ORF_ID e_value Gene_name EC_number CAZy COGs Description
NHPBOKKD_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NHPBOKKD_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NHPBOKKD_00003 2.4e-33 yaaA S S4 domain
NHPBOKKD_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NHPBOKKD_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
NHPBOKKD_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHPBOKKD_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NHPBOKKD_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00011 2.7e-182 yaaC S YaaC-like Protein
NHPBOKKD_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NHPBOKKD_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NHPBOKKD_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NHPBOKKD_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NHPBOKKD_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NHPBOKKD_00017 1.3e-09
NHPBOKKD_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NHPBOKKD_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NHPBOKKD_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
NHPBOKKD_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
NHPBOKKD_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NHPBOKKD_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHPBOKKD_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NHPBOKKD_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NHPBOKKD_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NHPBOKKD_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NHPBOKKD_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
NHPBOKKD_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NHPBOKKD_00033 4.5e-203 yaaN P Belongs to the TelA family
NHPBOKKD_00034 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NHPBOKKD_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NHPBOKKD_00036 2.2e-54 yaaQ S protein conserved in bacteria
NHPBOKKD_00037 1.5e-71 yaaR S protein conserved in bacteria
NHPBOKKD_00038 2.2e-182 holB 2.7.7.7 L DNA polymerase III
NHPBOKKD_00039 2.1e-146 yaaT S stage 0 sporulation protein
NHPBOKKD_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
NHPBOKKD_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
NHPBOKKD_00042 1.5e-49 yazA L endonuclease containing a URI domain
NHPBOKKD_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NHPBOKKD_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NHPBOKKD_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NHPBOKKD_00046 1.8e-144 tatD L hydrolase, TatD
NHPBOKKD_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
NHPBOKKD_00048 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NHPBOKKD_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NHPBOKKD_00050 3.3e-137 yabG S peptidase
NHPBOKKD_00051 7.8e-39 veg S protein conserved in bacteria
NHPBOKKD_00052 8.3e-27 sspF S DNA topological change
NHPBOKKD_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NHPBOKKD_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NHPBOKKD_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NHPBOKKD_00056 1e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NHPBOKKD_00057 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NHPBOKKD_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NHPBOKKD_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NHPBOKKD_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NHPBOKKD_00061 2.4e-39 yabK S Peptide ABC transporter permease
NHPBOKKD_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NHPBOKKD_00063 1.5e-92 spoVT K stage V sporulation protein
NHPBOKKD_00064 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPBOKKD_00065 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NHPBOKKD_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NHPBOKKD_00067 1.5e-49 yabP S Sporulation protein YabP
NHPBOKKD_00068 3.9e-108 yabQ S spore cortex biosynthesis protein
NHPBOKKD_00069 1.1e-44 divIC D Septum formation initiator
NHPBOKKD_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NHPBOKKD_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NHPBOKKD_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NHPBOKKD_00075 6.7e-187 KLT serine threonine protein kinase
NHPBOKKD_00076 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NHPBOKKD_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NHPBOKKD_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NHPBOKKD_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NHPBOKKD_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NHPBOKKD_00081 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NHPBOKKD_00082 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHPBOKKD_00083 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHPBOKKD_00084 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NHPBOKKD_00085 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NHPBOKKD_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NHPBOKKD_00087 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NHPBOKKD_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NHPBOKKD_00089 4.1e-30 yazB K transcriptional
NHPBOKKD_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHPBOKKD_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NHPBOKKD_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00097 2e-08
NHPBOKKD_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00103 2.9e-76 ctsR K Belongs to the CtsR family
NHPBOKKD_00104 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NHPBOKKD_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NHPBOKKD_00106 0.0 clpC O Belongs to the ClpA ClpB family
NHPBOKKD_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NHPBOKKD_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NHPBOKKD_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NHPBOKKD_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NHPBOKKD_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NHPBOKKD_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NHPBOKKD_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
NHPBOKKD_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHPBOKKD_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NHPBOKKD_00116 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHPBOKKD_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NHPBOKKD_00118 1.5e-115 sigH K Belongs to the sigma-70 factor family
NHPBOKKD_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NHPBOKKD_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
NHPBOKKD_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NHPBOKKD_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NHPBOKKD_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NHPBOKKD_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NHPBOKKD_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
NHPBOKKD_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPBOKKD_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPBOKKD_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NHPBOKKD_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NHPBOKKD_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NHPBOKKD_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NHPBOKKD_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NHPBOKKD_00133 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NHPBOKKD_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NHPBOKKD_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NHPBOKKD_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
NHPBOKKD_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NHPBOKKD_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NHPBOKKD_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NHPBOKKD_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NHPBOKKD_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NHPBOKKD_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NHPBOKKD_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NHPBOKKD_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NHPBOKKD_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NHPBOKKD_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NHPBOKKD_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NHPBOKKD_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHPBOKKD_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NHPBOKKD_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NHPBOKKD_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NHPBOKKD_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NHPBOKKD_00153 1.9e-23 rpmD J Ribosomal protein L30
NHPBOKKD_00154 1.8e-72 rplO J binds to the 23S rRNA
NHPBOKKD_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NHPBOKKD_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NHPBOKKD_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NHPBOKKD_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NHPBOKKD_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NHPBOKKD_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NHPBOKKD_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NHPBOKKD_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NHPBOKKD_00163 3.6e-58 rplQ J Ribosomal protein L17
NHPBOKKD_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPBOKKD_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPBOKKD_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NHPBOKKD_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NHPBOKKD_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NHPBOKKD_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NHPBOKKD_00170 8.2e-145 ybaJ Q Methyltransferase domain
NHPBOKKD_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NHPBOKKD_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPBOKKD_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NHPBOKKD_00174 1.2e-84 gerD
NHPBOKKD_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NHPBOKKD_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NHPBOKKD_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00178 3.3e-39 S COG NOG15344 non supervised orthologous group
NHPBOKKD_00181 2e-08
NHPBOKKD_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00186 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00187 1.1e-232 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NHPBOKKD_00189 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
NHPBOKKD_00190 2.2e-142 ybbA S Putative esterase
NHPBOKKD_00191 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_00192 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_00193 7.2e-167 feuA P Iron-uptake system-binding protein
NHPBOKKD_00194 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NHPBOKKD_00195 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
NHPBOKKD_00196 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NHPBOKKD_00197 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NHPBOKKD_00198 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPBOKKD_00199 1.1e-150 ybbH K transcriptional
NHPBOKKD_00200 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NHPBOKKD_00201 6.4e-87 ybbJ J acetyltransferase
NHPBOKKD_00202 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NHPBOKKD_00208 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_00209 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NHPBOKKD_00210 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHPBOKKD_00211 3e-225 ybbR S protein conserved in bacteria
NHPBOKKD_00212 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NHPBOKKD_00213 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NHPBOKKD_00214 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NHPBOKKD_00215 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
NHPBOKKD_00216 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHPBOKKD_00217 3.6e-219 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NHPBOKKD_00218 0.0 ybcC S Belongs to the UPF0753 family
NHPBOKKD_00219 3.7e-96 can 4.2.1.1 P carbonic anhydrase
NHPBOKKD_00220 3.9e-47
NHPBOKKD_00221 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NHPBOKKD_00222 5.1e-50 ybzH K Helix-turn-helix domain
NHPBOKKD_00223 2e-203 ybcL EGP Major facilitator Superfamily
NHPBOKKD_00225 9.1e-239 J 4Fe-4S single cluster domain
NHPBOKKD_00226 1.6e-277 V CAAX protease self-immunity
NHPBOKKD_00227 1.9e-135 skfE V ABC transporter
NHPBOKKD_00228 4e-248 skfF S ABC transporter
NHPBOKKD_00229 7.8e-91 C HEAT repeats
NHPBOKKD_00230 9.6e-79 txn CO Thioredoxin-like
NHPBOKKD_00231 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHPBOKKD_00232 1.5e-123 T Transcriptional regulatory protein, C terminal
NHPBOKKD_00233 1.8e-173 T His Kinase A (phospho-acceptor) domain
NHPBOKKD_00235 1.6e-140 KLT Protein tyrosine kinase
NHPBOKKD_00236 4.8e-154 ybdN
NHPBOKKD_00237 1.5e-217 ybdO S Domain of unknown function (DUF4885)
NHPBOKKD_00238 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NHPBOKKD_00239 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
NHPBOKKD_00240 4.9e-30 ybxH S Family of unknown function (DUF5370)
NHPBOKKD_00241 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
NHPBOKKD_00242 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NHPBOKKD_00243 4.9e-41 ybyB
NHPBOKKD_00244 1.8e-290 ybeC E amino acid
NHPBOKKD_00245 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHPBOKKD_00246 7.3e-258 glpT G -transporter
NHPBOKKD_00247 2.9e-35 S Protein of unknown function (DUF2651)
NHPBOKKD_00248 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
NHPBOKKD_00249 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
NHPBOKKD_00251 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NHPBOKKD_00252 8.8e-162 ybfH EG EamA-like transporter family
NHPBOKKD_00253 2.3e-145 msmR K AraC-like ligand binding domain
NHPBOKKD_00254 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NHPBOKKD_00255 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NHPBOKKD_00257 2.5e-169 S Alpha/beta hydrolase family
NHPBOKKD_00258 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHPBOKKD_00259 2.7e-85 ybfM S SNARE associated Golgi protein
NHPBOKKD_00260 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NHPBOKKD_00261 3.2e-46 ybfN
NHPBOKKD_00262 4.3e-258 S Erythromycin esterase
NHPBOKKD_00263 6.7e-167 ybfP K Transcriptional regulator
NHPBOKKD_00264 3.9e-192 yceA S Belongs to the UPF0176 family
NHPBOKKD_00265 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPBOKKD_00266 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPBOKKD_00267 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHPBOKKD_00268 4.9e-128 K UTRA
NHPBOKKD_00270 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NHPBOKKD_00271 6.7e-262 mmuP E amino acid
NHPBOKKD_00272 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NHPBOKKD_00273 2.3e-257 agcS E Sodium alanine symporter
NHPBOKKD_00274 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
NHPBOKKD_00275 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
NHPBOKKD_00276 9e-170 glnL T Regulator
NHPBOKKD_00277 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NHPBOKKD_00278 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPBOKKD_00279 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NHPBOKKD_00280 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NHPBOKKD_00281 1.5e-124 ycbG K FCD
NHPBOKKD_00282 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
NHPBOKKD_00283 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
NHPBOKKD_00284 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NHPBOKKD_00285 7.3e-172 eamA1 EG spore germination
NHPBOKKD_00286 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_00287 2.4e-170 T PhoQ Sensor
NHPBOKKD_00288 4.8e-168 ycbN V ABC transporter, ATP-binding protein
NHPBOKKD_00289 2.1e-115 S ABC-2 family transporter protein
NHPBOKKD_00290 8.2e-53 ycbP S Protein of unknown function (DUF2512)
NHPBOKKD_00291 1.3e-78 sleB 3.5.1.28 M Cell wall
NHPBOKKD_00292 6.6e-136 ycbR T vWA found in TerF C terminus
NHPBOKKD_00293 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NHPBOKKD_00294 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHPBOKKD_00295 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHPBOKKD_00296 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NHPBOKKD_00297 6.2e-210 ycbU E Selenocysteine lyase
NHPBOKKD_00298 5.8e-229 lmrB EGP the major facilitator superfamily
NHPBOKKD_00299 4.8e-102 yxaF K Transcriptional regulator
NHPBOKKD_00300 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NHPBOKKD_00301 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHPBOKKD_00302 2e-59 S RDD family
NHPBOKKD_00303 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
NHPBOKKD_00304 2e-161 2.7.13.3 T GHKL domain
NHPBOKKD_00305 1.2e-126 lytR_2 T LytTr DNA-binding domain
NHPBOKKD_00306 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NHPBOKKD_00307 4.5e-203 natB CP ABC-2 family transporter protein
NHPBOKKD_00308 1.6e-174 yccK C Aldo keto reductase
NHPBOKKD_00309 6.6e-177 ycdA S Domain of unknown function (DUF5105)
NHPBOKKD_00310 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_00311 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_00312 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
NHPBOKKD_00313 5.5e-174 S response regulator aspartate phosphatase
NHPBOKKD_00314 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
NHPBOKKD_00315 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NHPBOKKD_00316 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
NHPBOKKD_00317 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHPBOKKD_00318 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHPBOKKD_00319 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPBOKKD_00320 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NHPBOKKD_00321 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NHPBOKKD_00322 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NHPBOKKD_00323 6.3e-137 terC P Protein of unknown function (DUF475)
NHPBOKKD_00324 0.0 yceG S Putative component of 'biosynthetic module'
NHPBOKKD_00325 2e-192 yceH P Belongs to the TelA family
NHPBOKKD_00326 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
NHPBOKKD_00327 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
NHPBOKKD_00328 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NHPBOKKD_00329 5.1e-229 proV 3.6.3.32 E glycine betaine
NHPBOKKD_00330 1.3e-127 opuAB P glycine betaine
NHPBOKKD_00331 5.3e-164 opuAC E glycine betaine
NHPBOKKD_00332 1.2e-219 amhX S amidohydrolase
NHPBOKKD_00333 1e-257 ycgA S Membrane
NHPBOKKD_00334 1.1e-98 ycgB
NHPBOKKD_00335 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
NHPBOKKD_00336 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NHPBOKKD_00337 6.5e-293 lctP C L-lactate permease
NHPBOKKD_00338 6.2e-269 mdr EGP Major facilitator Superfamily
NHPBOKKD_00339 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_00340 6.8e-113 ycgF E Lysine exporter protein LysE YggA
NHPBOKKD_00341 1.2e-151 yqcI S YqcI/YcgG family
NHPBOKKD_00342 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NHPBOKKD_00343 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NHPBOKKD_00344 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NHPBOKKD_00345 2.5e-109 tmrB S AAA domain
NHPBOKKD_00346 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NHPBOKKD_00347 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
NHPBOKKD_00348 2.2e-179 oxyR3 K LysR substrate binding domain
NHPBOKKD_00349 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NHPBOKKD_00350 2.9e-145 ycgL S Predicted nucleotidyltransferase
NHPBOKKD_00351 5.1e-170 ycgM E Proline dehydrogenase
NHPBOKKD_00352 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NHPBOKKD_00353 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPBOKKD_00354 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NHPBOKKD_00355 2.6e-147 ycgQ S membrane
NHPBOKKD_00356 1.2e-139 ycgR S permeases
NHPBOKKD_00357 5.7e-163 I alpha/beta hydrolase fold
NHPBOKKD_00358 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NHPBOKKD_00359 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NHPBOKKD_00360 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NHPBOKKD_00361 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NHPBOKKD_00362 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHPBOKKD_00363 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NHPBOKKD_00364 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
NHPBOKKD_00365 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NHPBOKKD_00366 5.5e-109 yciB M ErfK YbiS YcfS YnhG
NHPBOKKD_00367 1.4e-228 yciC S GTPases (G3E family)
NHPBOKKD_00368 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
NHPBOKKD_00369 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NHPBOKKD_00372 3.3e-77 yckC S membrane
NHPBOKKD_00373 3.5e-52 yckD S Protein of unknown function (DUF2680)
NHPBOKKD_00374 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPBOKKD_00375 3.4e-70 nin S Competence protein J (ComJ)
NHPBOKKD_00376 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
NHPBOKKD_00377 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
NHPBOKKD_00378 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NHPBOKKD_00379 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NHPBOKKD_00380 1.3e-63 hxlR K transcriptional
NHPBOKKD_00381 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_00382 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_00383 7.2e-115 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_00384 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NHPBOKKD_00385 5.7e-140 srfAD Q thioesterase
NHPBOKKD_00386 4.2e-228 EGP Major Facilitator Superfamily
NHPBOKKD_00387 4.9e-91 S YcxB-like protein
NHPBOKKD_00388 7.4e-164 ycxC EG EamA-like transporter family
NHPBOKKD_00389 4.4e-255 ycxD K GntR family transcriptional regulator
NHPBOKKD_00390 4.4e-75 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NHPBOKKD_00391 4.4e-115 yczE S membrane
NHPBOKKD_00392 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NHPBOKKD_00393 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NHPBOKKD_00394 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NHPBOKKD_00395 4.9e-162 bsdA K LysR substrate binding domain
NHPBOKKD_00396 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NHPBOKKD_00397 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NHPBOKKD_00398 4e-39 bsdD 4.1.1.61 S response to toxic substance
NHPBOKKD_00399 1.1e-83 yclD
NHPBOKKD_00400 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
NHPBOKKD_00401 1.5e-267 dtpT E amino acid peptide transporter
NHPBOKKD_00402 2.9e-310 yclG M Pectate lyase superfamily protein
NHPBOKKD_00404 6.8e-282 gerKA EG Spore germination protein
NHPBOKKD_00405 1.3e-232 gerKC S spore germination
NHPBOKKD_00406 9.9e-200 gerKB F Spore germination protein
NHPBOKKD_00407 3.9e-122 yclH P ABC transporter
NHPBOKKD_00408 1.7e-204 yclI V ABC transporter (permease) YclI
NHPBOKKD_00409 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_00410 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NHPBOKKD_00411 5.2e-71 S aspartate phosphatase
NHPBOKKD_00414 1.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
NHPBOKKD_00415 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_00416 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_00417 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NHPBOKKD_00418 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NHPBOKKD_00419 1.4e-251 ycnB EGP Major facilitator Superfamily
NHPBOKKD_00420 6.5e-154 ycnC K Transcriptional regulator
NHPBOKKD_00421 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NHPBOKKD_00422 1.6e-45 ycnE S Monooxygenase
NHPBOKKD_00423 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NHPBOKKD_00424 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPBOKKD_00425 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHPBOKKD_00426 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPBOKKD_00427 6.1e-149 glcU U Glucose uptake
NHPBOKKD_00428 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_00429 1.3e-100 ycnI S protein conserved in bacteria
NHPBOKKD_00430 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
NHPBOKKD_00431 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NHPBOKKD_00432 7.3e-56
NHPBOKKD_00433 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NHPBOKKD_00434 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NHPBOKKD_00435 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NHPBOKKD_00436 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NHPBOKKD_00437 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NHPBOKKD_00438 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NHPBOKKD_00439 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NHPBOKKD_00440 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NHPBOKKD_00442 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NHPBOKKD_00443 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
NHPBOKKD_00444 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NHPBOKKD_00445 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
NHPBOKKD_00446 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NHPBOKKD_00447 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NHPBOKKD_00448 1.2e-132 kipR K Transcriptional regulator
NHPBOKKD_00449 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
NHPBOKKD_00451 1.4e-49 yczJ S biosynthesis
NHPBOKKD_00452 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NHPBOKKD_00453 2.8e-176 ydhF S Oxidoreductase
NHPBOKKD_00454 0.0 mtlR K transcriptional regulator, MtlR
NHPBOKKD_00455 1.4e-294 ydaB IQ acyl-CoA ligase
NHPBOKKD_00456 1.1e-99 ydaC Q Methyltransferase domain
NHPBOKKD_00457 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_00458 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NHPBOKKD_00459 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHPBOKKD_00460 6.8e-77 ydaG 1.4.3.5 S general stress protein
NHPBOKKD_00461 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NHPBOKKD_00462 5.1e-47 ydzA EGP Major facilitator Superfamily
NHPBOKKD_00463 2.5e-74 lrpC K Transcriptional regulator
NHPBOKKD_00464 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHPBOKKD_00465 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
NHPBOKKD_00466 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
NHPBOKKD_00467 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
NHPBOKKD_00468 4.5e-233 ydaM M Glycosyl transferase family group 2
NHPBOKKD_00469 0.0 ydaN S Bacterial cellulose synthase subunit
NHPBOKKD_00470 0.0 ydaO E amino acid
NHPBOKKD_00471 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NHPBOKKD_00472 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NHPBOKKD_00473 9.4e-40
NHPBOKKD_00474 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NHPBOKKD_00476 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NHPBOKKD_00477 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NHPBOKKD_00479 8.9e-59 ydbB G Cupin domain
NHPBOKKD_00480 2.8e-63 ydbC S Domain of unknown function (DUF4937
NHPBOKKD_00481 3.2e-155 ydbD P Catalase
NHPBOKKD_00482 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NHPBOKKD_00483 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NHPBOKKD_00484 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
NHPBOKKD_00485 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPBOKKD_00486 4.4e-181 ydbI S AI-2E family transporter
NHPBOKKD_00487 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
NHPBOKKD_00488 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHPBOKKD_00489 2.7e-52 ydbL
NHPBOKKD_00490 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NHPBOKKD_00491 1.1e-18 S Fur-regulated basic protein B
NHPBOKKD_00492 2.2e-07 S Fur-regulated basic protein A
NHPBOKKD_00493 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHPBOKKD_00494 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NHPBOKKD_00495 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NHPBOKKD_00496 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NHPBOKKD_00497 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NHPBOKKD_00498 2.1e-82 ydbS S Bacterial PH domain
NHPBOKKD_00499 2.2e-263 ydbT S Membrane
NHPBOKKD_00500 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NHPBOKKD_00501 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NHPBOKKD_00502 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NHPBOKKD_00503 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHPBOKKD_00504 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NHPBOKKD_00505 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NHPBOKKD_00506 1.3e-143 rsbR T Positive regulator of sigma-B
NHPBOKKD_00507 5.2e-57 rsbS T antagonist
NHPBOKKD_00508 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NHPBOKKD_00509 7.1e-189 rsbU 3.1.3.3 KT phosphatase
NHPBOKKD_00510 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NHPBOKKD_00511 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NHPBOKKD_00512 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPBOKKD_00513 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NHPBOKKD_00517 1.5e-82 ydcG S EVE domain
NHPBOKKD_00518 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_00519 0.0 yhgF K COG2183 Transcriptional accessory protein
NHPBOKKD_00520 1.6e-84 ydcK S Belongs to the SprT family
NHPBOKKD_00528 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPBOKKD_00529 2.4e-71 lrpA K transcriptional
NHPBOKKD_00530 3.9e-78 lrpB K transcriptional
NHPBOKKD_00531 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
NHPBOKKD_00532 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
NHPBOKKD_00533 5e-227 ydeG EGP Major facilitator Superfamily
NHPBOKKD_00538 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NHPBOKKD_00539 8.7e-30 cspL K Cold shock
NHPBOKKD_00540 6.1e-79 carD K Transcription factor
NHPBOKKD_00541 4.6e-35 ydzE EG spore germination
NHPBOKKD_00542 1.1e-166 rhaS5 K AraC-like ligand binding domain
NHPBOKKD_00543 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NHPBOKKD_00544 2.5e-166 ydeE K AraC family transcriptional regulator
NHPBOKKD_00545 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPBOKKD_00546 3.4e-220 ydeG EGP Major facilitator superfamily
NHPBOKKD_00547 2.9e-47 ydeH
NHPBOKKD_00548 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NHPBOKKD_00549 4e-116
NHPBOKKD_00550 1.8e-153 ydeK EG -transporter
NHPBOKKD_00551 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPBOKKD_00552 4.2e-74 maoC I N-terminal half of MaoC dehydratase
NHPBOKKD_00553 8.6e-107 ydeN S Serine hydrolase
NHPBOKKD_00554 1.1e-58 K HxlR-like helix-turn-helix
NHPBOKKD_00555 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NHPBOKKD_00556 4.8e-69 ydeP K Transcriptional regulator
NHPBOKKD_00557 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
NHPBOKKD_00558 1.2e-195 ydeR EGP Major facilitator Superfamily
NHPBOKKD_00559 8.4e-105 ydeS K Transcriptional regulator
NHPBOKKD_00560 1.3e-57 arsR K transcriptional
NHPBOKKD_00561 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NHPBOKKD_00562 7.2e-149 ydfB J GNAT acetyltransferase
NHPBOKKD_00563 1e-162 ydfC EG EamA-like transporter family
NHPBOKKD_00564 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPBOKKD_00565 5.9e-117 ydfE S Flavin reductase like domain
NHPBOKKD_00566 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NHPBOKKD_00567 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHPBOKKD_00569 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
NHPBOKKD_00570 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPBOKKD_00571 0.0 ydfJ S drug exporters of the RND superfamily
NHPBOKKD_00572 1.9e-177 S Alpha/beta hydrolase family
NHPBOKKD_00573 5.9e-118 S Protein of unknown function (DUF554)
NHPBOKKD_00574 3.2e-147 K Bacterial transcription activator, effector binding domain
NHPBOKKD_00575 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHPBOKKD_00576 9.6e-112 ydfN C nitroreductase
NHPBOKKD_00577 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NHPBOKKD_00578 8.8e-63 mhqP S DoxX
NHPBOKKD_00579 1.3e-57 traF CO Thioredoxin
NHPBOKKD_00580 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NHPBOKKD_00581 6.3e-29
NHPBOKKD_00583 4.4e-118 ydfR S Protein of unknown function (DUF421)
NHPBOKKD_00584 5.2e-122 ydfS S Protein of unknown function (DUF421)
NHPBOKKD_00585 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
NHPBOKKD_00586 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
NHPBOKKD_00587 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NHPBOKKD_00588 1.5e-101 K Bacterial regulatory proteins, tetR family
NHPBOKKD_00589 1.9e-53 S DoxX-like family
NHPBOKKD_00590 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
NHPBOKKD_00591 4.2e-308 expZ S ABC transporter
NHPBOKKD_00592 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NHPBOKKD_00593 4.6e-91 dinB S DinB family
NHPBOKKD_00594 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_00595 0.0 ydgH S drug exporters of the RND superfamily
NHPBOKKD_00596 1e-113 drgA C nitroreductase
NHPBOKKD_00597 1.1e-69 ydgJ K Winged helix DNA-binding domain
NHPBOKKD_00598 2.5e-209 tcaB EGP Major facilitator Superfamily
NHPBOKKD_00599 1.2e-121 ydhB S membrane transporter protein
NHPBOKKD_00600 6.5e-122 ydhC K FCD
NHPBOKKD_00601 3.3e-244 ydhD M Glycosyl hydrolase
NHPBOKKD_00602 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NHPBOKKD_00603 1.9e-127
NHPBOKKD_00604 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NHPBOKKD_00605 4.6e-69 frataxin S Domain of unknown function (DU1801)
NHPBOKKD_00607 4.1e-86 K Acetyltransferase (GNAT) domain
NHPBOKKD_00608 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NHPBOKKD_00609 1.7e-99 ydhK M Protein of unknown function (DUF1541)
NHPBOKKD_00610 4.6e-200 pbuE EGP Major facilitator Superfamily
NHPBOKKD_00611 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NHPBOKKD_00612 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NHPBOKKD_00613 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHPBOKKD_00614 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPBOKKD_00615 3.9e-133 ydhQ K UTRA
NHPBOKKD_00616 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NHPBOKKD_00617 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHPBOKKD_00618 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NHPBOKKD_00619 8.7e-78 ydhU P Catalase
NHPBOKKD_00620 1.1e-16 ydhU P Manganese containing catalase
NHPBOKKD_00623 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00624 7.8e-08
NHPBOKKD_00626 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NHPBOKKD_00627 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NHPBOKKD_00628 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NHPBOKKD_00629 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NHPBOKKD_00630 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NHPBOKKD_00631 0.0 ydiF S ABC transporter
NHPBOKKD_00632 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NHPBOKKD_00633 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NHPBOKKD_00634 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NHPBOKKD_00635 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NHPBOKKD_00636 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NHPBOKKD_00637 7.9e-129 ydiL S CAAX protease self-immunity
NHPBOKKD_00638 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NHPBOKKD_00639 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NHPBOKKD_00641 6.4e-66 KL Phage plasmid primase P4 family
NHPBOKKD_00642 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NHPBOKKD_00643 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
NHPBOKKD_00645 1.2e-199 V AAA domain (dynein-related subfamily)
NHPBOKKD_00646 4.9e-257 J LlaJI restriction endonuclease
NHPBOKKD_00647 1.1e-08 ydjC S Abhydrolase domain containing 18
NHPBOKKD_00648 0.0 K NB-ARC domain
NHPBOKKD_00649 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
NHPBOKKD_00650 7.1e-256 gutA G MFS/sugar transport protein
NHPBOKKD_00651 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NHPBOKKD_00652 5.1e-114 pspA KT Phage shock protein A
NHPBOKKD_00653 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHPBOKKD_00654 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NHPBOKKD_00655 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
NHPBOKKD_00656 4.7e-196 S Ion transport 2 domain protein
NHPBOKKD_00657 2.7e-258 iolT EGP Major facilitator Superfamily
NHPBOKKD_00658 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NHPBOKKD_00659 4.5e-64 ydjM M Lytic transglycolase
NHPBOKKD_00660 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
NHPBOKKD_00662 1.4e-34 ydjO S Cold-inducible protein YdjO
NHPBOKKD_00663 9.5e-160 ydjP I Alpha/beta hydrolase family
NHPBOKKD_00664 2.4e-181 yeaA S Protein of unknown function (DUF4003)
NHPBOKKD_00665 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NHPBOKKD_00666 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NHPBOKKD_00667 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NHPBOKKD_00668 1.6e-177 yeaC S COG0714 MoxR-like ATPases
NHPBOKKD_00669 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NHPBOKKD_00670 0.0 yebA E COG1305 Transglutaminase-like enzymes
NHPBOKKD_00671 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NHPBOKKD_00672 6e-212 pbuG S permease
NHPBOKKD_00673 1.1e-118 yebC M Membrane
NHPBOKKD_00675 4e-93 yebE S UPF0316 protein
NHPBOKKD_00676 8e-28 yebG S NETI protein
NHPBOKKD_00677 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NHPBOKKD_00678 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NHPBOKKD_00679 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NHPBOKKD_00680 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NHPBOKKD_00681 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPBOKKD_00682 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPBOKKD_00683 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NHPBOKKD_00684 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NHPBOKKD_00685 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NHPBOKKD_00686 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NHPBOKKD_00687 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NHPBOKKD_00688 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
NHPBOKKD_00689 3.5e-73 K helix_turn_helix ASNC type
NHPBOKKD_00690 2.3e-232 yjeH E Amino acid permease
NHPBOKKD_00691 2.7e-27 S Protein of unknown function (DUF2892)
NHPBOKKD_00692 0.0 yerA 3.5.4.2 F adenine deaminase
NHPBOKKD_00693 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
NHPBOKKD_00694 4.8e-51 yerC S protein conserved in bacteria
NHPBOKKD_00695 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NHPBOKKD_00697 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NHPBOKKD_00698 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NHPBOKKD_00699 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NHPBOKKD_00700 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NHPBOKKD_00701 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
NHPBOKKD_00702 1.6e-123 sapB S MgtC SapB transporter
NHPBOKKD_00703 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPBOKKD_00704 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHPBOKKD_00705 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NHPBOKKD_00706 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NHPBOKKD_00707 4e-156 yerO K Transcriptional regulator
NHPBOKKD_00708 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NHPBOKKD_00709 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHPBOKKD_00710 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHPBOKKD_00711 3.2e-98 L Recombinase
NHPBOKKD_00712 3.2e-53 L Resolvase, N terminal domain
NHPBOKKD_00713 0.0 yeeA V Type II restriction enzyme, methylase subunits
NHPBOKKD_00714 0.0 yeeB L DEAD-like helicases superfamily
NHPBOKKD_00715 1.8e-212 pstS P T5orf172
NHPBOKKD_00717 6.2e-31 S Colicin immunity protein / pyocin immunity protein
NHPBOKKD_00718 5.5e-83 S Protein of unknown function, DUF600
NHPBOKKD_00719 0.0 L nucleic acid phosphodiester bond hydrolysis
NHPBOKKD_00720 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
NHPBOKKD_00721 5.5e-214 S Tetratricopeptide repeat
NHPBOKKD_00723 9.4e-127 yeeN K transcriptional regulatory protein
NHPBOKKD_00725 1.2e-103 dhaR3 K Transcriptional regulator
NHPBOKKD_00726 9.7e-82 yesE S SnoaL-like domain
NHPBOKKD_00727 2.2e-159 yesF GM NAD(P)H-binding
NHPBOKKD_00728 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NHPBOKKD_00729 1.5e-45 cotJB S CotJB protein
NHPBOKKD_00730 5.2e-104 cotJC P Spore Coat
NHPBOKKD_00731 4.2e-103 yesJ K Acetyltransferase (GNAT) family
NHPBOKKD_00733 4.4e-104 yesL S Protein of unknown function, DUF624
NHPBOKKD_00734 0.0 yesM 2.7.13.3 T Histidine kinase
NHPBOKKD_00735 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
NHPBOKKD_00736 5e-248 yesO G Bacterial extracellular solute-binding protein
NHPBOKKD_00737 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
NHPBOKKD_00738 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
NHPBOKKD_00739 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NHPBOKKD_00740 0.0 yesS K Transcriptional regulator
NHPBOKKD_00741 3.8e-133 E GDSL-like Lipase/Acylhydrolase
NHPBOKKD_00742 8.9e-132 yesU S Domain of unknown function (DUF1961)
NHPBOKKD_00743 1e-113 yesV S Protein of unknown function, DUF624
NHPBOKKD_00744 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NHPBOKKD_00745 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NHPBOKKD_00746 1.7e-108 yesY E GDSL-like Lipase/Acylhydrolase
NHPBOKKD_00747 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NHPBOKKD_00748 0.0 yetA
NHPBOKKD_00749 9.6e-291 lplA G Bacterial extracellular solute-binding protein
NHPBOKKD_00750 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NHPBOKKD_00751 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NHPBOKKD_00752 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NHPBOKKD_00753 6.1e-123 yetF S membrane
NHPBOKKD_00754 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NHPBOKKD_00755 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPBOKKD_00756 2.2e-34
NHPBOKKD_00757 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPBOKKD_00758 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPBOKKD_00759 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NHPBOKKD_00760 5.3e-105 yetJ S Belongs to the BI1 family
NHPBOKKD_00761 5.4e-159 yetK EG EamA-like transporter family
NHPBOKKD_00762 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_00763 7.8e-213 yetM CH FAD binding domain
NHPBOKKD_00764 3.6e-199 yetN S Protein of unknown function (DUF3900)
NHPBOKKD_00765 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NHPBOKKD_00766 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHPBOKKD_00767 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
NHPBOKKD_00768 1.9e-172 yfnG 4.2.1.45 M dehydratase
NHPBOKKD_00769 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
NHPBOKKD_00770 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NHPBOKKD_00771 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
NHPBOKKD_00772 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
NHPBOKKD_00773 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NHPBOKKD_00774 1.3e-241 yfnA E amino acid
NHPBOKKD_00775 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPBOKKD_00776 1.1e-113 yfmS NT chemotaxis protein
NHPBOKKD_00777 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHPBOKKD_00778 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
NHPBOKKD_00779 2.8e-70 yfmP K transcriptional
NHPBOKKD_00780 1.5e-209 yfmO EGP Major facilitator Superfamily
NHPBOKKD_00781 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHPBOKKD_00782 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NHPBOKKD_00783 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
NHPBOKKD_00784 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
NHPBOKKD_00785 7.7e-214 G Major Facilitator Superfamily
NHPBOKKD_00786 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
NHPBOKKD_00787 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NHPBOKKD_00788 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_00789 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_00790 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NHPBOKKD_00791 2.9e-24 S Protein of unknown function (DUF3212)
NHPBOKKD_00792 7.6e-58 yflT S Heat induced stress protein YflT
NHPBOKKD_00793 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NHPBOKKD_00794 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
NHPBOKKD_00795 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NHPBOKKD_00796 8.9e-119 citT T response regulator
NHPBOKKD_00797 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
NHPBOKKD_00799 8.5e-227 citM C Citrate transporter
NHPBOKKD_00800 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPBOKKD_00801 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NHPBOKKD_00802 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NHPBOKKD_00803 9e-124 yflK S protein conserved in bacteria
NHPBOKKD_00804 4e-18 yflJ S Protein of unknown function (DUF2639)
NHPBOKKD_00805 4.1e-19 yflI
NHPBOKKD_00806 2.4e-50 yflH S Protein of unknown function (DUF3243)
NHPBOKKD_00807 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NHPBOKKD_00808 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NHPBOKKD_00809 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHPBOKKD_00810 6e-67 yhdN S Domain of unknown function (DUF1992)
NHPBOKKD_00811 3.2e-256 agcS_1 E Sodium alanine symporter
NHPBOKKD_00812 1.6e-194 E Spore germination protein
NHPBOKKD_00814 5.1e-207 yfkR S spore germination
NHPBOKKD_00815 1.5e-283 yfkQ EG Spore germination protein
NHPBOKKD_00816 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPBOKKD_00817 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NHPBOKKD_00818 1.8e-133 treR K transcriptional
NHPBOKKD_00819 1.6e-125 yfkO C nitroreductase
NHPBOKKD_00820 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NHPBOKKD_00821 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
NHPBOKKD_00822 6.8e-207 ydiM EGP Major facilitator Superfamily
NHPBOKKD_00823 2.1e-29 yfkK S Belongs to the UPF0435 family
NHPBOKKD_00824 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHPBOKKD_00825 8.4e-51 yfkI S gas vesicle protein
NHPBOKKD_00826 9.7e-144 yihY S Belongs to the UPF0761 family
NHPBOKKD_00827 5e-08
NHPBOKKD_00828 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NHPBOKKD_00829 6.1e-183 cax P COG0387 Ca2 H antiporter
NHPBOKKD_00830 1.2e-146 yfkD S YfkD-like protein
NHPBOKKD_00831 6e-149 yfkC M Mechanosensitive ion channel
NHPBOKKD_00832 5.4e-222 yfkA S YfkB-like domain
NHPBOKKD_00833 1.1e-26 yfjT
NHPBOKKD_00834 2.6e-154 pdaA G deacetylase
NHPBOKKD_00835 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NHPBOKKD_00836 1.7e-184 corA P Mediates influx of magnesium ions
NHPBOKKD_00837 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NHPBOKKD_00838 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NHPBOKKD_00839 1.6e-39 S YfzA-like protein
NHPBOKKD_00840 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NHPBOKKD_00841 3.9e-86 yfjM S Psort location Cytoplasmic, score
NHPBOKKD_00842 3e-29 yfjL
NHPBOKKD_00843 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHPBOKKD_00844 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHPBOKKD_00845 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHPBOKKD_00846 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHPBOKKD_00847 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NHPBOKKD_00848 1.2e-25 sspH S Belongs to the SspH family
NHPBOKKD_00849 4e-56 yfjF S UPF0060 membrane protein
NHPBOKKD_00850 1.3e-80 S Family of unknown function (DUF5381)
NHPBOKKD_00851 1.8e-101 yfjD S Family of unknown function (DUF5381)
NHPBOKKD_00852 4.1e-144 yfjC
NHPBOKKD_00853 9.2e-191 yfjB
NHPBOKKD_00854 1.1e-44 yfjA S Belongs to the WXG100 family
NHPBOKKD_00855 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHPBOKKD_00856 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
NHPBOKKD_00857 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPBOKKD_00858 2.1e-310 yfiB3 V ABC transporter
NHPBOKKD_00859 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPBOKKD_00860 9.8e-65 mhqP S DoxX
NHPBOKKD_00861 5.7e-163 yfiE 1.13.11.2 S glyoxalase
NHPBOKKD_00862 1.5e-177 K AraC-like ligand binding domain
NHPBOKKD_00863 1.8e-262 iolT EGP Major facilitator Superfamily
NHPBOKKD_00864 8.4e-184 G Xylose isomerase
NHPBOKKD_00865 1.1e-233 S Oxidoreductase
NHPBOKKD_00867 1.1e-214 yxjM T Histidine kinase
NHPBOKKD_00868 3.2e-113 KT LuxR family transcriptional regulator
NHPBOKKD_00869 6.2e-171 V ABC transporter, ATP-binding protein
NHPBOKKD_00870 9.8e-214 V ABC-2 family transporter protein
NHPBOKKD_00871 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
NHPBOKKD_00872 8.3e-99 padR K transcriptional
NHPBOKKD_00873 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NHPBOKKD_00874 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NHPBOKKD_00875 2e-109 yfiR K Transcriptional regulator
NHPBOKKD_00876 5.1e-221 yfiS EGP Major facilitator Superfamily
NHPBOKKD_00877 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
NHPBOKKD_00878 8.7e-287 yfiU EGP Major facilitator Superfamily
NHPBOKKD_00879 3.1e-81 yfiV K transcriptional
NHPBOKKD_00880 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NHPBOKKD_00881 6.2e-182 yfiY P ABC transporter substrate-binding protein
NHPBOKKD_00882 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_00883 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_00884 1.8e-167 yfhB 5.3.3.17 S PhzF family
NHPBOKKD_00885 3.9e-107 yfhC C nitroreductase
NHPBOKKD_00886 2.1e-25 yfhD S YfhD-like protein
NHPBOKKD_00888 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
NHPBOKKD_00889 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NHPBOKKD_00890 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NHPBOKKD_00892 1.1e-209 yfhI EGP Major facilitator Superfamily
NHPBOKKD_00893 6.2e-20 sspK S reproduction
NHPBOKKD_00894 1.3e-44 yfhJ S WVELL protein
NHPBOKKD_00895 9.2e-92 batE T Bacterial SH3 domain homologues
NHPBOKKD_00896 3.5e-51 yfhL S SdpI/YhfL protein family
NHPBOKKD_00897 6.7e-172 yfhM S Alpha beta hydrolase
NHPBOKKD_00898 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPBOKKD_00899 0.0 yfhO S Bacterial membrane protein YfhO
NHPBOKKD_00900 5.5e-186 yfhP S membrane-bound metal-dependent
NHPBOKKD_00901 7.8e-212 mutY L A G-specific
NHPBOKKD_00902 6.9e-36 yfhS
NHPBOKKD_00903 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_00904 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NHPBOKKD_00905 1.5e-37 ygaB S YgaB-like protein
NHPBOKKD_00906 1.3e-104 ygaC J Belongs to the UPF0374 family
NHPBOKKD_00907 1.8e-301 ygaD V ABC transporter
NHPBOKKD_00908 8.7e-180 ygaE S Membrane
NHPBOKKD_00909 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NHPBOKKD_00910 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NHPBOKKD_00911 4e-80 perR P Belongs to the Fur family
NHPBOKKD_00912 1.5e-56 ygzB S UPF0295 protein
NHPBOKKD_00913 6.7e-167 ygxA S Nucleotidyltransferase-like
NHPBOKKD_00914 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_00919 7.8e-08
NHPBOKKD_00927 5.9e-08
NHPBOKKD_00931 2.7e-143 spo0M S COG4326 Sporulation control protein
NHPBOKKD_00932 3e-27
NHPBOKKD_00933 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NHPBOKKD_00934 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NHPBOKKD_00935 1.9e-266 ygaK C Berberine and berberine like
NHPBOKKD_00937 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NHPBOKKD_00938 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NHPBOKKD_00939 1.7e-171 ssuA M Sulfonate ABC transporter
NHPBOKKD_00940 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHPBOKKD_00941 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NHPBOKKD_00943 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NHPBOKKD_00944 4.1e-78 ygaO
NHPBOKKD_00945 4.4e-29 K Transcriptional regulator
NHPBOKKD_00947 7.9e-114 yhzB S B3/4 domain
NHPBOKKD_00948 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NHPBOKKD_00949 4.4e-177 yhbB S Putative amidase domain
NHPBOKKD_00950 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NHPBOKKD_00951 1.2e-109 yhbD K Protein of unknown function (DUF4004)
NHPBOKKD_00952 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NHPBOKKD_00953 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NHPBOKKD_00954 0.0 prkA T Ser protein kinase
NHPBOKKD_00955 2.5e-225 yhbH S Belongs to the UPF0229 family
NHPBOKKD_00956 2.2e-76 yhbI K DNA-binding transcription factor activity
NHPBOKKD_00957 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NHPBOKKD_00958 3.1e-271 yhcA EGP Major facilitator Superfamily
NHPBOKKD_00959 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NHPBOKKD_00960 2.8e-37 yhcC
NHPBOKKD_00961 7.8e-55
NHPBOKKD_00962 6.6e-60 yhcF K Transcriptional regulator
NHPBOKKD_00963 1.6e-123 yhcG V ABC transporter, ATP-binding protein
NHPBOKKD_00964 2.6e-166 yhcH V ABC transporter, ATP-binding protein
NHPBOKKD_00965 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHPBOKKD_00966 1e-30 cspB K Cold-shock protein
NHPBOKKD_00967 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
NHPBOKKD_00968 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NHPBOKKD_00969 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPBOKKD_00970 3.7e-44 yhcM
NHPBOKKD_00971 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPBOKKD_00972 1.1e-156 yhcP
NHPBOKKD_00973 5.2e-100 yhcQ M Spore coat protein
NHPBOKKD_00974 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NHPBOKKD_00975 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NHPBOKKD_00976 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHPBOKKD_00977 9.3e-68 yhcU S Family of unknown function (DUF5365)
NHPBOKKD_00978 8.3e-25 yhcV S COG0517 FOG CBS domain
NHPBOKKD_00979 9.1e-23 yhcV S COG0517 FOG CBS domain
NHPBOKKD_00980 4.6e-120 yhcW 5.4.2.6 S hydrolase
NHPBOKKD_00981 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHPBOKKD_00982 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHPBOKKD_00983 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NHPBOKKD_00984 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NHPBOKKD_00985 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NHPBOKKD_00986 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NHPBOKKD_00987 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NHPBOKKD_00988 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
NHPBOKKD_00989 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPBOKKD_00990 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
NHPBOKKD_00991 1.2e-38 yhdB S YhdB-like protein
NHPBOKKD_00992 4.8e-54 yhdC S Protein of unknown function (DUF3889)
NHPBOKKD_00993 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NHPBOKKD_00994 3.5e-76 nsrR K Transcriptional regulator
NHPBOKKD_00995 8.7e-239 ygxB M Conserved TM helix
NHPBOKKD_00996 2.1e-276 ycgB S Stage V sporulation protein R
NHPBOKKD_00997 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NHPBOKKD_00998 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NHPBOKKD_00999 3.8e-162 citR K Transcriptional regulator
NHPBOKKD_01000 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
NHPBOKKD_01001 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_01002 3.4e-250 yhdG E amino acid
NHPBOKKD_01003 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHPBOKKD_01004 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPBOKKD_01005 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPBOKKD_01006 8.1e-45 yhdK S Sigma-M inhibitor protein
NHPBOKKD_01007 6.6e-201 yhdL S Sigma factor regulator N-terminal
NHPBOKKD_01008 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_01009 1.5e-191 yhdN C Aldo keto reductase
NHPBOKKD_01010 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NHPBOKKD_01011 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NHPBOKKD_01012 4.1e-74 cueR K transcriptional
NHPBOKKD_01013 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
NHPBOKKD_01014 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NHPBOKKD_01015 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPBOKKD_01016 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NHPBOKKD_01017 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHPBOKKD_01019 6.6e-204 yhdY M Mechanosensitive ion channel
NHPBOKKD_01020 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NHPBOKKD_01021 1.7e-151 yheN G deacetylase
NHPBOKKD_01022 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NHPBOKKD_01023 2.2e-233 nhaC C Na H antiporter
NHPBOKKD_01024 3.4e-84 nhaX T Belongs to the universal stress protein A family
NHPBOKKD_01025 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPBOKKD_01026 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPBOKKD_01027 3.7e-111 yheG GM NAD(P)H-binding
NHPBOKKD_01028 6.3e-28 sspB S spore protein
NHPBOKKD_01029 1.3e-36 yheE S Family of unknown function (DUF5342)
NHPBOKKD_01030 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NHPBOKKD_01031 4.3e-216 yheC HJ YheC/D like ATP-grasp
NHPBOKKD_01032 6.7e-204 yheB S Belongs to the UPF0754 family
NHPBOKKD_01033 9.5e-48 yheA S Belongs to the UPF0342 family
NHPBOKKD_01034 3.1e-206 yhaZ L DNA alkylation repair enzyme
NHPBOKKD_01035 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NHPBOKKD_01036 7.1e-294 hemZ H coproporphyrinogen III oxidase
NHPBOKKD_01037 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NHPBOKKD_01038 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NHPBOKKD_01040 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
NHPBOKKD_01041 1.1e-26 S YhzD-like protein
NHPBOKKD_01042 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
NHPBOKKD_01043 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NHPBOKKD_01044 3.6e-227 yhaO L DNA repair exonuclease
NHPBOKKD_01045 0.0 yhaN L AAA domain
NHPBOKKD_01046 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NHPBOKKD_01047 1.6e-21 yhaL S Sporulation protein YhaL
NHPBOKKD_01048 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NHPBOKKD_01049 8.7e-90 yhaK S Putative zincin peptidase
NHPBOKKD_01050 1.3e-54 yhaI S Protein of unknown function (DUF1878)
NHPBOKKD_01051 1e-113 hpr K Negative regulator of protease production and sporulation
NHPBOKKD_01052 7e-39 yhaH S YtxH-like protein
NHPBOKKD_01053 3.6e-80 trpP S Tryptophan transporter TrpP
NHPBOKKD_01054 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NHPBOKKD_01055 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NHPBOKKD_01056 4.6e-137 ecsA V transporter (ATP-binding protein)
NHPBOKKD_01057 1.8e-215 ecsB U ABC transporter
NHPBOKKD_01058 4.8e-115 ecsC S EcsC protein family
NHPBOKKD_01059 5e-150 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHPBOKKD_01060 6e-57 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NHPBOKKD_01061 4.2e-248 yhfA C membrane
NHPBOKKD_01062 5.4e-10 1.15.1.2 C Rubrerythrin
NHPBOKKD_01063 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NHPBOKKD_01064 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHPBOKKD_01065 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NHPBOKKD_01066 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NHPBOKKD_01067 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NHPBOKKD_01068 1.4e-101 yhgD K Transcriptional regulator
NHPBOKKD_01069 1e-238 yhgE S YhgE Pip N-terminal domain protein
NHPBOKKD_01070 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHPBOKKD_01071 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
NHPBOKKD_01072 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NHPBOKKD_01073 1.7e-72 3.4.13.21 S ASCH
NHPBOKKD_01074 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NHPBOKKD_01075 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NHPBOKKD_01076 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
NHPBOKKD_01077 2.6e-112 yhfK GM NmrA-like family
NHPBOKKD_01078 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NHPBOKKD_01079 1.9e-65 yhfM
NHPBOKKD_01080 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
NHPBOKKD_01081 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NHPBOKKD_01082 9.2e-80 VY92_01935 K acetyltransferase
NHPBOKKD_01083 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NHPBOKKD_01084 4.3e-159 yfmC M Periplasmic binding protein
NHPBOKKD_01085 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NHPBOKKD_01086 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
NHPBOKKD_01087 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NHPBOKKD_01088 5e-91 bioY S BioY family
NHPBOKKD_01089 1.7e-182 hemAT NT chemotaxis protein
NHPBOKKD_01090 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NHPBOKKD_01091 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_01092 1.3e-32 yhzC S IDEAL
NHPBOKKD_01093 4.2e-109 comK K Competence transcription factor
NHPBOKKD_01094 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
NHPBOKKD_01095 7.8e-42 yhjA S Excalibur calcium-binding domain
NHPBOKKD_01096 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPBOKKD_01097 6.9e-27 yhjC S Protein of unknown function (DUF3311)
NHPBOKKD_01098 5e-60 yhjD
NHPBOKKD_01099 9.1e-110 yhjE S SNARE associated Golgi protein
NHPBOKKD_01100 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NHPBOKKD_01101 1.1e-286 yhjG CH FAD binding domain
NHPBOKKD_01102 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_01103 6.9e-215 glcP G Major Facilitator Superfamily
NHPBOKKD_01104 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NHPBOKKD_01105 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NHPBOKKD_01106 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NHPBOKKD_01107 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
NHPBOKKD_01108 3.8e-202 abrB S membrane
NHPBOKKD_01109 3.1e-215 EGP Transmembrane secretion effector
NHPBOKKD_01110 0.0 S Sugar transport-related sRNA regulator N-term
NHPBOKKD_01111 1.9e-34 yhjQ C COG1145 Ferredoxin
NHPBOKKD_01112 2.2e-78 yhjR S Rubrerythrin
NHPBOKKD_01113 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NHPBOKKD_01114 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NHPBOKKD_01115 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NHPBOKKD_01116 0.0 sbcC L COG0419 ATPase involved in DNA repair
NHPBOKKD_01117 6e-51 yisB V COG1403 Restriction endonuclease
NHPBOKKD_01118 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NHPBOKKD_01119 3e-66 gerPE S Spore germination protein GerPE
NHPBOKKD_01120 6.3e-24 gerPD S Spore germination protein
NHPBOKKD_01121 1.8e-54 gerPC S Spore germination protein
NHPBOKKD_01122 4e-34 gerPB S cell differentiation
NHPBOKKD_01123 1.9e-33 gerPA S Spore germination protein
NHPBOKKD_01124 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NHPBOKKD_01125 1.7e-176 cotH M Spore Coat
NHPBOKKD_01126 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NHPBOKKD_01127 3e-57 yisL S UPF0344 protein
NHPBOKKD_01128 0.0 wprA O Belongs to the peptidase S8 family
NHPBOKKD_01129 7.2e-106 yisN S Protein of unknown function (DUF2777)
NHPBOKKD_01130 0.0 asnO 6.3.5.4 E Asparagine synthase
NHPBOKKD_01131 2.1e-88 yizA S Damage-inducible protein DinB
NHPBOKKD_01132 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NHPBOKKD_01133 4e-243 yisQ V Mate efflux family protein
NHPBOKKD_01134 1.4e-161 yisR K Transcriptional regulator
NHPBOKKD_01135 2.4e-184 purR K helix_turn _helix lactose operon repressor
NHPBOKKD_01136 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NHPBOKKD_01137 1.3e-93 yisT S DinB family
NHPBOKKD_01138 6.4e-108 argO S Lysine exporter protein LysE YggA
NHPBOKKD_01139 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NHPBOKKD_01140 4e-36 mcbG S Pentapeptide repeats (9 copies)
NHPBOKKD_01141 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHPBOKKD_01142 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
NHPBOKKD_01143 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NHPBOKKD_01144 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NHPBOKKD_01145 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
NHPBOKKD_01146 1.9e-141 yitD 4.4.1.19 S synthase
NHPBOKKD_01147 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHPBOKKD_01148 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NHPBOKKD_01149 4e-229 yitG EGP Major facilitator Superfamily
NHPBOKKD_01150 1.8e-161 yitH K Acetyltransferase (GNAT) domain
NHPBOKKD_01151 2e-82 yjcF S Acetyltransferase (GNAT) domain
NHPBOKKD_01152 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NHPBOKKD_01153 8.6e-55 yajQ S Belongs to the UPF0234 family
NHPBOKKD_01154 4e-161 cvfB S protein conserved in bacteria
NHPBOKKD_01155 8.5e-94
NHPBOKKD_01156 2.8e-171
NHPBOKKD_01157 1.5e-97 S Sporulation delaying protein SdpA
NHPBOKKD_01158 1.5e-58 K Transcriptional regulator PadR-like family
NHPBOKKD_01159 2e-95
NHPBOKKD_01160 1.4e-44 yitR S Domain of unknown function (DUF3784)
NHPBOKKD_01161 2.2e-311 nprB 3.4.24.28 E Peptidase M4
NHPBOKKD_01162 8.4e-159 yitS S protein conserved in bacteria
NHPBOKKD_01163 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NHPBOKKD_01164 1.9e-72 ipi S Intracellular proteinase inhibitor
NHPBOKKD_01165 1.2e-17 S Protein of unknown function (DUF3813)
NHPBOKKD_01166 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NHPBOKKD_01167 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NHPBOKKD_01168 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NHPBOKKD_01169 1.5e-22 pilT S Proteolipid membrane potential modulator
NHPBOKKD_01170 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
NHPBOKKD_01171 1.7e-88 norB G Major Facilitator Superfamily
NHPBOKKD_01172 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NHPBOKKD_01173 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NHPBOKKD_01174 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NHPBOKKD_01175 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NHPBOKKD_01176 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHPBOKKD_01177 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NHPBOKKD_01178 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NHPBOKKD_01179 9.5e-28 yjzC S YjzC-like protein
NHPBOKKD_01180 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NHPBOKKD_01181 6.2e-142 yjaU I carboxylic ester hydrolase activity
NHPBOKKD_01182 7.3e-103 yjaV
NHPBOKKD_01183 1.1e-183 med S Transcriptional activator protein med
NHPBOKKD_01184 7.3e-26 comZ S ComZ
NHPBOKKD_01185 2.7e-22 yjzB
NHPBOKKD_01186 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NHPBOKKD_01187 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHPBOKKD_01188 7.8e-151 yjaZ O Zn-dependent protease
NHPBOKKD_01189 1.8e-184 appD P Belongs to the ABC transporter superfamily
NHPBOKKD_01190 6.5e-187 appF E Belongs to the ABC transporter superfamily
NHPBOKKD_01191 3.5e-48 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NHPBOKKD_01192 1.9e-190 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NHPBOKKD_01193 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPBOKKD_01194 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPBOKKD_01195 5e-147 yjbA S Belongs to the UPF0736 family
NHPBOKKD_01196 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NHPBOKKD_01197 0.0 oppA E ABC transporter substrate-binding protein
NHPBOKKD_01198 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPBOKKD_01199 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPBOKKD_01200 3e-198 oppD P Belongs to the ABC transporter superfamily
NHPBOKKD_01201 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NHPBOKKD_01202 8.6e-196 yjbB EGP Major Facilitator Superfamily
NHPBOKKD_01203 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPBOKKD_01204 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NHPBOKKD_01205 6e-112 yjbE P Integral membrane protein TerC family
NHPBOKKD_01206 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NHPBOKKD_01207 2.3e-223 yjbF S Competence protein
NHPBOKKD_01208 0.0 pepF E oligoendopeptidase F
NHPBOKKD_01209 1.8e-20
NHPBOKKD_01211 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NHPBOKKD_01212 3.7e-72 yjbI S Bacterial-like globin
NHPBOKKD_01213 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHPBOKKD_01214 2.4e-101 yjbK S protein conserved in bacteria
NHPBOKKD_01215 7.1e-62 yjbL S Belongs to the UPF0738 family
NHPBOKKD_01216 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NHPBOKKD_01217 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHPBOKKD_01218 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHPBOKKD_01219 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NHPBOKKD_01220 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NHPBOKKD_01221 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NHPBOKKD_01222 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NHPBOKKD_01223 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
NHPBOKKD_01224 3e-30 thiS H thiamine diphosphate biosynthetic process
NHPBOKKD_01225 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NHPBOKKD_01226 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHPBOKKD_01227 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NHPBOKKD_01228 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NHPBOKKD_01229 5.9e-54 yjbX S Spore coat protein
NHPBOKKD_01230 5.2e-83 cotZ S Spore coat protein
NHPBOKKD_01231 3.4e-96 cotY S Spore coat protein Z
NHPBOKKD_01232 6.4e-77 cotX S Spore Coat Protein X and V domain
NHPBOKKD_01233 3e-32 cotW
NHPBOKKD_01234 2.3e-55 cotV S Spore Coat Protein X and V domain
NHPBOKKD_01235 8.7e-57 yjcA S Protein of unknown function (DUF1360)
NHPBOKKD_01238 2.9e-38 spoVIF S Stage VI sporulation protein F
NHPBOKKD_01239 0.0 yjcD 3.6.4.12 L DNA helicase
NHPBOKKD_01240 1.7e-38
NHPBOKKD_01241 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPBOKKD_01242 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NHPBOKKD_01243 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NHPBOKKD_01244 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NHPBOKKD_01245 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NHPBOKKD_01246 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
NHPBOKKD_01247 1.1e-212 yjcL S Protein of unknown function (DUF819)
NHPBOKKD_01250 2.1e-190 S Putative amidase domain
NHPBOKKD_01251 2.6e-44 yjcN
NHPBOKKD_01254 8.5e-81 L Transposase
NHPBOKKD_01255 1.6e-72 yjcP
NHPBOKKD_01256 4.1e-49 S YjcQ protein
NHPBOKKD_01257 1.1e-92 yqaS L DNA packaging
NHPBOKKD_01258 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
NHPBOKKD_01259 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
NHPBOKKD_01261 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NHPBOKKD_01262 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NHPBOKKD_01263 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NHPBOKKD_01264 4.8e-51 yjdF S Protein of unknown function (DUF2992)
NHPBOKKD_01265 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NHPBOKKD_01267 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NHPBOKKD_01268 4.2e-29 S Domain of unknown function (DUF4177)
NHPBOKKD_01269 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
NHPBOKKD_01270 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NHPBOKKD_01272 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
NHPBOKKD_01273 5.5e-83 S Protein of unknown function (DUF2690)
NHPBOKKD_01274 3.6e-21 yjfB S Putative motility protein
NHPBOKKD_01275 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
NHPBOKKD_01276 1.2e-45 T PhoQ Sensor
NHPBOKKD_01277 8.9e-104 yjgB S Domain of unknown function (DUF4309)
NHPBOKKD_01278 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NHPBOKKD_01279 4.3e-95 yjgD S Protein of unknown function (DUF1641)
NHPBOKKD_01280 8.7e-07 S Domain of unknown function (DUF4352)
NHPBOKKD_01281 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NHPBOKKD_01283 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NHPBOKKD_01284 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NHPBOKKD_01285 8.2e-30
NHPBOKKD_01286 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NHPBOKKD_01287 1.9e-122 ybbM S transport system, permease component
NHPBOKKD_01288 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NHPBOKKD_01289 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
NHPBOKKD_01290 2.8e-93 yjlB S Cupin domain
NHPBOKKD_01291 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NHPBOKKD_01292 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NHPBOKKD_01293 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
NHPBOKKD_01294 5.8e-250 yjmB G symporter YjmB
NHPBOKKD_01295 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NHPBOKKD_01296 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NHPBOKKD_01297 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NHPBOKKD_01298 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_01299 3.7e-227 exuT G Sugar (and other) transporter
NHPBOKKD_01300 2.3e-184 exuR K transcriptional
NHPBOKKD_01301 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NHPBOKKD_01302 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NHPBOKKD_01303 4.3e-130 MA20_18170 S membrane transporter protein
NHPBOKKD_01304 3.3e-80 yjoA S DinB family
NHPBOKKD_01305 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NHPBOKKD_01306 2.1e-213 S response regulator aspartate phosphatase
NHPBOKKD_01308 6.3e-41 S YCII-related domain
NHPBOKKD_01309 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NHPBOKKD_01310 2.1e-61 yjqA S Bacterial PH domain
NHPBOKKD_01311 4.2e-112 yjqB S Pfam:DUF867
NHPBOKKD_01312 4.4e-160 ydbD P Catalase
NHPBOKKD_01313 1.6e-111 xkdA E IrrE N-terminal-like domain
NHPBOKKD_01314 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NHPBOKKD_01316 5.9e-157 xkdB K sequence-specific DNA binding
NHPBOKKD_01317 6.4e-119 xkdC L Bacterial dnaA protein
NHPBOKKD_01320 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NHPBOKKD_01321 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NHPBOKKD_01322 4.8e-140 xtmA L phage terminase small subunit
NHPBOKKD_01323 9.6e-255 xtmB S phage terminase, large subunit
NHPBOKKD_01324 5.4e-286 yqbA S portal protein
NHPBOKKD_01325 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NHPBOKKD_01326 5.8e-169 xkdG S Phage capsid family
NHPBOKKD_01327 5.5e-65 yqbG S Protein of unknown function (DUF3199)
NHPBOKKD_01328 8.7e-65 yqbH S Domain of unknown function (DUF3599)
NHPBOKKD_01329 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
NHPBOKKD_01330 1.9e-77 xkdJ
NHPBOKKD_01331 2.5e-256 xkdK S Phage tail sheath C-terminal domain
NHPBOKKD_01332 6.1e-76 xkdM S Phage tail tube protein
NHPBOKKD_01333 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
NHPBOKKD_01334 0.0 xkdO L Transglycosylase SLT domain
NHPBOKKD_01335 3.7e-122 xkdP S Lysin motif
NHPBOKKD_01336 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NHPBOKKD_01337 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NHPBOKKD_01338 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NHPBOKKD_01339 1.2e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NHPBOKKD_01340 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NHPBOKKD_01341 6.7e-41
NHPBOKKD_01342 0.0
NHPBOKKD_01343 2.6e-55 xkdW S XkdW protein
NHPBOKKD_01344 1.7e-23 xkdX
NHPBOKKD_01345 1.2e-154 xepA
NHPBOKKD_01346 2.8e-39 xhlA S Haemolysin XhlA
NHPBOKKD_01347 9.3e-40 xhlB S SPP1 phage holin
NHPBOKKD_01348 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPBOKKD_01349 6.7e-23 spoIISB S Stage II sporulation protein SB
NHPBOKKD_01350 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NHPBOKKD_01351 5.8e-175 pit P phosphate transporter
NHPBOKKD_01352 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NHPBOKKD_01353 9.4e-242 steT E amino acid
NHPBOKKD_01354 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NHPBOKKD_01356 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHPBOKKD_01357 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPBOKKD_01359 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHPBOKKD_01360 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NHPBOKKD_01361 7.9e-154 dppA E D-aminopeptidase
NHPBOKKD_01362 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPBOKKD_01363 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NHPBOKKD_01364 3.4e-191 dppD P Belongs to the ABC transporter superfamily
NHPBOKKD_01365 0.0 dppE E ABC transporter substrate-binding protein
NHPBOKKD_01367 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NHPBOKKD_01368 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NHPBOKKD_01369 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NHPBOKKD_01370 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
NHPBOKKD_01371 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
NHPBOKKD_01372 5.3e-161 ykgA E Amidinotransferase
NHPBOKKD_01373 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NHPBOKKD_01374 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NHPBOKKD_01375 1e-07
NHPBOKKD_01376 5.4e-130 ykjA S Protein of unknown function (DUF421)
NHPBOKKD_01377 1e-98 ykkA S Protein of unknown function (DUF664)
NHPBOKKD_01378 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHPBOKKD_01379 3.5e-55 ykkC P Multidrug resistance protein
NHPBOKKD_01380 2.2e-48 ykkD P Multidrug resistance protein
NHPBOKKD_01381 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NHPBOKKD_01382 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHPBOKKD_01383 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NHPBOKKD_01384 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NHPBOKKD_01385 3.9e-75 ohrR K COG1846 Transcriptional regulators
NHPBOKKD_01386 8.4e-72 ohrB O Organic hydroperoxide resistance protein
NHPBOKKD_01388 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NHPBOKKD_01389 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NHPBOKKD_01390 1.7e-176 isp O Belongs to the peptidase S8 family
NHPBOKKD_01391 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPBOKKD_01392 1.8e-136 ykoC P Cobalt transport protein
NHPBOKKD_01393 4.6e-311 P ABC transporter, ATP-binding protein
NHPBOKKD_01394 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
NHPBOKKD_01395 7.9e-111 ykoF S YKOF-related Family
NHPBOKKD_01396 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_01397 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
NHPBOKKD_01398 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
NHPBOKKD_01399 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
NHPBOKKD_01402 2.2e-222 mgtE P Acts as a magnesium transporter
NHPBOKKD_01403 1.4e-53 tnrA K transcriptional
NHPBOKKD_01404 5.9e-18
NHPBOKKD_01405 6.9e-26 ykoL
NHPBOKKD_01406 1.3e-81 mhqR K transcriptional
NHPBOKKD_01407 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NHPBOKKD_01408 3.7e-99 ykoP G polysaccharide deacetylase
NHPBOKKD_01409 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NHPBOKKD_01410 0.0 ykoS
NHPBOKKD_01411 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPBOKKD_01412 2.3e-262 ligD 6.5.1.1 L ATP-dependent DNA ligase
NHPBOKKD_01413 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NHPBOKKD_01414 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NHPBOKKD_01415 1.4e-116 ykoX S membrane-associated protein
NHPBOKKD_01416 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NHPBOKKD_01417 4.7e-129 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPBOKKD_01418 8.2e-117 rsgI S Anti-sigma factor N-terminus
NHPBOKKD_01419 1.9e-26 sspD S small acid-soluble spore protein
NHPBOKKD_01420 1.5e-124 ykrK S Domain of unknown function (DUF1836)
NHPBOKKD_01421 7e-156 htpX O Belongs to the peptidase M48B family
NHPBOKKD_01422 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NHPBOKKD_01423 1.2e-10 ydfR S Protein of unknown function (DUF421)
NHPBOKKD_01424 4.5e-22 ykzE
NHPBOKKD_01425 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NHPBOKKD_01426 0.0 kinE 2.7.13.3 T Histidine kinase
NHPBOKKD_01427 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NHPBOKKD_01429 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NHPBOKKD_01430 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NHPBOKKD_01431 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NHPBOKKD_01432 8e-232 mtnE 2.6.1.83 E Aminotransferase
NHPBOKKD_01433 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NHPBOKKD_01434 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NHPBOKKD_01435 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NHPBOKKD_01436 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NHPBOKKD_01437 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NHPBOKKD_01438 6.4e-09 S Spo0E like sporulation regulatory protein
NHPBOKKD_01439 1.4e-64 eag
NHPBOKKD_01440 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NHPBOKKD_01441 1.3e-75 ykvE K transcriptional
NHPBOKKD_01442 2.5e-125 motB N Flagellar motor protein
NHPBOKKD_01443 2.7e-138 motA N flagellar motor
NHPBOKKD_01444 0.0 clpE O Belongs to the ClpA ClpB family
NHPBOKKD_01445 8.7e-182 ykvI S membrane
NHPBOKKD_01446 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NHPBOKKD_01447 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NHPBOKKD_01448 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NHPBOKKD_01449 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NHPBOKKD_01450 2e-61 ykvN K Transcriptional regulator
NHPBOKKD_01451 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
NHPBOKKD_01452 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
NHPBOKKD_01453 1.2e-35 3.5.1.104 M LysM domain
NHPBOKKD_01454 8.5e-133 G Glycosyl hydrolases family 18
NHPBOKKD_01455 5.6e-46 ykvR S Protein of unknown function (DUF3219)
NHPBOKKD_01456 6e-25 ykvS S protein conserved in bacteria
NHPBOKKD_01457 2.8e-28
NHPBOKKD_01458 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
NHPBOKKD_01459 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPBOKKD_01460 4.9e-90 stoA CO thiol-disulfide
NHPBOKKD_01461 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NHPBOKKD_01462 3.8e-09
NHPBOKKD_01463 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NHPBOKKD_01465 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
NHPBOKKD_01467 4.5e-128 glcT K antiterminator
NHPBOKKD_01468 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPBOKKD_01469 2.1e-39 ptsH G phosphocarrier protein HPr
NHPBOKKD_01470 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NHPBOKKD_01471 7.2e-39 splA S Transcriptional regulator
NHPBOKKD_01472 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
NHPBOKKD_01473 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPBOKKD_01474 2e-264 mcpC NT chemotaxis protein
NHPBOKKD_01475 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NHPBOKKD_01476 8e-124 ykwD J protein with SCP PR1 domains
NHPBOKKD_01477 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NHPBOKKD_01478 0.0 pilS 2.7.13.3 T Histidine kinase
NHPBOKKD_01479 8e-224 patA 2.6.1.1 E Aminotransferase
NHPBOKKD_01480 2.2e-15
NHPBOKKD_01481 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NHPBOKKD_01482 1.7e-84 ykyB S YkyB-like protein
NHPBOKKD_01483 1.6e-238 ykuC EGP Major facilitator Superfamily
NHPBOKKD_01484 4.6e-88 ykuD S protein conserved in bacteria
NHPBOKKD_01485 9.4e-166 ykuE S Metallophosphoesterase
NHPBOKKD_01486 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_01487 0.0 3.2.1.132 M Putative peptidoglycan binding domain
NHPBOKKD_01488 1.7e-93 M Peptidoglycan-binding domain 1 protein
NHPBOKKD_01490 5.2e-234 ykuI T Diguanylate phosphodiesterase
NHPBOKKD_01491 3.9e-37 ykuJ S protein conserved in bacteria
NHPBOKKD_01492 4.4e-94 ykuK S Ribonuclease H-like
NHPBOKKD_01493 3.9e-27 ykzF S Antirepressor AbbA
NHPBOKKD_01494 1.6e-76 ykuL S CBS domain
NHPBOKKD_01495 3.5e-168 ccpC K Transcriptional regulator
NHPBOKKD_01496 5.7e-88 fld C Flavodoxin domain
NHPBOKKD_01497 3.2e-177 ykuO
NHPBOKKD_01498 3.2e-80 fld C Flavodoxin
NHPBOKKD_01499 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NHPBOKKD_01500 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NHPBOKKD_01501 9e-37 ykuS S Belongs to the UPF0180 family
NHPBOKKD_01502 8.8e-142 ykuT M Mechanosensitive ion channel
NHPBOKKD_01503 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NHPBOKKD_01504 4.4e-82 ykuV CO thiol-disulfide
NHPBOKKD_01505 5.8e-95 rok K Repressor of ComK
NHPBOKKD_01506 2.9e-147 yknT
NHPBOKKD_01507 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NHPBOKKD_01508 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NHPBOKKD_01509 8.1e-246 moeA 2.10.1.1 H molybdopterin
NHPBOKKD_01510 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NHPBOKKD_01511 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NHPBOKKD_01512 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NHPBOKKD_01513 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPBOKKD_01514 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NHPBOKKD_01515 1e-117 yknW S Yip1 domain
NHPBOKKD_01516 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NHPBOKKD_01517 2.5e-124 macB V ABC transporter, ATP-binding protein
NHPBOKKD_01518 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NHPBOKKD_01519 3.1e-136 fruR K Transcriptional regulator
NHPBOKKD_01520 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NHPBOKKD_01521 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NHPBOKKD_01522 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NHPBOKKD_01523 8.1e-39 ykoA
NHPBOKKD_01524 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NHPBOKKD_01525 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHPBOKKD_01526 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NHPBOKKD_01527 1.1e-12 S Uncharacterized protein YkpC
NHPBOKKD_01528 7.7e-183 mreB D Rod-share determining protein MreBH
NHPBOKKD_01529 1.5e-43 abrB K of stationary sporulation gene expression
NHPBOKKD_01530 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NHPBOKKD_01531 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NHPBOKKD_01532 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NHPBOKKD_01533 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NHPBOKKD_01534 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHPBOKKD_01535 8.2e-31 ykzG S Belongs to the UPF0356 family
NHPBOKKD_01536 1.4e-147 ykrA S hydrolases of the HAD superfamily
NHPBOKKD_01537 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHPBOKKD_01539 2e-115 recN L Putative cell-wall binding lipoprotein
NHPBOKKD_01540 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHPBOKKD_01541 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHPBOKKD_01542 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHPBOKKD_01543 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHPBOKKD_01544 6.6e-60 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NHPBOKKD_01545 3.5e-277 speA 4.1.1.19 E Arginine
NHPBOKKD_01546 1.6e-42 yktA S Belongs to the UPF0223 family
NHPBOKKD_01547 7.1e-118 yktB S Belongs to the UPF0637 family
NHPBOKKD_01548 7.1e-26 ykzI
NHPBOKKD_01549 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
NHPBOKKD_01550 6.9e-78 ykzC S Acetyltransferase (GNAT) family
NHPBOKKD_01551 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NHPBOKKD_01552 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NHPBOKKD_01553 0.0 ylaA
NHPBOKKD_01554 2.7e-42 ylaB
NHPBOKKD_01555 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_01556 1.2e-11 sigC S Putative zinc-finger
NHPBOKKD_01557 1.8e-38 ylaE
NHPBOKKD_01558 8.2e-22 S Family of unknown function (DUF5325)
NHPBOKKD_01559 0.0 typA T GTP-binding protein TypA
NHPBOKKD_01560 4.2e-47 ylaH S YlaH-like protein
NHPBOKKD_01561 2.5e-32 ylaI S protein conserved in bacteria
NHPBOKKD_01562 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPBOKKD_01563 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NHPBOKKD_01564 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NHPBOKKD_01565 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NHPBOKKD_01566 8.7e-44 ylaN S Belongs to the UPF0358 family
NHPBOKKD_01567 4.5e-214 ftsW D Belongs to the SEDS family
NHPBOKKD_01568 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NHPBOKKD_01569 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NHPBOKKD_01570 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NHPBOKKD_01571 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NHPBOKKD_01572 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHPBOKKD_01573 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NHPBOKKD_01574 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NHPBOKKD_01575 3e-167 ctaG S cytochrome c oxidase
NHPBOKKD_01576 7e-62 ylbA S YugN-like family
NHPBOKKD_01577 2.6e-74 ylbB T COG0517 FOG CBS domain
NHPBOKKD_01578 3e-201 ylbC S protein with SCP PR1 domains
NHPBOKKD_01579 4.1e-63 ylbD S Putative coat protein
NHPBOKKD_01580 6.7e-37 ylbE S YlbE-like protein
NHPBOKKD_01581 1.8e-75 ylbF S Belongs to the UPF0342 family
NHPBOKKD_01582 7.5e-39 ylbG S UPF0298 protein
NHPBOKKD_01583 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
NHPBOKKD_01584 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NHPBOKKD_01585 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
NHPBOKKD_01586 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NHPBOKKD_01587 6.8e-187 ylbL T Belongs to the peptidase S16 family
NHPBOKKD_01588 2.8e-235 ylbM S Belongs to the UPF0348 family
NHPBOKKD_01590 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
NHPBOKKD_01591 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NHPBOKKD_01592 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NHPBOKKD_01593 4e-89 ylbP K n-acetyltransferase
NHPBOKKD_01594 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NHPBOKKD_01595 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NHPBOKKD_01596 2.9e-78 mraZ K Belongs to the MraZ family
NHPBOKKD_01597 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NHPBOKKD_01598 3.7e-44 ftsL D Essential cell division protein
NHPBOKKD_01599 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NHPBOKKD_01600 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NHPBOKKD_01601 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NHPBOKKD_01602 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NHPBOKKD_01603 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NHPBOKKD_01604 5.7e-186 spoVE D Belongs to the SEDS family
NHPBOKKD_01605 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NHPBOKKD_01606 5.3e-167 murB 1.3.1.98 M cell wall formation
NHPBOKKD_01607 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NHPBOKKD_01608 2.4e-103 ylxW S protein conserved in bacteria
NHPBOKKD_01609 1e-102 ylxX S protein conserved in bacteria
NHPBOKKD_01610 6.2e-58 sbp S small basic protein
NHPBOKKD_01611 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NHPBOKKD_01612 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NHPBOKKD_01613 0.0 bpr O COG1404 Subtilisin-like serine proteases
NHPBOKKD_01614 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NHPBOKKD_01615 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPBOKKD_01616 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPBOKKD_01617 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NHPBOKKD_01618 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
NHPBOKKD_01619 2.4e-37 ylmC S sporulation protein
NHPBOKKD_01620 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NHPBOKKD_01621 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NHPBOKKD_01622 3.3e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NHPBOKKD_01623 1.3e-39 yggT S membrane
NHPBOKKD_01624 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NHPBOKKD_01625 2.6e-67 divIVA D Cell division initiation protein
NHPBOKKD_01626 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NHPBOKKD_01627 1.3e-63 dksA T COG1734 DnaK suppressor protein
NHPBOKKD_01628 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NHPBOKKD_01629 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NHPBOKKD_01630 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NHPBOKKD_01631 9e-232 pyrP F Xanthine uracil
NHPBOKKD_01632 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NHPBOKKD_01633 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NHPBOKKD_01634 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NHPBOKKD_01635 0.0 carB 6.3.5.5 F Belongs to the CarB family
NHPBOKKD_01636 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NHPBOKKD_01637 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NHPBOKKD_01638 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NHPBOKKD_01639 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NHPBOKKD_01641 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NHPBOKKD_01642 1.1e-179 cysP P phosphate transporter
NHPBOKKD_01643 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NHPBOKKD_01644 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NHPBOKKD_01645 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NHPBOKKD_01646 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NHPBOKKD_01647 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NHPBOKKD_01648 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NHPBOKKD_01649 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NHPBOKKD_01650 2.4e-156 yloC S stress-induced protein
NHPBOKKD_01651 1.5e-40 ylzA S Belongs to the UPF0296 family
NHPBOKKD_01652 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NHPBOKKD_01653 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NHPBOKKD_01654 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NHPBOKKD_01655 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NHPBOKKD_01656 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NHPBOKKD_01657 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NHPBOKKD_01658 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NHPBOKKD_01659 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NHPBOKKD_01660 2.4e-141 stp 3.1.3.16 T phosphatase
NHPBOKKD_01661 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NHPBOKKD_01662 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NHPBOKKD_01663 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NHPBOKKD_01664 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NHPBOKKD_01665 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NHPBOKKD_01666 5.5e-59 asp S protein conserved in bacteria
NHPBOKKD_01667 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
NHPBOKKD_01668 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NHPBOKKD_01669 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NHPBOKKD_01670 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NHPBOKKD_01671 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NHPBOKKD_01672 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NHPBOKKD_01673 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NHPBOKKD_01674 6.1e-129 IQ reductase
NHPBOKKD_01675 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NHPBOKKD_01676 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NHPBOKKD_01677 0.0 smc D Required for chromosome condensation and partitioning
NHPBOKKD_01678 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NHPBOKKD_01679 2.9e-87
NHPBOKKD_01680 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NHPBOKKD_01681 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NHPBOKKD_01682 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NHPBOKKD_01683 1.2e-36 ylqC S Belongs to the UPF0109 family
NHPBOKKD_01684 1.3e-61 ylqD S YlqD protein
NHPBOKKD_01685 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NHPBOKKD_01686 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NHPBOKKD_01687 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NHPBOKKD_01688 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NHPBOKKD_01689 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHPBOKKD_01690 8.5e-291 ylqG
NHPBOKKD_01691 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NHPBOKKD_01692 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NHPBOKKD_01693 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NHPBOKKD_01694 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NHPBOKKD_01695 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NHPBOKKD_01696 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NHPBOKKD_01697 2.5e-169 xerC L tyrosine recombinase XerC
NHPBOKKD_01698 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NHPBOKKD_01699 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NHPBOKKD_01700 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NHPBOKKD_01701 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NHPBOKKD_01702 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
NHPBOKKD_01703 1.9e-31 fliE N Flagellar hook-basal body
NHPBOKKD_01704 2.4e-255 fliF N The M ring may be actively involved in energy transduction
NHPBOKKD_01705 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NHPBOKKD_01706 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NHPBOKKD_01707 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NHPBOKKD_01708 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NHPBOKKD_01709 7.7e-37 ylxF S MgtE intracellular N domain
NHPBOKKD_01710 1.2e-221 fliK N Flagellar hook-length control protein
NHPBOKKD_01711 1.7e-72 flgD N Flagellar basal body rod modification protein
NHPBOKKD_01712 8.2e-140 flgG N Flagellar basal body rod
NHPBOKKD_01713 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NHPBOKKD_01714 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NHPBOKKD_01715 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NHPBOKKD_01716 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NHPBOKKD_01717 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
NHPBOKKD_01718 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NHPBOKKD_01719 2.2e-36 fliQ N Role in flagellar biosynthesis
NHPBOKKD_01720 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NHPBOKKD_01721 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NHPBOKKD_01722 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NHPBOKKD_01723 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
NHPBOKKD_01724 7.5e-158 flhG D Belongs to the ParA family
NHPBOKKD_01725 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NHPBOKKD_01726 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NHPBOKKD_01727 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NHPBOKKD_01728 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NHPBOKKD_01729 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NHPBOKKD_01730 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPBOKKD_01731 4.3e-78 ylxL
NHPBOKKD_01732 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NHPBOKKD_01733 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NHPBOKKD_01734 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NHPBOKKD_01735 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NHPBOKKD_01736 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NHPBOKKD_01737 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NHPBOKKD_01738 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NHPBOKKD_01739 7.7e-233 rasP M zinc metalloprotease
NHPBOKKD_01740 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NHPBOKKD_01741 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NHPBOKKD_01742 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NHPBOKKD_01743 7.3e-203 nusA K Participates in both transcription termination and antitermination
NHPBOKKD_01744 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NHPBOKKD_01745 3.1e-47 ylxQ J ribosomal protein
NHPBOKKD_01746 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NHPBOKKD_01747 3e-44 ylxP S protein conserved in bacteria
NHPBOKKD_01748 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NHPBOKKD_01749 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NHPBOKKD_01750 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NHPBOKKD_01751 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NHPBOKKD_01752 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NHPBOKKD_01753 3.2e-172 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NHPBOKKD_01754 4.4e-233 pepR S Belongs to the peptidase M16 family
NHPBOKKD_01755 2.6e-42 ymxH S YlmC YmxH family
NHPBOKKD_01756 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NHPBOKKD_01757 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NHPBOKKD_01758 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NHPBOKKD_01759 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NHPBOKKD_01760 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NHPBOKKD_01761 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NHPBOKKD_01762 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NHPBOKKD_01763 4.4e-32 S YlzJ-like protein
NHPBOKKD_01764 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NHPBOKKD_01765 1.4e-133 ymfC K Transcriptional regulator
NHPBOKKD_01766 3.4e-206 ymfD EGP Major facilitator Superfamily
NHPBOKKD_01767 2.6e-236 ymfF S Peptidase M16
NHPBOKKD_01768 1.4e-242 ymfH S zinc protease
NHPBOKKD_01769 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NHPBOKKD_01770 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NHPBOKKD_01771 2.4e-76 ymfK S Protein of unknown function (DUF3388)
NHPBOKKD_01772 3.1e-53 ymfK S Protein of unknown function (DUF3388)
NHPBOKKD_01773 1.9e-124 ymfM S protein conserved in bacteria
NHPBOKKD_01774 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NHPBOKKD_01775 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
NHPBOKKD_01776 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NHPBOKKD_01777 1e-215 pbpX V Beta-lactamase
NHPBOKKD_01778 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NHPBOKKD_01779 1.9e-152 ymdB S protein conserved in bacteria
NHPBOKKD_01780 1.2e-36 spoVS S Stage V sporulation protein S
NHPBOKKD_01781 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NHPBOKKD_01782 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NHPBOKKD_01783 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NHPBOKKD_01784 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NHPBOKKD_01785 2.2e-88 cotE S Spore coat protein
NHPBOKKD_01786 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NHPBOKKD_01787 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NHPBOKKD_01788 2.3e-70 S Regulatory protein YrvL
NHPBOKKD_01790 1.2e-97 ymcC S Membrane
NHPBOKKD_01791 4.4e-109 pksA K Transcriptional regulator
NHPBOKKD_01792 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
NHPBOKKD_01793 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NHPBOKKD_01795 2.4e-186 pksD Q Acyl transferase domain
NHPBOKKD_01796 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NHPBOKKD_01797 1.4e-37 acpK IQ Phosphopantetheine attachment site
NHPBOKKD_01798 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NHPBOKKD_01799 1.3e-245 pksG 2.3.3.10 I synthase
NHPBOKKD_01800 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
NHPBOKKD_01801 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
NHPBOKKD_01802 0.0 rhiB IQ polyketide synthase
NHPBOKKD_01803 0.0 pfaA Q Polyketide synthase of type I
NHPBOKKD_01804 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
NHPBOKKD_01805 0.0 dhbF IQ polyketide synthase
NHPBOKKD_01806 0.0 dhbF IQ polyketide synthase
NHPBOKKD_01807 0.0 pks13 HQ Beta-ketoacyl synthase
NHPBOKKD_01808 2.5e-233 cypA C Cytochrome P450
NHPBOKKD_01809 1.2e-61 ymzB
NHPBOKKD_01810 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
NHPBOKKD_01811 4.6e-252 aprX O Belongs to the peptidase S8 family
NHPBOKKD_01812 2.1e-126 ymaC S Replication protein
NHPBOKKD_01813 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
NHPBOKKD_01814 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NHPBOKKD_01815 4.9e-51 ebrA P Small Multidrug Resistance protein
NHPBOKKD_01817 2.1e-46 ymaF S YmaF family
NHPBOKKD_01818 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NHPBOKKD_01819 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NHPBOKKD_01820 6.3e-23
NHPBOKKD_01821 4.5e-22 ymzA
NHPBOKKD_01822 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NHPBOKKD_01823 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPBOKKD_01824 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPBOKKD_01825 2e-109 ymaB
NHPBOKKD_01826 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPBOKKD_01827 1.7e-176 spoVK O stage V sporulation protein K
NHPBOKKD_01828 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NHPBOKKD_01829 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NHPBOKKD_01830 1.1e-68 glnR K transcriptional
NHPBOKKD_01831 7e-261 glnA 6.3.1.2 E glutamine synthetase
NHPBOKKD_01832 5e-10
NHPBOKKD_01833 2.5e-32
NHPBOKKD_01834 5.8e-39
NHPBOKKD_01835 6.8e-80 G regulation of fungal-type cell wall biogenesis
NHPBOKKD_01836 4.9e-145 ynaC
NHPBOKKD_01837 2e-99 ynaD J Acetyltransferase (GNAT) domain
NHPBOKKD_01838 1.9e-123 ynaE S Domain of unknown function (DUF3885)
NHPBOKKD_01839 6.4e-60 ynaF
NHPBOKKD_01842 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NHPBOKKD_01843 2.7e-255 xynT G MFS/sugar transport protein
NHPBOKKD_01844 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NHPBOKKD_01845 1e-215 xylR GK ROK family
NHPBOKKD_01846 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NHPBOKKD_01847 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NHPBOKKD_01848 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
NHPBOKKD_01849 3.5e-247 iolT EGP Major facilitator Superfamily
NHPBOKKD_01850 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NHPBOKKD_01851 6.3e-84 yncE S Protein of unknown function (DUF2691)
NHPBOKKD_01852 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NHPBOKKD_01853 5.2e-15
NHPBOKKD_01856 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHPBOKKD_01858 1.3e-134 S Domain of unknown function, YrpD
NHPBOKKD_01861 7.9e-25 tatA U protein secretion
NHPBOKKD_01862 1.8e-71
NHPBOKKD_01863 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NHPBOKKD_01866 5.7e-286 gerAA EG Spore germination protein
NHPBOKKD_01867 4.5e-197 gerAB U Spore germination
NHPBOKKD_01868 4.2e-220 gerLC S Spore germination protein
NHPBOKKD_01869 7.7e-154 yndG S DoxX-like family
NHPBOKKD_01870 2.6e-117 yndH S Domain of unknown function (DUF4166)
NHPBOKKD_01871 0.0 yndJ S YndJ-like protein
NHPBOKKD_01873 8.6e-139 yndL S Replication protein
NHPBOKKD_01874 5.8e-74 yndM S Protein of unknown function (DUF2512)
NHPBOKKD_01875 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NHPBOKKD_01877 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NHPBOKKD_01878 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NHPBOKKD_01879 9.2e-113 yneB L resolvase
NHPBOKKD_01880 1.3e-32 ynzC S UPF0291 protein
NHPBOKKD_01881 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NHPBOKKD_01882 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NHPBOKKD_01883 1.8e-28 yneF S UPF0154 protein
NHPBOKKD_01884 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NHPBOKKD_01885 7.1e-127 ccdA O cytochrome c biogenesis protein
NHPBOKKD_01886 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NHPBOKKD_01887 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NHPBOKKD_01888 4.2e-74 yneK S Protein of unknown function (DUF2621)
NHPBOKKD_01889 4.1e-65 hspX O Spore coat protein
NHPBOKKD_01890 3.9e-19 sspP S Belongs to the SspP family
NHPBOKKD_01891 2.2e-14 sspO S Belongs to the SspO family
NHPBOKKD_01892 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NHPBOKKD_01893 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NHPBOKKD_01895 3.1e-08 sspN S Small acid-soluble spore protein N family
NHPBOKKD_01896 3.9e-35 tlp S Belongs to the Tlp family
NHPBOKKD_01897 1.2e-73 yneP S Thioesterase-like superfamily
NHPBOKKD_01898 1.3e-53 yneQ
NHPBOKKD_01899 4.1e-49 yneR S Belongs to the HesB IscA family
NHPBOKKD_01900 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NHPBOKKD_01901 6.6e-69 yccU S CoA-binding protein
NHPBOKKD_01902 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHPBOKKD_01903 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NHPBOKKD_01904 5.9e-43 ynfC
NHPBOKKD_01905 8.2e-252 agcS E Sodium alanine symporter
NHPBOKKD_01906 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NHPBOKKD_01908 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NHPBOKKD_01909 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NHPBOKKD_01910 2.4e-80 yngA S membrane
NHPBOKKD_01911 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHPBOKKD_01912 5.5e-104 yngC S membrane-associated protein
NHPBOKKD_01913 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
NHPBOKKD_01914 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHPBOKKD_01915 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NHPBOKKD_01916 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NHPBOKKD_01917 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NHPBOKKD_01918 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NHPBOKKD_01919 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHPBOKKD_01920 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NHPBOKKD_01921 1.8e-31 S Family of unknown function (DUF5367)
NHPBOKKD_01923 1.3e-306 yngK T Glycosyl hydrolase-like 10
NHPBOKKD_01924 2.8e-64 yngL S Protein of unknown function (DUF1360)
NHPBOKKD_01925 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NHPBOKKD_01926 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_01927 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_01928 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_01929 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_01930 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_01931 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_01932 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NHPBOKKD_01933 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
NHPBOKKD_01934 2.3e-246 yoeA V MATE efflux family protein
NHPBOKKD_01935 7e-98 yoeB S IseA DL-endopeptidase inhibitor
NHPBOKKD_01937 2.2e-96 L Integrase
NHPBOKKD_01938 3e-34 yoeD G Helix-turn-helix domain
NHPBOKKD_01939 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NHPBOKKD_01940 2.5e-158 gltR1 K Transcriptional regulator
NHPBOKKD_01941 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NHPBOKKD_01942 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NHPBOKKD_01943 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NHPBOKKD_01944 7.8e-155 gltC K Transcriptional regulator
NHPBOKKD_01945 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NHPBOKKD_01946 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHPBOKKD_01947 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NHPBOKKD_01948 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_01949 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
NHPBOKKD_01950 3.1e-144 yoxB
NHPBOKKD_01951 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NHPBOKKD_01952 6.2e-235 yoaB EGP Major facilitator Superfamily
NHPBOKKD_01953 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NHPBOKKD_01954 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPBOKKD_01955 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHPBOKKD_01956 1.9e-33 yoaF
NHPBOKKD_01957 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
NHPBOKKD_01958 7e-14
NHPBOKKD_01959 1.5e-38 S Protein of unknown function (DUF4025)
NHPBOKKD_01960 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
NHPBOKKD_01961 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NHPBOKKD_01962 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NHPBOKKD_01963 2.3e-111 yoaK S Membrane
NHPBOKKD_01964 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NHPBOKKD_01965 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
NHPBOKKD_01967 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
NHPBOKKD_01969 1.5e-146 yoaP 3.1.3.18 K YoaP-like
NHPBOKKD_01970 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
NHPBOKKD_01971 4.1e-89
NHPBOKKD_01972 2.4e-172 yoaR V vancomycin resistance protein
NHPBOKKD_01973 4.3e-75 yoaS S Protein of unknown function (DUF2975)
NHPBOKKD_01974 4.2e-37 yozG K Transcriptional regulator
NHPBOKKD_01975 1.1e-149 yoaT S Protein of unknown function (DUF817)
NHPBOKKD_01976 8.6e-159 yoaU K LysR substrate binding domain
NHPBOKKD_01977 6e-160 yijE EG EamA-like transporter family
NHPBOKKD_01978 3.7e-78 yoaW
NHPBOKKD_01979 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NHPBOKKD_01980 2.3e-170 bla 3.5.2.6 V beta-lactamase
NHPBOKKD_01984 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NHPBOKKD_01985 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NHPBOKKD_01986 1.4e-37 S TM2 domain
NHPBOKKD_01987 5.7e-58 K Helix-turn-helix
NHPBOKKD_01989 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
NHPBOKKD_01990 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
NHPBOKKD_01991 1.8e-178 yobF
NHPBOKKD_01996 1.7e-207 S aspartate phosphatase
NHPBOKKD_01998 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHPBOKKD_01999 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHPBOKKD_02000 2.6e-38 S YolD-like protein
NHPBOKKD_02001 1.2e-49
NHPBOKKD_02002 0.0 K Psort location Cytoplasmic, score
NHPBOKKD_02003 2.7e-157 yobJ
NHPBOKKD_02004 3e-86 S SMI1-KNR4 cell-wall
NHPBOKKD_02005 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NHPBOKKD_02006 7.9e-105 yokH G SMI1 / KNR4 family
NHPBOKKD_02007 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NHPBOKKD_02008 0.0 yobO M Pectate lyase superfamily protein
NHPBOKKD_02009 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NHPBOKKD_02010 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
NHPBOKKD_02011 2.5e-143 yobR 2.3.1.1 J FR47-like protein
NHPBOKKD_02012 3e-99 yobS K Transcriptional regulator
NHPBOKKD_02013 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPBOKKD_02014 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
NHPBOKKD_02015 9e-178 yobV K WYL domain
NHPBOKKD_02016 2.5e-95 yobW
NHPBOKKD_02017 1e-51 czrA K transcriptional
NHPBOKKD_02018 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHPBOKKD_02019 1.5e-92 yozB S membrane
NHPBOKKD_02020 2.2e-145
NHPBOKKD_02021 1.9e-94 yocC
NHPBOKKD_02022 6.9e-189 yocD 3.4.17.13 V peptidase S66
NHPBOKKD_02023 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NHPBOKKD_02024 3.2e-198 desK 2.7.13.3 T Histidine kinase
NHPBOKKD_02025 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPBOKKD_02026 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
NHPBOKKD_02027 0.0 recQ 3.6.4.12 L DNA helicase
NHPBOKKD_02028 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHPBOKKD_02029 3.3e-83 dksA T general stress protein
NHPBOKKD_02030 6.4e-54 yocL
NHPBOKKD_02031 6.6e-34
NHPBOKKD_02032 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NHPBOKKD_02033 1.1e-40 yozN
NHPBOKKD_02034 1.9e-36 yocN
NHPBOKKD_02035 4.2e-56 yozO S Bacterial PH domain
NHPBOKKD_02036 2.7e-31 yozC
NHPBOKKD_02037 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NHPBOKKD_02038 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NHPBOKKD_02039 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
NHPBOKKD_02040 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NHPBOKKD_02041 5.1e-168 yocS S -transporter
NHPBOKKD_02042 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NHPBOKKD_02043 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NHPBOKKD_02044 0.0 yojO P Von Willebrand factor
NHPBOKKD_02045 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
NHPBOKKD_02046 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NHPBOKKD_02047 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NHPBOKKD_02048 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NHPBOKKD_02049 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NHPBOKKD_02051 4.2e-245 norM V Multidrug efflux pump
NHPBOKKD_02052 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPBOKKD_02053 2.1e-125 yojG S deacetylase
NHPBOKKD_02054 2.2e-60 yojF S Protein of unknown function (DUF1806)
NHPBOKKD_02055 1.5e-43
NHPBOKKD_02056 3.5e-163 rarD S -transporter
NHPBOKKD_02057 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
NHPBOKKD_02058 3.4e-09
NHPBOKKD_02059 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
NHPBOKKD_02060 3.8e-66 yodA S tautomerase
NHPBOKKD_02061 1.7e-57 yodB K transcriptional
NHPBOKKD_02062 4.8e-108 yodC C nitroreductase
NHPBOKKD_02063 3.8e-113 mhqD S Carboxylesterase
NHPBOKKD_02064 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
NHPBOKKD_02065 6.2e-28 S Protein of unknown function (DUF3311)
NHPBOKKD_02066 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPBOKKD_02067 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NHPBOKKD_02068 1.7e-128 yodH Q Methyltransferase
NHPBOKKD_02069 5.2e-24 yodI
NHPBOKKD_02070 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NHPBOKKD_02071 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NHPBOKKD_02072 5.3e-09
NHPBOKKD_02073 3.6e-54 yodL S YodL-like
NHPBOKKD_02074 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
NHPBOKKD_02075 2.8e-24 yozD S YozD-like protein
NHPBOKKD_02077 1.4e-124 yodN
NHPBOKKD_02078 1.4e-36 yozE S Belongs to the UPF0346 family
NHPBOKKD_02079 2.9e-47 yokU S YokU-like protein, putative antitoxin
NHPBOKKD_02080 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
NHPBOKKD_02081 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NHPBOKKD_02082 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
NHPBOKKD_02083 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NHPBOKKD_02084 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHPBOKKD_02085 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NHPBOKKD_02088 2.9e-145 yiiD K acetyltransferase
NHPBOKKD_02089 1e-256 cgeD M maturation of the outermost layer of the spore
NHPBOKKD_02090 3.5e-38 cgeC
NHPBOKKD_02091 1.2e-65 cgeA
NHPBOKKD_02092 3.3e-188 cgeB S Spore maturation protein
NHPBOKKD_02093 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NHPBOKKD_02094 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
NHPBOKKD_02096 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHPBOKKD_02097 1.4e-10 K Cro/C1-type HTH DNA-binding domain
NHPBOKKD_02105 1.9e-168 S Calcineurin-like phosphoesterase
NHPBOKKD_02106 2.5e-30 sspB S spore protein
NHPBOKKD_02111 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
NHPBOKKD_02112 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NHPBOKKD_02113 6.1e-38 O Glutaredoxin
NHPBOKKD_02114 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPBOKKD_02115 3.3e-97 L HNH endonuclease
NHPBOKKD_02116 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPBOKKD_02117 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPBOKKD_02118 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NHPBOKKD_02119 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NHPBOKKD_02136 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
NHPBOKKD_02138 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
NHPBOKKD_02139 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
NHPBOKKD_02144 9.9e-115 DR0488 S protein conserved in bacteria
NHPBOKKD_02145 0.0 2.7.7.7 L DNA polymerase
NHPBOKKD_02146 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHPBOKKD_02147 1.2e-224 L DNA primase activity
NHPBOKKD_02148 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
NHPBOKKD_02149 1.4e-86
NHPBOKKD_02150 7.6e-180 L AAA domain
NHPBOKKD_02151 1.3e-170
NHPBOKKD_02156 0.0 M Parallel beta-helix repeats
NHPBOKKD_02157 7.7e-149 S Pfam:DUF867
NHPBOKKD_02160 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
NHPBOKKD_02161 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
NHPBOKKD_02162 2.3e-77
NHPBOKKD_02169 1e-44
NHPBOKKD_02171 1.5e-97 S Protein of unknown function (DUF1273)
NHPBOKKD_02173 3e-78 yoqH M LysM domain
NHPBOKKD_02176 8.8e-12 S Protein of unknown function (DUF2815)
NHPBOKKD_02177 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
NHPBOKKD_02188 1.1e-33 K Transcriptional regulator
NHPBOKKD_02189 2.1e-177
NHPBOKKD_02190 6e-263 S DNA-sulfur modification-associated
NHPBOKKD_02191 6.8e-198 L Belongs to the 'phage' integrase family
NHPBOKKD_02196 6.6e-106
NHPBOKKD_02198 1.2e-86
NHPBOKKD_02199 1.1e-96 S Super-infection exclusion protein B
NHPBOKKD_02204 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
NHPBOKKD_02205 3.8e-259
NHPBOKKD_02206 4.6e-35 K Cro/C1-type HTH DNA-binding domain
NHPBOKKD_02207 1.4e-256
NHPBOKKD_02209 5.9e-238
NHPBOKKD_02211 4e-17
NHPBOKKD_02212 5.7e-55 bldD K domain, Protein
NHPBOKKD_02215 0.0
NHPBOKKD_02216 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHPBOKKD_02218 2.6e-230
NHPBOKKD_02221 1.8e-175
NHPBOKKD_02222 0.0 gp17a S Terminase-like family
NHPBOKKD_02223 6.3e-282
NHPBOKKD_02224 2.1e-266
NHPBOKKD_02225 1.6e-94
NHPBOKKD_02226 5.7e-186
NHPBOKKD_02227 5.1e-81
NHPBOKKD_02228 1.1e-68
NHPBOKKD_02230 1.4e-121
NHPBOKKD_02231 2.6e-91
NHPBOKKD_02232 8.1e-131
NHPBOKKD_02233 1.6e-90
NHPBOKKD_02236 1e-57
NHPBOKKD_02237 1.1e-172
NHPBOKKD_02238 8.1e-07
NHPBOKKD_02239 2.5e-10 xkdX
NHPBOKKD_02240 2.5e-86
NHPBOKKD_02241 6.3e-70
NHPBOKKD_02242 2.1e-193 xerH A Belongs to the 'phage' integrase family
NHPBOKKD_02247 9.3e-116
NHPBOKKD_02248 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NHPBOKKD_02249 6.2e-145 S Phage tail protein
NHPBOKKD_02250 0.0 S Pfam Transposase IS66
NHPBOKKD_02251 6.4e-115
NHPBOKKD_02252 0.0 G Exopolysaccharide biosynthesis protein
NHPBOKKD_02253 6.5e-164
NHPBOKKD_02255 1.6e-186 3.5.1.28 M Ami_2
NHPBOKKD_02256 4.4e-32 bhlA S BhlA holin family
NHPBOKKD_02257 5.5e-40 S SPP1 phage holin
NHPBOKKD_02258 3.4e-74 O protein disulfide oxidoreductase activity
NHPBOKKD_02259 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPBOKKD_02260 1.2e-70 CO cell redox homeostasis
NHPBOKKD_02261 0.0 V Peptidase C39 family
NHPBOKKD_02264 1.9e-239 S impB/mucB/samB family C-terminal domain
NHPBOKKD_02265 5.8e-55 S YolD-like protein
NHPBOKKD_02266 1.3e-37
NHPBOKKD_02268 6.8e-09 S Domain of unknown function (DUF4879)
NHPBOKKD_02270 2.8e-99 J Acetyltransferase (GNAT) domain
NHPBOKKD_02271 3.2e-109 yokK S SMI1 / KNR4 family
NHPBOKKD_02272 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
NHPBOKKD_02273 1.2e-302 UW nuclease activity
NHPBOKKD_02274 6.7e-92 yokH G SMI1 / KNR4 family
NHPBOKKD_02275 4.1e-203
NHPBOKKD_02276 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
NHPBOKKD_02277 1.1e-83 S Bacterial PH domain
NHPBOKKD_02278 8.4e-156 aacC 2.3.1.81 V aminoglycoside
NHPBOKKD_02281 8.9e-95
NHPBOKKD_02282 1.6e-107
NHPBOKKD_02283 2.7e-307 yokA L Recombinase
NHPBOKKD_02284 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
NHPBOKKD_02285 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NHPBOKKD_02286 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NHPBOKKD_02287 1.6e-70 ypoP K transcriptional
NHPBOKKD_02288 2.6e-223 mepA V MATE efflux family protein
NHPBOKKD_02289 5.5e-29 ypmT S Uncharacterized ympT
NHPBOKKD_02290 5e-99 ypmS S protein conserved in bacteria
NHPBOKKD_02291 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NHPBOKKD_02292 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NHPBOKKD_02293 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NHPBOKKD_02294 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NHPBOKKD_02295 1.6e-185 pspF K Transcriptional regulator
NHPBOKKD_02296 4.2e-110 hlyIII S protein, Hemolysin III
NHPBOKKD_02297 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NHPBOKKD_02298 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NHPBOKKD_02299 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NHPBOKKD_02300 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NHPBOKKD_02301 7.8e-114 ypjP S YpjP-like protein
NHPBOKKD_02302 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NHPBOKKD_02303 1.7e-75 yphP S Belongs to the UPF0403 family
NHPBOKKD_02304 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NHPBOKKD_02305 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
NHPBOKKD_02306 3.1e-110 ypgQ S phosphohydrolase
NHPBOKKD_02307 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NHPBOKKD_02308 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NHPBOKKD_02309 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NHPBOKKD_02310 7.9e-31 cspD K Cold-shock protein
NHPBOKKD_02311 3.8e-16 degR
NHPBOKKD_02312 8.1e-31 S Protein of unknown function (DUF2564)
NHPBOKKD_02313 2.6e-27 ypeQ S Zinc-finger
NHPBOKKD_02314 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NHPBOKKD_02315 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NHPBOKKD_02316 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
NHPBOKKD_02318 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NHPBOKKD_02319 2e-07
NHPBOKKD_02320 1e-38 ypbS S Protein of unknown function (DUF2533)
NHPBOKKD_02321 0.0 ypbR S Dynamin family
NHPBOKKD_02322 5.1e-87 ypbQ S protein conserved in bacteria
NHPBOKKD_02323 4.4e-208 bcsA Q Naringenin-chalcone synthase
NHPBOKKD_02324 1.6e-228 pbuX F xanthine
NHPBOKKD_02325 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NHPBOKKD_02326 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NHPBOKKD_02327 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NHPBOKKD_02328 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NHPBOKKD_02329 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NHPBOKKD_02330 3.9e-187 ptxS K transcriptional
NHPBOKKD_02331 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NHPBOKKD_02332 5.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_02333 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NHPBOKKD_02335 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NHPBOKKD_02336 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NHPBOKKD_02337 3.3e-92 ypsA S Belongs to the UPF0398 family
NHPBOKKD_02338 1.3e-237 yprB L RNase_H superfamily
NHPBOKKD_02339 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NHPBOKKD_02340 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NHPBOKKD_02341 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
NHPBOKKD_02342 1.2e-48 yppG S YppG-like protein
NHPBOKKD_02344 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
NHPBOKKD_02347 2.6e-188 yppC S Protein of unknown function (DUF2515)
NHPBOKKD_02348 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NHPBOKKD_02349 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NHPBOKKD_02350 4.7e-93 ypoC
NHPBOKKD_02351 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NHPBOKKD_02352 5.7e-129 dnaD L DNA replication protein DnaD
NHPBOKKD_02353 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NHPBOKKD_02354 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NHPBOKKD_02355 3.4e-80 ypmB S protein conserved in bacteria
NHPBOKKD_02356 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NHPBOKKD_02357 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NHPBOKKD_02358 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NHPBOKKD_02359 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NHPBOKKD_02360 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NHPBOKKD_02361 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NHPBOKKD_02362 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NHPBOKKD_02363 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NHPBOKKD_02364 6.9e-130 bshB1 S proteins, LmbE homologs
NHPBOKKD_02365 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NHPBOKKD_02366 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NHPBOKKD_02367 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NHPBOKKD_02368 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NHPBOKKD_02369 6.1e-143 ypjB S sporulation protein
NHPBOKKD_02370 4.4e-98 ypjA S membrane
NHPBOKKD_02371 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NHPBOKKD_02372 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NHPBOKKD_02373 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NHPBOKKD_02374 8.5e-78 ypiF S Protein of unknown function (DUF2487)
NHPBOKKD_02375 2.8e-99 ypiB S Belongs to the UPF0302 family
NHPBOKKD_02376 4.1e-234 S COG0457 FOG TPR repeat
NHPBOKKD_02377 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NHPBOKKD_02378 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NHPBOKKD_02379 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NHPBOKKD_02380 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NHPBOKKD_02381 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NHPBOKKD_02382 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NHPBOKKD_02383 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NHPBOKKD_02384 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NHPBOKKD_02385 3.4e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NHPBOKKD_02386 4.6e-64 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NHPBOKKD_02387 1.7e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NHPBOKKD_02388 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NHPBOKKD_02389 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NHPBOKKD_02390 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NHPBOKKD_02391 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHPBOKKD_02392 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NHPBOKKD_02393 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NHPBOKKD_02394 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NHPBOKKD_02395 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NHPBOKKD_02396 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NHPBOKKD_02397 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NHPBOKKD_02398 5.4e-138 yphF
NHPBOKKD_02399 1.6e-18 yphE S Protein of unknown function (DUF2768)
NHPBOKKD_02400 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NHPBOKKD_02401 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NHPBOKKD_02402 1.6e-28 ypzH
NHPBOKKD_02403 2.5e-161 seaA S YIEGIA protein
NHPBOKKD_02404 1.3e-102 yphA
NHPBOKKD_02405 1e-07 S YpzI-like protein
NHPBOKKD_02406 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NHPBOKKD_02407 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
NHPBOKKD_02408 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NHPBOKKD_02409 1.8e-23 S Family of unknown function (DUF5359)
NHPBOKKD_02410 9.2e-113 ypfA M Flagellar protein YcgR
NHPBOKKD_02411 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NHPBOKKD_02412 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NHPBOKKD_02413 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
NHPBOKKD_02414 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NHPBOKKD_02415 7.3e-247 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NHPBOKKD_02416 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NHPBOKKD_02417 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NHPBOKKD_02418 2.8e-81 ypbF S Protein of unknown function (DUF2663)
NHPBOKKD_02419 4.6e-81 ypbE M Lysin motif
NHPBOKKD_02420 2.2e-100 ypbD S metal-dependent membrane protease
NHPBOKKD_02421 3.2e-286 recQ 3.6.4.12 L DNA helicase
NHPBOKKD_02422 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
NHPBOKKD_02423 4.7e-41 fer C Ferredoxin
NHPBOKKD_02424 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NHPBOKKD_02425 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPBOKKD_02426 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NHPBOKKD_02427 6.8e-201 rsiX
NHPBOKKD_02428 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_02429 0.0 resE 2.7.13.3 T Histidine kinase
NHPBOKKD_02430 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_02431 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NHPBOKKD_02432 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NHPBOKKD_02433 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NHPBOKKD_02434 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHPBOKKD_02435 1.9e-87 spmB S Spore maturation protein
NHPBOKKD_02436 3.5e-103 spmA S Spore maturation protein
NHPBOKKD_02437 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NHPBOKKD_02438 4e-98 ypuI S Protein of unknown function (DUF3907)
NHPBOKKD_02439 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NHPBOKKD_02440 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NHPBOKKD_02441 4.5e-94 ypuF S Domain of unknown function (DUF309)
NHPBOKKD_02442 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPBOKKD_02443 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NHPBOKKD_02444 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NHPBOKKD_02445 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
NHPBOKKD_02446 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NHPBOKKD_02447 6e-55 ypuD
NHPBOKKD_02448 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NHPBOKKD_02449 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NHPBOKKD_02450 1.5e-17 S SNARE associated Golgi protein
NHPBOKKD_02453 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NHPBOKKD_02454 1.3e-149 ypuA S Secreted protein
NHPBOKKD_02455 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NHPBOKKD_02456 1.4e-273 spoVAF EG Stage V sporulation protein AF
NHPBOKKD_02457 1.4e-110 spoVAEA S stage V sporulation protein
NHPBOKKD_02458 2.2e-57 spoVAEB S stage V sporulation protein
NHPBOKKD_02459 9e-192 spoVAD I Stage V sporulation protein AD
NHPBOKKD_02460 2.3e-78 spoVAC S stage V sporulation protein AC
NHPBOKKD_02461 1e-67 spoVAB S Stage V sporulation protein AB
NHPBOKKD_02462 7.4e-112 spoVAA S Stage V sporulation protein AA
NHPBOKKD_02463 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPBOKKD_02464 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NHPBOKKD_02465 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NHPBOKKD_02466 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NHPBOKKD_02467 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NHPBOKKD_02468 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NHPBOKKD_02469 2.6e-166 xerD L recombinase XerD
NHPBOKKD_02470 3.7e-37 S Protein of unknown function (DUF4227)
NHPBOKKD_02471 2.4e-80 fur P Belongs to the Fur family
NHPBOKKD_02472 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NHPBOKKD_02473 2e-32 yqkK
NHPBOKKD_02474 5.5e-242 mleA 1.1.1.38 C malic enzyme
NHPBOKKD_02475 3.1e-235 mleN C Na H antiporter
NHPBOKKD_02476 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NHPBOKKD_02477 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NHPBOKKD_02478 4.5e-58 ansR K Transcriptional regulator
NHPBOKKD_02479 3e-223 yqxK 3.6.4.12 L DNA helicase
NHPBOKKD_02480 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NHPBOKKD_02482 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NHPBOKKD_02483 4e-14 yqkE S Protein of unknown function (DUF3886)
NHPBOKKD_02484 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NHPBOKKD_02485 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NHPBOKKD_02486 2.8e-54 yqkB S Belongs to the HesB IscA family
NHPBOKKD_02487 4.7e-196 yqkA K GrpB protein
NHPBOKKD_02488 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NHPBOKKD_02489 3.6e-87 yqjY K acetyltransferase
NHPBOKKD_02490 2.2e-49 S YolD-like protein
NHPBOKKD_02491 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHPBOKKD_02493 5.2e-226 yqjV G Major Facilitator Superfamily
NHPBOKKD_02495 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPBOKKD_02496 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NHPBOKKD_02497 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NHPBOKKD_02498 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_02499 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPBOKKD_02500 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHPBOKKD_02501 0.0 rocB E arginine degradation protein
NHPBOKKD_02502 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NHPBOKKD_02503 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NHPBOKKD_02504 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NHPBOKKD_02505 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NHPBOKKD_02506 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHPBOKKD_02507 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NHPBOKKD_02508 4.5e-24 yqzJ
NHPBOKKD_02509 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHPBOKKD_02510 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
NHPBOKKD_02511 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NHPBOKKD_02512 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NHPBOKKD_02513 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NHPBOKKD_02515 1.4e-98 yqjB S protein conserved in bacteria
NHPBOKKD_02516 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
NHPBOKKD_02517 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NHPBOKKD_02518 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NHPBOKKD_02519 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
NHPBOKKD_02520 9.3e-77 yqiW S Belongs to the UPF0403 family
NHPBOKKD_02521 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NHPBOKKD_02522 7.9e-208 norA EGP Major facilitator Superfamily
NHPBOKKD_02523 2.6e-152 bmrR K helix_turn_helix, mercury resistance
NHPBOKKD_02524 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NHPBOKKD_02525 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NHPBOKKD_02526 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NHPBOKKD_02527 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NHPBOKKD_02528 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NHPBOKKD_02529 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NHPBOKKD_02530 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NHPBOKKD_02531 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NHPBOKKD_02532 4e-34 yqzF S Protein of unknown function (DUF2627)
NHPBOKKD_02533 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NHPBOKKD_02534 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NHPBOKKD_02535 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NHPBOKKD_02536 1.8e-212 mmgC I acyl-CoA dehydrogenase
NHPBOKKD_02537 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
NHPBOKKD_02538 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
NHPBOKKD_02539 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NHPBOKKD_02540 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NHPBOKKD_02541 5.9e-27
NHPBOKKD_02542 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NHPBOKKD_02544 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NHPBOKKD_02545 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NHPBOKKD_02546 0.0 recN L May be involved in recombinational repair of damaged DNA
NHPBOKKD_02547 1.7e-78 argR K Regulates arginine biosynthesis genes
NHPBOKKD_02548 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NHPBOKKD_02549 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NHPBOKKD_02550 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NHPBOKKD_02551 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHPBOKKD_02552 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NHPBOKKD_02553 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NHPBOKKD_02554 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NHPBOKKD_02555 2.1e-67 yqhY S protein conserved in bacteria
NHPBOKKD_02556 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NHPBOKKD_02557 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NHPBOKKD_02558 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NHPBOKKD_02559 6.9e-103 spoIIIAG S stage III sporulation protein AG
NHPBOKKD_02560 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NHPBOKKD_02561 1.3e-197 spoIIIAE S stage III sporulation protein AE
NHPBOKKD_02562 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NHPBOKKD_02563 7.6e-29 spoIIIAC S stage III sporulation protein AC
NHPBOKKD_02564 2.9e-85 spoIIIAB S Stage III sporulation protein
NHPBOKKD_02565 1.2e-171 spoIIIAA S stage III sporulation protein AA
NHPBOKKD_02566 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NHPBOKKD_02567 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NHPBOKKD_02568 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NHPBOKKD_02569 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NHPBOKKD_02570 2.3e-93 yqhR S Conserved membrane protein YqhR
NHPBOKKD_02571 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
NHPBOKKD_02572 2.2e-61 yqhP
NHPBOKKD_02573 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
NHPBOKKD_02574 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NHPBOKKD_02575 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NHPBOKKD_02576 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
NHPBOKKD_02577 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHPBOKKD_02578 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NHPBOKKD_02579 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NHPBOKKD_02580 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NHPBOKKD_02581 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
NHPBOKKD_02582 1.2e-24 sinI S Anti-repressor SinI
NHPBOKKD_02583 1e-54 sinR K transcriptional
NHPBOKKD_02584 2.3e-142 tasA S Cell division protein FtsN
NHPBOKKD_02585 6.7e-59 sipW 3.4.21.89 U Signal peptidase
NHPBOKKD_02586 2.1e-116 yqxM
NHPBOKKD_02587 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NHPBOKKD_02588 1.4e-26 yqzE S YqzE-like protein
NHPBOKKD_02589 3.7e-42 S ComG operon protein 7
NHPBOKKD_02590 5.5e-49 comGF U Putative Competence protein ComGF
NHPBOKKD_02591 1.1e-59 comGE
NHPBOKKD_02592 4.4e-71 gspH NU protein transport across the cell outer membrane
NHPBOKKD_02593 1.4e-47 comGC U Required for transformation and DNA binding
NHPBOKKD_02594 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
NHPBOKKD_02595 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NHPBOKKD_02597 7.2e-175 corA P Mg2 transporter protein
NHPBOKKD_02598 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NHPBOKKD_02599 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NHPBOKKD_02601 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NHPBOKKD_02602 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NHPBOKKD_02603 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPBOKKD_02604 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NHPBOKKD_02605 6.9e-50 yqgV S Thiamine-binding protein
NHPBOKKD_02606 2.7e-199 yqgU
NHPBOKKD_02607 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NHPBOKKD_02608 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHPBOKKD_02609 5.2e-181 glcK 2.7.1.2 G Glucokinase
NHPBOKKD_02610 3.1e-33 yqgQ S Protein conserved in bacteria
NHPBOKKD_02611 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NHPBOKKD_02612 2.5e-09 yqgO
NHPBOKKD_02613 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NHPBOKKD_02614 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NHPBOKKD_02615 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NHPBOKKD_02617 9.2e-51 yqzD
NHPBOKKD_02618 1.9e-75 yqzC S YceG-like family
NHPBOKKD_02619 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHPBOKKD_02620 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NHPBOKKD_02621 4.4e-158 pstA P Phosphate transport system permease
NHPBOKKD_02622 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
NHPBOKKD_02623 5.3e-151 pstS P Phosphate
NHPBOKKD_02624 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NHPBOKKD_02625 2.5e-231 yqgE EGP Major facilitator superfamily
NHPBOKKD_02626 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NHPBOKKD_02627 4e-73 yqgC S protein conserved in bacteria
NHPBOKKD_02628 8.5e-134 yqgB S Protein of unknown function (DUF1189)
NHPBOKKD_02629 2.2e-75 yqgA
NHPBOKKD_02630 5.2e-47 yqfZ M LysM domain
NHPBOKKD_02631 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NHPBOKKD_02632 4.3e-62 yqfX S membrane
NHPBOKKD_02633 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NHPBOKKD_02634 1.9e-77 zur P Belongs to the Fur family
NHPBOKKD_02635 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NHPBOKKD_02636 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NHPBOKKD_02637 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NHPBOKKD_02638 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NHPBOKKD_02639 2.9e-14 yqfQ S YqfQ-like protein
NHPBOKKD_02640 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NHPBOKKD_02641 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NHPBOKKD_02642 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
NHPBOKKD_02643 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NHPBOKKD_02644 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NHPBOKKD_02645 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NHPBOKKD_02646 4.5e-88 yaiI S Belongs to the UPF0178 family
NHPBOKKD_02647 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NHPBOKKD_02648 4.5e-112 ccpN K CBS domain
NHPBOKKD_02649 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NHPBOKKD_02650 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NHPBOKKD_02651 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
NHPBOKKD_02652 8.4e-19 S YqzL-like protein
NHPBOKKD_02653 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NHPBOKKD_02654 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NHPBOKKD_02655 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NHPBOKKD_02656 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NHPBOKKD_02657 0.0 yqfF S membrane-associated HD superfamily hydrolase
NHPBOKKD_02659 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
NHPBOKKD_02660 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NHPBOKKD_02661 2.7e-45 yqfC S sporulation protein YqfC
NHPBOKKD_02662 6e-25 yqfB
NHPBOKKD_02663 4.3e-122 yqfA S UPF0365 protein
NHPBOKKD_02664 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NHPBOKKD_02665 2.5e-61 yqeY S Yqey-like protein
NHPBOKKD_02666 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NHPBOKKD_02667 1.6e-158 yqeW P COG1283 Na phosphate symporter
NHPBOKKD_02668 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NHPBOKKD_02669 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NHPBOKKD_02670 5.4e-175 prmA J Methylates ribosomal protein L11
NHPBOKKD_02671 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NHPBOKKD_02672 0.0 dnaK O Heat shock 70 kDa protein
NHPBOKKD_02673 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NHPBOKKD_02674 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NHPBOKKD_02675 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
NHPBOKKD_02676 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NHPBOKKD_02677 1e-54 yqxA S Protein of unknown function (DUF3679)
NHPBOKKD_02678 6.9e-223 spoIIP M stage II sporulation protein P
NHPBOKKD_02679 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NHPBOKKD_02680 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NHPBOKKD_02681 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NHPBOKKD_02682 4.1e-15 S YqzM-like protein
NHPBOKKD_02683 0.0 comEC S Competence protein ComEC
NHPBOKKD_02684 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NHPBOKKD_02685 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NHPBOKKD_02686 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NHPBOKKD_02687 2.9e-139 yqeM Q Methyltransferase
NHPBOKKD_02688 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NHPBOKKD_02689 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NHPBOKKD_02690 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NHPBOKKD_02691 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NHPBOKKD_02692 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NHPBOKKD_02693 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NHPBOKKD_02694 5.3e-95 yqeG S hydrolase of the HAD superfamily
NHPBOKKD_02696 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NHPBOKKD_02697 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPBOKKD_02698 4.7e-106 yqeD S SNARE associated Golgi protein
NHPBOKKD_02699 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NHPBOKKD_02700 2.3e-133 yqeB
NHPBOKKD_02701 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NHPBOKKD_02702 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPBOKKD_02703 1.4e-281 cisA2 L Recombinase
NHPBOKKD_02704 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
NHPBOKKD_02705 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
NHPBOKKD_02706 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPBOKKD_02707 1.6e-54 arsR K ArsR family transcriptional regulator
NHPBOKKD_02708 1.1e-152 yqcI S YqcI/YcgG family
NHPBOKKD_02709 1.6e-96 S Tetratricopeptide repeat
NHPBOKKD_02712 3.8e-277 A Pre-toxin TG
NHPBOKKD_02713 1.1e-104 S Suppressor of fused protein (SUFU)
NHPBOKKD_02715 5e-60
NHPBOKKD_02717 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NHPBOKKD_02718 2.6e-68 S Bacteriophage holin family
NHPBOKKD_02719 4.8e-165 xepA
NHPBOKKD_02720 1.3e-23
NHPBOKKD_02721 4.1e-56 xkdW S XkdW protein
NHPBOKKD_02722 2e-221
NHPBOKKD_02723 9.6e-40
NHPBOKKD_02724 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NHPBOKKD_02725 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NHPBOKKD_02726 9.6e-71 xkdS S Protein of unknown function (DUF2634)
NHPBOKKD_02727 1.8e-38 xkdR S Protein of unknown function (DUF2577)
NHPBOKKD_02728 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
NHPBOKKD_02729 9e-114 xkdP S Lysin motif
NHPBOKKD_02730 0.0 xkdO L Transglycosylase SLT domain
NHPBOKKD_02731 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
NHPBOKKD_02733 3.6e-76 xkdM S Phage tail tube protein
NHPBOKKD_02734 5.5e-256 xkdK S Phage tail sheath C-terminal domain
NHPBOKKD_02735 3.2e-26
NHPBOKKD_02736 1.4e-77
NHPBOKKD_02737 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
NHPBOKKD_02738 6.7e-65 yqbH S Domain of unknown function (DUF3599)
NHPBOKKD_02739 2.1e-67 S Protein of unknown function (DUF3199)
NHPBOKKD_02740 3.6e-51 S YqbF, hypothetical protein domain
NHPBOKKD_02741 1.9e-167 xkdG S Phage capsid family
NHPBOKKD_02742 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NHPBOKKD_02743 2e-115
NHPBOKKD_02744 5.7e-169 S Phage Mu protein F like protein
NHPBOKKD_02745 5.9e-296 yqbA S portal protein
NHPBOKKD_02746 2.4e-253 S phage terminase, large subunit
NHPBOKKD_02747 6.3e-107 yqaS L DNA packaging
NHPBOKKD_02749 6.5e-81 L Transposase
NHPBOKKD_02750 1.6e-166
NHPBOKKD_02751 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
NHPBOKKD_02752 7.2e-74 rusA L Endodeoxyribonuclease RusA
NHPBOKKD_02754 5.9e-168 xkdC L IstB-like ATP binding protein
NHPBOKKD_02755 4.7e-123 3.1.3.16 L DnaD domain protein
NHPBOKKD_02756 2.5e-155 recT L RecT family
NHPBOKKD_02757 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
NHPBOKKD_02761 1.2e-103
NHPBOKKD_02763 6.5e-37 K Helix-turn-helix XRE-family like proteins
NHPBOKKD_02764 1.1e-56 K sequence-specific DNA binding
NHPBOKKD_02766 1e-101 adk 2.7.4.3 F adenylate kinase activity
NHPBOKKD_02767 1.4e-100 yqaB E IrrE N-terminal-like domain
NHPBOKKD_02768 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NHPBOKKD_02769 2e-68 psiE S Protein PsiE homolog
NHPBOKKD_02770 9e-237 yrkQ T Histidine kinase
NHPBOKKD_02771 1.1e-127 T Transcriptional regulator
NHPBOKKD_02772 8.2e-224 yrkO P Protein of unknown function (DUF418)
NHPBOKKD_02773 6e-105 yrkN K Acetyltransferase (GNAT) family
NHPBOKKD_02774 1.5e-97 ywrO S Flavodoxin-like fold
NHPBOKKD_02775 2.8e-79 S Protein of unknown function with HXXEE motif
NHPBOKKD_02776 4.3e-117 yrkJ S membrane transporter protein
NHPBOKKD_02777 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
NHPBOKKD_02778 1.1e-219 yrkH P Rhodanese Homology Domain
NHPBOKKD_02779 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
NHPBOKKD_02780 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
NHPBOKKD_02781 7.8e-39 yrkD S protein conserved in bacteria
NHPBOKKD_02782 2.6e-108 yrkC G Cupin domain
NHPBOKKD_02783 4.8e-151 bltR K helix_turn_helix, mercury resistance
NHPBOKKD_02784 3.5e-211 blt EGP Major facilitator Superfamily
NHPBOKKD_02785 1.4e-83 bltD 2.3.1.57 K FR47-like protein
NHPBOKKD_02786 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NHPBOKKD_02787 2.1e-17 S YrzO-like protein
NHPBOKKD_02788 1.7e-171 yrdR EG EamA-like transporter family
NHPBOKKD_02789 5.9e-160 yrdQ K Transcriptional regulator
NHPBOKKD_02790 2e-199 trkA P Oxidoreductase
NHPBOKKD_02791 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
NHPBOKKD_02792 1.3e-66 yodA S tautomerase
NHPBOKKD_02793 7.7e-163 gltR K LysR substrate binding domain
NHPBOKKD_02795 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
NHPBOKKD_02796 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NHPBOKKD_02797 3.3e-138 azlC E AzlC protein
NHPBOKKD_02798 2.2e-79 bkdR K helix_turn_helix ASNC type
NHPBOKKD_02799 4.1e-46 yrdF K ribonuclease inhibitor
NHPBOKKD_02800 4.1e-231 cypA C Cytochrome P450
NHPBOKKD_02802 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
NHPBOKKD_02803 1.9e-57 S Protein of unknown function (DUF2568)
NHPBOKKD_02804 1.2e-91 yrdA S DinB family
NHPBOKKD_02805 7.6e-168 aadK G Streptomycin adenylyltransferase
NHPBOKKD_02806 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NHPBOKKD_02807 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NHPBOKKD_02808 3e-125 yrpD S Domain of unknown function, YrpD
NHPBOKKD_02810 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NHPBOKKD_02811 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_02812 4.5e-188 yrpG C Aldo/keto reductase family
NHPBOKKD_02813 9.5e-226 yraO C Citrate transporter
NHPBOKKD_02814 1.2e-163 yraN K Transcriptional regulator
NHPBOKKD_02815 2.4e-206 yraM S PrpF protein
NHPBOKKD_02817 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NHPBOKKD_02818 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPBOKKD_02819 3.2e-155 S Alpha beta hydrolase
NHPBOKKD_02820 1.7e-60 T sh3 domain protein
NHPBOKKD_02821 2.4e-61 T sh3 domain protein
NHPBOKKD_02822 1.3e-66 E Glyoxalase-like domain
NHPBOKKD_02823 5.3e-37 yraG
NHPBOKKD_02824 6.4e-63 yraF M Spore coat protein
NHPBOKKD_02825 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NHPBOKKD_02826 2.6e-26 yraE
NHPBOKKD_02827 1.1e-49 yraD M Spore coat protein
NHPBOKKD_02828 4.3e-47 yraB K helix_turn_helix, mercury resistance
NHPBOKKD_02829 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
NHPBOKKD_02830 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
NHPBOKKD_02831 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NHPBOKKD_02832 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NHPBOKKD_02833 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NHPBOKKD_02834 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NHPBOKKD_02835 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NHPBOKKD_02836 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
NHPBOKKD_02837 0.0 levR K PTS system fructose IIA component
NHPBOKKD_02838 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NHPBOKKD_02839 3.6e-106 yrhP E LysE type translocator
NHPBOKKD_02840 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
NHPBOKKD_02841 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_02842 1.7e-151 rsiV S Protein of unknown function (DUF3298)
NHPBOKKD_02843 0.0 yrhL I Acyltransferase family
NHPBOKKD_02844 1.5e-46 yrhK S YrhK-like protein
NHPBOKKD_02845 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NHPBOKKD_02846 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NHPBOKKD_02847 4.5e-97 yrhH Q methyltransferase
NHPBOKKD_02850 1.8e-142 focA P Formate nitrite
NHPBOKKD_02851 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
NHPBOKKD_02852 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NHPBOKKD_02853 1.4e-78 yrhD S Protein of unknown function (DUF1641)
NHPBOKKD_02854 4.6e-35 yrhC S YrhC-like protein
NHPBOKKD_02855 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NHPBOKKD_02856 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NHPBOKKD_02857 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NHPBOKKD_02858 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NHPBOKKD_02859 7e-27 yrzA S Protein of unknown function (DUF2536)
NHPBOKKD_02860 4.2e-63 yrrS S Protein of unknown function (DUF1510)
NHPBOKKD_02861 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NHPBOKKD_02862 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NHPBOKKD_02863 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NHPBOKKD_02864 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NHPBOKKD_02865 7.8e-174 yegQ O Peptidase U32
NHPBOKKD_02866 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
NHPBOKKD_02867 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NHPBOKKD_02868 1.2e-45 yrzB S Belongs to the UPF0473 family
NHPBOKKD_02869 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NHPBOKKD_02870 1.7e-41 yrzL S Belongs to the UPF0297 family
NHPBOKKD_02871 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NHPBOKKD_02872 2.7e-170 yrrI S AI-2E family transporter
NHPBOKKD_02873 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NHPBOKKD_02874 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
NHPBOKKD_02875 3.6e-109 gluC P ABC transporter
NHPBOKKD_02876 7.6e-107 glnP P ABC transporter
NHPBOKKD_02877 8e-08 S Protein of unknown function (DUF3918)
NHPBOKKD_02878 9.8e-31 yrzR
NHPBOKKD_02879 1.8e-83 yrrD S protein conserved in bacteria
NHPBOKKD_02880 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NHPBOKKD_02881 1.4e-15 S COG0457 FOG TPR repeat
NHPBOKKD_02882 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NHPBOKKD_02883 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
NHPBOKKD_02884 1.2e-70 cymR K Transcriptional regulator
NHPBOKKD_02885 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NHPBOKKD_02886 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NHPBOKKD_02887 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NHPBOKKD_02888 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
NHPBOKKD_02890 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
NHPBOKKD_02891 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NHPBOKKD_02892 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NHPBOKKD_02893 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NHPBOKKD_02894 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NHPBOKKD_02895 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NHPBOKKD_02896 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NHPBOKKD_02897 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NHPBOKKD_02898 9.4e-49 yrzD S Post-transcriptional regulator
NHPBOKKD_02899 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPBOKKD_02900 2.2e-114 yrbG S membrane
NHPBOKKD_02901 1.2e-74 yrzE S Protein of unknown function (DUF3792)
NHPBOKKD_02902 1.1e-38 yajC U Preprotein translocase subunit YajC
NHPBOKKD_02903 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NHPBOKKD_02904 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NHPBOKKD_02905 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NHPBOKKD_02906 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NHPBOKKD_02907 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NHPBOKKD_02908 4.8e-93 bofC S BofC C-terminal domain
NHPBOKKD_02909 5.3e-253 csbX EGP Major facilitator Superfamily
NHPBOKKD_02910 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NHPBOKKD_02911 6.5e-119 yrzF T serine threonine protein kinase
NHPBOKKD_02913 2.6e-35 S Family of unknown function (DUF5412)
NHPBOKKD_02914 1.8e-262 alsT E Sodium alanine symporter
NHPBOKKD_02915 1.9e-127 yebC K transcriptional regulatory protein
NHPBOKKD_02916 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPBOKKD_02917 9.8e-158 safA M spore coat assembly protein SafA
NHPBOKKD_02918 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NHPBOKKD_02919 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NHPBOKKD_02920 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NHPBOKKD_02921 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
NHPBOKKD_02922 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NHPBOKKD_02923 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
NHPBOKKD_02924 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NHPBOKKD_02925 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NHPBOKKD_02926 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NHPBOKKD_02927 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NHPBOKKD_02928 4.1e-56 ysxB J ribosomal protein
NHPBOKKD_02929 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NHPBOKKD_02930 9.2e-161 spoIVFB S Stage IV sporulation protein
NHPBOKKD_02931 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NHPBOKKD_02932 2.5e-144 minD D Belongs to the ParA family
NHPBOKKD_02933 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NHPBOKKD_02934 1.4e-84 mreD M shape-determining protein
NHPBOKKD_02935 2.8e-157 mreC M Involved in formation and maintenance of cell shape
NHPBOKKD_02936 1.8e-184 mreB D Rod shape-determining protein MreB
NHPBOKKD_02937 5.9e-126 radC E Belongs to the UPF0758 family
NHPBOKKD_02938 2.8e-102 maf D septum formation protein Maf
NHPBOKKD_02939 1.1e-168 spoIIB S Sporulation related domain
NHPBOKKD_02940 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NHPBOKKD_02941 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NHPBOKKD_02942 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NHPBOKKD_02943 1.6e-25
NHPBOKKD_02944 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NHPBOKKD_02945 1.9e-226 spoVID M stage VI sporulation protein D
NHPBOKKD_02946 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NHPBOKKD_02947 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
NHPBOKKD_02948 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NHPBOKKD_02949 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NHPBOKKD_02950 3.6e-146 hemX O cytochrome C
NHPBOKKD_02951 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NHPBOKKD_02952 1.4e-89 ysxD
NHPBOKKD_02953 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NHPBOKKD_02954 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NHPBOKKD_02955 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NHPBOKKD_02956 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NHPBOKKD_02957 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NHPBOKKD_02958 2.3e-187 ysoA H Tetratricopeptide repeat
NHPBOKKD_02959 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHPBOKKD_02960 9.1e-46 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHPBOKKD_02961 1.2e-242 tetL EGP Major Facilitator Superfamily
NHPBOKKD_02962 1.8e-220 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NHPBOKKD_02963 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NHPBOKKD_02964 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NHPBOKKD_02965 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NHPBOKKD_02966 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NHPBOKKD_02967 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NHPBOKKD_02969 7.6e-82 ysnE K acetyltransferase
NHPBOKKD_02970 9.1e-134 ysnF S protein conserved in bacteria
NHPBOKKD_02972 1.4e-92 ysnB S Phosphoesterase
NHPBOKKD_02973 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NHPBOKKD_02974 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NHPBOKKD_02975 2.9e-196 gerM S COG5401 Spore germination protein
NHPBOKKD_02976 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NHPBOKKD_02977 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_02978 3.3e-30 gerE K Transcriptional regulator
NHPBOKKD_02979 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NHPBOKKD_02980 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NHPBOKKD_02981 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NHPBOKKD_02982 2.4e-107 sdhC C succinate dehydrogenase
NHPBOKKD_02983 1.2e-79 yslB S Protein of unknown function (DUF2507)
NHPBOKKD_02984 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NHPBOKKD_02985 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NHPBOKKD_02986 2e-52 trxA O Belongs to the thioredoxin family
NHPBOKKD_02987 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NHPBOKKD_02989 4.2e-178 etfA C Electron transfer flavoprotein
NHPBOKKD_02990 1.2e-135 etfB C Electron transfer flavoprotein
NHPBOKKD_02991 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NHPBOKKD_02992 2.7e-100 fadR K Transcriptional regulator
NHPBOKKD_02993 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NHPBOKKD_02994 7.3e-68 yshE S membrane
NHPBOKKD_02995 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NHPBOKKD_02996 0.0 polX L COG1796 DNA polymerase IV (family X)
NHPBOKKD_02997 1.3e-85 cvpA S membrane protein, required for colicin V production
NHPBOKKD_02998 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NHPBOKKD_02999 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NHPBOKKD_03000 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHPBOKKD_03001 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NHPBOKKD_03002 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NHPBOKKD_03003 2.6e-32 sspI S Belongs to the SspI family
NHPBOKKD_03004 4.4e-208 ysfB KT regulator
NHPBOKKD_03005 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
NHPBOKKD_03006 5.6e-258 glcF C Glycolate oxidase
NHPBOKKD_03007 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
NHPBOKKD_03009 0.0 cstA T Carbon starvation protein
NHPBOKKD_03010 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NHPBOKKD_03011 3.4e-144 araQ G transport system permease
NHPBOKKD_03012 1.4e-167 araP G carbohydrate transport
NHPBOKKD_03013 2.8e-254 araN G carbohydrate transport
NHPBOKKD_03014 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NHPBOKKD_03015 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NHPBOKKD_03016 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NHPBOKKD_03017 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NHPBOKKD_03018 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NHPBOKKD_03019 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NHPBOKKD_03020 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
NHPBOKKD_03021 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NHPBOKKD_03022 7.5e-45 ysdA S Membrane
NHPBOKKD_03023 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NHPBOKKD_03024 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NHPBOKKD_03025 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NHPBOKKD_03027 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NHPBOKKD_03028 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NHPBOKKD_03029 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
NHPBOKKD_03030 0.0 lytS 2.7.13.3 T Histidine kinase
NHPBOKKD_03031 1.5e-149 ysaA S HAD-hyrolase-like
NHPBOKKD_03032 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHPBOKKD_03033 3.8e-159 ytxC S YtxC-like family
NHPBOKKD_03034 4.9e-111 ytxB S SNARE associated Golgi protein
NHPBOKKD_03035 3e-173 dnaI L Primosomal protein DnaI
NHPBOKKD_03036 3.5e-266 dnaB L Membrane attachment protein
NHPBOKKD_03037 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NHPBOKKD_03038 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NHPBOKKD_03039 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHPBOKKD_03040 9.9e-67 ytcD K Transcriptional regulator
NHPBOKKD_03041 4.9e-205 ytbD EGP Major facilitator Superfamily
NHPBOKKD_03042 8.9e-161 ytbE S reductase
NHPBOKKD_03043 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NHPBOKKD_03044 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NHPBOKKD_03045 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NHPBOKKD_03046 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NHPBOKKD_03047 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NHPBOKKD_03048 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_03049 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NHPBOKKD_03050 1.8e-242 icd 1.1.1.42 C isocitrate
NHPBOKKD_03051 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
NHPBOKKD_03052 4.7e-71 yeaL S membrane
NHPBOKKD_03053 2.6e-192 ytvI S sporulation integral membrane protein YtvI
NHPBOKKD_03054 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NHPBOKKD_03055 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NHPBOKKD_03056 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NHPBOKKD_03057 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NHPBOKKD_03058 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NHPBOKKD_03059 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NHPBOKKD_03060 0.0 dnaE 2.7.7.7 L DNA polymerase
NHPBOKKD_03061 3.2e-56 ytrH S Sporulation protein YtrH
NHPBOKKD_03062 8.2e-69 ytrI
NHPBOKKD_03063 9.2e-29
NHPBOKKD_03064 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NHPBOKKD_03065 2.4e-47 ytpI S YtpI-like protein
NHPBOKKD_03066 8e-241 ytoI K transcriptional regulator containing CBS domains
NHPBOKKD_03067 1.2e-158 ytnM S membrane transporter protein
NHPBOKKD_03068 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
NHPBOKKD_03069 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
NHPBOKKD_03070 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPBOKKD_03071 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
NHPBOKKD_03072 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPBOKKD_03073 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NHPBOKKD_03074 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
NHPBOKKD_03075 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
NHPBOKKD_03076 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
NHPBOKKD_03077 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
NHPBOKKD_03078 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
NHPBOKKD_03079 2.9e-173 ytlI K LysR substrate binding domain
NHPBOKKD_03080 1.7e-130 ytkL S Belongs to the UPF0173 family
NHPBOKKD_03081 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_03083 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
NHPBOKKD_03084 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NHPBOKKD_03085 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NHPBOKKD_03086 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NHPBOKKD_03087 7e-165 ytxK 2.1.1.72 L DNA methylase
NHPBOKKD_03088 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NHPBOKKD_03089 8.7e-70 ytfJ S Sporulation protein YtfJ
NHPBOKKD_03090 5.6e-116 ytfI S Protein of unknown function (DUF2953)
NHPBOKKD_03091 1.3e-87 yteJ S RDD family
NHPBOKKD_03092 2.4e-181 sppA OU signal peptide peptidase SppA
NHPBOKKD_03093 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NHPBOKKD_03094 0.0 ytcJ S amidohydrolase
NHPBOKKD_03095 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NHPBOKKD_03096 2e-29 sspB S spore protein
NHPBOKKD_03097 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NHPBOKKD_03098 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
NHPBOKKD_03099 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NHPBOKKD_03100 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NHPBOKKD_03101 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NHPBOKKD_03102 3.4e-109 yttP K Transcriptional regulator
NHPBOKKD_03103 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NHPBOKKD_03104 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NHPBOKKD_03105 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NHPBOKKD_03107 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHPBOKKD_03108 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NHPBOKKD_03109 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NHPBOKKD_03110 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
NHPBOKKD_03111 1.9e-225 acuC BQ histone deacetylase
NHPBOKKD_03112 1.4e-125 motS N Flagellar motor protein
NHPBOKKD_03113 7.1e-147 motA N flagellar motor
NHPBOKKD_03114 1.7e-182 ccpA K catabolite control protein A
NHPBOKKD_03115 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NHPBOKKD_03116 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
NHPBOKKD_03117 6.6e-17 ytxH S COG4980 Gas vesicle protein
NHPBOKKD_03118 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NHPBOKKD_03119 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NHPBOKKD_03120 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NHPBOKKD_03121 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NHPBOKKD_03122 9.8e-149 ytpQ S Belongs to the UPF0354 family
NHPBOKKD_03123 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NHPBOKKD_03124 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NHPBOKKD_03125 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NHPBOKKD_03126 9.8e-52 ytzB S small secreted protein
NHPBOKKD_03127 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NHPBOKKD_03128 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NHPBOKKD_03129 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NHPBOKKD_03130 2e-45 ytzH S YtzH-like protein
NHPBOKKD_03131 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NHPBOKKD_03132 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NHPBOKKD_03133 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NHPBOKKD_03134 1.3e-165 ytlQ
NHPBOKKD_03135 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NHPBOKKD_03136 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NHPBOKKD_03137 7.1e-272 pepV 3.5.1.18 E Dipeptidase
NHPBOKKD_03138 7.2e-226 pbuO S permease
NHPBOKKD_03139 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
NHPBOKKD_03140 4.3e-132 ythP V ABC transporter
NHPBOKKD_03141 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NHPBOKKD_03142 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NHPBOKKD_03143 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPBOKKD_03144 8.2e-232 ytfP S HI0933-like protein
NHPBOKKD_03145 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NHPBOKKD_03146 3.1e-26 yteV S Sporulation protein Cse60
NHPBOKKD_03147 4.8e-117 yteU S Integral membrane protein
NHPBOKKD_03148 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NHPBOKKD_03149 4.6e-73 yteS G transport
NHPBOKKD_03150 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NHPBOKKD_03151 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NHPBOKKD_03152 0.0 ytdP K Transcriptional regulator
NHPBOKKD_03153 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NHPBOKKD_03154 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
NHPBOKKD_03155 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NHPBOKKD_03156 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
NHPBOKKD_03157 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NHPBOKKD_03158 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NHPBOKKD_03159 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NHPBOKKD_03160 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NHPBOKKD_03161 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NHPBOKKD_03162 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
NHPBOKKD_03163 2.3e-190 msmR K Transcriptional regulator
NHPBOKKD_03164 2.1e-246 msmE G Bacterial extracellular solute-binding protein
NHPBOKKD_03165 1.5e-169 amyD P ABC transporter
NHPBOKKD_03166 1.5e-144 amyC P ABC transporter (permease)
NHPBOKKD_03167 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NHPBOKKD_03168 2.1e-51 ytwF P Sulfurtransferase
NHPBOKKD_03169 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NHPBOKKD_03170 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NHPBOKKD_03171 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NHPBOKKD_03172 2.1e-211 yttB EGP Major facilitator Superfamily
NHPBOKKD_03173 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
NHPBOKKD_03174 0.0 bceB V ABC transporter (permease)
NHPBOKKD_03175 1.1e-138 bceA V ABC transporter, ATP-binding protein
NHPBOKKD_03176 5.6e-186 T PhoQ Sensor
NHPBOKKD_03177 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_03178 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NHPBOKKD_03179 3.1e-127 ytrE V ABC transporter, ATP-binding protein
NHPBOKKD_03180 5.9e-148
NHPBOKKD_03181 6.1e-169 P ABC-2 family transporter protein
NHPBOKKD_03182 1.1e-161 ytrB P abc transporter atp-binding protein
NHPBOKKD_03183 5.1e-66 ytrA K GntR family transcriptional regulator
NHPBOKKD_03185 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NHPBOKKD_03186 2.1e-190 yhcC S Fe-S oxidoreductase
NHPBOKKD_03187 3.3e-106 ytqB J Putative rRNA methylase
NHPBOKKD_03188 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NHPBOKKD_03189 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NHPBOKKD_03190 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NHPBOKKD_03191 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NHPBOKKD_03192 0.0 asnB 6.3.5.4 E Asparagine synthase
NHPBOKKD_03193 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NHPBOKKD_03194 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NHPBOKKD_03195 1.2e-38 ytmB S Protein of unknown function (DUF2584)
NHPBOKKD_03196 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NHPBOKKD_03197 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NHPBOKKD_03198 1.4e-144 ytlC P ABC transporter
NHPBOKKD_03199 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NHPBOKKD_03200 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NHPBOKKD_03201 5.4e-63 ytkC S Bacteriophage holin family
NHPBOKKD_03202 2.1e-76 dps P Belongs to the Dps family
NHPBOKKD_03204 3.6e-73 ytkA S YtkA-like
NHPBOKKD_03205 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NHPBOKKD_03206 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NHPBOKKD_03207 3.6e-41 rpmE2 J Ribosomal protein L31
NHPBOKKD_03208 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
NHPBOKKD_03209 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NHPBOKKD_03210 1.1e-24 S Domain of Unknown Function (DUF1540)
NHPBOKKD_03211 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NHPBOKKD_03212 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NHPBOKKD_03213 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NHPBOKKD_03214 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
NHPBOKKD_03215 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NHPBOKKD_03216 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NHPBOKKD_03217 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NHPBOKKD_03218 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NHPBOKKD_03219 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NHPBOKKD_03220 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
NHPBOKKD_03221 2.6e-132 dksA T COG1734 DnaK suppressor protein
NHPBOKKD_03222 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
NHPBOKKD_03223 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHPBOKKD_03224 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NHPBOKKD_03225 3.6e-235 ytcC M Glycosyltransferase Family 4
NHPBOKKD_03227 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
NHPBOKKD_03228 1.8e-217 cotSA M Glycosyl transferases group 1
NHPBOKKD_03229 1.8e-206 cotI S Spore coat protein
NHPBOKKD_03230 9.9e-77 tspO T membrane
NHPBOKKD_03231 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NHPBOKKD_03232 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NHPBOKKD_03233 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NHPBOKKD_03234 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NHPBOKKD_03235 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NHPBOKKD_03244 7.8e-08
NHPBOKKD_03245 1.3e-09
NHPBOKKD_03252 2e-08
NHPBOKKD_03257 3.4e-39 S COG NOG14552 non supervised orthologous group
NHPBOKKD_03258 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NHPBOKKD_03259 3.4e-94 M1-753 M FR47-like protein
NHPBOKKD_03260 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
NHPBOKKD_03261 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NHPBOKKD_03262 3.9e-84 yuaE S DinB superfamily
NHPBOKKD_03263 7.9e-108 yuaD
NHPBOKKD_03264 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NHPBOKKD_03265 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NHPBOKKD_03266 1.1e-95 yuaC K Belongs to the GbsR family
NHPBOKKD_03267 2.2e-91 yuaB
NHPBOKKD_03268 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
NHPBOKKD_03269 5.4e-237 ktrB P Potassium
NHPBOKKD_03270 1e-38 yiaA S yiaA/B two helix domain
NHPBOKKD_03271 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHPBOKKD_03272 6.2e-277 yubD P Major Facilitator Superfamily
NHPBOKKD_03273 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NHPBOKKD_03275 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NHPBOKKD_03276 6.3e-197 yubA S transporter activity
NHPBOKKD_03277 3.3e-183 ygjR S Oxidoreductase
NHPBOKKD_03278 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NHPBOKKD_03279 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NHPBOKKD_03280 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NHPBOKKD_03281 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NHPBOKKD_03282 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NHPBOKKD_03283 5.1e-239 mcpA NT chemotaxis protein
NHPBOKKD_03284 2.2e-295 mcpA NT chemotaxis protein
NHPBOKKD_03285 1.5e-222 mcpA NT chemotaxis protein
NHPBOKKD_03286 3.2e-225 mcpA NT chemotaxis protein
NHPBOKKD_03287 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NHPBOKKD_03288 1e-35
NHPBOKKD_03289 2.1e-72 yugU S Uncharacterised protein family UPF0047
NHPBOKKD_03290 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NHPBOKKD_03291 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NHPBOKKD_03292 1.4e-116 yugP S Zn-dependent protease
NHPBOKKD_03293 4.6e-39
NHPBOKKD_03294 1.1e-53 mstX S Membrane-integrating protein Mistic
NHPBOKKD_03295 1.7e-182 yugO P COG1226 Kef-type K transport systems
NHPBOKKD_03296 1.3e-72 yugN S YugN-like family
NHPBOKKD_03298 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NHPBOKKD_03299 2.8e-229 yugK C Dehydrogenase
NHPBOKKD_03300 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NHPBOKKD_03301 1.1e-34 yuzA S Domain of unknown function (DUF378)
NHPBOKKD_03302 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NHPBOKKD_03303 4.3e-200 yugH 2.6.1.1 E Aminotransferase
NHPBOKKD_03304 1.6e-85 alaR K Transcriptional regulator
NHPBOKKD_03305 1e-156 yugF I Hydrolase
NHPBOKKD_03306 9.8e-42 yugE S Domain of unknown function (DUF1871)
NHPBOKKD_03307 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NHPBOKKD_03308 7.8e-233 T PhoQ Sensor
NHPBOKKD_03309 2e-70 kapB G Kinase associated protein B
NHPBOKKD_03310 1.9e-115 kapD L the KinA pathway to sporulation
NHPBOKKD_03312 3.5e-186 yuxJ EGP Major facilitator Superfamily
NHPBOKKD_03313 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NHPBOKKD_03314 6.3e-75 yuxK S protein conserved in bacteria
NHPBOKKD_03315 6.3e-78 yufK S Family of unknown function (DUF5366)
NHPBOKKD_03316 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NHPBOKKD_03317 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
NHPBOKKD_03318 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NHPBOKKD_03319 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NHPBOKKD_03320 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
NHPBOKKD_03321 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
NHPBOKKD_03322 1.3e-233 maeN C COG3493 Na citrate symporter
NHPBOKKD_03323 1.9e-14
NHPBOKKD_03324 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NHPBOKKD_03325 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPBOKKD_03326 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPBOKKD_03327 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPBOKKD_03328 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPBOKKD_03329 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NHPBOKKD_03330 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NHPBOKKD_03331 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
NHPBOKKD_03332 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPBOKKD_03333 0.0 comP 2.7.13.3 T Histidine kinase
NHPBOKKD_03335 2.5e-162 comQ H Polyprenyl synthetase
NHPBOKKD_03337 1.1e-22 yuzC
NHPBOKKD_03338 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NHPBOKKD_03339 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NHPBOKKD_03340 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
NHPBOKKD_03341 1.6e-67 yueI S Protein of unknown function (DUF1694)
NHPBOKKD_03342 7.4e-39 yueH S YueH-like protein
NHPBOKKD_03343 2.1e-32 yueG S Spore germination protein gerPA/gerPF
NHPBOKKD_03344 1.9e-190 yueF S transporter activity
NHPBOKKD_03345 6.1e-72 S Protein of unknown function (DUF2283)
NHPBOKKD_03346 2.9e-24 S Protein of unknown function (DUF2642)
NHPBOKKD_03347 4.8e-96 yueE S phosphohydrolase
NHPBOKKD_03348 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_03349 6.6e-65 yueC S Family of unknown function (DUF5383)
NHPBOKKD_03350 0.0 esaA S type VII secretion protein EsaA
NHPBOKKD_03351 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NHPBOKKD_03352 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
NHPBOKKD_03353 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NHPBOKKD_03354 2.8e-45 esxA S Belongs to the WXG100 family
NHPBOKKD_03355 6.5e-229 yukF QT Transcriptional regulator
NHPBOKKD_03356 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NHPBOKKD_03357 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NHPBOKKD_03358 3.8e-36 mbtH S MbtH-like protein
NHPBOKKD_03359 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_03360 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NHPBOKKD_03361 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NHPBOKKD_03362 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
NHPBOKKD_03363 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_03364 1.3e-167 besA S Putative esterase
NHPBOKKD_03365 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NHPBOKKD_03366 1.1e-93 bioY S Biotin biosynthesis protein
NHPBOKKD_03367 3.9e-211 yuiF S antiporter
NHPBOKKD_03368 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NHPBOKKD_03369 1.2e-77 yuiD S protein conserved in bacteria
NHPBOKKD_03370 9.5e-118 yuiC S protein conserved in bacteria
NHPBOKKD_03371 8.4e-27 yuiB S Putative membrane protein
NHPBOKKD_03372 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
NHPBOKKD_03373 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
NHPBOKKD_03375 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NHPBOKKD_03376 9e-118 paiB K Putative FMN-binding domain
NHPBOKKD_03377 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPBOKKD_03378 3.7e-63 erpA S Belongs to the HesB IscA family
NHPBOKKD_03379 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NHPBOKKD_03380 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHPBOKKD_03381 3.2e-39 yuzB S Belongs to the UPF0349 family
NHPBOKKD_03382 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NHPBOKKD_03383 3.5e-57 yuzD S protein conserved in bacteria
NHPBOKKD_03384 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NHPBOKKD_03385 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NHPBOKKD_03386 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NHPBOKKD_03387 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NHPBOKKD_03388 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
NHPBOKKD_03389 2e-199 yutH S Spore coat protein
NHPBOKKD_03390 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NHPBOKKD_03391 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NHPBOKKD_03392 3.9e-75 yutE S Protein of unknown function DUF86
NHPBOKKD_03393 9.7e-48 yutD S protein conserved in bacteria
NHPBOKKD_03394 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NHPBOKKD_03395 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NHPBOKKD_03396 4.5e-196 lytH M Peptidase, M23
NHPBOKKD_03397 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
NHPBOKKD_03398 4.8e-48 yunC S Domain of unknown function (DUF1805)
NHPBOKKD_03399 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NHPBOKKD_03400 2e-141 yunE S membrane transporter protein
NHPBOKKD_03401 4.3e-171 yunF S Protein of unknown function DUF72
NHPBOKKD_03402 3e-62 yunG
NHPBOKKD_03403 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NHPBOKKD_03404 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
NHPBOKKD_03405 2.1e-236 pbuX F Permease family
NHPBOKKD_03406 1.3e-224 pbuX F xanthine
NHPBOKKD_03407 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NHPBOKKD_03408 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NHPBOKKD_03409 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NHPBOKKD_03410 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NHPBOKKD_03411 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NHPBOKKD_03412 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NHPBOKKD_03413 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NHPBOKKD_03415 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NHPBOKKD_03416 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NHPBOKKD_03417 2.4e-169 bsn L Ribonuclease
NHPBOKKD_03418 1.2e-205 msmX P Belongs to the ABC transporter superfamily
NHPBOKKD_03419 1.1e-135 yurK K UTRA
NHPBOKKD_03420 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NHPBOKKD_03421 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
NHPBOKKD_03422 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
NHPBOKKD_03423 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NHPBOKKD_03424 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NHPBOKKD_03425 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NHPBOKKD_03426 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NHPBOKKD_03428 1e-41
NHPBOKKD_03429 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPBOKKD_03430 3.5e-271 sufB O FeS cluster assembly
NHPBOKKD_03431 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NHPBOKKD_03432 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NHPBOKKD_03433 1.4e-245 sufD O assembly protein SufD
NHPBOKKD_03434 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NHPBOKKD_03435 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NHPBOKKD_03436 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
NHPBOKKD_03437 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NHPBOKKD_03438 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NHPBOKKD_03439 2.4e-56 yusD S SCP-2 sterol transfer family
NHPBOKKD_03440 5.6e-55 traF CO Thioredoxin
NHPBOKKD_03441 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NHPBOKKD_03442 1.1e-39 yusG S Protein of unknown function (DUF2553)
NHPBOKKD_03443 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NHPBOKKD_03444 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NHPBOKKD_03445 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NHPBOKKD_03446 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
NHPBOKKD_03447 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NHPBOKKD_03448 4.7e-09 S YuzL-like protein
NHPBOKKD_03449 2.2e-165 fadM E Proline dehydrogenase
NHPBOKKD_03450 5.1e-40
NHPBOKKD_03451 3.2e-53 yusN M Coat F domain
NHPBOKKD_03452 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
NHPBOKKD_03453 3.8e-293 yusP P Major facilitator superfamily
NHPBOKKD_03454 8.4e-66 yusQ S Tautomerase enzyme
NHPBOKKD_03455 1e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_03456 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_03457 2.7e-160 yusT K LysR substrate binding domain
NHPBOKKD_03458 3.8e-47 yusU S Protein of unknown function (DUF2573)
NHPBOKKD_03459 1e-153 yusV 3.6.3.34 HP ABC transporter
NHPBOKKD_03460 5.6e-66 S YusW-like protein
NHPBOKKD_03461 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
NHPBOKKD_03462 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
NHPBOKKD_03463 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_03464 1.2e-79 dps P Ferritin-like domain
NHPBOKKD_03465 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHPBOKKD_03466 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_03467 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
NHPBOKKD_03468 4.3e-158 yuxN K Transcriptional regulator
NHPBOKKD_03469 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NHPBOKKD_03470 2.3e-24 S Protein of unknown function (DUF3970)
NHPBOKKD_03471 2.2e-247 gerAA EG Spore germination protein
NHPBOKKD_03472 9.1e-198 gerAB E Spore germination protein
NHPBOKKD_03473 3.7e-91 gerAC S Spore germination B3/ GerAC like, C-terminal
NHPBOKKD_03474 1.1e-50 gerAC S Spore germination B3/ GerAC like, C-terminal
NHPBOKKD_03475 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPBOKKD_03476 5.5e-187 vraS 2.7.13.3 T Histidine kinase
NHPBOKKD_03477 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NHPBOKKD_03478 9.3e-129 liaG S Putative adhesin
NHPBOKKD_03479 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NHPBOKKD_03480 5.6e-62 liaI S membrane
NHPBOKKD_03481 4.8e-227 yvqJ EGP Major facilitator Superfamily
NHPBOKKD_03482 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
NHPBOKKD_03483 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NHPBOKKD_03484 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_03485 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NHPBOKKD_03486 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_03487 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NHPBOKKD_03488 0.0 T PhoQ Sensor
NHPBOKKD_03489 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_03490 3.6e-22
NHPBOKKD_03491 1.8e-96 yvrI K RNA polymerase
NHPBOKKD_03492 2.4e-19 S YvrJ protein family
NHPBOKKD_03493 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
NHPBOKKD_03494 1.3e-64 yvrL S Regulatory protein YrvL
NHPBOKKD_03495 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NHPBOKKD_03496 7.1e-124 macB V ABC transporter, ATP-binding protein
NHPBOKKD_03497 4.8e-176 M Efflux transporter rnd family, mfp subunit
NHPBOKKD_03498 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NHPBOKKD_03499 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_03500 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NHPBOKKD_03501 2.1e-179 fhuD P ABC transporter
NHPBOKKD_03503 2.6e-237 yvsH E Arginine ornithine antiporter
NHPBOKKD_03504 6.5e-16 S Small spore protein J (Spore_SspJ)
NHPBOKKD_03505 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NHPBOKKD_03506 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NHPBOKKD_03507 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NHPBOKKD_03508 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NHPBOKKD_03509 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
NHPBOKKD_03510 9.1e-158 yvgN S reductase
NHPBOKKD_03511 5.4e-86 yvgO
NHPBOKKD_03512 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NHPBOKKD_03513 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NHPBOKKD_03514 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NHPBOKKD_03515 0.0 helD 3.6.4.12 L DNA helicase
NHPBOKKD_03516 4.1e-107 yvgT S membrane
NHPBOKKD_03517 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NHPBOKKD_03518 1.6e-104 bdbD O Thioredoxin
NHPBOKKD_03519 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NHPBOKKD_03520 0.0 copA 3.6.3.54 P P-type ATPase
NHPBOKKD_03521 1.5e-29 copZ P Copper resistance protein CopZ
NHPBOKKD_03522 2.2e-48 csoR S transcriptional
NHPBOKKD_03523 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
NHPBOKKD_03524 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NHPBOKKD_03525 0.0 yvaC S Fusaric acid resistance protein-like
NHPBOKKD_03526 5.7e-73 yvaD S Family of unknown function (DUF5360)
NHPBOKKD_03527 2.8e-55 yvaE P Small Multidrug Resistance protein
NHPBOKKD_03528 4.1e-101 K Bacterial regulatory proteins, tetR family
NHPBOKKD_03529 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_03531 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NHPBOKKD_03532 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NHPBOKKD_03533 5.6e-143 est 3.1.1.1 S Carboxylesterase
NHPBOKKD_03534 2.4e-23 secG U Preprotein translocase subunit SecG
NHPBOKKD_03535 3.7e-153 yvaM S Serine aminopeptidase, S33
NHPBOKKD_03536 7.5e-36 yvzC K Transcriptional
NHPBOKKD_03537 4e-69 K transcriptional
NHPBOKKD_03538 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
NHPBOKKD_03539 2.2e-54 yodB K transcriptional
NHPBOKKD_03540 4.2e-226 NT chemotaxis protein
NHPBOKKD_03541 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NHPBOKKD_03542 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHPBOKKD_03543 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NHPBOKKD_03544 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHPBOKKD_03545 8.7e-61 yvbF K Belongs to the GbsR family
NHPBOKKD_03546 7.9e-13 S Sporulation delaying protein SdpA
NHPBOKKD_03547 7.6e-172
NHPBOKKD_03548 4.4e-08
NHPBOKKD_03549 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NHPBOKKD_03550 4.5e-45 sdpR K transcriptional
NHPBOKKD_03551 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NHPBOKKD_03552 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NHPBOKKD_03553 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NHPBOKKD_03554 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NHPBOKKD_03555 1.4e-98 yvbF K Belongs to the GbsR family
NHPBOKKD_03556 6.4e-103 yvbG U UPF0056 membrane protein
NHPBOKKD_03557 8.6e-113 yvbH S YvbH-like oligomerisation region
NHPBOKKD_03558 4.2e-124 exoY M Membrane
NHPBOKKD_03559 0.0 tcaA S response to antibiotic
NHPBOKKD_03560 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
NHPBOKKD_03561 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NHPBOKKD_03562 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NHPBOKKD_03563 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NHPBOKKD_03564 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NHPBOKKD_03565 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NHPBOKKD_03566 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NHPBOKKD_03567 1.6e-252 araE EGP Major facilitator Superfamily
NHPBOKKD_03568 5.5e-203 araR K transcriptional
NHPBOKKD_03569 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPBOKKD_03570 3.9e-159 yvbU K Transcriptional regulator
NHPBOKKD_03571 8.5e-157 yvbV EG EamA-like transporter family
NHPBOKKD_03572 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NHPBOKKD_03573 4.3e-197 yvbX S Glycosyl hydrolase
NHPBOKKD_03574 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NHPBOKKD_03575 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NHPBOKKD_03576 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NHPBOKKD_03577 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPBOKKD_03578 8.9e-201 desK 2.7.13.3 T Histidine kinase
NHPBOKKD_03579 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
NHPBOKKD_03580 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NHPBOKKD_03581 2.6e-157 rsbQ S Alpha/beta hydrolase family
NHPBOKKD_03582 1.4e-199 rsbU 3.1.3.3 T response regulator
NHPBOKKD_03583 2.6e-252 galA 3.2.1.89 G arabinogalactan
NHPBOKKD_03584 0.0 lacA 3.2.1.23 G beta-galactosidase
NHPBOKKD_03585 3.2e-150 ganQ P transport
NHPBOKKD_03586 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
NHPBOKKD_03587 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
NHPBOKKD_03588 1.8e-184 lacR K Transcriptional regulator
NHPBOKKD_03589 6.6e-111 yvfI K COG2186 Transcriptional regulators
NHPBOKKD_03590 1.4e-309 yvfH C L-lactate permease
NHPBOKKD_03591 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NHPBOKKD_03592 1e-31 yvfG S YvfG protein
NHPBOKKD_03593 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
NHPBOKKD_03594 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NHPBOKKD_03595 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NHPBOKKD_03596 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NHPBOKKD_03597 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPBOKKD_03598 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPBOKKD_03599 3.6e-207 epsI GM pyruvyl transferase
NHPBOKKD_03600 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
NHPBOKKD_03601 4.8e-207 epsG S EpsG family
NHPBOKKD_03602 5.3e-220 epsF GT4 M Glycosyl transferases group 1
NHPBOKKD_03603 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NHPBOKKD_03604 2e-224 epsD GT4 M Glycosyl transferase 4-like
NHPBOKKD_03605 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NHPBOKKD_03606 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NHPBOKKD_03607 4e-122 ywqC M biosynthesis protein
NHPBOKKD_03608 5.7e-77 slr K transcriptional
NHPBOKKD_03609 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NHPBOKKD_03611 4.6e-93 padC Q Phenolic acid decarboxylase
NHPBOKKD_03612 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
NHPBOKKD_03613 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NHPBOKKD_03614 9.6e-266 pbpE V Beta-lactamase
NHPBOKKD_03615 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NHPBOKKD_03616 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NHPBOKKD_03617 1.8e-295 yveA E amino acid
NHPBOKKD_03618 2.6e-106 yvdT K Transcriptional regulator
NHPBOKKD_03619 6.7e-51 ykkC P Small Multidrug Resistance protein
NHPBOKKD_03620 4.1e-50 sugE P Small Multidrug Resistance protein
NHPBOKKD_03621 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
NHPBOKKD_03622 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
NHPBOKKD_03623 1.5e-183 S Patatin-like phospholipase
NHPBOKKD_03625 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NHPBOKKD_03626 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NHPBOKKD_03627 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NHPBOKKD_03628 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NHPBOKKD_03629 1.2e-158 malA S Protein of unknown function (DUF1189)
NHPBOKKD_03630 7.8e-149 malD P transport
NHPBOKKD_03631 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
NHPBOKKD_03632 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NHPBOKKD_03633 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NHPBOKKD_03634 3.6e-174 yvdE K Transcriptional regulator
NHPBOKKD_03635 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
NHPBOKKD_03636 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
NHPBOKKD_03637 4.2e-126 catB 2.3.1.28 V Chloramphenicol acetyltransferase
NHPBOKKD_03638 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NHPBOKKD_03639 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NHPBOKKD_03640 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NHPBOKKD_03641 0.0 yxdM V ABC transporter (permease)
NHPBOKKD_03642 5.6e-141 yvcR V ABC transporter, ATP-binding protein
NHPBOKKD_03643 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NHPBOKKD_03644 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_03645 1.8e-33
NHPBOKKD_03646 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NHPBOKKD_03647 1.6e-36 crh G Phosphocarrier protein Chr
NHPBOKKD_03648 1.4e-170 whiA K May be required for sporulation
NHPBOKKD_03649 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NHPBOKKD_03650 5.7e-166 rapZ S Displays ATPase and GTPase activities
NHPBOKKD_03651 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NHPBOKKD_03652 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NHPBOKKD_03653 1.4e-102 usp CBM50 M protein conserved in bacteria
NHPBOKKD_03654 2.4e-278 S COG0457 FOG TPR repeat
NHPBOKKD_03655 0.0 msbA2 3.6.3.44 V ABC transporter
NHPBOKKD_03657 0.0
NHPBOKKD_03658 4.6e-121
NHPBOKKD_03659 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NHPBOKKD_03660 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NHPBOKKD_03661 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NHPBOKKD_03662 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NHPBOKKD_03663 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NHPBOKKD_03664 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NHPBOKKD_03665 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NHPBOKKD_03666 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NHPBOKKD_03667 4.5e-140 yvpB NU protein conserved in bacteria
NHPBOKKD_03668 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NHPBOKKD_03669 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NHPBOKKD_03670 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NHPBOKKD_03671 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
NHPBOKKD_03672 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NHPBOKKD_03673 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NHPBOKKD_03674 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NHPBOKKD_03675 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NHPBOKKD_03676 3.6e-134 yvoA K transcriptional
NHPBOKKD_03677 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NHPBOKKD_03678 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_03679 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
NHPBOKKD_03680 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
NHPBOKKD_03681 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_03682 2.7e-203 yvmA EGP Major facilitator Superfamily
NHPBOKKD_03683 1.2e-50 yvlD S Membrane
NHPBOKKD_03684 2.6e-26 pspB KT PspC domain
NHPBOKKD_03685 3.4e-168 yvlB S Putative adhesin
NHPBOKKD_03686 8e-49 yvlA
NHPBOKKD_03687 6.7e-34 yvkN
NHPBOKKD_03688 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NHPBOKKD_03689 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NHPBOKKD_03690 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NHPBOKKD_03691 1.2e-30 csbA S protein conserved in bacteria
NHPBOKKD_03692 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NHPBOKKD_03693 7e-101 yvkB K Transcriptional regulator
NHPBOKKD_03694 7.9e-228 yvkA EGP Major facilitator Superfamily
NHPBOKKD_03695 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHPBOKKD_03696 1e-54 swrA S Swarming motility protein
NHPBOKKD_03697 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NHPBOKKD_03698 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NHPBOKKD_03699 1.6e-123 ftsE D cell division ATP-binding protein FtsE
NHPBOKKD_03700 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
NHPBOKKD_03701 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NHPBOKKD_03702 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NHPBOKKD_03703 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NHPBOKKD_03704 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NHPBOKKD_03705 2.8e-66
NHPBOKKD_03706 1.9e-08 fliT S bacterial-type flagellum organization
NHPBOKKD_03707 2.9e-69 fliS N flagellar protein FliS
NHPBOKKD_03708 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NHPBOKKD_03709 6.1e-57 flaG N flagellar protein FlaG
NHPBOKKD_03710 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NHPBOKKD_03711 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NHPBOKKD_03712 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NHPBOKKD_03713 2.6e-50 yviE
NHPBOKKD_03714 1.1e-156 flgL N Belongs to the bacterial flagellin family
NHPBOKKD_03715 1.2e-264 flgK N flagellar hook-associated protein
NHPBOKKD_03716 2.4e-78 flgN NOU FlgN protein
NHPBOKKD_03717 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
NHPBOKKD_03718 7e-74 yvyF S flagellar protein
NHPBOKKD_03719 2.7e-129 comFC S Phosphoribosyl transferase domain
NHPBOKKD_03720 5.7e-46 comFB S Late competence development protein ComFB
NHPBOKKD_03721 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NHPBOKKD_03722 7.3e-155 degV S protein conserved in bacteria
NHPBOKKD_03723 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NHPBOKKD_03724 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NHPBOKKD_03725 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NHPBOKKD_03726 6e-163 yvhJ K Transcriptional regulator
NHPBOKKD_03727 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NHPBOKKD_03728 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NHPBOKKD_03729 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
NHPBOKKD_03730 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
NHPBOKKD_03731 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
NHPBOKKD_03732 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHPBOKKD_03733 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NHPBOKKD_03734 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NHPBOKKD_03735 2.7e-78 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NHPBOKKD_03736 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NHPBOKKD_03737 0.0 lytB 3.5.1.28 D Stage II sporulation protein
NHPBOKKD_03738 6e-38
NHPBOKKD_03739 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
NHPBOKKD_03740 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NHPBOKKD_03741 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHPBOKKD_03742 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NHPBOKKD_03743 8.1e-257 ggaA M Glycosyltransferase like family 2
NHPBOKKD_03745 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NHPBOKKD_03746 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NHPBOKKD_03747 1.1e-150 tagG GM Transport permease protein
NHPBOKKD_03748 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NHPBOKKD_03749 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
NHPBOKKD_03750 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NHPBOKKD_03751 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NHPBOKKD_03752 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NHPBOKKD_03753 1.2e-260
NHPBOKKD_03754 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NHPBOKKD_03755 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NHPBOKKD_03756 3.5e-266 gerBA EG Spore germination protein
NHPBOKKD_03757 7.5e-200 gerBB E Spore germination protein
NHPBOKKD_03758 7.6e-216 gerAC S Spore germination protein
NHPBOKKD_03759 1.9e-248 ywtG EGP Major facilitator Superfamily
NHPBOKKD_03760 8.4e-171 ywtF K Transcriptional regulator
NHPBOKKD_03761 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NHPBOKKD_03762 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NHPBOKKD_03763 3.6e-21 ywtC
NHPBOKKD_03764 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NHPBOKKD_03765 8.6e-70 pgsC S biosynthesis protein
NHPBOKKD_03766 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NHPBOKKD_03767 1.5e-180 rbsR K transcriptional
NHPBOKKD_03768 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NHPBOKKD_03769 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NHPBOKKD_03770 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NHPBOKKD_03771 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NHPBOKKD_03772 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NHPBOKKD_03773 4.6e-94 batE T Sh3 type 3 domain protein
NHPBOKKD_03774 3.6e-48 ywsA S Protein of unknown function (DUF3892)
NHPBOKKD_03775 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NHPBOKKD_03776 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NHPBOKKD_03777 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NHPBOKKD_03778 1.1e-169 alsR K LysR substrate binding domain
NHPBOKKD_03779 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NHPBOKKD_03780 7.5e-126 ywrJ
NHPBOKKD_03781 7.6e-131 cotB
NHPBOKKD_03782 1.2e-210 cotH M Spore Coat
NHPBOKKD_03783 3e-12
NHPBOKKD_03784 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NHPBOKKD_03785 2.9e-54 S Domain of unknown function (DUF4181)
NHPBOKKD_03786 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NHPBOKKD_03787 2.1e-82 ywrC K Transcriptional regulator
NHPBOKKD_03788 2.4e-104 ywrB P Chromate transporter
NHPBOKKD_03789 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
NHPBOKKD_03791 2.7e-102 ywqN S NAD(P)H-dependent
NHPBOKKD_03792 2.9e-162 K Transcriptional regulator
NHPBOKKD_03793 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NHPBOKKD_03794 1.7e-52 S MORN repeat variant
NHPBOKKD_03795 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
NHPBOKKD_03796 1.3e-38 ywqI S Family of unknown function (DUF5344)
NHPBOKKD_03797 3.3e-15 S Domain of unknown function (DUF5082)
NHPBOKKD_03798 3.4e-154 ywqG S Domain of unknown function (DUF1963)
NHPBOKKD_03799 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NHPBOKKD_03800 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NHPBOKKD_03801 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NHPBOKKD_03802 2e-116 ywqC M biosynthesis protein
NHPBOKKD_03803 1.2e-17
NHPBOKKD_03804 3.8e-309 ywqB S SWIM zinc finger
NHPBOKKD_03805 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NHPBOKKD_03806 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NHPBOKKD_03807 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NHPBOKKD_03808 9.8e-58 ssbB L Single-stranded DNA-binding protein
NHPBOKKD_03809 1.3e-66 ywpG
NHPBOKKD_03810 1.1e-66 ywpF S YwpF-like protein
NHPBOKKD_03811 8e-51 srtA 3.4.22.70 M Sortase family
NHPBOKKD_03812 1.9e-153 ywpD T Histidine kinase
NHPBOKKD_03813 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NHPBOKKD_03814 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NHPBOKKD_03815 2.1e-199 S aspartate phosphatase
NHPBOKKD_03816 1.5e-141 flhP N flagellar basal body
NHPBOKKD_03817 6.9e-126 flhO N flagellar basal body
NHPBOKKD_03818 3.5e-180 mbl D Rod shape-determining protein
NHPBOKKD_03819 3e-44 spoIIID K Stage III sporulation protein D
NHPBOKKD_03820 2.1e-70 ywoH K COG1846 Transcriptional regulators
NHPBOKKD_03821 2.7e-211 ywoG EGP Major facilitator Superfamily
NHPBOKKD_03822 1.2e-231 ywoF P Right handed beta helix region
NHPBOKKD_03823 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NHPBOKKD_03824 4.4e-242 ywoD EGP Major facilitator superfamily
NHPBOKKD_03825 4e-104 phzA Q Isochorismatase family
NHPBOKKD_03826 1.2e-77
NHPBOKKD_03827 2.5e-225 amt P Ammonium transporter
NHPBOKKD_03828 1.6e-58 nrgB K Belongs to the P(II) protein family
NHPBOKKD_03829 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NHPBOKKD_03830 1.6e-81 S KNTase C-terminal domain
NHPBOKKD_03831 7.3e-144 mta K transcriptional
NHPBOKKD_03832 2.6e-59 ywnC S Family of unknown function (DUF5362)
NHPBOKKD_03833 1.6e-114 ywnB S NAD(P)H-binding
NHPBOKKD_03834 1.7e-64 ywnA K Transcriptional regulator
NHPBOKKD_03835 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NHPBOKKD_03836 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NHPBOKKD_03837 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NHPBOKKD_03839 3.8e-11 csbD K CsbD-like
NHPBOKKD_03840 3e-84 ywmF S Peptidase M50
NHPBOKKD_03841 1.3e-103 S response regulator aspartate phosphatase
NHPBOKKD_03842 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NHPBOKKD_03843 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NHPBOKKD_03845 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NHPBOKKD_03846 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NHPBOKKD_03847 2e-178 spoIID D Stage II sporulation protein D
NHPBOKKD_03848 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHPBOKKD_03849 1.6e-134 ywmB S TATA-box binding
NHPBOKKD_03850 1.3e-32 ywzB S membrane
NHPBOKKD_03851 4.3e-88 ywmA
NHPBOKKD_03852 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NHPBOKKD_03853 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NHPBOKKD_03854 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NHPBOKKD_03855 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NHPBOKKD_03856 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHPBOKKD_03857 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NHPBOKKD_03858 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NHPBOKKD_03859 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NHPBOKKD_03860 2.5e-62 atpI S ATP synthase
NHPBOKKD_03861 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NHPBOKKD_03862 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NHPBOKKD_03863 7.2e-95 ywlG S Belongs to the UPF0340 family
NHPBOKKD_03864 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NHPBOKKD_03865 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NHPBOKKD_03866 1.7e-91 mntP P Probably functions as a manganese efflux pump
NHPBOKKD_03867 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NHPBOKKD_03868 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NHPBOKKD_03869 6.1e-112 spoIIR S stage II sporulation protein R
NHPBOKKD_03870 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
NHPBOKKD_03872 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NHPBOKKD_03873 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NHPBOKKD_03874 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPBOKKD_03875 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NHPBOKKD_03876 8.6e-160 ywkB S Membrane transport protein
NHPBOKKD_03877 0.0 sfcA 1.1.1.38 C malic enzyme
NHPBOKKD_03878 2.4e-104 tdk 2.7.1.21 F thymidine kinase
NHPBOKKD_03879 1.1e-32 rpmE J Binds the 23S rRNA
NHPBOKKD_03880 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NHPBOKKD_03881 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NHPBOKKD_03882 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NHPBOKKD_03883 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NHPBOKKD_03884 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NHPBOKKD_03885 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NHPBOKKD_03886 2.4e-92 ywjG S Domain of unknown function (DUF2529)
NHPBOKKD_03887 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NHPBOKKD_03888 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NHPBOKKD_03889 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NHPBOKKD_03890 0.0 fadF C COG0247 Fe-S oxidoreductase
NHPBOKKD_03891 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NHPBOKKD_03892 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NHPBOKKD_03893 2.7e-42 ywjC
NHPBOKKD_03894 4.8e-96 ywjB H RibD C-terminal domain
NHPBOKKD_03895 0.0 ywjA V ABC transporter
NHPBOKKD_03896 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NHPBOKKD_03897 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
NHPBOKKD_03898 2.4e-98 narJ 1.7.5.1 C nitrate reductase
NHPBOKKD_03899 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
NHPBOKKD_03900 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHPBOKKD_03901 7e-86 arfM T cyclic nucleotide binding
NHPBOKKD_03902 4.3e-140 ywiC S YwiC-like protein
NHPBOKKD_03903 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
NHPBOKKD_03904 9.8e-214 narK P COG2223 Nitrate nitrite transporter
NHPBOKKD_03905 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NHPBOKKD_03906 4.7e-73 ywiB S protein conserved in bacteria
NHPBOKKD_03907 1e-07 S Bacteriocin subtilosin A
NHPBOKKD_03908 2.6e-271 C Fe-S oxidoreductases
NHPBOKKD_03910 3.3e-132 cbiO V ABC transporter
NHPBOKKD_03911 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NHPBOKKD_03912 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
NHPBOKKD_03913 1.2e-249 L Peptidase, M16
NHPBOKKD_03915 2.9e-249 ywhL CO amine dehydrogenase activity
NHPBOKKD_03916 2.5e-205 ywhK CO amine dehydrogenase activity
NHPBOKKD_03917 2.3e-79 S aspartate phosphatase
NHPBOKKD_03919 1e-84 ywhH S Aminoacyl-tRNA editing domain
NHPBOKKD_03920 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NHPBOKKD_03921 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NHPBOKKD_03922 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NHPBOKKD_03923 5.2e-95 ywhD S YwhD family
NHPBOKKD_03924 5.1e-119 ywhC S Peptidase family M50
NHPBOKKD_03925 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NHPBOKKD_03926 3.3e-71 ywhA K Transcriptional regulator
NHPBOKKD_03927 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NHPBOKKD_03929 2.6e-242 mmr U Major Facilitator Superfamily
NHPBOKKD_03930 2.8e-79 yffB K Transcriptional regulator
NHPBOKKD_03931 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NHPBOKKD_03932 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
NHPBOKKD_03933 3.1e-36 ywzC S Belongs to the UPF0741 family
NHPBOKKD_03934 1.6e-111 rsfA_1
NHPBOKKD_03935 5.2e-159 ywfM EG EamA-like transporter family
NHPBOKKD_03936 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NHPBOKKD_03937 9.2e-164 cysL K Transcriptional regulator
NHPBOKKD_03938 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NHPBOKKD_03939 1.1e-146 ywfI C May function as heme-dependent peroxidase
NHPBOKKD_03940 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
NHPBOKKD_03941 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
NHPBOKKD_03942 2.9e-210 bacE EGP Major facilitator Superfamily
NHPBOKKD_03943 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NHPBOKKD_03944 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NHPBOKKD_03945 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NHPBOKKD_03946 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NHPBOKKD_03947 4.6e-206 ywfA EGP Major facilitator Superfamily
NHPBOKKD_03948 5.1e-251 lysP E amino acid
NHPBOKKD_03949 0.0 rocB E arginine degradation protein
NHPBOKKD_03950 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NHPBOKKD_03951 3.7e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NHPBOKKD_03952 1.8e-78
NHPBOKKD_03953 3.5e-87 spsL 5.1.3.13 M Spore Coat
NHPBOKKD_03954 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NHPBOKKD_03955 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NHPBOKKD_03956 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NHPBOKKD_03957 1.7e-190 spsG M Spore Coat
NHPBOKKD_03958 9.7e-132 spsF M Spore Coat
NHPBOKKD_03959 3.2e-214 spsE 2.5.1.56 M acid synthase
NHPBOKKD_03960 4e-164 spsD 2.3.1.210 K Spore Coat
NHPBOKKD_03961 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
NHPBOKKD_03962 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
NHPBOKKD_03963 2.8e-145 spsA M Spore Coat
NHPBOKKD_03964 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NHPBOKKD_03965 4.3e-59 ywdK S small membrane protein
NHPBOKKD_03966 1.3e-238 ywdJ F Xanthine uracil
NHPBOKKD_03967 7.7e-49 ywdI S Family of unknown function (DUF5327)
NHPBOKKD_03968 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NHPBOKKD_03969 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NHPBOKKD_03970 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
NHPBOKKD_03972 1.4e-113 ywdD
NHPBOKKD_03973 1.3e-57 pex K Transcriptional regulator PadR-like family
NHPBOKKD_03974 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NHPBOKKD_03975 2e-28 ywdA
NHPBOKKD_03976 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NHPBOKKD_03977 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPBOKKD_03978 1e-139 focA P Formate/nitrite transporter
NHPBOKKD_03979 2.4e-150 sacT K transcriptional antiterminator
NHPBOKKD_03981 0.0 vpr O Belongs to the peptidase S8 family
NHPBOKKD_03982 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPBOKKD_03983 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NHPBOKKD_03984 2.9e-202 rodA D Belongs to the SEDS family
NHPBOKKD_03985 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NHPBOKKD_03986 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NHPBOKKD_03987 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NHPBOKKD_03988 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NHPBOKKD_03989 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NHPBOKKD_03990 1e-35 ywzA S membrane
NHPBOKKD_03991 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NHPBOKKD_03992 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NHPBOKKD_03993 9.5e-60 gtcA S GtrA-like protein
NHPBOKKD_03994 2.2e-122 ywcC K transcriptional regulator
NHPBOKKD_03996 9.8e-49 ywcB S Protein of unknown function, DUF485
NHPBOKKD_03997 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NHPBOKKD_03998 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NHPBOKKD_03999 2.6e-225 ywbN P Dyp-type peroxidase family protein
NHPBOKKD_04000 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
NHPBOKKD_04001 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
NHPBOKKD_04002 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NHPBOKKD_04003 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NHPBOKKD_04004 4.3e-153 ywbI K Transcriptional regulator
NHPBOKKD_04005 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NHPBOKKD_04006 2.3e-111 ywbG M effector of murein hydrolase
NHPBOKKD_04007 1.9e-209 ywbF EGP Major facilitator Superfamily
NHPBOKKD_04008 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
NHPBOKKD_04009 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
NHPBOKKD_04010 4.4e-67 ywbC 4.4.1.5 E glyoxalase
NHPBOKKD_04011 1.8e-127 ywbB S Protein of unknown function (DUF2711)
NHPBOKKD_04012 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHPBOKKD_04013 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
NHPBOKKD_04014 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPBOKKD_04015 4e-153 sacY K transcriptional antiterminator
NHPBOKKD_04016 7e-169 gspA M General stress
NHPBOKKD_04017 1.7e-128 ywaF S Integral membrane protein
NHPBOKKD_04018 8.1e-88 ywaE K Transcriptional regulator
NHPBOKKD_04019 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NHPBOKKD_04020 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NHPBOKKD_04021 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NHPBOKKD_04022 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NHPBOKKD_04023 5e-14 S D-Ala-teichoic acid biosynthesis protein
NHPBOKKD_04024 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_04025 1.2e-232 dltB M membrane protein involved in D-alanine export
NHPBOKKD_04026 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NHPBOKKD_04027 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NHPBOKKD_04028 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_04029 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NHPBOKKD_04030 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NHPBOKKD_04031 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NHPBOKKD_04032 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NHPBOKKD_04033 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NHPBOKKD_04034 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NHPBOKKD_04035 1.1e-19 yxzF
NHPBOKKD_04036 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NHPBOKKD_04037 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NHPBOKKD_04038 2.1e-216 yxlH EGP Major facilitator Superfamily
NHPBOKKD_04039 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NHPBOKKD_04040 5.1e-167 yxlF V ABC transporter, ATP-binding protein
NHPBOKKD_04041 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
NHPBOKKD_04042 1.2e-31
NHPBOKKD_04043 3.9e-48 yxlC S Family of unknown function (DUF5345)
NHPBOKKD_04044 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NHPBOKKD_04045 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NHPBOKKD_04046 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NHPBOKKD_04047 0.0 cydD V ATP-binding protein
NHPBOKKD_04048 0.0 cydD V ATP-binding
NHPBOKKD_04049 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NHPBOKKD_04050 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
NHPBOKKD_04051 1.5e-229 cimH C COG3493 Na citrate symporter
NHPBOKKD_04052 0.0 3.4.24.84 O Peptidase family M48
NHPBOKKD_04054 3e-156 yxkH G Polysaccharide deacetylase
NHPBOKKD_04055 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NHPBOKKD_04056 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
NHPBOKKD_04057 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPBOKKD_04058 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NHPBOKKD_04059 4.1e-73 yxkC S Domain of unknown function (DUF4352)
NHPBOKKD_04060 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NHPBOKKD_04061 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
NHPBOKKD_04062 1.9e-166 yxjO K LysR substrate binding domain
NHPBOKKD_04063 2.4e-78 S Protein of unknown function (DUF1453)
NHPBOKKD_04064 1.5e-193 yxjM T Signal transduction histidine kinase
NHPBOKKD_04065 8.9e-116 K helix_turn_helix, Lux Regulon
NHPBOKKD_04066 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NHPBOKKD_04069 1e-87 yxjI S LURP-one-related
NHPBOKKD_04070 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
NHPBOKKD_04071 1e-220 yxjG 2.1.1.14 E Methionine synthase
NHPBOKKD_04072 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NHPBOKKD_04073 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NHPBOKKD_04074 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NHPBOKKD_04075 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
NHPBOKKD_04076 3.1e-161 rlmA 2.1.1.187 Q Methyltransferase domain
NHPBOKKD_04077 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHPBOKKD_04078 1.2e-22 T Domain of unknown function (DUF4163)
NHPBOKKD_04079 2.7e-48 yxiS
NHPBOKKD_04080 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NHPBOKKD_04081 6.6e-224 citH C Citrate transporter
NHPBOKKD_04082 5e-144 exoK GH16 M licheninase activity
NHPBOKKD_04083 8.3e-151 licT K transcriptional antiterminator
NHPBOKKD_04084 6.6e-114
NHPBOKKD_04085 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
NHPBOKKD_04086 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NHPBOKKD_04087 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NHPBOKKD_04090 1.6e-48 yxiJ S YxiJ-like protein
NHPBOKKD_04091 1.2e-96 yxiI S Protein of unknown function (DUF2716)
NHPBOKKD_04092 3.8e-81
NHPBOKKD_04093 4.9e-46
NHPBOKKD_04094 3.7e-75 yxiG
NHPBOKKD_04095 6.4e-63
NHPBOKKD_04096 1.7e-84
NHPBOKKD_04097 1.5e-71 yxxG
NHPBOKKD_04098 0.0 wapA M COG3209 Rhs family protein
NHPBOKKD_04099 1.9e-58 bsr 3.5.4.5 F Cytidine and deoxycytidylate deaminase zinc-binding region
NHPBOKKD_04100 2.9e-168 yxxF EG EamA-like transporter family
NHPBOKKD_04101 1.1e-72 yxiE T Belongs to the universal stress protein A family
NHPBOKKD_04102 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPBOKKD_04103 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NHPBOKKD_04104 3.6e-51
NHPBOKKD_04105 2.2e-78 S SMI1 / KNR4 family
NHPBOKKD_04106 0.0 S nuclease activity
NHPBOKKD_04107 3.6e-39 yxiC S Family of unknown function (DUF5344)
NHPBOKKD_04108 2.1e-21 S Domain of unknown function (DUF5082)
NHPBOKKD_04109 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NHPBOKKD_04110 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
NHPBOKKD_04111 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
NHPBOKKD_04112 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NHPBOKKD_04113 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
NHPBOKKD_04114 1.3e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
NHPBOKKD_04115 6.1e-252 lysP E amino acid
NHPBOKKD_04116 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NHPBOKKD_04117 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NHPBOKKD_04118 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NHPBOKKD_04119 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NHPBOKKD_04120 3e-153 yxxB S Domain of Unknown Function (DUF1206)
NHPBOKKD_04121 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
NHPBOKKD_04122 2e-255 yxeQ S MmgE/PrpD family
NHPBOKKD_04123 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
NHPBOKKD_04124 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NHPBOKKD_04125 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
NHPBOKKD_04126 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NHPBOKKD_04127 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NHPBOKKD_04128 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NHPBOKKD_04130 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NHPBOKKD_04131 6.2e-151 yidA S hydrolases of the HAD superfamily
NHPBOKKD_04134 1.3e-20 yxeE
NHPBOKKD_04135 1.9e-16 yxeD
NHPBOKKD_04136 8.5e-69
NHPBOKKD_04137 6e-177 fhuD P ABC transporter
NHPBOKKD_04138 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NHPBOKKD_04139 0.0 yxdM V ABC transporter (permease)
NHPBOKKD_04140 9.4e-141 yxdL V ABC transporter, ATP-binding protein
NHPBOKKD_04141 1.3e-182 T PhoQ Sensor
NHPBOKKD_04142 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_04143 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NHPBOKKD_04144 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NHPBOKKD_04145 2.3e-167 iolH G Xylose isomerase-like TIM barrel
NHPBOKKD_04146 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NHPBOKKD_04147 1.3e-235 iolF EGP Major facilitator Superfamily
NHPBOKKD_04148 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NHPBOKKD_04149 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NHPBOKKD_04150 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NHPBOKKD_04151 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NHPBOKKD_04152 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NHPBOKKD_04153 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NHPBOKKD_04154 3.7e-176 iolS C Aldo keto reductase
NHPBOKKD_04156 8.3e-48 yxcD S Protein of unknown function (DUF2653)
NHPBOKKD_04157 2.3e-246 csbC EGP Major facilitator Superfamily
NHPBOKKD_04158 0.0 htpG O Molecular chaperone. Has ATPase activity
NHPBOKKD_04160 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
NHPBOKKD_04161 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
NHPBOKKD_04162 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NHPBOKKD_04163 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
NHPBOKKD_04164 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
NHPBOKKD_04165 3.3e-127 yxbB Q Met-10+ like-protein
NHPBOKKD_04166 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
NHPBOKKD_04167 1.1e-86 yxnB
NHPBOKKD_04168 0.0 asnB 6.3.5.4 E Asparagine synthase
NHPBOKKD_04169 7.6e-214 yxaM U MFS_1 like family
NHPBOKKD_04170 6.8e-93 S PQQ-like domain
NHPBOKKD_04171 3.5e-65 S Family of unknown function (DUF5391)
NHPBOKKD_04172 1.1e-75 yxaI S membrane protein domain
NHPBOKKD_04173 1.4e-228 P Protein of unknown function (DUF418)
NHPBOKKD_04174 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
NHPBOKKD_04175 7.1e-101 yxaF K Transcriptional regulator
NHPBOKKD_04176 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NHPBOKKD_04177 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NHPBOKKD_04178 5.2e-50 S LrgA family
NHPBOKKD_04179 2.6e-118 yxaC M effector of murein hydrolase
NHPBOKKD_04180 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
NHPBOKKD_04181 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NHPBOKKD_04182 7.3e-127 gntR K transcriptional
NHPBOKKD_04183 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NHPBOKKD_04184 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
NHPBOKKD_04185 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NHPBOKKD_04186 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NHPBOKKD_04187 3.8e-287 ahpF O Alkyl hydroperoxide reductase
NHPBOKKD_04188 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NHPBOKKD_04189 2.5e-19 bglF G phosphotransferase system
NHPBOKKD_04190 1.3e-128 yydK K Transcriptional regulator
NHPBOKKD_04191 7.6e-13
NHPBOKKD_04192 3.3e-119 S ABC-2 family transporter protein
NHPBOKKD_04193 1.8e-110 prrC P ABC transporter
NHPBOKKD_04194 8.4e-134 yydH O Peptidase M50
NHPBOKKD_04195 7.7e-185 S Radical SAM superfamily
NHPBOKKD_04196 8e-12
NHPBOKKD_04197 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NHPBOKKD_04198 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
NHPBOKKD_04199 3.5e-65
NHPBOKKD_04200 7.3e-280 S Calcineurin-like phosphoesterase
NHPBOKKD_04201 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NHPBOKKD_04202 1.1e-09 S YyzF-like protein
NHPBOKKD_04203 4.2e-71
NHPBOKKD_04204 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NHPBOKKD_04206 2.1e-33 yycQ S Protein of unknown function (DUF2651)
NHPBOKKD_04207 1.6e-221 yycP
NHPBOKKD_04208 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NHPBOKKD_04209 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
NHPBOKKD_04210 5e-188 S aspartate phosphatase
NHPBOKKD_04212 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NHPBOKKD_04213 9.7e-261 rocE E amino acid
NHPBOKKD_04214 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NHPBOKKD_04215 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NHPBOKKD_04216 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NHPBOKKD_04217 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NHPBOKKD_04218 7.3e-155 yycI S protein conserved in bacteria
NHPBOKKD_04219 3.6e-260 yycH S protein conserved in bacteria
NHPBOKKD_04220 0.0 vicK 2.7.13.3 T Histidine kinase
NHPBOKKD_04221 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NHPBOKKD_04226 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NHPBOKKD_04227 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPBOKKD_04228 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NHPBOKKD_04229 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NHPBOKKD_04231 1.9e-15 yycC K YycC-like protein
NHPBOKKD_04232 8.4e-221 yeaN P COG2807 Cyanate permease
NHPBOKKD_04233 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NHPBOKKD_04234 2.2e-73 rplI J binds to the 23S rRNA
NHPBOKKD_04235 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NHPBOKKD_04236 2.9e-160 yybS S membrane
NHPBOKKD_04238 3.9e-84 cotF M Spore coat protein
NHPBOKKD_04239 1.4e-68 ydeP3 K Transcriptional regulator
NHPBOKKD_04240 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NHPBOKKD_04241 1.3e-70
NHPBOKKD_04243 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
NHPBOKKD_04244 1e-16
NHPBOKKD_04245 1.3e-78 yybN S Protein of unknown function (DUF2712)
NHPBOKKD_04246 4.1e-125
NHPBOKKD_04247 9e-122
NHPBOKKD_04248 2e-127 S Protein of unknown function (DUF2705)
NHPBOKKD_04249 2.6e-115 V ATPases associated with a variety of cellular activities
NHPBOKKD_04250 6.2e-132
NHPBOKKD_04251 5.9e-67 yybH S SnoaL-like domain
NHPBOKKD_04252 3e-124 yybG S Pentapeptide repeat-containing protein
NHPBOKKD_04253 3.2e-220 ynfM EGP Major facilitator Superfamily
NHPBOKKD_04254 2.1e-165 yybE K Transcriptional regulator
NHPBOKKD_04255 2e-79 yjcF S Acetyltransferase (GNAT) domain
NHPBOKKD_04256 2.7e-77 yybC
NHPBOKKD_04257 3e-127 S Metallo-beta-lactamase superfamily
NHPBOKKD_04258 5.6e-77 yybA 2.3.1.57 K transcriptional
NHPBOKKD_04259 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
NHPBOKKD_04260 1.5e-101 yyaS S Membrane
NHPBOKKD_04261 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
NHPBOKKD_04262 5.4e-67 yyaQ S YjbR
NHPBOKKD_04263 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
NHPBOKKD_04264 1.7e-249 tetL EGP Major facilitator Superfamily
NHPBOKKD_04265 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
NHPBOKKD_04266 5.1e-61 yyaN K MerR HTH family regulatory protein
NHPBOKKD_04267 3.3e-161 yyaM EG EamA-like transporter family
NHPBOKKD_04268 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NHPBOKKD_04269 9.5e-169 yyaK S CAAX protease self-immunity
NHPBOKKD_04270 3.8e-246 EGP Major facilitator superfamily
NHPBOKKD_04271 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NHPBOKKD_04272 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NHPBOKKD_04273 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NHPBOKKD_04274 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
NHPBOKKD_04275 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NHPBOKKD_04276 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NHPBOKKD_04277 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NHPBOKKD_04278 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NHPBOKKD_04279 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NHPBOKKD_04280 2.3e-33 yyzM S protein conserved in bacteria
NHPBOKKD_04281 8.1e-177 yyaD S Membrane
NHPBOKKD_04282 1.6e-111 yyaC S Sporulation protein YyaC
NHPBOKKD_04283 2.1e-149 spo0J K Belongs to the ParB family
NHPBOKKD_04284 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NHPBOKKD_04285 1.5e-74 S Bacterial PH domain
NHPBOKKD_04286 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NHPBOKKD_04287 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NHPBOKKD_04288 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NHPBOKKD_04289 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NHPBOKKD_04290 6.5e-108 jag S single-stranded nucleic acid binding R3H
NHPBOKKD_04291 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NHPBOKKD_04292 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)