ORF_ID e_value Gene_name EC_number CAZy COGs Description
IHFHMFKI_00009 1.3e-76 tspO T membrane
IHFHMFKI_00010 2.4e-130 dksA T COG1734 DnaK suppressor protein
IHFHMFKI_00011 1.2e-271 menF 5.4.4.2 HQ Isochorismate synthase
IHFHMFKI_00012 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IHFHMFKI_00013 2.1e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
IHFHMFKI_00014 4.6e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IHFHMFKI_00015 2e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
IHFHMFKI_00016 1.6e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
IHFHMFKI_00017 2e-23 S Domain of Unknown Function (DUF1540)
IHFHMFKI_00018 2.4e-184 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
IHFHMFKI_00019 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
IHFHMFKI_00020 7.9e-41 rpmE2 J Ribosomal protein L31
IHFHMFKI_00021 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IHFHMFKI_00022 1.2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IHFHMFKI_00023 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IHFHMFKI_00024 5.7e-74 ytkA S YtkA-like
IHFHMFKI_00026 7.8e-76 dps P Belongs to the Dps family
IHFHMFKI_00027 5e-61 ytkC S Bacteriophage holin family
IHFHMFKI_00028 9.8e-88 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
IHFHMFKI_00029 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
IHFHMFKI_00030 3.2e-144 ytlC P ABC transporter
IHFHMFKI_00031 8.9e-184 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
IHFHMFKI_00032 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
IHFHMFKI_00033 1.6e-38 ytmB S Protein of unknown function (DUF2584)
IHFHMFKI_00034 1.2e-307 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IHFHMFKI_00035 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IHFHMFKI_00036 0.0 asnB 6.3.5.4 E Asparagine synthase
IHFHMFKI_00037 6.3e-260 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
IHFHMFKI_00038 3.9e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IHFHMFKI_00039 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
IHFHMFKI_00040 1.6e-210 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
IHFHMFKI_00041 1.5e-141 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
IHFHMFKI_00043 2.8e-105 ytqB J Putative rRNA methylase
IHFHMFKI_00044 1.1e-189 yhcC S Fe-S oxidoreductase
IHFHMFKI_00045 2e-281 norB EGP COG0477 Permeases of the major facilitator superfamily
IHFHMFKI_00046 6.8e-193 K helix_turn_helix, Arsenical Resistance Operon Repressor
IHFHMFKI_00047 7.4e-40 ytzC S Protein of unknown function (DUF2524)
IHFHMFKI_00049 3.9e-66 ytrA K GntR family transcriptional regulator
IHFHMFKI_00050 1.9e-161 ytrB P abc transporter atp-binding protein
IHFHMFKI_00051 1.3e-163 S ABC-2 family transporter protein
IHFHMFKI_00052 6.5e-171 P ABC-2 family transporter protein
IHFHMFKI_00053 4e-152
IHFHMFKI_00054 2.2e-125 ytrE V ABC transporter, ATP-binding protein
IHFHMFKI_00055 1.4e-221 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
IHFHMFKI_00056 1.4e-89 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_00057 3.3e-178 T PhoQ Sensor
IHFHMFKI_00058 4.9e-134 bceA V ABC transporter, ATP-binding protein
IHFHMFKI_00059 0.0 bceB V ABC transporter (permease)
IHFHMFKI_00060 1.4e-122 ywaF S Integral membrane protein
IHFHMFKI_00061 1.8e-207 yttB EGP Major facilitator Superfamily
IHFHMFKI_00062 3.8e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
IHFHMFKI_00063 1.2e-52 ytvB S Protein of unknown function (DUF4257)
IHFHMFKI_00064 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHFHMFKI_00065 5.6e-52 ytwF P Sulfurtransferase
IHFHMFKI_00066 1.7e-84 M Acetyltransferase (GNAT) domain
IHFHMFKI_00067 1e-248 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
IHFHMFKI_00068 5.3e-142 amyC P ABC transporter (permease)
IHFHMFKI_00069 1.6e-168 amyD G Binding-protein-dependent transport system inner membrane component
IHFHMFKI_00070 7.5e-244 msmE G Bacterial extracellular solute-binding protein
IHFHMFKI_00071 6.3e-185 msmR K Transcriptional regulator
IHFHMFKI_00072 9e-26 yteV S Sporulation protein Cse60
IHFHMFKI_00073 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
IHFHMFKI_00074 5.7e-236 ytfP S HI0933-like protein
IHFHMFKI_00075 1.7e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IHFHMFKI_00076 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHFHMFKI_00077 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
IHFHMFKI_00078 6.4e-128 ythP V ABC transporter
IHFHMFKI_00079 4.6e-216 ythQ U Bacterial ABC transporter protein EcsB
IHFHMFKI_00080 1.3e-227 pbuO S permease
IHFHMFKI_00081 3.1e-267 pepV 3.5.1.18 E Dipeptidase
IHFHMFKI_00082 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IHFHMFKI_00083 2.3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
IHFHMFKI_00084 1.2e-166 ytlQ
IHFHMFKI_00085 4e-147 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IHFHMFKI_00086 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
IHFHMFKI_00087 3.5e-45 ytzH S YtzH-like protein
IHFHMFKI_00088 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IHFHMFKI_00089 2.1e-162 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
IHFHMFKI_00090 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
IHFHMFKI_00091 1.7e-51 ytzB S small secreted protein
IHFHMFKI_00092 5.8e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
IHFHMFKI_00093 3.2e-77 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
IHFHMFKI_00094 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IHFHMFKI_00095 1.4e-147 ytpQ S Belongs to the UPF0354 family
IHFHMFKI_00096 2.4e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHFHMFKI_00097 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IHFHMFKI_00098 1.4e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IHFHMFKI_00099 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IHFHMFKI_00100 1.7e-16 ytxH S COG4980 Gas vesicle protein
IHFHMFKI_00101 2.5e-42 ytxJ O Protein of unknown function (DUF2847)
IHFHMFKI_00102 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
IHFHMFKI_00103 6.4e-182 ccpA K catabolite control protein A
IHFHMFKI_00104 6.6e-145 motA N flagellar motor
IHFHMFKI_00105 3.7e-120 motS N Flagellar motor protein
IHFHMFKI_00106 1.1e-228 acuC BQ histone deacetylase
IHFHMFKI_00107 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
IHFHMFKI_00108 6.8e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
IHFHMFKI_00109 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IHFHMFKI_00110 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IHFHMFKI_00111 1.6e-46 azlD S Branched-chain amino acid transport protein (AzlD)
IHFHMFKI_00112 5.2e-125 azlC E AzlC protein
IHFHMFKI_00113 1.4e-147 K Transcriptional regulator
IHFHMFKI_00114 8.1e-149 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHFHMFKI_00115 1.5e-135 E GDSL-like Lipase/Acylhydrolase family
IHFHMFKI_00117 1.7e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
IHFHMFKI_00118 2.5e-09
IHFHMFKI_00119 9.2e-220 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IHFHMFKI_00120 9.9e-100 yokH G SMI1 / KNR4 family
IHFHMFKI_00121 2.3e-254 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IHFHMFKI_00122 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IHFHMFKI_00123 9.5e-282 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
IHFHMFKI_00124 1.6e-85 ytsP 1.8.4.14 T GAF domain-containing protein
IHFHMFKI_00125 3.8e-108 yttP K Transcriptional regulator
IHFHMFKI_00126 3e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
IHFHMFKI_00127 2.1e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IHFHMFKI_00128 3.2e-237 braB E Component of the transport system for branched-chain amino acids
IHFHMFKI_00129 3.8e-207 iscS2 2.8.1.7 E Cysteine desulfurase
IHFHMFKI_00130 4.8e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IHFHMFKI_00131 3.9e-31 sspB S spore protein
IHFHMFKI_00132 4.2e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
IHFHMFKI_00133 0.0 ytcJ S amidohydrolase
IHFHMFKI_00134 8.3e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHFHMFKI_00135 6.4e-182 sppA OU signal peptide peptidase SppA
IHFHMFKI_00136 4.5e-88 yteJ S RDD family
IHFHMFKI_00137 1e-93 ytfI S Protein of unknown function (DUF2953)
IHFHMFKI_00138 1.6e-60 ytfJ S Sporulation protein YtfJ
IHFHMFKI_00139 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IHFHMFKI_00140 9.3e-178 ytxK 2.1.1.72 L DNA methylase
IHFHMFKI_00141 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IHFHMFKI_00142 1e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
IHFHMFKI_00143 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IHFHMFKI_00144 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
IHFHMFKI_00146 6.5e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_00147 1.3e-128 ytkL S Belongs to the UPF0173 family
IHFHMFKI_00148 1.6e-236 ytoI K transcriptional regulator containing CBS domains
IHFHMFKI_00149 1.5e-46 ytpI S YtpI-like protein
IHFHMFKI_00150 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
IHFHMFKI_00151 5.8e-23
IHFHMFKI_00152 4.3e-86 ytrI
IHFHMFKI_00153 3.2e-56 ytrH S Sporulation protein YtrH
IHFHMFKI_00154 0.0 dnaE 2.7.7.7 L DNA polymerase
IHFHMFKI_00155 2.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
IHFHMFKI_00156 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IHFHMFKI_00157 5.3e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
IHFHMFKI_00158 2e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IHFHMFKI_00159 7.5e-295 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IHFHMFKI_00160 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
IHFHMFKI_00161 6.9e-193 ytvI S sporulation integral membrane protein YtvI
IHFHMFKI_00162 1.1e-72 yeaL S membrane
IHFHMFKI_00163 2.1e-46 yjdF S Protein of unknown function (DUF2992)
IHFHMFKI_00164 1.6e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
IHFHMFKI_00165 1.2e-241 icd 1.1.1.42 C isocitrate
IHFHMFKI_00166 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
IHFHMFKI_00167 5.3e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_00168 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
IHFHMFKI_00169 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IHFHMFKI_00170 4.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IHFHMFKI_00171 6.8e-105 ytaF P Probably functions as a manganese efflux pump
IHFHMFKI_00172 2.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IHFHMFKI_00173 7.6e-160 ytbE S reductase
IHFHMFKI_00174 4.5e-206 ytbD EGP Major facilitator Superfamily
IHFHMFKI_00175 2e-67 ytcD K Transcriptional regulator
IHFHMFKI_00176 1.1e-194 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IHFHMFKI_00177 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
IHFHMFKI_00178 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IHFHMFKI_00179 9.1e-251 dnaB L Membrane attachment protein
IHFHMFKI_00180 9.5e-172 dnaI L Primosomal protein DnaI
IHFHMFKI_00181 4.3e-107 ytxB S SNARE associated Golgi protein
IHFHMFKI_00182 6.7e-153 ytxC S YtxC-like family
IHFHMFKI_00183 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHFHMFKI_00184 5.1e-150 ysaA S HAD-hyrolase-like
IHFHMFKI_00185 0.0 lytS 2.7.13.3 T Histidine kinase
IHFHMFKI_00186 2.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
IHFHMFKI_00187 2.9e-38 lrgA S effector of murein hydrolase LrgA
IHFHMFKI_00188 5.4e-108 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
IHFHMFKI_00189 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IHFHMFKI_00190 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IHFHMFKI_00191 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IHFHMFKI_00192 2.6e-42 ysdA S Membrane
IHFHMFKI_00193 1.9e-65 ysdB S Sigma-w pathway protein YsdB
IHFHMFKI_00194 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
IHFHMFKI_00195 2e-188 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IHFHMFKI_00196 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
IHFHMFKI_00197 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
IHFHMFKI_00198 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
IHFHMFKI_00199 7.8e-141 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
IHFHMFKI_00200 8e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
IHFHMFKI_00201 2.9e-251 araN G carbohydrate transport
IHFHMFKI_00202 6.4e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
IHFHMFKI_00203 1.2e-144 araQ G transport system permease
IHFHMFKI_00204 8.6e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
IHFHMFKI_00205 0.0 cstA T Carbon starvation protein
IHFHMFKI_00206 8.9e-256 glcF C Glycolate oxidase
IHFHMFKI_00207 1.6e-258 glcD 1.1.3.15 C FAD binding domain
IHFHMFKI_00208 2.7e-202 ysfB KT regulator
IHFHMFKI_00209 2e-32 sspI S Belongs to the SspI family
IHFHMFKI_00210 3.7e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHFHMFKI_00211 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IHFHMFKI_00212 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IHFHMFKI_00213 6.4e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHFHMFKI_00214 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IHFHMFKI_00215 3.6e-83 cvpA S membrane protein, required for colicin V production
IHFHMFKI_00216 0.0 polX L COG1796 DNA polymerase IV (family X)
IHFHMFKI_00217 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IHFHMFKI_00218 4.7e-67 yshE S membrane
IHFHMFKI_00219 1.6e-115 ywbB S Protein of unknown function (DUF2711)
IHFHMFKI_00220 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IHFHMFKI_00221 2.7e-103 fadR K Transcriptional regulator
IHFHMFKI_00222 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IHFHMFKI_00223 1.7e-137 etfB C Electron transfer flavoprotein
IHFHMFKI_00224 6e-177 etfA C Electron transfer flavoprotein
IHFHMFKI_00225 6.2e-298 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
IHFHMFKI_00226 2.5e-52 trxA O Belongs to the thioredoxin family
IHFHMFKI_00227 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IHFHMFKI_00228 9.2e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IHFHMFKI_00229 2e-79 yslB S Protein of unknown function (DUF2507)
IHFHMFKI_00230 4.8e-108 sdhC C succinate dehydrogenase
IHFHMFKI_00231 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IHFHMFKI_00232 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
IHFHMFKI_00233 2.7e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
IHFHMFKI_00234 2e-30 gerE K Transcriptional regulator
IHFHMFKI_00235 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
IHFHMFKI_00236 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IHFHMFKI_00237 5.3e-198 gerM S COG5401 Spore germination protein
IHFHMFKI_00238 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IHFHMFKI_00239 9.5e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IHFHMFKI_00240 5.9e-91 ysnB S Phosphoesterase
IHFHMFKI_00245 0.0 ilvB 2.2.1.6 E Acetolactate synthase
IHFHMFKI_00246 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
IHFHMFKI_00247 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IHFHMFKI_00248 1.3e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IHFHMFKI_00249 1.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
IHFHMFKI_00250 1.1e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHFHMFKI_00251 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IHFHMFKI_00252 3.9e-187 ysoA H Tetratricopeptide repeat
IHFHMFKI_00253 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IHFHMFKI_00254 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IHFHMFKI_00255 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
IHFHMFKI_00256 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IHFHMFKI_00257 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
IHFHMFKI_00258 3.8e-87 ysxD
IHFHMFKI_00259 7.7e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IHFHMFKI_00260 1e-145 hemX O cytochrome C
IHFHMFKI_00261 3.5e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
IHFHMFKI_00262 3.6e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IHFHMFKI_00263 3.9e-184 hemB 4.2.1.24 H Belongs to the ALAD family
IHFHMFKI_00264 2.8e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IHFHMFKI_00265 3.3e-231 spoVID M stage VI sporulation protein D
IHFHMFKI_00266 9.5e-197 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IHFHMFKI_00267 2.1e-25
IHFHMFKI_00268 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IHFHMFKI_00269 3.1e-237 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IHFHMFKI_00270 1.1e-130 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
IHFHMFKI_00271 2.2e-134 spoIIB S Sporulation related domain
IHFHMFKI_00272 2.1e-97 maf D septum formation protein Maf
IHFHMFKI_00273 5.3e-127 radC E Belongs to the UPF0758 family
IHFHMFKI_00274 4e-184 mreB D Rod shape-determining protein MreB
IHFHMFKI_00275 3.6e-157 mreC M Involved in formation and maintenance of cell shape
IHFHMFKI_00276 5.4e-84 mreD M shape-determining protein
IHFHMFKI_00277 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IHFHMFKI_00278 2.3e-142 minD D Belongs to the ParA family
IHFHMFKI_00279 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
IHFHMFKI_00280 3e-159 spoIVFB S Stage IV sporulation protein
IHFHMFKI_00281 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
IHFHMFKI_00282 9.2e-56 ysxB J ribosomal protein
IHFHMFKI_00283 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IHFHMFKI_00284 1.3e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
IHFHMFKI_00285 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IHFHMFKI_00286 1.1e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
IHFHMFKI_00287 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
IHFHMFKI_00288 8.7e-93 niaR S small molecule binding protein (contains 3H domain)
IHFHMFKI_00289 3.6e-221 nifS 2.8.1.7 E Cysteine desulfurase
IHFHMFKI_00290 1.1e-294 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
IHFHMFKI_00291 7.6e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
IHFHMFKI_00292 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IHFHMFKI_00293 2.1e-115 safA M spore coat assembly protein SafA
IHFHMFKI_00294 3.2e-48 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IHFHMFKI_00296 3.7e-93 bofC S BofC C-terminal domain
IHFHMFKI_00297 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IHFHMFKI_00298 6.2e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IHFHMFKI_00299 2.8e-20 yrzS S Protein of unknown function (DUF2905)
IHFHMFKI_00300 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IHFHMFKI_00301 4e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IHFHMFKI_00302 2.5e-37 yajC U Preprotein translocase subunit YajC
IHFHMFKI_00303 2.4e-60 yrzE S Protein of unknown function (DUF3792)
IHFHMFKI_00304 9.5e-110 yrbG S membrane
IHFHMFKI_00305 4.6e-272 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IHFHMFKI_00306 8.5e-50 yrzD S Post-transcriptional regulator
IHFHMFKI_00307 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IHFHMFKI_00308 2.1e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
IHFHMFKI_00309 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
IHFHMFKI_00310 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IHFHMFKI_00311 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IHFHMFKI_00312 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IHFHMFKI_00313 1.8e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IHFHMFKI_00314 8.5e-274 lytH 3.5.1.28 M COG3103 SH3 domain protein
IHFHMFKI_00317 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
IHFHMFKI_00318 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IHFHMFKI_00319 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
IHFHMFKI_00320 8.2e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
IHFHMFKI_00321 7.8e-64 cymR K Transcriptional regulator
IHFHMFKI_00322 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
IHFHMFKI_00323 3.2e-222 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IHFHMFKI_00324 1.7e-18 S COG0457 FOG TPR repeat
IHFHMFKI_00325 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IHFHMFKI_00326 3.4e-82 yrrD S protein conserved in bacteria
IHFHMFKI_00327 2.9e-30 yrzR
IHFHMFKI_00328 2.1e-08 S Protein of unknown function (DUF3918)
IHFHMFKI_00329 2.9e-106 glnP P ABC transporter
IHFHMFKI_00330 6.1e-109 gluC P ABC transporter
IHFHMFKI_00331 1.2e-146 glnH ET Belongs to the bacterial solute-binding protein 3 family
IHFHMFKI_00332 7.8e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IHFHMFKI_00333 2e-162 yrrI S AI-2E family transporter
IHFHMFKI_00334 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IHFHMFKI_00335 8.5e-41 yrzL S Belongs to the UPF0297 family
IHFHMFKI_00336 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IHFHMFKI_00337 7.1e-46 yrzB S Belongs to the UPF0473 family
IHFHMFKI_00338 4.1e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHFHMFKI_00339 2.3e-116 yrrM 2.1.1.104 S O-methyltransferase
IHFHMFKI_00340 1.7e-173 yegQ O Peptidase U32
IHFHMFKI_00341 6.1e-246 yegQ O COG0826 Collagenase and related proteases
IHFHMFKI_00342 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
IHFHMFKI_00343 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IHFHMFKI_00344 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
IHFHMFKI_00345 8.1e-70 yrrS S Protein of unknown function (DUF1510)
IHFHMFKI_00346 4.1e-27 yrzA S Protein of unknown function (DUF2536)
IHFHMFKI_00347 2.3e-116 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
IHFHMFKI_00348 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IHFHMFKI_00349 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
IHFHMFKI_00350 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IHFHMFKI_00351 5.1e-34 yrhC S YrhC-like protein
IHFHMFKI_00352 7e-81 yrhD S Protein of unknown function (DUF1641)
IHFHMFKI_00353 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
IHFHMFKI_00354 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
IHFHMFKI_00355 8e-143 focA P Formate nitrite
IHFHMFKI_00357 7.1e-79 yrhH Q methyltransferase
IHFHMFKI_00358 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
IHFHMFKI_00359 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IHFHMFKI_00360 1.9e-212 ynfM EGP Major facilitator Superfamily
IHFHMFKI_00361 2e-163 yybE K Transcriptional regulator
IHFHMFKI_00362 1.7e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IHFHMFKI_00363 1.9e-180 romA S Beta-lactamase superfamily domain
IHFHMFKI_00364 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
IHFHMFKI_00365 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
IHFHMFKI_00366 1.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
IHFHMFKI_00367 5.9e-129 glvR K Helix-turn-helix domain, rpiR family
IHFHMFKI_00368 7.3e-144 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
IHFHMFKI_00369 4.2e-144 S hydrolase
IHFHMFKI_00370 8.9e-92 yrdA S DinB family
IHFHMFKI_00371 1.4e-79 yyaR K Acetyltransferase (GNAT) domain
IHFHMFKI_00372 1.1e-219 tetL EGP Major facilitator Superfamily
IHFHMFKI_00373 2.8e-22 yyaR K acetyltransferase
IHFHMFKI_00374 9.9e-97 adk 2.7.4.3 F adenylate kinase activity
IHFHMFKI_00376 1e-146 ydeE K AraC family transcriptional regulator
IHFHMFKI_00377 3.6e-91 K Transcriptional regulator PadR-like family
IHFHMFKI_00378 1.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
IHFHMFKI_00379 1.5e-124 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHFHMFKI_00380 4.5e-209 EGP Major facilitator Superfamily
IHFHMFKI_00381 8e-106 yqeD S SNARE associated Golgi protein
IHFHMFKI_00382 2.9e-139 3.5.1.104 G Polysaccharide deacetylase
IHFHMFKI_00383 7.2e-138 yqeF E GDSL-like Lipase/Acylhydrolase
IHFHMFKI_00385 7.6e-94 yqeG S hydrolase of the HAD superfamily
IHFHMFKI_00386 1.3e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
IHFHMFKI_00387 2.4e-158 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IHFHMFKI_00388 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
IHFHMFKI_00389 2.1e-105 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IHFHMFKI_00390 1.8e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
IHFHMFKI_00391 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IHFHMFKI_00392 2.1e-137 yqeM Q Methyltransferase
IHFHMFKI_00393 3.8e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHFHMFKI_00394 1.1e-102 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
IHFHMFKI_00395 8e-105 comEB 3.5.4.12 F ComE operon protein 2
IHFHMFKI_00396 0.0 comEC S Competence protein ComEC
IHFHMFKI_00397 7.2e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
IHFHMFKI_00398 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
IHFHMFKI_00399 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IHFHMFKI_00400 9.2e-220 spoIIP M stage II sporulation protein P
IHFHMFKI_00401 2.5e-53 yqxA S Protein of unknown function (DUF3679)
IHFHMFKI_00402 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IHFHMFKI_00403 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
IHFHMFKI_00404 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IHFHMFKI_00405 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IHFHMFKI_00406 0.0 dnaK O Heat shock 70 kDa protein
IHFHMFKI_00407 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IHFHMFKI_00408 6.6e-173 prmA J Methylates ribosomal protein L11
IHFHMFKI_00409 3.9e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IHFHMFKI_00410 3.5e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
IHFHMFKI_00411 5.6e-156 yqeW P COG1283 Na phosphate symporter
IHFHMFKI_00412 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IHFHMFKI_00413 8e-68 yqeY S Yqey-like protein
IHFHMFKI_00414 4.9e-230 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
IHFHMFKI_00415 3.8e-118 yqfA S UPF0365 protein
IHFHMFKI_00416 1.5e-50 yqfB
IHFHMFKI_00417 9.3e-46 yqfC S sporulation protein YqfC
IHFHMFKI_00418 5.7e-214 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
IHFHMFKI_00419 6.6e-176 phoH T Phosphate starvation-inducible protein PhoH
IHFHMFKI_00420 0.0 yqfF S membrane-associated HD superfamily hydrolase
IHFHMFKI_00421 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IHFHMFKI_00422 1.3e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IHFHMFKI_00423 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
IHFHMFKI_00424 2e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IHFHMFKI_00425 1.8e-16 S YqzL-like protein
IHFHMFKI_00426 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
IHFHMFKI_00427 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IHFHMFKI_00428 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IHFHMFKI_00429 4.5e-112 ccpN K CBS domain
IHFHMFKI_00430 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IHFHMFKI_00431 1.3e-87 yaiI S Belongs to the UPF0178 family
IHFHMFKI_00432 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IHFHMFKI_00433 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IHFHMFKI_00434 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
IHFHMFKI_00435 2.9e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
IHFHMFKI_00436 1.4e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IHFHMFKI_00437 3.2e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IHFHMFKI_00438 1.7e-40 yqfQ S YqfQ-like protein
IHFHMFKI_00439 6.8e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IHFHMFKI_00440 1.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IHFHMFKI_00441 9.3e-37 yqfT S Protein of unknown function (DUF2624)
IHFHMFKI_00442 5.9e-155 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IHFHMFKI_00443 2.9e-72 zur P Belongs to the Fur family
IHFHMFKI_00444 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
IHFHMFKI_00445 2.3e-52 yqfX S membrane
IHFHMFKI_00446 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IHFHMFKI_00447 3.1e-47 yqfZ M LysM domain
IHFHMFKI_00448 2.4e-128 yqgB S Protein of unknown function (DUF1189)
IHFHMFKI_00449 2.9e-71 yqgC S protein conserved in bacteria
IHFHMFKI_00450 6.9e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
IHFHMFKI_00451 3.4e-228 yqgE EGP Major facilitator superfamily
IHFHMFKI_00452 0.0 pbpA 3.4.16.4 M penicillin-binding protein
IHFHMFKI_00453 8.4e-157 pstS P Phosphate
IHFHMFKI_00454 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
IHFHMFKI_00455 2.9e-154 pstA P Phosphate transport system permease
IHFHMFKI_00456 8e-143 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHFHMFKI_00457 7.5e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IHFHMFKI_00458 1.1e-75 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IHFHMFKI_00459 1.2e-50 yqzD
IHFHMFKI_00460 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IHFHMFKI_00461 4.6e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IHFHMFKI_00462 4e-07 yqgO
IHFHMFKI_00463 1.5e-212 nhaC C Na H antiporter
IHFHMFKI_00464 2.2e-179 glcK 2.7.1.2 G Glucokinase
IHFHMFKI_00465 2e-216 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
IHFHMFKI_00466 1.1e-197 yqgU
IHFHMFKI_00467 4.5e-49 yqgV S Thiamine-binding protein
IHFHMFKI_00468 1.2e-19 yqgW S Protein of unknown function (DUF2759)
IHFHMFKI_00469 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
IHFHMFKI_00470 3.1e-37 yqgY S Protein of unknown function (DUF2626)
IHFHMFKI_00471 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
IHFHMFKI_00473 6.5e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IHFHMFKI_00474 2.8e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IHFHMFKI_00475 4.5e-185 corA P Mg2 transporter protein
IHFHMFKI_00476 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IHFHMFKI_00477 4.6e-183 comGB NU COG1459 Type II secretory pathway, component PulF
IHFHMFKI_00478 8.9e-50 comGC U Required for transformation and DNA binding
IHFHMFKI_00479 5.8e-71 gspH NU Tfp pilus assembly protein FimT
IHFHMFKI_00480 2.6e-20 comGE
IHFHMFKI_00481 1.6e-64 comGF U Putative Competence protein ComGF
IHFHMFKI_00482 1e-60 S ComG operon protein 7
IHFHMFKI_00483 2.3e-26 yqzE S YqzE-like protein
IHFHMFKI_00484 3.2e-53 yqzG S Protein of unknown function (DUF3889)
IHFHMFKI_00485 2.7e-120 yqxM
IHFHMFKI_00486 1.9e-69 sipW 3.4.21.89 U Signal peptidase
IHFHMFKI_00487 4.7e-140 tasA S Cell division protein FtsN
IHFHMFKI_00488 7.8e-55 sinR K transcriptional
IHFHMFKI_00489 5.2e-23 sinI S Anti-repressor SinI
IHFHMFKI_00490 5.5e-152 yqhG S Bacterial protein YqhG of unknown function
IHFHMFKI_00491 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IHFHMFKI_00492 2.8e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
IHFHMFKI_00493 3e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IHFHMFKI_00494 3.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IHFHMFKI_00495 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
IHFHMFKI_00496 3.4e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
IHFHMFKI_00497 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
IHFHMFKI_00498 3.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
IHFHMFKI_00499 5.8e-62 yqhP
IHFHMFKI_00500 8e-174 yqhQ S Protein of unknown function (DUF1385)
IHFHMFKI_00501 3.7e-88 yqhR S Conserved membrane protein YqhR
IHFHMFKI_00502 3.3e-176 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IHFHMFKI_00503 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IHFHMFKI_00504 1.8e-36 yqhV S Protein of unknown function (DUF2619)
IHFHMFKI_00505 2.1e-171 spoIIIAA S stage III sporulation protein AA
IHFHMFKI_00506 1.6e-83 spoIIIAB S Stage III sporulation protein
IHFHMFKI_00507 7.6e-29 spoIIIAC S stage III sporulation protein AC
IHFHMFKI_00508 2.5e-41 spoIIIAD S Stage III sporulation protein AD
IHFHMFKI_00509 6.3e-200 spoIIIAE S stage III sporulation protein AE
IHFHMFKI_00510 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
IHFHMFKI_00511 1.9e-116 spoIIIAG S stage III sporulation protein AG
IHFHMFKI_00512 4.3e-62 spoIIIAH S SpoIIIAH-like protein
IHFHMFKI_00513 4.6e-61 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IHFHMFKI_00514 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
IHFHMFKI_00515 8.1e-67 yqhY S protein conserved in bacteria
IHFHMFKI_00516 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IHFHMFKI_00517 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IHFHMFKI_00518 1.3e-243 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHFHMFKI_00519 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IHFHMFKI_00520 8.8e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IHFHMFKI_00521 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IHFHMFKI_00522 1.3e-154 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
IHFHMFKI_00523 3.9e-78 argR K Regulates arginine biosynthesis genes
IHFHMFKI_00524 0.0 recN L May be involved in recombinational repair of damaged DNA
IHFHMFKI_00525 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
IHFHMFKI_00526 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
IHFHMFKI_00527 4.1e-212 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHFHMFKI_00530 1.2e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
IHFHMFKI_00532 3.4e-112 K Protein of unknown function (DUF1232)
IHFHMFKI_00533 3.4e-101 ytaF P Probably functions as a manganese efflux pump
IHFHMFKI_00534 4.2e-17
IHFHMFKI_00535 2.3e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
IHFHMFKI_00536 8.1e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IHFHMFKI_00537 2.4e-212 mmgA 2.3.1.9 I Belongs to the thiolase family
IHFHMFKI_00538 2.5e-155 hbdA 1.1.1.157 I Dehydrogenase
IHFHMFKI_00539 5.3e-201 mmgC I acyl-CoA dehydrogenase
IHFHMFKI_00540 1.9e-203 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
IHFHMFKI_00541 2.7e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
IHFHMFKI_00542 2.4e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IHFHMFKI_00543 3.2e-34 yqzF S Protein of unknown function (DUF2627)
IHFHMFKI_00544 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
IHFHMFKI_00545 2.3e-151 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
IHFHMFKI_00546 2.4e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
IHFHMFKI_00547 5.9e-205 buk 2.7.2.7 C Belongs to the acetokinase family
IHFHMFKI_00548 1e-265 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IHFHMFKI_00549 1.1e-160 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IHFHMFKI_00550 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IHFHMFKI_00551 1.2e-188 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IHFHMFKI_00552 2.3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IHFHMFKI_00553 1e-75 yqiW S Belongs to the UPF0403 family
IHFHMFKI_00554 3.4e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
IHFHMFKI_00555 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
IHFHMFKI_00556 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IHFHMFKI_00557 1.4e-170 yqjA S Putative aromatic acid exporter C-terminal domain
IHFHMFKI_00558 1.2e-94 yqjB S protein conserved in bacteria
IHFHMFKI_00560 9.4e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
IHFHMFKI_00561 1.1e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IHFHMFKI_00562 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
IHFHMFKI_00563 5e-148 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHFHMFKI_00564 2.4e-25 yqzJ
IHFHMFKI_00565 4.7e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHFHMFKI_00566 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IHFHMFKI_00567 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IHFHMFKI_00568 2.3e-170 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IHFHMFKI_00569 2.6e-10 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IHFHMFKI_00570 1.3e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
IHFHMFKI_00571 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
IHFHMFKI_00572 1.6e-49 S GlpM protein
IHFHMFKI_00573 3e-159 K LysR substrate binding domain
IHFHMFKI_00574 7.7e-94 nusG K Participates in transcription elongation, termination and antitermination
IHFHMFKI_00575 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IHFHMFKI_00578 1.7e-246 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IHFHMFKI_00579 1.1e-127 IQ reductase
IHFHMFKI_00580 0.0 pksJ Q Polyketide synthase of type I
IHFHMFKI_00581 0.0 1.1.1.320 Q Polyketide synthase of type I
IHFHMFKI_00582 0.0 Q Polyketide synthase of type I
IHFHMFKI_00583 0.0 pksJ Q Polyketide synthase of type I
IHFHMFKI_00584 0.0 pfaA Q Polyketide synthase of type I
IHFHMFKI_00585 0.0 Q Polyketide synthase of type I
IHFHMFKI_00586 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IHFHMFKI_00587 2e-219 eryK 1.14.13.154 C Cytochrome P450
IHFHMFKI_00588 3.7e-238 pksG 2.3.3.10 I synthase
IHFHMFKI_00589 3.3e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IHFHMFKI_00590 4e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHFHMFKI_00591 4e-173 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
IHFHMFKI_00592 1e-139 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
IHFHMFKI_00593 1.4e-248 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IHFHMFKI_00594 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IHFHMFKI_00595 2.8e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IHFHMFKI_00597 3.9e-185 yueF S transporter activity
IHFHMFKI_00599 2.1e-55 S YolD-like protein
IHFHMFKI_00600 6.1e-235 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IHFHMFKI_00601 8.7e-89 yqjY K acetyltransferase
IHFHMFKI_00602 9.6e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
IHFHMFKI_00603 7.6e-172 yqkA K GrpB protein
IHFHMFKI_00604 7.7e-61 yqkB S Belongs to the HesB IscA family
IHFHMFKI_00605 3.2e-39 yqkC S Protein of unknown function (DUF2552)
IHFHMFKI_00606 9e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
IHFHMFKI_00608 2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
IHFHMFKI_00610 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
IHFHMFKI_00611 4e-220 yqxK 3.6.4.12 L DNA helicase
IHFHMFKI_00612 1e-57 ansR K Transcriptional regulator
IHFHMFKI_00613 2.9e-187 ansA 3.5.1.1 EJ L-asparaginase
IHFHMFKI_00614 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
IHFHMFKI_00615 1.6e-239 mleN C Na H antiporter
IHFHMFKI_00616 4.2e-242 mleA 1.1.1.38 C malic enzyme
IHFHMFKI_00617 5.7e-22
IHFHMFKI_00618 1e-31 yqkK
IHFHMFKI_00620 1.2e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
IHFHMFKI_00621 1.9e-80 fur P Belongs to the Fur family
IHFHMFKI_00622 3.7e-37 S Protein of unknown function (DUF4227)
IHFHMFKI_00623 2.8e-165 xerD L recombinase XerD
IHFHMFKI_00624 3.3e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
IHFHMFKI_00625 5.5e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IHFHMFKI_00626 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
IHFHMFKI_00627 6.6e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
IHFHMFKI_00628 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
IHFHMFKI_00629 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHFHMFKI_00630 4.8e-111 spoVAA S Stage V sporulation protein AA
IHFHMFKI_00631 5.1e-60 spoVAB S Stage V sporulation protein AB
IHFHMFKI_00632 6e-79 spoVAC S stage V sporulation protein AC
IHFHMFKI_00633 1.2e-188 spoVAD I Stage V sporulation protein AD
IHFHMFKI_00634 5e-57 spoVAEB S stage V sporulation protein
IHFHMFKI_00635 5.2e-110 spoVAEA S stage V sporulation protein
IHFHMFKI_00636 3.2e-270 spoVAF EG Stage V sporulation protein AF
IHFHMFKI_00637 3e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IHFHMFKI_00638 1.9e-153 ypuA S Secreted protein
IHFHMFKI_00639 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IHFHMFKI_00640 1.2e-80 ccdC1 O Protein of unknown function (DUF1453)
IHFHMFKI_00641 8.4e-99 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IHFHMFKI_00642 6.4e-49 ypuD
IHFHMFKI_00643 3.1e-209 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IHFHMFKI_00644 2.2e-111 ribE 2.5.1.9 H Riboflavin synthase
IHFHMFKI_00645 3.2e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IHFHMFKI_00646 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IHFHMFKI_00647 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHFHMFKI_00648 2.9e-93 ypuF S Domain of unknown function (DUF309)
IHFHMFKI_00650 8.9e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IHFHMFKI_00651 1.7e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IHFHMFKI_00652 3.8e-93 ypuI S Protein of unknown function (DUF3907)
IHFHMFKI_00653 6.6e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
IHFHMFKI_00654 2e-103 spmA S Spore maturation protein
IHFHMFKI_00655 1.3e-88 spmB S Spore maturation protein
IHFHMFKI_00656 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IHFHMFKI_00657 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
IHFHMFKI_00658 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
IHFHMFKI_00659 1.2e-192 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
IHFHMFKI_00660 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_00661 0.0 resE 2.7.13.3 T Histidine kinase
IHFHMFKI_00662 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
IHFHMFKI_00663 5.7e-192 rsiX
IHFHMFKI_00664 9.7e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHFHMFKI_00665 1.9e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IHFHMFKI_00666 3.6e-41 fer C Ferredoxin
IHFHMFKI_00667 1.1e-192 ypbB 5.1.3.1 S protein conserved in bacteria
IHFHMFKI_00668 5.2e-270 recQ 3.6.4.12 L DNA helicase
IHFHMFKI_00669 4e-99 ypbD S metal-dependent membrane protease
IHFHMFKI_00670 1.3e-73 ypbE M Lysin motif
IHFHMFKI_00671 5.7e-85 ypbF S Protein of unknown function (DUF2663)
IHFHMFKI_00672 1.3e-145 ypbG S Calcineurin-like phosphoesterase superfamily domain
IHFHMFKI_00673 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IHFHMFKI_00674 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IHFHMFKI_00675 3.4e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
IHFHMFKI_00676 4.1e-121 prsW S Involved in the degradation of specific anti-sigma factors
IHFHMFKI_00677 3e-159 sleB 3.5.1.28 M Spore cortex-lytic enzyme
IHFHMFKI_00678 3e-251 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
IHFHMFKI_00679 1.8e-60 ypfA M Flagellar protein YcgR
IHFHMFKI_00680 1.4e-12 S Family of unknown function (DUF5359)
IHFHMFKI_00681 9.5e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IHFHMFKI_00682 1.5e-206 rpsA 1.17.7.4 J Ribosomal protein S1
IHFHMFKI_00683 1.7e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IHFHMFKI_00684 4.7e-08 S YpzI-like protein
IHFHMFKI_00685 7.2e-104 yphA
IHFHMFKI_00686 4.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IHFHMFKI_00687 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IHFHMFKI_00688 3.3e-16 yphE S Protein of unknown function (DUF2768)
IHFHMFKI_00689 3.1e-133 yphF
IHFHMFKI_00690 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
IHFHMFKI_00691 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IHFHMFKI_00692 2.1e-100 folE 3.5.4.16 H GTP cyclohydrolase
IHFHMFKI_00693 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
IHFHMFKI_00694 1.2e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
IHFHMFKI_00695 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IHFHMFKI_00696 7.4e-197 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IHFHMFKI_00697 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
IHFHMFKI_00698 1.1e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
IHFHMFKI_00699 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IHFHMFKI_00700 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IHFHMFKI_00701 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
IHFHMFKI_00702 1.9e-289 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHFHMFKI_00703 4e-155 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IHFHMFKI_00704 2.8e-129 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IHFHMFKI_00705 7.5e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IHFHMFKI_00706 1.2e-227 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IHFHMFKI_00707 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IHFHMFKI_00708 6.4e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IHFHMFKI_00709 3.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IHFHMFKI_00710 8.1e-238 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IHFHMFKI_00711 3.5e-233 S COG0457 FOG TPR repeat
IHFHMFKI_00712 2.1e-99 ypiB S Belongs to the UPF0302 family
IHFHMFKI_00713 3.2e-77 ypiF S Protein of unknown function (DUF2487)
IHFHMFKI_00714 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
IHFHMFKI_00715 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
IHFHMFKI_00716 1.1e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
IHFHMFKI_00717 3.2e-104 ypjA S membrane
IHFHMFKI_00718 9.5e-141 ypjB S sporulation protein
IHFHMFKI_00719 2.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
IHFHMFKI_00720 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
IHFHMFKI_00721 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
IHFHMFKI_00722 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IHFHMFKI_00723 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
IHFHMFKI_00724 1.9e-132 bshB1 S proteins, LmbE homologs
IHFHMFKI_00725 2.4e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
IHFHMFKI_00726 7.8e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IHFHMFKI_00727 1.6e-182 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IHFHMFKI_00728 1.6e-146 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
IHFHMFKI_00729 7.2e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IHFHMFKI_00730 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
IHFHMFKI_00731 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IHFHMFKI_00732 6.7e-23 ypmA S Protein of unknown function (DUF4264)
IHFHMFKI_00733 1.5e-80 ypmB S protein conserved in bacteria
IHFHMFKI_00734 6.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IHFHMFKI_00735 9.9e-252 asnS 6.1.1.22 J asparaginyl-tRNA
IHFHMFKI_00736 3e-130 dnaD L DNA replication protein DnaD
IHFHMFKI_00737 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IHFHMFKI_00738 5.7e-91 ypoC
IHFHMFKI_00739 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHFHMFKI_00740 1.8e-110 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IHFHMFKI_00741 3.4e-188 yppC S Protein of unknown function (DUF2515)
IHFHMFKI_00744 3.3e-11 yppE S Bacterial domain of unknown function (DUF1798)
IHFHMFKI_00746 2.1e-49 yppG S YppG-like protein
IHFHMFKI_00747 2.1e-70 hspX O Belongs to the small heat shock protein (HSP20) family
IHFHMFKI_00748 1e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
IHFHMFKI_00749 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
IHFHMFKI_00750 1.6e-219 yprB L RNase_H superfamily
IHFHMFKI_00752 9.9e-33 cotD S Inner spore coat protein D
IHFHMFKI_00753 1.1e-98 ypsA S Belongs to the UPF0398 family
IHFHMFKI_00754 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IHFHMFKI_00755 2.7e-216 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IHFHMFKI_00756 6.6e-22 S YpzG-like protein
IHFHMFKI_00758 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
IHFHMFKI_00759 1.3e-290 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IHFHMFKI_00760 3.1e-96 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IHFHMFKI_00761 3.2e-234 pbuX F xanthine
IHFHMFKI_00762 3.6e-139 L Belongs to the 'phage' integrase family
IHFHMFKI_00763 2.7e-16 K Helix-turn-helix XRE-family like proteins
IHFHMFKI_00764 1.3e-32
IHFHMFKI_00765 8.5e-43 S Phage regulatory protein Rha (Phage_pRha)
IHFHMFKI_00766 5.8e-87
IHFHMFKI_00770 7.3e-100
IHFHMFKI_00771 1.7e-61 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
IHFHMFKI_00773 2.1e-78 3.1.3.16 L DnaD domain protein
IHFHMFKI_00774 6.3e-118 xkdC L IstB-like ATP binding protein
IHFHMFKI_00776 2.2e-59 rusA L Endodeoxyribonuclease RusA
IHFHMFKI_00778 3.4e-21 yqaO S Phage-like element PBSX protein XtrA
IHFHMFKI_00784 7.8e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IHFHMFKI_00786 4.6e-13 K Transcriptional regulator
IHFHMFKI_00788 1.4e-17 K Transcriptional regulator
IHFHMFKI_00792 2.2e-77 L phage terminase small subunit
IHFHMFKI_00793 1.2e-300 S Terminase
IHFHMFKI_00794 4.2e-170 S Phage portal protein
IHFHMFKI_00795 1.5e-83 S peptidase activity
IHFHMFKI_00796 6.6e-155 gp36 S capsid protein
IHFHMFKI_00797 3.3e-23
IHFHMFKI_00798 4.5e-38 S Phage gp6-like head-tail connector protein
IHFHMFKI_00799 2.9e-40 S Phage head-tail joining protein
IHFHMFKI_00800 7.4e-49 S Bacteriophage HK97-gp10, putative tail-component
IHFHMFKI_00802 5.1e-81 S Phage tail tube protein
IHFHMFKI_00804 0.0 D phage tail tape measure protein
IHFHMFKI_00805 2.5e-102 S Phage tail protein
IHFHMFKI_00806 1.5e-228 NU Prophage endopeptidase tail
IHFHMFKI_00807 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
IHFHMFKI_00808 2.5e-99
IHFHMFKI_00809 1.2e-08
IHFHMFKI_00811 3.8e-59 S Pfam:Phage_holin_4_1
IHFHMFKI_00812 2.2e-69 S N-acetylmuramoyl-L-alanine amidase activity
IHFHMFKI_00813 2e-86 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IHFHMFKI_00814 1.4e-22
IHFHMFKI_00816 1.6e-25 K Helix-turn-helix domain
IHFHMFKI_00817 1.5e-72 S Protein of unknown function (DUF3800)
IHFHMFKI_00819 1.9e-98 yrdC 3.5.1.19 Q Isochorismatase family
IHFHMFKI_00820 9.8e-33 ydfR S Protein of unknown function (DUF421)
IHFHMFKI_00821 8.7e-22 ydfR S Protein of unknown function (DUF421)
IHFHMFKI_00823 6e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IHFHMFKI_00824 6.6e-105 J Acetyltransferase (GNAT) domain
IHFHMFKI_00825 6.1e-202 bcsA Q Naringenin-chalcone synthase
IHFHMFKI_00826 1.1e-89 ypbQ S protein conserved in bacteria
IHFHMFKI_00827 0.0 ypbR S Dynamin family
IHFHMFKI_00828 2.2e-38 ypbS S Protein of unknown function (DUF2533)
IHFHMFKI_00830 3.5e-163 polA 2.7.7.7 L 5'3' exonuclease
IHFHMFKI_00832 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
IHFHMFKI_00833 2e-118 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IHFHMFKI_00834 9.1e-124 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
IHFHMFKI_00835 1.5e-28 ypeQ S Zinc-finger
IHFHMFKI_00836 1.2e-36 S Protein of unknown function (DUF2564)
IHFHMFKI_00837 1.3e-11 degR
IHFHMFKI_00838 1e-30 cspD K Cold-shock protein
IHFHMFKI_00839 1.1e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
IHFHMFKI_00840 1.3e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IHFHMFKI_00841 7.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IHFHMFKI_00842 3.1e-99 ypgQ S phosphohydrolase
IHFHMFKI_00843 4.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
IHFHMFKI_00844 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
IHFHMFKI_00845 1.1e-74 yphP S Belongs to the UPF0403 family
IHFHMFKI_00846 1.1e-130 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
IHFHMFKI_00847 8.5e-113 ypjP S YpjP-like protein
IHFHMFKI_00848 8.7e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IHFHMFKI_00849 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IHFHMFKI_00850 6.1e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IHFHMFKI_00851 1.6e-109 hlyIII S protein, Hemolysin III
IHFHMFKI_00852 8.3e-174 pspF K Transcriptional regulator
IHFHMFKI_00853 3.7e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IHFHMFKI_00854 4.1e-37 ypmP S Protein of unknown function (DUF2535)
IHFHMFKI_00855 4.3e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
IHFHMFKI_00856 6.4e-134 ypmR E GDSL-like Lipase/Acylhydrolase
IHFHMFKI_00857 1.8e-96 ypmS S protein conserved in bacteria
IHFHMFKI_00858 1.4e-66 ypoP K transcriptional
IHFHMFKI_00859 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IHFHMFKI_00860 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IHFHMFKI_00861 2.6e-103 4.2.1.115 GM Polysaccharide biosynthesis protein
IHFHMFKI_00862 4.2e-303 yokA L Recombinase
IHFHMFKI_00864 2.7e-77 yokH G SMI1 / KNR4 family
IHFHMFKI_00865 2.8e-289 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
IHFHMFKI_00866 7.5e-53 S SMI1-KNR4 cell-wall
IHFHMFKI_00867 1.5e-87 yokK S SMI1 / KNR4 family
IHFHMFKI_00868 6.6e-30 S Acetyltransferase (GNAT) domain
IHFHMFKI_00869 7e-24
IHFHMFKI_00870 2.6e-08 S Domain of unknown function (DUF4879)
IHFHMFKI_00872 4.8e-113 3.4.24.40 S amine dehydrogenase activity
IHFHMFKI_00875 5e-207 S aspartate phosphatase
IHFHMFKI_00876 3.1e-75 yoqH M LysM domain
IHFHMFKI_00879 2.6e-08
IHFHMFKI_00880 6.1e-19 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
IHFHMFKI_00881 1.7e-77
IHFHMFKI_00887 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
IHFHMFKI_00888 1.5e-219 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
IHFHMFKI_00889 3.4e-164 cgeB S Spore maturation protein
IHFHMFKI_00890 7.8e-52 cgeA
IHFHMFKI_00891 1.2e-40 cgeC
IHFHMFKI_00892 2e-241 cgeD M maturation of the outermost layer of the spore
IHFHMFKI_00893 1.4e-144 yiiD K acetyltransferase
IHFHMFKI_00895 2e-63 yosT L Bacterial transcription activator, effector binding domain
IHFHMFKI_00896 1.1e-245 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IHFHMFKI_00897 2.2e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IHFHMFKI_00898 2.7e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IHFHMFKI_00899 9e-253 yodQ 3.5.1.16 E Acetylornithine deacetylase
IHFHMFKI_00900 1.9e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
IHFHMFKI_00901 3.6e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
IHFHMFKI_00902 9.2e-46 yokU S YokU-like protein, putative antitoxin
IHFHMFKI_00903 9.1e-36 yozE S Belongs to the UPF0346 family
IHFHMFKI_00904 1.7e-125 yodN
IHFHMFKI_00906 6.2e-24 yozD S YozD-like protein
IHFHMFKI_00907 2.3e-102 yodM 3.6.1.27 I Acid phosphatase homologues
IHFHMFKI_00908 3.3e-55 yodL S YodL-like
IHFHMFKI_00910 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
IHFHMFKI_00911 8.7e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IHFHMFKI_00912 6.5e-22 yodI
IHFHMFKI_00913 2.8e-128 yodH Q Methyltransferase
IHFHMFKI_00914 5.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IHFHMFKI_00915 2.6e-132 yydK K Transcriptional regulator
IHFHMFKI_00916 1.5e-288 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHFHMFKI_00917 1.7e-279 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
IHFHMFKI_00918 3.6e-253 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHFHMFKI_00919 1.4e-19 S Protein of unknown function (DUF3311)
IHFHMFKI_00920 1e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
IHFHMFKI_00921 6.3e-108 mhqD S Carboxylesterase
IHFHMFKI_00922 1.7e-105 yodC C nitroreductase
IHFHMFKI_00923 3e-56 yodB K transcriptional
IHFHMFKI_00924 2.3e-68 yoaQ S Evidence 4 Homologs of previously reported genes of
IHFHMFKI_00925 5.9e-67 yodA S tautomerase
IHFHMFKI_00927 7.3e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
IHFHMFKI_00928 1.1e-161 rarD S -transporter
IHFHMFKI_00929 1.4e-22
IHFHMFKI_00930 3.7e-60 yojF S Protein of unknown function (DUF1806)
IHFHMFKI_00931 5.6e-126 yojG S deacetylase
IHFHMFKI_00932 2.2e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IHFHMFKI_00933 4.7e-236 norM V Multidrug efflux pump
IHFHMFKI_00935 1.7e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHFHMFKI_00936 6.9e-223 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
IHFHMFKI_00937 4.4e-225 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IHFHMFKI_00938 2.1e-108 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IHFHMFKI_00939 1.6e-163 yojN S ATPase family associated with various cellular activities (AAA)
IHFHMFKI_00940 0.0 yojO P Von Willebrand factor
IHFHMFKI_00941 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
IHFHMFKI_00942 5.5e-183 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
IHFHMFKI_00943 1.1e-138 S Metallo-beta-lactamase superfamily
IHFHMFKI_00944 2.5e-159 yocS S -transporter
IHFHMFKI_00945 7.4e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IHFHMFKI_00946 2.1e-165 sodA 1.15.1.1 P Superoxide dismutase
IHFHMFKI_00947 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
IHFHMFKI_00948 4.4e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
IHFHMFKI_00949 3.6e-31 yozC
IHFHMFKI_00951 2.4e-56 yozO S Bacterial PH domain
IHFHMFKI_00952 8.5e-37 yocN
IHFHMFKI_00953 3.8e-44 yozN
IHFHMFKI_00954 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
IHFHMFKI_00955 7.5e-09
IHFHMFKI_00956 1e-09 yocL
IHFHMFKI_00957 9.5e-54 dksA T general stress protein
IHFHMFKI_00959 2.2e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IHFHMFKI_00960 0.0 recQ 3.6.4.12 L DNA helicase
IHFHMFKI_00961 6.5e-114 yocH CBM50 M COG1388 FOG LysM repeat
IHFHMFKI_00963 2.4e-186 yocD 3.4.17.13 V peptidase S66
IHFHMFKI_00964 1.6e-93 yocC
IHFHMFKI_00965 3.4e-138 yocB J Protein required for attachment to host cells
IHFHMFKI_00966 3.6e-91 yozB S membrane
IHFHMFKI_00967 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IHFHMFKI_00968 1.7e-54 czrA K transcriptional
IHFHMFKI_00969 7.1e-92 yobW
IHFHMFKI_00970 2.7e-134 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
IHFHMFKI_00971 1.1e-93 yobS K Transcriptional regulator
IHFHMFKI_00972 4.3e-132 yobQ K helix_turn_helix, arabinose operon control protein
IHFHMFKI_00973 1.2e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
IHFHMFKI_00974 1.3e-60 ykvN K Transcriptional regulator
IHFHMFKI_00975 1.9e-130 IQ Enoyl-(Acyl carrier protein) reductase
IHFHMFKI_00976 7.4e-43
IHFHMFKI_00977 1.5e-95 hpr K helix_turn_helix multiple antibiotic resistance protein
IHFHMFKI_00978 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IHFHMFKI_00979 9.6e-194 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHFHMFKI_00980 1e-265 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
IHFHMFKI_00981 4.8e-203 yoaB EGP Major facilitator Superfamily
IHFHMFKI_00982 6.4e-134 yoxB
IHFHMFKI_00983 1.6e-38 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IHFHMFKI_00984 1.1e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IHFHMFKI_00985 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
IHFHMFKI_00986 2.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IHFHMFKI_00987 6.2e-202 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHFHMFKI_00988 4.5e-150 gltC K Transcriptional regulator
IHFHMFKI_00989 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
IHFHMFKI_00990 1.5e-291 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
IHFHMFKI_00991 1.1e-183 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
IHFHMFKI_00992 1.2e-152 gltR1 K Transcriptional regulator
IHFHMFKI_00993 1.7e-13 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IHFHMFKI_00994 1.8e-50 ybzH K Helix-turn-helix domain
IHFHMFKI_00995 5.2e-199 ybcL EGP Major facilitator Superfamily
IHFHMFKI_00996 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IHFHMFKI_00997 1.8e-34 yoeD G Helix-turn-helix domain
IHFHMFKI_00998 3.5e-97 L Integrase
IHFHMFKI_01000 2.9e-96 yoeB S IseA DL-endopeptidase inhibitor
IHFHMFKI_01001 6.7e-246 yoeA V MATE efflux family protein
IHFHMFKI_01002 7.8e-185 yoxA 5.1.3.3 G Aldose 1-epimerase
IHFHMFKI_01003 1.9e-267 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
IHFHMFKI_01004 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_01005 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_01006 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_01007 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_01008 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
IHFHMFKI_01009 1.6e-64 yngL S Protein of unknown function (DUF1360)
IHFHMFKI_01010 7.3e-302 yngK T Glycosyl hydrolase-like 10
IHFHMFKI_01011 5.4e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
IHFHMFKI_01012 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
IHFHMFKI_01013 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
IHFHMFKI_01014 6e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
IHFHMFKI_01015 6.8e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
IHFHMFKI_01016 1.5e-138 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
IHFHMFKI_01017 2.2e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
IHFHMFKI_01018 3.2e-104 yngC S SNARE associated Golgi protein
IHFHMFKI_01019 7.5e-158 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IHFHMFKI_01020 1.2e-67 yngA S membrane
IHFHMFKI_01021 1.5e-143 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
IHFHMFKI_01022 3.3e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
IHFHMFKI_01023 1.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IHFHMFKI_01024 9.2e-127 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IHFHMFKI_01025 3.7e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IHFHMFKI_01026 5.6e-217 bioI 1.14.14.46 C Cytochrome P450
IHFHMFKI_01027 4.2e-251 yxjC EG COG2610 H gluconate symporter and related permeases
IHFHMFKI_01028 9.9e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IHFHMFKI_01029 2.4e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
IHFHMFKI_01030 2.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IHFHMFKI_01031 1.3e-216 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IHFHMFKI_01032 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_01033 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_01034 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_01035 4.7e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
IHFHMFKI_01036 2.4e-250 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
IHFHMFKI_01037 4.6e-126 T Transcriptional regulatory protein, C terminal
IHFHMFKI_01038 3.1e-227 T PhoQ Sensor
IHFHMFKI_01039 1.2e-49 S Domain of unknown function (DUF4870)
IHFHMFKI_01040 1.3e-284 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
IHFHMFKI_01041 2.9e-17 S Platelet-activating factor acetylhydrolase, isoform II
IHFHMFKI_01042 2.1e-33 S Platelet-activating factor acetylhydrolase, isoform II
IHFHMFKI_01043 1.7e-296 yndJ S YndJ-like protein
IHFHMFKI_01044 5.6e-80 yndH S Domain of unknown function (DUF4166)
IHFHMFKI_01045 5.4e-155 yndG S DoxX-like family
IHFHMFKI_01046 1.4e-39 exuT G Sugar (and other) transporter
IHFHMFKI_01047 1e-179 kdgR_1 K transcriptional
IHFHMFKI_01048 1.8e-145 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IHFHMFKI_01049 6e-210 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
IHFHMFKI_01050 1.5e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
IHFHMFKI_01051 6.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
IHFHMFKI_01052 5.7e-180 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
IHFHMFKI_01053 1.2e-245 agcS E Sodium alanine symporter
IHFHMFKI_01054 5.1e-41 ynfC
IHFHMFKI_01055 6e-13
IHFHMFKI_01056 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHFHMFKI_01057 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IHFHMFKI_01058 1.5e-68 yccU S CoA-binding protein
IHFHMFKI_01059 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IHFHMFKI_01060 1.1e-49 yneR S Belongs to the HesB IscA family
IHFHMFKI_01061 1.4e-52 yneQ
IHFHMFKI_01062 8.3e-75 yneP S Thioesterase-like superfamily
IHFHMFKI_01063 7.1e-18 tlp S Belongs to the Tlp family
IHFHMFKI_01066 1.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IHFHMFKI_01067 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IHFHMFKI_01068 7.5e-15 sspO S Belongs to the SspO family
IHFHMFKI_01069 2.3e-19 sspP S Belongs to the SspP family
IHFHMFKI_01070 1.4e-62 hspX O Spore coat protein
IHFHMFKI_01071 5.5e-74 yneK S Protein of unknown function (DUF2621)
IHFHMFKI_01072 9.6e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
IHFHMFKI_01073 4.7e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
IHFHMFKI_01074 1.7e-125 ccdA O cytochrome c biogenesis protein
IHFHMFKI_01075 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
IHFHMFKI_01076 2.3e-28 yneF S UPF0154 protein
IHFHMFKI_01077 1.3e-81 yneE S Sporulation inhibitor of replication protein sirA
IHFHMFKI_01078 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IHFHMFKI_01079 9.8e-33 ynzC S UPF0291 protein
IHFHMFKI_01080 3.5e-112 yneB L resolvase
IHFHMFKI_01081 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
IHFHMFKI_01082 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IHFHMFKI_01083 2.1e-12 yoaW
IHFHMFKI_01084 1.2e-71 yndM S Protein of unknown function (DUF2512)
IHFHMFKI_01085 1.6e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
IHFHMFKI_01086 9.1e-08
IHFHMFKI_01087 1e-140 yndL S Replication protein
IHFHMFKI_01088 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
IHFHMFKI_01089 0.0 yobO M Pectate lyase superfamily protein
IHFHMFKI_01091 8.7e-93 yvgO
IHFHMFKI_01094 4.5e-117 AA10,CBM73 S Pfam:Chitin_bind_3
IHFHMFKI_01095 3.9e-201 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHFHMFKI_01096 2.8e-114 ynaE S Domain of unknown function (DUF3885)
IHFHMFKI_01097 1.6e-99 J Acetyltransferase (GNAT) domain
IHFHMFKI_01098 2.1e-131 yoaP 3.1.3.18 K YoaP-like
IHFHMFKI_01100 1e-09
IHFHMFKI_01101 3.1e-184 adhP 1.1.1.1 C alcohol dehydrogenase
IHFHMFKI_01105 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
IHFHMFKI_01106 6e-285 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
IHFHMFKI_01107 1.2e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
IHFHMFKI_01108 7.3e-206 xylR GK ROK family
IHFHMFKI_01109 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
IHFHMFKI_01110 4.9e-249 xynT G MFS/sugar transport protein
IHFHMFKI_01111 4.3e-208 mrjp G Major royal jelly protein
IHFHMFKI_01112 4.1e-261 glnA 6.3.1.2 E glutamine synthetase
IHFHMFKI_01113 4.3e-68 glnR K transcriptional
IHFHMFKI_01114 2.4e-242 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
IHFHMFKI_01115 7.2e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IHFHMFKI_01116 1.3e-176 spoVK O stage V sporulation protein K
IHFHMFKI_01117 1.6e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IHFHMFKI_01118 1.6e-85 ymaB S MutT family
IHFHMFKI_01119 4.7e-185 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHFHMFKI_01120 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IHFHMFKI_01121 3.9e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
IHFHMFKI_01122 1.8e-20 ymzA
IHFHMFKI_01123 1.8e-41
IHFHMFKI_01124 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
IHFHMFKI_01125 4.8e-171 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IHFHMFKI_01126 9.2e-47 ymaF S YmaF family
IHFHMFKI_01128 2.6e-47 ebrA P Small Multidrug Resistance protein
IHFHMFKI_01129 2.6e-53 ebrB P Small Multidrug Resistance protein
IHFHMFKI_01130 6e-79 ymaD O redox protein, regulator of disulfide bond formation
IHFHMFKI_01131 3e-125 ymaC S Replication protein
IHFHMFKI_01132 1.7e-254 aprX O Belongs to the peptidase S8 family
IHFHMFKI_01133 3.5e-61 ymzB
IHFHMFKI_01134 3.6e-118 yoaK S Membrane
IHFHMFKI_01135 1.9e-77 nucB M Deoxyribonuclease NucA/NucB
IHFHMFKI_01136 1.3e-229 cypA C Cytochrome P450
IHFHMFKI_01137 0.0 pks13 HQ Beta-ketoacyl synthase
IHFHMFKI_01138 0.0 dhbF IQ polyketide synthase
IHFHMFKI_01139 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
IHFHMFKI_01140 0.0 Q Polyketide synthase of type I
IHFHMFKI_01141 0.0 rhiB IQ polyketide synthase
IHFHMFKI_01142 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
IHFHMFKI_01143 1.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
IHFHMFKI_01144 5.3e-242 pksG 2.3.3.10 I synthase
IHFHMFKI_01145 5.5e-34 acpK IQ Phosphopantetheine attachment site
IHFHMFKI_01146 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IHFHMFKI_01147 1.1e-183 pksD Q Acyl transferase domain
IHFHMFKI_01148 2.4e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IHFHMFKI_01149 1.3e-128 pksB 3.1.2.6 S Polyketide biosynthesis
IHFHMFKI_01152 2.4e-33
IHFHMFKI_01153 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IHFHMFKI_01154 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IHFHMFKI_01155 1.7e-88 cotE S Spore coat protein
IHFHMFKI_01156 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
IHFHMFKI_01157 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IHFHMFKI_01158 2.6e-214 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
IHFHMFKI_01159 4.5e-194 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
IHFHMFKI_01160 1.2e-36 spoVS S Stage V sporulation protein S
IHFHMFKI_01161 4.9e-153 ymdB S protein conserved in bacteria
IHFHMFKI_01162 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
IHFHMFKI_01163 1.1e-193 pbpX V Beta-lactamase
IHFHMFKI_01164 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IHFHMFKI_01165 9.3e-231 cinA 3.5.1.42 S Belongs to the CinA family
IHFHMFKI_01166 1.4e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHFHMFKI_01167 4.1e-124 ymfM S protein conserved in bacteria
IHFHMFKI_01168 1e-142 ymfK S Protein of unknown function (DUF3388)
IHFHMFKI_01169 2.2e-41 ymfJ S Protein of unknown function (DUF3243)
IHFHMFKI_01170 1.2e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
IHFHMFKI_01171 3.5e-241 ymfH S zinc protease
IHFHMFKI_01172 8.9e-237 ymfF S Peptidase M16
IHFHMFKI_01173 0.0 ydgH S drug exporters of the RND superfamily
IHFHMFKI_01174 2.1e-76 K helix_turn_helix multiple antibiotic resistance protein
IHFHMFKI_01175 3e-227 ymfD EGP Major facilitator Superfamily
IHFHMFKI_01176 1.2e-132 ymfC K Transcriptional regulator
IHFHMFKI_01177 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IHFHMFKI_01178 6.3e-31 S YlzJ-like protein
IHFHMFKI_01179 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
IHFHMFKI_01180 2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHFHMFKI_01181 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IHFHMFKI_01182 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
IHFHMFKI_01183 4.9e-193 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IHFHMFKI_01184 5.7e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
IHFHMFKI_01185 1e-159 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
IHFHMFKI_01186 2.6e-42 ymxH S YlmC YmxH family
IHFHMFKI_01187 1.2e-233 pepR S Belongs to the peptidase M16 family
IHFHMFKI_01188 2e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
IHFHMFKI_01189 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
IHFHMFKI_01190 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IHFHMFKI_01191 4.6e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IHFHMFKI_01192 8e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IHFHMFKI_01193 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IHFHMFKI_01194 3.9e-44 ylxP S protein conserved in bacteria
IHFHMFKI_01195 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IHFHMFKI_01196 1.8e-47 ylxQ J ribosomal protein
IHFHMFKI_01197 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
IHFHMFKI_01198 5.4e-206 nusA K Participates in both transcription termination and antitermination
IHFHMFKI_01199 2.5e-80 rimP S Required for maturation of 30S ribosomal subunits
IHFHMFKI_01200 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHFHMFKI_01201 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IHFHMFKI_01202 5.9e-233 rasP M zinc metalloprotease
IHFHMFKI_01203 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
IHFHMFKI_01204 2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
IHFHMFKI_01205 1.4e-144 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IHFHMFKI_01206 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IHFHMFKI_01207 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IHFHMFKI_01208 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IHFHMFKI_01209 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
IHFHMFKI_01210 8e-50 ylxL
IHFHMFKI_01211 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHFHMFKI_01212 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
IHFHMFKI_01213 1.8e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
IHFHMFKI_01214 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
IHFHMFKI_01215 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
IHFHMFKI_01216 2.5e-192 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
IHFHMFKI_01217 2.4e-156 flhG D Belongs to the ParA family
IHFHMFKI_01218 2.2e-191 flhF N Flagellar biosynthesis regulator FlhF
IHFHMFKI_01219 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IHFHMFKI_01220 5.3e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IHFHMFKI_01221 5.2e-131 fliR N Flagellar biosynthetic protein FliR
IHFHMFKI_01222 2e-37 fliQ N Role in flagellar biosynthesis
IHFHMFKI_01223 2.2e-109 fliP N Plays a role in the flagellum-specific transport system
IHFHMFKI_01224 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
IHFHMFKI_01225 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
IHFHMFKI_01226 4e-188 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IHFHMFKI_01227 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IHFHMFKI_01228 2.4e-58 fliL N Controls the rotational direction of flagella during chemotaxis
IHFHMFKI_01229 5.7e-138 flgG N Flagellar basal body rod
IHFHMFKI_01230 2.4e-72 flgD N Flagellar basal body rod modification protein
IHFHMFKI_01231 7.5e-202 fliK N Flagellar hook-length control protein
IHFHMFKI_01232 1.3e-47 ylxF S MgtE intracellular N domain
IHFHMFKI_01233 2e-71 fliJ N Flagellar biosynthesis chaperone
IHFHMFKI_01234 8.5e-243 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
IHFHMFKI_01235 1.5e-87 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
IHFHMFKI_01236 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
IHFHMFKI_01237 1.4e-263 fliF N The M ring may be actively involved in energy transduction
IHFHMFKI_01238 1.3e-30 fliE N Flagellar hook-basal body
IHFHMFKI_01239 8.1e-76 flgC N Belongs to the flagella basal body rod proteins family
IHFHMFKI_01240 3e-55 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
IHFHMFKI_01241 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
IHFHMFKI_01242 4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IHFHMFKI_01243 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IHFHMFKI_01244 7.2e-172 xerC L tyrosine recombinase XerC
IHFHMFKI_01245 2.2e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IHFHMFKI_01246 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHFHMFKI_01247 1.6e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
IHFHMFKI_01248 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IHFHMFKI_01249 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
IHFHMFKI_01250 8.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
IHFHMFKI_01251 6.6e-304 ylqG
IHFHMFKI_01252 1.5e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IHFHMFKI_01253 3.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IHFHMFKI_01254 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IHFHMFKI_01255 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IHFHMFKI_01256 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IHFHMFKI_01257 1.3e-61 ylqD S YlqD protein
IHFHMFKI_01258 1.7e-35 ylqC S Belongs to the UPF0109 family
IHFHMFKI_01259 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IHFHMFKI_01260 7.6e-223 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IHFHMFKI_01261 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IHFHMFKI_01262 3e-139 S Phosphotransferase enzyme family
IHFHMFKI_01263 1.1e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IHFHMFKI_01264 0.0 smc D Required for chromosome condensation and partitioning
IHFHMFKI_01265 3.7e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IHFHMFKI_01266 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IHFHMFKI_01267 4.6e-129 IQ reductase
IHFHMFKI_01268 7.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IHFHMFKI_01269 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IHFHMFKI_01270 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
IHFHMFKI_01271 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IHFHMFKI_01272 1.3e-154 sdaAA 4.3.1.17 E L-serine dehydratase
IHFHMFKI_01273 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
IHFHMFKI_01274 4.9e-304 yloV S kinase related to dihydroxyacetone kinase
IHFHMFKI_01275 5.5e-59 asp S protein conserved in bacteria
IHFHMFKI_01276 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IHFHMFKI_01277 1.3e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
IHFHMFKI_01278 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IHFHMFKI_01279 4.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IHFHMFKI_01280 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IHFHMFKI_01281 2.3e-139 stp 3.1.3.16 T phosphatase
IHFHMFKI_01282 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
IHFHMFKI_01283 7.9e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IHFHMFKI_01284 6.8e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IHFHMFKI_01285 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHFHMFKI_01286 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHFHMFKI_01287 3.3e-225 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IHFHMFKI_01288 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IHFHMFKI_01289 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IHFHMFKI_01290 1.5e-40 ylzA S Belongs to the UPF0296 family
IHFHMFKI_01291 8.5e-154 yloC S stress-induced protein
IHFHMFKI_01292 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
IHFHMFKI_01293 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
IHFHMFKI_01294 5.5e-78 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
IHFHMFKI_01295 1.6e-143 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
IHFHMFKI_01296 2.2e-142 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IHFHMFKI_01297 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
IHFHMFKI_01298 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
IHFHMFKI_01299 1.1e-176 cysP P phosphate transporter
IHFHMFKI_01300 3.8e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
IHFHMFKI_01302 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IHFHMFKI_01303 2.1e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IHFHMFKI_01304 2.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IHFHMFKI_01305 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
IHFHMFKI_01306 0.0 carB 6.3.5.5 F Belongs to the CarB family
IHFHMFKI_01307 7.2e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IHFHMFKI_01308 3.6e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IHFHMFKI_01309 5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IHFHMFKI_01310 3e-232 pyrP F Xanthine uracil
IHFHMFKI_01311 1.4e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IHFHMFKI_01312 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHFHMFKI_01313 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IHFHMFKI_01314 1.2e-61 dksA T COG1734 DnaK suppressor protein
IHFHMFKI_01315 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IHFHMFKI_01316 8.9e-68 divIVA D Cell division initiation protein
IHFHMFKI_01317 6.1e-140 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
IHFHMFKI_01318 5.2e-41 yggT S membrane
IHFHMFKI_01319 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IHFHMFKI_01320 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IHFHMFKI_01321 3.7e-159 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
IHFHMFKI_01322 2.2e-38 ylmC S sporulation protein
IHFHMFKI_01323 8.7e-249 argE 3.5.1.16 E Acetylornithine deacetylase
IHFHMFKI_01324 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
IHFHMFKI_01325 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHFHMFKI_01326 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHFHMFKI_01327 3.7e-160 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
IHFHMFKI_01328 0.0 bpr O COG1404 Subtilisin-like serine proteases
IHFHMFKI_01329 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IHFHMFKI_01330 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IHFHMFKI_01331 4.8e-132 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IHFHMFKI_01332 1.8e-167 murB 1.3.1.98 M cell wall formation
IHFHMFKI_01333 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IHFHMFKI_01334 2.2e-185 spoVE D Belongs to the SEDS family
IHFHMFKI_01335 6.5e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IHFHMFKI_01336 1.1e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IHFHMFKI_01337 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IHFHMFKI_01338 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
IHFHMFKI_01339 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IHFHMFKI_01340 2.9e-52 ftsL D Essential cell division protein
IHFHMFKI_01341 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IHFHMFKI_01342 1.2e-77 mraZ K Belongs to the MraZ family
IHFHMFKI_01343 2.6e-305 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
IHFHMFKI_01344 3.6e-163 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IHFHMFKI_01345 2e-88 ylbP K n-acetyltransferase
IHFHMFKI_01346 3.4e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
IHFHMFKI_01347 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IHFHMFKI_01348 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
IHFHMFKI_01349 5.6e-228 ylbM S Belongs to the UPF0348 family
IHFHMFKI_01350 1.6e-188 ylbL T Belongs to the peptidase S16 family
IHFHMFKI_01351 2e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
IHFHMFKI_01352 6.3e-216 ylbJ S Sporulation integral membrane protein YlbJ
IHFHMFKI_01353 4e-81 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IHFHMFKI_01354 2.7e-97 rsmD 2.1.1.171 L Methyltransferase
IHFHMFKI_01356 5.5e-43 ylbG S UPF0298 protein
IHFHMFKI_01357 1.2e-71 ylbF S Belongs to the UPF0342 family
IHFHMFKI_01358 8.8e-37 ylbE S YlbE-like protein
IHFHMFKI_01359 2.1e-54 ylbD S Putative coat protein
IHFHMFKI_01360 2.3e-198 ylbC S protein with SCP PR1 domains
IHFHMFKI_01361 2.2e-73 ylbB T COG0517 FOG CBS domain
IHFHMFKI_01362 3.2e-59 ylbA S YugN-like family
IHFHMFKI_01363 2e-163 ctaG S cytochrome c oxidase
IHFHMFKI_01364 1.9e-50 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
IHFHMFKI_01365 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
IHFHMFKI_01366 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IHFHMFKI_01367 1.2e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
IHFHMFKI_01368 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IHFHMFKI_01369 1.7e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
IHFHMFKI_01370 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IHFHMFKI_01371 1.9e-212 ftsW D Belongs to the SEDS family
IHFHMFKI_01372 8.7e-44 ylaN S Belongs to the UPF0358 family
IHFHMFKI_01373 1.3e-173 glsA 3.5.1.2 E Belongs to the glutaminase family
IHFHMFKI_01374 8.5e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
IHFHMFKI_01375 6e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
IHFHMFKI_01376 2.6e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IHFHMFKI_01377 1.4e-33 ylaI S protein conserved in bacteria
IHFHMFKI_01378 6.6e-48 ylaH S YlaH-like protein
IHFHMFKI_01379 0.0 typA T GTP-binding protein TypA
IHFHMFKI_01380 6.7e-24 S Family of unknown function (DUF5325)
IHFHMFKI_01381 2.3e-36 ylaE
IHFHMFKI_01382 3.7e-13 sigC S Putative zinc-finger
IHFHMFKI_01383 1.2e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
IHFHMFKI_01384 1.9e-43 ylaB
IHFHMFKI_01385 2.2e-186 ylaA
IHFHMFKI_01386 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
IHFHMFKI_01387 4e-83 ykzC S Acetyltransferase (GNAT) family
IHFHMFKI_01388 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
IHFHMFKI_01389 6.3e-24 ykzI
IHFHMFKI_01390 1.8e-118 yktB S Belongs to the UPF0637 family
IHFHMFKI_01391 3.5e-42 yktA S Belongs to the UPF0223 family
IHFHMFKI_01392 2.8e-274 speA 4.1.1.19 E Arginine
IHFHMFKI_01393 3.9e-134 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
IHFHMFKI_01394 1.8e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
IHFHMFKI_01395 1.2e-250 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IHFHMFKI_01396 4.9e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IHFHMFKI_01397 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IHFHMFKI_01398 2.3e-204 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IHFHMFKI_01399 3.3e-208 V Beta-lactamase
IHFHMFKI_01400 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
IHFHMFKI_01401 0.0 Q Polyketide synthase of type I
IHFHMFKI_01402 0.0 Q Polyketide synthase of type I
IHFHMFKI_01403 0.0 Q Polyketide synthase of type I
IHFHMFKI_01404 0.0 Q Polyketide synthase of type I
IHFHMFKI_01405 0.0 Q polyketide synthase
IHFHMFKI_01406 0.0 Q Polyketide synthase of type I
IHFHMFKI_01407 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
IHFHMFKI_01408 2.5e-102 recN L Putative cell-wall binding lipoprotein
IHFHMFKI_01410 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IHFHMFKI_01411 7.4e-146 ykrA S hydrolases of the HAD superfamily
IHFHMFKI_01412 8.2e-31 ykzG S Belongs to the UPF0356 family
IHFHMFKI_01413 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IHFHMFKI_01414 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IHFHMFKI_01415 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
IHFHMFKI_01416 3.8e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
IHFHMFKI_01417 3.4e-244 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
IHFHMFKI_01418 1.8e-44 abrB K of stationary sporulation gene expression
IHFHMFKI_01419 6.9e-184 mreB D Rod-share determining protein MreBH
IHFHMFKI_01420 5.5e-12 S Uncharacterized protein YkpC
IHFHMFKI_01421 1e-234 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
IHFHMFKI_01422 1.7e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IHFHMFKI_01423 1.1e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IHFHMFKI_01424 1.7e-36 ykoA
IHFHMFKI_01425 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
IHFHMFKI_01426 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IHFHMFKI_01427 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
IHFHMFKI_01428 1.7e-131 fruR K Transcriptional regulator
IHFHMFKI_01429 3e-210 yknZ V ABC transporter (permease)
IHFHMFKI_01430 2e-121 macB V ABC transporter, ATP-binding protein
IHFHMFKI_01431 3.9e-167 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IHFHMFKI_01432 4.4e-105 yknW S Yip1 domain
IHFHMFKI_01433 1.7e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IHFHMFKI_01434 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
IHFHMFKI_01435 1.9e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
IHFHMFKI_01436 1.4e-242 moeA 2.10.1.1 H molybdopterin
IHFHMFKI_01437 7.2e-189 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IHFHMFKI_01438 3.7e-108 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
IHFHMFKI_01439 1.8e-160 yknT
IHFHMFKI_01440 4.5e-98 rok K Repressor of ComK
IHFHMFKI_01441 7.4e-77 ykuV CO thiol-disulfide
IHFHMFKI_01442 3.7e-140 ykuT M Mechanosensitive ion channel
IHFHMFKI_01443 4.8e-38 ykuS S Belongs to the UPF0180 family
IHFHMFKI_01444 2.9e-215 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IHFHMFKI_01445 4.5e-73 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IHFHMFKI_01446 2.3e-78 fld C Flavodoxin
IHFHMFKI_01447 5.7e-166 ykuO
IHFHMFKI_01448 1.3e-89 fld C Flavodoxin
IHFHMFKI_01449 1.3e-167 ccpC K Transcriptional regulator
IHFHMFKI_01450 1e-75 ykuL S CBS domain
IHFHMFKI_01451 2.1e-25 ykzF S Antirepressor AbbA
IHFHMFKI_01452 1.4e-92 ykuK S Ribonuclease H-like
IHFHMFKI_01453 3.9e-37 ykuJ S protein conserved in bacteria
IHFHMFKI_01454 3.3e-233 ykuI T Diguanylate phosphodiesterase
IHFHMFKI_01456 1.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_01457 1.4e-153 ykuE S Metallophosphoesterase
IHFHMFKI_01458 4.1e-89 ykuD S protein conserved in bacteria
IHFHMFKI_01459 1.1e-239 ykuC EGP Major facilitator Superfamily
IHFHMFKI_01460 1.4e-83 ykyB S YkyB-like protein
IHFHMFKI_01461 1.8e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
IHFHMFKI_01462 2.3e-09
IHFHMFKI_01463 3.9e-215 patA 2.6.1.1 E Aminotransferase
IHFHMFKI_01464 6.8e-291 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
IHFHMFKI_01465 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
IHFHMFKI_01466 9.8e-114 ykwD J protein with SCP PR1 domains
IHFHMFKI_01467 1.6e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
IHFHMFKI_01468 2.9e-263 mcpC NT chemotaxis protein
IHFHMFKI_01469 1.9e-189 splB 4.1.99.14 L Spore photoproduct lyase
IHFHMFKI_01470 6.1e-38 splA S Transcriptional regulator
IHFHMFKI_01471 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IHFHMFKI_01472 2.1e-39 ptsH G phosphocarrier protein HPr
IHFHMFKI_01473 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IHFHMFKI_01474 5.1e-156 glcT K antiterminator
IHFHMFKI_01475 3.3e-175 ykvZ 5.1.1.1 K Transcriptional regulator
IHFHMFKI_01477 6.9e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
IHFHMFKI_01478 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IHFHMFKI_01479 1.7e-87 stoA CO thiol-disulfide
IHFHMFKI_01480 1.1e-240 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IHFHMFKI_01481 5.3e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
IHFHMFKI_01482 3.9e-27
IHFHMFKI_01483 7.8e-25 ykvS S protein conserved in bacteria
IHFHMFKI_01484 1e-44 ykvR S Protein of unknown function (DUF3219)
IHFHMFKI_01485 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IHFHMFKI_01486 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
IHFHMFKI_01487 1.7e-78 queD 4.1.2.50, 4.2.3.12 H synthase
IHFHMFKI_01488 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IHFHMFKI_01489 1.8e-185
IHFHMFKI_01490 1.3e-182 ykvI S membrane
IHFHMFKI_01491 0.0 clpE O Belongs to the ClpA ClpB family
IHFHMFKI_01492 3.3e-136 motA N flagellar motor
IHFHMFKI_01493 2.7e-127 motB N Flagellar motor protein
IHFHMFKI_01494 5.5e-77 ykvE K transcriptional
IHFHMFKI_01495 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
IHFHMFKI_01496 3.4e-10 S Spo0E like sporulation regulatory protein
IHFHMFKI_01497 4.6e-94 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
IHFHMFKI_01498 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
IHFHMFKI_01499 1.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
IHFHMFKI_01500 2.5e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
IHFHMFKI_01501 3.5e-227 mtnE 2.6.1.83 E Aminotransferase
IHFHMFKI_01502 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IHFHMFKI_01503 7.2e-225 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
IHFHMFKI_01504 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
IHFHMFKI_01506 3.9e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHFHMFKI_01507 0.0 kinE 2.7.13.3 T Histidine kinase
IHFHMFKI_01508 2.1e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
IHFHMFKI_01509 8.7e-23 ykzE
IHFHMFKI_01510 7.2e-113 ydfR S Protein of unknown function (DUF421)
IHFHMFKI_01511 4.8e-241 ktrB P COG0168 Trk-type K transport systems, membrane components
IHFHMFKI_01512 4.5e-155 htpX O Belongs to the peptidase M48B family
IHFHMFKI_01513 8.6e-125 ykrK S Domain of unknown function (DUF1836)
IHFHMFKI_01514 2.5e-26 sspD S small acid-soluble spore protein
IHFHMFKI_01515 1.5e-118 rsgI S Anti-sigma factor N-terminus
IHFHMFKI_01516 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHFHMFKI_01517 1.5e-133 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
IHFHMFKI_01518 6.6e-99 ykoX S membrane-associated protein
IHFHMFKI_01519 4.6e-152 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
IHFHMFKI_01520 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
IHFHMFKI_01521 3.7e-99 ykoP G polysaccharide deacetylase
IHFHMFKI_01522 1.1e-80 ykoM K transcriptional
IHFHMFKI_01523 3.1e-26 ykoL
IHFHMFKI_01524 1.9e-16
IHFHMFKI_01525 5.4e-53 tnrA K transcriptional
IHFHMFKI_01526 3.2e-237 mgtE P Acts as a magnesium transporter
IHFHMFKI_01528 7.4e-244 ydhD M Glycosyl hydrolase
IHFHMFKI_01529 1.3e-97 ykoE S ABC-type cobalt transport system, permease component
IHFHMFKI_01530 1.3e-301 P ABC transporter, ATP-binding protein
IHFHMFKI_01531 1.2e-132 ykoC P Cobalt transport protein
IHFHMFKI_01532 4.3e-147 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IHFHMFKI_01533 5e-176 isp O Belongs to the peptidase S8 family
IHFHMFKI_01534 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IHFHMFKI_01535 2e-121 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
IHFHMFKI_01536 1.2e-214 hcaT 1.5.1.2 EGP Major facilitator Superfamily
IHFHMFKI_01537 1.4e-123 M PFAM Collagen triple helix repeat (20 copies)
IHFHMFKI_01538 3.8e-215 M Glycosyl transferase family 2
IHFHMFKI_01540 3.5e-55 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IHFHMFKI_01541 4.2e-71 ohrB O Organic hydroperoxide resistance protein
IHFHMFKI_01542 1.1e-72 ohrR K COG1846 Transcriptional regulators
IHFHMFKI_01543 2.6e-68 ohrA O Organic hydroperoxide resistance protein
IHFHMFKI_01544 1.3e-224 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IHFHMFKI_01545 1.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IHFHMFKI_01546 3e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
IHFHMFKI_01547 2.9e-48 ykkD P Multidrug resistance protein
IHFHMFKI_01548 1.4e-51 ykkC P Multidrug resistance protein
IHFHMFKI_01549 1.1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IHFHMFKI_01550 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
IHFHMFKI_01551 1.5e-158 ykgA E Amidinotransferase
IHFHMFKI_01552 1.1e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
IHFHMFKI_01553 1.6e-182 ykfD E Belongs to the ABC transporter superfamily
IHFHMFKI_01554 3e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IHFHMFKI_01555 2.4e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
IHFHMFKI_01556 2.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
IHFHMFKI_01557 0.0 dppE E ABC transporter substrate-binding protein
IHFHMFKI_01558 2.9e-190 dppD P Belongs to the ABC transporter superfamily
IHFHMFKI_01559 1.1e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHFHMFKI_01560 1.2e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHFHMFKI_01561 9.3e-155 dppA E D-aminopeptidase
IHFHMFKI_01562 9.7e-278 yubD P Major Facilitator Superfamily
IHFHMFKI_01563 1.2e-204 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHFHMFKI_01564 1.5e-16 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IHFHMFKI_01565 4.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IHFHMFKI_01566 5.7e-305 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IHFHMFKI_01567 3.1e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
IHFHMFKI_01568 1.1e-242 steT E amino acid
IHFHMFKI_01569 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
IHFHMFKI_01570 5.8e-175 pit P phosphate transporter
IHFHMFKI_01571 5.9e-132 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
IHFHMFKI_01572 8.7e-23 spoIISB S Stage II sporulation protein SB
IHFHMFKI_01573 1.6e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IHFHMFKI_01574 1.3e-38 xhlB S SPP1 phage holin
IHFHMFKI_01575 8.7e-38 xhlA S Haemolysin XhlA
IHFHMFKI_01576 2.6e-135 xepA
IHFHMFKI_01577 1.6e-28 xkdX
IHFHMFKI_01579 1.7e-91
IHFHMFKI_01580 1.2e-26
IHFHMFKI_01581 8.5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
IHFHMFKI_01582 6.7e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
IHFHMFKI_01583 4.2e-58 xkdS S Protein of unknown function (DUF2634)
IHFHMFKI_01584 7.2e-32 xkdR S Protein of unknown function (DUF2577)
IHFHMFKI_01585 9.4e-162 xkdQ 3.2.1.96 G NLP P60 protein
IHFHMFKI_01586 3.9e-111 xkdP S Lysin motif
IHFHMFKI_01587 1.7e-203 xkdO L Transglycosylase SLT domain
IHFHMFKI_01588 3.4e-19
IHFHMFKI_01589 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
IHFHMFKI_01590 2e-74 xkdM S Phage tail tube protein
IHFHMFKI_01591 3.5e-226 xkdK S Phage tail sheath C-terminal domain
IHFHMFKI_01592 8.2e-15
IHFHMFKI_01593 3.2e-56 xkdJ
IHFHMFKI_01594 5.3e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
IHFHMFKI_01595 5.5e-43 yqbH S Domain of unknown function (DUF3599)
IHFHMFKI_01596 4.3e-46 yqbG S Protein of unknown function (DUF3199)
IHFHMFKI_01597 4.6e-158 xkdG S Phage capsid family
IHFHMFKI_01598 9.8e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
IHFHMFKI_01599 5.1e-241 yqbA S portal protein
IHFHMFKI_01600 8.5e-211 xtmB S phage terminase, large subunit
IHFHMFKI_01601 3e-110 xtmA L phage terminase small subunit
IHFHMFKI_01602 4.9e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
IHFHMFKI_01603 2e-10 yqaO S Phage-like element PBSX protein XtrA
IHFHMFKI_01606 5.2e-150 xkdC L Bacterial dnaA protein
IHFHMFKI_01608 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
IHFHMFKI_01609 2.9e-110 xkdA E IrrE N-terminal-like domain
IHFHMFKI_01611 6.7e-110 yjqB S phage-related replication protein
IHFHMFKI_01612 8e-61 yjqA S Bacterial PH domain
IHFHMFKI_01613 2.2e-168 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IHFHMFKI_01615 4.9e-215 S response regulator aspartate phosphatase
IHFHMFKI_01616 1.5e-77 yjoA S DinB family
IHFHMFKI_01617 1.5e-130 MA20_18170 S membrane transporter protein
IHFHMFKI_01618 3.4e-204 salB V Domain of unknown function (DUF4135)
IHFHMFKI_01621 1.1e-220 lanT 3.6.3.27 V Peptidase C39 family
IHFHMFKI_01622 8.2e-300 lcnDR2 V Lanthionine synthetase C-like protein
IHFHMFKI_01624 5.4e-60 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHFHMFKI_01625 1.7e-46 narQ 2.7.13.3 T Histidine kinase
IHFHMFKI_01627 2.7e-65 S ABC-2 family transporter protein
IHFHMFKI_01628 8.5e-104 V ABC transporter, ATP-binding protein
IHFHMFKI_01629 1.4e-131 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
IHFHMFKI_01630 4e-87 T Transcriptional regulatory protein, C terminal
IHFHMFKI_01631 1.3e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
IHFHMFKI_01632 2.9e-276 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
IHFHMFKI_01633 7e-181 exuR K transcriptional
IHFHMFKI_01634 2.5e-253 yjmB G symporter YjmB
IHFHMFKI_01635 4.8e-276 uxaC 5.3.1.12 G glucuronate isomerase
IHFHMFKI_01636 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
IHFHMFKI_01637 7e-66 yjlC S Protein of unknown function (DUF1641)
IHFHMFKI_01638 5.7e-91 yjlB S Cupin domain
IHFHMFKI_01639 1.7e-174 yjlA EG Putative multidrug resistance efflux transporter
IHFHMFKI_01640 1.3e-128 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
IHFHMFKI_01641 2.1e-124 ybbM S transport system, permease component
IHFHMFKI_01642 5.8e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
IHFHMFKI_01643 6.8e-29
IHFHMFKI_01644 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IHFHMFKI_01645 4.4e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
IHFHMFKI_01646 4.3e-92 yjgD S Protein of unknown function (DUF1641)
IHFHMFKI_01647 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
IHFHMFKI_01648 1.3e-99 yjgB S Domain of unknown function (DUF4309)
IHFHMFKI_01649 2.3e-66 T PhoQ Sensor
IHFHMFKI_01650 3.7e-21 yjfB S Putative motility protein
IHFHMFKI_01651 8.1e-106 yhiD S MgtC SapB transporter
IHFHMFKI_01653 1e-122 5.4.2.6 S Haloacid dehalogenase-like hydrolase
IHFHMFKI_01654 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
IHFHMFKI_01655 6.9e-283 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
IHFHMFKI_01656 9.1e-50 lacF 2.7.1.207 G phosphotransferase system
IHFHMFKI_01657 6.4e-307 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHFHMFKI_01658 1.1e-212 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IHFHMFKI_01659 1e-184 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IHFHMFKI_01660 3.2e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IHFHMFKI_01661 3.8e-220 ganA 3.2.1.89 G arabinogalactan
IHFHMFKI_01662 5.1e-81 napB K helix_turn_helix multiple antibiotic resistance protein
IHFHMFKI_01663 4.5e-250 yfjF EGP Belongs to the major facilitator superfamily
IHFHMFKI_01664 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
IHFHMFKI_01665 6.3e-160 bla 3.5.2.6 V beta-lactamase
IHFHMFKI_01667 2.9e-58 E Glyoxalase-like domain
IHFHMFKI_01670 1.5e-306 yobL S Bacterial EndoU nuclease
IHFHMFKI_01671 2.6e-21
IHFHMFKI_01673 2.4e-30 S KTSC domain
IHFHMFKI_01674 9.1e-11 NU Prophage endopeptidase tail
IHFHMFKI_01675 2.1e-153 D phage tail tape measure protein
IHFHMFKI_01677 8.4e-11
IHFHMFKI_01682 4.7e-18
IHFHMFKI_01683 5.4e-12 K Helix-turn-helix XRE-family like proteins
IHFHMFKI_01684 8.1e-29
IHFHMFKI_01686 4.1e-119
IHFHMFKI_01688 2.3e-14
IHFHMFKI_01692 4.2e-24
IHFHMFKI_01693 8.7e-13 S Cro/C1-type HTH DNA-binding domain
IHFHMFKI_01696 6.6e-100 L Belongs to the 'phage' integrase family
IHFHMFKI_01697 1.1e-103 S Helix-turn-helix domain
IHFHMFKI_01698 6e-191 L Belongs to the 'phage' integrase family
IHFHMFKI_01700 2.2e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IHFHMFKI_01701 8.7e-212 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IHFHMFKI_01702 3.6e-126 yjcH P COG2382 Enterochelin esterase and related enzymes
IHFHMFKI_01703 1.1e-92 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
IHFHMFKI_01704 2.3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHFHMFKI_01706 2.7e-35 K SpoVT / AbrB like domain
IHFHMFKI_01707 1.3e-131 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
IHFHMFKI_01708 5.7e-124 S ABC-2 type transporter
IHFHMFKI_01709 2.2e-139 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
IHFHMFKI_01710 1.3e-35
IHFHMFKI_01711 0.0 yjcD 3.6.4.12 L DNA helicase
IHFHMFKI_01712 3.8e-38 spoVIF S Stage VI sporulation protein F
IHFHMFKI_01716 1.6e-55 yjcA S Protein of unknown function (DUF1360)
IHFHMFKI_01717 1.4e-52 cotV S Spore Coat Protein X and V domain
IHFHMFKI_01718 6.8e-21 cotW
IHFHMFKI_01719 5.1e-71 cotX S Spore Coat Protein X and V domain
IHFHMFKI_01720 1e-92 cotY S Spore coat protein Z
IHFHMFKI_01721 6.7e-83 cotZ S Spore coat protein
IHFHMFKI_01722 1.5e-88 yjbX S Spore coat protein
IHFHMFKI_01723 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IHFHMFKI_01724 6.4e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IHFHMFKI_01725 4.3e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
IHFHMFKI_01726 7.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
IHFHMFKI_01727 6.7e-30 thiS H Thiamine biosynthesis
IHFHMFKI_01728 1.4e-209 thiO 1.4.3.19 E Glycine oxidase
IHFHMFKI_01729 2.1e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
IHFHMFKI_01730 9.9e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IHFHMFKI_01731 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IHFHMFKI_01732 2.6e-143 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
IHFHMFKI_01733 3.7e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHFHMFKI_01734 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IHFHMFKI_01735 1.1e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
IHFHMFKI_01736 6e-61 yjbL S Belongs to the UPF0738 family
IHFHMFKI_01737 4e-96 yjbK S protein conserved in bacteria
IHFHMFKI_01738 3.5e-115 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
IHFHMFKI_01739 4.8e-72 yjbI S Bacterial-like globin
IHFHMFKI_01740 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IHFHMFKI_01741 5.8e-19
IHFHMFKI_01742 0.0 pepF E oligoendopeptidase F
IHFHMFKI_01743 9.3e-217 yjbF S Competence protein
IHFHMFKI_01744 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
IHFHMFKI_01745 4.7e-109 yjbE P Integral membrane protein TerC family
IHFHMFKI_01746 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IHFHMFKI_01747 4.9e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHFHMFKI_01748 9.8e-230 S Putative glycosyl hydrolase domain
IHFHMFKI_01749 2.3e-170 oppF E Belongs to the ABC transporter superfamily
IHFHMFKI_01750 2.7e-202 oppD P Belongs to the ABC transporter superfamily
IHFHMFKI_01751 1.7e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHFHMFKI_01752 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHFHMFKI_01753 0.0 oppA E ABC transporter substrate-binding protein
IHFHMFKI_01754 2.6e-183 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
IHFHMFKI_01755 6.1e-145 yjbA S Belongs to the UPF0736 family
IHFHMFKI_01756 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHFHMFKI_01757 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHFHMFKI_01758 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
IHFHMFKI_01759 5.9e-188 appF E Belongs to the ABC transporter superfamily
IHFHMFKI_01760 4.8e-182 appD P Belongs to the ABC transporter superfamily
IHFHMFKI_01761 5.6e-149 yjaZ O Zn-dependent protease
IHFHMFKI_01762 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IHFHMFKI_01763 1.5e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHFHMFKI_01764 1e-31 yjzB
IHFHMFKI_01765 1.1e-26 comZ S ComZ
IHFHMFKI_01766 2.7e-165 med S Transcriptional activator protein med
IHFHMFKI_01767 8.8e-104 yjaV
IHFHMFKI_01768 4.6e-137 yjaU I carboxylic ester hydrolase activity
IHFHMFKI_01769 3.3e-23 yjzD S Protein of unknown function (DUF2929)
IHFHMFKI_01770 1.2e-27 yjzC S YjzC-like protein
IHFHMFKI_01771 7.8e-177 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IHFHMFKI_01772 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
IHFHMFKI_01773 2e-202 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IHFHMFKI_01774 4.9e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
IHFHMFKI_01775 7e-136 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IHFHMFKI_01776 1.7e-224 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IHFHMFKI_01777 3.3e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IHFHMFKI_01778 1.2e-89 norB G Major Facilitator Superfamily
IHFHMFKI_01779 3.3e-272 yitY C D-arabinono-1,4-lactone oxidase
IHFHMFKI_01780 5.1e-72 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
IHFHMFKI_01781 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
IHFHMFKI_01782 3.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IHFHMFKI_01783 5.1e-153 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IHFHMFKI_01784 3.5e-07
IHFHMFKI_01785 4.4e-26 S Protein of unknown function (DUF3813)
IHFHMFKI_01786 1.2e-79 ipi S Intracellular proteinase inhibitor
IHFHMFKI_01787 1.5e-147 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
IHFHMFKI_01788 3e-156 yitS S protein conserved in bacteria
IHFHMFKI_01790 9.1e-218 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
IHFHMFKI_01791 1.9e-170 yufN S ABC transporter substrate-binding protein PnrA-like
IHFHMFKI_01792 7.6e-160 cvfB S protein conserved in bacteria
IHFHMFKI_01793 6.6e-55 yajQ S Belongs to the UPF0234 family
IHFHMFKI_01794 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IHFHMFKI_01795 2.4e-80 yjcF S Acetyltransferase (GNAT) domain
IHFHMFKI_01796 1.6e-69 mcbG S Pentapeptide repeats (9 copies)
IHFHMFKI_01797 1.2e-83 yisT S DinB family
IHFHMFKI_01798 5.8e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
IHFHMFKI_01799 9.2e-144 purR K helix_turn _helix lactose operon repressor
IHFHMFKI_01800 2.3e-159 yisR K Transcriptional regulator
IHFHMFKI_01801 1.5e-245 yisQ V Mate efflux family protein
IHFHMFKI_01802 3.6e-129 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
IHFHMFKI_01803 0.0 asnO 6.3.5.4 E Asparagine synthase
IHFHMFKI_01804 3.4e-97 yisN S Protein of unknown function (DUF2777)
IHFHMFKI_01805 3.2e-59 yisL S UPF0344 protein
IHFHMFKI_01806 1.3e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
IHFHMFKI_01807 4.8e-07 yisI S Spo0E like sporulation regulatory protein
IHFHMFKI_01808 8.4e-34 gerPA S Spore germination protein
IHFHMFKI_01809 1.8e-34 gerPB S cell differentiation
IHFHMFKI_01810 1.4e-62 gerPC S Spore germination protein
IHFHMFKI_01811 9.1e-23 gerPD S Spore germination protein
IHFHMFKI_01812 1.1e-63 gerPE S Spore germination protein GerPE
IHFHMFKI_01813 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
IHFHMFKI_01814 1.3e-50 yisB V COG1403 Restriction endonuclease
IHFHMFKI_01815 0.0 sbcC L COG0419 ATPase involved in DNA repair
IHFHMFKI_01816 1.1e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IHFHMFKI_01817 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IHFHMFKI_01818 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
IHFHMFKI_01819 2.5e-119 ydfS S Protein of unknown function (DUF421)
IHFHMFKI_01820 6.3e-93 yhjR S Rubrerythrin
IHFHMFKI_01821 1.1e-107 K QacR-like protein, C-terminal region
IHFHMFKI_01822 3e-202 blt EGP Major facilitator Superfamily
IHFHMFKI_01823 1.2e-187 abrB S membrane
IHFHMFKI_01824 8.4e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
IHFHMFKI_01825 9.2e-270 yhjG CH FAD binding domain
IHFHMFKI_01827 1.6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
IHFHMFKI_01828 7.7e-109 yhjE S SNARE associated Golgi protein
IHFHMFKI_01829 5e-60 yhjD
IHFHMFKI_01830 3.1e-27 yhjC S Protein of unknown function (DUF3311)
IHFHMFKI_01831 3.8e-268 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHFHMFKI_01832 3.3e-47 S Belongs to the UPF0145 family
IHFHMFKI_01833 1.6e-42 yhjA S Excalibur calcium-binding domain
IHFHMFKI_01834 8.7e-125 yrpD S Domain of unknown function, YrpD
IHFHMFKI_01835 6e-61 frataxin S Domain of unknown function (DU1801)
IHFHMFKI_01836 4.7e-66 frataxin S Domain of unknown function (DU1801)
IHFHMFKI_01837 1.9e-109 comK K Competence transcription factor
IHFHMFKI_01838 5.4e-31 yhzC S IDEAL
IHFHMFKI_01839 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_01840 1.6e-296 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
IHFHMFKI_01841 1.2e-196 hemAT NT chemotaxis protein
IHFHMFKI_01842 4.6e-89 bioY S BioY family
IHFHMFKI_01843 4.7e-279 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IHFHMFKI_01844 6.7e-201 vraB 2.3.1.9 I Belongs to the thiolase family
IHFHMFKI_01845 4.4e-103 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
IHFHMFKI_01846 1.6e-149 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
IHFHMFKI_01847 2.2e-202 aprE 3.4.21.62 O Belongs to the peptidase S8 family
IHFHMFKI_01848 3.6e-235 yhfN 3.4.24.84 O Peptidase M48
IHFHMFKI_01849 1.9e-65 yhfM
IHFHMFKI_01850 1.2e-296 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
IHFHMFKI_01851 1.4e-108 yhfK GM NmrA-like family
IHFHMFKI_01852 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
IHFHMFKI_01853 2.2e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
IHFHMFKI_01854 7.9e-11 yhfH S YhfH-like protein
IHFHMFKI_01855 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IHFHMFKI_01856 6.6e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
IHFHMFKI_01858 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IHFHMFKI_01859 4.7e-244 yhgE S YhgE Pip N-terminal domain protein
IHFHMFKI_01860 3.2e-101 yhgD K Transcriptional regulator
IHFHMFKI_01862 7e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
IHFHMFKI_01863 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IHFHMFKI_01864 9.5e-203 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IHFHMFKI_01865 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHFHMFKI_01866 2.4e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IHFHMFKI_01867 6.2e-244 yhfA C membrane
IHFHMFKI_01868 2.2e-221 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
IHFHMFKI_01869 4e-122 ecsC S EcsC protein family
IHFHMFKI_01870 8.5e-221 ecsB U ABC transporter
IHFHMFKI_01871 1.1e-135 ecsA V transporter (ATP-binding protein)
IHFHMFKI_01872 4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
IHFHMFKI_01873 6e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IHFHMFKI_01874 1.4e-76 trpP S Tryptophan transporter TrpP
IHFHMFKI_01875 2e-17
IHFHMFKI_01876 6.2e-39 yhaH S YtxH-like protein
IHFHMFKI_01877 8.6e-113 hpr K Negative regulator of protease production and sporulation
IHFHMFKI_01878 9.9e-55 yhaI S Protein of unknown function (DUF1878)
IHFHMFKI_01879 7e-95 yhaK S Putative zincin peptidase
IHFHMFKI_01880 9.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IHFHMFKI_01881 1.8e-31 yhaL S Sporulation protein YhaL
IHFHMFKI_01882 2.6e-177 yhaM L Shows a 3'-5' exoribonuclease activity
IHFHMFKI_01883 0.0 yhaN L AAA domain
IHFHMFKI_01884 4.7e-235 yhaO L DNA repair exonuclease
IHFHMFKI_01885 1.2e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
IHFHMFKI_01886 4.4e-166 yhaQ S ABC transporter, ATP-binding protein
IHFHMFKI_01887 2.8e-14 S YhzD-like protein
IHFHMFKI_01888 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
IHFHMFKI_01890 3.3e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
IHFHMFKI_01891 2.6e-206 yhaU P COG0475 Kef-type K transport systems, membrane components
IHFHMFKI_01892 2.7e-249 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
IHFHMFKI_01893 2.7e-293 hemZ H coproporphyrinogen III oxidase
IHFHMFKI_01894 4.7e-157 yhaX S haloacid dehalogenase-like hydrolase
IHFHMFKI_01895 1.4e-201 yhaZ L DNA alkylation repair enzyme
IHFHMFKI_01896 4.4e-53 yheA S Belongs to the UPF0342 family
IHFHMFKI_01897 3.6e-205 yheB S Belongs to the UPF0754 family
IHFHMFKI_01898 3.4e-213 yheC HJ YheC/D like ATP-grasp
IHFHMFKI_01899 1.5e-258 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
IHFHMFKI_01900 1.7e-36 yheE S Family of unknown function (DUF5342)
IHFHMFKI_01901 1.3e-28 sspB S spore protein
IHFHMFKI_01903 1.6e-111 yheG GM NAD(P)H-binding
IHFHMFKI_01904 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
IHFHMFKI_01905 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
IHFHMFKI_01907 6.2e-85 T universal stress protein
IHFHMFKI_01908 1.8e-93 ymcC S Membrane
IHFHMFKI_01909 3e-87 pksA K Transcriptional regulator
IHFHMFKI_01910 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
IHFHMFKI_01911 1.1e-155 yheN G deacetylase
IHFHMFKI_01912 2.9e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
IHFHMFKI_01913 3.5e-205 yhdY M Mechanosensitive ion channel
IHFHMFKI_01915 1.8e-125 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IHFHMFKI_01916 3.3e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHFHMFKI_01917 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IHFHMFKI_01918 6e-255 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
IHFHMFKI_01919 4.7e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IHFHMFKI_01920 1.9e-225 yhdR 2.6.1.1 E Aminotransferase
IHFHMFKI_01921 2.8e-70 cueR K transcriptional
IHFHMFKI_01922 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
IHFHMFKI_01923 4.8e-108 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
IHFHMFKI_01924 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
IHFHMFKI_01925 1.3e-201 yhdL S Sigma factor regulator N-terminal
IHFHMFKI_01926 8.1e-45 yhdK S Sigma-M inhibitor protein
IHFHMFKI_01927 3e-195 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
IHFHMFKI_01928 1.2e-250 yhdG E amino acid
IHFHMFKI_01929 5.1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_01930 5.9e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
IHFHMFKI_01931 1.3e-162 citR K Transcriptional regulator
IHFHMFKI_01932 3.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IHFHMFKI_01933 1.3e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
IHFHMFKI_01934 1.8e-270 ycgB S Stage V sporulation protein R
IHFHMFKI_01935 3.1e-244 ygxB M Conserved TM helix
IHFHMFKI_01936 1.6e-73 nsrR K Transcriptional regulator
IHFHMFKI_01937 3.4e-216 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
IHFHMFKI_01938 1.1e-53 yhdC S Protein of unknown function (DUF3889)
IHFHMFKI_01939 2.5e-39 yhdB S YhdB-like protein
IHFHMFKI_01940 7.4e-89 azr 1.7.1.6 S NADPH-dependent FMN reductase
IHFHMFKI_01941 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHFHMFKI_01942 7e-201 yhcY 2.7.13.3 T Histidine kinase
IHFHMFKI_01943 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
IHFHMFKI_01944 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IHFHMFKI_01945 1.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IHFHMFKI_01946 7.7e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
IHFHMFKI_01947 5.8e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
IHFHMFKI_01948 2.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IHFHMFKI_01949 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
IHFHMFKI_01950 4.9e-125 yhcW 5.4.2.6 S hydrolase
IHFHMFKI_01951 9.9e-68 yhcV S COG0517 FOG CBS domain
IHFHMFKI_01952 1.3e-69 yhcU S Family of unknown function (DUF5365)
IHFHMFKI_01953 4e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IHFHMFKI_01954 1.7e-105 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
IHFHMFKI_01955 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
IHFHMFKI_01956 8.4e-114 yhcQ M Spore coat protein
IHFHMFKI_01957 1.4e-159 yhcP
IHFHMFKI_01958 4.8e-83 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
IHFHMFKI_01959 1e-51 yhcM
IHFHMFKI_01960 1.1e-229 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IHFHMFKI_01961 2.5e-184 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
IHFHMFKI_01962 8.3e-143 metQ M Belongs to the nlpA lipoprotein family
IHFHMFKI_01963 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
IHFHMFKI_01964 8.2e-163 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IHFHMFKI_01965 7.7e-166 yhcH V ABC transporter, ATP-binding protein
IHFHMFKI_01966 1.3e-123 yhcG V ABC transporter, ATP-binding protein
IHFHMFKI_01967 2.8e-61 yhcF K Transcriptional regulator
IHFHMFKI_01968 1.6e-52
IHFHMFKI_01969 3.8e-55 yhcC
IHFHMFKI_01970 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
IHFHMFKI_01971 8.4e-285 yhcA EGP Major facilitator Superfamily
IHFHMFKI_01972 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
IHFHMFKI_01973 4.6e-74 yhbI K DNA-binding transcription factor activity
IHFHMFKI_01974 3.9e-215 yhbH S Belongs to the UPF0229 family
IHFHMFKI_01975 0.0 prkA T Ser protein kinase
IHFHMFKI_01977 5.5e-63 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
IHFHMFKI_01978 8.9e-61 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
IHFHMFKI_01979 1.1e-107 yhbD K Protein of unknown function (DUF4004)
IHFHMFKI_01980 2e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IHFHMFKI_01981 5.1e-173 yhbB S Putative amidase domain
IHFHMFKI_01982 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IHFHMFKI_01983 5.5e-107 yhzB S B3/4 domain
IHFHMFKI_01985 4.8e-23 K Transcriptional regulator
IHFHMFKI_01986 8.6e-81 ygaO
IHFHMFKI_01987 1.2e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHFHMFKI_01988 3.8e-215 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
IHFHMFKI_01989 1.3e-143 ssuC P ABC transporter (permease)
IHFHMFKI_01990 3.7e-166 ssuA M Sulfonate ABC transporter
IHFHMFKI_01991 6.1e-140 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
IHFHMFKI_01992 1.7e-181 S Amidohydrolase
IHFHMFKI_01993 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IHFHMFKI_01994 5.3e-133 oppF3 E Belongs to the ABC transporter superfamily
IHFHMFKI_01995 5.8e-135 oppD3 P Belongs to the ABC transporter superfamily
IHFHMFKI_01996 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
IHFHMFKI_01997 3.7e-147 appB P Binding-protein-dependent transport system inner membrane component
IHFHMFKI_01998 8.3e-230 oppA5 E PFAM extracellular solute-binding protein family 5
IHFHMFKI_02000 9e-264 ygaK C Berberine and berberine like
IHFHMFKI_02001 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IHFHMFKI_02002 2e-129 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
IHFHMFKI_02003 1.4e-18 C Na+/H+ antiporter family
IHFHMFKI_02007 1.6e-08
IHFHMFKI_02010 2.5e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
IHFHMFKI_02012 3.4e-47
IHFHMFKI_02018 1.5e-81 S dUTPase
IHFHMFKI_02020 1.3e-102 ydiP 2.1.1.37 H C-5 cytosine-specific DNA methylase
IHFHMFKI_02022 1.6e-27
IHFHMFKI_02024 2.1e-15 yqaO S Phage-like element PBSX protein XtrA
IHFHMFKI_02028 1.2e-28
IHFHMFKI_02029 3.7e-07
IHFHMFKI_02031 6.3e-42 dnaC L IstB-like ATP binding protein
IHFHMFKI_02032 2.4e-76 L dnaD_dom DnaD domain protein
IHFHMFKI_02034 4.8e-38 S Domain of unknown function (DUF771)
IHFHMFKI_02035 3.5e-12 S sequence-specific DNA binding
IHFHMFKI_02037 6.6e-21 K Helix-turn-helix XRE-family like proteins
IHFHMFKI_02039 2.6e-59
IHFHMFKI_02040 5.1e-129 S Phage integrase family
IHFHMFKI_02042 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IHFHMFKI_02043 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IHFHMFKI_02044 6.2e-142 est 3.1.1.1 S Carboxylesterase
IHFHMFKI_02045 4.8e-24 secG U Preprotein translocase subunit SecG
IHFHMFKI_02046 6e-35 yvzC K Transcriptional
IHFHMFKI_02047 1e-69 K transcriptional
IHFHMFKI_02048 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
IHFHMFKI_02049 8.8e-53 yodB K transcriptional
IHFHMFKI_02050 5.3e-259 T His Kinase A (phosphoacceptor) domain
IHFHMFKI_02051 1.4e-121 K Transcriptional regulatory protein, C terminal
IHFHMFKI_02052 7.7e-135 mutG S ABC-2 family transporter protein
IHFHMFKI_02053 4.9e-123 spaE S ABC-2 family transporter protein
IHFHMFKI_02054 1.2e-126 mutF V ABC transporter, ATP-binding protein
IHFHMFKI_02055 3.6e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IHFHMFKI_02056 1e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IHFHMFKI_02057 1e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IHFHMFKI_02058 3.3e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IHFHMFKI_02059 4.3e-76 yvbF K Belongs to the GbsR family
IHFHMFKI_02060 2.8e-109 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
IHFHMFKI_02061 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IHFHMFKI_02062 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
IHFHMFKI_02063 3.3e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
IHFHMFKI_02064 3.5e-97 yvbF K Belongs to the GbsR family
IHFHMFKI_02065 9.8e-104 yvbG U UPF0056 membrane protein
IHFHMFKI_02066 1.1e-119 exoY M Membrane
IHFHMFKI_02067 0.0 tcaA S response to antibiotic
IHFHMFKI_02068 2.5e-80 yvbK 3.1.3.25 K acetyltransferase
IHFHMFKI_02069 1.8e-210 EGP Major facilitator Superfamily
IHFHMFKI_02070 5.7e-177
IHFHMFKI_02071 7e-124 S GlcNAc-PI de-N-acetylase
IHFHMFKI_02072 2.1e-142 C WbqC-like protein family
IHFHMFKI_02073 1.1e-145 M Protein involved in cellulose biosynthesis
IHFHMFKI_02074 2.4e-226 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IHFHMFKI_02075 6.8e-170 5.1.3.2 M GDP-mannose 4,6 dehydratase
IHFHMFKI_02076 4.5e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IHFHMFKI_02077 8.9e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IHFHMFKI_02078 2.2e-235 ywaD 3.4.11.10, 3.4.11.6 S PA domain
IHFHMFKI_02079 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IHFHMFKI_02080 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
IHFHMFKI_02081 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IHFHMFKI_02082 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IHFHMFKI_02083 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IHFHMFKI_02084 2.6e-186 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IHFHMFKI_02086 7.4e-253 araE EGP Major facilitator Superfamily
IHFHMFKI_02087 3.2e-203 araR K transcriptional
IHFHMFKI_02088 2.4e-189 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHFHMFKI_02090 5.3e-156 yvbU K Transcriptional regulator
IHFHMFKI_02091 7.7e-158 yvbV EG EamA-like transporter family
IHFHMFKI_02092 1.1e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
IHFHMFKI_02094 5e-151 ybbH_1 K RpiR family transcriptional regulator
IHFHMFKI_02095 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
IHFHMFKI_02096 9.6e-210 gntP EG COG2610 H gluconate symporter and related permeases
IHFHMFKI_02097 7.4e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IHFHMFKI_02098 8e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
IHFHMFKI_02099 1.1e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
IHFHMFKI_02100 1.1e-217 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IHFHMFKI_02101 6.6e-120 yvfI K COG2186 Transcriptional regulators
IHFHMFKI_02102 3.8e-304 yvfH C L-lactate permease
IHFHMFKI_02103 7.2e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
IHFHMFKI_02104 2.7e-32 yvfG S YvfG protein
IHFHMFKI_02105 3.2e-186 yvfF GM Exopolysaccharide biosynthesis protein
IHFHMFKI_02106 4.1e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
IHFHMFKI_02107 4.2e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
IHFHMFKI_02108 6.3e-108 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IHFHMFKI_02109 1.6e-272 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IHFHMFKI_02110 6.8e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
IHFHMFKI_02111 2.9e-204 epsI GM pyruvyl transferase
IHFHMFKI_02112 1.1e-192 epsH GT2 S Glycosyltransferase like family 2
IHFHMFKI_02113 7.7e-205 epsG S EpsG family
IHFHMFKI_02114 2.3e-212 epsF GT4 M Glycosyl transferases group 1
IHFHMFKI_02115 5.8e-160 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IHFHMFKI_02116 1.1e-217 epsD GT4 M Glycosyl transferase 4-like
IHFHMFKI_02117 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
IHFHMFKI_02118 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
IHFHMFKI_02119 1.6e-118 ywqC M biosynthesis protein
IHFHMFKI_02120 1.9e-77 slr K transcriptional
IHFHMFKI_02121 2.7e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
IHFHMFKI_02123 3.7e-96 ywjB H RibD C-terminal domain
IHFHMFKI_02124 1.5e-112 yyaS S Membrane
IHFHMFKI_02125 3e-90 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHFHMFKI_02126 1.6e-93 padC Q Phenolic acid decarboxylase
IHFHMFKI_02127 4.3e-11 S Protein of unknown function (DUF1433)
IHFHMFKI_02128 2.2e-17 S Protein of unknown function (DUF1433)
IHFHMFKI_02129 9.8e-18 S Protein of unknown function (DUF1433)
IHFHMFKI_02130 4.9e-268 I Pfam Lipase (class 3)
IHFHMFKI_02131 2.6e-33
IHFHMFKI_02133 1.4e-291 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
IHFHMFKI_02134 1.5e-217 rafB P LacY proton/sugar symporter
IHFHMFKI_02135 3.3e-183 scrR K transcriptional
IHFHMFKI_02136 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IHFHMFKI_02137 3.3e-163 yraN K Transcriptional regulator
IHFHMFKI_02138 1.4e-209 yraM S PrpF protein
IHFHMFKI_02139 4.6e-247 EGP Sugar (and other) transporter
IHFHMFKI_02140 2.6e-10 yvdD 3.2.2.10 S Belongs to the LOG family
IHFHMFKI_02141 3.6e-105 yvdD 3.2.2.10 S Belongs to the LOG family
IHFHMFKI_02142 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
IHFHMFKI_02143 9.5e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
IHFHMFKI_02144 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
IHFHMFKI_02145 2.3e-181 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IHFHMFKI_02146 8.2e-79 M Ribonuclease
IHFHMFKI_02147 5.7e-143 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
IHFHMFKI_02148 4.7e-36 crh G Phosphocarrier protein Chr
IHFHMFKI_02149 5.3e-170 whiA K May be required for sporulation
IHFHMFKI_02150 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IHFHMFKI_02151 1.1e-166 rapZ S Displays ATPase and GTPase activities
IHFHMFKI_02152 6.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
IHFHMFKI_02153 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IHFHMFKI_02154 1.3e-124 usp CBM50 M protein conserved in bacteria
IHFHMFKI_02155 1.1e-275 S COG0457 FOG TPR repeat
IHFHMFKI_02156 2.3e-190 sasA T Histidine kinase
IHFHMFKI_02157 9.5e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_02158 2.7e-53
IHFHMFKI_02159 0.0 msbA2 3.6.3.44 V ABC transporter
IHFHMFKI_02160 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
IHFHMFKI_02161 4.9e-134 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IHFHMFKI_02162 6e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IHFHMFKI_02163 3.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IHFHMFKI_02164 2.6e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IHFHMFKI_02165 3e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IHFHMFKI_02166 1.1e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IHFHMFKI_02167 2.6e-206 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IHFHMFKI_02168 3.5e-137 yvpB NU protein conserved in bacteria
IHFHMFKI_02169 1.3e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
IHFHMFKI_02170 7e-113 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
IHFHMFKI_02171 7.6e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IHFHMFKI_02172 1.5e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IHFHMFKI_02173 1.7e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IHFHMFKI_02174 1.8e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IHFHMFKI_02175 2.3e-133 yvoA K transcriptional
IHFHMFKI_02176 4.4e-103 yxaF K Transcriptional regulator
IHFHMFKI_02177 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
IHFHMFKI_02178 3.3e-40 yvlD S Membrane
IHFHMFKI_02179 9.6e-26 pspB KT PspC domain
IHFHMFKI_02180 1.2e-165 yvlB S Putative adhesin
IHFHMFKI_02181 6.1e-49 yvlA
IHFHMFKI_02182 2.2e-32 yvkN
IHFHMFKI_02183 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IHFHMFKI_02184 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IHFHMFKI_02185 7.6e-33 csbA S protein conserved in bacteria
IHFHMFKI_02186 0.0 yvkC 2.7.9.2 GT Phosphotransferase
IHFHMFKI_02187 2e-109 yvkB K Transcriptional regulator
IHFHMFKI_02188 9.6e-226 yvkA EGP Major facilitator Superfamily
IHFHMFKI_02189 6.6e-177 S Psort location CytoplasmicMembrane, score
IHFHMFKI_02190 8.3e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHFHMFKI_02191 1.5e-55 swrA S Swarming motility protein
IHFHMFKI_02192 1.1e-251 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
IHFHMFKI_02193 1e-225 ywoF P Right handed beta helix region
IHFHMFKI_02194 1.2e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
IHFHMFKI_02195 2.3e-122 ftsE D cell division ATP-binding protein FtsE
IHFHMFKI_02196 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
IHFHMFKI_02197 3e-148 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
IHFHMFKI_02198 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IHFHMFKI_02199 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IHFHMFKI_02200 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IHFHMFKI_02201 6.8e-68
IHFHMFKI_02202 4.5e-10 fliT S bacterial-type flagellum organization
IHFHMFKI_02203 3e-66 fliS N flagellar protein FliS
IHFHMFKI_02204 8.9e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IHFHMFKI_02205 4.2e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IHFHMFKI_02206 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
IHFHMFKI_02207 7.2e-74 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
IHFHMFKI_02208 1.5e-79 yviE
IHFHMFKI_02209 2.3e-162 flgL N Belongs to the bacterial flagellin family
IHFHMFKI_02210 3.1e-273 flgK N flagellar hook-associated protein
IHFHMFKI_02211 3.4e-80 flgN NOU FlgN protein
IHFHMFKI_02212 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
IHFHMFKI_02213 4.1e-74 yvyF S flagellar protein
IHFHMFKI_02214 2.9e-76 comFC S Phosphoribosyl transferase domain
IHFHMFKI_02215 1.7e-42 comFB S Late competence development protein ComFB
IHFHMFKI_02216 1.3e-254 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IHFHMFKI_02217 1.9e-158 degV S protein conserved in bacteria
IHFHMFKI_02218 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHFHMFKI_02219 3.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
IHFHMFKI_02220 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
IHFHMFKI_02221 1e-165 yvhJ K Transcriptional regulator
IHFHMFKI_02222 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
IHFHMFKI_02223 3.3e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
IHFHMFKI_02224 8.9e-144 tuaG GT2 M Glycosyltransferase like family 2
IHFHMFKI_02225 7.3e-113 tuaF M protein involved in exopolysaccharide biosynthesis
IHFHMFKI_02226 8.9e-254 tuaE M Teichuronic acid biosynthesis protein
IHFHMFKI_02227 3.8e-246 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IHFHMFKI_02228 2.3e-223 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
IHFHMFKI_02229 3.5e-258 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IHFHMFKI_02230 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
IHFHMFKI_02231 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IHFHMFKI_02232 0.0 lytB 3.5.1.28 D Stage II sporulation protein
IHFHMFKI_02233 2.3e-48
IHFHMFKI_02234 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
IHFHMFKI_02235 4.5e-208 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IHFHMFKI_02236 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IHFHMFKI_02237 5.4e-281 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IHFHMFKI_02238 1.7e-151 tagG GM Transport permease protein
IHFHMFKI_02239 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IHFHMFKI_02240 7.8e-280 M Glycosyltransferase like family 2
IHFHMFKI_02241 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
IHFHMFKI_02242 3.8e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IHFHMFKI_02243 1.6e-216 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
IHFHMFKI_02244 9.7e-238 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IHFHMFKI_02245 7.7e-185 pmi 5.3.1.8 G mannose-6-phosphate isomerase
IHFHMFKI_02246 9.7e-264 gerBA EG Spore germination protein
IHFHMFKI_02247 7.8e-197 gerBB E Spore germination protein
IHFHMFKI_02248 2.2e-210 gerAC S Spore germination protein
IHFHMFKI_02249 1.5e-266 GT2,GT4 J Glycosyl transferase family 2
IHFHMFKI_02250 4.9e-249 ywtG EGP Major facilitator Superfamily
IHFHMFKI_02251 7.2e-178 ywtF K Transcriptional regulator
IHFHMFKI_02252 4.7e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
IHFHMFKI_02253 2.3e-32 yttA 2.7.13.3 S Pfam Transposase IS66
IHFHMFKI_02254 3.3e-236 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
IHFHMFKI_02255 1.3e-20 ywtC
IHFHMFKI_02256 9.8e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
IHFHMFKI_02257 2.3e-70 pgsC S biosynthesis protein
IHFHMFKI_02258 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
IHFHMFKI_02259 7.7e-184 gerKA EG Spore germination protein
IHFHMFKI_02260 8.2e-191 gerKB E Spore germination protein
IHFHMFKI_02261 7.4e-203 gerKC S Spore germination B3/ GerAC like, C-terminal
IHFHMFKI_02262 1.1e-178 rbsR K transcriptional
IHFHMFKI_02263 1.4e-156 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IHFHMFKI_02264 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IHFHMFKI_02265 1.9e-278 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
IHFHMFKI_02266 6.5e-155 rbsC G Belongs to the binding-protein-dependent transport system permease family
IHFHMFKI_02267 7.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
IHFHMFKI_02268 1.5e-89 batE T Sh3 type 3 domain protein
IHFHMFKI_02269 2e-94 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
IHFHMFKI_02270 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
IHFHMFKI_02271 2e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IHFHMFKI_02272 2.6e-166 alsR K LysR substrate binding domain
IHFHMFKI_02274 2.7e-236 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IHFHMFKI_02275 7.5e-126 ywrJ
IHFHMFKI_02276 2.8e-128 cotB
IHFHMFKI_02277 1.1e-211 cotH M Spore Coat
IHFHMFKI_02278 2e-09
IHFHMFKI_02279 1.3e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IHFHMFKI_02281 5e-298 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
IHFHMFKI_02282 2.5e-83 ywrC K Transcriptional regulator
IHFHMFKI_02283 9.5e-101 ywrB P Chromate transporter
IHFHMFKI_02284 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
IHFHMFKI_02286 3.3e-92 ywqN S NAD(P)H-dependent
IHFHMFKI_02287 3.1e-156 K Transcriptional regulator
IHFHMFKI_02288 1.1e-130 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
IHFHMFKI_02289 9.7e-14
IHFHMFKI_02291 3e-154 ywqJ S Pre-toxin TG
IHFHMFKI_02292 9e-41 S Protein of unknown function (DUF2004)
IHFHMFKI_02293 2.6e-49
IHFHMFKI_02294 7.4e-303 ywqJ S Pre-toxin TG
IHFHMFKI_02295 7.3e-37 ywqI S Family of unknown function (DUF5344)
IHFHMFKI_02296 1.4e-21 S Domain of unknown function (DUF5082)
IHFHMFKI_02297 5.3e-147 ywqG S Domain of unknown function (DUF1963)
IHFHMFKI_02298 1.3e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
IHFHMFKI_02299 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
IHFHMFKI_02300 1.6e-120 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
IHFHMFKI_02301 1.8e-109 ywqC M biosynthesis protein
IHFHMFKI_02302 1.3e-14
IHFHMFKI_02303 4.6e-307 ywqB S SWIM zinc finger
IHFHMFKI_02304 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
IHFHMFKI_02305 6.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
IHFHMFKI_02306 7.5e-138 glcR K DeoR C terminal sensor domain
IHFHMFKI_02307 3.7e-57 ssbB L Single-stranded DNA-binding protein
IHFHMFKI_02308 4e-62 ywpG
IHFHMFKI_02309 2.5e-68 ywpF S YwpF-like protein
IHFHMFKI_02310 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IHFHMFKI_02311 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IHFHMFKI_02312 5.2e-198 S aspartate phosphatase
IHFHMFKI_02313 7e-142 flhP N flagellar basal body
IHFHMFKI_02314 3.2e-128 flhO N flagellar basal body
IHFHMFKI_02315 2.7e-180 mbl D Rod shape-determining protein
IHFHMFKI_02316 1.8e-44 spoIIID K Stage III sporulation protein D
IHFHMFKI_02317 2.5e-71 ywoH K transcriptional
IHFHMFKI_02318 1.4e-212 ywoG EGP Major facilitator Superfamily
IHFHMFKI_02319 1.3e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
IHFHMFKI_02320 1e-243 ywoD EGP Major facilitator superfamily
IHFHMFKI_02321 4.8e-102 phzA Q Isochorismatase family
IHFHMFKI_02322 2.5e-228 amt P Ammonium transporter
IHFHMFKI_02323 2e-58 nrgB K Belongs to the P(II) protein family
IHFHMFKI_02324 3.9e-207 ftsW D Belongs to the SEDS family
IHFHMFKI_02325 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
IHFHMFKI_02326 5.6e-71 ywnJ S VanZ like family
IHFHMFKI_02327 1.4e-121 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
IHFHMFKI_02328 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
IHFHMFKI_02329 1.2e-10 ywnC S Family of unknown function (DUF5362)
IHFHMFKI_02330 4.2e-69 ywnF S Family of unknown function (DUF5392)
IHFHMFKI_02331 4.2e-275 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHFHMFKI_02332 1.2e-51 ywnC S Family of unknown function (DUF5362)
IHFHMFKI_02333 2e-120 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
IHFHMFKI_02334 6.1e-67 ywnA K Transcriptional regulator
IHFHMFKI_02335 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
IHFHMFKI_02336 1.9e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
IHFHMFKI_02337 1.2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
IHFHMFKI_02338 1.4e-10 csbD K CsbD-like
IHFHMFKI_02339 2.3e-81 ywmF S Peptidase M50
IHFHMFKI_02340 2.8e-93 S response regulator aspartate phosphatase
IHFHMFKI_02341 4.1e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IHFHMFKI_02342 2.4e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IHFHMFKI_02344 6.6e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
IHFHMFKI_02345 1.1e-113 ywmC S protein containing a von Willebrand factor type A (vWA) domain
IHFHMFKI_02346 4e-179 spoIID D Stage II sporulation protein D
IHFHMFKI_02347 1.1e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHFHMFKI_02348 2.2e-134 ywmB S TATA-box binding
IHFHMFKI_02349 4.8e-32 ywzB S membrane
IHFHMFKI_02350 8.7e-89 ywmA
IHFHMFKI_02351 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IHFHMFKI_02352 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IHFHMFKI_02353 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IHFHMFKI_02354 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IHFHMFKI_02355 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHFHMFKI_02356 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IHFHMFKI_02357 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IHFHMFKI_02358 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
IHFHMFKI_02359 2.1e-61 atpI S ATP synthase
IHFHMFKI_02360 2.3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IHFHMFKI_02361 5.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IHFHMFKI_02362 5e-96 ywlG S Belongs to the UPF0340 family
IHFHMFKI_02363 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
IHFHMFKI_02364 4.3e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHFHMFKI_02365 1.3e-83 mntP P Probably functions as a manganese efflux pump
IHFHMFKI_02366 3.3e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IHFHMFKI_02367 8.8e-75 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
IHFHMFKI_02368 8.9e-119 spoIIR S stage II sporulation protein R
IHFHMFKI_02369 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
IHFHMFKI_02371 1.1e-153 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IHFHMFKI_02372 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IHFHMFKI_02373 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IHFHMFKI_02374 2.2e-94 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
IHFHMFKI_02375 6.8e-157 ywkB S Membrane transport protein
IHFHMFKI_02376 0.0 sfcA 1.1.1.38 C malic enzyme
IHFHMFKI_02377 8.6e-102 tdk 2.7.1.21 F thymidine kinase
IHFHMFKI_02378 1.1e-32 rpmE J Binds the 23S rRNA
IHFHMFKI_02379 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IHFHMFKI_02380 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
IHFHMFKI_02381 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IHFHMFKI_02382 1.9e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IHFHMFKI_02383 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
IHFHMFKI_02384 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
IHFHMFKI_02385 2.4e-92 ywjG S Domain of unknown function (DUF2529)
IHFHMFKI_02386 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IHFHMFKI_02387 2.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IHFHMFKI_02388 0.0 fadF C COG0247 Fe-S oxidoreductase
IHFHMFKI_02389 2.3e-218 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
IHFHMFKI_02390 2.9e-179 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
IHFHMFKI_02391 4.2e-43 ywjC
IHFHMFKI_02392 1e-301 ywjA V ABC transporter
IHFHMFKI_02393 1.3e-295 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IHFHMFKI_02394 3.4e-104 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHFHMFKI_02395 7.2e-121 narI 1.7.5.1 C nitrate reductase, gamma
IHFHMFKI_02396 4.8e-94 narJ 1.7.5.1 C nitrate reductase
IHFHMFKI_02397 4.8e-295 narH 1.7.5.1 C Nitrate reductase, beta
IHFHMFKI_02398 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IHFHMFKI_02399 1e-84 arfM T cyclic nucleotide binding
IHFHMFKI_02400 2.8e-139 ywiC S YwiC-like protein
IHFHMFKI_02401 5e-128 fnr K helix_turn_helix, cAMP Regulatory protein
IHFHMFKI_02402 5.4e-212 narK P COG2223 Nitrate nitrite transporter
IHFHMFKI_02403 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IHFHMFKI_02404 2.9e-43 ywiB S protein conserved in bacteria
IHFHMFKI_02405 4.4e-78 S aspartate phosphatase
IHFHMFKI_02407 3.8e-57 speB 3.5.3.11 E Belongs to the arginase family
IHFHMFKI_02409 2.3e-25 norM_1 V drug transmembrane transporter activity
IHFHMFKI_02410 3.2e-38 C Nitroreductase family
IHFHMFKI_02411 2.2e-42 C coenzyme F420-1:gamma-L-glutamate ligase activity
IHFHMFKI_02413 2.9e-227 argS 6.1.1.19 J Arginyl-tRNA synthetase
IHFHMFKI_02414 7.8e-168 speB 3.5.3.11 E Belongs to the arginase family
IHFHMFKI_02415 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IHFHMFKI_02416 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IHFHMFKI_02417 1.6e-81
IHFHMFKI_02418 8.4e-93 ywhD S YwhD family
IHFHMFKI_02419 1.2e-117 ywhC S Peptidase family M50
IHFHMFKI_02420 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
IHFHMFKI_02421 4.9e-67 ywhA K Transcriptional regulator
IHFHMFKI_02422 1.9e-245 yhdG_1 E C-terminus of AA_permease
IHFHMFKI_02423 4.6e-88 ywgA 2.1.1.72, 3.1.21.3
IHFHMFKI_02424 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
IHFHMFKI_02425 6.9e-36 ywzC S Belongs to the UPF0741 family
IHFHMFKI_02426 6.6e-110 rsfA_1
IHFHMFKI_02427 9.7e-52 padR K PadR family transcriptional regulator
IHFHMFKI_02428 3.4e-92 S membrane
IHFHMFKI_02429 2.1e-40 V ABC transporter, ATP-binding protein
IHFHMFKI_02430 4.4e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
IHFHMFKI_02431 3e-162 cysL K Transcriptional regulator
IHFHMFKI_02432 4e-157 MA20_14895 S Conserved hypothetical protein 698
IHFHMFKI_02433 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
IHFHMFKI_02434 3.3e-146 ywfI C May function as heme-dependent peroxidase
IHFHMFKI_02435 5.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
IHFHMFKI_02436 1.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
IHFHMFKI_02437 4e-207 bacE EGP Major facilitator Superfamily
IHFHMFKI_02438 1.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
IHFHMFKI_02439 8.7e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_02440 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
IHFHMFKI_02441 3.9e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
IHFHMFKI_02442 7.8e-222 ywfA EGP Major facilitator Superfamily
IHFHMFKI_02443 8.4e-205 tcaB EGP Major facilitator Superfamily
IHFHMFKI_02444 4.5e-258 lysP E amino acid
IHFHMFKI_02445 0.0 rocB E arginine degradation protein
IHFHMFKI_02446 1e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IHFHMFKI_02447 1.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
IHFHMFKI_02448 1.9e-59
IHFHMFKI_02449 3e-86 spsL 5.1.3.13 M Spore Coat
IHFHMFKI_02450 4e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
IHFHMFKI_02451 7.9e-182 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
IHFHMFKI_02452 1.3e-136 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IHFHMFKI_02453 3.3e-178 spsG M Spore Coat
IHFHMFKI_02454 2.6e-132 spsF M Spore Coat
IHFHMFKI_02455 3.8e-215 spsE 2.5.1.56 M acid synthase
IHFHMFKI_02456 1.2e-155 spsD 2.3.1.210 K Spore Coat
IHFHMFKI_02457 4e-220 spsC E Belongs to the DegT DnrJ EryC1 family
IHFHMFKI_02458 9.1e-275 spsB M Capsule polysaccharide biosynthesis protein
IHFHMFKI_02459 1.7e-142 spsA M Spore Coat
IHFHMFKI_02460 4e-61 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
IHFHMFKI_02461 4.2e-46 ywdK S small membrane protein
IHFHMFKI_02462 5.4e-229 ywdJ F Xanthine uracil
IHFHMFKI_02463 4.7e-41 ywdI S Family of unknown function (DUF5327)
IHFHMFKI_02464 3.7e-133 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IHFHMFKI_02465 1.8e-150 ywdF GT2,GT4 S Glycosyltransferase like family 2
IHFHMFKI_02467 1.3e-87 ywdD
IHFHMFKI_02468 6.3e-57 pex K Transcriptional regulator PadR-like family
IHFHMFKI_02469 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IHFHMFKI_02470 7.4e-20 ywdA
IHFHMFKI_02471 6.4e-284 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
IHFHMFKI_02472 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IHFHMFKI_02473 3.7e-151 sacT K transcriptional antiterminator
IHFHMFKI_02475 0.0 vpr O Belongs to the peptidase S8 family
IHFHMFKI_02476 8.9e-184 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHFHMFKI_02477 2e-135 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
IHFHMFKI_02478 8e-208 rodA D Belongs to the SEDS family
IHFHMFKI_02479 1.7e-76 ysnE K acetyltransferase
IHFHMFKI_02480 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
IHFHMFKI_02481 2.4e-62 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IHFHMFKI_02482 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
IHFHMFKI_02483 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IHFHMFKI_02484 4.1e-178 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
IHFHMFKI_02485 8.4e-27 ywzA S membrane
IHFHMFKI_02486 1.2e-293 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IHFHMFKI_02487 5.1e-61 gtcA S GtrA-like protein
IHFHMFKI_02488 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
IHFHMFKI_02490 7.3e-129 H Methionine biosynthesis protein MetW
IHFHMFKI_02491 1.2e-131 S Streptomycin biosynthesis protein StrF
IHFHMFKI_02492 3e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
IHFHMFKI_02493 1.4e-242 ywbN P Dyp-type peroxidase family protein
IHFHMFKI_02494 1.1e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IHFHMFKI_02495 4.8e-135 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IHFHMFKI_02496 8.2e-152 ywbI K Transcriptional regulator
IHFHMFKI_02497 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
IHFHMFKI_02498 1.3e-109 ywbG M effector of murein hydrolase
IHFHMFKI_02499 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
IHFHMFKI_02500 1.1e-136 mta K transcriptional
IHFHMFKI_02501 1e-223 ywbD 2.1.1.191 J Methyltransferase
IHFHMFKI_02502 7.6e-67 ywbC 4.4.1.5 E glyoxalase
IHFHMFKI_02503 5.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHFHMFKI_02504 5.4e-261 epr 3.4.21.62 O Belongs to the peptidase S8 family
IHFHMFKI_02505 4.1e-161 gspA M General stress
IHFHMFKI_02506 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
IHFHMFKI_02507 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
IHFHMFKI_02508 6.1e-12 S D-Ala-teichoic acid biosynthesis protein
IHFHMFKI_02509 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_02510 4.8e-229 dltB M membrane protein involved in D-alanine export
IHFHMFKI_02511 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_02512 3.8e-226 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IHFHMFKI_02513 1.9e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IHFHMFKI_02514 1e-251 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IHFHMFKI_02515 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
IHFHMFKI_02516 7.4e-250 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHFHMFKI_02517 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
IHFHMFKI_02518 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
IHFHMFKI_02519 2.3e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IHFHMFKI_02520 2.8e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_02521 7.9e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_02522 1.5e-166 cbrA3 P Periplasmic binding protein
IHFHMFKI_02523 1.7e-57 arsR K transcriptional
IHFHMFKI_02524 2.5e-226 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IHFHMFKI_02525 5.8e-49 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
IHFHMFKI_02526 2.3e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
IHFHMFKI_02527 5.4e-229 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IHFHMFKI_02528 2.4e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IHFHMFKI_02529 1.2e-163 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
IHFHMFKI_02530 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
IHFHMFKI_02531 2.7e-210 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
IHFHMFKI_02532 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
IHFHMFKI_02533 1.4e-194 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IHFHMFKI_02534 7.9e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
IHFHMFKI_02535 4.7e-154 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IHFHMFKI_02536 1.3e-291 cydD V ATP-binding protein
IHFHMFKI_02537 0.0 cydD V ATP-binding
IHFHMFKI_02538 2.5e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
IHFHMFKI_02539 5e-265 cydA 1.10.3.14 C oxidase, subunit
IHFHMFKI_02540 5e-214 cimH C COG3493 Na citrate symporter
IHFHMFKI_02541 4.3e-155 yxkH G Polysaccharide deacetylase
IHFHMFKI_02542 2.6e-205 msmK P Belongs to the ABC transporter superfamily
IHFHMFKI_02543 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
IHFHMFKI_02544 3.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IHFHMFKI_02545 3.8e-87 yxkC S Domain of unknown function (DUF4352)
IHFHMFKI_02546 2.8e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IHFHMFKI_02547 1.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IHFHMFKI_02550 2e-85 yxjI S LURP-one-related
IHFHMFKI_02551 1.8e-217 yxjG 2.1.1.14 E Methionine synthase
IHFHMFKI_02552 6.5e-154 rlmA 2.1.1.187 Q Methyltransferase domain
IHFHMFKI_02553 2.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHFHMFKI_02554 1.8e-71 T Domain of unknown function (DUF4163)
IHFHMFKI_02555 1.5e-49 yxiS
IHFHMFKI_02556 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
IHFHMFKI_02557 3.1e-221 citH C Citrate transporter
IHFHMFKI_02558 2e-140 exoK GH16 M licheninase activity
IHFHMFKI_02560 1e-106 licT K transcriptional antiterminator
IHFHMFKI_02561 5.1e-221 yxiO S COG2270 Permeases of the major facilitator superfamily
IHFHMFKI_02562 6.9e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
IHFHMFKI_02565 1.2e-61 S SMI1-KNR4 cell-wall
IHFHMFKI_02566 1.6e-48 yxiI S Protein of unknown function (DUF2716)
IHFHMFKI_02567 1.3e-20
IHFHMFKI_02568 1.3e-13 S YxiJ-like protein
IHFHMFKI_02569 2.7e-109
IHFHMFKI_02570 4.6e-79
IHFHMFKI_02571 8.6e-69 yxiG
IHFHMFKI_02572 1.2e-44 yxxG
IHFHMFKI_02573 1.2e-199 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
IHFHMFKI_02574 4.7e-147 yxxF EG EamA-like transporter family
IHFHMFKI_02575 1.8e-72 yxiE T Belongs to the universal stress protein A family
IHFHMFKI_02578 2.5e-64 K Transcriptional regulator
IHFHMFKI_02580 9e-25
IHFHMFKI_02581 7e-102 L Replication protein
IHFHMFKI_02582 1.1e-13 S Domain of unknown function (DUF5082)
IHFHMFKI_02583 5.1e-45 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
IHFHMFKI_02584 1.9e-182 2.1.1.37 H C-5 cytosine-specific DNA methylase
IHFHMFKI_02585 2e-180 L AlwI restriction endonuclease
IHFHMFKI_02586 8.4e-09
IHFHMFKI_02587 5.3e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
IHFHMFKI_02588 7.7e-79 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
IHFHMFKI_02589 1.8e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
IHFHMFKI_02590 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IHFHMFKI_02591 1.4e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
IHFHMFKI_02592 4.7e-174 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
IHFHMFKI_02593 4.4e-253 lysP E amino acid
IHFHMFKI_02594 2.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
IHFHMFKI_02595 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHFHMFKI_02596 3.6e-112 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IHFHMFKI_02597 9.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
IHFHMFKI_02598 2.6e-149 yidA S hydrolases of the HAD superfamily
IHFHMFKI_02602 8.4e-23 yxeD
IHFHMFKI_02603 1.3e-34
IHFHMFKI_02604 4.1e-178 fhuD P Periplasmic binding protein
IHFHMFKI_02605 1.3e-57 yxeA S Protein of unknown function (DUF1093)
IHFHMFKI_02606 0.0 yxdM V ABC transporter (permease)
IHFHMFKI_02607 3.6e-140 yxdL V ABC transporter, ATP-binding protein
IHFHMFKI_02608 3.5e-177 T PhoQ Sensor
IHFHMFKI_02609 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_02610 1.8e-156 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
IHFHMFKI_02611 6.6e-148 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
IHFHMFKI_02612 3.3e-166 iolH G Xylose isomerase-like TIM barrel
IHFHMFKI_02613 2.6e-194 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
IHFHMFKI_02614 6.7e-232 iolF EGP Major facilitator Superfamily
IHFHMFKI_02615 3.4e-174 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
IHFHMFKI_02616 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
IHFHMFKI_02617 2.7e-180 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
IHFHMFKI_02618 1.6e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
IHFHMFKI_02619 4.8e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IHFHMFKI_02620 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
IHFHMFKI_02621 1.2e-174 iolS C Aldo keto reductase
IHFHMFKI_02622 1.9e-245 csbC EGP Major facilitator Superfamily
IHFHMFKI_02623 0.0 htpG O Molecular chaperone. Has ATPase activity
IHFHMFKI_02625 6.9e-150 IQ Enoyl-(Acyl carrier protein) reductase
IHFHMFKI_02626 1e-102 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHFHMFKI_02627 4.5e-200 desK 2.7.13.3 T Histidine kinase
IHFHMFKI_02628 9.6e-197 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
IHFHMFKI_02629 6.2e-213 yxbF K Bacterial regulatory proteins, tetR family
IHFHMFKI_02630 3.6e-249 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
IHFHMFKI_02631 1.1e-141 S PQQ-like domain
IHFHMFKI_02632 1.7e-64 S Family of unknown function (DUF5391)
IHFHMFKI_02633 3e-50 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
IHFHMFKI_02634 1.3e-199 EGP Major facilitator Superfamily
IHFHMFKI_02635 3.8e-73 yxaI S membrane protein domain
IHFHMFKI_02636 2.2e-125 E Ring-cleavage extradiol dioxygenase
IHFHMFKI_02637 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
IHFHMFKI_02638 2.3e-287 ahpF O Alkyl hydroperoxide reductase
IHFHMFKI_02639 1.6e-244 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
IHFHMFKI_02640 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
IHFHMFKI_02641 1.3e-81 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
IHFHMFKI_02642 2.6e-152 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
IHFHMFKI_02643 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
IHFHMFKI_02644 7.4e-88 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
IHFHMFKI_02645 1.8e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
IHFHMFKI_02646 1.5e-178 S Fusaric acid resistance protein-like
IHFHMFKI_02647 1.3e-23 V Domain of unknown function (DUF3883)
IHFHMFKI_02649 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IHFHMFKI_02650 7.9e-08 S YyzF-like protein
IHFHMFKI_02652 3e-215 yycP
IHFHMFKI_02653 2.7e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
IHFHMFKI_02654 3.1e-181 C oxidoreductases (related to aryl-alcohol dehydrogenases)
IHFHMFKI_02655 1.4e-86 yycN 2.3.1.128 K Acetyltransferase
IHFHMFKI_02657 2.2e-199 S Histidine kinase
IHFHMFKI_02658 4e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
IHFHMFKI_02659 3.8e-257 rocE E amino acid
IHFHMFKI_02660 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
IHFHMFKI_02661 7.7e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
IHFHMFKI_02662 5.9e-145 1.14.11.27 P peptidyl-arginine hydroxylation
IHFHMFKI_02663 1.3e-304 S ABC transporter
IHFHMFKI_02664 4.5e-195 S Major Facilitator Superfamily
IHFHMFKI_02665 1e-256
IHFHMFKI_02666 7.1e-189 2.7.7.73, 2.7.7.80 H ThiF family
IHFHMFKI_02667 5.6e-248 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
IHFHMFKI_02668 2.8e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_02669 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHFHMFKI_02670 3.9e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
IHFHMFKI_02671 1.1e-150 yycI S protein conserved in bacteria
IHFHMFKI_02672 2.5e-261 yycH S protein conserved in bacteria
IHFHMFKI_02673 0.0 vicK 2.7.13.3 T Histidine kinase
IHFHMFKI_02674 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_02679 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IHFHMFKI_02680 4.2e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IHFHMFKI_02681 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IHFHMFKI_02682 5.7e-26 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
IHFHMFKI_02684 4.6e-17 yycC K YycC-like protein
IHFHMFKI_02685 2.2e-235 M Glycosyltransferase Family 4
IHFHMFKI_02686 2.4e-203 S Ecdysteroid kinase
IHFHMFKI_02687 2.5e-233 S Carbamoyl-phosphate synthase L chain, ATP binding domain
IHFHMFKI_02688 1.6e-241 M Glycosyltransferase Family 4
IHFHMFKI_02689 1.1e-121 S GlcNAc-PI de-N-acetylase
IHFHMFKI_02690 8.2e-102 KLT COG0515 Serine threonine protein kinase
IHFHMFKI_02691 4.9e-73 rplI J binds to the 23S rRNA
IHFHMFKI_02692 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IHFHMFKI_02693 1.2e-158 yybS S membrane
IHFHMFKI_02695 2.1e-83 cotF M Spore coat protein
IHFHMFKI_02696 8.2e-66 ydeP3 K Transcriptional regulator
IHFHMFKI_02697 5e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
IHFHMFKI_02698 5.3e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IHFHMFKI_02699 2.9e-273 sacB 2.4.1.10 GH68 M levansucrase activity
IHFHMFKI_02700 4.3e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
IHFHMFKI_02701 2.2e-114 K FCD domain
IHFHMFKI_02702 1.8e-71 dinB S PFAM DinB family protein
IHFHMFKI_02703 3.2e-159 G Major Facilitator Superfamily
IHFHMFKI_02704 2.2e-55 ypaA S Protein of unknown function (DUF1304)
IHFHMFKI_02705 5.6e-115 drgA C nitroreductase
IHFHMFKI_02706 4.1e-69 ydgJ K Winged helix DNA-binding domain
IHFHMFKI_02707 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
IHFHMFKI_02708 1.6e-76 yybA 2.3.1.57 K transcriptional
IHFHMFKI_02709 1.4e-41 yjcF S Acetyltransferase (GNAT) domain
IHFHMFKI_02711 2.4e-161 eaeH M Domain of Unknown Function (DUF1259)
IHFHMFKI_02712 8.8e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
IHFHMFKI_02713 8.6e-162 K Transcriptional regulator
IHFHMFKI_02714 3.9e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
IHFHMFKI_02715 9.4e-251 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IHFHMFKI_02716 2.1e-131 ydfC EG EamA-like transporter family
IHFHMFKI_02717 1.1e-99 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IHFHMFKI_02718 2.8e-77 K Transcriptional regulator
IHFHMFKI_02719 7.6e-14 yvaO K Transcriptional
IHFHMFKI_02720 2.7e-40 qacC U Small Multidrug Resistance protein
IHFHMFKI_02721 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
IHFHMFKI_02722 7.3e-161 yyaK S CAAX protease self-immunity
IHFHMFKI_02723 5.8e-247 ydjK G Sugar (and other) transporter
IHFHMFKI_02724 9.9e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IHFHMFKI_02725 5.2e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
IHFHMFKI_02726 6e-140 xth 3.1.11.2 L exodeoxyribonuclease III
IHFHMFKI_02727 2.7e-97 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IHFHMFKI_02728 4.8e-105 adaA 3.2.2.21 K Transcriptional regulator
IHFHMFKI_02729 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IHFHMFKI_02730 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IHFHMFKI_02731 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
IHFHMFKI_02732 2.6e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IHFHMFKI_02733 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IHFHMFKI_02734 2.3e-33 yyzM S protein conserved in bacteria
IHFHMFKI_02735 2.4e-176 yyaD S Membrane
IHFHMFKI_02736 6.2e-111 yyaC S Sporulation protein YyaC
IHFHMFKI_02737 7.9e-149 spo0J K Belongs to the ParB family
IHFHMFKI_02738 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
IHFHMFKI_02739 3.8e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
IHFHMFKI_02740 1.6e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
IHFHMFKI_02741 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IHFHMFKI_02742 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IHFHMFKI_02743 1.3e-108 jag S single-stranded nucleic acid binding R3H
IHFHMFKI_02744 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IHFHMFKI_02745 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IHFHMFKI_02746 2.3e-248 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IHFHMFKI_02748 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IHFHMFKI_02749 2.4e-33 yaaA S S4 domain
IHFHMFKI_02750 1.6e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IHFHMFKI_02751 8.1e-38 yaaB S Domain of unknown function (DUF370)
IHFHMFKI_02752 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHFHMFKI_02753 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IHFHMFKI_02754 2.4e-286 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_02755 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
IHFHMFKI_02756 3.4e-140 srfAD Q thioesterase
IHFHMFKI_02757 6.7e-248 bamJ E Aminotransferase class I and II
IHFHMFKI_02758 2.2e-130 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IHFHMFKI_02759 1.7e-108 yczE S membrane
IHFHMFKI_02760 1.2e-132 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IHFHMFKI_02761 6.3e-120 tcyB P COG0765 ABC-type amino acid transport system, permease component
IHFHMFKI_02762 1.2e-143 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IHFHMFKI_02763 3.9e-159 bsdA K LysR substrate binding domain
IHFHMFKI_02764 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IHFHMFKI_02765 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
IHFHMFKI_02766 1.7e-37 bsdD 4.1.1.61 S response to toxic substance
IHFHMFKI_02767 1.3e-76 yclD
IHFHMFKI_02768 1.2e-269 dtpT E amino acid peptide transporter
IHFHMFKI_02769 1.2e-276 yclG M Pectate lyase superfamily protein
IHFHMFKI_02771 7.8e-294 gerKA EG Spore germination protein
IHFHMFKI_02772 5.2e-234 gerKC S spore germination
IHFHMFKI_02773 2.5e-195 gerKB F Spore germination protein
IHFHMFKI_02774 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHFHMFKI_02775 1.1e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IHFHMFKI_02776 1.3e-140 yxeM M Belongs to the bacterial solute-binding protein 3 family
IHFHMFKI_02777 4.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
IHFHMFKI_02778 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
IHFHMFKI_02779 6.4e-218 yxeP 3.5.1.47 E hydrolase activity
IHFHMFKI_02780 1.9e-250 yxeQ S MmgE/PrpD family
IHFHMFKI_02781 1.6e-120 yclH P ABC transporter
IHFHMFKI_02782 1e-228 yclI V ABC transporter (permease) YclI
IHFHMFKI_02783 6.8e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_02784 4.1e-259 T PhoQ Sensor
IHFHMFKI_02785 9.5e-81 S aspartate phosphatase
IHFHMFKI_02787 4.5e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
IHFHMFKI_02788 1.2e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_02789 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_02790 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
IHFHMFKI_02791 6e-174 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
IHFHMFKI_02792 1.2e-245 ycnB EGP Major facilitator Superfamily
IHFHMFKI_02793 6.7e-151 ycnC K Transcriptional regulator
IHFHMFKI_02794 2e-135 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
IHFHMFKI_02795 1e-44 ycnE S Monooxygenase
IHFHMFKI_02796 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
IHFHMFKI_02797 6.7e-262 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IHFHMFKI_02798 2.1e-217 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IHFHMFKI_02799 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IHFHMFKI_02800 3.6e-149 glcU U Glucose uptake
IHFHMFKI_02801 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_02802 3.9e-97 ycnI S protein conserved in bacteria
IHFHMFKI_02803 2e-297 ycnJ P protein, homolog of Cu resistance protein CopC
IHFHMFKI_02804 5.6e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
IHFHMFKI_02805 1.6e-55
IHFHMFKI_02806 7.9e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
IHFHMFKI_02807 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
IHFHMFKI_02808 1.3e-204 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
IHFHMFKI_02809 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IHFHMFKI_02811 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
IHFHMFKI_02812 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
IHFHMFKI_02813 4.4e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
IHFHMFKI_02814 2.1e-148 ycsI S Belongs to the D-glutamate cyclase family
IHFHMFKI_02815 4.3e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
IHFHMFKI_02816 1.2e-188 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
IHFHMFKI_02817 1.3e-129 kipR K Transcriptional regulator
IHFHMFKI_02818 1e-116 ycsK E anatomical structure formation involved in morphogenesis
IHFHMFKI_02820 5.1e-56 yczJ S biosynthesis
IHFHMFKI_02821 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
IHFHMFKI_02822 3.7e-173 ydhF S Oxidoreductase
IHFHMFKI_02823 0.0 mtlR K transcriptional regulator, MtlR
IHFHMFKI_02824 5.5e-286 ydaB IQ acyl-CoA ligase
IHFHMFKI_02825 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_02826 1.1e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
IHFHMFKI_02827 5.5e-115 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
IHFHMFKI_02828 1.4e-77 ydaG 1.4.3.5 S general stress protein
IHFHMFKI_02829 1.2e-138 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
IHFHMFKI_02830 1.3e-47 ydzA EGP Major facilitator Superfamily
IHFHMFKI_02831 4.3e-74 lrpC K Transcriptional regulator
IHFHMFKI_02832 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IHFHMFKI_02833 2.8e-199 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
IHFHMFKI_02834 2.5e-147 ydaK T Diguanylate cyclase, GGDEF domain
IHFHMFKI_02835 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
IHFHMFKI_02836 7.2e-231 ydaM M Glycosyl transferase family group 2
IHFHMFKI_02837 0.0 ydaN S Bacterial cellulose synthase subunit
IHFHMFKI_02838 0.0 ydaO E amino acid
IHFHMFKI_02839 4.5e-71 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
IHFHMFKI_02840 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IHFHMFKI_02841 1.4e-12
IHFHMFKI_02843 3.1e-77
IHFHMFKI_02844 8.2e-97
IHFHMFKI_02845 1.8e-38
IHFHMFKI_02846 2.7e-225 mntH P H( )-stimulated, divalent metal cation uptake system
IHFHMFKI_02848 6.5e-34 ydaT
IHFHMFKI_02849 3.7e-72 yvaD S Family of unknown function (DUF5360)
IHFHMFKI_02850 4.6e-53 yvaE P Small Multidrug Resistance protein
IHFHMFKI_02851 1.7e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
IHFHMFKI_02853 3.4e-58 ydbB G Cupin domain
IHFHMFKI_02854 8.5e-60 ydbC S Domain of unknown function (DUF4937
IHFHMFKI_02855 1.2e-154 ydbD P Catalase
IHFHMFKI_02856 1.9e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
IHFHMFKI_02857 3.6e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IHFHMFKI_02858 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
IHFHMFKI_02859 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IHFHMFKI_02860 4e-158 ydbI S AI-2E family transporter
IHFHMFKI_02861 2.3e-170 ydbJ V ABC transporter, ATP-binding protein
IHFHMFKI_02862 2.2e-129 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
IHFHMFKI_02863 4.6e-52 ydbL
IHFHMFKI_02864 3e-204 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
IHFHMFKI_02865 1.5e-10 S Fur-regulated basic protein B
IHFHMFKI_02866 5.8e-09 S Fur-regulated basic protein A
IHFHMFKI_02867 3.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHFHMFKI_02868 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IHFHMFKI_02869 9.3e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IHFHMFKI_02870 1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IHFHMFKI_02871 1.4e-246 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IHFHMFKI_02872 1.3e-60 ydbS S Bacterial PH domain
IHFHMFKI_02873 2.9e-260 ydbT S Membrane
IHFHMFKI_02874 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
IHFHMFKI_02875 6.8e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IHFHMFKI_02876 5.8e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
IHFHMFKI_02877 2.6e-219 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IHFHMFKI_02878 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
IHFHMFKI_02879 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
IHFHMFKI_02880 6.7e-145 rsbR T Positive regulator of sigma-B
IHFHMFKI_02881 1.8e-57 rsbS T antagonist
IHFHMFKI_02882 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
IHFHMFKI_02883 1.7e-187 rsbU 3.1.3.3 KT phosphatase
IHFHMFKI_02884 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
IHFHMFKI_02885 1e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
IHFHMFKI_02886 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IHFHMFKI_02887 1.8e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
IHFHMFKI_02888 0.0 yhgF K COG2183 Transcriptional accessory protein
IHFHMFKI_02889 1.7e-14
IHFHMFKI_02890 5.6e-58 ydcK S Belongs to the SprT family
IHFHMFKI_02898 1.1e-95 ywrO S Flavodoxin-like fold
IHFHMFKI_02899 6.8e-150 S Serine aminopeptidase, S33
IHFHMFKI_02900 5.7e-229 proP EGP Transporter
IHFHMFKI_02901 3.8e-136 I esterase
IHFHMFKI_02902 1.3e-46 ohrB O OsmC-like protein
IHFHMFKI_02903 1.4e-48 ohrR K Transcriptional regulator
IHFHMFKI_02904 1.6e-71 ywnA K Transcriptional regulator
IHFHMFKI_02905 5.4e-110 ywnB S NAD(P)H-binding
IHFHMFKI_02906 1.4e-30 cspL K Cold shock
IHFHMFKI_02907 6.8e-78 carD K Transcription factor
IHFHMFKI_02908 9.2e-40 yrkD S protein conserved in bacteria
IHFHMFKI_02909 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
IHFHMFKI_02910 2.2e-17 P Rhodanese Homology Domain
IHFHMFKI_02911 2.9e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
IHFHMFKI_02912 7.6e-200 yrkH P Rhodanese Homology Domain
IHFHMFKI_02913 1.2e-35 yrkI O Belongs to the sulfur carrier protein TusA family
IHFHMFKI_02914 1.5e-117 yrkJ S membrane transporter protein
IHFHMFKI_02915 5.8e-118 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IHFHMFKI_02916 1.1e-101 S Protein of unknown function (DUF2812)
IHFHMFKI_02917 2.4e-50 K Transcriptional regulator PadR-like family
IHFHMFKI_02918 5.2e-181 S Patatin-like phospholipase
IHFHMFKI_02919 2.7e-82 S DinB superfamily
IHFHMFKI_02920 4.7e-115 ygeX 4.3.1.15, 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
IHFHMFKI_02921 4.5e-67 K COG1802 Transcriptional regulators
IHFHMFKI_02922 1.7e-39 yabJ 3.5.99.10 J Endoribonuclease L-PSP
IHFHMFKI_02923 2.2e-142 sdaC E Serine transporter
IHFHMFKI_02924 5.3e-164 E Peptidase dimerisation domain
IHFHMFKI_02925 7.6e-126 rhaS5 K helix_turn_helix, arabinose operon control protein
IHFHMFKI_02926 3.2e-175 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IHFHMFKI_02927 6.5e-233 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
IHFHMFKI_02928 2.6e-191 ydeG EGP Major facilitator superfamily
IHFHMFKI_02929 3.5e-28 3.6.1.55 F Belongs to the Nudix hydrolase family
IHFHMFKI_02932 4.3e-266 ygaK C COG0277 FAD FMN-containing dehydrogenases
IHFHMFKI_02933 1.1e-167 czcD P COG1230 Co Zn Cd efflux system component
IHFHMFKI_02934 4e-195 trkA P Oxidoreductase
IHFHMFKI_02937 1.8e-14 ykkA S Protein of unknown function (DUF664)
IHFHMFKI_02938 5.1e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
IHFHMFKI_02940 6.9e-195 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
IHFHMFKI_02941 2.6e-51 ydeH
IHFHMFKI_02942 2e-164 S Sodium Bile acid symporter family
IHFHMFKI_02943 4.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
IHFHMFKI_02944 1.8e-66 yraB K helix_turn_helix, mercury resistance
IHFHMFKI_02945 2.3e-224 mleN_2 C antiporter
IHFHMFKI_02946 6e-255 K helix_turn_helix gluconate operon transcriptional repressor
IHFHMFKI_02947 2.3e-113 paiB K Transcriptional regulator
IHFHMFKI_02949 1.9e-177 ydeR EGP Major facilitator Superfamily
IHFHMFKI_02950 1.6e-100 ydeS K Transcriptional regulator
IHFHMFKI_02951 1.4e-47 yraD M Spore coat protein
IHFHMFKI_02952 3.1e-24 yraE
IHFHMFKI_02953 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IHFHMFKI_02954 8.4e-63 yraF M Spore coat protein
IHFHMFKI_02955 1.3e-35 yraG
IHFHMFKI_02956 5.6e-215 ydfH 2.7.13.3 T Histidine kinase
IHFHMFKI_02957 6e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHFHMFKI_02958 0.0 ydfJ S drug exporters of the RND superfamily
IHFHMFKI_02959 6.7e-133 puuD S Peptidase C26
IHFHMFKI_02960 6.7e-298 expZ S ABC transporter
IHFHMFKI_02961 5.7e-97 ynaD J Acetyltransferase (GNAT) domain
IHFHMFKI_02962 2.5e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
IHFHMFKI_02963 2.7e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
IHFHMFKI_02964 1.8e-210 tcaB EGP Major facilitator Superfamily
IHFHMFKI_02965 3.7e-224 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IHFHMFKI_02966 5e-156 K Helix-turn-helix XRE-family like proteins
IHFHMFKI_02967 9.4e-122 ydhB S membrane transporter protein
IHFHMFKI_02968 2.2e-81 bltD 2.3.1.57 K FR47-like protein
IHFHMFKI_02969 9e-150 bltR K helix_turn_helix, mercury resistance
IHFHMFKI_02970 1.1e-148 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IHFHMFKI_02971 8.1e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
IHFHMFKI_02972 2.4e-144 ycgJ_1 Q ubiE/COQ5 methyltransferase family
IHFHMFKI_02973 6.1e-167 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Isocitrate/isopropylmalate dehydrogenase
IHFHMFKI_02974 6.9e-119 ydhC K FCD
IHFHMFKI_02975 1e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
IHFHMFKI_02978 1.1e-261 pbpE V Beta-lactamase
IHFHMFKI_02980 5.5e-98 ydhK M Protein of unknown function (DUF1541)
IHFHMFKI_02981 2e-195 pbuE EGP Major facilitator Superfamily
IHFHMFKI_02982 1.5e-132 ydhQ K UTRA
IHFHMFKI_02983 9.9e-118 K FCD
IHFHMFKI_02984 8.2e-216 yeaN P COG2807 Cyanate permease
IHFHMFKI_02985 2.6e-49 sugE P Small Multidrug Resistance protein
IHFHMFKI_02986 2.3e-51 ykkC P Small Multidrug Resistance protein
IHFHMFKI_02987 2.9e-102 yvdT K Transcriptional regulator
IHFHMFKI_02988 9.3e-297 yveA E amino acid
IHFHMFKI_02989 1.9e-163 ydhU P Catalase
IHFHMFKI_02990 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
IHFHMFKI_02991 7.5e-183 yhfP 1.1.1.1 C Quinone oxidoreductase
IHFHMFKI_02992 2.9e-249 iolT EGP Major facilitator Superfamily
IHFHMFKI_02995 9.4e-220 glcP G Major Facilitator Superfamily
IHFHMFKI_02996 5.5e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IHFHMFKI_02997 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
IHFHMFKI_02998 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
IHFHMFKI_02999 3.5e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
IHFHMFKI_03000 9.1e-173 ybaS 1.1.1.58 S Na -dependent transporter
IHFHMFKI_03001 1.9e-109 ybbA S Putative esterase
IHFHMFKI_03002 1.8e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_03003 8.1e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_03004 1.7e-171 feuA P Iron-uptake system-binding protein
IHFHMFKI_03005 2.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
IHFHMFKI_03006 3.3e-236 ybbC 3.2.1.52 S protein conserved in bacteria
IHFHMFKI_03007 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
IHFHMFKI_03008 5.2e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
IHFHMFKI_03009 8e-236 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IHFHMFKI_03010 2.9e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IHFHMFKI_03011 7.7e-85 ybbJ J acetyltransferase
IHFHMFKI_03012 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
IHFHMFKI_03018 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
IHFHMFKI_03019 2.9e-116 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
IHFHMFKI_03020 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IHFHMFKI_03021 1.5e-221 ybbR S protein conserved in bacteria
IHFHMFKI_03022 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IHFHMFKI_03023 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IHFHMFKI_03024 1.1e-153 V ATPases associated with a variety of cellular activities
IHFHMFKI_03025 3.7e-106 S ABC-2 family transporter protein
IHFHMFKI_03026 4.7e-99 ybdN
IHFHMFKI_03027 2.1e-131 ybdO S Domain of unknown function (DUF4885)
IHFHMFKI_03028 8.1e-162 dkgB S Aldo/keto reductase family
IHFHMFKI_03029 2.9e-93 yxaC M effector of murein hydrolase
IHFHMFKI_03030 6.9e-52 S LrgA family
IHFHMFKI_03031 4.9e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
IHFHMFKI_03032 2e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
IHFHMFKI_03033 3.3e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IHFHMFKI_03034 1.6e-104 T Histidine kinase
IHFHMFKI_03035 3.8e-82 KT helix_turn_helix, Lux Regulon
IHFHMFKI_03036 3.5e-134 V ABC transporter, ATP-binding protein
IHFHMFKI_03037 6.8e-146 V ABC-2 type transporter
IHFHMFKI_03038 6e-123 V ABC-2 type transporter
IHFHMFKI_03039 4.4e-14
IHFHMFKI_03040 1.1e-58 bacT Q Thioesterase domain
IHFHMFKI_03041 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
IHFHMFKI_03042 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
IHFHMFKI_03043 6.7e-120 fabD 2.3.1.39 I PFAM Acyl transferase
IHFHMFKI_03044 0.0 Q Beta-ketoacyl synthase
IHFHMFKI_03045 0.0 Q Polyketide synthase modules and related proteins
IHFHMFKI_03046 1.2e-102 Q Flavin containing amine oxidoreductase
IHFHMFKI_03047 0.0 Q TIGRFAM amino acid adenylation domain
IHFHMFKI_03048 6.1e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
IHFHMFKI_03049 2.5e-75 S Domain of unknown function (DUF4879)
IHFHMFKI_03050 8.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
IHFHMFKI_03051 8e-107 yqeB
IHFHMFKI_03052 9.2e-40 ybyB
IHFHMFKI_03053 1.2e-291 ybeC E amino acid
IHFHMFKI_03054 3.7e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IHFHMFKI_03055 1.7e-259 glpT G -transporter
IHFHMFKI_03056 1e-16 S Protein of unknown function (DUF2651)
IHFHMFKI_03057 3.3e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
IHFHMFKI_03059 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
IHFHMFKI_03060 2e-31
IHFHMFKI_03061 1.2e-82 K Helix-turn-helix XRE-family like proteins
IHFHMFKI_03062 2.7e-194 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
IHFHMFKI_03063 1.2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IHFHMFKI_03064 8.6e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IHFHMFKI_03065 1.9e-86 ybfM S SNARE associated Golgi protein
IHFHMFKI_03066 4.7e-151 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
IHFHMFKI_03067 3.9e-41 ybfN
IHFHMFKI_03068 2.5e-191 yceA S Belongs to the UPF0176 family
IHFHMFKI_03069 2.5e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IHFHMFKI_03070 9.5e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IHFHMFKI_03071 1.5e-256 mmuP E amino acid
IHFHMFKI_03072 8.7e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
IHFHMFKI_03073 2.7e-258 agcS E Sodium alanine symporter
IHFHMFKI_03074 5.9e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
IHFHMFKI_03075 1.1e-205 phoQ 2.7.13.3 T Histidine kinase
IHFHMFKI_03076 6.3e-171 glnL T Regulator
IHFHMFKI_03077 1.3e-125 ycbJ S Macrolide 2'-phosphotransferase
IHFHMFKI_03078 1.2e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
IHFHMFKI_03079 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IHFHMFKI_03080 2.2e-108 ydfN C nitroreductase
IHFHMFKI_03081 2.2e-184 ydfO E COG0346 Lactoylglutathione lyase and related lyases
IHFHMFKI_03082 1.5e-62 mhqP S DoxX
IHFHMFKI_03083 1.2e-55 traF CO Thioredoxin
IHFHMFKI_03084 5.6e-62 ycbP S Protein of unknown function (DUF2512)
IHFHMFKI_03085 5.3e-77 sleB 3.5.1.28 M Cell wall
IHFHMFKI_03086 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
IHFHMFKI_03087 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IHFHMFKI_03088 3.2e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHFHMFKI_03089 7.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IHFHMFKI_03090 2.3e-204 ycbU E Selenocysteine lyase
IHFHMFKI_03091 3e-241 lmrB EGP the major facilitator superfamily
IHFHMFKI_03092 1e-99 yxaF K Transcriptional regulator
IHFHMFKI_03093 1.6e-194 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
IHFHMFKI_03094 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
IHFHMFKI_03095 7e-195 yccF K DNA-templated transcriptional preinitiation complex assembly
IHFHMFKI_03096 1.8e-170 yccK C Aldo keto reductase
IHFHMFKI_03097 1.5e-175 ycdA S Domain of unknown function (DUF5105)
IHFHMFKI_03098 1.3e-254 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
IHFHMFKI_03099 1.6e-265 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
IHFHMFKI_03100 6.4e-90 cwlK M D-alanyl-D-alanine carboxypeptidase
IHFHMFKI_03101 1e-188 S response regulator aspartate phosphatase
IHFHMFKI_03102 3.1e-139 IQ Enoyl-(Acyl carrier protein) reductase
IHFHMFKI_03103 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
IHFHMFKI_03104 6.7e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
IHFHMFKI_03105 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
IHFHMFKI_03106 9.8e-136 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
IHFHMFKI_03107 2e-183 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHFHMFKI_03108 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
IHFHMFKI_03109 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
IHFHMFKI_03110 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
IHFHMFKI_03111 9.7e-138 terC P Protein of unknown function (DUF475)
IHFHMFKI_03112 0.0 yceG S Putative component of 'biosynthetic module'
IHFHMFKI_03113 2.3e-193 yceH P Belongs to the TelA family
IHFHMFKI_03114 1.1e-212 naiP P Uncharacterised MFS-type transporter YbfB
IHFHMFKI_03115 3.9e-229 proV 3.6.3.32 E glycine betaine
IHFHMFKI_03116 1.6e-138 opuAB P glycine betaine
IHFHMFKI_03117 2e-163 opuAC E glycine betaine
IHFHMFKI_03118 3.1e-209 amhX S amidohydrolase
IHFHMFKI_03119 2.5e-227 ycgA S Membrane
IHFHMFKI_03120 1.5e-80 ycgB
IHFHMFKI_03121 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
IHFHMFKI_03122 1.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IHFHMFKI_03123 8.1e-261 mdr EGP Major facilitator Superfamily
IHFHMFKI_03124 3.7e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
IHFHMFKI_03125 4.7e-114 ycgF E Lysine exporter protein LysE YggA
IHFHMFKI_03126 1.2e-151 yqcI S YqcI/YcgG family
IHFHMFKI_03127 5.4e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
IHFHMFKI_03128 7.6e-114 ycgI S Domain of unknown function (DUF1989)
IHFHMFKI_03129 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IHFHMFKI_03131 1.4e-107 tmrB S AAA domain
IHFHMFKI_03132 2.5e-141 4.2.1.118 G Xylose isomerase-like TIM barrel
IHFHMFKI_03133 1.8e-221 G COG0477 Permeases of the major facilitator superfamily
IHFHMFKI_03134 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IHFHMFKI_03135 6.5e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IHFHMFKI_03136 8.9e-147 ycgL S Predicted nucleotidyltransferase
IHFHMFKI_03137 8.7e-170 ycgM E Proline dehydrogenase
IHFHMFKI_03138 1.2e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
IHFHMFKI_03139 5.8e-245 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHFHMFKI_03140 1.2e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
IHFHMFKI_03141 4.9e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IHFHMFKI_03142 4.6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
IHFHMFKI_03143 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
IHFHMFKI_03144 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IHFHMFKI_03145 1.7e-226 yciC S GTPases (G3E family)
IHFHMFKI_03146 1.4e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
IHFHMFKI_03147 4.8e-73 yckC S membrane
IHFHMFKI_03148 1.3e-48 S Protein of unknown function (DUF2680)
IHFHMFKI_03149 1.5e-65 nin S Competence protein J (ComJ)
IHFHMFKI_03150 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
IHFHMFKI_03151 1.9e-82 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
IHFHMFKI_03152 2.4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
IHFHMFKI_03153 2.6e-61 hxlR K transcriptional
IHFHMFKI_03154 2.2e-78 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_03155 7.7e-39 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_03158 8.4e-09
IHFHMFKI_03159 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
IHFHMFKI_03160 2.9e-63 yncE S Protein of unknown function (DUF2691)
IHFHMFKI_03161 4.1e-127 Q ubiE/COQ5 methyltransferase family
IHFHMFKI_03162 3.1e-201 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
IHFHMFKI_03163 7e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
IHFHMFKI_03165 1.9e-164 K helix_turn_helix, mercury resistance
IHFHMFKI_03166 2.7e-185 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
IHFHMFKI_03167 5.2e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
IHFHMFKI_03168 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
IHFHMFKI_03169 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
IHFHMFKI_03170 1.5e-160 yurL 2.7.1.218 G pfkB family carbohydrate kinase
IHFHMFKI_03171 3.6e-134 yurK K UTRA
IHFHMFKI_03172 2.7e-205 msmX P Belongs to the ABC transporter superfamily
IHFHMFKI_03173 1.6e-165 bsn L Ribonuclease
IHFHMFKI_03174 4.4e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
IHFHMFKI_03175 6.2e-235 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
IHFHMFKI_03176 4.1e-212 blt EGP Major facilitator Superfamily
IHFHMFKI_03178 1.5e-21
IHFHMFKI_03179 3.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
IHFHMFKI_03180 1.2e-260 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
IHFHMFKI_03181 2.4e-59 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
IHFHMFKI_03182 1.5e-168 yunF S Protein of unknown function DUF72
IHFHMFKI_03183 1.1e-144 yunE S membrane transporter protein
IHFHMFKI_03184 2.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IHFHMFKI_03185 3.3e-130 yunB S Sporulation protein YunB (Spo_YunB)
IHFHMFKI_03186 6.6e-192 lytH M Peptidase, M23
IHFHMFKI_03187 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IHFHMFKI_03188 1.7e-47 yutD S protein conserved in bacteria
IHFHMFKI_03189 6.8e-72 yutE S Protein of unknown function DUF86
IHFHMFKI_03190 3.6e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IHFHMFKI_03191 3.3e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
IHFHMFKI_03192 3e-195 yutH S Spore coat protein
IHFHMFKI_03193 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
IHFHMFKI_03194 1.7e-196 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IHFHMFKI_03195 9.8e-169 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IHFHMFKI_03196 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
IHFHMFKI_03197 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
IHFHMFKI_03198 1.1e-53 yuzD S protein conserved in bacteria
IHFHMFKI_03199 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
IHFHMFKI_03200 2.4e-39 yuzB S Belongs to the UPF0349 family
IHFHMFKI_03201 5e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IHFHMFKI_03202 1.4e-161 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IHFHMFKI_03203 1.1e-62 erpA S Belongs to the HesB IscA family
IHFHMFKI_03204 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
IHFHMFKI_03205 1e-26 K helix_turn_helix, mercury resistance
IHFHMFKI_03207 2.9e-33 S Bacteriocin class IId cyclical uberolysin-like
IHFHMFKI_03209 1.5e-121 V ABC transporter
IHFHMFKI_03210 2.6e-70 CP Membrane
IHFHMFKI_03211 4.8e-29
IHFHMFKI_03212 5.7e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IHFHMFKI_03214 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
IHFHMFKI_03215 1.1e-236 yumB 1.6.99.3 C NADH dehydrogenase
IHFHMFKI_03216 9.9e-28 yuiB S Putative membrane protein
IHFHMFKI_03217 2.7e-117 yuiC S protein conserved in bacteria
IHFHMFKI_03218 1.6e-77 yuiD S protein conserved in bacteria
IHFHMFKI_03219 6.8e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IHFHMFKI_03220 3.1e-208 yuiF S antiporter
IHFHMFKI_03221 1.1e-101 bioY S Biotin biosynthesis protein
IHFHMFKI_03222 3.2e-120 yuiH S Oxidoreductase molybdopterin binding domain
IHFHMFKI_03223 1.2e-163 besA S Putative esterase
IHFHMFKI_03224 5.3e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IHFHMFKI_03225 8.6e-218 entC 5.4.4.2 HQ Isochorismate synthase
IHFHMFKI_03226 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
IHFHMFKI_03227 3.6e-171 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
IHFHMFKI_03228 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_03229 1.1e-33 mbtH S MbtH-like protein
IHFHMFKI_03230 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
IHFHMFKI_03231 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
IHFHMFKI_03232 4.2e-228 yukF QT Transcriptional regulator
IHFHMFKI_03233 3.3e-46 esxA S Belongs to the WXG100 family
IHFHMFKI_03234 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
IHFHMFKI_03235 1.2e-204 essB S WXG100 protein secretion system (Wss), protein YukC
IHFHMFKI_03236 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
IHFHMFKI_03237 0.0 esaA S type VII secretion protein EsaA
IHFHMFKI_03238 6.5e-76 yueC S Family of unknown function (DUF5383)
IHFHMFKI_03239 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_03240 8.3e-96 yueE S phosphohydrolase
IHFHMFKI_03241 1.6e-22 S Protein of unknown function (DUF2642)
IHFHMFKI_03242 3.6e-186 yueF S transporter activity
IHFHMFKI_03243 6.4e-34 yueG S Spore germination protein gerPA/gerPF
IHFHMFKI_03244 2.8e-38 yueH S YueH-like protein
IHFHMFKI_03245 7.2e-68 yueI S Protein of unknown function (DUF1694)
IHFHMFKI_03246 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
IHFHMFKI_03247 7.2e-283 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IHFHMFKI_03248 3.8e-229 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
IHFHMFKI_03249 1.2e-50 yuzC
IHFHMFKI_03252 8.9e-98 comQ H Belongs to the FPP GGPP synthase family
IHFHMFKI_03254 1.2e-276 comP 2.7.13.3 T Histidine kinase
IHFHMFKI_03255 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHFHMFKI_03256 1.1e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
IHFHMFKI_03257 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
IHFHMFKI_03258 1.9e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IHFHMFKI_03259 8.5e-76 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IHFHMFKI_03260 1.7e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IHFHMFKI_03261 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IHFHMFKI_03262 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
IHFHMFKI_03263 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
IHFHMFKI_03264 2.3e-12
IHFHMFKI_03265 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
IHFHMFKI_03266 8.4e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
IHFHMFKI_03267 1e-284 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
IHFHMFKI_03268 1.7e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
IHFHMFKI_03269 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
IHFHMFKI_03270 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IHFHMFKI_03271 9.3e-74 yufK S Family of unknown function (DUF5366)
IHFHMFKI_03272 2.2e-72 yuxK S protein conserved in bacteria
IHFHMFKI_03273 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
IHFHMFKI_03274 4.5e-185 yuxJ EGP Major facilitator Superfamily
IHFHMFKI_03275 4e-118 kapD L the KinA pathway to sporulation
IHFHMFKI_03276 7.7e-67 kapB G Kinase associated protein B
IHFHMFKI_03277 8.9e-229 T PhoQ Sensor
IHFHMFKI_03278 1.3e-223 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
IHFHMFKI_03279 1.4e-40 yugE S Domain of unknown function (DUF1871)
IHFHMFKI_03280 5.5e-155 yugF I Hydrolase
IHFHMFKI_03281 2e-83 alaR K Transcriptional regulator
IHFHMFKI_03282 1.6e-208 yugH 2.6.1.1 E Aminotransferase
IHFHMFKI_03283 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
IHFHMFKI_03284 1.8e-34 yuzA S Domain of unknown function (DUF378)
IHFHMFKI_03285 1.6e-224 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
IHFHMFKI_03286 1.4e-228 yugK C Dehydrogenase
IHFHMFKI_03287 5.5e-118 ycaC Q Isochorismatase family
IHFHMFKI_03288 4.1e-93 S NADPH-dependent FMN reductase
IHFHMFKI_03289 1.5e-258 pgi 5.3.1.9 G Belongs to the GPI family
IHFHMFKI_03291 7e-71 yugN S YugN-like family
IHFHMFKI_03292 1.8e-181 yugO P COG1226 Kef-type K transport systems
IHFHMFKI_03293 6.7e-27 mstX S Membrane-integrating protein Mistic
IHFHMFKI_03294 3.4e-18
IHFHMFKI_03295 8.3e-117 yugP S Zn-dependent protease
IHFHMFKI_03296 2.5e-231 yugS S COG1253 Hemolysins and related proteins containing CBS domains
IHFHMFKI_03297 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
IHFHMFKI_03298 2.7e-73 yugU S Uncharacterised protein family UPF0047
IHFHMFKI_03299 2.3e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
IHFHMFKI_03300 1.4e-40
IHFHMFKI_03301 4.9e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
IHFHMFKI_03302 8.1e-221 mcpA NT chemotaxis protein
IHFHMFKI_03303 5.8e-235 mcpA NT chemotaxis protein
IHFHMFKI_03304 6e-224 mcpA NT chemotaxis protein
IHFHMFKI_03305 2.6e-235 mcpA NT chemotaxis protein
IHFHMFKI_03306 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
IHFHMFKI_03307 2.1e-185 ygjR S Oxidoreductase
IHFHMFKI_03308 2.2e-194 yubA S transporter activity
IHFHMFKI_03309 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IHFHMFKI_03311 3.4e-52 yjcN
IHFHMFKI_03312 3.5e-117 G Cupin
IHFHMFKI_03313 3.2e-217 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IHFHMFKI_03314 9e-145 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IHFHMFKI_03315 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
IHFHMFKI_03316 7.9e-94 yuaB
IHFHMFKI_03317 8.6e-96 yuaC K Belongs to the GbsR family
IHFHMFKI_03318 3.2e-283 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
IHFHMFKI_03319 7.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
IHFHMFKI_03320 2.5e-109 yuaD S MOSC domain
IHFHMFKI_03321 6.9e-73 yuaE S DinB superfamily
IHFHMFKI_03322 7.3e-84 yuaF OU Membrane protein implicated in regulation of membrane protease activity
IHFHMFKI_03323 5e-178 yuaG 3.4.21.72 S protein conserved in bacteria
IHFHMFKI_03324 8.2e-97 thiT S Thiamine transporter protein (Thia_YuaJ)
IHFHMFKI_03325 5.2e-27 Q PFAM Collagen triple helix
IHFHMFKI_03326 6e-234 yflS P Sodium:sulfate symporter transmembrane region
IHFHMFKI_03327 1e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
IHFHMFKI_03328 1.3e-57 yflT S Heat induced stress protein YflT
IHFHMFKI_03329 2.7e-24 S Protein of unknown function (DUF3212)
IHFHMFKI_03330 2.3e-187 yfmJ S N-terminal domain of oxidoreductase
IHFHMFKI_03331 2.1e-41 yfmK 2.3.1.128 K acetyltransferase
IHFHMFKI_03332 1.7e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
IHFHMFKI_03333 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IHFHMFKI_03334 9.8e-206 yfmO EGP Major facilitator Superfamily
IHFHMFKI_03335 1.8e-69 yfmP K transcriptional
IHFHMFKI_03336 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
IHFHMFKI_03337 1.2e-207 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IHFHMFKI_03338 5.8e-166 IQ Enoyl-(Acyl carrier protein) reductase
IHFHMFKI_03339 7.5e-107 yfmS NT chemotaxis protein
IHFHMFKI_03340 3.8e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
IHFHMFKI_03341 3e-246 yfnA E amino acid
IHFHMFKI_03342 1.4e-210 fsr P COG0477 Permeases of the major facilitator superfamily
IHFHMFKI_03343 1.5e-185 yfnD M Nucleotide-diphospho-sugar transferase
IHFHMFKI_03344 9.9e-219 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
IHFHMFKI_03345 1.3e-178 yfnF M Nucleotide-diphospho-sugar transferase
IHFHMFKI_03346 2.4e-172 yfnG 4.2.1.45 M dehydratase
IHFHMFKI_03347 1.8e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
IHFHMFKI_03348 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IHFHMFKI_03349 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
IHFHMFKI_03350 3.4e-197 yetN S Protein of unknown function (DUF3900)
IHFHMFKI_03351 4.3e-203 yetM CH FAD binding domain
IHFHMFKI_03352 8e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
IHFHMFKI_03354 2.4e-105 yetJ S Belongs to the BI1 family
IHFHMFKI_03355 2.6e-54 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
IHFHMFKI_03356 3.4e-22 yezD S Uncharacterized small protein (DUF2292)
IHFHMFKI_03357 3.7e-154 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
IHFHMFKI_03358 3.7e-63 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IHFHMFKI_03359 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
IHFHMFKI_03360 7.4e-121 yetF S membrane
IHFHMFKI_03362 2e-94 yesJ K Acetyltransferase (GNAT) family
IHFHMFKI_03363 8.9e-104 cotJC P Spore Coat
IHFHMFKI_03364 1.3e-44 cotJB S CotJB protein
IHFHMFKI_03365 1.2e-44 cotJA S Spore coat associated protein JA (CotJA)
IHFHMFKI_03366 9e-108 aadK G Streptomycin adenylyltransferase
IHFHMFKI_03368 9.4e-127 yeeN K transcriptional regulatory protein
IHFHMFKI_03369 1.1e-20
IHFHMFKI_03370 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
IHFHMFKI_03371 2.7e-85 S Protein of unknown function, DUF600
IHFHMFKI_03372 3.3e-37 S Protein of unknown function, DUF600
IHFHMFKI_03373 2.2e-138 cylB V ABC-2 type transporter
IHFHMFKI_03374 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
IHFHMFKI_03375 4.5e-21
IHFHMFKI_03376 4.2e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHFHMFKI_03377 6.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
IHFHMFKI_03378 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IHFHMFKI_03379 1.9e-150 yerO K Transcriptional regulator
IHFHMFKI_03380 3.4e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHFHMFKI_03381 4.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IHFHMFKI_03382 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IHFHMFKI_03383 4.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IHFHMFKI_03384 1.3e-120 sapB S MgtC SapB transporter
IHFHMFKI_03385 6.1e-193 yerI S homoserine kinase type II (protein kinase fold)
IHFHMFKI_03386 2e-222 camS S COG4851 Protein involved in sex pheromone biosynthesis
IHFHMFKI_03387 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IHFHMFKI_03388 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IHFHMFKI_03389 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
IHFHMFKI_03390 7.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
IHFHMFKI_03391 2.4e-50 yerC S protein conserved in bacteria
IHFHMFKI_03392 1.5e-191 yerB S Protein of unknown function (DUF3048) C-terminal domain
IHFHMFKI_03393 0.0 yerA 3.5.4.2 F adenine deaminase
IHFHMFKI_03394 2.6e-25 S Protein of unknown function (DUF2892)
IHFHMFKI_03395 1.2e-233 purD 6.3.4.13 F Belongs to the GARS family
IHFHMFKI_03396 5e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IHFHMFKI_03397 9.1e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IHFHMFKI_03398 1.9e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IHFHMFKI_03399 1.2e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IHFHMFKI_03400 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHFHMFKI_03401 1.5e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHFHMFKI_03402 2.2e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IHFHMFKI_03403 3.8e-128 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IHFHMFKI_03404 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IHFHMFKI_03405 3e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IHFHMFKI_03406 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IHFHMFKI_03407 5.5e-29 yebG S NETI protein
IHFHMFKI_03408 7.5e-92 yebE S UPF0316 protein
IHFHMFKI_03410 1.5e-125 yebC M Membrane
IHFHMFKI_03411 8.1e-209 pbuG S permease
IHFHMFKI_03412 1e-249 S Domain of unknown function (DUF4179)
IHFHMFKI_03413 5e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IHFHMFKI_03414 1.1e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IHFHMFKI_03415 0.0 yebA E COG1305 Transglutaminase-like enzymes
IHFHMFKI_03416 1.1e-206 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
IHFHMFKI_03417 2.1e-174 yeaC S COG0714 MoxR-like ATPases
IHFHMFKI_03418 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
IHFHMFKI_03419 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
IHFHMFKI_03420 7.2e-35 ydjO S Cold-inducible protein YdjO
IHFHMFKI_03422 2e-133 ydjN U Involved in the tonB-independent uptake of proteins
IHFHMFKI_03423 1.2e-61 ydjM M Lytic transglycolase
IHFHMFKI_03424 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
IHFHMFKI_03425 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
IHFHMFKI_03426 1.4e-145 rsiV S Protein of unknown function (DUF3298)
IHFHMFKI_03427 0.0 yrhL I Acyltransferase family
IHFHMFKI_03428 1.8e-144 ydjI S virion core protein (lumpy skin disease virus)
IHFHMFKI_03429 2.9e-118 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
IHFHMFKI_03430 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IHFHMFKI_03431 1.3e-112 pspA KT Phage shock protein A
IHFHMFKI_03432 3.1e-29 yjdJ S Domain of unknown function (DUF4306)
IHFHMFKI_03433 3.7e-171 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
IHFHMFKI_03434 1.4e-248 gutA G MFS/sugar transport protein
IHFHMFKI_03435 5e-201 gutB 1.1.1.14 E Dehydrogenase
IHFHMFKI_03436 0.0 K NB-ARC domain
IHFHMFKI_03437 1.5e-24 S Protein of unknown function (DUF4064)
IHFHMFKI_03438 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IHFHMFKI_03439 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IHFHMFKI_03440 9.6e-127 ydiL S CAAX protease self-immunity
IHFHMFKI_03441 1.7e-27 ydiK S Domain of unknown function (DUF4305)
IHFHMFKI_03442 3.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IHFHMFKI_03443 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
IHFHMFKI_03444 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IHFHMFKI_03445 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
IHFHMFKI_03446 0.0 ydiF S ABC transporter
IHFHMFKI_03447 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IHFHMFKI_03448 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IHFHMFKI_03449 4.6e-123 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
IHFHMFKI_03450 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
IHFHMFKI_03451 1.3e-182 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IHFHMFKI_03453 5.7e-29 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IHFHMFKI_03455 2.8e-26
IHFHMFKI_03456 8.4e-09
IHFHMFKI_03457 3.7e-48 yrdF K ribonuclease inhibitor
IHFHMFKI_03458 3.4e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IHFHMFKI_03459 3.8e-162 ytlI K LysR substrate binding domain
IHFHMFKI_03460 3e-101 ytmI K Acetyltransferase (GNAT) domain
IHFHMFKI_03461 3.9e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
IHFHMFKI_03462 2.7e-146 tcyK M Bacterial periplasmic substrate-binding proteins
IHFHMFKI_03463 5e-120 tcyL P Binding-protein-dependent transport system inner membrane component
IHFHMFKI_03464 8.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
IHFHMFKI_03465 1e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
IHFHMFKI_03466 3.2e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHFHMFKI_03467 5.6e-46 ytnI O COG0695 Glutaredoxin and related proteins
IHFHMFKI_03468 8.3e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IHFHMFKI_03469 1.5e-141 S Amidohydrolase
IHFHMFKI_03470 2.4e-66 4.1.1.44 S Carboxymuconolactone decarboxylase family
IHFHMFKI_03471 2.2e-216 ynfM EGP Major Facilitator Superfamily
IHFHMFKI_03472 8.4e-159 K Helix-turn-helix XRE-family like proteins
IHFHMFKI_03473 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IHFHMFKI_03474 4.6e-191 yvaA 1.1.1.371 S Oxidoreductase
IHFHMFKI_03475 3.7e-48 csoR S transcriptional
IHFHMFKI_03476 2.6e-29 copZ P Heavy-metal-associated domain
IHFHMFKI_03477 0.0 copA 3.6.3.54 P P-type ATPase
IHFHMFKI_03478 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
IHFHMFKI_03479 2.4e-100 bdbD O Thioredoxin
IHFHMFKI_03480 6e-73 bdbC O Required for disulfide bond formation in some proteins
IHFHMFKI_03481 1.1e-139 S Metallo-peptidase family M12
IHFHMFKI_03482 2.3e-105 yvgT S membrane
IHFHMFKI_03483 0.0 helD 3.6.4.12 L DNA helicase
IHFHMFKI_03484 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IHFHMFKI_03485 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
IHFHMFKI_03486 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
IHFHMFKI_03487 2.7e-85 yvgO
IHFHMFKI_03488 5e-156 yvgN S reductase
IHFHMFKI_03489 7e-193 yfiN V COG0842 ABC-type multidrug transport system, permease component
IHFHMFKI_03490 1.3e-191 yfiM V ABC-2 type transporter
IHFHMFKI_03491 1.8e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
IHFHMFKI_03492 4.3e-179 T Histidine kinase
IHFHMFKI_03493 8.6e-114 yfiK K Regulator
IHFHMFKI_03494 7.9e-99 modB P COG4149 ABC-type molybdate transport system, permease component
IHFHMFKI_03495 2.6e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
IHFHMFKI_03496 2.3e-165 yvgK P COG1910 Periplasmic molybdate-binding protein domain
IHFHMFKI_03497 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IHFHMFKI_03498 5.1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
IHFHMFKI_03499 5.2e-13 S Small spore protein J (Spore_SspJ)
IHFHMFKI_03500 2.9e-236 yvsH E Arginine ornithine antiporter
IHFHMFKI_03501 1.6e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IHFHMFKI_03502 2.6e-177 fhuD P ABC transporter
IHFHMFKI_03503 1.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_03504 7.6e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_03505 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
IHFHMFKI_03506 9.3e-66 yvrL S Regulatory protein YrvL
IHFHMFKI_03507 7.8e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
IHFHMFKI_03508 6.1e-15 S YvrJ protein family
IHFHMFKI_03509 3.8e-102 yvrI K RNA polymerase
IHFHMFKI_03510 1.1e-36
IHFHMFKI_03511 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_03512 0.0 T PhoQ Sensor
IHFHMFKI_03513 1.1e-169 yvrE G SMP-30/Gluconolaconase/LRE-like region
IHFHMFKI_03514 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IHFHMFKI_03515 1e-165 yvrC P ABC transporter substrate-binding protein
IHFHMFKI_03516 5.8e-178 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IHFHMFKI_03517 1.4e-218 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
IHFHMFKI_03518 2.7e-100 yvqK 2.5.1.17 S Adenosyltransferase
IHFHMFKI_03519 1.8e-226 yvqJ EGP Major facilitator Superfamily
IHFHMFKI_03520 5.3e-44 liaI S membrane
IHFHMFKI_03521 1.5e-89 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
IHFHMFKI_03522 7.4e-126 liaG S Putative adhesin
IHFHMFKI_03523 8.6e-128 yvqF S Cell wall-active antibiotics response 4TMS YvqF
IHFHMFKI_03524 2.3e-193 vraS 2.7.13.3 T Histidine kinase
IHFHMFKI_03525 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
IHFHMFKI_03526 6e-205 gerAC S Spore germination B3/ GerAC like, C-terminal
IHFHMFKI_03527 3.6e-186 gerAB E Spore germination protein
IHFHMFKI_03528 3.5e-258 gerAA EG Spore germination protein
IHFHMFKI_03529 6.6e-24 S Protein of unknown function (DUF3970)
IHFHMFKI_03530 8.7e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IHFHMFKI_03531 6.5e-157 yuxN K Transcriptional regulator
IHFHMFKI_03532 3.4e-24
IHFHMFKI_03533 2.2e-249 cssS 2.7.13.3 T PhoQ Sensor
IHFHMFKI_03534 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
IHFHMFKI_03535 5e-238 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IHFHMFKI_03536 4.7e-79 dps P Belongs to the Dps family
IHFHMFKI_03537 2.7e-149 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
IHFHMFKI_03538 0.0 pepF2 E COG1164 Oligoendopeptidase F
IHFHMFKI_03539 7.2e-45 S YusW-like protein
IHFHMFKI_03540 3.1e-150 yusV 3.6.3.34 HP ABC transporter
IHFHMFKI_03541 3.3e-39 yusU S Protein of unknown function (DUF2573)
IHFHMFKI_03542 7.1e-184 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IHFHMFKI_03543 4.2e-138 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IHFHMFKI_03544 8.5e-154 ywbI2 K Transcriptional regulator
IHFHMFKI_03545 1.4e-287 yusP P Major facilitator superfamily
IHFHMFKI_03546 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
IHFHMFKI_03547 1.1e-53 yusN M Coat F domain
IHFHMFKI_03548 1.1e-42
IHFHMFKI_03549 8.9e-210 yusP P Major facilitator superfamily
IHFHMFKI_03550 4.9e-165 fadM E Proline dehydrogenase
IHFHMFKI_03551 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
IHFHMFKI_03552 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
IHFHMFKI_03553 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
IHFHMFKI_03554 2.1e-63 arsC 1.20.4.1 P Belongs to the ArsC family
IHFHMFKI_03555 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
IHFHMFKI_03556 3.7e-40 yusG S Protein of unknown function (DUF2553)
IHFHMFKI_03557 4.9e-63 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
IHFHMFKI_03558 1.6e-54 yusE CO Thioredoxin
IHFHMFKI_03559 1.5e-56 yusD S SCP-2 sterol transfer family
IHFHMFKI_03560 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IHFHMFKI_03561 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
IHFHMFKI_03562 3e-145 metQ P Belongs to the NlpA lipoprotein family
IHFHMFKI_03563 3.8e-63 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IHFHMFKI_03564 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
IHFHMFKI_03565 1.2e-244 sufD O assembly protein SufD
IHFHMFKI_03566 2.1e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IHFHMFKI_03567 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
IHFHMFKI_03568 8.7e-270 sufB O FeS cluster assembly
IHFHMFKI_03569 1.4e-115 int L Belongs to the 'phage' integrase family
IHFHMFKI_03570 8.8e-47
IHFHMFKI_03572 4.6e-43 K Helix-turn-helix XRE-family like proteins
IHFHMFKI_03573 1.5e-14
IHFHMFKI_03575 3.8e-69 L dnaD_dom DnaD domain protein
IHFHMFKI_03576 1.7e-42 dnaC L IstB-like ATP binding protein
IHFHMFKI_03579 9e-29
IHFHMFKI_03582 3.6e-15 yqaO S Phage-like element PBSX protein XtrA
IHFHMFKI_03584 6.3e-27
IHFHMFKI_03586 1.2e-87
IHFHMFKI_03587 5.9e-10
IHFHMFKI_03589 1.2e-142 M cell wall anchor domain
IHFHMFKI_03590 4.6e-80 srtA 3.4.22.70 M Sortase family
IHFHMFKI_03591 3.7e-272 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
IHFHMFKI_03592 2.6e-118 citT T response regulator
IHFHMFKI_03593 4.6e-177 yflP S Tripartite tricarboxylate transporter family receptor
IHFHMFKI_03594 1e-224 citM C Citrate transporter
IHFHMFKI_03595 4.8e-148 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
IHFHMFKI_03596 6.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
IHFHMFKI_03597 4.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IHFHMFKI_03598 3.7e-122 yflK S protein conserved in bacteria
IHFHMFKI_03599 1.5e-14 yflJ S Protein of unknown function (DUF2639)
IHFHMFKI_03600 7e-19 yflI
IHFHMFKI_03601 3.1e-50 yflH S Protein of unknown function (DUF3243)
IHFHMFKI_03602 7.2e-138 map 3.4.11.18 E Methionine aminopeptidase
IHFHMFKI_03603 2.3e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
IHFHMFKI_03604 1.4e-72 yfmQ S Uncharacterised protein from bacillus cereus group
IHFHMFKI_03605 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
IHFHMFKI_03606 2.3e-63 yhdN S Domain of unknown function (DUF1992)
IHFHMFKI_03607 1.2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
IHFHMFKI_03608 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
IHFHMFKI_03609 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
IHFHMFKI_03610 2.8e-239 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IHFHMFKI_03611 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
IHFHMFKI_03612 2e-129 treR K transcriptional
IHFHMFKI_03613 1.2e-123 yfkO C nitroreductase
IHFHMFKI_03614 8.7e-123 yibF S YibE/F-like protein
IHFHMFKI_03615 3.8e-199 yibE S YibE/F-like protein
IHFHMFKI_03616 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
IHFHMFKI_03617 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
IHFHMFKI_03618 1.3e-185 K helix_turn _helix lactose operon repressor
IHFHMFKI_03619 5.6e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IHFHMFKI_03620 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IHFHMFKI_03621 8.1e-192 ydiM EGP Major facilitator Superfamily
IHFHMFKI_03622 2.7e-29 yfkK S Belongs to the UPF0435 family
IHFHMFKI_03623 4.1e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IHFHMFKI_03624 1e-51 yfkI S gas vesicle protein
IHFHMFKI_03625 7.6e-144 yihY S Belongs to the UPF0761 family
IHFHMFKI_03626 2.5e-07
IHFHMFKI_03627 2.5e-217 ycaD EGP COG0477 Permeases of the major facilitator superfamily
IHFHMFKI_03628 2.2e-185 cax P COG0387 Ca2 H antiporter
IHFHMFKI_03629 1.6e-143 yfkD S YfkD-like protein
IHFHMFKI_03630 6.8e-145 yfkC M Mechanosensitive ion channel
IHFHMFKI_03631 7.3e-219 yfkA S YfkB-like domain
IHFHMFKI_03632 4.9e-27 yfjT
IHFHMFKI_03633 9e-155 pdaA G deacetylase
IHFHMFKI_03634 7.5e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
IHFHMFKI_03635 7.4e-30
IHFHMFKI_03636 8.5e-184 corA P Mediates influx of magnesium ions
IHFHMFKI_03637 7.5e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IHFHMFKI_03638 6.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IHFHMFKI_03639 5.8e-44 S YfzA-like protein
IHFHMFKI_03640 3.5e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHFHMFKI_03641 3.7e-87 yfjM S Psort location Cytoplasmic, score
IHFHMFKI_03642 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
IHFHMFKI_03643 8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
IHFHMFKI_03644 1.9e-212 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IHFHMFKI_03645 6.2e-252 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
IHFHMFKI_03646 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
IHFHMFKI_03647 2.7e-14 sspH S Belongs to the SspH family
IHFHMFKI_03648 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
IHFHMFKI_03649 5.1e-139 glvR F Helix-turn-helix domain, rpiR family
IHFHMFKI_03650 1.8e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
IHFHMFKI_03651 2.4e-309 yfiB3 V ABC transporter
IHFHMFKI_03652 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
IHFHMFKI_03653 9.2e-63 mhqP S DoxX
IHFHMFKI_03654 2.5e-158 yfiE 1.13.11.2 S glyoxalase
IHFHMFKI_03655 1.7e-163 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
IHFHMFKI_03656 1.1e-95 padR K transcriptional
IHFHMFKI_03657 7.9e-111 1.6.5.2 S NADPH-dependent FMN reductase
IHFHMFKI_03658 3.2e-179 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
IHFHMFKI_03659 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
IHFHMFKI_03660 4.5e-45 yrdF K ribonuclease inhibitor
IHFHMFKI_03661 2.9e-96 yfiT S Belongs to the metal hydrolase YfiT family
IHFHMFKI_03662 4.7e-288 yfiU EGP Major facilitator Superfamily
IHFHMFKI_03663 6.2e-82 yfiV K transcriptional
IHFHMFKI_03664 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IHFHMFKI_03665 7.2e-161 yfhB 5.3.3.17 S PhzF family
IHFHMFKI_03666 1.7e-105 yfhC C nitroreductase
IHFHMFKI_03667 2.1e-25 yfhD S YfhD-like protein
IHFHMFKI_03669 2.2e-165 yfhF S nucleoside-diphosphate sugar epimerase
IHFHMFKI_03670 6.7e-142 recX 2.4.1.337 GT4 S Modulates RecA activity
IHFHMFKI_03671 2.5e-52 yfhH S Protein of unknown function (DUF1811)
IHFHMFKI_03672 1.1e-204 yfhI EGP Major facilitator Superfamily
IHFHMFKI_03674 2e-166 mpr 3.4.21.19 M Belongs to the peptidase S1B family
IHFHMFKI_03675 2.2e-44 yfhJ S WVELL protein
IHFHMFKI_03676 1.5e-92 batE T Bacterial SH3 domain homologues
IHFHMFKI_03677 2e-31 yfhL S SdpI/YhfL protein family
IHFHMFKI_03678 1.7e-170 yfhM S Alpha/beta hydrolase family
IHFHMFKI_03679 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
IHFHMFKI_03680 0.0 yfhO S Bacterial membrane protein YfhO
IHFHMFKI_03681 1e-184 yfhP S membrane-bound metal-dependent
IHFHMFKI_03682 4.8e-207 mutY L A G-specific
IHFHMFKI_03683 3.1e-36 yfhS
IHFHMFKI_03684 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
IHFHMFKI_03686 1.5e-37 ygaB S YgaB-like protein
IHFHMFKI_03687 2.2e-104 ygaC J Belongs to the UPF0374 family
IHFHMFKI_03688 5e-299 ygaD V ABC transporter
IHFHMFKI_03689 2.7e-178 ygaE S Membrane
IHFHMFKI_03690 3.1e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
IHFHMFKI_03691 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
IHFHMFKI_03692 1.8e-80 perR P Belongs to the Fur family
IHFHMFKI_03693 1.5e-56 ygzB S UPF0295 protein
IHFHMFKI_03694 1.1e-164 ygxA S Nucleotidyltransferase-like
IHFHMFKI_03695 6e-132 pdaB 3.5.1.104 G Polysaccharide deacetylase
IHFHMFKI_03696 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
IHFHMFKI_03697 1.7e-75 gerD
IHFHMFKI_03698 8.7e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
IHFHMFKI_03699 2.1e-134 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
IHFHMFKI_03700 1.4e-77 ybaK S Protein of unknown function (DUF2521)
IHFHMFKI_03701 1.2e-82 yizA S Damage-inducible protein DinB
IHFHMFKI_03702 4.5e-143 ybaJ Q Methyltransferase domain
IHFHMFKI_03703 6.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
IHFHMFKI_03704 1.9e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IHFHMFKI_03705 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IHFHMFKI_03706 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHFHMFKI_03707 9.6e-150 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHFHMFKI_03708 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IHFHMFKI_03709 4.7e-58 rplQ J Ribosomal protein L17
IHFHMFKI_03710 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHFHMFKI_03711 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IHFHMFKI_03712 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IHFHMFKI_03713 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IHFHMFKI_03714 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IHFHMFKI_03715 4.1e-141 map 3.4.11.18 E Methionine aminopeptidase
IHFHMFKI_03716 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IHFHMFKI_03717 3.9e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IHFHMFKI_03718 4.1e-72 rplO J binds to the 23S rRNA
IHFHMFKI_03719 1.9e-23 rpmD J Ribosomal protein L30
IHFHMFKI_03720 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IHFHMFKI_03721 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IHFHMFKI_03722 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IHFHMFKI_03723 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IHFHMFKI_03724 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IHFHMFKI_03725 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IHFHMFKI_03726 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IHFHMFKI_03727 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IHFHMFKI_03728 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IHFHMFKI_03729 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IHFHMFKI_03730 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IHFHMFKI_03731 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IHFHMFKI_03732 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IHFHMFKI_03733 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IHFHMFKI_03734 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IHFHMFKI_03735 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IHFHMFKI_03736 3e-105 rplD J Forms part of the polypeptide exit tunnel
IHFHMFKI_03737 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IHFHMFKI_03738 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IHFHMFKI_03739 1.2e-182 ybaC 3.4.11.5 S Alpha/beta hydrolase family
IHFHMFKI_03740 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IHFHMFKI_03741 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IHFHMFKI_03742 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IHFHMFKI_03743 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IHFHMFKI_03744 5.5e-34 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
IHFHMFKI_03745 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHFHMFKI_03746 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IHFHMFKI_03747 1.8e-107 rsmC 2.1.1.172 J Methyltransferase
IHFHMFKI_03748 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IHFHMFKI_03749 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IHFHMFKI_03750 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IHFHMFKI_03751 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IHFHMFKI_03752 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
IHFHMFKI_03753 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IHFHMFKI_03754 8.9e-116 sigH K Belongs to the sigma-70 factor family
IHFHMFKI_03755 4.2e-89 yacP S RNA-binding protein containing a PIN domain
IHFHMFKI_03756 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IHFHMFKI_03757 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IHFHMFKI_03758 6.2e-268 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IHFHMFKI_03759 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
IHFHMFKI_03760 5.3e-278 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IHFHMFKI_03761 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
IHFHMFKI_03762 1.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
IHFHMFKI_03763 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
IHFHMFKI_03764 1.9e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
IHFHMFKI_03765 1e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IHFHMFKI_03766 0.0 clpC O Belongs to the ClpA ClpB family
IHFHMFKI_03767 1.9e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
IHFHMFKI_03768 6e-64 mcsA 2.7.14.1 S protein with conserved CXXC pairs
IHFHMFKI_03769 7.5e-77 ctsR K Belongs to the CtsR family
IHFHMFKI_03770 8.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IHFHMFKI_03771 7.8e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IHFHMFKI_03772 4.5e-29 yazB K transcriptional
IHFHMFKI_03773 2.4e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IHFHMFKI_03774 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IHFHMFKI_03775 9.4e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IHFHMFKI_03776 5.5e-161 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
IHFHMFKI_03777 2.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
IHFHMFKI_03778 2.3e-270 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IHFHMFKI_03779 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IHFHMFKI_03780 3e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
IHFHMFKI_03781 2.4e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IHFHMFKI_03782 3.1e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IHFHMFKI_03783 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IHFHMFKI_03784 1.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IHFHMFKI_03785 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IHFHMFKI_03786 1.4e-184 KLT serine threonine protein kinase
IHFHMFKI_03787 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
IHFHMFKI_03788 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
IHFHMFKI_03791 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
IHFHMFKI_03792 4.1e-57 divIC D Septum formation initiator
IHFHMFKI_03793 8.4e-103 yabQ S spore cortex biosynthesis protein
IHFHMFKI_03794 1.9e-49 yabP S Sporulation protein YabP
IHFHMFKI_03795 2.8e-36 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
IHFHMFKI_03796 1.8e-273 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
IHFHMFKI_03797 1.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
IHFHMFKI_03798 6.2e-91 spoVT K stage V sporulation protein
IHFHMFKI_03799 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IHFHMFKI_03800 3.7e-40 yabK S Peptide ABC transporter permease
IHFHMFKI_03801 2.7e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IHFHMFKI_03802 3.8e-105 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IHFHMFKI_03803 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IHFHMFKI_03804 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IHFHMFKI_03805 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
IHFHMFKI_03806 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
IHFHMFKI_03807 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IHFHMFKI_03808 3.5e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IHFHMFKI_03809 2.9e-27 sspF S DNA topological change
IHFHMFKI_03810 7.8e-39 veg S protein conserved in bacteria
IHFHMFKI_03811 8.4e-146 yabG S peptidase
IHFHMFKI_03812 3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IHFHMFKI_03813 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IHFHMFKI_03814 7.7e-231 rpfB GH23 T protein conserved in bacteria
IHFHMFKI_03815 4.5e-143 tatD L hydrolase, TatD
IHFHMFKI_03816 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IHFHMFKI_03817 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
IHFHMFKI_03818 1.4e-161 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IHFHMFKI_03819 5.2e-47 yazA L endonuclease containing a URI domain
IHFHMFKI_03820 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
IHFHMFKI_03821 7.7e-37 yabA L Involved in initiation control of chromosome replication
IHFHMFKI_03822 8.8e-145 yaaT S stage 0 sporulation protein
IHFHMFKI_03823 1.3e-182 holB 2.7.7.7 L DNA polymerase III
IHFHMFKI_03824 1.2e-71 yaaR S protein conserved in bacteria
IHFHMFKI_03825 7.5e-55 yaaQ S protein conserved in bacteria
IHFHMFKI_03826 1.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IHFHMFKI_03827 2.9e-268 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
IHFHMFKI_03828 1.4e-188 yaaN P Belongs to the TelA family
IHFHMFKI_03829 3.3e-104 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
IHFHMFKI_03830 3.8e-30 csfB S Inhibitor of sigma-G Gin
IHFHMFKI_03831 4.2e-66 S Pfam:Phage_holin_4_1
IHFHMFKI_03834 6.7e-152 S Domain of unknown function (DUF2479)
IHFHMFKI_03835 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
IHFHMFKI_03836 2.2e-227 NU Prophage endopeptidase tail
IHFHMFKI_03837 1.6e-109 S Phage tail protein
IHFHMFKI_03838 0.0 S peptidoglycan catabolic process
IHFHMFKI_03839 1.5e-11
IHFHMFKI_03840 2e-23
IHFHMFKI_03841 4.9e-60
IHFHMFKI_03842 4.3e-30
IHFHMFKI_03843 6.7e-47 S Bacteriophage HK97-gp10, putative tail-component
IHFHMFKI_03844 4.7e-15 S Phage head-tail joining protein
IHFHMFKI_03845 3.2e-24 S Phage gp6-like head-tail connector protein
IHFHMFKI_03846 3e-37 S peptidoglycan catabolic process
IHFHMFKI_03848 2.7e-179 S capsid protein
IHFHMFKI_03849 9.7e-112 S peptidase activity
IHFHMFKI_03850 2.7e-238 S Phage portal protein
IHFHMFKI_03851 1.8e-10
IHFHMFKI_03852 7e-229 S Phage Terminase
IHFHMFKI_03853 1.1e-84 S Phage terminase, small subunit
IHFHMFKI_03855 1.1e-67 S HNH endonuclease
IHFHMFKI_03858 9e-09 ftsK D Ftsk_gamma
IHFHMFKI_03861 5.1e-28 L HNH endonuclease
IHFHMFKI_03862 1.5e-17
IHFHMFKI_03863 3.6e-148 S Phage Terminase
IHFHMFKI_03864 1.5e-110 S Phage portal protein
IHFHMFKI_03865 5.4e-48 S Caudovirus prohead serine protease
IHFHMFKI_03866 2.5e-90 S Phage capsid family
IHFHMFKI_03867 5e-12 S Phage gp6-like head-tail connector protein
IHFHMFKI_03868 2.2e-09 S Phage head-tail adaptor
IHFHMFKI_03869 9.5e-14 S TIGRFAM phage protein, HK97 gp10 family
IHFHMFKI_03870 1.5e-17
IHFHMFKI_03871 6.8e-52 S phage major tail protein, phi13 family
IHFHMFKI_03873 1.4e-140 D Phage-related minor tail protein
IHFHMFKI_03874 1e-39 S Phage tail protein
IHFHMFKI_03875 5.9e-104 mur1 NU Prophage endopeptidase tail
IHFHMFKI_03876 4.2e-286 M Pectate lyase superfamily protein
IHFHMFKI_03877 3.5e-137 S Domain of unknown function (DUF2479)
IHFHMFKI_03879 1.7e-09 S Phage uncharacterised protein (Phage_XkdX)
IHFHMFKI_03880 6.9e-61 S Pfam:Phage_holin_4_1
IHFHMFKI_03881 1.9e-37 bofA S Sigma-K factor-processing regulatory protein BofA
IHFHMFKI_03882 3.6e-32 yaaL S Protein of unknown function (DUF2508)
IHFHMFKI_03883 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IHFHMFKI_03884 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IHFHMFKI_03885 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IHFHMFKI_03886 1.7e-84 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IHFHMFKI_03887 1.6e-97 yaaI Q COG1335 Amidases related to nicotinamidase
IHFHMFKI_03888 1.7e-211 yaaH M Glycoside Hydrolase Family
IHFHMFKI_03889 6.1e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
IHFHMFKI_03890 4.5e-120 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
IHFHMFKI_03891 1.3e-09
IHFHMFKI_03892 6.6e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IHFHMFKI_03893 1.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IHFHMFKI_03894 2.8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
IHFHMFKI_03895 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
IHFHMFKI_03896 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IHFHMFKI_03897 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
IHFHMFKI_03898 5.3e-181 yaaC S YaaC-like Protein
IHFHMFKI_03899 1.6e-151 M1-574 T Transcriptional regulatory protein, C terminal
IHFHMFKI_03900 0.0 ywpD T PhoQ Sensor
IHFHMFKI_03901 6.8e-69 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_03902 1.5e-82 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_03903 5.3e-253 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IHFHMFKI_03904 3.4e-39 S COG NOG14552 non supervised orthologous group
IHFHMFKI_03907 1.6e-08
IHFHMFKI_03911 2.1e-53 L Phage integrase family
IHFHMFKI_03919 2e-08
IHFHMFKI_03924 1.6e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)