ORF_ID e_value Gene_name EC_number CAZy COGs Description
AFHCFNDA_00002 2.5e-195 S aspartate phosphatase
AFHCFNDA_00004 8e-175 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
AFHCFNDA_00005 1.3e-88 K Transcriptional regulator, TetR family
AFHCFNDA_00006 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
AFHCFNDA_00007 1.5e-116 3.2.1.8 G Glycosyl hydrolases family 11
AFHCFNDA_00008 1.8e-273 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
AFHCFNDA_00009 2.2e-254 xylA 5.3.1.5 G Belongs to the xylose isomerase family
AFHCFNDA_00010 9.6e-206 xylR GK ROK family
AFHCFNDA_00011 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
AFHCFNDA_00012 5.1e-246 xynT G MFS/sugar transport protein
AFHCFNDA_00013 8.6e-213 cypA C Cytochrome P450
AFHCFNDA_00014 1.3e-12
AFHCFNDA_00016 1.2e-260 glnA 6.3.1.2 E glutamine synthetase
AFHCFNDA_00017 8.8e-66 glnR K transcriptional
AFHCFNDA_00018 5e-240 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
AFHCFNDA_00019 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AFHCFNDA_00020 8.6e-176 spoVK O stage V sporulation protein K
AFHCFNDA_00021 1.2e-87 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFHCFNDA_00023 1.3e-103 ymaB S MutT family
AFHCFNDA_00024 2.6e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFHCFNDA_00025 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFHCFNDA_00026 2.3e-58 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
AFHCFNDA_00027 7.9e-21 ymzA
AFHCFNDA_00028 2.6e-40
AFHCFNDA_00029 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
AFHCFNDA_00030 6.7e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AFHCFNDA_00031 2.8e-43 ymaF S YmaF family
AFHCFNDA_00033 2.5e-47 ebrA P Small Multidrug Resistance protein
AFHCFNDA_00034 9.8e-53 ebrB P Small Multidrug Resistance protein
AFHCFNDA_00035 1.4e-75 ymaD O redox protein, regulator of disulfide bond formation
AFHCFNDA_00036 1e-117 ymaC S Replication protein
AFHCFNDA_00038 3.1e-248 aprX O Belongs to the peptidase S8 family
AFHCFNDA_00039 1.6e-61 ymzB
AFHCFNDA_00040 3.4e-116 yoaK S Membrane
AFHCFNDA_00041 5.2e-72 nucB M Deoxyribonuclease NucA/NucB
AFHCFNDA_00042 1.4e-223 cypA C Cytochrome P450
AFHCFNDA_00043 0.0 pks13 HQ Beta-ketoacyl synthase
AFHCFNDA_00044 0.0 dhbF IQ polyketide synthase
AFHCFNDA_00045 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
AFHCFNDA_00046 0.0 Q Polyketide synthase of type I
AFHCFNDA_00047 0.0 rhiB IQ polyketide synthase
AFHCFNDA_00048 6.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
AFHCFNDA_00049 8.8e-139 pksH 4.2.1.18 I enoyl-CoA hydratase
AFHCFNDA_00050 1.5e-241 pksG 2.3.3.10 I synthase
AFHCFNDA_00051 8.5e-35 acpK IQ Phosphopantetheine attachment site
AFHCFNDA_00052 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFHCFNDA_00053 6.9e-173 pksD Q Acyl transferase domain
AFHCFNDA_00054 8.6e-159 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFHCFNDA_00055 2.9e-125 pksB 3.1.2.6 S Polyketide biosynthesis
AFHCFNDA_00056 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AFHCFNDA_00057 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AFHCFNDA_00058 2.1e-86 cotE S Spore coat protein
AFHCFNDA_00059 1.2e-65 ymcA 3.6.3.21 S Belongs to the UPF0342 family
AFHCFNDA_00060 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AFHCFNDA_00061 7e-212 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
AFHCFNDA_00062 3.1e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
AFHCFNDA_00063 1.2e-36 spoVS S Stage V sporulation protein S
AFHCFNDA_00064 1.9e-152 ymdB S protein conserved in bacteria
AFHCFNDA_00065 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
AFHCFNDA_00066 2.4e-180 pbpX V Beta-lactamase
AFHCFNDA_00067 7.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AFHCFNDA_00068 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
AFHCFNDA_00069 4.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFHCFNDA_00070 1.4e-119 ymfM S protein conserved in bacteria
AFHCFNDA_00071 5.1e-142 ymfK S Protein of unknown function (DUF3388)
AFHCFNDA_00072 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
AFHCFNDA_00073 8.1e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
AFHCFNDA_00074 7.3e-239 ymfH S zinc protease
AFHCFNDA_00075 7e-234 ymfF S Peptidase M16
AFHCFNDA_00076 0.0 ydgH S drug exporters of the RND superfamily
AFHCFNDA_00077 5.8e-74 K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_00078 6.2e-225 ymfD EGP Major facilitator Superfamily
AFHCFNDA_00079 2e-129 ymfC K Transcriptional regulator
AFHCFNDA_00080 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
AFHCFNDA_00081 2.6e-29 S YlzJ-like protein
AFHCFNDA_00082 6.6e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
AFHCFNDA_00083 4.7e-302 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFHCFNDA_00084 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFHCFNDA_00085 2.2e-216 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
AFHCFNDA_00086 1.1e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AFHCFNDA_00087 3.9e-102 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
AFHCFNDA_00088 6.3e-157 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
AFHCFNDA_00089 2.6e-42 ymxH S YlmC YmxH family
AFHCFNDA_00090 8.3e-232 pepR S Belongs to the peptidase M16 family
AFHCFNDA_00091 7e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
AFHCFNDA_00092 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
AFHCFNDA_00093 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AFHCFNDA_00094 1.4e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
AFHCFNDA_00095 2.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AFHCFNDA_00096 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AFHCFNDA_00097 8.6e-44 ylxP S protein conserved in bacteria
AFHCFNDA_00098 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AFHCFNDA_00099 1.8e-47 ylxQ J ribosomal protein
AFHCFNDA_00100 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
AFHCFNDA_00101 3.5e-205 nusA K Participates in both transcription termination and antitermination
AFHCFNDA_00102 1.9e-80 rimP S Required for maturation of 30S ribosomal subunits
AFHCFNDA_00103 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFHCFNDA_00104 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
AFHCFNDA_00105 4.2e-231 rasP M zinc metalloprotease
AFHCFNDA_00106 2.3e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
AFHCFNDA_00107 8.4e-137 cdsA 2.7.7.41 S Belongs to the CDS family
AFHCFNDA_00108 1.3e-142 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFHCFNDA_00109 2.1e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
AFHCFNDA_00110 1.6e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
AFHCFNDA_00111 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AFHCFNDA_00112 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
AFHCFNDA_00113 1.7e-47 ylxL
AFHCFNDA_00114 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFHCFNDA_00115 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
AFHCFNDA_00116 7e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
AFHCFNDA_00117 2.5e-80 cheW NT COG0835 Chemotaxis signal transduction protein
AFHCFNDA_00118 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
AFHCFNDA_00119 4.9e-188 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
AFHCFNDA_00120 4.3e-153 flhG D Belongs to the ParA family
AFHCFNDA_00121 2.9e-156 flhF N Flagellar biosynthesis regulator FlhF
AFHCFNDA_00122 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AFHCFNDA_00123 2.5e-187 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AFHCFNDA_00124 9.2e-128 fliR N Flagellar biosynthetic protein FliR
AFHCFNDA_00125 7.5e-37 fliQ N Role in flagellar biosynthesis
AFHCFNDA_00126 3.7e-109 fliP N Plays a role in the flagellum-specific transport system
AFHCFNDA_00127 3.3e-110 fliZ N Flagellar biosynthesis protein, FliO
AFHCFNDA_00128 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
AFHCFNDA_00129 3.8e-175 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AFHCFNDA_00130 7.8e-180 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
AFHCFNDA_00131 5.1e-56 fliL N Controls the rotational direction of flagella during chemotaxis
AFHCFNDA_00132 5.4e-136 flgG N Flagellar basal body rod
AFHCFNDA_00133 2.7e-68 flgD N Flagellar basal body rod modification protein
AFHCFNDA_00134 5.5e-189 fliK N Flagellar hook-length control protein
AFHCFNDA_00135 1.2e-37 ylxF S MgtE intracellular N domain
AFHCFNDA_00136 4.5e-71 fliJ N Flagellar biosynthesis chaperone
AFHCFNDA_00137 2.7e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
AFHCFNDA_00138 1.4e-85 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
AFHCFNDA_00139 1.7e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
AFHCFNDA_00140 2.7e-251 fliF N The M ring may be actively involved in energy transduction
AFHCFNDA_00141 2.5e-31 fliE N Flagellar hook-basal body
AFHCFNDA_00142 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
AFHCFNDA_00143 7.8e-51 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
AFHCFNDA_00144 2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AFHCFNDA_00145 1.4e-230 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AFHCFNDA_00146 2.2e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AFHCFNDA_00147 3.3e-169 xerC L tyrosine recombinase XerC
AFHCFNDA_00148 5.3e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AFHCFNDA_00149 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFHCFNDA_00150 1.7e-162 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
AFHCFNDA_00151 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AFHCFNDA_00152 2.6e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
AFHCFNDA_00153 1.6e-42 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
AFHCFNDA_00154 1.4e-266 ylqG
AFHCFNDA_00155 5.5e-125 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFHCFNDA_00156 5.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AFHCFNDA_00157 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
AFHCFNDA_00158 4.3e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
AFHCFNDA_00159 1.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AFHCFNDA_00160 1.1e-60 ylqD S YlqD protein
AFHCFNDA_00161 1.7e-35 ylqC S Belongs to the UPF0109 family
AFHCFNDA_00162 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
AFHCFNDA_00163 9e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFHCFNDA_00164 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
AFHCFNDA_00165 5.9e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFHCFNDA_00166 0.0 smc D Required for chromosome condensation and partitioning
AFHCFNDA_00167 7.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
AFHCFNDA_00168 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
AFHCFNDA_00169 1.1e-127 IQ reductase
AFHCFNDA_00170 1.9e-167 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFHCFNDA_00171 2.3e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
AFHCFNDA_00172 2.2e-91 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
AFHCFNDA_00173 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFHCFNDA_00174 3.9e-154 sdaAA 4.3.1.17 E L-serine dehydratase
AFHCFNDA_00175 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
AFHCFNDA_00176 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
AFHCFNDA_00177 6.1e-58 asp S protein conserved in bacteria
AFHCFNDA_00178 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
AFHCFNDA_00179 1.8e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
AFHCFNDA_00180 2.2e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
AFHCFNDA_00181 3.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
AFHCFNDA_00182 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
AFHCFNDA_00183 7.1e-133 stp 3.1.3.16 T phosphatase
AFHCFNDA_00184 1.7e-204 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AFHCFNDA_00185 2.6e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AFHCFNDA_00186 2.4e-167 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AFHCFNDA_00187 2.5e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFHCFNDA_00188 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFHCFNDA_00189 3.5e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFHCFNDA_00190 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
AFHCFNDA_00191 8.9e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
AFHCFNDA_00192 1.5e-40 ylzA S Belongs to the UPF0296 family
AFHCFNDA_00193 2.3e-151 yloC S stress-induced protein
AFHCFNDA_00194 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
AFHCFNDA_00195 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
AFHCFNDA_00196 2.2e-266 amyA 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
AFHCFNDA_00197 4.3e-75 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
AFHCFNDA_00198 3.2e-136 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
AFHCFNDA_00199 1.4e-139 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
AFHCFNDA_00200 2.1e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
AFHCFNDA_00201 3.6e-221 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
AFHCFNDA_00202 8e-175 cysP P phosphate transporter
AFHCFNDA_00203 6.1e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
AFHCFNDA_00205 2.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFHCFNDA_00206 8.2e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
AFHCFNDA_00207 4.7e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
AFHCFNDA_00208 3.9e-139 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
AFHCFNDA_00209 0.0 carB 6.3.5.5 F Belongs to the CarB family
AFHCFNDA_00210 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AFHCFNDA_00211 2.2e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
AFHCFNDA_00212 1.7e-160 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
AFHCFNDA_00213 1.1e-229 pyrP F Xanthine uracil
AFHCFNDA_00214 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AFHCFNDA_00215 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFHCFNDA_00216 1.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AFHCFNDA_00217 3.8e-63 dksA T COG1734 DnaK suppressor protein
AFHCFNDA_00218 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFHCFNDA_00219 8.9e-68 divIVA D Cell division initiation protein
AFHCFNDA_00220 6.3e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
AFHCFNDA_00221 5.2e-41 yggT S membrane
AFHCFNDA_00222 5.7e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
AFHCFNDA_00223 4.1e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AFHCFNDA_00224 5.2e-153 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
AFHCFNDA_00225 2.2e-38 ylmC S sporulation protein
AFHCFNDA_00226 7e-242 argE 3.5.1.16 E Acetylornithine deacetylase
AFHCFNDA_00227 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
AFHCFNDA_00228 1.5e-138 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFHCFNDA_00229 1.2e-116 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFHCFNDA_00230 7.8e-158 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
AFHCFNDA_00231 0.0 bpr O COG1404 Subtilisin-like serine proteases
AFHCFNDA_00232 7.5e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFHCFNDA_00233 1.7e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
AFHCFNDA_00234 1.3e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
AFHCFNDA_00235 1.3e-165 murB 1.3.1.98 M cell wall formation
AFHCFNDA_00236 1.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AFHCFNDA_00237 2.2e-185 spoVE D Belongs to the SEDS family
AFHCFNDA_00238 6.7e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AFHCFNDA_00239 1.4e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AFHCFNDA_00240 1.1e-278 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AFHCFNDA_00241 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
AFHCFNDA_00242 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
AFHCFNDA_00243 2.4e-51 ftsL D Essential cell division protein
AFHCFNDA_00244 5.6e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
AFHCFNDA_00245 1.2e-77 mraZ K Belongs to the MraZ family
AFHCFNDA_00246 1.1e-300 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AFHCFNDA_00247 2.3e-149 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFHCFNDA_00248 5.8e-88 ylbP K n-acetyltransferase
AFHCFNDA_00249 5e-70 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
AFHCFNDA_00250 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
AFHCFNDA_00251 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
AFHCFNDA_00252 2.2e-220 ylbM S Belongs to the UPF0348 family
AFHCFNDA_00253 2.6e-183 ylbL T Belongs to the peptidase S16 family
AFHCFNDA_00254 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
AFHCFNDA_00255 3e-210 ylbJ S Sporulation integral membrane protein YlbJ
AFHCFNDA_00256 2.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AFHCFNDA_00257 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
AFHCFNDA_00258 1e-41 ylbG S UPF0298 protein
AFHCFNDA_00259 2.5e-69 ylbF S Belongs to the UPF0342 family
AFHCFNDA_00260 8.8e-37 ylbE S YlbE-like protein
AFHCFNDA_00261 1.5e-52 ylbD S Putative coat protein
AFHCFNDA_00262 9.2e-192 ylbC S protein with SCP PR1 domains
AFHCFNDA_00263 1.2e-71 ylbB T COG0517 FOG CBS domain
AFHCFNDA_00264 4.6e-58 ylbA S YugN-like family
AFHCFNDA_00265 1.9e-161 ctaG S cytochrome c oxidase
AFHCFNDA_00266 7.8e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
AFHCFNDA_00267 1.5e-109 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
AFHCFNDA_00268 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AFHCFNDA_00269 1.2e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
AFHCFNDA_00270 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
AFHCFNDA_00271 2.5e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
AFHCFNDA_00272 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AFHCFNDA_00273 2e-209 ftsW D Belongs to the SEDS family
AFHCFNDA_00274 8.7e-44 ylaN S Belongs to the UPF0358 family
AFHCFNDA_00275 2e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
AFHCFNDA_00276 2.2e-79 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AFHCFNDA_00277 7.8e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
AFHCFNDA_00278 6.1e-98 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFHCFNDA_00279 1.5e-32 ylaI S protein conserved in bacteria
AFHCFNDA_00280 6.6e-48 ylaH S YlaH-like protein
AFHCFNDA_00281 0.0 typA T GTP-binding protein TypA
AFHCFNDA_00282 6.7e-24 S Family of unknown function (DUF5325)
AFHCFNDA_00283 2e-37 ylaE
AFHCFNDA_00284 1.7e-13 sigC S Putative zinc-finger
AFHCFNDA_00285 5.6e-26 ylaA
AFHCFNDA_00286 3e-287 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
AFHCFNDA_00287 1.6e-70 ykzC S Acetyltransferase (GNAT) family
AFHCFNDA_00288 5.1e-150 suhB 3.1.3.25 G Inositol monophosphatase
AFHCFNDA_00289 6.3e-24 ykzI
AFHCFNDA_00290 3.5e-117 yktB S Belongs to the UPF0637 family
AFHCFNDA_00291 5.9e-42 yktA S Belongs to the UPF0223 family
AFHCFNDA_00292 5.2e-273 speA 4.1.1.19 E Arginine
AFHCFNDA_00293 1.4e-126 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
AFHCFNDA_00294 6.1e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
AFHCFNDA_00295 2.7e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFHCFNDA_00296 2.1e-225 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFHCFNDA_00297 1.2e-177 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFHCFNDA_00298 3.8e-183 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFHCFNDA_00299 3e-66 recN L Putative cell-wall binding lipoprotein
AFHCFNDA_00301 1.6e-97 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
AFHCFNDA_00302 2.5e-141 ykrA S hydrolases of the HAD superfamily
AFHCFNDA_00303 5.3e-30 ykzG S Belongs to the UPF0356 family
AFHCFNDA_00304 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AFHCFNDA_00305 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AFHCFNDA_00306 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
AFHCFNDA_00307 1.6e-146 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
AFHCFNDA_00308 9.1e-237 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
AFHCFNDA_00309 1e-44 abrB K of stationary sporulation gene expression
AFHCFNDA_00310 7.7e-183 mreB D Rod-share determining protein MreBH
AFHCFNDA_00311 1.1e-12 S Uncharacterized protein YkpC
AFHCFNDA_00312 9.5e-236 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
AFHCFNDA_00313 1.3e-157 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFHCFNDA_00314 5.5e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFHCFNDA_00315 6.4e-36 ykoA
AFHCFNDA_00316 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
AFHCFNDA_00317 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
AFHCFNDA_00318 7.1e-164 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
AFHCFNDA_00319 4.3e-130 fruR K Transcriptional regulator
AFHCFNDA_00320 4e-207 yknZ V ABC transporter (permease)
AFHCFNDA_00321 5.1e-122 macB V ABC transporter, ATP-binding protein
AFHCFNDA_00322 9.9e-155 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AFHCFNDA_00323 7.3e-100 yknW S Yip1 domain
AFHCFNDA_00324 4.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AFHCFNDA_00325 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
AFHCFNDA_00326 1.7e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
AFHCFNDA_00327 1.5e-239 moeA 2.10.1.1 H molybdopterin
AFHCFNDA_00328 4.1e-184 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AFHCFNDA_00329 2.2e-100 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
AFHCFNDA_00330 3.3e-146 yknT
AFHCFNDA_00331 3.8e-97 rok K Repressor of ComK
AFHCFNDA_00333 5.5e-72 ykuV CO thiol-disulfide
AFHCFNDA_00335 1.6e-138 ykuT M Mechanosensitive ion channel
AFHCFNDA_00336 1.8e-37 ykuS S Belongs to the UPF0180 family
AFHCFNDA_00337 6.7e-212 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
AFHCFNDA_00338 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
AFHCFNDA_00339 1.3e-73 fld C Flavodoxin
AFHCFNDA_00340 8.6e-162 ykuO
AFHCFNDA_00341 2.4e-86 fld C Flavodoxin
AFHCFNDA_00342 2.3e-167 ccpC K Transcriptional regulator
AFHCFNDA_00343 1e-75 ykuL S CBS domain
AFHCFNDA_00344 7.3e-26 ykzF S Antirepressor AbbA
AFHCFNDA_00345 1.7e-90 ykuK S Ribonuclease H-like
AFHCFNDA_00346 2e-36 ykuJ S protein conserved in bacteria
AFHCFNDA_00347 2.4e-231 ykuI T Diguanylate phosphodiesterase
AFHCFNDA_00349 1.6e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_00350 7.5e-147 ykuE S Metallophosphoesterase
AFHCFNDA_00351 5.1e-87 ykuD S protein conserved in bacteria
AFHCFNDA_00352 3.8e-235 ykuC EGP Major facilitator Superfamily
AFHCFNDA_00353 3.2e-83 ykyB S YkyB-like protein
AFHCFNDA_00354 2.2e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
AFHCFNDA_00355 1.4e-09
AFHCFNDA_00356 5.7e-214 patA 2.6.1.1 E Aminotransferase
AFHCFNDA_00357 5.4e-288 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
AFHCFNDA_00358 1.6e-260 mrdA 3.4.16.4 M Penicillin-binding Protein
AFHCFNDA_00359 5.7e-127 mrdA 3.4.16.4 M Penicillin-binding Protein
AFHCFNDA_00360 2.2e-113 ykwD J protein with SCP PR1 domains
AFHCFNDA_00361 1.6e-48
AFHCFNDA_00362 2.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
AFHCFNDA_00363 3.1e-255 mcpC NT chemotaxis protein
AFHCFNDA_00364 1.8e-192 splB 4.1.99.14 L Spore photoproduct lyase
AFHCFNDA_00365 6.7e-37 splA S Transcriptional regulator
AFHCFNDA_00366 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFHCFNDA_00367 2.1e-39 ptsH G phosphocarrier protein HPr
AFHCFNDA_00368 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFHCFNDA_00369 8.1e-154 glcT K antiterminator
AFHCFNDA_00370 1.9e-170 ykvZ 5.1.1.1 K Transcriptional regulator
AFHCFNDA_00371 5e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
AFHCFNDA_00372 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
AFHCFNDA_00373 8.3e-82 stoA CO thiol-disulfide
AFHCFNDA_00374 2.7e-236 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFHCFNDA_00375 1.1e-104 ykvT 3.5.1.28 M Cell Wall Hydrolase
AFHCFNDA_00376 2.3e-27
AFHCFNDA_00377 1.7e-24 ykvS S protein conserved in bacteria
AFHCFNDA_00378 1.8e-41 ykvR S Protein of unknown function (DUF3219)
AFHCFNDA_00379 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AFHCFNDA_00380 7.8e-137 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
AFHCFNDA_00381 2.9e-78 queD 4.1.2.50, 4.2.3.12 H synthase
AFHCFNDA_00382 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AFHCFNDA_00383 9.3e-146
AFHCFNDA_00384 4.9e-13
AFHCFNDA_00385 6.4e-177 ykvI S membrane
AFHCFNDA_00386 0.0 clpE O Belongs to the ClpA ClpB family
AFHCFNDA_00387 2.5e-136 motA N flagellar motor
AFHCFNDA_00388 1.7e-121 motB N Flagellar motor protein
AFHCFNDA_00389 3.2e-77 ykvE K transcriptional
AFHCFNDA_00390 1e-268 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
AFHCFNDA_00391 4e-11 S Spo0E like sporulation regulatory protein
AFHCFNDA_00392 3.6e-91 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
AFHCFNDA_00393 1.2e-109 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
AFHCFNDA_00394 1.6e-131 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
AFHCFNDA_00395 6.9e-223 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
AFHCFNDA_00396 5.2e-223 mtnE 2.6.1.83 E Aminotransferase
AFHCFNDA_00397 7.3e-138 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AFHCFNDA_00398 1.6e-219 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
AFHCFNDA_00399 1e-190 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AFHCFNDA_00401 5.4e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFHCFNDA_00402 0.0 kinE 2.7.13.3 T Histidine kinase
AFHCFNDA_00403 3.8e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
AFHCFNDA_00404 1.2e-19 ykzE
AFHCFNDA_00405 3e-111 ydfR S Protein of unknown function (DUF421)
AFHCFNDA_00406 6.1e-236 ktrB P COG0168 Trk-type K transport systems, membrane components
AFHCFNDA_00407 3.9e-154 htpX O Belongs to the peptidase M48B family
AFHCFNDA_00408 9.5e-124 ykrK S Domain of unknown function (DUF1836)
AFHCFNDA_00409 9.6e-26 sspD S small acid-soluble spore protein
AFHCFNDA_00410 4.5e-118 rsgI S Anti-sigma factor N-terminus
AFHCFNDA_00411 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFHCFNDA_00412 5.4e-128 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
AFHCFNDA_00413 4.4e-95 ykoX S membrane-associated protein
AFHCFNDA_00414 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
AFHCFNDA_00415 2.8e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AFHCFNDA_00416 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
AFHCFNDA_00417 4.6e-97 ykoP G polysaccharide deacetylase
AFHCFNDA_00418 1.5e-80 ykoM K transcriptional
AFHCFNDA_00419 5.9e-25 ykoL
AFHCFNDA_00420 1.9e-16
AFHCFNDA_00421 1.6e-52 tnrA K transcriptional
AFHCFNDA_00422 3e-235 mgtE P Acts as a magnesium transporter
AFHCFNDA_00424 1.6e-238 ydhD M Glycosyl hydrolase
AFHCFNDA_00425 9.3e-96 ykoE S ABC-type cobalt transport system, permease component
AFHCFNDA_00426 8.6e-277 P ABC transporter, ATP-binding protein
AFHCFNDA_00427 7.1e-125 ykoC P Cobalt transport protein
AFHCFNDA_00428 7.8e-141 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFHCFNDA_00429 6.8e-173 isp O Belongs to the peptidase S8 family
AFHCFNDA_00430 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AFHCFNDA_00431 9.9e-118 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
AFHCFNDA_00432 4e-207 hcaT 1.5.1.2 EGP Major facilitator Superfamily
AFHCFNDA_00433 9.3e-94 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
AFHCFNDA_00434 6e-205 M Glycosyl transferase family 2
AFHCFNDA_00436 2.9e-51 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AFHCFNDA_00437 7.9e-70 ohrB O Organic hydroperoxide resistance protein
AFHCFNDA_00438 7.5e-78 ohrR K COG1846 Transcriptional regulators
AFHCFNDA_00439 4.1e-69 ohrA O Organic hydroperoxide resistance protein
AFHCFNDA_00440 9.6e-220 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AFHCFNDA_00441 4.4e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFHCFNDA_00442 4.4e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
AFHCFNDA_00443 1e-48 ykkD P Multidrug resistance protein
AFHCFNDA_00444 1.2e-48 ykkC P Multidrug resistance protein
AFHCFNDA_00445 4.4e-92 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AFHCFNDA_00446 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
AFHCFNDA_00447 1.5e-131 ykgA E Amidinotransferase
AFHCFNDA_00448 4.2e-200 pgl 3.1.1.31 G 6-phosphogluconolactonase
AFHCFNDA_00449 3e-50 ykfD E Belongs to the ABC transporter superfamily
AFHCFNDA_00450 4.7e-68 ykfD E Belongs to the ABC transporter superfamily
AFHCFNDA_00451 2.4e-156 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
AFHCFNDA_00452 1.1e-190 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
AFHCFNDA_00453 1.9e-172 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
AFHCFNDA_00454 1.3e-309 dppE E ABC transporter substrate-binding protein
AFHCFNDA_00455 3e-182 dppD P Belongs to the ABC transporter superfamily
AFHCFNDA_00456 5.3e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFHCFNDA_00457 3.5e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFHCFNDA_00458 3.6e-154 dppA E D-aminopeptidase
AFHCFNDA_00459 2.3e-263 yubD P Major Facilitator Superfamily
AFHCFNDA_00460 5e-198 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFHCFNDA_00462 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFHCFNDA_00463 5.2e-298 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AFHCFNDA_00464 5.3e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
AFHCFNDA_00465 5.2e-240 steT E amino acid
AFHCFNDA_00466 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
AFHCFNDA_00467 2.4e-173 pit P phosphate transporter
AFHCFNDA_00468 1.7e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
AFHCFNDA_00469 8.7e-23 spoIISB S Stage II sporulation protein SB
AFHCFNDA_00470 7.6e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFHCFNDA_00471 4.3e-37 xhlB S SPP1 phage holin
AFHCFNDA_00472 7.4e-37 xhlA S Haemolysin XhlA
AFHCFNDA_00473 2.5e-130 xepA
AFHCFNDA_00474 6.8e-27 xkdX
AFHCFNDA_00476 2.1e-160
AFHCFNDA_00477 6.1e-26
AFHCFNDA_00478 4.2e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
AFHCFNDA_00479 1.5e-162 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
AFHCFNDA_00480 2.7e-57 xkdS S Protein of unknown function (DUF2634)
AFHCFNDA_00481 8.5e-33 xkdR S Protein of unknown function (DUF2577)
AFHCFNDA_00482 2.9e-163 xkdQ 3.2.1.96 G NLP P60 protein
AFHCFNDA_00483 8.5e-100 xkdP S Lysin motif
AFHCFNDA_00484 4.1e-180 xkdO L Transglycosylase SLT domain
AFHCFNDA_00485 3.4e-19
AFHCFNDA_00486 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
AFHCFNDA_00487 2e-74 xkdM S Phage tail tube protein
AFHCFNDA_00488 2.1e-223 xkdK S Phage tail sheath C-terminal domain
AFHCFNDA_00489 1.4e-14
AFHCFNDA_00490 5.8e-58 xkdJ
AFHCFNDA_00491 4.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
AFHCFNDA_00492 3.3e-40 yqbH S Domain of unknown function (DUF3599)
AFHCFNDA_00493 1.3e-45 yqbG S Protein of unknown function (DUF3199)
AFHCFNDA_00494 3e-157 xkdG S Phage capsid family
AFHCFNDA_00495 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
AFHCFNDA_00496 7.4e-240 yqbA S portal protein
AFHCFNDA_00497 1.6e-209 xtmB S phage terminase, large subunit
AFHCFNDA_00498 1.5e-109 xtmA L phage terminase small subunit
AFHCFNDA_00499 8.5e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
AFHCFNDA_00500 4.5e-10 yqaO S Phage-like element PBSX protein XtrA
AFHCFNDA_00503 3.2e-144 xkdC L Bacterial dnaA protein
AFHCFNDA_00505 2.6e-55 xre K Helix-turn-helix XRE-family like proteins
AFHCFNDA_00506 1.5e-106 xkdA E IrrE N-terminal-like domain
AFHCFNDA_00507 4.8e-100 yjqB S phage-related replication protein
AFHCFNDA_00508 6.8e-60 yjqA S Bacterial PH domain
AFHCFNDA_00509 2.3e-97 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AFHCFNDA_00510 1.1e-46 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AFHCFNDA_00512 6e-185 S response regulator aspartate phosphatase
AFHCFNDA_00513 2e-17 S response regulator aspartate phosphatase
AFHCFNDA_00514 4.9e-76 yjoA S DinB family
AFHCFNDA_00515 6.9e-128 MA20_18170 S membrane transporter protein
AFHCFNDA_00517 1.9e-128 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
AFHCFNDA_00518 5.2e-87 T Transcriptional regulatory protein, C terminal
AFHCFNDA_00519 9.7e-161 uxaA 4.2.1.7, 4.4.1.24 G Altronate
AFHCFNDA_00520 5.4e-181 exuR K transcriptional
AFHCFNDA_00521 2e-65 uxaC 5.3.1.12 G glucuronate isomerase
AFHCFNDA_00522 3.2e-217 yjlD 1.6.99.3 C NADH dehydrogenase
AFHCFNDA_00523 7e-66 yjlC S Protein of unknown function (DUF1641)
AFHCFNDA_00524 7.3e-86 yjlB S Cupin domain
AFHCFNDA_00525 5.9e-172 yjlA EG Putative multidrug resistance efflux transporter
AFHCFNDA_00526 2.4e-125 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
AFHCFNDA_00527 2.2e-118 ybbM S transport system, permease component
AFHCFNDA_00528 4.7e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
AFHCFNDA_00529 6.8e-29
AFHCFNDA_00530 1.8e-215 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
AFHCFNDA_00531 2e-214 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
AFHCFNDA_00532 9.4e-87 yjgD S Protein of unknown function (DUF1641)
AFHCFNDA_00533 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
AFHCFNDA_00535 6.5e-75 yjgB S Domain of unknown function (DUF4309)
AFHCFNDA_00536 5.9e-62 T PhoQ Sensor
AFHCFNDA_00537 5.4e-20 yjfB S Putative motility protein
AFHCFNDA_00539 2.2e-103 yhiD S MgtC SapB transporter
AFHCFNDA_00540 4.5e-52 K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_00541 7.6e-34
AFHCFNDA_00542 5.8e-118 5.4.2.6 S Haloacid dehalogenase-like hydrolase
AFHCFNDA_00543 3.7e-137 lacR K COG1349 Transcriptional regulators of sugar metabolism
AFHCFNDA_00544 1.6e-279 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
AFHCFNDA_00545 3.4e-49 lacF 2.7.1.207 G phosphotransferase system
AFHCFNDA_00546 4.6e-228 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFHCFNDA_00547 5.8e-52 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFHCFNDA_00548 1.8e-217 ganA 3.2.1.89 G arabinogalactan
AFHCFNDA_00549 2.2e-76 napB K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_00550 3e-238 yfjF EGP Belongs to the major facilitator superfamily
AFHCFNDA_00551 3e-44 yjcS S Antibiotic biosynthesis monooxygenase
AFHCFNDA_00552 2e-153 bla 3.5.2.6 V beta-lactamase
AFHCFNDA_00554 1.5e-16 N Kelch motif
AFHCFNDA_00559 2.2e-28 S Bacillus cereus group antimicrobial protein
AFHCFNDA_00560 1.8e-193 ytvI S sporulation integral membrane protein YtvI
AFHCFNDA_00561 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
AFHCFNDA_00562 1.2e-292 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
AFHCFNDA_00563 9.8e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
AFHCFNDA_00564 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
AFHCFNDA_00565 6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AFHCFNDA_00566 5.9e-222 ytsJ 1.1.1.38 C Malate dehydrogenase
AFHCFNDA_00567 0.0 dnaE 2.7.7.7 L DNA polymerase
AFHCFNDA_00568 3.9e-54 ytrH S Sporulation protein YtrH
AFHCFNDA_00569 5.6e-86 ytrI
AFHCFNDA_00570 6.4e-22
AFHCFNDA_00571 2.9e-176 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
AFHCFNDA_00572 3.8e-45 ytpI S YtpI-like protein
AFHCFNDA_00573 6.8e-238 ytoI K transcriptional regulator containing CBS domains
AFHCFNDA_00574 1.1e-127 ytkL S Belongs to the UPF0173 family
AFHCFNDA_00575 3.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_00577 6.1e-260 argH 4.3.2.1 E argininosuccinate lyase
AFHCFNDA_00578 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
AFHCFNDA_00579 8e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
AFHCFNDA_00580 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AFHCFNDA_00581 9.7e-175 ytxK 2.1.1.72 L DNA methylase
AFHCFNDA_00582 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AFHCFNDA_00583 1.5e-63 ytfJ S Sporulation protein YtfJ
AFHCFNDA_00584 4.1e-111 ytfI S Protein of unknown function (DUF2953)
AFHCFNDA_00585 4.5e-80 yteJ S RDD family
AFHCFNDA_00586 1.4e-176 sppA OU signal peptide peptidase SppA
AFHCFNDA_00587 5.9e-149 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFHCFNDA_00588 8.3e-301 ytcJ S amidohydrolase
AFHCFNDA_00589 9.1e-300 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
AFHCFNDA_00590 6.6e-31 sspB S spore protein
AFHCFNDA_00591 1.4e-220 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFHCFNDA_00592 3.4e-203 iscS2 2.8.1.7 E Cysteine desulfurase
AFHCFNDA_00593 6.4e-238 braB E Component of the transport system for branched-chain amino acids
AFHCFNDA_00594 4e-261 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AFHCFNDA_00595 4.3e-144 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
AFHCFNDA_00596 7.9e-106 yttP K Transcriptional regulator
AFHCFNDA_00597 8.6e-84 ytsP 1.8.4.14 T GAF domain-containing protein
AFHCFNDA_00598 4.6e-268 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
AFHCFNDA_00599 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFHCFNDA_00600 5.8e-214 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFHCFNDA_00603 1.3e-08 yhbO 1.11.1.6, 3.5.1.124 S protease
AFHCFNDA_00605 2.9e-126 E GDSL-like Lipase/Acylhydrolase family
AFHCFNDA_00606 5.8e-147 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFHCFNDA_00607 3.5e-146 K Transcriptional regulator
AFHCFNDA_00608 1.9e-119 azlC E AzlC protein
AFHCFNDA_00609 7.4e-47 azlD S Branched-chain amino acid transport protein (AzlD)
AFHCFNDA_00610 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFHCFNDA_00611 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
AFHCFNDA_00612 7.5e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
AFHCFNDA_00613 2e-107 acuB S Domain in cystathionine beta-synthase and other proteins.
AFHCFNDA_00614 7.9e-224 acuC BQ histone deacetylase
AFHCFNDA_00615 2.7e-98 motS N Flagellar motor protein
AFHCFNDA_00616 4.8e-143 motA N flagellar motor
AFHCFNDA_00617 3.9e-179 ccpA K catabolite control protein A
AFHCFNDA_00618 1.6e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
AFHCFNDA_00619 2.2e-43 ytxJ O Protein of unknown function (DUF2847)
AFHCFNDA_00620 1.7e-16 ytxH S COG4980 Gas vesicle protein
AFHCFNDA_00621 1.1e-13 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AFHCFNDA_00622 7.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
AFHCFNDA_00623 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
AFHCFNDA_00624 5.9e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFHCFNDA_00625 3e-145 ytpQ S Belongs to the UPF0354 family
AFHCFNDA_00626 3.5e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AFHCFNDA_00627 1.8e-75 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
AFHCFNDA_00628 4.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
AFHCFNDA_00629 1.7e-51 ytzB S small secreted protein
AFHCFNDA_00630 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
AFHCFNDA_00631 3.4e-160 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
AFHCFNDA_00632 1.5e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
AFHCFNDA_00633 1.3e-44 ytzH S YtzH-like protein
AFHCFNDA_00634 4.1e-155 ytmP 2.7.1.89 M Phosphotransferase
AFHCFNDA_00635 2.6e-169 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
AFHCFNDA_00636 5.1e-141 ytlQ
AFHCFNDA_00637 2.4e-98 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AFHCFNDA_00638 1.6e-166 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFHCFNDA_00639 6.2e-260 pepV 3.5.1.18 E Dipeptidase
AFHCFNDA_00640 5.5e-226 pbuO S permease
AFHCFNDA_00641 1.5e-198 ythQ U Bacterial ABC transporter protein EcsB
AFHCFNDA_00642 1.9e-116 ythP V ABC transporter
AFHCFNDA_00643 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
AFHCFNDA_00644 2e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFHCFNDA_00645 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFHCFNDA_00646 5.5e-231 ytfP S HI0933-like protein
AFHCFNDA_00647 1.4e-276 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
AFHCFNDA_00648 2.6e-25 yteV S Sporulation protein Cse60
AFHCFNDA_00649 7.2e-181 msmR K Transcriptional regulator
AFHCFNDA_00650 4.1e-234 msmE G Bacterial extracellular solute-binding protein
AFHCFNDA_00651 3.3e-144 amyD G Binding-protein-dependent transport system inner membrane component
AFHCFNDA_00652 1.3e-245 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
AFHCFNDA_00653 1.1e-73 M Acetyltransferase (GNAT) domain
AFHCFNDA_00654 1.3e-51 ytwF P Sulfurtransferase
AFHCFNDA_00655 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFHCFNDA_00656 1.2e-52 ytvB S Protein of unknown function (DUF4257)
AFHCFNDA_00657 3e-134 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
AFHCFNDA_00658 4.9e-205 yttB EGP Major facilitator Superfamily
AFHCFNDA_00659 4e-102 ywaF S Integral membrane protein
AFHCFNDA_00660 0.0 bceB V ABC transporter (permease)
AFHCFNDA_00661 2.7e-132 bceA V ABC transporter, ATP-binding protein
AFHCFNDA_00662 5.4e-154 T PhoQ Sensor
AFHCFNDA_00663 1.1e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_00664 5.8e-199 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
AFHCFNDA_00665 1.1e-124 ytrE V ABC transporter, ATP-binding protein
AFHCFNDA_00666 1.1e-144
AFHCFNDA_00667 7.8e-148 P ABC-2 family transporter protein
AFHCFNDA_00668 1.9e-162 S ABC-2 family transporter protein
AFHCFNDA_00669 1.4e-156 ytrB P abc transporter atp-binding protein
AFHCFNDA_00670 4.3e-65 ytrA K GntR family transcriptional regulator
AFHCFNDA_00672 8.1e-39 ytzC S Protein of unknown function (DUF2524)
AFHCFNDA_00673 1.4e-189 yhcC S Fe-S oxidoreductase
AFHCFNDA_00674 3.4e-103 ytqB J Putative rRNA methylase
AFHCFNDA_00676 7.3e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
AFHCFNDA_00677 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
AFHCFNDA_00678 9e-55 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AFHCFNDA_00679 8.5e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
AFHCFNDA_00680 0.0 asnB 6.3.5.4 E Asparagine synthase
AFHCFNDA_00681 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AFHCFNDA_00682 3e-303 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AFHCFNDA_00683 8e-38 ytmB S Protein of unknown function (DUF2584)
AFHCFNDA_00684 2.2e-145 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
AFHCFNDA_00685 1.9e-178 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
AFHCFNDA_00686 1.5e-141 ytlC P ABC transporter
AFHCFNDA_00687 3.8e-124 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
AFHCFNDA_00688 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
AFHCFNDA_00689 1.2e-59 ytkC S Bacteriophage holin family
AFHCFNDA_00690 7.8e-76 dps P Belongs to the Dps family
AFHCFNDA_00692 4.4e-74 ytkA S YtkA-like
AFHCFNDA_00693 2.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
AFHCFNDA_00694 2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
AFHCFNDA_00695 1.3e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
AFHCFNDA_00696 7.9e-41 rpmE2 J Ribosomal protein L31
AFHCFNDA_00697 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
AFHCFNDA_00698 1.2e-183 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
AFHCFNDA_00699 4e-24 S Domain of Unknown Function (DUF1540)
AFHCFNDA_00700 2e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
AFHCFNDA_00701 1.7e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
AFHCFNDA_00702 7.9e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AFHCFNDA_00703 1.9e-147 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
AFHCFNDA_00704 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AFHCFNDA_00705 3.7e-260 menF 5.4.4.2 HQ Isochorismate synthase
AFHCFNDA_00706 2.3e-125 dksA T COG1734 DnaK suppressor protein
AFHCFNDA_00707 4.8e-71 tspO T membrane
AFHCFNDA_00708 2.2e-114 M1-574 T Transcriptional regulatory protein, C terminal
AFHCFNDA_00709 6e-28 M1-574 T Transcriptional regulatory protein, C terminal
AFHCFNDA_00710 0.0 ywpD T PhoQ Sensor
AFHCFNDA_00711 7.7e-76 M1-820 Q Collagen triple helix repeat (20 copies)
AFHCFNDA_00712 1.2e-19 Q calcium- and calmodulin-responsive adenylate cyclase activity
AFHCFNDA_00714 3.7e-26 Q PFAM Collagen triple helix
AFHCFNDA_00715 1e-233 yflS P Sodium:sulfate symporter transmembrane region
AFHCFNDA_00716 2e-233 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
AFHCFNDA_00717 1.3e-57 yflT S Heat induced stress protein YflT
AFHCFNDA_00718 4.1e-25 S Protein of unknown function (DUF3212)
AFHCFNDA_00719 5.7e-79 yfmJ S N-terminal domain of oxidoreductase
AFHCFNDA_00720 3.7e-51 yfmJ S N-terminal domain of oxidoreductase
AFHCFNDA_00721 4.3e-203 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
AFHCFNDA_00722 4.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFHCFNDA_00723 3.2e-196 yfmO EGP Major facilitator Superfamily
AFHCFNDA_00724 5.8e-68 yfmP K transcriptional
AFHCFNDA_00725 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
AFHCFNDA_00726 6.5e-201 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFHCFNDA_00727 6.4e-165 IQ Enoyl-(Acyl carrier protein) reductase
AFHCFNDA_00728 1.1e-105 yfmS NT chemotaxis protein
AFHCFNDA_00729 6.1e-274 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFHCFNDA_00730 7.6e-242 yfnA E amino acid
AFHCFNDA_00731 1e-213 fsr P COG0477 Permeases of the major facilitator superfamily
AFHCFNDA_00732 4.5e-177 yfnD M Nucleotide-diphospho-sugar transferase
AFHCFNDA_00733 1.6e-213 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
AFHCFNDA_00734 8.4e-173 yfnF M Nucleotide-diphospho-sugar transferase
AFHCFNDA_00735 9.2e-172 yfnG 4.2.1.45 M dehydratase
AFHCFNDA_00736 4.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
AFHCFNDA_00737 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AFHCFNDA_00739 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
AFHCFNDA_00740 1.7e-196 yetN S Protein of unknown function (DUF3900)
AFHCFNDA_00741 8.1e-194 yetM CH FAD binding domain
AFHCFNDA_00742 4.9e-85 yetL K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_00743 2e-104 yetJ S Belongs to the BI1 family
AFHCFNDA_00744 2.4e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
AFHCFNDA_00745 1.4e-20 yezD S Uncharacterized small protein (DUF2292)
AFHCFNDA_00746 3.7e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFHCFNDA_00747 7e-62 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFHCFNDA_00748 7e-53 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
AFHCFNDA_00749 3e-114 yetF S membrane
AFHCFNDA_00751 2.2e-88 yesJ K Acetyltransferase (GNAT) family
AFHCFNDA_00752 2e-103 cotJC P Spore Coat
AFHCFNDA_00753 1.3e-44 cotJB S CotJB protein
AFHCFNDA_00754 9.1e-45 cotJA S Spore coat associated protein JA (CotJA)
AFHCFNDA_00755 1.7e-109 aadK G Streptomycin adenylyltransferase
AFHCFNDA_00757 1.2e-126 yeeN K transcriptional regulatory protein
AFHCFNDA_00758 1.3e-120 yobL L Belongs to the WXG100 family
AFHCFNDA_00759 7.8e-198 yobL L nucleic acid phosphodiester bond hydrolysis
AFHCFNDA_00760 1.9e-51 S Protein of unknown function, DUF600
AFHCFNDA_00761 1.5e-56 S Protein of unknown function, DUF600
AFHCFNDA_00762 2e-38 S Protein of unknown function, DUF600
AFHCFNDA_00763 1.4e-137 cylB V ABC-2 type transporter
AFHCFNDA_00764 8.5e-160 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
AFHCFNDA_00765 1.9e-310 L Uncharacterized conserved protein (DUF2075)
AFHCFNDA_00766 1.6e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFHCFNDA_00767 7.4e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AFHCFNDA_00768 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AFHCFNDA_00769 1.1e-147 yerO K Transcriptional regulator
AFHCFNDA_00770 1.5e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFHCFNDA_00771 2e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
AFHCFNDA_00772 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFHCFNDA_00773 4.9e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFHCFNDA_00774 3.1e-119 sapB S MgtC SapB transporter
AFHCFNDA_00775 5.4e-181 yerI S homoserine kinase type II (protein kinase fold)
AFHCFNDA_00776 5.2e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
AFHCFNDA_00777 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AFHCFNDA_00778 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
AFHCFNDA_00779 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AFHCFNDA_00780 6.1e-296 yerD 1.4.7.1 E Belongs to the glutamate synthase family
AFHCFNDA_00781 2.4e-50 yerC S protein conserved in bacteria
AFHCFNDA_00782 2.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
AFHCFNDA_00783 0.0 yerA 3.5.4.2 F adenine deaminase
AFHCFNDA_00784 5.4e-25 S Protein of unknown function (DUF2892)
AFHCFNDA_00785 4.2e-135 yjeH E Amino acid permease
AFHCFNDA_00786 3.8e-62 K helix_turn_helix ASNC type
AFHCFNDA_00787 4.7e-230 purD 6.3.4.13 F Belongs to the GARS family
AFHCFNDA_00788 7.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
AFHCFNDA_00789 5.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AFHCFNDA_00790 8.7e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
AFHCFNDA_00791 1.3e-268 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AFHCFNDA_00792 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFHCFNDA_00793 1.2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFHCFNDA_00794 4.2e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFHCFNDA_00795 3.6e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
AFHCFNDA_00796 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFHCFNDA_00797 7.7e-219 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AFHCFNDA_00798 2.2e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AFHCFNDA_00799 9.5e-29 yebG S NETI protein
AFHCFNDA_00800 1.5e-92 yebE S UPF0316 protein
AFHCFNDA_00802 2.4e-123 yebC M Membrane
AFHCFNDA_00803 8.1e-209 pbuG S permease
AFHCFNDA_00804 2.3e-249 S Domain of unknown function (DUF4179)
AFHCFNDA_00805 1.5e-89 sigV K Belongs to the sigma-70 factor family. ECF subfamily
AFHCFNDA_00806 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
AFHCFNDA_00807 0.0 yebA E COG1305 Transglutaminase-like enzymes
AFHCFNDA_00808 1.2e-198 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
AFHCFNDA_00809 3e-176 yeaC S COG0714 MoxR-like ATPases
AFHCFNDA_00810 2.2e-140 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFHCFNDA_00811 3.9e-238 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
AFHCFNDA_00812 9.5e-302 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
AFHCFNDA_00813 3.2e-34 ydjO S Cold-inducible protein YdjO
AFHCFNDA_00815 1.8e-131 ydjN U Involved in the tonB-independent uptake of proteins
AFHCFNDA_00816 4.2e-62 ydjM M Lytic transglycolase
AFHCFNDA_00817 6.4e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
AFHCFNDA_00818 9.5e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
AFHCFNDA_00819 2.6e-139 rsiV S Protein of unknown function (DUF3298)
AFHCFNDA_00820 0.0 yrhL I Acyltransferase family
AFHCFNDA_00821 2e-143 ydjI S virion core protein (lumpy skin disease virus)
AFHCFNDA_00822 1.1e-114 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
AFHCFNDA_00823 1.7e-174 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AFHCFNDA_00824 3.1e-111 pspA KT Phage shock protein A
AFHCFNDA_00825 2.1e-30 yjdJ S Domain of unknown function (DUF4306)
AFHCFNDA_00826 3e-165 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
AFHCFNDA_00827 4.7e-244 gutA G MFS/sugar transport protein
AFHCFNDA_00828 3.3e-197 gutB 1.1.1.14 E Dehydrogenase
AFHCFNDA_00829 0.0 K NB-ARC domain
AFHCFNDA_00830 5.7e-62
AFHCFNDA_00832 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
AFHCFNDA_00835 1.4e-120 xlyB 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AFHCFNDA_00836 4.8e-28 xhlB S SPP1 phage holin
AFHCFNDA_00837 2.4e-30 xhlA S Haemolysin XhlA
AFHCFNDA_00842 2.2e-197 sidC L Phage minor structural protein
AFHCFNDA_00843 3.5e-47
AFHCFNDA_00844 4.3e-46 S Phage-related minor tail protein
AFHCFNDA_00845 6.9e-136
AFHCFNDA_00846 1.9e-25 S Phage tail assembly chaperone protein, TAC
AFHCFNDA_00847 1.3e-34 S Phage tail tube protein
AFHCFNDA_00848 3.8e-29 S Protein of unknown function (DUF3168)
AFHCFNDA_00849 6.2e-38 S Bacteriophage HK97-gp10, putative tail-component
AFHCFNDA_00850 9.5e-29 S Phage head-tail joining protein
AFHCFNDA_00851 3.5e-27 S Phage gp6-like head-tail connector protein
AFHCFNDA_00854 2.9e-54 gpG
AFHCFNDA_00855 5.4e-44 S Phage minor structural protein GP20
AFHCFNDA_00857 1.5e-92 S Phage Mu protein F like protein
AFHCFNDA_00858 1.1e-126 S Phage portal protein, SPP1 Gp6-like
AFHCFNDA_00859 6.4e-179 S Pfam:Terminase_3C
AFHCFNDA_00860 1.5e-71 yqaS L DNA packaging
AFHCFNDA_00864 1.7e-66 S DinB family
AFHCFNDA_00865 8.5e-182 adhP 1.1.1.1 C alcohol dehydrogenase
AFHCFNDA_00866 4e-11
AFHCFNDA_00868 2.9e-26 S Protein of unknown function (DUF4025)
AFHCFNDA_00869 1.1e-10 ywlA S Uncharacterised protein family (UPF0715)
AFHCFNDA_00870 1.1e-128 yoaP 3.1.3.18 K YoaP-like
AFHCFNDA_00871 1.1e-90 J Acetyltransferase (GNAT) domain
AFHCFNDA_00873 1.4e-34
AFHCFNDA_00875 6.6e-100 ynaE S Domain of unknown function (DUF3885)
AFHCFNDA_00876 1.4e-187 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFHCFNDA_00877 1.1e-115 AA10,CBM73 S Pfam:Chitin_bind_3
AFHCFNDA_00879 1.9e-87 yvgO
AFHCFNDA_00881 0.0 yobO M Pectate lyase superfamily protein
AFHCFNDA_00882 1.3e-32 S TM2 domain
AFHCFNDA_00883 1.4e-56 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
AFHCFNDA_00885 1.5e-125 yndL S Replication protein
AFHCFNDA_00887 2e-136 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
AFHCFNDA_00888 5.8e-66 yndM S Protein of unknown function (DUF2512)
AFHCFNDA_00889 1.3e-11 yoaW
AFHCFNDA_00890 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AFHCFNDA_00891 1.2e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
AFHCFNDA_00892 1.6e-109 yneB L resolvase
AFHCFNDA_00893 9.8e-33 ynzC S UPF0291 protein
AFHCFNDA_00894 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AFHCFNDA_00895 7.7e-79 yneE S Sporulation inhibitor of replication protein sirA
AFHCFNDA_00896 2.3e-28 yneF S UPF0154 protein
AFHCFNDA_00897 8.9e-23 ynzD S Spo0E like sporulation regulatory protein
AFHCFNDA_00898 1.2e-121 ccdA O cytochrome c biogenesis protein
AFHCFNDA_00899 1.2e-56 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
AFHCFNDA_00900 5.6e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
AFHCFNDA_00901 2.8e-70 yneK S Protein of unknown function (DUF2621)
AFHCFNDA_00902 5.7e-59 hspX O Spore coat protein
AFHCFNDA_00903 2.3e-19 sspP S Belongs to the SspP family
AFHCFNDA_00904 7.5e-15 sspO S Belongs to the SspO family
AFHCFNDA_00905 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AFHCFNDA_00906 3.6e-88 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AFHCFNDA_00908 1.1e-31 tlp S Belongs to the Tlp family
AFHCFNDA_00909 7.7e-73 yneP S Thioesterase-like superfamily
AFHCFNDA_00910 1.9e-49 yneQ
AFHCFNDA_00911 3.4e-43 yneR S Belongs to the HesB IscA family
AFHCFNDA_00912 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
AFHCFNDA_00913 3.3e-68 yccU S CoA-binding protein
AFHCFNDA_00914 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFHCFNDA_00915 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
AFHCFNDA_00916 4.6e-13
AFHCFNDA_00917 1.2e-39 ynfC
AFHCFNDA_00918 4e-246 agcS E Sodium alanine symporter
AFHCFNDA_00919 5.2e-22 yndG S DoxX-like family
AFHCFNDA_00920 2e-77 yndH S Domain of unknown function (DUF4166)
AFHCFNDA_00921 4.6e-275 yndJ S YndJ-like protein
AFHCFNDA_00922 1.2e-49 S Domain of unknown function (DUF4870)
AFHCFNDA_00923 3.2e-216 T PhoQ Sensor
AFHCFNDA_00924 9e-122 T Transcriptional regulatory protein, C terminal
AFHCFNDA_00925 6.5e-240 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
AFHCFNDA_00926 1.5e-278 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
AFHCFNDA_00927 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_00928 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_00929 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_00930 4.5e-206 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
AFHCFNDA_00931 2e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
AFHCFNDA_00932 5.4e-105 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
AFHCFNDA_00933 2.3e-114 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AFHCFNDA_00934 2.5e-164 bioI 1.14.14.46 C Cytochrome P450
AFHCFNDA_00935 8.5e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AFHCFNDA_00936 4e-122 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AFHCFNDA_00937 3.9e-199 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
AFHCFNDA_00938 1.6e-252 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
AFHCFNDA_00939 8.5e-134 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
AFHCFNDA_00940 1.6e-67 yngA S membrane
AFHCFNDA_00941 8.6e-154 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AFHCFNDA_00942 1.6e-103 yngC S SNARE associated Golgi protein
AFHCFNDA_00943 1.1e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
AFHCFNDA_00944 4.3e-133 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
AFHCFNDA_00945 2.4e-164 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
AFHCFNDA_00946 1.2e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
AFHCFNDA_00947 2.6e-239 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
AFHCFNDA_00948 2.3e-311 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
AFHCFNDA_00949 1.5e-206 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
AFHCFNDA_00950 1.6e-293 yngK T Glycosyl hydrolase-like 10
AFHCFNDA_00951 1.9e-62 yngL S Protein of unknown function (DUF1360)
AFHCFNDA_00952 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
AFHCFNDA_00953 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_00954 6.5e-292 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_00955 6.8e-257 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
AFHCFNDA_00956 3.4e-180 yoxA 5.1.3.3 G Aldose 1-epimerase
AFHCFNDA_00957 9.9e-242 yoeA V MATE efflux family protein
AFHCFNDA_00958 6.1e-94 yoeB S IseA DL-endopeptidase inhibitor
AFHCFNDA_00960 1.9e-95 L Integrase
AFHCFNDA_00961 1.1e-33 yoeD G Helix-turn-helix domain
AFHCFNDA_00962 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
AFHCFNDA_00963 1.1e-188 ybcL EGP Major facilitator Superfamily
AFHCFNDA_00964 6.7e-50 ybzH K Helix-turn-helix domain
AFHCFNDA_00965 1.1e-270 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFHCFNDA_00966 3.6e-290 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
AFHCFNDA_00967 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
AFHCFNDA_00968 3.6e-147 gltC K Transcriptional regulator
AFHCFNDA_00969 5.1e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AFHCFNDA_00970 6.1e-135 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFHCFNDA_00971 3.6e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
AFHCFNDA_00972 1.2e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
AFHCFNDA_00973 1.3e-37 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
AFHCFNDA_00974 1.7e-115 yoxB
AFHCFNDA_00975 4.1e-72 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_00976 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
AFHCFNDA_00977 3.4e-197 gerM S COG5401 Spore germination protein
AFHCFNDA_00978 5.8e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AFHCFNDA_00979 8e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AFHCFNDA_00980 6.1e-88 ysnB S Phosphoesterase
AFHCFNDA_00985 0.0 ilvB 2.2.1.6 E Acetolactate synthase
AFHCFNDA_00986 3.5e-83 ilvN 2.2.1.6 E Acetolactate synthase
AFHCFNDA_00987 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AFHCFNDA_00988 9e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AFHCFNDA_00989 6.5e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
AFHCFNDA_00990 2.5e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFHCFNDA_00991 1.3e-113 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFHCFNDA_00992 1e-187 ysoA H Tetratricopeptide repeat
AFHCFNDA_00993 7.5e-212 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
AFHCFNDA_00994 1.9e-228 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AFHCFNDA_00995 1e-309 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
AFHCFNDA_00996 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AFHCFNDA_00997 1.5e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
AFHCFNDA_00998 5.1e-84 ysxD
AFHCFNDA_00999 2.1e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AFHCFNDA_01000 3.6e-146 hemX O cytochrome C
AFHCFNDA_01001 1.8e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
AFHCFNDA_01002 1.1e-136 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
AFHCFNDA_01003 2.1e-182 hemB 4.2.1.24 H Belongs to the ALAD family
AFHCFNDA_01004 7.1e-242 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
AFHCFNDA_01005 5.7e-150 spoVID M stage VI sporulation protein D
AFHCFNDA_01006 4.9e-185 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AFHCFNDA_01007 3.1e-24
AFHCFNDA_01008 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
AFHCFNDA_01009 2.6e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
AFHCFNDA_01010 4.6e-124 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
AFHCFNDA_01011 2.1e-124 spoIIB S Sporulation related domain
AFHCFNDA_01012 3.8e-99 maf D septum formation protein Maf
AFHCFNDA_01013 4.5e-126 radC E Belongs to the UPF0758 family
AFHCFNDA_01014 1.3e-182 mreB D Rod shape-determining protein MreB
AFHCFNDA_01015 6.8e-156 mreC M Involved in formation and maintenance of cell shape
AFHCFNDA_01016 1.1e-81 mreD M shape-determining protein
AFHCFNDA_01017 2.2e-101 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
AFHCFNDA_01018 2.3e-142 minD D Belongs to the ParA family
AFHCFNDA_01019 3.8e-137 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
AFHCFNDA_01020 2.3e-156 spoIVFB S Stage IV sporulation protein
AFHCFNDA_01021 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
AFHCFNDA_01022 7e-56 ysxB J ribosomal protein
AFHCFNDA_01023 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
AFHCFNDA_01024 4.8e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
AFHCFNDA_01025 6.4e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFHCFNDA_01026 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
AFHCFNDA_01027 6.1e-157 pheA 4.2.1.51 E Prephenate dehydratase
AFHCFNDA_01028 2.9e-88 niaR S small molecule binding protein (contains 3H domain)
AFHCFNDA_01029 3.4e-211 nifS 2.8.1.7 E Cysteine desulfurase
AFHCFNDA_01030 1.3e-277 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
AFHCFNDA_01031 1e-140 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
AFHCFNDA_01032 5.4e-206 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AFHCFNDA_01033 2.1e-112 safA M spore coat assembly protein SafA
AFHCFNDA_01034 6.1e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFHCFNDA_01036 5.9e-91 bofC S BofC C-terminal domain
AFHCFNDA_01037 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
AFHCFNDA_01038 2.9e-182 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
AFHCFNDA_01039 2.8e-20 yrzS S Protein of unknown function (DUF2905)
AFHCFNDA_01040 2.7e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AFHCFNDA_01041 7.5e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
AFHCFNDA_01042 2.5e-37 yajC U Preprotein translocase subunit YajC
AFHCFNDA_01043 5.3e-60 yrzE S Protein of unknown function (DUF3792)
AFHCFNDA_01044 5.1e-103 yrbG S membrane
AFHCFNDA_01045 9.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFHCFNDA_01046 8e-48 yrzD S Post-transcriptional regulator
AFHCFNDA_01047 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AFHCFNDA_01048 4.6e-80 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
AFHCFNDA_01049 2.7e-44 yrvD S Lipopolysaccharide assembly protein A domain
AFHCFNDA_01050 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
AFHCFNDA_01051 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AFHCFNDA_01052 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AFHCFNDA_01053 2e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
AFHCFNDA_01054 1e-266 lytH 3.5.1.28 M COG3103 SH3 domain protein
AFHCFNDA_01057 4.5e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
AFHCFNDA_01058 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AFHCFNDA_01059 3.3e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
AFHCFNDA_01060 7e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
AFHCFNDA_01061 2.9e-63 cymR K Transcriptional regulator
AFHCFNDA_01062 7e-209 iscS 2.8.1.7 E Cysteine desulfurase
AFHCFNDA_01063 5e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
AFHCFNDA_01064 1.7e-18 S COG0457 FOG TPR repeat
AFHCFNDA_01065 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
AFHCFNDA_01066 2.3e-78 yrrD S protein conserved in bacteria
AFHCFNDA_01067 2.9e-30 yrzR
AFHCFNDA_01068 2.1e-08 S Protein of unknown function (DUF3918)
AFHCFNDA_01069 6e-104 glnP P ABC transporter
AFHCFNDA_01070 8e-109 gluC P ABC transporter
AFHCFNDA_01071 4.4e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
AFHCFNDA_01072 2.5e-127 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
AFHCFNDA_01073 2.1e-159 yrrI S AI-2E family transporter
AFHCFNDA_01074 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AFHCFNDA_01075 1.7e-41 yrzL S Belongs to the UPF0297 family
AFHCFNDA_01076 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AFHCFNDA_01077 7.1e-46 yrzB S Belongs to the UPF0473 family
AFHCFNDA_01078 6.9e-190 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFHCFNDA_01079 4e-116 yrrM 2.1.1.104 S O-methyltransferase
AFHCFNDA_01080 2.9e-173 yegQ O Peptidase U32
AFHCFNDA_01081 1.6e-246 yegQ O COG0826 Collagenase and related proteases
AFHCFNDA_01082 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
AFHCFNDA_01083 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
AFHCFNDA_01084 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
AFHCFNDA_01085 2.6e-68 yrrS S Protein of unknown function (DUF1510)
AFHCFNDA_01086 4.1e-27 yrzA S Protein of unknown function (DUF2536)
AFHCFNDA_01087 7.1e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
AFHCFNDA_01088 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AFHCFNDA_01089 8e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
AFHCFNDA_01090 1.4e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFHCFNDA_01091 1.3e-34 yrhC S YrhC-like protein
AFHCFNDA_01092 7e-81 yrhD S Protein of unknown function (DUF1641)
AFHCFNDA_01093 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
AFHCFNDA_01094 1.9e-59 yrhF S Uncharacterized conserved protein (DUF2294)
AFHCFNDA_01095 8.8e-142 focA P Formate nitrite
AFHCFNDA_01097 1.5e-92 yrhH Q methyltransferase
AFHCFNDA_01098 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
AFHCFNDA_01099 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
AFHCFNDA_01100 3.8e-213 ynfM EGP Major facilitator Superfamily
AFHCFNDA_01101 4.1e-164 yybE K Transcriptional regulator
AFHCFNDA_01102 8.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AFHCFNDA_01103 1.3e-179 romA S Beta-lactamase superfamily domain
AFHCFNDA_01104 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
AFHCFNDA_01105 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
AFHCFNDA_01106 5.8e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFHCFNDA_01107 7.8e-129 glvR K Helix-turn-helix domain, rpiR family
AFHCFNDA_01108 1.2e-51 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
AFHCFNDA_01109 1.7e-72 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
AFHCFNDA_01110 8.5e-145 S hydrolase
AFHCFNDA_01112 4.4e-91 yrdA S DinB family
AFHCFNDA_01113 3.3e-81 yyaR K Acetyltransferase (GNAT) domain
AFHCFNDA_01114 2.8e-220 tetL EGP Major facilitator Superfamily
AFHCFNDA_01115 4.4e-97 adk 2.7.4.3 F adenylate kinase activity
AFHCFNDA_01117 1e-36 ydeE K AraC family transcriptional regulator
AFHCFNDA_01118 2.3e-60 K Transcriptional regulator PadR-like family
AFHCFNDA_01119 5.4e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
AFHCFNDA_01120 5.2e-207 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AFHCFNDA_01121 1.7e-36 G Cupin
AFHCFNDA_01122 1.1e-42 yjcN
AFHCFNDA_01125 2.4e-132 S Aspartate phosphatase response regulator
AFHCFNDA_01126 4e-14
AFHCFNDA_01128 2.8e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
AFHCFNDA_01129 5.5e-193 yubA S transporter activity
AFHCFNDA_01130 9.1e-181 ygjR S Oxidoreductase
AFHCFNDA_01131 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
AFHCFNDA_01132 6.9e-228 mcpA NT chemotaxis protein
AFHCFNDA_01133 2.2e-218 mcpA NT chemotaxis protein
AFHCFNDA_01134 1.3e-213 mcpA NT chemotaxis protein
AFHCFNDA_01135 5.5e-209 mcpA NT chemotaxis protein
AFHCFNDA_01136 3.3e-135 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
AFHCFNDA_01137 5.8e-39
AFHCFNDA_01138 3.6e-186 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
AFHCFNDA_01139 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
AFHCFNDA_01140 8.1e-230 yugS S COG1253 Hemolysins and related proteins containing CBS domains
AFHCFNDA_01141 4.1e-116 yugP S Zn-dependent protease
AFHCFNDA_01142 6.5e-17
AFHCFNDA_01143 1e-27 mstX S Membrane-integrating protein Mistic
AFHCFNDA_01144 1.6e-177 yugO P COG1226 Kef-type K transport systems
AFHCFNDA_01145 5e-69 yugN S YugN-like family
AFHCFNDA_01147 1.9e-258 pgi 5.3.1.9 G Belongs to the GPI family
AFHCFNDA_01148 5.8e-227 yugK C Dehydrogenase
AFHCFNDA_01149 1e-223 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
AFHCFNDA_01150 6.8e-34 yuzA S Domain of unknown function (DUF378)
AFHCFNDA_01151 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
AFHCFNDA_01152 3e-207 yugH 2.6.1.1 E Aminotransferase
AFHCFNDA_01153 5.8e-83 alaR K Transcriptional regulator
AFHCFNDA_01154 2e-149 yugF I Hydrolase
AFHCFNDA_01155 5e-38 yugE S Domain of unknown function (DUF1871)
AFHCFNDA_01156 9.9e-219 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
AFHCFNDA_01157 1.7e-138 T PhoQ Sensor
AFHCFNDA_01158 1.2e-65 T PhoQ Sensor
AFHCFNDA_01159 7.4e-62 kapB G Kinase associated protein B
AFHCFNDA_01160 4.7e-115 kapD L the KinA pathway to sporulation
AFHCFNDA_01161 1.5e-165 yuxJ EGP Major facilitator Superfamily
AFHCFNDA_01162 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
AFHCFNDA_01163 1e-69 yuxK S protein conserved in bacteria
AFHCFNDA_01164 1.1e-71 yufK S Family of unknown function (DUF5366)
AFHCFNDA_01165 4.2e-292 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
AFHCFNDA_01166 8.7e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
AFHCFNDA_01167 5.1e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
AFHCFNDA_01168 1.7e-279 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
AFHCFNDA_01169 7.4e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
AFHCFNDA_01170 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
AFHCFNDA_01171 9.8e-11
AFHCFNDA_01172 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
AFHCFNDA_01173 6.6e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFHCFNDA_01174 2.2e-49 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFHCFNDA_01175 7.4e-259 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFHCFNDA_01176 5.5e-75 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFHCFNDA_01177 1.4e-36 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
AFHCFNDA_01178 9.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
AFHCFNDA_01179 2.6e-59 ydiI Q protein, possibly involved in aromatic compounds catabolism
AFHCFNDA_01180 6.9e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFHCFNDA_01181 4.2e-253 comP 2.7.13.3 T Histidine kinase
AFHCFNDA_01183 2.9e-61 comQ H Belongs to the FPP GGPP synthase family
AFHCFNDA_01185 1.6e-47 yuzC
AFHCFNDA_01186 8.2e-224 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
AFHCFNDA_01187 1.7e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AFHCFNDA_01188 3e-101 pncA Q COG1335 Amidases related to nicotinamidase
AFHCFNDA_01189 1.1e-65 yueI S Protein of unknown function (DUF1694)
AFHCFNDA_01190 4.8e-38 yueH S YueH-like protein
AFHCFNDA_01191 7.1e-33 yueG S Spore germination protein gerPA/gerPF
AFHCFNDA_01192 4.1e-182 yueF S transporter activity
AFHCFNDA_01193 1.6e-22 S Protein of unknown function (DUF2642)
AFHCFNDA_01194 2.4e-95 yueE S phosphohydrolase
AFHCFNDA_01195 3.4e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_01196 2.7e-74 yueC S Family of unknown function (DUF5383)
AFHCFNDA_01197 0.0 esaA S type VII secretion protein EsaA
AFHCFNDA_01198 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
AFHCFNDA_01199 6.3e-198 essB S WXG100 protein secretion system (Wss), protein YukC
AFHCFNDA_01200 9.6e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
AFHCFNDA_01201 1.7e-45 esxA S Belongs to the WXG100 family
AFHCFNDA_01202 6.8e-226 yukF QT Transcriptional regulator
AFHCFNDA_01203 1.3e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
AFHCFNDA_01204 1.9e-129 yukJ S Uncharacterized conserved protein (DUF2278)
AFHCFNDA_01205 1.7e-31 mbtH S MbtH-like protein
AFHCFNDA_01206 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_01207 2.3e-162 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
AFHCFNDA_01208 3.6e-307 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
AFHCFNDA_01209 5.8e-214 entC 5.4.4.2 HQ Isochorismate synthase
AFHCFNDA_01210 2.2e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFHCFNDA_01211 8.9e-156 besA S Putative esterase
AFHCFNDA_01212 3e-118 yuiH S Oxidoreductase molybdopterin binding domain
AFHCFNDA_01213 1.2e-100 bioY S Biotin biosynthesis protein
AFHCFNDA_01214 1.5e-207 yuiF S antiporter
AFHCFNDA_01215 6e-277 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AFHCFNDA_01216 6.5e-76 yuiD S protein conserved in bacteria
AFHCFNDA_01217 1.3e-114 yuiC S protein conserved in bacteria
AFHCFNDA_01218 4.9e-27 yuiB S Putative membrane protein
AFHCFNDA_01219 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
AFHCFNDA_01220 1.8e-184 yumC 1.18.1.2, 1.19.1.1 C reductase
AFHCFNDA_01222 3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
AFHCFNDA_01223 2e-27
AFHCFNDA_01224 1.4e-66 CP Membrane
AFHCFNDA_01225 3.5e-118 V ABC transporter
AFHCFNDA_01227 5.4e-32 S Bacteriocin class IId cyclical uberolysin-like
AFHCFNDA_01229 6.6e-42 rimJ 2.3.1.128 J Alanine acetyltransferase
AFHCFNDA_01230 1.3e-129 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
AFHCFNDA_01231 2.6e-61 erpA S Belongs to the HesB IscA family
AFHCFNDA_01232 3.8e-159 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AFHCFNDA_01233 3.6e-203 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFHCFNDA_01234 1.7e-37 yuzB S Belongs to the UPF0349 family
AFHCFNDA_01235 5.7e-205 yutJ 1.6.99.3 C NADH dehydrogenase
AFHCFNDA_01236 4.1e-53 yuzD S protein conserved in bacteria
AFHCFNDA_01237 1.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
AFHCFNDA_01238 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
AFHCFNDA_01239 3.1e-162 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
AFHCFNDA_01240 4.5e-194 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AFHCFNDA_01241 5.1e-240 hom 1.1.1.3 E homoserine dehydrogenase
AFHCFNDA_01242 6.3e-193 yutH S Spore coat protein
AFHCFNDA_01243 5.2e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
AFHCFNDA_01244 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
AFHCFNDA_01245 8.9e-72 yutE S Protein of unknown function DUF86
AFHCFNDA_01246 1.7e-47 yutD S protein conserved in bacteria
AFHCFNDA_01247 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AFHCFNDA_01248 2.5e-191 lytH M Peptidase, M23
AFHCFNDA_01249 2.2e-213 glcP G Major Facilitator Superfamily
AFHCFNDA_01250 1e-245 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFHCFNDA_01251 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
AFHCFNDA_01252 2.9e-201 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
AFHCFNDA_01253 1.1e-222 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
AFHCFNDA_01254 3.2e-170 ybaS 1.1.1.58 S Na -dependent transporter
AFHCFNDA_01255 2.2e-102 ybbA S Putative esterase
AFHCFNDA_01256 7e-176 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_01257 1.5e-175 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_01258 4.5e-169 feuA P Iron-uptake system-binding protein
AFHCFNDA_01259 1.3e-290 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
AFHCFNDA_01260 7.8e-230 ybbC 3.2.1.52 S protein conserved in bacteria
AFHCFNDA_01261 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
AFHCFNDA_01262 1.5e-236 yfeW 3.4.16.4 V Belongs to the UPF0214 family
AFHCFNDA_01263 1.9e-229 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFHCFNDA_01264 8.3e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AFHCFNDA_01265 4.9e-59 ybbJ J acetyltransferase
AFHCFNDA_01266 1.2e-74 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
AFHCFNDA_01270 1.5e-07
AFHCFNDA_01272 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
AFHCFNDA_01273 5.2e-113 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
AFHCFNDA_01274 1.1e-144 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFHCFNDA_01275 1.9e-216 ybbR S protein conserved in bacteria
AFHCFNDA_01276 2.3e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFHCFNDA_01277 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
AFHCFNDA_01278 9.2e-36
AFHCFNDA_01279 1.2e-198 O growth
AFHCFNDA_01280 1.1e-52 S ABC-2 family transporter protein
AFHCFNDA_01281 1.3e-98 ybdN
AFHCFNDA_01282 2.7e-131 ybdO S Domain of unknown function (DUF4885)
AFHCFNDA_01283 4.4e-160 dkgB S Aldo/keto reductase family
AFHCFNDA_01284 1.5e-92 yxaC M effector of murein hydrolase
AFHCFNDA_01285 2.2e-50 S LrgA family
AFHCFNDA_01286 2.3e-67 yxaD K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_01287 2.7e-255 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
AFHCFNDA_01288 3.6e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
AFHCFNDA_01289 8.9e-118 T COG4585 Signal transduction histidine kinase
AFHCFNDA_01290 2.2e-48 T COG4585 Signal transduction histidine kinase
AFHCFNDA_01291 3e-100 KT LuxR family transcriptional regulator
AFHCFNDA_01292 6.4e-160 V COG1131 ABC-type multidrug transport system, ATPase component
AFHCFNDA_01293 8.4e-189 V COG0842 ABC-type multidrug transport system, permease component
AFHCFNDA_01294 1.8e-180 V ABC-2 family transporter protein
AFHCFNDA_01295 9.2e-23
AFHCFNDA_01296 1.5e-75 S Domain of unknown function (DUF4879)
AFHCFNDA_01297 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
AFHCFNDA_01298 2.5e-100 yqeB
AFHCFNDA_01299 2.3e-38 ybyB
AFHCFNDA_01300 1.2e-275 ybeC E amino acid
AFHCFNDA_01301 1.2e-15 S Protein of unknown function (DUF2651)
AFHCFNDA_01302 2e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AFHCFNDA_01303 2.5e-71 glpT G -transporter
AFHCFNDA_01304 5.9e-160 glpT G -transporter
AFHCFNDA_01305 9.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
AFHCFNDA_01307 3.9e-81 K Helix-turn-helix XRE-family like proteins
AFHCFNDA_01308 7e-187 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
AFHCFNDA_01309 1.7e-207 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AFHCFNDA_01310 1.9e-92 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFHCFNDA_01311 5.1e-84 ybfM S SNARE associated Golgi protein
AFHCFNDA_01312 9e-150 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
AFHCFNDA_01313 2.8e-39 ybfN
AFHCFNDA_01314 2.6e-188 yceA S Belongs to the UPF0176 family
AFHCFNDA_01315 6.3e-211 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFHCFNDA_01316 1.9e-192 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AFHCFNDA_01317 9.3e-237 mmuP E amino acid
AFHCFNDA_01318 7.7e-177 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
AFHCFNDA_01319 2.4e-251 agcS E Sodium alanine symporter
AFHCFNDA_01320 8.3e-72 glsA 3.5.1.2 E Belongs to the glutaminase family
AFHCFNDA_01321 2.6e-34 glsA 3.5.1.2 E Belongs to the glutaminase family
AFHCFNDA_01322 4.6e-201 phoQ 2.7.13.3 T Histidine kinase
AFHCFNDA_01323 1.7e-155 glnL T Regulator
AFHCFNDA_01324 3.5e-126 ycbJ S Macrolide 2'-phosphotransferase
AFHCFNDA_01325 4.5e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
AFHCFNDA_01326 2.1e-152 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFHCFNDA_01327 3.5e-91 ydfN C nitroreductase
AFHCFNDA_01328 8.6e-181 ydfO E COG0346 Lactoylglutathione lyase and related lyases
AFHCFNDA_01329 7.5e-62 mhqP S DoxX
AFHCFNDA_01330 3.5e-55 traF CO Thioredoxin
AFHCFNDA_01331 1.7e-11 L COG3666 Transposase and inactivated derivatives
AFHCFNDA_01332 7.4e-62 ycbP S Protein of unknown function (DUF2512)
AFHCFNDA_01333 4.8e-78 sleB 3.5.1.28 M Cell wall
AFHCFNDA_01334 2.6e-261 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
AFHCFNDA_01335 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
AFHCFNDA_01336 7.6e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFHCFNDA_01337 5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AFHCFNDA_01338 2.7e-189 ycbU E Selenocysteine lyase
AFHCFNDA_01339 1.4e-235 lmrB EGP the major facilitator superfamily
AFHCFNDA_01340 3.6e-97 yxaF K Transcriptional regulator
AFHCFNDA_01341 7.5e-46 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
AFHCFNDA_01342 6.4e-16 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
AFHCFNDA_01343 8e-191 yccF K DNA-templated transcriptional preinitiation complex assembly
AFHCFNDA_01344 7.3e-21 yccK C Aldo keto reductase
AFHCFNDA_01345 8.7e-134 yccK C Aldo keto reductase
AFHCFNDA_01346 2.7e-164 ycdA S Domain of unknown function (DUF5105)
AFHCFNDA_01347 1.5e-24 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
AFHCFNDA_01348 3.4e-195 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
AFHCFNDA_01349 3e-251 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
AFHCFNDA_01350 1.6e-88 cwlK M D-alanyl-D-alanine carboxypeptidase
AFHCFNDA_01351 2e-171 S response regulator aspartate phosphatase
AFHCFNDA_01352 2e-135 IQ Enoyl-(Acyl carrier protein) reductase
AFHCFNDA_01353 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
AFHCFNDA_01354 1.6e-48 S Domain of unknown function (DUF4188)
AFHCFNDA_01355 1.5e-47 padR K Virulence activator alpha C-term
AFHCFNDA_01356 1.1e-162 adcA P Belongs to the bacterial solute-binding protein 9 family
AFHCFNDA_01357 1.6e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
AFHCFNDA_01358 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
AFHCFNDA_01359 1.4e-181 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFHCFNDA_01360 6.2e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
AFHCFNDA_01361 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
AFHCFNDA_01362 3.3e-106 yceE T proteins involved in stress response, homologs of TerZ and
AFHCFNDA_01363 1.7e-137 terC P Protein of unknown function (DUF475)
AFHCFNDA_01364 2.7e-307 yceG S Putative component of 'biosynthetic module'
AFHCFNDA_01365 4.3e-192 yceH P Belongs to the TelA family
AFHCFNDA_01366 1.8e-207 naiP P Uncharacterised MFS-type transporter YbfB
AFHCFNDA_01368 1.4e-226 proV 3.6.3.32 E glycine betaine
AFHCFNDA_01369 6.9e-137 opuAB P glycine betaine
AFHCFNDA_01370 4.2e-161 opuAC E glycine betaine
AFHCFNDA_01371 1e-204 amhX S amidohydrolase
AFHCFNDA_01372 7.4e-188 ycgA S Membrane
AFHCFNDA_01373 1.3e-24 ycgA S Membrane
AFHCFNDA_01374 5.2e-42 ycgB
AFHCFNDA_01375 2.3e-12 S RDD family
AFHCFNDA_01376 2.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
AFHCFNDA_01377 3.2e-257 mdr EGP Major facilitator Superfamily
AFHCFNDA_01378 2.9e-73 emrR K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_01380 8.5e-162 ygxA S Nucleotidyltransferase-like
AFHCFNDA_01381 2.1e-55 ygzB S UPF0295 protein
AFHCFNDA_01382 3.1e-80 perR P Belongs to the Fur family
AFHCFNDA_01383 5e-84 bcp 1.11.1.15 O Peroxiredoxin
AFHCFNDA_01384 1.1e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
AFHCFNDA_01385 5e-177 ygaE S Membrane
AFHCFNDA_01386 3.1e-301 ygaD V ABC transporter
AFHCFNDA_01387 2.2e-104 ygaC J Belongs to the UPF0374 family
AFHCFNDA_01388 1.5e-37 ygaB S YgaB-like protein
AFHCFNDA_01390 2e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_01391 1.8e-36 yfhS
AFHCFNDA_01392 1.4e-203 mutY L A G-specific
AFHCFNDA_01393 5.9e-180 yfhP S membrane-bound metal-dependent
AFHCFNDA_01394 0.0 yfhO S Bacterial membrane protein YfhO
AFHCFNDA_01395 1.1e-183 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFHCFNDA_01396 6.1e-123 yfhM S Alpha/beta hydrolase family
AFHCFNDA_01397 2e-31 yfhL S SdpI/YhfL protein family
AFHCFNDA_01398 1.2e-86 batE T Bacterial SH3 domain homologues
AFHCFNDA_01399 8.3e-44 yfhJ S WVELL protein
AFHCFNDA_01400 1.7e-157 mpr 3.4.21.19 M Belongs to the peptidase S1B family
AFHCFNDA_01402 5e-177 yfhI EGP Major facilitator Superfamily
AFHCFNDA_01403 4.7e-46 yfhH S Protein of unknown function (DUF1811)
AFHCFNDA_01404 3.1e-139 recX 2.4.1.337 GT4 S Modulates RecA activity
AFHCFNDA_01405 2.1e-163 yfhF S nucleoside-diphosphate sugar epimerase
AFHCFNDA_01407 1e-24 yfhD S YfhD-like protein
AFHCFNDA_01408 5.9e-103 yfhC C nitroreductase
AFHCFNDA_01409 5.5e-153 yfhB 5.3.3.17 S PhzF family
AFHCFNDA_01410 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AFHCFNDA_01411 2.4e-78 yfiV K transcriptional
AFHCFNDA_01412 9.2e-284 yfiU EGP Major facilitator Superfamily
AFHCFNDA_01413 6.1e-94 yfiT S Belongs to the metal hydrolase YfiT family
AFHCFNDA_01414 2.2e-44 yrdF K ribonuclease inhibitor
AFHCFNDA_01415 8.5e-172 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
AFHCFNDA_01416 9.7e-101 1.6.5.2 S NADPH-dependent FMN reductase
AFHCFNDA_01417 2e-92 padR K transcriptional
AFHCFNDA_01418 1.7e-70 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
AFHCFNDA_01419 3.7e-77 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
AFHCFNDA_01420 1.5e-155 yfiE 1.13.11.2 S glyoxalase
AFHCFNDA_01421 9.2e-63 mhqP S DoxX
AFHCFNDA_01422 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
AFHCFNDA_01423 1.9e-303 yfiB3 V ABC transporter
AFHCFNDA_01424 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
AFHCFNDA_01425 2.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFHCFNDA_01426 4.3e-138 glvR F Helix-turn-helix domain, rpiR family
AFHCFNDA_01427 1e-259 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
AFHCFNDA_01428 3.2e-15 sspH S Belongs to the SspH family
AFHCFNDA_01429 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
AFHCFNDA_01430 3.9e-238 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFHCFNDA_01431 6.8e-207 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFHCFNDA_01432 2e-186 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFHCFNDA_01433 2.5e-186 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFHCFNDA_01434 6e-79 yfjM S Psort location Cytoplasmic, score
AFHCFNDA_01435 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFHCFNDA_01436 4.7e-45 S YfzA-like protein
AFHCFNDA_01443 0.0 KLT Protein kinase domain
AFHCFNDA_01444 1.3e-246 lmrA 3.6.3.44 V ABC transporter
AFHCFNDA_01445 1.3e-79 O Subtilase family
AFHCFNDA_01446 3.4e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFHCFNDA_01447 2.8e-157 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AFHCFNDA_01448 2.5e-183 corA P Mediates influx of magnesium ions
AFHCFNDA_01449 1.8e-28
AFHCFNDA_01450 1.2e-68 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
AFHCFNDA_01451 6.2e-45 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
AFHCFNDA_01452 4.9e-153 pdaA G deacetylase
AFHCFNDA_01453 4.9e-27 yfjT
AFHCFNDA_01454 2.1e-218 yfkA S YfkB-like domain
AFHCFNDA_01455 1.1e-47 yfkC M Mechanosensitive ion channel
AFHCFNDA_01456 1.1e-139 yfkD S YfkD-like protein
AFHCFNDA_01457 1.5e-181 cax P COG0387 Ca2 H antiporter
AFHCFNDA_01458 1.1e-214 ycaD EGP COG0477 Permeases of the major facilitator superfamily
AFHCFNDA_01459 7.1e-142 yihY S Belongs to the UPF0761 family
AFHCFNDA_01460 4.4e-47 yfkI S gas vesicle protein
AFHCFNDA_01461 2.2e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFHCFNDA_01462 3.9e-28 yfkK S Belongs to the UPF0435 family
AFHCFNDA_01463 8.4e-189 ydiM EGP Major facilitator Superfamily
AFHCFNDA_01464 4e-128 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
AFHCFNDA_01465 3.2e-161 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFHCFNDA_01466 2.6e-178 K helix_turn _helix lactose operon repressor
AFHCFNDA_01467 4.2e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
AFHCFNDA_01468 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
AFHCFNDA_01469 6.8e-185 yibE S YibE/F-like protein
AFHCFNDA_01470 3.8e-118 yibF S YibE/F-like protein
AFHCFNDA_01471 4.6e-120 yfkO C nitroreductase
AFHCFNDA_01472 6.1e-126 treR K transcriptional
AFHCFNDA_01473 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
AFHCFNDA_01474 3.1e-238 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFHCFNDA_01475 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
AFHCFNDA_01476 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
AFHCFNDA_01477 4.5e-76 cotP O Belongs to the small heat shock protein (HSP20) family
AFHCFNDA_01478 4.7e-61 yhdN S Domain of unknown function (DUF1992)
AFHCFNDA_01479 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AFHCFNDA_01480 8.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
AFHCFNDA_01481 2.4e-240 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
AFHCFNDA_01482 6.8e-136 map 3.4.11.18 E Methionine aminopeptidase
AFHCFNDA_01483 1.1e-15 yflH S Protein of unknown function (DUF3243)
AFHCFNDA_01484 1.6e-18 yflI
AFHCFNDA_01485 1.5e-14 yflJ S Protein of unknown function (DUF2639)
AFHCFNDA_01486 2.3e-119 yflK S protein conserved in bacteria
AFHCFNDA_01487 1.3e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
AFHCFNDA_01488 1.9e-211 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AFHCFNDA_01489 4.6e-143 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
AFHCFNDA_01490 7.4e-223 citM C Citrate transporter
AFHCFNDA_01491 1.7e-171 yflP S Tripartite tricarboxylate transporter family receptor
AFHCFNDA_01492 6e-115 citT T response regulator
AFHCFNDA_01493 6.9e-252 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
AFHCFNDA_01494 4.6e-80 srtA 3.4.22.70 M Sortase family
AFHCFNDA_01495 9.6e-106 M cell wall anchor domain
AFHCFNDA_01496 4.6e-36 S YolD-like protein
AFHCFNDA_01497 1.3e-296 K Psort location Cytoplasmic, score
AFHCFNDA_01498 1.1e-197 K Psort location Cytoplasmic, score
AFHCFNDA_01499 3e-276 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_01500 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
AFHCFNDA_01501 2.7e-137 srfAD Q thioesterase
AFHCFNDA_01502 8.8e-248 bamJ E Aminotransferase class I and II
AFHCFNDA_01503 5.5e-121 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
AFHCFNDA_01504 8e-106 yczE S membrane
AFHCFNDA_01505 1.7e-131 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
AFHCFNDA_01506 1e-117 tcyB P COG0765 ABC-type amino acid transport system, permease component
AFHCFNDA_01507 6.7e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
AFHCFNDA_01508 1.6e-152 bsdA K LysR substrate binding domain
AFHCFNDA_01509 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
AFHCFNDA_01510 1.5e-280 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
AFHCFNDA_01511 9.2e-36 bsdD 4.1.1.61 S response to toxic substance
AFHCFNDA_01512 6.6e-73 yclD
AFHCFNDA_01513 6.8e-265 dtpT E amino acid peptide transporter
AFHCFNDA_01514 1.5e-263 yclG M Pectate lyase superfamily protein
AFHCFNDA_01516 1.7e-280 gerKA EG Spore germination protein
AFHCFNDA_01517 5.5e-228 gerKC S spore germination
AFHCFNDA_01518 1.9e-190 gerKB F Spore germination protein
AFHCFNDA_01519 3e-248 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFHCFNDA_01520 2.2e-90 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFHCFNDA_01521 3.4e-138 yxeM M Belongs to the bacterial solute-binding protein 3 family
AFHCFNDA_01522 1.7e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
AFHCFNDA_01523 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
AFHCFNDA_01524 1.6e-213 yxeP 3.5.1.47 E hydrolase activity
AFHCFNDA_01525 1.2e-239 yxeQ S MmgE/PrpD family
AFHCFNDA_01526 1.8e-119 yclH P ABC transporter
AFHCFNDA_01527 1.1e-222 yclI V ABC transporter (permease) YclI
AFHCFNDA_01528 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_01529 9.5e-256 T PhoQ Sensor
AFHCFNDA_01530 4.6e-75 S aspartate phosphatase
AFHCFNDA_01533 2.7e-247 lysC 2.7.2.4 E Belongs to the aspartokinase family
AFHCFNDA_01534 6.3e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_01535 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_01536 5.8e-135 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
AFHCFNDA_01537 7.4e-172 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
AFHCFNDA_01538 8.1e-247 ycnB EGP Major facilitator Superfamily
AFHCFNDA_01539 1.1e-148 ycnC K Transcriptional regulator
AFHCFNDA_01540 1.4e-133 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
AFHCFNDA_01541 1.4e-44 ycnE S Monooxygenase
AFHCFNDA_01542 1.2e-49 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
AFHCFNDA_01543 4.7e-255 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFHCFNDA_01544 1.1e-210 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFHCFNDA_01545 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFHCFNDA_01546 2.6e-147 glcU U Glucose uptake
AFHCFNDA_01547 3.3e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_01548 6.2e-95 ycnI S protein conserved in bacteria
AFHCFNDA_01549 2.4e-287 ycnJ P protein, homolog of Cu resistance protein CopC
AFHCFNDA_01550 8.4e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
AFHCFNDA_01551 4.3e-53
AFHCFNDA_01552 2.1e-231 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
AFHCFNDA_01553 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
AFHCFNDA_01554 1.8e-201 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
AFHCFNDA_01555 2.7e-59 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
AFHCFNDA_01557 2.6e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
AFHCFNDA_01558 1e-131 ycsF S Belongs to the UPF0271 (lamB) family
AFHCFNDA_01559 4.5e-206 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
AFHCFNDA_01560 5.1e-142 ycsI S Belongs to the D-glutamate cyclase family
AFHCFNDA_01561 3.1e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
AFHCFNDA_01562 5.1e-179 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
AFHCFNDA_01563 1.5e-125 kipR K Transcriptional regulator
AFHCFNDA_01564 2e-112 ycsK E anatomical structure formation involved in morphogenesis
AFHCFNDA_01566 5.2e-53 yczJ S biosynthesis
AFHCFNDA_01567 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
AFHCFNDA_01568 1.6e-168 ydhF S Oxidoreductase
AFHCFNDA_01569 0.0 mtlR K transcriptional regulator, MtlR
AFHCFNDA_01570 9.7e-283 ydaB IQ acyl-CoA ligase
AFHCFNDA_01571 8.3e-154 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_01572 9.6e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
AFHCFNDA_01573 3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
AFHCFNDA_01574 3.4e-76 ydaG 1.4.3.5 S general stress protein
AFHCFNDA_01575 1.2e-135 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
AFHCFNDA_01576 3.9e-47 ydzA EGP Major facilitator Superfamily
AFHCFNDA_01577 4.3e-74 lrpC K Transcriptional regulator
AFHCFNDA_01578 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AFHCFNDA_01579 2.9e-188 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
AFHCFNDA_01580 6.5e-143 ydaK T Diguanylate cyclase, GGDEF domain
AFHCFNDA_01581 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
AFHCFNDA_01582 1e-229 ydaM M Glycosyl transferase family group 2
AFHCFNDA_01583 0.0 ydaN S Bacterial cellulose synthase subunit
AFHCFNDA_01584 0.0 ydaO E amino acid
AFHCFNDA_01585 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
AFHCFNDA_01586 7.1e-61 K acetyltransferase
AFHCFNDA_01587 2.8e-87 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AFHCFNDA_01588 4.8e-69
AFHCFNDA_01589 2e-183 S Histidine kinase
AFHCFNDA_01592 4.7e-39
AFHCFNDA_01593 1.9e-223 mntH P H( )-stimulated, divalent metal cation uptake system
AFHCFNDA_01596 5.5e-33 ydaT
AFHCFNDA_01597 5.8e-73 yvaD S Family of unknown function (DUF5360)
AFHCFNDA_01598 1.1e-48 yvaE P Small Multidrug Resistance protein
AFHCFNDA_01599 1.2e-135 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
AFHCFNDA_01601 7e-56 ydbB G Cupin domain
AFHCFNDA_01602 5.1e-57 ydbC S Domain of unknown function (DUF4937
AFHCFNDA_01603 2.5e-152 ydbD P Catalase
AFHCFNDA_01604 1.4e-41 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
AFHCFNDA_01605 3.6e-135 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
AFHCFNDA_01606 1.3e-293 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
AFHCFNDA_01607 1.1e-113 dctR T COG4565 Response regulator of citrate malate metabolism
AFHCFNDA_01608 2.7e-222 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFHCFNDA_01609 2.2e-156 ydbI S AI-2E family transporter
AFHCFNDA_01610 5.7e-169 ydbJ V ABC transporter, ATP-binding protein
AFHCFNDA_01611 3.3e-53 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
AFHCFNDA_01612 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFHCFNDA_01613 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFHCFNDA_01614 8.1e-38 yaaB S Domain of unknown function (DUF370)
AFHCFNDA_01615 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AFHCFNDA_01616 2.4e-33 yaaA S S4 domain
AFHCFNDA_01617 8e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
AFHCFNDA_01618 4.3e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AFHCFNDA_01619 1.2e-50 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
AFHCFNDA_01620 4.3e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFHCFNDA_01621 8.2e-106 jag S single-stranded nucleic acid binding R3H
AFHCFNDA_01622 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AFHCFNDA_01623 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
AFHCFNDA_01624 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
AFHCFNDA_01625 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
AFHCFNDA_01626 2.6e-135 soj D COG1192 ATPases involved in chromosome partitioning
AFHCFNDA_01627 4.3e-147 spo0J K Belongs to the ParB family
AFHCFNDA_01628 1.1e-107 yyaC S Sporulation protein YyaC
AFHCFNDA_01629 4.5e-57 4.2.1.103 K FR47-like protein
AFHCFNDA_01630 2.4e-168 yyaD S Membrane
AFHCFNDA_01631 2.3e-33 yyzM S protein conserved in bacteria
AFHCFNDA_01632 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFHCFNDA_01633 1.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
AFHCFNDA_01634 3.6e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
AFHCFNDA_01635 8.4e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
AFHCFNDA_01636 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AFHCFNDA_01637 1.2e-95 adaA 3.2.2.21 K Transcriptional regulator
AFHCFNDA_01638 4.5e-86 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFHCFNDA_01639 1.7e-139 xth 3.1.11.2 L exodeoxyribonuclease III
AFHCFNDA_01640 6.9e-170 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
AFHCFNDA_01641 5.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFHCFNDA_01642 3.5e-236 ydjK G Sugar (and other) transporter
AFHCFNDA_01643 1.3e-149 yyaK S CAAX protease self-immunity
AFHCFNDA_01644 1.6e-213 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
AFHCFNDA_01645 9.1e-167 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
AFHCFNDA_01646 2.8e-67 ynaF
AFHCFNDA_01647 2e-27
AFHCFNDA_01648 3.8e-103 S Alpha/beta hydrolase family
AFHCFNDA_01649 3.3e-19 cadC3 K transcriptional
AFHCFNDA_01650 1.8e-70 yjcF S Acetyltransferase (GNAT) domain
AFHCFNDA_01651 3.1e-75 yybA 2.3.1.57 K transcriptional
AFHCFNDA_01652 5.3e-148 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
AFHCFNDA_01653 1.6e-65 ydgJ K Winged helix DNA-binding domain
AFHCFNDA_01654 4.4e-112 drgA C nitroreductase
AFHCFNDA_01655 4.2e-54 ypaA S Protein of unknown function (DUF1304)
AFHCFNDA_01656 1.1e-146 G Major Facilitator Superfamily
AFHCFNDA_01657 1.9e-73 dinB S PFAM DinB family protein
AFHCFNDA_01658 1.1e-108 K FCD domain
AFHCFNDA_01659 1.5e-302 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
AFHCFNDA_01660 1e-265 sacB 2.4.1.10 GH68 M levansucrase activity
AFHCFNDA_01661 2.5e-150 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AFHCFNDA_01662 7.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
AFHCFNDA_01663 1.2e-64 ydeP3 K Transcriptional regulator
AFHCFNDA_01664 4.9e-79 cotF M Spore coat protein
AFHCFNDA_01666 2.5e-148 yybS S membrane
AFHCFNDA_01667 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
AFHCFNDA_01668 8.3e-73 rplI J binds to the 23S rRNA
AFHCFNDA_01669 1.9e-80 KLT COG0515 Serine threonine protein kinase
AFHCFNDA_01670 1.8e-116 S GlcNAc-PI de-N-acetylase
AFHCFNDA_01671 6e-220 M Glycosyltransferase Family 4
AFHCFNDA_01672 5.2e-231 S Carbamoyl-phosphate synthase L chain, ATP binding domain
AFHCFNDA_01673 5.5e-192 S Ecdysteroid kinase
AFHCFNDA_01674 2.1e-214 M Glycosyltransferase Family 4
AFHCFNDA_01675 2.3e-16 yycC K YycC-like protein
AFHCFNDA_01677 2.2e-25 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
AFHCFNDA_01678 6.1e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
AFHCFNDA_01679 2.5e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFHCFNDA_01680 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFHCFNDA_01685 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_01686 0.0 vicK 2.7.13.3 T Histidine kinase
AFHCFNDA_01687 8.2e-257 yycH S protein conserved in bacteria
AFHCFNDA_01688 8.6e-148 yycI S protein conserved in bacteria
AFHCFNDA_01689 6.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
AFHCFNDA_01690 3.4e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFHCFNDA_01691 1.9e-63 S Peptidase propeptide and YPEB domain
AFHCFNDA_01692 6.5e-93 K PFAM response regulator receiver
AFHCFNDA_01693 3.7e-244 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
AFHCFNDA_01694 8.4e-197 S Major Facilitator Superfamily
AFHCFNDA_01695 4.7e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
AFHCFNDA_01696 1.3e-42 sdpR K transcriptional
AFHCFNDA_01697 1.6e-61 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
AFHCFNDA_01698 8.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
AFHCFNDA_01699 1.5e-253 rocE E amino acid
AFHCFNDA_01700 8.2e-165 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
AFHCFNDA_01701 4.6e-197 S Histidine kinase
AFHCFNDA_01703 1.4e-81 yycN 2.3.1.128 K Acetyltransferase
AFHCFNDA_01704 9.3e-178 C oxidoreductases (related to aryl-alcohol dehydrogenases)
AFHCFNDA_01705 1.9e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
AFHCFNDA_01706 2.3e-207 yycP
AFHCFNDA_01709 7.9e-08 S YyzF-like protein
AFHCFNDA_01710 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AFHCFNDA_01711 0.0 L AAA ATPase domain
AFHCFNDA_01712 2.8e-290 3.6.4.12 L AAA domain
AFHCFNDA_01713 6.5e-19
AFHCFNDA_01714 4e-155 S Fusaric acid resistance protein-like
AFHCFNDA_01715 2.6e-156 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AFHCFNDA_01716 1.6e-82 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
AFHCFNDA_01717 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
AFHCFNDA_01718 4.9e-143 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
AFHCFNDA_01719 3.2e-78 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
AFHCFNDA_01720 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
AFHCFNDA_01724 6.9e-169 L Belongs to the 'phage' integrase family
AFHCFNDA_01725 2.5e-57 immA E IrrE N-terminal-like domain
AFHCFNDA_01726 9.3e-44 yvaO K Transcriptional
AFHCFNDA_01727 3e-13
AFHCFNDA_01729 1.5e-27 S Bacterial protein of unknown function (DUF961)
AFHCFNDA_01730 5.4e-227 ydcQ D Ftsk spoiiie family protein
AFHCFNDA_01731 1.7e-180 nicK L Replication initiation factor
AFHCFNDA_01735 1.4e-39 yddA
AFHCFNDA_01736 3.8e-124 yddB S Conjugative transposon protein TcpC
AFHCFNDA_01737 1.4e-24 yddC
AFHCFNDA_01738 6.7e-74 yddD S TcpE family
AFHCFNDA_01739 0.0 yddE S AAA-like domain
AFHCFNDA_01740 1.2e-36 S Domain of unknown function (DUF1874)
AFHCFNDA_01741 1.4e-206 yddG S maturation of SSU-rRNA
AFHCFNDA_01742 1e-158 yddH CBM50 M Lysozyme-like
AFHCFNDA_01743 2.7e-56 yddI
AFHCFNDA_01744 1.4e-36 S Domain of unknown function with cystatin-like fold (DUF4467)
AFHCFNDA_01745 5.7e-19
AFHCFNDA_01747 7e-71 S response regulator aspartate phosphatase
AFHCFNDA_01749 3.7e-139 I esterase
AFHCFNDA_01750 1.5e-47 ohrB O OsmC-like protein
AFHCFNDA_01751 2.8e-49 ohrR K Transcriptional regulator
AFHCFNDA_01752 2.8e-13 S Domain of unknown function (DUF4367)
AFHCFNDA_01753 4.9e-54
AFHCFNDA_01754 8.2e-77 K Transcriptional regulator
AFHCFNDA_01755 2.3e-95 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AFHCFNDA_01756 5.1e-30 cspL K Cold shock
AFHCFNDA_01757 8.9e-111 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AFHCFNDA_01758 3.1e-101 S Protein of unknown function (DUF2812)
AFHCFNDA_01759 1.6e-49 K Transcriptional regulator PadR-like family
AFHCFNDA_01760 7.4e-237 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFHCFNDA_01761 5.9e-188 ydeG EGP Major facilitator superfamily
AFHCFNDA_01762 1.1e-50 S Patatin-like phospholipase
AFHCFNDA_01763 7e-45 S Patatin-like phospholipase
AFHCFNDA_01765 1.8e-102 ygaK C COG0277 FAD FMN-containing dehydrogenases
AFHCFNDA_01766 1.8e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFHCFNDA_01767 1.1e-151 czcD P COG1230 Co Zn Cd efflux system component
AFHCFNDA_01768 1.4e-160 S SNARE associated Golgi protein
AFHCFNDA_01769 5.8e-97 yrkC G Cupin domain
AFHCFNDA_01770 1.8e-82 yyaR K Acetyltransferase (GNAT) domain
AFHCFNDA_01771 6.6e-146 ydeE K AraC family transcriptional regulator
AFHCFNDA_01773 2.6e-186 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
AFHCFNDA_01774 7.1e-47 ydeH
AFHCFNDA_01775 1.3e-160 S Sodium Bile acid symporter family
AFHCFNDA_01776 5.1e-198 adhA 1.1.1.1 C alcohol dehydrogenase
AFHCFNDA_01777 5e-61 yraB K helix_turn_helix, mercury resistance
AFHCFNDA_01778 1.4e-218 mleN_2 C antiporter
AFHCFNDA_01779 4.6e-247 K helix_turn_helix gluconate operon transcriptional repressor
AFHCFNDA_01780 2.6e-101 paiB K Transcriptional regulator
AFHCFNDA_01781 7.4e-169 ydeR EGP Major facilitator Superfamily
AFHCFNDA_01782 1.8e-99 ydeS K Transcriptional regulator
AFHCFNDA_01783 5.7e-150 ydeK EG -transporter
AFHCFNDA_01784 9e-251 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFHCFNDA_01785 2.6e-46 yraD M Spore coat protein
AFHCFNDA_01786 3.1e-24 yraE
AFHCFNDA_01787 3.7e-218 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
AFHCFNDA_01788 8.4e-63 yraF M Spore coat protein
AFHCFNDA_01789 8.4e-35 yraG
AFHCFNDA_01790 2.3e-35 ydfJ S drug exporters of the RND superfamily
AFHCFNDA_01791 1.2e-126 puuD S Peptidase C26
AFHCFNDA_01792 4.6e-222 expZ S ABC transporter
AFHCFNDA_01793 4.3e-46 expZ S ABC transporter
AFHCFNDA_01794 3.6e-91 ynaD J Acetyltransferase (GNAT) domain
AFHCFNDA_01795 1.5e-147 S Uncharacterized protein conserved in bacteria (DUF2179)
AFHCFNDA_01796 2.5e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
AFHCFNDA_01797 2e-206 tcaB EGP Major facilitator Superfamily
AFHCFNDA_01798 2.8e-219 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFHCFNDA_01799 6.2e-154 K Helix-turn-helix XRE-family like proteins
AFHCFNDA_01800 1.1e-122 ydhB S membrane transporter protein
AFHCFNDA_01801 2e-77 bltD 2.3.1.57 K FR47-like protein
AFHCFNDA_01802 2.6e-141 bltR K helix_turn_helix, mercury resistance
AFHCFNDA_01803 3e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
AFHCFNDA_01804 9.3e-107 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
AFHCFNDA_01805 7.5e-105 S Alpha/beta hydrolase family
AFHCFNDA_01806 5.7e-165 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
AFHCFNDA_01807 1.3e-112 ydhC K FCD
AFHCFNDA_01808 1.2e-55 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
AFHCFNDA_01809 2.5e-81 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
AFHCFNDA_01810 3.4e-27 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
AFHCFNDA_01812 2.5e-245 pbpE V Beta-lactamase
AFHCFNDA_01814 1.2e-97 ydhK M Protein of unknown function (DUF1541)
AFHCFNDA_01815 3.2e-193 pbuE EGP Major facilitator Superfamily
AFHCFNDA_01816 3.1e-130 ydhQ K UTRA
AFHCFNDA_01817 2.1e-112 K FCD
AFHCFNDA_01818 8.2e-208 yeaN P COG2807 Cyanate permease
AFHCFNDA_01819 1.1e-47 sugE P Small Multidrug Resistance protein
AFHCFNDA_01820 3.1e-48 ykkC P Small Multidrug Resistance protein
AFHCFNDA_01821 2e-98 yvdT K Transcriptional regulator
AFHCFNDA_01822 8.2e-293 yveA E amino acid
AFHCFNDA_01823 1.4e-161 ydhU P Catalase
AFHCFNDA_01824 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
AFHCFNDA_01825 1.6e-177 yhfP 1.1.1.1 C Quinone oxidoreductase
AFHCFNDA_01826 5.4e-75 yjhE S Phage tail protein
AFHCFNDA_01827 1.4e-73 K Integron-associated effector binding protein
AFHCFNDA_01828 3.4e-156 K helix_turn_helix, Deoxyribose operon repressor
AFHCFNDA_01829 1e-235 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
AFHCFNDA_01830 9e-186 G Major royal jelly protein
AFHCFNDA_01831 8.9e-284 ahpF O Alkyl hydroperoxide reductase
AFHCFNDA_01832 9.4e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
AFHCFNDA_01833 3.6e-43 E Ring-cleavage extradiol dioxygenase
AFHCFNDA_01834 6e-65 E Ring-cleavage extradiol dioxygenase
AFHCFNDA_01835 2.2e-65 yxaI S membrane protein domain
AFHCFNDA_01836 1.1e-198 EGP Major facilitator Superfamily
AFHCFNDA_01837 4.3e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
AFHCFNDA_01838 2.7e-57 S Family of unknown function (DUF5391)
AFHCFNDA_01839 3.2e-138 S PQQ-like domain
AFHCFNDA_01840 4.9e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
AFHCFNDA_01841 1.4e-209 yxbF K Bacterial regulatory proteins, tetR family
AFHCFNDA_01842 1.2e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
AFHCFNDA_01843 3.5e-192 desK 2.7.13.3 T Histidine kinase
AFHCFNDA_01844 1.6e-100 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFHCFNDA_01845 2.5e-147 IQ Enoyl-(Acyl carrier protein) reductase
AFHCFNDA_01846 0.0 htpG O Molecular chaperone. Has ATPase activity
AFHCFNDA_01847 4.8e-244 csbC EGP Major facilitator Superfamily
AFHCFNDA_01848 4.4e-169 iolS C Aldo keto reductase
AFHCFNDA_01849 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
AFHCFNDA_01850 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
AFHCFNDA_01851 8.7e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
AFHCFNDA_01852 4.7e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
AFHCFNDA_01853 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
AFHCFNDA_01854 1.8e-172 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
AFHCFNDA_01855 2e-228 iolF EGP Major facilitator Superfamily
AFHCFNDA_01856 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
AFHCFNDA_01857 6.8e-164 iolH G Xylose isomerase-like TIM barrel
AFHCFNDA_01858 1.4e-145 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
AFHCFNDA_01859 4.6e-152 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
AFHCFNDA_01860 3e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_01861 9.6e-175 T PhoQ Sensor
AFHCFNDA_01862 1.4e-136 yxdL V ABC transporter, ATP-binding protein
AFHCFNDA_01863 0.0 yxdM V ABC transporter (permease)
AFHCFNDA_01864 2.7e-55 yxeA S Protein of unknown function (DUF1093)
AFHCFNDA_01865 1.2e-169 fhuD P Periplasmic binding protein
AFHCFNDA_01866 2.7e-35
AFHCFNDA_01867 7.9e-21 yxeD
AFHCFNDA_01872 2.1e-146 yidA S hydrolases of the HAD superfamily
AFHCFNDA_01873 5.3e-170 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
AFHCFNDA_01874 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AFHCFNDA_01875 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFHCFNDA_01876 3.3e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
AFHCFNDA_01877 4.3e-248 lysP E amino acid
AFHCFNDA_01878 1e-168 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
AFHCFNDA_01879 9.4e-231 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
AFHCFNDA_01880 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AFHCFNDA_01881 1.1e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
AFHCFNDA_01882 8.5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
AFHCFNDA_01883 3.4e-266 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
AFHCFNDA_01884 3.3e-197 S AIPR protein
AFHCFNDA_01885 3.4e-82 S Putative PD-(D/E)XK family member, (DUF4420)
AFHCFNDA_01886 2e-262 L Z1 domain
AFHCFNDA_01887 9.7e-163 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
AFHCFNDA_01888 2e-146 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
AFHCFNDA_01889 1.7e-46 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
AFHCFNDA_01890 6.8e-307 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFHCFNDA_01891 1.1e-275 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFHCFNDA_01892 9.2e-72 yxiE T Belongs to the universal stress protein A family
AFHCFNDA_01893 1.5e-142 yxxF EG EamA-like transporter family
AFHCFNDA_01894 2.2e-196 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
AFHCFNDA_01896 2.6e-57 yxxG
AFHCFNDA_01897 9.9e-65 yxiG
AFHCFNDA_01898 5.6e-77
AFHCFNDA_01899 3.9e-111
AFHCFNDA_01900 5.8e-14 S YxiJ-like protein
AFHCFNDA_01901 1.4e-21
AFHCFNDA_01903 3.4e-253 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
AFHCFNDA_01906 1.6e-08
AFHCFNDA_01909 1.2e-127 pdaB 3.5.1.104 G Polysaccharide deacetylase
AFHCFNDA_01910 1.7e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
AFHCFNDA_01911 1.7e-75 gerD
AFHCFNDA_01912 2.5e-192 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
AFHCFNDA_01913 2.4e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFHCFNDA_01914 3.6e-76 ybaK S Protein of unknown function (DUF2521)
AFHCFNDA_01915 2.7e-140 ybaJ Q Methyltransferase domain
AFHCFNDA_01916 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
AFHCFNDA_01917 7.1e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AFHCFNDA_01918 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
AFHCFNDA_01919 1.9e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFHCFNDA_01920 1.2e-144 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFHCFNDA_01921 1.4e-153 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AFHCFNDA_01922 4.7e-58 rplQ J Ribosomal protein L17
AFHCFNDA_01923 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFHCFNDA_01924 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AFHCFNDA_01925 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFHCFNDA_01926 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
AFHCFNDA_01927 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AFHCFNDA_01928 2.6e-140 map 3.4.11.18 E Methionine aminopeptidase
AFHCFNDA_01929 9.8e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
AFHCFNDA_01930 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
AFHCFNDA_01931 4.1e-72 rplO J binds to the 23S rRNA
AFHCFNDA_01932 1.9e-23 rpmD J Ribosomal protein L30
AFHCFNDA_01933 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AFHCFNDA_01934 2.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AFHCFNDA_01935 1.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AFHCFNDA_01936 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AFHCFNDA_01937 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFHCFNDA_01938 3.9e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFHCFNDA_01939 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AFHCFNDA_01940 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AFHCFNDA_01941 1.8e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AFHCFNDA_01942 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
AFHCFNDA_01943 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AFHCFNDA_01944 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AFHCFNDA_01945 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AFHCFNDA_01946 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AFHCFNDA_01947 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFHCFNDA_01948 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
AFHCFNDA_01949 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
AFHCFNDA_01950 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AFHCFNDA_01951 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
AFHCFNDA_01952 2.6e-172 ybaC 3.4.11.5 S Alpha/beta hydrolase family
AFHCFNDA_01953 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFHCFNDA_01954 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AFHCFNDA_01955 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
AFHCFNDA_01956 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AFHCFNDA_01957 2.7e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
AFHCFNDA_01958 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFHCFNDA_01959 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AFHCFNDA_01960 4.8e-108 rsmC 2.1.1.172 J Methyltransferase
AFHCFNDA_01961 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
AFHCFNDA_01962 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AFHCFNDA_01963 2.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
AFHCFNDA_01964 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AFHCFNDA_01965 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
AFHCFNDA_01966 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
AFHCFNDA_01967 4.4e-115 sigH K Belongs to the sigma-70 factor family
AFHCFNDA_01968 1.8e-87 yacP S RNA-binding protein containing a PIN domain
AFHCFNDA_01969 1.8e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFHCFNDA_01970 1.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
AFHCFNDA_01971 1.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
AFHCFNDA_01972 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
AFHCFNDA_01973 4.2e-275 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFHCFNDA_01974 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
AFHCFNDA_01975 1.8e-122 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
AFHCFNDA_01976 5.2e-185 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
AFHCFNDA_01977 2.7e-194 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
AFHCFNDA_01978 1.9e-253 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AFHCFNDA_01979 0.0 clpC O Belongs to the ClpA ClpB family
AFHCFNDA_01980 2.7e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
AFHCFNDA_01981 1.1e-60 mcsA 2.7.14.1 S protein with conserved CXXC pairs
AFHCFNDA_01982 7.5e-77 ctsR K Belongs to the CtsR family
AFHCFNDA_01983 4.2e-29 csfB S Inhibitor of sigma-G Gin
AFHCFNDA_01984 1.1e-99 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
AFHCFNDA_01985 2.6e-176 yaaN P Belongs to the TelA family
AFHCFNDA_01986 1.9e-256 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
AFHCFNDA_01987 7.8e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFHCFNDA_01988 7.5e-55 yaaQ S protein conserved in bacteria
AFHCFNDA_01989 3.8e-70 yaaR S protein conserved in bacteria
AFHCFNDA_01990 8.5e-179 holB 2.7.7.7 L DNA polymerase III
AFHCFNDA_01991 1.1e-144 yaaT S stage 0 sporulation protein
AFHCFNDA_01992 5e-36 yabA L Involved in initiation control of chromosome replication
AFHCFNDA_01993 1.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
AFHCFNDA_01994 5.2e-47 yazA L endonuclease containing a URI domain
AFHCFNDA_01995 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AFHCFNDA_01996 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
AFHCFNDA_01997 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFHCFNDA_01998 2.2e-142 tatD L hydrolase, TatD
AFHCFNDA_01999 4e-216 rpfB GH23 T protein conserved in bacteria
AFHCFNDA_02000 2.3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
AFHCFNDA_02001 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
AFHCFNDA_02002 8.2e-125 yabG S peptidase
AFHCFNDA_02003 7.8e-39 veg S protein conserved in bacteria
AFHCFNDA_02004 2.9e-27 sspF S DNA topological change
AFHCFNDA_02005 7.8e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AFHCFNDA_02006 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
AFHCFNDA_02007 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
AFHCFNDA_02008 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
AFHCFNDA_02009 1.7e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AFHCFNDA_02010 2.7e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFHCFNDA_02011 2.8e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AFHCFNDA_02012 1.2e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
AFHCFNDA_02013 6.9e-39 yabK S Peptide ABC transporter permease
AFHCFNDA_02014 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AFHCFNDA_02015 2.6e-89 spoVT K stage V sporulation protein
AFHCFNDA_02016 5.8e-270 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFHCFNDA_02017 7e-270 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
AFHCFNDA_02018 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
AFHCFNDA_02019 1.9e-49 yabP S Sporulation protein YabP
AFHCFNDA_02020 8.7e-100 yabQ S spore cortex biosynthesis protein
AFHCFNDA_02021 9.2e-57 divIC D Septum formation initiator
AFHCFNDA_02022 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
AFHCFNDA_02025 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
AFHCFNDA_02026 1.2e-121 yabS S protein containing a von Willebrand factor type A (vWA) domain
AFHCFNDA_02027 9.2e-181 KLT serine threonine protein kinase
AFHCFNDA_02028 2.1e-263 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
AFHCFNDA_02029 2.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
AFHCFNDA_02030 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFHCFNDA_02031 5.5e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AFHCFNDA_02032 1.2e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AFHCFNDA_02033 5.7e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
AFHCFNDA_02034 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
AFHCFNDA_02035 1.2e-263 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFHCFNDA_02036 5.7e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
AFHCFNDA_02037 1.6e-149 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
AFHCFNDA_02038 9.1e-153 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AFHCFNDA_02039 2.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AFHCFNDA_02040 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AFHCFNDA_02041 7.1e-28 yazB K transcriptional
AFHCFNDA_02042 1.6e-180 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AFHCFNDA_02043 1.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
AFHCFNDA_02044 4.8e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
AFHCFNDA_02045 1.8e-142 licT K transcriptional antiterminator
AFHCFNDA_02046 3.8e-136 exoK GH16 M licheninase activity
AFHCFNDA_02047 6.8e-221 citH C Citrate transporter
AFHCFNDA_02048 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
AFHCFNDA_02049 2.2e-181 L DNA synthesis involved in DNA repair
AFHCFNDA_02050 2.8e-45 yxiS
AFHCFNDA_02051 6e-67 T Domain of unknown function (DUF4163)
AFHCFNDA_02052 6.8e-208 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AFHCFNDA_02053 1.8e-143 rlmA 2.1.1.187 Q Methyltransferase domain
AFHCFNDA_02054 9.4e-214 yxjG 2.1.1.14 E Methionine synthase
AFHCFNDA_02055 3e-81 yxjI S LURP-one-related
AFHCFNDA_02058 2.6e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
AFHCFNDA_02059 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
AFHCFNDA_02060 9.7e-83 yxkC S Domain of unknown function (DUF4352)
AFHCFNDA_02062 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
AFHCFNDA_02063 2e-155 lrp QT PucR C-terminal helix-turn-helix domain
AFHCFNDA_02064 1.5e-203 msmK P Belongs to the ABC transporter superfamily
AFHCFNDA_02065 1.2e-149 yxkH G Polysaccharide deacetylase
AFHCFNDA_02066 5.2e-211 cimH C COG3493 Na citrate symporter
AFHCFNDA_02067 3.8e-265 cydA 1.10.3.14 C oxidase, subunit
AFHCFNDA_02068 5.7e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
AFHCFNDA_02069 6.4e-307 cydD V ATP-binding
AFHCFNDA_02070 4.8e-286 cydD V ATP-binding protein
AFHCFNDA_02071 5.3e-150 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AFHCFNDA_02072 7e-248 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
AFHCFNDA_02073 2e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
AFHCFNDA_02074 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
AFHCFNDA_02075 6.9e-206 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
AFHCFNDA_02076 1.5e-177 manA 5.3.1.8 G mannose-6-phosphate isomerase
AFHCFNDA_02077 1.1e-161 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
AFHCFNDA_02078 1.8e-278 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFHCFNDA_02079 1.8e-224 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFHCFNDA_02080 1.9e-47 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
AFHCFNDA_02081 4.9e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
AFHCFNDA_02082 3.9e-224 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AFHCFNDA_02083 1.2e-50 arsR K transcriptional
AFHCFNDA_02084 2.2e-165 cbrA3 P Periplasmic binding protein
AFHCFNDA_02085 3.3e-178 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_02086 2.9e-169 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_02087 5.2e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
AFHCFNDA_02088 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
AFHCFNDA_02089 7.5e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
AFHCFNDA_02090 1.2e-244 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFHCFNDA_02091 6.2e-49 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
AFHCFNDA_02092 2.3e-248 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
AFHCFNDA_02093 5.5e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
AFHCFNDA_02094 5.6e-193 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
AFHCFNDA_02095 5.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_02096 6.5e-226 dltB M membrane protein involved in D-alanine export
AFHCFNDA_02097 9e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_02098 4.7e-12 S D-Ala-teichoic acid biosynthesis protein
AFHCFNDA_02099 1.9e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
AFHCFNDA_02100 2.9e-116 ywaC 2.7.6.5 S protein conserved in bacteria
AFHCFNDA_02102 1.6e-160 gspA M General stress
AFHCFNDA_02103 7.8e-252 epr 3.4.21.62 O Belongs to the peptidase S8 family
AFHCFNDA_02104 1.6e-241 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
AFHCFNDA_02105 2.9e-66 ywbC 4.4.1.5 E glyoxalase
AFHCFNDA_02106 4.9e-221 ywbD 2.1.1.191 J Methyltransferase
AFHCFNDA_02107 7.1e-156 yjfC O Predicted Zn-dependent protease (DUF2268)
AFHCFNDA_02108 1.8e-128 mta K transcriptional
AFHCFNDA_02109 1.5e-26 ywbE S Uncharacterized conserved protein (DUF2196)
AFHCFNDA_02110 2.2e-109 ywbG M effector of murein hydrolase
AFHCFNDA_02111 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
AFHCFNDA_02112 2.6e-150 ywbI K Transcriptional regulator
AFHCFNDA_02113 4.8e-127 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AFHCFNDA_02114 1.8e-108 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
AFHCFNDA_02115 3.6e-194 P COG0672 High-affinity Fe2 Pb2 permease
AFHCFNDA_02116 2.4e-132 ycdO P periplasmic lipoprotein involved in iron transport
AFHCFNDA_02117 2.9e-232 ywbN P Dyp-type peroxidase family protein
AFHCFNDA_02118 6.3e-108 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
AFHCFNDA_02119 6.8e-119 S Streptomycin biosynthesis protein StrF
AFHCFNDA_02120 8.3e-125 H Methionine biosynthesis protein MetW
AFHCFNDA_02122 1.1e-96 ywcC K Bacterial regulatory proteins, tetR family
AFHCFNDA_02123 9.6e-60 gtcA S GtrA-like protein
AFHCFNDA_02124 2.1e-208 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFHCFNDA_02125 6.4e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
AFHCFNDA_02126 8.4e-27 ywzA S membrane
AFHCFNDA_02127 1.6e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
AFHCFNDA_02128 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AFHCFNDA_02129 2.3e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
AFHCFNDA_02130 1.6e-61 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
AFHCFNDA_02131 3.9e-31 ywcE S Required for proper spore morphogenesis. Important for spore germination
AFHCFNDA_02132 6.3e-68 ysnE K acetyltransferase
AFHCFNDA_02133 1.8e-207 rodA D Belongs to the SEDS family
AFHCFNDA_02134 6.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
AFHCFNDA_02135 2.1e-32 S Stress responsive A/B Barrel Domain
AFHCFNDA_02136 3.2e-42 S Ketosteroid isomerase-related protein
AFHCFNDA_02137 4e-126 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_02138 2.7e-118 M1-869 K WYL domain
AFHCFNDA_02139 6.4e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFHCFNDA_02140 0.0 vpr O Belongs to the peptidase S8 family
AFHCFNDA_02142 7e-150 sacT K transcriptional antiterminator
AFHCFNDA_02143 7.8e-247 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
AFHCFNDA_02144 1.7e-268 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
AFHCFNDA_02145 1.5e-20 ywdA
AFHCFNDA_02146 1.9e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AFHCFNDA_02148 9.2e-147 ywdF GT2,GT4 S Glycosyltransferase like family 2
AFHCFNDA_02149 5.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AFHCFNDA_02150 5.4e-36 ywdI S Family of unknown function (DUF5327)
AFHCFNDA_02151 5.6e-226 ywdJ F Xanthine uracil
AFHCFNDA_02152 5e-55 ywdK S small membrane protein
AFHCFNDA_02153 1.6e-62 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
AFHCFNDA_02154 9.4e-141 spsA M Spore Coat
AFHCFNDA_02155 2.7e-258 spsB M Capsule polysaccharide biosynthesis protein
AFHCFNDA_02156 1e-215 spsC E Belongs to the DegT DnrJ EryC1 family
AFHCFNDA_02157 6.6e-151 spsD 2.3.1.210 K Spore Coat
AFHCFNDA_02158 1.4e-209 spsE 2.5.1.56 M acid synthase
AFHCFNDA_02159 2.6e-124 spsF M Spore Coat
AFHCFNDA_02160 1.3e-166 spsG M Spore Coat
AFHCFNDA_02161 4.5e-132 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AFHCFNDA_02162 1e-176 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
AFHCFNDA_02163 5.6e-155 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
AFHCFNDA_02164 1.3e-84 spsL 5.1.3.13 M Spore Coat
AFHCFNDA_02165 2.6e-61
AFHCFNDA_02166 1.1e-245 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
AFHCFNDA_02167 6e-269 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
AFHCFNDA_02168 0.0 rocB E arginine degradation protein
AFHCFNDA_02169 4.2e-256 lysP E amino acid
AFHCFNDA_02170 8.8e-170 tcaB EGP Major facilitator Superfamily
AFHCFNDA_02171 5.8e-217 ywfA EGP Major facilitator Superfamily
AFHCFNDA_02172 1.4e-110 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
AFHCFNDA_02173 1.1e-135 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
AFHCFNDA_02174 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_02175 8e-263 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
AFHCFNDA_02176 4.7e-208 bacE EGP Major facilitator Superfamily
AFHCFNDA_02177 4.9e-229 ywfG 2.6.1.83 E Aminotransferase class I and II
AFHCFNDA_02178 8.9e-139 IQ Enoyl-(Acyl carrier protein) reductase
AFHCFNDA_02180 1.3e-14 K Helix-turn-helix XRE-family like proteins
AFHCFNDA_02181 4.8e-145 ywfI C May function as heme-dependent peroxidase
AFHCFNDA_02182 8.1e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
AFHCFNDA_02183 6.7e-152 MA20_14895 S Conserved hypothetical protein 698
AFHCFNDA_02184 1.3e-154 cysL K Transcriptional regulator
AFHCFNDA_02185 2e-155 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
AFHCFNDA_02187 4.2e-164
AFHCFNDA_02190 1.1e-162 yhcI S ABC transporter (permease)
AFHCFNDA_02191 2.2e-152 V ABC transporter, ATP-binding protein
AFHCFNDA_02192 4e-85 S membrane
AFHCFNDA_02193 4.1e-50 padR K PadR family transcriptional regulator
AFHCFNDA_02194 1.6e-103 rsfA_1
AFHCFNDA_02195 6.9e-36 ywzC S Belongs to the UPF0741 family
AFHCFNDA_02196 9e-253 ywfO S COG1078 HD superfamily phosphohydrolases
AFHCFNDA_02197 1.7e-87 ywgA 2.1.1.72, 3.1.21.3
AFHCFNDA_02198 4.9e-241 yhdG_1 E C-terminus of AA_permease
AFHCFNDA_02199 9.8e-68 ywhA K Transcriptional regulator
AFHCFNDA_02200 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
AFHCFNDA_02201 8.1e-117 ywhC S Peptidase family M50
AFHCFNDA_02202 5.1e-90 ywhD S YwhD family
AFHCFNDA_02203 3e-72
AFHCFNDA_02204 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFHCFNDA_02205 1.6e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AFHCFNDA_02206 2.3e-167 speB 3.5.3.11 E Belongs to the arginase family
AFHCFNDA_02208 5.8e-78 S aspartate phosphatase
AFHCFNDA_02209 1.2e-189 ywhL CO amine dehydrogenase activity
AFHCFNDA_02211 1.5e-71 ywiB S protein conserved in bacteria
AFHCFNDA_02212 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
AFHCFNDA_02213 4.3e-209 narK P COG2223 Nitrate nitrite transporter
AFHCFNDA_02214 1.4e-125 fnr K helix_turn_helix, cAMP Regulatory protein
AFHCFNDA_02215 1.6e-126 ywiC S YwiC-like protein
AFHCFNDA_02216 8.7e-20 arfM T cyclic nucleotide binding
AFHCFNDA_02217 4.3e-19 arfM T cyclic nucleotide binding
AFHCFNDA_02218 2.7e-205 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFHCFNDA_02219 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFHCFNDA_02220 3.8e-292 narH 1.7.5.1 C Nitrate reductase, beta
AFHCFNDA_02221 4e-85 narJ 1.7.5.1 C nitrate reductase
AFHCFNDA_02222 1.4e-116 narI 1.7.5.1 C nitrate reductase, gamma
AFHCFNDA_02223 2.7e-288 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFHCFNDA_02224 0.0 ywjA V ABC transporter
AFHCFNDA_02225 9.3e-43 ywjC
AFHCFNDA_02226 2.1e-174 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
AFHCFNDA_02227 1.1e-201 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
AFHCFNDA_02228 0.0 fadF C COG0247 Fe-S oxidoreductase
AFHCFNDA_02229 7.1e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
AFHCFNDA_02230 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
AFHCFNDA_02231 1.8e-90 ywjG S Domain of unknown function (DUF2529)
AFHCFNDA_02232 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
AFHCFNDA_02233 2.7e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
AFHCFNDA_02234 7.1e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AFHCFNDA_02235 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFHCFNDA_02236 1.1e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
AFHCFNDA_02237 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AFHCFNDA_02238 1.1e-32 rpmE J Binds the 23S rRNA
AFHCFNDA_02239 5.6e-101 tdk 2.7.1.21 F thymidine kinase
AFHCFNDA_02240 0.0 sfcA 1.1.1.38 C malic enzyme
AFHCFNDA_02241 1.1e-151 ywkB S Membrane transport protein
AFHCFNDA_02242 2.7e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
AFHCFNDA_02243 2.4e-65 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFHCFNDA_02244 2.6e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AFHCFNDA_02245 5.9e-152 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
AFHCFNDA_02247 9.7e-59 ywlA S Uncharacterised protein family (UPF0715)
AFHCFNDA_02248 9.2e-116 spoIIR S stage II sporulation protein R
AFHCFNDA_02249 3.7e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
AFHCFNDA_02250 3.8e-185 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
AFHCFNDA_02251 2.4e-85 mntP P Probably functions as a manganese efflux pump
AFHCFNDA_02252 1.1e-72 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AFHCFNDA_02253 4.6e-79 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
AFHCFNDA_02254 3.2e-95 ywlG S Belongs to the UPF0340 family
AFHCFNDA_02255 9.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFHCFNDA_02256 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AFHCFNDA_02257 2.8e-61 atpI S ATP synthase
AFHCFNDA_02258 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
AFHCFNDA_02259 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFHCFNDA_02260 3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AFHCFNDA_02261 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AFHCFNDA_02262 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AFHCFNDA_02263 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AFHCFNDA_02264 1e-265 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AFHCFNDA_02265 5.3e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
AFHCFNDA_02266 4.3e-88 ywmA
AFHCFNDA_02267 6.2e-32 ywzB S membrane
AFHCFNDA_02268 1.4e-130 ywmB S TATA-box binding
AFHCFNDA_02269 8.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AFHCFNDA_02270 1.2e-180 spoIID D Stage II sporulation protein D
AFHCFNDA_02271 1.3e-112 ywmC S protein containing a von Willebrand factor type A (vWA) domain
AFHCFNDA_02272 8.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
AFHCFNDA_02274 1e-142 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AFHCFNDA_02275 3.8e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFHCFNDA_02276 8.2e-93 S response regulator aspartate phosphatase
AFHCFNDA_02277 1.2e-80 ywmF S Peptidase M50
AFHCFNDA_02278 1.2e-09 csbD K CsbD-like
AFHCFNDA_02279 2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
AFHCFNDA_02280 5.5e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
AFHCFNDA_02281 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
AFHCFNDA_02282 6.1e-67 ywnA K Transcriptional regulator
AFHCFNDA_02283 3.7e-90 ywnB S NAD(P)H-binding
AFHCFNDA_02284 1.3e-50 ywnC S Family of unknown function (DUF5362)
AFHCFNDA_02285 8.6e-16 yqgA
AFHCFNDA_02286 1.2e-274 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AFHCFNDA_02287 1.3e-67 ywnF S Family of unknown function (DUF5392)
AFHCFNDA_02288 3.1e-11 ywnC S Family of unknown function (DUF5362)
AFHCFNDA_02289 3.9e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
AFHCFNDA_02290 2.7e-120 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
AFHCFNDA_02291 6.4e-67 ywnJ S VanZ like family
AFHCFNDA_02292 1.3e-99 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
AFHCFNDA_02293 1.1e-206 ftsW D Belongs to the SEDS family
AFHCFNDA_02294 1.7e-57 nrgB K Belongs to the P(II) protein family
AFHCFNDA_02295 3.9e-226 amt P Ammonium transporter
AFHCFNDA_02296 8.5e-99 phzA Q Isochorismatase family
AFHCFNDA_02297 9.8e-242 ywoD EGP Major facilitator superfamily
AFHCFNDA_02298 2.4e-270 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
AFHCFNDA_02299 4.1e-212 ywoG EGP Major facilitator Superfamily
AFHCFNDA_02300 1.1e-71 ywoH K transcriptional
AFHCFNDA_02301 1.8e-44 spoIIID K Stage III sporulation protein D
AFHCFNDA_02302 2.7e-180 mbl D Rod shape-determining protein
AFHCFNDA_02303 8e-127 flhO N flagellar basal body
AFHCFNDA_02304 1.5e-136 flhP N flagellar basal body
AFHCFNDA_02305 1.1e-192 S aspartate phosphatase
AFHCFNDA_02306 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
AFHCFNDA_02307 5.9e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
AFHCFNDA_02308 9.9e-68 ywpF S YwpF-like protein
AFHCFNDA_02309 2.5e-56 ywpG
AFHCFNDA_02310 5.4e-56 ssbB L Single-stranded DNA-binding protein
AFHCFNDA_02311 5.4e-136 glcR K DeoR C terminal sensor domain
AFHCFNDA_02312 7.2e-150 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
AFHCFNDA_02313 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
AFHCFNDA_02314 2.9e-301 ywqB S SWIM zinc finger
AFHCFNDA_02315 2.6e-15
AFHCFNDA_02316 1.2e-105 ywqC M biosynthesis protein
AFHCFNDA_02317 8.5e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
AFHCFNDA_02318 8.2e-137 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
AFHCFNDA_02319 4e-240 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFHCFNDA_02320 4.2e-144 ywqG S Domain of unknown function (DUF1963)
AFHCFNDA_02321 1.7e-17 S Domain of unknown function (DUF5082)
AFHCFNDA_02322 1.4e-35 ywqI S Family of unknown function (DUF5344)
AFHCFNDA_02323 4.1e-230 ywqJ S Pre-toxin TG
AFHCFNDA_02324 8.4e-59 S SUKH-4 immunity protein
AFHCFNDA_02325 3.6e-18
AFHCFNDA_02326 1.3e-73 S SMI1 / KNR4 family
AFHCFNDA_02327 4.9e-63
AFHCFNDA_02328 3.3e-102
AFHCFNDA_02329 1.9e-87 ywrA P COG2059 Chromate transport protein ChrA
AFHCFNDA_02330 2e-98 ywrB P Chromate transporter
AFHCFNDA_02331 3e-81 ywrC K Transcriptional regulator
AFHCFNDA_02332 1.6e-291 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
AFHCFNDA_02334 6.2e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFHCFNDA_02335 1.4e-06
AFHCFNDA_02336 8.5e-204 cotH M Spore Coat
AFHCFNDA_02337 1.5e-113 cotB
AFHCFNDA_02338 1.2e-115 ywrJ
AFHCFNDA_02339 1.1e-232 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AFHCFNDA_02340 7.1e-164 alsR K LysR substrate binding domain
AFHCFNDA_02341 9.6e-303 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
AFHCFNDA_02342 9e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
AFHCFNDA_02343 7.5e-89 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
AFHCFNDA_02344 3.9e-85 batE T Sh3 type 3 domain protein
AFHCFNDA_02345 3.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
AFHCFNDA_02346 3.5e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
AFHCFNDA_02347 8.4e-271 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
AFHCFNDA_02348 9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
AFHCFNDA_02349 6.5e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AFHCFNDA_02350 3.7e-174 rbsR K transcriptional
AFHCFNDA_02351 4.4e-113 gerKC S Spore germination B3/ GerAC like, C-terminal
AFHCFNDA_02352 1.5e-33 gerKC S Spore germination B3/ GerAC like, C-terminal
AFHCFNDA_02353 1.2e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
AFHCFNDA_02354 4.8e-143 yunE S membrane transporter protein
AFHCFNDA_02355 9.9e-168 yunF S Protein of unknown function DUF72
AFHCFNDA_02356 2.1e-55 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
AFHCFNDA_02357 2.7e-252 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
AFHCFNDA_02358 1.7e-293 pucR QT COG2508 Regulator of polyketide synthase expression
AFHCFNDA_02359 2.8e-65
AFHCFNDA_02360 1.4e-207 blt EGP Major facilitator Superfamily
AFHCFNDA_02361 1.2e-225 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
AFHCFNDA_02362 6.4e-224 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
AFHCFNDA_02363 3.7e-162 bsn L Ribonuclease
AFHCFNDA_02364 7e-198 msmX P Belongs to the ABC transporter superfamily
AFHCFNDA_02365 1.5e-132 yurK K UTRA
AFHCFNDA_02366 2.5e-158 yurL 2.7.1.218 G pfkB family carbohydrate kinase
AFHCFNDA_02367 2.4e-156 yurM P COG0395 ABC-type sugar transport system, permease component
AFHCFNDA_02368 2.2e-157 yurN G Binding-protein-dependent transport system inner membrane component
AFHCFNDA_02369 2.1e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
AFHCFNDA_02370 5.3e-181 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
AFHCFNDA_02371 5.4e-159 K helix_turn_helix, mercury resistance
AFHCFNDA_02372 1e-14
AFHCFNDA_02373 5.3e-77
AFHCFNDA_02375 3.8e-10 S Sporulation delaying protein SdpA
AFHCFNDA_02377 2.6e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
AFHCFNDA_02378 3.5e-197 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
AFHCFNDA_02379 3.4e-101 Q ubiE/COQ5 methyltransferase family
AFHCFNDA_02380 1.1e-72 yncE S Protein of unknown function (DUF2691)
AFHCFNDA_02381 1.9e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
AFHCFNDA_02382 8.7e-270 sufB O FeS cluster assembly
AFHCFNDA_02383 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
AFHCFNDA_02384 2.8e-232 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AFHCFNDA_02385 7e-245 sufD O assembly protein SufD
AFHCFNDA_02386 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
AFHCFNDA_02387 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AFHCFNDA_02388 4e-142 metQ P Belongs to the NlpA lipoprotein family
AFHCFNDA_02389 8.3e-93 metI P COG2011 ABC-type metal ion transport system, permease component
AFHCFNDA_02390 5.4e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFHCFNDA_02391 2.1e-55 yusD S SCP-2 sterol transfer family
AFHCFNDA_02392 5.2e-53 yusE CO Thioredoxin
AFHCFNDA_02393 9.7e-22 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
AFHCFNDA_02394 2.1e-38 yusG S Protein of unknown function (DUF2553)
AFHCFNDA_02395 5.5e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
AFHCFNDA_02396 1.8e-62 arsC 1.20.4.1 P Belongs to the ArsC family
AFHCFNDA_02397 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
AFHCFNDA_02398 1e-215 fadA 2.3.1.16 I Belongs to the thiolase family
AFHCFNDA_02399 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
AFHCFNDA_02401 3.9e-162 fadM E Proline dehydrogenase
AFHCFNDA_02402 3.5e-39
AFHCFNDA_02403 1.3e-51 yusN M Coat F domain
AFHCFNDA_02404 4.5e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
AFHCFNDA_02405 5.4e-284 yusP P Major facilitator superfamily
AFHCFNDA_02406 7.9e-277 cisA2 L Recombinase
AFHCFNDA_02407 2.9e-07 yrkD S protein conserved in bacteria
AFHCFNDA_02408 1.8e-104 yrkC G Cupin domain
AFHCFNDA_02410 1.9e-20 S response regulator aspartate phosphatase
AFHCFNDA_02411 3.4e-64 S Tetratricopeptide repeat
AFHCFNDA_02412 2.3e-29
AFHCFNDA_02413 5.4e-229 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
AFHCFNDA_02414 5e-27 yokK S SMI1 / KNR4 family
AFHCFNDA_02416 3.2e-59
AFHCFNDA_02418 7.9e-138 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
AFHCFNDA_02419 1.3e-67 S Bacteriophage holin family
AFHCFNDA_02420 2.2e-157 xepA
AFHCFNDA_02421 7.9e-21
AFHCFNDA_02422 1e-51 xkdW S XkdW protein
AFHCFNDA_02423 1.6e-218
AFHCFNDA_02424 1.8e-38
AFHCFNDA_02425 1.1e-96 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
AFHCFNDA_02426 1.8e-187 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
AFHCFNDA_02427 6.9e-69 xkdS S Protein of unknown function (DUF2634)
AFHCFNDA_02428 7.9e-177 yqbQ 3.2.1.96 G NLP P60 protein
AFHCFNDA_02429 2.9e-112 xkdP S Lysin motif
AFHCFNDA_02430 0.0 xkdO L Transglycosylase SLT domain
AFHCFNDA_02431 2.3e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
AFHCFNDA_02432 1.1e-78 2.7.7.49 L PFAM Reverse transcriptase (RNA-dependent DNA polymerase)
AFHCFNDA_02433 6.8e-114 2.7.7.49 L PFAM Reverse transcriptase (RNA-dependent DNA polymerase)
AFHCFNDA_02434 3.6e-76 xkdM S Phage tail tube protein
AFHCFNDA_02435 6.3e-252 xkdK S Phage tail sheath C-terminal domain
AFHCFNDA_02436 1.3e-24
AFHCFNDA_02437 1.9e-74
AFHCFNDA_02438 1.2e-86 S Bacteriophage HK97-gp10, putative tail-component
AFHCFNDA_02439 3.1e-62 yqbH S Domain of unknown function (DUF3599)
AFHCFNDA_02440 2.7e-67 S Protein of unknown function (DUF3199)
AFHCFNDA_02441 1.3e-45 S YqbF, hypothetical protein domain
AFHCFNDA_02442 3.2e-167 xkdG S Phage capsid family
AFHCFNDA_02443 3.1e-117 yqbD 2.1.1.72 L Putative phage serine protease XkdF
AFHCFNDA_02445 1.5e-148 S Phage Mu protein F like protein
AFHCFNDA_02446 8.6e-251 yqbA S portal protein
AFHCFNDA_02447 8.2e-27 yqbA S portal protein
AFHCFNDA_02448 4.2e-250 S phage terminase, large subunit
AFHCFNDA_02449 6.4e-76 yqaS L DNA packaging
AFHCFNDA_02450 5.9e-59
AFHCFNDA_02451 2e-07
AFHCFNDA_02454 2.1e-76 L Transposase
AFHCFNDA_02455 2.6e-75 S Beta protein
AFHCFNDA_02456 2.4e-54 S Psort location Cytoplasmic, score
AFHCFNDA_02457 1.1e-30 yqaO S Phage-like element PBSX protein XtrA
AFHCFNDA_02458 4.4e-71 rusA L Endodeoxyribonuclease RusA
AFHCFNDA_02460 2.6e-163 xkdC L IstB-like ATP binding protein
AFHCFNDA_02461 2.4e-114 3.1.3.16 L DnaD domain protein
AFHCFNDA_02462 5.1e-51 recT L RecT family
AFHCFNDA_02463 1.2e-06
AFHCFNDA_02464 1.5e-26 U TraM recognition site of TraD and TraG
AFHCFNDA_02466 4.1e-70 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AFHCFNDA_02467 3e-238 3.2.1.11 GH66 G Glycosyl hydrolase family 66
AFHCFNDA_02468 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
AFHCFNDA_02469 1.5e-109 istB2 L IstB-like ATP binding protein
AFHCFNDA_02471 7e-187 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
AFHCFNDA_02472 0.0 cstA T Carbon starvation protein
AFHCFNDA_02473 4.1e-245 glcF C Glycolate oxidase
AFHCFNDA_02474 8.8e-254 glcD 1.1.3.15 C FAD binding domain
AFHCFNDA_02475 4.8e-191 ysfB KT regulator
AFHCFNDA_02476 7.6e-32 sspI S Belongs to the SspI family
AFHCFNDA_02477 1.4e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFHCFNDA_02478 3.4e-194 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFHCFNDA_02479 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
AFHCFNDA_02480 1.5e-164 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFHCFNDA_02481 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AFHCFNDA_02482 2.3e-82 cvpA S membrane protein, required for colicin V production
AFHCFNDA_02483 0.0 polX L COG1796 DNA polymerase IV (family X)
AFHCFNDA_02484 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
AFHCFNDA_02485 4.7e-67 yshE S membrane
AFHCFNDA_02486 2e-115 ywbB S Protein of unknown function (DUF2711)
AFHCFNDA_02487 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
AFHCFNDA_02488 2.7e-103 fadR K Transcriptional regulator
AFHCFNDA_02489 3.6e-132 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
AFHCFNDA_02490 2.2e-137 etfB C Electron transfer flavoprotein
AFHCFNDA_02491 3e-176 etfA C Electron transfer flavoprotein
AFHCFNDA_02492 8.9e-297 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
AFHCFNDA_02493 2.5e-52 trxA O Belongs to the thioredoxin family
AFHCFNDA_02494 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
AFHCFNDA_02495 1.2e-211 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
AFHCFNDA_02496 3.5e-79 yslB S Protein of unknown function (DUF2507)
AFHCFNDA_02497 4.8e-108 sdhC C succinate dehydrogenase
AFHCFNDA_02498 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
AFHCFNDA_02499 3.9e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
AFHCFNDA_02500 2.1e-73 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
AFHCFNDA_02501 3.5e-39 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_02502 6.2e-137 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_02503 1.1e-62 hxlR K transcriptional
AFHCFNDA_02504 1.2e-101 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
AFHCFNDA_02505 1.3e-91 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
AFHCFNDA_02506 4.2e-77 nucA M Deoxyribonuclease NucA/NucB
AFHCFNDA_02507 9.7e-65 nin S Competence protein J (ComJ)
AFHCFNDA_02508 2.3e-286 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFHCFNDA_02509 3.5e-49 S Protein of unknown function (DUF2680)
AFHCFNDA_02510 5.2e-72 yckC S membrane
AFHCFNDA_02511 6.1e-174 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
AFHCFNDA_02512 3.4e-222 yciC S GTPases (G3E family)
AFHCFNDA_02513 2.7e-39 nasA P COG2223 Nitrate nitrite transporter
AFHCFNDA_02514 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFHCFNDA_02515 1.5e-55 nirD 1.7.1.15 P Nitrite reductase
AFHCFNDA_02516 9e-262 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
AFHCFNDA_02517 2.4e-184 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
AFHCFNDA_02518 3.7e-224 ycgP QT COG2508 Regulator of polyketide synthase expression
AFHCFNDA_02519 3.2e-243 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFHCFNDA_02520 2.9e-290 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
AFHCFNDA_02521 6.2e-168 ycgM E Proline dehydrogenase
AFHCFNDA_02522 7.6e-138 ycgL S Predicted nucleotidyltransferase
AFHCFNDA_02523 4e-181 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
AFHCFNDA_02524 3.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AFHCFNDA_02525 4.1e-221 G COG0477 Permeases of the major facilitator superfamily
AFHCFNDA_02526 3.8e-129 4.2.1.118 G Xylose isomerase-like TIM barrel
AFHCFNDA_02527 3.2e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
AFHCFNDA_02528 4.2e-112 ycgI S Domain of unknown function (DUF1989)
AFHCFNDA_02529 4.5e-239 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
AFHCFNDA_02530 3.1e-144 yqcI S YqcI/YcgG family
AFHCFNDA_02531 1.5e-58 ycgF E Lysine exporter protein LysE YggA
AFHCFNDA_02532 4.5e-42 ycgF E Lysine exporter protein LysE YggA
AFHCFNDA_02533 7.5e-59 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFHCFNDA_02534 1.6e-14 cisA2 L Recombinase
AFHCFNDA_02535 8.1e-151 smc L AAA ATPase domain
AFHCFNDA_02536 1e-40 IQ Enoyl-(Acyl carrier protein) reductase
AFHCFNDA_02537 3.3e-13 Q Non-ribosomal peptide synthetase modules and related proteins
AFHCFNDA_02538 2.9e-159 efpA EGP Major facilitator superfamily
AFHCFNDA_02539 4.3e-77 pabA 2.6.1.85, 4.1.3.27 EH TIGRFAM glutamine amidotransferase of anthranilate synthase
AFHCFNDA_02540 4.4e-181 trpE 4.1.3.27 EH Anthranilate synthase component I domain protein
AFHCFNDA_02541 1.2e-175 6.2.1.30 H phenylacetate-CoA ligase activity
AFHCFNDA_02542 0.0 Q AMP-binding enzyme C-terminal domain
AFHCFNDA_02543 1.7e-306 Q AMP-binding enzyme C-terminal domain
AFHCFNDA_02544 7.2e-124 S Winged helix DNA-binding domain
AFHCFNDA_02545 6.1e-204 glyA_1 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFHCFNDA_02546 3.3e-114 mchB Q Thioesterase involved in non-ribosomal peptide biosynthesis
AFHCFNDA_02548 4.1e-162 yobV9 K HTH domain
AFHCFNDA_02549 3.1e-105 yoaZ S DJ-1/PfpI family
AFHCFNDA_02550 6.4e-19
AFHCFNDA_02554 1.7e-20 S SMI1-KNR4 cell-wall
AFHCFNDA_02555 1e-13 xkdS S Protein of unknown function (DUF2634)
AFHCFNDA_02556 2.9e-109 5.1.1.13 M Belongs to the aspartate glutamate racemases family
AFHCFNDA_02557 1.1e-137 yvgN 1.1.1.346 S Reductase
AFHCFNDA_02558 3.2e-69 K MerR family transcriptional regulator
AFHCFNDA_02559 5.7e-16 xkdG S Phage capsid family
AFHCFNDA_02560 3.8e-83 yqaS L DNA packaging
AFHCFNDA_02561 8.2e-163 S Terminase RNAseH like domain
AFHCFNDA_02562 4.6e-157 S Phage portal protein, SPP1 Gp6-like
AFHCFNDA_02564 1.8e-48 S Domain of unknown function (DUF4355)
AFHCFNDA_02565 4.4e-123 S P22 coat protein - gene protein 5
AFHCFNDA_02567 7.8e-35 S Phage Mu protein F like protein
AFHCFNDA_02568 2.2e-17 S Phage gp6-like head-tail connector protein
AFHCFNDA_02569 1e-47
AFHCFNDA_02570 1.1e-25
AFHCFNDA_02571 4.8e-31
AFHCFNDA_02572 8e-103 Z012_02110 S Protein of unknown function (DUF3383)
AFHCFNDA_02573 1.4e-34
AFHCFNDA_02574 3.1e-15
AFHCFNDA_02575 1.5e-129 N phage tail tape measure protein
AFHCFNDA_02576 1e-40 3.5.1.28 M LysM domain
AFHCFNDA_02577 5.9e-29
AFHCFNDA_02578 3e-88
AFHCFNDA_02579 7.7e-26
AFHCFNDA_02580 5.1e-25 S Protein of unknown function (DUF2634)
AFHCFNDA_02581 3.2e-100 Z012_12235 S homolog of phage Mu protein gp47
AFHCFNDA_02582 7.8e-61
AFHCFNDA_02583 6.5e-51
AFHCFNDA_02585 4.8e-17 xkdX
AFHCFNDA_02586 5.4e-30 xhlA S Haemolysin XhlA
AFHCFNDA_02587 6.3e-28 xhlB S SPP1 phage holin
AFHCFNDA_02588 6e-75 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFHCFNDA_02589 3.5e-36 KLT Protein tyrosine kinase
AFHCFNDA_02591 8.5e-21 K Helix-turn-helix domain
AFHCFNDA_02592 1.8e-07 S Immunity protein 50
AFHCFNDA_02593 6.2e-131 A Pre-toxin TG
AFHCFNDA_02594 3.3e-102 S aspartate phosphatase
AFHCFNDA_02598 2.1e-178 gerKB E Spore germination protein
AFHCFNDA_02599 1.2e-184 gerKA EG Spore germination protein
AFHCFNDA_02600 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
AFHCFNDA_02601 2.3e-70 pgsC S biosynthesis protein
AFHCFNDA_02602 1.2e-216 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
AFHCFNDA_02603 3.8e-20 ywtC
AFHCFNDA_02604 8.6e-229 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
AFHCFNDA_02605 4.1e-29 yttA 2.7.13.3 S Pfam Transposase IS66
AFHCFNDA_02606 1.4e-153 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
AFHCFNDA_02607 1.1e-173 ywtF K Transcriptional regulator
AFHCFNDA_02608 1.6e-239 ywtG EGP Major facilitator Superfamily
AFHCFNDA_02609 4.4e-258 GT2,GT4 J Glycosyl transferase family 2
AFHCFNDA_02610 1.7e-171 gerAC S Spore germination protein
AFHCFNDA_02611 1.4e-190 gerBB E Spore germination protein
AFHCFNDA_02612 3.2e-251 gerBA EG Spore germination protein
AFHCFNDA_02613 1.4e-159 pmi 5.3.1.8 G mannose-6-phosphate isomerase
AFHCFNDA_02614 1.5e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AFHCFNDA_02615 7.6e-203 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AFHCFNDA_02616 1.4e-139 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
AFHCFNDA_02617 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
AFHCFNDA_02618 1.3e-258 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
AFHCFNDA_02619 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AFHCFNDA_02620 3.4e-136 tagG GM Transport permease protein
AFHCFNDA_02621 1e-178 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
AFHCFNDA_02622 2.1e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
AFHCFNDA_02623 1.2e-184 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
AFHCFNDA_02624 3.1e-138 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
AFHCFNDA_02625 1e-29
AFHCFNDA_02626 1.1e-303 lytB 3.5.1.28 D Stage II sporulation protein
AFHCFNDA_02627 6.7e-212 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
AFHCFNDA_02628 1.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
AFHCFNDA_02629 4.8e-255 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFHCFNDA_02630 1.4e-212 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
AFHCFNDA_02631 1.5e-242 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFHCFNDA_02632 5.4e-251 tuaE M Teichuronic acid biosynthesis protein
AFHCFNDA_02633 1.6e-107 tuaF M protein involved in exopolysaccharide biosynthesis
AFHCFNDA_02634 1.9e-141 tuaG GT2 M Glycosyltransferase like family 2
AFHCFNDA_02635 5.6e-225 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
AFHCFNDA_02636 1.4e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
AFHCFNDA_02637 4.2e-170 yvhJ K Transcriptional regulator
AFHCFNDA_02638 1e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
AFHCFNDA_02639 3.4e-179 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
AFHCFNDA_02640 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFHCFNDA_02641 8.1e-154 degV S protein conserved in bacteria
AFHCFNDA_02642 3.2e-248 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
AFHCFNDA_02643 8.2e-42 comFB S Late competence development protein ComFB
AFHCFNDA_02644 8.1e-72 yvyF S flagellar protein
AFHCFNDA_02645 1.3e-37 flgM KNU Negative regulator of flagellin synthesis
AFHCFNDA_02646 5.4e-78 flgN NOU FlgN protein
AFHCFNDA_02647 2.2e-271 flgK N flagellar hook-associated protein
AFHCFNDA_02648 7.4e-161 flgL N Belongs to the bacterial flagellin family
AFHCFNDA_02649 8.3e-78 yviE
AFHCFNDA_02650 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
AFHCFNDA_02651 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AFHCFNDA_02652 1.9e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AFHCFNDA_02653 9.5e-238 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AFHCFNDA_02654 7e-63 fliS N flagellar protein FliS
AFHCFNDA_02655 1.3e-09 fliT S bacterial-type flagellum organization
AFHCFNDA_02656 6.8e-68
AFHCFNDA_02657 4.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AFHCFNDA_02658 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
AFHCFNDA_02659 9.4e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AFHCFNDA_02660 1.5e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
AFHCFNDA_02661 5.2e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
AFHCFNDA_02662 2.3e-122 ftsE D cell division ATP-binding protein FtsE
AFHCFNDA_02663 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
AFHCFNDA_02664 6.9e-190 ywoF P Right handed beta helix region
AFHCFNDA_02665 3.8e-249 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
AFHCFNDA_02666 2.9e-54 swrA S Swarming motility protein
AFHCFNDA_02667 1.1e-217 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFHCFNDA_02669 4.5e-25 yuaB
AFHCFNDA_02670 6.5e-222 yvkA EGP Major facilitator Superfamily
AFHCFNDA_02671 1e-91 yvkB K Transcriptional regulator
AFHCFNDA_02672 0.0 yvkC 2.7.9.2 GT Phosphotransferase
AFHCFNDA_02673 7.6e-33 csbA S protein conserved in bacteria
AFHCFNDA_02674 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
AFHCFNDA_02675 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
AFHCFNDA_02676 3.6e-30 yvkN
AFHCFNDA_02677 4e-46 yvlA
AFHCFNDA_02678 5.6e-163 yvlB S Putative adhesin
AFHCFNDA_02679 9.6e-26 pspB KT PspC domain
AFHCFNDA_02680 9.1e-46 yvlD S Membrane
AFHCFNDA_02681 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
AFHCFNDA_02682 3.2e-101 yxaF K Transcriptional regulator
AFHCFNDA_02683 7.6e-132 yvoA K transcriptional
AFHCFNDA_02684 4.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
AFHCFNDA_02685 3.4e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
AFHCFNDA_02686 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AFHCFNDA_02687 3.4e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AFHCFNDA_02688 1.3e-111 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
AFHCFNDA_02689 6.9e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
AFHCFNDA_02690 7.2e-135 yvpB NU protein conserved in bacteria
AFHCFNDA_02691 9.4e-201 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AFHCFNDA_02692 1.4e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
AFHCFNDA_02693 1.7e-219 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AFHCFNDA_02694 8.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
AFHCFNDA_02695 1.4e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AFHCFNDA_02696 6.7e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AFHCFNDA_02697 1.2e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
AFHCFNDA_02698 2.2e-108 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
AFHCFNDA_02699 0.0 msbA2 3.6.3.44 V ABC transporter
AFHCFNDA_02700 4.4e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_02701 6.8e-182 sasA T Histidine kinase
AFHCFNDA_02702 4.2e-267 S COG0457 FOG TPR repeat
AFHCFNDA_02703 2.1e-117 usp CBM50 M protein conserved in bacteria
AFHCFNDA_02704 9.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
AFHCFNDA_02705 8.5e-87 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
AFHCFNDA_02706 3.3e-166 rapZ S Displays ATPase and GTPase activities
AFHCFNDA_02707 3.2e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
AFHCFNDA_02708 3.1e-170 whiA K May be required for sporulation
AFHCFNDA_02709 1.4e-35 crh G Phosphocarrier protein Chr
AFHCFNDA_02710 1.4e-68 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
AFHCFNDA_02711 4.3e-44 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
AFHCFNDA_02712 1.3e-76 M Ribonuclease
AFHCFNDA_02713 2.9e-179 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFHCFNDA_02714 4.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
AFHCFNDA_02715 5.8e-270 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
AFHCFNDA_02716 7.1e-50 yvdC S MazG nucleotide pyrophosphohydrolase domain
AFHCFNDA_02717 6.4e-102 yvdD 3.2.2.10 S Belongs to the LOG family
AFHCFNDA_02718 5.3e-89
AFHCFNDA_02719 8.3e-241 EGP Sugar (and other) transporter
AFHCFNDA_02720 3.7e-202 yraM S PrpF protein
AFHCFNDA_02721 7.2e-158 yraN K Transcriptional regulator
AFHCFNDA_02722 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
AFHCFNDA_02723 4.6e-177 scrR K transcriptional
AFHCFNDA_02724 7.8e-214 rafB P LacY proton/sugar symporter
AFHCFNDA_02725 2.8e-279 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
AFHCFNDA_02727 7.6e-33
AFHCFNDA_02728 1.7e-97 I Pfam Lipase (class 3)
AFHCFNDA_02729 4.9e-127 I Pfam Lipase (class 3)
AFHCFNDA_02730 4.8e-19 S Protein of unknown function (DUF1433)
AFHCFNDA_02731 5e-17 S Protein of unknown function (DUF1433)
AFHCFNDA_02732 6.1e-31 S Protein of unknown function (DUF1433)
AFHCFNDA_02733 1.2e-93 padC Q Phenolic acid decarboxylase
AFHCFNDA_02734 1e-82 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFHCFNDA_02735 3e-105 yyaS S Membrane
AFHCFNDA_02736 9.3e-74 S Metallo-beta-lactamase superfamily
AFHCFNDA_02737 1.7e-130 CH FAD binding domain
AFHCFNDA_02738 1.3e-85 ywjB H RibD C-terminal domain
AFHCFNDA_02740 6.5e-236 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
AFHCFNDA_02741 5.1e-78 slr K transcriptional
AFHCFNDA_02742 3.3e-116 ywqC M biosynthesis protein
AFHCFNDA_02743 2.1e-112 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
AFHCFNDA_02744 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
AFHCFNDA_02745 3.6e-213 epsD GT4 M Glycosyl transferase 4-like
AFHCFNDA_02746 8.6e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
AFHCFNDA_02747 1.1e-198 epsF GT4 M Glycosyl transferases group 1
AFHCFNDA_02748 1.4e-201 epsG S EpsG family
AFHCFNDA_02749 4.6e-191 epsH GT2 S Glycosyltransferase like family 2
AFHCFNDA_02750 2e-197 epsI GM pyruvyl transferase
AFHCFNDA_02751 2e-186 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
AFHCFNDA_02752 5.2e-268 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
AFHCFNDA_02753 1.8e-102 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
AFHCFNDA_02754 1.1e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
AFHCFNDA_02755 2.7e-216 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
AFHCFNDA_02756 1.9e-89 yvfF GM Exopolysaccharide biosynthesis protein
AFHCFNDA_02757 2.7e-32 yvfG S YvfG protein
AFHCFNDA_02758 8.8e-232 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
AFHCFNDA_02759 3.8e-296 yvfH C L-lactate permease
AFHCFNDA_02760 1.4e-117 yvfI K COG2186 Transcriptional regulators
AFHCFNDA_02761 2.1e-208 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFHCFNDA_02762 1.8e-133 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
AFHCFNDA_02763 1.7e-265 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
AFHCFNDA_02764 3.5e-129 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
AFHCFNDA_02765 2.3e-219 gntP EG COG2610 H gluconate symporter and related permeases
AFHCFNDA_02766 6.6e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
AFHCFNDA_02767 6.7e-148 ybbH_1 K RpiR family transcriptional regulator
AFHCFNDA_02769 1.2e-212 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
AFHCFNDA_02770 8.2e-152 yvbV EG EamA-like transporter family
AFHCFNDA_02771 1.7e-96 yvbU K Transcriptional regulator
AFHCFNDA_02772 1.1e-13 yvbU K Transcriptional regulator
AFHCFNDA_02773 1.2e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFHCFNDA_02774 6.7e-201 araR K transcriptional
AFHCFNDA_02775 2.8e-211 araE EGP Major facilitator Superfamily
AFHCFNDA_02776 2.3e-31 araE EGP Major facilitator Superfamily
AFHCFNDA_02777 8.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
AFHCFNDA_02778 4.8e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFHCFNDA_02779 1.6e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
AFHCFNDA_02780 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
AFHCFNDA_02781 6.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
AFHCFNDA_02782 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
AFHCFNDA_02783 7.3e-223 ywaD 3.4.11.10, 3.4.11.6 S PA domain
AFHCFNDA_02784 9.5e-250 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFHCFNDA_02785 7.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
AFHCFNDA_02786 1.4e-167 5.1.3.2 M GDP-mannose 4,6 dehydratase
AFHCFNDA_02787 2.8e-219 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AFHCFNDA_02788 2.4e-140 M Protein involved in cellulose biosynthesis
AFHCFNDA_02789 2.4e-141 C WbqC-like protein family
AFHCFNDA_02790 2e-123 S GlcNAc-PI de-N-acetylase
AFHCFNDA_02791 4.2e-172
AFHCFNDA_02792 7.8e-206 EGP Major facilitator Superfamily
AFHCFNDA_02793 1.4e-78 yvbK 3.1.3.25 K acetyltransferase
AFHCFNDA_02794 0.0 tcaA S response to antibiotic
AFHCFNDA_02795 4.2e-108 exoY M Membrane
AFHCFNDA_02796 9.8e-104 yvbG U UPF0056 membrane protein
AFHCFNDA_02797 2.5e-95 yvbF K Belongs to the GbsR family
AFHCFNDA_02798 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
AFHCFNDA_02799 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
AFHCFNDA_02800 9.7e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFHCFNDA_02801 5.4e-108 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
AFHCFNDA_02802 4.3e-76 yvbF K Belongs to the GbsR family
AFHCFNDA_02803 2.6e-203 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
AFHCFNDA_02804 4.7e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
AFHCFNDA_02805 8.2e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
AFHCFNDA_02806 4.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
AFHCFNDA_02807 1.6e-123 mutF V ABC transporter, ATP-binding protein
AFHCFNDA_02808 1e-120 spaE S ABC-2 family transporter protein
AFHCFNDA_02809 6.8e-131 mutG S ABC-2 family transporter protein
AFHCFNDA_02810 1.3e-119 K Transcriptional regulatory protein, C terminal
AFHCFNDA_02811 6.5e-241 T His Kinase A (phosphoacceptor) domain
AFHCFNDA_02812 1.4e-50 yodB K transcriptional
AFHCFNDA_02813 9.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
AFHCFNDA_02814 1.6e-67 K transcriptional
AFHCFNDA_02815 6e-35 yvzC K Transcriptional
AFHCFNDA_02816 4.2e-20 secG U Preprotein translocase subunit SecG
AFHCFNDA_02817 1.6e-142 est 3.1.1.1 S Carboxylesterase
AFHCFNDA_02818 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
AFHCFNDA_02819 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AFHCFNDA_02821 1.8e-42 yrdF K ribonuclease inhibitor
AFHCFNDA_02822 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFHCFNDA_02823 2.2e-157 ytlI K LysR substrate binding domain
AFHCFNDA_02824 2.5e-100 ytmI K Acetyltransferase (GNAT) domain
AFHCFNDA_02825 1.7e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
AFHCFNDA_02826 2.4e-131 tcyK M Bacterial periplasmic substrate-binding proteins
AFHCFNDA_02827 2.1e-118 tcyL P Binding-protein-dependent transport system inner membrane component
AFHCFNDA_02828 5.1e-117 tcyM U Binding-protein-dependent transport system inner membrane component
AFHCFNDA_02829 1.5e-138 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
AFHCFNDA_02830 9.1e-176 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFHCFNDA_02831 1e-44 ytnI O COG0695 Glutaredoxin and related proteins
AFHCFNDA_02832 5.6e-250 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFHCFNDA_02833 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AFHCFNDA_02834 8.9e-187 yvaA 1.1.1.371 S Oxidoreductase
AFHCFNDA_02835 1.4e-47 csoR S transcriptional
AFHCFNDA_02836 9.9e-29 copZ P Heavy-metal-associated domain
AFHCFNDA_02837 0.0 copA 3.6.3.54 P P-type ATPase
AFHCFNDA_02838 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
AFHCFNDA_02839 7.7e-99 bdbD O Thioredoxin
AFHCFNDA_02840 8.6e-72 bdbC O Required for disulfide bond formation in some proteins
AFHCFNDA_02841 9.1e-139 S Metallo-peptidase family M12
AFHCFNDA_02842 1e-97 yvgT S membrane
AFHCFNDA_02843 4.7e-81 helD 3.6.4.12 L DNA helicase
AFHCFNDA_02844 8.7e-291 helD 3.6.4.12 L DNA helicase
AFHCFNDA_02845 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AFHCFNDA_02846 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
AFHCFNDA_02847 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
AFHCFNDA_02848 2.3e-84 yvgO
AFHCFNDA_02849 5e-156 yvgN S reductase
AFHCFNDA_02850 7.3e-174 yfiN V COG0842 ABC-type multidrug transport system, permease component
AFHCFNDA_02851 3e-185 yfiM V ABC-2 type transporter
AFHCFNDA_02852 6.8e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
AFHCFNDA_02853 5.6e-171 T Histidine kinase
AFHCFNDA_02854 3.3e-113 yfiK K Regulator
AFHCFNDA_02855 1.2e-99 modB P COG4149 ABC-type molybdate transport system, permease component
AFHCFNDA_02856 4.2e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
AFHCFNDA_02857 5.4e-159 yvgK P COG1910 Periplasmic molybdate-binding protein domain
AFHCFNDA_02858 3.5e-163 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AFHCFNDA_02859 3e-166 ltaS 2.7.8.20 M Belongs to the LTA synthase family
AFHCFNDA_02860 3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
AFHCFNDA_02861 5.2e-13 S Small spore protein J (Spore_SspJ)
AFHCFNDA_02862 3e-233 yvsH E Arginine ornithine antiporter
AFHCFNDA_02863 4e-122 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AFHCFNDA_02864 5.8e-177 fhuD P ABC transporter
AFHCFNDA_02865 1.5e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_02866 1.2e-167 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_02867 4.5e-146 fhuC 3.6.3.34 HP ABC transporter
AFHCFNDA_02868 9.9e-60 yvrL S Regulatory protein YrvL
AFHCFNDA_02869 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
AFHCFNDA_02870 1.6e-15 S YvrJ protein family
AFHCFNDA_02871 2.1e-100 yvrI K RNA polymerase
AFHCFNDA_02872 6.2e-35
AFHCFNDA_02873 5.7e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_02874 0.0 T PhoQ Sensor
AFHCFNDA_02875 4.3e-166 yvrE G SMP-30/Gluconolaconase/LRE-like region
AFHCFNDA_02876 1e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFHCFNDA_02877 1.1e-164 yvrC P ABC transporter substrate-binding protein
AFHCFNDA_02878 2.5e-176 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFHCFNDA_02879 3.1e-202 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
AFHCFNDA_02880 2.3e-96 yvqK 2.5.1.17 S Adenosyltransferase
AFHCFNDA_02881 1.2e-220 yvqJ EGP Major facilitator Superfamily
AFHCFNDA_02882 6.9e-44 liaI S membrane
AFHCFNDA_02883 8.7e-90 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
AFHCFNDA_02884 2.1e-117 liaG S Putative adhesin
AFHCFNDA_02885 4.4e-124 yvqF S Cell wall-active antibiotics response 4TMS YvqF
AFHCFNDA_02886 1.1e-192 vraS 2.7.13.3 T Histidine kinase
AFHCFNDA_02887 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFHCFNDA_02888 7.6e-192 gerAC S Spore germination B3/ GerAC like, C-terminal
AFHCFNDA_02889 4.6e-181 gerAB E Spore germination protein
AFHCFNDA_02890 1.1e-254 gerAA EG Spore germination protein
AFHCFNDA_02891 6.6e-24 S Protein of unknown function (DUF3970)
AFHCFNDA_02892 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
AFHCFNDA_02893 3e-154 yuxN K Transcriptional regulator
AFHCFNDA_02894 1.3e-23
AFHCFNDA_02895 6.3e-249 cssS 2.7.13.3 T PhoQ Sensor
AFHCFNDA_02896 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_02897 3.5e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AFHCFNDA_02898 1.5e-77 dps P Belongs to the Dps family
AFHCFNDA_02899 3.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
AFHCFNDA_02900 0.0 pepF2 E COG1164 Oligoendopeptidase F
AFHCFNDA_02901 1e-46 S YusW-like protein
AFHCFNDA_02902 3.1e-150 yusV 3.6.3.34 HP ABC transporter
AFHCFNDA_02903 8.1e-38 yusU S Protein of unknown function (DUF2573)
AFHCFNDA_02904 2.2e-126 2.1.1.72 L DNA methylase
AFHCFNDA_02905 1.8e-16 K Helix-turn-helix XRE-family like proteins
AFHCFNDA_02906 9.8e-59 L PFAM Restriction endonuclease BamHI
AFHCFNDA_02907 1.5e-15
AFHCFNDA_02908 4.8e-08
AFHCFNDA_02909 1.2e-08 lexA 3.4.21.88 KT domain protein
AFHCFNDA_02910 6.8e-159 L Recombinase
AFHCFNDA_02911 2.3e-22 S YopX protein
AFHCFNDA_02913 2.4e-120 xkdC L IstB-like ATP binding protein
AFHCFNDA_02914 1.4e-29 3.1.3.16 L DnaD domain protein
AFHCFNDA_02915 6.4e-127 recT L RecT family
AFHCFNDA_02916 5.9e-153 yqaJ L YqaJ-like viral recombinase domain
AFHCFNDA_02918 1.2e-07 S Hypothetical protein Yqai
AFHCFNDA_02920 4.2e-85
AFHCFNDA_02921 9.6e-61 S DNA binding
AFHCFNDA_02922 3.8e-32
AFHCFNDA_02923 1.5e-12 K Helix-turn-helix XRE-family like proteins
AFHCFNDA_02924 7.9e-16 K Helix-turn-helix XRE-family like proteins
AFHCFNDA_02925 1.3e-48
AFHCFNDA_02926 1.7e-25 S Protein of unknown function (DUF4064)
AFHCFNDA_02927 2.4e-30 yqaB E IrrE N-terminal-like domain
AFHCFNDA_02928 2.3e-77 S Phage integrase family
AFHCFNDA_02929 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
AFHCFNDA_02930 6.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AFHCFNDA_02931 5.3e-125 ydiL S CAAX protease self-immunity
AFHCFNDA_02932 1.7e-27 ydiK S Domain of unknown function (DUF4305)
AFHCFNDA_02933 1.2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFHCFNDA_02934 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
AFHCFNDA_02935 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AFHCFNDA_02936 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
AFHCFNDA_02937 4e-310 ydiF S ABC transporter
AFHCFNDA_02938 8.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AFHCFNDA_02939 9e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
AFHCFNDA_02940 5.1e-122 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
AFHCFNDA_02941 3.2e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
AFHCFNDA_02942 4.1e-173 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AFHCFNDA_02943 1.4e-56 ydcK S Belongs to the SprT family
AFHCFNDA_02944 1.7e-14
AFHCFNDA_02945 0.0 yhgF K COG2183 Transcriptional accessory protein
AFHCFNDA_02946 2.5e-104 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
AFHCFNDA_02947 2e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFHCFNDA_02948 6.6e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
AFHCFNDA_02949 2.7e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
AFHCFNDA_02950 1.8e-184 rsbU 3.1.3.3 KT phosphatase
AFHCFNDA_02951 4.2e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
AFHCFNDA_02952 1.8e-57 rsbS T antagonist
AFHCFNDA_02953 3e-137 rsbR T Positive regulator of sigma-B
AFHCFNDA_02954 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
AFHCFNDA_02955 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
AFHCFNDA_02956 3.9e-215 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFHCFNDA_02957 1.3e-179 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
AFHCFNDA_02958 5.4e-54 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
AFHCFNDA_02959 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
AFHCFNDA_02960 6.6e-252 ydbT S Membrane
AFHCFNDA_02961 4.6e-61 ydbS S Bacterial PH domain
AFHCFNDA_02962 1.8e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
AFHCFNDA_02963 3.7e-249 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
AFHCFNDA_02964 1.3e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
AFHCFNDA_02965 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
AFHCFNDA_02966 4.4e-118 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFHCFNDA_02967 9.2e-10 S Fur-regulated basic protein A
AFHCFNDA_02968 3.5e-12 S Fur-regulated basic protein B
AFHCFNDA_02969 2.7e-200 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
AFHCFNDA_02970 4.6e-52 ydbL
AFHCFNDA_02971 4.8e-36 bofA S Sigma-K factor-processing regulatory protein BofA
AFHCFNDA_02972 3.6e-32 yaaL S Protein of unknown function (DUF2508)
AFHCFNDA_02973 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AFHCFNDA_02974 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AFHCFNDA_02975 2.3e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AFHCFNDA_02976 9.5e-83 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
AFHCFNDA_02977 6.6e-96 yaaI Q COG1335 Amidases related to nicotinamidase
AFHCFNDA_02978 3.9e-208 yaaH M Glycoside Hydrolase Family
AFHCFNDA_02979 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
AFHCFNDA_02980 6.6e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
AFHCFNDA_02981 1.3e-09
AFHCFNDA_02982 2.3e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
AFHCFNDA_02983 2.1e-201 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AFHCFNDA_02984 4.7e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AFHCFNDA_02985 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AFHCFNDA_02986 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
AFHCFNDA_02987 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
AFHCFNDA_02988 1.5e-175 yaaC S YaaC-like Protein
AFHCFNDA_02989 0.0 L Transposase and inactivated derivatives, TnpA family
AFHCFNDA_02990 7.1e-85 L resolvase
AFHCFNDA_02991 1.3e-78
AFHCFNDA_02993 6e-26 S Protein of unknown function (DUF1657)
AFHCFNDA_02994 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFHCFNDA_02995 2.6e-80 spoVAC S stage V sporulation protein AC
AFHCFNDA_02996 1e-195 spoVAD I Stage V sporulation protein AD
AFHCFNDA_02997 8.5e-57 spoVAE S stage V sporulation protein
AFHCFNDA_02998 5.8e-29 S Protein of unknown function (DUF1657)
AFHCFNDA_02999 2.1e-149 yetF1 S membrane
AFHCFNDA_03000 1.2e-70 S Protein of unknown function (DUF421)
AFHCFNDA_03001 2.7e-285 clsA_1 I PLD-like domain
AFHCFNDA_03002 2.5e-92 S Protein of unknown function (DUF421)
AFHCFNDA_03003 9.3e-142 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
AFHCFNDA_03004 1.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
AFHCFNDA_03005 4.3e-92 yuaB
AFHCFNDA_03006 3.4e-92 yuaC K Belongs to the GbsR family
AFHCFNDA_03007 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
AFHCFNDA_03008 6.7e-226 gbsB 1.1.1.1 C alcohol dehydrogenase
AFHCFNDA_03009 1.2e-103 yuaD S MOSC domain
AFHCFNDA_03010 2.2e-79 yuaE S DinB superfamily
AFHCFNDA_03011 4.9e-80 yuaF OU Membrane protein implicated in regulation of membrane protease activity
AFHCFNDA_03012 6.1e-176 yuaG 3.4.21.72 S protein conserved in bacteria
AFHCFNDA_03013 2.7e-92 thiT S Thiamine transporter protein (Thia_YuaJ)
AFHCFNDA_03014 1.1e-75 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_03015 2.2e-67 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_03016 9e-245 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
AFHCFNDA_03018 2.1e-110 S YqaJ-like viral recombinase domain
AFHCFNDA_03019 1.3e-109 recT L Recombinational DNA repair protein (RecE pathway)
AFHCFNDA_03020 3e-43 3.1.3.16 L DnaD domain protein
AFHCFNDA_03021 2e-55 L Bacterial dnaA protein
AFHCFNDA_03024 2.6e-53 S Protein of unknown function (DUF1064)
AFHCFNDA_03026 1.6e-62 pbuX F xanthine
AFHCFNDA_03027 2.9e-94 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
AFHCFNDA_03028 5.4e-127 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AFHCFNDA_03029 3.9e-148 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AFHCFNDA_03030 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
AFHCFNDA_03032 6.6e-22 S YpzG-like protein
AFHCFNDA_03033 2e-74 yqgA
AFHCFNDA_03034 1.3e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
AFHCFNDA_03035 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
AFHCFNDA_03036 5.9e-97 ypsA S Belongs to the UPF0398 family
AFHCFNDA_03037 5.6e-23 cotD S Inner spore coat protein D
AFHCFNDA_03039 7.5e-225 yprB L RNase_H superfamily
AFHCFNDA_03040 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
AFHCFNDA_03041 1.3e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
AFHCFNDA_03042 4.4e-60 hspX O Belongs to the small heat shock protein (HSP20) family
AFHCFNDA_03043 1.5e-38 yppG S YppG-like protein
AFHCFNDA_03045 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
AFHCFNDA_03048 9.2e-178 yppC S Protein of unknown function (DUF2515)
AFHCFNDA_03049 1.2e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AFHCFNDA_03050 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFHCFNDA_03051 1.4e-86 ypoC
AFHCFNDA_03052 7.8e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFHCFNDA_03053 3.4e-129 dnaD L DNA replication protein DnaD
AFHCFNDA_03054 7.1e-250 asnS 6.1.1.22 J asparaginyl-tRNA
AFHCFNDA_03055 5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
AFHCFNDA_03056 1.4e-73 ypmB S protein conserved in bacteria
AFHCFNDA_03057 6.7e-23 ypmA S Protein of unknown function (DUF4264)
AFHCFNDA_03058 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
AFHCFNDA_03059 3.9e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AFHCFNDA_03060 1.2e-152 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AFHCFNDA_03061 2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
AFHCFNDA_03062 4.9e-179 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
AFHCFNDA_03063 9.5e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AFHCFNDA_03064 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
AFHCFNDA_03065 1e-125 bshB1 S proteins, LmbE homologs
AFHCFNDA_03066 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
AFHCFNDA_03067 3.8e-145 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
AFHCFNDA_03068 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
AFHCFNDA_03069 4.7e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
AFHCFNDA_03070 2.5e-222 oxdC 4.1.1.2 G Oxalate decarboxylase
AFHCFNDA_03071 1.5e-138 ypjB S sporulation protein
AFHCFNDA_03072 5.2e-99 ypjA S membrane
AFHCFNDA_03073 5.7e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
AFHCFNDA_03074 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
AFHCFNDA_03075 2.5e-94 qcrA C Menaquinol-cytochrome c reductase
AFHCFNDA_03076 8.3e-73 ypiF S Protein of unknown function (DUF2487)
AFHCFNDA_03077 8.1e-99 ypiB S Belongs to the UPF0302 family
AFHCFNDA_03078 1.5e-228 S COG0457 FOG TPR repeat
AFHCFNDA_03079 1.3e-227 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
AFHCFNDA_03080 1.8e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
AFHCFNDA_03081 3.1e-198 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AFHCFNDA_03082 5.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
AFHCFNDA_03083 5.6e-225 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AFHCFNDA_03084 3.3e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
AFHCFNDA_03085 3e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
AFHCFNDA_03086 6.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AFHCFNDA_03087 5.8e-283 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFHCFNDA_03088 1.7e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
AFHCFNDA_03089 6.3e-199 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AFHCFNDA_03090 2.3e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AFHCFNDA_03091 7.4e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
AFHCFNDA_03092 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
AFHCFNDA_03093 4.8e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFHCFNDA_03094 1.5e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
AFHCFNDA_03095 1.5e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
AFHCFNDA_03096 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
AFHCFNDA_03097 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
AFHCFNDA_03098 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFHCFNDA_03099 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
AFHCFNDA_03100 1.3e-10 yphF
AFHCFNDA_03101 7.1e-130 yphF
AFHCFNDA_03102 1.5e-16 yphE S Protein of unknown function (DUF2768)
AFHCFNDA_03103 5.2e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
AFHCFNDA_03104 1.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
AFHCFNDA_03105 2.4e-99 yphA
AFHCFNDA_03106 4.7e-08 S YpzI-like protein
AFHCFNDA_03107 1.5e-178 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
AFHCFNDA_03108 2.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
AFHCFNDA_03109 7.5e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
AFHCFNDA_03110 2.5e-12 S Family of unknown function (DUF5359)
AFHCFNDA_03111 1.1e-57 ypfA M Flagellar protein YcgR
AFHCFNDA_03112 2.5e-245 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
AFHCFNDA_03113 4.7e-149 sleB 3.5.1.28 M Spore cortex-lytic enzyme
AFHCFNDA_03114 1.6e-120 prsW S Involved in the degradation of specific anti-sigma factors
AFHCFNDA_03115 7.2e-186 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
AFHCFNDA_03116 2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
AFHCFNDA_03117 2.2e-105 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
AFHCFNDA_03118 1.9e-141 ypbG S Calcineurin-like phosphoesterase superfamily domain
AFHCFNDA_03119 1.1e-83 ypbF S Protein of unknown function (DUF2663)
AFHCFNDA_03120 3.7e-60 ypbE M Lysin motif
AFHCFNDA_03121 2.4e-96 ypbD S metal-dependent membrane protease
AFHCFNDA_03122 2.5e-275 recQ 3.6.4.12 L DNA helicase
AFHCFNDA_03123 1.5e-189 ypbB 5.1.3.1 S protein conserved in bacteria
AFHCFNDA_03124 3.6e-41 fer C Ferredoxin
AFHCFNDA_03125 1.6e-92 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
AFHCFNDA_03126 2.2e-290 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFHCFNDA_03127 3.1e-169 rsiX
AFHCFNDA_03128 2.2e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
AFHCFNDA_03129 0.0 resE 2.7.13.3 T Histidine kinase
AFHCFNDA_03130 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_03131 1.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
AFHCFNDA_03132 1.1e-308 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
AFHCFNDA_03133 3.4e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
AFHCFNDA_03134 6.4e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
AFHCFNDA_03135 3.8e-88 spmB S Spore maturation protein
AFHCFNDA_03136 1.3e-102 spmA S Spore maturation protein
AFHCFNDA_03137 1.1e-209 dacB 3.4.16.4 M Belongs to the peptidase S11 family
AFHCFNDA_03138 8.1e-82 ypuI S Protein of unknown function (DUF3907)
AFHCFNDA_03139 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFHCFNDA_03140 3.1e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AFHCFNDA_03142 6.2e-88 ypuF S Domain of unknown function (DUF309)
AFHCFNDA_03143 1e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFHCFNDA_03144 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
AFHCFNDA_03145 2.3e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AFHCFNDA_03146 7.2e-110 ribE 2.5.1.9 H Riboflavin synthase
AFHCFNDA_03147 6.2e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AFHCFNDA_03148 5.1e-46 ypuD
AFHCFNDA_03149 3.9e-96 sipT 3.4.21.89 U Belongs to the peptidase S26 family
AFHCFNDA_03150 8.5e-79 ccdC1 O Protein of unknown function (DUF1453)
AFHCFNDA_03151 5.7e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AFHCFNDA_03152 2.6e-150 ypuA S Secreted protein
AFHCFNDA_03153 6.5e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
AFHCFNDA_03154 6.2e-266 spoVAF EG Stage V sporulation protein AF
AFHCFNDA_03155 2.4e-107 spoVAEA S stage V sporulation protein
AFHCFNDA_03156 2.5e-56 spoVAEB S stage V sporulation protein
AFHCFNDA_03157 3.5e-188 spoVAD I Stage V sporulation protein AD
AFHCFNDA_03158 1.3e-78 spoVAC S stage V sporulation protein AC
AFHCFNDA_03159 4.5e-68 spoVAB S Stage V sporulation protein AB
AFHCFNDA_03160 1.5e-109 spoVAA S Stage V sporulation protein AA
AFHCFNDA_03161 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AFHCFNDA_03162 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
AFHCFNDA_03163 2.3e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
AFHCFNDA_03164 5.9e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
AFHCFNDA_03165 4.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AFHCFNDA_03166 3.5e-227 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
AFHCFNDA_03167 2.7e-163 xerD L recombinase XerD
AFHCFNDA_03168 6.4e-37 S Protein of unknown function (DUF4227)
AFHCFNDA_03169 2.7e-79 fur P Belongs to the Fur family
AFHCFNDA_03170 2.7e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
AFHCFNDA_03171 8.1e-32 yqkK
AFHCFNDA_03172 3e-23
AFHCFNDA_03173 3.6e-241 mleA 1.1.1.38 C malic enzyme
AFHCFNDA_03174 3.2e-240 mleN C Na H antiporter
AFHCFNDA_03175 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
AFHCFNDA_03176 1.2e-183 ansA 3.5.1.1 EJ L-asparaginase
AFHCFNDA_03177 5e-57 ansR K Transcriptional regulator
AFHCFNDA_03178 2.5e-214 yqxK 3.6.4.12 L DNA helicase
AFHCFNDA_03179 9e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
AFHCFNDA_03181 1.2e-163 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
AFHCFNDA_03183 3.4e-166 yqkD S COG1073 Hydrolases of the alpha beta superfamily
AFHCFNDA_03184 3.2e-39 yqkC S Protein of unknown function (DUF2552)
AFHCFNDA_03185 1.6e-58 yqkB S Belongs to the HesB IscA family
AFHCFNDA_03186 9e-165 yqkA K GrpB protein
AFHCFNDA_03188 2.8e-87 yqjY K acetyltransferase
AFHCFNDA_03189 5.7e-233 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFHCFNDA_03190 9.3e-56 S YolD-like protein
AFHCFNDA_03192 1.8e-145 yueF S transporter activity
AFHCFNDA_03194 5e-176 coaA 2.7.1.33 F Pantothenic acid kinase
AFHCFNDA_03195 1.1e-242 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
AFHCFNDA_03196 1.8e-136 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
AFHCFNDA_03197 2.3e-168 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
AFHCFNDA_03198 7.9e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFHCFNDA_03199 1.8e-156 K LysR substrate binding domain
AFHCFNDA_03200 1.6e-46 S GlpM protein
AFHCFNDA_03201 8.2e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
AFHCFNDA_03202 4.5e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
AFHCFNDA_03203 4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AFHCFNDA_03204 2.8e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
AFHCFNDA_03205 7.7e-285 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AFHCFNDA_03206 1.3e-265 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AFHCFNDA_03207 9.4e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFHCFNDA_03208 7.4e-27 yqzJ
AFHCFNDA_03209 2.1e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AFHCFNDA_03210 1.2e-200 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
AFHCFNDA_03211 3e-284 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
AFHCFNDA_03212 2e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
AFHCFNDA_03214 3.6e-91 yqjB S protein conserved in bacteria
AFHCFNDA_03215 7.7e-169 yqjA S Putative aromatic acid exporter C-terminal domain
AFHCFNDA_03216 1.5e-124 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
AFHCFNDA_03217 1.1e-105 artQ E COG0765 ABC-type amino acid transport system, permease component
AFHCFNDA_03218 9.4e-133 artP ET Belongs to the bacterial solute-binding protein 3 family
AFHCFNDA_03219 1e-75 yqiW S Belongs to the UPF0403 family
AFHCFNDA_03220 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
AFHCFNDA_03221 3.5e-193 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
AFHCFNDA_03222 6.7e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
AFHCFNDA_03223 7.8e-164 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
AFHCFNDA_03224 5.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
AFHCFNDA_03225 2e-205 buk 2.7.2.7 C Belongs to the acetokinase family
AFHCFNDA_03226 2.6e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
AFHCFNDA_03227 1.3e-149 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
AFHCFNDA_03228 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
AFHCFNDA_03229 2.7e-33 yqzF S Protein of unknown function (DUF2627)
AFHCFNDA_03230 7.1e-156 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AFHCFNDA_03231 7.8e-266 prpD 4.2.1.79 S 2-methylcitrate dehydratase
AFHCFNDA_03232 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
AFHCFNDA_03233 2.5e-86 mmgC I acyl-CoA dehydrogenase
AFHCFNDA_03234 1.9e-99 mmgC I acyl-CoA dehydrogenase
AFHCFNDA_03235 1.3e-143 hbdA 1.1.1.157 I Dehydrogenase
AFHCFNDA_03236 2.7e-208 mmgA 2.3.1.9 I Belongs to the thiolase family
AFHCFNDA_03237 9.6e-127 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AFHCFNDA_03238 1.4e-97 amiC 3.5.1.28 M Cell wall hydrolase autolysin
AFHCFNDA_03239 5.7e-17
AFHCFNDA_03240 2.3e-92 ytaF P Probably functions as a manganese efflux pump
AFHCFNDA_03241 3.7e-111 K Protein of unknown function (DUF1232)
AFHCFNDA_03243 5.8e-208 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
AFHCFNDA_03246 2.9e-202 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AFHCFNDA_03248 2.7e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
AFHCFNDA_03249 3.2e-234 rseP 3.4.21.116 M Stage IV sporulation protein B
AFHCFNDA_03250 6.2e-310 recN L May be involved in recombinational repair of damaged DNA
AFHCFNDA_03251 4.3e-77 argR K Regulates arginine biosynthesis genes
AFHCFNDA_03252 9.9e-152 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
AFHCFNDA_03253 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AFHCFNDA_03254 7e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
AFHCFNDA_03255 1.3e-38 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFHCFNDA_03256 2.5e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
AFHCFNDA_03257 5.7e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AFHCFNDA_03258 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AFHCFNDA_03259 1.4e-66 yqhY S protein conserved in bacteria
AFHCFNDA_03260 8.4e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
AFHCFNDA_03261 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
AFHCFNDA_03262 1.3e-58 spoIIIAH S SpoIIIAH-like protein
AFHCFNDA_03263 1.4e-114 spoIIIAG S stage III sporulation protein AG
AFHCFNDA_03264 2.9e-100 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
AFHCFNDA_03265 4.1e-199 spoIIIAE S stage III sporulation protein AE
AFHCFNDA_03266 3.3e-41 spoIIIAD S Stage III sporulation protein AD
AFHCFNDA_03267 7.6e-29 spoIIIAC S stage III sporulation protein AC
AFHCFNDA_03268 1e-82 spoIIIAB S Stage III sporulation protein
AFHCFNDA_03269 1.7e-165 spoIIIAA S stage III sporulation protein AA
AFHCFNDA_03270 6.7e-36 yqhV S Protein of unknown function (DUF2619)
AFHCFNDA_03271 2.1e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AFHCFNDA_03272 1.2e-162 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
AFHCFNDA_03273 1.1e-84 yqhR S Conserved membrane protein YqhR
AFHCFNDA_03274 9.1e-170 yqhQ S Protein of unknown function (DUF1385)
AFHCFNDA_03275 1.2e-59 yqhP
AFHCFNDA_03276 5.1e-159 yqhO S esterase of the alpha-beta hydrolase superfamily
AFHCFNDA_03277 4.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
AFHCFNDA_03278 4.1e-158 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
AFHCFNDA_03279 1.8e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
AFHCFNDA_03280 3.6e-282 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFHCFNDA_03281 1.2e-247 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AFHCFNDA_03282 5.7e-200 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
AFHCFNDA_03283 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
AFHCFNDA_03284 3e-150 yqhG S Bacterial protein YqhG of unknown function
AFHCFNDA_03285 1.7e-21 sinI S Anti-repressor SinI
AFHCFNDA_03286 3.9e-54 sinR K transcriptional
AFHCFNDA_03287 1.5e-138 tasA S Cell division protein FtsN
AFHCFNDA_03288 5.2e-67 sipW 3.4.21.89 U Signal peptidase
AFHCFNDA_03289 3.6e-112 yqxM
AFHCFNDA_03290 1.1e-53 yqzG S Protein of unknown function (DUF3889)
AFHCFNDA_03291 1.5e-25 yqzE S YqzE-like protein
AFHCFNDA_03292 5.4e-57 S ComG operon protein 7
AFHCFNDA_03293 4.1e-21 comGF U Putative Competence protein ComGF
AFHCFNDA_03294 1.2e-20 comGE
AFHCFNDA_03295 6.4e-70 gspH NU Tfp pilus assembly protein FimT
AFHCFNDA_03296 1.3e-48 comGC U Required for transformation and DNA binding
AFHCFNDA_03297 4e-179 comGB NU COG1459 Type II secretory pathway, component PulF
AFHCFNDA_03298 8.9e-198 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AFHCFNDA_03299 6.7e-181 corA P Mg2 transporter protein
AFHCFNDA_03300 1.5e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
AFHCFNDA_03301 3e-137 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFHCFNDA_03303 1.9e-62 yqgZ 1.20.4.1 P Belongs to the ArsC family
AFHCFNDA_03304 3.4e-36 yqgY S Protein of unknown function (DUF2626)
AFHCFNDA_03305 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
AFHCFNDA_03306 5.4e-20 yqgW S Protein of unknown function (DUF2759)
AFHCFNDA_03307 1.7e-48 yqgV S Thiamine-binding protein
AFHCFNDA_03308 2.3e-187 yqgU
AFHCFNDA_03309 5.3e-201 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
AFHCFNDA_03310 1.8e-178 glcK 2.7.1.2 G Glucokinase
AFHCFNDA_03311 1.6e-27 yqgQ S Protein conserved in bacteria
AFHCFNDA_03312 4.8e-203 nhaC C Na H antiporter
AFHCFNDA_03313 4e-07 yqgO
AFHCFNDA_03314 6e-89 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AFHCFNDA_03315 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
AFHCFNDA_03316 1.2e-50 yqzD
AFHCFNDA_03317 1.3e-73 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AFHCFNDA_03318 6.4e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFHCFNDA_03319 2.2e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
AFHCFNDA_03320 8.5e-154 pstA P Phosphate transport system permease
AFHCFNDA_03321 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
AFHCFNDA_03322 2.3e-154 pstS P Phosphate
AFHCFNDA_03323 0.0 pbpA 3.4.16.4 M penicillin-binding protein
AFHCFNDA_03324 3.3e-223 yqgE EGP Major facilitator superfamily
AFHCFNDA_03325 5.3e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
AFHCFNDA_03326 4.2e-70 yqgC S protein conserved in bacteria
AFHCFNDA_03327 2.4e-128 yqgB S Protein of unknown function (DUF1189)
AFHCFNDA_03328 4.2e-44 yqfZ M LysM domain
AFHCFNDA_03329 5e-199 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AFHCFNDA_03330 6.7e-52 yqfX S membrane
AFHCFNDA_03331 6.7e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
AFHCFNDA_03332 2.4e-71 zur P Belongs to the Fur family
AFHCFNDA_03333 1.1e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
AFHCFNDA_03334 9.3e-37 yqfT S Protein of unknown function (DUF2624)
AFHCFNDA_03335 2.9e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AFHCFNDA_03336 5.7e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
AFHCFNDA_03337 1.6e-25 yqfQ S YqfQ-like protein
AFHCFNDA_03338 1.9e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AFHCFNDA_03339 1.8e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AFHCFNDA_03340 1.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
AFHCFNDA_03341 1.3e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
AFHCFNDA_03342 3.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
AFHCFNDA_03343 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
AFHCFNDA_03344 8.7e-87 yaiI S Belongs to the UPF0178 family
AFHCFNDA_03345 1.4e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
AFHCFNDA_03346 1.3e-111 ccpN K CBS domain
AFHCFNDA_03347 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
AFHCFNDA_03348 3.7e-173 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
AFHCFNDA_03349 6.1e-140 recO L Involved in DNA repair and RecF pathway recombination
AFHCFNDA_03350 1.8e-16 S YqzL-like protein
AFHCFNDA_03351 5.2e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AFHCFNDA_03352 2.7e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
AFHCFNDA_03353 8.6e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
AFHCFNDA_03354 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AFHCFNDA_03355 0.0 yqfF S membrane-associated HD superfamily hydrolase
AFHCFNDA_03356 2.1e-174 phoH T Phosphate starvation-inducible protein PhoH
AFHCFNDA_03357 1.1e-207 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
AFHCFNDA_03358 9.3e-46 yqfC S sporulation protein YqfC
AFHCFNDA_03359 4.5e-23 yqfB
AFHCFNDA_03360 5.3e-120 yqfA S UPF0365 protein
AFHCFNDA_03361 6.1e-225 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
AFHCFNDA_03362 1.2e-68 yqeY S Yqey-like protein
AFHCFNDA_03363 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
AFHCFNDA_03364 1.7e-152 yqeW P COG1283 Na phosphate symporter
AFHCFNDA_03365 1.5e-258 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
AFHCFNDA_03366 2.8e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
AFHCFNDA_03367 6.6e-173 prmA J Methylates ribosomal protein L11
AFHCFNDA_03368 2.7e-197 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
AFHCFNDA_03369 0.0 dnaK O Heat shock 70 kDa protein
AFHCFNDA_03370 8.9e-72 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AFHCFNDA_03371 5.2e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
AFHCFNDA_03372 2.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
AFHCFNDA_03373 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
AFHCFNDA_03374 3.8e-54 yqxA S Protein of unknown function (DUF3679)
AFHCFNDA_03375 2.4e-220 spoIIP M stage II sporulation protein P
AFHCFNDA_03376 2.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AFHCFNDA_03377 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
AFHCFNDA_03378 2.7e-180 holA 2.7.7.7 L DNA polymerase III delta subunit
AFHCFNDA_03379 0.0 comEC S Competence protein ComEC
AFHCFNDA_03380 8e-105 comEB 3.5.4.12 F ComE operon protein 2
AFHCFNDA_03381 7.3e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
AFHCFNDA_03382 4.2e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AFHCFNDA_03383 3.2e-138 yqeM Q Methyltransferase
AFHCFNDA_03384 7.6e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
AFHCFNDA_03385 1.8e-101 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
AFHCFNDA_03386 9.5e-106 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AFHCFNDA_03387 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
AFHCFNDA_03388 1.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFHCFNDA_03389 3.8e-212 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
AFHCFNDA_03390 2e-94 yqeG S hydrolase of the HAD superfamily
AFHCFNDA_03392 4.1e-138 yqeF E GDSL-like Lipase/Acylhydrolase
AFHCFNDA_03393 8.4e-139 3.5.1.104 G Polysaccharide deacetylase
AFHCFNDA_03394 3.6e-106 yqeD S SNARE associated Golgi protein
AFHCFNDA_03395 3.2e-10 2.3.1.57 K Acetyltransferase (GNAT) domain
AFHCFNDA_03397 1.4e-215 EGP Major facilitator Superfamily
AFHCFNDA_03398 9.4e-20 S HNH endonuclease
AFHCFNDA_03399 5e-17 yqaO S Phage-like element PBSX protein XtrA
AFHCFNDA_03402 2.9e-21
AFHCFNDA_03404 2.2e-52 S SMI1-KNR4 cell-wall
AFHCFNDA_03405 2.2e-167 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
AFHCFNDA_03406 4.5e-79 yokF 3.1.31.1 L RNA catabolic process
AFHCFNDA_03407 1.5e-49 L Recombinase
AFHCFNDA_03408 3.1e-95 yqaB E IrrE N-terminal-like domain
AFHCFNDA_03410 1.1e-11 S Protein of unknown function (DUF4064)
AFHCFNDA_03411 1.1e-56 K sequence-specific DNA binding
AFHCFNDA_03412 1.6e-35 K Helix-turn-helix XRE-family like proteins
AFHCFNDA_03414 4.4e-103
AFHCFNDA_03418 3.4e-164 yqaJ L YqaJ-like viral recombinase domain
AFHCFNDA_03420 2.7e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
AFHCFNDA_03421 5.3e-19 V VanZ like family
AFHCFNDA_03423 3.1e-48
AFHCFNDA_03429 5.1e-07 S YopX protein
AFHCFNDA_03430 1.7e-47 yqaB E IrrE N-terminal-like domain
AFHCFNDA_03431 4.1e-11
AFHCFNDA_03432 4.5e-25 K sequence-specific DNA binding
AFHCFNDA_03435 1e-24
AFHCFNDA_03437 8.5e-32 K Phage regulatory protein Rha (Phage_pRha)
AFHCFNDA_03438 1.7e-75
AFHCFNDA_03444 8.6e-230 M domain protein
AFHCFNDA_03446 2.7e-167 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
AFHCFNDA_03448 1.6e-46 S dUTPase
AFHCFNDA_03449 3.7e-25
AFHCFNDA_03450 3e-62 H Acetyltransferase (GNAT) domain
AFHCFNDA_03451 4.3e-22 yokK S SMI1 / KNR4 family
AFHCFNDA_03452 5.5e-103 1.1.1.169 H 2-dehydropantoate 2-reductase
AFHCFNDA_03453 7.1e-90 yokH G SMI1 / KNR4 family
AFHCFNDA_03454 4.5e-31
AFHCFNDA_03455 2.6e-74 yobL S Bacterial EndoU nuclease
AFHCFNDA_03456 5.3e-40
AFHCFNDA_03458 1.7e-213 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFHCFNDA_03459 1.8e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
AFHCFNDA_03460 1.2e-121 yjcH P COG2382 Enterochelin esterase and related enzymes
AFHCFNDA_03461 7.8e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
AFHCFNDA_03462 2e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFHCFNDA_03463 8.8e-34 K SpoVT / AbrB like domain
AFHCFNDA_03464 2.1e-129 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
AFHCFNDA_03465 1.7e-120 S ABC-2 type transporter
AFHCFNDA_03466 2.4e-125 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
AFHCFNDA_03467 6.2e-33
AFHCFNDA_03468 0.0 yjcD 3.6.4.12 L DNA helicase
AFHCFNDA_03469 8.4e-38 spoVIF S Stage VI sporulation protein F
AFHCFNDA_03473 2.8e-55 yjcA S Protein of unknown function (DUF1360)
AFHCFNDA_03474 6.3e-53 cotV S Spore Coat Protein X and V domain
AFHCFNDA_03475 1.4e-21 cotW
AFHCFNDA_03476 1.3e-69 cotX S Spore Coat Protein X and V domain
AFHCFNDA_03477 1.3e-92 cotY S Spore coat protein Z
AFHCFNDA_03478 1.8e-80 cotZ S Spore coat protein
AFHCFNDA_03479 5.4e-72 yjbX S Spore coat protein
AFHCFNDA_03480 6.8e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
AFHCFNDA_03481 2.6e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
AFHCFNDA_03482 4.3e-178 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
AFHCFNDA_03483 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
AFHCFNDA_03484 7.5e-29 thiS H Thiamine biosynthesis
AFHCFNDA_03485 1.8e-201 thiO 1.4.3.19 E Glycine oxidase
AFHCFNDA_03486 4e-102 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
AFHCFNDA_03487 8.7e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AFHCFNDA_03488 1.8e-307 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
AFHCFNDA_03489 1.9e-80 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
AFHCFNDA_03490 2.7e-48 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
AFHCFNDA_03491 4.1e-156 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFHCFNDA_03492 3.9e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFHCFNDA_03493 1.9e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
AFHCFNDA_03494 5e-60 yjbL S Belongs to the UPF0738 family
AFHCFNDA_03495 7.1e-93 yjbK S protein conserved in bacteria
AFHCFNDA_03496 7.9e-107 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
AFHCFNDA_03497 5.9e-70 yjbI S Bacterial-like globin
AFHCFNDA_03498 2.6e-166 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
AFHCFNDA_03499 5.8e-19
AFHCFNDA_03500 0.0 pepF E oligoendopeptidase F
AFHCFNDA_03501 1.9e-201 yjbF S Competence protein
AFHCFNDA_03502 5e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
AFHCFNDA_03503 1.1e-108 yjbE P Integral membrane protein TerC family
AFHCFNDA_03504 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
AFHCFNDA_03505 2.9e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
AFHCFNDA_03506 9.2e-220 S Putative glycosyl hydrolase domain
AFHCFNDA_03507 8.8e-170 oppF E Belongs to the ABC transporter superfamily
AFHCFNDA_03508 1.2e-199 oppD P Belongs to the ABC transporter superfamily
AFHCFNDA_03509 6.5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFHCFNDA_03510 7.8e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFHCFNDA_03511 0.0 oppA E ABC transporter substrate-binding protein
AFHCFNDA_03512 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
AFHCFNDA_03513 5.5e-146 yjbA S Belongs to the UPF0736 family
AFHCFNDA_03514 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFHCFNDA_03515 4.8e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFHCFNDA_03516 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
AFHCFNDA_03517 1.7e-182 appF E Belongs to the ABC transporter superfamily
AFHCFNDA_03518 1.9e-178 appD P Belongs to the ABC transporter superfamily
AFHCFNDA_03519 2.1e-140 yjaZ O Zn-dependent protease
AFHCFNDA_03520 1.2e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFHCFNDA_03521 1.6e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFHCFNDA_03523 3.3e-26 comZ S ComZ
AFHCFNDA_03524 2e-163 med S Transcriptional activator protein med
AFHCFNDA_03525 5.5e-98 yjaV
AFHCFNDA_03526 4.4e-132 yjaU I carboxylic ester hydrolase activity
AFHCFNDA_03527 6.3e-22 yjzD S Protein of unknown function (DUF2929)
AFHCFNDA_03528 2.1e-27 yjzC S YjzC-like protein
AFHCFNDA_03529 3.4e-172 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AFHCFNDA_03530 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
AFHCFNDA_03531 1.4e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
AFHCFNDA_03532 2.2e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
AFHCFNDA_03533 9.8e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
AFHCFNDA_03534 3.2e-220 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AFHCFNDA_03535 1.4e-192 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AFHCFNDA_03536 9.4e-87 norB G Major Facilitator Superfamily
AFHCFNDA_03537 5.1e-265 yitY C D-arabinono-1,4-lactone oxidase
AFHCFNDA_03538 3.6e-70 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
AFHCFNDA_03539 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
AFHCFNDA_03540 3.2e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
AFHCFNDA_03541 4.4e-149 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
AFHCFNDA_03542 2e-07
AFHCFNDA_03543 2.8e-25 S Protein of unknown function (DUF3813)
AFHCFNDA_03544 1.2e-79 ipi S Intracellular proteinase inhibitor
AFHCFNDA_03545 8.7e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
AFHCFNDA_03546 8.2e-154 yitS S protein conserved in bacteria
AFHCFNDA_03547 1.8e-229 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
AFHCFNDA_03548 1.9e-175 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
AFHCFNDA_03549 5e-147 yufN S ABC transporter substrate-binding protein PnrA-like
AFHCFNDA_03550 3.9e-156 cvfB S protein conserved in bacteria
AFHCFNDA_03551 1.9e-54 yajQ S Belongs to the UPF0234 family
AFHCFNDA_03552 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
AFHCFNDA_03553 6e-76 yjcF S Acetyltransferase (GNAT) domain
AFHCFNDA_03554 2.4e-49 mcbG S Pentapeptide repeats (9 copies)
AFHCFNDA_03555 1.5e-187 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
AFHCFNDA_03556 1e-73 argO S Lysine exporter protein LysE YggA
AFHCFNDA_03557 5.2e-77 yisT S DinB family
AFHCFNDA_03558 4.4e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
AFHCFNDA_03559 8.6e-142 purR K helix_turn _helix lactose operon repressor
AFHCFNDA_03560 8e-157 yisR K Transcriptional regulator
AFHCFNDA_03561 1e-241 yisQ V Mate efflux family protein
AFHCFNDA_03562 7e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
AFHCFNDA_03563 0.0 asnO 6.3.5.4 E Asparagine synthase
AFHCFNDA_03564 3.1e-90 yisN S Protein of unknown function (DUF2777)
AFHCFNDA_03565 0.0 wprA O Belongs to the peptidase S8 family
AFHCFNDA_03566 1.9e-59 yisL S UPF0344 protein
AFHCFNDA_03567 2e-166 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
AFHCFNDA_03568 1.6e-08 yisI S Spo0E like sporulation regulatory protein
AFHCFNDA_03569 8.4e-34 gerPA S Spore germination protein
AFHCFNDA_03570 4.8e-32 gerPB S cell differentiation
AFHCFNDA_03571 5e-60 gerPC S Spore germination protein
AFHCFNDA_03572 7.7e-22 gerPD S Spore germination protein
AFHCFNDA_03573 1e-58 gerPE S Spore germination protein GerPE
AFHCFNDA_03574 1.7e-31 gerPF S Spore germination protein gerPA/gerPF
AFHCFNDA_03575 3.9e-50 yisB V COG1403 Restriction endonuclease
AFHCFNDA_03576 0.0 sbcC L COG0419 ATPase involved in DNA repair
AFHCFNDA_03577 9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
AFHCFNDA_03578 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
AFHCFNDA_03579 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
AFHCFNDA_03580 1.2e-118 ydfS S Protein of unknown function (DUF421)
AFHCFNDA_03581 1.4e-82 yhjR S Rubrerythrin
AFHCFNDA_03582 3.5e-106 K QacR-like protein, C-terminal region
AFHCFNDA_03583 2.6e-198 blt EGP Major facilitator Superfamily
AFHCFNDA_03584 7.9e-184 abrB S membrane
AFHCFNDA_03585 6.1e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_03586 3.4e-264 yhjG CH FAD binding domain
AFHCFNDA_03587 6.6e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
AFHCFNDA_03588 1e-105 yhjE S SNARE associated Golgi protein
AFHCFNDA_03589 7.9e-58 yhjD
AFHCFNDA_03590 3.1e-27 yhjC S Protein of unknown function (DUF3311)
AFHCFNDA_03591 1.2e-261 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFHCFNDA_03592 3.3e-47 S Belongs to the UPF0145 family
AFHCFNDA_03593 7.8e-42 yhjA S Excalibur calcium-binding domain
AFHCFNDA_03594 1.2e-121 yrpD S Domain of unknown function, YrpD
AFHCFNDA_03595 6.1e-171 els S Acetyltransferase, GNAT family
AFHCFNDA_03596 4.1e-57 frataxin S Domain of unknown function (DU1801)
AFHCFNDA_03597 4.2e-109 comK K Competence transcription factor
AFHCFNDA_03598 1.2e-30 yhzC S IDEAL
AFHCFNDA_03599 1.4e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_03600 1e-262 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
AFHCFNDA_03601 2.4e-197 hemAT NT chemotaxis protein
AFHCFNDA_03602 3.1e-85 bioY S BioY family
AFHCFNDA_03603 6.2e-263 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
AFHCFNDA_03604 1.4e-193 vraB 2.3.1.9 I Belongs to the thiolase family
AFHCFNDA_03605 2.7e-100 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
AFHCFNDA_03606 7e-129 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
AFHCFNDA_03607 1.6e-200 aprE 3.4.21.62 O Belongs to the peptidase S8 family
AFHCFNDA_03608 5.4e-231 yhfN 3.4.24.84 O Peptidase M48
AFHCFNDA_03609 8.1e-64 yhfM
AFHCFNDA_03610 1.7e-295 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
AFHCFNDA_03611 5.7e-107 yhfK GM NmrA-like family
AFHCFNDA_03612 1.7e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
AFHCFNDA_03613 6.2e-134 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
AFHCFNDA_03614 1.2e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFHCFNDA_03615 1.5e-194 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
AFHCFNDA_03617 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFHCFNDA_03618 1.6e-255 yhgE S YhgE Pip N-terminal domain protein
AFHCFNDA_03619 3.5e-100 yhgD K Transcriptional regulator
AFHCFNDA_03620 6.6e-273 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
AFHCFNDA_03621 1.7e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
AFHCFNDA_03622 1.9e-198 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AFHCFNDA_03623 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
AFHCFNDA_03624 6e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
AFHCFNDA_03625 2.5e-237 yhfA C membrane
AFHCFNDA_03626 1.4e-215 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
AFHCFNDA_03627 1.1e-116 ecsC S EcsC protein family
AFHCFNDA_03628 5.7e-217 ecsB U ABC transporter
AFHCFNDA_03629 4.4e-135 ecsA V transporter (ATP-binding protein)
AFHCFNDA_03630 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
AFHCFNDA_03631 1.5e-197 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AFHCFNDA_03632 1.3e-74 trpP S Tryptophan transporter TrpP
AFHCFNDA_03633 2e-17
AFHCFNDA_03634 9e-38 yhaH S YtxH-like protein
AFHCFNDA_03635 1.5e-109 hpr K Negative regulator of protease production and sporulation
AFHCFNDA_03636 9.9e-55 yhaI S Protein of unknown function (DUF1878)
AFHCFNDA_03637 1e-93 yhaK S Putative zincin peptidase
AFHCFNDA_03638 3.2e-113 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
AFHCFNDA_03639 2.3e-31 yhaL S Sporulation protein YhaL
AFHCFNDA_03640 1.1e-175 yhaM L Shows a 3'-5' exoribonuclease activity
AFHCFNDA_03641 0.0 yhaN L AAA domain
AFHCFNDA_03642 9.1e-231 yhaO L DNA repair exonuclease
AFHCFNDA_03643 1.1e-202 yhaP CP COG1668 ABC-type Na efflux pump, permease component
AFHCFNDA_03644 5.9e-163 yhaQ S ABC transporter, ATP-binding protein
AFHCFNDA_03645 1.2e-14 S YhzD-like protein
AFHCFNDA_03646 4.2e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
AFHCFNDA_03648 1.9e-86 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
AFHCFNDA_03649 2.5e-204 yhaU P COG0475 Kef-type K transport systems, membrane components
AFHCFNDA_03650 1.1e-245 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
AFHCFNDA_03651 1.1e-291 hemZ H coproporphyrinogen III oxidase
AFHCFNDA_03652 2.7e-152 yhaX S haloacid dehalogenase-like hydrolase
AFHCFNDA_03653 6.3e-52 yheA S Belongs to the UPF0342 family
AFHCFNDA_03654 8.5e-199 yheB S Belongs to the UPF0754 family
AFHCFNDA_03655 6.1e-202 yheC HJ YheC/D like ATP-grasp
AFHCFNDA_03656 1.1e-248 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
AFHCFNDA_03657 1.9e-35 yheE S Family of unknown function (DUF5342)
AFHCFNDA_03658 8.4e-28 sspB S spore protein
AFHCFNDA_03660 3.2e-99 yheG GM NAD(P)H-binding
AFHCFNDA_03661 1.9e-37 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
AFHCFNDA_03662 6.2e-310 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
AFHCFNDA_03663 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
AFHCFNDA_03664 1.3e-82 T universal stress protein
AFHCFNDA_03665 4.1e-90 ymcC S Membrane
AFHCFNDA_03666 3.7e-97 pksA K Transcriptional regulator
AFHCFNDA_03667 3.9e-148 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
AFHCFNDA_03668 1.4e-150 yheN G deacetylase
AFHCFNDA_03669 9.1e-133 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
AFHCFNDA_03670 2.1e-197 yhdY M Mechanosensitive ion channel
AFHCFNDA_03672 1.2e-121 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
AFHCFNDA_03673 3.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFHCFNDA_03674 8.8e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AFHCFNDA_03675 4.2e-248 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
AFHCFNDA_03676 3.3e-228 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
AFHCFNDA_03677 1.5e-217 yhdR 2.6.1.1 E Aminotransferase
AFHCFNDA_03678 1.8e-69 cueR K transcriptional
AFHCFNDA_03679 4e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
AFHCFNDA_03680 5.8e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
AFHCFNDA_03681 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
AFHCFNDA_03682 3.2e-195 yhdL S Sigma factor regulator N-terminal
AFHCFNDA_03683 8.1e-45 yhdK S Sigma-M inhibitor protein
AFHCFNDA_03684 1.6e-196 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
AFHCFNDA_03685 6.1e-247 yhdG E amino acid
AFHCFNDA_03686 3.1e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
AFHCFNDA_03687 1.6e-197 citA 2.3.3.1 C Belongs to the citrate synthase family
AFHCFNDA_03688 1.3e-157 citR K Transcriptional regulator
AFHCFNDA_03689 9.5e-123 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
AFHCFNDA_03690 6.2e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
AFHCFNDA_03691 4.2e-264 ycgB S Stage V sporulation protein R
AFHCFNDA_03692 3.5e-248 ygxB M Conserved TM helix
AFHCFNDA_03693 2.6e-71 nsrR K Transcriptional regulator
AFHCFNDA_03694 2.3e-201 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
AFHCFNDA_03695 1.3e-51 yhdC S Protein of unknown function (DUF3889)
AFHCFNDA_03696 8e-38 yhdB S YhdB-like protein
AFHCFNDA_03697 2.7e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
AFHCFNDA_03698 2e-107 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
AFHCFNDA_03699 1.3e-194 yhcY 2.7.13.3 T Histidine kinase
AFHCFNDA_03700 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
AFHCFNDA_03701 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AFHCFNDA_03702 8.9e-289 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFHCFNDA_03703 1.7e-143 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
AFHCFNDA_03704 1e-99 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
AFHCFNDA_03705 2.6e-255 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFHCFNDA_03706 1.9e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
AFHCFNDA_03707 1e-122 yhcW 5.4.2.6 S hydrolase
AFHCFNDA_03708 8.4e-67 yhcV S COG0517 FOG CBS domain
AFHCFNDA_03709 2.6e-62 yhcU S Family of unknown function (DUF5365)
AFHCFNDA_03710 3.9e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
AFHCFNDA_03711 6.9e-99 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
AFHCFNDA_03712 1.5e-297 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
AFHCFNDA_03713 9.4e-113 yhcQ M Spore coat protein
AFHCFNDA_03714 1.3e-154 yhcP
AFHCFNDA_03715 6.3e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
AFHCFNDA_03716 4.4e-38 yhcM
AFHCFNDA_03717 6.9e-40 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
AFHCFNDA_03718 8.6e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
AFHCFNDA_03719 4e-182 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
AFHCFNDA_03720 4.5e-125 metQ M Belongs to the nlpA lipoprotein family
AFHCFNDA_03721 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
AFHCFNDA_03722 7.9e-158 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
AFHCFNDA_03723 1.9e-164 yhcH V ABC transporter, ATP-binding protein
AFHCFNDA_03724 2.8e-115 yhcG V ABC transporter, ATP-binding protein
AFHCFNDA_03725 1.7e-58 yhcF K Transcriptional regulator
AFHCFNDA_03726 3.6e-52
AFHCFNDA_03727 5.3e-49 yhcC
AFHCFNDA_03728 1e-98 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
AFHCFNDA_03729 4.1e-284 yhcA EGP Major facilitator Superfamily
AFHCFNDA_03730 4.4e-96 yhbJ V COG1566 Multidrug resistance efflux pump
AFHCFNDA_03731 1.6e-71 yhbI K DNA-binding transcription factor activity
AFHCFNDA_03732 1.7e-213 yhbH S Belongs to the UPF0229 family
AFHCFNDA_03733 0.0 prkA T Ser protein kinase
AFHCFNDA_03735 1.3e-56 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
AFHCFNDA_03736 3.6e-54 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
AFHCFNDA_03737 3.2e-102 yhbD K Protein of unknown function (DUF4004)
AFHCFNDA_03738 2.2e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
AFHCFNDA_03739 2.9e-168 yhbB S Putative amidase domain
AFHCFNDA_03740 6.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AFHCFNDA_03741 4.2e-107 yhzB S B3/4 domain
AFHCFNDA_03743 1.8e-22 K Transcriptional regulator
AFHCFNDA_03744 8.9e-78 ygaO
AFHCFNDA_03745 3.9e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AFHCFNDA_03747 1.8e-212 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
AFHCFNDA_03748 2.4e-142 ssuC P ABC transporter (permease)
AFHCFNDA_03749 5e-171 ssuA M Sulfonate ABC transporter
AFHCFNDA_03750 4.3e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
AFHCFNDA_03751 4.7e-179 S Amidohydrolase
AFHCFNDA_03752 4e-286 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
AFHCFNDA_03753 2.9e-131 oppF3 E Belongs to the ABC transporter superfamily
AFHCFNDA_03754 9.8e-135 oppD3 P Belongs to the ABC transporter superfamily
AFHCFNDA_03755 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
AFHCFNDA_03756 3.5e-145 appB P Binding-protein-dependent transport system inner membrane component
AFHCFNDA_03757 6.4e-230 oppA5 E PFAM extracellular solute-binding protein family 5
AFHCFNDA_03759 1.3e-246 ygaK C Berberine and berberine like
AFHCFNDA_03760 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AFHCFNDA_03761 1.8e-122 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
AFHCFNDA_03762 5.9e-275 C Na+/H+ antiporter family
AFHCFNDA_03766 1.6e-08
AFHCFNDA_03770 4e-246 iolT EGP Major facilitator Superfamily
AFHCFNDA_03771 5.1e-07 S YopX protein
AFHCFNDA_03776 1e-15
AFHCFNDA_03778 5.9e-117 S HTH-like domain
AFHCFNDA_03779 3.3e-43 S transposition, DNA-mediated
AFHCFNDA_03780 1.2e-42 S dUTPase
AFHCFNDA_03781 2.2e-194 yoaB EGP Major facilitator Superfamily
AFHCFNDA_03782 1.2e-264 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
AFHCFNDA_03783 1.5e-186 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFHCFNDA_03784 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AFHCFNDA_03785 5.7e-27 yoaF
AFHCFNDA_03787 1.1e-93 hpr K helix_turn_helix multiple antibiotic resistance protein
AFHCFNDA_03788 1.1e-28
AFHCFNDA_03791 4.6e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
AFHCFNDA_03792 3.4e-121 yobQ K helix_turn_helix, arabinose operon control protein
AFHCFNDA_03793 7e-85 yobS K Transcriptional regulator
AFHCFNDA_03794 8.8e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
AFHCFNDA_03795 2.1e-91 yobW
AFHCFNDA_03796 7.6e-55 czrA K transcriptional
AFHCFNDA_03797 3.3e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
AFHCFNDA_03798 1.4e-90 yozB S membrane
AFHCFNDA_03799 1.9e-133 yocB J Protein required for attachment to host cells
AFHCFNDA_03800 3.4e-91 yocC
AFHCFNDA_03801 5.3e-181 yocD 3.4.17.13 V peptidase S66
AFHCFNDA_03803 2.1e-112 yocH CBM50 M COG1388 FOG LysM repeat
AFHCFNDA_03804 0.0 recQ 3.6.4.12 L DNA helicase
AFHCFNDA_03806 1.1e-110 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AFHCFNDA_03807 2e-56 dksA T general stress protein
AFHCFNDA_03808 6.3e-10 yocL
AFHCFNDA_03809 9.8e-09
AFHCFNDA_03810 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
AFHCFNDA_03811 7.5e-29 yozN
AFHCFNDA_03812 5.5e-36 yocN
AFHCFNDA_03813 2.4e-56 yozO S Bacterial PH domain
AFHCFNDA_03815 1.6e-31 yozC
AFHCFNDA_03816 5.1e-284 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
AFHCFNDA_03817 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
AFHCFNDA_03818 8.1e-162 sodA 1.15.1.1 P Superoxide dismutase
AFHCFNDA_03819 7.1e-229 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
AFHCFNDA_03820 1.8e-157 yocS S -transporter
AFHCFNDA_03821 8e-123 S Metallo-beta-lactamase superfamily
AFHCFNDA_03822 2.9e-184 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
AFHCFNDA_03823 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
AFHCFNDA_03824 0.0 yojO P Von Willebrand factor
AFHCFNDA_03825 6.5e-162 yojN S ATPase family associated with various cellular activities (AAA)
AFHCFNDA_03826 1.2e-98 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AFHCFNDA_03827 2.1e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
AFHCFNDA_03828 5.1e-218 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
AFHCFNDA_03829 2.3e-105 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AFHCFNDA_03831 1.1e-232 norM V Multidrug efflux pump
AFHCFNDA_03832 6.2e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
AFHCFNDA_03833 9.6e-126 yojG S deacetylase
AFHCFNDA_03834 3.7e-60 yojF S Protein of unknown function (DUF1806)
AFHCFNDA_03835 6.4e-23
AFHCFNDA_03836 2.6e-158 rarD S -transporter
AFHCFNDA_03837 8.9e-78 yozR S COG0071 Molecular chaperone (small heat shock protein)
AFHCFNDA_03839 6.8e-63 yodA S tautomerase
AFHCFNDA_03840 3.5e-52 yodB K transcriptional
AFHCFNDA_03841 2.8e-103 yodC C nitroreductase
AFHCFNDA_03842 5.3e-107 mhqD S Carboxylesterase
AFHCFNDA_03843 3.8e-54 yodE E COG0346 Lactoylglutathione lyase and related lyases
AFHCFNDA_03844 1.1e-104 yodE E COG0346 Lactoylglutathione lyase and related lyases
AFHCFNDA_03845 3.1e-19 S Protein of unknown function (DUF3311)
AFHCFNDA_03846 3.2e-262 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFHCFNDA_03847 4.3e-267 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
AFHCFNDA_03848 1.6e-282 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
AFHCFNDA_03849 3.8e-128 yydK K Transcriptional regulator
AFHCFNDA_03850 5.5e-248 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
AFHCFNDA_03851 2.2e-120 yodH Q Methyltransferase
AFHCFNDA_03852 1e-19 yodI
AFHCFNDA_03853 7.6e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
AFHCFNDA_03854 7.7e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
AFHCFNDA_03856 3.3e-55 yodL S YodL-like
AFHCFNDA_03857 4.4e-101 yodM 3.6.1.27 I Acid phosphatase homologues
AFHCFNDA_03858 1.8e-23 yozD S YozD-like protein
AFHCFNDA_03860 5.6e-121 yodN
AFHCFNDA_03861 6.1e-51 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
AFHCFNDA_03862 3.4e-35 yozE S Belongs to the UPF0346 family
AFHCFNDA_03863 1.1e-43 yokU S YokU-like protein, putative antitoxin
AFHCFNDA_03864 1.2e-274 kamA 5.4.3.2 E lysine 2,3-aminomutase
AFHCFNDA_03865 1.4e-140 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
AFHCFNDA_03866 1e-248 yodQ 3.5.1.16 E Acetylornithine deacetylase
AFHCFNDA_03867 2.7e-118 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
AFHCFNDA_03868 1.5e-121 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AFHCFNDA_03869 3e-235 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AFHCFNDA_03871 5.4e-64 yosT L Bacterial transcription activator, effector binding domain
AFHCFNDA_03873 1.3e-137 yiiD K acetyltransferase
AFHCFNDA_03874 7e-226 cgeD M maturation of the outermost layer of the spore
AFHCFNDA_03875 1.4e-36 cgeC
AFHCFNDA_03876 3.1e-48 cgeA
AFHCFNDA_03877 7.7e-169 cgeB S Spore maturation protein
AFHCFNDA_03878 3.7e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
AFHCFNDA_03879 1.2e-69 4.2.1.115 GM Polysaccharide biosynthesis protein
AFHCFNDA_03882 1.9e-121 lldD 1.13.12.4 C FMN-dependent dehydrogenase
AFHCFNDA_03884 1.9e-13 S Regulatory protein YrvL
AFHCFNDA_03885 6.4e-211 yokA L Recombinase
AFHCFNDA_03886 1.2e-100 4.2.1.115 GM Polysaccharide biosynthesis protein
AFHCFNDA_03887 4.1e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
AFHCFNDA_03888 4.3e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AFHCFNDA_03889 8.9e-66 ypoP K transcriptional
AFHCFNDA_03890 1.7e-94 ypmS S protein conserved in bacteria
AFHCFNDA_03891 9.5e-130 ypmR E GDSL-like Lipase/Acylhydrolase
AFHCFNDA_03892 2e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
AFHCFNDA_03893 7.5e-39 ypmP S Protein of unknown function (DUF2535)
AFHCFNDA_03894 1.3e-240 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AFHCFNDA_03895 3.8e-163 pspF K Transcriptional regulator
AFHCFNDA_03896 6.6e-108 hlyIII S protein, Hemolysin III
AFHCFNDA_03897 1.7e-108 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
AFHCFNDA_03898 7.8e-85 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFHCFNDA_03899 2.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFHCFNDA_03900 3e-110 ypjP S YpjP-like protein
AFHCFNDA_03901 2.9e-126 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
AFHCFNDA_03902 1.7e-75 yphP S Belongs to the UPF0403 family
AFHCFNDA_03903 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
AFHCFNDA_03904 6e-152 ypgR C COG0694 Thioredoxin-like proteins and domains
AFHCFNDA_03905 2.3e-89 ypgQ S phosphohydrolase
AFHCFNDA_03906 2.1e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
AFHCFNDA_03908 2.8e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AFHCFNDA_03909 3e-212 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
AFHCFNDA_03910 1e-30 cspD K Cold-shock protein
AFHCFNDA_03911 6.3e-11 degR
AFHCFNDA_03912 2.3e-35 S Protein of unknown function (DUF2564)
AFHCFNDA_03913 3.7e-27 ypeQ S Zinc-finger
AFHCFNDA_03914 2e-118 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
AFHCFNDA_03915 5.2e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AFHCFNDA_03916 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
AFHCFNDA_03918 8e-160 polA 2.7.7.7 L 5'3' exonuclease
AFHCFNDA_03920 3.7e-33 ypbS S Protein of unknown function (DUF2533)
AFHCFNDA_03921 0.0 ypbR S Dynamin family
AFHCFNDA_03922 4.8e-85 ypbQ S protein conserved in bacteria
AFHCFNDA_03923 1.2e-194 bcsA Q Naringenin-chalcone synthase
AFHCFNDA_03924 2e-101 J Acetyltransferase (GNAT) domain
AFHCFNDA_03925 6.6e-45 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
AFHCFNDA_03926 2.4e-07 S Bacillus cereus group antimicrobial protein
AFHCFNDA_03927 5.7e-158 pbuX F xanthine
AFHCFNDA_03929 1.1e-90 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
AFHCFNDA_03942 3.9e-87
AFHCFNDA_03946 8.3e-29 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AFHCFNDA_03947 3.7e-151 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFHCFNDA_03951 8.8e-72 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
AFHCFNDA_03952 7.4e-11 O Glutaredoxin
AFHCFNDA_03953 7.2e-26
AFHCFNDA_03954 8.7e-44 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFHCFNDA_03955 2.3e-82 L HNH endonuclease
AFHCFNDA_03956 9.1e-104 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFHCFNDA_03957 6e-44 tnpIS3 L Transposase
AFHCFNDA_03960 2e-08
AFHCFNDA_03970 4.7e-171 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFHCFNDA_03971 8e-41 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFHCFNDA_03972 2.2e-115 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AFHCFNDA_03973 7.9e-67 S NrdI Flavodoxin like
AFHCFNDA_03976 1.5e-12 larC 4.99.1.12 FJ Protein conserved in bacteria
AFHCFNDA_03984 6.9e-164 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
AFHCFNDA_03985 2e-86 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
AFHCFNDA_03986 3.9e-71 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
AFHCFNDA_03989 3.3e-23 DR0488 S protein conserved in bacteria
AFHCFNDA_03990 0.0 S Bacterial DNA polymerase III alpha subunit
AFHCFNDA_03991 9.3e-306 recJ L Single-stranded-DNA-specific exonuclease RecJ
AFHCFNDA_03992 1.1e-203 L DNA primase activity
AFHCFNDA_03993 3.4e-211 3.6.4.12 J DnaB-like helicase C terminal domain
AFHCFNDA_03994 5.6e-80
AFHCFNDA_03995 2.6e-172 L AAA domain
AFHCFNDA_03996 3.6e-155
AFHCFNDA_04000 6e-220 M Parallel beta-helix repeats
AFHCFNDA_04001 1.6e-85 S Pfam:DUF867
AFHCFNDA_04004 1.6e-160
AFHCFNDA_04005 1.4e-09 S YopX protein
AFHCFNDA_04008 2.6e-126 yoqW S Belongs to the SOS response-associated peptidase family
AFHCFNDA_04009 5.1e-137 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
AFHCFNDA_04010 7.6e-65
AFHCFNDA_04012 2.7e-61
AFHCFNDA_04014 1.4e-16
AFHCFNDA_04018 5e-71 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
AFHCFNDA_04019 2.8e-24
AFHCFNDA_04023 9.2e-62 2.1.1.294, 2.7.1.181 N bacterial-type flagellum assembly
AFHCFNDA_04027 9.8e-23
AFHCFNDA_04030 5.6e-07 S YopX protein
AFHCFNDA_04031 3.4e-40
AFHCFNDA_04035 2.4e-12 K Transcriptional regulator
AFHCFNDA_04036 9.8e-34
AFHCFNDA_04037 4.9e-185
AFHCFNDA_04038 1.2e-37 L Belongs to the 'phage' integrase family
AFHCFNDA_04044 4.6e-75
AFHCFNDA_04045 9.3e-46
AFHCFNDA_04055 8e-23 K Cro/C1-type HTH DNA-binding domain
AFHCFNDA_04056 3.5e-68 yoaW
AFHCFNDA_04057 2.8e-21 I Acyltransferase family
AFHCFNDA_04059 0.0 S ATP-dependent DNA helicase activity
AFHCFNDA_04061 1.9e-140 S serine-type endopeptidase activity
AFHCFNDA_04062 3.4e-83 S DNA binding
AFHCFNDA_04063 2.4e-215
AFHCFNDA_04066 1.5e-59 ftsZ D Tubulin/FtsZ family, GTPase domain
AFHCFNDA_04070 0.0
AFHCFNDA_04071 2.7e-34 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
AFHCFNDA_04074 8.7e-218 S Calcineurin-like phosphoesterase superfamily domain
AFHCFNDA_04078 1.3e-17
AFHCFNDA_04079 1.8e-94
AFHCFNDA_04080 1.8e-18
AFHCFNDA_04081 1.2e-38
AFHCFNDA_04083 3.1e-68
AFHCFNDA_04086 2.3e-55
AFHCFNDA_04087 6.3e-85
AFHCFNDA_04088 3e-96
AFHCFNDA_04089 2.4e-62
AFHCFNDA_04091 8.8e-49
AFHCFNDA_04092 1e-54 S Domain of unknown function (DUF2479)
AFHCFNDA_04093 2.7e-13
AFHCFNDA_04095 1.2e-83 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
AFHCFNDA_04096 1.6e-58
AFHCFNDA_04097 3.9e-48
AFHCFNDA_04098 2.4e-173 xerH A Belongs to the 'phage' integrase family
AFHCFNDA_04100 7.2e-17
AFHCFNDA_04101 7.1e-83 KLT Protein tyrosine kinase
AFHCFNDA_04104 6.6e-52
AFHCFNDA_04105 0.0 S peptidoglycan catabolic process
AFHCFNDA_04106 7.2e-85 S Phage tail protein
AFHCFNDA_04107 4.8e-194 S Pfam Transposase IS66
AFHCFNDA_04108 2e-93
AFHCFNDA_04109 3.5e-269 M Pectate lyase superfamily protein
AFHCFNDA_04110 6.1e-50 M Ami_2
AFHCFNDA_04112 2.3e-32 S Bacteriophage holin
AFHCFNDA_04115 1.1e-87 S response regulator aspartate phosphatase
AFHCFNDA_04117 2.7e-222 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AFHCFNDA_04118 4.2e-37 S YolD-like protein
AFHCFNDA_04121 1.3e-09
AFHCFNDA_04124 9.5e-09 ddpX 3.4.13.22 F protein conserved in bacteria
AFHCFNDA_04126 5.2e-07 K transcriptional
AFHCFNDA_04128 5.5e-57 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
AFHCFNDA_04129 1.4e-55 araQ G transport system permease
AFHCFNDA_04130 2.8e-163 araP P PFAM binding-protein-dependent transport systems inner membrane component
AFHCFNDA_04131 4.3e-247 araN G carbohydrate transport
AFHCFNDA_04132 8.4e-185 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
AFHCFNDA_04134 2e-136 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
AFHCFNDA_04135 7.1e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
AFHCFNDA_04136 2.2e-307 araB 2.7.1.16 C Belongs to the ribulokinase family
AFHCFNDA_04137 3.3e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
AFHCFNDA_04138 1.3e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
AFHCFNDA_04139 4e-206 ysdC G COG1363 Cellulase M and related proteins
AFHCFNDA_04140 2.6e-62 ysdB S Sigma-w pathway protein YsdB
AFHCFNDA_04141 1.8e-38 ysdA S Membrane
AFHCFNDA_04142 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AFHCFNDA_04143 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
AFHCFNDA_04144 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AFHCFNDA_04145 2.7e-107 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
AFHCFNDA_04146 5.5e-37 lrgA S effector of murein hydrolase LrgA
AFHCFNDA_04147 1e-128 lytT T COG3279 Response regulator of the LytR AlgR family
AFHCFNDA_04148 0.0 lytS 2.7.13.3 T Histidine kinase
AFHCFNDA_04149 4.1e-147 ysaA S HAD-hyrolase-like
AFHCFNDA_04150 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFHCFNDA_04151 1.6e-149 ytxC S YtxC-like family
AFHCFNDA_04152 1.8e-105 ytxB S SNARE associated Golgi protein
AFHCFNDA_04153 2.9e-168 dnaI L Primosomal protein DnaI
AFHCFNDA_04154 7.7e-250 dnaB L Membrane attachment protein
AFHCFNDA_04155 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AFHCFNDA_04156 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AFHCFNDA_04157 1.3e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
AFHCFNDA_04158 1.6e-64 ytcD K Transcriptional regulator
AFHCFNDA_04159 5.8e-198 ytbD EGP Major facilitator Superfamily
AFHCFNDA_04160 1.5e-155 ytbE S reductase
AFHCFNDA_04161 3.9e-94 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AFHCFNDA_04162 2.6e-104 ytaF P Probably functions as a manganese efflux pump
AFHCFNDA_04163 2.7e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
AFHCFNDA_04164 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AFHCFNDA_04165 2.6e-308 phoR 2.7.13.3 T Signal transduction histidine kinase
AFHCFNDA_04166 5e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
AFHCFNDA_04167 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
AFHCFNDA_04168 2e-241 icd 1.1.1.42 C isocitrate
AFHCFNDA_04169 8.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)