ORF_ID e_value Gene_name EC_number CAZy COGs Description
LMMEADAK_00001 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LMMEADAK_00002 1.6e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LMMEADAK_00003 2.4e-33 yaaA S S4 domain
LMMEADAK_00004 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LMMEADAK_00005 8.1e-38 yaaB S Domain of unknown function (DUF370)
LMMEADAK_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LMMEADAK_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LMMEADAK_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_00011 4e-184 yaaC S YaaC-like Protein
LMMEADAK_00012 8e-274 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LMMEADAK_00013 3.6e-249 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LMMEADAK_00014 5.7e-158 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LMMEADAK_00015 6.1e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LMMEADAK_00016 2.4e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LMMEADAK_00017 7.5e-203 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LMMEADAK_00018 1.3e-09
LMMEADAK_00019 4.8e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
LMMEADAK_00020 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
LMMEADAK_00021 1.7e-211 yaaH M Glycoside Hydrolase Family
LMMEADAK_00022 9.8e-100 yaaI Q COG1335 Amidases related to nicotinamidase
LMMEADAK_00023 3.5e-85 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LMMEADAK_00024 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LMMEADAK_00025 5.9e-36 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LMMEADAK_00026 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LMMEADAK_00027 3.6e-32 yaaL S Protein of unknown function (DUF2508)
LMMEADAK_00028 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
LMMEADAK_00029 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_00032 2.2e-30 csfB S Inhibitor of sigma-G Gin
LMMEADAK_00033 1.3e-105 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
LMMEADAK_00034 1.2e-189 yaaN P Belongs to the TelA family
LMMEADAK_00035 6.2e-271 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
LMMEADAK_00036 3.4e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LMMEADAK_00037 7.5e-55 yaaQ S protein conserved in bacteria
LMMEADAK_00038 1.2e-71 yaaR S protein conserved in bacteria
LMMEADAK_00039 2.4e-181 holB 2.7.7.7 L DNA polymerase III
LMMEADAK_00040 8.8e-145 yaaT S stage 0 sporulation protein
LMMEADAK_00041 7.7e-37 yabA L Involved in initiation control of chromosome replication
LMMEADAK_00042 1.9e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
LMMEADAK_00043 3.1e-47 yazA L endonuclease containing a URI domain
LMMEADAK_00044 5.3e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LMMEADAK_00045 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
LMMEADAK_00046 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LMMEADAK_00047 5e-142 tatD L hydrolase, TatD
LMMEADAK_00048 7e-232 rpfB GH23 T protein conserved in bacteria
LMMEADAK_00049 2.1e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LMMEADAK_00050 7.4e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LMMEADAK_00051 1.4e-145 yabG S peptidase
LMMEADAK_00052 7.8e-39 veg S protein conserved in bacteria
LMMEADAK_00053 2.9e-27 sspF S DNA topological change
LMMEADAK_00054 2.1e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LMMEADAK_00055 1.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
LMMEADAK_00056 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
LMMEADAK_00057 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
LMMEADAK_00058 9.2e-248 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LMMEADAK_00059 7.2e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LMMEADAK_00060 2e-106 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LMMEADAK_00061 6.1e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LMMEADAK_00062 3.7e-40 yabK S Peptide ABC transporter permease
LMMEADAK_00063 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LMMEADAK_00064 6.2e-91 spoVT K stage V sporulation protein
LMMEADAK_00065 2e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LMMEADAK_00066 1.1e-275 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
LMMEADAK_00067 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LMMEADAK_00068 1.9e-49 yabP S Sporulation protein YabP
LMMEADAK_00069 1.7e-103 yabQ S spore cortex biosynthesis protein
LMMEADAK_00070 4.1e-57 divIC D Septum formation initiator
LMMEADAK_00071 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
LMMEADAK_00074 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
LMMEADAK_00075 1.1e-122 yabS S protein containing a von Willebrand factor type A (vWA) domain
LMMEADAK_00076 3.1e-184 KLT serine threonine protein kinase
LMMEADAK_00077 3.6e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LMMEADAK_00078 5.1e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LMMEADAK_00079 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LMMEADAK_00080 7.1e-138 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LMMEADAK_00081 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LMMEADAK_00082 5.4e-156 yacD 5.2.1.8 O peptidyl-prolyl isomerase
LMMEADAK_00083 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LMMEADAK_00084 5.8e-269 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LMMEADAK_00085 1.8e-107 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
LMMEADAK_00086 1.6e-160 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
LMMEADAK_00087 7.2e-158 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LMMEADAK_00088 2.4e-62 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LMMEADAK_00089 2.9e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LMMEADAK_00090 3.8e-28 yazB K transcriptional
LMMEADAK_00091 1.9e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LMMEADAK_00092 6.4e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LMMEADAK_00093 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_00095 1.3e-07
LMMEADAK_00098 2e-08
LMMEADAK_00103 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_00104 7.5e-77 ctsR K Belongs to the CtsR family
LMMEADAK_00105 4.1e-65 mcsA 2.7.14.1 S protein with conserved CXXC pairs
LMMEADAK_00106 4.2e-203 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
LMMEADAK_00107 0.0 clpC O Belongs to the ClpA ClpB family
LMMEADAK_00108 7e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LMMEADAK_00109 2.9e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LMMEADAK_00110 9.4e-195 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
LMMEADAK_00111 6.5e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
LMMEADAK_00112 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
LMMEADAK_00113 8.1e-279 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LMMEADAK_00114 1e-116 cysE 2.3.1.30 E Serine acetyltransferase
LMMEADAK_00115 1.4e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LMMEADAK_00116 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LMMEADAK_00117 2.8e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LMMEADAK_00118 4.2e-89 yacP S RNA-binding protein containing a PIN domain
LMMEADAK_00119 8.9e-116 sigH K Belongs to the sigma-70 factor family
LMMEADAK_00120 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
LMMEADAK_00121 3.2e-96 nusG K Participates in transcription elongation, termination and antitermination
LMMEADAK_00122 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LMMEADAK_00123 4.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LMMEADAK_00124 2.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LMMEADAK_00125 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LMMEADAK_00126 6.3e-108 rsmC 2.1.1.172 J Methyltransferase
LMMEADAK_00127 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LMMEADAK_00128 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LMMEADAK_00129 4.7e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
LMMEADAK_00130 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LMMEADAK_00131 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LMMEADAK_00132 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LMMEADAK_00133 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LMMEADAK_00134 3.4e-188 ybaC 3.4.11.5 S Alpha/beta hydrolase family
LMMEADAK_00135 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
LMMEADAK_00136 9.8e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LMMEADAK_00137 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
LMMEADAK_00138 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LMMEADAK_00139 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LMMEADAK_00140 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LMMEADAK_00141 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LMMEADAK_00142 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LMMEADAK_00143 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LMMEADAK_00144 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
LMMEADAK_00145 2.7e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LMMEADAK_00146 2.3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LMMEADAK_00147 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LMMEADAK_00148 6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LMMEADAK_00149 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LMMEADAK_00150 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LMMEADAK_00151 7.9e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LMMEADAK_00152 1.2e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LMMEADAK_00153 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LMMEADAK_00154 1.9e-23 rpmD J Ribosomal protein L30
LMMEADAK_00155 1.1e-72 rplO J binds to the 23S rRNA
LMMEADAK_00156 3.5e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LMMEADAK_00157 2.6e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LMMEADAK_00158 4.8e-142 map 3.4.11.18 E Methionine aminopeptidase
LMMEADAK_00159 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LMMEADAK_00160 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LMMEADAK_00161 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LMMEADAK_00162 1.3e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LMMEADAK_00163 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LMMEADAK_00164 4.7e-58 rplQ J Ribosomal protein L17
LMMEADAK_00165 3.9e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LMMEADAK_00166 1.6e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LMMEADAK_00167 9.1e-139 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LMMEADAK_00168 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LMMEADAK_00169 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LMMEADAK_00170 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
LMMEADAK_00171 2.4e-144 ybaJ Q Methyltransferase domain
LMMEADAK_00172 3.9e-81 yizA S Damage-inducible protein DinB
LMMEADAK_00173 1.7e-78 ybaK S Protein of unknown function (DUF2521)
LMMEADAK_00174 1.8e-133 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LMMEADAK_00175 1.9e-197 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
LMMEADAK_00176 7.6e-76 gerD
LMMEADAK_00177 6e-103 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
LMMEADAK_00178 1.4e-133 pdaB 3.5.1.104 G Polysaccharide deacetylase
LMMEADAK_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_00182 1.6e-08
LMMEADAK_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_00186 2.2e-221 glcP G Major Facilitator Superfamily
LMMEADAK_00187 1.9e-247 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LMMEADAK_00188 1.3e-179 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
LMMEADAK_00189 1.5e-202 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
LMMEADAK_00190 2.7e-226 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
LMMEADAK_00191 3.7e-174 ybaS 1.1.1.58 S Na -dependent transporter
LMMEADAK_00192 6.6e-115 ybbA S Putative esterase
LMMEADAK_00193 8e-180 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_00194 2.8e-177 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_00195 2.8e-171 feuA P Iron-uptake system-binding protein
LMMEADAK_00196 0.0 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
LMMEADAK_00197 3.9e-237 ybbC 3.2.1.52 S protein conserved in bacteria
LMMEADAK_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
LMMEADAK_00199 5.2e-245 yfeW 3.4.16.4 V Belongs to the UPF0214 family
LMMEADAK_00200 4.4e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LMMEADAK_00201 4.4e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LMMEADAK_00202 2.6e-85 ybbJ J acetyltransferase
LMMEADAK_00203 3e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
LMMEADAK_00209 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
LMMEADAK_00210 5.9e-117 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
LMMEADAK_00211 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LMMEADAK_00212 6.3e-223 ybbR S protein conserved in bacteria
LMMEADAK_00213 4.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LMMEADAK_00214 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LMMEADAK_00215 1.1e-158
LMMEADAK_00216 5.6e-63 S Bacteriophage abortive infection AbiH
LMMEADAK_00217 4.1e-59
LMMEADAK_00218 2.4e-156 V ATPases associated with a variety of cellular activities
LMMEADAK_00219 4.1e-105 S ABC-2 family transporter protein
LMMEADAK_00220 2.5e-100 ybdN
LMMEADAK_00221 2.1e-131 ybdO S Domain of unknown function (DUF4885)
LMMEADAK_00222 1.9e-163 dkgB S Aldo/keto reductase family
LMMEADAK_00223 1e-93 yxaC M effector of murein hydrolase
LMMEADAK_00224 6.9e-52 S LrgA family
LMMEADAK_00225 4e-72 yxaD K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_00226 8.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
LMMEADAK_00227 3.3e-92 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
LMMEADAK_00228 4e-103 T Histidine kinase
LMMEADAK_00229 1.1e-81 KT helix_turn_helix, Lux Regulon
LMMEADAK_00230 3.5e-134 V ABC transporter, ATP-binding protein
LMMEADAK_00231 2.3e-146 V ABC-2 type transporter
LMMEADAK_00232 4.6e-123 V ABC-2 type transporter
LMMEADAK_00233 4.4e-14
LMMEADAK_00234 6.2e-59 bacT Q Thioesterase domain
LMMEADAK_00235 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
LMMEADAK_00236 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
LMMEADAK_00237 1.8e-120 fabD 2.3.1.39 I PFAM Acyl transferase
LMMEADAK_00238 0.0 Q Beta-ketoacyl synthase
LMMEADAK_00239 0.0 Q Polyketide synthase modules and related proteins
LMMEADAK_00240 1.5e-102 Q Flavin containing amine oxidoreductase
LMMEADAK_00241 0.0 Q TIGRFAM amino acid adenylation domain
LMMEADAK_00242 4.6e-50 crtF 2.1.1.210 Q PFAM O-methyltransferase
LMMEADAK_00243 4.5e-77 S Domain of unknown function (DUF4879)
LMMEADAK_00244 5.8e-39 csgA S Sigma-G-dependent sporulation-specific SASP protein
LMMEADAK_00245 1.6e-110 yqeB
LMMEADAK_00246 4.6e-39 ybyB
LMMEADAK_00247 2.5e-292 ybeC E amino acid
LMMEADAK_00248 7.1e-15 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LMMEADAK_00249 1.9e-55
LMMEADAK_00250 2.6e-15 S Protein of unknown function (DUF2651)
LMMEADAK_00251 2.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LMMEADAK_00252 1.7e-259 glpT G -transporter
LMMEADAK_00253 1.3e-16 S Protein of unknown function (DUF2651)
LMMEADAK_00254 5e-212 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
LMMEADAK_00256 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
LMMEADAK_00257 7.8e-31
LMMEADAK_00258 1.2e-82 K Helix-turn-helix XRE-family like proteins
LMMEADAK_00259 6.7e-81 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LMMEADAK_00260 1.7e-105 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LMMEADAK_00261 6.2e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LMMEADAK_00262 5e-93 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LMMEADAK_00263 1.9e-86 ybfM S SNARE associated Golgi protein
LMMEADAK_00264 7.3e-152 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
LMMEADAK_00265 2.1e-42 ybfN
LMMEADAK_00266 2.3e-192 yceA S Belongs to the UPF0176 family
LMMEADAK_00267 1.9e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LMMEADAK_00268 5.5e-200 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LMMEADAK_00269 1.4e-257 mmuP E amino acid
LMMEADAK_00270 1.2e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
LMMEADAK_00271 9.3e-259 agcS E Sodium alanine symporter
LMMEADAK_00272 1.4e-189 glsA 3.5.1.2 E Belongs to the glutaminase family
LMMEADAK_00273 1.5e-212 phoQ 2.7.13.3 T Histidine kinase
LMMEADAK_00274 6.3e-171 glnL T Regulator
LMMEADAK_00275 5.2e-37 ycbJ S Macrolide 2'-phosphotransferase
LMMEADAK_00276 8.2e-26 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
LMMEADAK_00277 1.8e-156 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LMMEADAK_00278 2.5e-112 ydfN C nitroreductase
LMMEADAK_00279 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
LMMEADAK_00280 1.5e-62 mhqP S DoxX
LMMEADAK_00281 1.6e-55 traF CO Thioredoxin
LMMEADAK_00282 5.6e-62 ycbP S Protein of unknown function (DUF2512)
LMMEADAK_00283 5.3e-77 sleB 3.5.1.28 M Cell wall
LMMEADAK_00284 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
LMMEADAK_00285 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LMMEADAK_00286 5.2e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LMMEADAK_00287 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
LMMEADAK_00288 1.8e-209 ycbU E Selenocysteine lyase
LMMEADAK_00289 1.1e-238 lmrB EGP the major facilitator superfamily
LMMEADAK_00290 2.7e-100 yxaF K Transcriptional regulator
LMMEADAK_00291 5.8e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LMMEADAK_00292 5.7e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
LMMEADAK_00293 1.3e-196 yccF K DNA-templated transcriptional preinitiation complex assembly
LMMEADAK_00294 6.2e-171 yccK C Aldo keto reductase
LMMEADAK_00295 2.1e-177 ycdA S Domain of unknown function (DUF5105)
LMMEADAK_00296 4.8e-260 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
LMMEADAK_00297 1.3e-267 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
LMMEADAK_00298 6.2e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
LMMEADAK_00299 9.3e-190 S response regulator aspartate phosphatase
LMMEADAK_00300 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
LMMEADAK_00301 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
LMMEADAK_00302 3.9e-163 adcA P Belongs to the bacterial solute-binding protein 9 family
LMMEADAK_00303 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
LMMEADAK_00304 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
LMMEADAK_00305 4.7e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LMMEADAK_00306 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
LMMEADAK_00307 3.7e-105 yceD T proteins involved in stress response, homologs of TerZ and
LMMEADAK_00308 1e-107 yceE T proteins involved in stress response, homologs of TerZ and
LMMEADAK_00309 9.7e-138 terC P Protein of unknown function (DUF475)
LMMEADAK_00310 0.0 yceG S Putative component of 'biosynthetic module'
LMMEADAK_00311 2.3e-193 yceH P Belongs to the TelA family
LMMEADAK_00312 2.1e-216 naiP P Uncharacterised MFS-type transporter YbfB
LMMEADAK_00313 3.9e-229 proV 3.6.3.32 E glycine betaine
LMMEADAK_00314 1.6e-138 opuAB P glycine betaine
LMMEADAK_00315 3.1e-164 opuAC E glycine betaine
LMMEADAK_00316 1.1e-211 amhX S amidohydrolase
LMMEADAK_00317 2.4e-230 ycgA S Membrane
LMMEADAK_00318 6.3e-82 ycgB
LMMEADAK_00319 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
LMMEADAK_00320 5.7e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LMMEADAK_00321 8.1e-261 mdr EGP Major facilitator Superfamily
LMMEADAK_00322 1.8e-75 emrR K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_00323 4.7e-114 ycgF E Lysine exporter protein LysE YggA
LMMEADAK_00324 9.9e-151 yqcI S YqcI/YcgG family
LMMEADAK_00325 1.9e-245 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
LMMEADAK_00326 7.6e-114 ycgI S Domain of unknown function (DUF1989)
LMMEADAK_00327 3.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LMMEADAK_00329 2.2e-137 4.2.1.118 G Xylose isomerase-like TIM barrel
LMMEADAK_00330 6.1e-233 G COG0477 Permeases of the major facilitator superfamily
LMMEADAK_00331 8.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LMMEADAK_00332 1.3e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
LMMEADAK_00333 3.6e-148 ycgL S Predicted nucleotidyltransferase
LMMEADAK_00334 2.3e-170 ycgM E Proline dehydrogenase
LMMEADAK_00335 1.1e-292 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LMMEADAK_00336 6.4e-244 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LMMEADAK_00337 2.8e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
LMMEADAK_00338 6.4e-190 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LMMEADAK_00339 2.5e-280 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LMMEADAK_00340 3.5e-57 nirD 1.7.1.15 P Nitrite reductase
LMMEADAK_00341 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LMMEADAK_00342 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LMMEADAK_00343 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
LMMEADAK_00344 2.4e-223 nasA P COG2223 Nitrate nitrite transporter
LMMEADAK_00345 7.8e-227 yciC S GTPases (G3E family)
LMMEADAK_00346 4.6e-221 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LMMEADAK_00347 4.7e-73 yckC S membrane
LMMEADAK_00348 2.2e-51 S Protein of unknown function (DUF2680)
LMMEADAK_00349 1.1e-296 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LMMEADAK_00350 2.1e-67 nin S Competence protein J (ComJ)
LMMEADAK_00351 2.4e-77 nucA M Deoxyribonuclease NucA/NucB
LMMEADAK_00352 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
LMMEADAK_00353 1.1e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
LMMEADAK_00354 2.8e-63 hxlR K transcriptional
LMMEADAK_00355 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_00356 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_00357 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
LMMEADAK_00358 1.3e-139 srfAD Q thioesterase
LMMEADAK_00359 3.9e-248 bamJ E Aminotransferase class I and II
LMMEADAK_00360 4.8e-64 S YcxB-like protein
LMMEADAK_00362 6e-169 ycxC EG EamA-like transporter family
LMMEADAK_00363 1.3e-246 ycxD K GntR family transcriptional regulator
LMMEADAK_00364 4.5e-131 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
LMMEADAK_00365 4.1e-110 yczE S membrane
LMMEADAK_00366 1.1e-133 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LMMEADAK_00367 2.1e-118 tcyB P COG0765 ABC-type amino acid transport system, permease component
LMMEADAK_00368 1.4e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
LMMEADAK_00369 9.6e-158 bsdA K LysR substrate binding domain
LMMEADAK_00370 6e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
LMMEADAK_00371 5.3e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
LMMEADAK_00372 2e-38 bsdD 4.1.1.61 S response to toxic substance
LMMEADAK_00373 1.3e-76 yclD
LMMEADAK_00374 4.1e-270 dtpT E amino acid peptide transporter
LMMEADAK_00375 6.3e-281 yclG M Pectate lyase superfamily protein
LMMEADAK_00377 4.5e-294 gerKA EG Spore germination protein
LMMEADAK_00378 6.5e-237 gerKC S spore germination
LMMEADAK_00379 1.9e-195 gerKB F Spore germination protein
LMMEADAK_00380 3.4e-255 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LMMEADAK_00381 1.8e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LMMEADAK_00382 4.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
LMMEADAK_00383 3.5e-115 yxeN P COG0765 ABC-type amino acid transport system, permease component
LMMEADAK_00384 3.5e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
LMMEADAK_00385 4.9e-218 yxeP 3.5.1.47 E hydrolase activity
LMMEADAK_00386 1.3e-254 yxeQ S MmgE/PrpD family
LMMEADAK_00387 3.9e-122 yclH P ABC transporter
LMMEADAK_00388 6.2e-223 yclI V ABC transporter (permease) YclI
LMMEADAK_00389 2e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_00390 2e-261 T PhoQ Sensor
LMMEADAK_00391 1.9e-81 S aspartate phosphatase
LMMEADAK_00393 1.9e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
LMMEADAK_00394 3e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_00395 1e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_00396 6.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
LMMEADAK_00397 3.2e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
LMMEADAK_00398 1.7e-249 ycnB EGP Major facilitator Superfamily
LMMEADAK_00399 1.2e-152 ycnC K Transcriptional regulator
LMMEADAK_00400 2.3e-136 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
LMMEADAK_00401 1e-44 ycnE S Monooxygenase
LMMEADAK_00402 1.5e-52 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
LMMEADAK_00403 1.4e-262 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LMMEADAK_00404 5.3e-221 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LMMEADAK_00405 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LMMEADAK_00406 3.6e-149 glcU U Glucose uptake
LMMEADAK_00407 1.1e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_00408 3.3e-96 ycnI S protein conserved in bacteria
LMMEADAK_00409 9.4e-300 ycnJ P protein, homolog of Cu resistance protein CopC
LMMEADAK_00410 1.9e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
LMMEADAK_00411 6e-55
LMMEADAK_00412 2.7e-226 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
LMMEADAK_00413 1.4e-72 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
LMMEADAK_00414 1.9e-206 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
LMMEADAK_00415 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
LMMEADAK_00417 2.3e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LMMEADAK_00418 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
LMMEADAK_00419 3.7e-208 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
LMMEADAK_00420 2.3e-150 ycsI S Belongs to the D-glutamate cyclase family
LMMEADAK_00421 5.4e-138 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
LMMEADAK_00422 2.9e-190 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
LMMEADAK_00423 2e-130 kipR K Transcriptional regulator
LMMEADAK_00424 8.4e-119 ycsK E anatomical structure formation involved in morphogenesis
LMMEADAK_00426 5.1e-56 yczJ S biosynthesis
LMMEADAK_00427 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
LMMEADAK_00428 1.5e-174 ydhF S Oxidoreductase
LMMEADAK_00429 0.0 mtlR K transcriptional regulator, MtlR
LMMEADAK_00430 2e-288 ydaB IQ acyl-CoA ligase
LMMEADAK_00431 3.7e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_00432 1.5e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
LMMEADAK_00433 3.6e-114 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LMMEADAK_00434 4e-77 ydaG 1.4.3.5 S general stress protein
LMMEADAK_00435 5.4e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
LMMEADAK_00436 1.2e-44 L COG2963 Transposase and inactivated derivatives
LMMEADAK_00437 1e-137 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_00438 1.3e-47 ydzA EGP Major facilitator Superfamily
LMMEADAK_00439 4.3e-74 lrpC K Transcriptional regulator
LMMEADAK_00440 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LMMEADAK_00441 6.7e-201 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
LMMEADAK_00442 7.9e-149 ydaK T Diguanylate cyclase, GGDEF domain
LMMEADAK_00443 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
LMMEADAK_00444 5.5e-231 ydaM M Glycosyl transferase family group 2
LMMEADAK_00445 0.0 ydaN S Bacterial cellulose synthase subunit
LMMEADAK_00447 0.0 ydaO E amino acid
LMMEADAK_00448 8.5e-78 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LMMEADAK_00449 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
LMMEADAK_00450 3.1e-58 K acetyltransferase
LMMEADAK_00451 1.7e-34
LMMEADAK_00453 8.4e-39 yqbQ 3.2.1.96 G NLP P60 protein
LMMEADAK_00454 5.9e-34 xkdR S Protein of unknown function (DUF2577)
LMMEADAK_00455 7.3e-108 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LMMEADAK_00456 3.7e-15 xkdS S Protein of unknown function (DUF2634)
LMMEADAK_00457 6.2e-21 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LMMEADAK_00459 1.3e-78
LMMEADAK_00460 1.3e-99
LMMEADAK_00461 4.7e-39
LMMEADAK_00462 3.2e-226 mntH P H( )-stimulated, divalent metal cation uptake system
LMMEADAK_00464 6.5e-34 ydaT
LMMEADAK_00465 2.2e-72 yvaD S Family of unknown function (DUF5360)
LMMEADAK_00466 4.1e-54 yvaE P Small Multidrug Resistance protein
LMMEADAK_00467 4.4e-141 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
LMMEADAK_00469 1.7e-57 ydbB G Cupin domain
LMMEADAK_00470 1.1e-62 ydbC S Domain of unknown function (DUF4937
LMMEADAK_00471 2.7e-154 ydbD P Catalase
LMMEADAK_00472 1.9e-200 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
LMMEADAK_00473 2.1e-299 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LMMEADAK_00474 3.9e-119 dctR T COG4565 Response regulator of citrate malate metabolism
LMMEADAK_00475 1.7e-224 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LMMEADAK_00476 3.2e-160 ydbI S AI-2E family transporter
LMMEADAK_00477 5e-173 ydbJ V ABC transporter, ATP-binding protein
LMMEADAK_00478 7.4e-130 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LMMEADAK_00479 2.1e-52 ydbL
LMMEADAK_00480 9.2e-206 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
LMMEADAK_00481 1.5e-10 S Fur-regulated basic protein B
LMMEADAK_00482 4.4e-09 S Fur-regulated basic protein A
LMMEADAK_00483 2.4e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LMMEADAK_00484 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LMMEADAK_00485 3.2e-203 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LMMEADAK_00486 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
LMMEADAK_00487 1.3e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
LMMEADAK_00488 1.3e-60 ydbS S Bacterial PH domain
LMMEADAK_00489 1.1e-262 ydbT S Membrane
LMMEADAK_00490 1.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
LMMEADAK_00491 6.2e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LMMEADAK_00492 7.6e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
LMMEADAK_00493 1.7e-218 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LMMEADAK_00494 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
LMMEADAK_00495 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
LMMEADAK_00496 6.1e-146 rsbR T Positive regulator of sigma-B
LMMEADAK_00497 6.8e-57 rsbS T antagonist
LMMEADAK_00498 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
LMMEADAK_00499 4.6e-188 rsbU 3.1.3.3 KT phosphatase
LMMEADAK_00500 1.4e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
LMMEADAK_00501 2.1e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
LMMEADAK_00502 1.4e-139 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LMMEADAK_00503 9.7e-109 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
LMMEADAK_00504 0.0 yhgF K COG2183 Transcriptional accessory protein
LMMEADAK_00505 1.7e-14
LMMEADAK_00506 1.9e-58 ydcK S Belongs to the SprT family
LMMEADAK_00514 1.1e-08
LMMEADAK_00515 1.3e-28 S Doxx family
LMMEADAK_00516 3.3e-78 K Transcriptional regulator
LMMEADAK_00517 2.4e-97 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LMMEADAK_00518 7.3e-102 GM NAD(P)H-binding
LMMEADAK_00519 2.6e-56 azoR I NADPH-dependent FMN reductase
LMMEADAK_00520 4.3e-45 K Acetyltransferase (GNAT) domain
LMMEADAK_00521 2.9e-35 S response regulator aspartate phosphatase
LMMEADAK_00522 5.3e-95 ywrO S Flavodoxin-like fold
LMMEADAK_00523 1.2e-231 proP EGP Transporter
LMMEADAK_00524 5e-48 ohrR K Transcriptional regulator
LMMEADAK_00525 1.2e-85 S Domain of unknown function with cystatin-like fold (DUF4467)
LMMEADAK_00526 1.4e-74 maoC I N-terminal half of MaoC dehydratase
LMMEADAK_00527 5.2e-62 yyaQ S YjbR
LMMEADAK_00528 5.1e-75 ywnA K Transcriptional regulator
LMMEADAK_00529 4.9e-111 ywnB S NAD(P)H-binding
LMMEADAK_00530 6.3e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LMMEADAK_00531 5.2e-30 cspL K Cold shock
LMMEADAK_00532 6.8e-78 carD K Transcription factor
LMMEADAK_00533 4.8e-120 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
LMMEADAK_00534 1e-104 S Protein of unknown function (DUF2812)
LMMEADAK_00535 1.3e-51 K Transcriptional regulator PadR-like family
LMMEADAK_00536 1.4e-181 S Patatin-like phospholipase
LMMEADAK_00537 1.9e-83 S DinB superfamily
LMMEADAK_00538 6.7e-60 G Cupin domain
LMMEADAK_00539 1.4e-167 czcD P COG1230 Co Zn Cd efflux system component
LMMEADAK_00540 1.3e-198 trkA P Oxidoreductase
LMMEADAK_00542 1.1e-149 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
LMMEADAK_00544 7.1e-200 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
LMMEADAK_00545 1.7e-55 ydeH
LMMEADAK_00546 3.7e-84 F nucleoside 2-deoxyribosyltransferase
LMMEADAK_00547 7.3e-194 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LMMEADAK_00548 1.2e-148 Q ubiE/COQ5 methyltransferase family
LMMEADAK_00549 3.8e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LMMEADAK_00550 1.8e-234 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LMMEADAK_00551 2e-164 S Sodium Bile acid symporter family
LMMEADAK_00552 1.2e-202 adhA 1.1.1.1 C alcohol dehydrogenase
LMMEADAK_00553 3.6e-67 yraB K helix_turn_helix, mercury resistance
LMMEADAK_00554 2.9e-227 mleN_2 C antiporter
LMMEADAK_00555 5.1e-262 K helix_turn_helix gluconate operon transcriptional repressor
LMMEADAK_00556 1.8e-113 paiB K Transcriptional regulator
LMMEADAK_00558 4.2e-180 ydeR EGP Major facilitator Superfamily
LMMEADAK_00559 4.5e-103 ydeS K Transcriptional regulator
LMMEADAK_00560 6.3e-157 ydeK EG -transporter
LMMEADAK_00561 3.2e-264 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LMMEADAK_00562 9.5e-49 yraD M Spore coat protein
LMMEADAK_00563 4.9e-25 yraE
LMMEADAK_00564 4.2e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
LMMEADAK_00565 8.4e-63 yraF M Spore coat protein
LMMEADAK_00566 2.6e-36 yraG
LMMEADAK_00567 3.2e-218 ydfH 2.7.13.3 T Histidine kinase
LMMEADAK_00568 2.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LMMEADAK_00569 0.0 ydfJ S drug exporters of the RND superfamily
LMMEADAK_00570 1.6e-134 puuD S Peptidase C26
LMMEADAK_00571 6.7e-298 expZ S ABC transporter
LMMEADAK_00572 6.1e-99 ynaD J Acetyltransferase (GNAT) domain
LMMEADAK_00573 7.2e-150 S Uncharacterized protein conserved in bacteria (DUF2179)
LMMEADAK_00574 3.6e-197 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
LMMEADAK_00575 2e-209 tcaB EGP Major facilitator Superfamily
LMMEADAK_00576 6.8e-226 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LMMEADAK_00577 5e-156 K Helix-turn-helix XRE-family like proteins
LMMEADAK_00578 2.2e-123 ydhB S membrane transporter protein
LMMEADAK_00579 2.2e-81 bltD 2.3.1.57 K FR47-like protein
LMMEADAK_00580 2.4e-150 bltR K helix_turn_helix, mercury resistance
LMMEADAK_00581 1.6e-27 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LMMEADAK_00582 7.2e-110 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LMMEADAK_00583 1.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
LMMEADAK_00584 7.5e-146 ycgJ_1 Q ubiE/COQ5 methyltransferase family
LMMEADAK_00585 4e-166 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
LMMEADAK_00586 3.1e-119 ydhC K FCD
LMMEADAK_00587 3.7e-229 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LMMEADAK_00590 3.1e-264 pbpE V Beta-lactamase
LMMEADAK_00592 6.1e-97 ydhK M Protein of unknown function (DUF1541)
LMMEADAK_00593 1.2e-195 pbuE EGP Major facilitator Superfamily
LMMEADAK_00594 1.3e-133 ydhQ K UTRA
LMMEADAK_00595 2.6e-118 K FCD
LMMEADAK_00596 7.4e-217 yeaN P COG2807 Cyanate permease
LMMEADAK_00597 7.7e-49 sugE P Small Multidrug Resistance protein
LMMEADAK_00598 2.3e-51 ykkC P Small Multidrug Resistance protein
LMMEADAK_00599 5.3e-104 yvdT K Transcriptional regulator
LMMEADAK_00600 1.2e-296 yveA E amino acid
LMMEADAK_00601 8.7e-164 ydhU P Catalase
LMMEADAK_00602 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
LMMEADAK_00603 4.7e-185 yhfP 1.1.1.1 C Quinone oxidoreductase
LMMEADAK_00604 3.2e-251 iolT EGP Major facilitator Superfamily
LMMEADAK_00607 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_00608 7.8e-08
LMMEADAK_00610 8.7e-184 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LMMEADAK_00611 4.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
LMMEADAK_00612 1.3e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
LMMEADAK_00613 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LMMEADAK_00614 1.7e-190 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LMMEADAK_00615 0.0 ydiF S ABC transporter
LMMEADAK_00616 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
LMMEADAK_00617 3e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LMMEADAK_00618 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
LMMEADAK_00619 2.7e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LMMEADAK_00620 1.7e-27 ydiK S Domain of unknown function (DUF4305)
LMMEADAK_00621 4.3e-127 ydiL S CAAX protease self-immunity
LMMEADAK_00622 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LMMEADAK_00623 7.5e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LMMEADAK_00624 1.5e-24 S Protein of unknown function (DUF4064)
LMMEADAK_00625 0.0 K NB-ARC domain
LMMEADAK_00626 8e-199 gutB 1.1.1.14 E Dehydrogenase
LMMEADAK_00627 4.4e-250 gutA G MFS/sugar transport protein
LMMEADAK_00628 5.8e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
LMMEADAK_00629 8.1e-30 yjdJ S Domain of unknown function (DUF4306)
LMMEADAK_00630 3.9e-114 pspA KT Phage shock protein A
LMMEADAK_00631 4.7e-180 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LMMEADAK_00632 1.4e-120 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
LMMEADAK_00633 7.6e-151 ydjI S virion core protein (lumpy skin disease virus)
LMMEADAK_00634 0.0 yrhL I Acyltransferase family
LMMEADAK_00635 6.8e-108 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_00636 1.2e-44 L COG2963 Transposase and inactivated derivatives
LMMEADAK_00637 2.3e-143 rsiV S Protein of unknown function (DUF3298)
LMMEADAK_00638 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LMMEADAK_00639 8.9e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
LMMEADAK_00640 1.4e-62 ydjM M Lytic transglycolase
LMMEADAK_00641 4.9e-132 ydjN U Involved in the tonB-independent uptake of proteins
LMMEADAK_00643 7.2e-35 ydjO S Cold-inducible protein YdjO
LMMEADAK_00644 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
LMMEADAK_00645 5.6e-245 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
LMMEADAK_00646 2.2e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LMMEADAK_00647 1.3e-176 yeaC S COG0714 MoxR-like ATPases
LMMEADAK_00648 3e-215 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
LMMEADAK_00649 0.0 yebA E COG1305 Transglutaminase-like enzymes
LMMEADAK_00650 2.2e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LMMEADAK_00651 1.7e-93 sigV K Belongs to the sigma-70 factor family. ECF subfamily
LMMEADAK_00652 1.2e-258 S Domain of unknown function (DUF4179)
LMMEADAK_00653 6.2e-209 pbuG S permease
LMMEADAK_00654 3.9e-134 yebC M Membrane
LMMEADAK_00656 2e-92 yebE S UPF0316 protein
LMMEADAK_00657 5.5e-29 yebG S NETI protein
LMMEADAK_00658 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LMMEADAK_00659 3.6e-224 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LMMEADAK_00660 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LMMEADAK_00661 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LMMEADAK_00662 4.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LMMEADAK_00663 2.3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LMMEADAK_00664 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LMMEADAK_00665 8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LMMEADAK_00666 2.7e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LMMEADAK_00667 2.2e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LMMEADAK_00668 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LMMEADAK_00669 2.4e-234 purD 6.3.4.13 F Belongs to the GARS family
LMMEADAK_00670 1.2e-25 S Protein of unknown function (DUF2892)
LMMEADAK_00671 0.0 yerA 3.5.4.2 F adenine deaminase
LMMEADAK_00672 1.4e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
LMMEADAK_00673 2.4e-50 yerC S protein conserved in bacteria
LMMEADAK_00674 6.7e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
LMMEADAK_00675 2.4e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
LMMEADAK_00676 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LMMEADAK_00677 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LMMEADAK_00678 2.3e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
LMMEADAK_00679 5.5e-194 yerI S homoserine kinase type II (protein kinase fold)
LMMEADAK_00680 4.3e-121 sapB S MgtC SapB transporter
LMMEADAK_00681 4.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LMMEADAK_00682 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LMMEADAK_00683 2.3e-273 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LMMEADAK_00684 5.2e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LMMEADAK_00685 9.6e-155 yerO K Transcriptional regulator
LMMEADAK_00686 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LMMEADAK_00687 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LMMEADAK_00688 3.2e-248 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LMMEADAK_00689 4.5e-21
LMMEADAK_00690 1.6e-158 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
LMMEADAK_00691 5e-138 cylB V ABC-2 type transporter
LMMEADAK_00692 3.2e-59 S Protein of unknown function, DUF600
LMMEADAK_00693 2.3e-49 S Protein of unknown function, DUF600
LMMEADAK_00694 4.2e-51 S Protein of unknown function, DUF600
LMMEADAK_00695 0.0 yobL L nucleic acid phosphodiester bond hydrolysis
LMMEADAK_00696 9.6e-17
LMMEADAK_00697 7.1e-259 yobL S Bacterial EndoU nuclease
LMMEADAK_00698 9.4e-127 yeeN K transcriptional regulatory protein
LMMEADAK_00700 4.1e-45 cotJA S Spore coat associated protein JA (CotJA)
LMMEADAK_00701 1.3e-44 cotJB S CotJB protein
LMMEADAK_00702 8.9e-104 cotJC P Spore Coat
LMMEADAK_00703 9.8e-97 yesJ K Acetyltransferase (GNAT) family
LMMEADAK_00705 1.1e-119 yetF S membrane
LMMEADAK_00706 5.7e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
LMMEADAK_00707 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LMMEADAK_00708 2.6e-155 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LMMEADAK_00709 1.2e-22 yezD S Uncharacterized small protein (DUF2292)
LMMEADAK_00710 5.8e-54 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
LMMEADAK_00711 1.1e-105 yetJ S Belongs to the BI1 family
LMMEADAK_00714 1.9e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_00715 9.3e-206 yetM CH FAD binding domain
LMMEADAK_00716 7.5e-197 yetN S Protein of unknown function (DUF3900)
LMMEADAK_00717 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LMMEADAK_00719 1.2e-49 MA20_23570 K Winged helix DNA-binding domain
LMMEADAK_00720 3.7e-165 V ATPases associated with a variety of cellular activities
LMMEADAK_00721 3.7e-126 V ABC-2 type transporter
LMMEADAK_00722 6.4e-75 S protein homooligomerization
LMMEADAK_00723 9.2e-127
LMMEADAK_00724 1.3e-190 S ATP diphosphatase activity
LMMEADAK_00725 7.3e-266 S YcaO cyclodehydratase, ATP-ad Mg2+-binding
LMMEADAK_00726 3.3e-152 sagB C Nitroreductase family
LMMEADAK_00727 1.4e-111 S CAAX protease self-immunity
LMMEADAK_00728 5e-145 2.1.1.163, 2.1.1.201 Q methyltransferase
LMMEADAK_00730 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LMMEADAK_00731 7.9e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
LMMEADAK_00732 2.4e-172 yfnG 4.2.1.45 M dehydratase
LMMEADAK_00733 1.6e-179 yfnF M Nucleotide-diphospho-sugar transferase
LMMEADAK_00734 8.6e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
LMMEADAK_00735 4.7e-187 yfnD M Nucleotide-diphospho-sugar transferase
LMMEADAK_00736 3.6e-219 fsr P COG0477 Permeases of the major facilitator superfamily
LMMEADAK_00737 7.8e-247 yfnA E amino acid
LMMEADAK_00738 5.9e-277 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LMMEADAK_00739 9.8e-115 yfmS NT chemotaxis protein
LMMEADAK_00740 1.5e-166 IQ Enoyl-(Acyl carrier protein) reductase
LMMEADAK_00741 6.5e-209 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LMMEADAK_00742 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LMMEADAK_00743 6.2e-70 yfmP K transcriptional
LMMEADAK_00744 2.1e-208 yfmO EGP Major facilitator Superfamily
LMMEADAK_00745 5.4e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LMMEADAK_00746 1.4e-206 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
LMMEADAK_00747 2.4e-64 yfmK 2.3.1.128 K acetyltransferase
LMMEADAK_00748 1.4e-189 yfmJ S N-terminal domain of oxidoreductase
LMMEADAK_00749 1.7e-24 S Protein of unknown function (DUF3212)
LMMEADAK_00750 1.3e-57 yflT S Heat induced stress protein YflT
LMMEADAK_00751 2.4e-242 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
LMMEADAK_00752 3.5e-234 yflS P Sodium:sulfate symporter transmembrane region
LMMEADAK_00753 1e-27 Q PFAM Collagen triple helix
LMMEADAK_00754 3e-38 Q Collagen triple helix repeat (20 copies)
LMMEADAK_00755 0.0 ywpD T PhoQ Sensor
LMMEADAK_00756 1.6e-151 M1-574 T Transcriptional regulatory protein, C terminal
LMMEADAK_00757 0.0 M1-568 M cell wall anchor domain
LMMEADAK_00758 2.7e-80 srtA 3.4.22.70 M Sortase family
LMMEADAK_00759 2.5e-273 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LMMEADAK_00760 4.7e-120 citT T response regulator
LMMEADAK_00761 8.3e-179 yflP S Tripartite tricarboxylate transporter family receptor
LMMEADAK_00762 3.8e-227 citM C Citrate transporter
LMMEADAK_00763 4.3e-149 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
LMMEADAK_00764 7.1e-219 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
LMMEADAK_00765 7.6e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LMMEADAK_00766 4.4e-123 yflK S protein conserved in bacteria
LMMEADAK_00767 7.7e-14 yflJ S Protein of unknown function (DUF2639)
LMMEADAK_00768 7e-19 yflI
LMMEADAK_00769 2e-49 yflH S Protein of unknown function (DUF3243)
LMMEADAK_00770 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
LMMEADAK_00771 8.7e-246 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
LMMEADAK_00772 6.3e-73 yfmQ S Uncharacterised protein from bacillus cereus group
LMMEADAK_00773 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LMMEADAK_00774 7.8e-64 yhdN S Domain of unknown function (DUF1992)
LMMEADAK_00775 2e-79 cotP O Belongs to the small heat shock protein (HSP20) family
LMMEADAK_00776 3.6e-38 ydgA S Spore germination protein gerPA/gerPF
LMMEADAK_00777 1.5e-37 ydgB S Spore germination protein gerPA/gerPF
LMMEADAK_00778 1.5e-240 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LMMEADAK_00779 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LMMEADAK_00780 1.7e-128 treR K transcriptional
LMMEADAK_00781 1.2e-123 yfkO C nitroreductase
LMMEADAK_00782 1.2e-124 yibF S YibE/F-like protein
LMMEADAK_00783 4.1e-201 yibE S YibE/F-like protein
LMMEADAK_00785 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
LMMEADAK_00786 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
LMMEADAK_00787 1.2e-186 K helix_turn _helix lactose operon repressor
LMMEADAK_00788 1.1e-164 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LMMEADAK_00789 1.2e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LMMEADAK_00790 3.6e-192 ydiM EGP Major facilitator Superfamily
LMMEADAK_00791 2.7e-29 yfkK S Belongs to the UPF0435 family
LMMEADAK_00792 1.4e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LMMEADAK_00793 8.5e-51 yfkI S gas vesicle protein
LMMEADAK_00794 6.8e-145 yihY S Belongs to the UPF0761 family
LMMEADAK_00796 2.9e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
LMMEADAK_00797 3.2e-184 cax P COG0387 Ca2 H antiporter
LMMEADAK_00798 2.5e-144 yfkD S YfkD-like protein
LMMEADAK_00799 7.3e-147 yfkC M Mechanosensitive ion channel
LMMEADAK_00800 1.5e-219 yfkA S YfkB-like domain
LMMEADAK_00801 4.9e-27 yfjT
LMMEADAK_00802 9e-155 pdaA G deacetylase
LMMEADAK_00803 1.5e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
LMMEADAK_00804 9.3e-33
LMMEADAK_00805 1.5e-183 corA P Mediates influx of magnesium ions
LMMEADAK_00806 5.7e-163 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LMMEADAK_00807 4.8e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LMMEADAK_00808 7.8e-51 S YfzA-like protein
LMMEADAK_00809 2.7e-193 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LMMEADAK_00810 2.1e-86 yfjM S Psort location Cytoplasmic, score
LMMEADAK_00811 7.5e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LMMEADAK_00812 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LMMEADAK_00813 2e-214 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LMMEADAK_00814 3.5e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LMMEADAK_00815 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
LMMEADAK_00816 4.2e-15 sspH S Belongs to the SspH family
LMMEADAK_00817 3.4e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LMMEADAK_00818 1.7e-139 glvR F Helix-turn-helix domain, rpiR family
LMMEADAK_00819 8.3e-293 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LMMEADAK_00820 2.4e-311 yfiB3 V ABC transporter
LMMEADAK_00821 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
LMMEADAK_00822 7e-63 mhqP S DoxX
LMMEADAK_00823 4.1e-161 yfiE 1.13.11.2 S glyoxalase
LMMEADAK_00824 3.1e-170 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LMMEADAK_00825 1.7e-96 padR K transcriptional
LMMEADAK_00826 1.9e-112 1.6.5.2 S NADPH-dependent FMN reductase
LMMEADAK_00827 5.3e-182 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
LMMEADAK_00828 0.0 2.7.9.2 GT phosphoenolpyruvate synthase
LMMEADAK_00829 1.5e-45 yrdF K ribonuclease inhibitor
LMMEADAK_00830 1.6e-99 yfiT S Belongs to the metal hydrolase YfiT family
LMMEADAK_00831 2.5e-289 yfiU EGP Major facilitator Superfamily
LMMEADAK_00832 5.6e-83 yfiV K transcriptional
LMMEADAK_00833 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LMMEADAK_00834 2.8e-165 yfhB 5.3.3.17 S PhzF family
LMMEADAK_00835 3.3e-106 yfhC C nitroreductase
LMMEADAK_00836 2.1e-25 yfhD S YfhD-like protein
LMMEADAK_00838 1.8e-167 yfhF S nucleoside-diphosphate sugar epimerase
LMMEADAK_00839 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
LMMEADAK_00840 9.7e-52 yfhH S Protein of unknown function (DUF1811)
LMMEADAK_00841 1.5e-206 yfhI EGP Major facilitator Superfamily
LMMEADAK_00843 4e-167 mpr 3.4.21.19 M Belongs to the peptidase S1B family
LMMEADAK_00844 2.2e-44 yfhJ S WVELL protein
LMMEADAK_00845 1.6e-94 batE T Bacterial SH3 domain homologues
LMMEADAK_00846 7.4e-34 yfhL S SdpI/YhfL protein family
LMMEADAK_00847 1.7e-170 yfhM S Alpha/beta hydrolase family
LMMEADAK_00848 4.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LMMEADAK_00849 0.0 yfhO S Bacterial membrane protein YfhO
LMMEADAK_00850 1.4e-184 yfhP S membrane-bound metal-dependent
LMMEADAK_00851 2.7e-210 mutY L A G-specific
LMMEADAK_00852 8.2e-37 yfhS
LMMEADAK_00853 5.8e-135 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_00855 7.5e-37 ygaB S YgaB-like protein
LMMEADAK_00856 2.2e-104 ygaC J Belongs to the UPF0374 family
LMMEADAK_00857 2.5e-306 ygaD V ABC transporter
LMMEADAK_00858 3.2e-179 ygaE S Membrane
LMMEADAK_00859 6.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LMMEADAK_00860 3.1e-86 bcp 1.11.1.15 O Peroxiredoxin
LMMEADAK_00861 1.8e-80 perR P Belongs to the Fur family
LMMEADAK_00862 1.5e-56 ygzB S UPF0295 protein
LMMEADAK_00863 3.7e-165 ygxA S Nucleotidyltransferase-like
LMMEADAK_00864 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_00869 7.8e-08
LMMEADAK_00877 1.6e-08
LMMEADAK_00881 2.6e-92 C Na+/H+ antiporter family
LMMEADAK_00882 3.5e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
LMMEADAK_00883 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LMMEADAK_00884 1.6e-264 ygaK C Berberine and berberine like
LMMEADAK_00886 6.3e-230 oppA5 E PFAM extracellular solute-binding protein family 5
LMMEADAK_00887 7.8e-137 appB P Binding-protein-dependent transport system inner membrane component
LMMEADAK_00888 9.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LMMEADAK_00889 1.4e-133 oppD3 P Belongs to the ABC transporter superfamily
LMMEADAK_00890 1.4e-133 oppF3 E Belongs to the ABC transporter superfamily
LMMEADAK_00891 2.1e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LMMEADAK_00892 7.5e-185 S Amidohydrolase
LMMEADAK_00893 9.3e-141 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
LMMEADAK_00894 3.5e-180 ssuA M Sulfonate ABC transporter
LMMEADAK_00895 3.4e-144 ssuC P ABC transporter (permease)
LMMEADAK_00896 3.2e-214 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
LMMEADAK_00897 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LMMEADAK_00898 9.6e-80 ygaO
LMMEADAK_00899 4.8e-23 K Transcriptional regulator
LMMEADAK_00901 4.6e-114 yhzB S B3/4 domain
LMMEADAK_00902 5.4e-225 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LMMEADAK_00903 1.1e-175 yhbB S Putative amidase domain
LMMEADAK_00904 6.9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LMMEADAK_00905 1.3e-108 yhbD K Protein of unknown function (DUF4004)
LMMEADAK_00906 8.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
LMMEADAK_00907 3.8e-64 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
LMMEADAK_00909 0.0 prkA T Ser protein kinase
LMMEADAK_00910 1.4e-215 yhbH S Belongs to the UPF0229 family
LMMEADAK_00911 4.6e-74 yhbI K DNA-binding transcription factor activity
LMMEADAK_00912 8.1e-98 yhbJ V COG1566 Multidrug resistance efflux pump
LMMEADAK_00913 8.4e-285 yhcA EGP Major facilitator Superfamily
LMMEADAK_00914 4.7e-99 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
LMMEADAK_00915 1.4e-54 yhcC
LMMEADAK_00916 9.6e-53
LMMEADAK_00917 2.5e-62 yhcF K Transcriptional regulator
LMMEADAK_00918 3e-125 yhcG V ABC transporter, ATP-binding protein
LMMEADAK_00919 4.1e-167 yhcH V ABC transporter, ATP-binding protein
LMMEADAK_00920 4.4e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
LMMEADAK_00921 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
LMMEADAK_00922 2.4e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
LMMEADAK_00923 7.1e-221 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LMMEADAK_00924 1.7e-50 yhcM
LMMEADAK_00925 5.7e-84 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LMMEADAK_00926 3.3e-161 yhcP
LMMEADAK_00927 4.5e-115 yhcQ M Spore coat protein
LMMEADAK_00928 0.0 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
LMMEADAK_00929 3.1e-107 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
LMMEADAK_00930 1.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LMMEADAK_00931 3.2e-68 yhcU S Family of unknown function (DUF5365)
LMMEADAK_00932 2.6e-68 yhcV S COG0517 FOG CBS domain
LMMEADAK_00933 4.9e-125 yhcW 5.4.2.6 S hydrolase
LMMEADAK_00934 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LMMEADAK_00935 3.8e-262 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LMMEADAK_00936 8.9e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
LMMEADAK_00937 3.5e-149 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
LMMEADAK_00938 1.9e-294 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LMMEADAK_00939 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LMMEADAK_00940 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LMMEADAK_00941 8.7e-204 yhcY 2.7.13.3 T Histidine kinase
LMMEADAK_00942 1.5e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LMMEADAK_00943 3.1e-87 azr 1.7.1.6 S NADPH-dependent FMN reductase
LMMEADAK_00944 2.5e-39 yhdB S YhdB-like protein
LMMEADAK_00945 5.3e-53 yhdC S Protein of unknown function (DUF3889)
LMMEADAK_00946 1e-217 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LMMEADAK_00947 1.9e-74 nsrR K Transcriptional regulator
LMMEADAK_00948 2.9e-255 ygxB M Conserved TM helix
LMMEADAK_00949 1.3e-270 ycgB S Stage V sporulation protein R
LMMEADAK_00950 4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
LMMEADAK_00951 1.7e-127 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LMMEADAK_00952 9e-164 citR K Transcriptional regulator
LMMEADAK_00953 1.3e-207 citA 2.3.3.1 C Belongs to the citrate synthase family
LMMEADAK_00954 1.6e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_00955 5.3e-251 yhdG E amino acid
LMMEADAK_00956 2e-199 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LMMEADAK_00957 8.1e-45 yhdK S Sigma-M inhibitor protein
LMMEADAK_00958 8.6e-201 yhdL S Sigma factor regulator N-terminal
LMMEADAK_00959 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
LMMEADAK_00960 5.1e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LMMEADAK_00961 4.3e-242 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LMMEADAK_00962 4.3e-71 cueR K transcriptional
LMMEADAK_00963 1.3e-226 yhdR 2.6.1.1 E Aminotransferase
LMMEADAK_00964 2.8e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LMMEADAK_00965 3.2e-256 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
LMMEADAK_00966 1.6e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LMMEADAK_00967 4.8e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LMMEADAK_00968 1.7e-128 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LMMEADAK_00970 1.6e-205 yhdY M Mechanosensitive ion channel
LMMEADAK_00971 1.3e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
LMMEADAK_00972 3.5e-157 yheN G deacetylase
LMMEADAK_00973 1.5e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
LMMEADAK_00974 1.8e-87 pksA K Transcriptional regulator
LMMEADAK_00975 1.2e-94 ymcC S Membrane
LMMEADAK_00976 2.1e-85 T universal stress protein
LMMEADAK_00978 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
LMMEADAK_00979 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
LMMEADAK_00980 2.1e-111 yheG GM NAD(P)H-binding
LMMEADAK_00982 5.8e-29 sspB S spore protein
LMMEADAK_00983 1.7e-36 yheE S Family of unknown function (DUF5342)
LMMEADAK_00984 2.5e-261 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
LMMEADAK_00985 4.8e-215 yheC HJ YheC/D like ATP-grasp
LMMEADAK_00986 1.9e-206 yheB S Belongs to the UPF0754 family
LMMEADAK_00987 4.4e-53 yheA S Belongs to the UPF0342 family
LMMEADAK_00988 6.1e-205 yhaZ L DNA alkylation repair enzyme
LMMEADAK_00989 3.3e-158 yhaX S haloacid dehalogenase-like hydrolase
LMMEADAK_00990 1.6e-293 hemZ H coproporphyrinogen III oxidase
LMMEADAK_00991 5.8e-252 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
LMMEADAK_00992 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
LMMEADAK_00993 6.6e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
LMMEADAK_00995 9e-136 yhaR 5.3.3.18 I enoyl-CoA hydratase
LMMEADAK_00996 7.3e-15 S YhzD-like protein
LMMEADAK_00997 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
LMMEADAK_00998 8e-206 yhaP CP COG1668 ABC-type Na efflux pump, permease component
LMMEADAK_00999 1.4e-234 yhaO L DNA repair exonuclease
LMMEADAK_01000 0.0 yhaN L AAA domain
LMMEADAK_01001 1.3e-176 yhaM L Shows a 3'-5' exoribonuclease activity
LMMEADAK_01002 1.6e-32 yhaL S Sporulation protein YhaL
LMMEADAK_01003 4.7e-126 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_01004 2.5e-42 L COG2963 Transposase and inactivated derivatives
LMMEADAK_01005 1.1e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
LMMEADAK_01006 7e-95 yhaK S Putative zincin peptidase
LMMEADAK_01007 9.9e-55 yhaI S Protein of unknown function (DUF1878)
LMMEADAK_01008 8.6e-113 hpr K Negative regulator of protease production and sporulation
LMMEADAK_01009 6.2e-39 yhaH S YtxH-like protein
LMMEADAK_01010 2e-17
LMMEADAK_01011 3.8e-77 trpP S Tryptophan transporter TrpP
LMMEADAK_01012 3.5e-202 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LMMEADAK_01013 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LMMEADAK_01014 1.1e-135 ecsA V transporter (ATP-binding protein)
LMMEADAK_01015 4.2e-220 ecsB U ABC transporter
LMMEADAK_01016 2.8e-123 ecsC S EcsC protein family
LMMEADAK_01017 1.6e-224 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LMMEADAK_01018 4.8e-244 yhfA C membrane
LMMEADAK_01019 3.2e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
LMMEADAK_01020 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LMMEADAK_01021 8.6e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LMMEADAK_01022 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LMMEADAK_01023 1.4e-275 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LMMEADAK_01024 2.7e-100 yhgD K Transcriptional regulator
LMMEADAK_01025 1.2e-276 yhgE S YhgE Pip N-terminal domain protein
LMMEADAK_01026 3.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LMMEADAK_01028 7.8e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
LMMEADAK_01029 7.4e-223 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
LMMEADAK_01030 7.9e-11 yhfH S YhfH-like protein
LMMEADAK_01031 1.5e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
LMMEADAK_01032 5.9e-188 lplJ 6.3.1.20 H Lipoate-protein ligase
LMMEADAK_01033 1e-111 yhfK GM NmrA-like family
LMMEADAK_01034 6.4e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LMMEADAK_01035 1.9e-65 yhfM
LMMEADAK_01036 1.7e-237 yhfN 3.4.24.84 O Peptidase M48
LMMEADAK_01037 4.3e-206 aprE 3.4.21.62 O Belongs to the peptidase S8 family
LMMEADAK_01038 1.1e-158 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
LMMEADAK_01039 1.7e-102 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
LMMEADAK_01040 1.6e-202 vraB 2.3.1.9 I Belongs to the thiolase family
LMMEADAK_01041 1.3e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
LMMEADAK_01042 9.3e-90 bioY S BioY family
LMMEADAK_01043 5.9e-196 hemAT NT chemotaxis protein
LMMEADAK_01044 9.7e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
LMMEADAK_01045 6.5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_01046 1.7e-32 yhzC S IDEAL
LMMEADAK_01047 1.9e-109 comK K Competence transcription factor
LMMEADAK_01048 3.9e-68 frataxin S Domain of unknown function (DU1801)
LMMEADAK_01049 1.3e-66 frataxin S Domain of unknown function (DU1801)
LMMEADAK_01050 1.3e-93 mepB S MepB protein
LMMEADAK_01051 1.6e-126 yrpD S Domain of unknown function, YrpD
LMMEADAK_01052 1.6e-42 yhjA S Excalibur calcium-binding domain
LMMEADAK_01053 3.3e-47 S Belongs to the UPF0145 family
LMMEADAK_01054 2.5e-267 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LMMEADAK_01055 1.4e-27 yhjC S Protein of unknown function (DUF3311)
LMMEADAK_01056 3.2e-59 yhjD
LMMEADAK_01057 8.2e-111 yhjE S SNARE associated Golgi protein
LMMEADAK_01058 1.6e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
LMMEADAK_01059 3.1e-273 yhjG CH FAD binding domain
LMMEADAK_01060 2.4e-92 yhjH K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_01061 4.3e-182 abrB S membrane
LMMEADAK_01062 6.2e-208 blt EGP Major facilitator Superfamily
LMMEADAK_01063 4.5e-109 K QacR-like protein, C-terminal region
LMMEADAK_01064 6.3e-93 yhjR S Rubrerythrin
LMMEADAK_01065 6.5e-66 ydfS S Protein of unknown function (DUF421)
LMMEADAK_01067 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
LMMEADAK_01068 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LMMEADAK_01069 4.3e-222 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LMMEADAK_01070 0.0 sbcC L COG0419 ATPase involved in DNA repair
LMMEADAK_01071 1.3e-50 yisB V COG1403 Restriction endonuclease
LMMEADAK_01072 5.9e-32 gerPF S Spore germination protein gerPA/gerPF
LMMEADAK_01073 1.2e-62 gerPE S Spore germination protein GerPE
LMMEADAK_01074 3.1e-23 gerPD S Spore germination protein
LMMEADAK_01075 9.1e-62 gerPC S Spore germination protein
LMMEADAK_01076 6.2e-35 gerPB S cell differentiation
LMMEADAK_01077 8.4e-34 gerPA S Spore germination protein
LMMEADAK_01078 5e-07 yisI S Spo0E like sporulation regulatory protein
LMMEADAK_01079 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
LMMEADAK_01080 1.1e-59 yisL S UPF0344 protein
LMMEADAK_01081 1.4e-98 yisN S Protein of unknown function (DUF2777)
LMMEADAK_01082 0.0 asnO 6.3.5.4 E Asparagine synthase
LMMEADAK_01083 1.3e-134 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
LMMEADAK_01084 1.9e-245 yisQ V Mate efflux family protein
LMMEADAK_01085 1.7e-159 yisR K Transcriptional regulator
LMMEADAK_01086 3.9e-25 yisS 1.1.1.370 S Oxidoreductase family, NAD-binding Rossmann fold
LMMEADAK_01087 3.7e-90 yisT S DinB family
LMMEADAK_01088 1.2e-74 argO S Lysine exporter protein LysE YggA
LMMEADAK_01089 6.4e-191 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LMMEADAK_01090 1.1e-70 mcbG S Pentapeptide repeats (9 copies)
LMMEADAK_01091 1.2e-79 yjcF S Acetyltransferase (GNAT) domain
LMMEADAK_01092 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
LMMEADAK_01093 4.3e-54 yajQ S Belongs to the UPF0234 family
LMMEADAK_01094 9e-161 cvfB S protein conserved in bacteria
LMMEADAK_01095 6.9e-173 yufN S ABC transporter substrate-binding protein PnrA-like
LMMEADAK_01096 1.5e-233 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
LMMEADAK_01097 5.3e-242 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
LMMEADAK_01099 5.5e-158 yitS S protein conserved in bacteria
LMMEADAK_01100 3.9e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
LMMEADAK_01101 5.5e-80 ipi S Intracellular proteinase inhibitor
LMMEADAK_01102 4.4e-26 S Protein of unknown function (DUF3813)
LMMEADAK_01103 3.5e-07
LMMEADAK_01104 2.7e-154 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
LMMEADAK_01105 3.1e-144 yjfP S COG1073 Hydrolases of the alpha beta superfamily
LMMEADAK_01106 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
LMMEADAK_01107 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
LMMEADAK_01108 8.6e-273 yitY C D-arabinono-1,4-lactone oxidase
LMMEADAK_01109 4.1e-90 norB G Major Facilitator Superfamily
LMMEADAK_01110 1.1e-195 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LMMEADAK_01111 7.2e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LMMEADAK_01112 3.7e-137 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
LMMEADAK_01113 6.8e-220 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LMMEADAK_01114 6.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LMMEADAK_01115 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
LMMEADAK_01116 1.7e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LMMEADAK_01117 1.1e-40 L transposase activity
LMMEADAK_01118 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_01119 1.2e-27 yjzC S YjzC-like protein
LMMEADAK_01120 3.3e-23 yjzD S Protein of unknown function (DUF2929)
LMMEADAK_01121 1.1e-138 yjaU I carboxylic ester hydrolase activity
LMMEADAK_01122 3.6e-105 yjaV
LMMEADAK_01123 7.2e-166 med S Transcriptional activator protein med
LMMEADAK_01124 1.1e-26 comZ S ComZ
LMMEADAK_01125 5.9e-32 yjzB
LMMEADAK_01126 1.1e-172 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LMMEADAK_01127 4.9e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LMMEADAK_01128 2.1e-148 yjaZ O Zn-dependent protease
LMMEADAK_01129 3.3e-183 appD P Belongs to the ABC transporter superfamily
LMMEADAK_01130 2.2e-187 appF E Belongs to the ABC transporter superfamily
LMMEADAK_01131 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
LMMEADAK_01132 2.2e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LMMEADAK_01133 1.4e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LMMEADAK_01134 5.5e-146 yjbA S Belongs to the UPF0736 family
LMMEADAK_01135 5.2e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LMMEADAK_01136 0.0 oppA E ABC transporter substrate-binding protein
LMMEADAK_01137 9.2e-167 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LMMEADAK_01138 2.9e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LMMEADAK_01139 2.7e-202 oppD P Belongs to the ABC transporter superfamily
LMMEADAK_01140 2.1e-171 oppF E Belongs to the ABC transporter superfamily
LMMEADAK_01141 2e-230 S Putative glycosyl hydrolase domain
LMMEADAK_01142 2e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LMMEADAK_01143 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LMMEADAK_01144 3.6e-109 yjbE P Integral membrane protein TerC family
LMMEADAK_01145 2e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LMMEADAK_01146 1.1e-220 yjbF S Competence protein
LMMEADAK_01147 0.0 pepF E oligoendopeptidase F
LMMEADAK_01148 5.8e-19
LMMEADAK_01149 6.6e-170 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LMMEADAK_01150 4.8e-72 yjbI S Bacterial-like globin
LMMEADAK_01151 4.5e-118 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LMMEADAK_01152 6e-100 yjbK S protein conserved in bacteria
LMMEADAK_01153 6e-61 yjbL S Belongs to the UPF0738 family
LMMEADAK_01154 2.3e-108 yjbM 2.7.6.5 S GTP pyrophosphokinase
LMMEADAK_01155 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LMMEADAK_01156 4.8e-165 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LMMEADAK_01157 1.4e-144 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
LMMEADAK_01158 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
LMMEADAK_01159 2e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LMMEADAK_01160 5.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
LMMEADAK_01161 1.1e-211 thiO 1.4.3.19 E Glycine oxidase
LMMEADAK_01162 2.6e-29 thiS H Thiamine biosynthesis
LMMEADAK_01163 5.8e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
LMMEADAK_01164 7.1e-189 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LMMEADAK_01165 3.7e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LMMEADAK_01166 4e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
LMMEADAK_01167 3e-89 yjbX S Spore coat protein
LMMEADAK_01168 2.6e-79 cotZ S Spore coat protein
LMMEADAK_01169 8.1e-90 cotY S Spore coat protein Z
LMMEADAK_01170 4.2e-73 cotX S Spore Coat Protein X and V domain
LMMEADAK_01171 2.3e-21 cotW
LMMEADAK_01172 1.1e-54 cotV S Spore Coat Protein X and V domain
LMMEADAK_01173 5.6e-56 yjcA S Protein of unknown function (DUF1360)
LMMEADAK_01177 3.8e-38 spoVIF S Stage VI sporulation protein F
LMMEADAK_01178 0.0 yjcD 3.6.4.12 L DNA helicase
LMMEADAK_01179 5.1e-35
LMMEADAK_01180 3.7e-142 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
LMMEADAK_01181 3.4e-124 S ABC-2 type transporter
LMMEADAK_01182 1.8e-133 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
LMMEADAK_01183 9.4e-36 K SpoVT / AbrB like domain
LMMEADAK_01184 4.2e-74 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LMMEADAK_01185 3.5e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
LMMEADAK_01186 5.5e-127 yjcH P COG2382 Enterochelin esterase and related enzymes
LMMEADAK_01187 5.4e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LMMEADAK_01188 1.3e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LMMEADAK_01191 8.2e-57
LMMEADAK_01192 1.3e-34 yobL S Bacterial EndoU nuclease
LMMEADAK_01193 1.1e-07 yobL L Belongs to the WXG100 family
LMMEADAK_01194 2.6e-92
LMMEADAK_01197 5.6e-132
LMMEADAK_01198 8.3e-10 ywlA S Uncharacterised protein family (UPF0715)
LMMEADAK_01199 2.4e-12
LMMEADAK_01200 4.7e-49 FG HIT domain
LMMEADAK_01201 1.5e-72 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
LMMEADAK_01206 2.5e-164 bla 3.5.2.6 V beta-lactamase
LMMEADAK_01207 8.4e-47 yjcS S Antibiotic biosynthesis monooxygenase
LMMEADAK_01208 5.9e-250 yfjF EGP Belongs to the major facilitator superfamily
LMMEADAK_01209 1.1e-80 napB K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_01210 2e-221 ganA 3.2.1.89 G arabinogalactan
LMMEADAK_01211 9.9e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LMMEADAK_01212 2.2e-190 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LMMEADAK_01213 1.1e-214 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LMMEADAK_01214 9.4e-311 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LMMEADAK_01215 2e-49 lacF 2.7.1.207 G phosphotransferase system
LMMEADAK_01216 1.7e-281 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
LMMEADAK_01217 3.3e-138 lacR K COG1349 Transcriptional regulators of sugar metabolism
LMMEADAK_01218 1.4e-124 5.4.2.6 S Haloacid dehalogenase-like hydrolase
LMMEADAK_01219 2.6e-34
LMMEADAK_01220 2.9e-51 K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_01221 8.1e-106 yhiD S MgtC SapB transporter
LMMEADAK_01223 8.3e-21 yjfB S Putative motility protein
LMMEADAK_01224 2.5e-68 T PhoQ Sensor
LMMEADAK_01225 1.4e-101 yjgB S Domain of unknown function (DUF4309)
LMMEADAK_01226 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
LMMEADAK_01227 4.3e-92 yjgD S Protein of unknown function (DUF1641)
LMMEADAK_01228 4.2e-228 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
LMMEADAK_01229 1.4e-223 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
LMMEADAK_01230 6.8e-29
LMMEADAK_01231 6.1e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LMMEADAK_01232 1.8e-123 ybbM S transport system, permease component
LMMEADAK_01233 1.7e-131 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
LMMEADAK_01234 1.4e-178 yjlA EG Putative multidrug resistance efflux transporter
LMMEADAK_01235 7.5e-91 yjlB S Cupin domain
LMMEADAK_01236 7e-66 yjlC S Protein of unknown function (DUF1641)
LMMEADAK_01237 3.5e-219 yjlD 1.6.99.3 C NADH dehydrogenase
LMMEADAK_01238 4.8e-276 uxaC 5.3.1.12 G glucuronate isomerase
LMMEADAK_01239 3.3e-253 yjmB G symporter YjmB
LMMEADAK_01240 6.4e-182 exuR K transcriptional
LMMEADAK_01241 1.6e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
LMMEADAK_01242 9.9e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
LMMEADAK_01243 3.9e-131 MA20_18170 S membrane transporter protein
LMMEADAK_01244 6.2e-79 yjoA S DinB family
LMMEADAK_01245 4.9e-215 S response regulator aspartate phosphatase
LMMEADAK_01247 1.4e-165 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
LMMEADAK_01248 1.4e-60 yjqA S Bacterial PH domain
LMMEADAK_01249 4.7e-111 yjqB S phage-related replication protein
LMMEADAK_01250 3.6e-09 xkdA E IrrE N-terminal-like domain
LMMEADAK_01251 7.8e-111 xkdA E IrrE N-terminal-like domain
LMMEADAK_01252 1.1e-56 xre K Helix-turn-helix XRE-family like proteins
LMMEADAK_01254 6.5e-153 xkdC L Bacterial dnaA protein
LMMEADAK_01257 2e-10 yqaO S Phage-like element PBSX protein XtrA
LMMEADAK_01258 2.8e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
LMMEADAK_01259 8.9e-110 xtmA L phage terminase small subunit
LMMEADAK_01260 7.9e-209 xtmB S phage terminase, large subunit
LMMEADAK_01261 1e-241 yqbA S portal protein
LMMEADAK_01262 5.7e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
LMMEADAK_01263 1e-157 xkdG S Phage capsid family
LMMEADAK_01264 5.7e-46 yqbG S Protein of unknown function (DUF3199)
LMMEADAK_01265 4.2e-43 yqbH S Domain of unknown function (DUF3599)
LMMEADAK_01266 3.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
LMMEADAK_01267 4.9e-57 xkdJ
LMMEADAK_01268 8.2e-15
LMMEADAK_01269 1e-225 xkdK S Phage tail sheath C-terminal domain
LMMEADAK_01270 2e-74 xkdM S Phage tail tube protein
LMMEADAK_01271 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
LMMEADAK_01272 3.4e-19
LMMEADAK_01273 1.6e-188 xkdO L Transglycosylase SLT domain
LMMEADAK_01274 1e-111 xkdP S Lysin motif
LMMEADAK_01275 3.6e-161 xkdQ 3.2.1.96 G NLP P60 protein
LMMEADAK_01276 2.7e-31 xkdR S Protein of unknown function (DUF2577)
LMMEADAK_01277 7.2e-58 xkdS S Protein of unknown function (DUF2634)
LMMEADAK_01278 5.1e-166 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
LMMEADAK_01279 5e-86 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
LMMEADAK_01280 4.2e-27
LMMEADAK_01281 7.7e-68
LMMEADAK_01283 1.1e-29 xkdX
LMMEADAK_01284 3.6e-137 xepA
LMMEADAK_01285 8.7e-38 xhlA S Haemolysin XhlA
LMMEADAK_01286 1.3e-38 xhlB S SPP1 phage holin
LMMEADAK_01287 2.7e-168 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LMMEADAK_01288 8.7e-23 spoIISB S Stage II sporulation protein SB
LMMEADAK_01289 2.4e-133 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
LMMEADAK_01290 2e-175 pit P phosphate transporter
LMMEADAK_01291 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
LMMEADAK_01292 1.9e-242 steT E amino acid
LMMEADAK_01293 1.4e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
LMMEADAK_01294 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LMMEADAK_01295 2.9e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LMMEADAK_01297 3.8e-206 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LMMEADAK_01298 1e-287 yubD P Major Facilitator Superfamily
LMMEADAK_01300 6.5e-156 dppA E D-aminopeptidase
LMMEADAK_01301 6.4e-160 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LMMEADAK_01302 1.1e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LMMEADAK_01303 2.9e-190 dppD P Belongs to the ABC transporter superfamily
LMMEADAK_01304 0.0 dppE E ABC transporter substrate-binding protein
LMMEADAK_01305 1.1e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LMMEADAK_01306 2.6e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
LMMEADAK_01307 1.6e-171 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LMMEADAK_01308 4.3e-183 ykfD E Belongs to the ABC transporter superfamily
LMMEADAK_01309 2.3e-206 pgl 3.1.1.31 G 6-phosphogluconolactonase
LMMEADAK_01310 5e-159 ykgA E Amidinotransferase
LMMEADAK_01311 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
LMMEADAK_01312 1.6e-102 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LMMEADAK_01313 9.4e-53 ykkC P Multidrug resistance protein
LMMEADAK_01314 3.4e-49 ykkD P Multidrug resistance protein
LMMEADAK_01315 7.8e-171 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
LMMEADAK_01316 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LMMEADAK_01317 3.6e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LMMEADAK_01318 1.3e-70 ohrA O Organic hydroperoxide resistance protein
LMMEADAK_01319 2.2e-85 ohrR K COG1846 Transcriptional regulators
LMMEADAK_01320 4.2e-71 ohrB O Organic hydroperoxide resistance protein
LMMEADAK_01321 8.9e-59 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LMMEADAK_01323 1.5e-216 M Glycosyl transferase family 2
LMMEADAK_01324 6e-123 M PFAM Collagen triple helix repeat (20 copies)
LMMEADAK_01325 1.6e-216 hcaT 1.5.1.2 EGP Major facilitator Superfamily
LMMEADAK_01326 4e-119 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LMMEADAK_01327 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LMMEADAK_01328 7.7e-177 isp O Belongs to the peptidase S8 family
LMMEADAK_01329 3.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LMMEADAK_01330 3.5e-132 ykoC P Cobalt transport protein
LMMEADAK_01331 2e-305 P ABC transporter, ATP-binding protein
LMMEADAK_01332 3.4e-98 ykoE S ABC-type cobalt transport system, permease component
LMMEADAK_01333 1e-245 ydhD M Glycosyl hydrolase
LMMEADAK_01335 2.2e-238 mgtE P Acts as a magnesium transporter
LMMEADAK_01336 5.4e-53 tnrA K transcriptional
LMMEADAK_01337 1.9e-16
LMMEADAK_01338 3.1e-26 ykoL
LMMEADAK_01339 5e-81 ykoM K transcriptional
LMMEADAK_01340 2.2e-99 ykoP G polysaccharide deacetylase
LMMEADAK_01341 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
LMMEADAK_01342 4.2e-153 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LMMEADAK_01343 4.5e-100 ykoX S membrane-associated protein
LMMEADAK_01344 4.6e-135 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
LMMEADAK_01345 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LMMEADAK_01346 3.1e-119 rsgI S Anti-sigma factor N-terminus
LMMEADAK_01347 2.5e-26 sspD S small acid-soluble spore protein
LMMEADAK_01348 4.3e-124 ykrK S Domain of unknown function (DUF1836)
LMMEADAK_01349 4.1e-156 htpX O Belongs to the peptidase M48B family
LMMEADAK_01350 5.7e-41 L COG2963 Transposase and inactivated derivatives
LMMEADAK_01351 5.8e-101 L Integrase core domain
LMMEADAK_01352 1.4e-240 ktrB P COG0168 Trk-type K transport systems, membrane components
LMMEADAK_01353 1.1e-45 ydfR S Protein of unknown function (DUF421)
LMMEADAK_01354 3.8e-54 ydfR S Protein of unknown function (DUF421)
LMMEADAK_01355 7.9e-24 ykzE
LMMEADAK_01356 9.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
LMMEADAK_01357 0.0 kinE 2.7.13.3 T Histidine kinase
LMMEADAK_01358 2.1e-85 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LMMEADAK_01360 1.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LMMEADAK_01361 1e-226 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LMMEADAK_01362 2.9e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LMMEADAK_01363 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
LMMEADAK_01364 4.3e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
LMMEADAK_01365 1.4e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
LMMEADAK_01366 9.4e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
LMMEADAK_01367 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LMMEADAK_01368 3.4e-10 S Spo0E like sporulation regulatory protein
LMMEADAK_01369 4.3e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
LMMEADAK_01370 1.5e-77 ykvE K transcriptional
LMMEADAK_01371 2.7e-127 motB N Flagellar motor protein
LMMEADAK_01372 1.1e-136 motA N flagellar motor
LMMEADAK_01373 0.0 clpE O Belongs to the ClpA ClpB family
LMMEADAK_01374 1.4e-184 ykvI S membrane
LMMEADAK_01375 2.2e-191
LMMEADAK_01376 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LMMEADAK_01377 6.3e-81 queD 4.1.2.50, 4.2.3.12 H synthase
LMMEADAK_01378 1.9e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LMMEADAK_01379 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LMMEADAK_01381 6.4e-60 ykvN K HxlR-like helix-turn-helix
LMMEADAK_01382 2.7e-132 IQ Enoyl-(Acyl carrier protein) reductase
LMMEADAK_01383 1.5e-36 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LMMEADAK_01384 2.1e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
LMMEADAK_01385 1.3e-34 3.5.1.104 M LysM domain
LMMEADAK_01386 2e-161 G Glycosyl hydrolases family 18
LMMEADAK_01388 5e-44 ykvR S Protein of unknown function (DUF3219)
LMMEADAK_01389 7.8e-25 ykvS S protein conserved in bacteria
LMMEADAK_01390 2.3e-27
LMMEADAK_01391 2.4e-110 ykvT 3.5.1.28 M Cell Wall Hydrolase
LMMEADAK_01392 6.2e-241 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LMMEADAK_01393 5.9e-88 stoA CO thiol-disulfide
LMMEADAK_01394 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LMMEADAK_01395 4.1e-206 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LMMEADAK_01397 3.9e-176 ykvZ 5.1.1.1 K Transcriptional regulator
LMMEADAK_01398 5.1e-156 glcT K antiterminator
LMMEADAK_01399 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LMMEADAK_01400 2.1e-39 ptsH G phosphocarrier protein HPr
LMMEADAK_01401 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LMMEADAK_01402 6.1e-38 splA S Transcriptional regulator
LMMEADAK_01403 6.5e-190 splB 4.1.99.14 L Spore photoproduct lyase
LMMEADAK_01404 1.2e-264 mcpC NT chemotaxis protein
LMMEADAK_01405 3.6e-157 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
LMMEADAK_01406 3.3e-93 ykwD J protein with SCP PR1 domains
LMMEADAK_01407 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
LMMEADAK_01408 4.4e-290 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
LMMEADAK_01409 3.9e-215 patA 2.6.1.1 E Aminotransferase
LMMEADAK_01410 2.3e-09
LMMEADAK_01411 1.8e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
LMMEADAK_01412 1.4e-83 ykyB S YkyB-like protein
LMMEADAK_01413 1.3e-240 ykuC EGP Major facilitator Superfamily
LMMEADAK_01414 1.3e-87 ykuD S protein conserved in bacteria
LMMEADAK_01415 6.1e-157 ykuE S Metallophosphoesterase
LMMEADAK_01416 4.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_01418 7.4e-233 ykuI T Diguanylate phosphodiesterase
LMMEADAK_01419 3.9e-37 ykuJ S protein conserved in bacteria
LMMEADAK_01420 4.9e-93 ykuK S Ribonuclease H-like
LMMEADAK_01421 2.5e-26 ykzF S Antirepressor AbbA
LMMEADAK_01422 1e-75 ykuL S CBS domain
LMMEADAK_01423 4.6e-168 ccpC K Transcriptional regulator
LMMEADAK_01424 3e-89 fld C Flavodoxin
LMMEADAK_01425 1e-170 ykuO
LMMEADAK_01426 2.7e-79 fld C Flavodoxin
LMMEADAK_01427 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LMMEADAK_01428 5.3e-217 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LMMEADAK_01429 4.8e-38 ykuS S Belongs to the UPF0180 family
LMMEADAK_01430 4.9e-140 ykuT M Mechanosensitive ion channel
LMMEADAK_01431 4.9e-14 ykuV CO thiol-disulfide
LMMEADAK_01432 3.2e-53 ykuV CO thiol-disulfide
LMMEADAK_01433 1.3e-97 rok K Repressor of ComK
LMMEADAK_01434 8.6e-163 yknT
LMMEADAK_01435 5.3e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
LMMEADAK_01436 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LMMEADAK_01437 1.3e-243 moeA 2.10.1.1 H molybdopterin
LMMEADAK_01438 2.6e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
LMMEADAK_01439 7.9e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
LMMEADAK_01440 1.5e-33 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LMMEADAK_01441 1.7e-104 yknW S Yip1 domain
LMMEADAK_01442 2e-171 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LMMEADAK_01443 7.4e-121 macB V ABC transporter, ATP-binding protein
LMMEADAK_01444 1e-210 yknZ V ABC transporter (permease)
LMMEADAK_01445 6.6e-131 fruR K Transcriptional regulator
LMMEADAK_01446 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
LMMEADAK_01447 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
LMMEADAK_01448 4.3e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LMMEADAK_01449 1.5e-37 ykoA
LMMEADAK_01450 2.2e-309 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
LMMEADAK_01451 1.1e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LMMEADAK_01452 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LMMEADAK_01453 5.5e-12 S Uncharacterized protein YkpC
LMMEADAK_01454 6.9e-184 mreB D Rod-share determining protein MreBH
LMMEADAK_01455 2.1e-45 abrB K of stationary sporulation gene expression
LMMEADAK_01456 3.7e-246 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
LMMEADAK_01457 3.8e-148 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
LMMEADAK_01458 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
LMMEADAK_01459 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LMMEADAK_01460 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LMMEADAK_01461 8.2e-31 ykzG S Belongs to the UPF0356 family
LMMEADAK_01462 3.9e-147 ykrA S hydrolases of the HAD superfamily
LMMEADAK_01463 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LMMEADAK_01465 5.8e-104 recN L Putative cell-wall binding lipoprotein
LMMEADAK_01466 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LMMEADAK_01467 0.0 Q Polyketide synthase of type I
LMMEADAK_01468 0.0 Q polyketide synthase
LMMEADAK_01469 0.0 Q Polyketide synthase of type I
LMMEADAK_01470 0.0 Q Polyketide synthase of type I
LMMEADAK_01471 0.0 Q Polyketide synthase of type I
LMMEADAK_01472 0.0 Q Polyketide synthase of type I
LMMEADAK_01473 0.0 bioH 2.1.1.197, 3.1.1.85, 4.2.99.20 IQ Phosphopantetheine attachment site
LMMEADAK_01474 9.3e-211 V Beta-lactamase
LMMEADAK_01475 2.7e-205 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LMMEADAK_01476 1.4e-178 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LMMEADAK_01477 3.4e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LMMEADAK_01478 5e-241 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LMMEADAK_01479 3e-44 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
LMMEADAK_01480 3.7e-140 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
LMMEADAK_01481 3.1e-278 speA 4.1.1.19 E Arginine
LMMEADAK_01482 1.6e-42 yktA S Belongs to the UPF0223 family
LMMEADAK_01483 4.9e-119 yktB S Belongs to the UPF0637 family
LMMEADAK_01484 6.3e-24 ykzI
LMMEADAK_01485 6.1e-151 suhB 3.1.3.25 G Inositol monophosphatase
LMMEADAK_01486 1.8e-83 ykzC S Acetyltransferase (GNAT) family
LMMEADAK_01487 2.7e-296 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
LMMEADAK_01488 3.1e-193 ylaA
LMMEADAK_01489 8.9e-46 ylaB
LMMEADAK_01490 3.2e-92 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
LMMEADAK_01491 1.7e-13 sigC S Putative zinc-finger
LMMEADAK_01492 6.3e-39 ylaE
LMMEADAK_01493 6.7e-24 S Family of unknown function (DUF5325)
LMMEADAK_01494 0.0 typA T GTP-binding protein TypA
LMMEADAK_01495 1.7e-48 ylaH S YlaH-like protein
LMMEADAK_01496 1e-33 ylaI S protein conserved in bacteria
LMMEADAK_01497 3.3e-104 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LMMEADAK_01498 3.7e-246 phoH T ATPase related to phosphate starvation-inducible protein PhoH
LMMEADAK_01499 2.2e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LMMEADAK_01500 7e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
LMMEADAK_01501 8.7e-44 ylaN S Belongs to the UPF0358 family
LMMEADAK_01502 7.7e-214 ftsW D Belongs to the SEDS family
LMMEADAK_01503 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LMMEADAK_01504 2.9e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
LMMEADAK_01505 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
LMMEADAK_01506 1.5e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
LMMEADAK_01507 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LMMEADAK_01508 2.4e-110 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
LMMEADAK_01509 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
LMMEADAK_01510 1.4e-164 ctaG S cytochrome c oxidase
LMMEADAK_01511 8.5e-60 ylbA S YugN-like family
LMMEADAK_01512 2.2e-73 ylbB T COG0517 FOG CBS domain
LMMEADAK_01513 1.3e-198 ylbC S protein with SCP PR1 domains
LMMEADAK_01514 6.1e-54 ylbD S Putative coat protein
LMMEADAK_01515 8.8e-37 ylbE S YlbE-like protein
LMMEADAK_01516 1.2e-71 ylbF S Belongs to the UPF0342 family
LMMEADAK_01517 7.2e-43 ylbG S UPF0298 protein
LMMEADAK_01518 8.5e-90 rsmD 2.1.1.171 L Methyltransferase
LMMEADAK_01519 3.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LMMEADAK_01520 9.8e-217 ylbJ S Sporulation integral membrane protein YlbJ
LMMEADAK_01521 8.9e-139 ylbK S esterase of the alpha-beta hydrolase superfamily
LMMEADAK_01522 2.1e-188 ylbL T Belongs to the peptidase S16 family
LMMEADAK_01523 4.6e-230 ylbM S Belongs to the UPF0348 family
LMMEADAK_01524 7.8e-91 yceD S metal-binding, possibly nucleic acid-binding protein
LMMEADAK_01525 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LMMEADAK_01526 4.5e-71 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
LMMEADAK_01527 1.2e-88 ylbP K n-acetyltransferase
LMMEADAK_01528 1.1e-164 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LMMEADAK_01529 1.2e-310 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
LMMEADAK_01530 8.9e-78 mraZ K Belongs to the MraZ family
LMMEADAK_01531 2.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LMMEADAK_01532 2.9e-52 ftsL D Essential cell division protein
LMMEADAK_01533 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
LMMEADAK_01534 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
LMMEADAK_01535 1.5e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LMMEADAK_01536 1.7e-171 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LMMEADAK_01537 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LMMEADAK_01538 2.2e-185 spoVE D Belongs to the SEDS family
LMMEADAK_01539 2.1e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LMMEADAK_01540 5.6e-169 murB 1.3.1.98 M cell wall formation
LMMEADAK_01541 3e-134 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LMMEADAK_01542 2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LMMEADAK_01543 1.2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LMMEADAK_01544 0.0 bpr O COG1404 Subtilisin-like serine proteases
LMMEADAK_01545 1.5e-161 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
LMMEADAK_01546 6.8e-117 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LMMEADAK_01547 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LMMEADAK_01548 1e-145 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
LMMEADAK_01549 3.8e-256 argE 3.5.1.16 E Acetylornithine deacetylase
LMMEADAK_01550 2.2e-38 ylmC S sporulation protein
LMMEADAK_01551 3.4e-160 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
LMMEADAK_01552 1.6e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LMMEADAK_01553 4.8e-60 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
LMMEADAK_01554 5.2e-41 yggT S membrane
LMMEADAK_01555 5.5e-141 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
LMMEADAK_01556 8.9e-68 divIVA D Cell division initiation protein
LMMEADAK_01557 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LMMEADAK_01558 3.4e-64 dksA T COG1734 DnaK suppressor protein
LMMEADAK_01559 5.2e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LMMEADAK_01560 2.3e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LMMEADAK_01561 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LMMEADAK_01562 8e-233 pyrP F Xanthine uracil
LMMEADAK_01563 1.2e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LMMEADAK_01564 3e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LMMEADAK_01565 6.1e-210 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
LMMEADAK_01566 0.0 carB 6.3.5.5 F Belongs to the CarB family
LMMEADAK_01567 4.2e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LMMEADAK_01568 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LMMEADAK_01569 2.7e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LMMEADAK_01570 9.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LMMEADAK_01572 3.2e-140 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
LMMEADAK_01573 1.7e-177 cysP P phosphate transporter
LMMEADAK_01574 8.6e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
LMMEADAK_01575 3.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
LMMEADAK_01576 4.5e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
LMMEADAK_01577 6.4e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
LMMEADAK_01578 3.8e-79 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
LMMEADAK_01579 2.2e-137 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_01580 1.2e-44 L COG2963 Transposase and inactivated derivatives
LMMEADAK_01581 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LMMEADAK_01582 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
LMMEADAK_01583 7.7e-155 yloC S stress-induced protein
LMMEADAK_01584 1.5e-40 ylzA S Belongs to the UPF0296 family
LMMEADAK_01585 8.1e-111 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LMMEADAK_01586 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
LMMEADAK_01587 1.3e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LMMEADAK_01588 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LMMEADAK_01589 2.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LMMEADAK_01590 1.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LMMEADAK_01591 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LMMEADAK_01592 9e-206 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LMMEADAK_01593 1.7e-139 stp 3.1.3.16 T phosphatase
LMMEADAK_01594 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LMMEADAK_01595 1.7e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LMMEADAK_01596 5.7e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LMMEADAK_01597 7.6e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
LMMEADAK_01598 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LMMEADAK_01599 5.5e-59 asp S protein conserved in bacteria
LMMEADAK_01600 7.1e-303 yloV S kinase related to dihydroxyacetone kinase
LMMEADAK_01601 1.6e-117 sdaAB 4.3.1.17 E L-serine dehydratase
LMMEADAK_01602 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
LMMEADAK_01603 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LMMEADAK_01604 2e-92 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
LMMEADAK_01605 3.6e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LMMEADAK_01606 7e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LMMEADAK_01607 4.6e-129 IQ reductase
LMMEADAK_01608 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LMMEADAK_01609 1.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LMMEADAK_01610 0.0 smc D Required for chromosome condensation and partitioning
LMMEADAK_01611 2.8e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LMMEADAK_01612 1.8e-139 S Phosphotransferase enzyme family
LMMEADAK_01613 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LMMEADAK_01614 3.1e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LMMEADAK_01615 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LMMEADAK_01616 3.8e-35 ylqC S Belongs to the UPF0109 family
LMMEADAK_01617 1.3e-61 ylqD S YlqD protein
LMMEADAK_01618 5.9e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LMMEADAK_01619 1.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LMMEADAK_01620 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LMMEADAK_01621 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LMMEADAK_01622 3.4e-127 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LMMEADAK_01623 6.4e-307 ylqG
LMMEADAK_01624 6.7e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
LMMEADAK_01625 6.8e-212 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
LMMEADAK_01626 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LMMEADAK_01627 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
LMMEADAK_01628 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LMMEADAK_01629 9.7e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LMMEADAK_01630 7.2e-172 xerC L tyrosine recombinase XerC
LMMEADAK_01631 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LMMEADAK_01632 4.5e-234 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LMMEADAK_01633 1.2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LMMEADAK_01634 1.8e-47 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
LMMEADAK_01635 2.4e-75 flgC N Belongs to the flagella basal body rod proteins family
LMMEADAK_01636 2.5e-31 fliE N Flagellar hook-basal body
LMMEADAK_01637 1.4e-263 fliF N The M ring may be actively involved in energy transduction
LMMEADAK_01638 1.3e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LMMEADAK_01639 3.7e-89 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
LMMEADAK_01640 2.7e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
LMMEADAK_01641 4.5e-71 fliJ N Flagellar biosynthesis chaperone
LMMEADAK_01642 4.4e-48 ylxF S MgtE intracellular N domain
LMMEADAK_01643 1.6e-204 fliK N Flagellar hook-length control protein
LMMEADAK_01644 6.9e-72 flgD N Flagellar basal body rod modification protein
LMMEADAK_01645 4e-139 flgG N Flagellar basal body rod
LMMEADAK_01646 7.8e-57 fliL N Controls the rotational direction of flagella during chemotaxis
LMMEADAK_01647 5.4e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
LMMEADAK_01648 8e-189 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LMMEADAK_01649 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
LMMEADAK_01650 1.3e-111 fliZ N Flagellar biosynthesis protein, FliO
LMMEADAK_01651 7.4e-110 fliP N Plays a role in the flagellum-specific transport system
LMMEADAK_01652 2e-37 fliQ N Role in flagellar biosynthesis
LMMEADAK_01653 4e-131 fliR N Flagellar biosynthetic protein FliR
LMMEADAK_01654 2.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LMMEADAK_01655 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LMMEADAK_01656 1e-193 flhF N Flagellar biosynthesis regulator FlhF
LMMEADAK_01657 2.3e-154 flhG D Belongs to the ParA family
LMMEADAK_01658 3.8e-193 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
LMMEADAK_01659 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
LMMEADAK_01660 8.8e-81 cheW NT COG0835 Chemotaxis signal transduction protein
LMMEADAK_01661 1.6e-109 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
LMMEADAK_01662 5.1e-87 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
LMMEADAK_01663 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LMMEADAK_01664 4e-54 ylxL
LMMEADAK_01665 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
LMMEADAK_01666 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LMMEADAK_01667 9.4e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LMMEADAK_01668 1.9e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LMMEADAK_01669 2.2e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LMMEADAK_01670 6.9e-139 cdsA 2.7.7.41 S Belongs to the CDS family
LMMEADAK_01671 2.5e-214 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
LMMEADAK_01672 1.5e-233 rasP M zinc metalloprotease
LMMEADAK_01673 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LMMEADAK_01674 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LMMEADAK_01675 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
LMMEADAK_01676 5.4e-206 nusA K Participates in both transcription termination and antitermination
LMMEADAK_01677 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
LMMEADAK_01678 1.8e-47 ylxQ J ribosomal protein
LMMEADAK_01679 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LMMEADAK_01680 3.9e-44 ylxP S protein conserved in bacteria
LMMEADAK_01681 3.3e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LMMEADAK_01682 3.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LMMEADAK_01683 3.5e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LMMEADAK_01684 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LMMEADAK_01685 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LMMEADAK_01686 8e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
LMMEADAK_01687 3e-234 pepR S Belongs to the peptidase M16 family
LMMEADAK_01688 2.6e-42 ymxH S YlmC YmxH family
LMMEADAK_01689 3.6e-160 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
LMMEADAK_01690 2e-106 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
LMMEADAK_01691 2.6e-194 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LMMEADAK_01692 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LMMEADAK_01693 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LMMEADAK_01694 1.2e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LMMEADAK_01695 4.5e-129 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
LMMEADAK_01696 6.3e-31 S YlzJ-like protein
LMMEADAK_01697 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LMMEADAK_01698 1.8e-133 ymfC K Transcriptional regulator
LMMEADAK_01699 2.4e-229 ymfD EGP Major facilitator Superfamily
LMMEADAK_01700 6.2e-76 K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_01701 0.0 ydgH S drug exporters of the RND superfamily
LMMEADAK_01702 1.2e-238 ymfF S Peptidase M16
LMMEADAK_01703 1.7e-243 ymfH S zinc protease
LMMEADAK_01704 4.6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
LMMEADAK_01705 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
LMMEADAK_01706 3.5e-143 ymfK S Protein of unknown function (DUF3388)
LMMEADAK_01707 4.2e-124 ymfM S protein conserved in bacteria
LMMEADAK_01708 3.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LMMEADAK_01709 3.8e-232 cinA 3.5.1.42 S Belongs to the CinA family
LMMEADAK_01710 6.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LMMEADAK_01711 1.3e-194 pbpX V Beta-lactamase
LMMEADAK_01712 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
LMMEADAK_01713 4.9e-153 ymdB S protein conserved in bacteria
LMMEADAK_01714 1.2e-36 spoVS S Stage V sporulation protein S
LMMEADAK_01715 1.5e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
LMMEADAK_01716 2.3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LMMEADAK_01717 2.2e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LMMEADAK_01718 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LMMEADAK_01719 1.7e-88 cotE S Spore coat protein
LMMEADAK_01720 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LMMEADAK_01721 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LMMEADAK_01722 1.4e-137 L Belongs to the 'phage' integrase family
LMMEADAK_01723 4.6e-46
LMMEADAK_01725 2.6e-23 K Helix-turn-helix XRE-family like proteins
LMMEADAK_01729 1.9e-86 ybl78 L Conserved phage C-terminus (Phg_2220_C)
LMMEADAK_01730 2.9e-50 dnaC L DNA replication protein
LMMEADAK_01732 5.8e-28
LMMEADAK_01736 3.6e-15 yqaO S Phage-like element PBSX protein XtrA
LMMEADAK_01741 1.8e-57
LMMEADAK_01743 4.7e-51 S dUTPase
LMMEADAK_01746 6.8e-08 S YopX protein
LMMEADAK_01750 4e-48
LMMEADAK_01752 7.4e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
LMMEADAK_01753 2.2e-72 L Phage integrase family
LMMEADAK_01755 2.4e-91 S AAA ATPase domain
LMMEADAK_01756 2.7e-14
LMMEADAK_01757 1.1e-79 L phage terminase small subunit
LMMEADAK_01758 4.4e-308 S Terminase
LMMEADAK_01759 1.2e-169 S Phage portal protein
LMMEADAK_01760 6.6e-84 S peptidase activity
LMMEADAK_01761 1.4e-152 gp36 S capsid protein
LMMEADAK_01762 8.7e-24
LMMEADAK_01763 1.1e-39 S Phage gp6-like head-tail connector protein
LMMEADAK_01764 2.9e-40 S Phage head-tail joining protein
LMMEADAK_01765 2.6e-49 S Bacteriophage HK97-gp10, putative tail-component
LMMEADAK_01767 2e-77 S Phage tail tube protein
LMMEADAK_01769 0.0 D phage tail tape measure protein
LMMEADAK_01770 3e-100 S Phage tail protein
LMMEADAK_01771 1.4e-229 NU Prophage endopeptidase tail
LMMEADAK_01772 0.0 M Pectate lyase superfamily protein
LMMEADAK_01773 2.6e-135 S Domain of unknown function (DUF2479)
LMMEADAK_01776 1.1e-27 bhlA S BhlA holin family
LMMEADAK_01777 3.3e-29 xhlB S SPP1 phage holin
LMMEADAK_01778 3e-70 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LMMEADAK_01779 6.4e-16 S Membrane
LMMEADAK_01780 5.2e-28
LMMEADAK_01781 2.9e-174 A Pre-toxin TG
LMMEADAK_01784 5.7e-129 pksB 3.1.2.6 S Polyketide biosynthesis
LMMEADAK_01785 9.8e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LMMEADAK_01786 9.6e-183 pksD Q Acyl transferase domain
LMMEADAK_01787 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LMMEADAK_01788 2.9e-35 acpK IQ Phosphopantetheine attachment site
LMMEADAK_01789 2.8e-243 pksG 2.3.3.10 I synthase
LMMEADAK_01790 1.4e-144 pksH 4.2.1.18 I enoyl-CoA hydratase
LMMEADAK_01791 2.9e-139 pksI I Belongs to the enoyl-CoA hydratase isomerase family
LMMEADAK_01792 0.0 rhiB IQ polyketide synthase
LMMEADAK_01793 0.0 Q Polyketide synthase of type I
LMMEADAK_01794 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
LMMEADAK_01795 0.0 dhbF IQ polyketide synthase
LMMEADAK_01796 0.0 pks13 HQ Beta-ketoacyl synthase
LMMEADAK_01797 1.4e-231 cypA C Cytochrome P450
LMMEADAK_01798 6.4e-78 nucB M Deoxyribonuclease NucA/NucB
LMMEADAK_01799 3.6e-118 yoaK S Membrane
LMMEADAK_01800 4.1e-62 ymzB
LMMEADAK_01801 8.9e-256 aprX O Belongs to the peptidase S8 family
LMMEADAK_01803 1.4e-127 ymaC S Replication protein
LMMEADAK_01804 3.9e-78 ymaD O redox protein, regulator of disulfide bond formation
LMMEADAK_01805 5.2e-54 ebrB P Small Multidrug Resistance protein
LMMEADAK_01806 3.1e-48 ebrA P Small Multidrug Resistance protein
LMMEADAK_01808 1.4e-47 ymaF S YmaF family
LMMEADAK_01809 8.7e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LMMEADAK_01810 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
LMMEADAK_01811 5.5e-43
LMMEADAK_01812 1.8e-20 ymzA
LMMEADAK_01813 1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
LMMEADAK_01814 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LMMEADAK_01815 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LMMEADAK_01816 9e-110 ymaB S MutT family
LMMEADAK_01817 1.3e-110 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LMMEADAK_01818 1.3e-176 spoVK O stage V sporulation protein K
LMMEADAK_01819 4.7e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LMMEADAK_01820 3.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
LMMEADAK_01821 4.3e-68 glnR K transcriptional
LMMEADAK_01822 1.9e-261 glnA 6.3.1.2 E glutamine synthetase
LMMEADAK_01823 3.7e-60
LMMEADAK_01825 1.8e-251 xynT G MFS/sugar transport protein
LMMEADAK_01826 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
LMMEADAK_01827 2.7e-216 xylR GK ROK family
LMMEADAK_01828 1.6e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
LMMEADAK_01829 7.6e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.189 G xylulose kinase
LMMEADAK_01830 1e-240 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LMMEADAK_01831 2.3e-237 pps 2.7.9.2 GT phosphoenolpyruvate synthase
LMMEADAK_01834 5.4e-17
LMMEADAK_01835 1.7e-54 dinB S DinB family
LMMEADAK_01836 9.7e-186 adhP 1.1.1.1 C alcohol dehydrogenase
LMMEADAK_01838 3.1e-89 yoaP 3.1.3.18 K YoaP-like
LMMEADAK_01839 1.4e-41 yoaP 3.1.3.18 K YoaP-like
LMMEADAK_01840 3.2e-96 J Acetyltransferase (GNAT) domain
LMMEADAK_01841 1.4e-36
LMMEADAK_01843 2e-117 ynaE S Domain of unknown function (DUF3885)
LMMEADAK_01844 5.4e-203 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LMMEADAK_01845 1.2e-117 AA10,CBM73 S Pfam:Chitin_bind_3
LMMEADAK_01847 3.4e-65 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
LMMEADAK_01848 6.6e-93 yvgO
LMMEADAK_01850 0.0 yobO M Pectate lyase superfamily protein
LMMEADAK_01851 2.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
LMMEADAK_01852 7.1e-147 yndL S Replication protein
LMMEADAK_01853 1.6e-07
LMMEADAK_01854 1.2e-138 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
LMMEADAK_01855 2.4e-72 yndM S Protein of unknown function (DUF2512)
LMMEADAK_01856 4.6e-12 yoaW
LMMEADAK_01857 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LMMEADAK_01858 6.2e-51 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
LMMEADAK_01859 1.3e-111 yneB L resolvase
LMMEADAK_01860 9.8e-33 ynzC S UPF0291 protein
LMMEADAK_01861 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LMMEADAK_01862 8.3e-81 yneE S Sporulation inhibitor of replication protein sirA
LMMEADAK_01863 2.3e-28 yneF S UPF0154 protein
LMMEADAK_01864 3.1e-23 ynzD S Spo0E like sporulation regulatory protein
LMMEADAK_01865 1.7e-125 ccdA O cytochrome c biogenesis protein
LMMEADAK_01866 1e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
LMMEADAK_01867 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
LMMEADAK_01868 8.5e-75 yneK S Protein of unknown function (DUF2621)
LMMEADAK_01869 3.2e-62 hspX O Spore coat protein
LMMEADAK_01870 2.3e-19 sspP S Belongs to the SspP family
LMMEADAK_01871 7.5e-15 sspO S Belongs to the SspO family
LMMEADAK_01872 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LMMEADAK_01873 3.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LMMEADAK_01875 2.7e-33 tlp S Belongs to the Tlp family
LMMEADAK_01876 8.3e-75 yneP S Thioesterase-like superfamily
LMMEADAK_01877 7.5e-54 yneQ
LMMEADAK_01878 1.3e-50 yneR S Belongs to the HesB IscA family
LMMEADAK_01879 1.4e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LMMEADAK_01880 1.5e-68 yccU S CoA-binding protein
LMMEADAK_01881 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LMMEADAK_01882 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LMMEADAK_01883 4.6e-13
LMMEADAK_01884 5.1e-41 ynfC
LMMEADAK_01885 4.6e-250 agcS E Sodium alanine symporter
LMMEADAK_01886 4.7e-182 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
LMMEADAK_01887 6.3e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
LMMEADAK_01888 2e-112 eda 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
LMMEADAK_01889 1.2e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
LMMEADAK_01890 9.2e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LMMEADAK_01891 5.4e-181 kdgR_1 K transcriptional
LMMEADAK_01892 8.6e-224 exuT G Sugar (and other) transporter
LMMEADAK_01893 1.3e-156 yndG S DoxX-like family
LMMEADAK_01894 1.1e-78 yndH S Domain of unknown function (DUF4166)
LMMEADAK_01895 1.7e-304 yndJ S YndJ-like protein
LMMEADAK_01896 1.7e-86 S Protein of unknown function (DUF1430)
LMMEADAK_01897 2.6e-64 V ABC transporter
LMMEADAK_01899 1e-212 S Platelet-activating factor acetylhydrolase, isoform II
LMMEADAK_01900 2.8e-290 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
LMMEADAK_01901 1.3e-51 S Domain of unknown function (DUF4870)
LMMEADAK_01902 3.7e-236 T PhoQ Sensor
LMMEADAK_01903 8.9e-130 T Transcriptional regulatory protein, C terminal
LMMEADAK_01904 2.2e-251 xynC 3.2.1.136 GH5 G Glycosyl hydrolase family 30 beta sandwich domain
LMMEADAK_01905 5.8e-291 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
LMMEADAK_01906 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_01907 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_01908 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_01909 4.4e-222 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LMMEADAK_01910 6.9e-139 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LMMEADAK_01911 7.1e-121 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LMMEADAK_01912 4.4e-126 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LMMEADAK_01913 6.9e-254 yxjC EG COG2610 H gluconate symporter and related permeases
LMMEADAK_01914 1.8e-223 bioI 1.14.14.46 C Cytochrome P450
LMMEADAK_01915 2.2e-193 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LMMEADAK_01916 4.4e-129 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LMMEADAK_01917 3e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
LMMEADAK_01918 1.2e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
LMMEADAK_01919 9.7e-146 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
LMMEADAK_01920 1.1e-71 yngA S membrane
LMMEADAK_01921 1.9e-161 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LMMEADAK_01922 3.2e-104 yngC S SNARE associated Golgi protein
LMMEADAK_01923 2.4e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LMMEADAK_01924 1.7e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LMMEADAK_01925 1.6e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
LMMEADAK_01926 2.4e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
LMMEADAK_01927 5.5e-253 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
LMMEADAK_01928 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LMMEADAK_01929 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
LMMEADAK_01930 4.5e-304 yngK T Glycosyl hydrolase-like 10
LMMEADAK_01931 4.1e-65 yngL S Protein of unknown function (DUF1360)
LMMEADAK_01932 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
LMMEADAK_01933 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_01934 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_01935 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_01936 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_01937 1.4e-270 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
LMMEADAK_01938 6.9e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
LMMEADAK_01939 1.1e-245 yoeA V MATE efflux family protein
LMMEADAK_01940 5.9e-97 yoeB S IseA DL-endopeptidase inhibitor
LMMEADAK_01942 1e-96 L Integrase
LMMEADAK_01943 1.8e-34 yoeD G Helix-turn-helix domain
LMMEADAK_01944 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LMMEADAK_01945 1.2e-200 ybcL EGP Major facilitator Superfamily
LMMEADAK_01946 1.8e-50 ybzH K Helix-turn-helix domain
LMMEADAK_01947 2.4e-14 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LMMEADAK_01948 4e-156 gltR1 K Transcriptional regulator
LMMEADAK_01949 3.5e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LMMEADAK_01950 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
LMMEADAK_01951 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
LMMEADAK_01952 3.9e-146 gltC K Transcriptional regulator
LMMEADAK_01953 2.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LMMEADAK_01954 8.2e-140 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LMMEADAK_01955 3.9e-60 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
LMMEADAK_01956 5.2e-125 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LMMEADAK_01957 2.1e-43 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LMMEADAK_01958 6e-140 yoxB
LMMEADAK_01959 1.5e-204 yoaB EGP Major facilitator Superfamily
LMMEADAK_01960 1.5e-275 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
LMMEADAK_01961 1.3e-193 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LMMEADAK_01962 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LMMEADAK_01963 1.1e-25 yoaF
LMMEADAK_01965 3.9e-99 hpr K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_01966 9.6e-43
LMMEADAK_01967 5.3e-83 S SMI1-KNR4 cell-wall
LMMEADAK_01968 1.6e-215 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LMMEADAK_01969 3e-73 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LMMEADAK_01970 1.9e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
LMMEADAK_01971 7.8e-134 yobQ K helix_turn_helix, arabinose operon control protein
LMMEADAK_01972 7.5e-95 yobS K Transcriptional regulator
LMMEADAK_01973 1.9e-135 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
LMMEADAK_01974 1.9e-92 yobW
LMMEADAK_01975 3.4e-55 czrA K transcriptional
LMMEADAK_01976 5.5e-121 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
LMMEADAK_01977 4.7e-91 yozB S membrane
LMMEADAK_01978 1.1e-139 yocB J Protein required for attachment to host cells
LMMEADAK_01979 1.9e-94 yocC
LMMEADAK_01980 9.9e-188 yocD 3.4.17.13 V peptidase S66
LMMEADAK_01982 2.8e-112 yocH CBM50 M COG1388 FOG LysM repeat
LMMEADAK_01983 0.0 recQ 3.6.4.12 L DNA helicase
LMMEADAK_01984 2.8e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LMMEADAK_01986 2.5e-54 dksA T general stress protein
LMMEADAK_01987 4.5e-10 yocL
LMMEADAK_01988 1.7e-08
LMMEADAK_01989 2e-88 yocM O Belongs to the small heat shock protein (HSP20) family
LMMEADAK_01990 3.8e-44 yozN
LMMEADAK_01991 8.5e-37 yocN
LMMEADAK_01992 9.3e-56 yozO S Bacterial PH domain
LMMEADAK_01994 1.6e-31 yozC
LMMEADAK_01995 1.7e-287 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
LMMEADAK_01996 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
LMMEADAK_01997 1.2e-165 sodA 1.15.1.1 P Superoxide dismutase
LMMEADAK_01998 1.9e-234 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
LMMEADAK_01999 3.5e-161 yocS S -transporter
LMMEADAK_02000 2.6e-140 S Metallo-beta-lactamase superfamily
LMMEADAK_02001 2.7e-182 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
LMMEADAK_02002 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
LMMEADAK_02003 0.0 yojO P Von Willebrand factor
LMMEADAK_02004 1e-162 yojN S ATPase family associated with various cellular activities (AAA)
LMMEADAK_02005 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LMMEADAK_02006 1.6e-227 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
LMMEADAK_02007 3e-226 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
LMMEADAK_02008 2.2e-111 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LMMEADAK_02010 3.3e-242 norM V Multidrug efflux pump
LMMEADAK_02011 6.5e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LMMEADAK_02012 7.4e-126 yojG S deacetylase
LMMEADAK_02013 9.7e-61 yojF S Protein of unknown function (DUF1806)
LMMEADAK_02014 4.9e-23
LMMEADAK_02015 7.8e-163 rarD S -transporter
LMMEADAK_02016 1.1e-80 yozR S COG0071 Molecular chaperone (small heat shock protein)
LMMEADAK_02018 2.3e-66 yodA S tautomerase
LMMEADAK_02019 3.5e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
LMMEADAK_02020 1.4e-56 yodB K transcriptional
LMMEADAK_02021 4.5e-106 yodC C nitroreductase
LMMEADAK_02022 6.1e-111 mhqD S Carboxylesterase
LMMEADAK_02023 1.1e-175 yodE E COG0346 Lactoylglutathione lyase and related lyases
LMMEADAK_02024 1.4e-19 S Protein of unknown function (DUF3311)
LMMEADAK_02025 3.5e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LMMEADAK_02027 6.1e-255 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
LMMEADAK_02028 6.3e-128 yodH Q Methyltransferase
LMMEADAK_02029 1.2e-33 yodI
LMMEADAK_02030 1.8e-145 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LMMEADAK_02031 3.5e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
LMMEADAK_02033 3.3e-55 yodL S YodL-like
LMMEADAK_02034 5.6e-104 yodM 3.6.1.27 I Acid phosphatase homologues
LMMEADAK_02035 6.2e-24 yozD S YozD-like protein
LMMEADAK_02037 4.9e-125 yodN
LMMEADAK_02038 4.1e-36 yozE S Belongs to the UPF0346 family
LMMEADAK_02039 3.2e-46 yokU S YokU-like protein, putative antitoxin
LMMEADAK_02040 2.7e-279 kamA 5.4.3.2 E lysine 2,3-aminomutase
LMMEADAK_02041 1.2e-157 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
LMMEADAK_02042 1.5e-255 yodQ 3.5.1.16 E Acetylornithine deacetylase
LMMEADAK_02043 8e-123 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
LMMEADAK_02044 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LMMEADAK_02045 1.2e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LMMEADAK_02046 3e-62 yosT L Bacterial transcription activator, effector binding domain
LMMEADAK_02048 1.3e-145 yiiD K acetyltransferase
LMMEADAK_02049 2.5e-247 cgeD M maturation of the outermost layer of the spore
LMMEADAK_02050 2.5e-41 cgeC
LMMEADAK_02051 1.6e-52 cgeA
LMMEADAK_02052 1e-181 cgeB S Spore maturation protein
LMMEADAK_02053 4.7e-221 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
LMMEADAK_02054 7.9e-73 4.2.1.115 GM Polysaccharide biosynthesis protein
LMMEADAK_02060 5.9e-78
LMMEADAK_02061 2.6e-08
LMMEADAK_02065 9.8e-30 yoqH M LysM domain
LMMEADAK_02067 5.3e-193 S aspartate phosphatase
LMMEADAK_02069 4.1e-160 3.4.24.40 S amine dehydrogenase activity
LMMEADAK_02072 8.3e-52 S SMI1-KNR4 cell-wall
LMMEADAK_02073 4.7e-292 yobL L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
LMMEADAK_02074 1.5e-90 yokH G SMI1 / KNR4 family
LMMEADAK_02075 1.3e-140 S Protein of unknown function (DUF4238)
LMMEADAK_02076 2.7e-18 yokF 3.1.31.1 L RNA catabolic process
LMMEADAK_02079 8.7e-309 yokA L Recombinase
LMMEADAK_02080 1.4e-104 4.2.1.115 GM Polysaccharide biosynthesis protein
LMMEADAK_02081 1.2e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
LMMEADAK_02082 5.4e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LMMEADAK_02083 4.7e-67 ypoP K transcriptional
LMMEADAK_02084 5.5e-98 ypmS S protein conserved in bacteria
LMMEADAK_02085 8.9e-136 ypmR E GDSL-like Lipase/Acylhydrolase
LMMEADAK_02086 1.1e-106 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
LMMEADAK_02087 2.6e-39 ypmP S Protein of unknown function (DUF2535)
LMMEADAK_02088 4.8e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LMMEADAK_02089 4.2e-178 pspF K Transcriptional regulator
LMMEADAK_02090 9.3e-110 hlyIII S protein, Hemolysin III
LMMEADAK_02091 4.6e-114 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
LMMEADAK_02092 1.3e-90 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LMMEADAK_02093 2.5e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LMMEADAK_02094 2.7e-114 ypjP S YpjP-like protein
LMMEADAK_02095 1.3e-129 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
LMMEADAK_02096 1e-75 yphP S Belongs to the UPF0403 family
LMMEADAK_02097 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LMMEADAK_02098 2.8e-157 ypgR C COG0694 Thioredoxin-like proteins and domains
LMMEADAK_02099 2.8e-100 ypgQ S phosphohydrolase
LMMEADAK_02100 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
LMMEADAK_02101 5.6e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LMMEADAK_02102 2.5e-214 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
LMMEADAK_02103 1e-30 cspD K Cold-shock protein
LMMEADAK_02104 3.3e-12 degR
LMMEADAK_02105 1.2e-36 S Protein of unknown function (DUF2564)
LMMEADAK_02106 3.7e-27 ypeQ S Zinc-finger
LMMEADAK_02107 6.3e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
LMMEADAK_02108 3.1e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LMMEADAK_02109 3e-66 rnhA 3.1.26.4 L Ribonuclease
LMMEADAK_02111 4.1e-164 polA 2.7.7.7 L 5'3' exonuclease
LMMEADAK_02113 3.5e-39 ypbS S Protein of unknown function (DUF2533)
LMMEADAK_02114 0.0 ypbR S Dynamin family
LMMEADAK_02115 7.2e-89 ypbQ S protein conserved in bacteria
LMMEADAK_02116 1.8e-206 bcsA Q Naringenin-chalcone synthase
LMMEADAK_02117 1.4e-107 J Acetyltransferase (GNAT) domain
LMMEADAK_02118 3.1e-50 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
LMMEADAK_02119 8.7e-09 S Bacillus cereus group antimicrobial protein
LMMEADAK_02120 2.7e-34 ydfR S Protein of unknown function (DUF421)
LMMEADAK_02121 9.6e-39 ydfR S Protein of unknown function (DUF421)
LMMEADAK_02122 7e-101 yrdC 3.5.1.19 Q Isochorismatase family
LMMEADAK_02124 1.3e-235 pbuX F xanthine
LMMEADAK_02125 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LMMEADAK_02126 8.7e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LMMEADAK_02127 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
LMMEADAK_02129 6.6e-22 S YpzG-like protein
LMMEADAK_02130 4.9e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LMMEADAK_02131 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LMMEADAK_02132 1.8e-98 ypsA S Belongs to the UPF0398 family
LMMEADAK_02133 9.9e-33 cotD S Inner spore coat protein D
LMMEADAK_02134 2.1e-235 yprB L RNase_H superfamily
LMMEADAK_02135 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
LMMEADAK_02136 2.7e-88 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
LMMEADAK_02137 1.7e-72 hspX O Belongs to the small heat shock protein (HSP20) family
LMMEADAK_02138 4.8e-49 yppG S YppG-like protein
LMMEADAK_02140 1.3e-10 yppE S Bacterial domain of unknown function (DUF1798)
LMMEADAK_02143 2.6e-188 yppC S Protein of unknown function (DUF2515)
LMMEADAK_02144 2.7e-111 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LMMEADAK_02145 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LMMEADAK_02146 3.7e-90 ypoC
LMMEADAK_02147 1.1e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LMMEADAK_02148 6.8e-130 dnaD L DNA replication protein DnaD
LMMEADAK_02149 2e-252 asnS 6.1.1.22 J asparaginyl-tRNA
LMMEADAK_02150 1.7e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LMMEADAK_02151 4e-81 ypmB S protein conserved in bacteria
LMMEADAK_02152 6.7e-23 ypmA S Protein of unknown function (DUF4264)
LMMEADAK_02153 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LMMEADAK_02154 6e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LMMEADAK_02155 5.5e-158 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LMMEADAK_02156 7e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
LMMEADAK_02157 1.1e-181 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LMMEADAK_02158 1.5e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LMMEADAK_02159 4.8e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
LMMEADAK_02160 1.3e-131 bshB1 S proteins, LmbE homologs
LMMEADAK_02161 1.4e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
LMMEADAK_02162 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LMMEADAK_02163 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
LMMEADAK_02164 3.6e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
LMMEADAK_02165 4.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
LMMEADAK_02166 4.7e-140 ypjB S sporulation protein
LMMEADAK_02167 2.6e-106 ypjA S membrane
LMMEADAK_02168 3.9e-147 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
LMMEADAK_02169 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
LMMEADAK_02170 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
LMMEADAK_02171 2.9e-78 ypiF S Protein of unknown function (DUF2487)
LMMEADAK_02172 2.1e-99 ypiB S Belongs to the UPF0302 family
LMMEADAK_02173 1e-232 S COG0457 FOG TPR repeat
LMMEADAK_02174 1.2e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LMMEADAK_02175 5.4e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LMMEADAK_02176 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LMMEADAK_02177 8.5e-145 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
LMMEADAK_02178 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LMMEADAK_02179 5.5e-118 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
LMMEADAK_02180 3e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
LMMEADAK_02181 1.2e-159 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LMMEADAK_02182 5.2e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LMMEADAK_02183 2.4e-60 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
LMMEADAK_02184 7.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LMMEADAK_02185 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LMMEADAK_02186 6.5e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
LMMEADAK_02187 2e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LMMEADAK_02188 1.6e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LMMEADAK_02189 1.2e-131 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
LMMEADAK_02190 6.2e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
LMMEADAK_02191 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
LMMEADAK_02192 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
LMMEADAK_02193 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LMMEADAK_02194 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LMMEADAK_02195 4.8e-134 yphF
LMMEADAK_02196 3.3e-16 yphE S Protein of unknown function (DUF2768)
LMMEADAK_02197 5.1e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LMMEADAK_02198 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LMMEADAK_02199 1.4e-104 yphA
LMMEADAK_02200 4.7e-08 S YpzI-like protein
LMMEADAK_02201 1.5e-186 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LMMEADAK_02202 5.6e-206 rpsA 1.17.7.4 J Ribosomal protein S1
LMMEADAK_02203 2.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LMMEADAK_02204 1.4e-12 S Family of unknown function (DUF5359)
LMMEADAK_02205 2.2e-61 ypfA M Flagellar protein YcgR
LMMEADAK_02206 7.1e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
LMMEADAK_02207 3.7e-154 sleB 3.5.1.28 M Spore cortex-lytic enzyme
LMMEADAK_02208 1.2e-120 prsW S Involved in the degradation of specific anti-sigma factors
LMMEADAK_02209 2.6e-188 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
LMMEADAK_02210 1.4e-245 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LMMEADAK_02211 2e-106 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
LMMEADAK_02212 7.3e-149 ypbG S Calcineurin-like phosphoesterase superfamily domain
LMMEADAK_02213 5.7e-85 ypbF S Protein of unknown function (DUF2663)
LMMEADAK_02214 1.2e-76 ypbE M Lysin motif
LMMEADAK_02215 3.2e-98 ypbD S metal-dependent membrane protease
LMMEADAK_02216 2.5e-272 recQ 3.6.4.12 L DNA helicase
LMMEADAK_02217 2.3e-198 ypbB 5.1.3.1 S protein conserved in bacteria
LMMEADAK_02218 3.6e-41 fer C Ferredoxin
LMMEADAK_02219 1.4e-93 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LMMEADAK_02220 2.8e-293 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LMMEADAK_02221 1.4e-198 rsiX
LMMEADAK_02222 9.1e-104 sigX K Belongs to the sigma-70 factor family. ECF subfamily
LMMEADAK_02223 0.0 resE 2.7.13.3 T Histidine kinase
LMMEADAK_02224 2.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_02225 1.9e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
LMMEADAK_02226 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
LMMEADAK_02227 4.3e-100 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
LMMEADAK_02228 7.6e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LMMEADAK_02229 1.7e-88 spmB S Spore maturation protein
LMMEADAK_02230 2e-103 spmA S Spore maturation protein
LMMEADAK_02231 5e-215 dacB 3.4.16.4 M Belongs to the peptidase S11 family
LMMEADAK_02232 1.3e-93 ypuI S Protein of unknown function (DUF3907)
LMMEADAK_02233 7.8e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LMMEADAK_02234 2.3e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LMMEADAK_02236 3.8e-93 ypuF S Domain of unknown function (DUF309)
LMMEADAK_02237 3.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LMMEADAK_02238 2.5e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
LMMEADAK_02239 3.7e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LMMEADAK_02240 1e-111 ribE 2.5.1.9 H Riboflavin synthase
LMMEADAK_02241 7.3e-211 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LMMEADAK_02242 1.7e-49 ypuD
LMMEADAK_02243 6.9e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
LMMEADAK_02244 8.2e-82 ccdC1 O Protein of unknown function (DUF1453)
LMMEADAK_02245 1.2e-44 L COG2963 Transposase and inactivated derivatives
LMMEADAK_02246 5.7e-141 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_02247 4.4e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LMMEADAK_02248 5.1e-154 ypuA S Secreted protein
LMMEADAK_02249 1e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LMMEADAK_02250 1.4e-270 spoVAF EG Stage V sporulation protein AF
LMMEADAK_02251 1.8e-110 spoVAEA S stage V sporulation protein
LMMEADAK_02252 3.8e-57 spoVAEB S stage V sporulation protein
LMMEADAK_02253 5e-190 spoVAD I Stage V sporulation protein AD
LMMEADAK_02254 1.3e-78 spoVAC S stage V sporulation protein AC
LMMEADAK_02255 3.9e-60 spoVAB S Stage V sporulation protein AB
LMMEADAK_02256 3.7e-111 spoVAA S Stage V sporulation protein AA
LMMEADAK_02257 1e-134 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LMMEADAK_02258 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
LMMEADAK_02259 7.8e-58 spoIIAA T Belongs to the anti-sigma-factor antagonist family
LMMEADAK_02260 2.2e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
LMMEADAK_02261 6.4e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LMMEADAK_02262 2.3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LMMEADAK_02263 1.7e-165 xerD L recombinase XerD
LMMEADAK_02264 6.4e-37 S Protein of unknown function (DUF4227)
LMMEADAK_02265 1.9e-80 fur P Belongs to the Fur family
LMMEADAK_02266 5.5e-110 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
LMMEADAK_02268 1.7e-34 yqkK
LMMEADAK_02269 5.7e-22
LMMEADAK_02270 7.7e-244 mleA 1.1.1.38 C malic enzyme
LMMEADAK_02271 2e-242 mleN C Na H antiporter
LMMEADAK_02272 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
LMMEADAK_02273 8.5e-187 ansA 3.5.1.1 EJ L-asparaginase
LMMEADAK_02274 7.8e-58 ansR K Transcriptional regulator
LMMEADAK_02275 1.1e-220 yqxK 3.6.4.12 L DNA helicase
LMMEADAK_02276 1.6e-94 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
LMMEADAK_02278 3.3e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
LMMEADAK_02280 2.8e-176 yqkD S COG1073 Hydrolases of the alpha beta superfamily
LMMEADAK_02281 3.2e-39 yqkC S Protein of unknown function (DUF2552)
LMMEADAK_02282 7.7e-61 yqkB S Belongs to the HesB IscA family
LMMEADAK_02283 1.5e-175 yqkA K GrpB protein
LMMEADAK_02284 7.3e-61 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
LMMEADAK_02285 3.9e-89 yqjY K acetyltransferase
LMMEADAK_02286 7.2e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LMMEADAK_02287 7.6e-58 S YolD-like protein
LMMEADAK_02289 6.9e-190 yueF S transporter activity
LMMEADAK_02291 1.1e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LMMEADAK_02292 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
LMMEADAK_02293 3.9e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
LMMEADAK_02294 6.5e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
LMMEADAK_02295 2.4e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
LMMEADAK_02296 4.7e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LMMEADAK_02297 4e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
LMMEADAK_02298 2.9e-240 pksG 2.3.3.10 I synthase
LMMEADAK_02299 6.8e-220 eryK 1.14.13.154 C Cytochrome P450
LMMEADAK_02300 0.0 pks13 1.6.5.5 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
LMMEADAK_02301 0.0 Q Polyketide synthase of type I
LMMEADAK_02302 0.0 pfaA Q Polyketide synthase of type I
LMMEADAK_02303 0.0 pksJ Q Polyketide synthase of type I
LMMEADAK_02304 0.0 Q Polyketide synthase of type I
LMMEADAK_02305 0.0 1.1.1.320 Q Polyketide synthase of type I
LMMEADAK_02306 0.0 pksJ Q Polyketide synthase of type I
LMMEADAK_02307 3.5e-129 IQ reductase
LMMEADAK_02308 7.7e-247 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LMMEADAK_02311 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
LMMEADAK_02312 1.6e-94 nusG K Participates in transcription elongation, termination and antitermination
LMMEADAK_02313 7.6e-163 K LysR substrate binding domain
LMMEADAK_02314 3.2e-50 S GlpM protein
LMMEADAK_02315 1.6e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
LMMEADAK_02316 1e-147 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LMMEADAK_02317 1.8e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LMMEADAK_02318 4.2e-172 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LMMEADAK_02319 6.1e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LMMEADAK_02320 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LMMEADAK_02321 3.9e-237 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LMMEADAK_02322 2.4e-25 yqzJ
LMMEADAK_02323 3.5e-149 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LMMEADAK_02324 4.7e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
LMMEADAK_02325 8.8e-292 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
LMMEADAK_02326 5.5e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
LMMEADAK_02328 1.4e-95 yqjB S protein conserved in bacteria
LMMEADAK_02329 6.3e-171 yqjA S Putative aromatic acid exporter C-terminal domain
LMMEADAK_02330 2.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LMMEADAK_02331 3.8e-106 artQ E COG0765 ABC-type amino acid transport system, permease component
LMMEADAK_02332 3.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
LMMEADAK_02333 5.8e-101 L Integrase core domain
LMMEADAK_02334 1.7e-40 L COG2963 Transposase and inactivated derivatives
LMMEADAK_02335 1e-75 yqiW S Belongs to the UPF0403 family
LMMEADAK_02336 6.6e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LMMEADAK_02337 8.8e-205 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LMMEADAK_02338 4.6e-185 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LMMEADAK_02339 3e-163 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
LMMEADAK_02340 7e-267 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
LMMEADAK_02341 9.8e-208 buk 2.7.2.7 C Belongs to the acetokinase family
LMMEADAK_02342 1.5e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
LMMEADAK_02343 4.3e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
LMMEADAK_02344 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
LMMEADAK_02345 3.2e-34 yqzF S Protein of unknown function (DUF2627)
LMMEADAK_02346 1.6e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LMMEADAK_02347 3.4e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
LMMEADAK_02348 5.7e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
LMMEADAK_02349 5.5e-206 mmgC I acyl-CoA dehydrogenase
LMMEADAK_02350 6.9e-153 hbdA 1.1.1.157 I Dehydrogenase
LMMEADAK_02351 5.7e-214 mmgA 2.3.1.9 I Belongs to the thiolase family
LMMEADAK_02352 1.3e-134 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
LMMEADAK_02353 1.4e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
LMMEADAK_02354 3.2e-17
LMMEADAK_02355 1.5e-101 ytaF P Probably functions as a manganese efflux pump
LMMEADAK_02356 1.8e-113 K Protein of unknown function (DUF1232)
LMMEADAK_02358 1.4e-214 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
LMMEADAK_02361 2e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LMMEADAK_02362 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
LMMEADAK_02363 9.5e-239 rseP 3.4.21.116 M Stage IV sporulation protein B
LMMEADAK_02364 1.2e-305 recN L May be involved in recombinational repair of damaged DNA
LMMEADAK_02365 3.9e-78 argR K Regulates arginine biosynthesis genes
LMMEADAK_02366 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
LMMEADAK_02367 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LMMEADAK_02368 2.1e-160 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LMMEADAK_02369 2e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LMMEADAK_02370 3.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LMMEADAK_02371 4.3e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LMMEADAK_02372 1.1e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LMMEADAK_02373 8.1e-67 yqhY S protein conserved in bacteria
LMMEADAK_02374 1.2e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LMMEADAK_02375 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LMMEADAK_02376 2.5e-62 spoIIIAH S SpoIIIAH-like protein
LMMEADAK_02377 7.7e-118 spoIIIAG S stage III sporulation protein AG
LMMEADAK_02378 6.9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
LMMEADAK_02379 6.3e-200 spoIIIAE S stage III sporulation protein AE
LMMEADAK_02380 2.5e-41 spoIIIAD S Stage III sporulation protein AD
LMMEADAK_02381 7.6e-29 spoIIIAC S stage III sporulation protein AC
LMMEADAK_02382 1.7e-85 spoIIIAB S Stage III sporulation protein
LMMEADAK_02383 4.2e-172 spoIIIAA S stage III sporulation protein AA
LMMEADAK_02384 1.8e-36 yqhV S Protein of unknown function (DUF2619)
LMMEADAK_02385 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LMMEADAK_02386 3.2e-171 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
LMMEADAK_02387 3.7e-88 yqhR S Conserved membrane protein YqhR
LMMEADAK_02388 1e-173 yqhQ S Protein of unknown function (DUF1385)
LMMEADAK_02389 1.7e-61 yqhP
LMMEADAK_02390 1.1e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
LMMEADAK_02391 2.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
LMMEADAK_02392 5.7e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
LMMEADAK_02393 2.7e-64 yqhL P COG0607 Rhodanese-related sulfurtransferase
LMMEADAK_02394 9.8e-288 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LMMEADAK_02395 1e-251 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LMMEADAK_02396 2e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
LMMEADAK_02397 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LMMEADAK_02398 8.4e-153 yqhG S Bacterial protein YqhG of unknown function
LMMEADAK_02399 5.2e-23 sinI S Anti-repressor SinI
LMMEADAK_02400 7.8e-55 sinR K transcriptional
LMMEADAK_02401 3.3e-141 tasA S Cell division protein FtsN
LMMEADAK_02402 1e-70 sipW 3.4.21.89 U Signal peptidase
LMMEADAK_02403 4.7e-120 yqxM
LMMEADAK_02404 1.3e-54 yqzG S Protein of unknown function (DUF3889)
LMMEADAK_02405 2.3e-26 yqzE S YqzE-like protein
LMMEADAK_02406 2.9e-63 S ComG operon protein 7
LMMEADAK_02407 8.7e-66 comGF U Putative Competence protein ComGF
LMMEADAK_02408 5.8e-20 comGE
LMMEADAK_02409 6.2e-73 gspH NU Tfp pilus assembly protein FimT
LMMEADAK_02410 8.9e-50 comGC U Required for transformation and DNA binding
LMMEADAK_02411 1.1e-184 comGB NU COG1459 Type II secretory pathway, component PulF
LMMEADAK_02412 1.7e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LMMEADAK_02413 4.1e-186 corA P Mg2 transporter protein
LMMEADAK_02414 7.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
LMMEADAK_02415 1.6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
LMMEADAK_02417 9.2e-65 yqgZ 1.20.4.1 P Belongs to the ArsC family
LMMEADAK_02418 3.1e-37 yqgY S Protein of unknown function (DUF2626)
LMMEADAK_02419 8.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LMMEADAK_02420 5.4e-20 yqgW S Protein of unknown function (DUF2759)
LMMEADAK_02421 6.9e-50 yqgV S Thiamine-binding protein
LMMEADAK_02422 2e-199 yqgU
LMMEADAK_02423 7.9e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
LMMEADAK_02424 2.2e-179 glcK 2.7.1.2 G Glucokinase
LMMEADAK_02425 1.5e-212 nhaC C Na H antiporter
LMMEADAK_02426 4e-07 yqgO
LMMEADAK_02427 2.1e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LMMEADAK_02428 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LMMEADAK_02429 1.2e-50 yqzD
LMMEADAK_02430 3.7e-76 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LMMEADAK_02431 1.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LMMEADAK_02432 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LMMEADAK_02433 1.8e-156 pstA P Phosphate transport system permease
LMMEADAK_02434 1.4e-159 pstC P probably responsible for the translocation of the substrate across the membrane
LMMEADAK_02435 7.6e-158 pstS P Phosphate
LMMEADAK_02436 0.0 pbpA 3.4.16.4 M penicillin-binding protein
LMMEADAK_02437 2e-228 yqgE EGP Major facilitator superfamily
LMMEADAK_02438 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
LMMEADAK_02439 6e-77 yqgC S protein conserved in bacteria
LMMEADAK_02440 2.5e-130 yqgB S Protein of unknown function (DUF1189)
LMMEADAK_02441 5.3e-47 yqfZ M LysM domain
LMMEADAK_02442 3.1e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LMMEADAK_02443 2.3e-52 yqfX S membrane
LMMEADAK_02444 6.5e-110 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
LMMEADAK_02445 2.9e-72 zur P Belongs to the Fur family
LMMEADAK_02446 1.4e-156 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LMMEADAK_02447 7.9e-36 yqfT S Protein of unknown function (DUF2624)
LMMEADAK_02448 1.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LMMEADAK_02449 3e-240 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LMMEADAK_02450 1.3e-48 yqfQ S YqfQ-like protein
LMMEADAK_02451 2.5e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LMMEADAK_02452 4.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LMMEADAK_02453 8.4e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
LMMEADAK_02454 1.1e-62 cccA C COG2010 Cytochrome c, mono- and diheme variants
LMMEADAK_02455 2.4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LMMEADAK_02456 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LMMEADAK_02457 6.1e-88 yaiI S Belongs to the UPF0178 family
LMMEADAK_02458 2e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
LMMEADAK_02459 4.5e-112 ccpN K CBS domain
LMMEADAK_02460 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LMMEADAK_02461 5.1e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LMMEADAK_02462 1.2e-143 recO L Involved in DNA repair and RecF pathway recombination
LMMEADAK_02463 1.8e-16 S YqzL-like protein
LMMEADAK_02464 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LMMEADAK_02465 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LMMEADAK_02466 8.6e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LMMEADAK_02467 4.3e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LMMEADAK_02468 0.0 yqfF S membrane-associated HD superfamily hydrolase
LMMEADAK_02469 3.8e-176 phoH T Phosphate starvation-inducible protein PhoH
LMMEADAK_02470 6.8e-215 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
LMMEADAK_02471 9.3e-46 yqfC S sporulation protein YqfC
LMMEADAK_02472 3.4e-55 yqfB
LMMEADAK_02473 1.6e-121 yqfA S UPF0365 protein
LMMEADAK_02474 9.2e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
LMMEADAK_02475 1.2e-68 yqeY S Yqey-like protein
LMMEADAK_02476 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LMMEADAK_02477 2.7e-158 yqeW P COG1283 Na phosphate symporter
LMMEADAK_02478 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
LMMEADAK_02479 1.1e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LMMEADAK_02480 6e-174 prmA J Methylates ribosomal protein L11
LMMEADAK_02481 1.1e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LMMEADAK_02482 0.0 dnaK O Heat shock 70 kDa protein
LMMEADAK_02483 3.5e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LMMEADAK_02484 1.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LMMEADAK_02485 2.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
LMMEADAK_02486 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LMMEADAK_02487 3.8e-54 yqxA S Protein of unknown function (DUF3679)
LMMEADAK_02488 1.4e-220 spoIIP M stage II sporulation protein P
LMMEADAK_02489 5.9e-205 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LMMEADAK_02490 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
LMMEADAK_02491 1.7e-182 holA 2.7.7.7 L DNA polymerase III delta subunit
LMMEADAK_02492 0.0 comEC S Competence protein ComEC
LMMEADAK_02493 8e-105 comEB 3.5.4.12 F ComE operon protein 2
LMMEADAK_02494 5.6e-104 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
LMMEADAK_02495 2.2e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LMMEADAK_02496 4.2e-138 yqeM Q Methyltransferase
LMMEADAK_02497 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LMMEADAK_02498 3.3e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LMMEADAK_02499 1.7e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LMMEADAK_02500 4.8e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
LMMEADAK_02501 8.6e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LMMEADAK_02502 1.5e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LMMEADAK_02503 2e-94 yqeG S hydrolase of the HAD superfamily
LMMEADAK_02505 3.5e-140 yqeF E GDSL-like Lipase/Acylhydrolase
LMMEADAK_02506 4e-141 3.5.1.104 G Polysaccharide deacetylase
LMMEADAK_02507 4.7e-106 yqeD S SNARE associated Golgi protein
LMMEADAK_02508 1.9e-25 2.3.1.57 K Acetyltransferase (GNAT) domain
LMMEADAK_02509 9.7e-220 EGP Major facilitator Superfamily
LMMEADAK_02510 7.4e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LMMEADAK_02511 1.6e-266 cisA2 L Recombinase
LMMEADAK_02512 1.5e-97 EGP Major facilitator Superfamily
LMMEADAK_02513 1.7e-31 cadC3 K transcriptional
LMMEADAK_02514 4.6e-78 P Major Facilitator Superfamily
LMMEADAK_02515 1.3e-161 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LMMEADAK_02516 7.2e-76 yvbU K Transcriptional regulator
LMMEADAK_02517 5e-57 yqaB E IrrE N-terminal-like domain
LMMEADAK_02518 1.8e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LMMEADAK_02519 3.4e-160 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
LMMEADAK_02520 2.7e-91 K Transcriptional regulator PadR-like family
LMMEADAK_02521 9e-148 ydeE K AraC family transcriptional regulator
LMMEADAK_02522 3e-69 psiE S Belongs to the PsiE family
LMMEADAK_02523 1.3e-238 yrkQ T Histidine kinase
LMMEADAK_02524 1.3e-125 T Transcriptional regulator
LMMEADAK_02526 6.3e-216 yrkO P Protein of unknown function (DUF418)
LMMEADAK_02527 1.5e-103 yrkN K Acetyltransferase (GNAT) family
LMMEADAK_02528 1.1e-98 adk 2.7.4.3 F adenylate kinase activity
LMMEADAK_02529 3.5e-32 yyaR K acetyltransferase
LMMEADAK_02530 5.8e-64 tetL EGP Major facilitator Superfamily
LMMEADAK_02531 5.7e-81 yyaR K Acetyltransferase (GNAT) domain
LMMEADAK_02532 4.7e-93 yrdA S DinB family
LMMEADAK_02534 3.1e-147 S hydrolase
LMMEADAK_02535 2.9e-85 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
LMMEADAK_02536 2e-129 glvR K Helix-turn-helix domain, rpiR family
LMMEADAK_02537 9.6e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
LMMEADAK_02538 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
LMMEADAK_02539 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
LMMEADAK_02540 1.4e-183 romA S Beta-lactamase superfamily domain
LMMEADAK_02541 1.7e-31 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LMMEADAK_02542 2.8e-36 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LMMEADAK_02543 4.1e-164 yybE K Transcriptional regulator
LMMEADAK_02544 3.8e-213 ynfM EGP Major facilitator Superfamily
LMMEADAK_02545 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
LMMEADAK_02546 1.2e-100 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
LMMEADAK_02547 3.9e-93 yrhH Q methyltransferase
LMMEADAK_02549 8e-143 focA P Formate nitrite
LMMEADAK_02550 6e-61 yrhF S Uncharacterized conserved protein (DUF2294)
LMMEADAK_02551 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
LMMEADAK_02552 7e-81 yrhD S Protein of unknown function (DUF1641)
LMMEADAK_02553 1.3e-34 yrhC S YrhC-like protein
LMMEADAK_02554 9.8e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LMMEADAK_02555 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
LMMEADAK_02556 7.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LMMEADAK_02557 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
LMMEADAK_02558 4.1e-27 yrzA S Protein of unknown function (DUF2536)
LMMEADAK_02559 4.1e-66 yrrS S Protein of unknown function (DUF1510)
LMMEADAK_02560 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
LMMEADAK_02561 3.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LMMEADAK_02562 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
LMMEADAK_02563 6.1e-246 yegQ O COG0826 Collagenase and related proteases
LMMEADAK_02564 1.7e-173 yegQ O Peptidase U32
LMMEADAK_02565 9.5e-118 yrrM 2.1.1.104 S O-methyltransferase
LMMEADAK_02566 1.7e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LMMEADAK_02567 7.1e-46 yrzB S Belongs to the UPF0473 family
LMMEADAK_02568 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LMMEADAK_02569 8.5e-41 yrzL S Belongs to the UPF0297 family
LMMEADAK_02570 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LMMEADAK_02571 6.4e-164 yrrI S AI-2E family transporter
LMMEADAK_02572 5.4e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LMMEADAK_02573 3.2e-147 glnH ET Belongs to the bacterial solute-binding protein 3 family
LMMEADAK_02574 1.2e-109 gluC P ABC transporter
LMMEADAK_02575 2.2e-106 glnP P ABC transporter
LMMEADAK_02576 2.1e-08 S Protein of unknown function (DUF3918)
LMMEADAK_02577 2.9e-30 yrzR
LMMEADAK_02578 1.8e-83 yrrD S protein conserved in bacteria
LMMEADAK_02579 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LMMEADAK_02580 1.7e-18 S COG0457 FOG TPR repeat
LMMEADAK_02581 2.7e-221 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LMMEADAK_02582 1.8e-212 iscS 2.8.1.7 E Cysteine desulfurase
LMMEADAK_02583 7.8e-64 cymR K Transcriptional regulator
LMMEADAK_02584 5.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
LMMEADAK_02585 8.2e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
LMMEADAK_02586 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LMMEADAK_02587 2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
LMMEADAK_02590 5.3e-276 lytH 3.5.1.28 M COG3103 SH3 domain protein
LMMEADAK_02591 5.1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LMMEADAK_02592 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LMMEADAK_02593 7.7e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LMMEADAK_02594 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
LMMEADAK_02595 2.6e-47 yrvD S Lipopolysaccharide assembly protein A domain
LMMEADAK_02596 5.2e-84 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
LMMEADAK_02597 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LMMEADAK_02598 1.3e-50 yrzD S Post-transcriptional regulator
LMMEADAK_02599 7.2e-273 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LMMEADAK_02600 9.5e-110 yrbG S membrane
LMMEADAK_02601 2.4e-60 yrzE S Protein of unknown function (DUF3792)
LMMEADAK_02602 5.6e-37 yajC U Preprotein translocase subunit YajC
LMMEADAK_02603 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LMMEADAK_02604 1.1e-192 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LMMEADAK_02605 1.6e-20 yrzS S Protein of unknown function (DUF2905)
LMMEADAK_02606 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LMMEADAK_02607 1.3e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LMMEADAK_02608 3.7e-93 bofC S BofC C-terminal domain
LMMEADAK_02610 1.4e-46 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
LMMEADAK_02611 8.8e-146 safA M spore coat assembly protein SafA
LMMEADAK_02612 3.8e-212 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LMMEADAK_02613 1.2e-152 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
LMMEADAK_02614 3.1e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
LMMEADAK_02615 4.5e-224 nifS 2.8.1.7 E Cysteine desulfurase
LMMEADAK_02616 1.5e-92 niaR S small molecule binding protein (contains 3H domain)
LMMEADAK_02617 1.2e-160 pheA 4.2.1.51 E Prephenate dehydratase
LMMEADAK_02618 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
LMMEADAK_02619 3.8e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LMMEADAK_02620 4.3e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
LMMEADAK_02621 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LMMEADAK_02622 3.2e-56 ysxB J ribosomal protein
LMMEADAK_02623 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
LMMEADAK_02624 1.2e-160 spoIVFB S Stage IV sporulation protein
LMMEADAK_02625 1.7e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
LMMEADAK_02626 8e-143 minD D Belongs to the ParA family
LMMEADAK_02627 1.5e-97 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
LMMEADAK_02628 1.4e-84 mreD M shape-determining protein
LMMEADAK_02629 1.2e-157 mreC M Involved in formation and maintenance of cell shape
LMMEADAK_02630 4e-184 mreB D Rod shape-determining protein MreB
LMMEADAK_02631 1.8e-127 radC E Belongs to the UPF0758 family
LMMEADAK_02632 1.2e-100 maf D septum formation protein Maf
LMMEADAK_02633 1.9e-138 spoIIB S Sporulation related domain
LMMEADAK_02634 2.2e-91 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
LMMEADAK_02635 3e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LMMEADAK_02636 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LMMEADAK_02637 2.1e-25
LMMEADAK_02638 8.6e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LMMEADAK_02639 7e-222 spoVID M stage VI sporulation protein D
LMMEADAK_02640 2.3e-245 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
LMMEADAK_02641 2.3e-184 hemB 4.2.1.24 H Belongs to the ALAD family
LMMEADAK_02642 4.3e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
LMMEADAK_02643 2.1e-174 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
LMMEADAK_02644 3.6e-146 hemX O cytochrome C
LMMEADAK_02645 7e-248 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LMMEADAK_02646 1.3e-87 ysxD
LMMEADAK_02647 8.8e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
LMMEADAK_02648 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LMMEADAK_02649 1.1e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
LMMEADAK_02650 7.7e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LMMEADAK_02651 4.7e-214 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LMMEADAK_02652 2.4e-189 ysoA H Tetratricopeptide repeat
LMMEADAK_02653 6.2e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LMMEADAK_02654 8.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LMMEADAK_02655 4.8e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LMMEADAK_02656 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LMMEADAK_02657 5.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LMMEADAK_02658 1.6e-83 ilvN 2.2.1.6 E Acetolactate synthase
LMMEADAK_02659 0.0 ilvB 2.2.1.6 E Acetolactate synthase
LMMEADAK_02662 1.8e-12 pinR3 L Resolvase, N terminal domain
LMMEADAK_02663 3.3e-94 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
LMMEADAK_02664 1.1e-246 hsdM 2.1.1.72 L type I restriction-modification system
LMMEADAK_02665 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
LMMEADAK_02669 5.5e-89 ysnB S Phosphoesterase
LMMEADAK_02670 1.1e-101 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LMMEADAK_02671 6.9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LMMEADAK_02672 2.6e-197 gerM S COG5401 Spore germination protein
LMMEADAK_02673 2.7e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LMMEADAK_02674 7.4e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
LMMEADAK_02675 2e-30 gerE K Transcriptional regulator
LMMEADAK_02676 7.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
LMMEADAK_02677 1.3e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LMMEADAK_02678 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
LMMEADAK_02679 4.8e-108 sdhC C succinate dehydrogenase
LMMEADAK_02680 7.7e-79 yslB S Protein of unknown function (DUF2507)
LMMEADAK_02681 1.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
LMMEADAK_02682 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LMMEADAK_02683 2.5e-52 trxA O Belongs to the thioredoxin family
LMMEADAK_02684 3.5e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
LMMEADAK_02685 7.1e-178 etfA C Electron transfer flavoprotein
LMMEADAK_02686 2e-138 etfB C Electron transfer flavoprotein
LMMEADAK_02687 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
LMMEADAK_02688 9.2e-104 fadR K Transcriptional regulator
LMMEADAK_02689 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
LMMEADAK_02690 2.8e-125 ywbB S Protein of unknown function (DUF2711)
LMMEADAK_02691 4.7e-67 yshE S membrane
LMMEADAK_02692 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LMMEADAK_02693 0.0 polX L COG1796 DNA polymerase IV (family X)
LMMEADAK_02694 1.6e-83 cvpA S membrane protein, required for colicin V production
LMMEADAK_02695 9.1e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LMMEADAK_02696 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LMMEADAK_02697 2.2e-137 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_02698 1.2e-44 L COG2963 Transposase and inactivated derivatives
LMMEADAK_02699 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LMMEADAK_02700 1e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LMMEADAK_02701 1.4e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LMMEADAK_02702 2e-32 sspI S Belongs to the SspI family
LMMEADAK_02703 1.3e-204 ysfB KT regulator
LMMEADAK_02704 3.7e-260 glcD 1.1.3.15 C FAD binding domain
LMMEADAK_02705 3.4e-255 glcF C Glycolate oxidase
LMMEADAK_02706 0.0 cstA T Carbon starvation protein
LMMEADAK_02707 1.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
LMMEADAK_02708 4.4e-144 araQ G transport system permease
LMMEADAK_02709 2.9e-168 araP P PFAM binding-protein-dependent transport systems inner membrane component
LMMEADAK_02710 1.8e-253 araN G carbohydrate transport
LMMEADAK_02711 2.7e-224 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
LMMEADAK_02712 1.3e-140 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
LMMEADAK_02713 4.2e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
LMMEADAK_02714 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
LMMEADAK_02715 4e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
LMMEADAK_02716 1.8e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LMMEADAK_02717 8.1e-207 ysdC G COG1363 Cellulase M and related proteins
LMMEADAK_02718 9.2e-68 ysdB S Sigma-w pathway protein YsdB
LMMEADAK_02719 2e-42 ysdA S Membrane
LMMEADAK_02720 4.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LMMEADAK_02721 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LMMEADAK_02722 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LMMEADAK_02723 3.8e-109 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
LMMEADAK_02724 3.1e-40 lrgA S effector of murein hydrolase LrgA
LMMEADAK_02725 3.8e-131 lytT T COG3279 Response regulator of the LytR AlgR family
LMMEADAK_02726 0.0 lytS 2.7.13.3 T Histidine kinase
LMMEADAK_02727 7.1e-152 ysaA S HAD-hyrolase-like
LMMEADAK_02728 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LMMEADAK_02729 2.3e-153 ytxC S YtxC-like family
LMMEADAK_02730 2.7e-109 ytxB S SNARE associated Golgi protein
LMMEADAK_02731 4.3e-172 dnaI L Primosomal protein DnaI
LMMEADAK_02732 4.5e-258 dnaB L Membrane attachment protein
LMMEADAK_02733 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LMMEADAK_02734 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LMMEADAK_02735 3e-195 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LMMEADAK_02736 2e-67 ytcD K Transcriptional regulator
LMMEADAK_02737 4.5e-206 ytbD EGP Major facilitator Superfamily
LMMEADAK_02738 1.5e-160 ytbE S reductase
LMMEADAK_02739 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LMMEADAK_02740 9.5e-107 ytaF P Probably functions as a manganese efflux pump
LMMEADAK_02741 2.2e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LMMEADAK_02742 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LMMEADAK_02743 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
LMMEADAK_02744 7.7e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_02745 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
LMMEADAK_02746 1.2e-241 icd 1.1.1.42 C isocitrate
LMMEADAK_02747 6.2e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
LMMEADAK_02749 5.5e-53
LMMEADAK_02750 2.5e-47 yjdF S Protein of unknown function (DUF2992)
LMMEADAK_02751 4.3e-72 yeaL S membrane
LMMEADAK_02752 1.1e-193 ytvI S sporulation integral membrane protein YtvI
LMMEADAK_02753 1.6e-64 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
LMMEADAK_02754 2.2e-294 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LMMEADAK_02755 6.8e-181 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LMMEADAK_02756 1.2e-180 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LMMEADAK_02757 1e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LMMEADAK_02758 2.2e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
LMMEADAK_02759 0.0 dnaE 2.7.7.7 L DNA polymerase
LMMEADAK_02760 3.2e-56 ytrH S Sporulation protein YtrH
LMMEADAK_02761 2.5e-86 ytrI
LMMEADAK_02762 4.4e-23
LMMEADAK_02763 2.1e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
LMMEADAK_02764 2.4e-47 ytpI S YtpI-like protein
LMMEADAK_02765 7.5e-239 ytoI K transcriptional regulator containing CBS domains
LMMEADAK_02766 2.5e-129 ytkL S Belongs to the UPF0173 family
LMMEADAK_02767 1e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_02769 1.8e-264 argH 4.3.2.1 E argininosuccinate lyase
LMMEADAK_02770 1.5e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LMMEADAK_02771 1.2e-86 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
LMMEADAK_02772 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LMMEADAK_02773 1.1e-183 ytxK 2.1.1.72 L DNA methylase
LMMEADAK_02774 4.9e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LMMEADAK_02775 1.6e-60 ytfJ S Sporulation protein YtfJ
LMMEADAK_02776 5.5e-108 ytfI S Protein of unknown function (DUF2953)
LMMEADAK_02777 1.7e-87 yteJ S RDD family
LMMEADAK_02778 6.4e-182 sppA OU signal peptide peptidase SppA
LMMEADAK_02779 7.5e-152 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LMMEADAK_02780 0.0 ytcJ S amidohydrolase
LMMEADAK_02781 5.9e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LMMEADAK_02782 3.9e-31 sspB S spore protein
LMMEADAK_02783 7.3e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LMMEADAK_02784 1.1e-209 iscS2 2.8.1.7 E Cysteine desulfurase
LMMEADAK_02785 1.8e-240 braB E Component of the transport system for branched-chain amino acids
LMMEADAK_02786 1.2e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LMMEADAK_02787 7.8e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
LMMEADAK_02788 7.7e-109 yttP K Transcriptional regulator
LMMEADAK_02789 1.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
LMMEADAK_02790 1.3e-283 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
LMMEADAK_02791 5.7e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LMMEADAK_02792 4.2e-261 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LMMEADAK_02793 1.7e-99 yokH G SMI1 / KNR4 family
LMMEADAK_02794 7.5e-222 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LMMEADAK_02795 7.3e-09
LMMEADAK_02796 2e-91 yhbO 1.11.1.6, 3.5.1.124 S protease
LMMEADAK_02797 5.7e-141 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_02798 1.2e-44 L COG2963 Transposase and inactivated derivatives
LMMEADAK_02800 5.9e-140 E GDSL-like Lipase/Acylhydrolase family
LMMEADAK_02801 1.9e-150 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LMMEADAK_02802 4.4e-149 K Transcriptional regulator
LMMEADAK_02803 2.6e-124 azlC E AzlC protein
LMMEADAK_02804 8.7e-48 azlD S Branched-chain amino acid transport protein (AzlD)
LMMEADAK_02805 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LMMEADAK_02806 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
LMMEADAK_02807 8.9e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
LMMEADAK_02808 5.5e-118 acuB S Domain in cystathionine beta-synthase and other proteins.
LMMEADAK_02809 4.8e-229 acuC BQ histone deacetylase
LMMEADAK_02810 3.7e-120 motS N Flagellar motor protein
LMMEADAK_02811 5.1e-145 motA N flagellar motor
LMMEADAK_02812 6.4e-182 ccpA K catabolite control protein A
LMMEADAK_02813 1.9e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
LMMEADAK_02814 3.8e-43 ytxJ O Protein of unknown function (DUF2847)
LMMEADAK_02815 1.7e-16 ytxH S COG4980 Gas vesicle protein
LMMEADAK_02816 1.7e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
LMMEADAK_02817 4.6e-249 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LMMEADAK_02818 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
LMMEADAK_02819 1.1e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LMMEADAK_02820 3.7e-148 ytpQ S Belongs to the UPF0354 family
LMMEADAK_02821 1.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LMMEADAK_02822 2.7e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
LMMEADAK_02823 2.2e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LMMEADAK_02824 1.7e-51 ytzB S small secreted protein
LMMEADAK_02825 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
LMMEADAK_02826 7.1e-166 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
LMMEADAK_02827 8e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LMMEADAK_02828 3.5e-45 ytzH S YtzH-like protein
LMMEADAK_02829 6.3e-156 ytmP 2.7.1.89 M Phosphotransferase
LMMEADAK_02830 1.5e-177 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
LMMEADAK_02831 6.2e-171 ytlQ
LMMEADAK_02832 6.1e-102 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LMMEADAK_02833 1.3e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LMMEADAK_02834 1.2e-271 pepV 3.5.1.18 E Dipeptidase
LMMEADAK_02835 9.1e-229 pbuO S permease
LMMEADAK_02836 2.1e-216 ythQ U Bacterial ABC transporter protein EcsB
LMMEADAK_02837 1.1e-127 ythP V ABC transporter
LMMEADAK_02838 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
LMMEADAK_02839 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LMMEADAK_02840 6.6e-293 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LMMEADAK_02841 3.3e-236 ytfP S HI0933-like protein
LMMEADAK_02842 4.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
LMMEADAK_02843 9e-26 yteV S Sporulation protein Cse60
LMMEADAK_02844 1.3e-185 msmR K Transcriptional regulator
LMMEADAK_02845 2.7e-246 msmE G Bacterial extracellular solute-binding protein
LMMEADAK_02846 3.1e-167 amyD G Binding-protein-dependent transport system inner membrane component
LMMEADAK_02847 9e-142 amyC P ABC transporter (permease)
LMMEADAK_02848 5.8e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
LMMEADAK_02849 5.4e-86 M Acetyltransferase (GNAT) domain
LMMEADAK_02850 2.1e-51 ytwF P Sulfurtransferase
LMMEADAK_02851 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LMMEADAK_02852 1.2e-52 ytvB S Protein of unknown function (DUF4257)
LMMEADAK_02853 6.2e-140 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
LMMEADAK_02854 4.7e-208 yttB EGP Major facilitator Superfamily
LMMEADAK_02855 6.5e-128 ywaF S Integral membrane protein
LMMEADAK_02856 0.0 bceB V ABC transporter (permease)
LMMEADAK_02857 9.8e-135 bceA V ABC transporter, ATP-binding protein
LMMEADAK_02858 1.4e-170 T PhoQ Sensor
LMMEADAK_02859 8.2e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_02860 1e-219 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
LMMEADAK_02861 1.3e-125 ytrE V ABC transporter, ATP-binding protein
LMMEADAK_02862 2.4e-149
LMMEADAK_02863 7.7e-172 P ABC-2 family transporter protein
LMMEADAK_02864 3.8e-171 S ABC-2 family transporter protein
LMMEADAK_02865 3.8e-162 ytrB P abc transporter atp-binding protein
LMMEADAK_02866 3.9e-66 ytrA K GntR family transcriptional regulator
LMMEADAK_02867 1.3e-39 ytzC S Protein of unknown function (DUF2524)
LMMEADAK_02868 2.1e-190 yhcC S Fe-S oxidoreductase
LMMEADAK_02869 8.7e-107 ytqB J Putative rRNA methylase
LMMEADAK_02871 3.6e-143 glpQ 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
LMMEADAK_02872 2.4e-211 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
LMMEADAK_02873 2.9e-150 ytpA 3.1.1.5 I Alpha beta hydrolase
LMMEADAK_02874 2.3e-58 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LMMEADAK_02875 1.9e-261 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
LMMEADAK_02876 0.0 asnB 6.3.5.4 E Asparagine synthase
LMMEADAK_02877 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LMMEADAK_02878 1.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LMMEADAK_02879 1.6e-38 ytmB S Protein of unknown function (DUF2584)
LMMEADAK_02880 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
LMMEADAK_02881 7.3e-186 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
LMMEADAK_02882 3.2e-144 ytlC P ABC transporter
LMMEADAK_02883 8.1e-127 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
LMMEADAK_02884 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
LMMEADAK_02885 1.7e-61 ytkC S Bacteriophage holin family
LMMEADAK_02886 1.6e-76 dps P Belongs to the Dps family
LMMEADAK_02888 2.7e-76 ytkA S YtkA-like
LMMEADAK_02889 5.7e-88 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LMMEADAK_02890 4e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LMMEADAK_02891 3.6e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LMMEADAK_02892 3e-40 rpmE2 J Ribosomal protein L31
LMMEADAK_02893 2.6e-239 cydA 1.10.3.14 C oxidase, subunit
LMMEADAK_02894 2.6e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
LMMEADAK_02895 2.3e-24 S Domain of Unknown Function (DUF1540)
LMMEADAK_02896 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
LMMEADAK_02897 1.7e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
LMMEADAK_02898 2.4e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LMMEADAK_02899 1.7e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
LMMEADAK_02900 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LMMEADAK_02901 1.6e-271 menF 5.4.4.2 HQ Isochorismate synthase
LMMEADAK_02902 2e-132 dksA T COG1734 DnaK suppressor protein
LMMEADAK_02903 1.5e-77 tspO T membrane
LMMEADAK_02912 7.8e-08
LMMEADAK_02913 1.3e-09
LMMEADAK_02920 1.6e-08
LMMEADAK_02925 3.4e-39 S COG NOG14552 non supervised orthologous group
LMMEADAK_02926 1.4e-96 thiT S Thiamine transporter protein (Thia_YuaJ)
LMMEADAK_02927 2.5e-177 yuaG 3.4.21.72 S protein conserved in bacteria
LMMEADAK_02928 6.6e-85 yuaF OU Membrane protein implicated in regulation of membrane protease activity
LMMEADAK_02929 4.3e-83 yuaE S DinB superfamily
LMMEADAK_02930 2.5e-109 yuaD S MOSC domain
LMMEADAK_02931 1.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
LMMEADAK_02932 1.2e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
LMMEADAK_02933 2.7e-97 yuaC K Belongs to the GbsR family
LMMEADAK_02934 2.1e-94 yuaB
LMMEADAK_02935 1.6e-120 ktrA P COG0569 K transport systems, NAD-binding component
LMMEADAK_02936 4.8e-146 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LMMEADAK_02937 1.3e-218 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LMMEADAK_02938 9.6e-123 G Cupin
LMMEADAK_02939 1.9e-50 yjcN
LMMEADAK_02943 5.8e-131 S Aspartate phosphatase response regulator
LMMEADAK_02947 1.2e-70 S peptidoglycan catabolic process
LMMEADAK_02949 2.3e-145 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LMMEADAK_02950 9e-196 yubA S transporter activity
LMMEADAK_02951 1.4e-184 ygjR S Oxidoreductase
LMMEADAK_02952 5.1e-98 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
LMMEADAK_02953 2.8e-237 mcpA NT chemotaxis protein
LMMEADAK_02954 1.9e-225 mcpA NT chemotaxis protein
LMMEADAK_02955 1.6e-240 mcpA NT chemotaxis protein
LMMEADAK_02956 4.5e-219 mcpA NT chemotaxis protein
LMMEADAK_02957 6.4e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
LMMEADAK_02958 4.8e-41
LMMEADAK_02959 6.6e-190 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
LMMEADAK_02960 1.3e-75 yugU S Uncharacterised protein family UPF0047
LMMEADAK_02961 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
LMMEADAK_02962 3.9e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
LMMEADAK_02963 8.3e-117 yugP S Zn-dependent protease
LMMEADAK_02964 4.5e-18
LMMEADAK_02965 1.1e-26 mstX S Membrane-integrating protein Mistic
LMMEADAK_02966 1.8e-181 yugO P COG1226 Kef-type K transport systems
LMMEADAK_02967 2.8e-72 yugN S YugN-like family
LMMEADAK_02969 8.7e-259 pgi 5.3.1.9 G Belongs to the GPI family
LMMEADAK_02971 8.8e-96 S NADPH-dependent FMN reductase
LMMEADAK_02972 1.4e-118 ycaC Q Isochorismatase family
LMMEADAK_02973 3.7e-229 yugK C Dehydrogenase
LMMEADAK_02974 4.9e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
LMMEADAK_02975 1.8e-34 yuzA S Domain of unknown function (DUF378)
LMMEADAK_02976 6e-59 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
LMMEADAK_02977 5.5e-209 yugH 2.6.1.1 E Aminotransferase
LMMEADAK_02978 9.9e-83 alaR K Transcriptional regulator
LMMEADAK_02979 5.5e-155 yugF I Hydrolase
LMMEADAK_02980 1.4e-40 yugE S Domain of unknown function (DUF1871)
LMMEADAK_02981 2.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LMMEADAK_02982 2.6e-228 T PhoQ Sensor
LMMEADAK_02983 3.1e-68 kapB G Kinase associated protein B
LMMEADAK_02984 1.7e-117 kapD L the KinA pathway to sporulation
LMMEADAK_02985 1.5e-185 yuxJ EGP Major facilitator Superfamily
LMMEADAK_02986 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
LMMEADAK_02987 2.2e-72 yuxK S protein conserved in bacteria
LMMEADAK_02988 9.3e-74 yufK S Family of unknown function (DUF5366)
LMMEADAK_02989 1.5e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
LMMEADAK_02990 2.7e-126 dcuR T COG4565 Response regulator of citrate malate metabolism
LMMEADAK_02991 2.4e-195 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LMMEADAK_02992 2.1e-285 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LMMEADAK_02993 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
LMMEADAK_02994 1.6e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
LMMEADAK_02995 1.8e-12
LMMEADAK_02996 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
LMMEADAK_02997 1.8e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LMMEADAK_02998 8.9e-51 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LMMEADAK_02999 1.9e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LMMEADAK_03000 5.3e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LMMEADAK_03001 1.1e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
LMMEADAK_03002 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
LMMEADAK_03003 3.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
LMMEADAK_03004 1.8e-113 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LMMEADAK_03005 0.0 comP 2.7.13.3 T Histidine kinase
LMMEADAK_03007 2.1e-94 comQ H Polyprenyl synthetase
LMMEADAK_03009 1.1e-51 yuzC
LMMEADAK_03010 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
LMMEADAK_03011 2.1e-282 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LMMEADAK_03012 1.1e-103 pncA Q COG1335 Amidases related to nicotinamidase
LMMEADAK_03013 7.2e-68 yueI S Protein of unknown function (DUF1694)
LMMEADAK_03014 8.2e-38 yueH S YueH-like protein
LMMEADAK_03015 6.4e-34 yueG S Spore germination protein gerPA/gerPF
LMMEADAK_03016 2.5e-187 yueF S transporter activity
LMMEADAK_03017 1.6e-22 S Protein of unknown function (DUF2642)
LMMEADAK_03018 3.7e-96 yueE S phosphohydrolase
LMMEADAK_03019 9.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_03020 6.9e-78 yueC S Family of unknown function (DUF5383)
LMMEADAK_03021 0.0 esaA S type VII secretion protein EsaA
LMMEADAK_03022 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
LMMEADAK_03023 2.8e-206 essB S WXG100 protein secretion system (Wss), protein YukC
LMMEADAK_03024 3.9e-40 yukD S WXG100 protein secretion system (Wss), protein YukD
LMMEADAK_03025 3.3e-46 esxA S Belongs to the WXG100 family
LMMEADAK_03026 1.5e-228 yukF QT Transcriptional regulator
LMMEADAK_03027 1e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
LMMEADAK_03028 8.3e-133 yukJ S Uncharacterized conserved protein (DUF2278)
LMMEADAK_03029 1.3e-34 mbtH S MbtH-like protein
LMMEADAK_03030 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_03031 2.9e-173 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
LMMEADAK_03032 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
LMMEADAK_03033 1.2e-224 entC 5.4.4.2 HQ Isochorismate synthase
LMMEADAK_03034 6.6e-134 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LMMEADAK_03035 1.6e-165 besA S Putative esterase
LMMEADAK_03036 1.2e-119 yuiH S Oxidoreductase molybdopterin binding domain
LMMEADAK_03037 1.5e-101 bioY S Biotin biosynthesis protein
LMMEADAK_03038 3.7e-209 yuiF S antiporter
LMMEADAK_03039 4e-281 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LMMEADAK_03040 5.9e-77 yuiD S protein conserved in bacteria
LMMEADAK_03041 3.5e-117 yuiC S protein conserved in bacteria
LMMEADAK_03042 9.9e-28 yuiB S Putative membrane protein
LMMEADAK_03043 1.2e-235 yumB 1.6.99.3 C NADH dehydrogenase
LMMEADAK_03044 5e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
LMMEADAK_03046 1.6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
LMMEADAK_03047 4.8e-29
LMMEADAK_03048 6.3e-72 CP Membrane
LMMEADAK_03049 3.3e-124 V ABC transporter
LMMEADAK_03051 3.2e-32 S Bacteriocin class IId cyclical uberolysin-like
LMMEADAK_03054 2.8e-91 rimJ 2.3.1.128 J Alanine acetyltransferase
LMMEADAK_03055 1.1e-138 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
LMMEADAK_03056 5.3e-62 erpA S Belongs to the HesB IscA family
LMMEADAK_03057 1.6e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LMMEADAK_03058 1.7e-213 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LMMEADAK_03059 2.4e-39 yuzB S Belongs to the UPF0349 family
LMMEADAK_03060 5.5e-208 yutJ 1.6.99.3 C NADH dehydrogenase
LMMEADAK_03061 6.7e-56 yuzD S protein conserved in bacteria
LMMEADAK_03062 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
LMMEADAK_03063 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
LMMEADAK_03064 2.2e-168 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LMMEADAK_03065 1.5e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LMMEADAK_03066 7.1e-242 hom 1.1.1.3 E homoserine dehydrogenase
LMMEADAK_03067 7.1e-197 yutH S Spore coat protein
LMMEADAK_03068 8.7e-85 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
LMMEADAK_03069 7.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LMMEADAK_03070 4.3e-74 yutE S Protein of unknown function DUF86
LMMEADAK_03071 1.7e-47 yutD S protein conserved in bacteria
LMMEADAK_03072 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LMMEADAK_03073 7.9e-193 lytH M Peptidase, M23
LMMEADAK_03074 2.5e-130 yunB S Sporulation protein YunB (Spo_YunB)
LMMEADAK_03075 5.3e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LMMEADAK_03076 1.8e-145 yunE S membrane transporter protein
LMMEADAK_03077 1.4e-169 yunF S Protein of unknown function DUF72
LMMEADAK_03078 5.2e-62 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
LMMEADAK_03079 5e-262 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
LMMEADAK_03080 8e-304 pucR QT COG2508 Regulator of polyketide synthase expression
LMMEADAK_03081 1.5e-11 yqbD 2.1.1.72 L Putative phage serine protease XkdF
LMMEADAK_03083 1.9e-212 blt EGP Major facilitator Superfamily
LMMEADAK_03084 4.6e-238 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
LMMEADAK_03085 1.1e-236 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
LMMEADAK_03086 7.8e-168 bsn L Ribonuclease
LMMEADAK_03087 3.7e-207 msmX P Belongs to the ABC transporter superfamily
LMMEADAK_03088 1.2e-134 yurK K UTRA
LMMEADAK_03089 1.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
LMMEADAK_03090 1.4e-164 yurM P COG0395 ABC-type sugar transport system, permease component
LMMEADAK_03091 1.2e-158 yurN G Binding-protein-dependent transport system inner membrane component
LMMEADAK_03092 4e-245 yurO G COG1653 ABC-type sugar transport system, periplasmic component
LMMEADAK_03093 3e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
LMMEADAK_03094 4.5e-166 K helix_turn_helix, mercury resistance
LMMEADAK_03095 4e-14
LMMEADAK_03096 4.5e-76
LMMEADAK_03097 2.1e-22 S Sporulation delaying protein SdpA
LMMEADAK_03099 3.1e-65 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
LMMEADAK_03100 7.3e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
LMMEADAK_03101 1.9e-124 Q ubiE/COQ5 methyltransferase family
LMMEADAK_03102 7.2e-80 yncE S Protein of unknown function (DUF2691)
LMMEADAK_03103 2.6e-149 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
LMMEADAK_03104 3e-270 sufB O FeS cluster assembly
LMMEADAK_03105 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
LMMEADAK_03106 7.9e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LMMEADAK_03107 2e-244 sufD O assembly protein SufD
LMMEADAK_03108 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LMMEADAK_03109 7.6e-64 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LMMEADAK_03110 2.3e-145 metQ P Belongs to the NlpA lipoprotein family
LMMEADAK_03111 1.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
LMMEADAK_03112 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LMMEADAK_03113 5e-57 yusD S SCP-2 sterol transfer family
LMMEADAK_03114 1.6e-54 yusE CO Thioredoxin
LMMEADAK_03115 6.4e-57 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
LMMEADAK_03116 3.7e-40 yusG S Protein of unknown function (DUF2553)
LMMEADAK_03117 2.4e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
LMMEADAK_03118 6.2e-63 arsC 1.20.4.1 P Belongs to the ArsC family
LMMEADAK_03119 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
LMMEADAK_03120 1.6e-216 fadA 2.3.1.16 I Belongs to the thiolase family
LMMEADAK_03121 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
LMMEADAK_03122 8.1e-168 fadM E Proline dehydrogenase
LMMEADAK_03123 1.8e-210 yusP P Major facilitator superfamily
LMMEADAK_03124 8.8e-43
LMMEADAK_03125 1.1e-53 yusN M Coat F domain
LMMEADAK_03126 5.7e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
LMMEADAK_03127 8.1e-288 yusP P Major facilitator superfamily
LMMEADAK_03128 3.3e-158 ywbI2 K Transcriptional regulator
LMMEADAK_03129 4.1e-141 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
LMMEADAK_03130 3.9e-190 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LMMEADAK_03131 3.3e-39 yusU S Protein of unknown function (DUF2573)
LMMEADAK_03132 1.4e-150 yusV 3.6.3.34 HP ABC transporter
LMMEADAK_03133 7.2e-45 S YusW-like protein
LMMEADAK_03134 0.0 pepF2 E COG1164 Oligoendopeptidase F
LMMEADAK_03135 9.6e-155 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LMMEADAK_03136 1.6e-79 dps P Belongs to the Dps family
LMMEADAK_03137 8.3e-241 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LMMEADAK_03138 9.8e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_03139 7.9e-252 cssS 2.7.13.3 T PhoQ Sensor
LMMEADAK_03140 3.4e-24
LMMEADAK_03141 1e-157 yuxN K Transcriptional regulator
LMMEADAK_03142 3.9e-262 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
LMMEADAK_03143 6.6e-24 S Protein of unknown function (DUF3970)
LMMEADAK_03144 2.2e-260 gerAA EG Spore germination protein
LMMEADAK_03145 6.6e-188 gerAB E Spore germination protein
LMMEADAK_03146 1.2e-208 gerAC S Spore germination B3/ GerAC like, C-terminal
LMMEADAK_03147 7.3e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LMMEADAK_03148 2.3e-193 vraS 2.7.13.3 T Histidine kinase
LMMEADAK_03149 4.7e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
LMMEADAK_03150 2e-115 liaG S Putative adhesin
LMMEADAK_03151 1.5e-94 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
LMMEADAK_03152 8.1e-45 liaI S membrane
LMMEADAK_03153 8.8e-229 yvqJ EGP Major facilitator Superfamily
LMMEADAK_03154 3.7e-102 yvqK 2.5.1.17 S Adenosyltransferase
LMMEADAK_03155 4.8e-224 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
LMMEADAK_03156 3.3e-181 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_03157 1.9e-167 yvrC P ABC transporter substrate-binding protein
LMMEADAK_03158 3.1e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LMMEADAK_03159 3.8e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
LMMEADAK_03160 0.0 T PhoQ Sensor
LMMEADAK_03161 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_03162 1.1e-36
LMMEADAK_03163 9.9e-103 yvrI K RNA polymerase
LMMEADAK_03164 1.6e-15 S YvrJ protein family
LMMEADAK_03165 3.5e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
LMMEADAK_03166 3.2e-66 yvrL S Regulatory protein YrvL
LMMEADAK_03167 1e-137 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_03168 1.2e-44 L COG2963 Transposase and inactivated derivatives
LMMEADAK_03169 1.4e-147 fhuC 3.6.3.34 HP ABC transporter
LMMEADAK_03170 4e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_03171 2.8e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_03172 6.8e-178 fhuD P ABC transporter
LMMEADAK_03173 3.5e-126 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LMMEADAK_03174 1.8e-235 yvsH E Arginine ornithine antiporter
LMMEADAK_03175 3.6e-14 S Small spore protein J (Spore_SspJ)
LMMEADAK_03176 1.3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
LMMEADAK_03177 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LMMEADAK_03178 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
LMMEADAK_03179 1.4e-139 modA P COG0725 ABC-type molybdate transport system, periplasmic component
LMMEADAK_03180 2.3e-94 modB P COG4149 ABC-type molybdate transport system, permease component
LMMEADAK_03181 2e-112 yfiK K Regulator
LMMEADAK_03182 1.5e-179 T Histidine kinase
LMMEADAK_03183 1.2e-171 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
LMMEADAK_03184 8.8e-193 yfiM V ABC-2 type transporter
LMMEADAK_03185 3.9e-199 yfiN V COG0842 ABC-type multidrug transport system, permease component
LMMEADAK_03186 1.5e-155 yvgN S reductase
LMMEADAK_03187 4.9e-87 yvgO
LMMEADAK_03188 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
LMMEADAK_03189 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
LMMEADAK_03190 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LMMEADAK_03191 0.0 helD 3.6.4.12 L DNA helicase
LMMEADAK_03192 3.1e-99 yvgT S membrane
LMMEADAK_03193 2.6e-141 S Metallo-peptidase family M12
LMMEADAK_03194 6.6e-72 bdbC O Required for disulfide bond formation in some proteins
LMMEADAK_03195 3.4e-102 bdbD O Thioredoxin
LMMEADAK_03196 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
LMMEADAK_03197 0.0 copA 3.6.3.54 P P-type ATPase
LMMEADAK_03198 2.6e-29 copZ P Heavy-metal-associated domain
LMMEADAK_03199 3.7e-48 csoR S transcriptional
LMMEADAK_03200 1.2e-194 yvaA 1.1.1.371 S Oxidoreductase
LMMEADAK_03201 1.1e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LMMEADAK_03202 2.1e-162 K Helix-turn-helix XRE-family like proteins
LMMEADAK_03203 6.1e-219 ynfM EGP Major Facilitator Superfamily
LMMEADAK_03204 1.2e-70 4.1.1.44 S Carboxymuconolactone decarboxylase family
LMMEADAK_03205 4.4e-146 S Amidohydrolase
LMMEADAK_03206 2.7e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LMMEADAK_03207 1.5e-46 ytnI O COG0695 Glutaredoxin and related proteins
LMMEADAK_03208 1.1e-181 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LMMEADAK_03209 9.5e-141 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
LMMEADAK_03210 1.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
LMMEADAK_03211 1.6e-121 tcyL P Binding-protein-dependent transport system inner membrane component
LMMEADAK_03212 4.9e-148 tcyK M Bacterial periplasmic substrate-binding proteins
LMMEADAK_03213 1.3e-129 ytmJ ET Bacterial periplasmic substrate-binding proteins
LMMEADAK_03214 3e-101 ytmI K Acetyltransferase (GNAT) domain
LMMEADAK_03215 1.5e-161 ytlI K LysR substrate binding domain
LMMEADAK_03216 1.5e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LMMEADAK_03217 1.4e-47 yrdF K ribonuclease inhibitor
LMMEADAK_03219 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LMMEADAK_03220 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LMMEADAK_03221 7.4e-143 est 3.1.1.1 S Carboxylesterase
LMMEADAK_03222 4.8e-24 secG U Preprotein translocase subunit SecG
LMMEADAK_03223 6e-35 yvzC K Transcriptional
LMMEADAK_03224 1e-69 K transcriptional
LMMEADAK_03225 1e-72 yvaO K Cro/C1-type HTH DNA-binding domain
LMMEADAK_03226 8.8e-53 yodB K transcriptional
LMMEADAK_03227 5.9e-258 T His Kinase A (phosphoacceptor) domain
LMMEADAK_03228 2e-123 K Transcriptional regulatory protein, C terminal
LMMEADAK_03229 3.3e-138 mutG S ABC-2 family transporter protein
LMMEADAK_03230 1.4e-122 spaE S ABC-2 family transporter protein
LMMEADAK_03231 7.1e-127 mutF V ABC transporter, ATP-binding protein
LMMEADAK_03232 2.3e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LMMEADAK_03233 2.2e-173 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LMMEADAK_03234 2.7e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LMMEADAK_03235 6.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LMMEADAK_03236 4.3e-76 yvbF K Belongs to the GbsR family
LMMEADAK_03237 3.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
LMMEADAK_03238 1.2e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
LMMEADAK_03239 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
LMMEADAK_03240 6.7e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
LMMEADAK_03241 1.9e-98 yvbF K Belongs to the GbsR family
LMMEADAK_03242 1.5e-104 yvbG U UPF0056 membrane protein
LMMEADAK_03243 1.4e-119 exoY M Membrane
LMMEADAK_03244 0.0 tcaA S response to antibiotic
LMMEADAK_03245 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
LMMEADAK_03246 8.6e-213 EGP Major facilitator Superfamily
LMMEADAK_03247 1e-178
LMMEADAK_03248 9.8e-126 S GlcNAc-PI de-N-acetylase
LMMEADAK_03249 2.5e-143 C WbqC-like protein family
LMMEADAK_03250 1.7e-149 M Protein involved in cellulose biosynthesis
LMMEADAK_03251 1.8e-234 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LMMEADAK_03252 1.2e-171 5.1.3.2 M GDP-mannose 4,6 dehydratase
LMMEADAK_03253 6.2e-218 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LMMEADAK_03254 2.3e-256 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LMMEADAK_03255 6.2e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
LMMEADAK_03256 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LMMEADAK_03257 7.5e-299 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
LMMEADAK_03258 6.6e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LMMEADAK_03259 1.7e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LMMEADAK_03260 3.1e-184 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LMMEADAK_03261 2.3e-187 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LMMEADAK_03263 7.4e-253 araE EGP Major facilitator Superfamily
LMMEADAK_03264 6.5e-204 araR K transcriptional
LMMEADAK_03265 9.7e-42
LMMEADAK_03266 1.6e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LMMEADAK_03267 2.2e-125 yvbU K Transcriptional regulator
LMMEADAK_03268 3.5e-158 yvbV EG EamA-like transporter family
LMMEADAK_03269 2.2e-214 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
LMMEADAK_03270 1.5e-260
LMMEADAK_03271 8.7e-184 purR7 5.1.1.1 K Transcriptional regulator
LMMEADAK_03272 1.2e-115 yyaS S Membrane
LMMEADAK_03273 6.7e-167 3.1.3.104 S hydrolases of the HAD superfamily
LMMEADAK_03274 3.5e-152 ybbH_1 K RpiR family transcriptional regulator
LMMEADAK_03275 3.2e-297 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
LMMEADAK_03276 2.8e-225 gntP EG COG2610 H gluconate symporter and related permeases
LMMEADAK_03278 2.8e-31 M nucleic acid phosphodiester bond hydrolysis
LMMEADAK_03279 3.6e-134 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LMMEADAK_03280 6.2e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
LMMEADAK_03281 3.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
LMMEADAK_03282 1.8e-223 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LMMEADAK_03283 1.3e-120 yvfI K COG2186 Transcriptional regulators
LMMEADAK_03284 5.5e-303 yvfH C L-lactate permease
LMMEADAK_03285 2.6e-244 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
LMMEADAK_03286 2.7e-32 yvfG S YvfG protein
LMMEADAK_03287 1.4e-189 yvfF GM Exopolysaccharide biosynthesis protein
LMMEADAK_03288 4.8e-221 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
LMMEADAK_03289 2.3e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
LMMEADAK_03290 4.4e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LMMEADAK_03291 1.4e-273 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LMMEADAK_03292 4.4e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
LMMEADAK_03293 4.4e-205 epsI GM pyruvyl transferase
LMMEADAK_03294 2.9e-193 epsH GT2 S Glycosyltransferase like family 2
LMMEADAK_03295 1e-204 epsG S EpsG family
LMMEADAK_03296 2.1e-213 epsF GT4 M Glycosyl transferases group 1
LMMEADAK_03297 1.8e-161 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
LMMEADAK_03298 5.7e-219 epsD GT4 M Glycosyl transferase 4-like
LMMEADAK_03299 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
LMMEADAK_03300 1.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
LMMEADAK_03301 3.8e-120 ywqC M biosynthesis protein
LMMEADAK_03302 3.3e-77 slr K transcriptional
LMMEADAK_03303 6.4e-284 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
LMMEADAK_03305 8.3e-96 ywjB H RibD C-terminal domain
LMMEADAK_03306 3.7e-111 yyaS S Membrane
LMMEADAK_03307 8.4e-93 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LMMEADAK_03308 5.5e-94 padC Q Phenolic acid decarboxylase
LMMEADAK_03309 5.9e-16 S Protein of unknown function (DUF1433)
LMMEADAK_03310 8.5e-38 S Protein of unknown function (DUF1433)
LMMEADAK_03311 1.8e-16 S Protein of unknown function (DUF1433)
LMMEADAK_03312 4.6e-258 I Pfam Lipase (class 3)
LMMEADAK_03313 3.5e-46
LMMEADAK_03314 2.1e-93 yybG S Pentapeptide repeats (8 copies)
LMMEADAK_03315 2e-61 L Phage integrase family
LMMEADAK_03317 4.4e-296 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
LMMEADAK_03318 1.1e-218 rafB P LacY proton/sugar symporter
LMMEADAK_03319 1.7e-184 scrR K transcriptional
LMMEADAK_03320 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LMMEADAK_03321 1.3e-162 yraN K Transcriptional regulator
LMMEADAK_03322 3.9e-212 yraM S PrpF protein
LMMEADAK_03323 6.8e-251 EGP Sugar (and other) transporter
LMMEADAK_03324 2.7e-11 yvdD 3.2.2.10 S Belongs to the LOG family
LMMEADAK_03325 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
LMMEADAK_03326 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
LMMEADAK_03327 1.9e-281 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
LMMEADAK_03328 3.7e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
LMMEADAK_03329 3.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LMMEADAK_03330 1.7e-79 M Ribonuclease
LMMEADAK_03331 1.3e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
LMMEADAK_03332 4.7e-36 crh G Phosphocarrier protein Chr
LMMEADAK_03333 3.1e-170 whiA K May be required for sporulation
LMMEADAK_03334 1.7e-176 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LMMEADAK_03335 1.1e-166 rapZ S Displays ATPase and GTPase activities
LMMEADAK_03336 4.2e-86 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LMMEADAK_03337 3.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LMMEADAK_03338 2.1e-122 usp CBM50 M protein conserved in bacteria
LMMEADAK_03339 2.9e-276 S COG0457 FOG TPR repeat
LMMEADAK_03340 3.2e-192 sasA T Histidine kinase
LMMEADAK_03341 1.9e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_03342 1e-57
LMMEADAK_03343 0.0 msbA2 3.6.3.44 V ABC transporter
LMMEADAK_03344 8.1e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
LMMEADAK_03345 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LMMEADAK_03346 1.9e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LMMEADAK_03347 3.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LMMEADAK_03348 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LMMEADAK_03349 4.7e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LMMEADAK_03350 2.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LMMEADAK_03351 3.6e-208 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LMMEADAK_03352 9.1e-138 yvpB NU protein conserved in bacteria
LMMEADAK_03353 2.4e-76 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
LMMEADAK_03354 8.3e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
LMMEADAK_03355 3.4e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LMMEADAK_03356 1.3e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LMMEADAK_03357 3.6e-224 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LMMEADAK_03358 1.2e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LMMEADAK_03359 1.1e-133 yvoA K transcriptional
LMMEADAK_03360 1.6e-105 yxaF K Transcriptional regulator
LMMEADAK_03361 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
LMMEADAK_03362 3.9e-41 yvlD S Membrane
LMMEADAK_03363 9.6e-26 pspB KT PspC domain
LMMEADAK_03364 9.2e-166 yvlB S Putative adhesin
LMMEADAK_03365 8e-49 yvlA
LMMEADAK_03366 2.2e-32 yvkN
LMMEADAK_03367 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
LMMEADAK_03368 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LMMEADAK_03369 7.6e-33 csbA S protein conserved in bacteria
LMMEADAK_03370 0.0 yvkC 2.7.9.2 GT Phosphotransferase
LMMEADAK_03371 2.6e-109 yvkB K Transcriptional regulator
LMMEADAK_03372 1.1e-226 yvkA EGP Major facilitator Superfamily
LMMEADAK_03373 5e-49 bacT Q Thioesterase domain
LMMEADAK_03374 6.6e-177 S Psort location CytoplasmicMembrane, score
LMMEADAK_03375 1.4e-49 E Saccharopine dehydrogenase
LMMEADAK_03376 5.3e-99 V ABC transporter transmembrane region
LMMEADAK_03377 0.0 Q TIGRFAM amino acid adenylation domain
LMMEADAK_03378 0.0 Q TIGRFAM amino acid adenylation domain
LMMEADAK_03379 4.7e-47 IQ Enoyl-(Acyl carrier protein) reductase
LMMEADAK_03381 2.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LMMEADAK_03382 1.5e-55 swrA S Swarming motility protein
LMMEADAK_03383 2.7e-255 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
LMMEADAK_03384 7e-227 ywoF P Right handed beta helix region
LMMEADAK_03385 9.2e-156 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LMMEADAK_03386 1e-122 ftsE D cell division ATP-binding protein FtsE
LMMEADAK_03387 2.8e-36 cccB C COG2010 Cytochrome c, mono- and diheme variants
LMMEADAK_03388 9.3e-150 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
LMMEADAK_03389 1.4e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LMMEADAK_03390 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LMMEADAK_03391 3.7e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LMMEADAK_03392 2.2e-66
LMMEADAK_03393 2.6e-10 fliT S bacterial-type flagellum organization
LMMEADAK_03394 3e-66 fliS N flagellar protein FliS
LMMEADAK_03395 3.1e-244 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LMMEADAK_03396 2.1e-100 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LMMEADAK_03397 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LMMEADAK_03398 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
LMMEADAK_03399 1.2e-79 yviE
LMMEADAK_03400 6.1e-163 flgL N Belongs to the bacterial flagellin family
LMMEADAK_03401 6.3e-274 flgK N flagellar hook-associated protein
LMMEADAK_03402 8.9e-81 flgN NOU FlgN protein
LMMEADAK_03403 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
LMMEADAK_03404 2.4e-74 yvyF S flagellar protein
LMMEADAK_03405 2.2e-76 comFC S Phosphoribosyl transferase domain
LMMEADAK_03406 1.7e-42 comFB S Late competence development protein ComFB
LMMEADAK_03407 1.1e-259 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LMMEADAK_03408 5.5e-158 degV S protein conserved in bacteria
LMMEADAK_03409 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LMMEADAK_03410 1.7e-181 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
LMMEADAK_03411 3.8e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
LMMEADAK_03412 2e-166 yvhJ K Transcriptional regulator
LMMEADAK_03413 1.1e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
LMMEADAK_03414 1.4e-239 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
LMMEADAK_03415 6.8e-144 tuaG GT2 M Glycosyltransferase like family 2
LMMEADAK_03416 1.6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
LMMEADAK_03417 1.7e-257 tuaE M Teichuronic acid biosynthesis protein
LMMEADAK_03418 3.9e-251 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LMMEADAK_03419 4.9e-221 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
LMMEADAK_03420 3.3e-256 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
LMMEADAK_03421 6.2e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
LMMEADAK_03422 5.1e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
LMMEADAK_03423 0.0 lytB 3.5.1.28 D Stage II sporulation protein
LMMEADAK_03424 5.9e-49
LMMEADAK_03425 1.7e-149 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
LMMEADAK_03426 5.6e-119 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_03427 1.1e-40 L transposase activity
LMMEADAK_03428 3.7e-210 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
LMMEADAK_03429 2.8e-165 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LMMEADAK_03430 5.8e-283 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LMMEADAK_03431 1.7e-151 tagG GM Transport permease protein
LMMEADAK_03432 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LMMEADAK_03433 3.6e-293 M Glycosyltransferase like family 2
LMMEADAK_03434 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
LMMEADAK_03435 2.6e-143 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
LMMEADAK_03436 1.2e-219 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LMMEADAK_03437 6.5e-242 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
LMMEADAK_03438 8.7e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
LMMEADAK_03439 9.7e-264 gerBA EG Spore germination protein
LMMEADAK_03440 6.6e-196 gerBB E Spore germination protein
LMMEADAK_03441 1.4e-214 gerAC S Spore germination protein
LMMEADAK_03442 4.7e-268 GT2,GT4 J Glycosyl transferase family 2
LMMEADAK_03443 3.7e-249 ywtG EGP Major facilitator Superfamily
LMMEADAK_03444 3.8e-179 ywtF K Transcriptional regulator
LMMEADAK_03445 6.5e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
LMMEADAK_03446 7e-37 yttA 2.7.13.3 S Pfam Transposase IS66
LMMEADAK_03447 4.4e-241 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
LMMEADAK_03448 1.3e-20 ywtC
LMMEADAK_03449 2.6e-219 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
LMMEADAK_03450 2.3e-70 pgsC S biosynthesis protein
LMMEADAK_03451 1.8e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
LMMEADAK_03452 5e-183 gerKA EG Spore germination protein
LMMEADAK_03453 4.1e-190 gerKB E Spore germination protein
LMMEADAK_03454 2.1e-205 gerKC S Spore germination B3/ GerAC like, C-terminal
LMMEADAK_03455 1e-179 rbsR K transcriptional
LMMEADAK_03456 3e-159 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LMMEADAK_03457 9.6e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
LMMEADAK_03458 5.8e-280 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
LMMEADAK_03459 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
LMMEADAK_03460 2e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
LMMEADAK_03461 2.6e-89 batE T Sh3 type 3 domain protein
LMMEADAK_03462 2.8e-96 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
LMMEADAK_03463 7.9e-148 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
LMMEADAK_03464 3.4e-308 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LMMEADAK_03465 2e-166 alsR K LysR substrate binding domain
LMMEADAK_03466 1.2e-241 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LMMEADAK_03467 4.4e-126 ywrJ
LMMEADAK_03468 1.5e-129 cotB
LMMEADAK_03469 5e-212 cotH M Spore Coat
LMMEADAK_03470 2.2e-09
LMMEADAK_03471 3.3e-112 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LMMEADAK_03472 6.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
LMMEADAK_03473 1.1e-83 ywrC K Transcriptional regulator
LMMEADAK_03474 3.9e-102 ywrB P Chromate transporter
LMMEADAK_03475 1.7e-88 ywrA P COG2059 Chromate transport protein ChrA
LMMEADAK_03476 4.6e-134 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
LMMEADAK_03477 1.6e-93
LMMEADAK_03478 3.3e-66 S SMI1 / KNR4 family (SUKH-1)
LMMEADAK_03479 1.1e-103 S Domain of unknown function (DUF1851)
LMMEADAK_03480 1.6e-261 ywqJ S Pre-toxin TG
LMMEADAK_03481 9.5e-37 ywqI S Family of unknown function (DUF5344)
LMMEADAK_03482 8.5e-22 S Domain of unknown function (DUF5082)
LMMEADAK_03484 4.8e-148 ywqG S Domain of unknown function (DUF1963)
LMMEADAK_03485 1.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LMMEADAK_03486 3.5e-140 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
LMMEADAK_03487 4.3e-121 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
LMMEADAK_03488 5.2e-112 ywqC M biosynthesis protein
LMMEADAK_03489 1.3e-14
LMMEADAK_03490 7.8e-307 ywqB S SWIM zinc finger
LMMEADAK_03491 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
LMMEADAK_03492 2.3e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
LMMEADAK_03493 1.7e-134 glcR K DeoR C terminal sensor domain
LMMEADAK_03494 1.7e-57 ssbB L Single-stranded DNA-binding protein
LMMEADAK_03495 4e-62 ywpG
LMMEADAK_03496 1.1e-68 ywpF S YwpF-like protein
LMMEADAK_03497 1.4e-47 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
LMMEADAK_03498 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LMMEADAK_03499 2.9e-201 S aspartate phosphatase
LMMEADAK_03500 1.4e-145 flhP N flagellar basal body
LMMEADAK_03501 3.2e-128 flhO N flagellar basal body
LMMEADAK_03502 2.7e-180 mbl D Rod shape-determining protein
LMMEADAK_03503 1.8e-44 spoIIID K Stage III sporulation protein D
LMMEADAK_03504 8.5e-72 ywoH K transcriptional
LMMEADAK_03505 3.8e-213 ywoG EGP Major facilitator Superfamily
LMMEADAK_03506 1.4e-275 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
LMMEADAK_03507 1.8e-243 ywoD EGP Major facilitator superfamily
LMMEADAK_03508 2.8e-102 phzA Q Isochorismatase family
LMMEADAK_03509 1.6e-227 amt P Ammonium transporter
LMMEADAK_03510 2e-58 nrgB K Belongs to the P(II) protein family
LMMEADAK_03511 2.4e-209 ftsW D Belongs to the SEDS family
LMMEADAK_03512 5.4e-101 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
LMMEADAK_03513 5.1e-72 ywnJ S VanZ like family
LMMEADAK_03514 4.9e-122 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
LMMEADAK_03515 2.4e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
LMMEADAK_03516 1.2e-10 ywnC S Family of unknown function (DUF5362)
LMMEADAK_03517 4.2e-69 ywnF S Family of unknown function (DUF5392)
LMMEADAK_03518 8.4e-276 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LMMEADAK_03519 4.4e-54 ywnC S Family of unknown function (DUF5362)
LMMEADAK_03520 9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
LMMEADAK_03521 6.1e-67 ywnA K Transcriptional regulator
LMMEADAK_03522 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LMMEADAK_03523 3.8e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LMMEADAK_03524 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LMMEADAK_03525 6.5e-11 csbD K CsbD-like
LMMEADAK_03526 2.1e-82 ywmF S Peptidase M50
LMMEADAK_03527 4.8e-93 S response regulator aspartate phosphatase
LMMEADAK_03528 5.3e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LMMEADAK_03529 3.2e-144 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LMMEADAK_03531 3e-122 ywmD S protein containing a von Willebrand factor type A (vWA) domain
LMMEADAK_03532 1.2e-123 ywmC S protein containing a von Willebrand factor type A (vWA) domain
LMMEADAK_03533 1.9e-189 spoIID D Stage II sporulation protein D
LMMEADAK_03534 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LMMEADAK_03535 9e-133 ywmB S TATA-box binding
LMMEADAK_03536 4.1e-31 ywzB S membrane
LMMEADAK_03537 7.9e-90 ywmA
LMMEADAK_03538 1.8e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LMMEADAK_03539 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LMMEADAK_03540 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LMMEADAK_03541 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LMMEADAK_03542 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LMMEADAK_03543 1.3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LMMEADAK_03544 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LMMEADAK_03545 2.1e-129 atpB C it plays a direct role in the translocation of protons across the membrane
LMMEADAK_03546 2.1e-61 atpI S ATP synthase
LMMEADAK_03547 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LMMEADAK_03548 3.5e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LMMEADAK_03549 5.9e-97 ywlG S Belongs to the UPF0340 family
LMMEADAK_03550 1.1e-80 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
LMMEADAK_03551 1.1e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LMMEADAK_03552 1.2e-84 mntP P Probably functions as a manganese efflux pump
LMMEADAK_03553 1e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LMMEADAK_03554 3.6e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
LMMEADAK_03555 8.9e-119 spoIIR S stage II sporulation protein R
LMMEADAK_03556 1.4e-60 ywlA S Uncharacterised protein family (UPF0715)
LMMEADAK_03558 1.6e-157 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LMMEADAK_03559 1.9e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LMMEADAK_03560 6.9e-68 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LMMEADAK_03561 3.3e-95 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
LMMEADAK_03562 3.6e-158 ywkB S Membrane transport protein
LMMEADAK_03563 0.0 sfcA 1.1.1.38 C malic enzyme
LMMEADAK_03564 4.1e-104 tdk 2.7.1.21 F thymidine kinase
LMMEADAK_03565 1.1e-32 rpmE J Binds the 23S rRNA
LMMEADAK_03566 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LMMEADAK_03567 5.6e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
LMMEADAK_03568 6.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LMMEADAK_03569 3.2e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LMMEADAK_03570 5.5e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
LMMEADAK_03571 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
LMMEADAK_03572 1.7e-93 ywjG S Domain of unknown function (DUF2529)
LMMEADAK_03573 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LMMEADAK_03574 2.2e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LMMEADAK_03575 0.0 fadF C COG0247 Fe-S oxidoreductase
LMMEADAK_03576 1.6e-219 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
LMMEADAK_03577 2.3e-181 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
LMMEADAK_03578 4.2e-43 ywjC
LMMEADAK_03579 0.0 ywjA V ABC transporter
LMMEADAK_03580 3.1e-300 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LMMEADAK_03581 1.4e-105 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LMMEADAK_03582 9.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
LMMEADAK_03583 3.5e-97 narJ 1.7.5.1 C nitrate reductase
LMMEADAK_03584 8.2e-295 narH 1.7.5.1 C Nitrate reductase, beta
LMMEADAK_03585 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LMMEADAK_03586 2e-85 arfM T cyclic nucleotide binding
LMMEADAK_03587 2.2e-139 ywiC S YwiC-like protein
LMMEADAK_03588 4.5e-129 fnr K helix_turn_helix, cAMP Regulatory protein
LMMEADAK_03589 4.9e-213 narK P COG2223 Nitrate nitrite transporter
LMMEADAK_03590 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
LMMEADAK_03591 1.2e-73 ywiB S protein conserved in bacteria
LMMEADAK_03593 7.3e-229 ywhL CO amine dehydrogenase activity
LMMEADAK_03594 3.8e-222 ywhK CO amine dehydrogenase activity
LMMEADAK_03595 3.2e-76 S aspartate phosphatase
LMMEADAK_03597 2.6e-29 ydcG K sequence-specific DNA binding
LMMEADAK_03598 5e-33
LMMEADAK_03599 2.2e-27 S Domain of unknown function (DUF4177)
LMMEADAK_03601 1.1e-76 CP Membrane
LMMEADAK_03604 5.4e-169 speB 3.5.3.11 E Belongs to the arginase family
LMMEADAK_03605 4.1e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LMMEADAK_03606 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LMMEADAK_03607 1.5e-82
LMMEADAK_03608 1.4e-95 ywhD S YwhD family
LMMEADAK_03609 1.1e-118 ywhC S Peptidase family M50
LMMEADAK_03610 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
LMMEADAK_03611 3.6e-70 ywhA K Transcriptional regulator
LMMEADAK_03612 1.6e-247 yhdG_1 E C-terminus of AA_permease
LMMEADAK_03613 9.2e-89 ywgA 2.1.1.72, 3.1.21.3
LMMEADAK_03614 3e-256 ywfO S COG1078 HD superfamily phosphohydrolases
LMMEADAK_03615 6.9e-36 ywzC S Belongs to the UPF0741 family
LMMEADAK_03616 6.6e-110 rsfA_1
LMMEADAK_03617 8.2e-51 padR K PadR family transcriptional regulator
LMMEADAK_03618 8.1e-94 S membrane
LMMEADAK_03619 3.5e-166 V ABC transporter, ATP-binding protein
LMMEADAK_03620 1.3e-168 yhcI S ABC transporter (permease)
LMMEADAK_03623 1.1e-177
LMMEADAK_03625 2.3e-159 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
LMMEADAK_03626 3.9e-162 cysL K Transcriptional regulator
LMMEADAK_03627 5.3e-157 MA20_14895 S Conserved hypothetical protein 698
LMMEADAK_03628 5.1e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
LMMEADAK_03629 1.1e-146 ywfI C May function as heme-dependent peroxidase
LMMEADAK_03630 7.5e-141 IQ Enoyl-(Acyl carrier protein) reductase
LMMEADAK_03631 7.8e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
LMMEADAK_03632 4.7e-208 bacE EGP Major facilitator Superfamily
LMMEADAK_03633 1.4e-267 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
LMMEADAK_03634 7.8e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
LMMEADAK_03635 1.5e-137 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
LMMEADAK_03636 1.1e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
LMMEADAK_03637 5.8e-225 ywfA EGP Major facilitator Superfamily
LMMEADAK_03638 9.6e-209 tcaB EGP Major facilitator Superfamily
LMMEADAK_03639 1.7e-260 lysP E amino acid
LMMEADAK_03640 0.0 rocB E arginine degradation protein
LMMEADAK_03641 7.8e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
LMMEADAK_03642 2.5e-247 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
LMMEADAK_03643 7.1e-59
LMMEADAK_03644 3.5e-87 spsL 5.1.3.13 M Spore Coat
LMMEADAK_03645 5.8e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LMMEADAK_03646 9.3e-183 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LMMEADAK_03647 1e-136 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LMMEADAK_03648 8.9e-184 spsG M Spore Coat
LMMEADAK_03649 3.1e-133 spsF M Spore Coat
LMMEADAK_03650 3.4e-216 spsE 2.5.1.56 M acid synthase
LMMEADAK_03651 7.7e-160 spsD 2.3.1.210 K Spore Coat
LMMEADAK_03652 8.7e-223 spsC E Belongs to the DegT DnrJ EryC1 family
LMMEADAK_03653 2e-274 spsB M Capsule polysaccharide biosynthesis protein
LMMEADAK_03654 2.6e-143 spsA M Spore Coat
LMMEADAK_03655 1e-64 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
LMMEADAK_03656 4.2e-46 ywdK S small membrane protein
LMMEADAK_03657 2.9e-230 ywdJ F Xanthine uracil
LMMEADAK_03658 1.6e-40 ywdI S Family of unknown function (DUF5327)
LMMEADAK_03659 1.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LMMEADAK_03660 5e-153 ywdF GT2,GT4 S Glycosyltransferase like family 2
LMMEADAK_03662 2.6e-88 ywdD
LMMEADAK_03663 6.3e-57 pex K Transcriptional regulator PadR-like family
LMMEADAK_03664 6e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
LMMEADAK_03665 9.7e-20 ywdA
LMMEADAK_03666 8.6e-289 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
LMMEADAK_03667 3.6e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LMMEADAK_03668 8.3e-151 sacT K transcriptional antiterminator
LMMEADAK_03670 0.0 vpr O Belongs to the peptidase S8 family
LMMEADAK_03671 4.4e-183 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LMMEADAK_03672 2.7e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
LMMEADAK_03673 4.7e-208 rodA D Belongs to the SEDS family
LMMEADAK_03674 6.9e-79 ysnE K acetyltransferase
LMMEADAK_03675 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
LMMEADAK_03676 2e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LMMEADAK_03677 8.1e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
LMMEADAK_03678 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LMMEADAK_03679 8.3e-179 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
LMMEADAK_03680 8.4e-27 ywzA S membrane
LMMEADAK_03681 3.4e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
LMMEADAK_03682 2.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LMMEADAK_03683 9.3e-63 gtcA S GtrA-like protein
LMMEADAK_03684 1.3e-111 ywcC K Bacterial regulatory proteins, tetR family
LMMEADAK_03686 3.1e-127 H Methionine biosynthesis protein MetW
LMMEADAK_03687 8.2e-133 S Streptomycin biosynthesis protein StrF
LMMEADAK_03688 4.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
LMMEADAK_03689 4.8e-243 ywbN P Dyp-type peroxidase family protein
LMMEADAK_03690 6.6e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
LMMEADAK_03691 4.3e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LMMEADAK_03692 8.2e-152 ywbI K Transcriptional regulator
LMMEADAK_03693 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
LMMEADAK_03694 1.5e-110 ywbG M effector of murein hydrolase
LMMEADAK_03695 1.8e-27 ywbE S Uncharacterized conserved protein (DUF2196)
LMMEADAK_03696 3.2e-141 mta K transcriptional
LMMEADAK_03697 1.1e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
LMMEADAK_03698 2.7e-224 ywbD 2.1.1.191 J Methyltransferase
LMMEADAK_03699 7.6e-67 ywbC 4.4.1.5 E glyoxalase
LMMEADAK_03700 2.4e-245 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LMMEADAK_03701 3.9e-267 epr 3.4.21.62 O Belongs to the peptidase S8 family
LMMEADAK_03702 3.3e-163 gspA M General stress
LMMEADAK_03703 7.8e-117 ywaC 2.7.6.5 S protein conserved in bacteria
LMMEADAK_03704 1.3e-168 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
LMMEADAK_03705 3e-11 S D-Ala-teichoic acid biosynthesis protein
LMMEADAK_03706 1.3e-292 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_03707 3.7e-229 dltB M membrane protein involved in D-alanine export
LMMEADAK_03708 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LMMEADAK_03709 3.1e-228 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LMMEADAK_03710 7.6e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
LMMEADAK_03711 1.2e-252 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
LMMEADAK_03712 1.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
LMMEADAK_03713 2.2e-249 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LMMEADAK_03714 1.2e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
LMMEADAK_03715 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
LMMEADAK_03716 6.6e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
LMMEADAK_03717 1.2e-172 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_03718 6.1e-180 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LMMEADAK_03719 4e-167 cbrA3 P Periplasmic binding protein
LMMEADAK_03720 1.4e-59 arsR K transcriptional
LMMEADAK_03721 2.9e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LMMEADAK_03722 2.2e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
LMMEADAK_03723 4.1e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
LMMEADAK_03724 8.3e-230 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LMMEADAK_03725 3.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LMMEADAK_03726 1.9e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
LMMEADAK_03727 5.1e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
LMMEADAK_03728 4.2e-211 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
LMMEADAK_03729 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
LMMEADAK_03730 3.6e-193 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
LMMEADAK_03731 1.2e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
LMMEADAK_03732 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LMMEADAK_03733 4.5e-292 cydD V ATP-binding protein
LMMEADAK_03734 0.0 cydD V ATP-binding
LMMEADAK_03735 5.5e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
LMMEADAK_03736 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
LMMEADAK_03737 1.1e-213 cimH C COG3493 Na citrate symporter
LMMEADAK_03738 3.5e-157 yxkH G Polysaccharide deacetylase
LMMEADAK_03739 2.8e-205 msmK P Belongs to the ABC transporter superfamily
LMMEADAK_03740 1e-167 lrp QT PucR C-terminal helix-turn-helix domain
LMMEADAK_03741 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
LMMEADAK_03742 4.2e-86 yxkC S Domain of unknown function (DUF4352)
LMMEADAK_03743 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LMMEADAK_03744 2.3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LMMEADAK_03747 1.2e-69 yxjI S LURP-one-related
LMMEADAK_03748 7.4e-219 yxjG 2.1.1.14 E Methionine synthase
LMMEADAK_03749 2.5e-158 rlmA 2.1.1.187 Q Methyltransferase domain
LMMEADAK_03750 4.6e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LMMEADAK_03751 1.6e-72 T Domain of unknown function (DUF4163)
LMMEADAK_03752 3.7e-48 yxiS
LMMEADAK_03754 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
LMMEADAK_03755 6.2e-222 citH C Citrate transporter
LMMEADAK_03756 2.1e-142 exoK GH16 M licheninase activity
LMMEADAK_03757 7e-150 licT K transcriptional antiterminator
LMMEADAK_03758 5.4e-223 yxiO S COG2270 Permeases of the major facilitator superfamily
LMMEADAK_03759 1.2e-261 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
LMMEADAK_03762 7.3e-59 S SMI1-KNR4 cell-wall
LMMEADAK_03763 1.1e-80 yxiI S Protein of unknown function (DUF2716)
LMMEADAK_03765 4.6e-21
LMMEADAK_03766 1.8e-15 S YxiJ-like protein
LMMEADAK_03770 4.6e-70 yxiG
LMMEADAK_03771 2.5e-68 yxxG
LMMEADAK_03774 2.7e-202 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
LMMEADAK_03775 2.1e-147 yxxF EG EamA-like transporter family
LMMEADAK_03776 1.7e-73 yxiE T Belongs to the universal stress protein A family
LMMEADAK_03777 2.4e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LMMEADAK_03778 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
LMMEADAK_03779 0.0 L HKD family nuclease
LMMEADAK_03780 1.2e-64 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
LMMEADAK_03781 1.6e-279 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
LMMEADAK_03782 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
LMMEADAK_03783 5.6e-286 hutH 4.3.1.3 E Histidine ammonia-lyase
LMMEADAK_03784 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LMMEADAK_03785 1.9e-239 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
LMMEADAK_03786 1.3e-176 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
LMMEADAK_03787 2e-253 lysP E amino acid
LMMEADAK_03788 1.3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
LMMEADAK_03789 2.3e-207 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LMMEADAK_03790 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LMMEADAK_03791 1.1e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
LMMEADAK_03792 4e-150 yidA S hydrolases of the HAD superfamily
LMMEADAK_03795 6.4e-13 yxeE
LMMEADAK_03796 8.4e-23 yxeD
LMMEADAK_03797 6e-35
LMMEADAK_03798 9.2e-178 fhuD P Periplasmic binding protein
LMMEADAK_03799 7.6e-58 yxeA S Protein of unknown function (DUF1093)
LMMEADAK_03800 0.0 yxdM V ABC transporter (permease)
LMMEADAK_03801 5.5e-141 yxdL V ABC transporter, ATP-binding protein
LMMEADAK_03802 3.8e-179 T PhoQ Sensor
LMMEADAK_03803 8.4e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_03804 8.4e-276 T Histidine kinase
LMMEADAK_03805 5.3e-138 T Transcriptional regulator
LMMEADAK_03806 1e-162 bcrA V ABC transporter, ATP-binding protein
LMMEADAK_03807 2.3e-131 S permease
LMMEADAK_03808 9.3e-130 S ABC-2 family transporter protein
LMMEADAK_03809 9.2e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
LMMEADAK_03810 1.9e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
LMMEADAK_03811 1.1e-166 iolH G Xylose isomerase-like TIM barrel
LMMEADAK_03812 9.5e-197 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
LMMEADAK_03813 6e-233 iolF EGP Major facilitator Superfamily
LMMEADAK_03814 2.7e-176 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
LMMEADAK_03815 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
LMMEADAK_03816 5.7e-183 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
LMMEADAK_03817 5.8e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
LMMEADAK_03818 6.1e-282 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
LMMEADAK_03819 3.1e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
LMMEADAK_03820 4.9e-176 iolS C Aldo keto reductase
LMMEADAK_03821 1.2e-44 L COG2963 Transposase and inactivated derivatives
LMMEADAK_03822 5.7e-141 L Molecular Function DNA binding, Biological Process DNA recombination
LMMEADAK_03823 1.9e-245 csbC EGP Major facilitator Superfamily
LMMEADAK_03824 0.0 htpG O Molecular chaperone. Has ATPase activity
LMMEADAK_03826 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
LMMEADAK_03827 2.5e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LMMEADAK_03828 8.2e-202 desK 2.7.13.3 T Histidine kinase
LMMEADAK_03829 1.5e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
LMMEADAK_03830 3.5e-216 yxbF K Bacterial regulatory proteins, tetR family
LMMEADAK_03831 2.5e-250 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
LMMEADAK_03832 3.4e-140 S PQQ-like domain
LMMEADAK_03833 6e-65 S Family of unknown function (DUF5391)
LMMEADAK_03834 7.8e-51 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
LMMEADAK_03835 1.4e-204 EGP Major facilitator Superfamily
LMMEADAK_03836 1.5e-74 yxaI S membrane protein domain
LMMEADAK_03837 3.1e-127 E Ring-cleavage extradiol dioxygenase
LMMEADAK_03838 3.2e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
LMMEADAK_03839 2.3e-287 ahpF O Alkyl hydroperoxide reductase
LMMEADAK_03840 5.4e-231 XK27_00240 S Fic/DOC family
LMMEADAK_03841 6.5e-246 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
LMMEADAK_03842 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
LMMEADAK_03843 3e-86 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
LMMEADAK_03844 1.7e-156 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
LMMEADAK_03845 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
LMMEADAK_03846 1.4e-91 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
LMMEADAK_03847 3.9e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LMMEADAK_03848 1.5e-183 S Fusaric acid resistance protein-like
LMMEADAK_03849 1.3e-125 S AAA domain, putative AbiEii toxin, Type IV TA system
LMMEADAK_03851 2.6e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LMMEADAK_03852 7.9e-08 S YyzF-like protein
LMMEADAK_03855 7.2e-217 yycP
LMMEADAK_03856 4.5e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
LMMEADAK_03857 2.1e-185 C oxidoreductases (related to aryl-alcohol dehydrogenases)
LMMEADAK_03858 1.1e-86 yycN 2.3.1.128 K Acetyltransferase
LMMEADAK_03860 4.7e-202 S Histidine kinase
LMMEADAK_03861 1.8e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
LMMEADAK_03862 2.6e-258 rocE E amino acid
LMMEADAK_03863 4.6e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
LMMEADAK_03864 1.4e-62 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
LMMEADAK_03865 2.2e-42 sdpR K transcriptional
LMMEADAK_03866 9.8e-261 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
LMMEADAK_03867 5.3e-146 1.14.11.27 P peptidyl-arginine hydroxylation
LMMEADAK_03868 3.9e-306 S ABC transporter
LMMEADAK_03869 2.6e-198 S Major Facilitator Superfamily
LMMEADAK_03870 2.4e-261
LMMEADAK_03871 1.1e-192 2.7.7.73, 2.7.7.80 H ThiF family
LMMEADAK_03872 4.1e-251 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
LMMEADAK_03873 1.6e-10 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_03874 1.2e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LMMEADAK_03875 1.8e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
LMMEADAK_03876 4.4e-152 yycI S protein conserved in bacteria
LMMEADAK_03877 2.1e-260 yycH S protein conserved in bacteria
LMMEADAK_03878 0.0 vicK 2.7.13.3 T Histidine kinase
LMMEADAK_03879 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LMMEADAK_03884 1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LMMEADAK_03885 1.4e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LMMEADAK_03886 2.8e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LMMEADAK_03887 8e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
LMMEADAK_03889 3.5e-17 yycC K YycC-like protein
LMMEADAK_03890 2.7e-241 M Glycosyltransferase Family 4
LMMEADAK_03891 1.9e-205 S Ecdysteroid kinase
LMMEADAK_03892 9.1e-236 S Carbamoyl-phosphate synthase L chain, ATP binding domain
LMMEADAK_03893 1.2e-236 M Glycosyltransferase Family 4
LMMEADAK_03894 2.7e-120 S GlcNAc-PI de-N-acetylase
LMMEADAK_03895 7.2e-90 KLT COG0515 Serine threonine protein kinase
LMMEADAK_03896 4.9e-73 rplI J binds to the 23S rRNA
LMMEADAK_03897 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LMMEADAK_03898 1.6e-158 yybS S membrane
LMMEADAK_03900 6.5e-85 cotF M Spore coat protein
LMMEADAK_03901 2.8e-66 ydeP3 K Transcriptional regulator
LMMEADAK_03902 1.7e-165 ppaC 3.6.1.1 C Inorganic pyrophosphatase
LMMEADAK_03903 4.8e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LMMEADAK_03904 2.2e-273 sacB 2.4.1.10 GH68 M levansucrase activity
LMMEADAK_03905 2.2e-311 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
LMMEADAK_03906 1.8e-116 K FCD domain
LMMEADAK_03907 4.1e-76 dinB S PFAM DinB family protein
LMMEADAK_03908 7.6e-161 G Major Facilitator Superfamily
LMMEADAK_03909 4.2e-14 comA K response regulator
LMMEADAK_03910 5.7e-244 trpE 2.6.1.85, 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LMMEADAK_03911 4.8e-78 eamA1 EG spore germination
LMMEADAK_03912 4.9e-77 H porphobilinogen synthase activity
LMMEADAK_03913 2.2e-162 yfiE K LysR substrate binding domain
LMMEADAK_03914 3.3e-100 E LysE type translocator
LMMEADAK_03915 1.4e-54 ypaA S Protein of unknown function (DUF1304)
LMMEADAK_03916 5.6e-115 drgA C nitroreductase
LMMEADAK_03917 5.4e-69 ydgJ K Winged helix DNA-binding domain
LMMEADAK_03918 3.3e-150 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
LMMEADAK_03919 4.3e-77 yybA 2.3.1.57 K transcriptional
LMMEADAK_03920 2.7e-76 yjcF S Acetyltransferase (GNAT) domain
LMMEADAK_03921 3.4e-163 eaeH M Domain of Unknown Function (DUF1259)
LMMEADAK_03922 2.1e-67 4.1.1.44 S Carboxymuconolactone decarboxylase family
LMMEADAK_03923 4.5e-166 K Transcriptional regulator
LMMEADAK_03924 8e-143 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
LMMEADAK_03925 4.1e-246 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LMMEADAK_03926 2.3e-130 ydfC EG EamA-like transporter family
LMMEADAK_03927 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
LMMEADAK_03928 2.4e-164 yyaK S CAAX protease self-immunity
LMMEADAK_03929 6.2e-249 ydjK G Sugar (and other) transporter
LMMEADAK_03930 8.9e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
LMMEADAK_03931 4.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
LMMEADAK_03932 5.2e-144 xth 3.1.11.2 L exodeoxyribonuclease III
LMMEADAK_03933 2.2e-99 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LMMEADAK_03934 7.4e-106 adaA 3.2.2.21 K Transcriptional regulator
LMMEADAK_03935 1.1e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LMMEADAK_03936 3.8e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LMMEADAK_03937 7.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
LMMEADAK_03938 3.7e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LMMEADAK_03939 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
LMMEADAK_03940 2.3e-33 yyzM S protein conserved in bacteria
LMMEADAK_03941 2.4e-176 yyaD S Membrane
LMMEADAK_03942 8.1e-68 4.2.1.103 K FR47-like protein
LMMEADAK_03943 6.2e-111 yyaC S Sporulation protein YyaC
LMMEADAK_03944 3e-148 spo0J K Belongs to the ParB family
LMMEADAK_03945 1.2e-135 soj D COG1192 ATPases involved in chromosome partitioning
LMMEADAK_03946 1.3e-151 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
LMMEADAK_03947 4.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
LMMEADAK_03948 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LMMEADAK_03949 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LMMEADAK_03950 1.4e-110 jag S single-stranded nucleic acid binding R3H
LMMEADAK_03951 1.9e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LMMEADAK_03952 5.2e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)