ORF_ID e_value Gene_name EC_number CAZy COGs Description
LOPFHFCG_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LOPFHFCG_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LOPFHFCG_00003 2.4e-33 yaaA S S4 domain
LOPFHFCG_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LOPFHFCG_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
LOPFHFCG_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOPFHFCG_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LOPFHFCG_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_00011 2.7e-182 yaaC S YaaC-like Protein
LOPFHFCG_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LOPFHFCG_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LOPFHFCG_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LOPFHFCG_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LOPFHFCG_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LOPFHFCG_00017 1.3e-09
LOPFHFCG_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
LOPFHFCG_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
LOPFHFCG_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
LOPFHFCG_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
LOPFHFCG_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LOPFHFCG_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOPFHFCG_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LOPFHFCG_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LOPFHFCG_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
LOPFHFCG_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
LOPFHFCG_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
LOPFHFCG_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LOPFHFCG_00033 4.5e-203 yaaN P Belongs to the TelA family
LOPFHFCG_00034 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LOPFHFCG_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LOPFHFCG_00036 2.2e-54 yaaQ S protein conserved in bacteria
LOPFHFCG_00037 1.5e-71 yaaR S protein conserved in bacteria
LOPFHFCG_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
LOPFHFCG_00039 6.1e-146 yaaT S stage 0 sporulation protein
LOPFHFCG_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
LOPFHFCG_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
LOPFHFCG_00042 1.5e-49 yazA L endonuclease containing a URI domain
LOPFHFCG_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LOPFHFCG_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
LOPFHFCG_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LOPFHFCG_00046 2e-143 tatD L hydrolase, TatD
LOPFHFCG_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
LOPFHFCG_00048 9.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LOPFHFCG_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LOPFHFCG_00050 1.6e-136 yabG S peptidase
LOPFHFCG_00051 7.8e-39 veg S protein conserved in bacteria
LOPFHFCG_00052 8.3e-27 sspF S DNA topological change
LOPFHFCG_00053 1.6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LOPFHFCG_00054 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LOPFHFCG_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LOPFHFCG_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LOPFHFCG_00057 7.3e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LOPFHFCG_00058 2.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LOPFHFCG_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LOPFHFCG_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LOPFHFCG_00061 2.4e-39 yabK S Peptide ABC transporter permease
LOPFHFCG_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LOPFHFCG_00063 1.5e-92 spoVT K stage V sporulation protein
LOPFHFCG_00064 3.8e-285 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOPFHFCG_00065 5.6e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LOPFHFCG_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LOPFHFCG_00067 1.5e-49 yabP S Sporulation protein YabP
LOPFHFCG_00068 2.5e-107 yabQ S spore cortex biosynthesis protein
LOPFHFCG_00069 1.1e-44 divIC D Septum formation initiator
LOPFHFCG_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
LOPFHFCG_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
LOPFHFCG_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
LOPFHFCG_00075 2.9e-182 KLT serine threonine protein kinase
LOPFHFCG_00076 2.5e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LOPFHFCG_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LOPFHFCG_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LOPFHFCG_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LOPFHFCG_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LOPFHFCG_00081 1.7e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
LOPFHFCG_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LOPFHFCG_00083 1.8e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LOPFHFCG_00084 1.6e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
LOPFHFCG_00085 6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
LOPFHFCG_00086 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LOPFHFCG_00087 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LOPFHFCG_00088 3.9e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LOPFHFCG_00089 4.1e-30 yazB K transcriptional
LOPFHFCG_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOPFHFCG_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LOPFHFCG_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_00093 2.9e-76 ctsR K Belongs to the CtsR family
LOPFHFCG_00094 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
LOPFHFCG_00095 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LOPFHFCG_00096 0.0 clpC O Belongs to the ClpA ClpB family
LOPFHFCG_00097 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LOPFHFCG_00098 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LOPFHFCG_00099 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
LOPFHFCG_00100 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LOPFHFCG_00101 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LOPFHFCG_00102 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LOPFHFCG_00103 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
LOPFHFCG_00104 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LOPFHFCG_00105 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LOPFHFCG_00106 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOPFHFCG_00107 1.2e-88 yacP S RNA-binding protein containing a PIN domain
LOPFHFCG_00108 1.5e-115 sigH K Belongs to the sigma-70 factor family
LOPFHFCG_00109 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LOPFHFCG_00110 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
LOPFHFCG_00111 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LOPFHFCG_00112 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LOPFHFCG_00113 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LOPFHFCG_00114 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LOPFHFCG_00115 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
LOPFHFCG_00116 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOPFHFCG_00117 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOPFHFCG_00118 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
LOPFHFCG_00119 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LOPFHFCG_00120 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LOPFHFCG_00121 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LOPFHFCG_00122 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LOPFHFCG_00123 2.4e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
LOPFHFCG_00124 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LOPFHFCG_00125 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LOPFHFCG_00126 3e-105 rplD J Forms part of the polypeptide exit tunnel
LOPFHFCG_00127 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LOPFHFCG_00128 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LOPFHFCG_00129 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LOPFHFCG_00130 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LOPFHFCG_00131 6.8e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LOPFHFCG_00132 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LOPFHFCG_00133 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LOPFHFCG_00134 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LOPFHFCG_00135 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LOPFHFCG_00136 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LOPFHFCG_00137 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LOPFHFCG_00138 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LOPFHFCG_00139 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LOPFHFCG_00140 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LOPFHFCG_00141 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LOPFHFCG_00142 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LOPFHFCG_00143 1.9e-23 rpmD J Ribosomal protein L30
LOPFHFCG_00144 1.8e-72 rplO J binds to the 23S rRNA
LOPFHFCG_00145 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LOPFHFCG_00146 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LOPFHFCG_00147 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
LOPFHFCG_00148 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LOPFHFCG_00149 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LOPFHFCG_00150 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LOPFHFCG_00151 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LOPFHFCG_00152 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LOPFHFCG_00153 3.6e-58 rplQ J Ribosomal protein L17
LOPFHFCG_00154 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOPFHFCG_00155 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOPFHFCG_00156 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LOPFHFCG_00157 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LOPFHFCG_00158 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LOPFHFCG_00159 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LOPFHFCG_00160 1.5e-143 ybaJ Q Methyltransferase domain
LOPFHFCG_00161 9.7e-66 ybaK S Protein of unknown function (DUF2521)
LOPFHFCG_00162 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOPFHFCG_00163 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LOPFHFCG_00164 1.2e-84 gerD
LOPFHFCG_00165 3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
LOPFHFCG_00166 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
LOPFHFCG_00167 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_00170 2e-08
LOPFHFCG_00174 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_00175 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_00176 1.3e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
LOPFHFCG_00178 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
LOPFHFCG_00179 7e-141 ybbA S Putative esterase
LOPFHFCG_00180 9.6e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_00181 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_00182 4e-165 feuA P Iron-uptake system-binding protein
LOPFHFCG_00183 1.2e-302 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
LOPFHFCG_00184 7.8e-238 ybbC 3.2.1.52 S protein conserved in bacteria
LOPFHFCG_00185 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
LOPFHFCG_00186 3.2e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
LOPFHFCG_00187 2.2e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOPFHFCG_00188 6.9e-148 ybbH K transcriptional
LOPFHFCG_00189 8.8e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LOPFHFCG_00190 1.9e-86 ybbJ J acetyltransferase
LOPFHFCG_00191 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
LOPFHFCG_00197 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_00198 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LOPFHFCG_00199 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LOPFHFCG_00200 4.6e-221 ybbR S protein conserved in bacteria
LOPFHFCG_00201 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LOPFHFCG_00202 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LOPFHFCG_00203 2.6e-42 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LOPFHFCG_00204 3.6e-99 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LOPFHFCG_00205 9.8e-120 adaA 3.2.2.21 K Transcriptional regulator
LOPFHFCG_00206 1.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LOPFHFCG_00207 2.1e-219 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LOPFHFCG_00208 1.6e-81 S KNTase C-terminal domain
LOPFHFCG_00209 0.0 ybcC S Belongs to the UPF0753 family
LOPFHFCG_00210 6.5e-93 can 4.2.1.1 P carbonic anhydrase
LOPFHFCG_00212 8.7e-47
LOPFHFCG_00213 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
LOPFHFCG_00214 1.5e-50 T Transcriptional regulatory protein, C terminal
LOPFHFCG_00215 5.9e-172 T His Kinase A (phospho-acceptor) domain
LOPFHFCG_00217 6.7e-139 KLT Protein tyrosine kinase
LOPFHFCG_00218 8.5e-151 ybdN
LOPFHFCG_00219 1.5e-214 ybdO S Domain of unknown function (DUF4885)
LOPFHFCG_00220 5.8e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_00221 1.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
LOPFHFCG_00222 4.9e-30 ybxH S Family of unknown function (DUF5370)
LOPFHFCG_00223 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
LOPFHFCG_00224 1.3e-243 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
LOPFHFCG_00225 1.6e-27 ybyB
LOPFHFCG_00226 5.2e-290 ybeC E amino acid
LOPFHFCG_00227 1.3e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LOPFHFCG_00228 7.3e-258 glpT G -transporter
LOPFHFCG_00229 8.5e-35 S Protein of unknown function (DUF2651)
LOPFHFCG_00230 2.2e-152 ybfA 3.4.15.5 K FR47-like protein
LOPFHFCG_00231 1.7e-143 ybfB G COG0477 Permeases of the major facilitator superfamily
LOPFHFCG_00232 2.7e-46 ybfB G COG0477 Permeases of the major facilitator superfamily
LOPFHFCG_00235 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
LOPFHFCG_00236 1.5e-161 ybfH EG EamA-like transporter family
LOPFHFCG_00237 2.3e-145 msmR K AraC-like ligand binding domain
LOPFHFCG_00238 2.8e-33 K sigma factor activity
LOPFHFCG_00239 9e-21 xhlB S SPP1 phage holin
LOPFHFCG_00240 2e-164 2.7.1.50, 3.5.2.6 GH19 M Lysin motif
LOPFHFCG_00241 3.9e-57
LOPFHFCG_00242 6.8e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LOPFHFCG_00243 1.3e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
LOPFHFCG_00245 2e-166 S Alpha/beta hydrolase family
LOPFHFCG_00246 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LOPFHFCG_00247 2.7e-85 ybfM S SNARE associated Golgi protein
LOPFHFCG_00248 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LOPFHFCG_00249 4.6e-45 ybfN
LOPFHFCG_00250 3.4e-255 S Erythromycin esterase
LOPFHFCG_00251 6.7e-167 ybfP K Transcriptional regulator
LOPFHFCG_00252 3.9e-192 yceA S Belongs to the UPF0176 family
LOPFHFCG_00253 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOPFHFCG_00254 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOPFHFCG_00255 1.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LOPFHFCG_00256 4.9e-128 K UTRA
LOPFHFCG_00258 1.3e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LOPFHFCG_00259 2.8e-260 mmuP E amino acid
LOPFHFCG_00260 4.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
LOPFHFCG_00261 1.4e-30 agcS E Sodium alanine symporter
LOPFHFCG_00262 9.4e-212 agcS E Sodium alanine symporter
LOPFHFCG_00263 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
LOPFHFCG_00264 9.4e-229 phoQ 2.7.13.3 T Histidine kinase
LOPFHFCG_00265 5.8e-169 glnL T Regulator
LOPFHFCG_00266 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
LOPFHFCG_00267 1.9e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOPFHFCG_00268 2.7e-255 gudP G COG0477 Permeases of the major facilitator superfamily
LOPFHFCG_00269 9.4e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LOPFHFCG_00270 2.1e-123 ycbG K FCD
LOPFHFCG_00271 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
LOPFHFCG_00272 1.2e-174 ycbJ S Macrolide 2'-phosphotransferase
LOPFHFCG_00273 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
LOPFHFCG_00274 1.9e-167 eamA1 EG spore germination
LOPFHFCG_00275 3.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_00276 5.4e-167 T PhoQ Sensor
LOPFHFCG_00277 1.2e-166 ycbN V ABC transporter, ATP-binding protein
LOPFHFCG_00278 2.1e-115 S ABC-2 family transporter protein
LOPFHFCG_00279 4.1e-52 ycbP S Protein of unknown function (DUF2512)
LOPFHFCG_00280 1.3e-78 sleB 3.5.1.28 M Cell wall
LOPFHFCG_00281 3.6e-134 ycbR T vWA found in TerF C terminus
LOPFHFCG_00282 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
LOPFHFCG_00283 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LOPFHFCG_00284 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LOPFHFCG_00285 5.9e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LOPFHFCG_00286 6.2e-202 ycbU E Selenocysteine lyase
LOPFHFCG_00287 5.3e-230 lmrB EGP the major facilitator superfamily
LOPFHFCG_00288 1.6e-100 yxaF K Transcriptional regulator
LOPFHFCG_00289 1.5e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LOPFHFCG_00290 7.3e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LOPFHFCG_00291 2e-59 S RDD family
LOPFHFCG_00292 3.1e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
LOPFHFCG_00293 9.1e-114 2.7.13.3 T GHKL domain
LOPFHFCG_00294 2.1e-34 2.7.13.3 T GHKL domain
LOPFHFCG_00295 2.3e-125 lytR_2 T LytTr DNA-binding domain
LOPFHFCG_00296 5e-60 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
LOPFHFCG_00297 5e-60 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
LOPFHFCG_00298 4.2e-201 natB CP ABC-2 family transporter protein
LOPFHFCG_00299 5e-173 yccK C Aldo keto reductase
LOPFHFCG_00300 1.1e-170 ycdA S Domain of unknown function (DUF5105)
LOPFHFCG_00301 2.1e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_00302 1.4e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_00303 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
LOPFHFCG_00304 2.2e-122 S response regulator aspartate phosphatase
LOPFHFCG_00305 9.6e-36 S response regulator aspartate phosphatase
LOPFHFCG_00306 3.7e-137 IQ Enoyl-(Acyl carrier protein) reductase
LOPFHFCG_00307 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LOPFHFCG_00308 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
LOPFHFCG_00309 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LOPFHFCG_00310 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LOPFHFCG_00311 6.1e-85 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_00312 4.7e-64 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_00313 7.4e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
LOPFHFCG_00314 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
LOPFHFCG_00315 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
LOPFHFCG_00316 1.4e-136 terC P Protein of unknown function (DUF475)
LOPFHFCG_00317 0.0 yceG S Putative component of 'biosynthetic module'
LOPFHFCG_00318 2e-192 yceH P Belongs to the TelA family
LOPFHFCG_00319 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
LOPFHFCG_00320 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
LOPFHFCG_00321 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
LOPFHFCG_00322 2.5e-228 proV 3.6.3.32 E glycine betaine
LOPFHFCG_00323 1.3e-127 opuAB P glycine betaine
LOPFHFCG_00324 4.5e-163 opuAC E glycine betaine
LOPFHFCG_00325 1.5e-214 amhX S amidohydrolase
LOPFHFCG_00326 1.4e-254 ycgA S Membrane
LOPFHFCG_00327 1.2e-80 ycgB
LOPFHFCG_00328 3.1e-270 amyE 3.2.1.1 GH13 G alpha-amylase
LOPFHFCG_00329 9.2e-98 amyE 3.2.1.1 GH13 G alpha-amylase
LOPFHFCG_00330 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LOPFHFCG_00331 1.5e-66 lctP C L-lactate permease
LOPFHFCG_00332 1e-210 lctP C L-lactate permease
LOPFHFCG_00333 1.4e-149 yqcI S YqcI/YcgG family
LOPFHFCG_00334 2.4e-76 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_00335 2.3e-90 ycgI S Domain of unknown function (DUF1989)
LOPFHFCG_00336 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LOPFHFCG_00337 9.5e-109 tmrB S AAA domain
LOPFHFCG_00338 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LOPFHFCG_00339 4e-112 L Integrase core domain
LOPFHFCG_00340 6e-44 tnpIS3 L Transposase
LOPFHFCG_00341 6.4e-142 yafE Q ubiE/COQ5 methyltransferase family
LOPFHFCG_00342 9.6e-175 oxyR3 K LysR substrate binding domain
LOPFHFCG_00343 1.2e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LOPFHFCG_00344 1.4e-144 ycgL S Predicted nucleotidyltransferase
LOPFHFCG_00345 5.1e-170 ycgM E Proline dehydrogenase
LOPFHFCG_00346 2.1e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LOPFHFCG_00347 1.2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOPFHFCG_00348 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
LOPFHFCG_00349 2.6e-147 ycgQ S membrane
LOPFHFCG_00350 1.2e-139 ycgR S permeases
LOPFHFCG_00351 3.4e-149 I alpha/beta hydrolase fold
LOPFHFCG_00352 1.9e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LOPFHFCG_00353 1e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LOPFHFCG_00354 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
LOPFHFCG_00355 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LOPFHFCG_00356 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOPFHFCG_00357 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
LOPFHFCG_00358 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
LOPFHFCG_00359 1e-117 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
LOPFHFCG_00360 1.5e-67 yciB M ErfK YbiS YcfS YnhG
LOPFHFCG_00361 3.6e-112 yciC S GTPases (G3E family)
LOPFHFCG_00362 1.8e-98 yciC S GTPases (G3E family)
LOPFHFCG_00363 5.1e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
LOPFHFCG_00364 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
LOPFHFCG_00367 1e-73 yckC S membrane
LOPFHFCG_00368 1.9e-50 yckD S Protein of unknown function (DUF2680)
LOPFHFCG_00369 5.3e-45 K MarR family
LOPFHFCG_00370 3.4e-20
LOPFHFCG_00371 5.1e-89 S AAA domain
LOPFHFCG_00372 3.7e-21 S AAA domain
LOPFHFCG_00373 9.8e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOPFHFCG_00374 5e-69 nin S Competence protein J (ComJ)
LOPFHFCG_00375 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
LOPFHFCG_00376 9.3e-57 tlpC 2.7.13.3 NT chemotaxis protein
LOPFHFCG_00377 7.8e-115 tlpC 2.7.13.3 NT chemotaxis protein
LOPFHFCG_00378 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
LOPFHFCG_00379 1.8e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
LOPFHFCG_00380 1.3e-63 hxlR K transcriptional
LOPFHFCG_00381 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_00382 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_00383 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
LOPFHFCG_00384 5.7e-140 srfAD Q thioesterase
LOPFHFCG_00385 3.1e-223 EGP Major Facilitator Superfamily
LOPFHFCG_00386 2.1e-89 S YcxB-like protein
LOPFHFCG_00387 1.3e-160 ycxC EG EamA-like transporter family
LOPFHFCG_00388 6.2e-249 ycxD K GntR family transcriptional regulator
LOPFHFCG_00389 5e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
LOPFHFCG_00390 4.4e-115 yczE S membrane
LOPFHFCG_00391 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LOPFHFCG_00392 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
LOPFHFCG_00393 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LOPFHFCG_00394 4.9e-162 bsdA K LysR substrate binding domain
LOPFHFCG_00395 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LOPFHFCG_00396 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LOPFHFCG_00397 4e-39 bsdD 4.1.1.61 S response to toxic substance
LOPFHFCG_00398 1.1e-83 yclD
LOPFHFCG_00399 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
LOPFHFCG_00400 1.5e-267 dtpT E amino acid peptide transporter
LOPFHFCG_00401 2.9e-310 yclG M Pectate lyase superfamily protein
LOPFHFCG_00403 6.8e-282 gerKA EG Spore germination protein
LOPFHFCG_00404 1.3e-232 gerKC S spore germination
LOPFHFCG_00405 9.9e-200 gerKB F Spore germination protein
LOPFHFCG_00406 3.9e-122 yclH P ABC transporter
LOPFHFCG_00407 1.7e-204 yclI V ABC transporter (permease) YclI
LOPFHFCG_00408 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_00409 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
LOPFHFCG_00410 5.2e-71 S aspartate phosphatase
LOPFHFCG_00414 1.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
LOPFHFCG_00415 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_00416 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_00417 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LOPFHFCG_00418 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
LOPFHFCG_00419 1.4e-251 ycnB EGP Major facilitator Superfamily
LOPFHFCG_00420 6.5e-154 ycnC K Transcriptional regulator
LOPFHFCG_00421 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
LOPFHFCG_00422 1.6e-45 ycnE S Monooxygenase
LOPFHFCG_00423 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
LOPFHFCG_00424 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOPFHFCG_00425 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LOPFHFCG_00426 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOPFHFCG_00427 6.1e-149 glcU U Glucose uptake
LOPFHFCG_00428 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_00429 1.3e-100 ycnI S protein conserved in bacteria
LOPFHFCG_00430 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
LOPFHFCG_00431 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
LOPFHFCG_00432 7.3e-56
LOPFHFCG_00433 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
LOPFHFCG_00434 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LOPFHFCG_00435 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
LOPFHFCG_00436 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LOPFHFCG_00437 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LOPFHFCG_00438 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LOPFHFCG_00439 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
LOPFHFCG_00440 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
LOPFHFCG_00442 1.2e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LOPFHFCG_00443 1.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
LOPFHFCG_00444 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LOPFHFCG_00445 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
LOPFHFCG_00446 1.8e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
LOPFHFCG_00447 5.6e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LOPFHFCG_00448 2.7e-132 kipR K Transcriptional regulator
LOPFHFCG_00449 2.9e-119 ycsK E anatomical structure formation involved in morphogenesis
LOPFHFCG_00451 5.4e-49 yczJ S biosynthesis
LOPFHFCG_00452 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
LOPFHFCG_00453 2.8e-176 ydhF S Oxidoreductase
LOPFHFCG_00454 0.0 mtlR K transcriptional regulator, MtlR
LOPFHFCG_00455 1.4e-294 ydaB IQ acyl-CoA ligase
LOPFHFCG_00456 1.1e-99 ydaC Q Methyltransferase domain
LOPFHFCG_00457 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_00458 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
LOPFHFCG_00459 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LOPFHFCG_00460 6.8e-77 ydaG 1.4.3.5 S general stress protein
LOPFHFCG_00461 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LOPFHFCG_00462 5.1e-47 ydzA EGP Major facilitator Superfamily
LOPFHFCG_00463 2.5e-74 lrpC K Transcriptional regulator
LOPFHFCG_00464 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOPFHFCG_00465 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
LOPFHFCG_00466 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
LOPFHFCG_00467 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
LOPFHFCG_00468 4.5e-233 ydaM M Glycosyl transferase family group 2
LOPFHFCG_00469 0.0 ydaN S Bacterial cellulose synthase subunit
LOPFHFCG_00470 0.0 ydaO E amino acid
LOPFHFCG_00471 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LOPFHFCG_00472 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LOPFHFCG_00473 9.4e-40
LOPFHFCG_00474 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
LOPFHFCG_00476 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
LOPFHFCG_00477 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
LOPFHFCG_00479 8.9e-59 ydbB G Cupin domain
LOPFHFCG_00480 2.8e-63 ydbC S Domain of unknown function (DUF4937
LOPFHFCG_00481 3.2e-155 ydbD P Catalase
LOPFHFCG_00482 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LOPFHFCG_00483 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LOPFHFCG_00484 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
LOPFHFCG_00485 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOPFHFCG_00486 4.4e-181 ydbI S AI-2E family transporter
LOPFHFCG_00487 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
LOPFHFCG_00488 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LOPFHFCG_00489 2.7e-52 ydbL
LOPFHFCG_00490 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LOPFHFCG_00491 1.1e-18 S Fur-regulated basic protein B
LOPFHFCG_00492 2.2e-07 S Fur-regulated basic protein A
LOPFHFCG_00493 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOPFHFCG_00494 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LOPFHFCG_00495 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LOPFHFCG_00496 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LOPFHFCG_00497 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LOPFHFCG_00498 2.1e-82 ydbS S Bacterial PH domain
LOPFHFCG_00499 2.2e-263 ydbT S Membrane
LOPFHFCG_00500 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
LOPFHFCG_00501 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LOPFHFCG_00502 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
LOPFHFCG_00503 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LOPFHFCG_00504 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LOPFHFCG_00505 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
LOPFHFCG_00506 1.3e-143 rsbR T Positive regulator of sigma-B
LOPFHFCG_00507 5.2e-57 rsbS T antagonist
LOPFHFCG_00508 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LOPFHFCG_00509 7.1e-189 rsbU 3.1.3.3 KT phosphatase
LOPFHFCG_00510 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
LOPFHFCG_00511 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LOPFHFCG_00512 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOPFHFCG_00513 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
LOPFHFCG_00517 1.5e-82 ydcG S EVE domain
LOPFHFCG_00518 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
LOPFHFCG_00519 0.0 yhgF K COG2183 Transcriptional accessory protein
LOPFHFCG_00520 1.6e-84 ydcK S Belongs to the SprT family
LOPFHFCG_00528 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_00529 2.4e-71 lrpA K transcriptional
LOPFHFCG_00530 3.9e-78 lrpB K transcriptional
LOPFHFCG_00531 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
LOPFHFCG_00532 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
LOPFHFCG_00533 5e-227 ydeG EGP Major facilitator Superfamily
LOPFHFCG_00538 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LOPFHFCG_00539 8.7e-30 cspL K Cold shock
LOPFHFCG_00540 6.1e-79 carD K Transcription factor
LOPFHFCG_00541 4.6e-35 ydzE EG spore germination
LOPFHFCG_00542 1.1e-166 rhaS5 K AraC-like ligand binding domain
LOPFHFCG_00543 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LOPFHFCG_00544 2.5e-166 ydeE K AraC family transcriptional regulator
LOPFHFCG_00545 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOPFHFCG_00546 3.4e-220 ydeG EGP Major facilitator superfamily
LOPFHFCG_00547 2.9e-47 ydeH
LOPFHFCG_00548 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
LOPFHFCG_00549 4e-116
LOPFHFCG_00550 1.8e-153 ydeK EG -transporter
LOPFHFCG_00551 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOPFHFCG_00552 4.2e-74 maoC I N-terminal half of MaoC dehydratase
LOPFHFCG_00553 8.6e-107 ydeN S Serine hydrolase
LOPFHFCG_00554 1.1e-58 K HxlR-like helix-turn-helix
LOPFHFCG_00555 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LOPFHFCG_00556 4.8e-69 ydeP K Transcriptional regulator
LOPFHFCG_00557 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
LOPFHFCG_00558 1.2e-195 ydeR EGP Major facilitator Superfamily
LOPFHFCG_00559 8.4e-105 ydeS K Transcriptional regulator
LOPFHFCG_00560 1.3e-57 arsR K transcriptional
LOPFHFCG_00561 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LOPFHFCG_00562 7.2e-149 ydfB J GNAT acetyltransferase
LOPFHFCG_00563 1e-162 ydfC EG EamA-like transporter family
LOPFHFCG_00564 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOPFHFCG_00565 5.9e-117 ydfE S Flavin reductase like domain
LOPFHFCG_00566 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
LOPFHFCG_00567 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LOPFHFCG_00569 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
LOPFHFCG_00570 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOPFHFCG_00571 0.0 ydfJ S drug exporters of the RND superfamily
LOPFHFCG_00572 1.9e-177 S Alpha/beta hydrolase family
LOPFHFCG_00573 5.9e-118 S Protein of unknown function (DUF554)
LOPFHFCG_00574 3.2e-147 K Bacterial transcription activator, effector binding domain
LOPFHFCG_00575 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOPFHFCG_00576 9.6e-112 ydfN C nitroreductase
LOPFHFCG_00577 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
LOPFHFCG_00578 8.8e-63 mhqP S DoxX
LOPFHFCG_00579 1.3e-57 traF CO Thioredoxin
LOPFHFCG_00580 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
LOPFHFCG_00581 6.3e-29
LOPFHFCG_00583 4.4e-118 ydfR S Protein of unknown function (DUF421)
LOPFHFCG_00584 5.2e-122 ydfS S Protein of unknown function (DUF421)
LOPFHFCG_00585 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
LOPFHFCG_00586 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
LOPFHFCG_00587 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
LOPFHFCG_00588 1e-99 K Bacterial regulatory proteins, tetR family
LOPFHFCG_00589 4.8e-52 S DoxX-like family
LOPFHFCG_00590 2.9e-84 yycN 2.3.1.128 K Acetyltransferase
LOPFHFCG_00591 2.7e-302 expZ S ABC transporter
LOPFHFCG_00592 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_00593 2.3e-90 dinB S DinB family
LOPFHFCG_00594 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
LOPFHFCG_00595 0.0 ydgH S drug exporters of the RND superfamily
LOPFHFCG_00596 1e-113 drgA C nitroreductase
LOPFHFCG_00597 1.1e-69 ydgJ K Winged helix DNA-binding domain
LOPFHFCG_00598 2.5e-209 tcaB EGP Major facilitator Superfamily
LOPFHFCG_00599 1.2e-121 ydhB S membrane transporter protein
LOPFHFCG_00600 5.5e-121 ydhC K FCD
LOPFHFCG_00601 4.2e-231 ydhD M Glycosyl hydrolase
LOPFHFCG_00602 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LOPFHFCG_00603 6e-126
LOPFHFCG_00604 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LOPFHFCG_00605 4.6e-69 frataxin S Domain of unknown function (DU1801)
LOPFHFCG_00607 1e-81 K Acetyltransferase (GNAT) domain
LOPFHFCG_00608 8.4e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
LOPFHFCG_00609 2.3e-99 ydhK M Protein of unknown function (DUF1541)
LOPFHFCG_00610 1.8e-199 pbuE EGP Major facilitator Superfamily
LOPFHFCG_00611 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
LOPFHFCG_00612 1.9e-30 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
LOPFHFCG_00613 6.4e-137 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOPFHFCG_00614 2.2e-91 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOPFHFCG_00615 2.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOPFHFCG_00616 3.9e-133 ydhQ K UTRA
LOPFHFCG_00617 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
LOPFHFCG_00618 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
LOPFHFCG_00619 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
LOPFHFCG_00620 8.7e-78 ydhU P Catalase
LOPFHFCG_00621 1.1e-16 ydhU P Manganese containing catalase
LOPFHFCG_00624 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_00625 7.8e-08
LOPFHFCG_00627 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LOPFHFCG_00628 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
LOPFHFCG_00629 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
LOPFHFCG_00630 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LOPFHFCG_00631 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LOPFHFCG_00632 0.0 ydiF S ABC transporter
LOPFHFCG_00633 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LOPFHFCG_00634 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LOPFHFCG_00635 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LOPFHFCG_00636 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LOPFHFCG_00637 2.9e-27 ydiK S Domain of unknown function (DUF4305)
LOPFHFCG_00638 7.9e-129 ydiL S CAAX protease self-immunity
LOPFHFCG_00639 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LOPFHFCG_00640 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LOPFHFCG_00642 6.4e-66 KL Phage plasmid primase P4 family
LOPFHFCG_00643 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
LOPFHFCG_00644 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LOPFHFCG_00646 1.2e-199 V AAA domain (dynein-related subfamily)
LOPFHFCG_00647 4.9e-257 J LlaJI restriction endonuclease
LOPFHFCG_00648 1.1e-08 ydjC S Abhydrolase domain containing 18
LOPFHFCG_00649 0.0 K NB-ARC domain
LOPFHFCG_00650 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
LOPFHFCG_00651 3.5e-255 gutA G MFS/sugar transport protein
LOPFHFCG_00652 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
LOPFHFCG_00653 5.1e-114 pspA KT Phage shock protein A
LOPFHFCG_00654 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOPFHFCG_00655 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
LOPFHFCG_00656 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
LOPFHFCG_00657 4.7e-196 S Ion transport 2 domain protein
LOPFHFCG_00658 2.7e-258 iolT EGP Major facilitator Superfamily
LOPFHFCG_00659 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LOPFHFCG_00660 4.5e-64 ydjM M Lytic transglycolase
LOPFHFCG_00661 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
LOPFHFCG_00663 1.4e-34 ydjO S Cold-inducible protein YdjO
LOPFHFCG_00664 9.5e-160 ydjP I Alpha/beta hydrolase family
LOPFHFCG_00665 2.4e-181 yeaA S Protein of unknown function (DUF4003)
LOPFHFCG_00666 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
LOPFHFCG_00667 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_00668 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LOPFHFCG_00669 1.6e-177 yeaC S COG0714 MoxR-like ATPases
LOPFHFCG_00670 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LOPFHFCG_00671 0.0 yebA E COG1305 Transglutaminase-like enzymes
LOPFHFCG_00672 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LOPFHFCG_00673 3.3e-210 pbuG S permease
LOPFHFCG_00674 2.3e-118 yebC M Membrane
LOPFHFCG_00676 4e-93 yebE S UPF0316 protein
LOPFHFCG_00677 8e-28 yebG S NETI protein
LOPFHFCG_00678 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LOPFHFCG_00679 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LOPFHFCG_00680 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LOPFHFCG_00681 3.7e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LOPFHFCG_00682 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOPFHFCG_00683 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOPFHFCG_00684 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LOPFHFCG_00685 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LOPFHFCG_00686 1.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LOPFHFCG_00687 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LOPFHFCG_00688 4.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LOPFHFCG_00689 5e-232 purD 6.3.4.13 F Belongs to the GARS family
LOPFHFCG_00690 1e-72 K helix_turn_helix ASNC type
LOPFHFCG_00691 3.2e-226 yjeH E Amino acid permease
LOPFHFCG_00692 0.0 yerA 3.5.4.2 F adenine deaminase
LOPFHFCG_00693 1.1e-186 yerB S Protein of unknown function (DUF3048) C-terminal domain
LOPFHFCG_00694 2.4e-50 yerC S protein conserved in bacteria
LOPFHFCG_00695 5.2e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
LOPFHFCG_00697 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LOPFHFCG_00698 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LOPFHFCG_00699 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LOPFHFCG_00700 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
LOPFHFCG_00701 1.4e-45 L transposase activity
LOPFHFCG_00702 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
LOPFHFCG_00703 7.8e-196 yerI S homoserine kinase type II (protein kinase fold)
LOPFHFCG_00704 1.6e-123 sapB S MgtC SapB transporter
LOPFHFCG_00705 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOPFHFCG_00706 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LOPFHFCG_00707 2.3e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LOPFHFCG_00708 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LOPFHFCG_00709 2.8e-146 yerO K Transcriptional regulator
LOPFHFCG_00710 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LOPFHFCG_00711 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LOPFHFCG_00712 4.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOPFHFCG_00713 5e-20
LOPFHFCG_00714 0.0 K SIR2-like domain
LOPFHFCG_00716 3.4e-56 S Protein of unknown function, DUF600
LOPFHFCG_00717 0.0 L nucleic acid phosphodiester bond hydrolysis
LOPFHFCG_00718 7e-97 3.4.24.40 CO amine dehydrogenase activity
LOPFHFCG_00719 3.6e-58 3.4.24.40 CO amine dehydrogenase activity
LOPFHFCG_00720 1.6e-210 S Tetratricopeptide repeat
LOPFHFCG_00722 2.7e-126 yeeN K transcriptional regulatory protein
LOPFHFCG_00724 6.7e-99 dhaR3 K Transcriptional regulator
LOPFHFCG_00725 1.5e-44 cotJA S Spore coat associated protein JA (CotJA)
LOPFHFCG_00726 5.6e-45 cotJB S CotJB protein
LOPFHFCG_00727 2e-103 cotJC P Spore Coat
LOPFHFCG_00728 6e-102 yesJ K Acetyltransferase (GNAT) family
LOPFHFCG_00729 3.1e-102 yesL S Protein of unknown function, DUF624
LOPFHFCG_00730 0.0 yesM 2.7.13.3 T Histidine kinase
LOPFHFCG_00731 1.7e-157 yesN K helix_turn_helix, arabinose operon control protein
LOPFHFCG_00732 5.2e-245 yesO G Bacterial extracellular solute-binding protein
LOPFHFCG_00733 1e-170 yesP G Binding-protein-dependent transport system inner membrane component
LOPFHFCG_00734 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
LOPFHFCG_00735 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
LOPFHFCG_00736 0.0 yesS K Transcriptional regulator
LOPFHFCG_00737 5e-133 E GDSL-like Lipase/Acylhydrolase
LOPFHFCG_00738 4.6e-128 yesU S Domain of unknown function (DUF1961)
LOPFHFCG_00739 5.7e-112 yesV S Protein of unknown function, DUF624
LOPFHFCG_00740 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
LOPFHFCG_00741 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
LOPFHFCG_00742 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
LOPFHFCG_00743 2.3e-64 yesZ 3.2.1.23 G beta-galactosidase activity
LOPFHFCG_00744 7.2e-124 yesZ 3.2.1.23 G beta-galactosidase activity
LOPFHFCG_00745 1.3e-156 yesZ 3.2.1.23 G beta-galactosidase activity
LOPFHFCG_00746 4.2e-104 yetA
LOPFHFCG_00747 3.9e-189 yetA
LOPFHFCG_00748 1.4e-172 yetA
LOPFHFCG_00749 3.2e-286 lplA G Bacterial extracellular solute-binding protein
LOPFHFCG_00750 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
LOPFHFCG_00751 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
LOPFHFCG_00752 2.4e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LOPFHFCG_00753 4e-122 yetF S membrane
LOPFHFCG_00754 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LOPFHFCG_00755 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOPFHFCG_00756 2.5e-34
LOPFHFCG_00757 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LOPFHFCG_00758 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
LOPFHFCG_00759 2.6e-104 yetJ S Belongs to the BI1 family
LOPFHFCG_00760 8.3e-31 yetM CH FAD binding domain
LOPFHFCG_00761 6.2e-133 M Membrane
LOPFHFCG_00762 1.2e-238 L COG3328 Transposase and inactivated derivatives
LOPFHFCG_00763 3.7e-196 yetN S Protein of unknown function (DUF3900)
LOPFHFCG_00764 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LOPFHFCG_00765 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOPFHFCG_00766 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
LOPFHFCG_00767 1.9e-172 yfnG 4.2.1.45 M dehydratase
LOPFHFCG_00768 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
LOPFHFCG_00769 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
LOPFHFCG_00770 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
LOPFHFCG_00771 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
LOPFHFCG_00772 3.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LOPFHFCG_00773 6.4e-241 yfnA E amino acid
LOPFHFCG_00774 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOPFHFCG_00775 1.1e-113 yfmS NT chemotaxis protein
LOPFHFCG_00776 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LOPFHFCG_00777 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
LOPFHFCG_00778 2.8e-70 yfmP K transcriptional
LOPFHFCG_00779 1.5e-209 yfmO EGP Major facilitator Superfamily
LOPFHFCG_00780 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LOPFHFCG_00781 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
LOPFHFCG_00782 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
LOPFHFCG_00783 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
LOPFHFCG_00784 7.7e-214 G Major Facilitator Superfamily
LOPFHFCG_00785 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
LOPFHFCG_00786 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
LOPFHFCG_00787 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_00788 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_00789 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LOPFHFCG_00790 2.9e-24 S Protein of unknown function (DUF3212)
LOPFHFCG_00791 7.6e-58 yflT S Heat induced stress protein YflT
LOPFHFCG_00792 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
LOPFHFCG_00793 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
LOPFHFCG_00794 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LOPFHFCG_00795 8.9e-119 citT T response regulator
LOPFHFCG_00796 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
LOPFHFCG_00798 8.5e-227 citM C Citrate transporter
LOPFHFCG_00799 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
LOPFHFCG_00800 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LOPFHFCG_00801 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LOPFHFCG_00802 9e-124 yflK S protein conserved in bacteria
LOPFHFCG_00803 4e-18 yflJ S Protein of unknown function (DUF2639)
LOPFHFCG_00804 4.1e-19 yflI
LOPFHFCG_00805 2.4e-50 yflH S Protein of unknown function (DUF3243)
LOPFHFCG_00806 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
LOPFHFCG_00807 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LOPFHFCG_00808 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOPFHFCG_00809 6e-67 yhdN S Domain of unknown function (DUF1992)
LOPFHFCG_00810 3.2e-256 agcS_1 E Sodium alanine symporter
LOPFHFCG_00811 1.6e-194 E Spore germination protein
LOPFHFCG_00813 5.1e-207 yfkR S spore germination
LOPFHFCG_00814 1.5e-283 yfkQ EG Spore germination protein
LOPFHFCG_00815 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOPFHFCG_00816 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LOPFHFCG_00817 1.8e-133 treR K transcriptional
LOPFHFCG_00818 1.6e-125 yfkO C nitroreductase
LOPFHFCG_00819 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LOPFHFCG_00820 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
LOPFHFCG_00821 6.8e-207 ydiM EGP Major facilitator Superfamily
LOPFHFCG_00822 2.1e-29 yfkK S Belongs to the UPF0435 family
LOPFHFCG_00823 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOPFHFCG_00824 8.4e-51 yfkI S gas vesicle protein
LOPFHFCG_00825 9.7e-144 yihY S Belongs to the UPF0761 family
LOPFHFCG_00826 5e-08
LOPFHFCG_00827 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
LOPFHFCG_00828 6.1e-183 cax P COG0387 Ca2 H antiporter
LOPFHFCG_00829 1.2e-146 yfkD S YfkD-like protein
LOPFHFCG_00830 6e-149 yfkC M Mechanosensitive ion channel
LOPFHFCG_00831 5.4e-222 yfkA S YfkB-like domain
LOPFHFCG_00832 1.1e-26 yfjT
LOPFHFCG_00833 2.6e-154 pdaA G deacetylase
LOPFHFCG_00834 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LOPFHFCG_00835 8.5e-184 corA P Mediates influx of magnesium ions
LOPFHFCG_00836 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LOPFHFCG_00837 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LOPFHFCG_00838 3.9e-44 S YfzA-like protein
LOPFHFCG_00839 2e-188 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LOPFHFCG_00840 3.9e-86 yfjM S Psort location Cytoplasmic, score
LOPFHFCG_00841 3e-29 yfjL
LOPFHFCG_00842 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LOPFHFCG_00843 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LOPFHFCG_00844 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LOPFHFCG_00845 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LOPFHFCG_00846 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
LOPFHFCG_00847 1.2e-25 sspH S Belongs to the SspH family
LOPFHFCG_00848 4e-56 yfjF S UPF0060 membrane protein
LOPFHFCG_00849 1.3e-80 S Family of unknown function (DUF5381)
LOPFHFCG_00850 1.8e-101 yfjD S Family of unknown function (DUF5381)
LOPFHFCG_00851 4.1e-144 yfjC
LOPFHFCG_00852 9.2e-191 yfjB
LOPFHFCG_00853 1.1e-44 yfjA S Belongs to the WXG100 family
LOPFHFCG_00854 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LOPFHFCG_00855 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
LOPFHFCG_00856 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOPFHFCG_00857 2.1e-310 yfiB3 V ABC transporter
LOPFHFCG_00858 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOPFHFCG_00859 8.3e-64 mhqP S DoxX
LOPFHFCG_00860 7.4e-163 yfiE 1.13.11.2 S glyoxalase
LOPFHFCG_00861 1.5e-177 K AraC-like ligand binding domain
LOPFHFCG_00862 1.8e-262 iolT EGP Major facilitator Superfamily
LOPFHFCG_00863 8.4e-184 G Xylose isomerase
LOPFHFCG_00864 1.1e-233 S Oxidoreductase
LOPFHFCG_00866 1.1e-214 yxjM T Histidine kinase
LOPFHFCG_00867 3.2e-113 KT LuxR family transcriptional regulator
LOPFHFCG_00868 6.2e-171 V ABC transporter, ATP-binding protein
LOPFHFCG_00869 9.8e-214 V ABC-2 family transporter protein
LOPFHFCG_00870 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
LOPFHFCG_00871 8.3e-99 padR K transcriptional
LOPFHFCG_00872 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LOPFHFCG_00873 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LOPFHFCG_00874 2e-109 yfiR K Transcriptional regulator
LOPFHFCG_00875 5.1e-221 yfiS EGP Major facilitator Superfamily
LOPFHFCG_00876 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
LOPFHFCG_00877 8.7e-287 yfiU EGP Major facilitator Superfamily
LOPFHFCG_00878 3.1e-81 yfiV K transcriptional
LOPFHFCG_00879 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LOPFHFCG_00880 6.2e-182 yfiY P ABC transporter substrate-binding protein
LOPFHFCG_00881 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_00882 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_00883 1.8e-167 yfhB 5.3.3.17 S PhzF family
LOPFHFCG_00884 3.9e-107 yfhC C nitroreductase
LOPFHFCG_00885 2.1e-25 yfhD S YfhD-like protein
LOPFHFCG_00887 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
LOPFHFCG_00888 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
LOPFHFCG_00889 9.7e-52 yfhH S Protein of unknown function (DUF1811)
LOPFHFCG_00891 1.1e-209 yfhI EGP Major facilitator Superfamily
LOPFHFCG_00892 6.2e-20 sspK S reproduction
LOPFHFCG_00893 1.3e-44 yfhJ S WVELL protein
LOPFHFCG_00894 9.2e-92 batE T Bacterial SH3 domain homologues
LOPFHFCG_00895 3.5e-51 yfhL S SdpI/YhfL protein family
LOPFHFCG_00896 6.7e-172 yfhM S Alpha beta hydrolase
LOPFHFCG_00897 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOPFHFCG_00898 0.0 yfhO S Bacterial membrane protein YfhO
LOPFHFCG_00899 5.5e-186 yfhP S membrane-bound metal-dependent
LOPFHFCG_00900 7.8e-212 mutY L A G-specific
LOPFHFCG_00901 6.9e-36 yfhS
LOPFHFCG_00902 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_00903 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
LOPFHFCG_00904 4.9e-48 ygaB S YgaB-like protein
LOPFHFCG_00905 1.3e-104 ygaC J Belongs to the UPF0374 family
LOPFHFCG_00906 1.8e-301 ygaD V ABC transporter
LOPFHFCG_00907 8.7e-180 ygaE S Membrane
LOPFHFCG_00908 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LOPFHFCG_00909 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
LOPFHFCG_00910 4e-80 perR P Belongs to the Fur family
LOPFHFCG_00911 1.5e-56 ygzB S UPF0295 protein
LOPFHFCG_00912 6.7e-167 ygxA S Nucleotidyltransferase-like
LOPFHFCG_00913 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_00918 7.8e-08
LOPFHFCG_00926 5.9e-08
LOPFHFCG_00930 2.7e-143 spo0M S COG4326 Sporulation control protein
LOPFHFCG_00931 3e-27
LOPFHFCG_00932 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
LOPFHFCG_00934 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LOPFHFCG_00935 1.9e-266 ygaK C Berberine and berberine like
LOPFHFCG_00937 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LOPFHFCG_00938 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LOPFHFCG_00939 1.7e-171 ssuA M Sulfonate ABC transporter
LOPFHFCG_00940 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LOPFHFCG_00941 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LOPFHFCG_00943 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LOPFHFCG_00944 4.1e-78 ygaO
LOPFHFCG_00945 4.4e-29 K Transcriptional regulator
LOPFHFCG_00947 7.9e-114 yhzB S B3/4 domain
LOPFHFCG_00948 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LOPFHFCG_00949 4.4e-177 yhbB S Putative amidase domain
LOPFHFCG_00950 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LOPFHFCG_00951 1.2e-109 yhbD K Protein of unknown function (DUF4004)
LOPFHFCG_00952 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
LOPFHFCG_00953 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
LOPFHFCG_00954 0.0 prkA T Ser protein kinase
LOPFHFCG_00955 2.5e-225 yhbH S Belongs to the UPF0229 family
LOPFHFCG_00956 2.2e-76 yhbI K DNA-binding transcription factor activity
LOPFHFCG_00957 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
LOPFHFCG_00958 3.1e-271 yhcA EGP Major facilitator Superfamily
LOPFHFCG_00959 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
LOPFHFCG_00960 2.8e-37 yhcC
LOPFHFCG_00961 7.8e-55
LOPFHFCG_00962 6.6e-60 yhcF K Transcriptional regulator
LOPFHFCG_00963 1.6e-123 yhcG V ABC transporter, ATP-binding protein
LOPFHFCG_00964 2.6e-166 yhcH V ABC transporter, ATP-binding protein
LOPFHFCG_00965 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LOPFHFCG_00966 1e-30 cspB K Cold-shock protein
LOPFHFCG_00967 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
LOPFHFCG_00968 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
LOPFHFCG_00969 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOPFHFCG_00970 3.7e-44 yhcM
LOPFHFCG_00971 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LOPFHFCG_00972 3e-149 yhcP
LOPFHFCG_00973 7.2e-86 yhcQ M Spore coat protein
LOPFHFCG_00974 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
LOPFHFCG_00975 1e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LOPFHFCG_00976 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LOPFHFCG_00977 9.3e-68 yhcU S Family of unknown function (DUF5365)
LOPFHFCG_00978 3.8e-67 yhcV S COG0517 FOG CBS domain
LOPFHFCG_00979 1e-119 yhcW 5.4.2.6 S hydrolase
LOPFHFCG_00980 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LOPFHFCG_00981 4.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LOPFHFCG_00982 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LOPFHFCG_00983 1.7e-151 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LOPFHFCG_00984 1.3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LOPFHFCG_00985 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LOPFHFCG_00986 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LOPFHFCG_00987 4e-212 yhcY 2.7.13.3 T Histidine kinase
LOPFHFCG_00988 3.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOPFHFCG_00989 2.1e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
LOPFHFCG_00990 1.2e-38 yhdB S YhdB-like protein
LOPFHFCG_00991 1.8e-53 yhdC S Protein of unknown function (DUF3889)
LOPFHFCG_00992 6.7e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LOPFHFCG_00993 3.5e-76 nsrR K Transcriptional regulator
LOPFHFCG_00994 8.7e-239 ygxB M Conserved TM helix
LOPFHFCG_00995 2.1e-276 ycgB S Stage V sporulation protein R
LOPFHFCG_00996 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LOPFHFCG_00997 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LOPFHFCG_00998 3.8e-162 citR K Transcriptional regulator
LOPFHFCG_00999 3.2e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
LOPFHFCG_01000 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_01001 3.4e-250 yhdG E amino acid
LOPFHFCG_01002 3.7e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LOPFHFCG_01003 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOPFHFCG_01004 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOPFHFCG_01005 8.1e-45 yhdK S Sigma-M inhibitor protein
LOPFHFCG_01006 3.3e-200 yhdL S Sigma factor regulator N-terminal
LOPFHFCG_01007 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_01008 5.7e-191 yhdN C Aldo keto reductase
LOPFHFCG_01009 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LOPFHFCG_01010 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LOPFHFCG_01011 4.1e-74 cueR K transcriptional
LOPFHFCG_01012 6.4e-73 yhdR 2.6.1.1 E Aminotransferase
LOPFHFCG_01013 1.9e-135 yhdR 2.6.1.1 E Aminotransferase
LOPFHFCG_01014 2.3e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
LOPFHFCG_01015 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOPFHFCG_01016 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LOPFHFCG_01017 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LOPFHFCG_01019 2.1e-202 yhdY M Mechanosensitive ion channel
LOPFHFCG_01020 1.1e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LOPFHFCG_01021 7.4e-147 yheN G deacetylase
LOPFHFCG_01022 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LOPFHFCG_01023 6.8e-227 nhaC C Na H antiporter
LOPFHFCG_01024 1.5e-83 nhaX T Belongs to the universal stress protein A family
LOPFHFCG_01025 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOPFHFCG_01026 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOPFHFCG_01027 4.5e-109 yheG GM NAD(P)H-binding
LOPFHFCG_01028 6.3e-28 sspB S spore protein
LOPFHFCG_01029 8.3e-201 L COG3666 Transposase and inactivated derivatives
LOPFHFCG_01030 1.3e-36 yheE S Family of unknown function (DUF5342)
LOPFHFCG_01031 8.2e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
LOPFHFCG_01032 1.6e-215 yheC HJ YheC/D like ATP-grasp
LOPFHFCG_01033 1.4e-201 yheB S Belongs to the UPF0754 family
LOPFHFCG_01034 9.5e-48 yheA S Belongs to the UPF0342 family
LOPFHFCG_01035 5.3e-104 yhaZ L DNA alkylation repair enzyme
LOPFHFCG_01036 2.9e-73 yhaZ L DNA alkylation repair enzyme
LOPFHFCG_01037 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
LOPFHFCG_01038 1.8e-292 hemZ H coproporphyrinogen III oxidase
LOPFHFCG_01039 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
LOPFHFCG_01040 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
LOPFHFCG_01042 6.4e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
LOPFHFCG_01043 3.2e-26 S YhzD-like protein
LOPFHFCG_01044 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
LOPFHFCG_01045 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
LOPFHFCG_01046 2.6e-225 yhaO L DNA repair exonuclease
LOPFHFCG_01047 0.0 yhaN L AAA domain
LOPFHFCG_01048 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
LOPFHFCG_01049 1.6e-21 yhaL S Sporulation protein YhaL
LOPFHFCG_01050 1.1e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LOPFHFCG_01051 1.5e-89 yhaK S Putative zincin peptidase
LOPFHFCG_01052 2.2e-54 yhaI S Protein of unknown function (DUF1878)
LOPFHFCG_01053 1e-113 hpr K Negative regulator of protease production and sporulation
LOPFHFCG_01054 7e-39 yhaH S YtxH-like protein
LOPFHFCG_01055 5.4e-21
LOPFHFCG_01056 3.6e-80 trpP S Tryptophan transporter TrpP
LOPFHFCG_01057 2.9e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LOPFHFCG_01058 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LOPFHFCG_01059 4.6e-137 ecsA V transporter (ATP-binding protein)
LOPFHFCG_01060 4.5e-214 ecsB U ABC transporter
LOPFHFCG_01061 1e-112 ecsC S EcsC protein family
LOPFHFCG_01062 9.2e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LOPFHFCG_01063 1.6e-244 yhfA C membrane
LOPFHFCG_01064 1.6e-33 1.15.1.2 C Rubrerythrin
LOPFHFCG_01065 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LOPFHFCG_01066 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LOPFHFCG_01067 2.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LOPFHFCG_01068 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LOPFHFCG_01069 3.8e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LOPFHFCG_01070 5.4e-101 yhgD K Transcriptional regulator
LOPFHFCG_01071 1.5e-213 yhgE S YhgE Pip N-terminal domain protein
LOPFHFCG_01072 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOPFHFCG_01073 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
LOPFHFCG_01074 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
LOPFHFCG_01075 4.1e-71 3.4.13.21 S ASCH
LOPFHFCG_01076 8.4e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LOPFHFCG_01077 1.2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LOPFHFCG_01078 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
LOPFHFCG_01079 2.9e-111 yhfK GM NmrA-like family
LOPFHFCG_01080 3.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LOPFHFCG_01081 1.3e-64 yhfM
LOPFHFCG_01082 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
LOPFHFCG_01083 5.2e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
LOPFHFCG_01084 6.2e-76 VY92_01935 K acetyltransferase
LOPFHFCG_01085 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
LOPFHFCG_01086 1e-155 yfmC M Periplasmic binding protein
LOPFHFCG_01087 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LOPFHFCG_01088 2e-197 vraB 2.3.1.9 I Belongs to the thiolase family
LOPFHFCG_01089 2.6e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LOPFHFCG_01090 5e-91 bioY S BioY family
LOPFHFCG_01091 2.4e-181 hemAT NT chemotaxis protein
LOPFHFCG_01092 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LOPFHFCG_01093 6e-120 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LOPFHFCG_01094 8.3e-30 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LOPFHFCG_01095 2.3e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_01096 1.3e-32 yhzC S IDEAL
LOPFHFCG_01097 4.2e-109 comK K Competence transcription factor
LOPFHFCG_01098 3.5e-163 IQ Enoyl-(Acyl carrier protein) reductase
LOPFHFCG_01099 2.8e-39 yhjA S Excalibur calcium-binding domain
LOPFHFCG_01100 3.4e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOPFHFCG_01101 6.9e-27 yhjC S Protein of unknown function (DUF3311)
LOPFHFCG_01102 6.7e-60 yhjD
LOPFHFCG_01103 5.9e-109 yhjE S SNARE associated Golgi protein
LOPFHFCG_01104 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
LOPFHFCG_01105 1.3e-282 yhjG CH FAD binding domain
LOPFHFCG_01106 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
LOPFHFCG_01109 4.2e-212 glcP G Major Facilitator Superfamily
LOPFHFCG_01110 3.5e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
LOPFHFCG_01111 2e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
LOPFHFCG_01112 1e-251 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
LOPFHFCG_01113 3.8e-187 yhjM 5.1.1.1 K Transcriptional regulator
LOPFHFCG_01114 7.8e-200 abrB S membrane
LOPFHFCG_01115 3.9e-210 EGP Transmembrane secretion effector
LOPFHFCG_01116 0.0 S Sugar transport-related sRNA regulator N-term
LOPFHFCG_01117 8.3e-201 L COG3666 Transposase and inactivated derivatives
LOPFHFCG_01118 2.2e-78 yhjR S Rubrerythrin
LOPFHFCG_01119 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
LOPFHFCG_01120 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LOPFHFCG_01121 4.5e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LOPFHFCG_01122 0.0 sbcC L COG0419 ATPase involved in DNA repair
LOPFHFCG_01123 3e-50 yisB V COG1403 Restriction endonuclease
LOPFHFCG_01124 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
LOPFHFCG_01125 7.5e-65 gerPE S Spore germination protein GerPE
LOPFHFCG_01126 3.1e-23 gerPD S Spore germination protein
LOPFHFCG_01127 5.3e-54 gerPC S Spore germination protein
LOPFHFCG_01128 4e-34 gerPB S cell differentiation
LOPFHFCG_01129 5.4e-33 gerPA S Spore germination protein
LOPFHFCG_01130 1.5e-22 yisI S Spo0E like sporulation regulatory protein
LOPFHFCG_01131 9.1e-175 cotH M Spore Coat
LOPFHFCG_01132 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LOPFHFCG_01133 3.9e-57 yisL S UPF0344 protein
LOPFHFCG_01134 0.0 wprA O Belongs to the peptidase S8 family
LOPFHFCG_01135 1.5e-100 yisN S Protein of unknown function (DUF2777)
LOPFHFCG_01136 0.0 asnO 6.3.5.4 E Asparagine synthase
LOPFHFCG_01137 1.2e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
LOPFHFCG_01138 5.2e-243 yisQ V Mate efflux family protein
LOPFHFCG_01139 4.5e-160 yisR K Transcriptional regulator
LOPFHFCG_01140 6.5e-182 purR K helix_turn _helix lactose operon repressor
LOPFHFCG_01141 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
LOPFHFCG_01142 7e-92 yisT S DinB family
LOPFHFCG_01143 1.2e-106 argO S Lysine exporter protein LysE YggA
LOPFHFCG_01144 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LOPFHFCG_01145 2e-35 mcbG S Pentapeptide repeats (9 copies)
LOPFHFCG_01146 2.7e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LOPFHFCG_01147 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
LOPFHFCG_01148 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LOPFHFCG_01149 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LOPFHFCG_01150 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
LOPFHFCG_01151 1.9e-141 yitD 4.4.1.19 S synthase
LOPFHFCG_01152 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOPFHFCG_01153 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LOPFHFCG_01154 4e-229 yitG EGP Major facilitator Superfamily
LOPFHFCG_01155 1.8e-161 yitH K Acetyltransferase (GNAT) domain
LOPFHFCG_01156 2e-82 yjcF S Acetyltransferase (GNAT) domain
LOPFHFCG_01157 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LOPFHFCG_01158 8.6e-55 yajQ S Belongs to the UPF0234 family
LOPFHFCG_01159 4e-161 cvfB S protein conserved in bacteria
LOPFHFCG_01160 8.5e-94
LOPFHFCG_01161 2.8e-171
LOPFHFCG_01162 1.5e-97 S Sporulation delaying protein SdpA
LOPFHFCG_01163 1.5e-58 K Transcriptional regulator PadR-like family
LOPFHFCG_01164 2e-95
LOPFHFCG_01165 1.4e-44 yitR S Domain of unknown function (DUF3784)
LOPFHFCG_01166 2.2e-311 nprB 3.4.24.28 E Peptidase M4
LOPFHFCG_01167 8.4e-159 yitS S protein conserved in bacteria
LOPFHFCG_01168 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
LOPFHFCG_01169 1.9e-72 ipi S Intracellular proteinase inhibitor
LOPFHFCG_01170 1.2e-17 S Protein of unknown function (DUF3813)
LOPFHFCG_01171 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LOPFHFCG_01172 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LOPFHFCG_01173 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
LOPFHFCG_01174 1.5e-22 pilT S Proteolipid membrane potential modulator
LOPFHFCG_01175 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
LOPFHFCG_01176 1.7e-88 norB G Major Facilitator Superfamily
LOPFHFCG_01177 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LOPFHFCG_01178 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LOPFHFCG_01179 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LOPFHFCG_01180 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LOPFHFCG_01181 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LOPFHFCG_01182 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
LOPFHFCG_01183 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LOPFHFCG_01184 9.5e-28 yjzC S YjzC-like protein
LOPFHFCG_01185 2.3e-16 yjzD S Protein of unknown function (DUF2929)
LOPFHFCG_01186 6.2e-142 yjaU I carboxylic ester hydrolase activity
LOPFHFCG_01187 7.3e-103 yjaV
LOPFHFCG_01188 1.1e-183 med S Transcriptional activator protein med
LOPFHFCG_01189 7.3e-26 comZ S ComZ
LOPFHFCG_01190 2.7e-22 yjzB
LOPFHFCG_01191 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LOPFHFCG_01192 2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LOPFHFCG_01193 3.9e-150 yjaZ O Zn-dependent protease
LOPFHFCG_01194 1.8e-184 appD P Belongs to the ABC transporter superfamily
LOPFHFCG_01195 6.5e-187 appF E Belongs to the ABC transporter superfamily
LOPFHFCG_01196 8.9e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
LOPFHFCG_01197 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOPFHFCG_01198 3e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOPFHFCG_01199 5e-147 yjbA S Belongs to the UPF0736 family
LOPFHFCG_01200 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LOPFHFCG_01201 0.0 oppA E ABC transporter substrate-binding protein
LOPFHFCG_01202 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOPFHFCG_01203 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOPFHFCG_01204 1.5e-197 oppD P Belongs to the ABC transporter superfamily
LOPFHFCG_01205 5.5e-172 oppF E Belongs to the ABC transporter superfamily
LOPFHFCG_01206 9.8e-212 yjbB EGP Major Facilitator Superfamily
LOPFHFCG_01207 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOPFHFCG_01208 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LOPFHFCG_01209 1.7e-111 yjbE P Integral membrane protein TerC family
LOPFHFCG_01210 1.2e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LOPFHFCG_01211 2.6e-219 yjbF S Competence protein
LOPFHFCG_01212 0.0 pepF E oligoendopeptidase F
LOPFHFCG_01213 1.8e-20
LOPFHFCG_01214 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LOPFHFCG_01215 3.7e-72 yjbI S Bacterial-like globin
LOPFHFCG_01216 3.5e-68 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LOPFHFCG_01217 1e-99 yjbK S protein conserved in bacteria
LOPFHFCG_01218 7.8e-61 yjbL S Belongs to the UPF0738 family
LOPFHFCG_01219 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
LOPFHFCG_01220 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LOPFHFCG_01221 9.9e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LOPFHFCG_01222 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LOPFHFCG_01223 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LOPFHFCG_01224 6.4e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LOPFHFCG_01225 1.3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
LOPFHFCG_01226 3.7e-215 thiO 1.4.3.19 E Glycine oxidase
LOPFHFCG_01227 4.4e-29 thiS H thiamine diphosphate biosynthetic process
LOPFHFCG_01228 6.5e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LOPFHFCG_01229 3.7e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LOPFHFCG_01230 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LOPFHFCG_01231 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LOPFHFCG_01232 2.2e-53 yjbX S Spore coat protein
LOPFHFCG_01233 4.4e-82 cotZ S Spore coat protein
LOPFHFCG_01234 7.6e-96 cotY S Spore coat protein Z
LOPFHFCG_01235 6.4e-77 cotX S Spore Coat Protein X and V domain
LOPFHFCG_01236 3e-32 cotW
LOPFHFCG_01237 2.3e-55 cotV S Spore Coat Protein X and V domain
LOPFHFCG_01238 8.7e-57 yjcA S Protein of unknown function (DUF1360)
LOPFHFCG_01241 2.9e-38 spoVIF S Stage VI sporulation protein F
LOPFHFCG_01242 0.0 yjcD 3.6.4.12 L DNA helicase
LOPFHFCG_01243 1.7e-38
LOPFHFCG_01244 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOPFHFCG_01245 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LOPFHFCG_01246 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
LOPFHFCG_01247 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LOPFHFCG_01248 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LOPFHFCG_01249 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
LOPFHFCG_01250 1.1e-212 yjcL S Protein of unknown function (DUF819)
LOPFHFCG_01253 2.1e-190 S Putative amidase domain
LOPFHFCG_01254 2.6e-44 yjcN
LOPFHFCG_01257 8.5e-81 L Transposase
LOPFHFCG_01258 1.6e-72 yjcP
LOPFHFCG_01259 4.1e-49 S YjcQ protein
LOPFHFCG_01260 1.1e-92 yqaS L DNA packaging
LOPFHFCG_01261 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
LOPFHFCG_01262 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
LOPFHFCG_01264 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
LOPFHFCG_01265 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
LOPFHFCG_01266 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
LOPFHFCG_01267 4.8e-51 yjdF S Protein of unknown function (DUF2992)
LOPFHFCG_01268 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
LOPFHFCG_01270 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LOPFHFCG_01271 4.2e-29 S Domain of unknown function (DUF4177)
LOPFHFCG_01272 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
LOPFHFCG_01273 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LOPFHFCG_01275 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
LOPFHFCG_01276 5.5e-83 S Protein of unknown function (DUF2690)
LOPFHFCG_01277 3.6e-21 yjfB S Putative motility protein
LOPFHFCG_01278 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
LOPFHFCG_01279 1.2e-45 T PhoQ Sensor
LOPFHFCG_01280 8.9e-104 yjgB S Domain of unknown function (DUF4309)
LOPFHFCG_01281 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LOPFHFCG_01282 4.3e-95 yjgD S Protein of unknown function (DUF1641)
LOPFHFCG_01283 8.7e-07 S Domain of unknown function (DUF4352)
LOPFHFCG_01284 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
LOPFHFCG_01286 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
LOPFHFCG_01287 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LOPFHFCG_01288 8.2e-30
LOPFHFCG_01289 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LOPFHFCG_01290 1.9e-122 ybbM S transport system, permease component
LOPFHFCG_01291 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
LOPFHFCG_01292 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
LOPFHFCG_01293 2.8e-93 yjlB S Cupin domain
LOPFHFCG_01294 7.1e-66 yjlC S Protein of unknown function (DUF1641)
LOPFHFCG_01295 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
LOPFHFCG_01296 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
LOPFHFCG_01297 5.8e-250 yjmB G symporter YjmB
LOPFHFCG_01298 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
LOPFHFCG_01299 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
LOPFHFCG_01300 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LOPFHFCG_01301 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_01302 3.7e-227 exuT G Sugar (and other) transporter
LOPFHFCG_01303 2.3e-184 exuR K transcriptional
LOPFHFCG_01304 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
LOPFHFCG_01305 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
LOPFHFCG_01306 4.3e-130 MA20_18170 S membrane transporter protein
LOPFHFCG_01307 3.3e-80 yjoA S DinB family
LOPFHFCG_01308 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
LOPFHFCG_01309 2.1e-213 S response regulator aspartate phosphatase
LOPFHFCG_01311 6.3e-41 S YCII-related domain
LOPFHFCG_01312 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
LOPFHFCG_01313 2.1e-61 yjqA S Bacterial PH domain
LOPFHFCG_01314 4.2e-112 yjqB S Pfam:DUF867
LOPFHFCG_01315 4.4e-160 ydbD P Catalase
LOPFHFCG_01316 1.6e-111 xkdA E IrrE N-terminal-like domain
LOPFHFCG_01317 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
LOPFHFCG_01319 5.9e-157 xkdB K sequence-specific DNA binding
LOPFHFCG_01320 6.4e-119 xkdC L Bacterial dnaA protein
LOPFHFCG_01323 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
LOPFHFCG_01324 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LOPFHFCG_01325 4.8e-140 xtmA L phage terminase small subunit
LOPFHFCG_01326 9.6e-255 xtmB S phage terminase, large subunit
LOPFHFCG_01327 5.4e-286 yqbA S portal protein
LOPFHFCG_01328 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
LOPFHFCG_01329 5.8e-169 xkdG S Phage capsid family
LOPFHFCG_01330 5.5e-65 yqbG S Protein of unknown function (DUF3199)
LOPFHFCG_01331 8.7e-65 yqbH S Domain of unknown function (DUF3599)
LOPFHFCG_01332 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
LOPFHFCG_01333 1.9e-77 xkdJ
LOPFHFCG_01334 2.5e-256 xkdK S Phage tail sheath C-terminal domain
LOPFHFCG_01335 6.1e-76 xkdM S Phage tail tube protein
LOPFHFCG_01336 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
LOPFHFCG_01337 0.0 xkdO L Transglycosylase SLT domain
LOPFHFCG_01338 3.7e-122 xkdP S Lysin motif
LOPFHFCG_01339 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
LOPFHFCG_01340 2.1e-39 xkdR S Protein of unknown function (DUF2577)
LOPFHFCG_01341 9.6e-71 xkdS S Protein of unknown function (DUF2634)
LOPFHFCG_01342 1.2e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LOPFHFCG_01343 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LOPFHFCG_01344 6.7e-41
LOPFHFCG_01345 0.0
LOPFHFCG_01346 2.6e-55 xkdW S XkdW protein
LOPFHFCG_01347 1.7e-23 xkdX
LOPFHFCG_01348 1.2e-154 xepA
LOPFHFCG_01349 2.8e-39 xhlA S Haemolysin XhlA
LOPFHFCG_01350 9.3e-40 xhlB S SPP1 phage holin
LOPFHFCG_01351 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOPFHFCG_01352 6.7e-23 spoIISB S Stage II sporulation protein SB
LOPFHFCG_01353 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
LOPFHFCG_01354 5.8e-175 pit P phosphate transporter
LOPFHFCG_01355 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
LOPFHFCG_01356 9.4e-242 steT E amino acid
LOPFHFCG_01357 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LOPFHFCG_01359 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LOPFHFCG_01360 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOPFHFCG_01362 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOPFHFCG_01363 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
LOPFHFCG_01364 7.9e-154 dppA E D-aminopeptidase
LOPFHFCG_01365 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOPFHFCG_01366 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LOPFHFCG_01367 3.4e-191 dppD P Belongs to the ABC transporter superfamily
LOPFHFCG_01368 0.0 dppE E ABC transporter substrate-binding protein
LOPFHFCG_01370 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LOPFHFCG_01371 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LOPFHFCG_01372 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LOPFHFCG_01373 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
LOPFHFCG_01374 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
LOPFHFCG_01375 5.3e-161 ykgA E Amidinotransferase
LOPFHFCG_01376 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
LOPFHFCG_01377 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LOPFHFCG_01378 1e-07
LOPFHFCG_01379 5.4e-130 ykjA S Protein of unknown function (DUF421)
LOPFHFCG_01380 1e-98 ykkA S Protein of unknown function (DUF664)
LOPFHFCG_01381 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LOPFHFCG_01382 3.5e-55 ykkC P Multidrug resistance protein
LOPFHFCG_01383 2.2e-48 ykkD P Multidrug resistance protein
LOPFHFCG_01384 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LOPFHFCG_01385 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LOPFHFCG_01386 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LOPFHFCG_01387 1.3e-70 ohrA O Organic hydroperoxide resistance protein
LOPFHFCG_01388 3.9e-75 ohrR K COG1846 Transcriptional regulators
LOPFHFCG_01389 8.4e-72 ohrB O Organic hydroperoxide resistance protein
LOPFHFCG_01391 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
LOPFHFCG_01392 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LOPFHFCG_01393 1.7e-176 isp O Belongs to the peptidase S8 family
LOPFHFCG_01394 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LOPFHFCG_01395 1.8e-136 ykoC P Cobalt transport protein
LOPFHFCG_01396 4.6e-311 P ABC transporter, ATP-binding protein
LOPFHFCG_01397 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
LOPFHFCG_01398 7.9e-111 ykoF S YKOF-related Family
LOPFHFCG_01399 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_01400 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
LOPFHFCG_01401 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
LOPFHFCG_01402 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
LOPFHFCG_01405 2.2e-222 mgtE P Acts as a magnesium transporter
LOPFHFCG_01406 1.4e-53 tnrA K transcriptional
LOPFHFCG_01407 5.9e-18
LOPFHFCG_01408 6.9e-26 ykoL
LOPFHFCG_01409 1.3e-81 mhqR K transcriptional
LOPFHFCG_01410 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
LOPFHFCG_01411 3.7e-99 ykoP G polysaccharide deacetylase
LOPFHFCG_01412 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
LOPFHFCG_01413 0.0 ykoS
LOPFHFCG_01414 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOPFHFCG_01415 2.3e-262 ligD 6.5.1.1 L ATP-dependent DNA ligase
LOPFHFCG_01416 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LOPFHFCG_01417 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
LOPFHFCG_01418 1.4e-116 ykoX S membrane-associated protein
LOPFHFCG_01419 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LOPFHFCG_01420 4.7e-129 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOPFHFCG_01421 8.2e-117 rsgI S Anti-sigma factor N-terminus
LOPFHFCG_01422 1.9e-26 sspD S small acid-soluble spore protein
LOPFHFCG_01423 1.5e-124 ykrK S Domain of unknown function (DUF1836)
LOPFHFCG_01424 7e-156 htpX O Belongs to the peptidase M48B family
LOPFHFCG_01425 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
LOPFHFCG_01426 1.2e-10 ydfR S Protein of unknown function (DUF421)
LOPFHFCG_01427 4.5e-22 ykzE
LOPFHFCG_01428 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
LOPFHFCG_01429 0.0 kinE 2.7.13.3 T Histidine kinase
LOPFHFCG_01430 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LOPFHFCG_01432 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LOPFHFCG_01433 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LOPFHFCG_01434 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LOPFHFCG_01435 8e-232 mtnE 2.6.1.83 E Aminotransferase
LOPFHFCG_01436 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LOPFHFCG_01437 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LOPFHFCG_01438 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LOPFHFCG_01439 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LOPFHFCG_01440 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
LOPFHFCG_01441 6.4e-09 S Spo0E like sporulation regulatory protein
LOPFHFCG_01442 1.4e-64 eag
LOPFHFCG_01443 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
LOPFHFCG_01444 1.3e-75 ykvE K transcriptional
LOPFHFCG_01445 2.5e-125 motB N Flagellar motor protein
LOPFHFCG_01446 2.7e-138 motA N flagellar motor
LOPFHFCG_01447 0.0 clpE O Belongs to the ClpA ClpB family
LOPFHFCG_01448 8.7e-182 ykvI S membrane
LOPFHFCG_01449 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LOPFHFCG_01450 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
LOPFHFCG_01451 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LOPFHFCG_01452 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LOPFHFCG_01453 2e-61 ykvN K Transcriptional regulator
LOPFHFCG_01454 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
LOPFHFCG_01455 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
LOPFHFCG_01456 1.2e-35 3.5.1.104 M LysM domain
LOPFHFCG_01457 8.5e-133 G Glycosyl hydrolases family 18
LOPFHFCG_01458 5.6e-46 ykvR S Protein of unknown function (DUF3219)
LOPFHFCG_01459 6e-25 ykvS S protein conserved in bacteria
LOPFHFCG_01460 2.8e-28
LOPFHFCG_01461 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
LOPFHFCG_01462 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOPFHFCG_01463 4.9e-90 stoA CO thiol-disulfide
LOPFHFCG_01464 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LOPFHFCG_01465 3.8e-09
LOPFHFCG_01466 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LOPFHFCG_01468 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
LOPFHFCG_01470 4.5e-128 glcT K antiterminator
LOPFHFCG_01471 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOPFHFCG_01472 2.1e-39 ptsH G phosphocarrier protein HPr
LOPFHFCG_01473 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LOPFHFCG_01474 7.2e-39 splA S Transcriptional regulator
LOPFHFCG_01475 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
LOPFHFCG_01476 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOPFHFCG_01477 2e-264 mcpC NT chemotaxis protein
LOPFHFCG_01478 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LOPFHFCG_01479 8e-124 ykwD J protein with SCP PR1 domains
LOPFHFCG_01480 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
LOPFHFCG_01481 0.0 pilS 2.7.13.3 T Histidine kinase
LOPFHFCG_01482 8e-224 patA 2.6.1.1 E Aminotransferase
LOPFHFCG_01483 2.2e-15
LOPFHFCG_01484 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
LOPFHFCG_01485 1.7e-84 ykyB S YkyB-like protein
LOPFHFCG_01486 1.6e-238 ykuC EGP Major facilitator Superfamily
LOPFHFCG_01487 4.6e-88 ykuD S protein conserved in bacteria
LOPFHFCG_01488 9.4e-166 ykuE S Metallophosphoesterase
LOPFHFCG_01489 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_01490 0.0 3.2.1.132 M Putative peptidoglycan binding domain
LOPFHFCG_01491 1.7e-93 M Peptidoglycan-binding domain 1 protein
LOPFHFCG_01493 5.2e-234 ykuI T Diguanylate phosphodiesterase
LOPFHFCG_01494 3.9e-37 ykuJ S protein conserved in bacteria
LOPFHFCG_01495 4.4e-94 ykuK S Ribonuclease H-like
LOPFHFCG_01496 3.9e-27 ykzF S Antirepressor AbbA
LOPFHFCG_01497 1.6e-76 ykuL S CBS domain
LOPFHFCG_01498 3.5e-168 ccpC K Transcriptional regulator
LOPFHFCG_01499 5.7e-88 fld C Flavodoxin domain
LOPFHFCG_01500 3.2e-177 ykuO
LOPFHFCG_01501 3.2e-80 fld C Flavodoxin
LOPFHFCG_01502 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LOPFHFCG_01503 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LOPFHFCG_01504 9e-37 ykuS S Belongs to the UPF0180 family
LOPFHFCG_01505 8.8e-142 ykuT M Mechanosensitive ion channel
LOPFHFCG_01506 3.9e-101 ykuU O Alkyl hydroperoxide reductase
LOPFHFCG_01507 4.4e-82 ykuV CO thiol-disulfide
LOPFHFCG_01508 5.8e-95 rok K Repressor of ComK
LOPFHFCG_01509 2.9e-147 yknT
LOPFHFCG_01510 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LOPFHFCG_01511 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LOPFHFCG_01512 8.1e-246 moeA 2.10.1.1 H molybdopterin
LOPFHFCG_01513 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LOPFHFCG_01514 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
LOPFHFCG_01515 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LOPFHFCG_01516 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOPFHFCG_01517 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
LOPFHFCG_01518 1e-117 yknW S Yip1 domain
LOPFHFCG_01519 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LOPFHFCG_01520 2.5e-124 macB V ABC transporter, ATP-binding protein
LOPFHFCG_01521 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
LOPFHFCG_01522 3.1e-136 fruR K Transcriptional regulator
LOPFHFCG_01523 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LOPFHFCG_01524 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LOPFHFCG_01525 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LOPFHFCG_01526 8.1e-39 ykoA
LOPFHFCG_01527 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LOPFHFCG_01528 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LOPFHFCG_01529 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LOPFHFCG_01530 1.1e-12 S Uncharacterized protein YkpC
LOPFHFCG_01531 7.7e-183 mreB D Rod-share determining protein MreBH
LOPFHFCG_01532 1.5e-43 abrB K of stationary sporulation gene expression
LOPFHFCG_01533 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
LOPFHFCG_01534 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
LOPFHFCG_01535 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
LOPFHFCG_01536 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LOPFHFCG_01537 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOPFHFCG_01538 8.2e-31 ykzG S Belongs to the UPF0356 family
LOPFHFCG_01539 1.4e-147 ykrA S hydrolases of the HAD superfamily
LOPFHFCG_01540 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LOPFHFCG_01542 2e-115 recN L Putative cell-wall binding lipoprotein
LOPFHFCG_01543 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LOPFHFCG_01544 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LOPFHFCG_01545 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LOPFHFCG_01546 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LOPFHFCG_01547 6.6e-60 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
LOPFHFCG_01548 3.5e-277 speA 4.1.1.19 E Arginine
LOPFHFCG_01549 1.6e-42 yktA S Belongs to the UPF0223 family
LOPFHFCG_01550 7.1e-118 yktB S Belongs to the UPF0637 family
LOPFHFCG_01551 7.1e-26 ykzI
LOPFHFCG_01552 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
LOPFHFCG_01553 6.9e-78 ykzC S Acetyltransferase (GNAT) family
LOPFHFCG_01554 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LOPFHFCG_01555 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
LOPFHFCG_01556 0.0 ylaA
LOPFHFCG_01557 2.7e-42 ylaB
LOPFHFCG_01558 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_01559 1.2e-11 sigC S Putative zinc-finger
LOPFHFCG_01560 1.8e-38 ylaE
LOPFHFCG_01561 8.2e-22 S Family of unknown function (DUF5325)
LOPFHFCG_01562 0.0 typA T GTP-binding protein TypA
LOPFHFCG_01563 4.2e-47 ylaH S YlaH-like protein
LOPFHFCG_01564 2.5e-32 ylaI S protein conserved in bacteria
LOPFHFCG_01565 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LOPFHFCG_01566 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
LOPFHFCG_01567 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LOPFHFCG_01568 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
LOPFHFCG_01569 8.7e-44 ylaN S Belongs to the UPF0358 family
LOPFHFCG_01570 4.5e-214 ftsW D Belongs to the SEDS family
LOPFHFCG_01571 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LOPFHFCG_01572 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LOPFHFCG_01573 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LOPFHFCG_01574 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LOPFHFCG_01575 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LOPFHFCG_01576 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LOPFHFCG_01577 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LOPFHFCG_01578 3e-167 ctaG S cytochrome c oxidase
LOPFHFCG_01579 7e-62 ylbA S YugN-like family
LOPFHFCG_01580 2.6e-74 ylbB T COG0517 FOG CBS domain
LOPFHFCG_01581 3e-201 ylbC S protein with SCP PR1 domains
LOPFHFCG_01582 4.1e-63 ylbD S Putative coat protein
LOPFHFCG_01583 6.7e-37 ylbE S YlbE-like protein
LOPFHFCG_01584 1.8e-75 ylbF S Belongs to the UPF0342 family
LOPFHFCG_01585 7.5e-39 ylbG S UPF0298 protein
LOPFHFCG_01586 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
LOPFHFCG_01587 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LOPFHFCG_01588 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
LOPFHFCG_01589 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
LOPFHFCG_01590 6.8e-187 ylbL T Belongs to the peptidase S16 family
LOPFHFCG_01591 2.8e-235 ylbM S Belongs to the UPF0348 family
LOPFHFCG_01593 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
LOPFHFCG_01594 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LOPFHFCG_01595 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LOPFHFCG_01596 4e-89 ylbP K n-acetyltransferase
LOPFHFCG_01597 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LOPFHFCG_01598 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LOPFHFCG_01599 2.9e-78 mraZ K Belongs to the MraZ family
LOPFHFCG_01600 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LOPFHFCG_01601 3.7e-44 ftsL D Essential cell division protein
LOPFHFCG_01602 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LOPFHFCG_01603 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
LOPFHFCG_01604 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LOPFHFCG_01605 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LOPFHFCG_01606 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LOPFHFCG_01607 5.7e-186 spoVE D Belongs to the SEDS family
LOPFHFCG_01608 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LOPFHFCG_01609 5.3e-167 murB 1.3.1.98 M cell wall formation
LOPFHFCG_01610 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LOPFHFCG_01611 2.4e-103 ylxW S protein conserved in bacteria
LOPFHFCG_01612 1e-102 ylxX S protein conserved in bacteria
LOPFHFCG_01613 6.2e-58 sbp S small basic protein
LOPFHFCG_01614 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LOPFHFCG_01615 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LOPFHFCG_01616 0.0 bpr O COG1404 Subtilisin-like serine proteases
LOPFHFCG_01617 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LOPFHFCG_01618 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOPFHFCG_01619 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOPFHFCG_01620 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LOPFHFCG_01621 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
LOPFHFCG_01622 2.4e-37 ylmC S sporulation protein
LOPFHFCG_01623 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LOPFHFCG_01624 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LOPFHFCG_01625 3.3e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LOPFHFCG_01626 1.3e-39 yggT S membrane
LOPFHFCG_01627 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LOPFHFCG_01628 2.6e-67 divIVA D Cell division initiation protein
LOPFHFCG_01629 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LOPFHFCG_01630 1.3e-63 dksA T COG1734 DnaK suppressor protein
LOPFHFCG_01631 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LOPFHFCG_01632 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LOPFHFCG_01633 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LOPFHFCG_01634 9e-232 pyrP F Xanthine uracil
LOPFHFCG_01635 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LOPFHFCG_01636 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LOPFHFCG_01637 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LOPFHFCG_01638 0.0 carB 6.3.5.5 F Belongs to the CarB family
LOPFHFCG_01639 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LOPFHFCG_01640 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LOPFHFCG_01641 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LOPFHFCG_01642 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LOPFHFCG_01644 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LOPFHFCG_01645 1.1e-179 cysP P phosphate transporter
LOPFHFCG_01646 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LOPFHFCG_01647 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
LOPFHFCG_01648 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LOPFHFCG_01649 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
LOPFHFCG_01650 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
LOPFHFCG_01651 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LOPFHFCG_01652 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
LOPFHFCG_01653 2.4e-156 yloC S stress-induced protein
LOPFHFCG_01654 1.5e-40 ylzA S Belongs to the UPF0296 family
LOPFHFCG_01655 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LOPFHFCG_01656 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LOPFHFCG_01657 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LOPFHFCG_01658 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LOPFHFCG_01659 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LOPFHFCG_01660 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LOPFHFCG_01661 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LOPFHFCG_01662 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LOPFHFCG_01663 2.4e-141 stp 3.1.3.16 T phosphatase
LOPFHFCG_01664 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LOPFHFCG_01665 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LOPFHFCG_01666 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LOPFHFCG_01667 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
LOPFHFCG_01668 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LOPFHFCG_01669 5.5e-59 asp S protein conserved in bacteria
LOPFHFCG_01670 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
LOPFHFCG_01671 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
LOPFHFCG_01672 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
LOPFHFCG_01673 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LOPFHFCG_01674 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LOPFHFCG_01675 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LOPFHFCG_01676 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LOPFHFCG_01677 6.1e-129 IQ reductase
LOPFHFCG_01678 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LOPFHFCG_01679 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LOPFHFCG_01680 0.0 smc D Required for chromosome condensation and partitioning
LOPFHFCG_01681 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LOPFHFCG_01682 2.9e-87
LOPFHFCG_01683 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LOPFHFCG_01684 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LOPFHFCG_01685 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LOPFHFCG_01686 1.2e-36 ylqC S Belongs to the UPF0109 family
LOPFHFCG_01687 1.3e-61 ylqD S YlqD protein
LOPFHFCG_01688 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LOPFHFCG_01689 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LOPFHFCG_01690 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LOPFHFCG_01691 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LOPFHFCG_01692 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LOPFHFCG_01693 8.5e-291 ylqG
LOPFHFCG_01694 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
LOPFHFCG_01695 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LOPFHFCG_01696 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LOPFHFCG_01697 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LOPFHFCG_01698 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LOPFHFCG_01699 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LOPFHFCG_01700 2.5e-169 xerC L tyrosine recombinase XerC
LOPFHFCG_01701 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LOPFHFCG_01702 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LOPFHFCG_01703 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LOPFHFCG_01704 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LOPFHFCG_01705 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
LOPFHFCG_01706 1.9e-31 fliE N Flagellar hook-basal body
LOPFHFCG_01707 2.4e-255 fliF N The M ring may be actively involved in energy transduction
LOPFHFCG_01708 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LOPFHFCG_01709 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
LOPFHFCG_01710 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LOPFHFCG_01711 1.5e-69 fliJ N Flagellar biosynthesis chaperone
LOPFHFCG_01712 7.7e-37 ylxF S MgtE intracellular N domain
LOPFHFCG_01713 1.2e-221 fliK N Flagellar hook-length control protein
LOPFHFCG_01714 1.7e-72 flgD N Flagellar basal body rod modification protein
LOPFHFCG_01715 8.2e-140 flgG N Flagellar basal body rod
LOPFHFCG_01716 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
LOPFHFCG_01717 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LOPFHFCG_01718 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LOPFHFCG_01719 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
LOPFHFCG_01720 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
LOPFHFCG_01721 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
LOPFHFCG_01722 2.2e-36 fliQ N Role in flagellar biosynthesis
LOPFHFCG_01723 3.6e-132 fliR N Flagellar biosynthetic protein FliR
LOPFHFCG_01724 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LOPFHFCG_01725 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LOPFHFCG_01726 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
LOPFHFCG_01727 7.5e-158 flhG D Belongs to the ParA family
LOPFHFCG_01728 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LOPFHFCG_01729 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
LOPFHFCG_01730 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
LOPFHFCG_01731 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LOPFHFCG_01732 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LOPFHFCG_01733 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOPFHFCG_01734 4.3e-78 ylxL
LOPFHFCG_01735 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
LOPFHFCG_01736 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LOPFHFCG_01737 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LOPFHFCG_01738 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LOPFHFCG_01739 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LOPFHFCG_01740 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
LOPFHFCG_01741 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LOPFHFCG_01742 7.7e-233 rasP M zinc metalloprotease
LOPFHFCG_01743 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LOPFHFCG_01744 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LOPFHFCG_01745 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
LOPFHFCG_01746 7.3e-203 nusA K Participates in both transcription termination and antitermination
LOPFHFCG_01747 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
LOPFHFCG_01748 3.1e-47 ylxQ J ribosomal protein
LOPFHFCG_01749 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LOPFHFCG_01750 3e-44 ylxP S protein conserved in bacteria
LOPFHFCG_01751 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LOPFHFCG_01752 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LOPFHFCG_01753 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LOPFHFCG_01754 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LOPFHFCG_01755 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LOPFHFCG_01756 3.2e-172 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
LOPFHFCG_01757 4.4e-233 pepR S Belongs to the peptidase M16 family
LOPFHFCG_01758 2.6e-42 ymxH S YlmC YmxH family
LOPFHFCG_01759 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
LOPFHFCG_01760 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LOPFHFCG_01761 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LOPFHFCG_01762 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LOPFHFCG_01763 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LOPFHFCG_01764 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LOPFHFCG_01765 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
LOPFHFCG_01766 4.4e-32 S YlzJ-like protein
LOPFHFCG_01767 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LOPFHFCG_01768 1.4e-133 ymfC K Transcriptional regulator
LOPFHFCG_01769 3.4e-206 ymfD EGP Major facilitator Superfamily
LOPFHFCG_01770 2.6e-236 ymfF S Peptidase M16
LOPFHFCG_01771 1.4e-242 ymfH S zinc protease
LOPFHFCG_01772 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LOPFHFCG_01773 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
LOPFHFCG_01774 2.4e-76 ymfK S Protein of unknown function (DUF3388)
LOPFHFCG_01775 3.1e-53 ymfK S Protein of unknown function (DUF3388)
LOPFHFCG_01776 1.9e-124 ymfM S protein conserved in bacteria
LOPFHFCG_01777 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LOPFHFCG_01778 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
LOPFHFCG_01779 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LOPFHFCG_01780 1e-215 pbpX V Beta-lactamase
LOPFHFCG_01781 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
LOPFHFCG_01782 1.9e-152 ymdB S protein conserved in bacteria
LOPFHFCG_01783 1.2e-36 spoVS S Stage V sporulation protein S
LOPFHFCG_01784 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LOPFHFCG_01785 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LOPFHFCG_01786 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LOPFHFCG_01787 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LOPFHFCG_01788 2.2e-88 cotE S Spore coat protein
LOPFHFCG_01789 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LOPFHFCG_01790 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LOPFHFCG_01791 2.3e-70 S Regulatory protein YrvL
LOPFHFCG_01793 1.2e-97 ymcC S Membrane
LOPFHFCG_01794 4.4e-109 pksA K Transcriptional regulator
LOPFHFCG_01795 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
LOPFHFCG_01796 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LOPFHFCG_01798 2.4e-186 pksD Q Acyl transferase domain
LOPFHFCG_01799 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LOPFHFCG_01800 1.4e-37 acpK IQ Phosphopantetheine attachment site
LOPFHFCG_01801 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LOPFHFCG_01802 1.3e-245 pksG 2.3.3.10 I synthase
LOPFHFCG_01803 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
LOPFHFCG_01804 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
LOPFHFCG_01805 0.0 rhiB IQ polyketide synthase
LOPFHFCG_01806 0.0 pfaA Q Polyketide synthase of type I
LOPFHFCG_01807 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
LOPFHFCG_01808 0.0 dhbF IQ polyketide synthase
LOPFHFCG_01809 0.0 dhbF IQ polyketide synthase
LOPFHFCG_01810 0.0 pks13 HQ Beta-ketoacyl synthase
LOPFHFCG_01811 2.5e-233 cypA C Cytochrome P450
LOPFHFCG_01812 1.2e-61 ymzB
LOPFHFCG_01813 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
LOPFHFCG_01814 4.6e-252 aprX O Belongs to the peptidase S8 family
LOPFHFCG_01815 2.1e-126 ymaC S Replication protein
LOPFHFCG_01816 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
LOPFHFCG_01817 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
LOPFHFCG_01818 4.9e-51 ebrA P Small Multidrug Resistance protein
LOPFHFCG_01820 2.1e-46 ymaF S YmaF family
LOPFHFCG_01821 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LOPFHFCG_01822 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LOPFHFCG_01823 6.3e-23
LOPFHFCG_01824 4.5e-22 ymzA
LOPFHFCG_01825 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LOPFHFCG_01826 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOPFHFCG_01827 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOPFHFCG_01828 2e-109 ymaB
LOPFHFCG_01829 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOPFHFCG_01830 1.7e-176 spoVK O stage V sporulation protein K
LOPFHFCG_01831 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LOPFHFCG_01832 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LOPFHFCG_01833 1.1e-68 glnR K transcriptional
LOPFHFCG_01834 7e-261 glnA 6.3.1.2 E glutamine synthetase
LOPFHFCG_01835 5e-10
LOPFHFCG_01836 2.5e-32
LOPFHFCG_01837 5.8e-39
LOPFHFCG_01838 6.8e-80 G regulation of fungal-type cell wall biogenesis
LOPFHFCG_01839 4.9e-145 ynaC
LOPFHFCG_01840 2e-99 ynaD J Acetyltransferase (GNAT) domain
LOPFHFCG_01841 1.9e-123 ynaE S Domain of unknown function (DUF3885)
LOPFHFCG_01842 6.4e-60 ynaF
LOPFHFCG_01845 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
LOPFHFCG_01846 2.7e-255 xynT G MFS/sugar transport protein
LOPFHFCG_01847 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
LOPFHFCG_01848 1e-215 xylR GK ROK family
LOPFHFCG_01849 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
LOPFHFCG_01850 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
LOPFHFCG_01851 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
LOPFHFCG_01852 3.5e-247 iolT EGP Major facilitator Superfamily
LOPFHFCG_01853 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LOPFHFCG_01854 6.3e-84 yncE S Protein of unknown function (DUF2691)
LOPFHFCG_01855 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LOPFHFCG_01856 5.2e-15
LOPFHFCG_01859 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LOPFHFCG_01861 1.3e-134 S Domain of unknown function, YrpD
LOPFHFCG_01864 7.9e-25 tatA U protein secretion
LOPFHFCG_01865 1.8e-71
LOPFHFCG_01866 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
LOPFHFCG_01869 5.7e-286 gerAA EG Spore germination protein
LOPFHFCG_01870 4.5e-197 gerAB U Spore germination
LOPFHFCG_01871 4.2e-220 gerLC S Spore germination protein
LOPFHFCG_01872 7.7e-154 yndG S DoxX-like family
LOPFHFCG_01873 2.6e-117 yndH S Domain of unknown function (DUF4166)
LOPFHFCG_01874 0.0 yndJ S YndJ-like protein
LOPFHFCG_01876 8.6e-139 yndL S Replication protein
LOPFHFCG_01877 5.8e-74 yndM S Protein of unknown function (DUF2512)
LOPFHFCG_01878 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LOPFHFCG_01880 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LOPFHFCG_01881 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LOPFHFCG_01882 9.2e-113 yneB L resolvase
LOPFHFCG_01883 1.3e-32 ynzC S UPF0291 protein
LOPFHFCG_01884 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LOPFHFCG_01885 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
LOPFHFCG_01886 1.8e-28 yneF S UPF0154 protein
LOPFHFCG_01887 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
LOPFHFCG_01888 7.1e-127 ccdA O cytochrome c biogenesis protein
LOPFHFCG_01889 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
LOPFHFCG_01890 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LOPFHFCG_01891 4.2e-74 yneK S Protein of unknown function (DUF2621)
LOPFHFCG_01892 1.2e-64 hspX O Spore coat protein
LOPFHFCG_01893 3.9e-19 sspP S Belongs to the SspP family
LOPFHFCG_01894 2.2e-14 sspO S Belongs to the SspO family
LOPFHFCG_01895 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LOPFHFCG_01896 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LOPFHFCG_01898 3.1e-08 sspN S Small acid-soluble spore protein N family
LOPFHFCG_01899 3.9e-35 tlp S Belongs to the Tlp family
LOPFHFCG_01900 2e-73 yneP S Thioesterase-like superfamily
LOPFHFCG_01901 1.7e-53 yneQ
LOPFHFCG_01902 4.1e-49 yneR S Belongs to the HesB IscA family
LOPFHFCG_01903 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LOPFHFCG_01904 8.6e-69 yccU S CoA-binding protein
LOPFHFCG_01905 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LOPFHFCG_01906 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LOPFHFCG_01907 2.3e-12
LOPFHFCG_01908 8.6e-57 ynfC
LOPFHFCG_01909 5.3e-251 agcS E Sodium alanine symporter
LOPFHFCG_01910 1.7e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
LOPFHFCG_01912 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
LOPFHFCG_01913 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
LOPFHFCG_01914 2.4e-80 yngA S membrane
LOPFHFCG_01915 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LOPFHFCG_01916 5.5e-104 yngC S membrane-associated protein
LOPFHFCG_01917 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
LOPFHFCG_01918 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LOPFHFCG_01919 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LOPFHFCG_01920 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
LOPFHFCG_01921 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
LOPFHFCG_01922 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
LOPFHFCG_01923 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LOPFHFCG_01924 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
LOPFHFCG_01925 1.8e-31 S Family of unknown function (DUF5367)
LOPFHFCG_01926 1.3e-306 yngK T Glycosyl hydrolase-like 10
LOPFHFCG_01927 2.8e-64 yngL S Protein of unknown function (DUF1360)
LOPFHFCG_01928 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
LOPFHFCG_01929 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_01930 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_01931 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_01932 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_01933 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LOPFHFCG_01934 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
LOPFHFCG_01935 2.3e-246 yoeA V MATE efflux family protein
LOPFHFCG_01936 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
LOPFHFCG_01938 2.2e-96 L Integrase
LOPFHFCG_01939 3e-34 yoeD G Helix-turn-helix domain
LOPFHFCG_01940 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LOPFHFCG_01941 2.5e-158 gltR1 K Transcriptional regulator
LOPFHFCG_01942 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LOPFHFCG_01943 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LOPFHFCG_01944 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
LOPFHFCG_01945 7.8e-155 gltC K Transcriptional regulator
LOPFHFCG_01946 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LOPFHFCG_01947 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOPFHFCG_01948 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LOPFHFCG_01949 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_01950 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
LOPFHFCG_01951 3.1e-144 yoxB
LOPFHFCG_01952 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LOPFHFCG_01953 6.2e-235 yoaB EGP Major facilitator Superfamily
LOPFHFCG_01954 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
LOPFHFCG_01955 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOPFHFCG_01956 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOPFHFCG_01957 1.9e-33 yoaF
LOPFHFCG_01958 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
LOPFHFCG_01959 7e-14
LOPFHFCG_01960 1.5e-38 S Protein of unknown function (DUF4025)
LOPFHFCG_01961 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
LOPFHFCG_01962 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
LOPFHFCG_01963 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
LOPFHFCG_01964 2.3e-111 yoaK S Membrane
LOPFHFCG_01965 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
LOPFHFCG_01966 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
LOPFHFCG_01968 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
LOPFHFCG_01970 1.5e-146 yoaP 3.1.3.18 K YoaP-like
LOPFHFCG_01971 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
LOPFHFCG_01972 4.1e-89
LOPFHFCG_01973 2.4e-172 yoaR V vancomycin resistance protein
LOPFHFCG_01974 4.3e-75 yoaS S Protein of unknown function (DUF2975)
LOPFHFCG_01975 4.2e-37 yozG K Transcriptional regulator
LOPFHFCG_01976 1.1e-149 yoaT S Protein of unknown function (DUF817)
LOPFHFCG_01977 8.6e-159 yoaU K LysR substrate binding domain
LOPFHFCG_01978 6e-160 yijE EG EamA-like transporter family
LOPFHFCG_01979 3.7e-78 yoaW
LOPFHFCG_01980 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LOPFHFCG_01981 2.3e-170 bla 3.5.2.6 V beta-lactamase
LOPFHFCG_01985 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LOPFHFCG_01986 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
LOPFHFCG_01987 1.4e-37 S TM2 domain
LOPFHFCG_01988 5.7e-58 K Helix-turn-helix
LOPFHFCG_01990 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
LOPFHFCG_01991 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
LOPFHFCG_01992 1.8e-178 yobF
LOPFHFCG_01997 1.7e-207 S aspartate phosphatase
LOPFHFCG_01999 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOPFHFCG_02000 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOPFHFCG_02001 2.6e-38 S YolD-like protein
LOPFHFCG_02002 1.2e-49
LOPFHFCG_02003 0.0 K Psort location Cytoplasmic, score
LOPFHFCG_02004 2.7e-157 yobJ
LOPFHFCG_02005 3e-86 S SMI1-KNR4 cell-wall
LOPFHFCG_02006 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LOPFHFCG_02007 7.9e-105 yokH G SMI1 / KNR4 family
LOPFHFCG_02008 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
LOPFHFCG_02009 0.0 yobO M Pectate lyase superfamily protein
LOPFHFCG_02010 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
LOPFHFCG_02011 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
LOPFHFCG_02012 2.5e-143 yobR 2.3.1.1 J FR47-like protein
LOPFHFCG_02013 3e-99 yobS K Transcriptional regulator
LOPFHFCG_02014 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
LOPFHFCG_02015 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
LOPFHFCG_02016 9e-178 yobV K WYL domain
LOPFHFCG_02017 2.5e-95 yobW
LOPFHFCG_02018 1e-51 czrA K transcriptional
LOPFHFCG_02019 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LOPFHFCG_02020 1.5e-92 yozB S membrane
LOPFHFCG_02021 2.2e-145
LOPFHFCG_02022 1.9e-94 yocC
LOPFHFCG_02023 6.9e-189 yocD 3.4.17.13 V peptidase S66
LOPFHFCG_02024 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LOPFHFCG_02025 3.2e-198 desK 2.7.13.3 T Histidine kinase
LOPFHFCG_02026 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOPFHFCG_02027 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
LOPFHFCG_02028 0.0 recQ 3.6.4.12 L DNA helicase
LOPFHFCG_02029 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LOPFHFCG_02030 3.3e-83 dksA T general stress protein
LOPFHFCG_02031 6.4e-54 yocL
LOPFHFCG_02032 6.6e-34
LOPFHFCG_02033 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
LOPFHFCG_02034 1.1e-40 yozN
LOPFHFCG_02035 1.9e-36 yocN
LOPFHFCG_02036 4.2e-56 yozO S Bacterial PH domain
LOPFHFCG_02037 2.7e-31 yozC
LOPFHFCG_02038 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
LOPFHFCG_02039 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
LOPFHFCG_02040 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
LOPFHFCG_02041 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LOPFHFCG_02042 5.1e-168 yocS S -transporter
LOPFHFCG_02043 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LOPFHFCG_02044 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LOPFHFCG_02045 0.0 yojO P Von Willebrand factor
LOPFHFCG_02046 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
LOPFHFCG_02047 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LOPFHFCG_02048 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LOPFHFCG_02049 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
LOPFHFCG_02050 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LOPFHFCG_02052 4.2e-245 norM V Multidrug efflux pump
LOPFHFCG_02053 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LOPFHFCG_02054 2.1e-125 yojG S deacetylase
LOPFHFCG_02055 2.2e-60 yojF S Protein of unknown function (DUF1806)
LOPFHFCG_02056 1.5e-43
LOPFHFCG_02057 3.5e-163 rarD S -transporter
LOPFHFCG_02058 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
LOPFHFCG_02059 3.4e-09
LOPFHFCG_02060 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
LOPFHFCG_02061 3.8e-66 yodA S tautomerase
LOPFHFCG_02062 1.7e-57 yodB K transcriptional
LOPFHFCG_02063 4.8e-108 yodC C nitroreductase
LOPFHFCG_02064 3.8e-113 mhqD S Carboxylesterase
LOPFHFCG_02065 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
LOPFHFCG_02066 6.2e-28 S Protein of unknown function (DUF3311)
LOPFHFCG_02067 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOPFHFCG_02068 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LOPFHFCG_02069 1.7e-128 yodH Q Methyltransferase
LOPFHFCG_02070 5.2e-24 yodI
LOPFHFCG_02071 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LOPFHFCG_02072 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LOPFHFCG_02073 5.3e-09
LOPFHFCG_02074 3.6e-54 yodL S YodL-like
LOPFHFCG_02075 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
LOPFHFCG_02076 2.8e-24 yozD S YozD-like protein
LOPFHFCG_02078 1.4e-124 yodN
LOPFHFCG_02079 1.4e-36 yozE S Belongs to the UPF0346 family
LOPFHFCG_02080 2.9e-47 yokU S YokU-like protein, putative antitoxin
LOPFHFCG_02081 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
LOPFHFCG_02082 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
LOPFHFCG_02083 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
LOPFHFCG_02084 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LOPFHFCG_02085 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LOPFHFCG_02086 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LOPFHFCG_02089 2.9e-145 yiiD K acetyltransferase
LOPFHFCG_02090 1e-256 cgeD M maturation of the outermost layer of the spore
LOPFHFCG_02091 3.5e-38 cgeC
LOPFHFCG_02092 1.2e-65 cgeA
LOPFHFCG_02093 3.3e-188 cgeB S Spore maturation protein
LOPFHFCG_02094 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
LOPFHFCG_02095 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
LOPFHFCG_02097 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LOPFHFCG_02098 1.4e-10 K Cro/C1-type HTH DNA-binding domain
LOPFHFCG_02106 1.9e-168 S Calcineurin-like phosphoesterase
LOPFHFCG_02107 2.5e-30 sspB S spore protein
LOPFHFCG_02112 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
LOPFHFCG_02113 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LOPFHFCG_02114 6.1e-38 O Glutaredoxin
LOPFHFCG_02115 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOPFHFCG_02116 3.3e-97 L HNH endonuclease
LOPFHFCG_02117 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOPFHFCG_02118 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOPFHFCG_02119 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LOPFHFCG_02120 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LOPFHFCG_02137 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
LOPFHFCG_02139 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
LOPFHFCG_02140 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
LOPFHFCG_02145 9.9e-115 DR0488 S protein conserved in bacteria
LOPFHFCG_02146 0.0 2.7.7.7 L DNA polymerase
LOPFHFCG_02147 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LOPFHFCG_02148 1.2e-224 L DNA primase activity
LOPFHFCG_02149 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
LOPFHFCG_02150 1.4e-86
LOPFHFCG_02151 7.6e-180 L AAA domain
LOPFHFCG_02152 1.3e-170
LOPFHFCG_02157 0.0 M Parallel beta-helix repeats
LOPFHFCG_02158 7.7e-149 S Pfam:DUF867
LOPFHFCG_02161 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
LOPFHFCG_02162 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
LOPFHFCG_02163 2.3e-77
LOPFHFCG_02170 1e-44
LOPFHFCG_02172 1.5e-97 S Protein of unknown function (DUF1273)
LOPFHFCG_02174 3e-78 yoqH M LysM domain
LOPFHFCG_02177 8.8e-12 S Protein of unknown function (DUF2815)
LOPFHFCG_02178 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
LOPFHFCG_02189 1.1e-33 K Transcriptional regulator
LOPFHFCG_02190 2.1e-177
LOPFHFCG_02191 6e-263 S DNA-sulfur modification-associated
LOPFHFCG_02192 6.8e-198 L Belongs to the 'phage' integrase family
LOPFHFCG_02197 6.6e-106
LOPFHFCG_02199 1.2e-86
LOPFHFCG_02200 1.1e-96 S Super-infection exclusion protein B
LOPFHFCG_02205 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
LOPFHFCG_02206 3.8e-259
LOPFHFCG_02207 4.6e-35 K Cro/C1-type HTH DNA-binding domain
LOPFHFCG_02208 1.4e-256
LOPFHFCG_02210 5.9e-238
LOPFHFCG_02212 4e-17
LOPFHFCG_02213 5.7e-55 bldD K domain, Protein
LOPFHFCG_02216 0.0
LOPFHFCG_02217 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LOPFHFCG_02219 2.6e-230
LOPFHFCG_02222 1.8e-175
LOPFHFCG_02223 0.0 gp17a S Terminase-like family
LOPFHFCG_02224 6.3e-282
LOPFHFCG_02225 2.1e-266
LOPFHFCG_02226 1.6e-94
LOPFHFCG_02227 5.7e-186
LOPFHFCG_02228 5.1e-81
LOPFHFCG_02229 1.1e-68
LOPFHFCG_02231 1.4e-121
LOPFHFCG_02232 2.6e-91
LOPFHFCG_02233 8.1e-131
LOPFHFCG_02234 1.6e-90
LOPFHFCG_02237 1.3e-57
LOPFHFCG_02238 1.1e-172
LOPFHFCG_02239 8.1e-07
LOPFHFCG_02240 2.5e-10 xkdX
LOPFHFCG_02241 2.5e-86
LOPFHFCG_02242 6.3e-70
LOPFHFCG_02243 2.1e-193 xerH A Belongs to the 'phage' integrase family
LOPFHFCG_02248 9.3e-116
LOPFHFCG_02249 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LOPFHFCG_02250 6.2e-145 S Phage tail protein
LOPFHFCG_02251 0.0 S Pfam Transposase IS66
LOPFHFCG_02252 6.4e-115
LOPFHFCG_02253 0.0 G Exopolysaccharide biosynthesis protein
LOPFHFCG_02254 6.5e-164
LOPFHFCG_02256 1.6e-186 3.5.1.28 M Ami_2
LOPFHFCG_02257 4.4e-32 bhlA S BhlA holin family
LOPFHFCG_02258 5.5e-40 S SPP1 phage holin
LOPFHFCG_02259 3.4e-74 O protein disulfide oxidoreductase activity
LOPFHFCG_02260 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOPFHFCG_02261 1.2e-70 CO cell redox homeostasis
LOPFHFCG_02262 0.0 V Peptidase C39 family
LOPFHFCG_02265 1.9e-239 S impB/mucB/samB family C-terminal domain
LOPFHFCG_02266 5.8e-55 S YolD-like protein
LOPFHFCG_02267 1.3e-37
LOPFHFCG_02269 6.8e-09 S Domain of unknown function (DUF4879)
LOPFHFCG_02271 2.8e-99 J Acetyltransferase (GNAT) domain
LOPFHFCG_02272 3.2e-109 yokK S SMI1 / KNR4 family
LOPFHFCG_02273 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
LOPFHFCG_02274 1.2e-302 UW nuclease activity
LOPFHFCG_02275 6.7e-92 yokH G SMI1 / KNR4 family
LOPFHFCG_02276 4.1e-203
LOPFHFCG_02277 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
LOPFHFCG_02278 1.1e-83 S Bacterial PH domain
LOPFHFCG_02279 8.4e-156 aacC 2.3.1.81 V aminoglycoside
LOPFHFCG_02282 8.9e-95
LOPFHFCG_02283 1.6e-107
LOPFHFCG_02284 2.7e-307 yokA L Recombinase
LOPFHFCG_02285 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
LOPFHFCG_02286 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LOPFHFCG_02287 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LOPFHFCG_02288 1.6e-70 ypoP K transcriptional
LOPFHFCG_02289 2.6e-223 mepA V MATE efflux family protein
LOPFHFCG_02290 5.5e-29 ypmT S Uncharacterized ympT
LOPFHFCG_02291 5e-99 ypmS S protein conserved in bacteria
LOPFHFCG_02292 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
LOPFHFCG_02293 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LOPFHFCG_02294 3.1e-40 ypmP S Protein of unknown function (DUF2535)
LOPFHFCG_02295 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LOPFHFCG_02296 1.6e-185 pspF K Transcriptional regulator
LOPFHFCG_02297 4.2e-110 hlyIII S protein, Hemolysin III
LOPFHFCG_02298 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LOPFHFCG_02299 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LOPFHFCG_02300 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LOPFHFCG_02301 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LOPFHFCG_02302 7.8e-114 ypjP S YpjP-like protein
LOPFHFCG_02303 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
LOPFHFCG_02304 1.7e-75 yphP S Belongs to the UPF0403 family
LOPFHFCG_02305 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LOPFHFCG_02306 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
LOPFHFCG_02307 3.1e-110 ypgQ S phosphohydrolase
LOPFHFCG_02308 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LOPFHFCG_02309 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LOPFHFCG_02310 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LOPFHFCG_02311 7.9e-31 cspD K Cold-shock protein
LOPFHFCG_02312 3.8e-16 degR
LOPFHFCG_02313 8.1e-31 S Protein of unknown function (DUF2564)
LOPFHFCG_02314 2.6e-27 ypeQ S Zinc-finger
LOPFHFCG_02315 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
LOPFHFCG_02316 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LOPFHFCG_02317 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
LOPFHFCG_02319 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
LOPFHFCG_02320 2e-07
LOPFHFCG_02321 1e-38 ypbS S Protein of unknown function (DUF2533)
LOPFHFCG_02322 0.0 ypbR S Dynamin family
LOPFHFCG_02323 5.1e-87 ypbQ S protein conserved in bacteria
LOPFHFCG_02324 4.4e-208 bcsA Q Naringenin-chalcone synthase
LOPFHFCG_02325 1.6e-228 pbuX F xanthine
LOPFHFCG_02326 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LOPFHFCG_02327 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LOPFHFCG_02328 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
LOPFHFCG_02329 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
LOPFHFCG_02330 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LOPFHFCG_02331 3.9e-187 ptxS K transcriptional
LOPFHFCG_02332 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LOPFHFCG_02333 5.6e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_02334 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
LOPFHFCG_02336 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LOPFHFCG_02337 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LOPFHFCG_02338 3.3e-92 ypsA S Belongs to the UPF0398 family
LOPFHFCG_02339 1.3e-237 yprB L RNase_H superfamily
LOPFHFCG_02340 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LOPFHFCG_02341 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
LOPFHFCG_02342 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
LOPFHFCG_02343 1.2e-48 yppG S YppG-like protein
LOPFHFCG_02345 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
LOPFHFCG_02348 2.6e-188 yppC S Protein of unknown function (DUF2515)
LOPFHFCG_02349 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LOPFHFCG_02350 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
LOPFHFCG_02351 4.7e-93 ypoC
LOPFHFCG_02352 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LOPFHFCG_02353 5.7e-129 dnaD L DNA replication protein DnaD
LOPFHFCG_02354 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
LOPFHFCG_02355 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LOPFHFCG_02356 3.4e-80 ypmB S protein conserved in bacteria
LOPFHFCG_02357 6.7e-23 ypmA S Protein of unknown function (DUF4264)
LOPFHFCG_02358 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LOPFHFCG_02359 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LOPFHFCG_02360 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LOPFHFCG_02361 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LOPFHFCG_02362 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LOPFHFCG_02363 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LOPFHFCG_02364 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
LOPFHFCG_02365 6.9e-130 bshB1 S proteins, LmbE homologs
LOPFHFCG_02366 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
LOPFHFCG_02367 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LOPFHFCG_02368 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
LOPFHFCG_02369 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
LOPFHFCG_02370 6.1e-143 ypjB S sporulation protein
LOPFHFCG_02371 4.4e-98 ypjA S membrane
LOPFHFCG_02372 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
LOPFHFCG_02373 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
LOPFHFCG_02374 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
LOPFHFCG_02375 8.5e-78 ypiF S Protein of unknown function (DUF2487)
LOPFHFCG_02376 2.8e-99 ypiB S Belongs to the UPF0302 family
LOPFHFCG_02377 4.1e-234 S COG0457 FOG TPR repeat
LOPFHFCG_02378 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LOPFHFCG_02379 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LOPFHFCG_02380 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LOPFHFCG_02381 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LOPFHFCG_02382 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LOPFHFCG_02383 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
LOPFHFCG_02384 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LOPFHFCG_02385 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LOPFHFCG_02386 3.4e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LOPFHFCG_02387 4.6e-64 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LOPFHFCG_02388 1.7e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LOPFHFCG_02389 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LOPFHFCG_02390 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
LOPFHFCG_02391 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LOPFHFCG_02392 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LOPFHFCG_02393 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LOPFHFCG_02394 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LOPFHFCG_02395 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LOPFHFCG_02396 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
LOPFHFCG_02397 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LOPFHFCG_02398 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LOPFHFCG_02399 5.4e-138 yphF
LOPFHFCG_02400 1.6e-18 yphE S Protein of unknown function (DUF2768)
LOPFHFCG_02401 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LOPFHFCG_02402 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LOPFHFCG_02403 1.6e-28 ypzH
LOPFHFCG_02404 2.5e-161 seaA S YIEGIA protein
LOPFHFCG_02405 1.3e-102 yphA
LOPFHFCG_02406 1e-07 S YpzI-like protein
LOPFHFCG_02407 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LOPFHFCG_02408 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
LOPFHFCG_02409 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LOPFHFCG_02410 1.8e-23 S Family of unknown function (DUF5359)
LOPFHFCG_02411 9.2e-113 ypfA M Flagellar protein YcgR
LOPFHFCG_02412 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
LOPFHFCG_02413 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
LOPFHFCG_02414 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
LOPFHFCG_02415 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
LOPFHFCG_02416 7.3e-247 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LOPFHFCG_02417 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LOPFHFCG_02418 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
LOPFHFCG_02419 2.8e-81 ypbF S Protein of unknown function (DUF2663)
LOPFHFCG_02420 4.6e-81 ypbE M Lysin motif
LOPFHFCG_02421 2.2e-100 ypbD S metal-dependent membrane protease
LOPFHFCG_02422 3.2e-286 recQ 3.6.4.12 L DNA helicase
LOPFHFCG_02423 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
LOPFHFCG_02424 4.7e-41 fer C Ferredoxin
LOPFHFCG_02425 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LOPFHFCG_02426 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOPFHFCG_02427 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LOPFHFCG_02428 6.8e-201 rsiX
LOPFHFCG_02429 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_02430 0.0 resE 2.7.13.3 T Histidine kinase
LOPFHFCG_02431 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_02432 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LOPFHFCG_02433 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
LOPFHFCG_02434 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LOPFHFCG_02435 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LOPFHFCG_02436 1.9e-87 spmB S Spore maturation protein
LOPFHFCG_02437 3.5e-103 spmA S Spore maturation protein
LOPFHFCG_02438 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
LOPFHFCG_02439 4e-98 ypuI S Protein of unknown function (DUF3907)
LOPFHFCG_02440 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LOPFHFCG_02441 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LOPFHFCG_02442 4.5e-94 ypuF S Domain of unknown function (DUF309)
LOPFHFCG_02443 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOPFHFCG_02444 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LOPFHFCG_02445 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LOPFHFCG_02446 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
LOPFHFCG_02447 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LOPFHFCG_02448 6e-55 ypuD
LOPFHFCG_02449 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LOPFHFCG_02450 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
LOPFHFCG_02451 1.5e-17 S SNARE associated Golgi protein
LOPFHFCG_02454 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LOPFHFCG_02455 1.3e-149 ypuA S Secreted protein
LOPFHFCG_02456 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LOPFHFCG_02457 1.4e-273 spoVAF EG Stage V sporulation protein AF
LOPFHFCG_02458 1.4e-110 spoVAEA S stage V sporulation protein
LOPFHFCG_02459 2.2e-57 spoVAEB S stage V sporulation protein
LOPFHFCG_02460 9e-192 spoVAD I Stage V sporulation protein AD
LOPFHFCG_02461 2.3e-78 spoVAC S stage V sporulation protein AC
LOPFHFCG_02462 1e-67 spoVAB S Stage V sporulation protein AB
LOPFHFCG_02463 7.4e-112 spoVAA S Stage V sporulation protein AA
LOPFHFCG_02464 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOPFHFCG_02465 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LOPFHFCG_02466 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
LOPFHFCG_02467 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
LOPFHFCG_02468 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LOPFHFCG_02469 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LOPFHFCG_02470 2.6e-166 xerD L recombinase XerD
LOPFHFCG_02471 3.7e-37 S Protein of unknown function (DUF4227)
LOPFHFCG_02472 2.4e-80 fur P Belongs to the Fur family
LOPFHFCG_02473 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LOPFHFCG_02474 2e-32 yqkK
LOPFHFCG_02475 5.5e-242 mleA 1.1.1.38 C malic enzyme
LOPFHFCG_02476 3.1e-235 mleN C Na H antiporter
LOPFHFCG_02477 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
LOPFHFCG_02478 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
LOPFHFCG_02479 4.5e-58 ansR K Transcriptional regulator
LOPFHFCG_02480 3e-223 yqxK 3.6.4.12 L DNA helicase
LOPFHFCG_02481 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LOPFHFCG_02483 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
LOPFHFCG_02484 4e-14 yqkE S Protein of unknown function (DUF3886)
LOPFHFCG_02485 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
LOPFHFCG_02486 9.4e-39 yqkC S Protein of unknown function (DUF2552)
LOPFHFCG_02487 2.8e-54 yqkB S Belongs to the HesB IscA family
LOPFHFCG_02488 4.7e-196 yqkA K GrpB protein
LOPFHFCG_02489 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
LOPFHFCG_02490 3.6e-87 yqjY K acetyltransferase
LOPFHFCG_02491 2.2e-49 S YolD-like protein
LOPFHFCG_02492 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOPFHFCG_02494 5.2e-226 yqjV G Major Facilitator Superfamily
LOPFHFCG_02496 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOPFHFCG_02497 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
LOPFHFCG_02498 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LOPFHFCG_02499 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_02500 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
LOPFHFCG_02501 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOPFHFCG_02502 0.0 rocB E arginine degradation protein
LOPFHFCG_02503 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LOPFHFCG_02504 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LOPFHFCG_02505 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LOPFHFCG_02506 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LOPFHFCG_02507 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LOPFHFCG_02508 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LOPFHFCG_02509 4.5e-24 yqzJ
LOPFHFCG_02510 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LOPFHFCG_02511 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
LOPFHFCG_02512 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
LOPFHFCG_02513 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LOPFHFCG_02514 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
LOPFHFCG_02516 1.4e-98 yqjB S protein conserved in bacteria
LOPFHFCG_02517 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
LOPFHFCG_02518 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LOPFHFCG_02519 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
LOPFHFCG_02520 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
LOPFHFCG_02521 9.3e-77 yqiW S Belongs to the UPF0403 family
LOPFHFCG_02522 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LOPFHFCG_02523 7.9e-208 norA EGP Major facilitator Superfamily
LOPFHFCG_02524 2.6e-152 bmrR K helix_turn_helix, mercury resistance
LOPFHFCG_02525 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LOPFHFCG_02526 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LOPFHFCG_02527 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LOPFHFCG_02528 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LOPFHFCG_02529 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
LOPFHFCG_02530 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
LOPFHFCG_02531 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
LOPFHFCG_02532 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
LOPFHFCG_02533 4e-34 yqzF S Protein of unknown function (DUF2627)
LOPFHFCG_02534 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LOPFHFCG_02535 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
LOPFHFCG_02536 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
LOPFHFCG_02537 1.8e-212 mmgC I acyl-CoA dehydrogenase
LOPFHFCG_02538 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
LOPFHFCG_02539 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
LOPFHFCG_02540 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LOPFHFCG_02541 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
LOPFHFCG_02542 5.9e-27
LOPFHFCG_02543 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LOPFHFCG_02545 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LOPFHFCG_02546 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
LOPFHFCG_02547 0.0 recN L May be involved in recombinational repair of damaged DNA
LOPFHFCG_02548 1.7e-78 argR K Regulates arginine biosynthesis genes
LOPFHFCG_02549 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
LOPFHFCG_02550 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LOPFHFCG_02551 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LOPFHFCG_02552 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LOPFHFCG_02553 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LOPFHFCG_02554 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LOPFHFCG_02555 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LOPFHFCG_02556 2.1e-67 yqhY S protein conserved in bacteria
LOPFHFCG_02557 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LOPFHFCG_02558 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LOPFHFCG_02559 9.9e-91 spoIIIAH S SpoIIIAH-like protein
LOPFHFCG_02560 6.9e-103 spoIIIAG S stage III sporulation protein AG
LOPFHFCG_02561 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
LOPFHFCG_02562 1.3e-197 spoIIIAE S stage III sporulation protein AE
LOPFHFCG_02563 2.3e-58 spoIIIAD S Stage III sporulation protein AD
LOPFHFCG_02564 7.6e-29 spoIIIAC S stage III sporulation protein AC
LOPFHFCG_02565 2.9e-85 spoIIIAB S Stage III sporulation protein
LOPFHFCG_02566 1.2e-171 spoIIIAA S stage III sporulation protein AA
LOPFHFCG_02567 7.9e-37 yqhV S Protein of unknown function (DUF2619)
LOPFHFCG_02568 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LOPFHFCG_02569 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LOPFHFCG_02570 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
LOPFHFCG_02571 2.3e-93 yqhR S Conserved membrane protein YqhR
LOPFHFCG_02572 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
LOPFHFCG_02573 2.2e-61 yqhP
LOPFHFCG_02574 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
LOPFHFCG_02575 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LOPFHFCG_02576 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LOPFHFCG_02577 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
LOPFHFCG_02578 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LOPFHFCG_02579 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LOPFHFCG_02580 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LOPFHFCG_02581 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LOPFHFCG_02582 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
LOPFHFCG_02583 1.2e-24 sinI S Anti-repressor SinI
LOPFHFCG_02584 1e-54 sinR K transcriptional
LOPFHFCG_02585 2.3e-142 tasA S Cell division protein FtsN
LOPFHFCG_02586 6.7e-59 sipW 3.4.21.89 U Signal peptidase
LOPFHFCG_02587 2.1e-116 yqxM
LOPFHFCG_02588 7.3e-54 yqzG S Protein of unknown function (DUF3889)
LOPFHFCG_02589 1.4e-26 yqzE S YqzE-like protein
LOPFHFCG_02590 3.7e-42 S ComG operon protein 7
LOPFHFCG_02591 5.5e-49 comGF U Putative Competence protein ComGF
LOPFHFCG_02592 1.1e-59 comGE
LOPFHFCG_02593 4.4e-71 gspH NU protein transport across the cell outer membrane
LOPFHFCG_02594 1.4e-47 comGC U Required for transformation and DNA binding
LOPFHFCG_02595 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
LOPFHFCG_02596 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LOPFHFCG_02598 7.2e-175 corA P Mg2 transporter protein
LOPFHFCG_02599 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LOPFHFCG_02600 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LOPFHFCG_02602 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
LOPFHFCG_02603 1.8e-37 yqgY S Protein of unknown function (DUF2626)
LOPFHFCG_02604 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LOPFHFCG_02605 8.9e-23 yqgW S Protein of unknown function (DUF2759)
LOPFHFCG_02606 6.9e-50 yqgV S Thiamine-binding protein
LOPFHFCG_02607 2.7e-199 yqgU
LOPFHFCG_02608 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
LOPFHFCG_02609 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOPFHFCG_02610 5.2e-181 glcK 2.7.1.2 G Glucokinase
LOPFHFCG_02611 3.1e-33 yqgQ S Protein conserved in bacteria
LOPFHFCG_02612 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LOPFHFCG_02613 2.5e-09 yqgO
LOPFHFCG_02614 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LOPFHFCG_02615 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LOPFHFCG_02616 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
LOPFHFCG_02618 9.2e-51 yqzD
LOPFHFCG_02619 1.9e-75 yqzC S YceG-like family
LOPFHFCG_02620 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LOPFHFCG_02621 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LOPFHFCG_02622 4.4e-158 pstA P Phosphate transport system permease
LOPFHFCG_02623 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
LOPFHFCG_02624 5.3e-151 pstS P Phosphate
LOPFHFCG_02625 0.0 pbpA 3.4.16.4 M penicillin-binding protein
LOPFHFCG_02626 2.5e-231 yqgE EGP Major facilitator superfamily
LOPFHFCG_02627 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
LOPFHFCG_02628 4e-73 yqgC S protein conserved in bacteria
LOPFHFCG_02629 8.5e-134 yqgB S Protein of unknown function (DUF1189)
LOPFHFCG_02630 2.2e-75 yqgA
LOPFHFCG_02631 5.2e-47 yqfZ M LysM domain
LOPFHFCG_02632 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LOPFHFCG_02633 4.3e-62 yqfX S membrane
LOPFHFCG_02634 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
LOPFHFCG_02635 1.9e-77 zur P Belongs to the Fur family
LOPFHFCG_02636 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LOPFHFCG_02637 2.1e-36 yqfT S Protein of unknown function (DUF2624)
LOPFHFCG_02638 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LOPFHFCG_02639 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LOPFHFCG_02640 2.9e-14 yqfQ S YqfQ-like protein
LOPFHFCG_02641 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LOPFHFCG_02642 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LOPFHFCG_02643 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
LOPFHFCG_02644 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
LOPFHFCG_02645 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LOPFHFCG_02646 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LOPFHFCG_02647 4.5e-88 yaiI S Belongs to the UPF0178 family
LOPFHFCG_02648 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LOPFHFCG_02649 4.5e-112 ccpN K CBS domain
LOPFHFCG_02650 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LOPFHFCG_02651 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LOPFHFCG_02652 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
LOPFHFCG_02653 8.4e-19 S YqzL-like protein
LOPFHFCG_02654 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LOPFHFCG_02655 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LOPFHFCG_02656 7.9e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LOPFHFCG_02657 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LOPFHFCG_02658 0.0 yqfF S membrane-associated HD superfamily hydrolase
LOPFHFCG_02660 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
LOPFHFCG_02661 5.6e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
LOPFHFCG_02662 2.7e-45 yqfC S sporulation protein YqfC
LOPFHFCG_02663 1.3e-19 yqfB
LOPFHFCG_02664 4.3e-122 yqfA S UPF0365 protein
LOPFHFCG_02665 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LOPFHFCG_02666 2.5e-61 yqeY S Yqey-like protein
LOPFHFCG_02667 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LOPFHFCG_02668 1.6e-158 yqeW P COG1283 Na phosphate symporter
LOPFHFCG_02669 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
LOPFHFCG_02670 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LOPFHFCG_02671 5.4e-175 prmA J Methylates ribosomal protein L11
LOPFHFCG_02672 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LOPFHFCG_02673 0.0 dnaK O Heat shock 70 kDa protein
LOPFHFCG_02674 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LOPFHFCG_02675 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LOPFHFCG_02676 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
LOPFHFCG_02677 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LOPFHFCG_02678 1e-54 yqxA S Protein of unknown function (DUF3679)
LOPFHFCG_02679 6.9e-223 spoIIP M stage II sporulation protein P
LOPFHFCG_02680 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LOPFHFCG_02681 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
LOPFHFCG_02682 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
LOPFHFCG_02683 4.1e-15 S YqzM-like protein
LOPFHFCG_02684 0.0 comEC S Competence protein ComEC
LOPFHFCG_02685 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
LOPFHFCG_02686 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
LOPFHFCG_02687 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LOPFHFCG_02688 2.9e-139 yqeM Q Methyltransferase
LOPFHFCG_02689 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LOPFHFCG_02690 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LOPFHFCG_02691 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LOPFHFCG_02692 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
LOPFHFCG_02693 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LOPFHFCG_02694 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LOPFHFCG_02695 5.3e-95 yqeG S hydrolase of the HAD superfamily
LOPFHFCG_02697 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
LOPFHFCG_02698 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOPFHFCG_02699 4.7e-106 yqeD S SNARE associated Golgi protein
LOPFHFCG_02700 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
LOPFHFCG_02701 2.3e-133 yqeB
LOPFHFCG_02702 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
LOPFHFCG_02703 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOPFHFCG_02704 1.4e-281 cisA2 L Recombinase
LOPFHFCG_02705 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
LOPFHFCG_02706 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
LOPFHFCG_02707 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOPFHFCG_02708 1.6e-54 arsR K ArsR family transcriptional regulator
LOPFHFCG_02709 1.1e-152 yqcI S YqcI/YcgG family
LOPFHFCG_02710 1.6e-96 S Tetratricopeptide repeat
LOPFHFCG_02713 3.8e-277 A Pre-toxin TG
LOPFHFCG_02714 1.1e-104 S Suppressor of fused protein (SUFU)
LOPFHFCG_02716 5e-60
LOPFHFCG_02718 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LOPFHFCG_02719 2.6e-68 S Bacteriophage holin family
LOPFHFCG_02720 4.8e-165 xepA
LOPFHFCG_02721 1.3e-23
LOPFHFCG_02722 4.1e-56 xkdW S XkdW protein
LOPFHFCG_02723 2e-221
LOPFHFCG_02724 9.6e-40
LOPFHFCG_02725 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LOPFHFCG_02726 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LOPFHFCG_02727 9.6e-71 xkdS S Protein of unknown function (DUF2634)
LOPFHFCG_02728 1.8e-38 xkdR S Protein of unknown function (DUF2577)
LOPFHFCG_02729 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
LOPFHFCG_02730 9e-114 xkdP S Lysin motif
LOPFHFCG_02731 0.0 xkdO L Transglycosylase SLT domain
LOPFHFCG_02732 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
LOPFHFCG_02734 3.6e-76 xkdM S Phage tail tube protein
LOPFHFCG_02735 5.5e-256 xkdK S Phage tail sheath C-terminal domain
LOPFHFCG_02736 3.2e-26
LOPFHFCG_02737 1.4e-77
LOPFHFCG_02738 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
LOPFHFCG_02739 6.7e-65 yqbH S Domain of unknown function (DUF3599)
LOPFHFCG_02740 2.1e-67 S Protein of unknown function (DUF3199)
LOPFHFCG_02741 3.6e-51 S YqbF, hypothetical protein domain
LOPFHFCG_02742 1.9e-167 xkdG S Phage capsid family
LOPFHFCG_02743 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
LOPFHFCG_02744 2e-115
LOPFHFCG_02745 5.7e-169 S Phage Mu protein F like protein
LOPFHFCG_02746 5.9e-296 yqbA S portal protein
LOPFHFCG_02747 2.4e-253 S phage terminase, large subunit
LOPFHFCG_02748 6.3e-107 yqaS L DNA packaging
LOPFHFCG_02750 6.5e-81 L Transposase
LOPFHFCG_02751 1.6e-166
LOPFHFCG_02752 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
LOPFHFCG_02753 7.2e-74 rusA L Endodeoxyribonuclease RusA
LOPFHFCG_02755 5.9e-168 xkdC L IstB-like ATP binding protein
LOPFHFCG_02756 4.7e-123 3.1.3.16 L DnaD domain protein
LOPFHFCG_02757 2.5e-155 recT L RecT family
LOPFHFCG_02758 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
LOPFHFCG_02762 1.2e-103
LOPFHFCG_02764 6.5e-37 K Helix-turn-helix XRE-family like proteins
LOPFHFCG_02765 1.1e-56 K sequence-specific DNA binding
LOPFHFCG_02767 1e-101 adk 2.7.4.3 F adenylate kinase activity
LOPFHFCG_02768 1.4e-100 yqaB E IrrE N-terminal-like domain
LOPFHFCG_02769 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LOPFHFCG_02770 2e-68 psiE S Protein PsiE homolog
LOPFHFCG_02771 9e-237 yrkQ T Histidine kinase
LOPFHFCG_02772 1.1e-127 T Transcriptional regulator
LOPFHFCG_02773 8.2e-224 yrkO P Protein of unknown function (DUF418)
LOPFHFCG_02774 6e-105 yrkN K Acetyltransferase (GNAT) family
LOPFHFCG_02775 1.5e-97 ywrO S Flavodoxin-like fold
LOPFHFCG_02776 2.8e-79 S Protein of unknown function with HXXEE motif
LOPFHFCG_02777 4.3e-117 yrkJ S membrane transporter protein
LOPFHFCG_02778 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
LOPFHFCG_02779 1.1e-219 yrkH P Rhodanese Homology Domain
LOPFHFCG_02780 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
LOPFHFCG_02781 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
LOPFHFCG_02782 7.8e-39 yrkD S protein conserved in bacteria
LOPFHFCG_02783 2.6e-108 yrkC G Cupin domain
LOPFHFCG_02784 4.8e-151 bltR K helix_turn_helix, mercury resistance
LOPFHFCG_02785 3.5e-211 blt EGP Major facilitator Superfamily
LOPFHFCG_02786 1.4e-83 bltD 2.3.1.57 K FR47-like protein
LOPFHFCG_02787 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LOPFHFCG_02788 2.1e-17 S YrzO-like protein
LOPFHFCG_02789 1.7e-171 yrdR EG EamA-like transporter family
LOPFHFCG_02790 5.9e-160 yrdQ K Transcriptional regulator
LOPFHFCG_02791 2e-199 trkA P Oxidoreductase
LOPFHFCG_02792 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
LOPFHFCG_02793 1.3e-66 yodA S tautomerase
LOPFHFCG_02794 7.7e-163 gltR K LysR substrate binding domain
LOPFHFCG_02796 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
LOPFHFCG_02797 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
LOPFHFCG_02798 3.3e-138 azlC E AzlC protein
LOPFHFCG_02799 2.2e-79 bkdR K helix_turn_helix ASNC type
LOPFHFCG_02800 4.1e-46 yrdF K ribonuclease inhibitor
LOPFHFCG_02801 4.1e-231 cypA C Cytochrome P450
LOPFHFCG_02802 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
LOPFHFCG_02803 1.9e-57 S Protein of unknown function (DUF2568)
LOPFHFCG_02804 1.2e-91 yrdA S DinB family
LOPFHFCG_02805 7.6e-168 aadK G Streptomycin adenylyltransferase
LOPFHFCG_02806 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LOPFHFCG_02807 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LOPFHFCG_02808 3e-125 yrpD S Domain of unknown function, YrpD
LOPFHFCG_02810 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
LOPFHFCG_02811 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_02812 4.5e-188 yrpG C Aldo/keto reductase family
LOPFHFCG_02813 9.5e-226 yraO C Citrate transporter
LOPFHFCG_02814 1.2e-163 yraN K Transcriptional regulator
LOPFHFCG_02815 2.4e-206 yraM S PrpF protein
LOPFHFCG_02817 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LOPFHFCG_02818 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOPFHFCG_02819 3.2e-155 S Alpha beta hydrolase
LOPFHFCG_02820 1.7e-60 T sh3 domain protein
LOPFHFCG_02821 2.4e-61 T sh3 domain protein
LOPFHFCG_02822 1.3e-66 E Glyoxalase-like domain
LOPFHFCG_02823 5.3e-37 yraG
LOPFHFCG_02824 6.4e-63 yraF M Spore coat protein
LOPFHFCG_02825 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LOPFHFCG_02826 2.6e-26 yraE
LOPFHFCG_02827 1.1e-49 yraD M Spore coat protein
LOPFHFCG_02828 4.3e-47 yraB K helix_turn_helix, mercury resistance
LOPFHFCG_02829 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
LOPFHFCG_02830 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
LOPFHFCG_02831 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
LOPFHFCG_02832 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
LOPFHFCG_02833 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
LOPFHFCG_02834 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
LOPFHFCG_02835 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
LOPFHFCG_02836 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
LOPFHFCG_02837 0.0 levR K PTS system fructose IIA component
LOPFHFCG_02838 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_02839 3.6e-106 yrhP E LysE type translocator
LOPFHFCG_02840 1.8e-150 yrhO K Archaeal transcriptional regulator TrmB
LOPFHFCG_02841 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_02842 1.9e-150 rsiV S Protein of unknown function (DUF3298)
LOPFHFCG_02843 0.0 yrhL I Acyltransferase family
LOPFHFCG_02844 1.5e-46 yrhK S YrhK-like protein
LOPFHFCG_02845 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LOPFHFCG_02846 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
LOPFHFCG_02847 4.5e-97 yrhH Q methyltransferase
LOPFHFCG_02850 1.8e-142 focA P Formate nitrite
LOPFHFCG_02851 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
LOPFHFCG_02852 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
LOPFHFCG_02853 1.4e-78 yrhD S Protein of unknown function (DUF1641)
LOPFHFCG_02854 4.6e-35 yrhC S YrhC-like protein
LOPFHFCG_02855 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LOPFHFCG_02856 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
LOPFHFCG_02857 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LOPFHFCG_02858 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
LOPFHFCG_02859 7e-27 yrzA S Protein of unknown function (DUF2536)
LOPFHFCG_02860 4.2e-63 yrrS S Protein of unknown function (DUF1510)
LOPFHFCG_02861 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
LOPFHFCG_02862 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LOPFHFCG_02863 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
LOPFHFCG_02864 2.7e-246 yegQ O COG0826 Collagenase and related proteases
LOPFHFCG_02865 7.8e-174 yegQ O Peptidase U32
LOPFHFCG_02866 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
LOPFHFCG_02867 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LOPFHFCG_02868 1.2e-45 yrzB S Belongs to the UPF0473 family
LOPFHFCG_02869 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LOPFHFCG_02870 1.7e-41 yrzL S Belongs to the UPF0297 family
LOPFHFCG_02871 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LOPFHFCG_02872 7.8e-170 yrrI S AI-2E family transporter
LOPFHFCG_02873 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LOPFHFCG_02874 7.7e-141 glnH ET Belongs to the bacterial solute-binding protein 3 family
LOPFHFCG_02875 2.6e-107 gluC P ABC transporter
LOPFHFCG_02876 7.6e-107 glnP P ABC transporter
LOPFHFCG_02877 8e-08 S Protein of unknown function (DUF3918)
LOPFHFCG_02878 9.8e-31 yrzR
LOPFHFCG_02879 5e-81 yrrD S protein conserved in bacteria
LOPFHFCG_02880 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LOPFHFCG_02881 1.4e-15 S COG0457 FOG TPR repeat
LOPFHFCG_02882 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LOPFHFCG_02883 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
LOPFHFCG_02884 1.2e-70 cymR K Transcriptional regulator
LOPFHFCG_02885 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LOPFHFCG_02886 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LOPFHFCG_02887 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LOPFHFCG_02888 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
LOPFHFCG_02890 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
LOPFHFCG_02891 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LOPFHFCG_02892 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LOPFHFCG_02893 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LOPFHFCG_02894 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LOPFHFCG_02895 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
LOPFHFCG_02896 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
LOPFHFCG_02897 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LOPFHFCG_02898 9.4e-49 yrzD S Post-transcriptional regulator
LOPFHFCG_02899 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOPFHFCG_02900 2.2e-114 yrbG S membrane
LOPFHFCG_02901 1.2e-74 yrzE S Protein of unknown function (DUF3792)
LOPFHFCG_02902 1.1e-38 yajC U Preprotein translocase subunit YajC
LOPFHFCG_02903 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LOPFHFCG_02904 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LOPFHFCG_02905 2.6e-18 yrzS S Protein of unknown function (DUF2905)
LOPFHFCG_02906 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LOPFHFCG_02907 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LOPFHFCG_02908 4.8e-93 bofC S BofC C-terminal domain
LOPFHFCG_02909 5.3e-253 csbX EGP Major facilitator Superfamily
LOPFHFCG_02910 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
LOPFHFCG_02911 6.5e-119 yrzF T serine threonine protein kinase
LOPFHFCG_02913 2.6e-35 S Family of unknown function (DUF5412)
LOPFHFCG_02914 1.8e-262 alsT E Sodium alanine symporter
LOPFHFCG_02915 1.9e-127 yebC K transcriptional regulatory protein
LOPFHFCG_02916 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LOPFHFCG_02917 3.1e-156 safA M spore coat assembly protein SafA
LOPFHFCG_02918 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LOPFHFCG_02919 8.1e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
LOPFHFCG_02920 2e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LOPFHFCG_02921 9.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
LOPFHFCG_02922 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
LOPFHFCG_02923 3.3e-163 pheA 4.2.1.51 E Prephenate dehydratase
LOPFHFCG_02924 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
LOPFHFCG_02925 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LOPFHFCG_02926 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
LOPFHFCG_02927 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LOPFHFCG_02928 4.1e-56 ysxB J ribosomal protein
LOPFHFCG_02929 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LOPFHFCG_02930 2e-160 spoIVFB S Stage IV sporulation protein
LOPFHFCG_02931 1.4e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
LOPFHFCG_02932 3.3e-144 minD D Belongs to the ParA family
LOPFHFCG_02933 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LOPFHFCG_02934 1.4e-84 mreD M shape-determining protein
LOPFHFCG_02935 1.1e-156 mreC M Involved in formation and maintenance of cell shape
LOPFHFCG_02936 1.8e-184 mreB D Rod shape-determining protein MreB
LOPFHFCG_02937 1.3e-125 radC E Belongs to the UPF0758 family
LOPFHFCG_02938 2.4e-101 maf D septum formation protein Maf
LOPFHFCG_02939 6e-164 spoIIB S Sporulation related domain
LOPFHFCG_02940 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LOPFHFCG_02941 2.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LOPFHFCG_02942 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LOPFHFCG_02943 1.6e-25
LOPFHFCG_02944 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LOPFHFCG_02945 3.3e-186 spoVID M stage VI sporulation protein D
LOPFHFCG_02946 9.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LOPFHFCG_02947 1.1e-181 hemB 4.2.1.24 H Belongs to the ALAD family
LOPFHFCG_02948 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LOPFHFCG_02949 5.7e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LOPFHFCG_02950 3.6e-146 hemX O cytochrome C
LOPFHFCG_02951 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LOPFHFCG_02952 5.4e-89 ysxD
LOPFHFCG_02953 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
LOPFHFCG_02954 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LOPFHFCG_02955 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
LOPFHFCG_02956 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LOPFHFCG_02957 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LOPFHFCG_02958 2.3e-187 ysoA H Tetratricopeptide repeat
LOPFHFCG_02959 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LOPFHFCG_02960 9.1e-46 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LOPFHFCG_02961 1.2e-242 tetL EGP Major Facilitator Superfamily
LOPFHFCG_02962 1.8e-220 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LOPFHFCG_02963 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LOPFHFCG_02964 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LOPFHFCG_02965 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LOPFHFCG_02966 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
LOPFHFCG_02967 0.0 ilvB 2.2.1.6 E Acetolactate synthase
LOPFHFCG_02969 3.6e-64 ysnE K acetyltransferase
LOPFHFCG_02970 1.6e-130 ysnF S protein conserved in bacteria
LOPFHFCG_02972 1.4e-92 ysnB S Phosphoesterase
LOPFHFCG_02973 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LOPFHFCG_02974 1.2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LOPFHFCG_02975 2.9e-196 gerM S COG5401 Spore germination protein
LOPFHFCG_02976 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LOPFHFCG_02977 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
LOPFHFCG_02978 3.3e-30 gerE K Transcriptional regulator
LOPFHFCG_02979 9.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
LOPFHFCG_02980 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LOPFHFCG_02981 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LOPFHFCG_02982 2.4e-107 sdhC C succinate dehydrogenase
LOPFHFCG_02983 1.2e-79 yslB S Protein of unknown function (DUF2507)
LOPFHFCG_02984 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LOPFHFCG_02985 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LOPFHFCG_02986 2e-52 trxA O Belongs to the thioredoxin family
LOPFHFCG_02987 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
LOPFHFCG_02989 7.9e-177 etfA C Electron transfer flavoprotein
LOPFHFCG_02990 4.5e-135 etfB C Electron transfer flavoprotein
LOPFHFCG_02991 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LOPFHFCG_02992 4e-99 fadR K Transcriptional regulator
LOPFHFCG_02993 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LOPFHFCG_02994 7.3e-68 yshE S membrane
LOPFHFCG_02995 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LOPFHFCG_02996 0.0 polX L COG1796 DNA polymerase IV (family X)
LOPFHFCG_02997 3.9e-85 cvpA S membrane protein, required for colicin V production
LOPFHFCG_02998 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LOPFHFCG_02999 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LOPFHFCG_03000 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LOPFHFCG_03001 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LOPFHFCG_03002 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LOPFHFCG_03003 2.6e-32 sspI S Belongs to the SspI family
LOPFHFCG_03004 3.7e-207 ysfB KT regulator
LOPFHFCG_03005 1.6e-258 glcD 1.1.3.15 C Glycolate oxidase subunit
LOPFHFCG_03006 3.5e-252 glcF C Glycolate oxidase
LOPFHFCG_03007 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
LOPFHFCG_03009 0.0 cstA T Carbon starvation protein
LOPFHFCG_03010 1.1e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
LOPFHFCG_03011 3.8e-143 araQ G transport system permease
LOPFHFCG_03012 4.2e-167 araP G carbohydrate transport
LOPFHFCG_03013 2.9e-251 araN G carbohydrate transport
LOPFHFCG_03014 3.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LOPFHFCG_03015 8.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LOPFHFCG_03016 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LOPFHFCG_03017 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
LOPFHFCG_03018 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LOPFHFCG_03019 1.2e-99 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LOPFHFCG_03020 7.9e-57 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LOPFHFCG_03021 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
LOPFHFCG_03022 9.2e-68 ysdB S Sigma-w pathway protein YsdB
LOPFHFCG_03023 1.7e-44 ysdA S Membrane
LOPFHFCG_03024 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LOPFHFCG_03025 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LOPFHFCG_03026 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LOPFHFCG_03028 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LOPFHFCG_03029 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LOPFHFCG_03030 7.8e-129 lytT T COG3279 Response regulator of the LytR AlgR family
LOPFHFCG_03031 0.0 lytS 2.7.13.3 T Histidine kinase
LOPFHFCG_03032 1.1e-147 ysaA S HAD-hyrolase-like
LOPFHFCG_03033 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LOPFHFCG_03035 1.1e-155 ytxC S YtxC-like family
LOPFHFCG_03036 4.9e-111 ytxB S SNARE associated Golgi protein
LOPFHFCG_03037 6.6e-173 dnaI L Primosomal protein DnaI
LOPFHFCG_03038 2.9e-265 dnaB L Membrane attachment protein
LOPFHFCG_03039 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LOPFHFCG_03040 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LOPFHFCG_03041 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LOPFHFCG_03042 8.4e-66 ytcD K Transcriptional regulator
LOPFHFCG_03043 4.9e-205 ytbD EGP Major facilitator Superfamily
LOPFHFCG_03044 8.9e-161 ytbE S reductase
LOPFHFCG_03045 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LOPFHFCG_03046 1.1e-107 ytaF P Probably functions as a manganese efflux pump
LOPFHFCG_03047 2.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LOPFHFCG_03048 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LOPFHFCG_03049 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
LOPFHFCG_03050 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_03051 1.2e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LOPFHFCG_03052 4.1e-242 icd 1.1.1.42 C isocitrate
LOPFHFCG_03053 1.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
LOPFHFCG_03054 5.2e-70 yeaL S membrane
LOPFHFCG_03055 2.6e-192 ytvI S sporulation integral membrane protein YtvI
LOPFHFCG_03056 4.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
LOPFHFCG_03057 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LOPFHFCG_03058 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LOPFHFCG_03059 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LOPFHFCG_03060 9.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LOPFHFCG_03061 2e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
LOPFHFCG_03062 0.0 dnaE 2.7.7.7 L DNA polymerase
LOPFHFCG_03063 3.2e-56 ytrH S Sporulation protein YtrH
LOPFHFCG_03064 8.2e-69 ytrI
LOPFHFCG_03065 9.2e-29
LOPFHFCG_03066 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
LOPFHFCG_03067 2.4e-47 ytpI S YtpI-like protein
LOPFHFCG_03068 8e-241 ytoI K transcriptional regulator containing CBS domains
LOPFHFCG_03069 1.2e-158 ytnM S membrane transporter protein
LOPFHFCG_03070 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
LOPFHFCG_03071 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
LOPFHFCG_03072 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_03073 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
LOPFHFCG_03074 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_03075 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LOPFHFCG_03076 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
LOPFHFCG_03077 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
LOPFHFCG_03078 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
LOPFHFCG_03079 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
LOPFHFCG_03080 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
LOPFHFCG_03081 2.9e-173 ytlI K LysR substrate binding domain
LOPFHFCG_03082 1.7e-130 ytkL S Belongs to the UPF0173 family
LOPFHFCG_03083 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_03085 3.4e-266 argH 4.3.2.1 E argininosuccinate lyase
LOPFHFCG_03086 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LOPFHFCG_03087 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LOPFHFCG_03088 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LOPFHFCG_03089 5.4e-165 ytxK 2.1.1.72 L DNA methylase
LOPFHFCG_03090 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LOPFHFCG_03091 8.7e-70 ytfJ S Sporulation protein YtfJ
LOPFHFCG_03092 5.6e-116 ytfI S Protein of unknown function (DUF2953)
LOPFHFCG_03093 2.5e-86 yteJ S RDD family
LOPFHFCG_03094 1.3e-177 sppA OU signal peptide peptidase SppA
LOPFHFCG_03095 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LOPFHFCG_03096 0.0 ytcJ S amidohydrolase
LOPFHFCG_03097 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LOPFHFCG_03098 2e-29 sspB S spore protein
LOPFHFCG_03099 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LOPFHFCG_03100 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
LOPFHFCG_03101 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
LOPFHFCG_03102 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LOPFHFCG_03103 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LOPFHFCG_03104 3.4e-109 yttP K Transcriptional regulator
LOPFHFCG_03105 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LOPFHFCG_03106 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
LOPFHFCG_03107 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LOPFHFCG_03109 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LOPFHFCG_03110 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LOPFHFCG_03111 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LOPFHFCG_03112 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
LOPFHFCG_03113 1.9e-225 acuC BQ histone deacetylase
LOPFHFCG_03114 1.4e-125 motS N Flagellar motor protein
LOPFHFCG_03115 7.1e-147 motA N flagellar motor
LOPFHFCG_03116 1.7e-182 ccpA K catabolite control protein A
LOPFHFCG_03117 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LOPFHFCG_03118 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
LOPFHFCG_03119 6.6e-17 ytxH S COG4980 Gas vesicle protein
LOPFHFCG_03120 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LOPFHFCG_03121 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LOPFHFCG_03122 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LOPFHFCG_03123 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LOPFHFCG_03124 9.8e-149 ytpQ S Belongs to the UPF0354 family
LOPFHFCG_03125 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LOPFHFCG_03126 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
LOPFHFCG_03127 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LOPFHFCG_03128 9.8e-52 ytzB S small secreted protein
LOPFHFCG_03129 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
LOPFHFCG_03130 4.2e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
LOPFHFCG_03131 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LOPFHFCG_03132 2e-45 ytzH S YtzH-like protein
LOPFHFCG_03133 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
LOPFHFCG_03134 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
LOPFHFCG_03135 8.6e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LOPFHFCG_03136 1.3e-165 ytlQ
LOPFHFCG_03137 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LOPFHFCG_03138 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LOPFHFCG_03139 7.1e-272 pepV 3.5.1.18 E Dipeptidase
LOPFHFCG_03140 7.2e-226 pbuO S permease
LOPFHFCG_03141 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
LOPFHFCG_03142 4.3e-132 ythP V ABC transporter
LOPFHFCG_03143 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
LOPFHFCG_03144 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LOPFHFCG_03145 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOPFHFCG_03146 8.2e-232 ytfP S HI0933-like protein
LOPFHFCG_03147 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LOPFHFCG_03148 3.1e-26 yteV S Sporulation protein Cse60
LOPFHFCG_03149 4.8e-117 yteU S Integral membrane protein
LOPFHFCG_03150 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
LOPFHFCG_03151 4.6e-73 yteS G transport
LOPFHFCG_03152 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
LOPFHFCG_03153 2.2e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
LOPFHFCG_03154 1.4e-163 ytdP K Transcriptional regulator
LOPFHFCG_03155 3.7e-221 ytdP K Transcriptional regulator
LOPFHFCG_03156 2.4e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
LOPFHFCG_03157 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
LOPFHFCG_03158 8.1e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
LOPFHFCG_03159 3.5e-219 bioI 1.14.14.46 C Cytochrome P450
LOPFHFCG_03160 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LOPFHFCG_03161 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LOPFHFCG_03162 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LOPFHFCG_03163 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LOPFHFCG_03164 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LOPFHFCG_03165 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
LOPFHFCG_03166 2.3e-190 msmR K Transcriptional regulator
LOPFHFCG_03167 2.1e-246 msmE G Bacterial extracellular solute-binding protein
LOPFHFCG_03168 1.5e-169 amyD P ABC transporter
LOPFHFCG_03169 1.5e-144 amyC P ABC transporter (permease)
LOPFHFCG_03170 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LOPFHFCG_03171 2.1e-51 ytwF P Sulfurtransferase
LOPFHFCG_03172 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LOPFHFCG_03173 7.7e-55 ytvB S Protein of unknown function (DUF4257)
LOPFHFCG_03174 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LOPFHFCG_03175 2.1e-211 yttB EGP Major facilitator Superfamily
LOPFHFCG_03176 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
LOPFHFCG_03177 0.0 bceB V ABC transporter (permease)
LOPFHFCG_03178 1.1e-138 bceA V ABC transporter, ATP-binding protein
LOPFHFCG_03179 5.6e-186 T PhoQ Sensor
LOPFHFCG_03180 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_03181 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
LOPFHFCG_03182 3.1e-127 ytrE V ABC transporter, ATP-binding protein
LOPFHFCG_03183 5.9e-148
LOPFHFCG_03184 6.1e-169 P ABC-2 family transporter protein
LOPFHFCG_03185 1.1e-161 ytrB P abc transporter atp-binding protein
LOPFHFCG_03186 5.1e-66 ytrA K GntR family transcriptional regulator
LOPFHFCG_03188 6.7e-41 ytzC S Protein of unknown function (DUF2524)
LOPFHFCG_03189 2.1e-190 yhcC S Fe-S oxidoreductase
LOPFHFCG_03190 3.3e-106 ytqB J Putative rRNA methylase
LOPFHFCG_03191 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
LOPFHFCG_03192 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
LOPFHFCG_03193 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LOPFHFCG_03194 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_03195 0.0 asnB 6.3.5.4 E Asparagine synthase
LOPFHFCG_03196 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LOPFHFCG_03197 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LOPFHFCG_03198 1.2e-38 ytmB S Protein of unknown function (DUF2584)
LOPFHFCG_03199 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LOPFHFCG_03200 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LOPFHFCG_03201 1.4e-144 ytlC P ABC transporter
LOPFHFCG_03202 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LOPFHFCG_03203 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LOPFHFCG_03204 5.4e-63 ytkC S Bacteriophage holin family
LOPFHFCG_03205 2.1e-76 dps P Belongs to the Dps family
LOPFHFCG_03207 3.6e-73 ytkA S YtkA-like
LOPFHFCG_03208 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LOPFHFCG_03209 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LOPFHFCG_03210 3.6e-41 rpmE2 J Ribosomal protein L31
LOPFHFCG_03211 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
LOPFHFCG_03212 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LOPFHFCG_03213 1.1e-24 S Domain of Unknown Function (DUF1540)
LOPFHFCG_03214 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
LOPFHFCG_03215 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LOPFHFCG_03216 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LOPFHFCG_03217 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
LOPFHFCG_03218 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LOPFHFCG_03219 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LOPFHFCG_03220 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LOPFHFCG_03221 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LOPFHFCG_03222 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LOPFHFCG_03223 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
LOPFHFCG_03224 2.6e-132 dksA T COG1734 DnaK suppressor protein
LOPFHFCG_03225 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
LOPFHFCG_03226 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOPFHFCG_03227 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
LOPFHFCG_03228 3.6e-235 ytcC M Glycosyltransferase Family 4
LOPFHFCG_03230 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
LOPFHFCG_03231 1.8e-217 cotSA M Glycosyl transferases group 1
LOPFHFCG_03232 1.8e-206 cotI S Spore coat protein
LOPFHFCG_03233 9.9e-77 tspO T membrane
LOPFHFCG_03234 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LOPFHFCG_03235 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
LOPFHFCG_03236 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
LOPFHFCG_03237 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LOPFHFCG_03238 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LOPFHFCG_03247 7.8e-08
LOPFHFCG_03248 1.3e-09
LOPFHFCG_03255 2e-08
LOPFHFCG_03260 3.4e-39 S COG NOG14552 non supervised orthologous group
LOPFHFCG_03261 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
LOPFHFCG_03262 3.4e-94 M1-753 M FR47-like protein
LOPFHFCG_03263 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
LOPFHFCG_03264 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
LOPFHFCG_03265 3.9e-84 yuaE S DinB superfamily
LOPFHFCG_03266 7.9e-108 yuaD
LOPFHFCG_03267 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
LOPFHFCG_03268 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LOPFHFCG_03269 1.1e-95 yuaC K Belongs to the GbsR family
LOPFHFCG_03270 2.2e-91 yuaB
LOPFHFCG_03271 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
LOPFHFCG_03272 5.4e-237 ktrB P Potassium
LOPFHFCG_03273 1e-38 yiaA S yiaA/B two helix domain
LOPFHFCG_03274 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LOPFHFCG_03275 6.2e-277 yubD P Major Facilitator Superfamily
LOPFHFCG_03276 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
LOPFHFCG_03278 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LOPFHFCG_03279 6.3e-197 yubA S transporter activity
LOPFHFCG_03280 3.3e-183 ygjR S Oxidoreductase
LOPFHFCG_03281 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
LOPFHFCG_03282 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
LOPFHFCG_03283 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
LOPFHFCG_03284 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
LOPFHFCG_03285 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
LOPFHFCG_03286 5.1e-239 mcpA NT chemotaxis protein
LOPFHFCG_03287 2.2e-295 mcpA NT chemotaxis protein
LOPFHFCG_03288 1.5e-222 mcpA NT chemotaxis protein
LOPFHFCG_03289 3.2e-225 mcpA NT chemotaxis protein
LOPFHFCG_03290 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
LOPFHFCG_03291 1e-35
LOPFHFCG_03292 2.1e-72 yugU S Uncharacterised protein family UPF0047
LOPFHFCG_03293 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
LOPFHFCG_03294 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
LOPFHFCG_03295 1.4e-116 yugP S Zn-dependent protease
LOPFHFCG_03296 4.6e-39
LOPFHFCG_03297 1.1e-53 mstX S Membrane-integrating protein Mistic
LOPFHFCG_03298 1.7e-182 yugO P COG1226 Kef-type K transport systems
LOPFHFCG_03299 1.3e-72 yugN S YugN-like family
LOPFHFCG_03301 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
LOPFHFCG_03302 2.8e-229 yugK C Dehydrogenase
LOPFHFCG_03303 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
LOPFHFCG_03304 1.1e-34 yuzA S Domain of unknown function (DUF378)
LOPFHFCG_03305 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
LOPFHFCG_03306 4.3e-200 yugH 2.6.1.1 E Aminotransferase
LOPFHFCG_03307 1.6e-85 alaR K Transcriptional regulator
LOPFHFCG_03308 1e-156 yugF I Hydrolase
LOPFHFCG_03309 9.8e-42 yugE S Domain of unknown function (DUF1871)
LOPFHFCG_03310 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LOPFHFCG_03311 7.8e-233 T PhoQ Sensor
LOPFHFCG_03312 2e-70 kapB G Kinase associated protein B
LOPFHFCG_03313 1.9e-115 kapD L the KinA pathway to sporulation
LOPFHFCG_03315 3.5e-186 yuxJ EGP Major facilitator Superfamily
LOPFHFCG_03316 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
LOPFHFCG_03317 6.3e-75 yuxK S protein conserved in bacteria
LOPFHFCG_03318 6.3e-78 yufK S Family of unknown function (DUF5366)
LOPFHFCG_03319 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LOPFHFCG_03320 1.5e-124 dcuR T COG4565 Response regulator of citrate malate metabolism
LOPFHFCG_03321 6.7e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LOPFHFCG_03322 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LOPFHFCG_03323 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
LOPFHFCG_03324 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
LOPFHFCG_03325 1.3e-233 maeN C COG3493 Na citrate symporter
LOPFHFCG_03326 3.2e-14
LOPFHFCG_03327 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LOPFHFCG_03328 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOPFHFCG_03329 3.4e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOPFHFCG_03330 3.9e-260 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOPFHFCG_03331 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOPFHFCG_03332 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LOPFHFCG_03333 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
LOPFHFCG_03334 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
LOPFHFCG_03335 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOPFHFCG_03336 0.0 comP 2.7.13.3 T Histidine kinase
LOPFHFCG_03338 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
LOPFHFCG_03340 1.1e-22 yuzC
LOPFHFCG_03341 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
LOPFHFCG_03342 1e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LOPFHFCG_03343 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
LOPFHFCG_03344 1.8e-66 yueI S Protein of unknown function (DUF1694)
LOPFHFCG_03345 7.4e-39 yueH S YueH-like protein
LOPFHFCG_03346 2.5e-30 yueG S Spore germination protein gerPA/gerPF
LOPFHFCG_03347 3.2e-190 yueF S transporter activity
LOPFHFCG_03348 6.1e-72 S Protein of unknown function (DUF2283)
LOPFHFCG_03349 4.8e-96 yueE S phosphohydrolase
LOPFHFCG_03350 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_03351 6.6e-65 yueC S Family of unknown function (DUF5383)
LOPFHFCG_03352 0.0 esaA S type VII secretion protein EsaA
LOPFHFCG_03353 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LOPFHFCG_03354 2.4e-208 essB S WXG100 protein secretion system (Wss), protein YukC
LOPFHFCG_03355 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
LOPFHFCG_03356 2.8e-45 esxA S Belongs to the WXG100 family
LOPFHFCG_03357 4.2e-228 yukF QT Transcriptional regulator
LOPFHFCG_03358 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LOPFHFCG_03359 1.2e-131 yukJ S Uncharacterized conserved protein (DUF2278)
LOPFHFCG_03360 1.4e-35 mbtH S MbtH-like protein
LOPFHFCG_03361 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_03362 2.2e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
LOPFHFCG_03363 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
LOPFHFCG_03364 1.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
LOPFHFCG_03365 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_03366 1.1e-166 besA S Putative esterase
LOPFHFCG_03367 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
LOPFHFCG_03368 1.1e-93 bioY S Biotin biosynthesis protein
LOPFHFCG_03369 3.9e-211 yuiF S antiporter
LOPFHFCG_03370 1e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LOPFHFCG_03371 1.2e-77 yuiD S protein conserved in bacteria
LOPFHFCG_03372 4.7e-117 yuiC S protein conserved in bacteria
LOPFHFCG_03373 1.9e-26 yuiB S Putative membrane protein
LOPFHFCG_03374 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
LOPFHFCG_03375 1e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
LOPFHFCG_03377 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LOPFHFCG_03378 3.8e-116 paiB K Putative FMN-binding domain
LOPFHFCG_03379 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOPFHFCG_03380 3.7e-63 erpA S Belongs to the HesB IscA family
LOPFHFCG_03381 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LOPFHFCG_03382 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOPFHFCG_03383 3.2e-39 yuzB S Belongs to the UPF0349 family
LOPFHFCG_03384 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
LOPFHFCG_03385 3.5e-57 yuzD S protein conserved in bacteria
LOPFHFCG_03386 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
LOPFHFCG_03387 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
LOPFHFCG_03388 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LOPFHFCG_03389 2.6e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LOPFHFCG_03390 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
LOPFHFCG_03391 2.9e-198 yutH S Spore coat protein
LOPFHFCG_03392 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LOPFHFCG_03393 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LOPFHFCG_03394 1e-75 yutE S Protein of unknown function DUF86
LOPFHFCG_03395 9.7e-48 yutD S protein conserved in bacteria
LOPFHFCG_03396 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LOPFHFCG_03397 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LOPFHFCG_03398 1.7e-195 lytH M Peptidase, M23
LOPFHFCG_03399 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
LOPFHFCG_03400 4.1e-47 yunC S Domain of unknown function (DUF1805)
LOPFHFCG_03401 6e-263 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LOPFHFCG_03402 2e-141 yunE S membrane transporter protein
LOPFHFCG_03403 4.3e-171 yunF S Protein of unknown function DUF72
LOPFHFCG_03404 8.2e-60 yunG
LOPFHFCG_03405 4.7e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LOPFHFCG_03406 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
LOPFHFCG_03407 2e-234 pbuX F Permease family
LOPFHFCG_03408 4.8e-222 pbuX F xanthine
LOPFHFCG_03409 8.3e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
LOPFHFCG_03410 3.2e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
LOPFHFCG_03412 1.6e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LOPFHFCG_03413 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LOPFHFCG_03414 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LOPFHFCG_03415 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
LOPFHFCG_03416 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LOPFHFCG_03418 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LOPFHFCG_03419 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LOPFHFCG_03420 2.4e-169 bsn L Ribonuclease
LOPFHFCG_03421 1.2e-205 msmX P Belongs to the ABC transporter superfamily
LOPFHFCG_03422 1.1e-135 yurK K UTRA
LOPFHFCG_03423 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
LOPFHFCG_03424 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
LOPFHFCG_03425 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
LOPFHFCG_03426 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
LOPFHFCG_03427 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LOPFHFCG_03428 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
LOPFHFCG_03429 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LOPFHFCG_03431 1e-41
LOPFHFCG_03432 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOPFHFCG_03433 3.5e-271 sufB O FeS cluster assembly
LOPFHFCG_03434 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
LOPFHFCG_03435 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LOPFHFCG_03436 1.4e-245 sufD O assembly protein SufD
LOPFHFCG_03437 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LOPFHFCG_03438 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LOPFHFCG_03439 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
LOPFHFCG_03440 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
LOPFHFCG_03441 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LOPFHFCG_03442 2.4e-56 yusD S SCP-2 sterol transfer family
LOPFHFCG_03443 5.6e-55 traF CO Thioredoxin
LOPFHFCG_03444 1.4e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
LOPFHFCG_03445 2.4e-39 yusG S Protein of unknown function (DUF2553)
LOPFHFCG_03446 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LOPFHFCG_03447 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
LOPFHFCG_03448 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
LOPFHFCG_03449 1.6e-216 fadA 2.3.1.16 I Belongs to the thiolase family
LOPFHFCG_03450 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
LOPFHFCG_03451 4.7e-09 S YuzL-like protein
LOPFHFCG_03452 2.2e-165 fadM E Proline dehydrogenase
LOPFHFCG_03453 5.1e-40
LOPFHFCG_03454 3.2e-53 yusN M Coat F domain
LOPFHFCG_03455 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
LOPFHFCG_03456 3.8e-293 yusP P Major facilitator superfamily
LOPFHFCG_03457 8.4e-66 yusQ S Tautomerase enzyme
LOPFHFCG_03458 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_03459 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_03460 2.7e-160 yusT K LysR substrate binding domain
LOPFHFCG_03461 3.8e-47 yusU S Protein of unknown function (DUF2573)
LOPFHFCG_03462 1e-153 yusV 3.6.3.34 HP ABC transporter
LOPFHFCG_03463 5.6e-66 S YusW-like protein
LOPFHFCG_03464 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
LOPFHFCG_03465 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
LOPFHFCG_03466 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_03467 1.2e-79 dps P Ferritin-like domain
LOPFHFCG_03468 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOPFHFCG_03469 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_03470 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
LOPFHFCG_03471 4.3e-158 yuxN K Transcriptional regulator
LOPFHFCG_03472 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LOPFHFCG_03473 2.3e-24 S Protein of unknown function (DUF3970)
LOPFHFCG_03474 1e-244 gerAA EG Spore germination protein
LOPFHFCG_03475 3.8e-196 gerAB E Spore germination protein
LOPFHFCG_03476 2e-176 gerAC S Spore germination B3/ GerAC like, C-terminal
LOPFHFCG_03477 8.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOPFHFCG_03478 1.6e-186 vraS 2.7.13.3 T Histidine kinase
LOPFHFCG_03479 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LOPFHFCG_03480 3.1e-116 liaG S Putative adhesin
LOPFHFCG_03481 4.7e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LOPFHFCG_03482 7.3e-62 liaI S membrane
LOPFHFCG_03483 5.9e-225 yvqJ EGP Major facilitator Superfamily
LOPFHFCG_03484 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
LOPFHFCG_03485 2.1e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LOPFHFCG_03486 8.5e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_03487 6.9e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
LOPFHFCG_03488 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_03489 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
LOPFHFCG_03490 0.0 T PhoQ Sensor
LOPFHFCG_03491 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_03492 4.5e-96 yvrI K RNA polymerase
LOPFHFCG_03493 2.4e-19 S YvrJ protein family
LOPFHFCG_03494 4.7e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
LOPFHFCG_03495 1.3e-64 yvrL S Regulatory protein YrvL
LOPFHFCG_03496 4.1e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
LOPFHFCG_03497 1.6e-123 macB V ABC transporter, ATP-binding protein
LOPFHFCG_03498 2e-174 M Efflux transporter rnd family, mfp subunit
LOPFHFCG_03499 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
LOPFHFCG_03500 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_03501 3.7e-180 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LOPFHFCG_03502 2.6e-177 fhuD P ABC transporter
LOPFHFCG_03503 4.9e-236 yvsH E Arginine ornithine antiporter
LOPFHFCG_03504 6.5e-16 S Small spore protein J (Spore_SspJ)
LOPFHFCG_03505 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
LOPFHFCG_03506 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LOPFHFCG_03507 2.7e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
LOPFHFCG_03508 3.5e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
LOPFHFCG_03509 1.4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
LOPFHFCG_03510 4.2e-155 yvgN S reductase
LOPFHFCG_03511 2.1e-85 yvgO
LOPFHFCG_03512 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
LOPFHFCG_03513 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LOPFHFCG_03514 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LOPFHFCG_03515 0.0 helD 3.6.4.12 L DNA helicase
LOPFHFCG_03516 4.1e-107 yvgT S membrane
LOPFHFCG_03517 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
LOPFHFCG_03518 1.6e-104 bdbD O Thioredoxin
LOPFHFCG_03519 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LOPFHFCG_03520 0.0 copA 3.6.3.54 P P-type ATPase
LOPFHFCG_03521 1.5e-29 copZ P Copper resistance protein CopZ
LOPFHFCG_03522 2.2e-48 csoR S transcriptional
LOPFHFCG_03523 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
LOPFHFCG_03524 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LOPFHFCG_03525 0.0 yvaC S Fusaric acid resistance protein-like
LOPFHFCG_03526 5.7e-73 yvaD S Family of unknown function (DUF5360)
LOPFHFCG_03527 2.8e-55 yvaE P Small Multidrug Resistance protein
LOPFHFCG_03528 4.1e-101 K Bacterial regulatory proteins, tetR family
LOPFHFCG_03529 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_03531 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LOPFHFCG_03532 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LOPFHFCG_03533 5.6e-143 est 3.1.1.1 S Carboxylesterase
LOPFHFCG_03534 2.4e-23 secG U Preprotein translocase subunit SecG
LOPFHFCG_03535 3.7e-153 yvaM S Serine aminopeptidase, S33
LOPFHFCG_03536 7.5e-36 yvzC K Transcriptional
LOPFHFCG_03537 4e-69 K transcriptional
LOPFHFCG_03538 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
LOPFHFCG_03539 2.2e-54 yodB K transcriptional
LOPFHFCG_03540 4.2e-226 NT chemotaxis protein
LOPFHFCG_03541 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LOPFHFCG_03542 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LOPFHFCG_03543 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LOPFHFCG_03544 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LOPFHFCG_03545 8.7e-61 yvbF K Belongs to the GbsR family
LOPFHFCG_03546 7.9e-13 S Sporulation delaying protein SdpA
LOPFHFCG_03547 7.6e-172
LOPFHFCG_03548 4.4e-08
LOPFHFCG_03549 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LOPFHFCG_03550 4.5e-45 sdpR K transcriptional
LOPFHFCG_03551 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LOPFHFCG_03552 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LOPFHFCG_03553 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LOPFHFCG_03554 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LOPFHFCG_03555 1.4e-98 yvbF K Belongs to the GbsR family
LOPFHFCG_03556 6.4e-103 yvbG U UPF0056 membrane protein
LOPFHFCG_03557 8.6e-113 yvbH S YvbH-like oligomerisation region
LOPFHFCG_03558 4.2e-124 exoY M Membrane
LOPFHFCG_03559 0.0 tcaA S response to antibiotic
LOPFHFCG_03560 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
LOPFHFCG_03561 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LOPFHFCG_03562 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LOPFHFCG_03563 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LOPFHFCG_03564 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LOPFHFCG_03565 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LOPFHFCG_03566 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LOPFHFCG_03567 1.6e-252 araE EGP Major facilitator Superfamily
LOPFHFCG_03568 5.5e-203 araR K transcriptional
LOPFHFCG_03569 1.5e-91 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_03570 1.1e-71 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_03571 3.9e-159 yvbU K Transcriptional regulator
LOPFHFCG_03572 5.1e-32 yvbV EG EamA-like transporter family
LOPFHFCG_03573 1.4e-31 yvbV EG EamA-like transporter family
LOPFHFCG_03574 4.5e-47 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_03575 7.4e-26 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_03576 1.5e-35 yvbX S Glycosyl hydrolase
LOPFHFCG_03577 2.4e-31 yvbX S Glycosyl hydrolase
LOPFHFCG_03578 5.8e-49 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LOPFHFCG_03579 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LOPFHFCG_03580 9.5e-88 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LOPFHFCG_03581 3e-90 tcaA S response to antibiotic
LOPFHFCG_03582 1.4e-184 tcaA S response to antibiotic
LOPFHFCG_03583 3.6e-41 tcaA S response to antibiotic
LOPFHFCG_03584 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
LOPFHFCG_03585 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LOPFHFCG_03586 3.7e-145 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LOPFHFCG_03587 5.2e-99 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LOPFHFCG_03588 1.2e-79 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LOPFHFCG_03589 1.4e-30 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LOPFHFCG_03590 1.5e-74 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LOPFHFCG_03591 9.2e-107 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LOPFHFCG_03592 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LOPFHFCG_03593 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LOPFHFCG_03594 1.6e-252 araE EGP Major facilitator Superfamily
LOPFHFCG_03595 5.5e-203 araR K transcriptional
LOPFHFCG_03596 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_03597 3.9e-159 yvbU K Transcriptional regulator
LOPFHFCG_03598 8.5e-157 yvbV EG EamA-like transporter family
LOPFHFCG_03599 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LOPFHFCG_03600 4.3e-197 yvbX S Glycosyl hydrolase
LOPFHFCG_03601 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LOPFHFCG_03602 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LOPFHFCG_03603 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LOPFHFCG_03604 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOPFHFCG_03605 8.9e-201 desK 2.7.13.3 T Histidine kinase
LOPFHFCG_03606 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
LOPFHFCG_03607 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
LOPFHFCG_03608 2.6e-157 rsbQ S Alpha/beta hydrolase family
LOPFHFCG_03609 1.4e-199 rsbU 3.1.3.3 T response regulator
LOPFHFCG_03610 2.6e-252 galA 3.2.1.89 G arabinogalactan
LOPFHFCG_03611 0.0 lacA 3.2.1.23 G beta-galactosidase
LOPFHFCG_03612 3.2e-150 ganQ P transport
LOPFHFCG_03613 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
LOPFHFCG_03614 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
LOPFHFCG_03615 1.8e-184 lacR K Transcriptional regulator
LOPFHFCG_03616 6.6e-111 yvfI K COG2186 Transcriptional regulators
LOPFHFCG_03617 1.4e-309 yvfH C L-lactate permease
LOPFHFCG_03618 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LOPFHFCG_03619 1e-31 yvfG S YvfG protein
LOPFHFCG_03620 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
LOPFHFCG_03621 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LOPFHFCG_03622 6.4e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
LOPFHFCG_03623 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LOPFHFCG_03624 6.1e-253 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOPFHFCG_03625 1.9e-189 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
LOPFHFCG_03626 3.5e-202 epsI GM pyruvyl transferase
LOPFHFCG_03627 6.4e-193 epsH GT2 S Glycosyltransferase like family 2
LOPFHFCG_03628 1.8e-206 epsG S EpsG family
LOPFHFCG_03629 3.2e-217 epsF GT4 M Glycosyl transferases group 1
LOPFHFCG_03630 1.7e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LOPFHFCG_03631 2.6e-219 epsD GT4 M Glycosyl transferase 4-like
LOPFHFCG_03632 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
LOPFHFCG_03633 3.9e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
LOPFHFCG_03634 4e-122 ywqC M biosynthesis protein
LOPFHFCG_03635 3.1e-75 slr K transcriptional
LOPFHFCG_03636 2.8e-279 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
LOPFHFCG_03638 4.6e-93 padC Q Phenolic acid decarboxylase
LOPFHFCG_03639 7.3e-46 MA20_18690 S Protein of unknown function (DUF3237)
LOPFHFCG_03640 6.1e-16 MA20_18690 S Protein of unknown function (DUF3237)
LOPFHFCG_03641 5.4e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LOPFHFCG_03642 3.8e-262 pbpE V Beta-lactamase
LOPFHFCG_03643 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
LOPFHFCG_03644 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
LOPFHFCG_03645 1.8e-295 yveA E amino acid
LOPFHFCG_03646 7.4e-106 yvdT K Transcriptional regulator
LOPFHFCG_03647 6.7e-51 ykkC P Small Multidrug Resistance protein
LOPFHFCG_03648 4.1e-50 sugE P Small Multidrug Resistance protein
LOPFHFCG_03649 3.9e-72 yvdQ S Protein of unknown function (DUF3231)
LOPFHFCG_03650 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
LOPFHFCG_03651 1.5e-183 S Patatin-like phospholipase
LOPFHFCG_03653 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LOPFHFCG_03654 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
LOPFHFCG_03655 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
LOPFHFCG_03656 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
LOPFHFCG_03657 1.2e-158 malA S Protein of unknown function (DUF1189)
LOPFHFCG_03658 7.8e-149 malD P transport
LOPFHFCG_03659 1.3e-243 malC P COG1175 ABC-type sugar transport systems, permease components
LOPFHFCG_03660 9e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
LOPFHFCG_03661 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
LOPFHFCG_03662 6.1e-174 yvdE K Transcriptional regulator
LOPFHFCG_03663 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
LOPFHFCG_03664 1.5e-29 yvdC S MazG nucleotide pyrophosphohydrolase domain
LOPFHFCG_03665 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
LOPFHFCG_03666 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LOPFHFCG_03667 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LOPFHFCG_03668 0.0 yxdM V ABC transporter (permease)
LOPFHFCG_03669 5.6e-141 yvcR V ABC transporter, ATP-binding protein
LOPFHFCG_03670 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
LOPFHFCG_03671 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_03672 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
LOPFHFCG_03673 1.6e-36 crh G Phosphocarrier protein Chr
LOPFHFCG_03674 4.1e-170 whiA K May be required for sporulation
LOPFHFCG_03675 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LOPFHFCG_03676 5.7e-166 rapZ S Displays ATPase and GTPase activities
LOPFHFCG_03677 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LOPFHFCG_03678 2.8e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LOPFHFCG_03679 8.1e-98 usp CBM50 M protein conserved in bacteria
LOPFHFCG_03680 2.4e-278 S COG0457 FOG TPR repeat
LOPFHFCG_03681 0.0 msbA2 3.6.3.44 V ABC transporter
LOPFHFCG_03683 0.0
LOPFHFCG_03684 1.4e-74
LOPFHFCG_03685 2.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
LOPFHFCG_03686 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LOPFHFCG_03687 1.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LOPFHFCG_03688 8.1e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LOPFHFCG_03689 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LOPFHFCG_03690 3.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LOPFHFCG_03691 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LOPFHFCG_03692 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LOPFHFCG_03693 4.5e-140 yvpB NU protein conserved in bacteria
LOPFHFCG_03694 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
LOPFHFCG_03695 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
LOPFHFCG_03696 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LOPFHFCG_03697 4.5e-161 yvoD P COG0370 Fe2 transport system protein B
LOPFHFCG_03698 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LOPFHFCG_03699 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LOPFHFCG_03700 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LOPFHFCG_03701 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LOPFHFCG_03702 3.6e-134 yvoA K transcriptional
LOPFHFCG_03703 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
LOPFHFCG_03704 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
LOPFHFCG_03705 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
LOPFHFCG_03706 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
LOPFHFCG_03707 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
LOPFHFCG_03708 2.7e-203 yvmA EGP Major facilitator Superfamily
LOPFHFCG_03709 1.2e-50 yvlD S Membrane
LOPFHFCG_03710 2.6e-26 pspB KT PspC domain
LOPFHFCG_03711 3.4e-168 yvlB S Putative adhesin
LOPFHFCG_03712 8e-49 yvlA
LOPFHFCG_03713 6.7e-34 yvkN
LOPFHFCG_03714 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LOPFHFCG_03715 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LOPFHFCG_03716 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LOPFHFCG_03717 1.2e-30 csbA S protein conserved in bacteria
LOPFHFCG_03718 0.0 yvkC 2.7.9.2 GT Phosphotransferase
LOPFHFCG_03719 7e-101 yvkB K Transcriptional regulator
LOPFHFCG_03720 9.6e-226 yvkA EGP Major facilitator Superfamily
LOPFHFCG_03721 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOPFHFCG_03722 5.3e-56 swrA S Swarming motility protein
LOPFHFCG_03723 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
LOPFHFCG_03724 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LOPFHFCG_03725 2.7e-123 ftsE D cell division ATP-binding protein FtsE
LOPFHFCG_03726 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
LOPFHFCG_03727 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
LOPFHFCG_03728 3.9e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LOPFHFCG_03729 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LOPFHFCG_03730 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LOPFHFCG_03731 4.6e-51
LOPFHFCG_03732 1.9e-08 fliT S bacterial-type flagellum organization
LOPFHFCG_03733 6.5e-69 fliS N flagellar protein FliS
LOPFHFCG_03734 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LOPFHFCG_03735 1.2e-55 flaG N flagellar protein FlaG
LOPFHFCG_03736 1.4e-122 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LOPFHFCG_03737 5.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LOPFHFCG_03738 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LOPFHFCG_03739 1.3e-49 yviE
LOPFHFCG_03740 1.3e-154 flgL N Belongs to the bacterial flagellin family
LOPFHFCG_03741 1.6e-264 flgK N flagellar hook-associated protein
LOPFHFCG_03742 2.4e-78 flgN NOU FlgN protein
LOPFHFCG_03743 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
LOPFHFCG_03744 7e-74 yvyF S flagellar protein
LOPFHFCG_03745 2.7e-129 comFC S Phosphoribosyl transferase domain
LOPFHFCG_03746 5.7e-46 comFB S Late competence development protein ComFB
LOPFHFCG_03747 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LOPFHFCG_03748 7.3e-155 degV S protein conserved in bacteria
LOPFHFCG_03749 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LOPFHFCG_03750 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LOPFHFCG_03751 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LOPFHFCG_03752 6e-163 yvhJ K Transcriptional regulator
LOPFHFCG_03753 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LOPFHFCG_03754 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
LOPFHFCG_03755 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
LOPFHFCG_03756 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
LOPFHFCG_03757 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
LOPFHFCG_03758 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOPFHFCG_03759 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
LOPFHFCG_03760 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LOPFHFCG_03761 2.7e-78 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LOPFHFCG_03762 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LOPFHFCG_03763 0.0 lytB 3.5.1.28 D Stage II sporulation protein
LOPFHFCG_03764 6e-38
LOPFHFCG_03765 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LOPFHFCG_03766 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LOPFHFCG_03767 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LOPFHFCG_03768 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
LOPFHFCG_03769 8.1e-257 ggaA M Glycosyltransferase like family 2
LOPFHFCG_03771 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LOPFHFCG_03772 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LOPFHFCG_03773 1.1e-150 tagG GM Transport permease protein
LOPFHFCG_03774 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LOPFHFCG_03775 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
LOPFHFCG_03776 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
LOPFHFCG_03777 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LOPFHFCG_03778 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LOPFHFCG_03779 1.2e-260
LOPFHFCG_03780 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LOPFHFCG_03781 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
LOPFHFCG_03782 3.5e-266 gerBA EG Spore germination protein
LOPFHFCG_03783 7.5e-200 gerBB E Spore germination protein
LOPFHFCG_03784 7.6e-216 gerAC S Spore germination protein
LOPFHFCG_03785 1.9e-248 ywtG EGP Major facilitator Superfamily
LOPFHFCG_03786 8.4e-171 ywtF K Transcriptional regulator
LOPFHFCG_03787 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
LOPFHFCG_03788 7.7e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LOPFHFCG_03789 3.6e-21 ywtC
LOPFHFCG_03790 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LOPFHFCG_03791 8.6e-70 pgsC S biosynthesis protein
LOPFHFCG_03792 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
LOPFHFCG_03793 3e-176 rbsR K transcriptional
LOPFHFCG_03794 1.3e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LOPFHFCG_03795 2.6e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LOPFHFCG_03796 5.2e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LOPFHFCG_03797 6e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
LOPFHFCG_03798 4.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
LOPFHFCG_03799 7.3e-92 batE T Sh3 type 3 domain protein
LOPFHFCG_03800 8e-48 ywsA S Protein of unknown function (DUF3892)
LOPFHFCG_03801 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
LOPFHFCG_03802 4.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LOPFHFCG_03803 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LOPFHFCG_03804 2.5e-169 alsR K LysR substrate binding domain
LOPFHFCG_03805 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LOPFHFCG_03806 1.1e-124 ywrJ
LOPFHFCG_03807 2.6e-123 cotB
LOPFHFCG_03808 1.8e-206 cotH M Spore Coat
LOPFHFCG_03809 1.3e-12
LOPFHFCG_03810 6.9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LOPFHFCG_03811 5e-54 S Domain of unknown function (DUF4181)
LOPFHFCG_03812 9.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LOPFHFCG_03813 8e-82 ywrC K Transcriptional regulator
LOPFHFCG_03814 1.6e-103 ywrB P Chromate transporter
LOPFHFCG_03815 1.4e-87 ywrA P COG2059 Chromate transport protein ChrA
LOPFHFCG_03817 4.8e-99 ywqN S NAD(P)H-dependent
LOPFHFCG_03818 1.4e-161 K Transcriptional regulator
LOPFHFCG_03819 5.4e-131 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LOPFHFCG_03820 1.7e-52 S MORN repeat variant
LOPFHFCG_03821 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
LOPFHFCG_03822 1.3e-38 ywqI S Family of unknown function (DUF5344)
LOPFHFCG_03823 3.3e-15 S Domain of unknown function (DUF5082)
LOPFHFCG_03824 3.4e-154 ywqG S Domain of unknown function (DUF1963)
LOPFHFCG_03825 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LOPFHFCG_03826 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
LOPFHFCG_03827 3.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
LOPFHFCG_03828 2e-116 ywqC M biosynthesis protein
LOPFHFCG_03829 1.2e-17
LOPFHFCG_03830 1e-306 ywqB S SWIM zinc finger
LOPFHFCG_03831 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LOPFHFCG_03832 5.7e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
LOPFHFCG_03833 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
LOPFHFCG_03834 2.2e-57 ssbB L Single-stranded DNA-binding protein
LOPFHFCG_03835 1.2e-29 ywpG
LOPFHFCG_03836 6.9e-66 ywpF S YwpF-like protein
LOPFHFCG_03837 5.2e-50 srtA 3.4.22.70 M Sortase family
LOPFHFCG_03838 2.1e-144 ywpD T Histidine kinase
LOPFHFCG_03839 1.1e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LOPFHFCG_03840 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LOPFHFCG_03841 7.5e-197 S aspartate phosphatase
LOPFHFCG_03842 2.6e-141 flhP N flagellar basal body
LOPFHFCG_03843 3.2e-123 flhO N flagellar basal body
LOPFHFCG_03844 3.5e-180 mbl D Rod shape-determining protein
LOPFHFCG_03845 3e-44 spoIIID K Stage III sporulation protein D
LOPFHFCG_03846 2.1e-70 ywoH K COG1846 Transcriptional regulators
LOPFHFCG_03847 3.9e-210 ywoG EGP Major facilitator Superfamily
LOPFHFCG_03848 9.8e-229 ywoF P Right handed beta helix region
LOPFHFCG_03849 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
LOPFHFCG_03850 2.4e-240 ywoD EGP Major facilitator superfamily
LOPFHFCG_03851 3.4e-103 phzA Q Isochorismatase family
LOPFHFCG_03852 1.7e-76
LOPFHFCG_03853 1.3e-224 amt P Ammonium transporter
LOPFHFCG_03854 1.6e-58 nrgB K Belongs to the P(II) protein family
LOPFHFCG_03855 7.7e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
LOPFHFCG_03856 5.6e-71 ywnJ S VanZ like family
LOPFHFCG_03857 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
LOPFHFCG_03858 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
LOPFHFCG_03859 1.3e-08 ywnC S Family of unknown function (DUF5362)
LOPFHFCG_03860 1.5e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
LOPFHFCG_03861 2.2e-70 ywnF S Family of unknown function (DUF5392)
LOPFHFCG_03862 4.6e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOPFHFCG_03863 2.1e-140 mta K transcriptional
LOPFHFCG_03864 2.6e-59 ywnC S Family of unknown function (DUF5362)
LOPFHFCG_03865 9.9e-112 ywnB S NAD(P)H-binding
LOPFHFCG_03866 1.7e-64 ywnA K Transcriptional regulator
LOPFHFCG_03867 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LOPFHFCG_03868 2.2e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LOPFHFCG_03869 1.8e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LOPFHFCG_03871 1.4e-10 csbD K CsbD-like
LOPFHFCG_03872 1.1e-83 ywmF S Peptidase M50
LOPFHFCG_03873 2.7e-104 S response regulator aspartate phosphatase
LOPFHFCG_03874 7.7e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LOPFHFCG_03875 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LOPFHFCG_03877 1.4e-119 ywmD S protein containing a von Willebrand factor type A (vWA) domain
LOPFHFCG_03878 9.6e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
LOPFHFCG_03879 7.5e-178 spoIID D Stage II sporulation protein D
LOPFHFCG_03880 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOPFHFCG_03881 9e-133 ywmB S TATA-box binding
LOPFHFCG_03882 1.3e-32 ywzB S membrane
LOPFHFCG_03883 1.4e-86 ywmA
LOPFHFCG_03884 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LOPFHFCG_03885 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LOPFHFCG_03886 1.9e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LOPFHFCG_03887 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LOPFHFCG_03888 1.5e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LOPFHFCG_03889 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LOPFHFCG_03890 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LOPFHFCG_03891 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
LOPFHFCG_03892 2.5e-62 atpI S ATP synthase
LOPFHFCG_03893 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LOPFHFCG_03894 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LOPFHFCG_03895 7.2e-95 ywlG S Belongs to the UPF0340 family
LOPFHFCG_03896 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
LOPFHFCG_03897 1.9e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LOPFHFCG_03898 4.9e-91 mntP P Probably functions as a manganese efflux pump
LOPFHFCG_03899 1.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LOPFHFCG_03900 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
LOPFHFCG_03901 6.1e-112 spoIIR S stage II sporulation protein R
LOPFHFCG_03902 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
LOPFHFCG_03904 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LOPFHFCG_03905 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LOPFHFCG_03906 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOPFHFCG_03907 1.2e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LOPFHFCG_03908 8.6e-160 ywkB S Membrane transport protein
LOPFHFCG_03909 0.0 sfcA 1.1.1.38 C malic enzyme
LOPFHFCG_03910 7e-104 tdk 2.7.1.21 F thymidine kinase
LOPFHFCG_03911 1.1e-32 rpmE J Binds the 23S rRNA
LOPFHFCG_03912 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LOPFHFCG_03913 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
LOPFHFCG_03914 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LOPFHFCG_03916 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LOPFHFCG_03917 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
LOPFHFCG_03918 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
LOPFHFCG_03919 2.4e-92 ywjG S Domain of unknown function (DUF2529)
LOPFHFCG_03920 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LOPFHFCG_03921 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LOPFHFCG_03922 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
LOPFHFCG_03923 0.0 fadF C COG0247 Fe-S oxidoreductase
LOPFHFCG_03924 1.1e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LOPFHFCG_03925 5.6e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LOPFHFCG_03926 1.1e-95 ywjB H RibD C-terminal domain
LOPFHFCG_03927 2.8e-271 ywjA V ABC transporter
LOPFHFCG_03928 8.3e-30 ywjA V ABC transporter
LOPFHFCG_03929 3.5e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LOPFHFCG_03930 9.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
LOPFHFCG_03931 3.6e-94 narJ 1.7.5.1 C nitrate reductase
LOPFHFCG_03932 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
LOPFHFCG_03933 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOPFHFCG_03934 7e-86 arfM T cyclic nucleotide binding
LOPFHFCG_03935 1.7e-139 ywiC S YwiC-like protein
LOPFHFCG_03936 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
LOPFHFCG_03937 1e-213 narK P COG2223 Nitrate nitrite transporter
LOPFHFCG_03938 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LOPFHFCG_03939 2.3e-72 ywiB S protein conserved in bacteria
LOPFHFCG_03940 1e-07 S Bacteriocin subtilosin A
LOPFHFCG_03941 4.9e-270 C Fe-S oxidoreductases
LOPFHFCG_03943 1.3e-131 cbiO V ABC transporter
LOPFHFCG_03944 2e-231 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
LOPFHFCG_03945 1.4e-215 2.7.1.26, 2.7.7.2 L Peptidase, M16
LOPFHFCG_03946 5.2e-245 L Peptidase, M16
LOPFHFCG_03948 6.2e-244 ywhL CO amine dehydrogenase activity
LOPFHFCG_03949 1.1e-189 ywhK CO amine dehydrogenase activity
LOPFHFCG_03950 3.1e-79 S aspartate phosphatase
LOPFHFCG_03952 1.2e-65 ywhH S Aminoacyl-tRNA editing domain
LOPFHFCG_03953 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
LOPFHFCG_03954 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LOPFHFCG_03955 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LOPFHFCG_03956 5.2e-95 ywhD S YwhD family
LOPFHFCG_03957 5.1e-119 ywhC S Peptidase family M50
LOPFHFCG_03958 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LOPFHFCG_03959 3.3e-71 ywhA K Transcriptional regulator
LOPFHFCG_03960 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LOPFHFCG_03962 2.6e-242 mmr U Major Facilitator Superfamily
LOPFHFCG_03963 2.8e-79 yffB K Transcriptional regulator
LOPFHFCG_03964 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
LOPFHFCG_03965 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
LOPFHFCG_03966 3.1e-36 ywzC S Belongs to the UPF0741 family
LOPFHFCG_03967 1.6e-111 rsfA_1
LOPFHFCG_03968 5.2e-159 ywfM EG EamA-like transporter family
LOPFHFCG_03969 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LOPFHFCG_03970 9.2e-164 cysL K Transcriptional regulator
LOPFHFCG_03971 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
LOPFHFCG_03972 1.1e-146 ywfI C May function as heme-dependent peroxidase
LOPFHFCG_03973 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
LOPFHFCG_03974 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
LOPFHFCG_03975 2.9e-210 bacE EGP Major facilitator Superfamily
LOPFHFCG_03976 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LOPFHFCG_03977 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_03978 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LOPFHFCG_03979 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LOPFHFCG_03980 4.6e-206 ywfA EGP Major facilitator Superfamily
LOPFHFCG_03981 5.1e-251 lysP E amino acid
LOPFHFCG_03982 0.0 rocB E arginine degradation protein
LOPFHFCG_03983 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LOPFHFCG_03984 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LOPFHFCG_03985 7.5e-77
LOPFHFCG_03986 7.8e-55 spsL 5.1.3.13 M Spore Coat
LOPFHFCG_03987 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LOPFHFCG_03988 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LOPFHFCG_03989 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LOPFHFCG_03990 1.7e-190 spsG M Spore Coat
LOPFHFCG_03991 9.7e-132 spsF M Spore Coat
LOPFHFCG_03992 3.2e-214 spsE 2.5.1.56 M acid synthase
LOPFHFCG_03993 4e-164 spsD 2.3.1.210 K Spore Coat
LOPFHFCG_03994 4.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
LOPFHFCG_03995 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
LOPFHFCG_03996 2.8e-145 spsA M Spore Coat
LOPFHFCG_03997 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LOPFHFCG_03998 4.3e-59 ywdK S small membrane protein
LOPFHFCG_03999 1.3e-238 ywdJ F Xanthine uracil
LOPFHFCG_04000 7.7e-49 ywdI S Family of unknown function (DUF5327)
LOPFHFCG_04001 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LOPFHFCG_04002 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LOPFHFCG_04003 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
LOPFHFCG_04005 1.4e-113 ywdD
LOPFHFCG_04006 1.3e-57 pex K Transcriptional regulator PadR-like family
LOPFHFCG_04007 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LOPFHFCG_04008 2e-28 ywdA
LOPFHFCG_04009 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
LOPFHFCG_04010 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOPFHFCG_04011 1e-139 focA P Formate/nitrite transporter
LOPFHFCG_04012 2.4e-150 sacT K transcriptional antiterminator
LOPFHFCG_04014 0.0 vpr O Belongs to the peptidase S8 family
LOPFHFCG_04015 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_04016 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
LOPFHFCG_04017 2.9e-202 rodA D Belongs to the SEDS family
LOPFHFCG_04018 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
LOPFHFCG_04019 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LOPFHFCG_04020 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LOPFHFCG_04021 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LOPFHFCG_04022 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LOPFHFCG_04023 1e-35 ywzA S membrane
LOPFHFCG_04024 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LOPFHFCG_04025 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LOPFHFCG_04026 9.5e-60 gtcA S GtrA-like protein
LOPFHFCG_04027 2.2e-122 ywcC K transcriptional regulator
LOPFHFCG_04029 9.8e-49 ywcB S Protein of unknown function, DUF485
LOPFHFCG_04030 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LOPFHFCG_04031 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LOPFHFCG_04032 2.6e-225 ywbN P Dyp-type peroxidase family protein
LOPFHFCG_04033 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
LOPFHFCG_04034 4.5e-253 P COG0672 High-affinity Fe2 Pb2 permease
LOPFHFCG_04035 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LOPFHFCG_04036 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LOPFHFCG_04037 4.3e-153 ywbI K Transcriptional regulator
LOPFHFCG_04038 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LOPFHFCG_04039 2.3e-111 ywbG M effector of murein hydrolase
LOPFHFCG_04040 7.3e-209 ywbF EGP Major facilitator Superfamily
LOPFHFCG_04041 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
LOPFHFCG_04042 1e-218 ywbD 2.1.1.191 J Methyltransferase
LOPFHFCG_04043 9.9e-67 ywbC 4.4.1.5 E glyoxalase
LOPFHFCG_04044 2e-126 ywbB S Protein of unknown function (DUF2711)
LOPFHFCG_04045 2.5e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOPFHFCG_04046 1.4e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
LOPFHFCG_04047 5.4e-240 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOPFHFCG_04048 1.2e-152 sacY K transcriptional antiterminator
LOPFHFCG_04049 1.3e-167 gspA M General stress
LOPFHFCG_04050 7.4e-124 ywaF S Integral membrane protein
LOPFHFCG_04051 2.3e-87 ywaE K Transcriptional regulator
LOPFHFCG_04052 6.4e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LOPFHFCG_04053 5.7e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
LOPFHFCG_04054 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
LOPFHFCG_04055 6e-44 tnpIS3 L Transposase
LOPFHFCG_04056 1.5e-134 L Integrase core domain
LOPFHFCG_04057 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LOPFHFCG_04058 5e-14 S D-Ala-teichoic acid biosynthesis protein
LOPFHFCG_04059 5.3e-289 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_04060 1.2e-232 dltB M membrane protein involved in D-alanine export
LOPFHFCG_04061 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LOPFHFCG_04062 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LOPFHFCG_04063 8.6e-47 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_04064 7.8e-64 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_04065 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LOPFHFCG_04066 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LOPFHFCG_04067 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
LOPFHFCG_04068 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LOPFHFCG_04069 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
LOPFHFCG_04070 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
LOPFHFCG_04071 9.3e-19 yxzF
LOPFHFCG_04072 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LOPFHFCG_04073 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LOPFHFCG_04074 2.6e-214 yxlH EGP Major facilitator Superfamily
LOPFHFCG_04075 1.3e-137 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LOPFHFCG_04076 9.7e-166 yxlF V ABC transporter, ATP-binding protein
LOPFHFCG_04077 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
LOPFHFCG_04078 2.2e-28
LOPFHFCG_04079 5.6e-47 yxlC S Family of unknown function (DUF5345)
LOPFHFCG_04080 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
LOPFHFCG_04081 5e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
LOPFHFCG_04082 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LOPFHFCG_04083 0.0 cydD V ATP-binding protein
LOPFHFCG_04084 0.0 cydD V ATP-binding
LOPFHFCG_04085 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
LOPFHFCG_04086 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
LOPFHFCG_04087 4.7e-228 cimH C COG3493 Na citrate symporter
LOPFHFCG_04088 4.7e-311 3.4.24.84 O Peptidase family M48
LOPFHFCG_04090 2.8e-154 yxkH G Polysaccharide deacetylase
LOPFHFCG_04091 5.9e-205 msmK P Belongs to the ABC transporter superfamily
LOPFHFCG_04092 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
LOPFHFCG_04093 9.7e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOPFHFCG_04094 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LOPFHFCG_04095 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LOPFHFCG_04096 5.9e-77 S Protein of unknown function (DUF1453)
LOPFHFCG_04097 3.6e-179 yxjM T Signal transduction histidine kinase
LOPFHFCG_04098 1.9e-113 K helix_turn_helix, Lux Regulon
LOPFHFCG_04099 5.2e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LOPFHFCG_04102 1e-87 yxjI S LURP-one-related
LOPFHFCG_04103 3.9e-220 yxjG 2.1.1.14 E Methionine synthase
LOPFHFCG_04104 3.1e-217 yxjG 2.1.1.14 E Methionine synthase
LOPFHFCG_04105 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LOPFHFCG_04106 1.7e-114 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LOPFHFCG_04107 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LOPFHFCG_04108 2.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
LOPFHFCG_04109 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
LOPFHFCG_04110 2.1e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOPFHFCG_04111 1.5e-102 T Domain of unknown function (DUF4163)
LOPFHFCG_04112 3e-47 yxiS
LOPFHFCG_04113 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
LOPFHFCG_04114 6.6e-224 citH C Citrate transporter
LOPFHFCG_04115 3.6e-142 exoK GH16 M licheninase activity
LOPFHFCG_04116 8.3e-151 licT K transcriptional antiterminator
LOPFHFCG_04117 6.2e-112
LOPFHFCG_04118 7.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
LOPFHFCG_04119 2.5e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LOPFHFCG_04120 8.6e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
LOPFHFCG_04123 3.5e-43 yxiJ S YxiJ-like protein
LOPFHFCG_04126 3.2e-32
LOPFHFCG_04127 3.5e-93 yxiI S Protein of unknown function (DUF2716)
LOPFHFCG_04128 9.4e-142
LOPFHFCG_04129 8.3e-13 yxiG
LOPFHFCG_04130 5.3e-16 yxiG
LOPFHFCG_04131 1.9e-38 S Protein of unknown function (DUF2750)
LOPFHFCG_04132 3.4e-52 yxxG
LOPFHFCG_04133 4.3e-68 yxiG
LOPFHFCG_04134 4.9e-76
LOPFHFCG_04135 4.7e-94 S Protein of unknown function (DUF4240)
LOPFHFCG_04136 4.5e-141
LOPFHFCG_04138 7e-55
LOPFHFCG_04139 1.6e-80 wapA M COG3209 Rhs family protein
LOPFHFCG_04140 4.1e-14 yxiJ S YxiJ-like protein
LOPFHFCG_04141 0.0 wapA M COG3209 Rhs family protein
LOPFHFCG_04142 1.8e-162 yxxF EG EamA-like transporter family
LOPFHFCG_04143 1.2e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LOPFHFCG_04144 2.1e-121 1.14.11.45 E 2OG-Fe dioxygenase
LOPFHFCG_04145 1.1e-72 yxiE T Belongs to the universal stress protein A family
LOPFHFCG_04146 2.9e-173 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOPFHFCG_04147 6.8e-93 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOPFHFCG_04148 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LOPFHFCG_04149 3.6e-51
LOPFHFCG_04150 2.2e-78 S SMI1 / KNR4 family
LOPFHFCG_04151 0.0 S nuclease activity
LOPFHFCG_04152 3.6e-39 yxiC S Family of unknown function (DUF5344)
LOPFHFCG_04153 2.1e-21 S Domain of unknown function (DUF5082)
LOPFHFCG_04154 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LOPFHFCG_04155 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LOPFHFCG_04156 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
LOPFHFCG_04157 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LOPFHFCG_04158 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
LOPFHFCG_04159 1.3e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LOPFHFCG_04160 6.1e-252 lysP E amino acid
LOPFHFCG_04161 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LOPFHFCG_04162 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LOPFHFCG_04163 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LOPFHFCG_04164 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LOPFHFCG_04165 3e-153 yxxB S Domain of Unknown Function (DUF1206)
LOPFHFCG_04166 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
LOPFHFCG_04167 2e-255 yxeQ S MmgE/PrpD family
LOPFHFCG_04168 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
LOPFHFCG_04169 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
LOPFHFCG_04170 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
LOPFHFCG_04171 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
LOPFHFCG_04172 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LOPFHFCG_04173 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LOPFHFCG_04175 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LOPFHFCG_04176 6.2e-151 yidA S hydrolases of the HAD superfamily
LOPFHFCG_04179 1.3e-20 yxeE
LOPFHFCG_04180 1.9e-16 yxeD
LOPFHFCG_04181 7.2e-68
LOPFHFCG_04182 2.3e-176 fhuD P ABC transporter
LOPFHFCG_04183 1.5e-58 yxeA S Protein of unknown function (DUF1093)
LOPFHFCG_04184 6.9e-306 yxdM V ABC transporter (permease)
LOPFHFCG_04185 3.4e-68 yxdL V ABC transporter, ATP-binding protein
LOPFHFCG_04186 1.3e-51 yxdL V ABC transporter, ATP-binding protein
LOPFHFCG_04187 7.6e-180 T PhoQ Sensor
LOPFHFCG_04188 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_04189 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LOPFHFCG_04190 3.3e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LOPFHFCG_04191 3.3e-166 iolH G Xylose isomerase-like TIM barrel
LOPFHFCG_04192 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LOPFHFCG_04193 4e-232 iolF EGP Major facilitator Superfamily
LOPFHFCG_04194 3.6e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LOPFHFCG_04195 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LOPFHFCG_04196 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LOPFHFCG_04197 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LOPFHFCG_04198 3.9e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LOPFHFCG_04199 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
LOPFHFCG_04200 3.7e-176 iolS C Aldo keto reductase
LOPFHFCG_04202 8.3e-48 yxcD S Protein of unknown function (DUF2653)
LOPFHFCG_04203 2.3e-246 csbC EGP Major facilitator Superfamily
LOPFHFCG_04204 0.0 htpG O Molecular chaperone. Has ATPase activity
LOPFHFCG_04206 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
LOPFHFCG_04207 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
LOPFHFCG_04208 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LOPFHFCG_04209 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
LOPFHFCG_04210 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
LOPFHFCG_04211 3.3e-127 yxbB Q Met-10+ like-protein
LOPFHFCG_04212 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
LOPFHFCG_04213 1.1e-86 yxnB
LOPFHFCG_04214 0.0 asnB 6.3.5.4 E Asparagine synthase
LOPFHFCG_04215 7.6e-214 yxaM U MFS_1 like family
LOPFHFCG_04216 6.8e-93 S PQQ-like domain
LOPFHFCG_04217 3.5e-65 S Family of unknown function (DUF5391)
LOPFHFCG_04218 1.1e-75 yxaI S membrane protein domain
LOPFHFCG_04219 1.4e-228 P Protein of unknown function (DUF418)
LOPFHFCG_04220 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
LOPFHFCG_04221 7.1e-101 yxaF K Transcriptional regulator
LOPFHFCG_04222 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LOPFHFCG_04223 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
LOPFHFCG_04224 5.2e-50 S LrgA family
LOPFHFCG_04225 2.6e-118 yxaC M effector of murein hydrolase
LOPFHFCG_04226 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
LOPFHFCG_04227 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LOPFHFCG_04228 7.3e-127 gntR K transcriptional
LOPFHFCG_04229 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
LOPFHFCG_04230 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
LOPFHFCG_04231 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LOPFHFCG_04232 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
LOPFHFCG_04233 3.8e-287 ahpF O Alkyl hydroperoxide reductase
LOPFHFCG_04234 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LOPFHFCG_04235 2.3e-34 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
LOPFHFCG_04236 1.3e-128 yydK K Transcriptional regulator
LOPFHFCG_04237 7.6e-13
LOPFHFCG_04238 3.3e-119 S ABC-2 family transporter protein
LOPFHFCG_04239 1.8e-110 prrC P ABC transporter
LOPFHFCG_04240 8.4e-134 yydH O Peptidase M50
LOPFHFCG_04241 7.7e-185 S Radical SAM superfamily
LOPFHFCG_04242 8e-12
LOPFHFCG_04243 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
LOPFHFCG_04244 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
LOPFHFCG_04245 3.5e-65
LOPFHFCG_04246 7.3e-280 S Calcineurin-like phosphoesterase
LOPFHFCG_04247 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LOPFHFCG_04248 4.2e-09 S YyzF-like protein
LOPFHFCG_04249 2.2e-67
LOPFHFCG_04250 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LOPFHFCG_04252 2e-31 yycQ S Protein of unknown function (DUF2651)
LOPFHFCG_04253 1.6e-221 yycP
LOPFHFCG_04254 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LOPFHFCG_04255 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
LOPFHFCG_04256 5e-188 S aspartate phosphatase
LOPFHFCG_04258 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
LOPFHFCG_04259 9.7e-261 rocE E amino acid
LOPFHFCG_04260 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LOPFHFCG_04261 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LOPFHFCG_04262 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LOPFHFCG_04263 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LOPFHFCG_04264 7.3e-155 yycI S protein conserved in bacteria
LOPFHFCG_04265 3.1e-259 yycH S protein conserved in bacteria
LOPFHFCG_04266 0.0 vicK 2.7.13.3 T Histidine kinase
LOPFHFCG_04267 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LOPFHFCG_04272 9.6e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LOPFHFCG_04273 1.9e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOPFHFCG_04274 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LOPFHFCG_04275 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
LOPFHFCG_04277 1.9e-15 yycC K YycC-like protein
LOPFHFCG_04278 7.9e-219 yeaN P COG2807 Cyanate permease
LOPFHFCG_04279 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LOPFHFCG_04280 2.2e-73 rplI J binds to the 23S rRNA
LOPFHFCG_04281 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LOPFHFCG_04282 8.3e-160 yybS S membrane
LOPFHFCG_04284 4e-14 cotF M Spore coat protein
LOPFHFCG_04285 1.7e-51 cotF M Spore coat protein
LOPFHFCG_04286 1.7e-66 ydeP3 K Transcriptional regulator
LOPFHFCG_04287 4.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LOPFHFCG_04288 1.6e-60
LOPFHFCG_04290 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
LOPFHFCG_04291 1.1e-109 K TipAS antibiotic-recognition domain
LOPFHFCG_04292 4.8e-124
LOPFHFCG_04293 9.5e-65 yybH S SnoaL-like domain
LOPFHFCG_04294 9.6e-123 yybG S Pentapeptide repeat-containing protein
LOPFHFCG_04295 2.2e-216 ynfM EGP Major facilitator Superfamily
LOPFHFCG_04296 2.1e-165 yybE K Transcriptional regulator
LOPFHFCG_04297 2e-79 yjcF S Acetyltransferase (GNAT) domain
LOPFHFCG_04298 2.7e-77 yybC
LOPFHFCG_04299 3e-127 S Metallo-beta-lactamase superfamily
LOPFHFCG_04300 5.6e-77 yybA 2.3.1.57 K transcriptional
LOPFHFCG_04301 2.4e-72 yjcF S Acetyltransferase (GNAT) domain
LOPFHFCG_04302 7.2e-96 yyaS S Membrane
LOPFHFCG_04303 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
LOPFHFCG_04304 1.3e-65 yyaQ S YjbR
LOPFHFCG_04305 6.7e-104 yyaP 1.5.1.3 H RibD C-terminal domain
LOPFHFCG_04306 3.6e-30 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LOPFHFCG_04307 2e-82 yosT L Bacterial transcription activator, effector binding domain
LOPFHFCG_04308 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LOPFHFCG_04309 8e-168 yyaK S CAAX protease self-immunity
LOPFHFCG_04310 1.8e-243 EGP Major facilitator superfamily
LOPFHFCG_04311 1.6e-61 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LOPFHFCG_04312 1.2e-40 2.7.7.73, 2.7.7.80 H ThiF family
LOPFHFCG_04313 3.5e-34 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
LOPFHFCG_04314 1.4e-40 yxaM EGP PFAM Major Facilitator Superfamily
LOPFHFCG_04315 4.2e-61 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
LOPFHFCG_04316 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
LOPFHFCG_04317 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LOPFHFCG_04318 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LOPFHFCG_04319 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
LOPFHFCG_04320 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LOPFHFCG_04321 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LOPFHFCG_04322 2.3e-33 yyzM S protein conserved in bacteria
LOPFHFCG_04323 8.1e-177 yyaD S Membrane
LOPFHFCG_04324 1.6e-111 yyaC S Sporulation protein YyaC
LOPFHFCG_04325 2.1e-149 spo0J K Belongs to the ParB family
LOPFHFCG_04326 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
LOPFHFCG_04327 3.7e-73 S Bacterial PH domain
LOPFHFCG_04328 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LOPFHFCG_04329 4.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LOPFHFCG_04330 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LOPFHFCG_04331 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LOPFHFCG_04332 3.2e-107 jag S single-stranded nucleic acid binding R3H
LOPFHFCG_04333 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LOPFHFCG_04334 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)