.1.28 D Stage II sporulation protein
JOCLAFEN_00481 5.9e-49
JOCLAFEN_00482 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
JOCLAFEN_00483 8.8e-212 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JOCLAFEN_00484 6.3e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOCLAFEN_00485 2.6e-283 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JOCLAFEN_00486 1.7e-151 tagG GM Transport permease protein
JOCLAFEN_00487 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOCLAFEN_00488 3.3e-294 M Glycosyltransferase like family 2
JOCLAFEN_00489 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
JOCLAFEN_00490 1.7e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JOCLAFEN_00491 4e-220 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
JOCLAFEN_00492 1.9e-241 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JOCLAFEN_00493 9.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
JOCLAFEN_00494 1.3e-265 gerBA EG Spore germination protein
JOCLAFEN_00495 6.4e-199 gerBB E Spore germination protein
JOCLAFEN_00496 3.2e-214 gerAC S Spore germination protein
JOCLAFEN_00497 4e-267 GT2,GT4 J Glycosyl transferase family 2
JOCLAFEN_00498 8.3e-249 ywtG EGP Major facilitator Superfamily
JOCLAFEN_00499 3.8e-179 ywtF K Transcriptional regulator
JOCLAFEN_00500 4.2e-158 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
JOCLAFEN_00501 3.5e-36 yttA 2.7.13.3 S Pfam Transposase IS66
JOCLAFEN_00502 7.5e-241 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JOCLAFEN_00503 1.3e-20 ywtC
JOCLAFEN_00504 1.2e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
JOCLAFEN_00505 2.3e-70 pgsC S biosynthesis protein
JOCLAFEN_00506 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
JOCLAFEN_00507 1.7e-183 gerKA EG Spore germination protein
JOCLAFEN_00508 1.7e-191 gerKB E Spore germination protein
JOCLAFEN_00509 1.4e-201 gerKC S Spore germination B3/ GerAC like, C-terminal
JOCLAFEN_00510 1.1e-178 rbsR K transcriptional
JOCLAFEN_00511 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOCLAFEN_00512 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JOCLAFEN_00513 1.3e-279 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
JOCLAFEN_00514 3.2e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
JOCLAFEN_00515 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
JOCLAFEN_00516 5.2e-90 batE T Sh3 type 3 domain protein
JOCLAFEN_00517 2.8e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
JOCLAFEN_00518 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
JOCLAFEN_00519 1.2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JOCLAFEN_00520 9e-167 alsR K LysR substrate binding domain
JOCLAFEN_00522 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JOCLAFEN_00523 4.4e-126 ywrJ
JOCLAFEN_00524 1.6e-128 cotB
JOCLAFEN_00525 3.8e-212 cotH M Spore Coat
JOCLAFEN_00526 2.2e-09
JOCLAFEN_00527 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JOCLAFEN_00529 3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JOCLAFEN_00530 1.1e-83 ywrC K Transcriptional regulator
JOCLAFEN_00531 1.2e-103 ywrB P Chromate transporter
JOCLAFEN_00532 1.7e-88 ywrA P COG2059 Chromate transport protein ChrA
JOCLAFEN_00533 4.9e-128 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
JOCLAFEN_00534 8.7e-25
JOCLAFEN_00535 5.1e-241 ywqJ S Pre-toxin TG
JOCLAFEN_00536 4.3e-37 ywqI S Family of unknown function (DUF5344)
JOCLAFEN_00537 7.2e-21 S Domain of unknown function (DUF5082)
JOCLAFEN_00539 1.5e-149 ywqG S Domain of unknown function (DUF1963)
JOCLAFEN_00540 3.6e-249 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
JOCLAFEN_00541 1.6e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
JOCLAFEN_00542 1.5e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
JOCLAFEN_00543 3e-54 ywqC M biosynthesis protein
JOCLAFEN_00544 9.1e-44 ywqC M biosynthesis protein
JOCLAFEN_00545 1.3e-14
JOCLAFEN_00546 4.6e-307 ywqB S SWIM zinc finger
JOCLAFEN_00547 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JOCLAFEN_00548 2e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
JOCLAFEN_00549 5.4e-136 glcR K DeoR C terminal sensor domain
JOCLAFEN_00550 1.7e-57 ssbB L Single-stranded DNA-binding protein
JOCLAFEN_00551 4e-62 ywpG
JOCLAFEN_00552 1.9e-68 ywpF S YwpF-like protein
JOCLAFEN_00553 1.1e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JOCLAFEN_00554 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JOCLAFEN_00555 7.2e-200 S aspartate phosphatase
JOCLAFEN_00556 1e-145 flhP N flagellar basal body
JOCLAFEN_00557 3.2e-128 flhO N flagellar basal body
JOCLAFEN_00558 2.7e-180 mbl D Rod shape-determining protein
JOCLAFEN_00559 1.8e-44 spoIIID K Stage III sporulation protein D
JOCLAFEN_00560 8.5e-72 ywoH K transcriptional
JOCLAFEN_00561 8.4e-213 ywoG EGP Major facilitator Superfamily
JOCLAFEN_00562 9.3e-275 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
JOCLAFEN_00563 5.2e-243 ywoD EGP Major facilitator superfamily
JOCLAFEN_00564 2e-100 phzA Q Isochorismatase family
JOCLAFEN_00565 2.5e-228 amt P Ammonium transporter
JOCLAFEN_00566 2e-58 nrgB K Belongs to the P(II) protein family
JOCLAFEN_00567 2.4e-209 ftsW D Belongs to the SEDS family
JOCLAFEN_00568 4.2e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
JOCLAFEN_00569 5.6e-71 ywnJ S VanZ like family
JOCLAFEN_00570 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
JOCLAFEN_00571 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
JOCLAFEN_00572 1.2e-10 ywnC S Family of unknown function (DUF5362)
JOCLAFEN_00573 1.6e-68 ywnF S Family of unknown function (DUF5392)
JOCLAFEN_00574 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOCLAFEN_00575 4.8e-53 ywnC S Family of unknown function (DUF5362)
JOCLAFEN_00576 3.4e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
JOCLAFEN_00578 6.1e-67 ywnA K Transcriptional regulator
JOCLAFEN_00579 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
JOCLAFEN_00580 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
JOCLAFEN_00581 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
JOCLAFEN_00583 8e-82 ywmF S Peptidase M50
JOCLAFEN_00584 1.6e-93 S response regulator aspartate phosphatase
JOCLAFEN_00585 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JOCLAFEN_00586 1.1e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JOCLAFEN_00588 7.8e-123 ywmD S protein containing a von Willebrand factor type A (vWA) domain
JOCLAFEN_00589 1.6e-115 ywmC S protein containing a von Willebrand factor type A (vWA) domain
JOCLAFEN_00590 9.5e-189 spoIID D Stage II sporulation protein D
JOCLAFEN_00591 1.4e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOCLAFEN_00592 3.1e-133 ywmB S TATA-box binding
JOCLAFEN_00593 1.3e-32 ywzB S membrane
JOCLAFEN_00594 1.2e-90 ywmA
JOCLAFEN_00595 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JOCLAFEN_00596 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JOCLAFEN_00597 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JOCLAFEN_00598 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JOCLAFEN_00599 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOCLAFEN_00600 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JOCLAFEN_00601 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOCLAFEN_00602 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
JOCLAFEN_00603 2.1e-61 atpI S ATP synthase
JOCLAFEN_00604 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JOCLAFEN_00605 8.7e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JOCLAFEN_00606 1.1e-95 ywlG S Belongs to the UPF0340 family
JOCLAFEN_00607 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
JOCLAFEN_00608 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOCLAFEN_00609 9e-85 mntP P Probably functions as a manganese efflux pump
JOCLAFEN_00610 1e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JOCLAFEN_00611 1.8e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
JOCLAFEN_00612 8.9e-119 spoIIR S stage II sporulation protein R
JOCLAFEN_00613 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
JOCLAFEN_00615 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JOCLAFEN_00616 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JOCLAFEN_00617 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOCLAFEN_00618 1.5e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
JOCLAFEN_00619 3.6e-158 ywkB S Membrane transport protein
JOCLAFEN_00620 0.0 sfcA 1.1.1.38 C malic enzyme
JOCLAFEN_00621 1.4e-104 tdk 2.7.1.21 F thymidine kinase
JOCLAFEN_00622 1.1e-32 rpmE J Binds the 23S rRNA
JOCLAFEN_00623 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JOCLAFEN_00624 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
JOCLAFEN_00625 1.5e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOCLAFEN_00626 6.4e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JOCLAFEN_00627 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
JOCLAFEN_00628 3.2e-62 spo0F T COG0784 FOG CheY-like receiver
JOCLAFEN_00629 1.7e-93 ywjG S Domain of unknown function (DUF2529)
JOCLAFEN_00630 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JOCLAFEN_00631 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JOCLAFEN_00632 0.0 fadF C COG0247 Fe-S oxidoreductase
JOCLAFEN_00633 1.7e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
JOCLAFEN_00634 7.5e-180 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
JOCLAFEN_00635 4.2e-43 ywjC
JOCLAFEN_00636 0.0 ywjA V ABC transporter
JOCLAFEN_00637 1.3e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOCLAFEN_00638 2.6e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOCLAFEN_00639 5.9e-123 narI 1.7.5.1 C nitrate reductase, gamma
JOCLAFEN_00640 5.1e-96 narJ 1.7.5.1 C nitrate reductase
JOCLAFEN_00641 4.5e-293 narH 1.7.5.1 C Nitrate reductase, beta
JOCLAFEN_00642 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOCLAFEN_00643 2e-85 arfM T cyclic nucleotide binding
JOCLAFEN_00644 1.5e-137 ywiC S YwiC-like protein
JOCLAFEN_00645 9.4e-127 fnr K helix_turn_helix, cAMP Regulatory protein
JOCLAFEN_00646 5.8e-214 narK P COG2223 Nitrate nitrite transporter
JOCLAFEN_00647 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JOCLAFEN_00648 1.2e-73 ywiB S protein conserved in bacteria
JOCLAFEN_00650 2.3e-230 ywhL CO amine dehydrogenase activity
JOCLAFEN_00651 1.7e-198 ywhK CO amine dehydrogenase activity
JOCLAFEN_00652 1.9e-76 S aspartate phosphatase
JOCLAFEN_00654 2.6e-29 ydcG K sequence-specific DNA binding
JOCLAFEN_00655 5e-33
JOCLAFEN_00656 2e-28 S Domain of unknown function (DUF4177)
JOCLAFEN_00658 6.2e-77 CP Membrane
JOCLAFEN_00661 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
JOCLAFEN_00662 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JOCLAFEN_00663 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JOCLAFEN_00664 7.2e-82
JOCLAFEN_00665 1.4e-95 ywhD S YwhD family
JOCLAFEN_00666 1.2e-117 ywhC S Peptidase family M50
JOCLAFEN_00667 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
JOCLAFEN_00668 5.2e-69 ywhA K Transcriptional regulator
JOCLAFEN_00669 1.3e-246 yhdG_1 E C-terminus of AA_permease
JOCLAFEN_00670 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
JOCLAFEN_00671 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
JOCLAFEN_00672 6.9e-36 ywzC S Belongs to the UPF0741 family
JOCLAFEN_00673 6.6e-110 rsfA_1
JOCLAFEN_00674 4.1e-50 padR K PadR family transcriptional regulator
JOCLAFEN_00675 8.1e-94 S membrane
JOCLAFEN_00676 7.7e-166 V ABC transporter, ATP-binding protein
JOCLAFEN_00677 2.9e-168 yhcI S ABC transporter (permease)
JOCLAFEN_00680 2.1e-179
JOCLAFEN_00682 7.7e-160 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
JOCLAFEN_00683 3e-162 cysL K Transcriptional regulator
JOCLAFEN_00684 1.9e-159 MA20_14895 S Conserved hypothetical protein 698
JOCLAFEN_00685 1.1e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
JOCLAFEN_00686 4.3e-146 ywfI C May function as heme-dependent peroxidase
JOCLAFEN_00687 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
JOCLAFEN_00688 2.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
JOCLAFEN_00689 6.1e-208 bacE EGP Major facilitator Superfamily
JOCLAFEN_00690 4.4e-269 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
JOCLAFEN_00691 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_00692 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
JOCLAFEN_00693 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
JOCLAFEN_00694 3.2e-223 ywfA EGP Major facilitator Superfamily
JOCLAFEN_00695 1.9e-204 tcaB EGP Major facilitator Superfamily
JOCLAFEN_00696 8.3e-260 lysP E amino acid
JOCLAFEN_00697 0.0 rocB E arginine degradation protein
JOCLAFEN_00698 3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JOCLAFEN_00699 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOCLAFEN_00700 3.2e-59
JOCLAFEN_00701 7.9e-87 spsL 5.1.3.13 M Spore Coat
JOCLAFEN_00702 8.1e-162 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
JOCLAFEN_00703 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
JOCLAFEN_00704 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
JOCLAFEN_00705 4.7e-185 spsG M Spore Coat
JOCLAFEN_00706 2.8e-134 spsF M Spore Coat
JOCLAFEN_00707 1.6e-213 spsE 2.5.1.56 M acid synthase
JOCLAFEN_00708 2e-160 spsD 2.3.1.210 K Spore Coat
JOCLAFEN_00709 3.3e-222 spsC E Belongs to the DegT DnrJ EryC1 family
JOCLAFEN_00710 2.7e-274 spsB M Capsule polysaccharide biosynthesis protein
JOCLAFEN_00711 3.4e-143 spsA M Spore Coat
JOCLAFEN_00712 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
JOCLAFEN_00713 1.6e-45 ywdK S small membrane protein
JOCLAFEN_00714 7.5e-231 ywdJ F Xanthine uracil
JOCLAFEN_00715 4.7e-41 ywdI S Family of unknown function (DUF5327)
JOCLAFEN_00716 1.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JOCLAFEN_00717 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
JOCLAFEN_00719 1.5e-88 ywdD
JOCLAFEN_00720 6.3e-57 pex K Transcriptional regulator PadR-like family
JOCLAFEN_00721 1e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOCLAFEN_00722 9.7e-20 ywdA
JOCLAFEN_00723 8.6e-289 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
JOCLAFEN_00724 1.1e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOCLAFEN_00725 2e-07 sacT K transcriptional antiterminator
JOCLAFEN_00726 8.3e-151 sacT K transcriptional antiterminator
JOCLAFEN_00728 0.0 vpr O Belongs to the peptidase S8 family
JOCLAFEN_00729 3.1e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOCLAFEN_00730 3e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
JOCLAFEN_00731 2.8e-208 rodA D Belongs to the SEDS family
JOCLAFEN_00732 3.7e-80 ysnE K acetyltransferase
JOCLAFEN_00733 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
JOCLAFEN_00734 6.4e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JOCLAFEN_00735 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
JOCLAFEN_00736 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOCLAFEN_00737 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
JOCLAFEN_00738 8.4e-27 ywzA S membrane
JOCLAFEN_00739 3e-295 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JOCLAFEN_00740 2e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JOCLAFEN_00741 1.7e-61 gtcA S GtrA-like protein
JOCLAFEN_00742 1.1e-110 ywcC K Bacterial regulatory proteins, tetR family
JOCLAFEN_00744 4.3e-129 H Methionine biosynthesis protein MetW
JOCLAFEN_00745 3.7e-133 S Streptomycin biosynthesis protein StrF
JOCLAFEN_00746 4.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JOCLAFEN_00747 8.4e-240 ywbN P Dyp-type peroxidase family protein
JOCLAFEN_00748 1.9e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JOCLAFEN_00749 1.3e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JOCLAFEN_00750 8.2e-152 ywbI K Transcriptional regulator
JOCLAFEN_00751 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
JOCLAFEN_00752 1.3e-109 ywbG M effector of murein hydrolase
JOCLAFEN_00753 1e-95 V ATPases associated with a variety of cellular activities
JOCLAFEN_00756 1.3e-105
JOCLAFEN_00758 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
JOCLAFEN_00759 3.8e-79 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
JOCLAFEN_00760 6.4e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
JOCLAFEN_00761 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JOCLAFEN_00762 1.1e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
JOCLAFEN_00763 2.9e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
JOCLAFEN_00764 9.2e-179 cysP P phosphate transporter
JOCLAFEN_00765 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
JOCLAFEN_00767 1.9e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JOCLAFEN_00768 9.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JOCLAFEN_00769 3e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
JOCLAFEN_00770 1.3e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
JOCLAFEN_00771 0.0 carB 6.3.5.5 F Belongs to the CarB family
JOCLAFEN_00772 1.2e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JOCLAFEN_00773 5e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
JOCLAFEN_00774 8.2e-168 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
JOCLAFEN_00775 8e-233 pyrP F Xanthine uracil
JOCLAFEN_00776 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JOCLAFEN_00777 1.8e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOCLAFEN_00778 1.2e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JOCLAFEN_00779 3.4e-64 dksA T COG1734 DnaK suppressor protein
JOCLAFEN_00780 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JOCLAFEN_00781 8.9e-68 divIVA D Cell division initiation protein
JOCLAFEN_00782 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
JOCLAFEN_00783 5.2e-41 yggT S membrane
JOCLAFEN_00784 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JOCLAFEN_00785 2.5e-124 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JOCLAFEN_00786 5.7e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
JOCLAFEN_00787 2.2e-38 ylmC S sporulation protein
JOCLAFEN_00788 1.7e-256 argE 3.5.1.16 E Acetylornithine deacetylase
JOCLAFEN_00789 2.9e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
JOCLAFEN_00790 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOCLAFEN_00791 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOCLAFEN_00792 1.9e-159 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
JOCLAFEN_00793 0.0 bpr O COG1404 Subtilisin-like serine proteases
JOCLAFEN_00794 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JOCLAFEN_00795 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JOCLAFEN_00796 8.7e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JOCLAFEN_00797 5.6e-169 murB 1.3.1.98 M cell wall formation
JOCLAFEN_00798 1.8e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JOCLAFEN_00799 2.2e-185 spoVE D Belongs to the SEDS family
JOCLAFEN_00800 3.4e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JOCLAFEN_00801 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JOCLAFEN_00802 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JOCLAFEN_00803 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
JOCLAFEN_00804 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JOCLAFEN_00805 2.9e-52 ftsL D Essential cell division protein
JOCLAFEN_00806 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JOCLAFEN_00807 8.9e-78 mraZ K Belongs to the MraZ family
JOCLAFEN_00808 9.3e-311 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JOCLAFEN_00809 8e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOCLAFEN_00810 8.1e-90 ylbP K n-acetyltransferase
JOCLAFEN_00811 3.8e-70 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
JOCLAFEN_00812 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JOCLAFEN_00813 7.8e-91 yceD S metal-binding, possibly nucleic acid-binding protein
JOCLAFEN_00814 6e-230 ylbM S Belongs to the UPF0348 family
JOCLAFEN_00815 3e-187 ylbL T Belongs to the peptidase S16 family
JOCLAFEN_00816 8.9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
JOCLAFEN_00817 2.2e-216 ylbJ S Sporulation integral membrane protein YlbJ
JOCLAFEN_00818 1.1e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JOCLAFEN_00819 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
JOCLAFEN_00821 7.2e-43 ylbG S UPF0298 protein
JOCLAFEN_00822 1.2e-71 ylbF S Belongs to the UPF0342 family
JOCLAFEN_00823 8.8e-37 ylbE S YlbE-like protein
JOCLAFEN_00824 6.5e-56 ylbD S Putative coat protein
JOCLAFEN_00825 2.1e-199 ylbC S protein with SCP PR1 domains
JOCLAFEN_00826 4.8e-73 ylbB T COG0517 FOG CBS domain
JOCLAFEN_00827 8.5e-60 ylbA S YugN-like family
JOCLAFEN_00828 9.7e-166 ctaG S cytochrome c oxidase
JOCLAFEN_00829 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
JOCLAFEN_00830 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
JOCLAFEN_00831 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JOCLAFEN_00832 1.4e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
JOCLAFEN_00833 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JOCLAFEN_00834 2.9e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
JOCLAFEN_00835 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
JOCLAFEN_00836 3.2e-212 ftsW D Belongs to the SEDS family
JOCLAFEN_00837 8.7e-44 ylaN S Belongs to the UPF0358 family
JOCLAFEN_00838 7e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
JOCLAFEN_00839 3.8e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JOCLAFEN_00840 2.2e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
JOCLAFEN_00841 2.3e-105 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOCLAFEN_00842 1.5e-32 ylaI S protein conserved in bacteria
JOCLAFEN_00843 1.3e-48 ylaH S YlaH-like protein
JOCLAFEN_00844 0.0 typA T GTP-binding protein TypA
JOCLAFEN_00845 6.7e-24 S Family of unknown function (DUF5325)
JOCLAFEN_00846 7e-38 ylaE
JOCLAFEN_00847 3.1e-12 sigC S Putative zinc-finger
JOCLAFEN_00848 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
JOCLAFEN_00849 1.8e-83 ykzC S Acetyltransferase (GNAT) family
JOCLAFEN_00850 2.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
JOCLAFEN_00851 6.3e-24 ykzI
JOCLAFEN_00852 4.9e-119 yktB S Belongs to the UPF0637 family
JOCLAFEN_00853 1.6e-42 yktA S Belongs to the UPF0223 family
JOCLAFEN_00854 3.8e-276 speA 4.1.1.19 E Arginine
JOCLAFEN_00855 3.7e-140 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
JOCLAFEN_00856 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
JOCLAFEN_00857 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOCLAFEN_00858 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOCLAFEN_00859 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOCLAFEN_00860 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOCLAFEN_00861 4.9e-212 V Beta-lactamase
JOCLAFEN_00862 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
JOCLAFEN_00863 0.0 Q Polyketide synthase of type I
JOCLAFEN_00864 0.0 Q Polyketide synthase of type I
JOCLAFEN_00865 0.0 Q Polyketide synthase of type I
JOCLAFEN_00866 0.0 Q Polyketide synthase of type I
JOCLAFEN_00867 0.0 Q polyketide synthase
JOCLAFEN_00868 0.0 Q Polyketide synthase of type I
JOCLAFEN_00869 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOCLAFEN_00870 5.9e-104 recN L Putative cell-wall binding lipoprotein
JOCLAFEN_00872 4.4e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JOCLAFEN_00873 8e-148 ykrA S hydrolases of the HAD superfamily
JOCLAFEN_00874 8.2e-31 ykzG S Belongs to the UPF0356 family
JOCLAFEN_00875 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOCLAFEN_00876 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JOCLAFEN_00877 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
JOCLAFEN_00878 4.1e-150 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
JOCLAFEN_00879 1.1e-245 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOCLAFEN_00880 2.1e-45 abrB K of stationary sporulation gene expression
JOCLAFEN_00881 6.9e-184 mreB D Rod-share determining protein MreBH
JOCLAFEN_00882 5.5e-12 S Uncharacterized protein YkpC
JOCLAFEN_00883 5e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
JOCLAFEN_00884 3.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOCLAFEN_00885 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOCLAFEN_00886 3.4e-37 ykoA
JOCLAFEN_00887 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOCLAFEN_00888 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
JOCLAFEN_00889 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
JOCLAFEN_00890 1.2e-132 fruR K Transcriptional regulator
JOCLAFEN_00891 3.2e-212 yknZ V ABC transporter (permease)
JOCLAFEN_00892 6.1e-123 macB V ABC transporter, ATP-binding protein
JOCLAFEN_00893 1.4e-172 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JOCLAFEN_00894 6.4e-104 yknW S Yip1 domain
JOCLAFEN_00895 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JOCLAFEN_00896 3.5e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
JOCLAFEN_00897 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
JOCLAFEN_00898 1.9e-242 moeA 2.10.1.1 H molybdopterin
JOCLAFEN_00899 1.1e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JOCLAFEN_00900 2.2e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
JOCLAFEN_00901 8.6e-163 yknT
JOCLAFEN_00902 1.5e-98 rok K Repressor of ComK
JOCLAFEN_00903 7.9e-79 ykuV CO thiol-disulfide
JOCLAFEN_00904 1.1e-139 ykuT M Mechanosensitive ion channel
JOCLAFEN_00905 4.8e-38 ykuS S Belongs to the UPF0180 family
JOCLAFEN_00906 2.6e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
JOCLAFEN_00907 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
JOCLAFEN_00908 2.3e-78 fld C Flavodoxin
JOCLAFEN_00909 3.6e-168 ykuO
JOCLAFEN_00910 6.1e-90 fld C Flavodoxin
JOCLAFEN_00911 4.6e-168 ccpC K Transcriptional regulator
JOCLAFEN_00912 1e-75 ykuL S CBS domain
JOCLAFEN_00913 2.5e-26 ykzF S Antirepressor AbbA
JOCLAFEN_00914 8.4e-93 ykuK S Ribonuclease H-like
JOCLAFEN_00915 3.9e-37 ykuJ S protein conserved in bacteria
JOCLAFEN_00916 4.3e-233 ykuI T Diguanylate phosphodiesterase
JOCLAFEN_00918 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_00919 3e-156 ykuE S Metallophosphoesterase
JOCLAFEN_00920 1.2e-88 ykuD S protein conserved in bacteria
JOCLAFEN_00921 3e-240 ykuC EGP Major facilitator Superfamily
JOCLAFEN_00922 1.4e-83 ykyB S YkyB-like protein
JOCLAFEN_00923 1.8e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
JOCLAFEN_00924 2.3e-09
JOCLAFEN_00925 3.9e-215 patA 2.6.1.1 E Aminotransferase
JOCLAFEN_00926 6.8e-291 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
JOCLAFEN_00927 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
JOCLAFEN_00928 2.8e-92 ykwD J protein with SCP PR1 domains
JOCLAFEN_00929 5.6e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
JOCLAFEN_00930 7.7e-264 mcpC NT chemotaxis protein
JOCLAFEN_00931 7.2e-189 splB 4.1.99.14 L Spore photoproduct lyase
JOCLAFEN_00932 6.1e-38 splA S Transcriptional regulator
JOCLAFEN_00933 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOCLAFEN_00934 2.1e-39 ptsH G phosphocarrier protein HPr
JOCLAFEN_00935 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOCLAFEN_00936 5.1e-156 glcT K antiterminator
JOCLAFEN_00937 1e-176 ykvZ 5.1.1.1 K Transcriptional regulator
JOCLAFEN_00939 5.9e-205 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JOCLAFEN_00940 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
JOCLAFEN_00941 2.7e-88 stoA CO thiol-disulfide
JOCLAFEN_00942 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOCLAFEN_00943 6.3e-111 ykvT 3.5.1.28 M Cell Wall Hydrolase
JOCLAFEN_00944 2.3e-27
JOCLAFEN_00945 7.8e-25 ykvS S protein conserved in bacteria
JOCLAFEN_00946 1.3e-44 ykvR S Protein of unknown function (DUF3219)
JOCLAFEN_00948 2e-161 G Glycosyl hydrolases family 18
JOCLAFEN_00949 2.3e-34 3.5.1.104 M LysM domain
JOCLAFEN_00950 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
JOCLAFEN_00951 1.4e-32 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JOCLAFEN_00952 1.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
JOCLAFEN_00953 6.4e-60 ykvN K HxlR-like helix-turn-helix
JOCLAFEN_00955 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JOCLAFEN_00956 1.9e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
JOCLAFEN_00957 1.3e-78 queD 4.1.2.50, 4.2.3.12 H synthase
JOCLAFEN_00958 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JOCLAFEN_00959 3.9e-188
JOCLAFEN_00960 4.1e-184 ykvI S membrane
JOCLAFEN_00961 0.0 clpE O Belongs to the ClpA ClpB family
JOCLAFEN_00962 1.1e-136 motA N flagellar motor
JOCLAFEN_00963 7.9e-127 motB N Flagellar motor protein
JOCLAFEN_00964 1.5e-77 ykvE K transcriptional
JOCLAFEN_00965 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOCLAFEN_00966 2.6e-10 S Spo0E like sporulation regulatory protein
JOCLAFEN_00967 3.8e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
JOCLAFEN_00968 2.2e-116 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
JOCLAFEN_00969 4.4e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
JOCLAFEN_00970 6.1e-227 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
JOCLAFEN_00971 3.7e-229 mtnE 2.6.1.83 E Aminotransferase
JOCLAFEN_00972 6.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JOCLAFEN_00973 1.9e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
JOCLAFEN_00974 5.3e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JOCLAFEN_00976 1.3e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOCLAFEN_00977 0.0 kinE 2.7.13.3 T Histidine kinase
JOCLAFEN_00978 4.2e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
JOCLAFEN_00979 7.9e-24 ykzE
JOCLAFEN_00980 1.1e-113 ydfR S Protein of unknown function (DUF421)
JOCLAFEN_00981 1.3e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
JOCLAFEN_00982 4.1e-156 htpX O Belongs to the peptidase M48B family
JOCLAFEN_00983 7.8e-126 ykrK S Domain of unknown function (DUF1836)
JOCLAFEN_00984 2.5e-26 sspD S small acid-soluble spore protein
JOCLAFEN_00985 3.1e-119 rsgI S Anti-sigma factor N-terminus
JOCLAFEN_00986 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOCLAFEN_00987 1.2e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
JOCLAFEN_00988 4.1e-101 ykoX S membrane-associated protein
JOCLAFEN_00989 4.2e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
JOCLAFEN_00990 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
JOCLAFEN_00991 3.7e-99 ykoP G polysaccharide deacetylase
JOCLAFEN_00992 5e-81 ykoM K transcriptional
JOCLAFEN_00993 2e-25 ykoL
JOCLAFEN_00994 1.9e-16
JOCLAFEN_00995 5.4e-53 tnrA K transcriptional
JOCLAFEN_00996 5e-238 mgtE P Acts as a magnesium transporter
JOCLAFEN_00998 1e-245 ydhD M Glycosyl hydrolase
JOCLAFEN_00999 2e-98 ykoE S ABC-type cobalt transport system, permease component
JOCLAFEN_01000 2.2e-304 P ABC transporter, ATP-binding protein
JOCLAFEN_01001 1e-131 ykoC P Cobalt transport protein
JOCLAFEN_01002 1.2e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOCLAFEN_01003 2.9e-176 isp O Belongs to the peptidase S8 family
JOCLAFEN_01004 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JOCLAFEN_01005 4e-119 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
JOCLAFEN_01006 2.7e-216 hcaT 1.5.1.2 EGP Major facilitator Superfamily
JOCLAFEN_01007 1.4e-126 M PFAM Collagen triple helix repeat (20 copies)
JOCLAFEN_01008 5.8e-216 M Glycosyl transferase family 2
JOCLAFEN_01010 8.9e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JOCLAFEN_01011 4.2e-71 ohrB O Organic hydroperoxide resistance protein
JOCLAFEN_01012 6.1e-88 ohrR K COG1846 Transcriptional regulators
JOCLAFEN_01013 1.3e-70 ohrA O Organic hydroperoxide resistance protein
JOCLAFEN_01014 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JOCLAFEN_01015 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOCLAFEN_01016 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
JOCLAFEN_01017 3.4e-49 ykkD P Multidrug resistance protein
JOCLAFEN_01018 9.4e-53 ykkC P Multidrug resistance protein
JOCLAFEN_01019 6.1e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JOCLAFEN_01020 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
JOCLAFEN_01021 5.9e-160 ykgA E Amidinotransferase
JOCLAFEN_01022 2.5e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
JOCLAFEN_01023 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
JOCLAFEN_01024 1.6e-171 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
JOCLAFEN_01025 1.8e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
JOCLAFEN_01026 6.4e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
JOCLAFEN_01027 0.0 dppE E ABC transporter substrate-binding protein
JOCLAFEN_01028 8.5e-190 dppD P Belongs to the ABC transporter superfamily
JOCLAFEN_01029 5e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOCLAFEN_01030 1.4e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOCLAFEN_01031 6.5e-156 dppA E D-aminopeptidase
JOCLAFEN_01033 6.9e-284 yubD P Major Facilitator Superfamily
JOCLAFEN_01034 1.6e-204 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOCLAFEN_01036 3.4e-180 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOCLAFEN_01037 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOCLAFEN_01038 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
JOCLAFEN_01039 1.5e-242 steT E amino acid
JOCLAFEN_01040 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
JOCLAFEN_01041 7.5e-175 pit P phosphate transporter
JOCLAFEN_01042 6.3e-134 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
JOCLAFEN_01043 8.7e-23 spoIISB S Stage II sporulation protein SB
JOCLAFEN_01044 1.9e-169 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOCLAFEN_01045 2.3e-38 xhlB S SPP1 phage holin
JOCLAFEN_01046 2.5e-37 xhlA S Haemolysin XhlA
JOCLAFEN_01047 4.8e-137 xepA
JOCLAFEN_01048 6.5e-30 xkdX
JOCLAFEN_01050 2.9e-91
JOCLAFEN_01051 1.2e-26
JOCLAFEN_01052 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
JOCLAFEN_01053 1.3e-164 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
JOCLAFEN_01054 7.2e-58 xkdS S Protein of unknown function (DUF2634)
JOCLAFEN_01055 7.2e-32 xkdR S Protein of unknown function (DUF2577)
JOCLAFEN_01056 6.1e-161 xkdQ 3.2.1.96 G NLP P60 protein
JOCLAFEN_01057 6.2e-109 xkdP S Lysin motif
JOCLAFEN_01058 1.3e-182 xkdO L Transglycosylase SLT domain
JOCLAFEN_01059 3.4e-19
JOCLAFEN_01060 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
JOCLAFEN_01061 2e-74 xkdM S Phage tail tube protein
JOCLAFEN_01062 2.2e-225 xkdK S Phage tail sheath C-terminal domain
JOCLAFEN_01063 3.1e-14
JOCLAFEN_01064 1.1e-56 xkdJ
JOCLAFEN_01065 6.9e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
JOCLAFEN_01066 4.2e-43 yqbH S Domain of unknown function (DUF3599)
JOCLAFEN_01067 2.8e-45 yqbG S Protein of unknown function (DUF3199)
JOCLAFEN_01068 1e-157 xkdG S Phage capsid family
JOCLAFEN_01069 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
JOCLAFEN_01070 4.6e-242 yqbA S portal protein
JOCLAFEN_01071 1.5e-207 xtmB S phage terminase, large subunit
JOCLAFEN_01072 1.2e-109 xtmA L phage terminase small subunit
JOCLAFEN_01073 8.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
JOCLAFEN_01074 2e-10 yqaO S Phage-like element PBSX protein XtrA
JOCLAFEN_01077 2.5e-152 xkdC L Bacterial dnaA protein
JOCLAFEN_01079 3.1e-56 xre K Helix-turn-helix XRE-family like proteins
JOCLAFEN_01080 1.3e-110 xkdA E IrrE N-terminal-like domain
JOCLAFEN_01081 3e-110 yjqB S phage-related replication protein
JOCLAFEN_01082 4.7e-61 yjqA S Bacterial PH domain
JOCLAFEN_01083 5e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JOCLAFEN_01085 4.9e-215 S response regulator aspartate phosphatase
JOCLAFEN_01086 2.4e-78 yjoA S DinB family
JOCLAFEN_01087 1.5e-130 MA20_18170 S membrane transporter protein
JOCLAFEN_01088 1.7e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
JOCLAFEN_01089 2.9e-276 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
JOCLAFEN_01090 3.4e-183 exuR K transcriptional
JOCLAFEN_01091 6.6e-254 yjmB G symporter YjmB
JOCLAFEN_01092 5.6e-277 uxaC 5.3.1.12 G glucuronate isomerase
JOCLAFEN_01093 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
JOCLAFEN_01094 1.2e-65 yjlC S Protein of unknown function (DUF1641)
JOCLAFEN_01095 1.8e-92 yjlB S Cupin domain
JOCLAFEN_01096 1.1e-178 yjlA EG Putative multidrug resistance efflux transporter
JOCLAFEN_01097 1.9e-130 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
JOCLAFEN_01098 2.1e-121 ybbM S transport system, permease component
JOCLAFEN_01099 2.8e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JOCLAFEN_01100 6.8e-29
JOCLAFEN_01101 3e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JOCLAFEN_01102 3.6e-227 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
JOCLAFEN_01103 4.3e-92 yjgD S Protein of unknown function (DUF1641)
JOCLAFEN_01104 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
JOCLAFEN_01105 1.4e-101 yjgB S Domain of unknown function (DUF4309)
JOCLAFEN_01106 8.5e-69 T PhoQ Sensor
JOCLAFEN_01107 8.3e-21 yjfB S Putative motility protein
JOCLAFEN_01109 8.1e-106 yhiD S MgtC SapB transporter
JOCLAFEN_01112 7e-124 5.4.2.6 S Haloacid dehalogenase-like hydrolase
JOCLAFEN_01113 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
JOCLAFEN_01114 1.5e-282 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
JOCLAFEN_01115 2.6e-49 lacF 2.7.1.207 G phosphotransferase system
JOCLAFEN_01116 4.7e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOCLAFEN_01117 3.8e-218 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JOCLAFEN_01118 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JOCLAFEN_01119 3.1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JOCLAFEN_01120 1e-220 ganA 3.2.1.89 G arabinogalactan
JOCLAFEN_01121 1.4e-81 napB K helix_turn_helix multiple antibiotic resistance protein
JOCLAFEN_01122 9.1e-251 yfjF EGP Belongs to the major facilitator superfamily
JOCLAFEN_01123 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
JOCLAFEN_01124 8.5e-165 bla 3.5.2.6 V beta-lactamase
JOCLAFEN_01125 6.2e-11 yqaS L DNA packaging
JOCLAFEN_01127 3.2e-38 S YjcQ protein
JOCLAFEN_01131 5.1e-11 K Transcriptional regulator
JOCLAFEN_01133 1.5e-253 yobL S Bacterial EndoU nuclease
JOCLAFEN_01134 2.6e-22
JOCLAFEN_01135 2e-78
JOCLAFEN_01136 8.7e-31
JOCLAFEN_01144 2.1e-16 K Cro/C1-type HTH DNA-binding domain
JOCLAFEN_01148 3.9e-11
JOCLAFEN_01149 1e-171 S Pfam Transposase IS66
JOCLAFEN_01150 5e-73 L Belongs to the 'phage' integrase family
JOCLAFEN_01152 1.3e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOCLAFEN_01153 4.6e-213 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOCLAFEN_01154 7.2e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
JOCLAFEN_01155 1.2e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
JOCLAFEN_01156 5e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOCLAFEN_01157 2.7e-35 K SpoVT / AbrB like domain
JOCLAFEN_01158 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
JOCLAFEN_01159 6.8e-125 S ABC-2 type transporter
JOCLAFEN_01160 2.7e-140 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
JOCLAFEN_01161 4.6e-36
JOCLAFEN_01162 0.0 yjcD 3.6.4.12 L DNA helicase
JOCLAFEN_01163 3.8e-38 spoVIF S Stage VI sporulation protein F
JOCLAFEN_01167 4.8e-55 yjcA S Protein of unknown function (DUF1360)
JOCLAFEN_01168 1.4e-52 cotV S Spore Coat Protein X and V domain
JOCLAFEN_01169 6.8e-21 cotW
JOCLAFEN_01170 4.3e-70 cotX S Spore Coat Protein X and V domain
JOCLAFEN_01171 8.1e-90 cotY S Spore coat protein Z
JOCLAFEN_01172 2.6e-79 cotZ S Spore coat protein
JOCLAFEN_01173 7.3e-85 yjbX S Spore coat protein
JOCLAFEN_01174 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JOCLAFEN_01175 1.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOCLAFEN_01176 1.9e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
JOCLAFEN_01177 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
JOCLAFEN_01178 2.6e-29 thiS H Thiamine biosynthesis
JOCLAFEN_01179 1.4e-214 thiO 1.4.3.19 E Glycine oxidase
JOCLAFEN_01180 2.7e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
JOCLAFEN_01181 2e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JOCLAFEN_01182 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JOCLAFEN_01183 2.1e-145 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
JOCLAFEN_01184 6.3e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOCLAFEN_01185 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOCLAFEN_01186 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
JOCLAFEN_01187 6e-61 yjbL S Belongs to the UPF0738 family
JOCLAFEN_01188 4.6e-100 yjbK S protein conserved in bacteria
JOCLAFEN_01189 1.9e-116 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JOCLAFEN_01190 4.8e-72 yjbI S Bacterial-like globin
JOCLAFEN_01191 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
JOCLAFEN_01192 5.8e-19
JOCLAFEN_01193 0.0 pepF E oligoendopeptidase F
JOCLAFEN_01194 3.6e-221 yjbF S Competence protein
JOCLAFEN_01195 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JOCLAFEN_01196 3.6e-109 yjbE P Integral membrane protein TerC family
JOCLAFEN_01197 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JOCLAFEN_01198 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOCLAFEN_01199 8e-232 S Putative glycosyl hydrolase domain
JOCLAFEN_01200 6.1e-171 oppF E Belongs to the ABC transporter superfamily
JOCLAFEN_01201 2.7e-202 oppD P Belongs to the ABC transporter superfamily
JOCLAFEN_01202 1.3e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOCLAFEN_01203 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOCLAFEN_01204 0.0 oppA E ABC transporter substrate-binding protein
JOCLAFEN_01205 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
JOCLAFEN_01206 1.2e-145 yjbA S Belongs to the UPF0736 family
JOCLAFEN_01207 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOCLAFEN_01208 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOCLAFEN_01209 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
JOCLAFEN_01210 1e-187 appF E Belongs to the ABC transporter superfamily
JOCLAFEN_01211 9.7e-183 appD P Belongs to the ABC transporter superfamily
JOCLAFEN_01212 3.6e-148 yjaZ O Zn-dependent protease
JOCLAFEN_01213 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JOCLAFEN_01214 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOCLAFEN_01215 5.9e-32 yjzB
JOCLAFEN_01216 1.1e-26 comZ S ComZ
JOCLAFEN_01217 1.9e-166 med S Transcriptional activator protein med
JOCLAFEN_01218 3.6e-105 yjaV
JOCLAFEN_01219 9.9e-140 yjaU I carboxylic ester hydrolase activity
JOCLAFEN_01220 1.5e-23 yjzD S Protein of unknown function (DUF2929)
JOCLAFEN_01221 1.2e-27 yjzC S YjzC-like protein
JOCLAFEN_01222 2.1e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOCLAFEN_01223 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
JOCLAFEN_01224 1.2e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
JOCLAFEN_01225 3.1e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
JOCLAFEN_01226 1.5e-138 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
JOCLAFEN_01227 3.6e-227 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JOCLAFEN_01228 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JOCLAFEN_01229 2e-89 norB G Major Facilitator Superfamily
JOCLAFEN_01230 1.6e-271 yitY C D-arabinono-1,4-lactone oxidase
JOCLAFEN_01231 4.1e-80 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
JOCLAFEN_01232 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
JOCLAFEN_01233 1.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
JOCLAFEN_01234 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JOCLAFEN_01235 3.5e-07
JOCLAFEN_01236 4.4e-26 S Protein of unknown function (DUF3813)
JOCLAFEN_01237 2.9e-81 ipi S Intracellular proteinase inhibitor
JOCLAFEN_01238 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
JOCLAFEN_01239 7.1e-158 yitS S protein conserved in bacteria
JOCLAFEN_01241 5.8e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
JOCLAFEN_01242 1.1e-231 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
JOCLAFEN_01243 1.8e-173 yufN S ABC transporter substrate-binding protein PnrA-like
JOCLAFEN_01244 9e-161 cvfB S protein conserved in bacteria
JOCLAFEN_01245 6.6e-55 yajQ S Belongs to the UPF0234 family
JOCLAFEN_01246 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
JOCLAFEN_01247 1.1e-80 yjcF S Acetyltransferase (GNAT) domain
JOCLAFEN_01248 3.7e-71 mcbG S Pentapeptide repeats (9 copies)
JOCLAFEN_01249 1.5e-192 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOCLAFEN_01250 3.5e-74 argO S Lysine exporter protein LysE YggA
JOCLAFEN_01251 3.7e-90 yisT S DinB family
JOCLAFEN_01252 5e-159 yisR K Transcriptional regulator
JOCLAFEN_01253 9.7e-245 yisQ V Mate efflux family protein
JOCLAFEN_01254 2.4e-133 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
JOCLAFEN_01255 0.0 asnO 6.3.5.4 E Asparagine synthase
JOCLAFEN_01256 3.8e-96 yisN S Protein of unknown function (DUF2777)
JOCLAFEN_01257 1.1e-59 yisL S UPF0344 protein
JOCLAFEN_01258 1.2e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
JOCLAFEN_01259 5e-07 yisI S Spo0E like sporulation regulatory protein
JOCLAFEN_01260 8.4e-34 gerPA S Spore germination protein
JOCLAFEN_01261 6.2e-35 gerPB S cell differentiation
JOCLAFEN_01262 1.4e-62 gerPC S Spore germination protein
JOCLAFEN_01263 3.1e-23 gerPD S Spore germination protein
JOCLAFEN_01264 8.1e-64 gerPE S Spore germination protein GerPE
JOCLAFEN_01265 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
JOCLAFEN_01266 5e-50 yisB V COG1403 Restriction endonuclease
JOCLAFEN_01267 0.0 sbcC L COG0419 ATPase involved in DNA repair
JOCLAFEN_01268 3e-223 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JOCLAFEN_01269 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JOCLAFEN_01270 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
JOCLAFEN_01271 1.8e-122 ydfS S Protein of unknown function (DUF421)
JOCLAFEN_01272 9.7e-94 yhjR S Rubrerythrin
JOCLAFEN_01273 1.7e-108 K QacR-like protein, C-terminal region
JOCLAFEN_01274 2.5e-209 blt EGP Major facilitator Superfamily
JOCLAFEN_01275 2.8e-181 abrB S membrane
JOCLAFEN_01276 5.8e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
JOCLAFEN_01277 4.7e-274 yhjG CH FAD binding domain
JOCLAFEN_01278 9.2e-92 sipV 3.4.21.89 U Belongs to the peptidase S26 family
JOCLAFEN_01279 4.1e-110 yhjE S SNARE associated Golgi protein
JOCLAFEN_01280 1.7e-60 yhjD
JOCLAFEN_01281 1.4e-27 yhjC S Protein of unknown function (DUF3311)
JOCLAFEN_01282 1.6e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOCLAFEN_01283 3.3e-47 S Belongs to the UPF0145 family
JOCLAFEN_01284 8.5e-41 yhjA S Excalibur calcium-binding domain
JOCLAFEN_01285 9.6e-124 yrpD S Domain of unknown function, YrpD
JOCLAFEN_01286 5.5e-49 mepB S MepB protein
JOCLAFEN_01287 2.8e-66 frataxin S Domain of unknown function (DU1801)
JOCLAFEN_01288 3.9e-68 frataxin S Domain of unknown function (DU1801)
JOCLAFEN_01289 1.9e-109 comK K Competence transcription factor
JOCLAFEN_01290 1.8e-31 yhzC S IDEAL
JOCLAFEN_01291 3.8e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_01292 3.1e-297 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
JOCLAFEN_01293 9.1e-197 hemAT NT chemotaxis protein
JOCLAFEN_01294 9.3e-90 bioY S BioY family
JOCLAFEN_01295 3.4e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JOCLAFEN_01296 2.7e-202 vraB 2.3.1.9 I Belongs to the thiolase family
JOCLAFEN_01297 2.2e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
JOCLAFEN_01298 7.1e-153 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
JOCLAFEN_01299 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
JOCLAFEN_01300 4.8e-235 yhfN 3.4.24.84 O Peptidase M48
JOCLAFEN_01301 8.7e-66 yhfM
JOCLAFEN_01302 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
JOCLAFEN_01303 1.3e-111 yhfK GM NmrA-like family
JOCLAFEN_01304 1.3e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
JOCLAFEN_01305 9.9e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
JOCLAFEN_01306 7.9e-11 yhfH S YhfH-like protein
JOCLAFEN_01307 3.4e-228 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOCLAFEN_01308 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
JOCLAFEN_01310 7.4e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOCLAFEN_01311 3.2e-277 yhgE S YhgE Pip N-terminal domain protein
JOCLAFEN_01312 3.2e-101 yhgD K Transcriptional regulator
JOCLAFEN_01313 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JOCLAFEN_01314 8.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
JOCLAFEN_01315 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JOCLAFEN_01316 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JOCLAFEN_01317 1.3e-87 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JOCLAFEN_01318 1.4e-243 yhfA C membrane
JOCLAFEN_01319 3.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
JOCLAFEN_01320 2.5e-124 ecsC S EcsC protein family
JOCLAFEN_01321 1.9e-220 ecsB U ABC transporter
JOCLAFEN_01322 1.1e-135 ecsA V transporter (ATP-binding protein)
JOCLAFEN_01323 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
JOCLAFEN_01324 4.6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JOCLAFEN_01325 3.8e-77 trpP S Tryptophan transporter TrpP
JOCLAFEN_01326 2e-17
JOCLAFEN_01327 2.4e-38 yhaH S YtxH-like protein
JOCLAFEN_01328 8.6e-113 hpr K Negative regulator of protease production and sporulation
JOCLAFEN_01329 9.9e-55 yhaI S Protein of unknown function (DUF1878)
JOCLAFEN_01330 7e-95 yhaK S Putative zincin peptidase
JOCLAFEN_01331 1.7e-114 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JOCLAFEN_01332 3.1e-31 yhaL S Sporulation protein YhaL
JOCLAFEN_01333 1.7e-176 yhaM L Shows a 3'-5' exoribonuclease activity
JOCLAFEN_01334 0.0 yhaN L AAA domain
JOCLAFEN_01335 3.2e-236 yhaO L DNA repair exonuclease
JOCLAFEN_01336 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
JOCLAFEN_01337 6.8e-167 yhaQ S ABC transporter, ATP-binding protein
JOCLAFEN_01338 7.3e-15 S YhzD-like protein
JOCLAFEN_01339 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
JOCLAFEN_01341 3e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
JOCLAFEN_01342 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
JOCLAFEN_01343 4.6e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
JOCLAFEN_01344 9.3e-294 hemZ H coproporphyrinogen III oxidase
JOCLAFEN_01345 1.9e-158 yhaX S haloacid dehalogenase-like hydrolase
JOCLAFEN_01346 1.8e-204 yhaZ L DNA alkylation repair enzyme
JOCLAFEN_01347 1.5e-53 yheA S Belongs to the UPF0342 family
JOCLAFEN_01348 5.5e-206 yheB S Belongs to the UPF0754 family
JOCLAFEN_01349 4.8e-215 yheC HJ YheC/D like ATP-grasp
JOCLAFEN_01350 1.6e-260 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
JOCLAFEN_01351 1.7e-36 yheE S Family of unknown function (DUF5342)
JOCLAFEN_01352 2.9e-28 sspB S spore protein
JOCLAFEN_01354 4e-110 yheG GM NAD(P)H-binding
JOCLAFEN_01355 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOCLAFEN_01356 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOCLAFEN_01358 2.1e-85 T universal stress protein
JOCLAFEN_01359 8e-94 ymcC S Membrane
JOCLAFEN_01360 4.6e-88 pksA K Transcriptional regulator
JOCLAFEN_01361 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
JOCLAFEN_01362 1e-156 yheN G deacetylase
JOCLAFEN_01363 6.5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
JOCLAFEN_01364 4.6e-205 yhdY M Mechanosensitive ion channel
JOCLAFEN_01366 1.7e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOCLAFEN_01367 3.9e-58 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOCLAFEN_01368 9.4e-51 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOCLAFEN_01369 2.4e-256 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
JOCLAFEN_01370 1.9e-236 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JOCLAFEN_01371 1.1e-225 yhdR 2.6.1.1 E Aminotransferase
JOCLAFEN_01372 4.3e-71 cueR K transcriptional
JOCLAFEN_01373 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JOCLAFEN_01374 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JOCLAFEN_01375 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
JOCLAFEN_01376 1.2e-199 yhdL S Sigma factor regulator N-terminal
JOCLAFEN_01377 8.1e-45 yhdK S Sigma-M inhibitor protein
JOCLAFEN_01378 5.7e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JOCLAFEN_01379 2e-250 yhdG E amino acid
JOCLAFEN_01380 1.2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_01381 4.9e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
JOCLAFEN_01382 9e-164 citR K Transcriptional regulator
JOCLAFEN_01383 1.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOCLAFEN_01384 6.4e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
JOCLAFEN_01385 1.2e-271 ycgB S Stage V sporulation protein R
JOCLAFEN_01386 2e-256 ygxB M Conserved TM helix
JOCLAFEN_01387 1.9e-74 nsrR K Transcriptional regulator
JOCLAFEN_01388 2e-216 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOCLAFEN_01389 3.1e-53 yhdC S Protein of unknown function (DUF3889)
JOCLAFEN_01390 2.5e-39 yhdB S YhdB-like protein
JOCLAFEN_01391 1.9e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
JOCLAFEN_01392 7.7e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOCLAFEN_01393 5e-207 yhcY 2.7.13.3 T Histidine kinase
JOCLAFEN_01394 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
JOCLAFEN_01395 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JOCLAFEN_01396 7e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JOCLAFEN_01397 4.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
JOCLAFEN_01398 1.5e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
JOCLAFEN_01399 1.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOCLAFEN_01408 9e-78 tspO T membrane
JOCLAFEN_01409 5.7e-132 dksA T COG1734 DnaK suppressor protein
JOCLAFEN_01410 5.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
JOCLAFEN_01411 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JOCLAFEN_01412 2.1e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
JOCLAFEN_01413 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JOCLAFEN_01414 5.9e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JOCLAFEN_01415 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
JOCLAFEN_01416 2.3e-24 S Domain of Unknown Function (DUF1540)
JOCLAFEN_01417 1.7e-185 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
JOCLAFEN_01418 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
JOCLAFEN_01419 1.6e-41 rpmE2 J Ribosomal protein L31
JOCLAFEN_01420 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
JOCLAFEN_01421 8.9e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JOCLAFEN_01422 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JOCLAFEN_01423 3.6e-76 ytkA S YtkA-like
JOCLAFEN_01425 1.6e-76 dps P Belongs to the Dps family
JOCLAFEN_01426 1.7e-61 ytkC S Bacteriophage holin family
JOCLAFEN_01427 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
JOCLAFEN_01428 2.4e-126 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
JOCLAFEN_01429 3.2e-144 ytlC P ABC transporter
JOCLAFEN_01430 3.3e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
JOCLAFEN_01431 3.9e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
JOCLAFEN_01432 1.6e-38 ytmB S Protein of unknown function (DUF2584)
JOCLAFEN_01433 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JOCLAFEN_01434 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JOCLAFEN_01435 0.0 asnB 6.3.5.4 E Asparagine synthase
JOCLAFEN_01436 3.7e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
JOCLAFEN_01437 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JOCLAFEN_01438 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
JOCLAFEN_01439 2.9e-212 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
JOCLAFEN_01440 8.6e-145 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
JOCLAFEN_01442 8.7e-107 ytqB J Putative rRNA methylase
JOCLAFEN_01443 2.1e-190 yhcC S Fe-S oxidoreductase
JOCLAFEN_01444 3.5e-286 norB EGP COG0477 Permeases of the major facilitator superfamily
JOCLAFEN_01445 2e-189 K helix_turn_helix, Arsenical Resistance Operon Repressor
JOCLAFEN_01446 7.4e-40 ytzC S Protein of unknown function (DUF2524)
JOCLAFEN_01448 3.9e-66 ytrA K GntR family transcriptional regulator
JOCLAFEN_01449 3.8e-162 ytrB P abc transporter atp-binding protein
JOCLAFEN_01450 6.5e-171 S ABC-2 family transporter protein
JOCLAFEN_01451 6.3e-166 P ABC-2 family transporter protein
JOCLAFEN_01452 2.6e-159
JOCLAFEN_01453 1.3e-125 ytrE V ABC transporter, ATP-binding protein
JOCLAFEN_01454 1.1e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
JOCLAFEN_01455 8.2e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_01456 3.2e-170 T PhoQ Sensor
JOCLAFEN_01457 5.8e-135 bceA V ABC transporter, ATP-binding protein
JOCLAFEN_01458 0.0 bceB V ABC transporter (permease)
JOCLAFEN_01459 3.6e-126 ywaF S Integral membrane protein
JOCLAFEN_01460 7.3e-209 yttB EGP Major facilitator Superfamily
JOCLAFEN_01461 6.6e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
JOCLAFEN_01462 1.2e-52 ytvB S Protein of unknown function (DUF4257)
JOCLAFEN_01463 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOCLAFEN_01464 2.1e-51 ytwF P Sulfurtransferase
JOCLAFEN_01465 6.2e-52 M Acetyltransferase (GNAT) domain
JOCLAFEN_01466 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
JOCLAFEN_01467 1.4e-142 amyC P ABC transporter (permease)
JOCLAFEN_01468 7.4e-169 amyD G Binding-protein-dependent transport system inner membrane component
JOCLAFEN_01469 1.8e-245 msmE G Bacterial extracellular solute-binding protein
JOCLAFEN_01470 7.5e-186 msmR K Transcriptional regulator
JOCLAFEN_01471 9e-26 yteV S Sporulation protein Cse60
JOCLAFEN_01472 5.8e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
JOCLAFEN_01473 3.3e-236 ytfP S HI0933-like protein
JOCLAFEN_01474 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOCLAFEN_01475 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JOCLAFEN_01476 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
JOCLAFEN_01477 4.1e-127 ythP V ABC transporter
JOCLAFEN_01478 1.9e-217 ythQ U Bacterial ABC transporter protein EcsB
JOCLAFEN_01479 5.3e-229 pbuO S permease
JOCLAFEN_01480 5.1e-270 pepV 3.5.1.18 E Dipeptidase
JOCLAFEN_01481 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JOCLAFEN_01482 6.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JOCLAFEN_01483 2.3e-165 ytlQ
JOCLAFEN_01484 1.4e-178 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
JOCLAFEN_01485 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
JOCLAFEN_01486 3.5e-45 ytzH S YtzH-like protein
JOCLAFEN_01487 5.2e-124 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JOCLAFEN_01488 4.6e-165 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
JOCLAFEN_01489 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
JOCLAFEN_01490 1.7e-51 ytzB S small secreted protein
JOCLAFEN_01491 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
JOCLAFEN_01492 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
JOCLAFEN_01493 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JOCLAFEN_01494 3.7e-148 ytpQ S Belongs to the UPF0354 family
JOCLAFEN_01495 7e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOCLAFEN_01496 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
JOCLAFEN_01497 9.3e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JOCLAFEN_01498 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JOCLAFEN_01499 1.7e-16 ytxH S COG4980 Gas vesicle protein
JOCLAFEN_01500 1.7e-43 ytxJ O Protein of unknown function (DUF2847)
JOCLAFEN_01501 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
JOCLAFEN_01502 2.9e-182 ccpA K catabolite control protein A
JOCLAFEN_01503 5.1e-145 motA N flagellar motor
JOCLAFEN_01504 4.1e-119 motS N Flagellar motor protein
JOCLAFEN_01505 1.1e-230 acuC BQ histone deacetylase
JOCLAFEN_01506 9.3e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
JOCLAFEN_01507 8e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
JOCLAFEN_01508 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JOCLAFEN_01509 6.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOCLAFEN_01510 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
JOCLAFEN_01511 5.2e-125 azlC E AzlC protein
JOCLAFEN_01512 4.4e-149 K Transcriptional regulator
JOCLAFEN_01513 1.1e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOCLAFEN_01514 5.9e-140 E GDSL-like Lipase/Acylhydrolase family
JOCLAFEN_01516 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
JOCLAFEN_01517 7.3e-09
JOCLAFEN_01518 3e-215 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JOCLAFEN_01519 1e-58 UW Hep Hag repeat protein
JOCLAFEN_01522 2e-100 yokH G SMI1 / KNR4 family
JOCLAFEN_01523 5.4e-256 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JOCLAFEN_01524 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JOCLAFEN_01525 5e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
JOCLAFEN_01526 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
JOCLAFEN_01527 7.7e-109 yttP K Transcriptional regulator
JOCLAFEN_01528 4.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
JOCLAFEN_01529 1.2e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JOCLAFEN_01530 6.9e-240 braB E Component of the transport system for branched-chain amino acids
JOCLAFEN_01531 4.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
JOCLAFEN_01532 3.9e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOCLAFEN_01533 3.9e-31 sspB S spore protein
JOCLAFEN_01534 8.5e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
JOCLAFEN_01535 0.0 ytcJ S amidohydrolase
JOCLAFEN_01536 5.7e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOCLAFEN_01537 7.1e-181 sppA OU signal peptide peptidase SppA
JOCLAFEN_01538 4.5e-88 yteJ S RDD family
JOCLAFEN_01539 3.8e-109 ytfI S Protein of unknown function (DUF2953)
JOCLAFEN_01540 1.6e-60 ytfJ S Sporulation protein YtfJ
JOCLAFEN_01541 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JOCLAFEN_01542 5.1e-184 ytxK 2.1.1.72 L DNA methylase
JOCLAFEN_01543 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOCLAFEN_01544 2.1e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
JOCLAFEN_01545 2.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
JOCLAFEN_01546 5.4e-264 argH 4.3.2.1 E argininosuccinate lyase
JOCLAFEN_01548 4.5e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_01549 1.1e-129 ytkL S Belongs to the UPF0173 family
JOCLAFEN_01550 7.5e-239 ytoI K transcriptional regulator containing CBS domains
JOCLAFEN_01551 1.5e-46 ytpI S YtpI-like protein
JOCLAFEN_01552 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
JOCLAFEN_01553 4.4e-23
JOCLAFEN_01554 5.1e-87 ytrI
JOCLAFEN_01555 3.2e-56 ytrH S Sporulation protein YtrH
JOCLAFEN_01556 0.0 dnaE 2.7.7.7 L DNA polymerase
JOCLAFEN_01557 3.7e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
JOCLAFEN_01558 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JOCLAFEN_01559 1.2e-180 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
JOCLAFEN_01560 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
JOCLAFEN_01561 1.3e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JOCLAFEN_01562 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
JOCLAFEN_01563 1.1e-193 ytvI S sporulation integral membrane protein YtvI
JOCLAFEN_01564 1.5e-72 yeaL S membrane
JOCLAFEN_01565 8.5e-48 yjdF S Protein of unknown function (DUF2992)
JOCLAFEN_01566 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
JOCLAFEN_01567 3.1e-242 icd 1.1.1.42 C isocitrate
JOCLAFEN_01568 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
JOCLAFEN_01569 3.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_01570 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
JOCLAFEN_01571 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOCLAFEN_01572 8e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JOCLAFEN_01573 2.1e-106 ytaF P Probably functions as a manganese efflux pump
JOCLAFEN_01574 5.2e-99 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JOCLAFEN_01575 1.5e-160 ytbE S reductase
JOCLAFEN_01576 6.4e-205 ytbD EGP Major facilitator Superfamily
JOCLAFEN_01577 2e-67 ytcD K Transcriptional regulator
JOCLAFEN_01578 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JOCLAFEN_01579 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JOCLAFEN_01580 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JOCLAFEN_01581 4.5e-258 dnaB L Membrane attachment protein
JOCLAFEN_01582 1e-156 dnaI L Primosomal protein DnaI
JOCLAFEN_01583 2.7e-109 ytxB S SNARE associated Golgi protein
JOCLAFEN_01584 6.7e-153 ytxC S YtxC-like family
JOCLAFEN_01585 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOCLAFEN_01586 1.3e-150 ysaA S HAD-hyrolase-like
JOCLAFEN_01587 0.0 lytS 2.7.13.3 T Histidine kinase
JOCLAFEN_01588 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
JOCLAFEN_01589 3.1e-40 lrgA S effector of murein hydrolase LrgA
JOCLAFEN_01590 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
JOCLAFEN_01591 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JOCLAFEN_01592 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JOCLAFEN_01593 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JOCLAFEN_01594 7.7e-42 ysdA S Membrane
JOCLAFEN_01595 9.2e-68 ysdB S Sigma-w pathway protein YsdB
JOCLAFEN_01596 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
JOCLAFEN_01597 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JOCLAFEN_01598 2.8e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JOCLAFEN_01599 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
JOCLAFEN_01600 9.3e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
JOCLAFEN_01601 1.3e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
JOCLAFEN_01602 9.4e-225 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
JOCLAFEN_01603 7.6e-252 araN G carbohydrate transport
JOCLAFEN_01604 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
JOCLAFEN_01605 1.2e-144 araQ G transport system permease
JOCLAFEN_01606 8.6e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
JOCLAFEN_01607 0.0 cstA T Carbon starvation protein
JOCLAFEN_01608 9.8e-255 glcF C Glycolate oxidase
JOCLAFEN_01609 2.4e-259 glcD 1.1.3.15 C FAD binding domain
JOCLAFEN_01610 7.6e-205 ysfB KT regulator
JOCLAFEN_01611 2e-32 sspI S Belongs to the SspI family
JOCLAFEN_01612 2.4e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOCLAFEN_01613 5.2e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JOCLAFEN_01614 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOCLAFEN_01615 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOCLAFEN_01616 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JOCLAFEN_01617 1.6e-83 cvpA S membrane protein, required for colicin V production
JOCLAFEN_01618 0.0 polX L COG1796 DNA polymerase IV (family X)
JOCLAFEN_01619 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JOCLAFEN_01620 4.7e-67 yshE S membrane
JOCLAFEN_01621 6.6e-122 ywbB S Protein of unknown function (DUF2711)
JOCLAFEN_01622 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JOCLAFEN_01623 9.2e-104 fadR K Transcriptional regulator
JOCLAFEN_01624 1.9e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JOCLAFEN_01625 5.7e-138 etfB C Electron transfer flavoprotein
JOCLAFEN_01626 1.4e-178 etfA C Electron transfer flavoprotein
JOCLAFEN_01627 1.1e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JOCLAFEN_01628 2.5e-52 trxA O Belongs to the thioredoxin family
JOCLAFEN_01629 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JOCLAFEN_01630 7.8e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JOCLAFEN_01631 7.7e-79 yslB S Protein of unknown function (DUF2507)
JOCLAFEN_01632 4.8e-108 sdhC C succinate dehydrogenase
JOCLAFEN_01633 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JOCLAFEN_01634 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
JOCLAFEN_01635 3.2e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
JOCLAFEN_01636 2e-30 gerE K Transcriptional regulator
JOCLAFEN_01637 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
JOCLAFEN_01638 7.8e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JOCLAFEN_01639 1.4e-198 gerM S COG5401 Spore germination protein
JOCLAFEN_01640 5.8e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JOCLAFEN_01641 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JOCLAFEN_01642 7e-92 ysnB S Phosphoesterase
JOCLAFEN_01646 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
JOCLAFEN_01647 6.2e-247 hsdM 2.1.1.72 L type I restriction-modification system
JOCLAFEN_01648 2e-96 hsdS 3.1.21.3 V restriction modification system DNA specificity
JOCLAFEN_01649 8.3e-13 pinR3 L Resolvase, N terminal domain
JOCLAFEN_01652 0.0 ilvB 2.2.1.6 E Acetolactate synthase
JOCLAFEN_01653 5.4e-84 ilvN 2.2.1.6 E Acetolactate synthase
JOCLAFEN_01654 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JOCLAFEN_01655 1.8e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JOCLAFEN_01656 5.3e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
JOCLAFEN_01657 5.3e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOCLAFEN_01658 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JOCLAFEN_01659 2.1e-188 ysoA H Tetratricopeptide repeat
JOCLAFEN_01660 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JOCLAFEN_01661 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JOCLAFEN_01662 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
JOCLAFEN_01663 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JOCLAFEN_01664 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
JOCLAFEN_01665 1.5e-88 ysxD
JOCLAFEN_01666 1.3e-246 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JOCLAFEN_01667 3.6e-146 hemX O cytochrome C
JOCLAFEN_01668 2.1e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
JOCLAFEN_01669 6.6e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
JOCLAFEN_01670 1e-184 hemB 4.2.1.24 H Belongs to the ALAD family
JOCLAFEN_01671 3.6e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JOCLAFEN_01672 1e-220 spoVID M stage VI sporulation protein D
JOCLAFEN_01673 7.3e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JOCLAFEN_01674 2.1e-25
JOCLAFEN_01675 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JOCLAFEN_01676 1.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JOCLAFEN_01677 3.5e-132 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
JOCLAFEN_01678 8.7e-139 spoIIB S Sporulation related domain
JOCLAFEN_01679 1.2e-100 maf D septum formation protein Maf
JOCLAFEN_01680 1.8e-127 radC E Belongs to the UPF0758 family
JOCLAFEN_01681 4e-184 mreB D Rod shape-determining protein MreB
JOCLAFEN_01682 1.2e-157 mreC M Involved in formation and maintenance of cell shape
JOCLAFEN_01683 1.4e-84 mreD M shape-determining protein
JOCLAFEN_01684 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
JOCLAFEN_01685 8e-143 minD D Belongs to the ParA family
JOCLAFEN_01686 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
JOCLAFEN_01687 1.6e-160 spoIVFB S Stage IV sporulation protein
JOCLAFEN_01688 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
JOCLAFEN_01689 3.2e-56 ysxB J ribosomal protein
JOCLAFEN_01690 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JOCLAFEN_01691 8.7e-107 spo0B T Sporulation initiation phospho-transferase B, C-terminal
JOCLAFEN_01692 7.6e-236 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JOCLAFEN_01693 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
JOCLAFEN_01694 2.6e-160 pheA 4.2.1.51 E Prephenate dehydratase
JOCLAFEN_01695 1.1e-95 niaR S small molecule binding protein (contains 3H domain)
JOCLAFEN_01696 2.7e-224 nifS 2.8.1.7 E Cysteine desulfurase
JOCLAFEN_01697 3.4e-299 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
JOCLAFEN_01698 5.3e-153 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
JOCLAFEN_01699 1.8e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JOCLAFEN_01700 1e-146 safA M spore coat assembly protein SafA
JOCLAFEN_01701 3e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOCLAFEN_01703 1.4e-92 bofC S BofC C-terminal domain
JOCLAFEN_01704 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JOCLAFEN_01705 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JOCLAFEN_01706 1.6e-20 yrzS S Protein of unknown function (DUF2905)
JOCLAFEN_01707 1.6e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JOCLAFEN_01708 1.4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JOCLAFEN_01709 2.1e-36 yajC U Preprotein translocase subunit YajC
JOCLAFEN_01710 2.4e-60 yrzE S Protein of unknown function (DUF3792)
JOCLAFEN_01711 9.5e-110 yrbG S membrane
JOCLAFEN_01712 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOCLAFEN_01713 1.3e-50 yrzD S Post-transcriptional regulator
JOCLAFEN_01714 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JOCLAFEN_01715 4.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
JOCLAFEN_01716 5.2e-48 yrvD S Lipopolysaccharide assembly protein A domain
JOCLAFEN_01717 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JOCLAFEN_01718 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JOCLAFEN_01719 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOCLAFEN_01720 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JOCLAFEN_01721 1.5e-278 lytH 3.5.1.28 M COG3103 SH3 domain protein
JOCLAFEN_01724 2.8e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
JOCLAFEN_01725 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JOCLAFEN_01726 7.4e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
JOCLAFEN_01727 5.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
JOCLAFEN_01728 7.8e-64 cymR K Transcriptional regulator
JOCLAFEN_01729 1e-212 iscS 2.8.1.7 E Cysteine desulfurase
JOCLAFEN_01730 3.5e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JOCLAFEN_01731 1.7e-18 S COG0457 FOG TPR repeat
JOCLAFEN_01732 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JOCLAFEN_01733 1.8e-83 yrrD S protein conserved in bacteria
JOCLAFEN_01734 2.9e-30 yrzR
JOCLAFEN_01735 2.1e-08 S Protein of unknown function (DUF3918)
JOCLAFEN_01736 2.2e-106 glnP P ABC transporter
JOCLAFEN_01737 4.7e-109 gluC P ABC transporter
JOCLAFEN_01738 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
JOCLAFEN_01739 1.1e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOCLAFEN_01740 5.2e-166 yrrI S AI-2E family transporter
JOCLAFEN_01741 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JOCLAFEN_01742 1.7e-41 yrzL S Belongs to the UPF0297 family
JOCLAFEN_01743 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JOCLAFEN_01744 7.1e-46 yrzB S Belongs to the UPF0473 family
JOCLAFEN_01745 4.8e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOCLAFEN_01746 2.1e-117 yrrM 2.1.1.104 S O-methyltransferase
JOCLAFEN_01747 1.7e-173 yegQ O Peptidase U32
JOCLAFEN_01748 1.6e-246 yegQ O COG0826 Collagenase and related proteases
JOCLAFEN_01749 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
JOCLAFEN_01750 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JOCLAFEN_01751 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
JOCLAFEN_01752 3.4e-68 yrrS S Protein of unknown function (DUF1510)
JOCLAFEN_01753 4.1e-27 yrzA S Protein of unknown function (DUF2536)
JOCLAFEN_01754 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
JOCLAFEN_01755 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JOCLAFEN_01756 4.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
JOCLAFEN_01757 1.3e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
JOCLAFEN_01758 1.8e-34 yrhC S YrhC-like protein
JOCLAFEN_01759 2.9e-79 yrhD S Protein of unknown function (DUF1641)
JOCLAFEN_01760 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
JOCLAFEN_01761 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
JOCLAFEN_01762 8e-143 focA P Formate nitrite
JOCLAFEN_01764 3.9e-93 yrhH Q methyltransferase
JOCLAFEN_01765 2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
JOCLAFEN_01766 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JOCLAFEN_01767 5.5e-212 ynfM EGP Major facilitator Superfamily
JOCLAFEN_01768 1.1e-164 yybE K Transcriptional regulator
JOCLAFEN_01769 1.2e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOCLAFEN_01770 5.3e-183 romA S Beta-lactamase superfamily domain
JOCLAFEN_01771 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
JOCLAFEN_01772 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
JOCLAFEN_01773 1.8e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
JOCLAFEN_01774 7.9e-91 glvR K Helix-turn-helix domain, rpiR family
JOCLAFEN_01775 1.3e-29 glvR K Helix-turn-helix domain, rpiR family
JOCLAFEN_01776 1.5e-144 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
JOCLAFEN_01777 7.7e-146 S hydrolase
JOCLAFEN_01779 1.1e-92 yrdA S DinB family
JOCLAFEN_01780 5.7e-81 yyaR K Acetyltransferase (GNAT) domain
JOCLAFEN_01781 4.8e-158 tetL EGP Major facilitator Superfamily
JOCLAFEN_01782 1.1e-50 tetL EGP Major facilitator Superfamily
JOCLAFEN_01783 4e-98 adk 2.7.4.3 F adenylate kinase activity
JOCLAFEN_01784 1.2e-147 ydeE K AraC family transcriptional regulator
JOCLAFEN_01786 2.9e-20 S SMI1-KNR4 cell-wall
JOCLAFEN_01787 8.7e-193 yobL S Bacterial EndoU nuclease
JOCLAFEN_01788 9.4e-92 K Transcriptional regulator PadR-like family
JOCLAFEN_01789 8.4e-159 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
JOCLAFEN_01790 4e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOCLAFEN_01791 2.2e-216 EGP Major facilitator Superfamily
JOCLAFEN_01792 2.2e-39 2.3.1.57 K Acetyltransferase (GNAT) domain
JOCLAFEN_01793 9.4e-107 yqeD S SNARE associated Golgi protein
JOCLAFEN_01794 5.8e-140 3.5.1.104 G Polysaccharide deacetylase
JOCLAFEN_01795 7.7e-140 yqeF E GDSL-like Lipase/Acylhydrolase
JOCLAFEN_01797 2e-94 yqeG S hydrolase of the HAD superfamily
JOCLAFEN_01798 5.9e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
JOCLAFEN_01799 1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JOCLAFEN_01800 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
JOCLAFEN_01801 2.3e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JOCLAFEN_01802 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
JOCLAFEN_01803 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JOCLAFEN_01804 2.2e-139 yqeM Q Methyltransferase
JOCLAFEN_01805 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOCLAFEN_01806 8.1e-103 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
JOCLAFEN_01807 8e-105 comEB 3.5.4.12 F ComE operon protein 2
JOCLAFEN_01808 0.0 comEC S Competence protein ComEC
JOCLAFEN_01809 2.5e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
JOCLAFEN_01810 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
JOCLAFEN_01811 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
JOCLAFEN_01812 1.4e-220 spoIIP M stage II sporulation protein P
JOCLAFEN_01813 2.5e-53 yqxA S Protein of unknown function (DUF3679)
JOCLAFEN_01814 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JOCLAFEN_01815 1.4e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
JOCLAFEN_01816 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JOCLAFEN_01817 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JOCLAFEN_01818 0.0 dnaK O Heat shock 70 kDa protein
JOCLAFEN_01819 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JOCLAFEN_01820 1.6e-174 prmA J Methylates ribosomal protein L11
JOCLAFEN_01821 5.1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JOCLAFEN_01822 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
JOCLAFEN_01823 1e-157 yqeW P COG1283 Na phosphate symporter
JOCLAFEN_01824 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JOCLAFEN_01825 1.2e-68 yqeY S Yqey-like protein
JOCLAFEN_01826 4.4e-231 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
JOCLAFEN_01827 8.1e-121 yqfA S UPF0365 protein
JOCLAFEN_01828 3.4e-55 yqfB
JOCLAFEN_01829 9.3e-46 yqfC S sporulation protein YqfC
JOCLAFEN_01830 6.8e-215 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
JOCLAFEN_01831 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
JOCLAFEN_01832 0.0 yqfF S membrane-associated HD superfamily hydrolase
JOCLAFEN_01833 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JOCLAFEN_01834 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JOCLAFEN_01835 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JOCLAFEN_01836 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JOCLAFEN_01837 1.8e-16 S YqzL-like protein
JOCLAFEN_01838 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
JOCLAFEN_01839 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JOCLAFEN_01840 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JOCLAFEN_01841 9.9e-112 ccpN K CBS domain
JOCLAFEN_01842 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JOCLAFEN_01843 6.7e-87 yaiI S Belongs to the UPF0178 family
JOCLAFEN_01844 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JOCLAFEN_01845 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JOCLAFEN_01846 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
JOCLAFEN_01847 2.2e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
JOCLAFEN_01848 2.5e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JOCLAFEN_01849 1.7e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JOCLAFEN_01850 6.2e-51 yqfQ S YqfQ-like protein
JOCLAFEN_01851 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JOCLAFEN_01852 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JOCLAFEN_01853 9.3e-37 yqfT S Protein of unknown function (DUF2624)
JOCLAFEN_01854 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JOCLAFEN_01855 2.9e-72 zur P Belongs to the Fur family
JOCLAFEN_01856 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
JOCLAFEN_01857 2.3e-52 yqfX S membrane
JOCLAFEN_01858 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JOCLAFEN_01859 3.7e-48 yqfZ M LysM domain
JOCLAFEN_01860 1.6e-129 yqgB S Protein of unknown function (DUF1189)
JOCLAFEN_01861 3e-76 yqgC S protein conserved in bacteria
JOCLAFEN_01862 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
JOCLAFEN_01863 4.5e-228 yqgE EGP Major facilitator superfamily
JOCLAFEN_01864 0.0 pbpA 3.4.16.4 M penicillin-binding protein
JOCLAFEN_01865 1.7e-157 pstS P Phosphate
JOCLAFEN_01866 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
JOCLAFEN_01867 1.8e-156 pstA P Phosphate transport system permease
JOCLAFEN_01868 9.2e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOCLAFEN_01869 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOCLAFEN_01870 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOCLAFEN_01871 1.2e-50 yqzD
JOCLAFEN_01872 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JOCLAFEN_01873 1e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JOCLAFEN_01874 4e-07 yqgO
JOCLAFEN_01875 3.3e-212 nhaC C Na H antiporter
JOCLAFEN_01876 1.4e-178 glcK 2.7.1.2 G Glucokinase
JOCLAFEN_01877 1.2e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
JOCLAFEN_01878 1.6e-199 yqgU
JOCLAFEN_01879 6.9e-50 yqgV S Thiamine-binding protein
JOCLAFEN_01880 5.4e-20 yqgW S Protein of unknown function (DUF2759)
JOCLAFEN_01881 1.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
JOCLAFEN_01882 3.1e-37 yqgY S Protein of unknown function (DUF2626)
JOCLAFEN_01883 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
JOCLAFEN_01885 3.8e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOCLAFEN_01886 3.3e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
JOCLAFEN_01887 5.9e-185 corA P Mg2 transporter protein
JOCLAFEN_01888 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JOCLAFEN_01889 2.9e-185 comGB NU COG1459 Type II secretory pathway, component PulF
JOCLAFEN_01890 8.9e-50 comGC U Required for transformation and DNA binding
JOCLAFEN_01891 1.6e-73 gspH NU Tfp pilus assembly protein FimT
JOCLAFEN_01892 7.6e-20 comGE
JOCLAFEN_01893 5.2e-66 comGF U Putative Competence protein ComGF
JOCLAFEN_01894 4.3e-62 S ComG operon protein 7
JOCLAFEN_01895 2.3e-26 yqzE S YqzE-like protein
JOCLAFEN_01896 8.3e-54 yqzG S Protein of unknown function (DUF3889)
JOCLAFEN_01897 3.8e-122 yqxM
JOCLAFEN_01898 1.3e-70 sipW 3.4.21.89 U Signal peptidase
JOCLAFEN_01899 3.3e-141 tasA S Cell division protein FtsN
JOCLAFEN_01900 7.8e-55 sinR K transcriptional
JOCLAFEN_01901 5.2e-23 sinI S Anti-repressor SinI
JOCLAFEN_01902 6e-151 yqhG S Bacterial protein YqhG of unknown function
JOCLAFEN_01903 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
JOCLAFEN_01904 1.4e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
JOCLAFEN_01905 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JOCLAFEN_01906 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JOCLAFEN_01907 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
JOCLAFEN_01908 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
JOCLAFEN_01909 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
JOCLAFEN_01910 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
JOCLAFEN_01911 3.4e-62 yqhP
JOCLAFEN_01912 1e-173 yqhQ S Protein of unknown function (DUF1385)
JOCLAFEN_01913 3.7e-88 yqhR S Conserved membrane protein YqhR
JOCLAFEN_01914 1.1e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
JOCLAFEN_01915 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JOCLAFEN_01916 1.8e-36 yqhV S Protein of unknown function (DUF2619)
JOCLAFEN_01917 4.2e-172 spoIIIAA S stage III sporulation protein AA
JOCLAFEN_01918 1.7e-85 spoIIIAB S Stage III sporulation protein
JOCLAFEN_01919 7.6e-29 spoIIIAC S stage III sporulation protein AC
JOCLAFEN_01920 2.5e-41 spoIIIAD S Stage III sporulation protein AD
JOCLAFEN_01921 1.1e-199 spoIIIAE S stage III sporulation protein AE
JOCLAFEN_01922 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
JOCLAFEN_01923 2.2e-117 spoIIIAG S stage III sporulation protein AG
JOCLAFEN_01924 2.5e-62 spoIIIAH S SpoIIIAH-like protein
JOCLAFEN_01925 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JOCLAFEN_01926 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
JOCLAFEN_01927 8.1e-67 yqhY S protein conserved in bacteria
JOCLAFEN_01928 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOCLAFEN_01929 2.2e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JOCLAFEN_01930 6e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOCLAFEN_01931 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOCLAFEN_01932 3.6e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JOCLAFEN_01933 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JOCLAFEN_01934 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
JOCLAFEN_01935 3.9e-78 argR K Regulates arginine biosynthesis genes
JOCLAFEN_01936 3.5e-305 recN L May be involved in recombinational repair of damaged DNA
JOCLAFEN_01937 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
JOCLAFEN_01938 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
JOCLAFEN_01939 1.4e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOCLAFEN_01942 3.2e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
JOCLAFEN_01944 1.8e-113 K Protein of unknown function (DUF1232)
JOCLAFEN_01945 1.5e-101 ytaF P Probably functions as a manganese efflux pump
JOCLAFEN_01946 2.5e-17
JOCLAFEN_01947 1.2e-104 amiC 3.5.1.28 M Cell wall hydrolase autolysin
JOCLAFEN_01948 3.3e-135 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOCLAFEN_01949 1.7e-213 mmgA 2.3.1.9 I Belongs to the thiolase family
JOCLAFEN_01950 4.8e-154 hbdA 1.1.1.157 I Dehydrogenase
JOCLAFEN_01951 6.1e-205 mmgC I acyl-CoA dehydrogenase
JOCLAFEN_01952 2.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
JOCLAFEN_01953 2e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
JOCLAFEN_01954 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JOCLAFEN_01955 3.2e-34 yqzF S Protein of unknown function (DUF2627)
JOCLAFEN_01956 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
JOCLAFEN_01957 3.1e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
JOCLAFEN_01958 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOCLAFEN_01959 7.5e-208 buk 2.7.2.7 C Belongs to the acetokinase family
JOCLAFEN_01960 1.8e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOCLAFEN_01961 7.5e-167 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOCLAFEN_01962 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOCLAFEN_01963 1.8e-202 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOCLAFEN_01964 1.6e-171 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JOCLAFEN_01965 1e-75 yqiW S Belongs to the UPF0403 family
JOCLAFEN_01966 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
JOCLAFEN_01967 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
JOCLAFEN_01968 7.7e-155 yloC S stress-induced protein
JOCLAFEN_01969 1.5e-40 ylzA S Belongs to the UPF0296 family
JOCLAFEN_01970 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JOCLAFEN_01971 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JOCLAFEN_01972 9.7e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOCLAFEN_01973 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOCLAFEN_01974 2.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JOCLAFEN_01975 3e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JOCLAFEN_01976 5.1e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JOCLAFEN_01977 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
JOCLAFEN_01978 1.7e-139 stp 3.1.3.16 T phosphatase
JOCLAFEN_01979 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JOCLAFEN_01980 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JOCLAFEN_01981 1.2e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JOCLAFEN_01982 4.9e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
JOCLAFEN_01983 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JOCLAFEN_01984 5.5e-59 asp S protein conserved in bacteria
JOCLAFEN_01985 1.1e-303 yloV S kinase related to dihydroxyacetone kinase
JOCLAFEN_01986 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
JOCLAFEN_01987 7.1e-156 sdaAA 4.3.1.17 E L-serine dehydratase
JOCLAFEN_01988 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JOCLAFEN_01989 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
JOCLAFEN_01990 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JOCLAFEN_01991 5.9e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOCLAFEN_01992 4.6e-129 IQ reductase
JOCLAFEN_01993 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOCLAFEN_01994 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JOCLAFEN_01995 0.0 smc D Required for chromosome condensation and partitioning
JOCLAFEN_01996 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JOCLAFEN_01997 4.5e-143 S Phosphotransferase enzyme family
JOCLAFEN_01998 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JOCLAFEN_01999 1.8e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JOCLAFEN_02000 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JOCLAFEN_02001 1.7e-35 ylqC S Belongs to the UPF0109 family
JOCLAFEN_02002 1.3e-61 ylqD S YlqD protein
JOCLAFEN_02003 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JOCLAFEN_02004 8.3e-139 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JOCLAFEN_02005 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JOCLAFEN_02006 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JOCLAFEN_02007 5.3e-128 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOCLAFEN_02008 4.9e-307 ylqG
JOCLAFEN_02009 2.3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
JOCLAFEN_02010 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
JOCLAFEN_02011 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
JOCLAFEN_02012 3.3e-169 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
JOCLAFEN_02013 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOCLAFEN_02014 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JOCLAFEN_02015 7.2e-172 xerC L tyrosine recombinase XerC
JOCLAFEN_02016 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JOCLAFEN_02017 1.6e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JOCLAFEN_02018 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
JOCLAFEN_02019 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
JOCLAFEN_02020 1.2e-74 flgC N Belongs to the flagella basal body rod proteins family
JOCLAFEN_02021 2.5e-31 fliE N Flagellar hook-basal body
JOCLAFEN_02022 1.4e-263 fliF N The M ring may be actively involved in energy transduction
JOCLAFEN_02023 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JOCLAFEN_02024 1.4e-88 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
JOCLAFEN_02025 5.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
JOCLAFEN_02026 4.5e-71 fliJ N Flagellar biosynthesis chaperone
JOCLAFEN_02027 4.4e-48 ylxF S MgtE intracellular N domain
JOCLAFEN_02028 1e-203 fliK N Flagellar hook-length control protein
JOCLAFEN_02029 1.4e-72 flgD N Flagellar basal body rod modification protein
JOCLAFEN_02030 4e-139 flgG N Flagellar basal body rod
JOCLAFEN_02031 7.8e-57 fliL N Controls the rotational direction of flagella during chemotaxis
JOCLAFEN_02032 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
JOCLAFEN_02033 1.8e-185 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JOCLAFEN_02034 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
JOCLAFEN_02035 5.6e-110 fliZ N Flagellar biosynthesis protein, FliO
JOCLAFEN_02036 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
JOCLAFEN_02037 2e-37 fliQ N Role in flagellar biosynthesis
JOCLAFEN_02038 5.2e-131 fliR N Flagellar biosynthetic protein FliR
JOCLAFEN_02039 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOCLAFEN_02040 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JOCLAFEN_02041 3e-193 flhF N Flagellar biosynthesis regulator FlhF
JOCLAFEN_02042 1.6e-155 flhG D Belongs to the ParA family
JOCLAFEN_02043 1.3e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
JOCLAFEN_02044 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
JOCLAFEN_02045 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
JOCLAFEN_02046 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
JOCLAFEN_02047 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
JOCLAFEN_02048 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOCLAFEN_02049 1.8e-54 ylxL
JOCLAFEN_02050 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
JOCLAFEN_02051 5.3e-156 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JOCLAFEN_02052 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JOCLAFEN_02053 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JOCLAFEN_02054 2.9e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JOCLAFEN_02055 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
JOCLAFEN_02056 5.6e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
JOCLAFEN_02057 1.5e-233 rasP M zinc metalloprotease
JOCLAFEN_02058 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JOCLAFEN_02059 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOCLAFEN_02060 6.7e-81 rimP S Required for maturation of 30S ribosomal subunits
JOCLAFEN_02061 5.4e-206 nusA K Participates in both transcription termination and antitermination
JOCLAFEN_02062 3.8e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
JOCLAFEN_02063 1.8e-47 ylxQ J ribosomal protein
JOCLAFEN_02064 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JOCLAFEN_02065 3.9e-44 ylxP S protein conserved in bacteria
JOCLAFEN_02066 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JOCLAFEN_02067 4e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JOCLAFEN_02068 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JOCLAFEN_02069 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JOCLAFEN_02070 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
JOCLAFEN_02071 1.8e-181 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
JOCLAFEN_02072 1.4e-234 pepR S Belongs to the peptidase M16 family
JOCLAFEN_02073 2.6e-42 ymxH S YlmC YmxH family
JOCLAFEN_02074 1.2e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
JOCLAFEN_02075 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
JOCLAFEN_02076 1.7e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JOCLAFEN_02077 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
JOCLAFEN_02078 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JOCLAFEN_02079 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOCLAFEN_02080 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
JOCLAFEN_02081 6.3e-31 S YlzJ-like protein
JOCLAFEN_02082 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JOCLAFEN_02083 1.8e-133 ymfC K Transcriptional regulator
JOCLAFEN_02084 2.4e-229 ymfD EGP Major facilitator Superfamily
JOCLAFEN_02085 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
JOCLAFEN_02086 0.0 ydgH S drug exporters of the RND superfamily
JOCLAFEN_02087 1.2e-238 ymfF S Peptidase M16
JOCLAFEN_02088 3.7e-243 ymfH S zinc protease
JOCLAFEN_02089 6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
JOCLAFEN_02090 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
JOCLAFEN_02091 3.5e-143 ymfK S Protein of unknown function (DUF3388)
JOCLAFEN_02092 4.2e-124 ymfM S protein conserved in bacteria
JOCLAFEN_02093 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOCLAFEN_02094 8.4e-232 cinA 3.5.1.42 S Belongs to the CinA family
JOCLAFEN_02095 2.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JOCLAFEN_02096 5e-194 pbpX V Beta-lactamase
JOCLAFEN_02097 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
JOCLAFEN_02098 4.9e-153 ymdB S protein conserved in bacteria
JOCLAFEN_02099 1.2e-36 spoVS S Stage V sporulation protein S
JOCLAFEN_02100 6.6e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
JOCLAFEN_02101 8.2e-213 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JOCLAFEN_02102 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JOCLAFEN_02103 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
JOCLAFEN_02104 1.7e-88 cotE S Spore coat protein
JOCLAFEN_02105 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JOCLAFEN_02106 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JOCLAFEN_02107 1.3e-68 L Belongs to the 'phage' integrase family
JOCLAFEN_02108 9.1e-31
JOCLAFEN_02110 3.9e-130 pksB 3.1.2.6 S Polyketide biosynthesis
JOCLAFEN_02111 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOCLAFEN_02112 3.9e-184 pksD Q Acyl transferase domain
JOCLAFEN_02113 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOCLAFEN_02114 6.5e-35 acpK IQ Phosphopantetheine attachment site
JOCLAFEN_02115 2.4e-242 pksG 2.3.3.10 I synthase
JOCLAFEN_02116 2.2e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
JOCLAFEN_02117 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
JOCLAFEN_02118 0.0 rhiB IQ polyketide synthase
JOCLAFEN_02119 0.0 Q Polyketide synthase of type I
JOCLAFEN_02120 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
JOCLAFEN_02121 0.0 dhbF IQ polyketide synthase
JOCLAFEN_02122 0.0 pks13 HQ Beta-ketoacyl synthase
JOCLAFEN_02123 2.4e-231 cypA C Cytochrome P450
JOCLAFEN_02124 6.4e-78 nucB M Deoxyribonuclease NucA/NucB
JOCLAFEN_02125 3.6e-118 yoaK S Membrane
JOCLAFEN_02126 1.4e-62 ymzB
JOCLAFEN_02127 1.8e-256 aprX O Belongs to the peptidase S8 family
JOCLAFEN_02129 4.1e-127 ymaC S Replication protein
JOCLAFEN_02130 6e-79 ymaD O redox protein, regulator of disulfide bond formation
JOCLAFEN_02131 5.2e-54 ebrB P Small Multidrug Resistance protein
JOCLAFEN_02132 3.2e-47 ebrA P Small Multidrug Resistance protein
JOCLAFEN_02134 1.4e-47 ymaF S YmaF family
JOCLAFEN_02135 6.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JOCLAFEN_02136 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
JOCLAFEN_02137 8.5e-44
JOCLAFEN_02138 1.8e-20 ymzA
JOCLAFEN_02139 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
JOCLAFEN_02140 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOCLAFEN_02141 1.3e-182 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOCLAFEN_02142 2.4e-110 ymaB S MutT family
JOCLAFEN_02143 1.9e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOCLAFEN_02144 5.1e-176 spoVK O stage V sporulation protein K
JOCLAFEN_02145 7.2e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JOCLAFEN_02146 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
JOCLAFEN_02147 4.3e-68 glnR K transcriptional
JOCLAFEN_02148 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
JOCLAFEN_02149 8.2e-215 mrjp G Major royal jelly protein
JOCLAFEN_02150 9.6e-253 xynT G MFS/sugar transport protein
JOCLAFEN_02151 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JOCLAFEN_02152 1.2e-216 xylR GK ROK family
JOCLAFEN_02153 2.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
JOCLAFEN_02154 2.9e-287 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
JOCLAFEN_02155 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
JOCLAFEN_02158 5.4e-17
JOCLAFEN_02159 3.9e-187 adhP 1.1.1.1 C alcohol dehydrogenase
JOCLAFEN_02161 3.1e-144 yoaP 3.1.3.18 K YoaP-like
JOCLAFEN_02162 7.4e-100 J Acetyltransferase (GNAT) domain
JOCLAFEN_02163 8.2e-22
JOCLAFEN_02165 1.3e-119 ynaE S Domain of unknown function (DUF3885)
JOCLAFEN_02166 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOCLAFEN_02167 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
JOCLAFEN_02169 6.5e-64 2.3.1.128 J Acetyltransferase (GNAT) domain
JOCLAFEN_02170 3.5e-94 yvgO
JOCLAFEN_02172 0.0 yobO M Pectate lyase superfamily protein
JOCLAFEN_02173 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
JOCLAFEN_02174 1.5e-144 yndL S Replication protein
JOCLAFEN_02175 1.6e-07
JOCLAFEN_02176 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
JOCLAFEN_02177 2.4e-72 yndM S Protein of unknown function (DUF2512)
JOCLAFEN_02178 2.1e-12 yoaW
JOCLAFEN_02179 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOCLAFEN_02180 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
JOCLAFEN_02181 3.5e-112 yneB L resolvase
JOCLAFEN_02182 9.8e-33 ynzC S UPF0291 protein
JOCLAFEN_02183 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JOCLAFEN_02184 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
JOCLAFEN_02185 2.3e-28 yneF S UPF0154 protein
JOCLAFEN_02186 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
JOCLAFEN_02187 1.7e-125 ccdA O cytochrome c biogenesis protein
JOCLAFEN_02188 1e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
JOCLAFEN_02189 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
JOCLAFEN_02190 8.5e-75 yneK S Protein of unknown function (DUF2621)
JOCLAFEN_02191 2.9e-63 hspX O Spore coat protein
JOCLAFEN_02192 2.3e-19 sspP S Belongs to the SspP family
JOCLAFEN_02193 7.5e-15 sspO S Belongs to the SspO family
JOCLAFEN_02194 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JOCLAFEN_02195 1.4e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JOCLAFEN_02197 7.1e-18 tlp S Belongs to the Tlp family
JOCLAFEN_02198 8.3e-75 yneP S Thioesterase-like superfamily
JOCLAFEN_02199 4.4e-54 yneQ
JOCLAFEN_02200 1.3e-50 yneR S Belongs to the HesB IscA family
JOCLAFEN_02201 8.5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JOCLAFEN_02202 1.5e-68 yccU S CoA-binding protein
JOCLAFEN_02203 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOCLAFEN_02204 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOCLAFEN_02205 4.6e-13
JOCLAFEN_02206 5.1e-41 ynfC
JOCLAFEN_02207 1.6e-250 agcS E Sodium alanine symporter
JOCLAFEN_02208 1e-181 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
JOCLAFEN_02209 1.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
JOCLAFEN_02210 8.9e-113 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
JOCLAFEN_02211 7e-211 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
JOCLAFEN_02212 2e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
JOCLAFEN_02213 1.7e-182 kdgR_1 K transcriptional
JOCLAFEN_02214 2.9e-224 exuT G Sugar (and other) transporter
JOCLAFEN_02215 2.9e-156 yndG S DoxX-like family
JOCLAFEN_02216 8.9e-78 yndH S Domain of unknown function (DUF4166)
JOCLAFEN_02217 4.5e-302 yndJ S YndJ-like protein
JOCLAFEN_02218 3.3e-82 S Protein of unknown function (DUF1430)
JOCLAFEN_02219 8.8e-65 V ABC transporter
JOCLAFEN_02221 2.6e-216 S Platelet-activating factor acetylhydrolase, isoform II
JOCLAFEN_02222 1.1e-289 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
JOCLAFEN_02223 2.8e-51 S Domain of unknown function (DUF4870)
JOCLAFEN_02224 2e-234 T PhoQ Sensor
JOCLAFEN_02225 2.2e-128 T Transcriptional regulatory protein, C terminal
JOCLAFEN_02226 4.3e-252 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
JOCLAFEN_02227 7e-289 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
JOCLAFEN_02228 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02229 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02230 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02231 1.3e-221 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOCLAFEN_02233 5.8e-138 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JOCLAFEN_02234 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JOCLAFEN_02235 8.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOCLAFEN_02236 2.1e-255 yxjC EG COG2610 H gluconate symporter and related permeases
JOCLAFEN_02237 6.2e-224 bioI 1.14.14.46 C Cytochrome P450
JOCLAFEN_02238 8.2e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JOCLAFEN_02239 3e-130 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JOCLAFEN_02240 5.6e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
JOCLAFEN_02241 1.2e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
JOCLAFEN_02242 3.9e-147 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
JOCLAFEN_02243 3.7e-72 yngA S membrane
JOCLAFEN_02244 3.8e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOCLAFEN_02245 3.2e-104 yngC S SNARE associated Golgi protein
JOCLAFEN_02246 1.4e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JOCLAFEN_02247 5.2e-139 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
JOCLAFEN_02248 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
JOCLAFEN_02249 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
JOCLAFEN_02250 9.3e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
JOCLAFEN_02251 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JOCLAFEN_02252 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
JOCLAFEN_02253 2e-304 yngK T Glycosyl hydrolase-like 10
JOCLAFEN_02254 4.1e-65 yngL S Protein of unknown function (DUF1360)
JOCLAFEN_02255 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
JOCLAFEN_02256 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02257 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02258 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02259 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02260 2.7e-269 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
JOCLAFEN_02261 1.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
JOCLAFEN_02262 2.7e-247 yoeA V MATE efflux family protein
JOCLAFEN_02263 2.2e-96 yoeB S IseA DL-endopeptidase inhibitor
JOCLAFEN_02265 2.2e-96 L Integrase
JOCLAFEN_02266 1.8e-34 yoeD G Helix-turn-helix domain
JOCLAFEN_02267 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
JOCLAFEN_02268 1.2e-200 ybcL EGP Major facilitator Superfamily
JOCLAFEN_02269 6.7e-50 ybzH K Helix-turn-helix domain
JOCLAFEN_02270 6.1e-15 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOCLAFEN_02271 2.8e-157 gltR1 K Transcriptional regulator
JOCLAFEN_02272 7.1e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JOCLAFEN_02274 1.7e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
JOCLAFEN_02275 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
JOCLAFEN_02276 8.7e-146 gltC K Transcriptional regulator
JOCLAFEN_02277 2.8e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JOCLAFEN_02278 2e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOCLAFEN_02279 9.5e-62 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
JOCLAFEN_02280 6.8e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
JOCLAFEN_02281 4.8e-40 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JOCLAFEN_02282 2.7e-140 yoxB
JOCLAFEN_02283 1.9e-204 yoaB EGP Major facilitator Superfamily
JOCLAFEN_02284 1e-273 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
JOCLAFEN_02285 4.3e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOCLAFEN_02286 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOCLAFEN_02288 1e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
JOCLAFEN_02289 1.6e-45
JOCLAFEN_02290 1.5e-85 S SMI1-KNR4 cell-wall
JOCLAFEN_02291 0.0 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JOCLAFEN_02292 1.9e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
JOCLAFEN_02293 3.5e-134 yobQ K helix_turn_helix, arabinose operon control protein
JOCLAFEN_02294 4.8e-94 yobS K Transcriptional regulator
JOCLAFEN_02295 1.9e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
JOCLAFEN_02296 5.5e-92 yobW
JOCLAFEN_02297 3.4e-55 czrA K transcriptional
JOCLAFEN_02298 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
JOCLAFEN_02299 2.8e-91 yozB S membrane
JOCLAFEN_02300 1.5e-141 yocB J Protein required for attachment to host cells
JOCLAFEN_02301 1.9e-94 yocC
JOCLAFEN_02302 5.5e-186 yocD 3.4.17.13 V peptidase S66
JOCLAFEN_02304 1e-114 yocH CBM50 M COG1388 FOG LysM repeat
JOCLAFEN_02305 0.0 recQ 3.6.4.12 L DNA helicase
JOCLAFEN_02306 5.3e-110 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JOCLAFEN_02308 9.5e-54 dksA T general stress protein
JOCLAFEN_02309 7.8e-10 yocL
JOCLAFEN_02310 1.7e-08
JOCLAFEN_02311 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
JOCLAFEN_02312 3.8e-44 yozN
JOCLAFEN_02313 8.5e-37 yocN
JOCLAFEN_02314 2.4e-56 yozO S Bacterial PH domain
JOCLAFEN_02316 1.6e-31 yozC
JOCLAFEN_02317 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
JOCLAFEN_02318 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
JOCLAFEN_02319 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
JOCLAFEN_02320 3.9e-235 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
JOCLAFEN_02321 2.7e-161 yocS S -transporter
JOCLAFEN_02322 2.6e-143 S Metallo-beta-lactamase superfamily
JOCLAFEN_02323 1.9e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
JOCLAFEN_02324 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
JOCLAFEN_02325 0.0 yojO P Von Willebrand factor
JOCLAFEN_02326 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
JOCLAFEN_02327 2e-111 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JOCLAFEN_02328 9.5e-228 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
JOCLAFEN_02329 1.1e-225 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
JOCLAFEN_02330 7.4e-112 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOCLAFEN_02332 1e-243 norM V Multidrug efflux pump
JOCLAFEN_02333 4.5e-152 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOCLAFEN_02334 2.5e-126 yojG S deacetylase
JOCLAFEN_02335 3.7e-60 yojF S Protein of unknown function (DUF1806)
JOCLAFEN_02336 4.9e-23
JOCLAFEN_02337 3.5e-163 rarD S -transporter
JOCLAFEN_02338 2.5e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
JOCLAFEN_02340 1e-66 yodA S tautomerase
JOCLAFEN_02341 3.9e-68 yoaQ S Evidence 4 Homologs of previously reported genes of
JOCLAFEN_02342 1.4e-56 yodB K transcriptional
JOCLAFEN_02343 4.5e-106 yodC C nitroreductase
JOCLAFEN_02344 2.7e-111 mhqD S Carboxylesterase
JOCLAFEN_02345 3.5e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
JOCLAFEN_02346 1.4e-19 S Protein of unknown function (DUF3311)
JOCLAFEN_02347 3e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOCLAFEN_02349 1.6e-49 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOCLAFEN_02350 1.8e-254 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
JOCLAFEN_02351 2.8e-128 yodH Q Methyltransferase
JOCLAFEN_02352 1.1e-34 yodI
JOCLAFEN_02353 6.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
JOCLAFEN_02354 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JOCLAFEN_02356 3.3e-55 yodL S YodL-like
JOCLAFEN_02357 5.2e-102 yodM 3.6.1.27 I Acid phosphatase homologues
JOCLAFEN_02358 6.2e-24 yozD S YozD-like protein
JOCLAFEN_02360 1.7e-125 yodN
JOCLAFEN_02361 1.5e-35 yozE S Belongs to the UPF0346 family
JOCLAFEN_02362 7.8e-45 yokU S YokU-like protein, putative antitoxin
JOCLAFEN_02363 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
JOCLAFEN_02364 1.2e-157 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
JOCLAFEN_02365 1.9e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
JOCLAFEN_02366 6.1e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
JOCLAFEN_02367 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JOCLAFEN_02368 6.8e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOCLAFEN_02369 2.6e-19 yosT L Bacterial transcription activator, effector binding domain
JOCLAFEN_02371 8.3e-145 yiiD K acetyltransferase
JOCLAFEN_02372 7.2e-247 cgeD M maturation of the outermost layer of the spore
JOCLAFEN_02373 1.1e-41 cgeC
JOCLAFEN_02374 3.3e-50 cgeA
JOCLAFEN_02375 1.2e-180 cgeB S Spore maturation protein
JOCLAFEN_02376 3.1e-220 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
JOCLAFEN_02377 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
JOCLAFEN_02382 5.3e-193 S aspartate phosphatase
JOCLAFEN_02384 2.8e-17 3.4.24.40 S amine dehydrogenase activity
JOCLAFEN_02387 2e-61 S SMI1-KNR4 cell-wall
JOCLAFEN_02388 2.1e-143 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
JOCLAFEN_02389 2.3e-139 mta K transcriptional
JOCLAFEN_02390 6.2e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
JOCLAFEN_02391 8.8e-223 ywbD 2.1.1.191 J Methyltransferase
JOCLAFEN_02392 9e-68 ywbC 4.4.1.5 E glyoxalase
JOCLAFEN_02393 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOCLAFEN_02394 1.2e-263 epr 3.4.21.62 O Belongs to the peptidase S8 family
JOCLAFEN_02395 9.7e-163 gspA M General stress
JOCLAFEN_02396 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
JOCLAFEN_02397 3.8e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
JOCLAFEN_02398 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
JOCLAFEN_02399 4.2e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02400 3.7e-229 dltB M membrane protein involved in D-alanine export
JOCLAFEN_02401 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02402 3.7e-229 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JOCLAFEN_02403 1.3e-204 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JOCLAFEN_02404 4.6e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JOCLAFEN_02405 7.8e-52 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOCLAFEN_02406 2.2e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOCLAFEN_02407 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
JOCLAFEN_02408 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
JOCLAFEN_02409 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JOCLAFEN_02410 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_02411 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_02412 4e-167 cbrA3 P Periplasmic binding protein
JOCLAFEN_02413 2.7e-58 arsR K transcriptional
JOCLAFEN_02414 2.2e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JOCLAFEN_02415 6.9e-50 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOCLAFEN_02416 9.1e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
JOCLAFEN_02417 3.2e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOCLAFEN_02418 1.3e-286 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOCLAFEN_02419 5.1e-167 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
JOCLAFEN_02420 1.2e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
JOCLAFEN_02421 7.8e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
JOCLAFEN_02422 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JOCLAFEN_02423 1.9e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
JOCLAFEN_02424 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
JOCLAFEN_02425 2e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JOCLAFEN_02426 1.5e-292 cydD V ATP-binding protein
JOCLAFEN_02427 2.4e-311 cydD V ATP-binding
JOCLAFEN_02428 1.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
JOCLAFEN_02429 2.6e-266 cydA 1.10.3.14 C oxidase, subunit
JOCLAFEN_02430 4.5e-215 cimH C COG3493 Na citrate symporter
JOCLAFEN_02431 1.6e-157 yxkH G Polysaccharide deacetylase
JOCLAFEN_02432 2.6e-205 msmK P Belongs to the ABC transporter superfamily
JOCLAFEN_02433 1.2e-168 lrp QT PucR C-terminal helix-turn-helix domain
JOCLAFEN_02434 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOCLAFEN_02435 3.8e-87 yxkC S Domain of unknown function (DUF4352)
JOCLAFEN_02436 1.9e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JOCLAFEN_02437 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JOCLAFEN_02440 4.5e-69 yxjI S LURP-one-related
JOCLAFEN_02441 1.3e-218 yxjG 2.1.1.14 E Methionine synthase
JOCLAFEN_02442 1e-162 rlmA 2.1.1.187 Q Methyltransferase domain
JOCLAFEN_02443 3.8e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOCLAFEN_02444 2.7e-75 T Domain of unknown function (DUF4163)
JOCLAFEN_02445 1.4e-50 yxiS
JOCLAFEN_02446 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
JOCLAFEN_02447 1.1e-221 citH C Citrate transporter
JOCLAFEN_02448 1.5e-143 exoK GH16 M licheninase activity
JOCLAFEN_02449 2e-149 licT K transcriptional antiterminator
JOCLAFEN_02450 9.3e-223 yxiO S COG2270 Permeases of the major facilitator superfamily
JOCLAFEN_02451 1.5e-253 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
JOCLAFEN_02452 1e-115
JOCLAFEN_02453 2.6e-25
JOCLAFEN_02454 8.3e-216 S Uncharacterised protein conserved in bacteria (DUF2326)
JOCLAFEN_02455 8.9e-93 S Protein of unknown function (DUF4240)
JOCLAFEN_02456 4.9e-121
JOCLAFEN_02457 1.3e-13
JOCLAFEN_02458 0.0 wapA M COG3209 Rhs family protein
JOCLAFEN_02459 5.9e-202 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
JOCLAFEN_02460 1.1e-145 yxxF EG EamA-like transporter family
JOCLAFEN_02461 9.8e-74 yxiE T Belongs to the universal stress protein A family
JOCLAFEN_02462 6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOCLAFEN_02463 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOCLAFEN_02464 0.0 L HKD family nuclease
JOCLAFEN_02465 3.1e-60 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
JOCLAFEN_02466 1.9e-280 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
JOCLAFEN_02467 3.8e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
JOCLAFEN_02468 1.5e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
JOCLAFEN_02469 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JOCLAFEN_02470 1.4e-237 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
JOCLAFEN_02471 4.5e-177 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
JOCLAFEN_02472 2.9e-252 lysP E amino acid
JOCLAFEN_02473 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
JOCLAFEN_02474 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JOCLAFEN_02475 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JOCLAFEN_02476 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
JOCLAFEN_02477 4e-150 yidA S hydrolases of the HAD superfamily
JOCLAFEN_02480 6.4e-13 yxeE
JOCLAFEN_02481 3.2e-22 yxeD
JOCLAFEN_02482 6e-35
JOCLAFEN_02483 5.4e-178 fhuD P Periplasmic binding protein
JOCLAFEN_02484 1.3e-57 yxeA S Protein of unknown function (DUF1093)
JOCLAFEN_02485 0.0 yxdM V ABC transporter (permease)
JOCLAFEN_02486 5.5e-141 yxdL V ABC transporter, ATP-binding protein
JOCLAFEN_02487 3.9e-176 T PhoQ Sensor
JOCLAFEN_02488 1.8e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_02489 6.4e-276 T Histidine kinase
JOCLAFEN_02490 2.6e-137 T Transcriptional regulator
JOCLAFEN_02491 3.2e-164 bcrA V ABC transporter, ATP-binding protein
JOCLAFEN_02492 1e-131 S permease
JOCLAFEN_02493 9.3e-130 S ABC-2 family transporter protein
JOCLAFEN_02495 5.6e-14 KT Transcriptional regulatory protein, C terminal
JOCLAFEN_02496 8.7e-38 4.1.1.36, 6.3.2.5 H Flavoprotein
JOCLAFEN_02497 1.5e-179 V Domain of unknown function (DUF4135)
JOCLAFEN_02498 5.6e-130 lanT 3.6.3.27 V TIGRFAM NHLM bacteriocin system ABC transporter, peptidase ATP-binding protein
JOCLAFEN_02499 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
JOCLAFEN_02500 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
JOCLAFEN_02501 1.1e-166 iolH G Xylose isomerase-like TIM barrel
JOCLAFEN_02502 1.6e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
JOCLAFEN_02503 1e-232 iolF EGP Major facilitator Superfamily
JOCLAFEN_02504 2.5e-177 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
JOCLAFEN_02505 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
JOCLAFEN_02506 5.7e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
JOCLAFEN_02507 2.9e-156 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
JOCLAFEN_02508 1.2e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOCLAFEN_02509 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
JOCLAFEN_02510 2.4e-175 iolS C Aldo keto reductase
JOCLAFEN_02511 6.7e-246 csbC EGP Major facilitator Superfamily
JOCLAFEN_02512 0.0 htpG O Molecular chaperone. Has ATPase activity
JOCLAFEN_02514 2.1e-151 IQ Enoyl-(Acyl carrier protein) reductase
JOCLAFEN_02515 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
JOCLAFEN_02516 1.2e-200 desK 2.7.13.3 T Histidine kinase
JOCLAFEN_02517 3.4e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JOCLAFEN_02518 3.5e-216 yxbF K Bacterial regulatory proteins, tetR family
JOCLAFEN_02519 9.6e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
JOCLAFEN_02520 2e-140 S PQQ-like domain
JOCLAFEN_02521 1.7e-59 S Family of unknown function (DUF5391)
JOCLAFEN_02522 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
JOCLAFEN_02523 4.5e-203 EGP Major facilitator Superfamily
JOCLAFEN_02524 1.5e-74 yxaI S membrane protein domain
JOCLAFEN_02525 6.2e-128 E Ring-cleavage extradiol dioxygenase
JOCLAFEN_02526 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
JOCLAFEN_02527 2.3e-287 ahpF O Alkyl hydroperoxide reductase
JOCLAFEN_02528 3.8e-229 XK27_00240 S Fic/DOC family
JOCLAFEN_02529 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
JOCLAFEN_02530 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
JOCLAFEN_02531 1.1e-85 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
JOCLAFEN_02532 8.1e-154 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
JOCLAFEN_02533 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
JOCLAFEN_02534 2.6e-85 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
JOCLAFEN_02535 1.8e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
JOCLAFEN_02536 2.3e-179 S Fusaric acid resistance protein-like
JOCLAFEN_02537 0.0 T Nacht domain
JOCLAFEN_02538 1.5e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JOCLAFEN_02539 7.9e-08 S YyzF-like protein
JOCLAFEN_02541 3.5e-216 yycP
JOCLAFEN_02542 7e-133 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JOCLAFEN_02543 4.8e-182 C oxidoreductases (related to aryl-alcohol dehydrogenases)
JOCLAFEN_02544 2.9e-84 yycN 2.3.1.128 K Acetyltransferase
JOCLAFEN_02546 1.5e-200 S Histidine kinase
JOCLAFEN_02547 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
JOCLAFEN_02548 1.2e-258 rocE E amino acid
JOCLAFEN_02549 5.9e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
JOCLAFEN_02550 5.5e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
JOCLAFEN_02551 1.3e-42 sdpR K transcriptional
JOCLAFEN_02552 2.2e-260 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
JOCLAFEN_02553 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
JOCLAFEN_02554 2.5e-305 S ABC transporter
JOCLAFEN_02555 3.4e-198 S Major Facilitator Superfamily
JOCLAFEN_02556 6.3e-262
JOCLAFEN_02557 1.9e-189 2.7.7.73, 2.7.7.80 H ThiF family
JOCLAFEN_02558 1.1e-251 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
JOCLAFEN_02559 4.7e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_02560 1.3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JOCLAFEN_02561 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
JOCLAFEN_02562 6.4e-151 yycI S protein conserved in bacteria
JOCLAFEN_02563 2.3e-259 yycH S protein conserved in bacteria
JOCLAFEN_02564 0.0 vicK 2.7.13.3 T Histidine kinase
JOCLAFEN_02565 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_02570 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JOCLAFEN_02571 9.1e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOCLAFEN_02572 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JOCLAFEN_02573 1.4e-27 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
JOCLAFEN_02575 3.5e-17 yycC K YycC-like protein
JOCLAFEN_02576 8.7e-240 M Glycosyltransferase Family 4
JOCLAFEN_02577 1.8e-203 S Ecdysteroid kinase
JOCLAFEN_02578 2.2e-234 S Carbamoyl-phosphate synthase L chain, ATP binding domain
JOCLAFEN_02579 9.6e-242 M Glycosyltransferase Family 4
JOCLAFEN_02580 9.2e-121 S GlcNAc-PI de-N-acetylase
JOCLAFEN_02581 3.8e-122 KLT COG0515 Serine threonine protein kinase
JOCLAFEN_02582 1.4e-72 rplI J binds to the 23S rRNA
JOCLAFEN_02583 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JOCLAFEN_02584 1.6e-158 yybS S membrane
JOCLAFEN_02586 6.5e-85 cotF M Spore coat protein
JOCLAFEN_02587 2.8e-66 ydeP3 K Transcriptional regulator
JOCLAFEN_02588 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
JOCLAFEN_02589 4.4e-155 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JOCLAFEN_02590 2.2e-273 sacB 2.4.1.10 GH68 M levansucrase activity
JOCLAFEN_02591 8.9e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
JOCLAFEN_02592 1.8e-116 K FCD domain
JOCLAFEN_02593 9.1e-76 dinB S PFAM DinB family protein
JOCLAFEN_02594 8.9e-162 G Major Facilitator Superfamily
JOCLAFEN_02595 1.3e-159 yfiE K LysR substrate binding domain
JOCLAFEN_02596 1.1e-100 E LysE type translocator
JOCLAFEN_02597 2.9e-55 ypaA S Protein of unknown function (DUF1304)
JOCLAFEN_02598 1.6e-114 drgA C nitroreductase
JOCLAFEN_02599 3.2e-69 ydgJ K Winged helix DNA-binding domain
JOCLAFEN_02600 8.7e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
JOCLAFEN_02601 9.6e-77 yybA 2.3.1.57 K transcriptional
JOCLAFEN_02602 1.7e-75 yjcF S Acetyltransferase (GNAT) domain
JOCLAFEN_02603 2.6e-163 eaeH M Domain of Unknown Function (DUF1259)
JOCLAFEN_02604 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
JOCLAFEN_02605 4.9e-165 K Transcriptional regulator
JOCLAFEN_02606 4.9e-58 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JOCLAFEN_02607 2.4e-47 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
JOCLAFEN_02608 2.3e-249 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOCLAFEN_02609 5.2e-130 ydfC EG EamA-like transporter family
JOCLAFEN_02610 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
JOCLAFEN_02611 7e-164 yyaK S CAAX protease self-immunity
JOCLAFEN_02612 3.4e-247 ydjK G Sugar (and other) transporter
JOCLAFEN_02613 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOCLAFEN_02614 1.3e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
JOCLAFEN_02615 1.6e-145 xth 3.1.11.2 L exodeoxyribonuclease III
JOCLAFEN_02616 2.6e-100 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOCLAFEN_02617 3.7e-105 adaA 3.2.2.21 K Transcriptional regulator
JOCLAFEN_02618 1.1e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JOCLAFEN_02619 4.2e-68 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JOCLAFEN_02620 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
JOCLAFEN_02621 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JOCLAFEN_02622 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOCLAFEN_02623 2.3e-33 yyzM S protein conserved in bacteria
JOCLAFEN_02624 2.4e-176 yyaD S Membrane
JOCLAFEN_02625 6.9e-84 4.2.1.103 K FR47-like protein
JOCLAFEN_02626 6.2e-111 yyaC S Sporulation protein YyaC
JOCLAFEN_02627 7.9e-149 spo0J K Belongs to the ParB family
JOCLAFEN_02628 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
JOCLAFEN_02629 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
JOCLAFEN_02630 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
JOCLAFEN_02631 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JOCLAFEN_02632 2e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JOCLAFEN_02633 4.2e-110 jag S single-stranded nucleic acid binding R3H
JOCLAFEN_02634 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOCLAFEN_02635 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JOCLAFEN_02636 5.1e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JOCLAFEN_02637 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JOCLAFEN_02638 2.4e-33 yaaA S S4 domain
JOCLAFEN_02639 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JOCLAFEN_02640 8.1e-38 yaaB S Domain of unknown function (DUF370)
JOCLAFEN_02641 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOCLAFEN_02642 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOCLAFEN_02643 4.4e-77 yclD
JOCLAFEN_02644 2e-38 bsdD 4.1.1.61 S response to toxic substance
JOCLAFEN_02645 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
JOCLAFEN_02646 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
JOCLAFEN_02647 4.7e-157 bsdA K LysR substrate binding domain
JOCLAFEN_02648 5.1e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
JOCLAFEN_02649 6.4e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
JOCLAFEN_02650 1.4e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOCLAFEN_02651 4.1e-110 yczE S membrane
JOCLAFEN_02652 4.5e-131 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
JOCLAFEN_02653 2.4e-245 ycxD K GntR family transcriptional regulator
JOCLAFEN_02654 5e-168 ycxC EG EamA-like transporter family
JOCLAFEN_02655 3.8e-64 S YcxB-like protein
JOCLAFEN_02656 3.6e-249 bamJ E Aminotransferase class I and II
JOCLAFEN_02657 5.8e-140 srfAD Q thioesterase
JOCLAFEN_02658 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
JOCLAFEN_02659 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02660 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOCLAFEN_02661 6.3e-63 hxlR K transcriptional
JOCLAFEN_02662 1.2e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
JOCLAFEN_02663 1.3e-94 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
JOCLAFEN_02664 1.2e-76 nucA M Deoxyribonuclease NucA/NucB
JOCLAFEN_02665 1.8e-66 nin S Competence protein J (ComJ)
JOCLAFEN_02666 6.1e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOCLAFEN_02667 2.2e-51 S Protein of unknown function (DUF2680)
JOCLAFEN_02668 1.2e-73 yckC S membrane
JOCLAFEN_02669 2.8e-185 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JOCLAFEN_02670 3.9e-226 yciC S GTPases (G3E family)
JOCLAFEN_02671 6.4e-221 nasA P COG2223 Nitrate nitrite transporter
JOCLAFEN_02672 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
JOCLAFEN_02673 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
JOCLAFEN_02674 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JOCLAFEN_02675 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
JOCLAFEN_02676 8.6e-281 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
JOCLAFEN_02677 1.7e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JOCLAFEN_02678 4.7e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
JOCLAFEN_02679 6.4e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOCLAFEN_02680 1.8e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
JOCLAFEN_02681 2.3e-170 ycgM E Proline dehydrogenase
JOCLAFEN_02682 1.7e-145 ycgL S Predicted nucleotidyltransferase
JOCLAFEN_02683 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
JOCLAFEN_02684 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JOCLAFEN_02685 5.2e-232 G COG0477 Permeases of the major facilitator superfamily
JOCLAFEN_02686 2.1e-148 4.2.1.118 G Xylose isomerase-like TIM barrel
JOCLAFEN_02687 2.3e-107 tmrB S AAA domain
JOCLAFEN_02689 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JOCLAFEN_02690 7.6e-114 ycgI S Domain of unknown function (DUF1989)
JOCLAFEN_02691 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
JOCLAFEN_02692 5.8e-151 yqcI S YqcI/YcgG family
JOCLAFEN_02693 5.2e-113 ycgF E Lysine exporter protein LysE YggA
JOCLAFEN_02694 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
JOCLAFEN_02695 2.8e-261 mdr EGP Major facilitator Superfamily
JOCLAFEN_02696 3.7e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JOCLAFEN_02697 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
JOCLAFEN_02698 5.9e-80 ycgB
JOCLAFEN_02699 3.1e-230 ycgA S Membrane
JOCLAFEN_02700 3e-212 amhX S amidohydrolase
JOCLAFEN_02701 3.1e-164 opuAC E glycine betaine
JOCLAFEN_02702 1.6e-138 opuAB P glycine betaine
JOCLAFEN_02703 3.9e-229 proV 3.6.3.32 E glycine betaine
JOCLAFEN_02704 2.4e-215 naiP P Uncharacterised MFS-type transporter YbfB
JOCLAFEN_02705 8.7e-193 yceH P Belongs to the TelA family
JOCLAFEN_02706 0.0 yceG S Putative component of 'biosynthetic module'
JOCLAFEN_02707 9.7e-138 terC P Protein of unknown function (DUF475)
JOCLAFEN_02708 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
JOCLAFEN_02709 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
JOCLAFEN_02710 6.2e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
JOCLAFEN_02711 1.6e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOCLAFEN_02712 1.5e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
JOCLAFEN_02713 7.2e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
JOCLAFEN_02714 3.5e-164 adcA P Belongs to the bacterial solute-binding protein 9 family
JOCLAFEN_02715 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
JOCLAFEN_02716 3.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
JOCLAFEN_02717 4.6e-189 S response regulator aspartate phosphatase
JOCLAFEN_02718 2.4e-92 cwlK M D-alanyl-D-alanine carboxypeptidase
JOCLAFEN_02719 1.1e-266 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
JOCLAFEN_02720 1.6e-260 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
JOCLAFEN_02721 1.6e-177 ycdA S Domain of unknown function (DUF5105)
JOCLAFEN_02722 1.2e-171 yccK C Aldo keto reductase
JOCLAFEN_02723 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
JOCLAFEN_02724 3.4e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
JOCLAFEN_02725 4.4e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
JOCLAFEN_02726 1.2e-100 yxaF K Transcriptional regulator
JOCLAFEN_02727 1.1e-238 lmrB EGP the major facilitator superfamily
JOCLAFEN_02728 2.9e-207 ycbU E Selenocysteine lyase
JOCLAFEN_02729 1.1e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JOCLAFEN_02730 6.8e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOCLAFEN_02731 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JOCLAFEN_02732 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
JOCLAFEN_02733 5.1e-80 sleB 3.5.1.28 M Cell wall
JOCLAFEN_02734 5.6e-62 ycbP S Protein of unknown function (DUF2512)
JOCLAFEN_02735 1.6e-55 traF CO Thioredoxin
JOCLAFEN_02736 1.5e-62 mhqP S DoxX
JOCLAFEN_02737 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
JOCLAFEN_02738 4e-110 ydfN C nitroreductase
JOCLAFEN_02739 1.2e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOCLAFEN_02740 1e-21 L Transposase
JOCLAFEN_02741 2.7e-29 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
JOCLAFEN_02742 8.9e-37 ycbJ S Macrolide 2'-phosphotransferase
JOCLAFEN_02743 1.9e-172 glnL T Regulator
JOCLAFEN_02744 4.5e-212 phoQ 2.7.13.3 T Histidine kinase
JOCLAFEN_02745 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
JOCLAFEN_02746 9.3e-259 agcS E Sodium alanine symporter
JOCLAFEN_02747 5.1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
JOCLAFEN_02748 6.1e-258 mmuP E amino acid
JOCLAFEN_02749 5.5e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
JOCLAFEN_02750 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOCLAFEN_02751 5e-192 yceA S Belongs to the UPF0176 family
JOCLAFEN_02752 1.2e-42 ybfN
JOCLAFEN_02753 6.6e-153 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
JOCLAFEN_02754 1.9e-86 ybfM S SNARE associated Golgi protein
JOCLAFEN_02755 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOCLAFEN_02756 1.1e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JOCLAFEN_02757 3.9e-201 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
JOCLAFEN_02758 1.2e-82 K Helix-turn-helix XRE-family like proteins
JOCLAFEN_02759 1.3e-30
JOCLAFEN_02760 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
JOCLAFEN_02762 1.1e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
JOCLAFEN_02763 1.3e-16 S Protein of unknown function (DUF2651)
JOCLAFEN_02764 1.7e-259 glpT G -transporter
JOCLAFEN_02765 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
JOCLAFEN_02766 3.4e-15 S Protein of unknown function (DUF2651)
JOCLAFEN_02767 3e-53
JOCLAFEN_02768 2.4e-45 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JOCLAFEN_02769 3.3e-292 ybeC E amino acid
JOCLAFEN_02770 9.2e-40 ybyB
JOCLAFEN_02771 1.6e-107 yqeB
JOCLAFEN_02772 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
JOCLAFEN_02773 9.1e-78 S Domain of unknown function (DUF4879)
JOCLAFEN_02774 4.6e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
JOCLAFEN_02775 0.0 Q TIGRFAM amino acid adenylation domain
JOCLAFEN_02776 3.1e-103 Q Flavin containing amine oxidoreductase
JOCLAFEN_02777 0.0 Q Polyketide synthase modules and related proteins
JOCLAFEN_02778 0.0 Q Beta-ketoacyl synthase
JOCLAFEN_02779 6e-121 fabD 2.3.1.39 I PFAM Acyl transferase
JOCLAFEN_02780 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
JOCLAFEN_02781 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
JOCLAFEN_02782 3.6e-59 bacT Q Thioesterase domain
JOCLAFEN_02783 4.4e-14
JOCLAFEN_02784 6e-123 V ABC-2 type transporter
JOCLAFEN_02785 2.3e-146 V ABC-2 type transporter
JOCLAFEN_02786 3.5e-134 V ABC transporter, ATP-binding protein
JOCLAFEN_02787 4.9e-82 KT helix_turn_helix, Lux Regulon
JOCLAFEN_02788 1.8e-103 T Histidine kinase
JOCLAFEN_02789 1.1e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JOCLAFEN_02790 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
JOCLAFEN_02791 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
JOCLAFEN_02792 2e-51 S LrgA family
JOCLAFEN_02793 1e-93 yxaC M effector of murein hydrolase
JOCLAFEN_02794 1.2e-162 dkgB S Aldo/keto reductase family
JOCLAFEN_02795 5.4e-132 ybdO S Domain of unknown function (DUF4885)
JOCLAFEN_02796 1.2e-99 ybdN
JOCLAFEN_02797 2.9e-106 S ABC-2 family transporter protein
JOCLAFEN_02798 3.8e-154 V ATPases associated with a variety of cellular activities
JOCLAFEN_02799 1.1e-26 CP_0264 3.2.2.10 S cytokinin biosynthetic process
JOCLAFEN_02800 6.2e-215 S Peptidase C14 caspase catalytic subunit p20
JOCLAFEN_02801 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JOCLAFEN_02802 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOCLAFEN_02803 1.3e-223 ybbR S protein conserved in bacteria
JOCLAFEN_02804 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOCLAFEN_02805 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
JOCLAFEN_02806 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
JOCLAFEN_02812 2.3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
JOCLAFEN_02813 2.6e-85 ybbJ J acetyltransferase
JOCLAFEN_02814 3.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JOCLAFEN_02815 3.9e-238 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOCLAFEN_02816 2.3e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
JOCLAFEN_02817 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
JOCLAFEN_02818 3.5e-238 ybbC 3.2.1.52 S protein conserved in bacteria
JOCLAFEN_02819 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
JOCLAFEN_02820 2e-172 feuA P Iron-uptake system-binding protein
JOCLAFEN_02821 1.4e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_02822 6.7e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_02823 6.8e-112 ybbA S Putative esterase
JOCLAFEN_02824 8.2e-174 ybaS 1.1.1.58 S Na -dependent transporter
JOCLAFEN_02825 1.5e-224 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
JOCLAFEN_02826 9.9e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
JOCLAFEN_02827 8.8e-181 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
JOCLAFEN_02828 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOCLAFEN_02829 5e-221 glcP G Major Facilitator Superfamily
JOCLAFEN_02830 0.0 pksJ Q Polyketide synthase of type I
JOCLAFEN_02831 0.0 pfaA Q Polyketide synthase of type I
JOCLAFEN_02832 0.0 Q Polyketide synthase of type I
JOCLAFEN_02833 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JOCLAFEN_02834 8e-221 eryK 1.14.13.154 C Cytochrome P450
JOCLAFEN_02835 2.9e-240 pksG 2.3.3.10 I synthase
JOCLAFEN_02836 3.1e-133 pksI I Belongs to the enoyl-CoA hydratase isomerase family
JOCLAFEN_02837 1.1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOCLAFEN_02838 2.9e-176 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
JOCLAFEN_02839 1.9e-141 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
JOCLAFEN_02840 8.7e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
JOCLAFEN_02841 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
JOCLAFEN_02842 1.5e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOCLAFEN_02844 4.9e-188 yueF S transporter activity
JOCLAFEN_02846 2.9e-57 S YolD-like protein
JOCLAFEN_02847 1.9e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOCLAFEN_02848 6.6e-89 yqjY K acetyltransferase
JOCLAFEN_02849 1.6e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
JOCLAFEN_02850 2.8e-179 yqkA K GrpB protein
JOCLAFEN_02851 7.7e-61 yqkB S Belongs to the HesB IscA family
JOCLAFEN_02852 3.2e-39 yqkC S Protein of unknown function (DUF2552)
JOCLAFEN_02853 3.9e-178 yqkD S COG1073 Hydrolases of the alpha beta superfamily
JOCLAFEN_02855 1.8e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
JOCLAFEN_02857 1.8e-72 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
JOCLAFEN_02858 2.4e-220 yqxK 3.6.4.12 L DNA helicase
JOCLAFEN_02859 3e-57 ansR K Transcriptional regulator
JOCLAFEN_02860 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
JOCLAFEN_02861 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
JOCLAFEN_02862 5.5e-240 mleN C Na H antiporter
JOCLAFEN_02863 7.7e-244 mleA 1.1.1.38 C malic enzyme
JOCLAFEN_02864 5.7e-22
JOCLAFEN_02865 1.7e-34 yqkK
JOCLAFEN_02867 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
JOCLAFEN_02868 1.9e-80 fur P Belongs to the Fur family
JOCLAFEN_02869 3.7e-37 S Protein of unknown function (DUF4227)
JOCLAFEN_02870 1.7e-165 xerD L recombinase XerD
JOCLAFEN_02871 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JOCLAFEN_02872 4.5e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JOCLAFEN_02873 4.3e-214 dacF 3.4.16.4 M Belongs to the peptidase S11 family
JOCLAFEN_02874 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
JOCLAFEN_02875 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
JOCLAFEN_02876 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOCLAFEN_02877 3.7e-111 spoVAA S Stage V sporulation protein AA
JOCLAFEN_02878 3e-60 spoVAB S Stage V sporulation protein AB
JOCLAFEN_02879 2.1e-79 spoVAC S stage V sporulation protein AC
JOCLAFEN_02880 9.3e-189 spoVAD I Stage V sporulation protein AD
JOCLAFEN_02881 3.8e-57 spoVAEB S stage V sporulation protein
JOCLAFEN_02882 1.8e-110 spoVAEA S stage V sporulation protein
JOCLAFEN_02883 1.4e-270 spoVAF EG Stage V sporulation protein AF
JOCLAFEN_02884 2.3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
JOCLAFEN_02885 6e-155 ypuA S Secreted protein
JOCLAFEN_02886 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JOCLAFEN_02887 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
JOCLAFEN_02888 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
JOCLAFEN_02889 1.7e-49 ypuD
JOCLAFEN_02890 7.3e-211 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOCLAFEN_02891 2.9e-111 ribE 2.5.1.9 H Riboflavin synthase
JOCLAFEN_02892 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JOCLAFEN_02893 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JOCLAFEN_02894 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOCLAFEN_02895 2.9e-93 ypuF S Domain of unknown function (DUF309)
JOCLAFEN_02897 2.1e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JOCLAFEN_02898 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JOCLAFEN_02899 1.3e-93 ypuI S Protein of unknown function (DUF3907)
JOCLAFEN_02900 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
JOCLAFEN_02901 2e-103 spmA S Spore maturation protein
JOCLAFEN_02902 3.8e-88 spmB S Spore maturation protein
JOCLAFEN_02903 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JOCLAFEN_02904 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
JOCLAFEN_02905 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
JOCLAFEN_02906 1.2e-192 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
JOCLAFEN_02907 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_02908 0.0 resE 2.7.13.3 T Histidine kinase
JOCLAFEN_02909 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
JOCLAFEN_02910 4.8e-199 rsiX
JOCLAFEN_02911 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOCLAFEN_02912 1.1e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JOCLAFEN_02913 3.6e-41 fer C Ferredoxin
JOCLAFEN_02914 3.3e-197 ypbB 5.1.3.1 S protein conserved in bacteria
JOCLAFEN_02915 4e-270 recQ 3.6.4.12 L DNA helicase
JOCLAFEN_02916 9.9e-100 ypbD S metal-dependent membrane protease
JOCLAFEN_02917 1.2e-76 ypbE M Lysin motif
JOCLAFEN_02918 5.7e-85 ypbF S Protein of unknown function (DUF2663)
JOCLAFEN_02919 4.8e-148 ypbG S Calcineurin-like phosphoesterase superfamily domain
JOCLAFEN_02920 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
JOCLAFEN_02921 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
JOCLAFEN_02922 2e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
JOCLAFEN_02923 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
JOCLAFEN_02924 7e-161 sleB 3.5.1.28 M Spore cortex-lytic enzyme
JOCLAFEN_02925 4.2e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
JOCLAFEN_02926 2.2e-61 ypfA M Flagellar protein YcgR
JOCLAFEN_02927 1.4e-12 S Family of unknown function (DUF5359)
JOCLAFEN_02928 1.2e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JOCLAFEN_02929 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
JOCLAFEN_02930 1e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JOCLAFEN_02931 4.7e-08 S YpzI-like protein
JOCLAFEN_02932 3.2e-104 yphA
JOCLAFEN_02933 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JOCLAFEN_02934 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JOCLAFEN_02935 3.3e-16 yphE S Protein of unknown function (DUF2768)
JOCLAFEN_02936 3.6e-134 yphF
JOCLAFEN_02937 2.2e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
JOCLAFEN_02938 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JOCLAFEN_02939 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
JOCLAFEN_02940 6.6e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
JOCLAFEN_02941 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
JOCLAFEN_02942 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JOCLAFEN_02943 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JOCLAFEN_02944 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
JOCLAFEN_02945 1.7e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
JOCLAFEN_02946 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JOCLAFEN_02947 8.4e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JOCLAFEN_02948 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
JOCLAFEN_02949 1.2e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOCLAFEN_02950 2.4e-160 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JOCLAFEN_02951 1.1e-130 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
JOCLAFEN_02952 5.5e-118 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
JOCLAFEN_02953 4.9e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
JOCLAFEN_02954 3.6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
JOCLAFEN_02955 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JOCLAFEN_02956 1.7e-204 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
JOCLAFEN_02957 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
JOCLAFEN_02958 2e-233 S COG0457 FOG TPR repeat
JOCLAFEN_02959 2.1e-99 ypiB S Belongs to the UPF0302 family
JOCLAFEN_02960 2.5e-77 ypiF S Protein of unknown function (DUF2487)
JOCLAFEN_02961 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
JOCLAFEN_02962 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
JOCLAFEN_02963 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
JOCLAFEN_02964 2.9e-105 ypjA S membrane
JOCLAFEN_02965 4.3e-141 ypjB S sporulation protein
JOCLAFEN_02966 2e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
JOCLAFEN_02967 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
JOCLAFEN_02968 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
JOCLAFEN_02969 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
JOCLAFEN_02970 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
JOCLAFEN_02971 9.6e-132 bshB1 S proteins, LmbE homologs
JOCLAFEN_02972 4.1e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
JOCLAFEN_02973 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JOCLAFEN_02974 1.4e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JOCLAFEN_02975 1.2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
JOCLAFEN_02976 9.4e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JOCLAFEN_02977 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JOCLAFEN_02978 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JOCLAFEN_02979 6.7e-23 ypmA S Protein of unknown function (DUF4264)
JOCLAFEN_02980 4e-81 ypmB S protein conserved in bacteria
JOCLAFEN_02981 9.7e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JOCLAFEN_02982 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
JOCLAFEN_02983 6.8e-130 dnaD L DNA replication protein DnaD
JOCLAFEN_02984 4.9e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JOCLAFEN_02985 8.2e-90 ypoC
JOCLAFEN_02986 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JOCLAFEN_02987 1e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JOCLAFEN_02988 6.3e-187 yppC S Protein of unknown function (DUF2515)
JOCLAFEN_02991 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
JOCLAFEN_02993 9.8e-46 yppG S YppG-like protein
JOCLAFEN_02994 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
JOCLAFEN_02995 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
JOCLAFEN_02996 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
JOCLAFEN_02997 1.1e-236 yprB L RNase_H superfamily
JOCLAFEN_02999 9.9e-33 cotD S Inner spore coat protein D
JOCLAFEN_03000 4.8e-99 ypsA S Belongs to the UPF0398 family
JOCLAFEN_03001 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JOCLAFEN_03002 4.2e-217 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JOCLAFEN_03003 6.6e-22 S YpzG-like protein
JOCLAFEN_03005 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
JOCLAFEN_03006 5.4e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JOCLAFEN_03007 1.3e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JOCLAFEN_03008 2.9e-235 pbuX F xanthine
JOCLAFEN_03010 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
JOCLAFEN_03011 1.4e-32 ydfR S Protein of unknown function (DUF421)
JOCLAFEN_03013 5.8e-49 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
JOCLAFEN_03014 1.5e-109 J Acetyltransferase (GNAT) domain
JOCLAFEN_03015 2.5e-203 bcsA Q Naringenin-chalcone synthase
JOCLAFEN_03016 2.5e-89 ypbQ S protein conserved in bacteria
JOCLAFEN_03017 0.0 ypbR S Dynamin family
JOCLAFEN_03018 1.7e-38 ypbS S Protein of unknown function (DUF2533)
JOCLAFEN_03020 1.4e-164 polA 2.7.7.7 L 5'3' exonuclease
JOCLAFEN_03022 6e-67 rnhA 3.1.26.4 L Ribonuclease
JOCLAFEN_03023 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JOCLAFEN_03024 5.3e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
JOCLAFEN_03025 3.7e-27 ypeQ S Zinc-finger
JOCLAFEN_03026 1.2e-36 S Protein of unknown function (DUF2564)
JOCLAFEN_03027 2e-11 degR
JOCLAFEN_03028 1e-30 cspD K Cold-shock protein
JOCLAFEN_03029 1.7e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
JOCLAFEN_03030 1.1e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JOCLAFEN_03031 1.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JOCLAFEN_03032 4.9e-100 ypgQ S phosphohydrolase
JOCLAFEN_03033 4.7e-157 ypgR C COG0694 Thioredoxin-like proteins and domains
JOCLAFEN_03034 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
JOCLAFEN_03035 1e-75 yphP S Belongs to the UPF0403 family
JOCLAFEN_03036 5.2e-131 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
JOCLAFEN_03037 5.9e-114 ypjP S YpjP-like protein
JOCLAFEN_03038 5.6e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JOCLAFEN_03039 4.8e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOCLAFEN_03040 3.2e-115 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
JOCLAFEN_03041 9.3e-110 hlyIII S protein, Hemolysin III
JOCLAFEN_03042 8.6e-179 pspF K Transcriptional regulator
JOCLAFEN_03043 4.8e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JOCLAFEN_03044 2.6e-39 ypmP S Protein of unknown function (DUF2535)
JOCLAFEN_03045 6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
JOCLAFEN_03046 4.4e-135 ypmR E GDSL-like Lipase/Acylhydrolase
JOCLAFEN_03047 2.1e-97 ypmS S protein conserved in bacteria
JOCLAFEN_03048 4.7e-67 ypoP K transcriptional
JOCLAFEN_03049 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOCLAFEN_03050 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JOCLAFEN_03051 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
JOCLAFEN_03052 1.9e-308 yokA L Recombinase
JOCLAFEN_03056 7e-77 yokF 3.1.31.1 L RNA catabolic process
JOCLAFEN_03057 3.6e-83 G SMI1-KNR4 cell-wall
JOCLAFEN_03060 2.9e-252 iolT EGP Major facilitator Superfamily
JOCLAFEN_03061 1.4e-184 yhfP 1.1.1.1 C Quinone oxidoreductase
JOCLAFEN_03062 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
JOCLAFEN_03063 3.2e-166 ydhU P Catalase
JOCLAFEN_03064 9.3e-297 yveA E amino acid
JOCLAFEN_03065 5.3e-104 yvdT K Transcriptional regulator
JOCLAFEN_03066 2.3e-51 ykkC P Small Multidrug Resistance protein
JOCLAFEN_03067 2.6e-49 sugE P Small Multidrug Resistance protein
JOCLAFEN_03068 1.7e-216 yeaN P COG2807 Cyanate permease
JOCLAFEN_03069 2.6e-118 K FCD
JOCLAFEN_03070 5.1e-133 ydhQ K UTRA
JOCLAFEN_03071 1.2e-195 pbuE EGP Major facilitator Superfamily
JOCLAFEN_03072 1.2e-97 ydhK M Protein of unknown function (DUF1541)
JOCLAFEN_03074 4.3e-266 pbpE V Beta-lactamase
JOCLAFEN_03077 3.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
JOCLAFEN_03078 1.6e-120 ydhC K FCD
JOCLAFEN_03079 4e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
JOCLAFEN_03080 4.4e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
JOCLAFEN_03081 2.7e-114 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
JOCLAFEN_03082 5.3e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
JOCLAFEN_03083 5.3e-150 bltR K helix_turn_helix, mercury resistance
JOCLAFEN_03084 2.9e-81 bltD 2.3.1.57 K FR47-like protein
JOCLAFEN_03085 1.3e-123 ydhB S membrane transporter protein
JOCLAFEN_03086 5e-156 K Helix-turn-helix XRE-family like proteins
JOCLAFEN_03087 3.4e-225 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JOCLAFEN_03088 2.3e-210 tcaB EGP Major facilitator Superfamily
JOCLAFEN_03089 1.1e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
JOCLAFEN_03090 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
JOCLAFEN_03091 1.4e-100 ynaD J Acetyltransferase (GNAT) domain
JOCLAFEN_03092 5.2e-298 expZ S ABC transporter
JOCLAFEN_03093 2.7e-133 puuD S Peptidase C26
JOCLAFEN_03094 4.5e-36 yraG
JOCLAFEN_03095 2.2e-63 yraF M Spore coat protein
JOCLAFEN_03096 5.5e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
JOCLAFEN_03097 1.8e-24 yraE
JOCLAFEN_03098 3.6e-48 yraD M Spore coat protein
JOCLAFEN_03099 8.1e-268 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOCLAFEN_03100 3.7e-157 ydeK EG -transporter
JOCLAFEN_03101 1.7e-102 ydeS K Transcriptional regulator
JOCLAFEN_03102 4.2e-180 ydeR EGP Major facilitator Superfamily
JOCLAFEN_03104 3.5e-114 paiB K Transcriptional regulator
JOCLAFEN_03105 7e-264 K helix_turn_helix gluconate operon transcriptional repressor
JOCLAFEN_03106 6.2e-222 mleN_2 C antiporter
JOCLAFEN_03107 3.6e-67 yraB K helix_turn_helix, mercury resistance
JOCLAFEN_03108 2.6e-202 adhA 1.1.1.1 C alcohol dehydrogenase
JOCLAFEN_03109 8.1e-166 S Sodium Bile acid symporter family
JOCLAFEN_03110 1.4e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
JOCLAFEN_03111 1.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOCLAFEN_03112 1.2e-148 Q ubiE/COQ5 methyltransferase family
JOCLAFEN_03113 1.3e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JOCLAFEN_03114 1.4e-83 F nucleoside 2-deoxyribosyltransferase
JOCLAFEN_03115 1.6e-56 ydeH
JOCLAFEN_03116 7.1e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
JOCLAFEN_03118 4.6e-148 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
JOCLAFEN_03120 1.1e-200 trkA P Oxidoreductase
JOCLAFEN_03121 9.3e-167 czcD P COG1230 Co Zn Cd efflux system component
JOCLAFEN_03122 1.7e-267 ygaK C COG0277 FAD FMN-containing dehydrogenases
JOCLAFEN_03125 4.1e-62 G Cupin domain
JOCLAFEN_03126 1.1e-83 S DinB superfamily
JOCLAFEN_03127 1.1e-181 S Patatin-like phospholipase
JOCLAFEN_03128 2.2e-51 K Transcriptional regulator PadR-like family
JOCLAFEN_03129 4.5e-100 S Protein of unknown function (DUF2812)
JOCLAFEN_03130 3.6e-120 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JOCLAFEN_03131 1.8e-78 carD K Transcription factor
JOCLAFEN_03132 1.4e-30 cspL K Cold shock
JOCLAFEN_03133 7.2e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
JOCLAFEN_03134 2.9e-174 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
JOCLAFEN_03135 2.6e-111 C Enoyl-(Acyl carrier protein) reductase
JOCLAFEN_03136 1.1e-88 K Bacterial regulatory proteins, tetR family
JOCLAFEN_03138 1.1e-110 ywnB S NAD(P)H-binding
JOCLAFEN_03139 3.1e-72 ywnA K Transcriptional regulator
JOCLAFEN_03140 4.5e-63 yyaQ S YjbR
JOCLAFEN_03141 3.3e-71 maoC I N-terminal half of MaoC dehydratase
JOCLAFEN_03142 3.9e-33 S Domain of unknown function with cystatin-like fold (DUF4467)
JOCLAFEN_03143 3.9e-29 S Domain of unknown function with cystatin-like fold (DUF4467)
JOCLAFEN_03144 1.3e-48 ohrR K Transcriptional regulator
JOCLAFEN_03145 2.1e-231 proP EGP Transporter
JOCLAFEN_03146 2.8e-96 ywrO 1.6.5.2 S Flavodoxin-like fold
JOCLAFEN_03147 1.8e-97 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JOCLAFEN_03148 3.3e-78 K Transcriptional regulator
JOCLAFEN_03149 2.7e-29 S Doxx family
JOCLAFEN_03150 1.1e-08
JOCLAFEN_03158 7.3e-58 ydcK S Belongs to the SprT family
JOCLAFEN_03159 1.7e-14
JOCLAFEN_03160 0.0 yhgF K COG2183 Transcriptional accessory protein
JOCLAFEN_03161 2.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
JOCLAFEN_03162 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JOCLAFEN_03163 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
JOCLAFEN_03164 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
JOCLAFEN_03165 1.7e-187 rsbU 3.1.3.3 KT phosphatase
JOCLAFEN_03166 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
JOCLAFEN_03167 1.8e-57 rsbS T antagonist
JOCLAFEN_03168 6.1e-146 rsbR T Positive regulator of sigma-B
JOCLAFEN_03169 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
JOCLAFEN_03170 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
JOCLAFEN_03171 2e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOCLAFEN_03172 2.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
JOCLAFEN_03173 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JOCLAFEN_03174 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
JOCLAFEN_03175 7.5e-264 ydbT S Membrane
JOCLAFEN_03176 2.1e-82 ydbS S Bacterial PH domain
JOCLAFEN_03177 1.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JOCLAFEN_03178 7e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JOCLAFEN_03179 3.5e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JOCLAFEN_03180 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JOCLAFEN_03181 1.4e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOCLAFEN_03182 5.8e-09 S Fur-regulated basic protein A
JOCLAFEN_03183 1.5e-10 S Fur-regulated basic protein B
JOCLAFEN_03184 2.9e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
JOCLAFEN_03185 2.1e-52 ydbL
JOCLAFEN_03186 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JOCLAFEN_03187 3e-170 ydbJ V ABC transporter, ATP-binding protein
JOCLAFEN_03188 3.2e-160 ydbI S AI-2E family transporter
JOCLAFEN_03189 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOCLAFEN_03190 6.7e-119 dctR T COG4565 Response regulator of citrate malate metabolism
JOCLAFEN_03191 5.5e-300 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOCLAFEN_03192 2.5e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
JOCLAFEN_03193 6.5e-156 ydbD P Catalase
JOCLAFEN_03194 1.2e-61 ydbC S Domain of unknown function (DUF4937
JOCLAFEN_03195 1.7e-57 ydbB G Cupin domain
JOCLAFEN_03197 2.6e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
JOCLAFEN_03198 4.1e-54 yvaE P Small Multidrug Resistance protein
JOCLAFEN_03199 2.1e-70 yvaD S Family of unknown function (DUF5360)
JOCLAFEN_03200 6.5e-34 ydaT
JOCLAFEN_03202 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
JOCLAFEN_03203 4.7e-39
JOCLAFEN_03204 5.6e-98
JOCLAFEN_03205 2.5e-79
JOCLAFEN_03207 2.7e-11
JOCLAFEN_03209 1.7e-207 S Histidine kinase
JOCLAFEN_03210 1.3e-69
JOCLAFEN_03211 1.1e-60 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
JOCLAFEN_03212 3.6e-37 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JOCLAFEN_03213 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JOCLAFEN_03214 8e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
JOCLAFEN_03215 0.0 ydaO E amino acid
JOCLAFEN_03216 0.0 ydaN S Bacterial cellulose synthase subunit
JOCLAFEN_03217 2.5e-231 ydaM M Glycosyl transferase family group 2
JOCLAFEN_03218 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
JOCLAFEN_03219 1.8e-148 ydaK T Diguanylate cyclase, GGDEF domain
JOCLAFEN_03220 2.1e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
JOCLAFEN_03221 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOCLAFEN_03222 1.5e-74 lrpC K Transcriptional regulator
JOCLAFEN_03223 1.3e-47 ydzA EGP Major facilitator Superfamily
JOCLAFEN_03224 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
JOCLAFEN_03225 6.8e-77 ydaG 1.4.3.5 S general stress protein
JOCLAFEN_03226 2.5e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
JOCLAFEN_03227 2.7e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
JOCLAFEN_03228 1.8e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_03229 1.3e-287 ydaB IQ acyl-CoA ligase
JOCLAFEN_03230 0.0 mtlR K transcriptional regulator, MtlR
JOCLAFEN_03231 7.5e-174 ydhF S Oxidoreductase
JOCLAFEN_03232 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
JOCLAFEN_03233 3.3e-55 yczJ S biosynthesis
JOCLAFEN_03235 2.1e-117 ycsK E anatomical structure formation involved in morphogenesis
JOCLAFEN_03236 4e-131 kipR K Transcriptional regulator
JOCLAFEN_03237 2.5e-189 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
JOCLAFEN_03238 1e-136 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
JOCLAFEN_03239 2.1e-151 ycsI S Belongs to the D-glutamate cyclase family
JOCLAFEN_03240 4.7e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
JOCLAFEN_03241 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
JOCLAFEN_03242 2.1e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JOCLAFEN_03244 1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
JOCLAFEN_03245 3.1e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
JOCLAFEN_03246 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
JOCLAFEN_03247 7.9e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
JOCLAFEN_03248 1.6e-55
JOCLAFEN_03249 1.2e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
JOCLAFEN_03250 6.1e-299 ycnJ P protein, homolog of Cu resistance protein CopC
JOCLAFEN_03251 5.1e-97 ycnI S protein conserved in bacteria
JOCLAFEN_03252 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_03253 3.6e-149 glcU U Glucose uptake
JOCLAFEN_03254 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOCLAFEN_03255 1e-219 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JOCLAFEN_03256 1.7e-260 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
JOCLAFEN_03257 1.1e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
JOCLAFEN_03258 1e-44 ycnE S Monooxygenase
JOCLAFEN_03259 8.8e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
JOCLAFEN_03260 6e-152 ycnC K Transcriptional regulator
JOCLAFEN_03261 1e-249 ycnB EGP Major facilitator Superfamily
JOCLAFEN_03262 9.3e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
JOCLAFEN_03263 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
JOCLAFEN_03264 1.1e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_03265 6.8e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOCLAFEN_03266 1.9e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
JOCLAFEN_03268 1.9e-81 S aspartate phosphatase
JOCLAFEN_03269 2e-261 T PhoQ Sensor
JOCLAFEN_03270 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
JOCLAFEN_03271 1.3e-225 yclI V ABC transporter (permease) YclI
JOCLAFEN_03272 1.5e-121 yclH P ABC transporter
JOCLAFEN_03273 4.9e-254 yxeQ S MmgE/PrpD family
JOCLAFEN_03274 9.8e-219 yxeP 3.5.1.47 E hydrolase activity
JOCLAFEN_03275 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
JOCLAFEN_03276 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
JOCLAFEN_03277 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
JOCLAFEN_03278 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOCLAFEN_03279 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JOCLAFEN_03280 5.6e-195 gerKB F Spore germination protein
JOCLAFEN_03281 1.2e-235 gerKC S spore germination
JOCLAFEN_03282 9.2e-295 gerKA EG Spore germination protein
JOCLAFEN_03284 7.5e-279 yclG M Pectate lyase superfamily protein
JOCLAFEN_03285 4.1e-270 dtpT E amino acid peptide transporter
JOCLAFEN_03287 9.3e-29 Q PFAM Collagen triple helix
JOCLAFEN_03288 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
JOCLAFEN_03289 5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
JOCLAFEN_03290 1.3e-57 yflT S Heat induced stress protein YflT
JOCLAFEN_03291 7.7e-24 S Protein of unknown function (DUF3212)
JOCLAFEN_03292 1.2e-188 yfmJ S N-terminal domain of oxidoreductase
JOCLAFEN_03293 4.6e-63 yfmK 2.3.1.128 K acetyltransferase
JOCLAFEN_03294 4.2e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
JOCLAFEN_03295 1.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOCLAFEN_03296 1.4e-207 yfmO EGP Major facilitator Superfamily
JOCLAFEN_03297 1.8e-69 yfmP K transcriptional
JOCLAFEN_03298 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
JOCLAFEN_03299 1.6e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOCLAFEN_03300 6.5e-145 IQ Enoyl-(Acyl carrier protein) reductase
JOCLAFEN_03301 9.8e-115 yfmS NT chemotaxis protein
JOCLAFEN_03302 5.9e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
JOCLAFEN_03303 7.8e-247 yfnA E amino acid
JOCLAFEN_03304 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
JOCLAFEN_03305 5.6e-188 yfnD M Nucleotide-diphospho-sugar transferase
JOCLAFEN_03306 2.5e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
JOCLAFEN_03307 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
JOCLAFEN_03308 1.2e-171 yfnG 4.2.1.45 M dehydratase
JOCLAFEN_03309 2.3e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
JOCLAFEN_03310 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOCLAFEN_03312 1.1e-144 2.1.1.163, 2.1.1.201 Q methyltransferase
JOCLAFEN_03313 2.3e-111 S CAAX protease self-immunity
JOCLAFEN_03314 8.6e-153 sagB C Nitroreductase family
JOCLAFEN_03315 1.2e-266 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
JOCLAFEN_03316 9.7e-191 S ATP diphosphatase activity
JOCLAFEN_03317 6.4e-128
JOCLAFEN_03318 3.2e-74 S protein homooligomerization
JOCLAFEN_03319 2.4e-125 V ABC-2 type transporter
JOCLAFEN_03320 2.8e-165 V ATPases associated with a variety of cellular activities
JOCLAFEN_03321 3.1e-50 MA20_23570 K Winged helix DNA-binding domain
JOCLAFEN_03323 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
JOCLAFEN_03324 9.8e-197 yetN S Protein of unknown function (DUF3900)
JOCLAFEN_03325 1.4e-206 yetM CH FAD binding domain
JOCLAFEN_03326 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
JOCLAFEN_03328 8.2e-106 yetJ S Belongs to the BI1 family
JOCLAFEN_03329 9e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
JOCLAFEN_03330 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
JOCLAFEN_03331 3.4e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
JOCLAFEN_03332 9.8e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOCLAFEN_03333 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
JOCLAFEN_03334 5.7e-121 yetF S membrane
JOCLAFEN_03336 1.2e-97 yesJ K Acetyltransferase (GNAT) family
JOCLAFEN_03337 8.9e-104 cotJC P Spore Coat
JOCLAFEN_03338 3.3e-45 cotJB S CotJB protein
JOCLAFEN_03339 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
JOCLAFEN_03340 2.4e-108 aadK G Streptomycin adenylyltransferase
JOCLAFEN_03342 9.4e-127 yeeN K transcriptional regulatory protein
JOCLAFEN_03343 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
JOCLAFEN_03344 1.1e-57 S Protein of unknown function, DUF600
JOCLAFEN_03345 8.2e-76 S Protein of unknown function, DUF600
JOCLAFEN_03346 1.5e-41 S Immunity protein 22
JOCLAFEN_03347 0.0 K SIR2-like domain
JOCLAFEN_03348 2e-14 L Recombinase zinc beta ribbon domain
JOCLAFEN_03349 6.4e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOCLAFEN_03350 2.1e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
JOCLAFEN_03351 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JOCLAFEN_03352 1.7e-151 yerO K Transcriptional regulator
JOCLAFEN_03353 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOCLAFEN_03354 1.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JOCLAFEN_03355 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOCLAFEN_03356 1.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JOCLAFEN_03357 1.3e-120 sapB S MgtC SapB transporter
JOCLAFEN_03358 5e-195 yerI S homoserine kinase type II (protein kinase fold)
JOCLAFEN_03359 1.4e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
JOCLAFEN_03360 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JOCLAFEN_03361 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JOCLAFEN_03362 6.9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
JOCLAFEN_03363 3.3e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
JOCLAFEN_03364 2.4e-50 yerC S protein conserved in bacteria
JOCLAFEN_03365 1.2e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
JOCLAFEN_03366 0.0 yerA 3.5.4.2 F adenine deaminase
JOCLAFEN_03367 2e-25 S Protein of unknown function (DUF2892)
JOCLAFEN_03368 3.7e-235 purD 6.3.4.13 F Belongs to the GARS family
JOCLAFEN_03369 5e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
JOCLAFEN_03370 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JOCLAFEN_03371 4.6e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
JOCLAFEN_03372 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JOCLAFEN_03373 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOCLAFEN_03374 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOCLAFEN_03375 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JOCLAFEN_03376 6.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
JOCLAFEN_03377 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JOCLAFEN_03378 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JOCLAFEN_03379 3.7e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JOCLAFEN_03380 5.5e-29 yebG S NETI protein
JOCLAFEN_03381 3.4e-92 yebE S UPF0316 protein
JOCLAFEN_03383 1.1e-125 yebC M Membrane
JOCLAFEN_03384 8.1e-209 pbuG S permease
JOCLAFEN_03385 2.7e-250 S Domain of unknown function (DUF4179)
JOCLAFEN_03386 7.8e-94 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JOCLAFEN_03387 1.5e-127 K Acetyltransferase (GNAT) domain
JOCLAFEN_03388 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JOCLAFEN_03389 0.0 yebA E COG1305 Transglutaminase-like enzymes
JOCLAFEN_03390 3e-215 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
JOCLAFEN_03391 4.6e-177 yeaC S COG0714 MoxR-like ATPases
JOCLAFEN_03392 2.9e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOCLAFEN_03393 1.6e-244 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
JOCLAFEN_03394 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
JOCLAFEN_03395 7.2e-35 ydjO S Cold-inducible protein YdjO
JOCLAFEN_03397 2.7e-135 ydjN U Involved in the tonB-independent uptake of proteins
JOCLAFEN_03398 4.2e-62 ydjM M Lytic transglycolase
JOCLAFEN_03399 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
JOCLAFEN_03400 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
JOCLAFEN_03401 2.3e-143 rsiV S Protein of unknown function (DUF3298)
JOCLAFEN_03402 0.0 yrhL I Acyltransferase family
JOCLAFEN_03403 1.2e-143 ydjI S virion core protein (lumpy skin disease virus)
JOCLAFEN_03404 1.8e-120 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
JOCLAFEN_03405 1.8e-179 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOCLAFEN_03406 6.7e-114 pspA KT Phage shock protein A
JOCLAFEN_03407 2.8e-30 yjdJ S Domain of unknown function (DUF4306)
JOCLAFEN_03408 2.7e-169 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
JOCLAFEN_03409 9.8e-250 gutA G MFS/sugar transport protein
JOCLAFEN_03410 1.9e-200 gutB 1.1.1.14 E Dehydrogenase
JOCLAFEN_03411 0.0 K NB-ARC domain
JOCLAFEN_03412 0.0 res 2.1.1.72, 3.1.21.5 V Type III restriction enzyme, res subunit
JOCLAFEN_03413 1.5e-240 mod 2.1.1.72 L DNA methylase
JOCLAFEN_03414 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JOCLAFEN_03415 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JOCLAFEN_03416 3.3e-127 ydiL S CAAX protease self-immunity
JOCLAFEN_03417 1.7e-27 ydiK S Domain of unknown function (DUF4305)
JOCLAFEN_03418 1e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JOCLAFEN_03419 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
JOCLAFEN_03420 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JOCLAFEN_03421 1e-87 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
JOCLAFEN_03422 0.0 ydiF S ABC transporter
JOCLAFEN_03423 3e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JOCLAFEN_03424 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
JOCLAFEN_03425 8.4e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
JOCLAFEN_03426 1.2e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
JOCLAFEN_03427 3.9e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JOCLAFEN_03429 3.7e-165 ygxA S Nucleotidyltransferase-like
JOCLAFEN_03430 1.5e-56 ygzB S UPF0295 protein
JOCLAFEN_03431 1.8e-80 perR P Belongs to the Fur family
JOCLAFEN_03432 1.5e-85 bcp 1.11.1.15 O Peroxiredoxin
JOCLAFEN_03433 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
JOCLAFEN_03434 1.7e-177 ygaE S Membrane
JOCLAFEN_03435 4.2e-306 ygaD V ABC transporter
JOCLAFEN_03436 2.2e-104 ygaC J Belongs to the UPF0374 family
JOCLAFEN_03437 1.5e-37 ygaB S YgaB-like protein
JOCLAFEN_03439 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOCLAFEN_03440 8.2e-37 yfhS
JOCLAFEN_03441 2.7e-210 mutY L A G-specific
JOCLAFEN_03442 1e-184 yfhP S membrane-bound metal-dependent
JOCLAFEN_03443 0.0 yfhO S Bacterial membrane protein YfhO
JOCLAFEN_03444 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
JOCLAFEN_03445 3.7e-170 yfhM S Alpha/beta hydrolase family
JOCLAFEN_03446 2.6e-34 yfhL S SdpI/YhfL protein family
JOCLAFEN_03447 1.7e-93 batE T Bacterial SH3 domain homologues
JOCLAFEN_03448 2.2e-44 yfhJ S WVELL protein
JOCLAFEN_03449 3.4e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
JOCLAFEN_03451 2.6e-206 yfhI EGP Major facilitator Superfamily
JOCLAFEN_03452 8.8e-53 yfhH S Protein of unknown function (DUF1811)
JOCLAFEN_03453 5.1e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
JOCLAFEN_03454 3.1e-167 yfhF S nucleoside-diphosphate sugar epimerase
JOCLAFEN_03456 2.1e-25 yfhD S YfhD-like protein
JOCLAFEN_03457 3.3e-106 yfhC C nitroreductase
JOCLAFEN_03458 8.7e-167 yfhB 5.3.3.17 S PhzF family
JOCLAFEN_03459 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOCLAFEN_03460 5.6e-83 yfiV K transcriptional
JOCLAFEN_03461 1.2e-288 yfiU EGP Major facilitator Superfamily
JOCLAFEN_03462 1.3e-99 yfiT S Belongs to the metal hydrolase YfiT family
JOCLAFEN_03463 4.5e-45 yrdF K ribonuclease inhibitor
JOCLAFEN_03464 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
JOCLAFEN_03465 3.1e-182 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
JOCLAFEN_03466 2.7e-111 1.6.5.2 S NADPH-dependent FMN reductase
JOCLAFEN_03467 1.7e-96 padR K transcriptional
JOCLAFEN_03468 1.2e-169 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
JOCLAFEN_03469 2e-160 yfiE 1.13.11.2 S glyoxalase
JOCLAFEN_03470 4.1e-63 mhqP S DoxX
JOCLAFEN_03471 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
JOCLAFEN_03472 0.0 yfiB3 V ABC transporter
JOCLAFEN_03473 9.2e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOCLAFEN_03474 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
JOCLAFEN_03475 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
JOCLAFEN_03476 4.2e-15 sspH S Belongs to the SspH family
JOCLAFEN_03477 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
JOCLAFEN_03478 1.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
JOCLAFEN_03479 5.2e-215 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOCLAFEN_03480 6.1e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
JOCLAFEN_03481 2.9e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
JOCLAFEN_03482 8.7e-89 yfjM S Psort location Cytoplasmic, score
JOCLAFEN_03483 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOCLAFEN_03484 2.3e-50 S YfzA-like protein
JOCLAFEN_03485 5.6e-269 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOCLAFEN_03486 5.7e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JOCLAFEN_03487 3.8e-184 corA P Mediates influx of magnesium ions
JOCLAFEN_03488 7.9e-32
JOCLAFEN_03489 2.5e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
JOCLAFEN_03490 4.5e-154 pdaA G deacetylase
JOCLAFEN_03491 4.9e-27 yfjT
JOCLAFEN_03492 1.5e-219 yfkA S YfkB-like domain
JOCLAFEN_03493 5.6e-147 yfkC M Mechanosensitive ion channel
JOCLAFEN_03494 2.5e-144 yfkD S YfkD-like protein
JOCLAFEN_03495 1.3e-185 cax P COG0387 Ca2 H antiporter
JOCLAFEN_03496 5e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
JOCLAFEN_03497 2.5e-07
JOCLAFEN_03498 8.9e-145 yihY S Belongs to the UPF0761 family
JOCLAFEN_03499 8.5e-51 yfkI S gas vesicle protein
JOCLAFEN_03500 3.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOCLAFEN_03501 2.7e-29 yfkK S Belongs to the UPF0435 family
JOCLAFEN_03502 1.5e-193 ydiM EGP Major facilitator Superfamily
JOCLAFEN_03503 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
JOCLAFEN_03504 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JOCLAFEN_03505 1.5e-186 K helix_turn _helix lactose operon repressor
JOCLAFEN_03506 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
JOCLAFEN_03507 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
JOCLAFEN_03508 1.6e-200 yibE S YibE/F-like protein
JOCLAFEN_03509 4.2e-125 yibF S YibE/F-like protein
JOCLAFEN_03510 1.2e-123 yfkO C nitroreductase
JOCLAFEN_03511 2.6e-129 treR K transcriptional
JOCLAFEN_03512 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
JOCLAFEN_03513 9.5e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
JOCLAFEN_03514 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
JOCLAFEN_03515 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
JOCLAFEN_03516 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
JOCLAFEN_03517 2.3e-63 yhdN S Domain of unknown function (DUF1992)
JOCLAFEN_03518 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
JOCLAFEN_03519 5.3e-72 yfmQ S Uncharacterised protein from bacillus cereus group
JOCLAFEN_03520 2.5e-245 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
JOCLAFEN_03521 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
JOCLAFEN_03522 3.1e-50 yflH S Protein of unknown function (DUF3243)
JOCLAFEN_03523 7e-19 yflI
JOCLAFEN_03524 1.5e-14 yflJ S Protein of unknown function (DUF2639)
JOCLAFEN_03525 4.4e-123 yflK S protein conserved in bacteria
JOCLAFEN_03526 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JOCLAFEN_03527 4.2e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
JOCLAFEN_03528 3.9e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
JOCLAFEN_03529 3.8e-227 citM C Citrate transporter
JOCLAFEN_03530 1.8e-178 yflP S Tripartite tricarboxylate transporter family receptor
JOCLAFEN_03531 4.4e-118 citT T response regulator
JOCLAFEN_03532 6.7e-274 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
JOCLAFEN_03533 3.5e-80 srtA 3.4.22.70 M Sortase family
JOCLAFEN_03534 0.0 M1-568 M cell wall anchor domain
JOCLAFEN_03535 2.5e-152 M1-574 T Transcriptional regulatory protein, C terminal
JOCLAFEN_03536 0.0 ywpD T PhoQ Sensor
JOCLAFEN_03537 6.8e-24 M1-820 Q Collagen triple helix repeat (20 copies)
JOCLAFEN_03538 3.3e-23 M1-820 Q Collagen triple helix repeat (20 copies)
JOCLAFEN_03541 7.5e-77 ctsR K Belongs to the CtsR family
JOCLAFEN_03542 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
JOCLAFEN_03543 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
JOCLAFEN_03544 0.0 clpC O Belongs to the ClpA ClpB family
JOCLAFEN_03545 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JOCLAFEN_03546 6.4e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
JOCLAFEN_03547 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
JOCLAFEN_03548 2.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
JOCLAFEN_03549 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
JOCLAFEN_03550 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JOCLAFEN_03551 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
JOCLAFEN_03552 2.4e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOCLAFEN_03553 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JOCLAFEN_03554 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOCLAFEN_03555 4.2e-89 yacP S RNA-binding protein containing a PIN domain
JOCLAFEN_03556 8.9e-116 sigH K Belongs to the sigma-70 factor family
JOCLAFEN_03557 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JOCLAFEN_03558 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
JOCLAFEN_03559 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JOCLAFEN_03560 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JOCLAFEN_03561 3e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JOCLAFEN_03562 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JOCLAFEN_03563 9.7e-109 rsmC 2.1.1.172 J Methyltransferase
JOCLAFEN_03564 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOCLAFEN_03565 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOCLAFEN_03566 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
JOCLAFEN_03567 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JOCLAFEN_03568 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JOCLAFEN_03569 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JOCLAFEN_03570 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JOCLAFEN_03571 1.5e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
JOCLAFEN_03572 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
JOCLAFEN_03573 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JOCLAFEN_03574 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
JOCLAFEN_03575 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JOCLAFEN_03576 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JOCLAFEN_03577 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JOCLAFEN_03578 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JOCLAFEN_03579 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JOCLAFEN_03580 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JOCLAFEN_03581 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
JOCLAFEN_03582 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JOCLAFEN_03583 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JOCLAFEN_03584 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JOCLAFEN_03585 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JOCLAFEN_03586 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOCLAFEN_03587 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JOCLAFEN_03588 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JOCLAFEN_03589 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JOCLAFEN_03590 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JOCLAFEN_03591 1.9e-23 rpmD J Ribosomal protein L30
JOCLAFEN_03592 1.1e-72 rplO J binds to the 23S rRNA
JOCLAFEN_03593 1.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JOCLAFEN_03594 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JOCLAFEN_03595 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
JOCLAFEN_03596 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JOCLAFEN_03597 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
JOCLAFEN_03598 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JOCLAFEN_03599 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JOCLAFEN_03600 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOCLAFEN_03601 4.7e-58 rplQ J Ribosomal protein L17
JOCLAFEN_03602 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOCLAFEN_03603 7.3e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOCLAFEN_03604 1.1e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOCLAFEN_03605 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JOCLAFEN_03606 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JOCLAFEN_03607 3.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
JOCLAFEN_03608 3.1e-144 ybaJ Q Methyltransferase domain
JOCLAFEN_03609 3.6e-82 yizA S Damage-inducible protein DinB
JOCLAFEN_03610 6.5e-78 ybaK S Protein of unknown function (DUF2521)
JOCLAFEN_03611 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
JOCLAFEN_03612 6.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
JOCLAFEN_03613 7.6e-76 gerD
JOCLAFEN_03614 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
JOCLAFEN_03615 8.4e-134 pdaB 3.5.1.104 G Polysaccharide deacetylase
JOCLAFEN_03616 1.1e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JOCLAFEN_03617 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOCLAFEN_03618 4.5e-29 yazB K transcriptional
JOCLAFEN_03619 1.9e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JOCLAFEN_03620 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JOCLAFEN_03621 3.6e-157 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JOCLAFEN_03622 1.9e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
JOCLAFEN_03623 2.3e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
JOCLAFEN_03624 3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JOCLAFEN_03625 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
JOCLAFEN_03626 9.1e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
JOCLAFEN_03627 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JOCLAFEN_03628 1.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JOCLAFEN_03629 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JOCLAFEN_03630 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JOCLAFEN_03631 2.2e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JOCLAFEN_03632 3.1e-184 KLT serine threonine protein kinase
JOCLAFEN_03633 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
JOCLAFEN_03634 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
JOCLAFEN_03637 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
JOCLAFEN_03638 4.1e-57 divIC D Septum formation initiator
JOCLAFEN_03639 5.8e-104 yabQ S spore cortex biosynthesis protein
JOCLAFEN_03640 1.9e-49 yabP S Sporulation protein YabP
JOCLAFEN_03641 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
JOCLAFEN_03642 7.7e-277 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
JOCLAFEN_03643 1.2e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
JOCLAFEN_03644 6.2e-91 spoVT K stage V sporulation protein
JOCLAFEN_03645 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JOCLAFEN_03646 3.7e-40 yabK S Peptide ABC transporter permease
JOCLAFEN_03647 4.2e-106 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JOCLAFEN_03648 1.7e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JOCLAFEN_03649 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOCLAFEN_03650 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JOCLAFEN_03651 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
JOCLAFEN_03652 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
JOCLAFEN_03653 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JOCLAFEN_03654 4.6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JOCLAFEN_03655 2.9e-27 sspF S DNA topological change
JOCLAFEN_03656 7.8e-39 veg S protein conserved in bacteria
JOCLAFEN_03657 8.4e-146 yabG S peptidase
JOCLAFEN_03658 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JOCLAFEN_03659 2.3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JOCLAFEN_03660 5.4e-232 rpfB GH23 T protein conserved in bacteria
JOCLAFEN_03661 1.5e-143 tatD L hydrolase, TatD
JOCLAFEN_03662 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOCLAFEN_03663 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
JOCLAFEN_03664 6.9e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JOCLAFEN_03665 1.4e-47 yazA L endonuclease containing a URI domain
JOCLAFEN_03666 3.2e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
JOCLAFEN_03667 7.7e-37 yabA L Involved in initiation control of chromosome replication
JOCLAFEN_03668 8.8e-145 yaaT S stage 0 sporulation protein
JOCLAFEN_03669 1.3e-182 holB 2.7.7.7 L DNA polymerase III
JOCLAFEN_03670 1.2e-71 yaaR S protein conserved in bacteria
JOCLAFEN_03671 7.5e-55 yaaQ S protein conserved in bacteria
JOCLAFEN_03672 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JOCLAFEN_03673 8.9e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
JOCLAFEN_03674 8.4e-191 yaaN P Belongs to the TelA family
JOCLAFEN_03675 1.9e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
JOCLAFEN_03676 2.2e-30 csfB S Inhibitor of sigma-G Gin
JOCLAFEN_03677 1.6e-301 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
JOCLAFEN_03678 4.9e-125 yhcW 5.4.2.6 S hydrolase
JOCLAFEN_03679 7.6e-68 yhcV S COG0517 FOG CBS domain
JOCLAFEN_03680 1.3e-69 yhcU S Family of unknown function (DUF5365)
JOCLAFEN_03681 2.8e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOCLAFEN_03682 3.4e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
JOCLAFEN_03683 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
JOCLAFEN_03684 5.8e-115 yhcQ M Spore coat protein
JOCLAFEN_03685 3.3e-161 yhcP
JOCLAFEN_03686 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
JOCLAFEN_03687 2e-55 yhcM
JOCLAFEN_03688 2.1e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOCLAFEN_03689 2.4e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
JOCLAFEN_03690 1.3e-148 metQ M Belongs to the nlpA lipoprotein family
JOCLAFEN_03691 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
JOCLAFEN_03692 4.4e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
JOCLAFEN_03693 6.9e-167 yhcH V ABC transporter, ATP-binding protein
JOCLAFEN_03694 5.1e-125 yhcG V ABC transporter, ATP-binding protein
JOCLAFEN_03695 7.3e-62 yhcF K Transcriptional regulator
JOCLAFEN_03696 9.6e-53
JOCLAFEN_03697 3.8e-55 yhcC
JOCLAFEN_03698 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
JOCLAFEN_03699 8.4e-285 yhcA EGP Major facilitator Superfamily
JOCLAFEN_03700 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
JOCLAFEN_03701 4.6e-74 yhbI K DNA-binding transcription factor activity
JOCLAFEN_03702 2.7e-216 yhbH S Belongs to the UPF0229 family
JOCLAFEN_03703 0.0 prkA T Ser protein kinase
JOCLAFEN_03705 3.3e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
JOCLAFEN_03706 2.6e-60 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
JOCLAFEN_03707 1e-108 yhbD K Protein of unknown function (DUF4004)
JOCLAFEN_03708 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JOCLAFEN_03709 6.9e-175 yhbB S Putative amidase domain
JOCLAFEN_03710 9.2e-225 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JOCLAFEN_03711 1.6e-111 yhzB S B3/4 domain
JOCLAFEN_03713 6.6e-81 ygaO
JOCLAFEN_03714 7.8e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOCLAFEN_03715 3.8e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
JOCLAFEN_03716 3.4e-144 ssuC P ABC transporter (permease)
JOCLAFEN_03717 2.7e-180 ssuA M Sulfonate ABC transporter
JOCLAFEN_03718 2.3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
JOCLAFEN_03719 8.9e-186 S Amidohydrolase
JOCLAFEN_03720 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
JOCLAFEN_03721 1.1e-133 oppF3 E Belongs to the ABC transporter superfamily
JOCLAFEN_03722 1.2e-135 oppD3 P Belongs to the ABC transporter superfamily
JOCLAFEN_03723 1.5e-126 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOCLAFEN_03724 1.7e-136 appB P Binding-protein-dependent transport system inner membrane component
JOCLAFEN_03725 1.6e-228 oppA5 E PFAM extracellular solute-binding protein family 5
JOCLAFEN_03727 1.2e-266 ygaK C Berberine and berberine like
JOCLAFEN_03728 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JOCLAFEN_03729 1.7e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
JOCLAFEN_03730 7.7e-283 C Na+/H+ antiporter family
JOCLAFEN_03734 1.6e-08
JOCLAFEN_03737 5.5e-130 IQ reductase
JOCLAFEN_03738 4.1e-248 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
JOCLAFEN_03741 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
JOCLAFEN_03742 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
JOCLAFEN_03743 1.9e-161 K LysR substrate binding domain
JOCLAFEN_03744 3.2e-50 S GlpM protein
JOCLAFEN_03745 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
JOCLAFEN_03746 1.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
JOCLAFEN_03747 3.3e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JOCLAFEN_03748 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOCLAFEN_03749 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOCLAFEN_03750 1.5e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOCLAFEN_03751 2.4e-25 yqzJ
JOCLAFEN_03752 3.5e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOCLAFEN_03753 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
JOCLAFEN_03754 9.7e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
JOCLAFEN_03755 2.5e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
JOCLAFEN_03757 3.1e-95 yqjB S protein conserved in bacteria
JOCLAFEN_03758 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
JOCLAFEN_03759 1e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
JOCLAFEN_03760 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
JOCLAFEN_03761 1.5e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
JOCLAFEN_03762 0.0 pksJ Q Polyketide synthase of type I
JOCLAFEN_03763 0.0 1.1.1.320 Q Polyketide synthase of type I
JOCLAFEN_03764 0.0 Q Polyketide synthase of type I
JOCLAFEN_03765 5.7e-183 yaaC S YaaC-like Protein
JOCLAFEN_03766 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
JOCLAFEN_03767 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JOCLAFEN_03768 1.3e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JOCLAFEN_03769 9.5e-109 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JOCLAFEN_03770 1.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JOCLAFEN_03771 2.9e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
JOCLAFEN_03772 1.3e-09
JOCLAFEN_03773 4.1e-121 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
JOCLAFEN_03774 4.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
JOCLAFEN_03775 3.8e-211 yaaH M Glycoside Hydrolase Family
JOCLAFEN_03776 2.2e-99 yaaI Q COG1335 Amidases related to nicotinamidase
JOCLAFEN_03777 7.8e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JOCLAFEN_03778 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOCLAFEN_03779 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JOCLAFEN_03780 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JOCLAFEN_03781 3.6e-32 yaaL S Protein of unknown function (DUF2508)
JOCLAFEN_03782 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
JOCLAFEN_03783 3.4e-39 S COG NOG14552 non supervised orthologous group
JOCLAFEN_03784 3.6e-134 L Molecular Function DNA binding, Biological Process DNA recombination
JOCLAFEN_03787 1.6e-08
JOCLAFEN_03796 2e-08
JOCLAFEN_03799 1.6e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)