ORF_ID e_value Gene_name EC_number CAZy COGs Description
KNAKPFIF_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KNAKPFIF_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KNAKPFIF_00003 2.4e-33 yaaA S S4 domain
KNAKPFIF_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KNAKPFIF_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
KNAKPFIF_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNAKPFIF_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KNAKPFIF_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00011 2.7e-182 yaaC S YaaC-like Protein
KNAKPFIF_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KNAKPFIF_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KNAKPFIF_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KNAKPFIF_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KNAKPFIF_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KNAKPFIF_00017 1.3e-09
KNAKPFIF_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KNAKPFIF_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KNAKPFIF_00020 9e-213 yaaH M Glycoside Hydrolase Family
KNAKPFIF_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
KNAKPFIF_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KNAKPFIF_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNAKPFIF_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KNAKPFIF_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KNAKPFIF_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
KNAKPFIF_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
KNAKPFIF_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
KNAKPFIF_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KNAKPFIF_00033 4.5e-203 yaaN P Belongs to the TelA family
KNAKPFIF_00034 1.3e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KNAKPFIF_00035 5.3e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KNAKPFIF_00036 2.2e-54 yaaQ S protein conserved in bacteria
KNAKPFIF_00037 1.5e-71 yaaR S protein conserved in bacteria
KNAKPFIF_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
KNAKPFIF_00039 6.1e-146 yaaT S stage 0 sporulation protein
KNAKPFIF_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
KNAKPFIF_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
KNAKPFIF_00042 1.5e-49 yazA L endonuclease containing a URI domain
KNAKPFIF_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KNAKPFIF_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KNAKPFIF_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KNAKPFIF_00046 2e-143 tatD L hydrolase, TatD
KNAKPFIF_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
KNAKPFIF_00048 9.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KNAKPFIF_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KNAKPFIF_00050 1.6e-136 yabG S peptidase
KNAKPFIF_00051 7.8e-39 veg S protein conserved in bacteria
KNAKPFIF_00052 8.3e-27 sspF S DNA topological change
KNAKPFIF_00053 1.6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KNAKPFIF_00054 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KNAKPFIF_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KNAKPFIF_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KNAKPFIF_00057 7.3e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KNAKPFIF_00058 2.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KNAKPFIF_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KNAKPFIF_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KNAKPFIF_00061 2.4e-39 yabK S Peptide ABC transporter permease
KNAKPFIF_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KNAKPFIF_00063 1.5e-92 spoVT K stage V sporulation protein
KNAKPFIF_00064 1.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KNAKPFIF_00065 5.6e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KNAKPFIF_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KNAKPFIF_00067 1.5e-49 yabP S Sporulation protein YabP
KNAKPFIF_00068 2.5e-107 yabQ S spore cortex biosynthesis protein
KNAKPFIF_00069 1.1e-44 divIC D Septum formation initiator
KNAKPFIF_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KNAKPFIF_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KNAKPFIF_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
KNAKPFIF_00075 2.9e-182 KLT serine threonine protein kinase
KNAKPFIF_00076 2.5e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KNAKPFIF_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KNAKPFIF_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KNAKPFIF_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KNAKPFIF_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KNAKPFIF_00081 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KNAKPFIF_00082 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KNAKPFIF_00083 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KNAKPFIF_00084 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KNAKPFIF_00085 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KNAKPFIF_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KNAKPFIF_00087 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KNAKPFIF_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KNAKPFIF_00089 4.1e-30 yazB K transcriptional
KNAKPFIF_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNAKPFIF_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KNAKPFIF_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00097 2e-08
KNAKPFIF_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00103 2.9e-76 ctsR K Belongs to the CtsR family
KNAKPFIF_00104 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KNAKPFIF_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KNAKPFIF_00106 0.0 clpC O Belongs to the ClpA ClpB family
KNAKPFIF_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KNAKPFIF_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KNAKPFIF_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KNAKPFIF_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KNAKPFIF_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KNAKPFIF_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KNAKPFIF_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
KNAKPFIF_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KNAKPFIF_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KNAKPFIF_00116 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNAKPFIF_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
KNAKPFIF_00118 1.5e-115 sigH K Belongs to the sigma-70 factor family
KNAKPFIF_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KNAKPFIF_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KNAKPFIF_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KNAKPFIF_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KNAKPFIF_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KNAKPFIF_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KNAKPFIF_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
KNAKPFIF_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNAKPFIF_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNAKPFIF_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KNAKPFIF_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KNAKPFIF_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KNAKPFIF_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KNAKPFIF_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KNAKPFIF_00133 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KNAKPFIF_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KNAKPFIF_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KNAKPFIF_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
KNAKPFIF_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KNAKPFIF_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KNAKPFIF_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KNAKPFIF_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KNAKPFIF_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KNAKPFIF_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KNAKPFIF_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KNAKPFIF_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KNAKPFIF_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KNAKPFIF_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KNAKPFIF_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KNAKPFIF_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNAKPFIF_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KNAKPFIF_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KNAKPFIF_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KNAKPFIF_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KNAKPFIF_00153 1.9e-23 rpmD J Ribosomal protein L30
KNAKPFIF_00154 1.8e-72 rplO J binds to the 23S rRNA
KNAKPFIF_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KNAKPFIF_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KNAKPFIF_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
KNAKPFIF_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KNAKPFIF_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KNAKPFIF_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KNAKPFIF_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KNAKPFIF_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KNAKPFIF_00163 3.6e-58 rplQ J Ribosomal protein L17
KNAKPFIF_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNAKPFIF_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNAKPFIF_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KNAKPFIF_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KNAKPFIF_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KNAKPFIF_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KNAKPFIF_00170 8.2e-145 ybaJ Q Methyltransferase domain
KNAKPFIF_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
KNAKPFIF_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KNAKPFIF_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KNAKPFIF_00174 1.2e-84 gerD
KNAKPFIF_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KNAKPFIF_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
KNAKPFIF_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00178 3.3e-39 S COG NOG15344 non supervised orthologous group
KNAKPFIF_00181 2e-08
KNAKPFIF_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00186 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00187 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KNAKPFIF_00189 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
KNAKPFIF_00190 2.2e-142 ybbA S Putative esterase
KNAKPFIF_00191 9.6e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_00192 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_00193 4e-165 feuA P Iron-uptake system-binding protein
KNAKPFIF_00194 1.2e-302 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KNAKPFIF_00195 7.8e-238 ybbC 3.2.1.52 S protein conserved in bacteria
KNAKPFIF_00196 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KNAKPFIF_00197 3.2e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KNAKPFIF_00198 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KNAKPFIF_00199 6.9e-148 ybbH K transcriptional
KNAKPFIF_00200 8.8e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KNAKPFIF_00201 1.9e-86 ybbJ J acetyltransferase
KNAKPFIF_00202 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KNAKPFIF_00208 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_00209 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KNAKPFIF_00210 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KNAKPFIF_00211 4.6e-221 ybbR S protein conserved in bacteria
KNAKPFIF_00212 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KNAKPFIF_00213 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KNAKPFIF_00214 2.6e-42 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KNAKPFIF_00215 3.6e-99 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KNAKPFIF_00216 9.8e-120 adaA 3.2.2.21 K Transcriptional regulator
KNAKPFIF_00217 1.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KNAKPFIF_00218 9.4e-270 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KNAKPFIF_00219 0.0 ybcC S Belongs to the UPF0753 family
KNAKPFIF_00220 6.5e-93 can 4.2.1.1 P carbonic anhydrase
KNAKPFIF_00222 8.7e-47
KNAKPFIF_00223 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
KNAKPFIF_00224 1.5e-50 T Transcriptional regulatory protein, C terminal
KNAKPFIF_00225 5.9e-172 T His Kinase A (phospho-acceptor) domain
KNAKPFIF_00227 6.7e-139 KLT Protein tyrosine kinase
KNAKPFIF_00228 8.5e-151 ybdN
KNAKPFIF_00229 1.5e-214 ybdO S Domain of unknown function (DUF4885)
KNAKPFIF_00230 5.8e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KNAKPFIF_00231 1.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
KNAKPFIF_00232 4.9e-30 ybxH S Family of unknown function (DUF5370)
KNAKPFIF_00233 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
KNAKPFIF_00234 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KNAKPFIF_00235 4.9e-41 ybyB
KNAKPFIF_00236 1.8e-290 ybeC E amino acid
KNAKPFIF_00237 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KNAKPFIF_00238 7.3e-258 glpT G -transporter
KNAKPFIF_00239 2.9e-35 S Protein of unknown function (DUF2651)
KNAKPFIF_00240 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
KNAKPFIF_00241 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
KNAKPFIF_00243 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
KNAKPFIF_00244 8.8e-162 ybfH EG EamA-like transporter family
KNAKPFIF_00245 2.3e-145 msmR K AraC-like ligand binding domain
KNAKPFIF_00246 1.6e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KNAKPFIF_00247 1.3e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KNAKPFIF_00249 2e-166 S Alpha/beta hydrolase family
KNAKPFIF_00250 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNAKPFIF_00251 2.7e-85 ybfM S SNARE associated Golgi protein
KNAKPFIF_00252 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KNAKPFIF_00253 4.6e-45 ybfN
KNAKPFIF_00254 3.4e-255 S Erythromycin esterase
KNAKPFIF_00255 6.7e-167 ybfP K Transcriptional regulator
KNAKPFIF_00256 3.9e-192 yceA S Belongs to the UPF0176 family
KNAKPFIF_00257 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KNAKPFIF_00258 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KNAKPFIF_00259 1.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KNAKPFIF_00260 4.9e-128 K UTRA
KNAKPFIF_00262 1.3e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KNAKPFIF_00263 2.8e-260 mmuP E amino acid
KNAKPFIF_00264 4.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KNAKPFIF_00265 1.4e-30 agcS E Sodium alanine symporter
KNAKPFIF_00266 9.4e-212 agcS E Sodium alanine symporter
KNAKPFIF_00267 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
KNAKPFIF_00268 9.4e-229 phoQ 2.7.13.3 T Histidine kinase
KNAKPFIF_00269 5.8e-169 glnL T Regulator
KNAKPFIF_00270 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
KNAKPFIF_00271 1.9e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KNAKPFIF_00272 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
KNAKPFIF_00273 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KNAKPFIF_00274 1.5e-124 ycbG K FCD
KNAKPFIF_00275 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
KNAKPFIF_00276 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
KNAKPFIF_00277 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KNAKPFIF_00278 7.3e-172 eamA1 EG spore germination
KNAKPFIF_00279 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_00280 2.4e-170 T PhoQ Sensor
KNAKPFIF_00281 4.8e-168 ycbN V ABC transporter, ATP-binding protein
KNAKPFIF_00282 2.1e-115 S ABC-2 family transporter protein
KNAKPFIF_00283 8.2e-53 ycbP S Protein of unknown function (DUF2512)
KNAKPFIF_00284 1.3e-78 sleB 3.5.1.28 M Cell wall
KNAKPFIF_00285 6.6e-136 ycbR T vWA found in TerF C terminus
KNAKPFIF_00286 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KNAKPFIF_00287 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KNAKPFIF_00288 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNAKPFIF_00289 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KNAKPFIF_00290 2.3e-209 ycbU E Selenocysteine lyase
KNAKPFIF_00291 5.8e-229 lmrB EGP the major facilitator superfamily
KNAKPFIF_00292 4.8e-102 yxaF K Transcriptional regulator
KNAKPFIF_00293 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KNAKPFIF_00294 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KNAKPFIF_00295 2e-59 S RDD family
KNAKPFIF_00296 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
KNAKPFIF_00297 2e-161 2.7.13.3 T GHKL domain
KNAKPFIF_00298 1.2e-126 lytR_2 T LytTr DNA-binding domain
KNAKPFIF_00299 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
KNAKPFIF_00300 2.4e-201 natB CP ABC-2 family transporter protein
KNAKPFIF_00301 5e-173 yccK C Aldo keto reductase
KNAKPFIF_00302 1.1e-170 ycdA S Domain of unknown function (DUF5105)
KNAKPFIF_00303 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_00304 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_00305 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
KNAKPFIF_00306 5.5e-174 S response regulator aspartate phosphatase
KNAKPFIF_00307 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
KNAKPFIF_00308 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KNAKPFIF_00309 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
KNAKPFIF_00310 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KNAKPFIF_00311 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KNAKPFIF_00312 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNAKPFIF_00313 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KNAKPFIF_00314 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
KNAKPFIF_00315 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
KNAKPFIF_00316 6.3e-137 terC P Protein of unknown function (DUF475)
KNAKPFIF_00317 0.0 yceG S Putative component of 'biosynthetic module'
KNAKPFIF_00318 2e-192 yceH P Belongs to the TelA family
KNAKPFIF_00319 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
KNAKPFIF_00320 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
KNAKPFIF_00321 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
KNAKPFIF_00322 5.1e-229 proV 3.6.3.32 E glycine betaine
KNAKPFIF_00323 1.3e-127 opuAB P glycine betaine
KNAKPFIF_00324 5.3e-164 opuAC E glycine betaine
KNAKPFIF_00325 5.8e-219 amhX S amidohydrolase
KNAKPFIF_00326 2.1e-255 ycgA S Membrane
KNAKPFIF_00327 1.2e-80 ycgB
KNAKPFIF_00328 3.1e-270 amyE 3.2.1.1 GH13 G alpha-amylase
KNAKPFIF_00329 9.2e-98 amyE 3.2.1.1 GH13 G alpha-amylase
KNAKPFIF_00330 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KNAKPFIF_00331 1.5e-66 lctP C L-lactate permease
KNAKPFIF_00332 1e-210 lctP C L-lactate permease
KNAKPFIF_00333 1.4e-149 yqcI S YqcI/YcgG family
KNAKPFIF_00334 2.4e-76 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KNAKPFIF_00335 2.3e-90 ycgI S Domain of unknown function (DUF1989)
KNAKPFIF_00336 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KNAKPFIF_00337 2.5e-109 tmrB S AAA domain
KNAKPFIF_00338 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KNAKPFIF_00339 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
KNAKPFIF_00340 2.2e-179 oxyR3 K LysR substrate binding domain
KNAKPFIF_00341 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KNAKPFIF_00342 2.9e-145 ycgL S Predicted nucleotidyltransferase
KNAKPFIF_00343 5.1e-170 ycgM E Proline dehydrogenase
KNAKPFIF_00344 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KNAKPFIF_00345 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNAKPFIF_00346 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KNAKPFIF_00347 2.6e-147 ycgQ S membrane
KNAKPFIF_00348 1.2e-139 ycgR S permeases
KNAKPFIF_00349 5.7e-163 I alpha/beta hydrolase fold
KNAKPFIF_00350 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KNAKPFIF_00351 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KNAKPFIF_00352 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
KNAKPFIF_00353 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KNAKPFIF_00354 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KNAKPFIF_00355 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KNAKPFIF_00356 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
KNAKPFIF_00357 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
KNAKPFIF_00358 5.5e-109 yciB M ErfK YbiS YcfS YnhG
KNAKPFIF_00359 1.4e-228 yciC S GTPases (G3E family)
KNAKPFIF_00360 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
KNAKPFIF_00361 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KNAKPFIF_00363 3.3e-77 yckC S membrane
KNAKPFIF_00364 3.5e-52 yckD S Protein of unknown function (DUF2680)
KNAKPFIF_00365 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KNAKPFIF_00366 3.4e-70 nin S Competence protein J (ComJ)
KNAKPFIF_00367 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
KNAKPFIF_00368 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
KNAKPFIF_00369 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KNAKPFIF_00370 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KNAKPFIF_00371 1.3e-63 hxlR K transcriptional
KNAKPFIF_00372 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_00373 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_00374 7.2e-115 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_00375 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KNAKPFIF_00376 5.7e-140 srfAD Q thioesterase
KNAKPFIF_00377 4.2e-228 EGP Major Facilitator Superfamily
KNAKPFIF_00378 4.9e-91 S YcxB-like protein
KNAKPFIF_00379 7.4e-164 ycxC EG EamA-like transporter family
KNAKPFIF_00380 4.4e-255 ycxD K GntR family transcriptional regulator
KNAKPFIF_00381 4.4e-75 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KNAKPFIF_00382 4.4e-115 yczE S membrane
KNAKPFIF_00383 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KNAKPFIF_00384 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
KNAKPFIF_00385 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KNAKPFIF_00386 4.9e-162 bsdA K LysR substrate binding domain
KNAKPFIF_00387 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KNAKPFIF_00388 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KNAKPFIF_00389 4e-39 bsdD 4.1.1.61 S response to toxic substance
KNAKPFIF_00390 1.1e-83 yclD
KNAKPFIF_00391 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
KNAKPFIF_00392 1.5e-267 dtpT E amino acid peptide transporter
KNAKPFIF_00393 3.2e-293 yclG M Pectate lyase superfamily protein
KNAKPFIF_00395 7.3e-276 gerKA EG Spore germination protein
KNAKPFIF_00396 1.5e-225 gerKC S spore germination
KNAKPFIF_00397 8.4e-199 gerKB F Spore germination protein
KNAKPFIF_00398 3.9e-122 yclH P ABC transporter
KNAKPFIF_00399 1.7e-204 yclI V ABC transporter (permease) YclI
KNAKPFIF_00400 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_00401 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KNAKPFIF_00402 5.2e-71 S aspartate phosphatase
KNAKPFIF_00405 1.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
KNAKPFIF_00406 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_00407 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_00408 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KNAKPFIF_00409 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KNAKPFIF_00410 1.4e-251 ycnB EGP Major facilitator Superfamily
KNAKPFIF_00411 6.5e-154 ycnC K Transcriptional regulator
KNAKPFIF_00412 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
KNAKPFIF_00413 1.6e-45 ycnE S Monooxygenase
KNAKPFIF_00414 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KNAKPFIF_00415 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNAKPFIF_00416 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KNAKPFIF_00417 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KNAKPFIF_00418 6.1e-149 glcU U Glucose uptake
KNAKPFIF_00419 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_00420 1.3e-100 ycnI S protein conserved in bacteria
KNAKPFIF_00421 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
KNAKPFIF_00422 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KNAKPFIF_00423 7.3e-56
KNAKPFIF_00424 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KNAKPFIF_00425 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KNAKPFIF_00426 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KNAKPFIF_00427 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KNAKPFIF_00428 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KNAKPFIF_00429 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KNAKPFIF_00430 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
KNAKPFIF_00431 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KNAKPFIF_00433 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KNAKPFIF_00434 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
KNAKPFIF_00435 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KNAKPFIF_00436 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
KNAKPFIF_00437 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KNAKPFIF_00438 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KNAKPFIF_00439 1.2e-132 kipR K Transcriptional regulator
KNAKPFIF_00440 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
KNAKPFIF_00442 1.4e-49 yczJ S biosynthesis
KNAKPFIF_00443 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KNAKPFIF_00444 2.8e-176 ydhF S Oxidoreductase
KNAKPFIF_00445 0.0 mtlR K transcriptional regulator, MtlR
KNAKPFIF_00446 1.4e-294 ydaB IQ acyl-CoA ligase
KNAKPFIF_00447 1.1e-99 ydaC Q Methyltransferase domain
KNAKPFIF_00448 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_00449 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KNAKPFIF_00450 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KNAKPFIF_00451 6.8e-77 ydaG 1.4.3.5 S general stress protein
KNAKPFIF_00452 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KNAKPFIF_00453 5.1e-47 ydzA EGP Major facilitator Superfamily
KNAKPFIF_00454 2.5e-74 lrpC K Transcriptional regulator
KNAKPFIF_00455 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNAKPFIF_00456 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KNAKPFIF_00457 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
KNAKPFIF_00458 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KNAKPFIF_00459 4.5e-233 ydaM M Glycosyl transferase family group 2
KNAKPFIF_00460 0.0 ydaN S Bacterial cellulose synthase subunit
KNAKPFIF_00461 0.0 ydaO E amino acid
KNAKPFIF_00462 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KNAKPFIF_00463 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KNAKPFIF_00464 9.4e-40
KNAKPFIF_00465 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
KNAKPFIF_00467 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KNAKPFIF_00468 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KNAKPFIF_00470 8.9e-59 ydbB G Cupin domain
KNAKPFIF_00471 2.8e-63 ydbC S Domain of unknown function (DUF4937
KNAKPFIF_00472 3.2e-155 ydbD P Catalase
KNAKPFIF_00473 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KNAKPFIF_00474 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KNAKPFIF_00475 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
KNAKPFIF_00476 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KNAKPFIF_00477 4.4e-181 ydbI S AI-2E family transporter
KNAKPFIF_00478 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
KNAKPFIF_00479 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KNAKPFIF_00480 2.7e-52 ydbL
KNAKPFIF_00481 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KNAKPFIF_00482 1.1e-18 S Fur-regulated basic protein B
KNAKPFIF_00483 2.2e-07 S Fur-regulated basic protein A
KNAKPFIF_00484 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNAKPFIF_00485 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KNAKPFIF_00486 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KNAKPFIF_00487 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KNAKPFIF_00488 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KNAKPFIF_00489 2.1e-82 ydbS S Bacterial PH domain
KNAKPFIF_00490 2.2e-263 ydbT S Membrane
KNAKPFIF_00491 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KNAKPFIF_00492 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KNAKPFIF_00493 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KNAKPFIF_00494 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNAKPFIF_00495 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KNAKPFIF_00496 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KNAKPFIF_00497 1.3e-143 rsbR T Positive regulator of sigma-B
KNAKPFIF_00498 5.2e-57 rsbS T antagonist
KNAKPFIF_00499 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KNAKPFIF_00500 7.1e-189 rsbU 3.1.3.3 KT phosphatase
KNAKPFIF_00501 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KNAKPFIF_00502 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KNAKPFIF_00503 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNAKPFIF_00504 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KNAKPFIF_00508 1.5e-82 ydcG S EVE domain
KNAKPFIF_00509 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
KNAKPFIF_00510 0.0 yhgF K COG2183 Transcriptional accessory protein
KNAKPFIF_00511 1.6e-84 ydcK S Belongs to the SprT family
KNAKPFIF_00519 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNAKPFIF_00520 2.4e-71 lrpA K transcriptional
KNAKPFIF_00521 3.9e-78 lrpB K transcriptional
KNAKPFIF_00522 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
KNAKPFIF_00523 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
KNAKPFIF_00524 5e-227 ydeG EGP Major facilitator Superfamily
KNAKPFIF_00529 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KNAKPFIF_00530 8.7e-30 cspL K Cold shock
KNAKPFIF_00531 6.1e-79 carD K Transcription factor
KNAKPFIF_00532 4.6e-35 ydzE EG spore germination
KNAKPFIF_00533 1.1e-166 rhaS5 K AraC-like ligand binding domain
KNAKPFIF_00534 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KNAKPFIF_00535 2.5e-166 ydeE K AraC family transcriptional regulator
KNAKPFIF_00536 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNAKPFIF_00537 3.4e-220 ydeG EGP Major facilitator superfamily
KNAKPFIF_00538 2.9e-47 ydeH
KNAKPFIF_00539 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
KNAKPFIF_00540 4e-116
KNAKPFIF_00541 2e-152 ydeK EG -transporter
KNAKPFIF_00542 3.5e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNAKPFIF_00543 2.3e-72 maoC I N-terminal half of MaoC dehydratase
KNAKPFIF_00544 1.3e-102 ydeN S Serine hydrolase
KNAKPFIF_00545 1e-10 K HxlR-like helix-turn-helix
KNAKPFIF_00546 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KNAKPFIF_00547 4.8e-69 ydeP K Transcriptional regulator
KNAKPFIF_00548 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
KNAKPFIF_00549 1.2e-195 ydeR EGP Major facilitator Superfamily
KNAKPFIF_00550 8.4e-105 ydeS K Transcriptional regulator
KNAKPFIF_00551 1.3e-57 arsR K transcriptional
KNAKPFIF_00552 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KNAKPFIF_00553 7.2e-149 ydfB J GNAT acetyltransferase
KNAKPFIF_00554 1e-162 ydfC EG EamA-like transporter family
KNAKPFIF_00555 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNAKPFIF_00556 5.9e-117 ydfE S Flavin reductase like domain
KNAKPFIF_00557 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
KNAKPFIF_00558 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNAKPFIF_00560 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
KNAKPFIF_00561 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNAKPFIF_00562 0.0 ydfJ S drug exporters of the RND superfamily
KNAKPFIF_00563 1.9e-177 S Alpha/beta hydrolase family
KNAKPFIF_00564 5.9e-118 S Protein of unknown function (DUF554)
KNAKPFIF_00565 3.2e-147 K Bacterial transcription activator, effector binding domain
KNAKPFIF_00566 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNAKPFIF_00567 2.6e-109 ydfN C nitroreductase
KNAKPFIF_00568 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KNAKPFIF_00569 8.8e-63 mhqP S DoxX
KNAKPFIF_00570 8.5e-54 traF CO Thioredoxin
KNAKPFIF_00571 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
KNAKPFIF_00572 6.3e-29
KNAKPFIF_00574 4.4e-118 ydfR S Protein of unknown function (DUF421)
KNAKPFIF_00575 5.2e-122 ydfS S Protein of unknown function (DUF421)
KNAKPFIF_00576 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
KNAKPFIF_00577 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
KNAKPFIF_00578 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
KNAKPFIF_00579 1.5e-101 K Bacterial regulatory proteins, tetR family
KNAKPFIF_00580 1.9e-53 S DoxX-like family
KNAKPFIF_00581 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
KNAKPFIF_00582 4.2e-308 expZ S ABC transporter
KNAKPFIF_00583 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KNAKPFIF_00584 4.6e-91 dinB S DinB family
KNAKPFIF_00585 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
KNAKPFIF_00586 0.0 ydgH S drug exporters of the RND superfamily
KNAKPFIF_00587 1e-113 drgA C nitroreductase
KNAKPFIF_00588 1.1e-69 ydgJ K Winged helix DNA-binding domain
KNAKPFIF_00589 2.5e-209 tcaB EGP Major facilitator Superfamily
KNAKPFIF_00590 1.2e-121 ydhB S membrane transporter protein
KNAKPFIF_00591 1.3e-63 ydhC K FCD
KNAKPFIF_00592 3.3e-244 ydhD M Glycosyl hydrolase
KNAKPFIF_00593 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KNAKPFIF_00594 1.9e-127
KNAKPFIF_00595 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KNAKPFIF_00596 4.6e-69 frataxin S Domain of unknown function (DU1801)
KNAKPFIF_00598 4.1e-86 K Acetyltransferase (GNAT) domain
KNAKPFIF_00599 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KNAKPFIF_00600 1.7e-99 ydhK M Protein of unknown function (DUF1541)
KNAKPFIF_00601 4.6e-200 pbuE EGP Major facilitator Superfamily
KNAKPFIF_00602 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KNAKPFIF_00603 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KNAKPFIF_00604 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNAKPFIF_00605 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KNAKPFIF_00606 3.9e-133 ydhQ K UTRA
KNAKPFIF_00607 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KNAKPFIF_00608 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
KNAKPFIF_00609 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KNAKPFIF_00610 8.7e-78 ydhU P Catalase
KNAKPFIF_00611 1.1e-16 ydhU P Manganese containing catalase
KNAKPFIF_00614 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00615 7.8e-08
KNAKPFIF_00617 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KNAKPFIF_00618 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KNAKPFIF_00619 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KNAKPFIF_00620 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KNAKPFIF_00621 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KNAKPFIF_00622 0.0 ydiF S ABC transporter
KNAKPFIF_00623 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KNAKPFIF_00624 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KNAKPFIF_00625 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KNAKPFIF_00626 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KNAKPFIF_00627 2.9e-27 ydiK S Domain of unknown function (DUF4305)
KNAKPFIF_00628 7.9e-129 ydiL S CAAX protease self-immunity
KNAKPFIF_00629 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KNAKPFIF_00630 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KNAKPFIF_00632 6.4e-66 KL Phage plasmid primase P4 family
KNAKPFIF_00633 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KNAKPFIF_00634 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KNAKPFIF_00636 1.2e-199 V AAA domain (dynein-related subfamily)
KNAKPFIF_00637 4.9e-257 J LlaJI restriction endonuclease
KNAKPFIF_00638 1.1e-08 ydjC S Abhydrolase domain containing 18
KNAKPFIF_00639 0.0 K NB-ARC domain
KNAKPFIF_00640 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
KNAKPFIF_00641 3.5e-255 gutA G MFS/sugar transport protein
KNAKPFIF_00642 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KNAKPFIF_00643 5.1e-114 pspA KT Phage shock protein A
KNAKPFIF_00644 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNAKPFIF_00645 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KNAKPFIF_00646 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
KNAKPFIF_00647 4.7e-196 S Ion transport 2 domain protein
KNAKPFIF_00648 2.7e-258 iolT EGP Major facilitator Superfamily
KNAKPFIF_00649 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KNAKPFIF_00650 4.5e-64 ydjM M Lytic transglycolase
KNAKPFIF_00651 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
KNAKPFIF_00653 1.4e-34 ydjO S Cold-inducible protein YdjO
KNAKPFIF_00654 9.5e-160 ydjP I Alpha/beta hydrolase family
KNAKPFIF_00655 2.4e-181 yeaA S Protein of unknown function (DUF4003)
KNAKPFIF_00656 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KNAKPFIF_00657 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KNAKPFIF_00658 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KNAKPFIF_00659 1.6e-177 yeaC S COG0714 MoxR-like ATPases
KNAKPFIF_00660 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KNAKPFIF_00661 0.0 yebA E COG1305 Transglutaminase-like enzymes
KNAKPFIF_00662 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KNAKPFIF_00663 6e-212 pbuG S permease
KNAKPFIF_00664 1.1e-118 yebC M Membrane
KNAKPFIF_00666 4e-93 yebE S UPF0316 protein
KNAKPFIF_00667 8e-28 yebG S NETI protein
KNAKPFIF_00668 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KNAKPFIF_00669 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KNAKPFIF_00670 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KNAKPFIF_00671 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KNAKPFIF_00672 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNAKPFIF_00673 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNAKPFIF_00674 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KNAKPFIF_00675 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KNAKPFIF_00676 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KNAKPFIF_00677 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KNAKPFIF_00678 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KNAKPFIF_00679 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
KNAKPFIF_00680 3.5e-73 K helix_turn_helix ASNC type
KNAKPFIF_00681 2.3e-232 yjeH E Amino acid permease
KNAKPFIF_00682 2.7e-27 S Protein of unknown function (DUF2892)
KNAKPFIF_00683 0.0 yerA 3.5.4.2 F adenine deaminase
KNAKPFIF_00684 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
KNAKPFIF_00685 4.8e-51 yerC S protein conserved in bacteria
KNAKPFIF_00686 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KNAKPFIF_00688 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KNAKPFIF_00689 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KNAKPFIF_00690 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KNAKPFIF_00691 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
KNAKPFIF_00692 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
KNAKPFIF_00693 1.6e-123 sapB S MgtC SapB transporter
KNAKPFIF_00694 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNAKPFIF_00695 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNAKPFIF_00696 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KNAKPFIF_00697 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KNAKPFIF_00698 4e-156 yerO K Transcriptional regulator
KNAKPFIF_00699 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KNAKPFIF_00700 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KNAKPFIF_00701 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNAKPFIF_00702 3.2e-98 L Recombinase
KNAKPFIF_00703 3.2e-53 L Resolvase, N terminal domain
KNAKPFIF_00704 0.0 yeeA V Type II restriction enzyme, methylase subunits
KNAKPFIF_00705 0.0 yeeB L DEAD-like helicases superfamily
KNAKPFIF_00706 1.8e-212 pstS P T5orf172
KNAKPFIF_00708 6.2e-31 S Colicin immunity protein / pyocin immunity protein
KNAKPFIF_00709 5.5e-83 S Protein of unknown function, DUF600
KNAKPFIF_00710 0.0 L nucleic acid phosphodiester bond hydrolysis
KNAKPFIF_00711 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
KNAKPFIF_00712 5.5e-214 S Tetratricopeptide repeat
KNAKPFIF_00714 9.4e-127 yeeN K transcriptional regulatory protein
KNAKPFIF_00716 1.2e-103 dhaR3 K Transcriptional regulator
KNAKPFIF_00717 9.7e-82 yesE S SnoaL-like domain
KNAKPFIF_00718 2.2e-159 yesF GM NAD(P)H-binding
KNAKPFIF_00719 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
KNAKPFIF_00720 1.5e-45 cotJB S CotJB protein
KNAKPFIF_00721 5.2e-104 cotJC P Spore Coat
KNAKPFIF_00722 4.2e-103 yesJ K Acetyltransferase (GNAT) family
KNAKPFIF_00724 4.4e-104 yesL S Protein of unknown function, DUF624
KNAKPFIF_00725 0.0 yesM 2.7.13.3 T Histidine kinase
KNAKPFIF_00726 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
KNAKPFIF_00727 5e-248 yesO G Bacterial extracellular solute-binding protein
KNAKPFIF_00728 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
KNAKPFIF_00729 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
KNAKPFIF_00730 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
KNAKPFIF_00731 0.0 yesS K Transcriptional regulator
KNAKPFIF_00732 3.8e-133 E GDSL-like Lipase/Acylhydrolase
KNAKPFIF_00733 8.9e-132 yesU S Domain of unknown function (DUF1961)
KNAKPFIF_00734 1e-113 yesV S Protein of unknown function, DUF624
KNAKPFIF_00735 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KNAKPFIF_00736 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KNAKPFIF_00737 1.7e-108 yesY E GDSL-like Lipase/Acylhydrolase
KNAKPFIF_00738 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
KNAKPFIF_00739 0.0 yetA
KNAKPFIF_00740 9.6e-291 lplA G Bacterial extracellular solute-binding protein
KNAKPFIF_00741 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KNAKPFIF_00742 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
KNAKPFIF_00743 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KNAKPFIF_00744 6.1e-123 yetF S membrane
KNAKPFIF_00745 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KNAKPFIF_00746 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNAKPFIF_00747 2.2e-34
KNAKPFIF_00748 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KNAKPFIF_00749 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KNAKPFIF_00750 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
KNAKPFIF_00751 5.3e-105 yetJ S Belongs to the BI1 family
KNAKPFIF_00752 5.4e-159 yetK EG EamA-like transporter family
KNAKPFIF_00753 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
KNAKPFIF_00754 7.8e-213 yetM CH FAD binding domain
KNAKPFIF_00755 3.6e-199 yetN S Protein of unknown function (DUF3900)
KNAKPFIF_00756 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KNAKPFIF_00757 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KNAKPFIF_00758 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
KNAKPFIF_00759 1.9e-172 yfnG 4.2.1.45 M dehydratase
KNAKPFIF_00760 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
KNAKPFIF_00761 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KNAKPFIF_00762 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
KNAKPFIF_00763 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
KNAKPFIF_00764 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KNAKPFIF_00765 1.3e-241 yfnA E amino acid
KNAKPFIF_00766 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KNAKPFIF_00767 1.1e-113 yfmS NT chemotaxis protein
KNAKPFIF_00768 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KNAKPFIF_00769 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
KNAKPFIF_00770 2.8e-70 yfmP K transcriptional
KNAKPFIF_00771 1.5e-209 yfmO EGP Major facilitator Superfamily
KNAKPFIF_00772 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KNAKPFIF_00773 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KNAKPFIF_00774 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
KNAKPFIF_00775 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
KNAKPFIF_00776 7.7e-214 G Major Facilitator Superfamily
KNAKPFIF_00777 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
KNAKPFIF_00778 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
KNAKPFIF_00779 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_00780 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_00781 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KNAKPFIF_00782 2.9e-24 S Protein of unknown function (DUF3212)
KNAKPFIF_00783 7.6e-58 yflT S Heat induced stress protein YflT
KNAKPFIF_00784 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KNAKPFIF_00785 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
KNAKPFIF_00786 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KNAKPFIF_00787 8.9e-119 citT T response regulator
KNAKPFIF_00788 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
KNAKPFIF_00790 8.5e-227 citM C Citrate transporter
KNAKPFIF_00791 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KNAKPFIF_00792 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KNAKPFIF_00793 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KNAKPFIF_00794 9e-124 yflK S protein conserved in bacteria
KNAKPFIF_00795 4e-18 yflJ S Protein of unknown function (DUF2639)
KNAKPFIF_00796 4.1e-19 yflI
KNAKPFIF_00797 2.4e-50 yflH S Protein of unknown function (DUF3243)
KNAKPFIF_00798 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
KNAKPFIF_00799 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KNAKPFIF_00800 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KNAKPFIF_00801 6e-67 yhdN S Domain of unknown function (DUF1992)
KNAKPFIF_00802 3.2e-256 agcS_1 E Sodium alanine symporter
KNAKPFIF_00803 1.6e-194 E Spore germination protein
KNAKPFIF_00805 5.1e-207 yfkR S spore germination
KNAKPFIF_00806 1.5e-283 yfkQ EG Spore germination protein
KNAKPFIF_00807 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KNAKPFIF_00808 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KNAKPFIF_00809 1.8e-133 treR K transcriptional
KNAKPFIF_00810 1.6e-125 yfkO C nitroreductase
KNAKPFIF_00811 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KNAKPFIF_00812 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
KNAKPFIF_00813 6.8e-207 ydiM EGP Major facilitator Superfamily
KNAKPFIF_00814 2.1e-29 yfkK S Belongs to the UPF0435 family
KNAKPFIF_00815 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNAKPFIF_00816 8.4e-51 yfkI S gas vesicle protein
KNAKPFIF_00817 9.7e-144 yihY S Belongs to the UPF0761 family
KNAKPFIF_00818 5e-08
KNAKPFIF_00819 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KNAKPFIF_00820 6.1e-183 cax P COG0387 Ca2 H antiporter
KNAKPFIF_00821 1.2e-146 yfkD S YfkD-like protein
KNAKPFIF_00822 6e-149 yfkC M Mechanosensitive ion channel
KNAKPFIF_00823 5.4e-222 yfkA S YfkB-like domain
KNAKPFIF_00824 1.1e-26 yfjT
KNAKPFIF_00825 2.6e-154 pdaA G deacetylase
KNAKPFIF_00826 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KNAKPFIF_00827 1.7e-184 corA P Mediates influx of magnesium ions
KNAKPFIF_00828 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KNAKPFIF_00829 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KNAKPFIF_00830 1.6e-39 S YfzA-like protein
KNAKPFIF_00831 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KNAKPFIF_00832 3.9e-86 yfjM S Psort location Cytoplasmic, score
KNAKPFIF_00833 3e-29 yfjL
KNAKPFIF_00834 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KNAKPFIF_00835 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KNAKPFIF_00836 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KNAKPFIF_00837 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KNAKPFIF_00838 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KNAKPFIF_00839 1.2e-25 sspH S Belongs to the SspH family
KNAKPFIF_00840 4e-56 yfjF S UPF0060 membrane protein
KNAKPFIF_00841 1.3e-80 S Family of unknown function (DUF5381)
KNAKPFIF_00842 1.8e-101 yfjD S Family of unknown function (DUF5381)
KNAKPFIF_00843 4.1e-144 yfjC
KNAKPFIF_00844 9.2e-191 yfjB
KNAKPFIF_00845 1.1e-44 yfjA S Belongs to the WXG100 family
KNAKPFIF_00846 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KNAKPFIF_00847 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
KNAKPFIF_00848 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KNAKPFIF_00849 2.1e-310 yfiB3 V ABC transporter
KNAKPFIF_00850 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KNAKPFIF_00851 8.3e-64 mhqP S DoxX
KNAKPFIF_00852 7.4e-163 yfiE 1.13.11.2 S glyoxalase
KNAKPFIF_00853 1.5e-177 K AraC-like ligand binding domain
KNAKPFIF_00854 1.8e-262 iolT EGP Major facilitator Superfamily
KNAKPFIF_00855 8.4e-184 G Xylose isomerase
KNAKPFIF_00856 1.1e-233 S Oxidoreductase
KNAKPFIF_00858 1.1e-214 yxjM T Histidine kinase
KNAKPFIF_00859 3.2e-113 KT LuxR family transcriptional regulator
KNAKPFIF_00860 6.2e-171 V ABC transporter, ATP-binding protein
KNAKPFIF_00861 9.8e-214 V ABC-2 family transporter protein
KNAKPFIF_00862 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
KNAKPFIF_00863 8.3e-99 padR K transcriptional
KNAKPFIF_00864 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KNAKPFIF_00865 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KNAKPFIF_00866 2e-109 yfiR K Transcriptional regulator
KNAKPFIF_00867 5.1e-221 yfiS EGP Major facilitator Superfamily
KNAKPFIF_00868 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
KNAKPFIF_00869 8.7e-287 yfiU EGP Major facilitator Superfamily
KNAKPFIF_00870 3.1e-81 yfiV K transcriptional
KNAKPFIF_00871 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KNAKPFIF_00872 6.2e-182 yfiY P ABC transporter substrate-binding protein
KNAKPFIF_00873 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_00874 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_00875 1.8e-167 yfhB 5.3.3.17 S PhzF family
KNAKPFIF_00876 3.9e-107 yfhC C nitroreductase
KNAKPFIF_00877 2.1e-25 yfhD S YfhD-like protein
KNAKPFIF_00879 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
KNAKPFIF_00880 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
KNAKPFIF_00881 9.7e-52 yfhH S Protein of unknown function (DUF1811)
KNAKPFIF_00883 1.1e-209 yfhI EGP Major facilitator Superfamily
KNAKPFIF_00884 6.2e-20 sspK S reproduction
KNAKPFIF_00885 1.3e-44 yfhJ S WVELL protein
KNAKPFIF_00886 9.2e-92 batE T Bacterial SH3 domain homologues
KNAKPFIF_00887 3.5e-51 yfhL S SdpI/YhfL protein family
KNAKPFIF_00888 6.7e-172 yfhM S Alpha beta hydrolase
KNAKPFIF_00889 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KNAKPFIF_00890 0.0 yfhO S Bacterial membrane protein YfhO
KNAKPFIF_00891 5.5e-186 yfhP S membrane-bound metal-dependent
KNAKPFIF_00892 7.8e-212 mutY L A G-specific
KNAKPFIF_00893 6.9e-36 yfhS
KNAKPFIF_00894 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_00895 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
KNAKPFIF_00896 1.5e-37 ygaB S YgaB-like protein
KNAKPFIF_00897 1.3e-104 ygaC J Belongs to the UPF0374 family
KNAKPFIF_00898 1.8e-301 ygaD V ABC transporter
KNAKPFIF_00899 8.7e-180 ygaE S Membrane
KNAKPFIF_00900 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KNAKPFIF_00901 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
KNAKPFIF_00902 4e-80 perR P Belongs to the Fur family
KNAKPFIF_00903 1.5e-56 ygzB S UPF0295 protein
KNAKPFIF_00904 6.7e-167 ygxA S Nucleotidyltransferase-like
KNAKPFIF_00905 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_00910 7.8e-08
KNAKPFIF_00918 2e-08
KNAKPFIF_00922 2.7e-143 spo0M S COG4326 Sporulation control protein
KNAKPFIF_00923 3e-27
KNAKPFIF_00924 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KNAKPFIF_00926 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KNAKPFIF_00927 1.9e-266 ygaK C Berberine and berberine like
KNAKPFIF_00929 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KNAKPFIF_00930 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KNAKPFIF_00931 1.7e-171 ssuA M Sulfonate ABC transporter
KNAKPFIF_00932 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KNAKPFIF_00933 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KNAKPFIF_00935 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KNAKPFIF_00936 4.1e-78 ygaO
KNAKPFIF_00937 4.4e-29 K Transcriptional regulator
KNAKPFIF_00939 7.9e-114 yhzB S B3/4 domain
KNAKPFIF_00940 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KNAKPFIF_00941 4.4e-177 yhbB S Putative amidase domain
KNAKPFIF_00942 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KNAKPFIF_00943 1.2e-109 yhbD K Protein of unknown function (DUF4004)
KNAKPFIF_00944 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KNAKPFIF_00945 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KNAKPFIF_00946 0.0 prkA T Ser protein kinase
KNAKPFIF_00947 2.5e-225 yhbH S Belongs to the UPF0229 family
KNAKPFIF_00948 2.2e-76 yhbI K DNA-binding transcription factor activity
KNAKPFIF_00949 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
KNAKPFIF_00950 3.1e-271 yhcA EGP Major facilitator Superfamily
KNAKPFIF_00951 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
KNAKPFIF_00952 2.8e-37 yhcC
KNAKPFIF_00953 7.8e-55
KNAKPFIF_00954 6.6e-60 yhcF K Transcriptional regulator
KNAKPFIF_00955 1.6e-123 yhcG V ABC transporter, ATP-binding protein
KNAKPFIF_00956 2.6e-166 yhcH V ABC transporter, ATP-binding protein
KNAKPFIF_00957 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KNAKPFIF_00958 1e-30 cspB K Cold-shock protein
KNAKPFIF_00959 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
KNAKPFIF_00960 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KNAKPFIF_00961 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KNAKPFIF_00962 1.2e-39 yhcM
KNAKPFIF_00963 2.2e-62 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KNAKPFIF_00964 9.1e-160 yhcP
KNAKPFIF_00965 7.2e-86 yhcQ M Spore coat protein
KNAKPFIF_00966 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
KNAKPFIF_00967 1e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KNAKPFIF_00968 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KNAKPFIF_00969 9.3e-68 yhcU S Family of unknown function (DUF5365)
KNAKPFIF_00970 3.8e-67 yhcV S COG0517 FOG CBS domain
KNAKPFIF_00971 1e-119 yhcW 5.4.2.6 S hydrolase
KNAKPFIF_00972 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KNAKPFIF_00973 4.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KNAKPFIF_00974 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KNAKPFIF_00975 1.7e-151 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KNAKPFIF_00976 1.3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KNAKPFIF_00977 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KNAKPFIF_00978 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KNAKPFIF_00979 4e-212 yhcY 2.7.13.3 T Histidine kinase
KNAKPFIF_00980 3.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNAKPFIF_00981 2.1e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
KNAKPFIF_00982 1.2e-38 yhdB S YhdB-like protein
KNAKPFIF_00983 1.8e-53 yhdC S Protein of unknown function (DUF3889)
KNAKPFIF_00984 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KNAKPFIF_00985 1e-75 nsrR K Transcriptional regulator
KNAKPFIF_00986 1.5e-238 ygxB M Conserved TM helix
KNAKPFIF_00987 6.3e-276 ycgB S Stage V sporulation protein R
KNAKPFIF_00988 1.1e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KNAKPFIF_00989 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KNAKPFIF_00990 3.8e-162 citR K Transcriptional regulator
KNAKPFIF_00991 3.2e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
KNAKPFIF_00992 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_00993 3.4e-250 yhdG E amino acid
KNAKPFIF_00994 3.7e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KNAKPFIF_00995 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNAKPFIF_00996 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNAKPFIF_00997 8.1e-45 yhdK S Sigma-M inhibitor protein
KNAKPFIF_00998 3.3e-200 yhdL S Sigma factor regulator N-terminal
KNAKPFIF_00999 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_01000 5.7e-191 yhdN C Aldo keto reductase
KNAKPFIF_01001 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KNAKPFIF_01002 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KNAKPFIF_01003 4.1e-74 cueR K transcriptional
KNAKPFIF_01004 6.4e-73 yhdR 2.6.1.1 E Aminotransferase
KNAKPFIF_01005 1.9e-135 yhdR 2.6.1.1 E Aminotransferase
KNAKPFIF_01006 2.3e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KNAKPFIF_01007 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNAKPFIF_01008 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KNAKPFIF_01009 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KNAKPFIF_01011 2.1e-202 yhdY M Mechanosensitive ion channel
KNAKPFIF_01012 1.1e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KNAKPFIF_01013 7.4e-147 yheN G deacetylase
KNAKPFIF_01014 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KNAKPFIF_01015 5.7e-226 nhaC C Na H antiporter
KNAKPFIF_01016 1.5e-83 nhaX T Belongs to the universal stress protein A family
KNAKPFIF_01017 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KNAKPFIF_01018 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KNAKPFIF_01019 4.5e-109 yheG GM NAD(P)H-binding
KNAKPFIF_01020 6.3e-28 sspB S spore protein
KNAKPFIF_01021 1.3e-36 yheE S Family of unknown function (DUF5342)
KNAKPFIF_01022 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KNAKPFIF_01023 4.3e-216 yheC HJ YheC/D like ATP-grasp
KNAKPFIF_01024 6.7e-204 yheB S Belongs to the UPF0754 family
KNAKPFIF_01025 9.5e-48 yheA S Belongs to the UPF0342 family
KNAKPFIF_01026 3.1e-206 yhaZ L DNA alkylation repair enzyme
KNAKPFIF_01027 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
KNAKPFIF_01028 1.8e-292 hemZ H coproporphyrinogen III oxidase
KNAKPFIF_01029 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
KNAKPFIF_01030 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KNAKPFIF_01032 6.4e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
KNAKPFIF_01033 3.2e-26 S YhzD-like protein
KNAKPFIF_01034 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
KNAKPFIF_01035 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KNAKPFIF_01036 3.6e-227 yhaO L DNA repair exonuclease
KNAKPFIF_01037 0.0 yhaN L AAA domain
KNAKPFIF_01038 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KNAKPFIF_01039 1.6e-21 yhaL S Sporulation protein YhaL
KNAKPFIF_01040 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KNAKPFIF_01041 8.7e-90 yhaK S Putative zincin peptidase
KNAKPFIF_01042 1.3e-54 yhaI S Protein of unknown function (DUF1878)
KNAKPFIF_01043 1e-113 hpr K Negative regulator of protease production and sporulation
KNAKPFIF_01044 7e-39 yhaH S YtxH-like protein
KNAKPFIF_01045 3.6e-80 trpP S Tryptophan transporter TrpP
KNAKPFIF_01046 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KNAKPFIF_01047 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KNAKPFIF_01048 4.6e-137 ecsA V transporter (ATP-binding protein)
KNAKPFIF_01049 4.5e-214 ecsB U ABC transporter
KNAKPFIF_01050 1e-112 ecsC S EcsC protein family
KNAKPFIF_01051 1e-226 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KNAKPFIF_01052 1.6e-244 yhfA C membrane
KNAKPFIF_01053 1.6e-33 1.15.1.2 C Rubrerythrin
KNAKPFIF_01054 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KNAKPFIF_01055 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KNAKPFIF_01056 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KNAKPFIF_01057 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KNAKPFIF_01058 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KNAKPFIF_01059 1.4e-101 yhgD K Transcriptional regulator
KNAKPFIF_01060 1e-238 yhgE S YhgE Pip N-terminal domain protein
KNAKPFIF_01061 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNAKPFIF_01062 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
KNAKPFIF_01063 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KNAKPFIF_01064 1.7e-72 3.4.13.21 S ASCH
KNAKPFIF_01065 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KNAKPFIF_01066 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KNAKPFIF_01067 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
KNAKPFIF_01068 2.9e-111 yhfK GM NmrA-like family
KNAKPFIF_01069 3.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KNAKPFIF_01070 1.3e-64 yhfM
KNAKPFIF_01071 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
KNAKPFIF_01072 5.2e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KNAKPFIF_01073 9.2e-80 VY92_01935 K acetyltransferase
KNAKPFIF_01074 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
KNAKPFIF_01075 4.3e-159 yfmC M Periplasmic binding protein
KNAKPFIF_01076 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KNAKPFIF_01077 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
KNAKPFIF_01078 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KNAKPFIF_01079 5e-91 bioY S BioY family
KNAKPFIF_01080 1.7e-182 hemAT NT chemotaxis protein
KNAKPFIF_01081 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KNAKPFIF_01082 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_01083 1.3e-32 yhzC S IDEAL
KNAKPFIF_01084 4.2e-109 comK K Competence transcription factor
KNAKPFIF_01085 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
KNAKPFIF_01086 7.8e-42 yhjA S Excalibur calcium-binding domain
KNAKPFIF_01087 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNAKPFIF_01088 6.9e-27 yhjC S Protein of unknown function (DUF3311)
KNAKPFIF_01089 5e-60 yhjD
KNAKPFIF_01090 9.1e-110 yhjE S SNARE associated Golgi protein
KNAKPFIF_01091 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KNAKPFIF_01092 1.1e-286 yhjG CH FAD binding domain
KNAKPFIF_01093 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
KNAKPFIF_01094 6.9e-215 glcP G Major Facilitator Superfamily
KNAKPFIF_01095 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
KNAKPFIF_01096 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
KNAKPFIF_01097 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KNAKPFIF_01098 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
KNAKPFIF_01099 3.8e-202 abrB S membrane
KNAKPFIF_01100 3.1e-215 EGP Transmembrane secretion effector
KNAKPFIF_01101 0.0 S Sugar transport-related sRNA regulator N-term
KNAKPFIF_01102 1.9e-34 yhjQ C COG1145 Ferredoxin
KNAKPFIF_01103 2.2e-78 yhjR S Rubrerythrin
KNAKPFIF_01104 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KNAKPFIF_01105 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KNAKPFIF_01106 2.8e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KNAKPFIF_01107 0.0 sbcC L COG0419 ATPase involved in DNA repair
KNAKPFIF_01108 6e-51 yisB V COG1403 Restriction endonuclease
KNAKPFIF_01109 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
KNAKPFIF_01110 3e-66 gerPE S Spore germination protein GerPE
KNAKPFIF_01111 6.3e-24 gerPD S Spore germination protein
KNAKPFIF_01112 1.8e-54 gerPC S Spore germination protein
KNAKPFIF_01113 4e-34 gerPB S cell differentiation
KNAKPFIF_01114 1.9e-33 gerPA S Spore germination protein
KNAKPFIF_01115 1.5e-22 yisI S Spo0E like sporulation regulatory protein
KNAKPFIF_01116 1.7e-176 cotH M Spore Coat
KNAKPFIF_01117 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KNAKPFIF_01118 3e-57 yisL S UPF0344 protein
KNAKPFIF_01119 0.0 wprA O Belongs to the peptidase S8 family
KNAKPFIF_01120 7.2e-106 yisN S Protein of unknown function (DUF2777)
KNAKPFIF_01121 0.0 asnO 6.3.5.4 E Asparagine synthase
KNAKPFIF_01122 2.1e-88 yizA S Damage-inducible protein DinB
KNAKPFIF_01123 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KNAKPFIF_01124 4e-243 yisQ V Mate efflux family protein
KNAKPFIF_01125 1.4e-161 yisR K Transcriptional regulator
KNAKPFIF_01126 2.4e-184 purR K helix_turn _helix lactose operon repressor
KNAKPFIF_01127 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KNAKPFIF_01128 1.3e-93 yisT S DinB family
KNAKPFIF_01129 6.4e-108 argO S Lysine exporter protein LysE YggA
KNAKPFIF_01130 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KNAKPFIF_01131 4e-36 mcbG S Pentapeptide repeats (9 copies)
KNAKPFIF_01132 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KNAKPFIF_01133 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KNAKPFIF_01134 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KNAKPFIF_01135 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KNAKPFIF_01136 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
KNAKPFIF_01137 1.9e-141 yitD 4.4.1.19 S synthase
KNAKPFIF_01138 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNAKPFIF_01139 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KNAKPFIF_01140 4e-229 yitG EGP Major facilitator Superfamily
KNAKPFIF_01141 1.8e-161 yitH K Acetyltransferase (GNAT) domain
KNAKPFIF_01142 2e-82 yjcF S Acetyltransferase (GNAT) domain
KNAKPFIF_01143 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KNAKPFIF_01144 8.6e-55 yajQ S Belongs to the UPF0234 family
KNAKPFIF_01145 4e-161 cvfB S protein conserved in bacteria
KNAKPFIF_01146 8.5e-94
KNAKPFIF_01147 2.8e-171
KNAKPFIF_01148 1.5e-97 S Sporulation delaying protein SdpA
KNAKPFIF_01149 1.5e-58 K Transcriptional regulator PadR-like family
KNAKPFIF_01150 2e-95
KNAKPFIF_01151 1.4e-44 yitR S Domain of unknown function (DUF3784)
KNAKPFIF_01152 2.2e-311 nprB 3.4.24.28 E Peptidase M4
KNAKPFIF_01153 8.4e-159 yitS S protein conserved in bacteria
KNAKPFIF_01154 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KNAKPFIF_01155 1.9e-72 ipi S Intracellular proteinase inhibitor
KNAKPFIF_01156 1.2e-17 S Protein of unknown function (DUF3813)
KNAKPFIF_01157 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KNAKPFIF_01158 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KNAKPFIF_01159 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KNAKPFIF_01160 1.5e-22 pilT S Proteolipid membrane potential modulator
KNAKPFIF_01161 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
KNAKPFIF_01162 1.7e-88 norB G Major Facilitator Superfamily
KNAKPFIF_01163 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KNAKPFIF_01164 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KNAKPFIF_01165 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KNAKPFIF_01166 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KNAKPFIF_01167 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KNAKPFIF_01168 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KNAKPFIF_01169 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KNAKPFIF_01170 9.5e-28 yjzC S YjzC-like protein
KNAKPFIF_01171 2.3e-16 yjzD S Protein of unknown function (DUF2929)
KNAKPFIF_01172 6.2e-142 yjaU I carboxylic ester hydrolase activity
KNAKPFIF_01173 7.3e-103 yjaV
KNAKPFIF_01174 1.1e-183 med S Transcriptional activator protein med
KNAKPFIF_01175 7.3e-26 comZ S ComZ
KNAKPFIF_01176 2.7e-22 yjzB
KNAKPFIF_01177 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KNAKPFIF_01178 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KNAKPFIF_01179 7.8e-151 yjaZ O Zn-dependent protease
KNAKPFIF_01180 1.8e-184 appD P Belongs to the ABC transporter superfamily
KNAKPFIF_01181 6.5e-187 appF E Belongs to the ABC transporter superfamily
KNAKPFIF_01182 3.5e-48 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KNAKPFIF_01183 1.9e-190 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KNAKPFIF_01184 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNAKPFIF_01185 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNAKPFIF_01186 5e-147 yjbA S Belongs to the UPF0736 family
KNAKPFIF_01187 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KNAKPFIF_01188 0.0 oppA E ABC transporter substrate-binding protein
KNAKPFIF_01189 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNAKPFIF_01190 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNAKPFIF_01191 3e-198 oppD P Belongs to the ABC transporter superfamily
KNAKPFIF_01192 5.5e-172 oppF E Belongs to the ABC transporter superfamily
KNAKPFIF_01193 8.6e-196 yjbB EGP Major Facilitator Superfamily
KNAKPFIF_01194 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNAKPFIF_01195 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KNAKPFIF_01196 6e-112 yjbE P Integral membrane protein TerC family
KNAKPFIF_01197 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KNAKPFIF_01198 2.3e-223 yjbF S Competence protein
KNAKPFIF_01199 0.0 pepF E oligoendopeptidase F
KNAKPFIF_01200 1.8e-20
KNAKPFIF_01202 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KNAKPFIF_01203 3.7e-72 yjbI S Bacterial-like globin
KNAKPFIF_01204 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KNAKPFIF_01205 2.4e-101 yjbK S protein conserved in bacteria
KNAKPFIF_01206 7.1e-62 yjbL S Belongs to the UPF0738 family
KNAKPFIF_01207 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
KNAKPFIF_01208 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KNAKPFIF_01209 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KNAKPFIF_01210 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KNAKPFIF_01211 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KNAKPFIF_01212 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KNAKPFIF_01213 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KNAKPFIF_01214 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
KNAKPFIF_01215 3e-30 thiS H thiamine diphosphate biosynthetic process
KNAKPFIF_01216 1.3e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KNAKPFIF_01217 4.3e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KNAKPFIF_01218 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KNAKPFIF_01219 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KNAKPFIF_01220 5.9e-54 yjbX S Spore coat protein
KNAKPFIF_01221 5.2e-83 cotZ S Spore coat protein
KNAKPFIF_01222 3.4e-96 cotY S Spore coat protein Z
KNAKPFIF_01223 6.4e-77 cotX S Spore Coat Protein X and V domain
KNAKPFIF_01224 3e-32 cotW
KNAKPFIF_01225 2.3e-55 cotV S Spore Coat Protein X and V domain
KNAKPFIF_01226 8.7e-57 yjcA S Protein of unknown function (DUF1360)
KNAKPFIF_01229 2.9e-38 spoVIF S Stage VI sporulation protein F
KNAKPFIF_01230 0.0 yjcD 3.6.4.12 L DNA helicase
KNAKPFIF_01231 1.7e-38
KNAKPFIF_01232 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNAKPFIF_01233 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KNAKPFIF_01234 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
KNAKPFIF_01235 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KNAKPFIF_01236 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KNAKPFIF_01237 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
KNAKPFIF_01238 1.1e-212 yjcL S Protein of unknown function (DUF819)
KNAKPFIF_01241 2.1e-190 S Putative amidase domain
KNAKPFIF_01242 2.6e-44 yjcN
KNAKPFIF_01245 8.5e-81 L Transposase
KNAKPFIF_01246 1.6e-72 yjcP
KNAKPFIF_01247 4.1e-49 S YjcQ protein
KNAKPFIF_01248 1.1e-92 yqaS L DNA packaging
KNAKPFIF_01249 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
KNAKPFIF_01250 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
KNAKPFIF_01252 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KNAKPFIF_01253 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KNAKPFIF_01254 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KNAKPFIF_01255 4.8e-51 yjdF S Protein of unknown function (DUF2992)
KNAKPFIF_01256 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
KNAKPFIF_01258 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KNAKPFIF_01259 4.2e-29 S Domain of unknown function (DUF4177)
KNAKPFIF_01260 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
KNAKPFIF_01261 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KNAKPFIF_01263 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
KNAKPFIF_01264 5.5e-83 S Protein of unknown function (DUF2690)
KNAKPFIF_01265 3.6e-21 yjfB S Putative motility protein
KNAKPFIF_01266 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
KNAKPFIF_01267 1.2e-45 T PhoQ Sensor
KNAKPFIF_01268 8.9e-104 yjgB S Domain of unknown function (DUF4309)
KNAKPFIF_01269 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KNAKPFIF_01270 4.3e-95 yjgD S Protein of unknown function (DUF1641)
KNAKPFIF_01271 8.7e-07 S Domain of unknown function (DUF4352)
KNAKPFIF_01272 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KNAKPFIF_01274 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KNAKPFIF_01275 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KNAKPFIF_01276 8.2e-30
KNAKPFIF_01277 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KNAKPFIF_01278 1.9e-122 ybbM S transport system, permease component
KNAKPFIF_01279 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
KNAKPFIF_01280 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
KNAKPFIF_01281 2.8e-93 yjlB S Cupin domain
KNAKPFIF_01282 7.1e-66 yjlC S Protein of unknown function (DUF1641)
KNAKPFIF_01283 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
KNAKPFIF_01284 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
KNAKPFIF_01285 5.8e-250 yjmB G symporter YjmB
KNAKPFIF_01286 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KNAKPFIF_01287 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KNAKPFIF_01288 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KNAKPFIF_01289 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_01290 3.7e-227 exuT G Sugar (and other) transporter
KNAKPFIF_01291 2.3e-184 exuR K transcriptional
KNAKPFIF_01292 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KNAKPFIF_01293 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KNAKPFIF_01294 4.3e-130 MA20_18170 S membrane transporter protein
KNAKPFIF_01295 3.3e-80 yjoA S DinB family
KNAKPFIF_01296 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KNAKPFIF_01297 2.1e-213 S response regulator aspartate phosphatase
KNAKPFIF_01299 6.3e-41 S YCII-related domain
KNAKPFIF_01300 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
KNAKPFIF_01301 2.1e-61 yjqA S Bacterial PH domain
KNAKPFIF_01302 4.2e-112 yjqB S Pfam:DUF867
KNAKPFIF_01303 4.4e-160 ydbD P Catalase
KNAKPFIF_01304 1.6e-111 xkdA E IrrE N-terminal-like domain
KNAKPFIF_01305 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
KNAKPFIF_01307 5.9e-157 xkdB K sequence-specific DNA binding
KNAKPFIF_01308 6.4e-119 xkdC L Bacterial dnaA protein
KNAKPFIF_01311 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
KNAKPFIF_01312 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KNAKPFIF_01313 4.8e-140 xtmA L phage terminase small subunit
KNAKPFIF_01314 9.6e-255 xtmB S phage terminase, large subunit
KNAKPFIF_01315 5.4e-286 yqbA S portal protein
KNAKPFIF_01316 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KNAKPFIF_01317 5.8e-169 xkdG S Phage capsid family
KNAKPFIF_01318 5.5e-65 yqbG S Protein of unknown function (DUF3199)
KNAKPFIF_01319 8.7e-65 yqbH S Domain of unknown function (DUF3599)
KNAKPFIF_01320 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
KNAKPFIF_01321 1.9e-77 xkdJ
KNAKPFIF_01322 2.5e-256 xkdK S Phage tail sheath C-terminal domain
KNAKPFIF_01323 6.1e-76 xkdM S Phage tail tube protein
KNAKPFIF_01324 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
KNAKPFIF_01325 0.0 xkdO L Transglycosylase SLT domain
KNAKPFIF_01326 3.7e-122 xkdP S Lysin motif
KNAKPFIF_01327 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
KNAKPFIF_01328 2.1e-39 xkdR S Protein of unknown function (DUF2577)
KNAKPFIF_01329 9.6e-71 xkdS S Protein of unknown function (DUF2634)
KNAKPFIF_01330 1.2e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KNAKPFIF_01331 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KNAKPFIF_01332 6.7e-41
KNAKPFIF_01333 0.0
KNAKPFIF_01334 2.6e-55 xkdW S XkdW protein
KNAKPFIF_01335 1.7e-23 xkdX
KNAKPFIF_01336 1.2e-154 xepA
KNAKPFIF_01337 2.8e-39 xhlA S Haemolysin XhlA
KNAKPFIF_01338 9.3e-40 xhlB S SPP1 phage holin
KNAKPFIF_01339 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KNAKPFIF_01340 6.7e-23 spoIISB S Stage II sporulation protein SB
KNAKPFIF_01341 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KNAKPFIF_01342 5.8e-175 pit P phosphate transporter
KNAKPFIF_01343 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KNAKPFIF_01344 9.4e-242 steT E amino acid
KNAKPFIF_01345 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KNAKPFIF_01347 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KNAKPFIF_01348 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KNAKPFIF_01350 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNAKPFIF_01351 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
KNAKPFIF_01352 7.9e-154 dppA E D-aminopeptidase
KNAKPFIF_01353 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNAKPFIF_01354 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KNAKPFIF_01355 3.4e-191 dppD P Belongs to the ABC transporter superfamily
KNAKPFIF_01356 0.0 dppE E ABC transporter substrate-binding protein
KNAKPFIF_01358 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KNAKPFIF_01359 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KNAKPFIF_01360 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KNAKPFIF_01361 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
KNAKPFIF_01362 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
KNAKPFIF_01363 5.3e-161 ykgA E Amidinotransferase
KNAKPFIF_01364 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KNAKPFIF_01365 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KNAKPFIF_01366 1e-07
KNAKPFIF_01367 5.4e-130 ykjA S Protein of unknown function (DUF421)
KNAKPFIF_01368 1e-98 ykkA S Protein of unknown function (DUF664)
KNAKPFIF_01369 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KNAKPFIF_01370 3.5e-55 ykkC P Multidrug resistance protein
KNAKPFIF_01371 2.2e-48 ykkD P Multidrug resistance protein
KNAKPFIF_01372 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KNAKPFIF_01373 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KNAKPFIF_01374 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KNAKPFIF_01375 1.3e-70 ohrA O Organic hydroperoxide resistance protein
KNAKPFIF_01376 3.9e-75 ohrR K COG1846 Transcriptional regulators
KNAKPFIF_01377 8.4e-72 ohrB O Organic hydroperoxide resistance protein
KNAKPFIF_01379 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
KNAKPFIF_01380 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KNAKPFIF_01381 1.7e-176 isp O Belongs to the peptidase S8 family
KNAKPFIF_01382 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KNAKPFIF_01383 1.8e-136 ykoC P Cobalt transport protein
KNAKPFIF_01384 4.6e-311 P ABC transporter, ATP-binding protein
KNAKPFIF_01385 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
KNAKPFIF_01386 7.9e-111 ykoF S YKOF-related Family
KNAKPFIF_01387 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_01388 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
KNAKPFIF_01389 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
KNAKPFIF_01390 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
KNAKPFIF_01393 2.2e-222 mgtE P Acts as a magnesium transporter
KNAKPFIF_01394 1.4e-53 tnrA K transcriptional
KNAKPFIF_01395 5.9e-18
KNAKPFIF_01396 6.9e-26 ykoL
KNAKPFIF_01397 1.3e-81 mhqR K transcriptional
KNAKPFIF_01398 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KNAKPFIF_01399 3.7e-99 ykoP G polysaccharide deacetylase
KNAKPFIF_01400 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KNAKPFIF_01401 0.0 ykoS
KNAKPFIF_01402 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KNAKPFIF_01403 2.3e-262 ligD 6.5.1.1 L ATP-dependent DNA ligase
KNAKPFIF_01404 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KNAKPFIF_01405 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
KNAKPFIF_01406 1.4e-116 ykoX S membrane-associated protein
KNAKPFIF_01407 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KNAKPFIF_01408 4.7e-129 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNAKPFIF_01409 8.2e-117 rsgI S Anti-sigma factor N-terminus
KNAKPFIF_01410 1.9e-26 sspD S small acid-soluble spore protein
KNAKPFIF_01411 1.5e-124 ykrK S Domain of unknown function (DUF1836)
KNAKPFIF_01412 7e-156 htpX O Belongs to the peptidase M48B family
KNAKPFIF_01413 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
KNAKPFIF_01414 1.2e-10 ydfR S Protein of unknown function (DUF421)
KNAKPFIF_01415 4.5e-22 ykzE
KNAKPFIF_01416 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KNAKPFIF_01417 0.0 kinE 2.7.13.3 T Histidine kinase
KNAKPFIF_01418 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KNAKPFIF_01420 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KNAKPFIF_01421 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KNAKPFIF_01422 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KNAKPFIF_01423 8e-232 mtnE 2.6.1.83 E Aminotransferase
KNAKPFIF_01424 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KNAKPFIF_01425 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KNAKPFIF_01426 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KNAKPFIF_01427 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KNAKPFIF_01428 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
KNAKPFIF_01429 6.4e-09 S Spo0E like sporulation regulatory protein
KNAKPFIF_01430 1.4e-64 eag
KNAKPFIF_01431 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KNAKPFIF_01432 1.3e-75 ykvE K transcriptional
KNAKPFIF_01433 2.5e-125 motB N Flagellar motor protein
KNAKPFIF_01434 2.7e-138 motA N flagellar motor
KNAKPFIF_01435 0.0 clpE O Belongs to the ClpA ClpB family
KNAKPFIF_01436 8.7e-182 ykvI S membrane
KNAKPFIF_01437 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KNAKPFIF_01438 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KNAKPFIF_01439 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KNAKPFIF_01440 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KNAKPFIF_01441 2e-61 ykvN K Transcriptional regulator
KNAKPFIF_01442 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
KNAKPFIF_01443 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
KNAKPFIF_01444 1.2e-35 3.5.1.104 M LysM domain
KNAKPFIF_01445 8.5e-133 G Glycosyl hydrolases family 18
KNAKPFIF_01446 5.6e-46 ykvR S Protein of unknown function (DUF3219)
KNAKPFIF_01447 6e-25 ykvS S protein conserved in bacteria
KNAKPFIF_01448 2.8e-28
KNAKPFIF_01449 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
KNAKPFIF_01450 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KNAKPFIF_01451 4.9e-90 stoA CO thiol-disulfide
KNAKPFIF_01452 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KNAKPFIF_01453 3.8e-09
KNAKPFIF_01454 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KNAKPFIF_01456 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
KNAKPFIF_01458 4.5e-128 glcT K antiterminator
KNAKPFIF_01459 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KNAKPFIF_01460 2.1e-39 ptsH G phosphocarrier protein HPr
KNAKPFIF_01461 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KNAKPFIF_01462 7.2e-39 splA S Transcriptional regulator
KNAKPFIF_01463 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
KNAKPFIF_01464 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNAKPFIF_01465 2e-264 mcpC NT chemotaxis protein
KNAKPFIF_01466 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KNAKPFIF_01467 8e-124 ykwD J protein with SCP PR1 domains
KNAKPFIF_01468 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KNAKPFIF_01469 0.0 pilS 2.7.13.3 T Histidine kinase
KNAKPFIF_01470 8e-224 patA 2.6.1.1 E Aminotransferase
KNAKPFIF_01471 2.2e-15
KNAKPFIF_01472 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
KNAKPFIF_01473 1.7e-84 ykyB S YkyB-like protein
KNAKPFIF_01474 1.6e-238 ykuC EGP Major facilitator Superfamily
KNAKPFIF_01475 4.6e-88 ykuD S protein conserved in bacteria
KNAKPFIF_01476 9.4e-166 ykuE S Metallophosphoesterase
KNAKPFIF_01477 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_01478 0.0 3.2.1.132 M Putative peptidoglycan binding domain
KNAKPFIF_01479 1.7e-93 M Peptidoglycan-binding domain 1 protein
KNAKPFIF_01481 5.2e-234 ykuI T Diguanylate phosphodiesterase
KNAKPFIF_01482 3.9e-37 ykuJ S protein conserved in bacteria
KNAKPFIF_01483 4.4e-94 ykuK S Ribonuclease H-like
KNAKPFIF_01484 3.9e-27 ykzF S Antirepressor AbbA
KNAKPFIF_01485 1.6e-76 ykuL S CBS domain
KNAKPFIF_01486 3.5e-168 ccpC K Transcriptional regulator
KNAKPFIF_01487 5.7e-88 fld C Flavodoxin domain
KNAKPFIF_01488 3.2e-177 ykuO
KNAKPFIF_01489 3.2e-80 fld C Flavodoxin
KNAKPFIF_01490 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KNAKPFIF_01491 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KNAKPFIF_01492 9e-37 ykuS S Belongs to the UPF0180 family
KNAKPFIF_01493 8.8e-142 ykuT M Mechanosensitive ion channel
KNAKPFIF_01494 3.9e-101 ykuU O Alkyl hydroperoxide reductase
KNAKPFIF_01495 4.4e-82 ykuV CO thiol-disulfide
KNAKPFIF_01496 5.8e-95 rok K Repressor of ComK
KNAKPFIF_01497 2.9e-147 yknT
KNAKPFIF_01498 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KNAKPFIF_01499 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KNAKPFIF_01500 8.1e-246 moeA 2.10.1.1 H molybdopterin
KNAKPFIF_01501 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KNAKPFIF_01502 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KNAKPFIF_01503 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KNAKPFIF_01504 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
KNAKPFIF_01505 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KNAKPFIF_01506 1e-117 yknW S Yip1 domain
KNAKPFIF_01507 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KNAKPFIF_01508 2.5e-124 macB V ABC transporter, ATP-binding protein
KNAKPFIF_01509 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
KNAKPFIF_01510 3.1e-136 fruR K Transcriptional regulator
KNAKPFIF_01511 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KNAKPFIF_01512 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KNAKPFIF_01513 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KNAKPFIF_01514 8.1e-39 ykoA
KNAKPFIF_01515 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KNAKPFIF_01516 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNAKPFIF_01517 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KNAKPFIF_01518 1.1e-12 S Uncharacterized protein YkpC
KNAKPFIF_01519 7.7e-183 mreB D Rod-share determining protein MreBH
KNAKPFIF_01520 1.5e-43 abrB K of stationary sporulation gene expression
KNAKPFIF_01521 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KNAKPFIF_01522 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KNAKPFIF_01523 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
KNAKPFIF_01524 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KNAKPFIF_01525 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNAKPFIF_01526 8.2e-31 ykzG S Belongs to the UPF0356 family
KNAKPFIF_01527 1.4e-147 ykrA S hydrolases of the HAD superfamily
KNAKPFIF_01528 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KNAKPFIF_01530 2e-115 recN L Putative cell-wall binding lipoprotein
KNAKPFIF_01531 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KNAKPFIF_01532 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KNAKPFIF_01533 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KNAKPFIF_01534 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KNAKPFIF_01535 6.6e-60 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KNAKPFIF_01536 3.5e-277 speA 4.1.1.19 E Arginine
KNAKPFIF_01537 1.6e-42 yktA S Belongs to the UPF0223 family
KNAKPFIF_01538 7.1e-118 yktB S Belongs to the UPF0637 family
KNAKPFIF_01539 7.1e-26 ykzI
KNAKPFIF_01540 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
KNAKPFIF_01541 6.9e-78 ykzC S Acetyltransferase (GNAT) family
KNAKPFIF_01542 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KNAKPFIF_01543 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KNAKPFIF_01544 0.0 ylaA
KNAKPFIF_01545 2.7e-42 ylaB
KNAKPFIF_01546 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_01547 1.2e-11 sigC S Putative zinc-finger
KNAKPFIF_01548 1.8e-38 ylaE
KNAKPFIF_01549 8.2e-22 S Family of unknown function (DUF5325)
KNAKPFIF_01550 0.0 typA T GTP-binding protein TypA
KNAKPFIF_01551 4.2e-47 ylaH S YlaH-like protein
KNAKPFIF_01552 2.5e-32 ylaI S protein conserved in bacteria
KNAKPFIF_01553 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KNAKPFIF_01554 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KNAKPFIF_01555 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KNAKPFIF_01556 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KNAKPFIF_01557 8.7e-44 ylaN S Belongs to the UPF0358 family
KNAKPFIF_01558 4.5e-214 ftsW D Belongs to the SEDS family
KNAKPFIF_01559 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KNAKPFIF_01560 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KNAKPFIF_01561 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KNAKPFIF_01562 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KNAKPFIF_01563 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KNAKPFIF_01564 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KNAKPFIF_01565 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KNAKPFIF_01566 3e-167 ctaG S cytochrome c oxidase
KNAKPFIF_01567 7e-62 ylbA S YugN-like family
KNAKPFIF_01568 2.6e-74 ylbB T COG0517 FOG CBS domain
KNAKPFIF_01569 3e-201 ylbC S protein with SCP PR1 domains
KNAKPFIF_01570 4.1e-63 ylbD S Putative coat protein
KNAKPFIF_01571 6.7e-37 ylbE S YlbE-like protein
KNAKPFIF_01572 1.8e-75 ylbF S Belongs to the UPF0342 family
KNAKPFIF_01573 7.5e-39 ylbG S UPF0298 protein
KNAKPFIF_01574 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
KNAKPFIF_01575 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KNAKPFIF_01576 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
KNAKPFIF_01577 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KNAKPFIF_01578 6.8e-187 ylbL T Belongs to the peptidase S16 family
KNAKPFIF_01579 2.8e-235 ylbM S Belongs to the UPF0348 family
KNAKPFIF_01581 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
KNAKPFIF_01582 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KNAKPFIF_01583 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KNAKPFIF_01584 4e-89 ylbP K n-acetyltransferase
KNAKPFIF_01585 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KNAKPFIF_01586 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KNAKPFIF_01587 2.9e-78 mraZ K Belongs to the MraZ family
KNAKPFIF_01588 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KNAKPFIF_01589 3.7e-44 ftsL D Essential cell division protein
KNAKPFIF_01590 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KNAKPFIF_01591 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KNAKPFIF_01592 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KNAKPFIF_01593 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KNAKPFIF_01594 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KNAKPFIF_01595 5.7e-186 spoVE D Belongs to the SEDS family
KNAKPFIF_01596 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KNAKPFIF_01597 5.3e-167 murB 1.3.1.98 M cell wall formation
KNAKPFIF_01598 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KNAKPFIF_01599 2.4e-103 ylxW S protein conserved in bacteria
KNAKPFIF_01600 1e-102 ylxX S protein conserved in bacteria
KNAKPFIF_01601 6.2e-58 sbp S small basic protein
KNAKPFIF_01602 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KNAKPFIF_01603 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KNAKPFIF_01604 0.0 bpr O COG1404 Subtilisin-like serine proteases
KNAKPFIF_01605 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KNAKPFIF_01606 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNAKPFIF_01607 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNAKPFIF_01608 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KNAKPFIF_01609 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
KNAKPFIF_01610 2.4e-37 ylmC S sporulation protein
KNAKPFIF_01611 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KNAKPFIF_01612 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KNAKPFIF_01613 3.3e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KNAKPFIF_01614 1.3e-39 yggT S membrane
KNAKPFIF_01615 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KNAKPFIF_01616 2.6e-67 divIVA D Cell division initiation protein
KNAKPFIF_01617 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KNAKPFIF_01618 1.3e-63 dksA T COG1734 DnaK suppressor protein
KNAKPFIF_01619 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KNAKPFIF_01620 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KNAKPFIF_01621 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KNAKPFIF_01622 9e-232 pyrP F Xanthine uracil
KNAKPFIF_01623 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KNAKPFIF_01624 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KNAKPFIF_01625 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KNAKPFIF_01626 0.0 carB 6.3.5.5 F Belongs to the CarB family
KNAKPFIF_01627 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KNAKPFIF_01628 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KNAKPFIF_01629 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KNAKPFIF_01630 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KNAKPFIF_01632 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KNAKPFIF_01633 1.1e-179 cysP P phosphate transporter
KNAKPFIF_01634 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KNAKPFIF_01635 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KNAKPFIF_01636 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KNAKPFIF_01637 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KNAKPFIF_01638 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KNAKPFIF_01639 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KNAKPFIF_01640 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KNAKPFIF_01641 2.4e-156 yloC S stress-induced protein
KNAKPFIF_01642 1.5e-40 ylzA S Belongs to the UPF0296 family
KNAKPFIF_01643 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KNAKPFIF_01644 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KNAKPFIF_01645 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KNAKPFIF_01646 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KNAKPFIF_01647 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KNAKPFIF_01648 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KNAKPFIF_01649 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KNAKPFIF_01650 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KNAKPFIF_01651 2.4e-141 stp 3.1.3.16 T phosphatase
KNAKPFIF_01652 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KNAKPFIF_01653 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KNAKPFIF_01654 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KNAKPFIF_01655 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
KNAKPFIF_01656 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KNAKPFIF_01657 5.5e-59 asp S protein conserved in bacteria
KNAKPFIF_01658 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
KNAKPFIF_01659 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KNAKPFIF_01660 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
KNAKPFIF_01661 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KNAKPFIF_01662 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KNAKPFIF_01663 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KNAKPFIF_01664 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KNAKPFIF_01665 6.1e-129 IQ reductase
KNAKPFIF_01666 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KNAKPFIF_01667 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KNAKPFIF_01668 0.0 smc D Required for chromosome condensation and partitioning
KNAKPFIF_01669 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KNAKPFIF_01670 2.9e-87
KNAKPFIF_01671 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KNAKPFIF_01672 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KNAKPFIF_01673 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KNAKPFIF_01674 4.5e-36 ylqC S Belongs to the UPF0109 family
KNAKPFIF_01675 6.3e-61 ylqD S YlqD protein
KNAKPFIF_01676 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KNAKPFIF_01677 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KNAKPFIF_01678 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KNAKPFIF_01679 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KNAKPFIF_01680 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNAKPFIF_01681 1.4e-288 ylqG
KNAKPFIF_01682 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KNAKPFIF_01683 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KNAKPFIF_01684 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KNAKPFIF_01685 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KNAKPFIF_01686 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KNAKPFIF_01687 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KNAKPFIF_01688 2.2e-168 xerC L tyrosine recombinase XerC
KNAKPFIF_01689 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KNAKPFIF_01690 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KNAKPFIF_01691 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KNAKPFIF_01692 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KNAKPFIF_01693 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
KNAKPFIF_01694 1.9e-31 fliE N Flagellar hook-basal body
KNAKPFIF_01695 2.4e-255 fliF N The M ring may be actively involved in energy transduction
KNAKPFIF_01696 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KNAKPFIF_01697 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KNAKPFIF_01698 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KNAKPFIF_01699 1.5e-69 fliJ N Flagellar biosynthesis chaperone
KNAKPFIF_01700 7.7e-37 ylxF S MgtE intracellular N domain
KNAKPFIF_01701 1.2e-221 fliK N Flagellar hook-length control protein
KNAKPFIF_01702 1.7e-72 flgD N Flagellar basal body rod modification protein
KNAKPFIF_01703 8.2e-140 flgG N Flagellar basal body rod
KNAKPFIF_01704 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
KNAKPFIF_01705 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KNAKPFIF_01706 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KNAKPFIF_01707 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KNAKPFIF_01708 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
KNAKPFIF_01709 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KNAKPFIF_01710 2.2e-36 fliQ N Role in flagellar biosynthesis
KNAKPFIF_01711 3.6e-132 fliR N Flagellar biosynthetic protein FliR
KNAKPFIF_01712 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KNAKPFIF_01713 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KNAKPFIF_01714 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
KNAKPFIF_01715 7.5e-158 flhG D Belongs to the ParA family
KNAKPFIF_01716 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KNAKPFIF_01717 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KNAKPFIF_01718 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KNAKPFIF_01719 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KNAKPFIF_01720 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KNAKPFIF_01721 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNAKPFIF_01722 4.3e-78 ylxL
KNAKPFIF_01723 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KNAKPFIF_01724 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KNAKPFIF_01725 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KNAKPFIF_01726 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KNAKPFIF_01727 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KNAKPFIF_01728 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KNAKPFIF_01729 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KNAKPFIF_01730 7.7e-233 rasP M zinc metalloprotease
KNAKPFIF_01731 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KNAKPFIF_01732 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KNAKPFIF_01733 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
KNAKPFIF_01734 7.3e-203 nusA K Participates in both transcription termination and antitermination
KNAKPFIF_01735 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
KNAKPFIF_01736 3.1e-47 ylxQ J ribosomal protein
KNAKPFIF_01737 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KNAKPFIF_01738 3e-44 ylxP S protein conserved in bacteria
KNAKPFIF_01739 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KNAKPFIF_01740 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KNAKPFIF_01741 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KNAKPFIF_01742 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KNAKPFIF_01743 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KNAKPFIF_01744 3.2e-172 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KNAKPFIF_01745 4.4e-233 pepR S Belongs to the peptidase M16 family
KNAKPFIF_01746 2.6e-42 ymxH S YlmC YmxH family
KNAKPFIF_01747 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KNAKPFIF_01748 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KNAKPFIF_01749 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KNAKPFIF_01750 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KNAKPFIF_01751 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KNAKPFIF_01752 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KNAKPFIF_01753 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KNAKPFIF_01754 4.4e-32 S YlzJ-like protein
KNAKPFIF_01755 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KNAKPFIF_01756 1.4e-133 ymfC K Transcriptional regulator
KNAKPFIF_01757 1.1e-204 ymfD EGP Major facilitator Superfamily
KNAKPFIF_01758 1.2e-233 ymfF S Peptidase M16
KNAKPFIF_01759 1.4e-242 ymfH S zinc protease
KNAKPFIF_01760 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KNAKPFIF_01761 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
KNAKPFIF_01762 2.4e-76 ymfK S Protein of unknown function (DUF3388)
KNAKPFIF_01763 3.1e-53 ymfK S Protein of unknown function (DUF3388)
KNAKPFIF_01764 1.9e-124 ymfM S protein conserved in bacteria
KNAKPFIF_01765 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KNAKPFIF_01766 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
KNAKPFIF_01767 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KNAKPFIF_01768 1e-215 pbpX V Beta-lactamase
KNAKPFIF_01769 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
KNAKPFIF_01770 1.9e-152 ymdB S protein conserved in bacteria
KNAKPFIF_01771 1.2e-36 spoVS S Stage V sporulation protein S
KNAKPFIF_01772 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KNAKPFIF_01773 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KNAKPFIF_01774 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KNAKPFIF_01775 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KNAKPFIF_01776 2.2e-88 cotE S Spore coat protein
KNAKPFIF_01777 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KNAKPFIF_01778 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KNAKPFIF_01779 2.3e-70 S Regulatory protein YrvL
KNAKPFIF_01781 1.2e-97 ymcC S Membrane
KNAKPFIF_01782 4.4e-109 pksA K Transcriptional regulator
KNAKPFIF_01783 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
KNAKPFIF_01784 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KNAKPFIF_01786 2.4e-186 pksD Q Acyl transferase domain
KNAKPFIF_01787 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KNAKPFIF_01788 1.4e-37 acpK IQ Phosphopantetheine attachment site
KNAKPFIF_01789 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KNAKPFIF_01790 1.3e-245 pksG 2.3.3.10 I synthase
KNAKPFIF_01791 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
KNAKPFIF_01792 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KNAKPFIF_01793 0.0 rhiB IQ polyketide synthase
KNAKPFIF_01794 0.0 pfaA Q Polyketide synthase of type I
KNAKPFIF_01795 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
KNAKPFIF_01796 0.0 dhbF IQ polyketide synthase
KNAKPFIF_01797 0.0 dhbF IQ polyketide synthase
KNAKPFIF_01798 0.0 pks13 HQ Beta-ketoacyl synthase
KNAKPFIF_01799 2.5e-233 cypA C Cytochrome P450
KNAKPFIF_01800 1.2e-61 ymzB
KNAKPFIF_01801 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
KNAKPFIF_01802 4.6e-252 aprX O Belongs to the peptidase S8 family
KNAKPFIF_01803 2.1e-126 ymaC S Replication protein
KNAKPFIF_01804 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
KNAKPFIF_01805 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
KNAKPFIF_01806 4.9e-51 ebrA P Small Multidrug Resistance protein
KNAKPFIF_01808 2.1e-46 ymaF S YmaF family
KNAKPFIF_01809 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KNAKPFIF_01810 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KNAKPFIF_01811 6.3e-23
KNAKPFIF_01812 4.5e-22 ymzA
KNAKPFIF_01813 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KNAKPFIF_01814 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNAKPFIF_01815 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNAKPFIF_01816 2e-109 ymaB
KNAKPFIF_01817 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KNAKPFIF_01818 1.7e-176 spoVK O stage V sporulation protein K
KNAKPFIF_01819 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KNAKPFIF_01820 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KNAKPFIF_01821 1.1e-68 glnR K transcriptional
KNAKPFIF_01822 7e-261 glnA 6.3.1.2 E glutamine synthetase
KNAKPFIF_01823 5e-10
KNAKPFIF_01824 2.5e-32
KNAKPFIF_01825 5.8e-39
KNAKPFIF_01826 6.8e-80 G regulation of fungal-type cell wall biogenesis
KNAKPFIF_01827 4.9e-145 ynaC
KNAKPFIF_01828 2e-99 ynaD J Acetyltransferase (GNAT) domain
KNAKPFIF_01829 1.9e-123 ynaE S Domain of unknown function (DUF3885)
KNAKPFIF_01830 6.4e-60 ynaF
KNAKPFIF_01833 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
KNAKPFIF_01834 2.7e-255 xynT G MFS/sugar transport protein
KNAKPFIF_01835 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KNAKPFIF_01836 1e-215 xylR GK ROK family
KNAKPFIF_01837 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KNAKPFIF_01838 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KNAKPFIF_01839 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
KNAKPFIF_01840 3.5e-247 iolT EGP Major facilitator Superfamily
KNAKPFIF_01841 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KNAKPFIF_01842 6.3e-84 yncE S Protein of unknown function (DUF2691)
KNAKPFIF_01843 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KNAKPFIF_01844 5.2e-15
KNAKPFIF_01847 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KNAKPFIF_01849 1.3e-134 S Domain of unknown function, YrpD
KNAKPFIF_01852 7.9e-25 tatA U protein secretion
KNAKPFIF_01853 1.8e-71
KNAKPFIF_01854 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KNAKPFIF_01857 5.7e-286 gerAA EG Spore germination protein
KNAKPFIF_01858 4.5e-197 gerAB U Spore germination
KNAKPFIF_01859 4.2e-220 gerLC S Spore germination protein
KNAKPFIF_01860 7.7e-154 yndG S DoxX-like family
KNAKPFIF_01861 2.6e-117 yndH S Domain of unknown function (DUF4166)
KNAKPFIF_01862 0.0 yndJ S YndJ-like protein
KNAKPFIF_01864 8.6e-139 yndL S Replication protein
KNAKPFIF_01865 5.8e-74 yndM S Protein of unknown function (DUF2512)
KNAKPFIF_01866 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KNAKPFIF_01868 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KNAKPFIF_01869 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KNAKPFIF_01870 9.2e-113 yneB L resolvase
KNAKPFIF_01871 1.3e-32 ynzC S UPF0291 protein
KNAKPFIF_01872 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KNAKPFIF_01873 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
KNAKPFIF_01874 1.8e-28 yneF S UPF0154 protein
KNAKPFIF_01875 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
KNAKPFIF_01876 7.1e-127 ccdA O cytochrome c biogenesis protein
KNAKPFIF_01877 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KNAKPFIF_01878 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KNAKPFIF_01879 4.2e-74 yneK S Protein of unknown function (DUF2621)
KNAKPFIF_01880 4.1e-65 hspX O Spore coat protein
KNAKPFIF_01881 3.9e-19 sspP S Belongs to the SspP family
KNAKPFIF_01882 2.2e-14 sspO S Belongs to the SspO family
KNAKPFIF_01883 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KNAKPFIF_01884 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KNAKPFIF_01886 3.1e-08 sspN S Small acid-soluble spore protein N family
KNAKPFIF_01887 3.9e-35 tlp S Belongs to the Tlp family
KNAKPFIF_01888 1.2e-73 yneP S Thioesterase-like superfamily
KNAKPFIF_01889 1.3e-53 yneQ
KNAKPFIF_01890 4.1e-49 yneR S Belongs to the HesB IscA family
KNAKPFIF_01891 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KNAKPFIF_01892 6.6e-69 yccU S CoA-binding protein
KNAKPFIF_01893 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNAKPFIF_01894 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KNAKPFIF_01895 5.9e-43 ynfC
KNAKPFIF_01896 8.2e-252 agcS E Sodium alanine symporter
KNAKPFIF_01897 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KNAKPFIF_01899 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KNAKPFIF_01900 6.4e-243 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KNAKPFIF_01901 1.7e-28 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KNAKPFIF_01902 2e-79 yngA S membrane
KNAKPFIF_01903 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KNAKPFIF_01904 5.5e-104 yngC S membrane-associated protein
KNAKPFIF_01905 1.1e-231 nrnB S phosphohydrolase (DHH superfamily)
KNAKPFIF_01906 1.3e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KNAKPFIF_01907 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KNAKPFIF_01908 2.2e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KNAKPFIF_01909 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KNAKPFIF_01910 8.1e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KNAKPFIF_01911 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KNAKPFIF_01912 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KNAKPFIF_01913 5.5e-302 yngK T Glycosyl hydrolase-like 10
KNAKPFIF_01914 3.1e-63 yngL S Protein of unknown function (DUF1360)
KNAKPFIF_01915 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KNAKPFIF_01916 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_01917 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_01918 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_01919 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_01920 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KNAKPFIF_01921 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
KNAKPFIF_01922 2.3e-246 yoeA V MATE efflux family protein
KNAKPFIF_01923 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
KNAKPFIF_01925 2.2e-96 L Integrase
KNAKPFIF_01926 3e-34 yoeD G Helix-turn-helix domain
KNAKPFIF_01927 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KNAKPFIF_01928 2.5e-158 gltR1 K Transcriptional regulator
KNAKPFIF_01929 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KNAKPFIF_01930 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KNAKPFIF_01931 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KNAKPFIF_01932 7.8e-155 gltC K Transcriptional regulator
KNAKPFIF_01933 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KNAKPFIF_01934 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNAKPFIF_01935 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KNAKPFIF_01936 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_01937 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
KNAKPFIF_01938 3.1e-144 yoxB
KNAKPFIF_01939 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KNAKPFIF_01940 6.2e-235 yoaB EGP Major facilitator Superfamily
KNAKPFIF_01941 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KNAKPFIF_01942 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNAKPFIF_01943 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KNAKPFIF_01944 1.9e-33 yoaF
KNAKPFIF_01945 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
KNAKPFIF_01946 7e-14
KNAKPFIF_01947 1.5e-38 S Protein of unknown function (DUF4025)
KNAKPFIF_01948 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
KNAKPFIF_01949 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KNAKPFIF_01950 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
KNAKPFIF_01951 2.3e-111 yoaK S Membrane
KNAKPFIF_01952 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KNAKPFIF_01953 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
KNAKPFIF_01955 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
KNAKPFIF_01957 1.5e-146 yoaP 3.1.3.18 K YoaP-like
KNAKPFIF_01958 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
KNAKPFIF_01959 4.1e-89
KNAKPFIF_01960 2.4e-172 yoaR V vancomycin resistance protein
KNAKPFIF_01961 4.3e-75 yoaS S Protein of unknown function (DUF2975)
KNAKPFIF_01962 4.2e-37 yozG K Transcriptional regulator
KNAKPFIF_01963 1.1e-149 yoaT S Protein of unknown function (DUF817)
KNAKPFIF_01964 8.6e-159 yoaU K LysR substrate binding domain
KNAKPFIF_01965 6e-160 yijE EG EamA-like transporter family
KNAKPFIF_01966 3.7e-78 yoaW
KNAKPFIF_01967 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KNAKPFIF_01968 2.3e-170 bla 3.5.2.6 V beta-lactamase
KNAKPFIF_01972 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KNAKPFIF_01973 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KNAKPFIF_01974 1.4e-37 S TM2 domain
KNAKPFIF_01975 5.7e-58 K Helix-turn-helix
KNAKPFIF_01977 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
KNAKPFIF_01978 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
KNAKPFIF_01979 1.8e-178 yobF
KNAKPFIF_01984 1.7e-207 S aspartate phosphatase
KNAKPFIF_01986 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNAKPFIF_01987 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNAKPFIF_01988 2.6e-38 S YolD-like protein
KNAKPFIF_01989 1.2e-49
KNAKPFIF_01990 0.0 K Psort location Cytoplasmic, score
KNAKPFIF_01991 2.7e-157 yobJ
KNAKPFIF_01992 3e-86 S SMI1-KNR4 cell-wall
KNAKPFIF_01993 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KNAKPFIF_01994 7.9e-105 yokH G SMI1 / KNR4 family
KNAKPFIF_01995 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
KNAKPFIF_01996 0.0 yobO M Pectate lyase superfamily protein
KNAKPFIF_01997 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KNAKPFIF_01998 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
KNAKPFIF_01999 2.5e-143 yobR 2.3.1.1 J FR47-like protein
KNAKPFIF_02000 3e-99 yobS K Transcriptional regulator
KNAKPFIF_02001 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KNAKPFIF_02002 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
KNAKPFIF_02003 9e-178 yobV K WYL domain
KNAKPFIF_02004 2.5e-95 yobW
KNAKPFIF_02005 1e-51 czrA K transcriptional
KNAKPFIF_02006 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KNAKPFIF_02007 1.5e-92 yozB S membrane
KNAKPFIF_02008 2.2e-145
KNAKPFIF_02009 1.9e-94 yocC
KNAKPFIF_02010 6.9e-189 yocD 3.4.17.13 V peptidase S66
KNAKPFIF_02011 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KNAKPFIF_02012 3.2e-198 desK 2.7.13.3 T Histidine kinase
KNAKPFIF_02013 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNAKPFIF_02014 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
KNAKPFIF_02015 0.0 recQ 3.6.4.12 L DNA helicase
KNAKPFIF_02016 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KNAKPFIF_02017 3.3e-83 dksA T general stress protein
KNAKPFIF_02018 6.4e-54 yocL
KNAKPFIF_02019 6.6e-34
KNAKPFIF_02020 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
KNAKPFIF_02021 1.1e-40 yozN
KNAKPFIF_02022 1.9e-36 yocN
KNAKPFIF_02023 4.2e-56 yozO S Bacterial PH domain
KNAKPFIF_02024 2.7e-31 yozC
KNAKPFIF_02025 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KNAKPFIF_02026 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KNAKPFIF_02027 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
KNAKPFIF_02028 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KNAKPFIF_02029 5.1e-168 yocS S -transporter
KNAKPFIF_02030 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KNAKPFIF_02031 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KNAKPFIF_02032 0.0 yojO P Von Willebrand factor
KNAKPFIF_02033 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
KNAKPFIF_02034 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KNAKPFIF_02035 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KNAKPFIF_02036 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KNAKPFIF_02037 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KNAKPFIF_02039 4.2e-245 norM V Multidrug efflux pump
KNAKPFIF_02040 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KNAKPFIF_02041 2.1e-125 yojG S deacetylase
KNAKPFIF_02042 2.2e-60 yojF S Protein of unknown function (DUF1806)
KNAKPFIF_02043 1.5e-43
KNAKPFIF_02044 3.5e-163 rarD S -transporter
KNAKPFIF_02045 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
KNAKPFIF_02046 3.4e-09
KNAKPFIF_02047 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
KNAKPFIF_02048 3.8e-66 yodA S tautomerase
KNAKPFIF_02049 1.7e-57 yodB K transcriptional
KNAKPFIF_02050 4.8e-108 yodC C nitroreductase
KNAKPFIF_02051 3.8e-113 mhqD S Carboxylesterase
KNAKPFIF_02052 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
KNAKPFIF_02053 6.2e-28 S Protein of unknown function (DUF3311)
KNAKPFIF_02054 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNAKPFIF_02055 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KNAKPFIF_02056 1.7e-128 yodH Q Methyltransferase
KNAKPFIF_02057 5.2e-24 yodI
KNAKPFIF_02058 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KNAKPFIF_02059 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KNAKPFIF_02060 5.3e-09
KNAKPFIF_02061 3.6e-54 yodL S YodL-like
KNAKPFIF_02062 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
KNAKPFIF_02063 2.8e-24 yozD S YozD-like protein
KNAKPFIF_02065 1.4e-124 yodN
KNAKPFIF_02066 1.4e-36 yozE S Belongs to the UPF0346 family
KNAKPFIF_02067 2.9e-47 yokU S YokU-like protein, putative antitoxin
KNAKPFIF_02068 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
KNAKPFIF_02069 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KNAKPFIF_02070 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
KNAKPFIF_02071 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KNAKPFIF_02072 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KNAKPFIF_02073 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KNAKPFIF_02076 2.9e-145 yiiD K acetyltransferase
KNAKPFIF_02077 1e-256 cgeD M maturation of the outermost layer of the spore
KNAKPFIF_02078 3.5e-38 cgeC
KNAKPFIF_02079 1.2e-65 cgeA
KNAKPFIF_02080 3.3e-188 cgeB S Spore maturation protein
KNAKPFIF_02081 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KNAKPFIF_02082 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
KNAKPFIF_02084 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KNAKPFIF_02085 1.4e-10 K Cro/C1-type HTH DNA-binding domain
KNAKPFIF_02093 1.9e-168 S Calcineurin-like phosphoesterase
KNAKPFIF_02094 2.5e-30 sspB S spore protein
KNAKPFIF_02099 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
KNAKPFIF_02100 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KNAKPFIF_02101 6.1e-38 O Glutaredoxin
KNAKPFIF_02102 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNAKPFIF_02103 3.3e-97 L HNH endonuclease
KNAKPFIF_02104 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNAKPFIF_02105 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNAKPFIF_02106 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KNAKPFIF_02107 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KNAKPFIF_02124 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KNAKPFIF_02126 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KNAKPFIF_02127 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
KNAKPFIF_02132 9.9e-115 DR0488 S protein conserved in bacteria
KNAKPFIF_02133 0.0 2.7.7.7 L DNA polymerase
KNAKPFIF_02134 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KNAKPFIF_02135 1.2e-224 L DNA primase activity
KNAKPFIF_02136 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
KNAKPFIF_02137 1.4e-86
KNAKPFIF_02138 7.6e-180 L AAA domain
KNAKPFIF_02139 1.3e-170
KNAKPFIF_02144 0.0 M Parallel beta-helix repeats
KNAKPFIF_02145 7.7e-149 S Pfam:DUF867
KNAKPFIF_02148 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
KNAKPFIF_02149 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
KNAKPFIF_02150 2.3e-77
KNAKPFIF_02157 1e-44
KNAKPFIF_02159 1.5e-97 S Protein of unknown function (DUF1273)
KNAKPFIF_02161 3e-78 yoqH M LysM domain
KNAKPFIF_02164 8.8e-12 S Protein of unknown function (DUF2815)
KNAKPFIF_02165 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
KNAKPFIF_02176 1.1e-33 K Transcriptional regulator
KNAKPFIF_02177 2.1e-177
KNAKPFIF_02178 6e-263 S DNA-sulfur modification-associated
KNAKPFIF_02179 6.8e-198 L Belongs to the 'phage' integrase family
KNAKPFIF_02184 6.6e-106
KNAKPFIF_02186 1.2e-86
KNAKPFIF_02187 1.1e-96 S Super-infection exclusion protein B
KNAKPFIF_02192 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
KNAKPFIF_02193 3.8e-259
KNAKPFIF_02194 4.6e-35 K Cro/C1-type HTH DNA-binding domain
KNAKPFIF_02195 1.4e-256
KNAKPFIF_02197 5.9e-238
KNAKPFIF_02199 4e-17
KNAKPFIF_02200 5.7e-55 bldD K domain, Protein
KNAKPFIF_02203 0.0
KNAKPFIF_02204 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KNAKPFIF_02206 2.6e-230
KNAKPFIF_02209 1.8e-175
KNAKPFIF_02210 0.0 gp17a S Terminase-like family
KNAKPFIF_02211 6.3e-282
KNAKPFIF_02212 2.1e-266
KNAKPFIF_02213 1.6e-94
KNAKPFIF_02214 5.7e-186
KNAKPFIF_02215 5.1e-81
KNAKPFIF_02216 1.1e-68
KNAKPFIF_02218 1.4e-121
KNAKPFIF_02219 2.6e-91
KNAKPFIF_02220 8.1e-131
KNAKPFIF_02221 1.6e-90
KNAKPFIF_02224 1e-57
KNAKPFIF_02225 1.1e-172
KNAKPFIF_02226 8.1e-07
KNAKPFIF_02227 2.5e-10 xkdX
KNAKPFIF_02228 2.5e-86
KNAKPFIF_02229 6.3e-70
KNAKPFIF_02230 2.1e-193 xerH A Belongs to the 'phage' integrase family
KNAKPFIF_02235 9.3e-116
KNAKPFIF_02236 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KNAKPFIF_02237 6.2e-145 S Phage tail protein
KNAKPFIF_02238 0.0 S Pfam Transposase IS66
KNAKPFIF_02239 6.4e-115
KNAKPFIF_02240 0.0 G Exopolysaccharide biosynthesis protein
KNAKPFIF_02241 6.5e-164
KNAKPFIF_02243 1.6e-186 3.5.1.28 M Ami_2
KNAKPFIF_02244 4.4e-32 bhlA S BhlA holin family
KNAKPFIF_02245 5.5e-40 S SPP1 phage holin
KNAKPFIF_02246 3.4e-74 O protein disulfide oxidoreductase activity
KNAKPFIF_02247 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KNAKPFIF_02248 1.2e-70 CO cell redox homeostasis
KNAKPFIF_02249 0.0 V Peptidase C39 family
KNAKPFIF_02252 1.9e-239 S impB/mucB/samB family C-terminal domain
KNAKPFIF_02253 5.8e-55 S YolD-like protein
KNAKPFIF_02254 1.3e-37
KNAKPFIF_02256 6.8e-09 S Domain of unknown function (DUF4879)
KNAKPFIF_02258 2.8e-99 J Acetyltransferase (GNAT) domain
KNAKPFIF_02259 3.2e-109 yokK S SMI1 / KNR4 family
KNAKPFIF_02260 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
KNAKPFIF_02261 1.2e-302 UW nuclease activity
KNAKPFIF_02262 6.7e-92 yokH G SMI1 / KNR4 family
KNAKPFIF_02263 4.1e-203
KNAKPFIF_02264 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
KNAKPFIF_02265 1.1e-83 S Bacterial PH domain
KNAKPFIF_02266 8.4e-156 aacC 2.3.1.81 V aminoglycoside
KNAKPFIF_02269 8.9e-95
KNAKPFIF_02270 1.6e-107
KNAKPFIF_02271 2.7e-307 yokA L Recombinase
KNAKPFIF_02272 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
KNAKPFIF_02273 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KNAKPFIF_02274 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KNAKPFIF_02275 1.6e-70 ypoP K transcriptional
KNAKPFIF_02276 2.6e-223 mepA V MATE efflux family protein
KNAKPFIF_02277 5.5e-29 ypmT S Uncharacterized ympT
KNAKPFIF_02278 5e-99 ypmS S protein conserved in bacteria
KNAKPFIF_02279 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
KNAKPFIF_02280 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KNAKPFIF_02281 3.1e-40 ypmP S Protein of unknown function (DUF2535)
KNAKPFIF_02282 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KNAKPFIF_02283 1.6e-185 pspF K Transcriptional regulator
KNAKPFIF_02284 4.2e-110 hlyIII S protein, Hemolysin III
KNAKPFIF_02285 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KNAKPFIF_02286 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KNAKPFIF_02287 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KNAKPFIF_02288 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KNAKPFIF_02289 7.8e-114 ypjP S YpjP-like protein
KNAKPFIF_02290 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KNAKPFIF_02291 1.7e-75 yphP S Belongs to the UPF0403 family
KNAKPFIF_02292 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KNAKPFIF_02293 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
KNAKPFIF_02294 3.1e-110 ypgQ S phosphohydrolase
KNAKPFIF_02295 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KNAKPFIF_02296 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KNAKPFIF_02297 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KNAKPFIF_02298 7.9e-31 cspD K Cold-shock protein
KNAKPFIF_02299 3.8e-16 degR
KNAKPFIF_02300 8.1e-31 S Protein of unknown function (DUF2564)
KNAKPFIF_02301 3e-29 ypeQ S Zinc-finger
KNAKPFIF_02302 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KNAKPFIF_02303 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KNAKPFIF_02304 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
KNAKPFIF_02306 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
KNAKPFIF_02307 2e-07
KNAKPFIF_02308 1e-38 ypbS S Protein of unknown function (DUF2533)
KNAKPFIF_02309 0.0 ypbR S Dynamin family
KNAKPFIF_02310 5.1e-87 ypbQ S protein conserved in bacteria
KNAKPFIF_02311 4.4e-208 bcsA Q Naringenin-chalcone synthase
KNAKPFIF_02312 1.6e-228 pbuX F xanthine
KNAKPFIF_02313 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KNAKPFIF_02314 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KNAKPFIF_02315 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KNAKPFIF_02316 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KNAKPFIF_02317 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KNAKPFIF_02318 3.9e-187 ptxS K transcriptional
KNAKPFIF_02319 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KNAKPFIF_02320 5.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_02321 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KNAKPFIF_02323 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KNAKPFIF_02324 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KNAKPFIF_02325 3.3e-92 ypsA S Belongs to the UPF0398 family
KNAKPFIF_02326 1.3e-237 yprB L RNase_H superfamily
KNAKPFIF_02327 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KNAKPFIF_02328 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KNAKPFIF_02329 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
KNAKPFIF_02330 1.2e-48 yppG S YppG-like protein
KNAKPFIF_02332 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
KNAKPFIF_02335 2.6e-188 yppC S Protein of unknown function (DUF2515)
KNAKPFIF_02336 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KNAKPFIF_02337 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
KNAKPFIF_02338 4.7e-93 ypoC
KNAKPFIF_02339 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KNAKPFIF_02340 5.7e-129 dnaD L DNA replication protein DnaD
KNAKPFIF_02341 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KNAKPFIF_02342 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KNAKPFIF_02343 3.4e-80 ypmB S protein conserved in bacteria
KNAKPFIF_02344 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KNAKPFIF_02345 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KNAKPFIF_02346 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KNAKPFIF_02347 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KNAKPFIF_02348 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KNAKPFIF_02349 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KNAKPFIF_02350 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KNAKPFIF_02351 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KNAKPFIF_02352 6.9e-130 bshB1 S proteins, LmbE homologs
KNAKPFIF_02353 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KNAKPFIF_02354 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KNAKPFIF_02355 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KNAKPFIF_02356 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KNAKPFIF_02357 6.1e-143 ypjB S sporulation protein
KNAKPFIF_02358 4.4e-98 ypjA S membrane
KNAKPFIF_02359 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KNAKPFIF_02360 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KNAKPFIF_02361 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KNAKPFIF_02362 8.5e-78 ypiF S Protein of unknown function (DUF2487)
KNAKPFIF_02363 2.8e-99 ypiB S Belongs to the UPF0302 family
KNAKPFIF_02364 4.1e-234 S COG0457 FOG TPR repeat
KNAKPFIF_02365 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KNAKPFIF_02366 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KNAKPFIF_02367 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KNAKPFIF_02368 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KNAKPFIF_02369 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KNAKPFIF_02370 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KNAKPFIF_02371 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KNAKPFIF_02372 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KNAKPFIF_02373 3.4e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KNAKPFIF_02374 4.6e-64 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KNAKPFIF_02375 1.7e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KNAKPFIF_02376 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KNAKPFIF_02377 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KNAKPFIF_02378 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KNAKPFIF_02379 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KNAKPFIF_02380 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KNAKPFIF_02381 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KNAKPFIF_02382 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KNAKPFIF_02383 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
KNAKPFIF_02384 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KNAKPFIF_02385 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KNAKPFIF_02386 5.4e-138 yphF
KNAKPFIF_02387 1.6e-18 yphE S Protein of unknown function (DUF2768)
KNAKPFIF_02388 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KNAKPFIF_02389 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KNAKPFIF_02390 1.6e-28 ypzH
KNAKPFIF_02391 2.5e-161 seaA S YIEGIA protein
KNAKPFIF_02392 1.3e-102 yphA
KNAKPFIF_02393 1e-07 S YpzI-like protein
KNAKPFIF_02394 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KNAKPFIF_02395 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
KNAKPFIF_02396 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KNAKPFIF_02397 1.8e-23 S Family of unknown function (DUF5359)
KNAKPFIF_02398 9.2e-113 ypfA M Flagellar protein YcgR
KNAKPFIF_02399 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KNAKPFIF_02400 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KNAKPFIF_02401 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
KNAKPFIF_02402 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KNAKPFIF_02403 7.3e-247 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KNAKPFIF_02404 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KNAKPFIF_02405 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
KNAKPFIF_02406 2.8e-81 ypbF S Protein of unknown function (DUF2663)
KNAKPFIF_02407 4.6e-81 ypbE M Lysin motif
KNAKPFIF_02408 2.2e-100 ypbD S metal-dependent membrane protease
KNAKPFIF_02409 3.2e-286 recQ 3.6.4.12 L DNA helicase
KNAKPFIF_02410 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
KNAKPFIF_02411 4.7e-41 fer C Ferredoxin
KNAKPFIF_02412 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KNAKPFIF_02413 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNAKPFIF_02414 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KNAKPFIF_02415 6.8e-201 rsiX
KNAKPFIF_02416 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_02417 0.0 resE 2.7.13.3 T Histidine kinase
KNAKPFIF_02418 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_02419 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KNAKPFIF_02420 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KNAKPFIF_02421 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KNAKPFIF_02422 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KNAKPFIF_02423 1.9e-87 spmB S Spore maturation protein
KNAKPFIF_02424 3.5e-103 spmA S Spore maturation protein
KNAKPFIF_02425 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KNAKPFIF_02426 4e-98 ypuI S Protein of unknown function (DUF3907)
KNAKPFIF_02427 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KNAKPFIF_02428 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KNAKPFIF_02429 4.5e-94 ypuF S Domain of unknown function (DUF309)
KNAKPFIF_02430 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNAKPFIF_02431 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KNAKPFIF_02432 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KNAKPFIF_02433 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
KNAKPFIF_02434 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KNAKPFIF_02435 6e-55 ypuD
KNAKPFIF_02436 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KNAKPFIF_02437 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KNAKPFIF_02438 1.5e-17 S SNARE associated Golgi protein
KNAKPFIF_02441 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KNAKPFIF_02442 1.3e-149 ypuA S Secreted protein
KNAKPFIF_02443 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KNAKPFIF_02444 1.4e-273 spoVAF EG Stage V sporulation protein AF
KNAKPFIF_02445 1.4e-110 spoVAEA S stage V sporulation protein
KNAKPFIF_02446 2.2e-57 spoVAEB S stage V sporulation protein
KNAKPFIF_02447 9e-192 spoVAD I Stage V sporulation protein AD
KNAKPFIF_02448 2.3e-78 spoVAC S stage V sporulation protein AC
KNAKPFIF_02449 1e-67 spoVAB S Stage V sporulation protein AB
KNAKPFIF_02450 7.4e-112 spoVAA S Stage V sporulation protein AA
KNAKPFIF_02451 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNAKPFIF_02452 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KNAKPFIF_02453 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KNAKPFIF_02454 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KNAKPFIF_02455 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KNAKPFIF_02456 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KNAKPFIF_02457 2.6e-166 xerD L recombinase XerD
KNAKPFIF_02458 3.7e-37 S Protein of unknown function (DUF4227)
KNAKPFIF_02459 2.4e-80 fur P Belongs to the Fur family
KNAKPFIF_02460 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KNAKPFIF_02461 2e-32 yqkK
KNAKPFIF_02462 5.5e-242 mleA 1.1.1.38 C malic enzyme
KNAKPFIF_02463 3.1e-235 mleN C Na H antiporter
KNAKPFIF_02464 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KNAKPFIF_02465 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
KNAKPFIF_02466 4.5e-58 ansR K Transcriptional regulator
KNAKPFIF_02467 3e-223 yqxK 3.6.4.12 L DNA helicase
KNAKPFIF_02468 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KNAKPFIF_02470 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KNAKPFIF_02471 4e-14 yqkE S Protein of unknown function (DUF3886)
KNAKPFIF_02472 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KNAKPFIF_02473 9.4e-39 yqkC S Protein of unknown function (DUF2552)
KNAKPFIF_02474 2.8e-54 yqkB S Belongs to the HesB IscA family
KNAKPFIF_02475 4.7e-196 yqkA K GrpB protein
KNAKPFIF_02476 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KNAKPFIF_02477 3.6e-87 yqjY K acetyltransferase
KNAKPFIF_02478 2.2e-49 S YolD-like protein
KNAKPFIF_02479 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNAKPFIF_02481 5.2e-226 yqjV G Major Facilitator Superfamily
KNAKPFIF_02483 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNAKPFIF_02484 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
KNAKPFIF_02485 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KNAKPFIF_02486 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_02487 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KNAKPFIF_02488 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNAKPFIF_02489 0.0 rocB E arginine degradation protein
KNAKPFIF_02490 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KNAKPFIF_02491 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KNAKPFIF_02492 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KNAKPFIF_02493 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KNAKPFIF_02494 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KNAKPFIF_02495 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KNAKPFIF_02496 4.5e-24 yqzJ
KNAKPFIF_02497 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNAKPFIF_02498 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
KNAKPFIF_02499 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KNAKPFIF_02500 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KNAKPFIF_02501 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KNAKPFIF_02503 1.4e-98 yqjB S protein conserved in bacteria
KNAKPFIF_02504 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
KNAKPFIF_02505 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KNAKPFIF_02506 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
KNAKPFIF_02507 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
KNAKPFIF_02508 9.3e-77 yqiW S Belongs to the UPF0403 family
KNAKPFIF_02509 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KNAKPFIF_02510 7.9e-208 norA EGP Major facilitator Superfamily
KNAKPFIF_02511 2.6e-152 bmrR K helix_turn_helix, mercury resistance
KNAKPFIF_02512 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KNAKPFIF_02513 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KNAKPFIF_02514 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KNAKPFIF_02515 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KNAKPFIF_02516 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
KNAKPFIF_02517 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KNAKPFIF_02518 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KNAKPFIF_02519 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KNAKPFIF_02520 4e-34 yqzF S Protein of unknown function (DUF2627)
KNAKPFIF_02521 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KNAKPFIF_02522 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KNAKPFIF_02523 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KNAKPFIF_02524 1.8e-212 mmgC I acyl-CoA dehydrogenase
KNAKPFIF_02525 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
KNAKPFIF_02526 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
KNAKPFIF_02527 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KNAKPFIF_02528 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KNAKPFIF_02529 5.9e-27
KNAKPFIF_02530 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KNAKPFIF_02532 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KNAKPFIF_02533 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
KNAKPFIF_02534 0.0 recN L May be involved in recombinational repair of damaged DNA
KNAKPFIF_02535 1.7e-78 argR K Regulates arginine biosynthesis genes
KNAKPFIF_02536 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KNAKPFIF_02537 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KNAKPFIF_02538 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KNAKPFIF_02539 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNAKPFIF_02540 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KNAKPFIF_02541 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KNAKPFIF_02542 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KNAKPFIF_02543 2.1e-67 yqhY S protein conserved in bacteria
KNAKPFIF_02544 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KNAKPFIF_02545 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KNAKPFIF_02546 9.9e-91 spoIIIAH S SpoIIIAH-like protein
KNAKPFIF_02547 6.9e-103 spoIIIAG S stage III sporulation protein AG
KNAKPFIF_02548 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KNAKPFIF_02549 1.3e-197 spoIIIAE S stage III sporulation protein AE
KNAKPFIF_02550 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KNAKPFIF_02551 7.6e-29 spoIIIAC S stage III sporulation protein AC
KNAKPFIF_02552 2.9e-85 spoIIIAB S Stage III sporulation protein
KNAKPFIF_02553 1.2e-171 spoIIIAA S stage III sporulation protein AA
KNAKPFIF_02554 7.9e-37 yqhV S Protein of unknown function (DUF2619)
KNAKPFIF_02555 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KNAKPFIF_02556 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KNAKPFIF_02557 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KNAKPFIF_02558 2.3e-93 yqhR S Conserved membrane protein YqhR
KNAKPFIF_02559 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
KNAKPFIF_02560 2.2e-61 yqhP
KNAKPFIF_02561 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
KNAKPFIF_02562 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KNAKPFIF_02563 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KNAKPFIF_02564 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
KNAKPFIF_02565 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KNAKPFIF_02566 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KNAKPFIF_02567 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KNAKPFIF_02568 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KNAKPFIF_02569 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
KNAKPFIF_02570 1.2e-24 sinI S Anti-repressor SinI
KNAKPFIF_02571 1e-54 sinR K transcriptional
KNAKPFIF_02572 2.3e-142 tasA S Cell division protein FtsN
KNAKPFIF_02573 6.7e-59 sipW 3.4.21.89 U Signal peptidase
KNAKPFIF_02574 2.1e-116 yqxM
KNAKPFIF_02575 7.3e-54 yqzG S Protein of unknown function (DUF3889)
KNAKPFIF_02576 1.4e-26 yqzE S YqzE-like protein
KNAKPFIF_02577 3.7e-42 S ComG operon protein 7
KNAKPFIF_02578 5.5e-49 comGF U Putative Competence protein ComGF
KNAKPFIF_02579 1.1e-59 comGE
KNAKPFIF_02580 4.4e-71 gspH NU protein transport across the cell outer membrane
KNAKPFIF_02581 1.4e-47 comGC U Required for transformation and DNA binding
KNAKPFIF_02582 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
KNAKPFIF_02583 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KNAKPFIF_02585 7.2e-175 corA P Mg2 transporter protein
KNAKPFIF_02586 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KNAKPFIF_02587 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KNAKPFIF_02589 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
KNAKPFIF_02590 1.8e-37 yqgY S Protein of unknown function (DUF2626)
KNAKPFIF_02591 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KNAKPFIF_02592 8.9e-23 yqgW S Protein of unknown function (DUF2759)
KNAKPFIF_02593 6.9e-50 yqgV S Thiamine-binding protein
KNAKPFIF_02594 2.7e-199 yqgU
KNAKPFIF_02595 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KNAKPFIF_02596 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KNAKPFIF_02597 5.2e-181 glcK 2.7.1.2 G Glucokinase
KNAKPFIF_02598 3.1e-33 yqgQ S Protein conserved in bacteria
KNAKPFIF_02599 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KNAKPFIF_02600 2.5e-09 yqgO
KNAKPFIF_02601 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KNAKPFIF_02602 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KNAKPFIF_02603 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
KNAKPFIF_02605 9.2e-51 yqzD
KNAKPFIF_02606 1.9e-75 yqzC S YceG-like family
KNAKPFIF_02607 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNAKPFIF_02608 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KNAKPFIF_02609 4.4e-158 pstA P Phosphate transport system permease
KNAKPFIF_02610 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
KNAKPFIF_02611 5.3e-151 pstS P Phosphate
KNAKPFIF_02612 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KNAKPFIF_02613 2.5e-231 yqgE EGP Major facilitator superfamily
KNAKPFIF_02614 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KNAKPFIF_02615 4e-73 yqgC S protein conserved in bacteria
KNAKPFIF_02616 8.5e-134 yqgB S Protein of unknown function (DUF1189)
KNAKPFIF_02617 2.2e-75 yqgA
KNAKPFIF_02618 5.2e-47 yqfZ M LysM domain
KNAKPFIF_02619 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KNAKPFIF_02620 4.3e-62 yqfX S membrane
KNAKPFIF_02621 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KNAKPFIF_02622 1.9e-77 zur P Belongs to the Fur family
KNAKPFIF_02623 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KNAKPFIF_02624 2.1e-36 yqfT S Protein of unknown function (DUF2624)
KNAKPFIF_02625 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KNAKPFIF_02626 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KNAKPFIF_02627 2.9e-14 yqfQ S YqfQ-like protein
KNAKPFIF_02628 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KNAKPFIF_02629 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KNAKPFIF_02630 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
KNAKPFIF_02631 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
KNAKPFIF_02632 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KNAKPFIF_02633 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KNAKPFIF_02634 4.5e-88 yaiI S Belongs to the UPF0178 family
KNAKPFIF_02635 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KNAKPFIF_02636 4.5e-112 ccpN K CBS domain
KNAKPFIF_02637 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KNAKPFIF_02638 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KNAKPFIF_02639 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
KNAKPFIF_02640 8.4e-19 S YqzL-like protein
KNAKPFIF_02641 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KNAKPFIF_02642 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KNAKPFIF_02643 7.9e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KNAKPFIF_02644 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KNAKPFIF_02645 0.0 yqfF S membrane-associated HD superfamily hydrolase
KNAKPFIF_02647 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
KNAKPFIF_02648 5.6e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KNAKPFIF_02649 2.7e-45 yqfC S sporulation protein YqfC
KNAKPFIF_02650 1.3e-19 yqfB
KNAKPFIF_02651 4.3e-122 yqfA S UPF0365 protein
KNAKPFIF_02652 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KNAKPFIF_02653 2.5e-61 yqeY S Yqey-like protein
KNAKPFIF_02654 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KNAKPFIF_02655 1.6e-158 yqeW P COG1283 Na phosphate symporter
KNAKPFIF_02656 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KNAKPFIF_02657 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KNAKPFIF_02658 5.4e-175 prmA J Methylates ribosomal protein L11
KNAKPFIF_02659 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KNAKPFIF_02660 0.0 dnaK O Heat shock 70 kDa protein
KNAKPFIF_02661 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KNAKPFIF_02662 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KNAKPFIF_02663 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
KNAKPFIF_02664 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KNAKPFIF_02665 1e-54 yqxA S Protein of unknown function (DUF3679)
KNAKPFIF_02666 6.9e-223 spoIIP M stage II sporulation protein P
KNAKPFIF_02667 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KNAKPFIF_02668 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
KNAKPFIF_02669 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
KNAKPFIF_02670 4.1e-15 S YqzM-like protein
KNAKPFIF_02671 0.0 comEC S Competence protein ComEC
KNAKPFIF_02672 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
KNAKPFIF_02673 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
KNAKPFIF_02674 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KNAKPFIF_02675 2.9e-139 yqeM Q Methyltransferase
KNAKPFIF_02676 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KNAKPFIF_02677 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KNAKPFIF_02678 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KNAKPFIF_02679 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KNAKPFIF_02680 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KNAKPFIF_02681 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KNAKPFIF_02682 5.3e-95 yqeG S hydrolase of the HAD superfamily
KNAKPFIF_02684 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
KNAKPFIF_02685 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KNAKPFIF_02686 4.7e-106 yqeD S SNARE associated Golgi protein
KNAKPFIF_02687 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KNAKPFIF_02688 2.3e-133 yqeB
KNAKPFIF_02689 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
KNAKPFIF_02690 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNAKPFIF_02691 1.4e-281 cisA2 L Recombinase
KNAKPFIF_02692 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KNAKPFIF_02693 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
KNAKPFIF_02694 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNAKPFIF_02695 1.6e-54 arsR K ArsR family transcriptional regulator
KNAKPFIF_02696 1.1e-152 yqcI S YqcI/YcgG family
KNAKPFIF_02697 1.6e-96 S Tetratricopeptide repeat
KNAKPFIF_02700 3.8e-277 A Pre-toxin TG
KNAKPFIF_02701 1.1e-104 S Suppressor of fused protein (SUFU)
KNAKPFIF_02703 5e-60
KNAKPFIF_02705 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KNAKPFIF_02706 2.6e-68 S Bacteriophage holin family
KNAKPFIF_02707 4.8e-165 xepA
KNAKPFIF_02708 1.3e-23
KNAKPFIF_02709 4.1e-56 xkdW S XkdW protein
KNAKPFIF_02710 2e-221
KNAKPFIF_02711 9.6e-40
KNAKPFIF_02712 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KNAKPFIF_02713 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KNAKPFIF_02714 9.6e-71 xkdS S Protein of unknown function (DUF2634)
KNAKPFIF_02715 1.8e-38 xkdR S Protein of unknown function (DUF2577)
KNAKPFIF_02716 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
KNAKPFIF_02717 9e-114 xkdP S Lysin motif
KNAKPFIF_02718 0.0 xkdO L Transglycosylase SLT domain
KNAKPFIF_02719 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
KNAKPFIF_02721 3.6e-76 xkdM S Phage tail tube protein
KNAKPFIF_02722 5.5e-256 xkdK S Phage tail sheath C-terminal domain
KNAKPFIF_02723 3.2e-26
KNAKPFIF_02724 1.4e-77
KNAKPFIF_02725 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
KNAKPFIF_02726 6.7e-65 yqbH S Domain of unknown function (DUF3599)
KNAKPFIF_02727 2.1e-67 S Protein of unknown function (DUF3199)
KNAKPFIF_02728 3.6e-51 S YqbF, hypothetical protein domain
KNAKPFIF_02729 1.9e-167 xkdG S Phage capsid family
KNAKPFIF_02730 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KNAKPFIF_02731 2e-115
KNAKPFIF_02732 5.7e-169 S Phage Mu protein F like protein
KNAKPFIF_02733 5.9e-296 yqbA S portal protein
KNAKPFIF_02734 2.4e-253 S phage terminase, large subunit
KNAKPFIF_02735 6.3e-107 yqaS L DNA packaging
KNAKPFIF_02737 6.5e-81 L Transposase
KNAKPFIF_02738 1.6e-166
KNAKPFIF_02739 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
KNAKPFIF_02740 7.2e-74 rusA L Endodeoxyribonuclease RusA
KNAKPFIF_02742 5.9e-168 xkdC L IstB-like ATP binding protein
KNAKPFIF_02743 4.7e-123 3.1.3.16 L DnaD domain protein
KNAKPFIF_02744 2.5e-155 recT L RecT family
KNAKPFIF_02745 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
KNAKPFIF_02749 1.2e-103
KNAKPFIF_02751 6.5e-37 K Helix-turn-helix XRE-family like proteins
KNAKPFIF_02752 1.1e-56 K sequence-specific DNA binding
KNAKPFIF_02754 1e-101 adk 2.7.4.3 F adenylate kinase activity
KNAKPFIF_02755 1.4e-100 yqaB E IrrE N-terminal-like domain
KNAKPFIF_02756 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KNAKPFIF_02757 2e-68 psiE S Protein PsiE homolog
KNAKPFIF_02758 9e-237 yrkQ T Histidine kinase
KNAKPFIF_02759 1.1e-127 T Transcriptional regulator
KNAKPFIF_02760 8.2e-224 yrkO P Protein of unknown function (DUF418)
KNAKPFIF_02761 6e-105 yrkN K Acetyltransferase (GNAT) family
KNAKPFIF_02762 1.5e-97 ywrO S Flavodoxin-like fold
KNAKPFIF_02763 2.8e-79 S Protein of unknown function with HXXEE motif
KNAKPFIF_02764 4.3e-117 yrkJ S membrane transporter protein
KNAKPFIF_02765 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
KNAKPFIF_02766 1.1e-219 yrkH P Rhodanese Homology Domain
KNAKPFIF_02767 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
KNAKPFIF_02768 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
KNAKPFIF_02769 7.8e-39 yrkD S protein conserved in bacteria
KNAKPFIF_02770 2.6e-108 yrkC G Cupin domain
KNAKPFIF_02772 4.8e-151 bltR K helix_turn_helix, mercury resistance
KNAKPFIF_02773 3.5e-211 blt EGP Major facilitator Superfamily
KNAKPFIF_02774 1.4e-83 bltD 2.3.1.57 K FR47-like protein
KNAKPFIF_02775 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KNAKPFIF_02776 2.1e-17 S YrzO-like protein
KNAKPFIF_02777 1.7e-171 yrdR EG EamA-like transporter family
KNAKPFIF_02778 5.9e-160 yrdQ K Transcriptional regulator
KNAKPFIF_02779 2e-199 trkA P Oxidoreductase
KNAKPFIF_02780 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
KNAKPFIF_02781 1.3e-66 yodA S tautomerase
KNAKPFIF_02782 7.7e-163 gltR K LysR substrate binding domain
KNAKPFIF_02784 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
KNAKPFIF_02785 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
KNAKPFIF_02786 3.3e-138 azlC E AzlC protein
KNAKPFIF_02787 2.2e-79 bkdR K helix_turn_helix ASNC type
KNAKPFIF_02788 4.1e-46 yrdF K ribonuclease inhibitor
KNAKPFIF_02789 4.1e-231 cypA C Cytochrome P450
KNAKPFIF_02790 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
KNAKPFIF_02791 1.9e-57 S Protein of unknown function (DUF2568)
KNAKPFIF_02792 1.2e-91 yrdA S DinB family
KNAKPFIF_02793 7.6e-168 aadK G Streptomycin adenylyltransferase
KNAKPFIF_02794 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KNAKPFIF_02795 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KNAKPFIF_02796 3e-125 yrpD S Domain of unknown function, YrpD
KNAKPFIF_02798 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KNAKPFIF_02799 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_02800 4.5e-188 yrpG C Aldo/keto reductase family
KNAKPFIF_02801 9.5e-226 yraO C Citrate transporter
KNAKPFIF_02802 1.2e-163 yraN K Transcriptional regulator
KNAKPFIF_02803 2.4e-206 yraM S PrpF protein
KNAKPFIF_02805 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KNAKPFIF_02806 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNAKPFIF_02807 3.2e-155 S Alpha beta hydrolase
KNAKPFIF_02808 1.7e-60 T sh3 domain protein
KNAKPFIF_02809 2.4e-61 T sh3 domain protein
KNAKPFIF_02810 1.3e-66 E Glyoxalase-like domain
KNAKPFIF_02811 5.3e-37 yraG
KNAKPFIF_02812 6.4e-63 yraF M Spore coat protein
KNAKPFIF_02813 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KNAKPFIF_02814 2.6e-26 yraE
KNAKPFIF_02815 1.1e-49 yraD M Spore coat protein
KNAKPFIF_02816 4.3e-47 yraB K helix_turn_helix, mercury resistance
KNAKPFIF_02817 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
KNAKPFIF_02818 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
KNAKPFIF_02819 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KNAKPFIF_02820 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KNAKPFIF_02821 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KNAKPFIF_02822 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KNAKPFIF_02823 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
KNAKPFIF_02824 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
KNAKPFIF_02825 0.0 levR K PTS system fructose IIA component
KNAKPFIF_02826 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KNAKPFIF_02827 3.6e-106 yrhP E LysE type translocator
KNAKPFIF_02828 1.8e-150 yrhO K Archaeal transcriptional regulator TrmB
KNAKPFIF_02829 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_02830 1.9e-150 rsiV S Protein of unknown function (DUF3298)
KNAKPFIF_02831 0.0 yrhL I Acyltransferase family
KNAKPFIF_02832 1.5e-46 yrhK S YrhK-like protein
KNAKPFIF_02833 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KNAKPFIF_02834 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KNAKPFIF_02835 4.5e-97 yrhH Q methyltransferase
KNAKPFIF_02838 1.8e-142 focA P Formate nitrite
KNAKPFIF_02839 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
KNAKPFIF_02840 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KNAKPFIF_02841 1.4e-78 yrhD S Protein of unknown function (DUF1641)
KNAKPFIF_02842 4.6e-35 yrhC S YrhC-like protein
KNAKPFIF_02843 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KNAKPFIF_02844 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KNAKPFIF_02845 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KNAKPFIF_02846 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KNAKPFIF_02847 7e-27 yrzA S Protein of unknown function (DUF2536)
KNAKPFIF_02848 4.2e-63 yrrS S Protein of unknown function (DUF1510)
KNAKPFIF_02849 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KNAKPFIF_02850 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KNAKPFIF_02851 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KNAKPFIF_02852 2.7e-246 yegQ O COG0826 Collagenase and related proteases
KNAKPFIF_02853 7.8e-174 yegQ O Peptidase U32
KNAKPFIF_02854 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
KNAKPFIF_02855 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KNAKPFIF_02856 1.2e-45 yrzB S Belongs to the UPF0473 family
KNAKPFIF_02857 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KNAKPFIF_02858 1.7e-41 yrzL S Belongs to the UPF0297 family
KNAKPFIF_02859 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KNAKPFIF_02860 7.8e-170 yrrI S AI-2E family transporter
KNAKPFIF_02861 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KNAKPFIF_02862 7.7e-141 glnH ET Belongs to the bacterial solute-binding protein 3 family
KNAKPFIF_02863 2.6e-107 gluC P ABC transporter
KNAKPFIF_02864 7.6e-107 glnP P ABC transporter
KNAKPFIF_02865 8e-08 S Protein of unknown function (DUF3918)
KNAKPFIF_02866 9.8e-31 yrzR
KNAKPFIF_02867 5e-81 yrrD S protein conserved in bacteria
KNAKPFIF_02868 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KNAKPFIF_02869 1.4e-15 S COG0457 FOG TPR repeat
KNAKPFIF_02870 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KNAKPFIF_02871 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
KNAKPFIF_02872 1.2e-70 cymR K Transcriptional regulator
KNAKPFIF_02873 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KNAKPFIF_02874 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KNAKPFIF_02875 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KNAKPFIF_02876 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
KNAKPFIF_02878 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
KNAKPFIF_02879 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KNAKPFIF_02880 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KNAKPFIF_02881 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KNAKPFIF_02882 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KNAKPFIF_02883 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
KNAKPFIF_02884 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KNAKPFIF_02885 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KNAKPFIF_02886 9.4e-49 yrzD S Post-transcriptional regulator
KNAKPFIF_02887 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KNAKPFIF_02888 2.2e-114 yrbG S membrane
KNAKPFIF_02889 1.2e-74 yrzE S Protein of unknown function (DUF3792)
KNAKPFIF_02890 1.1e-38 yajC U Preprotein translocase subunit YajC
KNAKPFIF_02891 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KNAKPFIF_02892 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KNAKPFIF_02893 2.6e-18 yrzS S Protein of unknown function (DUF2905)
KNAKPFIF_02894 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KNAKPFIF_02895 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KNAKPFIF_02896 4.8e-93 bofC S BofC C-terminal domain
KNAKPFIF_02897 5.3e-253 csbX EGP Major facilitator Superfamily
KNAKPFIF_02898 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KNAKPFIF_02899 6.5e-119 yrzF T serine threonine protein kinase
KNAKPFIF_02901 2.6e-35 S Family of unknown function (DUF5412)
KNAKPFIF_02902 1.8e-262 alsT E Sodium alanine symporter
KNAKPFIF_02903 1.9e-127 yebC K transcriptional regulatory protein
KNAKPFIF_02904 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KNAKPFIF_02905 9.8e-158 safA M spore coat assembly protein SafA
KNAKPFIF_02906 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KNAKPFIF_02907 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KNAKPFIF_02908 4.7e-304 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KNAKPFIF_02909 9.8e-230 nifS 2.8.1.7 E Cysteine desulfurase
KNAKPFIF_02910 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
KNAKPFIF_02911 3.3e-163 pheA 4.2.1.51 E Prephenate dehydratase
KNAKPFIF_02912 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KNAKPFIF_02913 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KNAKPFIF_02914 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KNAKPFIF_02915 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KNAKPFIF_02916 4.1e-56 ysxB J ribosomal protein
KNAKPFIF_02917 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KNAKPFIF_02918 2e-160 spoIVFB S Stage IV sporulation protein
KNAKPFIF_02919 1.4e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KNAKPFIF_02920 3.3e-144 minD D Belongs to the ParA family
KNAKPFIF_02921 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KNAKPFIF_02922 1.4e-84 mreD M shape-determining protein
KNAKPFIF_02923 1.1e-156 mreC M Involved in formation and maintenance of cell shape
KNAKPFIF_02924 1.8e-184 mreB D Rod shape-determining protein MreB
KNAKPFIF_02925 1.3e-125 radC E Belongs to the UPF0758 family
KNAKPFIF_02926 2.4e-101 maf D septum formation protein Maf
KNAKPFIF_02927 6e-164 spoIIB S Sporulation related domain
KNAKPFIF_02928 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KNAKPFIF_02929 2.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KNAKPFIF_02930 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KNAKPFIF_02931 1.6e-25
KNAKPFIF_02932 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KNAKPFIF_02933 3.3e-186 spoVID M stage VI sporulation protein D
KNAKPFIF_02934 9.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KNAKPFIF_02935 1.1e-181 hemB 4.2.1.24 H Belongs to the ALAD family
KNAKPFIF_02936 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KNAKPFIF_02937 5.7e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KNAKPFIF_02938 3.6e-146 hemX O cytochrome C
KNAKPFIF_02939 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KNAKPFIF_02940 5.4e-89 ysxD
KNAKPFIF_02941 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KNAKPFIF_02942 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KNAKPFIF_02943 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KNAKPFIF_02944 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KNAKPFIF_02945 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KNAKPFIF_02946 2.3e-187 ysoA H Tetratricopeptide repeat
KNAKPFIF_02947 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNAKPFIF_02948 9.1e-46 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNAKPFIF_02949 1.2e-242 tetL EGP Major Facilitator Superfamily
KNAKPFIF_02950 1.8e-220 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KNAKPFIF_02951 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KNAKPFIF_02952 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KNAKPFIF_02953 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KNAKPFIF_02954 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
KNAKPFIF_02955 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KNAKPFIF_02957 3.6e-64 ysnE K acetyltransferase
KNAKPFIF_02958 1.6e-130 ysnF S protein conserved in bacteria
KNAKPFIF_02960 1.4e-92 ysnB S Phosphoesterase
KNAKPFIF_02961 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KNAKPFIF_02962 1.2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KNAKPFIF_02963 2.9e-196 gerM S COG5401 Spore germination protein
KNAKPFIF_02964 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KNAKPFIF_02965 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KNAKPFIF_02966 3.3e-30 gerE K Transcriptional regulator
KNAKPFIF_02967 9.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KNAKPFIF_02968 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KNAKPFIF_02969 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KNAKPFIF_02970 2.4e-107 sdhC C succinate dehydrogenase
KNAKPFIF_02971 1.2e-79 yslB S Protein of unknown function (DUF2507)
KNAKPFIF_02972 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KNAKPFIF_02973 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KNAKPFIF_02974 2e-52 trxA O Belongs to the thioredoxin family
KNAKPFIF_02975 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KNAKPFIF_02977 7.9e-177 etfA C Electron transfer flavoprotein
KNAKPFIF_02978 4.5e-135 etfB C Electron transfer flavoprotein
KNAKPFIF_02979 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KNAKPFIF_02980 4e-99 fadR K Transcriptional regulator
KNAKPFIF_02981 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KNAKPFIF_02982 7.3e-68 yshE S membrane
KNAKPFIF_02983 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KNAKPFIF_02984 0.0 polX L COG1796 DNA polymerase IV (family X)
KNAKPFIF_02985 3.9e-85 cvpA S membrane protein, required for colicin V production
KNAKPFIF_02986 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KNAKPFIF_02987 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KNAKPFIF_02988 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNAKPFIF_02989 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KNAKPFIF_02990 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KNAKPFIF_02991 2.6e-32 sspI S Belongs to the SspI family
KNAKPFIF_02992 3.7e-207 ysfB KT regulator
KNAKPFIF_02993 1.6e-258 glcD 1.1.3.15 C Glycolate oxidase subunit
KNAKPFIF_02994 3.5e-252 glcF C Glycolate oxidase
KNAKPFIF_02995 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
KNAKPFIF_02997 0.0 cstA T Carbon starvation protein
KNAKPFIF_02998 1.1e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KNAKPFIF_02999 3.8e-143 araQ G transport system permease
KNAKPFIF_03000 4.2e-167 araP G carbohydrate transport
KNAKPFIF_03001 2.9e-251 araN G carbohydrate transport
KNAKPFIF_03002 3.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KNAKPFIF_03003 8.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KNAKPFIF_03004 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KNAKPFIF_03005 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KNAKPFIF_03006 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KNAKPFIF_03007 1.2e-99 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KNAKPFIF_03008 7.9e-57 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KNAKPFIF_03009 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
KNAKPFIF_03010 9.2e-68 ysdB S Sigma-w pathway protein YsdB
KNAKPFIF_03011 1.7e-44 ysdA S Membrane
KNAKPFIF_03012 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KNAKPFIF_03013 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KNAKPFIF_03014 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KNAKPFIF_03016 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KNAKPFIF_03017 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KNAKPFIF_03018 7.8e-129 lytT T COG3279 Response regulator of the LytR AlgR family
KNAKPFIF_03019 0.0 lytS 2.7.13.3 T Histidine kinase
KNAKPFIF_03020 1.1e-147 ysaA S HAD-hyrolase-like
KNAKPFIF_03021 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNAKPFIF_03023 1.1e-155 ytxC S YtxC-like family
KNAKPFIF_03024 4.9e-111 ytxB S SNARE associated Golgi protein
KNAKPFIF_03025 6.6e-173 dnaI L Primosomal protein DnaI
KNAKPFIF_03026 2.9e-265 dnaB L Membrane attachment protein
KNAKPFIF_03027 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KNAKPFIF_03028 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KNAKPFIF_03029 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KNAKPFIF_03030 8.4e-66 ytcD K Transcriptional regulator
KNAKPFIF_03031 4.9e-205 ytbD EGP Major facilitator Superfamily
KNAKPFIF_03032 8.9e-161 ytbE S reductase
KNAKPFIF_03033 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KNAKPFIF_03034 1.1e-107 ytaF P Probably functions as a manganese efflux pump
KNAKPFIF_03035 2.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KNAKPFIF_03036 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KNAKPFIF_03037 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KNAKPFIF_03038 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_03039 1.2e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KNAKPFIF_03040 4.1e-242 icd 1.1.1.42 C isocitrate
KNAKPFIF_03041 1.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
KNAKPFIF_03042 5.2e-70 yeaL S membrane
KNAKPFIF_03043 2.6e-192 ytvI S sporulation integral membrane protein YtvI
KNAKPFIF_03044 4.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KNAKPFIF_03045 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KNAKPFIF_03046 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KNAKPFIF_03047 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KNAKPFIF_03048 9.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KNAKPFIF_03049 2e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KNAKPFIF_03050 0.0 dnaE 2.7.7.7 L DNA polymerase
KNAKPFIF_03051 3.2e-56 ytrH S Sporulation protein YtrH
KNAKPFIF_03052 8.2e-69 ytrI
KNAKPFIF_03053 9.2e-29
KNAKPFIF_03054 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KNAKPFIF_03055 2.4e-47 ytpI S YtpI-like protein
KNAKPFIF_03056 8e-241 ytoI K transcriptional regulator containing CBS domains
KNAKPFIF_03057 1.2e-158 ytnM S membrane transporter protein
KNAKPFIF_03058 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
KNAKPFIF_03059 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
KNAKPFIF_03060 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNAKPFIF_03061 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
KNAKPFIF_03062 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNAKPFIF_03063 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KNAKPFIF_03064 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
KNAKPFIF_03065 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
KNAKPFIF_03066 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
KNAKPFIF_03067 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
KNAKPFIF_03068 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
KNAKPFIF_03069 2.9e-173 ytlI K LysR substrate binding domain
KNAKPFIF_03070 1.7e-130 ytkL S Belongs to the UPF0173 family
KNAKPFIF_03071 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_03073 3.4e-266 argH 4.3.2.1 E argininosuccinate lyase
KNAKPFIF_03074 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KNAKPFIF_03075 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KNAKPFIF_03076 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KNAKPFIF_03077 5.4e-165 ytxK 2.1.1.72 L DNA methylase
KNAKPFIF_03078 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KNAKPFIF_03079 8.7e-70 ytfJ S Sporulation protein YtfJ
KNAKPFIF_03080 5.6e-116 ytfI S Protein of unknown function (DUF2953)
KNAKPFIF_03081 2.5e-86 yteJ S RDD family
KNAKPFIF_03082 1.3e-177 sppA OU signal peptide peptidase SppA
KNAKPFIF_03083 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KNAKPFIF_03084 0.0 ytcJ S amidohydrolase
KNAKPFIF_03085 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KNAKPFIF_03086 2e-29 sspB S spore protein
KNAKPFIF_03087 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KNAKPFIF_03088 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
KNAKPFIF_03089 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
KNAKPFIF_03090 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KNAKPFIF_03091 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KNAKPFIF_03092 3.4e-109 yttP K Transcriptional regulator
KNAKPFIF_03093 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KNAKPFIF_03094 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KNAKPFIF_03095 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KNAKPFIF_03097 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNAKPFIF_03098 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KNAKPFIF_03099 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KNAKPFIF_03100 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
KNAKPFIF_03101 1.9e-225 acuC BQ histone deacetylase
KNAKPFIF_03102 1.4e-125 motS N Flagellar motor protein
KNAKPFIF_03103 7.1e-147 motA N flagellar motor
KNAKPFIF_03104 1.7e-182 ccpA K catabolite control protein A
KNAKPFIF_03105 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KNAKPFIF_03106 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
KNAKPFIF_03107 6.6e-17 ytxH S COG4980 Gas vesicle protein
KNAKPFIF_03108 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KNAKPFIF_03109 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KNAKPFIF_03110 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KNAKPFIF_03111 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KNAKPFIF_03112 9.8e-149 ytpQ S Belongs to the UPF0354 family
KNAKPFIF_03113 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KNAKPFIF_03114 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KNAKPFIF_03115 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KNAKPFIF_03116 9.8e-52 ytzB S small secreted protein
KNAKPFIF_03117 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KNAKPFIF_03118 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KNAKPFIF_03119 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KNAKPFIF_03120 2e-45 ytzH S YtzH-like protein
KNAKPFIF_03121 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
KNAKPFIF_03122 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KNAKPFIF_03123 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KNAKPFIF_03124 1.3e-165 ytlQ
KNAKPFIF_03125 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KNAKPFIF_03126 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KNAKPFIF_03127 7.1e-272 pepV 3.5.1.18 E Dipeptidase
KNAKPFIF_03128 7.2e-226 pbuO S permease
KNAKPFIF_03129 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
KNAKPFIF_03130 4.3e-132 ythP V ABC transporter
KNAKPFIF_03131 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KNAKPFIF_03132 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KNAKPFIF_03133 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KNAKPFIF_03134 8.2e-232 ytfP S HI0933-like protein
KNAKPFIF_03135 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KNAKPFIF_03136 3.1e-26 yteV S Sporulation protein Cse60
KNAKPFIF_03137 4.8e-117 yteU S Integral membrane protein
KNAKPFIF_03138 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
KNAKPFIF_03139 4.6e-73 yteS G transport
KNAKPFIF_03140 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KNAKPFIF_03141 2.2e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KNAKPFIF_03142 1.4e-163 ytdP K Transcriptional regulator
KNAKPFIF_03143 3.7e-221 ytdP K Transcriptional regulator
KNAKPFIF_03144 2.4e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
KNAKPFIF_03145 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
KNAKPFIF_03146 8.1e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
KNAKPFIF_03147 3.5e-219 bioI 1.14.14.46 C Cytochrome P450
KNAKPFIF_03148 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KNAKPFIF_03149 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KNAKPFIF_03150 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KNAKPFIF_03151 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KNAKPFIF_03152 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KNAKPFIF_03153 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
KNAKPFIF_03154 2.3e-190 msmR K Transcriptional regulator
KNAKPFIF_03155 2.1e-246 msmE G Bacterial extracellular solute-binding protein
KNAKPFIF_03156 1.5e-169 amyD P ABC transporter
KNAKPFIF_03157 1.5e-144 amyC P ABC transporter (permease)
KNAKPFIF_03158 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KNAKPFIF_03159 2.1e-51 ytwF P Sulfurtransferase
KNAKPFIF_03160 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KNAKPFIF_03161 7.7e-55 ytvB S Protein of unknown function (DUF4257)
KNAKPFIF_03162 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KNAKPFIF_03163 2.1e-211 yttB EGP Major facilitator Superfamily
KNAKPFIF_03164 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
KNAKPFIF_03165 0.0 bceB V ABC transporter (permease)
KNAKPFIF_03166 1.1e-138 bceA V ABC transporter, ATP-binding protein
KNAKPFIF_03167 5.6e-186 T PhoQ Sensor
KNAKPFIF_03168 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_03169 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KNAKPFIF_03170 3.1e-127 ytrE V ABC transporter, ATP-binding protein
KNAKPFIF_03171 5.9e-148
KNAKPFIF_03172 6.1e-169 P ABC-2 family transporter protein
KNAKPFIF_03173 1.1e-161 ytrB P abc transporter atp-binding protein
KNAKPFIF_03174 5.1e-66 ytrA K GntR family transcriptional regulator
KNAKPFIF_03176 6.7e-41 ytzC S Protein of unknown function (DUF2524)
KNAKPFIF_03177 2.1e-190 yhcC S Fe-S oxidoreductase
KNAKPFIF_03178 3.3e-106 ytqB J Putative rRNA methylase
KNAKPFIF_03179 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KNAKPFIF_03180 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KNAKPFIF_03181 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KNAKPFIF_03182 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KNAKPFIF_03183 0.0 asnB 6.3.5.4 E Asparagine synthase
KNAKPFIF_03184 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KNAKPFIF_03185 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KNAKPFIF_03186 1.2e-38 ytmB S Protein of unknown function (DUF2584)
KNAKPFIF_03187 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KNAKPFIF_03188 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KNAKPFIF_03189 1.4e-144 ytlC P ABC transporter
KNAKPFIF_03190 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KNAKPFIF_03191 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KNAKPFIF_03192 5.4e-63 ytkC S Bacteriophage holin family
KNAKPFIF_03193 2.1e-76 dps P Belongs to the Dps family
KNAKPFIF_03195 3.6e-73 ytkA S YtkA-like
KNAKPFIF_03196 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KNAKPFIF_03197 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KNAKPFIF_03198 3.6e-41 rpmE2 J Ribosomal protein L31
KNAKPFIF_03199 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
KNAKPFIF_03200 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KNAKPFIF_03201 1.1e-24 S Domain of Unknown Function (DUF1540)
KNAKPFIF_03202 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KNAKPFIF_03203 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KNAKPFIF_03204 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KNAKPFIF_03205 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
KNAKPFIF_03206 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KNAKPFIF_03207 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KNAKPFIF_03208 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KNAKPFIF_03209 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KNAKPFIF_03210 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KNAKPFIF_03211 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
KNAKPFIF_03212 2.6e-132 dksA T COG1734 DnaK suppressor protein
KNAKPFIF_03213 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
KNAKPFIF_03214 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNAKPFIF_03215 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
KNAKPFIF_03216 3.6e-235 ytcC M Glycosyltransferase Family 4
KNAKPFIF_03218 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
KNAKPFIF_03219 1.8e-217 cotSA M Glycosyl transferases group 1
KNAKPFIF_03220 1.8e-206 cotI S Spore coat protein
KNAKPFIF_03221 9.9e-77 tspO T membrane
KNAKPFIF_03222 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KNAKPFIF_03223 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KNAKPFIF_03224 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KNAKPFIF_03225 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KNAKPFIF_03226 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KNAKPFIF_03235 7.8e-08
KNAKPFIF_03236 1.3e-09
KNAKPFIF_03243 2e-08
KNAKPFIF_03248 3.4e-39 S COG NOG14552 non supervised orthologous group
KNAKPFIF_03249 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
KNAKPFIF_03250 3.4e-94 M1-753 M FR47-like protein
KNAKPFIF_03251 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
KNAKPFIF_03252 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KNAKPFIF_03253 3.9e-84 yuaE S DinB superfamily
KNAKPFIF_03254 7.9e-108 yuaD
KNAKPFIF_03255 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
KNAKPFIF_03256 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KNAKPFIF_03257 1.1e-95 yuaC K Belongs to the GbsR family
KNAKPFIF_03258 2.2e-91 yuaB
KNAKPFIF_03259 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
KNAKPFIF_03260 5.4e-237 ktrB P Potassium
KNAKPFIF_03261 1e-38 yiaA S yiaA/B two helix domain
KNAKPFIF_03262 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KNAKPFIF_03263 6.2e-277 yubD P Major Facilitator Superfamily
KNAKPFIF_03264 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
KNAKPFIF_03266 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KNAKPFIF_03267 6.3e-197 yubA S transporter activity
KNAKPFIF_03268 3.3e-183 ygjR S Oxidoreductase
KNAKPFIF_03269 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KNAKPFIF_03270 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KNAKPFIF_03271 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KNAKPFIF_03272 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
KNAKPFIF_03273 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
KNAKPFIF_03274 5.1e-239 mcpA NT chemotaxis protein
KNAKPFIF_03275 2.2e-295 mcpA NT chemotaxis protein
KNAKPFIF_03276 1.5e-222 mcpA NT chemotaxis protein
KNAKPFIF_03277 3.2e-225 mcpA NT chemotaxis protein
KNAKPFIF_03278 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KNAKPFIF_03279 1e-35
KNAKPFIF_03280 2.1e-72 yugU S Uncharacterised protein family UPF0047
KNAKPFIF_03281 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KNAKPFIF_03282 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KNAKPFIF_03283 1.4e-116 yugP S Zn-dependent protease
KNAKPFIF_03284 4.6e-39
KNAKPFIF_03285 1.1e-53 mstX S Membrane-integrating protein Mistic
KNAKPFIF_03286 1.7e-182 yugO P COG1226 Kef-type K transport systems
KNAKPFIF_03287 1.3e-72 yugN S YugN-like family
KNAKPFIF_03289 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
KNAKPFIF_03290 2.8e-229 yugK C Dehydrogenase
KNAKPFIF_03291 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KNAKPFIF_03292 1.1e-34 yuzA S Domain of unknown function (DUF378)
KNAKPFIF_03293 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KNAKPFIF_03294 4.3e-200 yugH 2.6.1.1 E Aminotransferase
KNAKPFIF_03295 1.6e-85 alaR K Transcriptional regulator
KNAKPFIF_03296 1e-156 yugF I Hydrolase
KNAKPFIF_03297 9.8e-42 yugE S Domain of unknown function (DUF1871)
KNAKPFIF_03298 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KNAKPFIF_03299 7.8e-233 T PhoQ Sensor
KNAKPFIF_03300 2e-70 kapB G Kinase associated protein B
KNAKPFIF_03301 1.9e-115 kapD L the KinA pathway to sporulation
KNAKPFIF_03303 3.5e-186 yuxJ EGP Major facilitator Superfamily
KNAKPFIF_03304 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KNAKPFIF_03305 6.3e-75 yuxK S protein conserved in bacteria
KNAKPFIF_03306 6.3e-78 yufK S Family of unknown function (DUF5366)
KNAKPFIF_03307 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KNAKPFIF_03308 1.5e-124 dcuR T COG4565 Response regulator of citrate malate metabolism
KNAKPFIF_03309 6.7e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KNAKPFIF_03310 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KNAKPFIF_03311 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KNAKPFIF_03312 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
KNAKPFIF_03313 1.3e-233 maeN C COG3493 Na citrate symporter
KNAKPFIF_03314 3.2e-14
KNAKPFIF_03315 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KNAKPFIF_03316 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KNAKPFIF_03317 3.4e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KNAKPFIF_03318 3.9e-260 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KNAKPFIF_03319 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KNAKPFIF_03320 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KNAKPFIF_03321 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KNAKPFIF_03322 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
KNAKPFIF_03323 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNAKPFIF_03324 0.0 comP 2.7.13.3 T Histidine kinase
KNAKPFIF_03326 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
KNAKPFIF_03328 1.1e-22 yuzC
KNAKPFIF_03329 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KNAKPFIF_03330 1e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KNAKPFIF_03331 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
KNAKPFIF_03332 1.8e-66 yueI S Protein of unknown function (DUF1694)
KNAKPFIF_03333 7.4e-39 yueH S YueH-like protein
KNAKPFIF_03334 2.5e-30 yueG S Spore germination protein gerPA/gerPF
KNAKPFIF_03335 3.2e-190 yueF S transporter activity
KNAKPFIF_03336 6.1e-72 S Protein of unknown function (DUF2283)
KNAKPFIF_03337 4.8e-96 yueE S phosphohydrolase
KNAKPFIF_03338 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_03339 6.6e-65 yueC S Family of unknown function (DUF5383)
KNAKPFIF_03340 0.0 esaA S type VII secretion protein EsaA
KNAKPFIF_03341 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KNAKPFIF_03342 2.4e-208 essB S WXG100 protein secretion system (Wss), protein YukC
KNAKPFIF_03343 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
KNAKPFIF_03344 2.8e-45 esxA S Belongs to the WXG100 family
KNAKPFIF_03345 4.2e-228 yukF QT Transcriptional regulator
KNAKPFIF_03346 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KNAKPFIF_03347 1.2e-131 yukJ S Uncharacterized conserved protein (DUF2278)
KNAKPFIF_03348 1.4e-35 mbtH S MbtH-like protein
KNAKPFIF_03349 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_03350 2.2e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KNAKPFIF_03351 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KNAKPFIF_03352 1.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
KNAKPFIF_03353 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_03354 1.1e-166 besA S Putative esterase
KNAKPFIF_03355 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
KNAKPFIF_03356 1.1e-93 bioY S Biotin biosynthesis protein
KNAKPFIF_03357 3.9e-211 yuiF S antiporter
KNAKPFIF_03358 1e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KNAKPFIF_03359 1.2e-77 yuiD S protein conserved in bacteria
KNAKPFIF_03360 4.7e-117 yuiC S protein conserved in bacteria
KNAKPFIF_03361 1.9e-26 yuiB S Putative membrane protein
KNAKPFIF_03362 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
KNAKPFIF_03363 1e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
KNAKPFIF_03365 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KNAKPFIF_03366 3.8e-116 paiB K Putative FMN-binding domain
KNAKPFIF_03367 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNAKPFIF_03368 3.7e-63 erpA S Belongs to the HesB IscA family
KNAKPFIF_03369 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KNAKPFIF_03370 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNAKPFIF_03371 3.2e-39 yuzB S Belongs to the UPF0349 family
KNAKPFIF_03372 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
KNAKPFIF_03373 3.5e-57 yuzD S protein conserved in bacteria
KNAKPFIF_03374 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KNAKPFIF_03375 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KNAKPFIF_03376 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KNAKPFIF_03377 2.6e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KNAKPFIF_03378 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
KNAKPFIF_03379 2.9e-198 yutH S Spore coat protein
KNAKPFIF_03380 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KNAKPFIF_03381 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KNAKPFIF_03382 1e-75 yutE S Protein of unknown function DUF86
KNAKPFIF_03383 9.7e-48 yutD S protein conserved in bacteria
KNAKPFIF_03384 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KNAKPFIF_03385 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KNAKPFIF_03386 1.7e-195 lytH M Peptidase, M23
KNAKPFIF_03387 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
KNAKPFIF_03388 4.1e-47 yunC S Domain of unknown function (DUF1805)
KNAKPFIF_03389 6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KNAKPFIF_03390 2e-141 yunE S membrane transporter protein
KNAKPFIF_03391 4.3e-171 yunF S Protein of unknown function DUF72
KNAKPFIF_03392 8.2e-60 yunG
KNAKPFIF_03393 4.7e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KNAKPFIF_03394 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
KNAKPFIF_03395 2e-234 pbuX F Permease family
KNAKPFIF_03396 4.8e-222 pbuX F xanthine
KNAKPFIF_03397 8.3e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KNAKPFIF_03398 3.2e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KNAKPFIF_03400 1.4e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KNAKPFIF_03401 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KNAKPFIF_03402 1.9e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KNAKPFIF_03403 2.2e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KNAKPFIF_03404 4.7e-185 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KNAKPFIF_03405 2.5e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KNAKPFIF_03406 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KNAKPFIF_03407 2.4e-169 bsn L Ribonuclease
KNAKPFIF_03408 1.2e-205 msmX P Belongs to the ABC transporter superfamily
KNAKPFIF_03409 1.1e-135 yurK K UTRA
KNAKPFIF_03410 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KNAKPFIF_03411 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
KNAKPFIF_03412 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
KNAKPFIF_03413 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KNAKPFIF_03414 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KNAKPFIF_03415 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KNAKPFIF_03416 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KNAKPFIF_03418 1e-41
KNAKPFIF_03419 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNAKPFIF_03420 3.5e-271 sufB O FeS cluster assembly
KNAKPFIF_03421 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KNAKPFIF_03422 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KNAKPFIF_03423 1.4e-245 sufD O assembly protein SufD
KNAKPFIF_03424 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KNAKPFIF_03425 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KNAKPFIF_03426 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
KNAKPFIF_03427 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KNAKPFIF_03428 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KNAKPFIF_03429 2.4e-56 yusD S SCP-2 sterol transfer family
KNAKPFIF_03430 5.6e-55 traF CO Thioredoxin
KNAKPFIF_03431 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KNAKPFIF_03432 1.1e-39 yusG S Protein of unknown function (DUF2553)
KNAKPFIF_03433 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KNAKPFIF_03434 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KNAKPFIF_03435 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KNAKPFIF_03436 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KNAKPFIF_03437 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KNAKPFIF_03438 4.7e-09 S YuzL-like protein
KNAKPFIF_03439 2.2e-165 fadM E Proline dehydrogenase
KNAKPFIF_03440 5.1e-40
KNAKPFIF_03441 3.2e-53 yusN M Coat F domain
KNAKPFIF_03442 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
KNAKPFIF_03443 3.8e-293 yusP P Major facilitator superfamily
KNAKPFIF_03444 8.4e-66 yusQ S Tautomerase enzyme
KNAKPFIF_03445 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_03446 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_03447 2.7e-160 yusT K LysR substrate binding domain
KNAKPFIF_03448 3.8e-47 yusU S Protein of unknown function (DUF2573)
KNAKPFIF_03449 1e-153 yusV 3.6.3.34 HP ABC transporter
KNAKPFIF_03450 5.6e-66 S YusW-like protein
KNAKPFIF_03451 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
KNAKPFIF_03452 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
KNAKPFIF_03453 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_03454 1.2e-79 dps P Ferritin-like domain
KNAKPFIF_03455 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNAKPFIF_03456 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_03457 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
KNAKPFIF_03458 4.3e-158 yuxN K Transcriptional regulator
KNAKPFIF_03459 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KNAKPFIF_03460 2.3e-24 S Protein of unknown function (DUF3970)
KNAKPFIF_03461 1e-244 gerAA EG Spore germination protein
KNAKPFIF_03462 3.8e-196 gerAB E Spore germination protein
KNAKPFIF_03463 2e-176 gerAC S Spore germination B3/ GerAC like, C-terminal
KNAKPFIF_03464 8.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNAKPFIF_03465 1.6e-186 vraS 2.7.13.3 T Histidine kinase
KNAKPFIF_03466 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KNAKPFIF_03467 3.1e-116 liaG S Putative adhesin
KNAKPFIF_03468 4.7e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KNAKPFIF_03469 7.3e-62 liaI S membrane
KNAKPFIF_03470 5.9e-225 yvqJ EGP Major facilitator Superfamily
KNAKPFIF_03471 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
KNAKPFIF_03472 2.1e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KNAKPFIF_03473 8.5e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_03474 6.9e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KNAKPFIF_03475 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_03476 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
KNAKPFIF_03477 0.0 T PhoQ Sensor
KNAKPFIF_03478 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_03479 4.5e-96 yvrI K RNA polymerase
KNAKPFIF_03480 2.4e-19 S YvrJ protein family
KNAKPFIF_03481 4.7e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
KNAKPFIF_03482 1.3e-64 yvrL S Regulatory protein YrvL
KNAKPFIF_03483 4.1e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
KNAKPFIF_03484 1.6e-123 macB V ABC transporter, ATP-binding protein
KNAKPFIF_03485 2e-174 M Efflux transporter rnd family, mfp subunit
KNAKPFIF_03486 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
KNAKPFIF_03487 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_03488 3.7e-180 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KNAKPFIF_03489 2.6e-177 fhuD P ABC transporter
KNAKPFIF_03490 4.9e-236 yvsH E Arginine ornithine antiporter
KNAKPFIF_03491 6.5e-16 S Small spore protein J (Spore_SspJ)
KNAKPFIF_03492 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KNAKPFIF_03493 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KNAKPFIF_03494 2.7e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KNAKPFIF_03495 3.5e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KNAKPFIF_03496 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
KNAKPFIF_03497 4.2e-155 yvgN S reductase
KNAKPFIF_03498 2.1e-85 yvgO
KNAKPFIF_03499 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KNAKPFIF_03500 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KNAKPFIF_03501 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KNAKPFIF_03502 0.0 helD 3.6.4.12 L DNA helicase
KNAKPFIF_03503 4.1e-107 yvgT S membrane
KNAKPFIF_03504 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
KNAKPFIF_03505 1.6e-104 bdbD O Thioredoxin
KNAKPFIF_03506 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KNAKPFIF_03507 0.0 copA 3.6.3.54 P P-type ATPase
KNAKPFIF_03508 1.5e-29 copZ P Copper resistance protein CopZ
KNAKPFIF_03509 2.2e-48 csoR S transcriptional
KNAKPFIF_03510 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
KNAKPFIF_03511 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KNAKPFIF_03512 0.0 yvaC S Fusaric acid resistance protein-like
KNAKPFIF_03513 5.7e-73 yvaD S Family of unknown function (DUF5360)
KNAKPFIF_03514 2.8e-55 yvaE P Small Multidrug Resistance protein
KNAKPFIF_03515 4.1e-101 K Bacterial regulatory proteins, tetR family
KNAKPFIF_03516 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_03518 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KNAKPFIF_03519 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KNAKPFIF_03520 5.6e-143 est 3.1.1.1 S Carboxylesterase
KNAKPFIF_03521 2.4e-23 secG U Preprotein translocase subunit SecG
KNAKPFIF_03522 3.7e-153 yvaM S Serine aminopeptidase, S33
KNAKPFIF_03523 7.5e-36 yvzC K Transcriptional
KNAKPFIF_03524 4e-69 K transcriptional
KNAKPFIF_03525 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
KNAKPFIF_03526 2.2e-54 yodB K transcriptional
KNAKPFIF_03527 4.2e-226 NT chemotaxis protein
KNAKPFIF_03528 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KNAKPFIF_03529 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KNAKPFIF_03530 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KNAKPFIF_03531 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KNAKPFIF_03532 8.7e-61 yvbF K Belongs to the GbsR family
KNAKPFIF_03533 7.9e-13 S Sporulation delaying protein SdpA
KNAKPFIF_03534 7.6e-172
KNAKPFIF_03535 4.4e-08
KNAKPFIF_03536 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KNAKPFIF_03537 4.5e-45 sdpR K transcriptional
KNAKPFIF_03538 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KNAKPFIF_03539 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KNAKPFIF_03540 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KNAKPFIF_03541 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KNAKPFIF_03542 1.4e-98 yvbF K Belongs to the GbsR family
KNAKPFIF_03543 6.4e-103 yvbG U UPF0056 membrane protein
KNAKPFIF_03544 8.6e-113 yvbH S YvbH-like oligomerisation region
KNAKPFIF_03545 4.2e-124 exoY M Membrane
KNAKPFIF_03546 0.0 tcaA S response to antibiotic
KNAKPFIF_03547 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
KNAKPFIF_03548 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KNAKPFIF_03549 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KNAKPFIF_03550 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KNAKPFIF_03551 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KNAKPFIF_03552 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KNAKPFIF_03553 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KNAKPFIF_03554 1.6e-252 araE EGP Major facilitator Superfamily
KNAKPFIF_03555 5.5e-203 araR K transcriptional
KNAKPFIF_03556 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNAKPFIF_03557 3.9e-159 yvbU K Transcriptional regulator
KNAKPFIF_03558 8.5e-157 yvbV EG EamA-like transporter family
KNAKPFIF_03559 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KNAKPFIF_03560 4.3e-197 yvbX S Glycosyl hydrolase
KNAKPFIF_03561 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KNAKPFIF_03562 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KNAKPFIF_03563 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KNAKPFIF_03564 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNAKPFIF_03565 8.9e-201 desK 2.7.13.3 T Histidine kinase
KNAKPFIF_03566 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
KNAKPFIF_03567 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
KNAKPFIF_03568 2.6e-157 rsbQ S Alpha/beta hydrolase family
KNAKPFIF_03569 1.4e-199 rsbU 3.1.3.3 T response regulator
KNAKPFIF_03570 2.6e-252 galA 3.2.1.89 G arabinogalactan
KNAKPFIF_03571 0.0 lacA 3.2.1.23 G beta-galactosidase
KNAKPFIF_03572 3.2e-150 ganQ P transport
KNAKPFIF_03573 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
KNAKPFIF_03574 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
KNAKPFIF_03575 1.8e-184 lacR K Transcriptional regulator
KNAKPFIF_03576 6.6e-111 yvfI K COG2186 Transcriptional regulators
KNAKPFIF_03577 1.4e-309 yvfH C L-lactate permease
KNAKPFIF_03578 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KNAKPFIF_03579 1e-31 yvfG S YvfG protein
KNAKPFIF_03580 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
KNAKPFIF_03581 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KNAKPFIF_03582 6.4e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KNAKPFIF_03583 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KNAKPFIF_03584 6.1e-253 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KNAKPFIF_03585 1.9e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KNAKPFIF_03586 3.5e-202 epsI GM pyruvyl transferase
KNAKPFIF_03587 6.4e-193 epsH GT2 S Glycosyltransferase like family 2
KNAKPFIF_03588 1.8e-206 epsG S EpsG family
KNAKPFIF_03589 3.2e-217 epsF GT4 M Glycosyl transferases group 1
KNAKPFIF_03590 1.7e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KNAKPFIF_03591 2.6e-219 epsD GT4 M Glycosyl transferase 4-like
KNAKPFIF_03592 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KNAKPFIF_03593 3.9e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KNAKPFIF_03594 4e-122 ywqC M biosynthesis protein
KNAKPFIF_03595 3.1e-75 slr K transcriptional
KNAKPFIF_03596 2.8e-279 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KNAKPFIF_03598 4.6e-93 padC Q Phenolic acid decarboxylase
KNAKPFIF_03599 7.3e-46 MA20_18690 S Protein of unknown function (DUF3237)
KNAKPFIF_03600 6.1e-16 MA20_18690 S Protein of unknown function (DUF3237)
KNAKPFIF_03601 5.4e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KNAKPFIF_03602 3.8e-262 pbpE V Beta-lactamase
KNAKPFIF_03603 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
KNAKPFIF_03604 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KNAKPFIF_03605 1.8e-295 yveA E amino acid
KNAKPFIF_03606 7.4e-106 yvdT K Transcriptional regulator
KNAKPFIF_03607 6.7e-51 ykkC P Small Multidrug Resistance protein
KNAKPFIF_03608 4.1e-50 sugE P Small Multidrug Resistance protein
KNAKPFIF_03609 3.9e-72 yvdQ S Protein of unknown function (DUF3231)
KNAKPFIF_03610 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
KNAKPFIF_03611 1.5e-183 S Patatin-like phospholipase
KNAKPFIF_03613 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KNAKPFIF_03614 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KNAKPFIF_03615 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KNAKPFIF_03616 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KNAKPFIF_03617 1.2e-158 malA S Protein of unknown function (DUF1189)
KNAKPFIF_03618 7.8e-149 malD P transport
KNAKPFIF_03619 1.3e-243 malC P COG1175 ABC-type sugar transport systems, permease components
KNAKPFIF_03620 9e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KNAKPFIF_03621 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KNAKPFIF_03622 6.1e-174 yvdE K Transcriptional regulator
KNAKPFIF_03623 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KNAKPFIF_03624 1.5e-29 yvdC S MazG nucleotide pyrophosphohydrolase domain
KNAKPFIF_03625 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KNAKPFIF_03626 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KNAKPFIF_03627 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KNAKPFIF_03628 0.0 yxdM V ABC transporter (permease)
KNAKPFIF_03629 5.6e-141 yvcR V ABC transporter, ATP-binding protein
KNAKPFIF_03630 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KNAKPFIF_03631 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_03632 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KNAKPFIF_03633 1.6e-36 crh G Phosphocarrier protein Chr
KNAKPFIF_03634 4.1e-170 whiA K May be required for sporulation
KNAKPFIF_03635 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KNAKPFIF_03636 5.7e-166 rapZ S Displays ATPase and GTPase activities
KNAKPFIF_03637 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KNAKPFIF_03638 2.8e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KNAKPFIF_03639 8.1e-98 usp CBM50 M protein conserved in bacteria
KNAKPFIF_03640 2.4e-278 S COG0457 FOG TPR repeat
KNAKPFIF_03641 0.0 msbA2 3.6.3.44 V ABC transporter
KNAKPFIF_03643 0.0
KNAKPFIF_03644 1.4e-74
KNAKPFIF_03645 2.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KNAKPFIF_03646 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KNAKPFIF_03647 1.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KNAKPFIF_03648 8.1e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KNAKPFIF_03649 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KNAKPFIF_03650 3.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KNAKPFIF_03651 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KNAKPFIF_03652 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KNAKPFIF_03653 4.5e-140 yvpB NU protein conserved in bacteria
KNAKPFIF_03654 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
KNAKPFIF_03655 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KNAKPFIF_03656 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KNAKPFIF_03657 4.5e-161 yvoD P COG0370 Fe2 transport system protein B
KNAKPFIF_03658 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KNAKPFIF_03659 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KNAKPFIF_03660 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KNAKPFIF_03661 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KNAKPFIF_03662 3.6e-134 yvoA K transcriptional
KNAKPFIF_03663 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KNAKPFIF_03664 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
KNAKPFIF_03665 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
KNAKPFIF_03666 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
KNAKPFIF_03667 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
KNAKPFIF_03668 2.7e-203 yvmA EGP Major facilitator Superfamily
KNAKPFIF_03669 1.2e-50 yvlD S Membrane
KNAKPFIF_03670 2.6e-26 pspB KT PspC domain
KNAKPFIF_03671 3.4e-168 yvlB S Putative adhesin
KNAKPFIF_03672 8e-49 yvlA
KNAKPFIF_03673 6.7e-34 yvkN
KNAKPFIF_03674 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNAKPFIF_03675 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KNAKPFIF_03676 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KNAKPFIF_03677 1.2e-30 csbA S protein conserved in bacteria
KNAKPFIF_03678 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KNAKPFIF_03679 7e-101 yvkB K Transcriptional regulator
KNAKPFIF_03680 9.6e-226 yvkA EGP Major facilitator Superfamily
KNAKPFIF_03681 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNAKPFIF_03682 5.3e-56 swrA S Swarming motility protein
KNAKPFIF_03683 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KNAKPFIF_03684 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KNAKPFIF_03685 2.7e-123 ftsE D cell division ATP-binding protein FtsE
KNAKPFIF_03686 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
KNAKPFIF_03687 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KNAKPFIF_03688 3.9e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KNAKPFIF_03689 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KNAKPFIF_03690 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KNAKPFIF_03691 4.6e-51
KNAKPFIF_03692 1.9e-08 fliT S bacterial-type flagellum organization
KNAKPFIF_03693 6.5e-69 fliS N flagellar protein FliS
KNAKPFIF_03694 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KNAKPFIF_03695 1.2e-55 flaG N flagellar protein FlaG
KNAKPFIF_03696 1.4e-122 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KNAKPFIF_03697 5.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KNAKPFIF_03698 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KNAKPFIF_03699 1.3e-49 yviE
KNAKPFIF_03700 1.3e-154 flgL N Belongs to the bacterial flagellin family
KNAKPFIF_03701 1.6e-264 flgK N flagellar hook-associated protein
KNAKPFIF_03702 2.4e-78 flgN NOU FlgN protein
KNAKPFIF_03703 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
KNAKPFIF_03704 7e-74 yvyF S flagellar protein
KNAKPFIF_03705 2.7e-129 comFC S Phosphoribosyl transferase domain
KNAKPFIF_03706 5.7e-46 comFB S Late competence development protein ComFB
KNAKPFIF_03707 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KNAKPFIF_03708 7.3e-155 degV S protein conserved in bacteria
KNAKPFIF_03709 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KNAKPFIF_03710 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KNAKPFIF_03711 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KNAKPFIF_03712 6e-163 yvhJ K Transcriptional regulator
KNAKPFIF_03713 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KNAKPFIF_03714 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KNAKPFIF_03715 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
KNAKPFIF_03716 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
KNAKPFIF_03717 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
KNAKPFIF_03718 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNAKPFIF_03719 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KNAKPFIF_03720 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KNAKPFIF_03721 2.7e-78 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KNAKPFIF_03722 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KNAKPFIF_03723 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KNAKPFIF_03724 6e-38
KNAKPFIF_03725 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KNAKPFIF_03726 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KNAKPFIF_03727 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KNAKPFIF_03728 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KNAKPFIF_03729 8.1e-257 ggaA M Glycosyltransferase like family 2
KNAKPFIF_03731 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KNAKPFIF_03732 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KNAKPFIF_03733 1.1e-150 tagG GM Transport permease protein
KNAKPFIF_03734 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KNAKPFIF_03735 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
KNAKPFIF_03736 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KNAKPFIF_03737 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KNAKPFIF_03738 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KNAKPFIF_03739 1.2e-260
KNAKPFIF_03740 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KNAKPFIF_03741 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KNAKPFIF_03742 3.5e-266 gerBA EG Spore germination protein
KNAKPFIF_03743 7.5e-200 gerBB E Spore germination protein
KNAKPFIF_03744 7.6e-216 gerAC S Spore germination protein
KNAKPFIF_03745 1.9e-248 ywtG EGP Major facilitator Superfamily
KNAKPFIF_03746 8.4e-171 ywtF K Transcriptional regulator
KNAKPFIF_03747 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KNAKPFIF_03748 7.7e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KNAKPFIF_03749 3.6e-21 ywtC
KNAKPFIF_03750 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KNAKPFIF_03751 8.6e-70 pgsC S biosynthesis protein
KNAKPFIF_03752 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KNAKPFIF_03753 3e-176 rbsR K transcriptional
KNAKPFIF_03754 1.3e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KNAKPFIF_03755 2.6e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KNAKPFIF_03756 5.2e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KNAKPFIF_03757 6e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
KNAKPFIF_03758 4.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KNAKPFIF_03759 7.3e-92 batE T Sh3 type 3 domain protein
KNAKPFIF_03760 8e-48 ywsA S Protein of unknown function (DUF3892)
KNAKPFIF_03761 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
KNAKPFIF_03762 4.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KNAKPFIF_03763 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KNAKPFIF_03764 2.5e-169 alsR K LysR substrate binding domain
KNAKPFIF_03765 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KNAKPFIF_03766 1.1e-124 ywrJ
KNAKPFIF_03767 2.6e-123 cotB
KNAKPFIF_03768 1.8e-206 cotH M Spore Coat
KNAKPFIF_03769 3.7e-12
KNAKPFIF_03770 5.3e-60 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KNAKPFIF_03771 5e-54 S Domain of unknown function (DUF4181)
KNAKPFIF_03772 9.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KNAKPFIF_03773 8e-82 ywrC K Transcriptional regulator
KNAKPFIF_03774 1.6e-103 ywrB P Chromate transporter
KNAKPFIF_03775 1.4e-87 ywrA P COG2059 Chromate transport protein ChrA
KNAKPFIF_03777 4.8e-99 ywqN S NAD(P)H-dependent
KNAKPFIF_03778 1.4e-161 K Transcriptional regulator
KNAKPFIF_03779 5.4e-131 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KNAKPFIF_03780 1.7e-52 S MORN repeat variant
KNAKPFIF_03781 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
KNAKPFIF_03782 1.3e-38 ywqI S Family of unknown function (DUF5344)
KNAKPFIF_03783 3.3e-15 S Domain of unknown function (DUF5082)
KNAKPFIF_03784 3.4e-154 ywqG S Domain of unknown function (DUF1963)
KNAKPFIF_03785 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KNAKPFIF_03786 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KNAKPFIF_03787 3.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KNAKPFIF_03788 2e-116 ywqC M biosynthesis protein
KNAKPFIF_03789 1.2e-17
KNAKPFIF_03790 1e-306 ywqB S SWIM zinc finger
KNAKPFIF_03791 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KNAKPFIF_03792 5.7e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KNAKPFIF_03793 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
KNAKPFIF_03794 2.2e-57 ssbB L Single-stranded DNA-binding protein
KNAKPFIF_03795 1.2e-29 ywpG
KNAKPFIF_03796 6.9e-66 ywpF S YwpF-like protein
KNAKPFIF_03797 5.2e-50 srtA 3.4.22.70 M Sortase family
KNAKPFIF_03798 2.1e-144 ywpD T Histidine kinase
KNAKPFIF_03799 1.1e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KNAKPFIF_03800 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KNAKPFIF_03801 7.5e-197 S aspartate phosphatase
KNAKPFIF_03802 2.6e-141 flhP N flagellar basal body
KNAKPFIF_03803 3.2e-123 flhO N flagellar basal body
KNAKPFIF_03804 3.5e-180 mbl D Rod shape-determining protein
KNAKPFIF_03805 3e-44 spoIIID K Stage III sporulation protein D
KNAKPFIF_03806 2.1e-70 ywoH K COG1846 Transcriptional regulators
KNAKPFIF_03807 3.9e-210 ywoG EGP Major facilitator Superfamily
KNAKPFIF_03808 9.8e-229 ywoF P Right handed beta helix region
KNAKPFIF_03809 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KNAKPFIF_03810 2.4e-240 ywoD EGP Major facilitator superfamily
KNAKPFIF_03811 3.4e-103 phzA Q Isochorismatase family
KNAKPFIF_03812 1.7e-76
KNAKPFIF_03813 1.3e-224 amt P Ammonium transporter
KNAKPFIF_03814 1.6e-58 nrgB K Belongs to the P(II) protein family
KNAKPFIF_03815 7.7e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KNAKPFIF_03816 5.6e-71 ywnJ S VanZ like family
KNAKPFIF_03817 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KNAKPFIF_03818 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KNAKPFIF_03819 1.3e-08 ywnC S Family of unknown function (DUF5362)
KNAKPFIF_03820 1.5e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
KNAKPFIF_03821 2.2e-70 ywnF S Family of unknown function (DUF5392)
KNAKPFIF_03822 4.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNAKPFIF_03823 2.1e-140 mta K transcriptional
KNAKPFIF_03824 2.6e-59 ywnC S Family of unknown function (DUF5362)
KNAKPFIF_03825 9.9e-112 ywnB S NAD(P)H-binding
KNAKPFIF_03826 1.7e-64 ywnA K Transcriptional regulator
KNAKPFIF_03827 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KNAKPFIF_03828 2.2e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KNAKPFIF_03829 1.8e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KNAKPFIF_03831 1.4e-10 csbD K CsbD-like
KNAKPFIF_03832 1.1e-83 ywmF S Peptidase M50
KNAKPFIF_03833 2.7e-104 S response regulator aspartate phosphatase
KNAKPFIF_03834 7.7e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KNAKPFIF_03835 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KNAKPFIF_03837 1.4e-119 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KNAKPFIF_03838 9.6e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KNAKPFIF_03839 7.5e-178 spoIID D Stage II sporulation protein D
KNAKPFIF_03840 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNAKPFIF_03841 9e-133 ywmB S TATA-box binding
KNAKPFIF_03842 1.3e-32 ywzB S membrane
KNAKPFIF_03843 1.4e-86 ywmA
KNAKPFIF_03844 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KNAKPFIF_03845 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KNAKPFIF_03846 1.9e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KNAKPFIF_03847 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KNAKPFIF_03848 1.5e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNAKPFIF_03849 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KNAKPFIF_03850 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KNAKPFIF_03851 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
KNAKPFIF_03852 2.5e-62 atpI S ATP synthase
KNAKPFIF_03853 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KNAKPFIF_03854 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KNAKPFIF_03855 7.2e-95 ywlG S Belongs to the UPF0340 family
KNAKPFIF_03856 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KNAKPFIF_03857 1.9e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KNAKPFIF_03858 4.9e-91 mntP P Probably functions as a manganese efflux pump
KNAKPFIF_03859 1.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KNAKPFIF_03860 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KNAKPFIF_03861 6.1e-112 spoIIR S stage II sporulation protein R
KNAKPFIF_03862 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
KNAKPFIF_03864 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KNAKPFIF_03865 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KNAKPFIF_03866 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNAKPFIF_03867 1.2e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KNAKPFIF_03868 8.6e-160 ywkB S Membrane transport protein
KNAKPFIF_03869 0.0 sfcA 1.1.1.38 C malic enzyme
KNAKPFIF_03870 7e-104 tdk 2.7.1.21 F thymidine kinase
KNAKPFIF_03871 1.1e-32 rpmE J Binds the 23S rRNA
KNAKPFIF_03872 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KNAKPFIF_03873 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KNAKPFIF_03874 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KNAKPFIF_03876 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KNAKPFIF_03877 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KNAKPFIF_03878 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
KNAKPFIF_03879 2.4e-92 ywjG S Domain of unknown function (DUF2529)
KNAKPFIF_03880 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KNAKPFIF_03881 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KNAKPFIF_03882 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KNAKPFIF_03883 0.0 fadF C COG0247 Fe-S oxidoreductase
KNAKPFIF_03884 1.1e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KNAKPFIF_03885 5.6e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KNAKPFIF_03886 1.1e-95 ywjB H RibD C-terminal domain
KNAKPFIF_03887 2.8e-271 ywjA V ABC transporter
KNAKPFIF_03888 8.3e-30 ywjA V ABC transporter
KNAKPFIF_03889 3.5e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KNAKPFIF_03890 9.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
KNAKPFIF_03891 3.6e-94 narJ 1.7.5.1 C nitrate reductase
KNAKPFIF_03892 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
KNAKPFIF_03893 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KNAKPFIF_03894 7e-86 arfM T cyclic nucleotide binding
KNAKPFIF_03895 1.7e-139 ywiC S YwiC-like protein
KNAKPFIF_03896 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KNAKPFIF_03897 1e-213 narK P COG2223 Nitrate nitrite transporter
KNAKPFIF_03898 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KNAKPFIF_03899 2.3e-72 ywiB S protein conserved in bacteria
KNAKPFIF_03900 1e-07 S Bacteriocin subtilosin A
KNAKPFIF_03901 4.9e-270 C Fe-S oxidoreductases
KNAKPFIF_03903 1.3e-131 cbiO V ABC transporter
KNAKPFIF_03904 2e-231 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KNAKPFIF_03905 1.4e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
KNAKPFIF_03906 5.2e-245 L Peptidase, M16
KNAKPFIF_03908 6.2e-244 ywhL CO amine dehydrogenase activity
KNAKPFIF_03909 1.1e-189 ywhK CO amine dehydrogenase activity
KNAKPFIF_03910 3.1e-79 S aspartate phosphatase
KNAKPFIF_03912 1.2e-65 ywhH S Aminoacyl-tRNA editing domain
KNAKPFIF_03913 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
KNAKPFIF_03914 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KNAKPFIF_03915 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KNAKPFIF_03916 5.2e-95 ywhD S YwhD family
KNAKPFIF_03917 5.1e-119 ywhC S Peptidase family M50
KNAKPFIF_03918 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KNAKPFIF_03919 3.3e-71 ywhA K Transcriptional regulator
KNAKPFIF_03920 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KNAKPFIF_03922 2.6e-242 mmr U Major Facilitator Superfamily
KNAKPFIF_03923 2.8e-79 yffB K Transcriptional regulator
KNAKPFIF_03924 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
KNAKPFIF_03925 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
KNAKPFIF_03926 3.1e-36 ywzC S Belongs to the UPF0741 family
KNAKPFIF_03927 1.6e-111 rsfA_1
KNAKPFIF_03928 5.2e-159 ywfM EG EamA-like transporter family
KNAKPFIF_03929 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KNAKPFIF_03930 9.2e-164 cysL K Transcriptional regulator
KNAKPFIF_03931 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KNAKPFIF_03932 1.1e-146 ywfI C May function as heme-dependent peroxidase
KNAKPFIF_03933 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
KNAKPFIF_03934 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
KNAKPFIF_03935 2.9e-210 bacE EGP Major facilitator Superfamily
KNAKPFIF_03936 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KNAKPFIF_03937 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_03938 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KNAKPFIF_03939 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KNAKPFIF_03940 4.6e-206 ywfA EGP Major facilitator Superfamily
KNAKPFIF_03941 4e-262 lysP E amino acid
KNAKPFIF_03942 0.0 rocB E arginine degradation protein
KNAKPFIF_03943 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KNAKPFIF_03944 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KNAKPFIF_03945 7.5e-77
KNAKPFIF_03946 7.8e-55 spsL 5.1.3.13 M Spore Coat
KNAKPFIF_03947 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KNAKPFIF_03948 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KNAKPFIF_03949 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KNAKPFIF_03950 1.7e-190 spsG M Spore Coat
KNAKPFIF_03951 9.7e-132 spsF M Spore Coat
KNAKPFIF_03952 3.2e-214 spsE 2.5.1.56 M acid synthase
KNAKPFIF_03953 4e-164 spsD 2.3.1.210 K Spore Coat
KNAKPFIF_03954 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
KNAKPFIF_03955 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
KNAKPFIF_03956 2.8e-145 spsA M Spore Coat
KNAKPFIF_03957 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KNAKPFIF_03958 4.3e-59 ywdK S small membrane protein
KNAKPFIF_03959 1.3e-238 ywdJ F Xanthine uracil
KNAKPFIF_03960 7.7e-49 ywdI S Family of unknown function (DUF5327)
KNAKPFIF_03961 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KNAKPFIF_03962 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KNAKPFIF_03963 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
KNAKPFIF_03965 1.4e-113 ywdD
KNAKPFIF_03966 1.3e-57 pex K Transcriptional regulator PadR-like family
KNAKPFIF_03967 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KNAKPFIF_03968 2e-28 ywdA
KNAKPFIF_03969 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
KNAKPFIF_03970 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KNAKPFIF_03971 1e-139 focA P Formate/nitrite transporter
KNAKPFIF_03972 2.4e-150 sacT K transcriptional antiterminator
KNAKPFIF_03974 0.0 vpr O Belongs to the peptidase S8 family
KNAKPFIF_03975 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNAKPFIF_03976 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KNAKPFIF_03977 2.9e-202 rodA D Belongs to the SEDS family
KNAKPFIF_03978 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
KNAKPFIF_03979 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KNAKPFIF_03980 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KNAKPFIF_03981 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KNAKPFIF_03982 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KNAKPFIF_03983 1e-35 ywzA S membrane
KNAKPFIF_03984 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KNAKPFIF_03985 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KNAKPFIF_03986 9.5e-60 gtcA S GtrA-like protein
KNAKPFIF_03987 2.2e-122 ywcC K transcriptional regulator
KNAKPFIF_03989 9.8e-49 ywcB S Protein of unknown function, DUF485
KNAKPFIF_03990 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KNAKPFIF_03991 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KNAKPFIF_03992 2.6e-225 ywbN P Dyp-type peroxidase family protein
KNAKPFIF_03993 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
KNAKPFIF_03994 4.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
KNAKPFIF_03995 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KNAKPFIF_03996 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KNAKPFIF_03997 4.3e-153 ywbI K Transcriptional regulator
KNAKPFIF_03998 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KNAKPFIF_03999 2.3e-111 ywbG M effector of murein hydrolase
KNAKPFIF_04000 7.3e-209 ywbF EGP Major facilitator Superfamily
KNAKPFIF_04001 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
KNAKPFIF_04002 1e-218 ywbD 2.1.1.191 J Methyltransferase
KNAKPFIF_04003 9.9e-67 ywbC 4.4.1.5 E glyoxalase
KNAKPFIF_04004 2e-126 ywbB S Protein of unknown function (DUF2711)
KNAKPFIF_04005 2.5e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNAKPFIF_04006 1.4e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
KNAKPFIF_04007 5.4e-240 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KNAKPFIF_04008 1.2e-152 sacY K transcriptional antiterminator
KNAKPFIF_04009 1.3e-167 gspA M General stress
KNAKPFIF_04010 4.2e-127 ywaF S Integral membrane protein
KNAKPFIF_04011 8.1e-88 ywaE K Transcriptional regulator
KNAKPFIF_04012 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KNAKPFIF_04013 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KNAKPFIF_04014 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
KNAKPFIF_04015 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KNAKPFIF_04016 5e-14 S D-Ala-teichoic acid biosynthesis protein
KNAKPFIF_04017 5.3e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_04018 1.2e-232 dltB M membrane protein involved in D-alanine export
KNAKPFIF_04019 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KNAKPFIF_04020 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KNAKPFIF_04021 8.6e-47 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_04022 7.8e-64 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_04023 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KNAKPFIF_04024 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KNAKPFIF_04025 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KNAKPFIF_04026 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KNAKPFIF_04027 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KNAKPFIF_04028 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KNAKPFIF_04029 9.3e-19 yxzF
KNAKPFIF_04030 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KNAKPFIF_04031 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KNAKPFIF_04032 2.6e-214 yxlH EGP Major facilitator Superfamily
KNAKPFIF_04033 1.3e-137 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KNAKPFIF_04034 9.7e-166 yxlF V ABC transporter, ATP-binding protein
KNAKPFIF_04035 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
KNAKPFIF_04036 2.2e-28
KNAKPFIF_04037 5.6e-47 yxlC S Family of unknown function (DUF5345)
KNAKPFIF_04038 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
KNAKPFIF_04039 5e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KNAKPFIF_04040 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KNAKPFIF_04041 0.0 cydD V ATP-binding protein
KNAKPFIF_04042 0.0 cydD V ATP-binding
KNAKPFIF_04043 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KNAKPFIF_04044 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
KNAKPFIF_04045 1.5e-229 cimH C COG3493 Na citrate symporter
KNAKPFIF_04046 0.0 3.4.24.84 O Peptidase family M48
KNAKPFIF_04048 3e-156 yxkH G Polysaccharide deacetylase
KNAKPFIF_04049 5.9e-205 msmK P Belongs to the ABC transporter superfamily
KNAKPFIF_04050 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
KNAKPFIF_04051 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KNAKPFIF_04052 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KNAKPFIF_04053 4.1e-73 yxkC S Domain of unknown function (DUF4352)
KNAKPFIF_04054 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KNAKPFIF_04055 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
KNAKPFIF_04056 1.9e-166 yxjO K LysR substrate binding domain
KNAKPFIF_04057 2.4e-78 S Protein of unknown function (DUF1453)
KNAKPFIF_04058 1.5e-193 yxjM T Signal transduction histidine kinase
KNAKPFIF_04059 8.9e-116 K helix_turn_helix, Lux Regulon
KNAKPFIF_04060 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KNAKPFIF_04063 1e-87 yxjI S LURP-one-related
KNAKPFIF_04064 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
KNAKPFIF_04065 3.1e-217 yxjG 2.1.1.14 E Methionine synthase
KNAKPFIF_04066 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KNAKPFIF_04067 1.7e-114 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KNAKPFIF_04068 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KNAKPFIF_04069 2.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
KNAKPFIF_04070 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
KNAKPFIF_04071 2.1e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNAKPFIF_04072 1.5e-102 T Domain of unknown function (DUF4163)
KNAKPFIF_04073 3e-47 yxiS
KNAKPFIF_04074 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KNAKPFIF_04075 6.6e-224 citH C Citrate transporter
KNAKPFIF_04076 3.6e-142 exoK GH16 M licheninase activity
KNAKPFIF_04077 8.3e-151 licT K transcriptional antiterminator
KNAKPFIF_04078 6.2e-112
KNAKPFIF_04079 7.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
KNAKPFIF_04080 2.5e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KNAKPFIF_04081 8.6e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
KNAKPFIF_04084 3.5e-43 yxiJ S YxiJ-like protein
KNAKPFIF_04087 3.2e-32
KNAKPFIF_04088 3.5e-93 yxiI S Protein of unknown function (DUF2716)
KNAKPFIF_04089 9.4e-142
KNAKPFIF_04090 8.3e-13 yxiG
KNAKPFIF_04091 5.3e-16 yxiG
KNAKPFIF_04092 1.9e-38 S Protein of unknown function (DUF2750)
KNAKPFIF_04093 3.4e-52 yxxG
KNAKPFIF_04094 4.3e-68 yxiG
KNAKPFIF_04095 4.1e-44
KNAKPFIF_04096 4.9e-76
KNAKPFIF_04097 4.7e-94 S Protein of unknown function (DUF4240)
KNAKPFIF_04098 4.5e-141
KNAKPFIF_04100 7e-55
KNAKPFIF_04101 1.6e-80 wapA M COG3209 Rhs family protein
KNAKPFIF_04102 4.1e-14 yxiJ S YxiJ-like protein
KNAKPFIF_04103 0.0 wapA M COG3209 Rhs family protein
KNAKPFIF_04104 1.8e-162 yxxF EG EamA-like transporter family
KNAKPFIF_04105 1.2e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KNAKPFIF_04106 2.1e-121 1.14.11.45 E 2OG-Fe dioxygenase
KNAKPFIF_04107 1.1e-72 yxiE T Belongs to the universal stress protein A family
KNAKPFIF_04108 2.9e-173 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KNAKPFIF_04109 6.8e-93 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KNAKPFIF_04110 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KNAKPFIF_04111 3.6e-51
KNAKPFIF_04112 2.2e-78 S SMI1 / KNR4 family
KNAKPFIF_04113 0.0 S nuclease activity
KNAKPFIF_04114 3.6e-39 yxiC S Family of unknown function (DUF5344)
KNAKPFIF_04115 2.1e-21 S Domain of unknown function (DUF5082)
KNAKPFIF_04116 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KNAKPFIF_04117 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KNAKPFIF_04118 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
KNAKPFIF_04119 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KNAKPFIF_04120 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KNAKPFIF_04121 1.3e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KNAKPFIF_04122 6.1e-252 lysP E amino acid
KNAKPFIF_04123 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KNAKPFIF_04124 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KNAKPFIF_04125 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KNAKPFIF_04126 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KNAKPFIF_04127 3e-153 yxxB S Domain of Unknown Function (DUF1206)
KNAKPFIF_04128 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
KNAKPFIF_04129 2e-255 yxeQ S MmgE/PrpD family
KNAKPFIF_04130 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
KNAKPFIF_04131 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KNAKPFIF_04132 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
KNAKPFIF_04133 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
KNAKPFIF_04134 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KNAKPFIF_04135 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KNAKPFIF_04137 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KNAKPFIF_04138 6.2e-151 yidA S hydrolases of the HAD superfamily
KNAKPFIF_04141 1.3e-20 yxeE
KNAKPFIF_04142 1.9e-16 yxeD
KNAKPFIF_04143 7.2e-68
KNAKPFIF_04144 2.3e-176 fhuD P ABC transporter
KNAKPFIF_04145 1.5e-58 yxeA S Protein of unknown function (DUF1093)
KNAKPFIF_04146 6.9e-306 yxdM V ABC transporter (permease)
KNAKPFIF_04147 3.4e-68 yxdL V ABC transporter, ATP-binding protein
KNAKPFIF_04148 1.3e-51 yxdL V ABC transporter, ATP-binding protein
KNAKPFIF_04149 7.6e-180 T PhoQ Sensor
KNAKPFIF_04150 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_04151 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KNAKPFIF_04152 3.3e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KNAKPFIF_04153 3.3e-166 iolH G Xylose isomerase-like TIM barrel
KNAKPFIF_04154 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KNAKPFIF_04155 4e-232 iolF EGP Major facilitator Superfamily
KNAKPFIF_04156 3.6e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KNAKPFIF_04157 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KNAKPFIF_04158 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KNAKPFIF_04159 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KNAKPFIF_04160 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KNAKPFIF_04161 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
KNAKPFIF_04162 3.7e-176 iolS C Aldo keto reductase
KNAKPFIF_04164 8.3e-48 yxcD S Protein of unknown function (DUF2653)
KNAKPFIF_04165 2.3e-246 csbC EGP Major facilitator Superfamily
KNAKPFIF_04166 0.0 htpG O Molecular chaperone. Has ATPase activity
KNAKPFIF_04168 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
KNAKPFIF_04169 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
KNAKPFIF_04170 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KNAKPFIF_04171 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
KNAKPFIF_04172 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
KNAKPFIF_04173 3.3e-127 yxbB Q Met-10+ like-protein
KNAKPFIF_04174 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
KNAKPFIF_04175 1.1e-86 yxnB
KNAKPFIF_04176 0.0 asnB 6.3.5.4 E Asparagine synthase
KNAKPFIF_04177 7.6e-214 yxaM U MFS_1 like family
KNAKPFIF_04178 6.8e-93 S PQQ-like domain
KNAKPFIF_04179 3.5e-65 S Family of unknown function (DUF5391)
KNAKPFIF_04180 1.1e-75 yxaI S membrane protein domain
KNAKPFIF_04181 1.4e-228 P Protein of unknown function (DUF418)
KNAKPFIF_04182 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
KNAKPFIF_04183 7.1e-101 yxaF K Transcriptional regulator
KNAKPFIF_04184 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KNAKPFIF_04185 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
KNAKPFIF_04186 5.2e-50 S LrgA family
KNAKPFIF_04187 2.6e-118 yxaC M effector of murein hydrolase
KNAKPFIF_04188 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
KNAKPFIF_04189 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KNAKPFIF_04190 7.3e-127 gntR K transcriptional
KNAKPFIF_04191 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KNAKPFIF_04192 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
KNAKPFIF_04193 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KNAKPFIF_04194 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KNAKPFIF_04195 3.8e-287 ahpF O Alkyl hydroperoxide reductase
KNAKPFIF_04196 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KNAKPFIF_04197 2.5e-19 bglF G phosphotransferase system
KNAKPFIF_04198 1.3e-128 yydK K Transcriptional regulator
KNAKPFIF_04199 7.6e-13
KNAKPFIF_04200 3.3e-119 S ABC-2 family transporter protein
KNAKPFIF_04201 1.8e-110 prrC P ABC transporter
KNAKPFIF_04202 8.4e-134 yydH O Peptidase M50
KNAKPFIF_04203 7.7e-185 S Radical SAM superfamily
KNAKPFIF_04204 8e-12
KNAKPFIF_04205 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KNAKPFIF_04206 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
KNAKPFIF_04207 3.5e-65
KNAKPFIF_04208 7.3e-280 S Calcineurin-like phosphoesterase
KNAKPFIF_04209 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KNAKPFIF_04210 4.2e-09 S YyzF-like protein
KNAKPFIF_04211 2.2e-67
KNAKPFIF_04212 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KNAKPFIF_04214 1.7e-30 yycQ S Protein of unknown function (DUF2651)
KNAKPFIF_04215 3.5e-200 yycP
KNAKPFIF_04216 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KNAKPFIF_04217 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
KNAKPFIF_04218 5e-188 S aspartate phosphatase
KNAKPFIF_04220 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KNAKPFIF_04221 9.7e-261 rocE E amino acid
KNAKPFIF_04222 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KNAKPFIF_04223 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KNAKPFIF_04224 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KNAKPFIF_04225 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KNAKPFIF_04226 7.3e-155 yycI S protein conserved in bacteria
KNAKPFIF_04227 3.1e-259 yycH S protein conserved in bacteria
KNAKPFIF_04228 0.0 vicK 2.7.13.3 T Histidine kinase
KNAKPFIF_04229 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KNAKPFIF_04234 9.6e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KNAKPFIF_04235 1.9e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNAKPFIF_04236 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KNAKPFIF_04237 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KNAKPFIF_04239 1.9e-15 yycC K YycC-like protein
KNAKPFIF_04240 7.9e-219 yeaN P COG2807 Cyanate permease
KNAKPFIF_04241 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KNAKPFIF_04242 2.2e-73 rplI J binds to the 23S rRNA
KNAKPFIF_04243 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KNAKPFIF_04244 8.3e-160 yybS S membrane
KNAKPFIF_04246 4e-14 cotF M Spore coat protein
KNAKPFIF_04247 1.7e-51 cotF M Spore coat protein
KNAKPFIF_04248 1.7e-66 ydeP3 K Transcriptional regulator
KNAKPFIF_04249 4.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KNAKPFIF_04250 1.6e-60
KNAKPFIF_04252 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
KNAKPFIF_04253 1.1e-109 K TipAS antibiotic-recognition domain
KNAKPFIF_04254 4.8e-124
KNAKPFIF_04255 9.5e-65 yybH S SnoaL-like domain
KNAKPFIF_04256 9.6e-123 yybG S Pentapeptide repeat-containing protein
KNAKPFIF_04257 2.2e-216 ynfM EGP Major facilitator Superfamily
KNAKPFIF_04258 2.1e-165 yybE K Transcriptional regulator
KNAKPFIF_04259 2e-79 yjcF S Acetyltransferase (GNAT) domain
KNAKPFIF_04260 2.7e-77 yybC
KNAKPFIF_04261 3e-127 S Metallo-beta-lactamase superfamily
KNAKPFIF_04262 5.6e-77 yybA 2.3.1.57 K transcriptional
KNAKPFIF_04263 2.4e-72 yjcF S Acetyltransferase (GNAT) domain
KNAKPFIF_04264 7.2e-96 yyaS S Membrane
KNAKPFIF_04265 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
KNAKPFIF_04266 1.3e-65 yyaQ S YjbR
KNAKPFIF_04267 6.7e-104 yyaP 1.5.1.3 H RibD C-terminal domain
KNAKPFIF_04268 3.6e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KNAKPFIF_04269 2e-82 yosT L Bacterial transcription activator, effector binding domain
KNAKPFIF_04270 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KNAKPFIF_04271 8e-168 yyaK S CAAX protease self-immunity
KNAKPFIF_04272 1.8e-243 EGP Major facilitator superfamily
KNAKPFIF_04273 1.6e-61 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KNAKPFIF_04274 1.2e-40 2.7.7.73, 2.7.7.80 H ThiF family
KNAKPFIF_04275 3.5e-34 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KNAKPFIF_04276 1.4e-40 yxaM EGP PFAM Major Facilitator Superfamily
KNAKPFIF_04277 4.2e-61 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KNAKPFIF_04278 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
KNAKPFIF_04279 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KNAKPFIF_04280 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KNAKPFIF_04281 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KNAKPFIF_04282 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KNAKPFIF_04283 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KNAKPFIF_04284 2.3e-33 yyzM S protein conserved in bacteria
KNAKPFIF_04285 8.1e-177 yyaD S Membrane
KNAKPFIF_04286 1.6e-111 yyaC S Sporulation protein YyaC
KNAKPFIF_04287 2.1e-149 spo0J K Belongs to the ParB family
KNAKPFIF_04288 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
KNAKPFIF_04289 1.5e-74 S Bacterial PH domain
KNAKPFIF_04290 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KNAKPFIF_04291 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KNAKPFIF_04292 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KNAKPFIF_04293 8.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KNAKPFIF_04294 6.5e-108 jag S single-stranded nucleic acid binding R3H
KNAKPFIF_04295 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KNAKPFIF_04296 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)