ORF_ID e_value Gene_name EC_number CAZy COGs Description
OLHBHBLE_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OLHBHBLE_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OLHBHBLE_00003 2.4e-33 yaaA S S4 domain
OLHBHBLE_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OLHBHBLE_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
OLHBHBLE_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OLHBHBLE_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OLHBHBLE_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00011 2.7e-182 yaaC S YaaC-like Protein
OLHBHBLE_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OLHBHBLE_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OLHBHBLE_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OLHBHBLE_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OLHBHBLE_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OLHBHBLE_00017 1.3e-09
OLHBHBLE_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OLHBHBLE_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OLHBHBLE_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
OLHBHBLE_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
OLHBHBLE_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OLHBHBLE_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OLHBHBLE_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OLHBHBLE_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OLHBHBLE_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
OLHBHBLE_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
OLHBHBLE_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
OLHBHBLE_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OLHBHBLE_00033 4.5e-203 yaaN P Belongs to the TelA family
OLHBHBLE_00034 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OLHBHBLE_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OLHBHBLE_00036 2.2e-54 yaaQ S protein conserved in bacteria
OLHBHBLE_00037 1.5e-71 yaaR S protein conserved in bacteria
OLHBHBLE_00038 2.2e-182 holB 2.7.7.7 L DNA polymerase III
OLHBHBLE_00039 2.1e-146 yaaT S stage 0 sporulation protein
OLHBHBLE_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
OLHBHBLE_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
OLHBHBLE_00042 1.5e-49 yazA L endonuclease containing a URI domain
OLHBHBLE_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OLHBHBLE_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
OLHBHBLE_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OLHBHBLE_00046 1.8e-144 tatD L hydrolase, TatD
OLHBHBLE_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
OLHBHBLE_00048 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OLHBHBLE_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OLHBHBLE_00050 3.3e-137 yabG S peptidase
OLHBHBLE_00051 7.8e-39 veg S protein conserved in bacteria
OLHBHBLE_00052 8.3e-27 sspF S DNA topological change
OLHBHBLE_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OLHBHBLE_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OLHBHBLE_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OLHBHBLE_00056 1e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OLHBHBLE_00057 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OLHBHBLE_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OLHBHBLE_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OLHBHBLE_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OLHBHBLE_00061 2.4e-39 yabK S Peptide ABC transporter permease
OLHBHBLE_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OLHBHBLE_00063 1.5e-92 spoVT K stage V sporulation protein
OLHBHBLE_00064 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLHBHBLE_00065 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OLHBHBLE_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OLHBHBLE_00067 1.5e-49 yabP S Sporulation protein YabP
OLHBHBLE_00068 3.9e-108 yabQ S spore cortex biosynthesis protein
OLHBHBLE_00069 1.1e-44 divIC D Septum formation initiator
OLHBHBLE_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OLHBHBLE_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OLHBHBLE_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
OLHBHBLE_00075 6.7e-187 KLT serine threonine protein kinase
OLHBHBLE_00076 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OLHBHBLE_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OLHBHBLE_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OLHBHBLE_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OLHBHBLE_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OLHBHBLE_00081 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
OLHBHBLE_00082 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OLHBHBLE_00083 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OLHBHBLE_00084 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OLHBHBLE_00085 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
OLHBHBLE_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OLHBHBLE_00087 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OLHBHBLE_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OLHBHBLE_00089 4.1e-30 yazB K transcriptional
OLHBHBLE_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OLHBHBLE_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OLHBHBLE_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00097 2e-08
OLHBHBLE_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00103 2.9e-76 ctsR K Belongs to the CtsR family
OLHBHBLE_00104 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OLHBHBLE_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OLHBHBLE_00106 0.0 clpC O Belongs to the ClpA ClpB family
OLHBHBLE_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OLHBHBLE_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OLHBHBLE_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OLHBHBLE_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OLHBHBLE_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OLHBHBLE_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OLHBHBLE_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
OLHBHBLE_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OLHBHBLE_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OLHBHBLE_00116 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OLHBHBLE_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
OLHBHBLE_00118 1.5e-115 sigH K Belongs to the sigma-70 factor family
OLHBHBLE_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OLHBHBLE_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
OLHBHBLE_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OLHBHBLE_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OLHBHBLE_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OLHBHBLE_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OLHBHBLE_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
OLHBHBLE_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OLHBHBLE_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OLHBHBLE_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
OLHBHBLE_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OLHBHBLE_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OLHBHBLE_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OLHBHBLE_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OLHBHBLE_00133 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
OLHBHBLE_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OLHBHBLE_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OLHBHBLE_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
OLHBHBLE_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OLHBHBLE_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OLHBHBLE_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OLHBHBLE_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OLHBHBLE_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OLHBHBLE_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OLHBHBLE_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OLHBHBLE_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OLHBHBLE_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OLHBHBLE_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OLHBHBLE_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OLHBHBLE_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OLHBHBLE_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OLHBHBLE_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OLHBHBLE_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OLHBHBLE_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OLHBHBLE_00153 1.9e-23 rpmD J Ribosomal protein L30
OLHBHBLE_00154 1.8e-72 rplO J binds to the 23S rRNA
OLHBHBLE_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OLHBHBLE_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OLHBHBLE_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
OLHBHBLE_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OLHBHBLE_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OLHBHBLE_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OLHBHBLE_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OLHBHBLE_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OLHBHBLE_00163 3.6e-58 rplQ J Ribosomal protein L17
OLHBHBLE_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OLHBHBLE_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OLHBHBLE_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OLHBHBLE_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OLHBHBLE_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OLHBHBLE_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OLHBHBLE_00170 8.2e-145 ybaJ Q Methyltransferase domain
OLHBHBLE_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
OLHBHBLE_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLHBHBLE_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OLHBHBLE_00174 1.2e-84 gerD
OLHBHBLE_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OLHBHBLE_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
OLHBHBLE_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00178 3.3e-39 S COG NOG15344 non supervised orthologous group
OLHBHBLE_00181 2e-08
OLHBHBLE_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00186 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00187 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
OLHBHBLE_00189 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
OLHBHBLE_00190 2.2e-142 ybbA S Putative esterase
OLHBHBLE_00191 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_00192 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_00193 7.2e-167 feuA P Iron-uptake system-binding protein
OLHBHBLE_00194 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
OLHBHBLE_00195 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
OLHBHBLE_00196 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OLHBHBLE_00197 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
OLHBHBLE_00198 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLHBHBLE_00199 1.1e-150 ybbH K transcriptional
OLHBHBLE_00200 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OLHBHBLE_00201 6.4e-87 ybbJ J acetyltransferase
OLHBHBLE_00202 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OLHBHBLE_00208 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_00209 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OLHBHBLE_00210 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OLHBHBLE_00211 3e-225 ybbR S protein conserved in bacteria
OLHBHBLE_00212 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OLHBHBLE_00213 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OLHBHBLE_00214 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OLHBHBLE_00215 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
OLHBHBLE_00216 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OLHBHBLE_00217 3.6e-219 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OLHBHBLE_00218 0.0 ybcC S Belongs to the UPF0753 family
OLHBHBLE_00219 3.7e-96 can 4.2.1.1 P carbonic anhydrase
OLHBHBLE_00220 3.9e-47
OLHBHBLE_00221 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
OLHBHBLE_00222 5.1e-50 ybzH K Helix-turn-helix domain
OLHBHBLE_00223 2e-203 ybcL EGP Major facilitator Superfamily
OLHBHBLE_00225 9.1e-239 J 4Fe-4S single cluster domain
OLHBHBLE_00226 1.6e-277 V CAAX protease self-immunity
OLHBHBLE_00227 1.9e-135 skfE V ABC transporter
OLHBHBLE_00228 4e-248 skfF S ABC transporter
OLHBHBLE_00229 7.8e-91 C HEAT repeats
OLHBHBLE_00230 9.6e-79 txn CO Thioredoxin-like
OLHBHBLE_00231 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OLHBHBLE_00232 1.5e-123 T Transcriptional regulatory protein, C terminal
OLHBHBLE_00233 1.8e-173 T His Kinase A (phospho-acceptor) domain
OLHBHBLE_00235 1.6e-140 KLT Protein tyrosine kinase
OLHBHBLE_00236 4.8e-154 ybdN
OLHBHBLE_00237 1.5e-217 ybdO S Domain of unknown function (DUF4885)
OLHBHBLE_00238 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OLHBHBLE_00239 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
OLHBHBLE_00240 4.9e-30 ybxH S Family of unknown function (DUF5370)
OLHBHBLE_00241 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
OLHBHBLE_00242 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OLHBHBLE_00243 4.9e-41 ybyB
OLHBHBLE_00244 1.8e-290 ybeC E amino acid
OLHBHBLE_00245 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OLHBHBLE_00246 7.3e-258 glpT G -transporter
OLHBHBLE_00247 2.9e-35 S Protein of unknown function (DUF2651)
OLHBHBLE_00248 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
OLHBHBLE_00249 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
OLHBHBLE_00251 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
OLHBHBLE_00252 8.8e-162 ybfH EG EamA-like transporter family
OLHBHBLE_00253 2.3e-145 msmR K AraC-like ligand binding domain
OLHBHBLE_00254 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OLHBHBLE_00255 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
OLHBHBLE_00257 2.5e-169 S Alpha/beta hydrolase family
OLHBHBLE_00258 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OLHBHBLE_00259 2.7e-85 ybfM S SNARE associated Golgi protein
OLHBHBLE_00260 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OLHBHBLE_00261 3.2e-46 ybfN
OLHBHBLE_00262 4.3e-258 S Erythromycin esterase
OLHBHBLE_00263 6.7e-167 ybfP K Transcriptional regulator
OLHBHBLE_00264 3.9e-192 yceA S Belongs to the UPF0176 family
OLHBHBLE_00265 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OLHBHBLE_00266 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLHBHBLE_00267 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OLHBHBLE_00268 4.9e-128 K UTRA
OLHBHBLE_00270 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OLHBHBLE_00271 6.7e-262 mmuP E amino acid
OLHBHBLE_00272 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
OLHBHBLE_00273 2.3e-257 agcS E Sodium alanine symporter
OLHBHBLE_00274 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
OLHBHBLE_00275 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
OLHBHBLE_00276 9e-170 glnL T Regulator
OLHBHBLE_00277 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
OLHBHBLE_00278 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLHBHBLE_00279 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
OLHBHBLE_00280 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OLHBHBLE_00281 1.5e-124 ycbG K FCD
OLHBHBLE_00282 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
OLHBHBLE_00283 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
OLHBHBLE_00284 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
OLHBHBLE_00285 7.3e-172 eamA1 EG spore germination
OLHBHBLE_00286 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_00287 2.4e-170 T PhoQ Sensor
OLHBHBLE_00288 4.8e-168 ycbN V ABC transporter, ATP-binding protein
OLHBHBLE_00289 2.1e-115 S ABC-2 family transporter protein
OLHBHBLE_00290 8.2e-53 ycbP S Protein of unknown function (DUF2512)
OLHBHBLE_00291 1.3e-78 sleB 3.5.1.28 M Cell wall
OLHBHBLE_00292 6.6e-136 ycbR T vWA found in TerF C terminus
OLHBHBLE_00293 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
OLHBHBLE_00294 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OLHBHBLE_00295 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OLHBHBLE_00296 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OLHBHBLE_00297 6.2e-210 ycbU E Selenocysteine lyase
OLHBHBLE_00298 5.8e-229 lmrB EGP the major facilitator superfamily
OLHBHBLE_00299 4.8e-102 yxaF K Transcriptional regulator
OLHBHBLE_00300 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
OLHBHBLE_00301 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OLHBHBLE_00302 2e-59 S RDD family
OLHBHBLE_00303 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
OLHBHBLE_00304 2e-161 2.7.13.3 T GHKL domain
OLHBHBLE_00305 1.2e-126 lytR_2 T LytTr DNA-binding domain
OLHBHBLE_00306 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
OLHBHBLE_00307 4.5e-203 natB CP ABC-2 family transporter protein
OLHBHBLE_00308 1.6e-174 yccK C Aldo keto reductase
OLHBHBLE_00309 6.6e-177 ycdA S Domain of unknown function (DUF5105)
OLHBHBLE_00310 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_00311 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_00312 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
OLHBHBLE_00313 5.5e-174 S response regulator aspartate phosphatase
OLHBHBLE_00314 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
OLHBHBLE_00315 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
OLHBHBLE_00316 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
OLHBHBLE_00317 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OLHBHBLE_00318 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OLHBHBLE_00319 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLHBHBLE_00320 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
OLHBHBLE_00321 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
OLHBHBLE_00322 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
OLHBHBLE_00323 6.3e-137 terC P Protein of unknown function (DUF475)
OLHBHBLE_00324 0.0 yceG S Putative component of 'biosynthetic module'
OLHBHBLE_00325 2e-192 yceH P Belongs to the TelA family
OLHBHBLE_00326 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
OLHBHBLE_00327 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
OLHBHBLE_00328 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
OLHBHBLE_00329 5.1e-229 proV 3.6.3.32 E glycine betaine
OLHBHBLE_00330 1.3e-127 opuAB P glycine betaine
OLHBHBLE_00331 5.3e-164 opuAC E glycine betaine
OLHBHBLE_00332 1.2e-219 amhX S amidohydrolase
OLHBHBLE_00333 1e-257 ycgA S Membrane
OLHBHBLE_00334 1.1e-98 ycgB
OLHBHBLE_00335 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
OLHBHBLE_00336 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OLHBHBLE_00337 6.5e-293 lctP C L-lactate permease
OLHBHBLE_00338 6.2e-269 mdr EGP Major facilitator Superfamily
OLHBHBLE_00339 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_00340 6.8e-113 ycgF E Lysine exporter protein LysE YggA
OLHBHBLE_00341 1.2e-151 yqcI S YqcI/YcgG family
OLHBHBLE_00342 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OLHBHBLE_00343 2.4e-112 ycgI S Domain of unknown function (DUF1989)
OLHBHBLE_00344 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OLHBHBLE_00345 2.5e-109 tmrB S AAA domain
OLHBHBLE_00346 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OLHBHBLE_00347 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
OLHBHBLE_00348 2.2e-179 oxyR3 K LysR substrate binding domain
OLHBHBLE_00349 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
OLHBHBLE_00350 2.9e-145 ycgL S Predicted nucleotidyltransferase
OLHBHBLE_00351 5.1e-170 ycgM E Proline dehydrogenase
OLHBHBLE_00352 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OLHBHBLE_00353 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLHBHBLE_00354 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
OLHBHBLE_00355 2.6e-147 ycgQ S membrane
OLHBHBLE_00356 1.2e-139 ycgR S permeases
OLHBHBLE_00357 5.7e-163 I alpha/beta hydrolase fold
OLHBHBLE_00358 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OLHBHBLE_00359 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OLHBHBLE_00360 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
OLHBHBLE_00361 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OLHBHBLE_00362 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OLHBHBLE_00363 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
OLHBHBLE_00364 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
OLHBHBLE_00365 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
OLHBHBLE_00366 5.5e-109 yciB M ErfK YbiS YcfS YnhG
OLHBHBLE_00367 1.4e-228 yciC S GTPases (G3E family)
OLHBHBLE_00368 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
OLHBHBLE_00369 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
OLHBHBLE_00372 3.3e-77 yckC S membrane
OLHBHBLE_00373 3.5e-52 yckD S Protein of unknown function (DUF2680)
OLHBHBLE_00374 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLHBHBLE_00375 3.4e-70 nin S Competence protein J (ComJ)
OLHBHBLE_00376 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
OLHBHBLE_00377 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
OLHBHBLE_00378 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
OLHBHBLE_00379 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
OLHBHBLE_00380 1.3e-63 hxlR K transcriptional
OLHBHBLE_00381 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_00382 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_00383 7.2e-115 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_00384 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
OLHBHBLE_00385 5.7e-140 srfAD Q thioesterase
OLHBHBLE_00386 4.2e-228 EGP Major Facilitator Superfamily
OLHBHBLE_00387 4.9e-91 S YcxB-like protein
OLHBHBLE_00388 7.4e-164 ycxC EG EamA-like transporter family
OLHBHBLE_00389 4.4e-255 ycxD K GntR family transcriptional regulator
OLHBHBLE_00390 4.4e-75 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
OLHBHBLE_00391 4.4e-115 yczE S membrane
OLHBHBLE_00392 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OLHBHBLE_00393 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
OLHBHBLE_00394 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OLHBHBLE_00395 4.9e-162 bsdA K LysR substrate binding domain
OLHBHBLE_00396 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OLHBHBLE_00397 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OLHBHBLE_00398 4e-39 bsdD 4.1.1.61 S response to toxic substance
OLHBHBLE_00399 1.1e-83 yclD
OLHBHBLE_00400 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
OLHBHBLE_00401 1.5e-267 dtpT E amino acid peptide transporter
OLHBHBLE_00402 2.9e-310 yclG M Pectate lyase superfamily protein
OLHBHBLE_00404 6.8e-282 gerKA EG Spore germination protein
OLHBHBLE_00405 1.3e-232 gerKC S spore germination
OLHBHBLE_00406 9.9e-200 gerKB F Spore germination protein
OLHBHBLE_00407 3.9e-122 yclH P ABC transporter
OLHBHBLE_00408 1.7e-204 yclI V ABC transporter (permease) YclI
OLHBHBLE_00409 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_00410 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
OLHBHBLE_00411 5.2e-71 S aspartate phosphatase
OLHBHBLE_00414 1.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
OLHBHBLE_00415 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_00416 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_00417 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OLHBHBLE_00418 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OLHBHBLE_00419 1.4e-251 ycnB EGP Major facilitator Superfamily
OLHBHBLE_00420 6.5e-154 ycnC K Transcriptional regulator
OLHBHBLE_00421 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
OLHBHBLE_00422 1.6e-45 ycnE S Monooxygenase
OLHBHBLE_00423 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
OLHBHBLE_00424 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLHBHBLE_00425 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OLHBHBLE_00426 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLHBHBLE_00427 6.1e-149 glcU U Glucose uptake
OLHBHBLE_00428 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_00429 1.3e-100 ycnI S protein conserved in bacteria
OLHBHBLE_00430 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
OLHBHBLE_00431 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
OLHBHBLE_00432 7.3e-56
OLHBHBLE_00433 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
OLHBHBLE_00434 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OLHBHBLE_00435 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OLHBHBLE_00436 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OLHBHBLE_00437 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OLHBHBLE_00438 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OLHBHBLE_00439 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
OLHBHBLE_00440 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OLHBHBLE_00442 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OLHBHBLE_00443 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
OLHBHBLE_00444 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
OLHBHBLE_00445 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
OLHBHBLE_00446 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OLHBHBLE_00447 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OLHBHBLE_00448 1.2e-132 kipR K Transcriptional regulator
OLHBHBLE_00449 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
OLHBHBLE_00451 1.4e-49 yczJ S biosynthesis
OLHBHBLE_00452 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OLHBHBLE_00453 2.8e-176 ydhF S Oxidoreductase
OLHBHBLE_00454 0.0 mtlR K transcriptional regulator, MtlR
OLHBHBLE_00455 1.4e-294 ydaB IQ acyl-CoA ligase
OLHBHBLE_00456 1.1e-99 ydaC Q Methyltransferase domain
OLHBHBLE_00457 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_00458 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
OLHBHBLE_00459 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OLHBHBLE_00460 6.8e-77 ydaG 1.4.3.5 S general stress protein
OLHBHBLE_00461 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OLHBHBLE_00462 5.1e-47 ydzA EGP Major facilitator Superfamily
OLHBHBLE_00463 2.5e-74 lrpC K Transcriptional regulator
OLHBHBLE_00464 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OLHBHBLE_00465 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
OLHBHBLE_00466 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
OLHBHBLE_00467 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OLHBHBLE_00468 4.5e-233 ydaM M Glycosyl transferase family group 2
OLHBHBLE_00469 0.0 ydaN S Bacterial cellulose synthase subunit
OLHBHBLE_00470 0.0 ydaO E amino acid
OLHBHBLE_00471 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
OLHBHBLE_00472 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OLHBHBLE_00473 9.4e-40
OLHBHBLE_00474 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
OLHBHBLE_00476 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
OLHBHBLE_00477 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
OLHBHBLE_00479 8.9e-59 ydbB G Cupin domain
OLHBHBLE_00480 2.8e-63 ydbC S Domain of unknown function (DUF4937
OLHBHBLE_00481 3.2e-155 ydbD P Catalase
OLHBHBLE_00482 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OLHBHBLE_00483 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OLHBHBLE_00484 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
OLHBHBLE_00485 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OLHBHBLE_00486 4.4e-181 ydbI S AI-2E family transporter
OLHBHBLE_00487 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
OLHBHBLE_00488 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OLHBHBLE_00489 2.7e-52 ydbL
OLHBHBLE_00490 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OLHBHBLE_00491 1.1e-18 S Fur-regulated basic protein B
OLHBHBLE_00492 2.2e-07 S Fur-regulated basic protein A
OLHBHBLE_00493 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OLHBHBLE_00494 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OLHBHBLE_00495 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OLHBHBLE_00496 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OLHBHBLE_00497 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OLHBHBLE_00498 2.1e-82 ydbS S Bacterial PH domain
OLHBHBLE_00499 2.2e-263 ydbT S Membrane
OLHBHBLE_00500 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OLHBHBLE_00501 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OLHBHBLE_00502 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OLHBHBLE_00503 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OLHBHBLE_00504 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OLHBHBLE_00505 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OLHBHBLE_00506 1.3e-143 rsbR T Positive regulator of sigma-B
OLHBHBLE_00507 5.2e-57 rsbS T antagonist
OLHBHBLE_00508 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OLHBHBLE_00509 7.1e-189 rsbU 3.1.3.3 KT phosphatase
OLHBHBLE_00510 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
OLHBHBLE_00511 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OLHBHBLE_00512 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLHBHBLE_00513 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OLHBHBLE_00517 1.5e-82 ydcG S EVE domain
OLHBHBLE_00518 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_00519 0.0 yhgF K COG2183 Transcriptional accessory protein
OLHBHBLE_00520 1.6e-84 ydcK S Belongs to the SprT family
OLHBHBLE_00528 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLHBHBLE_00529 2.4e-71 lrpA K transcriptional
OLHBHBLE_00530 3.9e-78 lrpB K transcriptional
OLHBHBLE_00531 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
OLHBHBLE_00532 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
OLHBHBLE_00533 5e-227 ydeG EGP Major facilitator Superfamily
OLHBHBLE_00538 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OLHBHBLE_00539 8.7e-30 cspL K Cold shock
OLHBHBLE_00540 6.1e-79 carD K Transcription factor
OLHBHBLE_00541 4.6e-35 ydzE EG spore germination
OLHBHBLE_00542 1.1e-166 rhaS5 K AraC-like ligand binding domain
OLHBHBLE_00543 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OLHBHBLE_00544 2.5e-166 ydeE K AraC family transcriptional regulator
OLHBHBLE_00545 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLHBHBLE_00546 3.4e-220 ydeG EGP Major facilitator superfamily
OLHBHBLE_00547 2.9e-47 ydeH
OLHBHBLE_00548 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
OLHBHBLE_00549 4e-116
OLHBHBLE_00550 1.8e-153 ydeK EG -transporter
OLHBHBLE_00551 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLHBHBLE_00552 4.2e-74 maoC I N-terminal half of MaoC dehydratase
OLHBHBLE_00553 8.6e-107 ydeN S Serine hydrolase
OLHBHBLE_00554 1.1e-58 K HxlR-like helix-turn-helix
OLHBHBLE_00555 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OLHBHBLE_00556 4.8e-69 ydeP K Transcriptional regulator
OLHBHBLE_00557 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
OLHBHBLE_00558 1.2e-195 ydeR EGP Major facilitator Superfamily
OLHBHBLE_00559 8.4e-105 ydeS K Transcriptional regulator
OLHBHBLE_00560 1.3e-57 arsR K transcriptional
OLHBHBLE_00561 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OLHBHBLE_00562 7.2e-149 ydfB J GNAT acetyltransferase
OLHBHBLE_00563 1e-162 ydfC EG EamA-like transporter family
OLHBHBLE_00564 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLHBHBLE_00565 5.9e-117 ydfE S Flavin reductase like domain
OLHBHBLE_00566 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
OLHBHBLE_00567 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OLHBHBLE_00569 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
OLHBHBLE_00570 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLHBHBLE_00571 0.0 ydfJ S drug exporters of the RND superfamily
OLHBHBLE_00572 1.9e-177 S Alpha/beta hydrolase family
OLHBHBLE_00573 5.9e-118 S Protein of unknown function (DUF554)
OLHBHBLE_00574 3.2e-147 K Bacterial transcription activator, effector binding domain
OLHBHBLE_00575 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OLHBHBLE_00576 9.6e-112 ydfN C nitroreductase
OLHBHBLE_00577 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OLHBHBLE_00578 8.8e-63 mhqP S DoxX
OLHBHBLE_00579 1.3e-57 traF CO Thioredoxin
OLHBHBLE_00580 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
OLHBHBLE_00581 6.3e-29
OLHBHBLE_00583 4.4e-118 ydfR S Protein of unknown function (DUF421)
OLHBHBLE_00584 5.2e-122 ydfS S Protein of unknown function (DUF421)
OLHBHBLE_00585 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
OLHBHBLE_00586 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
OLHBHBLE_00587 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
OLHBHBLE_00588 1.5e-101 K Bacterial regulatory proteins, tetR family
OLHBHBLE_00589 1.9e-53 S DoxX-like family
OLHBHBLE_00590 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
OLHBHBLE_00591 4.2e-308 expZ S ABC transporter
OLHBHBLE_00592 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
OLHBHBLE_00593 4.6e-91 dinB S DinB family
OLHBHBLE_00594 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_00595 0.0 ydgH S drug exporters of the RND superfamily
OLHBHBLE_00596 1e-113 drgA C nitroreductase
OLHBHBLE_00597 1.1e-69 ydgJ K Winged helix DNA-binding domain
OLHBHBLE_00598 2.5e-209 tcaB EGP Major facilitator Superfamily
OLHBHBLE_00599 1.2e-121 ydhB S membrane transporter protein
OLHBHBLE_00600 6.5e-122 ydhC K FCD
OLHBHBLE_00601 3.3e-244 ydhD M Glycosyl hydrolase
OLHBHBLE_00602 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OLHBHBLE_00603 1.9e-127
OLHBHBLE_00604 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OLHBHBLE_00605 4.6e-69 frataxin S Domain of unknown function (DU1801)
OLHBHBLE_00607 4.1e-86 K Acetyltransferase (GNAT) domain
OLHBHBLE_00608 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
OLHBHBLE_00609 1.7e-99 ydhK M Protein of unknown function (DUF1541)
OLHBHBLE_00610 4.6e-200 pbuE EGP Major facilitator Superfamily
OLHBHBLE_00611 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
OLHBHBLE_00612 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
OLHBHBLE_00613 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OLHBHBLE_00614 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLHBHBLE_00615 3.9e-133 ydhQ K UTRA
OLHBHBLE_00616 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OLHBHBLE_00617 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
OLHBHBLE_00618 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OLHBHBLE_00619 8.7e-78 ydhU P Catalase
OLHBHBLE_00620 1.1e-16 ydhU P Manganese containing catalase
OLHBHBLE_00623 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00624 7.8e-08
OLHBHBLE_00626 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OLHBHBLE_00627 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OLHBHBLE_00628 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OLHBHBLE_00629 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OLHBHBLE_00630 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OLHBHBLE_00631 0.0 ydiF S ABC transporter
OLHBHBLE_00632 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OLHBHBLE_00633 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OLHBHBLE_00634 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OLHBHBLE_00635 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OLHBHBLE_00636 2.9e-27 ydiK S Domain of unknown function (DUF4305)
OLHBHBLE_00637 7.9e-129 ydiL S CAAX protease self-immunity
OLHBHBLE_00638 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OLHBHBLE_00639 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OLHBHBLE_00641 6.4e-66 KL Phage plasmid primase P4 family
OLHBHBLE_00642 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
OLHBHBLE_00643 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
OLHBHBLE_00645 1.2e-199 V AAA domain (dynein-related subfamily)
OLHBHBLE_00646 4.9e-257 J LlaJI restriction endonuclease
OLHBHBLE_00647 1.1e-08 ydjC S Abhydrolase domain containing 18
OLHBHBLE_00648 0.0 K NB-ARC domain
OLHBHBLE_00649 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
OLHBHBLE_00650 7.1e-256 gutA G MFS/sugar transport protein
OLHBHBLE_00651 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
OLHBHBLE_00652 5.1e-114 pspA KT Phage shock protein A
OLHBHBLE_00653 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OLHBHBLE_00654 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
OLHBHBLE_00655 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
OLHBHBLE_00656 4.7e-196 S Ion transport 2 domain protein
OLHBHBLE_00657 2.7e-258 iolT EGP Major facilitator Superfamily
OLHBHBLE_00658 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OLHBHBLE_00659 4.5e-64 ydjM M Lytic transglycolase
OLHBHBLE_00660 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
OLHBHBLE_00662 1.4e-34 ydjO S Cold-inducible protein YdjO
OLHBHBLE_00663 9.5e-160 ydjP I Alpha/beta hydrolase family
OLHBHBLE_00664 2.4e-181 yeaA S Protein of unknown function (DUF4003)
OLHBHBLE_00665 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OLHBHBLE_00666 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OLHBHBLE_00667 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OLHBHBLE_00668 1.6e-177 yeaC S COG0714 MoxR-like ATPases
OLHBHBLE_00669 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OLHBHBLE_00670 0.0 yebA E COG1305 Transglutaminase-like enzymes
OLHBHBLE_00671 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OLHBHBLE_00672 6e-212 pbuG S permease
OLHBHBLE_00673 1.1e-118 yebC M Membrane
OLHBHBLE_00675 4e-93 yebE S UPF0316 protein
OLHBHBLE_00676 8e-28 yebG S NETI protein
OLHBHBLE_00677 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OLHBHBLE_00678 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OLHBHBLE_00679 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OLHBHBLE_00680 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OLHBHBLE_00681 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OLHBHBLE_00682 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OLHBHBLE_00683 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OLHBHBLE_00684 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OLHBHBLE_00685 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OLHBHBLE_00686 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OLHBHBLE_00687 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OLHBHBLE_00688 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
OLHBHBLE_00689 3.5e-73 K helix_turn_helix ASNC type
OLHBHBLE_00690 2.3e-232 yjeH E Amino acid permease
OLHBHBLE_00691 2.7e-27 S Protein of unknown function (DUF2892)
OLHBHBLE_00692 0.0 yerA 3.5.4.2 F adenine deaminase
OLHBHBLE_00693 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
OLHBHBLE_00694 4.8e-51 yerC S protein conserved in bacteria
OLHBHBLE_00695 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
OLHBHBLE_00697 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OLHBHBLE_00698 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OLHBHBLE_00699 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OLHBHBLE_00700 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
OLHBHBLE_00701 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
OLHBHBLE_00702 1.6e-123 sapB S MgtC SapB transporter
OLHBHBLE_00703 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLHBHBLE_00704 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OLHBHBLE_00705 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OLHBHBLE_00706 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OLHBHBLE_00707 4e-156 yerO K Transcriptional regulator
OLHBHBLE_00708 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OLHBHBLE_00709 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OLHBHBLE_00710 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OLHBHBLE_00711 3.2e-98 L Recombinase
OLHBHBLE_00712 3.2e-53 L Resolvase, N terminal domain
OLHBHBLE_00713 0.0 yeeA V Type II restriction enzyme, methylase subunits
OLHBHBLE_00714 0.0 yeeB L DEAD-like helicases superfamily
OLHBHBLE_00715 1.8e-212 pstS P T5orf172
OLHBHBLE_00717 6.2e-31 S Colicin immunity protein / pyocin immunity protein
OLHBHBLE_00718 5.5e-83 S Protein of unknown function, DUF600
OLHBHBLE_00719 0.0 L nucleic acid phosphodiester bond hydrolysis
OLHBHBLE_00720 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
OLHBHBLE_00721 5.5e-214 S Tetratricopeptide repeat
OLHBHBLE_00723 9.4e-127 yeeN K transcriptional regulatory protein
OLHBHBLE_00725 1.2e-103 dhaR3 K Transcriptional regulator
OLHBHBLE_00726 9.7e-82 yesE S SnoaL-like domain
OLHBHBLE_00727 2.2e-159 yesF GM NAD(P)H-binding
OLHBHBLE_00728 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
OLHBHBLE_00729 1.5e-45 cotJB S CotJB protein
OLHBHBLE_00730 5.2e-104 cotJC P Spore Coat
OLHBHBLE_00731 4.2e-103 yesJ K Acetyltransferase (GNAT) family
OLHBHBLE_00733 4.4e-104 yesL S Protein of unknown function, DUF624
OLHBHBLE_00734 0.0 yesM 2.7.13.3 T Histidine kinase
OLHBHBLE_00735 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
OLHBHBLE_00736 5e-248 yesO G Bacterial extracellular solute-binding protein
OLHBHBLE_00737 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
OLHBHBLE_00738 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
OLHBHBLE_00739 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
OLHBHBLE_00740 0.0 yesS K Transcriptional regulator
OLHBHBLE_00741 3.8e-133 E GDSL-like Lipase/Acylhydrolase
OLHBHBLE_00742 8.9e-132 yesU S Domain of unknown function (DUF1961)
OLHBHBLE_00743 1e-113 yesV S Protein of unknown function, DUF624
OLHBHBLE_00744 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
OLHBHBLE_00745 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
OLHBHBLE_00746 1.7e-108 yesY E GDSL-like Lipase/Acylhydrolase
OLHBHBLE_00747 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
OLHBHBLE_00748 0.0 yetA
OLHBHBLE_00749 9.6e-291 lplA G Bacterial extracellular solute-binding protein
OLHBHBLE_00750 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
OLHBHBLE_00751 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
OLHBHBLE_00752 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OLHBHBLE_00753 6.1e-123 yetF S membrane
OLHBHBLE_00754 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OLHBHBLE_00755 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLHBHBLE_00756 2.2e-34
OLHBHBLE_00757 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLHBHBLE_00758 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLHBHBLE_00759 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
OLHBHBLE_00760 5.3e-105 yetJ S Belongs to the BI1 family
OLHBHBLE_00761 5.4e-159 yetK EG EamA-like transporter family
OLHBHBLE_00762 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_00763 7.8e-213 yetM CH FAD binding domain
OLHBHBLE_00764 3.6e-199 yetN S Protein of unknown function (DUF3900)
OLHBHBLE_00765 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OLHBHBLE_00766 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OLHBHBLE_00767 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
OLHBHBLE_00768 1.9e-172 yfnG 4.2.1.45 M dehydratase
OLHBHBLE_00769 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
OLHBHBLE_00770 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
OLHBHBLE_00771 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
OLHBHBLE_00772 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
OLHBHBLE_00773 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OLHBHBLE_00774 1.3e-241 yfnA E amino acid
OLHBHBLE_00775 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLHBHBLE_00776 1.1e-113 yfmS NT chemotaxis protein
OLHBHBLE_00777 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OLHBHBLE_00778 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
OLHBHBLE_00779 2.8e-70 yfmP K transcriptional
OLHBHBLE_00780 1.5e-209 yfmO EGP Major facilitator Superfamily
OLHBHBLE_00781 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OLHBHBLE_00782 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OLHBHBLE_00783 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
OLHBHBLE_00784 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
OLHBHBLE_00785 7.7e-214 G Major Facilitator Superfamily
OLHBHBLE_00786 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
OLHBHBLE_00787 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
OLHBHBLE_00788 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_00789 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_00790 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OLHBHBLE_00791 2.9e-24 S Protein of unknown function (DUF3212)
OLHBHBLE_00792 7.6e-58 yflT S Heat induced stress protein YflT
OLHBHBLE_00793 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
OLHBHBLE_00794 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
OLHBHBLE_00795 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OLHBHBLE_00796 8.9e-119 citT T response regulator
OLHBHBLE_00797 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
OLHBHBLE_00799 8.5e-227 citM C Citrate transporter
OLHBHBLE_00800 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OLHBHBLE_00801 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OLHBHBLE_00802 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OLHBHBLE_00803 9e-124 yflK S protein conserved in bacteria
OLHBHBLE_00804 4e-18 yflJ S Protein of unknown function (DUF2639)
OLHBHBLE_00805 4.1e-19 yflI
OLHBHBLE_00806 2.4e-50 yflH S Protein of unknown function (DUF3243)
OLHBHBLE_00807 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
OLHBHBLE_00808 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OLHBHBLE_00809 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OLHBHBLE_00810 6e-67 yhdN S Domain of unknown function (DUF1992)
OLHBHBLE_00811 3.2e-256 agcS_1 E Sodium alanine symporter
OLHBHBLE_00812 1.6e-194 E Spore germination protein
OLHBHBLE_00814 5.1e-207 yfkR S spore germination
OLHBHBLE_00815 1.5e-283 yfkQ EG Spore germination protein
OLHBHBLE_00816 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLHBHBLE_00817 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OLHBHBLE_00818 1.8e-133 treR K transcriptional
OLHBHBLE_00819 1.6e-125 yfkO C nitroreductase
OLHBHBLE_00820 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
OLHBHBLE_00821 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
OLHBHBLE_00822 6.8e-207 ydiM EGP Major facilitator Superfamily
OLHBHBLE_00823 2.1e-29 yfkK S Belongs to the UPF0435 family
OLHBHBLE_00824 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OLHBHBLE_00825 8.4e-51 yfkI S gas vesicle protein
OLHBHBLE_00826 9.7e-144 yihY S Belongs to the UPF0761 family
OLHBHBLE_00827 5e-08
OLHBHBLE_00828 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
OLHBHBLE_00829 6.1e-183 cax P COG0387 Ca2 H antiporter
OLHBHBLE_00830 1.2e-146 yfkD S YfkD-like protein
OLHBHBLE_00831 6e-149 yfkC M Mechanosensitive ion channel
OLHBHBLE_00832 5.4e-222 yfkA S YfkB-like domain
OLHBHBLE_00833 1.1e-26 yfjT
OLHBHBLE_00834 2.6e-154 pdaA G deacetylase
OLHBHBLE_00835 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OLHBHBLE_00836 1.7e-184 corA P Mediates influx of magnesium ions
OLHBHBLE_00837 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OLHBHBLE_00838 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OLHBHBLE_00839 1.6e-39 S YfzA-like protein
OLHBHBLE_00840 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OLHBHBLE_00841 3.9e-86 yfjM S Psort location Cytoplasmic, score
OLHBHBLE_00842 3e-29 yfjL
OLHBHBLE_00843 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OLHBHBLE_00844 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OLHBHBLE_00845 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OLHBHBLE_00846 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OLHBHBLE_00847 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OLHBHBLE_00848 1.2e-25 sspH S Belongs to the SspH family
OLHBHBLE_00849 4e-56 yfjF S UPF0060 membrane protein
OLHBHBLE_00850 1.3e-80 S Family of unknown function (DUF5381)
OLHBHBLE_00851 1.8e-101 yfjD S Family of unknown function (DUF5381)
OLHBHBLE_00852 4.1e-144 yfjC
OLHBHBLE_00853 9.2e-191 yfjB
OLHBHBLE_00854 1.1e-44 yfjA S Belongs to the WXG100 family
OLHBHBLE_00855 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OLHBHBLE_00856 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
OLHBHBLE_00857 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLHBHBLE_00858 2.1e-310 yfiB3 V ABC transporter
OLHBHBLE_00859 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLHBHBLE_00860 9.8e-65 mhqP S DoxX
OLHBHBLE_00861 5.7e-163 yfiE 1.13.11.2 S glyoxalase
OLHBHBLE_00862 1.5e-177 K AraC-like ligand binding domain
OLHBHBLE_00863 1.8e-262 iolT EGP Major facilitator Superfamily
OLHBHBLE_00864 8.4e-184 G Xylose isomerase
OLHBHBLE_00865 1.1e-233 S Oxidoreductase
OLHBHBLE_00867 1.1e-214 yxjM T Histidine kinase
OLHBHBLE_00868 3.2e-113 KT LuxR family transcriptional regulator
OLHBHBLE_00869 6.2e-171 V ABC transporter, ATP-binding protein
OLHBHBLE_00870 9.8e-214 V ABC-2 family transporter protein
OLHBHBLE_00871 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
OLHBHBLE_00872 8.3e-99 padR K transcriptional
OLHBHBLE_00873 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OLHBHBLE_00874 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OLHBHBLE_00875 2e-109 yfiR K Transcriptional regulator
OLHBHBLE_00876 5.1e-221 yfiS EGP Major facilitator Superfamily
OLHBHBLE_00877 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
OLHBHBLE_00878 8.7e-287 yfiU EGP Major facilitator Superfamily
OLHBHBLE_00879 3.1e-81 yfiV K transcriptional
OLHBHBLE_00880 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OLHBHBLE_00881 6.2e-182 yfiY P ABC transporter substrate-binding protein
OLHBHBLE_00882 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_00883 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_00884 1.8e-167 yfhB 5.3.3.17 S PhzF family
OLHBHBLE_00885 3.9e-107 yfhC C nitroreductase
OLHBHBLE_00886 2.1e-25 yfhD S YfhD-like protein
OLHBHBLE_00888 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
OLHBHBLE_00889 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
OLHBHBLE_00890 9.7e-52 yfhH S Protein of unknown function (DUF1811)
OLHBHBLE_00892 1.1e-209 yfhI EGP Major facilitator Superfamily
OLHBHBLE_00893 6.2e-20 sspK S reproduction
OLHBHBLE_00894 1.3e-44 yfhJ S WVELL protein
OLHBHBLE_00895 9.2e-92 batE T Bacterial SH3 domain homologues
OLHBHBLE_00896 3.5e-51 yfhL S SdpI/YhfL protein family
OLHBHBLE_00897 6.7e-172 yfhM S Alpha beta hydrolase
OLHBHBLE_00898 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLHBHBLE_00899 0.0 yfhO S Bacterial membrane protein YfhO
OLHBHBLE_00900 5.5e-186 yfhP S membrane-bound metal-dependent
OLHBHBLE_00901 7.8e-212 mutY L A G-specific
OLHBHBLE_00902 6.9e-36 yfhS
OLHBHBLE_00903 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_00904 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
OLHBHBLE_00905 1.5e-37 ygaB S YgaB-like protein
OLHBHBLE_00906 1.3e-104 ygaC J Belongs to the UPF0374 family
OLHBHBLE_00907 1.8e-301 ygaD V ABC transporter
OLHBHBLE_00908 8.7e-180 ygaE S Membrane
OLHBHBLE_00909 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OLHBHBLE_00910 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
OLHBHBLE_00911 4e-80 perR P Belongs to the Fur family
OLHBHBLE_00912 1.5e-56 ygzB S UPF0295 protein
OLHBHBLE_00913 6.7e-167 ygxA S Nucleotidyltransferase-like
OLHBHBLE_00914 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_00919 7.8e-08
OLHBHBLE_00927 2e-08
OLHBHBLE_00931 2.7e-143 spo0M S COG4326 Sporulation control protein
OLHBHBLE_00932 3e-27
OLHBHBLE_00933 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OLHBHBLE_00934 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OLHBHBLE_00935 1.9e-266 ygaK C Berberine and berberine like
OLHBHBLE_00937 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OLHBHBLE_00938 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OLHBHBLE_00939 1.7e-171 ssuA M Sulfonate ABC transporter
OLHBHBLE_00940 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OLHBHBLE_00941 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OLHBHBLE_00943 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OLHBHBLE_00944 4.1e-78 ygaO
OLHBHBLE_00945 4.4e-29 K Transcriptional regulator
OLHBHBLE_00947 7.9e-114 yhzB S B3/4 domain
OLHBHBLE_00948 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OLHBHBLE_00949 4.4e-177 yhbB S Putative amidase domain
OLHBHBLE_00950 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OLHBHBLE_00951 1.2e-109 yhbD K Protein of unknown function (DUF4004)
OLHBHBLE_00952 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OLHBHBLE_00953 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OLHBHBLE_00954 0.0 prkA T Ser protein kinase
OLHBHBLE_00955 2.5e-225 yhbH S Belongs to the UPF0229 family
OLHBHBLE_00956 2.2e-76 yhbI K DNA-binding transcription factor activity
OLHBHBLE_00957 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
OLHBHBLE_00958 3.1e-271 yhcA EGP Major facilitator Superfamily
OLHBHBLE_00959 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
OLHBHBLE_00960 2.8e-37 yhcC
OLHBHBLE_00961 7.8e-55
OLHBHBLE_00962 6.6e-60 yhcF K Transcriptional regulator
OLHBHBLE_00963 1.6e-123 yhcG V ABC transporter, ATP-binding protein
OLHBHBLE_00964 2.6e-166 yhcH V ABC transporter, ATP-binding protein
OLHBHBLE_00965 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OLHBHBLE_00966 1e-30 cspB K Cold-shock protein
OLHBHBLE_00967 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
OLHBHBLE_00968 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
OLHBHBLE_00969 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OLHBHBLE_00970 3.7e-44 yhcM
OLHBHBLE_00971 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OLHBHBLE_00972 1.1e-156 yhcP
OLHBHBLE_00973 5.2e-100 yhcQ M Spore coat protein
OLHBHBLE_00974 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
OLHBHBLE_00975 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OLHBHBLE_00976 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OLHBHBLE_00977 9.3e-68 yhcU S Family of unknown function (DUF5365)
OLHBHBLE_00978 8.3e-25 yhcV S COG0517 FOG CBS domain
OLHBHBLE_00979 9.1e-23 yhcV S COG0517 FOG CBS domain
OLHBHBLE_00980 4.6e-120 yhcW 5.4.2.6 S hydrolase
OLHBHBLE_00981 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OLHBHBLE_00982 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OLHBHBLE_00983 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OLHBHBLE_00984 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OLHBHBLE_00985 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OLHBHBLE_00986 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OLHBHBLE_00987 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OLHBHBLE_00988 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
OLHBHBLE_00989 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLHBHBLE_00990 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
OLHBHBLE_00991 1.2e-38 yhdB S YhdB-like protein
OLHBHBLE_00992 4.8e-54 yhdC S Protein of unknown function (DUF3889)
OLHBHBLE_00993 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OLHBHBLE_00994 3.5e-76 nsrR K Transcriptional regulator
OLHBHBLE_00995 8.7e-239 ygxB M Conserved TM helix
OLHBHBLE_00996 2.1e-276 ycgB S Stage V sporulation protein R
OLHBHBLE_00997 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OLHBHBLE_00998 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OLHBHBLE_00999 3.8e-162 citR K Transcriptional regulator
OLHBHBLE_01000 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
OLHBHBLE_01001 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_01002 3.4e-250 yhdG E amino acid
OLHBHBLE_01003 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OLHBHBLE_01004 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLHBHBLE_01005 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLHBHBLE_01006 8.1e-45 yhdK S Sigma-M inhibitor protein
OLHBHBLE_01007 6.6e-201 yhdL S Sigma factor regulator N-terminal
OLHBHBLE_01008 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_01009 1.5e-191 yhdN C Aldo keto reductase
OLHBHBLE_01010 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OLHBHBLE_01011 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OLHBHBLE_01012 4.1e-74 cueR K transcriptional
OLHBHBLE_01013 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
OLHBHBLE_01014 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OLHBHBLE_01015 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OLHBHBLE_01016 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OLHBHBLE_01017 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OLHBHBLE_01019 6.6e-204 yhdY M Mechanosensitive ion channel
OLHBHBLE_01020 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OLHBHBLE_01021 1.7e-151 yheN G deacetylase
OLHBHBLE_01022 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OLHBHBLE_01023 2.2e-233 nhaC C Na H antiporter
OLHBHBLE_01024 3.4e-84 nhaX T Belongs to the universal stress protein A family
OLHBHBLE_01025 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLHBHBLE_01026 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLHBHBLE_01027 3.7e-111 yheG GM NAD(P)H-binding
OLHBHBLE_01028 6.3e-28 sspB S spore protein
OLHBHBLE_01029 1.3e-36 yheE S Family of unknown function (DUF5342)
OLHBHBLE_01030 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OLHBHBLE_01031 4.3e-216 yheC HJ YheC/D like ATP-grasp
OLHBHBLE_01032 6.7e-204 yheB S Belongs to the UPF0754 family
OLHBHBLE_01033 9.5e-48 yheA S Belongs to the UPF0342 family
OLHBHBLE_01034 3.1e-206 yhaZ L DNA alkylation repair enzyme
OLHBHBLE_01035 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
OLHBHBLE_01036 7.1e-294 hemZ H coproporphyrinogen III oxidase
OLHBHBLE_01037 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
OLHBHBLE_01038 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
OLHBHBLE_01040 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
OLHBHBLE_01041 1.1e-26 S YhzD-like protein
OLHBHBLE_01042 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
OLHBHBLE_01043 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OLHBHBLE_01044 3.6e-227 yhaO L DNA repair exonuclease
OLHBHBLE_01045 0.0 yhaN L AAA domain
OLHBHBLE_01046 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
OLHBHBLE_01047 1.6e-21 yhaL S Sporulation protein YhaL
OLHBHBLE_01048 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OLHBHBLE_01049 8.7e-90 yhaK S Putative zincin peptidase
OLHBHBLE_01050 1.3e-54 yhaI S Protein of unknown function (DUF1878)
OLHBHBLE_01051 1e-113 hpr K Negative regulator of protease production and sporulation
OLHBHBLE_01052 7e-39 yhaH S YtxH-like protein
OLHBHBLE_01053 3.6e-80 trpP S Tryptophan transporter TrpP
OLHBHBLE_01054 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OLHBHBLE_01055 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OLHBHBLE_01056 4.6e-137 ecsA V transporter (ATP-binding protein)
OLHBHBLE_01057 1.8e-215 ecsB U ABC transporter
OLHBHBLE_01058 4.8e-115 ecsC S EcsC protein family
OLHBHBLE_01059 5e-150 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OLHBHBLE_01060 6e-57 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OLHBHBLE_01061 4.2e-248 yhfA C membrane
OLHBHBLE_01062 5.4e-10 1.15.1.2 C Rubrerythrin
OLHBHBLE_01063 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OLHBHBLE_01064 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OLHBHBLE_01065 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OLHBHBLE_01066 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OLHBHBLE_01067 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OLHBHBLE_01068 1.4e-101 yhgD K Transcriptional regulator
OLHBHBLE_01069 1e-238 yhgE S YhgE Pip N-terminal domain protein
OLHBHBLE_01070 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OLHBHBLE_01071 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
OLHBHBLE_01072 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
OLHBHBLE_01073 1.7e-72 3.4.13.21 S ASCH
OLHBHBLE_01074 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OLHBHBLE_01075 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OLHBHBLE_01076 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
OLHBHBLE_01077 2.6e-112 yhfK GM NmrA-like family
OLHBHBLE_01078 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OLHBHBLE_01079 1.9e-65 yhfM
OLHBHBLE_01080 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
OLHBHBLE_01081 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
OLHBHBLE_01082 9.2e-80 VY92_01935 K acetyltransferase
OLHBHBLE_01083 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
OLHBHBLE_01084 4.3e-159 yfmC M Periplasmic binding protein
OLHBHBLE_01085 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
OLHBHBLE_01086 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
OLHBHBLE_01087 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OLHBHBLE_01088 5e-91 bioY S BioY family
OLHBHBLE_01089 1.7e-182 hemAT NT chemotaxis protein
OLHBHBLE_01090 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OLHBHBLE_01091 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_01092 1.3e-32 yhzC S IDEAL
OLHBHBLE_01093 4.2e-109 comK K Competence transcription factor
OLHBHBLE_01094 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
OLHBHBLE_01095 7.8e-42 yhjA S Excalibur calcium-binding domain
OLHBHBLE_01096 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLHBHBLE_01097 6.9e-27 yhjC S Protein of unknown function (DUF3311)
OLHBHBLE_01098 5e-60 yhjD
OLHBHBLE_01099 9.1e-110 yhjE S SNARE associated Golgi protein
OLHBHBLE_01100 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
OLHBHBLE_01101 1.1e-286 yhjG CH FAD binding domain
OLHBHBLE_01102 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_01103 6.9e-215 glcP G Major Facilitator Superfamily
OLHBHBLE_01104 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
OLHBHBLE_01105 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
OLHBHBLE_01106 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
OLHBHBLE_01107 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
OLHBHBLE_01108 3.8e-202 abrB S membrane
OLHBHBLE_01109 3.1e-215 EGP Transmembrane secretion effector
OLHBHBLE_01110 0.0 S Sugar transport-related sRNA regulator N-term
OLHBHBLE_01111 1.9e-34 yhjQ C COG1145 Ferredoxin
OLHBHBLE_01112 2.2e-78 yhjR S Rubrerythrin
OLHBHBLE_01113 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OLHBHBLE_01114 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OLHBHBLE_01115 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OLHBHBLE_01116 0.0 sbcC L COG0419 ATPase involved in DNA repair
OLHBHBLE_01117 6e-51 yisB V COG1403 Restriction endonuclease
OLHBHBLE_01118 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
OLHBHBLE_01119 3e-66 gerPE S Spore germination protein GerPE
OLHBHBLE_01120 6.3e-24 gerPD S Spore germination protein
OLHBHBLE_01121 1.8e-54 gerPC S Spore germination protein
OLHBHBLE_01122 4e-34 gerPB S cell differentiation
OLHBHBLE_01123 1.9e-33 gerPA S Spore germination protein
OLHBHBLE_01124 1.5e-22 yisI S Spo0E like sporulation regulatory protein
OLHBHBLE_01125 1.7e-176 cotH M Spore Coat
OLHBHBLE_01126 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OLHBHBLE_01127 3e-57 yisL S UPF0344 protein
OLHBHBLE_01128 0.0 wprA O Belongs to the peptidase S8 family
OLHBHBLE_01129 7.2e-106 yisN S Protein of unknown function (DUF2777)
OLHBHBLE_01130 0.0 asnO 6.3.5.4 E Asparagine synthase
OLHBHBLE_01131 2.1e-88 yizA S Damage-inducible protein DinB
OLHBHBLE_01132 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
OLHBHBLE_01133 4e-243 yisQ V Mate efflux family protein
OLHBHBLE_01134 1.4e-161 yisR K Transcriptional regulator
OLHBHBLE_01135 2.4e-184 purR K helix_turn _helix lactose operon repressor
OLHBHBLE_01136 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
OLHBHBLE_01137 1.3e-93 yisT S DinB family
OLHBHBLE_01138 6.4e-108 argO S Lysine exporter protein LysE YggA
OLHBHBLE_01139 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OLHBHBLE_01140 4e-36 mcbG S Pentapeptide repeats (9 copies)
OLHBHBLE_01141 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OLHBHBLE_01142 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
OLHBHBLE_01143 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OLHBHBLE_01144 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OLHBHBLE_01145 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
OLHBHBLE_01146 1.9e-141 yitD 4.4.1.19 S synthase
OLHBHBLE_01147 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OLHBHBLE_01148 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OLHBHBLE_01149 4e-229 yitG EGP Major facilitator Superfamily
OLHBHBLE_01150 1.8e-161 yitH K Acetyltransferase (GNAT) domain
OLHBHBLE_01151 2e-82 yjcF S Acetyltransferase (GNAT) domain
OLHBHBLE_01152 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OLHBHBLE_01153 8.6e-55 yajQ S Belongs to the UPF0234 family
OLHBHBLE_01154 4e-161 cvfB S protein conserved in bacteria
OLHBHBLE_01155 8.5e-94
OLHBHBLE_01156 2.8e-171
OLHBHBLE_01157 1.5e-97 S Sporulation delaying protein SdpA
OLHBHBLE_01158 1.5e-58 K Transcriptional regulator PadR-like family
OLHBHBLE_01159 2e-95
OLHBHBLE_01160 1.4e-44 yitR S Domain of unknown function (DUF3784)
OLHBHBLE_01161 2.2e-311 nprB 3.4.24.28 E Peptidase M4
OLHBHBLE_01162 8.4e-159 yitS S protein conserved in bacteria
OLHBHBLE_01163 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
OLHBHBLE_01164 1.9e-72 ipi S Intracellular proteinase inhibitor
OLHBHBLE_01165 1.2e-17 S Protein of unknown function (DUF3813)
OLHBHBLE_01166 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
OLHBHBLE_01167 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
OLHBHBLE_01168 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
OLHBHBLE_01169 1.5e-22 pilT S Proteolipid membrane potential modulator
OLHBHBLE_01170 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
OLHBHBLE_01171 1.7e-88 norB G Major Facilitator Superfamily
OLHBHBLE_01172 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OLHBHBLE_01173 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OLHBHBLE_01174 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
OLHBHBLE_01175 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OLHBHBLE_01176 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OLHBHBLE_01177 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OLHBHBLE_01178 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OLHBHBLE_01179 9.5e-28 yjzC S YjzC-like protein
OLHBHBLE_01180 2.3e-16 yjzD S Protein of unknown function (DUF2929)
OLHBHBLE_01181 6.2e-142 yjaU I carboxylic ester hydrolase activity
OLHBHBLE_01182 7.3e-103 yjaV
OLHBHBLE_01183 1.1e-183 med S Transcriptional activator protein med
OLHBHBLE_01184 7.3e-26 comZ S ComZ
OLHBHBLE_01185 2.7e-22 yjzB
OLHBHBLE_01186 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OLHBHBLE_01187 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OLHBHBLE_01188 7.8e-151 yjaZ O Zn-dependent protease
OLHBHBLE_01189 1.8e-184 appD P Belongs to the ABC transporter superfamily
OLHBHBLE_01190 6.5e-187 appF E Belongs to the ABC transporter superfamily
OLHBHBLE_01191 3.5e-48 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OLHBHBLE_01192 1.9e-190 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OLHBHBLE_01193 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLHBHBLE_01194 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLHBHBLE_01195 5e-147 yjbA S Belongs to the UPF0736 family
OLHBHBLE_01196 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OLHBHBLE_01197 0.0 oppA E ABC transporter substrate-binding protein
OLHBHBLE_01198 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLHBHBLE_01199 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLHBHBLE_01200 3e-198 oppD P Belongs to the ABC transporter superfamily
OLHBHBLE_01201 5.5e-172 oppF E Belongs to the ABC transporter superfamily
OLHBHBLE_01202 8.6e-196 yjbB EGP Major Facilitator Superfamily
OLHBHBLE_01203 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLHBHBLE_01204 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OLHBHBLE_01205 6e-112 yjbE P Integral membrane protein TerC family
OLHBHBLE_01206 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OLHBHBLE_01207 2.3e-223 yjbF S Competence protein
OLHBHBLE_01208 0.0 pepF E oligoendopeptidase F
OLHBHBLE_01209 1.8e-20
OLHBHBLE_01211 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OLHBHBLE_01212 3.7e-72 yjbI S Bacterial-like globin
OLHBHBLE_01213 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OLHBHBLE_01214 2.4e-101 yjbK S protein conserved in bacteria
OLHBHBLE_01215 7.1e-62 yjbL S Belongs to the UPF0738 family
OLHBHBLE_01216 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
OLHBHBLE_01217 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OLHBHBLE_01218 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OLHBHBLE_01219 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OLHBHBLE_01220 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OLHBHBLE_01221 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OLHBHBLE_01222 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
OLHBHBLE_01223 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
OLHBHBLE_01224 3e-30 thiS H thiamine diphosphate biosynthetic process
OLHBHBLE_01225 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OLHBHBLE_01226 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OLHBHBLE_01227 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OLHBHBLE_01228 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OLHBHBLE_01229 5.9e-54 yjbX S Spore coat protein
OLHBHBLE_01230 5.2e-83 cotZ S Spore coat protein
OLHBHBLE_01231 3.4e-96 cotY S Spore coat protein Z
OLHBHBLE_01232 6.4e-77 cotX S Spore Coat Protein X and V domain
OLHBHBLE_01233 3e-32 cotW
OLHBHBLE_01234 2.3e-55 cotV S Spore Coat Protein X and V domain
OLHBHBLE_01235 8.7e-57 yjcA S Protein of unknown function (DUF1360)
OLHBHBLE_01238 2.9e-38 spoVIF S Stage VI sporulation protein F
OLHBHBLE_01239 0.0 yjcD 3.6.4.12 L DNA helicase
OLHBHBLE_01240 1.7e-38
OLHBHBLE_01241 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLHBHBLE_01242 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OLHBHBLE_01243 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
OLHBHBLE_01244 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OLHBHBLE_01245 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OLHBHBLE_01246 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
OLHBHBLE_01247 1.1e-212 yjcL S Protein of unknown function (DUF819)
OLHBHBLE_01250 2.1e-190 S Putative amidase domain
OLHBHBLE_01251 2.6e-44 yjcN
OLHBHBLE_01254 8.5e-81 L Transposase
OLHBHBLE_01255 1.6e-72 yjcP
OLHBHBLE_01256 4.1e-49 S YjcQ protein
OLHBHBLE_01257 1.1e-92 yqaS L DNA packaging
OLHBHBLE_01258 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
OLHBHBLE_01259 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
OLHBHBLE_01261 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
OLHBHBLE_01262 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
OLHBHBLE_01263 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
OLHBHBLE_01264 4.8e-51 yjdF S Protein of unknown function (DUF2992)
OLHBHBLE_01265 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
OLHBHBLE_01267 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OLHBHBLE_01268 4.2e-29 S Domain of unknown function (DUF4177)
OLHBHBLE_01269 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
OLHBHBLE_01270 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OLHBHBLE_01272 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
OLHBHBLE_01273 5.5e-83 S Protein of unknown function (DUF2690)
OLHBHBLE_01274 3.6e-21 yjfB S Putative motility protein
OLHBHBLE_01275 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
OLHBHBLE_01276 1.2e-45 T PhoQ Sensor
OLHBHBLE_01277 8.9e-104 yjgB S Domain of unknown function (DUF4309)
OLHBHBLE_01278 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
OLHBHBLE_01279 4.3e-95 yjgD S Protein of unknown function (DUF1641)
OLHBHBLE_01280 8.7e-07 S Domain of unknown function (DUF4352)
OLHBHBLE_01281 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
OLHBHBLE_01283 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OLHBHBLE_01284 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OLHBHBLE_01285 8.2e-30
OLHBHBLE_01286 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OLHBHBLE_01287 1.9e-122 ybbM S transport system, permease component
OLHBHBLE_01288 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
OLHBHBLE_01289 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
OLHBHBLE_01290 2.8e-93 yjlB S Cupin domain
OLHBHBLE_01291 7.1e-66 yjlC S Protein of unknown function (DUF1641)
OLHBHBLE_01292 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
OLHBHBLE_01293 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
OLHBHBLE_01294 5.8e-250 yjmB G symporter YjmB
OLHBHBLE_01295 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
OLHBHBLE_01296 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
OLHBHBLE_01297 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
OLHBHBLE_01298 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_01299 3.7e-227 exuT G Sugar (and other) transporter
OLHBHBLE_01300 2.3e-184 exuR K transcriptional
OLHBHBLE_01301 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
OLHBHBLE_01302 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OLHBHBLE_01303 4.3e-130 MA20_18170 S membrane transporter protein
OLHBHBLE_01304 3.3e-80 yjoA S DinB family
OLHBHBLE_01305 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
OLHBHBLE_01306 2.1e-213 S response regulator aspartate phosphatase
OLHBHBLE_01308 6.3e-41 S YCII-related domain
OLHBHBLE_01309 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
OLHBHBLE_01310 2.1e-61 yjqA S Bacterial PH domain
OLHBHBLE_01311 4.2e-112 yjqB S Pfam:DUF867
OLHBHBLE_01312 4.4e-160 ydbD P Catalase
OLHBHBLE_01313 1.6e-111 xkdA E IrrE N-terminal-like domain
OLHBHBLE_01314 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
OLHBHBLE_01316 5.9e-157 xkdB K sequence-specific DNA binding
OLHBHBLE_01317 6.4e-119 xkdC L Bacterial dnaA protein
OLHBHBLE_01320 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
OLHBHBLE_01321 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OLHBHBLE_01322 4.8e-140 xtmA L phage terminase small subunit
OLHBHBLE_01323 9.6e-255 xtmB S phage terminase, large subunit
OLHBHBLE_01324 5.4e-286 yqbA S portal protein
OLHBHBLE_01325 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OLHBHBLE_01326 5.8e-169 xkdG S Phage capsid family
OLHBHBLE_01327 5.5e-65 yqbG S Protein of unknown function (DUF3199)
OLHBHBLE_01328 8.7e-65 yqbH S Domain of unknown function (DUF3599)
OLHBHBLE_01329 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
OLHBHBLE_01330 1.9e-77 xkdJ
OLHBHBLE_01331 2.5e-256 xkdK S Phage tail sheath C-terminal domain
OLHBHBLE_01332 6.1e-76 xkdM S Phage tail tube protein
OLHBHBLE_01333 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
OLHBHBLE_01334 0.0 xkdO L Transglycosylase SLT domain
OLHBHBLE_01335 3.7e-122 xkdP S Lysin motif
OLHBHBLE_01336 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
OLHBHBLE_01337 2.1e-39 xkdR S Protein of unknown function (DUF2577)
OLHBHBLE_01338 9.6e-71 xkdS S Protein of unknown function (DUF2634)
OLHBHBLE_01339 1.2e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OLHBHBLE_01340 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OLHBHBLE_01341 6.7e-41
OLHBHBLE_01342 0.0
OLHBHBLE_01343 2.6e-55 xkdW S XkdW protein
OLHBHBLE_01344 1.7e-23 xkdX
OLHBHBLE_01345 1.2e-154 xepA
OLHBHBLE_01346 2.8e-39 xhlA S Haemolysin XhlA
OLHBHBLE_01347 9.3e-40 xhlB S SPP1 phage holin
OLHBHBLE_01348 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLHBHBLE_01349 6.7e-23 spoIISB S Stage II sporulation protein SB
OLHBHBLE_01350 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OLHBHBLE_01351 5.8e-175 pit P phosphate transporter
OLHBHBLE_01352 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OLHBHBLE_01353 9.4e-242 steT E amino acid
OLHBHBLE_01354 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
OLHBHBLE_01356 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OLHBHBLE_01357 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLHBHBLE_01359 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OLHBHBLE_01360 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
OLHBHBLE_01361 7.9e-154 dppA E D-aminopeptidase
OLHBHBLE_01362 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLHBHBLE_01363 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OLHBHBLE_01364 3.4e-191 dppD P Belongs to the ABC transporter superfamily
OLHBHBLE_01365 0.0 dppE E ABC transporter substrate-binding protein
OLHBHBLE_01367 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OLHBHBLE_01368 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OLHBHBLE_01369 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OLHBHBLE_01370 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
OLHBHBLE_01371 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
OLHBHBLE_01372 5.3e-161 ykgA E Amidinotransferase
OLHBHBLE_01373 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OLHBHBLE_01374 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OLHBHBLE_01375 1e-07
OLHBHBLE_01376 5.4e-130 ykjA S Protein of unknown function (DUF421)
OLHBHBLE_01377 1e-98 ykkA S Protein of unknown function (DUF664)
OLHBHBLE_01378 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OLHBHBLE_01379 3.5e-55 ykkC P Multidrug resistance protein
OLHBHBLE_01380 2.2e-48 ykkD P Multidrug resistance protein
OLHBHBLE_01381 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OLHBHBLE_01382 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OLHBHBLE_01383 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OLHBHBLE_01384 1.3e-70 ohrA O Organic hydroperoxide resistance protein
OLHBHBLE_01385 3.9e-75 ohrR K COG1846 Transcriptional regulators
OLHBHBLE_01386 8.4e-72 ohrB O Organic hydroperoxide resistance protein
OLHBHBLE_01388 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
OLHBHBLE_01389 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OLHBHBLE_01390 1.7e-176 isp O Belongs to the peptidase S8 family
OLHBHBLE_01391 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLHBHBLE_01392 1.8e-136 ykoC P Cobalt transport protein
OLHBHBLE_01393 4.6e-311 P ABC transporter, ATP-binding protein
OLHBHBLE_01394 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
OLHBHBLE_01395 7.9e-111 ykoF S YKOF-related Family
OLHBHBLE_01396 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_01397 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
OLHBHBLE_01398 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
OLHBHBLE_01399 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
OLHBHBLE_01402 2.2e-222 mgtE P Acts as a magnesium transporter
OLHBHBLE_01403 1.4e-53 tnrA K transcriptional
OLHBHBLE_01404 5.9e-18
OLHBHBLE_01405 6.9e-26 ykoL
OLHBHBLE_01406 1.3e-81 mhqR K transcriptional
OLHBHBLE_01407 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
OLHBHBLE_01408 3.7e-99 ykoP G polysaccharide deacetylase
OLHBHBLE_01409 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
OLHBHBLE_01410 0.0 ykoS
OLHBHBLE_01411 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLHBHBLE_01412 2.3e-262 ligD 6.5.1.1 L ATP-dependent DNA ligase
OLHBHBLE_01413 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OLHBHBLE_01414 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
OLHBHBLE_01415 1.4e-116 ykoX S membrane-associated protein
OLHBHBLE_01416 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OLHBHBLE_01417 4.7e-129 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLHBHBLE_01418 8.2e-117 rsgI S Anti-sigma factor N-terminus
OLHBHBLE_01419 1.9e-26 sspD S small acid-soluble spore protein
OLHBHBLE_01420 1.5e-124 ykrK S Domain of unknown function (DUF1836)
OLHBHBLE_01421 7e-156 htpX O Belongs to the peptidase M48B family
OLHBHBLE_01422 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
OLHBHBLE_01423 1.2e-10 ydfR S Protein of unknown function (DUF421)
OLHBHBLE_01424 4.5e-22 ykzE
OLHBHBLE_01425 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OLHBHBLE_01426 0.0 kinE 2.7.13.3 T Histidine kinase
OLHBHBLE_01427 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OLHBHBLE_01429 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OLHBHBLE_01430 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OLHBHBLE_01431 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OLHBHBLE_01432 8e-232 mtnE 2.6.1.83 E Aminotransferase
OLHBHBLE_01433 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OLHBHBLE_01434 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OLHBHBLE_01435 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OLHBHBLE_01436 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OLHBHBLE_01437 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
OLHBHBLE_01438 6.4e-09 S Spo0E like sporulation regulatory protein
OLHBHBLE_01439 1.4e-64 eag
OLHBHBLE_01440 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
OLHBHBLE_01441 1.3e-75 ykvE K transcriptional
OLHBHBLE_01442 2.5e-125 motB N Flagellar motor protein
OLHBHBLE_01443 2.7e-138 motA N flagellar motor
OLHBHBLE_01444 0.0 clpE O Belongs to the ClpA ClpB family
OLHBHBLE_01445 8.7e-182 ykvI S membrane
OLHBHBLE_01446 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OLHBHBLE_01447 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
OLHBHBLE_01448 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OLHBHBLE_01449 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OLHBHBLE_01450 2e-61 ykvN K Transcriptional regulator
OLHBHBLE_01451 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
OLHBHBLE_01452 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
OLHBHBLE_01453 1.2e-35 3.5.1.104 M LysM domain
OLHBHBLE_01454 8.5e-133 G Glycosyl hydrolases family 18
OLHBHBLE_01455 5.6e-46 ykvR S Protein of unknown function (DUF3219)
OLHBHBLE_01456 6e-25 ykvS S protein conserved in bacteria
OLHBHBLE_01457 2.8e-28
OLHBHBLE_01458 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
OLHBHBLE_01459 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLHBHBLE_01460 4.9e-90 stoA CO thiol-disulfide
OLHBHBLE_01461 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OLHBHBLE_01462 3.8e-09
OLHBHBLE_01463 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OLHBHBLE_01465 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
OLHBHBLE_01467 4.5e-128 glcT K antiterminator
OLHBHBLE_01468 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLHBHBLE_01469 2.1e-39 ptsH G phosphocarrier protein HPr
OLHBHBLE_01470 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OLHBHBLE_01471 7.2e-39 splA S Transcriptional regulator
OLHBHBLE_01472 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
OLHBHBLE_01473 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLHBHBLE_01474 2e-264 mcpC NT chemotaxis protein
OLHBHBLE_01475 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OLHBHBLE_01476 8e-124 ykwD J protein with SCP PR1 domains
OLHBHBLE_01477 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
OLHBHBLE_01478 0.0 pilS 2.7.13.3 T Histidine kinase
OLHBHBLE_01479 8e-224 patA 2.6.1.1 E Aminotransferase
OLHBHBLE_01480 2.2e-15
OLHBHBLE_01481 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
OLHBHBLE_01482 1.7e-84 ykyB S YkyB-like protein
OLHBHBLE_01483 1.6e-238 ykuC EGP Major facilitator Superfamily
OLHBHBLE_01484 4.6e-88 ykuD S protein conserved in bacteria
OLHBHBLE_01485 9.4e-166 ykuE S Metallophosphoesterase
OLHBHBLE_01486 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_01487 0.0 3.2.1.132 M Putative peptidoglycan binding domain
OLHBHBLE_01488 1.7e-93 M Peptidoglycan-binding domain 1 protein
OLHBHBLE_01490 5.2e-234 ykuI T Diguanylate phosphodiesterase
OLHBHBLE_01491 3.9e-37 ykuJ S protein conserved in bacteria
OLHBHBLE_01492 4.4e-94 ykuK S Ribonuclease H-like
OLHBHBLE_01493 3.9e-27 ykzF S Antirepressor AbbA
OLHBHBLE_01494 1.6e-76 ykuL S CBS domain
OLHBHBLE_01495 3.5e-168 ccpC K Transcriptional regulator
OLHBHBLE_01496 5.7e-88 fld C Flavodoxin domain
OLHBHBLE_01497 3.2e-177 ykuO
OLHBHBLE_01498 3.2e-80 fld C Flavodoxin
OLHBHBLE_01499 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OLHBHBLE_01500 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OLHBHBLE_01501 9e-37 ykuS S Belongs to the UPF0180 family
OLHBHBLE_01502 8.8e-142 ykuT M Mechanosensitive ion channel
OLHBHBLE_01503 3.9e-101 ykuU O Alkyl hydroperoxide reductase
OLHBHBLE_01504 4.4e-82 ykuV CO thiol-disulfide
OLHBHBLE_01505 5.8e-95 rok K Repressor of ComK
OLHBHBLE_01506 2.9e-147 yknT
OLHBHBLE_01507 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OLHBHBLE_01508 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OLHBHBLE_01509 8.1e-246 moeA 2.10.1.1 H molybdopterin
OLHBHBLE_01510 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OLHBHBLE_01511 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OLHBHBLE_01512 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OLHBHBLE_01513 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLHBHBLE_01514 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
OLHBHBLE_01515 1e-117 yknW S Yip1 domain
OLHBHBLE_01516 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OLHBHBLE_01517 2.5e-124 macB V ABC transporter, ATP-binding protein
OLHBHBLE_01518 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
OLHBHBLE_01519 3.1e-136 fruR K Transcriptional regulator
OLHBHBLE_01520 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OLHBHBLE_01521 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OLHBHBLE_01522 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OLHBHBLE_01523 8.1e-39 ykoA
OLHBHBLE_01524 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OLHBHBLE_01525 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OLHBHBLE_01526 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OLHBHBLE_01527 1.1e-12 S Uncharacterized protein YkpC
OLHBHBLE_01528 7.7e-183 mreB D Rod-share determining protein MreBH
OLHBHBLE_01529 1.5e-43 abrB K of stationary sporulation gene expression
OLHBHBLE_01530 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OLHBHBLE_01531 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
OLHBHBLE_01532 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
OLHBHBLE_01533 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OLHBHBLE_01534 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OLHBHBLE_01535 8.2e-31 ykzG S Belongs to the UPF0356 family
OLHBHBLE_01536 1.4e-147 ykrA S hydrolases of the HAD superfamily
OLHBHBLE_01537 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OLHBHBLE_01539 2e-115 recN L Putative cell-wall binding lipoprotein
OLHBHBLE_01540 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OLHBHBLE_01541 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OLHBHBLE_01542 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OLHBHBLE_01543 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OLHBHBLE_01544 6.6e-60 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
OLHBHBLE_01545 3.5e-277 speA 4.1.1.19 E Arginine
OLHBHBLE_01546 1.6e-42 yktA S Belongs to the UPF0223 family
OLHBHBLE_01547 7.1e-118 yktB S Belongs to the UPF0637 family
OLHBHBLE_01548 7.1e-26 ykzI
OLHBHBLE_01549 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
OLHBHBLE_01550 6.9e-78 ykzC S Acetyltransferase (GNAT) family
OLHBHBLE_01551 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OLHBHBLE_01552 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
OLHBHBLE_01553 0.0 ylaA
OLHBHBLE_01554 2.7e-42 ylaB
OLHBHBLE_01555 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_01556 1.2e-11 sigC S Putative zinc-finger
OLHBHBLE_01557 1.8e-38 ylaE
OLHBHBLE_01558 8.2e-22 S Family of unknown function (DUF5325)
OLHBHBLE_01559 0.0 typA T GTP-binding protein TypA
OLHBHBLE_01560 4.2e-47 ylaH S YlaH-like protein
OLHBHBLE_01561 2.5e-32 ylaI S protein conserved in bacteria
OLHBHBLE_01562 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OLHBHBLE_01563 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OLHBHBLE_01564 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OLHBHBLE_01565 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
OLHBHBLE_01566 8.7e-44 ylaN S Belongs to the UPF0358 family
OLHBHBLE_01567 4.5e-214 ftsW D Belongs to the SEDS family
OLHBHBLE_01568 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OLHBHBLE_01569 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OLHBHBLE_01570 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OLHBHBLE_01571 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OLHBHBLE_01572 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OLHBHBLE_01573 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OLHBHBLE_01574 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OLHBHBLE_01575 3e-167 ctaG S cytochrome c oxidase
OLHBHBLE_01576 7e-62 ylbA S YugN-like family
OLHBHBLE_01577 2.6e-74 ylbB T COG0517 FOG CBS domain
OLHBHBLE_01578 3e-201 ylbC S protein with SCP PR1 domains
OLHBHBLE_01579 4.1e-63 ylbD S Putative coat protein
OLHBHBLE_01580 6.7e-37 ylbE S YlbE-like protein
OLHBHBLE_01581 1.8e-75 ylbF S Belongs to the UPF0342 family
OLHBHBLE_01582 7.5e-39 ylbG S UPF0298 protein
OLHBHBLE_01583 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
OLHBHBLE_01584 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OLHBHBLE_01585 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
OLHBHBLE_01586 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
OLHBHBLE_01587 6.8e-187 ylbL T Belongs to the peptidase S16 family
OLHBHBLE_01588 2.8e-235 ylbM S Belongs to the UPF0348 family
OLHBHBLE_01590 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
OLHBHBLE_01591 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OLHBHBLE_01592 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OLHBHBLE_01593 4e-89 ylbP K n-acetyltransferase
OLHBHBLE_01594 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OLHBHBLE_01595 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OLHBHBLE_01596 2.9e-78 mraZ K Belongs to the MraZ family
OLHBHBLE_01597 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OLHBHBLE_01598 3.7e-44 ftsL D Essential cell division protein
OLHBHBLE_01599 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OLHBHBLE_01600 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OLHBHBLE_01601 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OLHBHBLE_01602 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OLHBHBLE_01603 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OLHBHBLE_01604 5.7e-186 spoVE D Belongs to the SEDS family
OLHBHBLE_01605 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OLHBHBLE_01606 5.3e-167 murB 1.3.1.98 M cell wall formation
OLHBHBLE_01607 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OLHBHBLE_01608 2.4e-103 ylxW S protein conserved in bacteria
OLHBHBLE_01609 1e-102 ylxX S protein conserved in bacteria
OLHBHBLE_01610 6.2e-58 sbp S small basic protein
OLHBHBLE_01611 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OLHBHBLE_01612 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OLHBHBLE_01613 0.0 bpr O COG1404 Subtilisin-like serine proteases
OLHBHBLE_01614 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OLHBHBLE_01615 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLHBHBLE_01616 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLHBHBLE_01617 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OLHBHBLE_01618 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
OLHBHBLE_01619 2.4e-37 ylmC S sporulation protein
OLHBHBLE_01620 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OLHBHBLE_01621 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OLHBHBLE_01622 3.3e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OLHBHBLE_01623 1.3e-39 yggT S membrane
OLHBHBLE_01624 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OLHBHBLE_01625 2.6e-67 divIVA D Cell division initiation protein
OLHBHBLE_01626 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OLHBHBLE_01627 1.3e-63 dksA T COG1734 DnaK suppressor protein
OLHBHBLE_01628 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OLHBHBLE_01629 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OLHBHBLE_01630 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OLHBHBLE_01631 9e-232 pyrP F Xanthine uracil
OLHBHBLE_01632 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OLHBHBLE_01633 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OLHBHBLE_01634 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OLHBHBLE_01635 0.0 carB 6.3.5.5 F Belongs to the CarB family
OLHBHBLE_01636 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OLHBHBLE_01637 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OLHBHBLE_01638 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OLHBHBLE_01639 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OLHBHBLE_01641 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OLHBHBLE_01642 1.1e-179 cysP P phosphate transporter
OLHBHBLE_01643 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OLHBHBLE_01644 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
OLHBHBLE_01645 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OLHBHBLE_01646 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OLHBHBLE_01647 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OLHBHBLE_01648 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OLHBHBLE_01649 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OLHBHBLE_01650 2.4e-156 yloC S stress-induced protein
OLHBHBLE_01651 1.5e-40 ylzA S Belongs to the UPF0296 family
OLHBHBLE_01652 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OLHBHBLE_01653 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OLHBHBLE_01654 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OLHBHBLE_01655 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OLHBHBLE_01656 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OLHBHBLE_01657 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OLHBHBLE_01658 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OLHBHBLE_01659 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OLHBHBLE_01660 2.4e-141 stp 3.1.3.16 T phosphatase
OLHBHBLE_01661 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OLHBHBLE_01662 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OLHBHBLE_01663 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OLHBHBLE_01664 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
OLHBHBLE_01665 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OLHBHBLE_01666 5.5e-59 asp S protein conserved in bacteria
OLHBHBLE_01667 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
OLHBHBLE_01668 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
OLHBHBLE_01669 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
OLHBHBLE_01670 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OLHBHBLE_01671 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OLHBHBLE_01672 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OLHBHBLE_01673 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OLHBHBLE_01674 6.1e-129 IQ reductase
OLHBHBLE_01675 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OLHBHBLE_01676 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OLHBHBLE_01677 0.0 smc D Required for chromosome condensation and partitioning
OLHBHBLE_01678 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OLHBHBLE_01679 2.9e-87
OLHBHBLE_01680 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OLHBHBLE_01681 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OLHBHBLE_01682 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OLHBHBLE_01683 1.2e-36 ylqC S Belongs to the UPF0109 family
OLHBHBLE_01684 1.3e-61 ylqD S YlqD protein
OLHBHBLE_01685 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OLHBHBLE_01686 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OLHBHBLE_01687 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OLHBHBLE_01688 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OLHBHBLE_01689 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OLHBHBLE_01690 8.5e-291 ylqG
OLHBHBLE_01691 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OLHBHBLE_01692 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OLHBHBLE_01693 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OLHBHBLE_01694 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OLHBHBLE_01695 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OLHBHBLE_01696 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OLHBHBLE_01697 2.5e-169 xerC L tyrosine recombinase XerC
OLHBHBLE_01698 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OLHBHBLE_01699 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OLHBHBLE_01700 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OLHBHBLE_01701 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OLHBHBLE_01702 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
OLHBHBLE_01703 1.9e-31 fliE N Flagellar hook-basal body
OLHBHBLE_01704 2.4e-255 fliF N The M ring may be actively involved in energy transduction
OLHBHBLE_01705 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OLHBHBLE_01706 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OLHBHBLE_01707 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OLHBHBLE_01708 1.5e-69 fliJ N Flagellar biosynthesis chaperone
OLHBHBLE_01709 7.7e-37 ylxF S MgtE intracellular N domain
OLHBHBLE_01710 1.2e-221 fliK N Flagellar hook-length control protein
OLHBHBLE_01711 1.7e-72 flgD N Flagellar basal body rod modification protein
OLHBHBLE_01712 8.2e-140 flgG N Flagellar basal body rod
OLHBHBLE_01713 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
OLHBHBLE_01714 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OLHBHBLE_01715 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OLHBHBLE_01716 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OLHBHBLE_01717 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
OLHBHBLE_01718 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
OLHBHBLE_01719 2.2e-36 fliQ N Role in flagellar biosynthesis
OLHBHBLE_01720 3.6e-132 fliR N Flagellar biosynthetic protein FliR
OLHBHBLE_01721 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OLHBHBLE_01722 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OLHBHBLE_01723 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
OLHBHBLE_01724 7.5e-158 flhG D Belongs to the ParA family
OLHBHBLE_01725 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OLHBHBLE_01726 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OLHBHBLE_01727 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
OLHBHBLE_01728 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OLHBHBLE_01729 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OLHBHBLE_01730 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLHBHBLE_01731 4.3e-78 ylxL
OLHBHBLE_01732 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
OLHBHBLE_01733 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OLHBHBLE_01734 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OLHBHBLE_01735 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OLHBHBLE_01736 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OLHBHBLE_01737 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
OLHBHBLE_01738 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OLHBHBLE_01739 7.7e-233 rasP M zinc metalloprotease
OLHBHBLE_01740 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OLHBHBLE_01741 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OLHBHBLE_01742 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
OLHBHBLE_01743 7.3e-203 nusA K Participates in both transcription termination and antitermination
OLHBHBLE_01744 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
OLHBHBLE_01745 3.1e-47 ylxQ J ribosomal protein
OLHBHBLE_01746 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OLHBHBLE_01747 3e-44 ylxP S protein conserved in bacteria
OLHBHBLE_01748 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OLHBHBLE_01749 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OLHBHBLE_01750 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OLHBHBLE_01751 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OLHBHBLE_01752 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OLHBHBLE_01753 3.2e-172 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OLHBHBLE_01754 4.4e-233 pepR S Belongs to the peptidase M16 family
OLHBHBLE_01755 2.6e-42 ymxH S YlmC YmxH family
OLHBHBLE_01756 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OLHBHBLE_01757 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OLHBHBLE_01758 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OLHBHBLE_01759 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OLHBHBLE_01760 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OLHBHBLE_01761 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OLHBHBLE_01762 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OLHBHBLE_01763 4.4e-32 S YlzJ-like protein
OLHBHBLE_01764 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OLHBHBLE_01765 1.4e-133 ymfC K Transcriptional regulator
OLHBHBLE_01766 3.4e-206 ymfD EGP Major facilitator Superfamily
OLHBHBLE_01767 2.6e-236 ymfF S Peptidase M16
OLHBHBLE_01768 1.4e-242 ymfH S zinc protease
OLHBHBLE_01769 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OLHBHBLE_01770 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
OLHBHBLE_01771 2.4e-76 ymfK S Protein of unknown function (DUF3388)
OLHBHBLE_01772 3.1e-53 ymfK S Protein of unknown function (DUF3388)
OLHBHBLE_01773 1.9e-124 ymfM S protein conserved in bacteria
OLHBHBLE_01774 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OLHBHBLE_01775 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
OLHBHBLE_01776 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OLHBHBLE_01777 1e-215 pbpX V Beta-lactamase
OLHBHBLE_01778 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
OLHBHBLE_01779 1.9e-152 ymdB S protein conserved in bacteria
OLHBHBLE_01780 1.2e-36 spoVS S Stage V sporulation protein S
OLHBHBLE_01781 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OLHBHBLE_01782 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OLHBHBLE_01783 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OLHBHBLE_01784 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OLHBHBLE_01785 2.2e-88 cotE S Spore coat protein
OLHBHBLE_01786 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OLHBHBLE_01787 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OLHBHBLE_01788 2.3e-70 S Regulatory protein YrvL
OLHBHBLE_01790 1.2e-97 ymcC S Membrane
OLHBHBLE_01791 4.4e-109 pksA K Transcriptional regulator
OLHBHBLE_01792 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
OLHBHBLE_01793 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OLHBHBLE_01795 2.4e-186 pksD Q Acyl transferase domain
OLHBHBLE_01796 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OLHBHBLE_01797 1.4e-37 acpK IQ Phosphopantetheine attachment site
OLHBHBLE_01798 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OLHBHBLE_01799 1.3e-245 pksG 2.3.3.10 I synthase
OLHBHBLE_01800 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
OLHBHBLE_01801 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OLHBHBLE_01802 0.0 rhiB IQ polyketide synthase
OLHBHBLE_01803 0.0 pfaA Q Polyketide synthase of type I
OLHBHBLE_01804 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
OLHBHBLE_01805 0.0 dhbF IQ polyketide synthase
OLHBHBLE_01806 0.0 dhbF IQ polyketide synthase
OLHBHBLE_01807 0.0 pks13 HQ Beta-ketoacyl synthase
OLHBHBLE_01808 2.5e-233 cypA C Cytochrome P450
OLHBHBLE_01809 1.2e-61 ymzB
OLHBHBLE_01810 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
OLHBHBLE_01811 4.6e-252 aprX O Belongs to the peptidase S8 family
OLHBHBLE_01812 2.1e-126 ymaC S Replication protein
OLHBHBLE_01813 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
OLHBHBLE_01814 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
OLHBHBLE_01815 4.9e-51 ebrA P Small Multidrug Resistance protein
OLHBHBLE_01817 2.1e-46 ymaF S YmaF family
OLHBHBLE_01818 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OLHBHBLE_01819 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OLHBHBLE_01820 6.3e-23
OLHBHBLE_01821 4.5e-22 ymzA
OLHBHBLE_01822 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OLHBHBLE_01823 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLHBHBLE_01824 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLHBHBLE_01825 2e-109 ymaB
OLHBHBLE_01826 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLHBHBLE_01827 1.7e-176 spoVK O stage V sporulation protein K
OLHBHBLE_01828 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OLHBHBLE_01829 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OLHBHBLE_01830 1.1e-68 glnR K transcriptional
OLHBHBLE_01831 7e-261 glnA 6.3.1.2 E glutamine synthetase
OLHBHBLE_01832 5e-10
OLHBHBLE_01833 2.5e-32
OLHBHBLE_01834 5.8e-39
OLHBHBLE_01835 6.8e-80 G regulation of fungal-type cell wall biogenesis
OLHBHBLE_01836 4.9e-145 ynaC
OLHBHBLE_01837 2e-99 ynaD J Acetyltransferase (GNAT) domain
OLHBHBLE_01838 1.9e-123 ynaE S Domain of unknown function (DUF3885)
OLHBHBLE_01839 6.4e-60 ynaF
OLHBHBLE_01842 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
OLHBHBLE_01843 2.7e-255 xynT G MFS/sugar transport protein
OLHBHBLE_01844 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OLHBHBLE_01845 1e-215 xylR GK ROK family
OLHBHBLE_01846 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OLHBHBLE_01847 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OLHBHBLE_01848 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
OLHBHBLE_01849 3.5e-247 iolT EGP Major facilitator Superfamily
OLHBHBLE_01850 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OLHBHBLE_01851 6.3e-84 yncE S Protein of unknown function (DUF2691)
OLHBHBLE_01852 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OLHBHBLE_01853 5.2e-15
OLHBHBLE_01856 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OLHBHBLE_01858 1.3e-134 S Domain of unknown function, YrpD
OLHBHBLE_01861 7.9e-25 tatA U protein secretion
OLHBHBLE_01862 1.8e-71
OLHBHBLE_01863 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
OLHBHBLE_01866 5.7e-286 gerAA EG Spore germination protein
OLHBHBLE_01867 4.5e-197 gerAB U Spore germination
OLHBHBLE_01868 4.2e-220 gerLC S Spore germination protein
OLHBHBLE_01869 7.7e-154 yndG S DoxX-like family
OLHBHBLE_01870 2.6e-117 yndH S Domain of unknown function (DUF4166)
OLHBHBLE_01871 0.0 yndJ S YndJ-like protein
OLHBHBLE_01873 8.6e-139 yndL S Replication protein
OLHBHBLE_01874 5.8e-74 yndM S Protein of unknown function (DUF2512)
OLHBHBLE_01875 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OLHBHBLE_01877 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OLHBHBLE_01878 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OLHBHBLE_01879 9.2e-113 yneB L resolvase
OLHBHBLE_01880 1.3e-32 ynzC S UPF0291 protein
OLHBHBLE_01881 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OLHBHBLE_01882 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
OLHBHBLE_01883 1.8e-28 yneF S UPF0154 protein
OLHBHBLE_01884 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
OLHBHBLE_01885 7.1e-127 ccdA O cytochrome c biogenesis protein
OLHBHBLE_01886 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OLHBHBLE_01887 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OLHBHBLE_01888 4.2e-74 yneK S Protein of unknown function (DUF2621)
OLHBHBLE_01889 4.1e-65 hspX O Spore coat protein
OLHBHBLE_01890 3.9e-19 sspP S Belongs to the SspP family
OLHBHBLE_01891 2.2e-14 sspO S Belongs to the SspO family
OLHBHBLE_01892 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OLHBHBLE_01893 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OLHBHBLE_01895 3.1e-08 sspN S Small acid-soluble spore protein N family
OLHBHBLE_01896 3.9e-35 tlp S Belongs to the Tlp family
OLHBHBLE_01897 1.2e-73 yneP S Thioesterase-like superfamily
OLHBHBLE_01898 1.3e-53 yneQ
OLHBHBLE_01899 4.1e-49 yneR S Belongs to the HesB IscA family
OLHBHBLE_01900 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OLHBHBLE_01901 6.6e-69 yccU S CoA-binding protein
OLHBHBLE_01902 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OLHBHBLE_01903 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OLHBHBLE_01904 5.9e-43 ynfC
OLHBHBLE_01905 8.2e-252 agcS E Sodium alanine symporter
OLHBHBLE_01906 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
OLHBHBLE_01908 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
OLHBHBLE_01909 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
OLHBHBLE_01910 2.4e-80 yngA S membrane
OLHBHBLE_01911 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OLHBHBLE_01912 5.5e-104 yngC S membrane-associated protein
OLHBHBLE_01913 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
OLHBHBLE_01914 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OLHBHBLE_01915 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OLHBHBLE_01916 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OLHBHBLE_01917 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OLHBHBLE_01918 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OLHBHBLE_01919 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OLHBHBLE_01920 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OLHBHBLE_01921 1.8e-31 S Family of unknown function (DUF5367)
OLHBHBLE_01923 1.3e-306 yngK T Glycosyl hydrolase-like 10
OLHBHBLE_01924 2.8e-64 yngL S Protein of unknown function (DUF1360)
OLHBHBLE_01925 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
OLHBHBLE_01926 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_01927 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_01928 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_01929 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_01930 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OLHBHBLE_01931 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
OLHBHBLE_01932 2.3e-246 yoeA V MATE efflux family protein
OLHBHBLE_01933 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
OLHBHBLE_01935 2.2e-96 L Integrase
OLHBHBLE_01936 3e-34 yoeD G Helix-turn-helix domain
OLHBHBLE_01937 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OLHBHBLE_01938 2.5e-158 gltR1 K Transcriptional regulator
OLHBHBLE_01939 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
OLHBHBLE_01940 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OLHBHBLE_01941 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OLHBHBLE_01942 7.8e-155 gltC K Transcriptional regulator
OLHBHBLE_01943 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OLHBHBLE_01944 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OLHBHBLE_01945 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OLHBHBLE_01946 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_01947 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
OLHBHBLE_01948 3.1e-144 yoxB
OLHBHBLE_01949 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OLHBHBLE_01950 6.2e-235 yoaB EGP Major facilitator Superfamily
OLHBHBLE_01951 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
OLHBHBLE_01952 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OLHBHBLE_01953 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OLHBHBLE_01954 1.9e-33 yoaF
OLHBHBLE_01955 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
OLHBHBLE_01956 7e-14
OLHBHBLE_01957 1.5e-38 S Protein of unknown function (DUF4025)
OLHBHBLE_01958 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
OLHBHBLE_01959 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
OLHBHBLE_01960 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
OLHBHBLE_01961 2.3e-111 yoaK S Membrane
OLHBHBLE_01962 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
OLHBHBLE_01963 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
OLHBHBLE_01965 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
OLHBHBLE_01967 1.5e-146 yoaP 3.1.3.18 K YoaP-like
OLHBHBLE_01968 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
OLHBHBLE_01969 4.1e-89
OLHBHBLE_01970 2.4e-172 yoaR V vancomycin resistance protein
OLHBHBLE_01971 4.3e-75 yoaS S Protein of unknown function (DUF2975)
OLHBHBLE_01972 4.2e-37 yozG K Transcriptional regulator
OLHBHBLE_01973 1.1e-149 yoaT S Protein of unknown function (DUF817)
OLHBHBLE_01974 8.6e-159 yoaU K LysR substrate binding domain
OLHBHBLE_01975 6e-160 yijE EG EamA-like transporter family
OLHBHBLE_01976 3.7e-78 yoaW
OLHBHBLE_01977 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OLHBHBLE_01978 2.3e-170 bla 3.5.2.6 V beta-lactamase
OLHBHBLE_01982 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
OLHBHBLE_01983 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
OLHBHBLE_01984 1.4e-37 S TM2 domain
OLHBHBLE_01985 5.7e-58 K Helix-turn-helix
OLHBHBLE_01987 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
OLHBHBLE_01988 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
OLHBHBLE_01989 1.8e-178 yobF
OLHBHBLE_01994 1.7e-207 S aspartate phosphatase
OLHBHBLE_01996 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OLHBHBLE_01997 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OLHBHBLE_01998 2.6e-38 S YolD-like protein
OLHBHBLE_01999 1.2e-49
OLHBHBLE_02000 0.0 K Psort location Cytoplasmic, score
OLHBHBLE_02001 2.7e-157 yobJ
OLHBHBLE_02002 3e-86 S SMI1-KNR4 cell-wall
OLHBHBLE_02003 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
OLHBHBLE_02004 7.9e-105 yokH G SMI1 / KNR4 family
OLHBHBLE_02005 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
OLHBHBLE_02006 0.0 yobO M Pectate lyase superfamily protein
OLHBHBLE_02007 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
OLHBHBLE_02008 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
OLHBHBLE_02009 2.5e-143 yobR 2.3.1.1 J FR47-like protein
OLHBHBLE_02010 3e-99 yobS K Transcriptional regulator
OLHBHBLE_02011 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
OLHBHBLE_02012 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
OLHBHBLE_02013 9e-178 yobV K WYL domain
OLHBHBLE_02014 2.5e-95 yobW
OLHBHBLE_02015 1e-51 czrA K transcriptional
OLHBHBLE_02016 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OLHBHBLE_02017 1.5e-92 yozB S membrane
OLHBHBLE_02018 2.2e-145
OLHBHBLE_02019 1.9e-94 yocC
OLHBHBLE_02020 6.9e-189 yocD 3.4.17.13 V peptidase S66
OLHBHBLE_02021 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OLHBHBLE_02022 3.2e-198 desK 2.7.13.3 T Histidine kinase
OLHBHBLE_02023 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLHBHBLE_02024 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
OLHBHBLE_02025 0.0 recQ 3.6.4.12 L DNA helicase
OLHBHBLE_02026 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OLHBHBLE_02027 3.3e-83 dksA T general stress protein
OLHBHBLE_02028 6.4e-54 yocL
OLHBHBLE_02029 6.6e-34
OLHBHBLE_02030 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
OLHBHBLE_02031 1.1e-40 yozN
OLHBHBLE_02032 1.9e-36 yocN
OLHBHBLE_02033 4.2e-56 yozO S Bacterial PH domain
OLHBHBLE_02034 2.7e-31 yozC
OLHBHBLE_02035 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OLHBHBLE_02036 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
OLHBHBLE_02037 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
OLHBHBLE_02038 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OLHBHBLE_02039 5.1e-168 yocS S -transporter
OLHBHBLE_02040 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OLHBHBLE_02041 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OLHBHBLE_02042 0.0 yojO P Von Willebrand factor
OLHBHBLE_02043 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
OLHBHBLE_02044 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OLHBHBLE_02045 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OLHBHBLE_02046 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
OLHBHBLE_02047 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OLHBHBLE_02049 4.2e-245 norM V Multidrug efflux pump
OLHBHBLE_02050 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLHBHBLE_02051 2.1e-125 yojG S deacetylase
OLHBHBLE_02052 2.2e-60 yojF S Protein of unknown function (DUF1806)
OLHBHBLE_02053 1.5e-43
OLHBHBLE_02054 3.5e-163 rarD S -transporter
OLHBHBLE_02055 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
OLHBHBLE_02056 3.4e-09
OLHBHBLE_02057 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
OLHBHBLE_02058 3.8e-66 yodA S tautomerase
OLHBHBLE_02059 1.7e-57 yodB K transcriptional
OLHBHBLE_02060 4.8e-108 yodC C nitroreductase
OLHBHBLE_02061 3.8e-113 mhqD S Carboxylesterase
OLHBHBLE_02062 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
OLHBHBLE_02063 6.2e-28 S Protein of unknown function (DUF3311)
OLHBHBLE_02064 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLHBHBLE_02065 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OLHBHBLE_02066 1.7e-128 yodH Q Methyltransferase
OLHBHBLE_02067 5.2e-24 yodI
OLHBHBLE_02068 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OLHBHBLE_02069 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OLHBHBLE_02070 5.3e-09
OLHBHBLE_02071 3.6e-54 yodL S YodL-like
OLHBHBLE_02072 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
OLHBHBLE_02073 2.8e-24 yozD S YozD-like protein
OLHBHBLE_02075 1.4e-124 yodN
OLHBHBLE_02076 1.4e-36 yozE S Belongs to the UPF0346 family
OLHBHBLE_02077 2.9e-47 yokU S YokU-like protein, putative antitoxin
OLHBHBLE_02078 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
OLHBHBLE_02079 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
OLHBHBLE_02080 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
OLHBHBLE_02081 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OLHBHBLE_02082 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OLHBHBLE_02083 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OLHBHBLE_02086 2.9e-145 yiiD K acetyltransferase
OLHBHBLE_02087 1e-256 cgeD M maturation of the outermost layer of the spore
OLHBHBLE_02088 3.5e-38 cgeC
OLHBHBLE_02089 1.2e-65 cgeA
OLHBHBLE_02090 3.3e-188 cgeB S Spore maturation protein
OLHBHBLE_02091 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
OLHBHBLE_02092 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
OLHBHBLE_02094 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OLHBHBLE_02095 1.4e-10 K Cro/C1-type HTH DNA-binding domain
OLHBHBLE_02103 1.9e-168 S Calcineurin-like phosphoesterase
OLHBHBLE_02104 2.5e-30 sspB S spore protein
OLHBHBLE_02109 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
OLHBHBLE_02110 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OLHBHBLE_02111 6.1e-38 O Glutaredoxin
OLHBHBLE_02112 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLHBHBLE_02113 3.3e-97 L HNH endonuclease
OLHBHBLE_02114 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLHBHBLE_02115 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLHBHBLE_02116 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OLHBHBLE_02117 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OLHBHBLE_02134 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
OLHBHBLE_02136 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
OLHBHBLE_02137 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
OLHBHBLE_02142 9.9e-115 DR0488 S protein conserved in bacteria
OLHBHBLE_02143 0.0 2.7.7.7 L DNA polymerase
OLHBHBLE_02144 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OLHBHBLE_02145 1.2e-224 L DNA primase activity
OLHBHBLE_02146 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
OLHBHBLE_02147 1.4e-86
OLHBHBLE_02148 7.6e-180 L AAA domain
OLHBHBLE_02149 1.3e-170
OLHBHBLE_02154 0.0 M Parallel beta-helix repeats
OLHBHBLE_02155 7.7e-149 S Pfam:DUF867
OLHBHBLE_02158 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
OLHBHBLE_02159 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
OLHBHBLE_02160 2.3e-77
OLHBHBLE_02167 1e-44
OLHBHBLE_02169 1.5e-97 S Protein of unknown function (DUF1273)
OLHBHBLE_02171 3e-78 yoqH M LysM domain
OLHBHBLE_02174 8.8e-12 S Protein of unknown function (DUF2815)
OLHBHBLE_02175 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
OLHBHBLE_02186 1.1e-33 K Transcriptional regulator
OLHBHBLE_02187 2.1e-177
OLHBHBLE_02188 6e-263 S DNA-sulfur modification-associated
OLHBHBLE_02189 6.8e-198 L Belongs to the 'phage' integrase family
OLHBHBLE_02194 6.6e-106
OLHBHBLE_02196 1.2e-86
OLHBHBLE_02197 1.1e-96 S Super-infection exclusion protein B
OLHBHBLE_02202 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
OLHBHBLE_02203 3.8e-259
OLHBHBLE_02204 4.6e-35 K Cro/C1-type HTH DNA-binding domain
OLHBHBLE_02205 1.4e-256
OLHBHBLE_02207 5.9e-238
OLHBHBLE_02209 4e-17
OLHBHBLE_02210 5.7e-55 bldD K domain, Protein
OLHBHBLE_02213 0.0
OLHBHBLE_02214 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OLHBHBLE_02216 2.6e-230
OLHBHBLE_02219 1.8e-175
OLHBHBLE_02220 0.0 gp17a S Terminase-like family
OLHBHBLE_02221 6.3e-282
OLHBHBLE_02222 2.1e-266
OLHBHBLE_02223 1.6e-94
OLHBHBLE_02224 5.7e-186
OLHBHBLE_02225 5.1e-81
OLHBHBLE_02226 1.1e-68
OLHBHBLE_02228 1.4e-121
OLHBHBLE_02229 2.6e-91
OLHBHBLE_02230 8.1e-131
OLHBHBLE_02231 1.6e-90
OLHBHBLE_02234 1e-57
OLHBHBLE_02235 1.1e-172
OLHBHBLE_02236 8.1e-07
OLHBHBLE_02237 2.5e-10 xkdX
OLHBHBLE_02238 2.5e-86
OLHBHBLE_02239 6.3e-70
OLHBHBLE_02240 2.1e-193 xerH A Belongs to the 'phage' integrase family
OLHBHBLE_02245 9.3e-116
OLHBHBLE_02246 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OLHBHBLE_02247 6.2e-145 S Phage tail protein
OLHBHBLE_02248 0.0 S Pfam Transposase IS66
OLHBHBLE_02249 6.4e-115
OLHBHBLE_02250 0.0 G Exopolysaccharide biosynthesis protein
OLHBHBLE_02251 6.5e-164
OLHBHBLE_02253 1.6e-186 3.5.1.28 M Ami_2
OLHBHBLE_02254 4.4e-32 bhlA S BhlA holin family
OLHBHBLE_02255 5.5e-40 S SPP1 phage holin
OLHBHBLE_02256 3.4e-74 O protein disulfide oxidoreductase activity
OLHBHBLE_02257 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLHBHBLE_02258 1.2e-70 CO cell redox homeostasis
OLHBHBLE_02259 0.0 V Peptidase C39 family
OLHBHBLE_02262 1.9e-239 S impB/mucB/samB family C-terminal domain
OLHBHBLE_02263 5.8e-55 S YolD-like protein
OLHBHBLE_02264 1.3e-37
OLHBHBLE_02266 6.8e-09 S Domain of unknown function (DUF4879)
OLHBHBLE_02268 2.8e-99 J Acetyltransferase (GNAT) domain
OLHBHBLE_02269 3.2e-109 yokK S SMI1 / KNR4 family
OLHBHBLE_02270 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
OLHBHBLE_02271 1.2e-302 UW nuclease activity
OLHBHBLE_02272 6.7e-92 yokH G SMI1 / KNR4 family
OLHBHBLE_02273 4.1e-203
OLHBHBLE_02274 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
OLHBHBLE_02275 1.1e-83 S Bacterial PH domain
OLHBHBLE_02276 8.4e-156 aacC 2.3.1.81 V aminoglycoside
OLHBHBLE_02279 8.9e-95
OLHBHBLE_02280 1.6e-107
OLHBHBLE_02281 2.7e-307 yokA L Recombinase
OLHBHBLE_02282 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
OLHBHBLE_02283 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OLHBHBLE_02284 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OLHBHBLE_02285 1.6e-70 ypoP K transcriptional
OLHBHBLE_02286 2.6e-223 mepA V MATE efflux family protein
OLHBHBLE_02287 5.5e-29 ypmT S Uncharacterized ympT
OLHBHBLE_02288 5e-99 ypmS S protein conserved in bacteria
OLHBHBLE_02289 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
OLHBHBLE_02290 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OLHBHBLE_02291 3.1e-40 ypmP S Protein of unknown function (DUF2535)
OLHBHBLE_02292 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OLHBHBLE_02293 1.6e-185 pspF K Transcriptional regulator
OLHBHBLE_02294 4.2e-110 hlyIII S protein, Hemolysin III
OLHBHBLE_02295 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OLHBHBLE_02296 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OLHBHBLE_02297 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OLHBHBLE_02298 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OLHBHBLE_02299 7.8e-114 ypjP S YpjP-like protein
OLHBHBLE_02300 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
OLHBHBLE_02301 1.7e-75 yphP S Belongs to the UPF0403 family
OLHBHBLE_02302 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OLHBHBLE_02303 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
OLHBHBLE_02304 3.1e-110 ypgQ S phosphohydrolase
OLHBHBLE_02305 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OLHBHBLE_02306 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OLHBHBLE_02307 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OLHBHBLE_02308 7.9e-31 cspD K Cold-shock protein
OLHBHBLE_02309 3.8e-16 degR
OLHBHBLE_02310 8.1e-31 S Protein of unknown function (DUF2564)
OLHBHBLE_02311 2.6e-27 ypeQ S Zinc-finger
OLHBHBLE_02312 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
OLHBHBLE_02313 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OLHBHBLE_02314 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
OLHBHBLE_02316 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
OLHBHBLE_02317 2e-07
OLHBHBLE_02318 1e-38 ypbS S Protein of unknown function (DUF2533)
OLHBHBLE_02319 0.0 ypbR S Dynamin family
OLHBHBLE_02320 5.1e-87 ypbQ S protein conserved in bacteria
OLHBHBLE_02321 4.4e-208 bcsA Q Naringenin-chalcone synthase
OLHBHBLE_02322 1.6e-228 pbuX F xanthine
OLHBHBLE_02323 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OLHBHBLE_02324 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OLHBHBLE_02325 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
OLHBHBLE_02326 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
OLHBHBLE_02327 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
OLHBHBLE_02328 3.9e-187 ptxS K transcriptional
OLHBHBLE_02329 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OLHBHBLE_02330 5.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_02331 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
OLHBHBLE_02333 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OLHBHBLE_02334 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OLHBHBLE_02335 3.3e-92 ypsA S Belongs to the UPF0398 family
OLHBHBLE_02336 1.3e-237 yprB L RNase_H superfamily
OLHBHBLE_02337 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OLHBHBLE_02338 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OLHBHBLE_02339 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
OLHBHBLE_02340 1.2e-48 yppG S YppG-like protein
OLHBHBLE_02342 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
OLHBHBLE_02345 2.6e-188 yppC S Protein of unknown function (DUF2515)
OLHBHBLE_02346 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OLHBHBLE_02347 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
OLHBHBLE_02348 4.7e-93 ypoC
OLHBHBLE_02349 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OLHBHBLE_02350 5.7e-129 dnaD L DNA replication protein DnaD
OLHBHBLE_02351 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
OLHBHBLE_02352 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OLHBHBLE_02353 3.4e-80 ypmB S protein conserved in bacteria
OLHBHBLE_02354 6.7e-23 ypmA S Protein of unknown function (DUF4264)
OLHBHBLE_02355 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OLHBHBLE_02356 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OLHBHBLE_02357 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OLHBHBLE_02358 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OLHBHBLE_02359 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OLHBHBLE_02360 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OLHBHBLE_02361 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OLHBHBLE_02362 6.9e-130 bshB1 S proteins, LmbE homologs
OLHBHBLE_02363 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OLHBHBLE_02364 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OLHBHBLE_02365 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OLHBHBLE_02366 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OLHBHBLE_02367 6.1e-143 ypjB S sporulation protein
OLHBHBLE_02368 4.4e-98 ypjA S membrane
OLHBHBLE_02369 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OLHBHBLE_02370 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
OLHBHBLE_02371 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
OLHBHBLE_02372 8.5e-78 ypiF S Protein of unknown function (DUF2487)
OLHBHBLE_02373 2.8e-99 ypiB S Belongs to the UPF0302 family
OLHBHBLE_02374 4.1e-234 S COG0457 FOG TPR repeat
OLHBHBLE_02375 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OLHBHBLE_02376 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OLHBHBLE_02377 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OLHBHBLE_02378 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OLHBHBLE_02379 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OLHBHBLE_02380 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
OLHBHBLE_02381 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OLHBHBLE_02382 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OLHBHBLE_02383 3.4e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OLHBHBLE_02384 4.6e-64 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OLHBHBLE_02385 1.7e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OLHBHBLE_02386 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OLHBHBLE_02387 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OLHBHBLE_02388 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OLHBHBLE_02389 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OLHBHBLE_02390 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OLHBHBLE_02391 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OLHBHBLE_02392 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OLHBHBLE_02393 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
OLHBHBLE_02394 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OLHBHBLE_02395 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OLHBHBLE_02396 5.4e-138 yphF
OLHBHBLE_02397 1.6e-18 yphE S Protein of unknown function (DUF2768)
OLHBHBLE_02398 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OLHBHBLE_02399 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OLHBHBLE_02400 1.6e-28 ypzH
OLHBHBLE_02401 2.5e-161 seaA S YIEGIA protein
OLHBHBLE_02402 1.3e-102 yphA
OLHBHBLE_02403 1e-07 S YpzI-like protein
OLHBHBLE_02404 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OLHBHBLE_02405 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
OLHBHBLE_02406 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OLHBHBLE_02407 1.8e-23 S Family of unknown function (DUF5359)
OLHBHBLE_02408 9.2e-113 ypfA M Flagellar protein YcgR
OLHBHBLE_02409 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OLHBHBLE_02410 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OLHBHBLE_02411 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
OLHBHBLE_02412 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OLHBHBLE_02413 7.3e-247 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OLHBHBLE_02414 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OLHBHBLE_02415 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
OLHBHBLE_02416 2.8e-81 ypbF S Protein of unknown function (DUF2663)
OLHBHBLE_02417 4.6e-81 ypbE M Lysin motif
OLHBHBLE_02418 2.2e-100 ypbD S metal-dependent membrane protease
OLHBHBLE_02419 3.2e-286 recQ 3.6.4.12 L DNA helicase
OLHBHBLE_02420 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
OLHBHBLE_02421 4.7e-41 fer C Ferredoxin
OLHBHBLE_02422 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OLHBHBLE_02423 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OLHBHBLE_02424 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OLHBHBLE_02425 6.8e-201 rsiX
OLHBHBLE_02426 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_02427 0.0 resE 2.7.13.3 T Histidine kinase
OLHBHBLE_02428 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_02429 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OLHBHBLE_02430 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OLHBHBLE_02431 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OLHBHBLE_02432 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OLHBHBLE_02433 1.9e-87 spmB S Spore maturation protein
OLHBHBLE_02434 3.5e-103 spmA S Spore maturation protein
OLHBHBLE_02435 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OLHBHBLE_02436 4e-98 ypuI S Protein of unknown function (DUF3907)
OLHBHBLE_02437 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OLHBHBLE_02438 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OLHBHBLE_02439 4.5e-94 ypuF S Domain of unknown function (DUF309)
OLHBHBLE_02440 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLHBHBLE_02441 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OLHBHBLE_02442 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OLHBHBLE_02443 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
OLHBHBLE_02444 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OLHBHBLE_02445 6e-55 ypuD
OLHBHBLE_02446 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OLHBHBLE_02447 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
OLHBHBLE_02448 1.5e-17 S SNARE associated Golgi protein
OLHBHBLE_02451 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OLHBHBLE_02452 1.3e-149 ypuA S Secreted protein
OLHBHBLE_02453 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OLHBHBLE_02454 1.4e-273 spoVAF EG Stage V sporulation protein AF
OLHBHBLE_02455 1.4e-110 spoVAEA S stage V sporulation protein
OLHBHBLE_02456 2.2e-57 spoVAEB S stage V sporulation protein
OLHBHBLE_02457 9e-192 spoVAD I Stage V sporulation protein AD
OLHBHBLE_02458 2.3e-78 spoVAC S stage V sporulation protein AC
OLHBHBLE_02459 1e-67 spoVAB S Stage V sporulation protein AB
OLHBHBLE_02460 7.4e-112 spoVAA S Stage V sporulation protein AA
OLHBHBLE_02461 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLHBHBLE_02462 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OLHBHBLE_02463 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OLHBHBLE_02464 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OLHBHBLE_02465 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OLHBHBLE_02466 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OLHBHBLE_02467 2.6e-166 xerD L recombinase XerD
OLHBHBLE_02468 3.7e-37 S Protein of unknown function (DUF4227)
OLHBHBLE_02469 2.4e-80 fur P Belongs to the Fur family
OLHBHBLE_02470 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OLHBHBLE_02471 2e-32 yqkK
OLHBHBLE_02472 5.5e-242 mleA 1.1.1.38 C malic enzyme
OLHBHBLE_02473 3.1e-235 mleN C Na H antiporter
OLHBHBLE_02474 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
OLHBHBLE_02475 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
OLHBHBLE_02476 4.5e-58 ansR K Transcriptional regulator
OLHBHBLE_02477 3e-223 yqxK 3.6.4.12 L DNA helicase
OLHBHBLE_02478 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OLHBHBLE_02480 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OLHBHBLE_02481 4e-14 yqkE S Protein of unknown function (DUF3886)
OLHBHBLE_02482 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OLHBHBLE_02483 9.4e-39 yqkC S Protein of unknown function (DUF2552)
OLHBHBLE_02484 2.8e-54 yqkB S Belongs to the HesB IscA family
OLHBHBLE_02485 4.7e-196 yqkA K GrpB protein
OLHBHBLE_02486 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
OLHBHBLE_02487 3.6e-87 yqjY K acetyltransferase
OLHBHBLE_02488 2.2e-49 S YolD-like protein
OLHBHBLE_02489 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OLHBHBLE_02491 5.2e-226 yqjV G Major Facilitator Superfamily
OLHBHBLE_02493 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLHBHBLE_02494 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
OLHBHBLE_02495 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OLHBHBLE_02496 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_02497 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
OLHBHBLE_02498 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OLHBHBLE_02499 0.0 rocB E arginine degradation protein
OLHBHBLE_02500 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OLHBHBLE_02501 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OLHBHBLE_02502 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OLHBHBLE_02503 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OLHBHBLE_02504 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OLHBHBLE_02505 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OLHBHBLE_02506 4.5e-24 yqzJ
OLHBHBLE_02507 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OLHBHBLE_02508 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
OLHBHBLE_02509 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OLHBHBLE_02510 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OLHBHBLE_02511 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
OLHBHBLE_02513 1.4e-98 yqjB S protein conserved in bacteria
OLHBHBLE_02514 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
OLHBHBLE_02515 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OLHBHBLE_02516 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
OLHBHBLE_02517 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
OLHBHBLE_02518 9.3e-77 yqiW S Belongs to the UPF0403 family
OLHBHBLE_02519 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OLHBHBLE_02520 7.9e-208 norA EGP Major facilitator Superfamily
OLHBHBLE_02521 2.6e-152 bmrR K helix_turn_helix, mercury resistance
OLHBHBLE_02522 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OLHBHBLE_02523 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OLHBHBLE_02524 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OLHBHBLE_02525 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OLHBHBLE_02526 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
OLHBHBLE_02527 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OLHBHBLE_02528 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
OLHBHBLE_02529 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
OLHBHBLE_02530 4e-34 yqzF S Protein of unknown function (DUF2627)
OLHBHBLE_02531 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OLHBHBLE_02532 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OLHBHBLE_02533 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OLHBHBLE_02534 1.8e-212 mmgC I acyl-CoA dehydrogenase
OLHBHBLE_02535 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
OLHBHBLE_02536 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
OLHBHBLE_02537 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OLHBHBLE_02538 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
OLHBHBLE_02539 5.9e-27
OLHBHBLE_02540 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OLHBHBLE_02542 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OLHBHBLE_02543 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
OLHBHBLE_02544 0.0 recN L May be involved in recombinational repair of damaged DNA
OLHBHBLE_02545 1.7e-78 argR K Regulates arginine biosynthesis genes
OLHBHBLE_02546 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OLHBHBLE_02547 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OLHBHBLE_02548 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OLHBHBLE_02549 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OLHBHBLE_02550 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OLHBHBLE_02551 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OLHBHBLE_02552 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OLHBHBLE_02553 2.1e-67 yqhY S protein conserved in bacteria
OLHBHBLE_02554 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OLHBHBLE_02555 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OLHBHBLE_02556 9.9e-91 spoIIIAH S SpoIIIAH-like protein
OLHBHBLE_02557 6.9e-103 spoIIIAG S stage III sporulation protein AG
OLHBHBLE_02558 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OLHBHBLE_02559 1.3e-197 spoIIIAE S stage III sporulation protein AE
OLHBHBLE_02560 2.3e-58 spoIIIAD S Stage III sporulation protein AD
OLHBHBLE_02561 7.6e-29 spoIIIAC S stage III sporulation protein AC
OLHBHBLE_02562 2.9e-85 spoIIIAB S Stage III sporulation protein
OLHBHBLE_02563 1.2e-171 spoIIIAA S stage III sporulation protein AA
OLHBHBLE_02564 7.9e-37 yqhV S Protein of unknown function (DUF2619)
OLHBHBLE_02565 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OLHBHBLE_02566 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OLHBHBLE_02567 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
OLHBHBLE_02568 2.3e-93 yqhR S Conserved membrane protein YqhR
OLHBHBLE_02569 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
OLHBHBLE_02570 2.2e-61 yqhP
OLHBHBLE_02571 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
OLHBHBLE_02572 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OLHBHBLE_02573 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OLHBHBLE_02574 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
OLHBHBLE_02575 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OLHBHBLE_02576 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OLHBHBLE_02577 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OLHBHBLE_02578 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OLHBHBLE_02579 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
OLHBHBLE_02580 1.2e-24 sinI S Anti-repressor SinI
OLHBHBLE_02581 1e-54 sinR K transcriptional
OLHBHBLE_02582 2.3e-142 tasA S Cell division protein FtsN
OLHBHBLE_02583 6.7e-59 sipW 3.4.21.89 U Signal peptidase
OLHBHBLE_02584 2.1e-116 yqxM
OLHBHBLE_02585 7.3e-54 yqzG S Protein of unknown function (DUF3889)
OLHBHBLE_02586 1.4e-26 yqzE S YqzE-like protein
OLHBHBLE_02587 3.7e-42 S ComG operon protein 7
OLHBHBLE_02588 5.5e-49 comGF U Putative Competence protein ComGF
OLHBHBLE_02589 1.1e-59 comGE
OLHBHBLE_02590 4.4e-71 gspH NU protein transport across the cell outer membrane
OLHBHBLE_02591 1.4e-47 comGC U Required for transformation and DNA binding
OLHBHBLE_02592 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
OLHBHBLE_02593 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OLHBHBLE_02595 7.2e-175 corA P Mg2 transporter protein
OLHBHBLE_02596 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OLHBHBLE_02597 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OLHBHBLE_02599 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
OLHBHBLE_02600 1.8e-37 yqgY S Protein of unknown function (DUF2626)
OLHBHBLE_02601 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OLHBHBLE_02602 8.9e-23 yqgW S Protein of unknown function (DUF2759)
OLHBHBLE_02603 6.9e-50 yqgV S Thiamine-binding protein
OLHBHBLE_02604 2.7e-199 yqgU
OLHBHBLE_02605 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
OLHBHBLE_02606 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OLHBHBLE_02607 5.2e-181 glcK 2.7.1.2 G Glucokinase
OLHBHBLE_02608 3.1e-33 yqgQ S Protein conserved in bacteria
OLHBHBLE_02609 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
OLHBHBLE_02610 2.5e-09 yqgO
OLHBHBLE_02611 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OLHBHBLE_02612 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OLHBHBLE_02613 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
OLHBHBLE_02615 9.2e-51 yqzD
OLHBHBLE_02616 1.9e-75 yqzC S YceG-like family
OLHBHBLE_02617 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OLHBHBLE_02618 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OLHBHBLE_02619 4.4e-158 pstA P Phosphate transport system permease
OLHBHBLE_02620 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
OLHBHBLE_02621 5.3e-151 pstS P Phosphate
OLHBHBLE_02622 0.0 pbpA 3.4.16.4 M penicillin-binding protein
OLHBHBLE_02623 2.5e-231 yqgE EGP Major facilitator superfamily
OLHBHBLE_02624 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OLHBHBLE_02625 4e-73 yqgC S protein conserved in bacteria
OLHBHBLE_02626 8.5e-134 yqgB S Protein of unknown function (DUF1189)
OLHBHBLE_02627 2.2e-75 yqgA
OLHBHBLE_02628 5.2e-47 yqfZ M LysM domain
OLHBHBLE_02629 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OLHBHBLE_02630 4.3e-62 yqfX S membrane
OLHBHBLE_02631 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OLHBHBLE_02632 1.9e-77 zur P Belongs to the Fur family
OLHBHBLE_02633 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OLHBHBLE_02634 2.1e-36 yqfT S Protein of unknown function (DUF2624)
OLHBHBLE_02635 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OLHBHBLE_02636 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OLHBHBLE_02637 2.9e-14 yqfQ S YqfQ-like protein
OLHBHBLE_02638 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OLHBHBLE_02639 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OLHBHBLE_02640 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
OLHBHBLE_02641 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
OLHBHBLE_02642 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OLHBHBLE_02643 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OLHBHBLE_02644 4.5e-88 yaiI S Belongs to the UPF0178 family
OLHBHBLE_02645 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OLHBHBLE_02646 4.5e-112 ccpN K CBS domain
OLHBHBLE_02647 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OLHBHBLE_02648 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OLHBHBLE_02649 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
OLHBHBLE_02650 8.4e-19 S YqzL-like protein
OLHBHBLE_02651 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OLHBHBLE_02652 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OLHBHBLE_02653 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OLHBHBLE_02654 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OLHBHBLE_02655 0.0 yqfF S membrane-associated HD superfamily hydrolase
OLHBHBLE_02657 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
OLHBHBLE_02658 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OLHBHBLE_02659 2.7e-45 yqfC S sporulation protein YqfC
OLHBHBLE_02660 6e-25 yqfB
OLHBHBLE_02661 4.3e-122 yqfA S UPF0365 protein
OLHBHBLE_02662 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
OLHBHBLE_02663 2.5e-61 yqeY S Yqey-like protein
OLHBHBLE_02664 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OLHBHBLE_02665 1.6e-158 yqeW P COG1283 Na phosphate symporter
OLHBHBLE_02666 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OLHBHBLE_02667 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OLHBHBLE_02668 5.4e-175 prmA J Methylates ribosomal protein L11
OLHBHBLE_02669 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OLHBHBLE_02670 0.0 dnaK O Heat shock 70 kDa protein
OLHBHBLE_02671 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OLHBHBLE_02672 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OLHBHBLE_02673 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
OLHBHBLE_02674 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OLHBHBLE_02675 1e-54 yqxA S Protein of unknown function (DUF3679)
OLHBHBLE_02676 6.9e-223 spoIIP M stage II sporulation protein P
OLHBHBLE_02677 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OLHBHBLE_02678 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
OLHBHBLE_02679 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
OLHBHBLE_02680 4.1e-15 S YqzM-like protein
OLHBHBLE_02681 0.0 comEC S Competence protein ComEC
OLHBHBLE_02682 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
OLHBHBLE_02683 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
OLHBHBLE_02684 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OLHBHBLE_02685 2.9e-139 yqeM Q Methyltransferase
OLHBHBLE_02686 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OLHBHBLE_02687 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OLHBHBLE_02688 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OLHBHBLE_02689 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OLHBHBLE_02690 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OLHBHBLE_02691 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OLHBHBLE_02692 5.3e-95 yqeG S hydrolase of the HAD superfamily
OLHBHBLE_02694 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
OLHBHBLE_02695 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLHBHBLE_02696 4.7e-106 yqeD S SNARE associated Golgi protein
OLHBHBLE_02697 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
OLHBHBLE_02698 2.3e-133 yqeB
OLHBHBLE_02699 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
OLHBHBLE_02700 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLHBHBLE_02701 1.4e-281 cisA2 L Recombinase
OLHBHBLE_02702 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
OLHBHBLE_02703 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
OLHBHBLE_02704 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLHBHBLE_02705 1.6e-54 arsR K ArsR family transcriptional regulator
OLHBHBLE_02706 1.1e-152 yqcI S YqcI/YcgG family
OLHBHBLE_02707 1.6e-96 S Tetratricopeptide repeat
OLHBHBLE_02710 3.8e-277 A Pre-toxin TG
OLHBHBLE_02711 1.1e-104 S Suppressor of fused protein (SUFU)
OLHBHBLE_02713 5e-60
OLHBHBLE_02715 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OLHBHBLE_02716 2.6e-68 S Bacteriophage holin family
OLHBHBLE_02717 4.8e-165 xepA
OLHBHBLE_02718 1.3e-23
OLHBHBLE_02719 4.1e-56 xkdW S XkdW protein
OLHBHBLE_02720 2e-221
OLHBHBLE_02721 9.6e-40
OLHBHBLE_02722 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OLHBHBLE_02723 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OLHBHBLE_02724 9.6e-71 xkdS S Protein of unknown function (DUF2634)
OLHBHBLE_02725 1.8e-38 xkdR S Protein of unknown function (DUF2577)
OLHBHBLE_02726 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
OLHBHBLE_02727 9e-114 xkdP S Lysin motif
OLHBHBLE_02728 0.0 xkdO L Transglycosylase SLT domain
OLHBHBLE_02729 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
OLHBHBLE_02731 3.6e-76 xkdM S Phage tail tube protein
OLHBHBLE_02732 5.5e-256 xkdK S Phage tail sheath C-terminal domain
OLHBHBLE_02733 3.2e-26
OLHBHBLE_02734 1.4e-77
OLHBHBLE_02735 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
OLHBHBLE_02736 6.7e-65 yqbH S Domain of unknown function (DUF3599)
OLHBHBLE_02737 2.1e-67 S Protein of unknown function (DUF3199)
OLHBHBLE_02738 3.6e-51 S YqbF, hypothetical protein domain
OLHBHBLE_02739 1.9e-167 xkdG S Phage capsid family
OLHBHBLE_02740 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
OLHBHBLE_02741 2e-115
OLHBHBLE_02742 5.7e-169 S Phage Mu protein F like protein
OLHBHBLE_02743 5.9e-296 yqbA S portal protein
OLHBHBLE_02744 2.4e-253 S phage terminase, large subunit
OLHBHBLE_02745 6.3e-107 yqaS L DNA packaging
OLHBHBLE_02747 6.5e-81 L Transposase
OLHBHBLE_02748 1.6e-166
OLHBHBLE_02749 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
OLHBHBLE_02750 7.2e-74 rusA L Endodeoxyribonuclease RusA
OLHBHBLE_02752 5.9e-168 xkdC L IstB-like ATP binding protein
OLHBHBLE_02753 4.7e-123 3.1.3.16 L DnaD domain protein
OLHBHBLE_02754 2.5e-155 recT L RecT family
OLHBHBLE_02755 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
OLHBHBLE_02759 1.2e-103
OLHBHBLE_02761 6.5e-37 K Helix-turn-helix XRE-family like proteins
OLHBHBLE_02762 1.1e-56 K sequence-specific DNA binding
OLHBHBLE_02764 1e-101 adk 2.7.4.3 F adenylate kinase activity
OLHBHBLE_02765 1.4e-100 yqaB E IrrE N-terminal-like domain
OLHBHBLE_02766 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OLHBHBLE_02767 2e-68 psiE S Protein PsiE homolog
OLHBHBLE_02768 9e-237 yrkQ T Histidine kinase
OLHBHBLE_02769 1.1e-127 T Transcriptional regulator
OLHBHBLE_02770 8.2e-224 yrkO P Protein of unknown function (DUF418)
OLHBHBLE_02771 6e-105 yrkN K Acetyltransferase (GNAT) family
OLHBHBLE_02772 1.5e-97 ywrO S Flavodoxin-like fold
OLHBHBLE_02773 2.8e-79 S Protein of unknown function with HXXEE motif
OLHBHBLE_02774 4.3e-117 yrkJ S membrane transporter protein
OLHBHBLE_02775 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
OLHBHBLE_02776 1.1e-219 yrkH P Rhodanese Homology Domain
OLHBHBLE_02777 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
OLHBHBLE_02778 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
OLHBHBLE_02779 7.8e-39 yrkD S protein conserved in bacteria
OLHBHBLE_02780 2.6e-108 yrkC G Cupin domain
OLHBHBLE_02781 4.8e-151 bltR K helix_turn_helix, mercury resistance
OLHBHBLE_02782 3.5e-211 blt EGP Major facilitator Superfamily
OLHBHBLE_02783 1.4e-83 bltD 2.3.1.57 K FR47-like protein
OLHBHBLE_02784 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OLHBHBLE_02785 2.1e-17 S YrzO-like protein
OLHBHBLE_02786 1.7e-171 yrdR EG EamA-like transporter family
OLHBHBLE_02787 5.9e-160 yrdQ K Transcriptional regulator
OLHBHBLE_02788 2e-199 trkA P Oxidoreductase
OLHBHBLE_02789 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
OLHBHBLE_02790 1.3e-66 yodA S tautomerase
OLHBHBLE_02791 7.7e-163 gltR K LysR substrate binding domain
OLHBHBLE_02793 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
OLHBHBLE_02794 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
OLHBHBLE_02795 3.3e-138 azlC E AzlC protein
OLHBHBLE_02796 2.2e-79 bkdR K helix_turn_helix ASNC type
OLHBHBLE_02797 4.1e-46 yrdF K ribonuclease inhibitor
OLHBHBLE_02798 4.1e-231 cypA C Cytochrome P450
OLHBHBLE_02800 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
OLHBHBLE_02801 1.9e-57 S Protein of unknown function (DUF2568)
OLHBHBLE_02802 1.2e-91 yrdA S DinB family
OLHBHBLE_02803 7.6e-168 aadK G Streptomycin adenylyltransferase
OLHBHBLE_02804 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OLHBHBLE_02805 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OLHBHBLE_02806 3e-125 yrpD S Domain of unknown function, YrpD
OLHBHBLE_02808 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
OLHBHBLE_02809 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_02810 4.5e-188 yrpG C Aldo/keto reductase family
OLHBHBLE_02811 9.5e-226 yraO C Citrate transporter
OLHBHBLE_02812 1.2e-163 yraN K Transcriptional regulator
OLHBHBLE_02813 2.4e-206 yraM S PrpF protein
OLHBHBLE_02815 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OLHBHBLE_02816 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLHBHBLE_02817 3.2e-155 S Alpha beta hydrolase
OLHBHBLE_02818 1.7e-60 T sh3 domain protein
OLHBHBLE_02819 2.4e-61 T sh3 domain protein
OLHBHBLE_02820 1.3e-66 E Glyoxalase-like domain
OLHBHBLE_02821 5.3e-37 yraG
OLHBHBLE_02822 6.4e-63 yraF M Spore coat protein
OLHBHBLE_02823 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OLHBHBLE_02824 2.6e-26 yraE
OLHBHBLE_02825 1.1e-49 yraD M Spore coat protein
OLHBHBLE_02826 4.3e-47 yraB K helix_turn_helix, mercury resistance
OLHBHBLE_02827 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
OLHBHBLE_02828 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
OLHBHBLE_02829 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
OLHBHBLE_02830 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
OLHBHBLE_02831 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
OLHBHBLE_02832 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
OLHBHBLE_02833 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
OLHBHBLE_02834 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
OLHBHBLE_02835 0.0 levR K PTS system fructose IIA component
OLHBHBLE_02836 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
OLHBHBLE_02837 3.6e-106 yrhP E LysE type translocator
OLHBHBLE_02838 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
OLHBHBLE_02839 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_02840 1.7e-151 rsiV S Protein of unknown function (DUF3298)
OLHBHBLE_02841 0.0 yrhL I Acyltransferase family
OLHBHBLE_02842 1.5e-46 yrhK S YrhK-like protein
OLHBHBLE_02843 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OLHBHBLE_02844 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
OLHBHBLE_02845 4.5e-97 yrhH Q methyltransferase
OLHBHBLE_02848 1.8e-142 focA P Formate nitrite
OLHBHBLE_02849 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
OLHBHBLE_02850 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
OLHBHBLE_02851 1.4e-78 yrhD S Protein of unknown function (DUF1641)
OLHBHBLE_02852 4.6e-35 yrhC S YrhC-like protein
OLHBHBLE_02853 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OLHBHBLE_02854 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OLHBHBLE_02855 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OLHBHBLE_02856 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OLHBHBLE_02857 7e-27 yrzA S Protein of unknown function (DUF2536)
OLHBHBLE_02858 4.2e-63 yrrS S Protein of unknown function (DUF1510)
OLHBHBLE_02859 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
OLHBHBLE_02860 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OLHBHBLE_02861 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
OLHBHBLE_02862 2.7e-246 yegQ O COG0826 Collagenase and related proteases
OLHBHBLE_02863 7.8e-174 yegQ O Peptidase U32
OLHBHBLE_02864 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
OLHBHBLE_02865 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OLHBHBLE_02866 1.2e-45 yrzB S Belongs to the UPF0473 family
OLHBHBLE_02867 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OLHBHBLE_02868 1.7e-41 yrzL S Belongs to the UPF0297 family
OLHBHBLE_02869 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OLHBHBLE_02870 2.7e-170 yrrI S AI-2E family transporter
OLHBHBLE_02871 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OLHBHBLE_02872 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
OLHBHBLE_02873 3.6e-109 gluC P ABC transporter
OLHBHBLE_02874 7.6e-107 glnP P ABC transporter
OLHBHBLE_02875 8e-08 S Protein of unknown function (DUF3918)
OLHBHBLE_02876 9.8e-31 yrzR
OLHBHBLE_02877 1.8e-83 yrrD S protein conserved in bacteria
OLHBHBLE_02878 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OLHBHBLE_02879 1.4e-15 S COG0457 FOG TPR repeat
OLHBHBLE_02880 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OLHBHBLE_02881 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
OLHBHBLE_02882 1.2e-70 cymR K Transcriptional regulator
OLHBHBLE_02883 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OLHBHBLE_02884 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OLHBHBLE_02885 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OLHBHBLE_02886 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
OLHBHBLE_02888 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
OLHBHBLE_02889 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OLHBHBLE_02890 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OLHBHBLE_02891 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OLHBHBLE_02892 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
OLHBHBLE_02893 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
OLHBHBLE_02894 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
OLHBHBLE_02895 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OLHBHBLE_02896 9.4e-49 yrzD S Post-transcriptional regulator
OLHBHBLE_02897 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLHBHBLE_02898 2.2e-114 yrbG S membrane
OLHBHBLE_02899 1.2e-74 yrzE S Protein of unknown function (DUF3792)
OLHBHBLE_02900 1.1e-38 yajC U Preprotein translocase subunit YajC
OLHBHBLE_02901 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OLHBHBLE_02902 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OLHBHBLE_02903 2.6e-18 yrzS S Protein of unknown function (DUF2905)
OLHBHBLE_02904 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OLHBHBLE_02905 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OLHBHBLE_02906 4.8e-93 bofC S BofC C-terminal domain
OLHBHBLE_02907 5.3e-253 csbX EGP Major facilitator Superfamily
OLHBHBLE_02908 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
OLHBHBLE_02909 6.5e-119 yrzF T serine threonine protein kinase
OLHBHBLE_02911 2.6e-35 S Family of unknown function (DUF5412)
OLHBHBLE_02912 1.8e-262 alsT E Sodium alanine symporter
OLHBHBLE_02913 1.9e-127 yebC K transcriptional regulatory protein
OLHBHBLE_02914 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OLHBHBLE_02915 9.8e-158 safA M spore coat assembly protein SafA
OLHBHBLE_02916 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OLHBHBLE_02917 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OLHBHBLE_02918 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OLHBHBLE_02919 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
OLHBHBLE_02920 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
OLHBHBLE_02921 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
OLHBHBLE_02922 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
OLHBHBLE_02923 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OLHBHBLE_02924 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OLHBHBLE_02925 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OLHBHBLE_02926 4.1e-56 ysxB J ribosomal protein
OLHBHBLE_02927 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
OLHBHBLE_02928 9.2e-161 spoIVFB S Stage IV sporulation protein
OLHBHBLE_02929 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OLHBHBLE_02930 2.5e-144 minD D Belongs to the ParA family
OLHBHBLE_02931 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OLHBHBLE_02932 1.4e-84 mreD M shape-determining protein
OLHBHBLE_02933 2.8e-157 mreC M Involved in formation and maintenance of cell shape
OLHBHBLE_02934 1.8e-184 mreB D Rod shape-determining protein MreB
OLHBHBLE_02935 5.9e-126 radC E Belongs to the UPF0758 family
OLHBHBLE_02936 2.8e-102 maf D septum formation protein Maf
OLHBHBLE_02937 1.1e-168 spoIIB S Sporulation related domain
OLHBHBLE_02938 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OLHBHBLE_02939 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OLHBHBLE_02940 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OLHBHBLE_02941 1.6e-25
OLHBHBLE_02942 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OLHBHBLE_02943 1.9e-226 spoVID M stage VI sporulation protein D
OLHBHBLE_02944 9.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OLHBHBLE_02945 1.1e-181 hemB 4.2.1.24 H Belongs to the ALAD family
OLHBHBLE_02946 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OLHBHBLE_02947 5.7e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OLHBHBLE_02948 3.6e-146 hemX O cytochrome C
OLHBHBLE_02949 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OLHBHBLE_02950 5.4e-89 ysxD
OLHBHBLE_02951 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
OLHBHBLE_02952 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OLHBHBLE_02953 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OLHBHBLE_02954 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OLHBHBLE_02955 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OLHBHBLE_02956 1.9e-186 ysoA H Tetratricopeptide repeat
OLHBHBLE_02957 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OLHBHBLE_02958 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OLHBHBLE_02959 1.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OLHBHBLE_02960 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OLHBHBLE_02961 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OLHBHBLE_02962 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
OLHBHBLE_02963 0.0 ilvB 2.2.1.6 E Acetolactate synthase
OLHBHBLE_02965 7.6e-82 ysnE K acetyltransferase
OLHBHBLE_02966 9.1e-134 ysnF S protein conserved in bacteria
OLHBHBLE_02968 1.4e-92 ysnB S Phosphoesterase
OLHBHBLE_02969 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OLHBHBLE_02970 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OLHBHBLE_02971 2.9e-196 gerM S COG5401 Spore germination protein
OLHBHBLE_02972 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OLHBHBLE_02973 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_02974 3.3e-30 gerE K Transcriptional regulator
OLHBHBLE_02975 9.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
OLHBHBLE_02976 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OLHBHBLE_02977 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OLHBHBLE_02978 2.4e-107 sdhC C succinate dehydrogenase
OLHBHBLE_02979 1.2e-79 yslB S Protein of unknown function (DUF2507)
OLHBHBLE_02980 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OLHBHBLE_02981 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OLHBHBLE_02982 2e-52 trxA O Belongs to the thioredoxin family
OLHBHBLE_02983 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OLHBHBLE_02985 4.2e-178 etfA C Electron transfer flavoprotein
OLHBHBLE_02986 1.2e-135 etfB C Electron transfer flavoprotein
OLHBHBLE_02987 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OLHBHBLE_02988 2.7e-100 fadR K Transcriptional regulator
OLHBHBLE_02989 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OLHBHBLE_02990 7.3e-68 yshE S membrane
OLHBHBLE_02991 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OLHBHBLE_02992 0.0 polX L COG1796 DNA polymerase IV (family X)
OLHBHBLE_02993 3.9e-85 cvpA S membrane protein, required for colicin V production
OLHBHBLE_02994 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OLHBHBLE_02995 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OLHBHBLE_02996 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OLHBHBLE_02997 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OLHBHBLE_02998 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OLHBHBLE_02999 2.6e-32 sspI S Belongs to the SspI family
OLHBHBLE_03000 3.7e-207 ysfB KT regulator
OLHBHBLE_03001 1.6e-258 glcD 1.1.3.15 C Glycolate oxidase subunit
OLHBHBLE_03002 3.5e-252 glcF C Glycolate oxidase
OLHBHBLE_03003 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
OLHBHBLE_03005 0.0 cstA T Carbon starvation protein
OLHBHBLE_03006 1.1e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OLHBHBLE_03007 3.8e-143 araQ G transport system permease
OLHBHBLE_03008 4.2e-167 araP G carbohydrate transport
OLHBHBLE_03009 2.9e-251 araN G carbohydrate transport
OLHBHBLE_03010 3.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OLHBHBLE_03011 8.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
OLHBHBLE_03012 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OLHBHBLE_03013 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
OLHBHBLE_03014 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OLHBHBLE_03015 1.2e-99 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OLHBHBLE_03016 7.9e-57 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OLHBHBLE_03017 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
OLHBHBLE_03018 9.2e-68 ysdB S Sigma-w pathway protein YsdB
OLHBHBLE_03019 1.7e-44 ysdA S Membrane
OLHBHBLE_03020 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OLHBHBLE_03021 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OLHBHBLE_03022 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OLHBHBLE_03024 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OLHBHBLE_03025 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OLHBHBLE_03026 7.8e-129 lytT T COG3279 Response regulator of the LytR AlgR family
OLHBHBLE_03027 0.0 lytS 2.7.13.3 T Histidine kinase
OLHBHBLE_03028 1.1e-147 ysaA S HAD-hyrolase-like
OLHBHBLE_03029 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OLHBHBLE_03031 1.1e-155 ytxC S YtxC-like family
OLHBHBLE_03032 4.9e-111 ytxB S SNARE associated Golgi protein
OLHBHBLE_03033 6.6e-173 dnaI L Primosomal protein DnaI
OLHBHBLE_03034 2.9e-265 dnaB L Membrane attachment protein
OLHBHBLE_03035 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OLHBHBLE_03036 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OLHBHBLE_03037 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OLHBHBLE_03038 8.4e-66 ytcD K Transcriptional regulator
OLHBHBLE_03039 4.9e-205 ytbD EGP Major facilitator Superfamily
OLHBHBLE_03040 8.9e-161 ytbE S reductase
OLHBHBLE_03041 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OLHBHBLE_03042 1.1e-107 ytaF P Probably functions as a manganese efflux pump
OLHBHBLE_03043 2.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OLHBHBLE_03044 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OLHBHBLE_03045 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
OLHBHBLE_03046 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_03047 1.2e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OLHBHBLE_03048 4.1e-242 icd 1.1.1.42 C isocitrate
OLHBHBLE_03049 1.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
OLHBHBLE_03050 5.2e-70 yeaL S membrane
OLHBHBLE_03051 2.6e-192 ytvI S sporulation integral membrane protein YtvI
OLHBHBLE_03052 4.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
OLHBHBLE_03053 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OLHBHBLE_03054 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OLHBHBLE_03055 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OLHBHBLE_03056 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OLHBHBLE_03057 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
OLHBHBLE_03058 0.0 dnaE 2.7.7.7 L DNA polymerase
OLHBHBLE_03059 3.2e-56 ytrH S Sporulation protein YtrH
OLHBHBLE_03060 8.2e-69 ytrI
OLHBHBLE_03061 9.2e-29
OLHBHBLE_03062 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OLHBHBLE_03063 2.4e-47 ytpI S YtpI-like protein
OLHBHBLE_03064 8e-241 ytoI K transcriptional regulator containing CBS domains
OLHBHBLE_03065 1.2e-158 ytnM S membrane transporter protein
OLHBHBLE_03066 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
OLHBHBLE_03067 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
OLHBHBLE_03068 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLHBHBLE_03069 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
OLHBHBLE_03070 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLHBHBLE_03071 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OLHBHBLE_03072 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
OLHBHBLE_03073 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
OLHBHBLE_03074 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
OLHBHBLE_03075 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
OLHBHBLE_03076 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
OLHBHBLE_03077 2.9e-173 ytlI K LysR substrate binding domain
OLHBHBLE_03078 1.7e-130 ytkL S Belongs to the UPF0173 family
OLHBHBLE_03079 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_03081 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
OLHBHBLE_03082 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OLHBHBLE_03083 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OLHBHBLE_03084 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OLHBHBLE_03085 5.4e-165 ytxK 2.1.1.72 L DNA methylase
OLHBHBLE_03086 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OLHBHBLE_03087 8.7e-70 ytfJ S Sporulation protein YtfJ
OLHBHBLE_03088 5.6e-116 ytfI S Protein of unknown function (DUF2953)
OLHBHBLE_03089 2.5e-86 yteJ S RDD family
OLHBHBLE_03090 2.4e-181 sppA OU signal peptide peptidase SppA
OLHBHBLE_03091 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OLHBHBLE_03092 0.0 ytcJ S amidohydrolase
OLHBHBLE_03093 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OLHBHBLE_03094 2e-29 sspB S spore protein
OLHBHBLE_03095 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OLHBHBLE_03096 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
OLHBHBLE_03097 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
OLHBHBLE_03098 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OLHBHBLE_03099 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OLHBHBLE_03100 3.4e-109 yttP K Transcriptional regulator
OLHBHBLE_03101 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
OLHBHBLE_03102 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OLHBHBLE_03103 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OLHBHBLE_03105 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OLHBHBLE_03106 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OLHBHBLE_03107 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OLHBHBLE_03108 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
OLHBHBLE_03109 1.9e-225 acuC BQ histone deacetylase
OLHBHBLE_03110 1.4e-125 motS N Flagellar motor protein
OLHBHBLE_03111 7.1e-147 motA N flagellar motor
OLHBHBLE_03112 1.7e-182 ccpA K catabolite control protein A
OLHBHBLE_03113 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OLHBHBLE_03114 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
OLHBHBLE_03115 6.6e-17 ytxH S COG4980 Gas vesicle protein
OLHBHBLE_03116 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OLHBHBLE_03117 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OLHBHBLE_03118 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OLHBHBLE_03119 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OLHBHBLE_03120 9.8e-149 ytpQ S Belongs to the UPF0354 family
OLHBHBLE_03121 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OLHBHBLE_03122 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
OLHBHBLE_03123 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OLHBHBLE_03124 9.8e-52 ytzB S small secreted protein
OLHBHBLE_03125 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
OLHBHBLE_03126 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OLHBHBLE_03127 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OLHBHBLE_03128 2e-45 ytzH S YtzH-like protein
OLHBHBLE_03129 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
OLHBHBLE_03130 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
OLHBHBLE_03131 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OLHBHBLE_03132 1.3e-165 ytlQ
OLHBHBLE_03133 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OLHBHBLE_03134 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OLHBHBLE_03135 7.1e-272 pepV 3.5.1.18 E Dipeptidase
OLHBHBLE_03136 7.2e-226 pbuO S permease
OLHBHBLE_03137 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
OLHBHBLE_03138 4.3e-132 ythP V ABC transporter
OLHBHBLE_03139 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OLHBHBLE_03140 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OLHBHBLE_03141 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLHBHBLE_03142 8.2e-232 ytfP S HI0933-like protein
OLHBHBLE_03143 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
OLHBHBLE_03144 3.1e-26 yteV S Sporulation protein Cse60
OLHBHBLE_03145 4.8e-117 yteU S Integral membrane protein
OLHBHBLE_03146 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
OLHBHBLE_03147 4.6e-73 yteS G transport
OLHBHBLE_03148 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
OLHBHBLE_03149 2.2e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
OLHBHBLE_03150 1.4e-163 ytdP K Transcriptional regulator
OLHBHBLE_03151 3.7e-221 ytdP K Transcriptional regulator
OLHBHBLE_03152 2.4e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
OLHBHBLE_03153 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
OLHBHBLE_03154 8.1e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
OLHBHBLE_03155 3.5e-219 bioI 1.14.14.46 C Cytochrome P450
OLHBHBLE_03156 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OLHBHBLE_03157 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OLHBHBLE_03158 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OLHBHBLE_03159 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OLHBHBLE_03160 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OLHBHBLE_03161 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
OLHBHBLE_03162 2.3e-190 msmR K Transcriptional regulator
OLHBHBLE_03163 2.1e-246 msmE G Bacterial extracellular solute-binding protein
OLHBHBLE_03164 1.5e-169 amyD P ABC transporter
OLHBHBLE_03165 1.5e-144 amyC P ABC transporter (permease)
OLHBHBLE_03166 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OLHBHBLE_03167 2.1e-51 ytwF P Sulfurtransferase
OLHBHBLE_03168 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OLHBHBLE_03169 7.7e-55 ytvB S Protein of unknown function (DUF4257)
OLHBHBLE_03170 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OLHBHBLE_03171 2.1e-211 yttB EGP Major facilitator Superfamily
OLHBHBLE_03172 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
OLHBHBLE_03173 0.0 bceB V ABC transporter (permease)
OLHBHBLE_03174 1.1e-138 bceA V ABC transporter, ATP-binding protein
OLHBHBLE_03175 5.6e-186 T PhoQ Sensor
OLHBHBLE_03176 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_03177 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
OLHBHBLE_03178 3.1e-127 ytrE V ABC transporter, ATP-binding protein
OLHBHBLE_03179 5.9e-148
OLHBHBLE_03180 6.1e-169 P ABC-2 family transporter protein
OLHBHBLE_03181 1.1e-161 ytrB P abc transporter atp-binding protein
OLHBHBLE_03182 5.1e-66 ytrA K GntR family transcriptional regulator
OLHBHBLE_03184 6.7e-41 ytzC S Protein of unknown function (DUF2524)
OLHBHBLE_03185 2.1e-190 yhcC S Fe-S oxidoreductase
OLHBHBLE_03186 3.3e-106 ytqB J Putative rRNA methylase
OLHBHBLE_03187 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OLHBHBLE_03188 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
OLHBHBLE_03189 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OLHBHBLE_03190 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
OLHBHBLE_03191 0.0 asnB 6.3.5.4 E Asparagine synthase
OLHBHBLE_03192 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OLHBHBLE_03193 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OLHBHBLE_03194 1.2e-38 ytmB S Protein of unknown function (DUF2584)
OLHBHBLE_03195 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OLHBHBLE_03196 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OLHBHBLE_03197 1.4e-144 ytlC P ABC transporter
OLHBHBLE_03198 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OLHBHBLE_03199 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OLHBHBLE_03200 5.4e-63 ytkC S Bacteriophage holin family
OLHBHBLE_03201 2.1e-76 dps P Belongs to the Dps family
OLHBHBLE_03203 3.6e-73 ytkA S YtkA-like
OLHBHBLE_03204 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OLHBHBLE_03205 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OLHBHBLE_03206 3.6e-41 rpmE2 J Ribosomal protein L31
OLHBHBLE_03207 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
OLHBHBLE_03208 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OLHBHBLE_03209 1.1e-24 S Domain of Unknown Function (DUF1540)
OLHBHBLE_03210 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
OLHBHBLE_03211 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OLHBHBLE_03212 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OLHBHBLE_03213 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
OLHBHBLE_03214 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OLHBHBLE_03215 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OLHBHBLE_03216 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OLHBHBLE_03217 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OLHBHBLE_03218 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OLHBHBLE_03219 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
OLHBHBLE_03220 2.6e-132 dksA T COG1734 DnaK suppressor protein
OLHBHBLE_03221 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
OLHBHBLE_03222 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OLHBHBLE_03223 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
OLHBHBLE_03224 3.6e-235 ytcC M Glycosyltransferase Family 4
OLHBHBLE_03226 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
OLHBHBLE_03227 1.8e-217 cotSA M Glycosyl transferases group 1
OLHBHBLE_03228 1.8e-206 cotI S Spore coat protein
OLHBHBLE_03229 9.9e-77 tspO T membrane
OLHBHBLE_03230 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
OLHBHBLE_03231 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
OLHBHBLE_03232 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
OLHBHBLE_03233 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OLHBHBLE_03234 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OLHBHBLE_03243 7.8e-08
OLHBHBLE_03244 1.3e-09
OLHBHBLE_03251 2e-08
OLHBHBLE_03256 3.4e-39 S COG NOG14552 non supervised orthologous group
OLHBHBLE_03257 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
OLHBHBLE_03258 3.4e-94 M1-753 M FR47-like protein
OLHBHBLE_03259 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
OLHBHBLE_03260 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OLHBHBLE_03261 3.9e-84 yuaE S DinB superfamily
OLHBHBLE_03262 7.9e-108 yuaD
OLHBHBLE_03263 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
OLHBHBLE_03264 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OLHBHBLE_03265 1.1e-95 yuaC K Belongs to the GbsR family
OLHBHBLE_03266 2.2e-91 yuaB
OLHBHBLE_03267 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
OLHBHBLE_03268 5.4e-237 ktrB P Potassium
OLHBHBLE_03269 1e-38 yiaA S yiaA/B two helix domain
OLHBHBLE_03270 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OLHBHBLE_03271 6.2e-277 yubD P Major Facilitator Superfamily
OLHBHBLE_03272 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
OLHBHBLE_03274 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OLHBHBLE_03275 6.3e-197 yubA S transporter activity
OLHBHBLE_03276 3.3e-183 ygjR S Oxidoreductase
OLHBHBLE_03277 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
OLHBHBLE_03278 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
OLHBHBLE_03279 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
OLHBHBLE_03280 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
OLHBHBLE_03281 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
OLHBHBLE_03282 5.1e-239 mcpA NT chemotaxis protein
OLHBHBLE_03283 2.2e-295 mcpA NT chemotaxis protein
OLHBHBLE_03284 1.5e-222 mcpA NT chemotaxis protein
OLHBHBLE_03285 3.2e-225 mcpA NT chemotaxis protein
OLHBHBLE_03286 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
OLHBHBLE_03287 1e-35
OLHBHBLE_03288 2.1e-72 yugU S Uncharacterised protein family UPF0047
OLHBHBLE_03289 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OLHBHBLE_03290 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
OLHBHBLE_03291 1.4e-116 yugP S Zn-dependent protease
OLHBHBLE_03292 4.6e-39
OLHBHBLE_03293 1.1e-53 mstX S Membrane-integrating protein Mistic
OLHBHBLE_03294 1.7e-182 yugO P COG1226 Kef-type K transport systems
OLHBHBLE_03295 1.3e-72 yugN S YugN-like family
OLHBHBLE_03297 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
OLHBHBLE_03298 2.8e-229 yugK C Dehydrogenase
OLHBHBLE_03299 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OLHBHBLE_03300 1.1e-34 yuzA S Domain of unknown function (DUF378)
OLHBHBLE_03301 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OLHBHBLE_03302 4.3e-200 yugH 2.6.1.1 E Aminotransferase
OLHBHBLE_03303 1.6e-85 alaR K Transcriptional regulator
OLHBHBLE_03304 1e-156 yugF I Hydrolase
OLHBHBLE_03305 9.8e-42 yugE S Domain of unknown function (DUF1871)
OLHBHBLE_03306 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OLHBHBLE_03307 7.8e-233 T PhoQ Sensor
OLHBHBLE_03308 2e-70 kapB G Kinase associated protein B
OLHBHBLE_03309 1.9e-115 kapD L the KinA pathway to sporulation
OLHBHBLE_03311 3.5e-186 yuxJ EGP Major facilitator Superfamily
OLHBHBLE_03312 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
OLHBHBLE_03313 6.3e-75 yuxK S protein conserved in bacteria
OLHBHBLE_03314 6.3e-78 yufK S Family of unknown function (DUF5366)
OLHBHBLE_03315 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OLHBHBLE_03316 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
OLHBHBLE_03317 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OLHBHBLE_03318 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OLHBHBLE_03319 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
OLHBHBLE_03320 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
OLHBHBLE_03321 1.3e-233 maeN C COG3493 Na citrate symporter
OLHBHBLE_03322 1.9e-14
OLHBHBLE_03323 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OLHBHBLE_03324 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLHBHBLE_03325 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLHBHBLE_03326 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLHBHBLE_03327 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLHBHBLE_03328 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OLHBHBLE_03329 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
OLHBHBLE_03330 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
OLHBHBLE_03331 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLHBHBLE_03332 0.0 comP 2.7.13.3 T Histidine kinase
OLHBHBLE_03334 2.5e-162 comQ H Polyprenyl synthetase
OLHBHBLE_03336 1.1e-22 yuzC
OLHBHBLE_03337 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
OLHBHBLE_03338 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OLHBHBLE_03339 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
OLHBHBLE_03340 1.6e-67 yueI S Protein of unknown function (DUF1694)
OLHBHBLE_03341 7.4e-39 yueH S YueH-like protein
OLHBHBLE_03342 2.1e-32 yueG S Spore germination protein gerPA/gerPF
OLHBHBLE_03343 1.9e-190 yueF S transporter activity
OLHBHBLE_03344 6.1e-72 S Protein of unknown function (DUF2283)
OLHBHBLE_03345 2.9e-24 S Protein of unknown function (DUF2642)
OLHBHBLE_03346 4.8e-96 yueE S phosphohydrolase
OLHBHBLE_03347 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_03348 6.6e-65 yueC S Family of unknown function (DUF5383)
OLHBHBLE_03349 0.0 esaA S type VII secretion protein EsaA
OLHBHBLE_03350 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OLHBHBLE_03351 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
OLHBHBLE_03352 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
OLHBHBLE_03353 2.8e-45 esxA S Belongs to the WXG100 family
OLHBHBLE_03354 6.5e-229 yukF QT Transcriptional regulator
OLHBHBLE_03355 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OLHBHBLE_03356 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
OLHBHBLE_03357 3.8e-36 mbtH S MbtH-like protein
OLHBHBLE_03358 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_03359 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
OLHBHBLE_03360 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
OLHBHBLE_03361 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
OLHBHBLE_03362 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_03363 1.3e-167 besA S Putative esterase
OLHBHBLE_03364 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
OLHBHBLE_03365 1.1e-93 bioY S Biotin biosynthesis protein
OLHBHBLE_03366 3.9e-211 yuiF S antiporter
OLHBHBLE_03367 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OLHBHBLE_03368 1.2e-77 yuiD S protein conserved in bacteria
OLHBHBLE_03369 9.5e-118 yuiC S protein conserved in bacteria
OLHBHBLE_03370 8.4e-27 yuiB S Putative membrane protein
OLHBHBLE_03371 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
OLHBHBLE_03372 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
OLHBHBLE_03374 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OLHBHBLE_03375 9e-118 paiB K Putative FMN-binding domain
OLHBHBLE_03376 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLHBHBLE_03377 3.7e-63 erpA S Belongs to the HesB IscA family
OLHBHBLE_03378 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OLHBHBLE_03379 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OLHBHBLE_03380 3.2e-39 yuzB S Belongs to the UPF0349 family
OLHBHBLE_03381 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
OLHBHBLE_03382 3.5e-57 yuzD S protein conserved in bacteria
OLHBHBLE_03383 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
OLHBHBLE_03384 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
OLHBHBLE_03385 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OLHBHBLE_03386 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OLHBHBLE_03387 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
OLHBHBLE_03388 2e-199 yutH S Spore coat protein
OLHBHBLE_03389 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OLHBHBLE_03390 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OLHBHBLE_03391 3.9e-75 yutE S Protein of unknown function DUF86
OLHBHBLE_03392 9.7e-48 yutD S protein conserved in bacteria
OLHBHBLE_03393 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OLHBHBLE_03394 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OLHBHBLE_03395 4.5e-196 lytH M Peptidase, M23
OLHBHBLE_03396 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
OLHBHBLE_03397 4.8e-48 yunC S Domain of unknown function (DUF1805)
OLHBHBLE_03398 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OLHBHBLE_03399 2e-141 yunE S membrane transporter protein
OLHBHBLE_03400 4.3e-171 yunF S Protein of unknown function DUF72
OLHBHBLE_03401 3e-62 yunG
OLHBHBLE_03402 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OLHBHBLE_03403 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
OLHBHBLE_03404 2.1e-236 pbuX F Permease family
OLHBHBLE_03405 1.3e-224 pbuX F xanthine
OLHBHBLE_03406 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
OLHBHBLE_03407 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
OLHBHBLE_03408 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OLHBHBLE_03409 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OLHBHBLE_03410 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OLHBHBLE_03411 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
OLHBHBLE_03412 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OLHBHBLE_03414 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OLHBHBLE_03415 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OLHBHBLE_03416 2.4e-169 bsn L Ribonuclease
OLHBHBLE_03417 1.2e-205 msmX P Belongs to the ABC transporter superfamily
OLHBHBLE_03418 1.1e-135 yurK K UTRA
OLHBHBLE_03419 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
OLHBHBLE_03420 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
OLHBHBLE_03421 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
OLHBHBLE_03422 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
OLHBHBLE_03423 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OLHBHBLE_03424 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
OLHBHBLE_03425 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OLHBHBLE_03427 1e-41
OLHBHBLE_03428 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLHBHBLE_03429 3.5e-271 sufB O FeS cluster assembly
OLHBHBLE_03430 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OLHBHBLE_03431 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OLHBHBLE_03432 1.4e-245 sufD O assembly protein SufD
OLHBHBLE_03433 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OLHBHBLE_03434 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OLHBHBLE_03435 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
OLHBHBLE_03436 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
OLHBHBLE_03437 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OLHBHBLE_03438 2.4e-56 yusD S SCP-2 sterol transfer family
OLHBHBLE_03439 5.6e-55 traF CO Thioredoxin
OLHBHBLE_03440 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
OLHBHBLE_03441 1.1e-39 yusG S Protein of unknown function (DUF2553)
OLHBHBLE_03442 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OLHBHBLE_03443 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
OLHBHBLE_03444 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OLHBHBLE_03445 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
OLHBHBLE_03446 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OLHBHBLE_03447 4.7e-09 S YuzL-like protein
OLHBHBLE_03448 2.2e-165 fadM E Proline dehydrogenase
OLHBHBLE_03449 5.1e-40
OLHBHBLE_03450 3.2e-53 yusN M Coat F domain
OLHBHBLE_03451 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
OLHBHBLE_03452 3.8e-293 yusP P Major facilitator superfamily
OLHBHBLE_03453 8.4e-66 yusQ S Tautomerase enzyme
OLHBHBLE_03454 1e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_03455 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_03456 2.7e-160 yusT K LysR substrate binding domain
OLHBHBLE_03457 3.8e-47 yusU S Protein of unknown function (DUF2573)
OLHBHBLE_03458 1e-153 yusV 3.6.3.34 HP ABC transporter
OLHBHBLE_03459 5.6e-66 S YusW-like protein
OLHBHBLE_03460 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
OLHBHBLE_03461 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
OLHBHBLE_03462 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_03463 1.2e-79 dps P Ferritin-like domain
OLHBHBLE_03464 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OLHBHBLE_03465 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_03466 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
OLHBHBLE_03467 4.3e-158 yuxN K Transcriptional regulator
OLHBHBLE_03468 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OLHBHBLE_03469 2.3e-24 S Protein of unknown function (DUF3970)
OLHBHBLE_03470 2.2e-247 gerAA EG Spore germination protein
OLHBHBLE_03471 9.1e-198 gerAB E Spore germination protein
OLHBHBLE_03472 3.7e-91 gerAC S Spore germination B3/ GerAC like, C-terminal
OLHBHBLE_03473 1.1e-50 gerAC S Spore germination B3/ GerAC like, C-terminal
OLHBHBLE_03474 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLHBHBLE_03475 5.5e-187 vraS 2.7.13.3 T Histidine kinase
OLHBHBLE_03476 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
OLHBHBLE_03477 9.3e-129 liaG S Putative adhesin
OLHBHBLE_03478 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OLHBHBLE_03479 5.6e-62 liaI S membrane
OLHBHBLE_03480 4.8e-227 yvqJ EGP Major facilitator Superfamily
OLHBHBLE_03481 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
OLHBHBLE_03482 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OLHBHBLE_03483 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_03484 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
OLHBHBLE_03485 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_03486 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
OLHBHBLE_03487 0.0 T PhoQ Sensor
OLHBHBLE_03488 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_03489 3.6e-22
OLHBHBLE_03490 1.8e-96 yvrI K RNA polymerase
OLHBHBLE_03491 2.4e-19 S YvrJ protein family
OLHBHBLE_03492 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
OLHBHBLE_03493 1.3e-64 yvrL S Regulatory protein YrvL
OLHBHBLE_03494 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
OLHBHBLE_03495 7.1e-124 macB V ABC transporter, ATP-binding protein
OLHBHBLE_03496 4.8e-176 M Efflux transporter rnd family, mfp subunit
OLHBHBLE_03497 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
OLHBHBLE_03498 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_03499 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OLHBHBLE_03500 2.1e-179 fhuD P ABC transporter
OLHBHBLE_03502 2.6e-237 yvsH E Arginine ornithine antiporter
OLHBHBLE_03503 6.5e-16 S Small spore protein J (Spore_SspJ)
OLHBHBLE_03504 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
OLHBHBLE_03505 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OLHBHBLE_03506 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
OLHBHBLE_03507 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
OLHBHBLE_03508 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
OLHBHBLE_03509 9.1e-158 yvgN S reductase
OLHBHBLE_03510 5.4e-86 yvgO
OLHBHBLE_03511 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OLHBHBLE_03512 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OLHBHBLE_03513 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OLHBHBLE_03514 0.0 helD 3.6.4.12 L DNA helicase
OLHBHBLE_03515 4.1e-107 yvgT S membrane
OLHBHBLE_03516 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
OLHBHBLE_03517 1.6e-104 bdbD O Thioredoxin
OLHBHBLE_03518 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OLHBHBLE_03519 0.0 copA 3.6.3.54 P P-type ATPase
OLHBHBLE_03520 1.5e-29 copZ P Copper resistance protein CopZ
OLHBHBLE_03521 2.2e-48 csoR S transcriptional
OLHBHBLE_03522 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
OLHBHBLE_03523 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OLHBHBLE_03524 0.0 yvaC S Fusaric acid resistance protein-like
OLHBHBLE_03525 5.7e-73 yvaD S Family of unknown function (DUF5360)
OLHBHBLE_03526 2.8e-55 yvaE P Small Multidrug Resistance protein
OLHBHBLE_03527 4.1e-101 K Bacterial regulatory proteins, tetR family
OLHBHBLE_03528 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_03530 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OLHBHBLE_03531 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OLHBHBLE_03532 5.6e-143 est 3.1.1.1 S Carboxylesterase
OLHBHBLE_03533 2.4e-23 secG U Preprotein translocase subunit SecG
OLHBHBLE_03534 3.7e-153 yvaM S Serine aminopeptidase, S33
OLHBHBLE_03535 7.5e-36 yvzC K Transcriptional
OLHBHBLE_03536 4e-69 K transcriptional
OLHBHBLE_03537 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
OLHBHBLE_03538 2.2e-54 yodB K transcriptional
OLHBHBLE_03539 4.2e-226 NT chemotaxis protein
OLHBHBLE_03540 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OLHBHBLE_03541 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OLHBHBLE_03542 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OLHBHBLE_03543 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OLHBHBLE_03544 8.7e-61 yvbF K Belongs to the GbsR family
OLHBHBLE_03545 7.9e-13 S Sporulation delaying protein SdpA
OLHBHBLE_03546 7.6e-172
OLHBHBLE_03547 4.4e-08
OLHBHBLE_03548 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
OLHBHBLE_03549 4.5e-45 sdpR K transcriptional
OLHBHBLE_03550 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OLHBHBLE_03551 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OLHBHBLE_03552 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OLHBHBLE_03553 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OLHBHBLE_03554 1.4e-98 yvbF K Belongs to the GbsR family
OLHBHBLE_03555 6.4e-103 yvbG U UPF0056 membrane protein
OLHBHBLE_03556 8.6e-113 yvbH S YvbH-like oligomerisation region
OLHBHBLE_03557 4.2e-124 exoY M Membrane
OLHBHBLE_03558 0.0 tcaA S response to antibiotic
OLHBHBLE_03559 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
OLHBHBLE_03560 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OLHBHBLE_03561 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OLHBHBLE_03562 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OLHBHBLE_03563 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OLHBHBLE_03564 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OLHBHBLE_03565 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OLHBHBLE_03566 1.6e-252 araE EGP Major facilitator Superfamily
OLHBHBLE_03567 5.5e-203 araR K transcriptional
OLHBHBLE_03568 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLHBHBLE_03569 3.9e-159 yvbU K Transcriptional regulator
OLHBHBLE_03570 8.5e-157 yvbV EG EamA-like transporter family
OLHBHBLE_03571 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
OLHBHBLE_03572 4.3e-197 yvbX S Glycosyl hydrolase
OLHBHBLE_03573 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OLHBHBLE_03574 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OLHBHBLE_03575 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OLHBHBLE_03576 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLHBHBLE_03577 8.9e-201 desK 2.7.13.3 T Histidine kinase
OLHBHBLE_03578 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
OLHBHBLE_03579 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
OLHBHBLE_03580 2.6e-157 rsbQ S Alpha/beta hydrolase family
OLHBHBLE_03581 1.4e-199 rsbU 3.1.3.3 T response regulator
OLHBHBLE_03582 2.6e-252 galA 3.2.1.89 G arabinogalactan
OLHBHBLE_03583 0.0 lacA 3.2.1.23 G beta-galactosidase
OLHBHBLE_03584 3.2e-150 ganQ P transport
OLHBHBLE_03585 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
OLHBHBLE_03586 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
OLHBHBLE_03587 1.8e-184 lacR K Transcriptional regulator
OLHBHBLE_03588 6.6e-111 yvfI K COG2186 Transcriptional regulators
OLHBHBLE_03589 1.4e-309 yvfH C L-lactate permease
OLHBHBLE_03590 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OLHBHBLE_03591 1e-31 yvfG S YvfG protein
OLHBHBLE_03592 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
OLHBHBLE_03593 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OLHBHBLE_03594 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
OLHBHBLE_03595 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OLHBHBLE_03596 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLHBHBLE_03597 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OLHBHBLE_03598 3.6e-207 epsI GM pyruvyl transferase
OLHBHBLE_03599 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
OLHBHBLE_03600 4.8e-207 epsG S EpsG family
OLHBHBLE_03601 5.3e-220 epsF GT4 M Glycosyl transferases group 1
OLHBHBLE_03602 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OLHBHBLE_03603 2e-224 epsD GT4 M Glycosyl transferase 4-like
OLHBHBLE_03604 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OLHBHBLE_03605 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
OLHBHBLE_03606 4e-122 ywqC M biosynthesis protein
OLHBHBLE_03607 5.7e-77 slr K transcriptional
OLHBHBLE_03608 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OLHBHBLE_03610 4.6e-93 padC Q Phenolic acid decarboxylase
OLHBHBLE_03611 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
OLHBHBLE_03612 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OLHBHBLE_03613 9.6e-266 pbpE V Beta-lactamase
OLHBHBLE_03614 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
OLHBHBLE_03615 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
OLHBHBLE_03616 1.8e-295 yveA E amino acid
OLHBHBLE_03617 2.6e-106 yvdT K Transcriptional regulator
OLHBHBLE_03618 6.7e-51 ykkC P Small Multidrug Resistance protein
OLHBHBLE_03619 4.1e-50 sugE P Small Multidrug Resistance protein
OLHBHBLE_03620 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
OLHBHBLE_03621 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
OLHBHBLE_03622 1.5e-183 S Patatin-like phospholipase
OLHBHBLE_03624 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OLHBHBLE_03625 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
OLHBHBLE_03626 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
OLHBHBLE_03627 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
OLHBHBLE_03628 1.2e-158 malA S Protein of unknown function (DUF1189)
OLHBHBLE_03629 7.8e-149 malD P transport
OLHBHBLE_03630 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
OLHBHBLE_03631 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
OLHBHBLE_03632 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
OLHBHBLE_03633 3.6e-174 yvdE K Transcriptional regulator
OLHBHBLE_03634 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
OLHBHBLE_03635 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
OLHBHBLE_03636 4.2e-126 catB 2.3.1.28 V Chloramphenicol acetyltransferase
OLHBHBLE_03637 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
OLHBHBLE_03638 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OLHBHBLE_03639 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OLHBHBLE_03640 0.0 yxdM V ABC transporter (permease)
OLHBHBLE_03641 5.6e-141 yvcR V ABC transporter, ATP-binding protein
OLHBHBLE_03642 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
OLHBHBLE_03643 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_03644 1.8e-33
OLHBHBLE_03645 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
OLHBHBLE_03646 1.6e-36 crh G Phosphocarrier protein Chr
OLHBHBLE_03647 1.4e-170 whiA K May be required for sporulation
OLHBHBLE_03648 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OLHBHBLE_03649 5.7e-166 rapZ S Displays ATPase and GTPase activities
OLHBHBLE_03650 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OLHBHBLE_03651 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OLHBHBLE_03652 1.4e-102 usp CBM50 M protein conserved in bacteria
OLHBHBLE_03653 2.4e-278 S COG0457 FOG TPR repeat
OLHBHBLE_03654 0.0 msbA2 3.6.3.44 V ABC transporter
OLHBHBLE_03656 0.0
OLHBHBLE_03657 4.6e-121
OLHBHBLE_03658 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OLHBHBLE_03659 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OLHBHBLE_03660 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OLHBHBLE_03661 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OLHBHBLE_03662 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OLHBHBLE_03663 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OLHBHBLE_03664 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OLHBHBLE_03665 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OLHBHBLE_03666 4.5e-140 yvpB NU protein conserved in bacteria
OLHBHBLE_03667 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
OLHBHBLE_03668 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OLHBHBLE_03669 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OLHBHBLE_03670 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
OLHBHBLE_03671 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OLHBHBLE_03672 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OLHBHBLE_03673 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OLHBHBLE_03674 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OLHBHBLE_03675 3.6e-134 yvoA K transcriptional
OLHBHBLE_03676 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
OLHBHBLE_03677 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_03678 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
OLHBHBLE_03679 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
OLHBHBLE_03680 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_03681 2.7e-203 yvmA EGP Major facilitator Superfamily
OLHBHBLE_03682 1.2e-50 yvlD S Membrane
OLHBHBLE_03683 2.6e-26 pspB KT PspC domain
OLHBHBLE_03684 3.4e-168 yvlB S Putative adhesin
OLHBHBLE_03685 8e-49 yvlA
OLHBHBLE_03686 6.7e-34 yvkN
OLHBHBLE_03687 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OLHBHBLE_03688 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OLHBHBLE_03689 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OLHBHBLE_03690 1.2e-30 csbA S protein conserved in bacteria
OLHBHBLE_03691 0.0 yvkC 2.7.9.2 GT Phosphotransferase
OLHBHBLE_03692 7e-101 yvkB K Transcriptional regulator
OLHBHBLE_03693 7.9e-228 yvkA EGP Major facilitator Superfamily
OLHBHBLE_03694 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OLHBHBLE_03695 1e-54 swrA S Swarming motility protein
OLHBHBLE_03696 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OLHBHBLE_03697 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OLHBHBLE_03698 1.6e-123 ftsE D cell division ATP-binding protein FtsE
OLHBHBLE_03699 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
OLHBHBLE_03700 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OLHBHBLE_03701 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OLHBHBLE_03702 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OLHBHBLE_03703 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OLHBHBLE_03704 2.8e-66
OLHBHBLE_03705 1.9e-08 fliT S bacterial-type flagellum organization
OLHBHBLE_03706 2.9e-69 fliS N flagellar protein FliS
OLHBHBLE_03707 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OLHBHBLE_03708 6.1e-57 flaG N flagellar protein FlaG
OLHBHBLE_03709 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OLHBHBLE_03710 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OLHBHBLE_03711 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OLHBHBLE_03712 2.6e-50 yviE
OLHBHBLE_03713 1.1e-156 flgL N Belongs to the bacterial flagellin family
OLHBHBLE_03714 1.2e-264 flgK N flagellar hook-associated protein
OLHBHBLE_03715 2.4e-78 flgN NOU FlgN protein
OLHBHBLE_03716 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
OLHBHBLE_03717 7e-74 yvyF S flagellar protein
OLHBHBLE_03718 2.7e-129 comFC S Phosphoribosyl transferase domain
OLHBHBLE_03719 5.7e-46 comFB S Late competence development protein ComFB
OLHBHBLE_03720 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OLHBHBLE_03721 7.3e-155 degV S protein conserved in bacteria
OLHBHBLE_03722 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OLHBHBLE_03723 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OLHBHBLE_03724 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OLHBHBLE_03725 6e-163 yvhJ K Transcriptional regulator
OLHBHBLE_03726 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OLHBHBLE_03727 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
OLHBHBLE_03728 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
OLHBHBLE_03729 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
OLHBHBLE_03730 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
OLHBHBLE_03731 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OLHBHBLE_03732 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
OLHBHBLE_03733 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OLHBHBLE_03734 2.7e-78 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OLHBHBLE_03735 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OLHBHBLE_03736 0.0 lytB 3.5.1.28 D Stage II sporulation protein
OLHBHBLE_03737 6e-38
OLHBHBLE_03738 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OLHBHBLE_03739 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OLHBHBLE_03740 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OLHBHBLE_03741 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
OLHBHBLE_03742 8.1e-257 ggaA M Glycosyltransferase like family 2
OLHBHBLE_03744 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OLHBHBLE_03745 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OLHBHBLE_03746 1.1e-150 tagG GM Transport permease protein
OLHBHBLE_03747 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OLHBHBLE_03748 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
OLHBHBLE_03749 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OLHBHBLE_03750 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OLHBHBLE_03751 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OLHBHBLE_03752 1.2e-260
OLHBHBLE_03753 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OLHBHBLE_03754 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
OLHBHBLE_03755 3.5e-266 gerBA EG Spore germination protein
OLHBHBLE_03756 7.5e-200 gerBB E Spore germination protein
OLHBHBLE_03757 7.6e-216 gerAC S Spore germination protein
OLHBHBLE_03758 1.9e-248 ywtG EGP Major facilitator Superfamily
OLHBHBLE_03759 8.4e-171 ywtF K Transcriptional regulator
OLHBHBLE_03760 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
OLHBHBLE_03761 7.7e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OLHBHBLE_03762 3.6e-21 ywtC
OLHBHBLE_03763 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OLHBHBLE_03764 8.6e-70 pgsC S biosynthesis protein
OLHBHBLE_03765 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
OLHBHBLE_03766 3e-176 rbsR K transcriptional
OLHBHBLE_03767 1.3e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OLHBHBLE_03768 2.6e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OLHBHBLE_03769 5.2e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OLHBHBLE_03770 6e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
OLHBHBLE_03771 4.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OLHBHBLE_03772 7.3e-92 batE T Sh3 type 3 domain protein
OLHBHBLE_03773 8e-48 ywsA S Protein of unknown function (DUF3892)
OLHBHBLE_03774 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
OLHBHBLE_03775 4.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
OLHBHBLE_03776 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OLHBHBLE_03777 2.5e-169 alsR K LysR substrate binding domain
OLHBHBLE_03778 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OLHBHBLE_03779 1.1e-124 ywrJ
OLHBHBLE_03780 2.6e-123 cotB
OLHBHBLE_03781 1.8e-206 cotH M Spore Coat
OLHBHBLE_03782 1.3e-12
OLHBHBLE_03783 6.9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OLHBHBLE_03784 5e-54 S Domain of unknown function (DUF4181)
OLHBHBLE_03785 3.4e-307 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OLHBHBLE_03786 2.1e-82 ywrC K Transcriptional regulator
OLHBHBLE_03787 2.4e-104 ywrB P Chromate transporter
OLHBHBLE_03788 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
OLHBHBLE_03790 2.7e-102 ywqN S NAD(P)H-dependent
OLHBHBLE_03791 2.9e-162 K Transcriptional regulator
OLHBHBLE_03792 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
OLHBHBLE_03793 1.7e-52 S MORN repeat variant
OLHBHBLE_03794 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
OLHBHBLE_03795 1.3e-38 ywqI S Family of unknown function (DUF5344)
OLHBHBLE_03796 3.3e-15 S Domain of unknown function (DUF5082)
OLHBHBLE_03797 3.4e-154 ywqG S Domain of unknown function (DUF1963)
OLHBHBLE_03798 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OLHBHBLE_03799 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OLHBHBLE_03800 3.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OLHBHBLE_03801 2e-116 ywqC M biosynthesis protein
OLHBHBLE_03802 1.2e-17
OLHBHBLE_03803 1e-306 ywqB S SWIM zinc finger
OLHBHBLE_03804 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OLHBHBLE_03805 5.7e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
OLHBHBLE_03806 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
OLHBHBLE_03807 2.2e-57 ssbB L Single-stranded DNA-binding protein
OLHBHBLE_03808 1.2e-29 ywpG
OLHBHBLE_03809 6.9e-66 ywpF S YwpF-like protein
OLHBHBLE_03810 5.2e-50 srtA 3.4.22.70 M Sortase family
OLHBHBLE_03811 2.1e-144 ywpD T Histidine kinase
OLHBHBLE_03812 1.1e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OLHBHBLE_03813 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OLHBHBLE_03814 1.2e-197 S aspartate phosphatase
OLHBHBLE_03815 2.6e-141 flhP N flagellar basal body
OLHBHBLE_03816 3.2e-123 flhO N flagellar basal body
OLHBHBLE_03817 3.5e-180 mbl D Rod shape-determining protein
OLHBHBLE_03818 3e-44 spoIIID K Stage III sporulation protein D
OLHBHBLE_03819 2.1e-70 ywoH K COG1846 Transcriptional regulators
OLHBHBLE_03820 3.9e-210 ywoG EGP Major facilitator Superfamily
OLHBHBLE_03821 9.8e-229 ywoF P Right handed beta helix region
OLHBHBLE_03822 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
OLHBHBLE_03823 2.4e-240 ywoD EGP Major facilitator superfamily
OLHBHBLE_03824 3.4e-103 phzA Q Isochorismatase family
OLHBHBLE_03825 1.7e-76
OLHBHBLE_03826 1.3e-224 amt P Ammonium transporter
OLHBHBLE_03827 1.6e-58 nrgB K Belongs to the P(II) protein family
OLHBHBLE_03828 7.7e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OLHBHBLE_03829 5.6e-71 ywnJ S VanZ like family
OLHBHBLE_03830 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OLHBHBLE_03831 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OLHBHBLE_03832 1.3e-08 ywnC S Family of unknown function (DUF5362)
OLHBHBLE_03833 1.5e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
OLHBHBLE_03834 2.2e-70 ywnF S Family of unknown function (DUF5392)
OLHBHBLE_03835 4.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OLHBHBLE_03836 2.1e-140 mta K transcriptional
OLHBHBLE_03837 2.6e-59 ywnC S Family of unknown function (DUF5362)
OLHBHBLE_03838 9.9e-112 ywnB S NAD(P)H-binding
OLHBHBLE_03839 1.7e-64 ywnA K Transcriptional regulator
OLHBHBLE_03840 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OLHBHBLE_03841 2.2e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OLHBHBLE_03842 1.8e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OLHBHBLE_03844 1.4e-10 csbD K CsbD-like
OLHBHBLE_03845 1.1e-83 ywmF S Peptidase M50
OLHBHBLE_03846 1.3e-103 S response regulator aspartate phosphatase
OLHBHBLE_03847 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OLHBHBLE_03848 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OLHBHBLE_03850 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
OLHBHBLE_03851 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
OLHBHBLE_03852 2e-178 spoIID D Stage II sporulation protein D
OLHBHBLE_03853 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OLHBHBLE_03854 1.6e-134 ywmB S TATA-box binding
OLHBHBLE_03855 1.3e-32 ywzB S membrane
OLHBHBLE_03856 4.3e-88 ywmA
OLHBHBLE_03857 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OLHBHBLE_03858 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OLHBHBLE_03859 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OLHBHBLE_03860 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OLHBHBLE_03861 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OLHBHBLE_03862 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OLHBHBLE_03863 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OLHBHBLE_03864 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
OLHBHBLE_03865 2.5e-62 atpI S ATP synthase
OLHBHBLE_03866 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OLHBHBLE_03867 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OLHBHBLE_03868 7.2e-95 ywlG S Belongs to the UPF0340 family
OLHBHBLE_03869 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OLHBHBLE_03870 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OLHBHBLE_03871 1.7e-91 mntP P Probably functions as a manganese efflux pump
OLHBHBLE_03872 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OLHBHBLE_03873 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
OLHBHBLE_03874 6.1e-112 spoIIR S stage II sporulation protein R
OLHBHBLE_03875 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
OLHBHBLE_03877 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OLHBHBLE_03878 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OLHBHBLE_03879 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLHBHBLE_03880 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OLHBHBLE_03881 8.6e-160 ywkB S Membrane transport protein
OLHBHBLE_03882 0.0 sfcA 1.1.1.38 C malic enzyme
OLHBHBLE_03883 2.4e-104 tdk 2.7.1.21 F thymidine kinase
OLHBHBLE_03884 1.1e-32 rpmE J Binds the 23S rRNA
OLHBHBLE_03885 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OLHBHBLE_03886 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OLHBHBLE_03887 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OLHBHBLE_03888 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OLHBHBLE_03889 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OLHBHBLE_03890 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
OLHBHBLE_03891 2.4e-92 ywjG S Domain of unknown function (DUF2529)
OLHBHBLE_03892 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OLHBHBLE_03893 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OLHBHBLE_03894 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
OLHBHBLE_03895 0.0 fadF C COG0247 Fe-S oxidoreductase
OLHBHBLE_03896 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OLHBHBLE_03897 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OLHBHBLE_03898 2.7e-42 ywjC
OLHBHBLE_03899 4.8e-96 ywjB H RibD C-terminal domain
OLHBHBLE_03900 0.0 ywjA V ABC transporter
OLHBHBLE_03901 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OLHBHBLE_03902 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
OLHBHBLE_03903 2.4e-98 narJ 1.7.5.1 C nitrate reductase
OLHBHBLE_03904 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
OLHBHBLE_03905 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OLHBHBLE_03906 7e-86 arfM T cyclic nucleotide binding
OLHBHBLE_03907 1.7e-139 ywiC S YwiC-like protein
OLHBHBLE_03908 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
OLHBHBLE_03909 1e-213 narK P COG2223 Nitrate nitrite transporter
OLHBHBLE_03910 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OLHBHBLE_03911 2.3e-72 ywiB S protein conserved in bacteria
OLHBHBLE_03912 1e-07 S Bacteriocin subtilosin A
OLHBHBLE_03913 4.9e-270 C Fe-S oxidoreductases
OLHBHBLE_03915 1.3e-131 cbiO V ABC transporter
OLHBHBLE_03916 2e-231 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
OLHBHBLE_03917 1.4e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
OLHBHBLE_03918 5.2e-245 L Peptidase, M16
OLHBHBLE_03920 2.9e-249 ywhL CO amine dehydrogenase activity
OLHBHBLE_03921 2.5e-205 ywhK CO amine dehydrogenase activity
OLHBHBLE_03922 2.3e-79 S aspartate phosphatase
OLHBHBLE_03924 1e-84 ywhH S Aminoacyl-tRNA editing domain
OLHBHBLE_03925 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
OLHBHBLE_03926 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OLHBHBLE_03927 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OLHBHBLE_03928 5.2e-95 ywhD S YwhD family
OLHBHBLE_03929 5.1e-119 ywhC S Peptidase family M50
OLHBHBLE_03930 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OLHBHBLE_03931 3.3e-71 ywhA K Transcriptional regulator
OLHBHBLE_03932 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OLHBHBLE_03934 2.6e-242 mmr U Major Facilitator Superfamily
OLHBHBLE_03935 2.8e-79 yffB K Transcriptional regulator
OLHBHBLE_03936 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
OLHBHBLE_03937 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
OLHBHBLE_03938 3.1e-36 ywzC S Belongs to the UPF0741 family
OLHBHBLE_03939 1.6e-111 rsfA_1
OLHBHBLE_03940 5.2e-159 ywfM EG EamA-like transporter family
OLHBHBLE_03941 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OLHBHBLE_03942 9.2e-164 cysL K Transcriptional regulator
OLHBHBLE_03943 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OLHBHBLE_03944 1.1e-146 ywfI C May function as heme-dependent peroxidase
OLHBHBLE_03945 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
OLHBHBLE_03946 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
OLHBHBLE_03947 2.9e-210 bacE EGP Major facilitator Superfamily
OLHBHBLE_03948 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OLHBHBLE_03949 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_03950 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OLHBHBLE_03951 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OLHBHBLE_03952 4.6e-206 ywfA EGP Major facilitator Superfamily
OLHBHBLE_03953 4e-262 lysP E amino acid
OLHBHBLE_03954 0.0 rocB E arginine degradation protein
OLHBHBLE_03955 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OLHBHBLE_03956 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OLHBHBLE_03957 7.5e-77
OLHBHBLE_03958 7.8e-55 spsL 5.1.3.13 M Spore Coat
OLHBHBLE_03959 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OLHBHBLE_03960 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OLHBHBLE_03961 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OLHBHBLE_03962 1.7e-190 spsG M Spore Coat
OLHBHBLE_03963 9.7e-132 spsF M Spore Coat
OLHBHBLE_03964 3.2e-214 spsE 2.5.1.56 M acid synthase
OLHBHBLE_03965 4e-164 spsD 2.3.1.210 K Spore Coat
OLHBHBLE_03966 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
OLHBHBLE_03967 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
OLHBHBLE_03968 2.8e-145 spsA M Spore Coat
OLHBHBLE_03969 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OLHBHBLE_03970 4.3e-59 ywdK S small membrane protein
OLHBHBLE_03971 1.3e-238 ywdJ F Xanthine uracil
OLHBHBLE_03972 7.7e-49 ywdI S Family of unknown function (DUF5327)
OLHBHBLE_03973 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OLHBHBLE_03974 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OLHBHBLE_03975 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
OLHBHBLE_03977 1.4e-113 ywdD
OLHBHBLE_03978 1.3e-57 pex K Transcriptional regulator PadR-like family
OLHBHBLE_03979 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OLHBHBLE_03980 2e-28 ywdA
OLHBHBLE_03981 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
OLHBHBLE_03982 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLHBHBLE_03983 1e-139 focA P Formate/nitrite transporter
OLHBHBLE_03984 2.4e-150 sacT K transcriptional antiterminator
OLHBHBLE_03986 0.0 vpr O Belongs to the peptidase S8 family
OLHBHBLE_03987 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLHBHBLE_03988 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OLHBHBLE_03989 2.9e-202 rodA D Belongs to the SEDS family
OLHBHBLE_03990 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
OLHBHBLE_03991 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OLHBHBLE_03992 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OLHBHBLE_03993 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OLHBHBLE_03994 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OLHBHBLE_03995 1e-35 ywzA S membrane
OLHBHBLE_03996 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OLHBHBLE_03997 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OLHBHBLE_03998 9.5e-60 gtcA S GtrA-like protein
OLHBHBLE_03999 2.2e-122 ywcC K transcriptional regulator
OLHBHBLE_04001 9.8e-49 ywcB S Protein of unknown function, DUF485
OLHBHBLE_04002 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OLHBHBLE_04003 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OLHBHBLE_04004 2.6e-225 ywbN P Dyp-type peroxidase family protein
OLHBHBLE_04005 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
OLHBHBLE_04006 4.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
OLHBHBLE_04007 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OLHBHBLE_04008 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OLHBHBLE_04009 4.3e-153 ywbI K Transcriptional regulator
OLHBHBLE_04010 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OLHBHBLE_04011 2.3e-111 ywbG M effector of murein hydrolase
OLHBHBLE_04012 7.3e-209 ywbF EGP Major facilitator Superfamily
OLHBHBLE_04013 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
OLHBHBLE_04014 1e-218 ywbD 2.1.1.191 J Methyltransferase
OLHBHBLE_04015 9.9e-67 ywbC 4.4.1.5 E glyoxalase
OLHBHBLE_04016 2e-126 ywbB S Protein of unknown function (DUF2711)
OLHBHBLE_04017 2.5e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OLHBHBLE_04018 1.4e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
OLHBHBLE_04019 5.4e-240 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLHBHBLE_04020 1.2e-152 sacY K transcriptional antiterminator
OLHBHBLE_04021 1.3e-167 gspA M General stress
OLHBHBLE_04022 4.2e-127 ywaF S Integral membrane protein
OLHBHBLE_04023 8.1e-88 ywaE K Transcriptional regulator
OLHBHBLE_04024 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OLHBHBLE_04025 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OLHBHBLE_04026 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
OLHBHBLE_04027 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OLHBHBLE_04029 5e-14 S D-Ala-teichoic acid biosynthesis protein
OLHBHBLE_04030 5.3e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_04031 1.2e-232 dltB M membrane protein involved in D-alanine export
OLHBHBLE_04032 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OLHBHBLE_04033 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OLHBHBLE_04034 8.6e-47 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_04035 7.8e-64 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_04036 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OLHBHBLE_04037 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OLHBHBLE_04038 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OLHBHBLE_04039 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OLHBHBLE_04040 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
OLHBHBLE_04041 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OLHBHBLE_04042 9.3e-19 yxzF
OLHBHBLE_04043 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OLHBHBLE_04044 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OLHBHBLE_04045 2.6e-214 yxlH EGP Major facilitator Superfamily
OLHBHBLE_04046 1.3e-137 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OLHBHBLE_04047 9.7e-166 yxlF V ABC transporter, ATP-binding protein
OLHBHBLE_04048 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
OLHBHBLE_04049 2.2e-28
OLHBHBLE_04050 5.6e-47 yxlC S Family of unknown function (DUF5345)
OLHBHBLE_04051 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
OLHBHBLE_04052 5e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
OLHBHBLE_04053 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OLHBHBLE_04054 0.0 cydD V ATP-binding protein
OLHBHBLE_04055 0.0 cydD V ATP-binding
OLHBHBLE_04056 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OLHBHBLE_04057 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
OLHBHBLE_04058 1.5e-229 cimH C COG3493 Na citrate symporter
OLHBHBLE_04059 0.0 3.4.24.84 O Peptidase family M48
OLHBHBLE_04061 3e-156 yxkH G Polysaccharide deacetylase
OLHBHBLE_04062 5.9e-205 msmK P Belongs to the ABC transporter superfamily
OLHBHBLE_04063 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
OLHBHBLE_04064 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLHBHBLE_04065 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OLHBHBLE_04066 4.1e-73 yxkC S Domain of unknown function (DUF4352)
OLHBHBLE_04067 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OLHBHBLE_04068 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
OLHBHBLE_04069 1.9e-166 yxjO K LysR substrate binding domain
OLHBHBLE_04070 2.4e-78 S Protein of unknown function (DUF1453)
OLHBHBLE_04071 1.5e-193 yxjM T Signal transduction histidine kinase
OLHBHBLE_04072 8.9e-116 K helix_turn_helix, Lux Regulon
OLHBHBLE_04073 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OLHBHBLE_04076 1e-87 yxjI S LURP-one-related
OLHBHBLE_04077 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
OLHBHBLE_04078 3.1e-217 yxjG 2.1.1.14 E Methionine synthase
OLHBHBLE_04079 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OLHBHBLE_04080 1.7e-114 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OLHBHBLE_04081 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OLHBHBLE_04082 2.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
OLHBHBLE_04083 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
OLHBHBLE_04084 2.1e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OLHBHBLE_04085 1.5e-102 T Domain of unknown function (DUF4163)
OLHBHBLE_04086 3e-47 yxiS
OLHBHBLE_04087 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
OLHBHBLE_04088 6.6e-224 citH C Citrate transporter
OLHBHBLE_04089 3.6e-142 exoK GH16 M licheninase activity
OLHBHBLE_04090 8.3e-151 licT K transcriptional antiterminator
OLHBHBLE_04091 6.2e-112
OLHBHBLE_04092 7.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
OLHBHBLE_04093 2.5e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OLHBHBLE_04094 8.6e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
OLHBHBLE_04097 3.5e-43 yxiJ S YxiJ-like protein
OLHBHBLE_04100 3.2e-32
OLHBHBLE_04101 3.5e-93 yxiI S Protein of unknown function (DUF2716)
OLHBHBLE_04102 9.4e-142
OLHBHBLE_04103 8.3e-13 yxiG
OLHBHBLE_04104 5.3e-16 yxiG
OLHBHBLE_04105 1.9e-38 S Protein of unknown function (DUF2750)
OLHBHBLE_04106 3.4e-52 yxxG
OLHBHBLE_04107 4.3e-68 yxiG
OLHBHBLE_04108 4.9e-76
OLHBHBLE_04109 4.7e-94 S Protein of unknown function (DUF4240)
OLHBHBLE_04110 4.5e-141
OLHBHBLE_04112 7e-55
OLHBHBLE_04113 1.6e-80 wapA M COG3209 Rhs family protein
OLHBHBLE_04114 4.1e-14 yxiJ S YxiJ-like protein
OLHBHBLE_04115 0.0 wapA M COG3209 Rhs family protein
OLHBHBLE_04116 1.8e-162 yxxF EG EamA-like transporter family
OLHBHBLE_04117 1.2e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OLHBHBLE_04118 2.1e-121 1.14.11.45 E 2OG-Fe dioxygenase
OLHBHBLE_04119 1.1e-72 yxiE T Belongs to the universal stress protein A family
OLHBHBLE_04120 2.9e-173 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLHBHBLE_04121 6.8e-93 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLHBHBLE_04122 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OLHBHBLE_04123 3.6e-51
OLHBHBLE_04124 2.2e-78 S SMI1 / KNR4 family
OLHBHBLE_04125 0.0 S nuclease activity
OLHBHBLE_04126 3.6e-39 yxiC S Family of unknown function (DUF5344)
OLHBHBLE_04127 2.1e-21 S Domain of unknown function (DUF5082)
OLHBHBLE_04128 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OLHBHBLE_04129 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OLHBHBLE_04130 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
OLHBHBLE_04131 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OLHBHBLE_04132 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
OLHBHBLE_04133 1.3e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OLHBHBLE_04134 6.1e-252 lysP E amino acid
OLHBHBLE_04135 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OLHBHBLE_04136 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OLHBHBLE_04137 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OLHBHBLE_04138 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OLHBHBLE_04139 3e-153 yxxB S Domain of Unknown Function (DUF1206)
OLHBHBLE_04140 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
OLHBHBLE_04141 2e-255 yxeQ S MmgE/PrpD family
OLHBHBLE_04142 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
OLHBHBLE_04143 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
OLHBHBLE_04144 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
OLHBHBLE_04145 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
OLHBHBLE_04146 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OLHBHBLE_04147 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OLHBHBLE_04149 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OLHBHBLE_04150 6.2e-151 yidA S hydrolases of the HAD superfamily
OLHBHBLE_04153 1.3e-20 yxeE
OLHBHBLE_04154 1.9e-16 yxeD
OLHBHBLE_04155 7.2e-68
OLHBHBLE_04156 2.3e-176 fhuD P ABC transporter
OLHBHBLE_04157 1.5e-58 yxeA S Protein of unknown function (DUF1093)
OLHBHBLE_04158 6.9e-306 yxdM V ABC transporter (permease)
OLHBHBLE_04159 3.4e-68 yxdL V ABC transporter, ATP-binding protein
OLHBHBLE_04160 1.3e-51 yxdL V ABC transporter, ATP-binding protein
OLHBHBLE_04161 7.6e-180 T PhoQ Sensor
OLHBHBLE_04162 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_04163 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OLHBHBLE_04164 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OLHBHBLE_04165 2.3e-167 iolH G Xylose isomerase-like TIM barrel
OLHBHBLE_04166 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OLHBHBLE_04167 1.3e-235 iolF EGP Major facilitator Superfamily
OLHBHBLE_04168 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OLHBHBLE_04169 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OLHBHBLE_04170 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OLHBHBLE_04171 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OLHBHBLE_04172 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OLHBHBLE_04173 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
OLHBHBLE_04174 3.7e-176 iolS C Aldo keto reductase
OLHBHBLE_04176 8.3e-48 yxcD S Protein of unknown function (DUF2653)
OLHBHBLE_04177 2.3e-246 csbC EGP Major facilitator Superfamily
OLHBHBLE_04178 0.0 htpG O Molecular chaperone. Has ATPase activity
OLHBHBLE_04180 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
OLHBHBLE_04181 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
OLHBHBLE_04182 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OLHBHBLE_04183 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
OLHBHBLE_04184 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
OLHBHBLE_04185 3.3e-127 yxbB Q Met-10+ like-protein
OLHBHBLE_04186 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
OLHBHBLE_04187 1.1e-86 yxnB
OLHBHBLE_04188 0.0 asnB 6.3.5.4 E Asparagine synthase
OLHBHBLE_04189 7.6e-214 yxaM U MFS_1 like family
OLHBHBLE_04190 6.8e-93 S PQQ-like domain
OLHBHBLE_04191 3.5e-65 S Family of unknown function (DUF5391)
OLHBHBLE_04192 1.1e-75 yxaI S membrane protein domain
OLHBHBLE_04193 1.4e-228 P Protein of unknown function (DUF418)
OLHBHBLE_04194 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
OLHBHBLE_04195 7.1e-101 yxaF K Transcriptional regulator
OLHBHBLE_04196 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OLHBHBLE_04197 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
OLHBHBLE_04198 5.2e-50 S LrgA family
OLHBHBLE_04199 2.6e-118 yxaC M effector of murein hydrolase
OLHBHBLE_04200 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
OLHBHBLE_04201 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OLHBHBLE_04202 7.3e-127 gntR K transcriptional
OLHBHBLE_04203 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
OLHBHBLE_04204 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
OLHBHBLE_04205 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OLHBHBLE_04206 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OLHBHBLE_04207 3.8e-287 ahpF O Alkyl hydroperoxide reductase
OLHBHBLE_04208 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OLHBHBLE_04209 2.5e-19 bglF G phosphotransferase system
OLHBHBLE_04210 1.3e-128 yydK K Transcriptional regulator
OLHBHBLE_04211 7.6e-13
OLHBHBLE_04212 3.3e-119 S ABC-2 family transporter protein
OLHBHBLE_04213 1.8e-110 prrC P ABC transporter
OLHBHBLE_04214 8.4e-134 yydH O Peptidase M50
OLHBHBLE_04215 7.7e-185 S Radical SAM superfamily
OLHBHBLE_04216 8e-12
OLHBHBLE_04217 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
OLHBHBLE_04218 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
OLHBHBLE_04219 3.5e-65
OLHBHBLE_04220 7.3e-280 S Calcineurin-like phosphoesterase
OLHBHBLE_04221 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OLHBHBLE_04222 1.1e-09 S YyzF-like protein
OLHBHBLE_04223 4.2e-71
OLHBHBLE_04224 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OLHBHBLE_04226 2.1e-33 yycQ S Protein of unknown function (DUF2651)
OLHBHBLE_04227 1.6e-221 yycP
OLHBHBLE_04228 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OLHBHBLE_04229 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
OLHBHBLE_04230 5e-188 S aspartate phosphatase
OLHBHBLE_04232 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OLHBHBLE_04233 9.7e-261 rocE E amino acid
OLHBHBLE_04234 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OLHBHBLE_04235 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OLHBHBLE_04236 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OLHBHBLE_04237 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OLHBHBLE_04238 7.3e-155 yycI S protein conserved in bacteria
OLHBHBLE_04239 3.6e-260 yycH S protein conserved in bacteria
OLHBHBLE_04240 0.0 vicK 2.7.13.3 T Histidine kinase
OLHBHBLE_04241 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OLHBHBLE_04246 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OLHBHBLE_04247 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLHBHBLE_04248 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OLHBHBLE_04249 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
OLHBHBLE_04251 1.9e-15 yycC K YycC-like protein
OLHBHBLE_04252 8.4e-221 yeaN P COG2807 Cyanate permease
OLHBHBLE_04253 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OLHBHBLE_04254 2.2e-73 rplI J binds to the 23S rRNA
OLHBHBLE_04255 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OLHBHBLE_04256 2.9e-160 yybS S membrane
OLHBHBLE_04258 3.9e-84 cotF M Spore coat protein
OLHBHBLE_04259 1.4e-68 ydeP3 K Transcriptional regulator
OLHBHBLE_04260 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OLHBHBLE_04261 1.3e-70
OLHBHBLE_04263 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
OLHBHBLE_04264 1e-16
OLHBHBLE_04265 1.3e-78 yybN S Protein of unknown function (DUF2712)
OLHBHBLE_04266 4.1e-125
OLHBHBLE_04267 9e-122
OLHBHBLE_04268 2e-127 S Protein of unknown function (DUF2705)
OLHBHBLE_04269 2.6e-115 V ATPases associated with a variety of cellular activities
OLHBHBLE_04270 6.2e-132
OLHBHBLE_04271 5.9e-67 yybH S SnoaL-like domain
OLHBHBLE_04272 3e-124 yybG S Pentapeptide repeat-containing protein
OLHBHBLE_04273 3.2e-220 ynfM EGP Major facilitator Superfamily
OLHBHBLE_04274 2.1e-165 yybE K Transcriptional regulator
OLHBHBLE_04275 2e-79 yjcF S Acetyltransferase (GNAT) domain
OLHBHBLE_04276 2.7e-77 yybC
OLHBHBLE_04277 3e-127 S Metallo-beta-lactamase superfamily
OLHBHBLE_04278 5.6e-77 yybA 2.3.1.57 K transcriptional
OLHBHBLE_04279 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
OLHBHBLE_04280 1.5e-101 yyaS S Membrane
OLHBHBLE_04281 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
OLHBHBLE_04282 5.4e-67 yyaQ S YjbR
OLHBHBLE_04283 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
OLHBHBLE_04284 1.7e-249 tetL EGP Major facilitator Superfamily
OLHBHBLE_04285 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
OLHBHBLE_04286 5.1e-61 yyaN K MerR HTH family regulatory protein
OLHBHBLE_04287 3.3e-161 yyaM EG EamA-like transporter family
OLHBHBLE_04288 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OLHBHBLE_04289 9.5e-169 yyaK S CAAX protease self-immunity
OLHBHBLE_04290 3.8e-246 EGP Major facilitator superfamily
OLHBHBLE_04291 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
OLHBHBLE_04292 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OLHBHBLE_04293 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
OLHBHBLE_04294 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
OLHBHBLE_04295 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OLHBHBLE_04296 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OLHBHBLE_04297 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
OLHBHBLE_04298 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OLHBHBLE_04299 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OLHBHBLE_04300 2.3e-33 yyzM S protein conserved in bacteria
OLHBHBLE_04301 8.1e-177 yyaD S Membrane
OLHBHBLE_04302 1.6e-111 yyaC S Sporulation protein YyaC
OLHBHBLE_04303 2.1e-149 spo0J K Belongs to the ParB family
OLHBHBLE_04304 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
OLHBHBLE_04305 1.5e-74 S Bacterial PH domain
OLHBHBLE_04306 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OLHBHBLE_04307 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OLHBHBLE_04308 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OLHBHBLE_04309 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OLHBHBLE_04310 6.5e-108 jag S single-stranded nucleic acid binding R3H
OLHBHBLE_04311 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OLHBHBLE_04312 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)