ORF_ID e_value Gene_name EC_number CAZy COGs Description
COHLBPCN_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COHLBPCN_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COHLBPCN_00003 2.4e-33 yaaA S S4 domain
COHLBPCN_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COHLBPCN_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
COHLBPCN_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COHLBPCN_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COHLBPCN_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00011 2.7e-182 yaaC S YaaC-like Protein
COHLBPCN_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
COHLBPCN_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COHLBPCN_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
COHLBPCN_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
COHLBPCN_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COHLBPCN_00017 1.3e-09
COHLBPCN_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
COHLBPCN_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
COHLBPCN_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
COHLBPCN_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
COHLBPCN_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COHLBPCN_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COHLBPCN_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COHLBPCN_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COHLBPCN_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
COHLBPCN_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
COHLBPCN_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
COHLBPCN_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
COHLBPCN_00033 4.5e-203 yaaN P Belongs to the TelA family
COHLBPCN_00034 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
COHLBPCN_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COHLBPCN_00036 2.2e-54 yaaQ S protein conserved in bacteria
COHLBPCN_00037 1.5e-71 yaaR S protein conserved in bacteria
COHLBPCN_00038 2.2e-182 holB 2.7.7.7 L DNA polymerase III
COHLBPCN_00039 2.1e-146 yaaT S stage 0 sporulation protein
COHLBPCN_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
COHLBPCN_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
COHLBPCN_00042 1.5e-49 yazA L endonuclease containing a URI domain
COHLBPCN_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COHLBPCN_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
COHLBPCN_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COHLBPCN_00046 1.8e-144 tatD L hydrolase, TatD
COHLBPCN_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
COHLBPCN_00048 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COHLBPCN_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COHLBPCN_00050 3.3e-137 yabG S peptidase
COHLBPCN_00051 7.8e-39 veg S protein conserved in bacteria
COHLBPCN_00052 8.3e-27 sspF S DNA topological change
COHLBPCN_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COHLBPCN_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
COHLBPCN_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
COHLBPCN_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
COHLBPCN_00057 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COHLBPCN_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COHLBPCN_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
COHLBPCN_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COHLBPCN_00061 2.4e-39 yabK S Peptide ABC transporter permease
COHLBPCN_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COHLBPCN_00063 1.5e-92 spoVT K stage V sporulation protein
COHLBPCN_00064 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COHLBPCN_00065 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
COHLBPCN_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
COHLBPCN_00067 1.5e-49 yabP S Sporulation protein YabP
COHLBPCN_00068 3.9e-108 yabQ S spore cortex biosynthesis protein
COHLBPCN_00069 1.1e-44 divIC D Septum formation initiator
COHLBPCN_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
COHLBPCN_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
COHLBPCN_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
COHLBPCN_00075 6.7e-187 KLT serine threonine protein kinase
COHLBPCN_00076 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COHLBPCN_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COHLBPCN_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COHLBPCN_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
COHLBPCN_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COHLBPCN_00081 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
COHLBPCN_00082 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COHLBPCN_00083 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COHLBPCN_00084 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
COHLBPCN_00085 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
COHLBPCN_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
COHLBPCN_00087 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COHLBPCN_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
COHLBPCN_00089 4.1e-30 yazB K transcriptional
COHLBPCN_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COHLBPCN_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COHLBPCN_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00097 2e-08
COHLBPCN_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00103 2.9e-76 ctsR K Belongs to the CtsR family
COHLBPCN_00104 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
COHLBPCN_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
COHLBPCN_00106 0.0 clpC O Belongs to the ClpA ClpB family
COHLBPCN_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COHLBPCN_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
COHLBPCN_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
COHLBPCN_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
COHLBPCN_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
COHLBPCN_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COHLBPCN_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
COHLBPCN_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COHLBPCN_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COHLBPCN_00116 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COHLBPCN_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
COHLBPCN_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
COHLBPCN_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COHLBPCN_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
COHLBPCN_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COHLBPCN_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COHLBPCN_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COHLBPCN_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COHLBPCN_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
COHLBPCN_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COHLBPCN_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COHLBPCN_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
COHLBPCN_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COHLBPCN_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COHLBPCN_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COHLBPCN_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COHLBPCN_00133 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
COHLBPCN_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COHLBPCN_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COHLBPCN_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
COHLBPCN_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COHLBPCN_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COHLBPCN_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COHLBPCN_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COHLBPCN_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COHLBPCN_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COHLBPCN_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
COHLBPCN_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COHLBPCN_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COHLBPCN_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COHLBPCN_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COHLBPCN_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COHLBPCN_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COHLBPCN_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COHLBPCN_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COHLBPCN_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COHLBPCN_00153 1.9e-23 rpmD J Ribosomal protein L30
COHLBPCN_00154 1.8e-72 rplO J binds to the 23S rRNA
COHLBPCN_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COHLBPCN_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COHLBPCN_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
COHLBPCN_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COHLBPCN_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COHLBPCN_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COHLBPCN_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COHLBPCN_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COHLBPCN_00163 3.6e-58 rplQ J Ribosomal protein L17
COHLBPCN_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COHLBPCN_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COHLBPCN_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COHLBPCN_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COHLBPCN_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COHLBPCN_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
COHLBPCN_00170 8.2e-145 ybaJ Q Methyltransferase domain
COHLBPCN_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
COHLBPCN_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COHLBPCN_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
COHLBPCN_00174 1.2e-84 gerD
COHLBPCN_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
COHLBPCN_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
COHLBPCN_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00180 2e-08
COHLBPCN_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00186 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
COHLBPCN_00188 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
COHLBPCN_00189 2.2e-142 ybbA S Putative esterase
COHLBPCN_00190 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_00191 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_00192 7.2e-167 feuA P Iron-uptake system-binding protein
COHLBPCN_00193 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
COHLBPCN_00194 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
COHLBPCN_00195 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
COHLBPCN_00196 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
COHLBPCN_00197 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COHLBPCN_00198 1.1e-150 ybbH K transcriptional
COHLBPCN_00199 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
COHLBPCN_00200 6.4e-87 ybbJ J acetyltransferase
COHLBPCN_00201 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
COHLBPCN_00207 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_00208 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
COHLBPCN_00209 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COHLBPCN_00210 3e-225 ybbR S protein conserved in bacteria
COHLBPCN_00211 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COHLBPCN_00212 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COHLBPCN_00213 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
COHLBPCN_00214 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
COHLBPCN_00215 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COHLBPCN_00216 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
COHLBPCN_00217 0.0 ybcC S Belongs to the UPF0753 family
COHLBPCN_00218 3.7e-96 can 4.2.1.1 P carbonic anhydrase
COHLBPCN_00219 3.9e-47
COHLBPCN_00220 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
COHLBPCN_00221 5.1e-50 ybzH K Helix-turn-helix domain
COHLBPCN_00222 2e-203 ybcL EGP Major facilitator Superfamily
COHLBPCN_00224 9.1e-239 J 4Fe-4S single cluster domain
COHLBPCN_00225 1.6e-277 V CAAX protease self-immunity
COHLBPCN_00226 1.9e-135 skfE V ABC transporter
COHLBPCN_00227 4e-248 skfF S ABC transporter
COHLBPCN_00228 7.8e-91 C HEAT repeats
COHLBPCN_00229 9.6e-79 txn CO Thioredoxin-like
COHLBPCN_00230 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COHLBPCN_00231 1.5e-123 T Transcriptional regulatory protein, C terminal
COHLBPCN_00232 1.8e-173 T His Kinase A (phospho-acceptor) domain
COHLBPCN_00234 1.6e-140 KLT Protein tyrosine kinase
COHLBPCN_00235 4.8e-154 ybdN
COHLBPCN_00236 1.5e-217 ybdO S Domain of unknown function (DUF4885)
COHLBPCN_00237 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
COHLBPCN_00238 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
COHLBPCN_00239 4.9e-30 ybxH S Family of unknown function (DUF5370)
COHLBPCN_00240 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
COHLBPCN_00241 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
COHLBPCN_00242 4.9e-41 ybyB
COHLBPCN_00243 2.3e-290 ybeC E amino acid
COHLBPCN_00244 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COHLBPCN_00245 7.3e-258 glpT G -transporter
COHLBPCN_00246 2.9e-35 S Protein of unknown function (DUF2651)
COHLBPCN_00247 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
COHLBPCN_00248 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
COHLBPCN_00250 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
COHLBPCN_00251 8.8e-162 ybfH EG EamA-like transporter family
COHLBPCN_00252 2.3e-145 msmR K AraC-like ligand binding domain
COHLBPCN_00253 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COHLBPCN_00254 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
COHLBPCN_00256 2.5e-169 S Alpha/beta hydrolase family
COHLBPCN_00257 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COHLBPCN_00258 2.7e-85 ybfM S SNARE associated Golgi protein
COHLBPCN_00259 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
COHLBPCN_00260 3.2e-46 ybfN
COHLBPCN_00261 3.6e-257 S Erythromycin esterase
COHLBPCN_00262 6.7e-167 ybfP K Transcriptional regulator
COHLBPCN_00263 3.9e-192 yceA S Belongs to the UPF0176 family
COHLBPCN_00264 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COHLBPCN_00265 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COHLBPCN_00266 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COHLBPCN_00267 4.9e-128 K UTRA
COHLBPCN_00269 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
COHLBPCN_00270 6.7e-262 mmuP E amino acid
COHLBPCN_00271 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
COHLBPCN_00272 2.3e-257 agcS E Sodium alanine symporter
COHLBPCN_00273 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
COHLBPCN_00274 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
COHLBPCN_00275 9e-170 glnL T Regulator
COHLBPCN_00276 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
COHLBPCN_00277 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COHLBPCN_00278 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
COHLBPCN_00279 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
COHLBPCN_00280 1.5e-124 ycbG K FCD
COHLBPCN_00281 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
COHLBPCN_00282 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
COHLBPCN_00283 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
COHLBPCN_00284 7.3e-172 eamA1 EG spore germination
COHLBPCN_00285 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_00286 2.4e-170 T PhoQ Sensor
COHLBPCN_00287 4.8e-168 ycbN V ABC transporter, ATP-binding protein
COHLBPCN_00288 2.1e-115 S ABC-2 family transporter protein
COHLBPCN_00289 8.2e-53 ycbP S Protein of unknown function (DUF2512)
COHLBPCN_00290 1.3e-78 sleB 3.5.1.28 M Cell wall
COHLBPCN_00291 6.6e-136 ycbR T vWA found in TerF C terminus
COHLBPCN_00292 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
COHLBPCN_00293 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
COHLBPCN_00294 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COHLBPCN_00295 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COHLBPCN_00296 6.2e-210 ycbU E Selenocysteine lyase
COHLBPCN_00297 5.8e-229 lmrB EGP the major facilitator superfamily
COHLBPCN_00298 4.8e-102 yxaF K Transcriptional regulator
COHLBPCN_00299 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
COHLBPCN_00300 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
COHLBPCN_00301 2e-59 S RDD family
COHLBPCN_00302 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
COHLBPCN_00303 2e-161 2.7.13.3 T GHKL domain
COHLBPCN_00304 1.2e-126 lytR_2 T LytTr DNA-binding domain
COHLBPCN_00305 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
COHLBPCN_00306 4.5e-203 natB CP ABC-2 family transporter protein
COHLBPCN_00307 1.6e-174 yccK C Aldo keto reductase
COHLBPCN_00308 6.6e-177 ycdA S Domain of unknown function (DUF5105)
COHLBPCN_00309 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_00310 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_00311 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
COHLBPCN_00312 5.5e-174 S response regulator aspartate phosphatase
COHLBPCN_00313 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
COHLBPCN_00314 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
COHLBPCN_00315 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
COHLBPCN_00316 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
COHLBPCN_00317 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
COHLBPCN_00318 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COHLBPCN_00319 7.3e-56 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
COHLBPCN_00320 8.7e-40 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
COHLBPCN_00321 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
COHLBPCN_00322 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
COHLBPCN_00323 6.3e-137 terC P Protein of unknown function (DUF475)
COHLBPCN_00324 0.0 yceG S Putative component of 'biosynthetic module'
COHLBPCN_00325 2e-192 yceH P Belongs to the TelA family
COHLBPCN_00326 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
COHLBPCN_00327 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
COHLBPCN_00328 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
COHLBPCN_00329 5.1e-229 proV 3.6.3.32 E glycine betaine
COHLBPCN_00330 1.3e-127 opuAB P glycine betaine
COHLBPCN_00331 5.3e-164 opuAC E glycine betaine
COHLBPCN_00332 1.2e-219 amhX S amidohydrolase
COHLBPCN_00333 1e-257 ycgA S Membrane
COHLBPCN_00334 1.1e-98 ycgB
COHLBPCN_00335 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
COHLBPCN_00336 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COHLBPCN_00337 6.5e-293 lctP C L-lactate permease
COHLBPCN_00338 6.2e-269 mdr EGP Major facilitator Superfamily
COHLBPCN_00339 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_00340 6.8e-113 ycgF E Lysine exporter protein LysE YggA
COHLBPCN_00341 1.2e-151 yqcI S YqcI/YcgG family
COHLBPCN_00342 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
COHLBPCN_00343 2.4e-112 ycgI S Domain of unknown function (DUF1989)
COHLBPCN_00344 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COHLBPCN_00345 2.5e-109 tmrB S AAA domain
COHLBPCN_00346 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COHLBPCN_00347 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
COHLBPCN_00348 2.2e-179 oxyR3 K LysR substrate binding domain
COHLBPCN_00349 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
COHLBPCN_00350 2.9e-145 ycgL S Predicted nucleotidyltransferase
COHLBPCN_00351 5.1e-170 ycgM E Proline dehydrogenase
COHLBPCN_00352 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
COHLBPCN_00353 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COHLBPCN_00354 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
COHLBPCN_00355 2.6e-147 ycgQ S membrane
COHLBPCN_00356 1.2e-139 ycgR S permeases
COHLBPCN_00357 5.7e-163 I alpha/beta hydrolase fold
COHLBPCN_00358 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
COHLBPCN_00359 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
COHLBPCN_00360 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
COHLBPCN_00361 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
COHLBPCN_00362 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COHLBPCN_00363 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
COHLBPCN_00364 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
COHLBPCN_00365 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
COHLBPCN_00366 5.5e-109 yciB M ErfK YbiS YcfS YnhG
COHLBPCN_00367 1.4e-228 yciC S GTPases (G3E family)
COHLBPCN_00368 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
COHLBPCN_00369 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
COHLBPCN_00372 3.3e-77 yckC S membrane
COHLBPCN_00373 3.5e-52 yckD S Protein of unknown function (DUF2680)
COHLBPCN_00374 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COHLBPCN_00375 3.4e-70 nin S Competence protein J (ComJ)
COHLBPCN_00376 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
COHLBPCN_00377 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
COHLBPCN_00378 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
COHLBPCN_00379 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
COHLBPCN_00380 1.3e-63 hxlR K transcriptional
COHLBPCN_00381 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_00382 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_00383 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
COHLBPCN_00384 5.7e-140 srfAD Q thioesterase
COHLBPCN_00385 4.2e-228 EGP Major Facilitator Superfamily
COHLBPCN_00386 4.9e-91 S YcxB-like protein
COHLBPCN_00387 7.4e-164 ycxC EG EamA-like transporter family
COHLBPCN_00388 4.4e-255 ycxD K GntR family transcriptional regulator
COHLBPCN_00389 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
COHLBPCN_00390 4.4e-115 yczE S membrane
COHLBPCN_00391 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
COHLBPCN_00392 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
COHLBPCN_00393 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
COHLBPCN_00394 4.9e-162 bsdA K LysR substrate binding domain
COHLBPCN_00395 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
COHLBPCN_00396 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
COHLBPCN_00397 4e-39 bsdD 4.1.1.61 S response to toxic substance
COHLBPCN_00398 1.1e-83 yclD
COHLBPCN_00399 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
COHLBPCN_00400 1.5e-267 dtpT E amino acid peptide transporter
COHLBPCN_00401 2.9e-310 yclG M Pectate lyase superfamily protein
COHLBPCN_00403 6.8e-282 gerKA EG Spore germination protein
COHLBPCN_00404 1.3e-232 gerKC S spore germination
COHLBPCN_00405 9.9e-200 gerKB F Spore germination protein
COHLBPCN_00406 3.9e-122 yclH P ABC transporter
COHLBPCN_00407 1.7e-204 yclI V ABC transporter (permease) YclI
COHLBPCN_00408 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_00409 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
COHLBPCN_00410 5.2e-71 S aspartate phosphatase
COHLBPCN_00413 7.5e-242 lysC 2.7.2.4 E Belongs to the aspartokinase family
COHLBPCN_00414 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_00415 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_00416 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
COHLBPCN_00417 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
COHLBPCN_00418 1.4e-251 ycnB EGP Major facilitator Superfamily
COHLBPCN_00419 6.5e-154 ycnC K Transcriptional regulator
COHLBPCN_00420 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
COHLBPCN_00421 1.6e-45 ycnE S Monooxygenase
COHLBPCN_00422 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
COHLBPCN_00423 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COHLBPCN_00424 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COHLBPCN_00425 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COHLBPCN_00426 6.1e-149 glcU U Glucose uptake
COHLBPCN_00427 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_00428 1.3e-100 ycnI S protein conserved in bacteria
COHLBPCN_00429 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
COHLBPCN_00430 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
COHLBPCN_00431 7.3e-56
COHLBPCN_00432 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
COHLBPCN_00433 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
COHLBPCN_00434 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
COHLBPCN_00435 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
COHLBPCN_00436 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
COHLBPCN_00437 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
COHLBPCN_00438 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
COHLBPCN_00439 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
COHLBPCN_00441 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
COHLBPCN_00442 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
COHLBPCN_00443 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
COHLBPCN_00444 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
COHLBPCN_00445 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
COHLBPCN_00446 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
COHLBPCN_00447 1.2e-132 kipR K Transcriptional regulator
COHLBPCN_00448 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
COHLBPCN_00450 1.4e-49 yczJ S biosynthesis
COHLBPCN_00451 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
COHLBPCN_00452 2.8e-176 ydhF S Oxidoreductase
COHLBPCN_00453 0.0 mtlR K transcriptional regulator, MtlR
COHLBPCN_00454 1.4e-294 ydaB IQ acyl-CoA ligase
COHLBPCN_00455 1.1e-99 ydaC Q Methyltransferase domain
COHLBPCN_00456 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_00457 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
COHLBPCN_00458 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
COHLBPCN_00459 6.8e-77 ydaG 1.4.3.5 S general stress protein
COHLBPCN_00460 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
COHLBPCN_00461 5.1e-47 ydzA EGP Major facilitator Superfamily
COHLBPCN_00462 2.5e-74 lrpC K Transcriptional regulator
COHLBPCN_00463 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COHLBPCN_00464 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
COHLBPCN_00465 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
COHLBPCN_00466 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
COHLBPCN_00467 4.5e-233 ydaM M Glycosyl transferase family group 2
COHLBPCN_00468 0.0 ydaN S Bacterial cellulose synthase subunit
COHLBPCN_00469 0.0 ydaO E amino acid
COHLBPCN_00470 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
COHLBPCN_00471 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COHLBPCN_00472 9.4e-40
COHLBPCN_00473 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
COHLBPCN_00475 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
COHLBPCN_00476 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
COHLBPCN_00478 8.9e-59 ydbB G Cupin domain
COHLBPCN_00479 2.8e-63 ydbC S Domain of unknown function (DUF4937
COHLBPCN_00480 3.2e-155 ydbD P Catalase
COHLBPCN_00481 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
COHLBPCN_00482 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
COHLBPCN_00483 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
COHLBPCN_00484 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COHLBPCN_00485 4.4e-181 ydbI S AI-2E family transporter
COHLBPCN_00486 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
COHLBPCN_00487 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
COHLBPCN_00488 2.7e-52 ydbL
COHLBPCN_00489 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
COHLBPCN_00490 1.1e-18 S Fur-regulated basic protein B
COHLBPCN_00491 2.2e-07 S Fur-regulated basic protein A
COHLBPCN_00492 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COHLBPCN_00493 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COHLBPCN_00494 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COHLBPCN_00495 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COHLBPCN_00496 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COHLBPCN_00497 2.1e-82 ydbS S Bacterial PH domain
COHLBPCN_00498 2.2e-263 ydbT S Membrane
COHLBPCN_00499 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
COHLBPCN_00500 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COHLBPCN_00501 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
COHLBPCN_00502 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COHLBPCN_00503 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
COHLBPCN_00504 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
COHLBPCN_00505 1.3e-143 rsbR T Positive regulator of sigma-B
COHLBPCN_00506 5.2e-57 rsbS T antagonist
COHLBPCN_00507 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
COHLBPCN_00508 7.1e-189 rsbU 3.1.3.3 KT phosphatase
COHLBPCN_00509 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
COHLBPCN_00510 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
COHLBPCN_00511 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COHLBPCN_00512 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
COHLBPCN_00516 1.5e-82 ydcG S EVE domain
COHLBPCN_00517 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_00518 0.0 yhgF K COG2183 Transcriptional accessory protein
COHLBPCN_00519 1.6e-84 ydcK S Belongs to the SprT family
COHLBPCN_00527 1.9e-211 L Belongs to the 'phage' integrase family
COHLBPCN_00528 1.3e-90 immA E IrrE N-terminal-like domain
COHLBPCN_00529 4.3e-62 yvaO K Transcriptional
COHLBPCN_00530 1.1e-16
COHLBPCN_00531 8.3e-41
COHLBPCN_00533 5.1e-63 S Bacterial protein of unknown function (DUF961)
COHLBPCN_00534 1e-273 ydcQ D Ftsk spoiiie family protein
COHLBPCN_00535 1.5e-205 nicK L Replication initiation factor
COHLBPCN_00538 1.2e-32 yddA
COHLBPCN_00539 1.5e-173 yddB S Conjugative transposon protein TcpC
COHLBPCN_00540 3e-40 yddC
COHLBPCN_00541 2.4e-95 yddD S TcpE family
COHLBPCN_00542 0.0 yddE S AAA-like domain
COHLBPCN_00543 2e-55 S Domain of unknown function (DUF1874)
COHLBPCN_00544 0.0 yddG S maturation of SSU-rRNA
COHLBPCN_00545 2.4e-189 yddH CBM50 M Lysozyme-like
COHLBPCN_00546 8.7e-87 yddI
COHLBPCN_00547 4.1e-65 S Domain of unknown function with cystatin-like fold (DUF4467)
COHLBPCN_00548 9.5e-128 S TIR domain
COHLBPCN_00549 1.4e-74 S response regulator aspartate phosphatase
COHLBPCN_00551 3.4e-161
COHLBPCN_00552 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COHLBPCN_00553 2.4e-71 lrpA K transcriptional
COHLBPCN_00554 3.9e-78 lrpB K transcriptional
COHLBPCN_00555 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
COHLBPCN_00556 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
COHLBPCN_00557 5e-227 ydeG EGP Major facilitator Superfamily
COHLBPCN_00562 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
COHLBPCN_00563 8.7e-30 cspL K Cold shock
COHLBPCN_00564 6.1e-79 carD K Transcription factor
COHLBPCN_00565 4.6e-35 ydzE EG spore germination
COHLBPCN_00566 1.1e-166 rhaS5 K AraC-like ligand binding domain
COHLBPCN_00567 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
COHLBPCN_00568 2.5e-166 ydeE K AraC family transcriptional regulator
COHLBPCN_00569 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COHLBPCN_00570 3.4e-220 ydeG EGP Major facilitator superfamily
COHLBPCN_00571 2.9e-47 ydeH
COHLBPCN_00572 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
COHLBPCN_00573 4e-116
COHLBPCN_00574 1.8e-153 ydeK EG -transporter
COHLBPCN_00575 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COHLBPCN_00576 4.2e-74 maoC I N-terminal half of MaoC dehydratase
COHLBPCN_00577 8.6e-107 ydeN S Serine hydrolase
COHLBPCN_00578 1.1e-58 K HxlR-like helix-turn-helix
COHLBPCN_00579 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
COHLBPCN_00580 4.8e-69 ydeP K Transcriptional regulator
COHLBPCN_00581 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
COHLBPCN_00582 1.2e-195 ydeR EGP Major facilitator Superfamily
COHLBPCN_00583 8.4e-105 ydeS K Transcriptional regulator
COHLBPCN_00584 1.3e-57 arsR K transcriptional
COHLBPCN_00585 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
COHLBPCN_00586 7.2e-149 ydfB J GNAT acetyltransferase
COHLBPCN_00587 1e-162 ydfC EG EamA-like transporter family
COHLBPCN_00588 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COHLBPCN_00589 5.9e-117 ydfE S Flavin reductase like domain
COHLBPCN_00590 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
COHLBPCN_00591 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COHLBPCN_00593 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
COHLBPCN_00594 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COHLBPCN_00595 0.0 ydfJ S drug exporters of the RND superfamily
COHLBPCN_00596 1.9e-177 S Alpha/beta hydrolase family
COHLBPCN_00597 5.9e-118 S Protein of unknown function (DUF554)
COHLBPCN_00598 3.2e-147 K Bacterial transcription activator, effector binding domain
COHLBPCN_00599 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COHLBPCN_00600 9.6e-112 ydfN C nitroreductase
COHLBPCN_00601 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
COHLBPCN_00602 8.8e-63 mhqP S DoxX
COHLBPCN_00603 1.3e-57 traF CO Thioredoxin
COHLBPCN_00604 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
COHLBPCN_00605 6.3e-29
COHLBPCN_00607 4.4e-118 ydfR S Protein of unknown function (DUF421)
COHLBPCN_00608 5.2e-122 ydfS S Protein of unknown function (DUF421)
COHLBPCN_00609 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
COHLBPCN_00610 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
COHLBPCN_00611 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
COHLBPCN_00612 1.5e-101 K Bacterial regulatory proteins, tetR family
COHLBPCN_00613 1.9e-53 S DoxX-like family
COHLBPCN_00614 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
COHLBPCN_00615 4.2e-308 expZ S ABC transporter
COHLBPCN_00616 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
COHLBPCN_00617 4.6e-91 dinB S DinB family
COHLBPCN_00618 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_00619 0.0 ydgH S drug exporters of the RND superfamily
COHLBPCN_00620 1e-113 drgA C nitroreductase
COHLBPCN_00621 1.1e-69 ydgJ K Winged helix DNA-binding domain
COHLBPCN_00622 2.5e-209 tcaB EGP Major facilitator Superfamily
COHLBPCN_00623 1.2e-121 ydhB S membrane transporter protein
COHLBPCN_00624 6.5e-122 ydhC K FCD
COHLBPCN_00625 3.3e-244 ydhD M Glycosyl hydrolase
COHLBPCN_00626 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
COHLBPCN_00627 1.9e-127
COHLBPCN_00628 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
COHLBPCN_00629 4.6e-69 frataxin S Domain of unknown function (DU1801)
COHLBPCN_00631 4.1e-86 K Acetyltransferase (GNAT) domain
COHLBPCN_00632 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COHLBPCN_00633 1.7e-99 ydhK M Protein of unknown function (DUF1541)
COHLBPCN_00634 4.6e-200 pbuE EGP Major facilitator Superfamily
COHLBPCN_00635 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
COHLBPCN_00636 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
COHLBPCN_00637 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COHLBPCN_00638 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COHLBPCN_00639 3.9e-133 ydhQ K UTRA
COHLBPCN_00640 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
COHLBPCN_00641 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
COHLBPCN_00642 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
COHLBPCN_00643 8.7e-78 ydhU P Catalase
COHLBPCN_00644 1.1e-16 ydhU P Manganese containing catalase
COHLBPCN_00647 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00648 7.8e-08
COHLBPCN_00650 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
COHLBPCN_00651 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
COHLBPCN_00652 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
COHLBPCN_00653 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
COHLBPCN_00654 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COHLBPCN_00655 0.0 ydiF S ABC transporter
COHLBPCN_00656 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
COHLBPCN_00657 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COHLBPCN_00658 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
COHLBPCN_00659 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COHLBPCN_00660 2.9e-27 ydiK S Domain of unknown function (DUF4305)
COHLBPCN_00661 7.9e-129 ydiL S CAAX protease self-immunity
COHLBPCN_00662 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COHLBPCN_00663 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COHLBPCN_00665 6.4e-66 KL Phage plasmid primase P4 family
COHLBPCN_00666 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
COHLBPCN_00667 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
COHLBPCN_00669 1.2e-199 V AAA domain (dynein-related subfamily)
COHLBPCN_00670 4.9e-257 J LlaJI restriction endonuclease
COHLBPCN_00671 1.1e-08 ydjC S Abhydrolase domain containing 18
COHLBPCN_00672 0.0 K NB-ARC domain
COHLBPCN_00673 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
COHLBPCN_00674 7.1e-256 gutA G MFS/sugar transport protein
COHLBPCN_00675 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
COHLBPCN_00676 5.1e-114 pspA KT Phage shock protein A
COHLBPCN_00677 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COHLBPCN_00678 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
COHLBPCN_00679 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
COHLBPCN_00680 4.7e-196 S Ion transport 2 domain protein
COHLBPCN_00681 2.7e-258 iolT EGP Major facilitator Superfamily
COHLBPCN_00682 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
COHLBPCN_00683 4.5e-64 ydjM M Lytic transglycolase
COHLBPCN_00684 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
COHLBPCN_00686 1.4e-34 ydjO S Cold-inducible protein YdjO
COHLBPCN_00687 9.5e-160 ydjP I Alpha/beta hydrolase family
COHLBPCN_00688 2.4e-181 yeaA S Protein of unknown function (DUF4003)
COHLBPCN_00689 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
COHLBPCN_00690 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
COHLBPCN_00691 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COHLBPCN_00692 1.6e-177 yeaC S COG0714 MoxR-like ATPases
COHLBPCN_00693 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
COHLBPCN_00694 0.0 yebA E COG1305 Transglutaminase-like enzymes
COHLBPCN_00695 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COHLBPCN_00696 6e-212 pbuG S permease
COHLBPCN_00697 1.1e-118 yebC M Membrane
COHLBPCN_00699 4e-93 yebE S UPF0316 protein
COHLBPCN_00700 8e-28 yebG S NETI protein
COHLBPCN_00701 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COHLBPCN_00702 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COHLBPCN_00703 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COHLBPCN_00704 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
COHLBPCN_00705 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COHLBPCN_00706 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COHLBPCN_00707 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COHLBPCN_00708 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COHLBPCN_00709 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COHLBPCN_00710 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COHLBPCN_00711 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COHLBPCN_00712 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
COHLBPCN_00713 3.5e-73 K helix_turn_helix ASNC type
COHLBPCN_00714 2.3e-232 yjeH E Amino acid permease
COHLBPCN_00715 2.7e-27 S Protein of unknown function (DUF2892)
COHLBPCN_00716 0.0 yerA 3.5.4.2 F adenine deaminase
COHLBPCN_00717 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
COHLBPCN_00718 4.8e-51 yerC S protein conserved in bacteria
COHLBPCN_00719 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
COHLBPCN_00721 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
COHLBPCN_00722 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COHLBPCN_00723 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COHLBPCN_00724 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
COHLBPCN_00725 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
COHLBPCN_00726 1.6e-123 sapB S MgtC SapB transporter
COHLBPCN_00727 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COHLBPCN_00728 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COHLBPCN_00729 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COHLBPCN_00730 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COHLBPCN_00731 4e-156 yerO K Transcriptional regulator
COHLBPCN_00732 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COHLBPCN_00733 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
COHLBPCN_00734 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COHLBPCN_00735 3.2e-98 L Recombinase
COHLBPCN_00736 3.2e-53 L Resolvase, N terminal domain
COHLBPCN_00737 0.0 yeeA V Type II restriction enzyme, methylase subunits
COHLBPCN_00738 0.0 yeeB L DEAD-like helicases superfamily
COHLBPCN_00739 1.8e-212 pstS P T5orf172
COHLBPCN_00741 6.2e-31 S Colicin immunity protein / pyocin immunity protein
COHLBPCN_00742 5.5e-83 S Protein of unknown function, DUF600
COHLBPCN_00743 0.0 L nucleic acid phosphodiester bond hydrolysis
COHLBPCN_00744 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
COHLBPCN_00745 5.5e-214 S Tetratricopeptide repeat
COHLBPCN_00747 9.4e-127 yeeN K transcriptional regulatory protein
COHLBPCN_00749 1.2e-103 dhaR3 K Transcriptional regulator
COHLBPCN_00750 9.7e-82 yesE S SnoaL-like domain
COHLBPCN_00751 2.2e-159 yesF GM NAD(P)H-binding
COHLBPCN_00752 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
COHLBPCN_00753 1.5e-45 cotJB S CotJB protein
COHLBPCN_00754 5.2e-104 cotJC P Spore Coat
COHLBPCN_00755 4.2e-103 yesJ K Acetyltransferase (GNAT) family
COHLBPCN_00757 4.4e-104 yesL S Protein of unknown function, DUF624
COHLBPCN_00758 0.0 yesM 2.7.13.3 T Histidine kinase
COHLBPCN_00759 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
COHLBPCN_00760 5e-248 yesO G Bacterial extracellular solute-binding protein
COHLBPCN_00761 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
COHLBPCN_00762 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
COHLBPCN_00763 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
COHLBPCN_00764 0.0 yesS K Transcriptional regulator
COHLBPCN_00765 3.8e-133 E GDSL-like Lipase/Acylhydrolase
COHLBPCN_00766 8.9e-132 yesU S Domain of unknown function (DUF1961)
COHLBPCN_00767 1e-113 yesV S Protein of unknown function, DUF624
COHLBPCN_00768 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
COHLBPCN_00769 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
COHLBPCN_00770 3e-124 yesY E GDSL-like Lipase/Acylhydrolase
COHLBPCN_00771 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
COHLBPCN_00772 0.0 yetA
COHLBPCN_00773 9.6e-291 lplA G Bacterial extracellular solute-binding protein
COHLBPCN_00774 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
COHLBPCN_00775 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
COHLBPCN_00776 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
COHLBPCN_00777 6.1e-123 yetF S membrane
COHLBPCN_00778 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
COHLBPCN_00779 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COHLBPCN_00780 2.2e-34
COHLBPCN_00781 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COHLBPCN_00782 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COHLBPCN_00783 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
COHLBPCN_00784 5.3e-105 yetJ S Belongs to the BI1 family
COHLBPCN_00785 5.4e-159 yetK EG EamA-like transporter family
COHLBPCN_00786 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_00787 7.8e-213 yetM CH FAD binding domain
COHLBPCN_00788 3.6e-199 yetN S Protein of unknown function (DUF3900)
COHLBPCN_00789 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
COHLBPCN_00790 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
COHLBPCN_00791 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
COHLBPCN_00792 1.9e-172 yfnG 4.2.1.45 M dehydratase
COHLBPCN_00793 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
COHLBPCN_00794 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
COHLBPCN_00795 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
COHLBPCN_00796 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
COHLBPCN_00797 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COHLBPCN_00798 1.3e-241 yfnA E amino acid
COHLBPCN_00799 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COHLBPCN_00800 1.1e-113 yfmS NT chemotaxis protein
COHLBPCN_00801 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
COHLBPCN_00802 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
COHLBPCN_00803 2.8e-70 yfmP K transcriptional
COHLBPCN_00804 1.5e-209 yfmO EGP Major facilitator Superfamily
COHLBPCN_00805 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
COHLBPCN_00806 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
COHLBPCN_00807 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
COHLBPCN_00808 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
COHLBPCN_00809 7.7e-214 G Major Facilitator Superfamily
COHLBPCN_00810 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
COHLBPCN_00811 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
COHLBPCN_00812 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_00813 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_00814 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
COHLBPCN_00815 2.9e-24 S Protein of unknown function (DUF3212)
COHLBPCN_00816 7.6e-58 yflT S Heat induced stress protein YflT
COHLBPCN_00817 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
COHLBPCN_00818 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
COHLBPCN_00819 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
COHLBPCN_00820 8.9e-119 citT T response regulator
COHLBPCN_00821 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
COHLBPCN_00823 8.5e-227 citM C Citrate transporter
COHLBPCN_00824 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
COHLBPCN_00825 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
COHLBPCN_00826 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COHLBPCN_00827 9e-124 yflK S protein conserved in bacteria
COHLBPCN_00828 4e-18 yflJ S Protein of unknown function (DUF2639)
COHLBPCN_00829 4.1e-19 yflI
COHLBPCN_00830 2.4e-50 yflH S Protein of unknown function (DUF3243)
COHLBPCN_00831 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
COHLBPCN_00832 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
COHLBPCN_00833 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
COHLBPCN_00834 6e-67 yhdN S Domain of unknown function (DUF1992)
COHLBPCN_00835 3.2e-256 agcS_1 E Sodium alanine symporter
COHLBPCN_00836 1.6e-194 E Spore germination protein
COHLBPCN_00838 5.1e-207 yfkR S spore germination
COHLBPCN_00839 1.5e-283 yfkQ EG Spore germination protein
COHLBPCN_00840 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COHLBPCN_00841 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
COHLBPCN_00842 1.8e-133 treR K transcriptional
COHLBPCN_00843 1.6e-125 yfkO C nitroreductase
COHLBPCN_00844 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
COHLBPCN_00845 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
COHLBPCN_00846 6.8e-207 ydiM EGP Major facilitator Superfamily
COHLBPCN_00847 2.1e-29 yfkK S Belongs to the UPF0435 family
COHLBPCN_00848 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COHLBPCN_00849 8.4e-51 yfkI S gas vesicle protein
COHLBPCN_00850 9.7e-144 yihY S Belongs to the UPF0761 family
COHLBPCN_00851 5e-08
COHLBPCN_00852 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
COHLBPCN_00853 6.1e-183 cax P COG0387 Ca2 H antiporter
COHLBPCN_00854 1.2e-146 yfkD S YfkD-like protein
COHLBPCN_00855 6e-149 yfkC M Mechanosensitive ion channel
COHLBPCN_00856 5.4e-222 yfkA S YfkB-like domain
COHLBPCN_00857 1.1e-26 yfjT
COHLBPCN_00858 2.6e-154 pdaA G deacetylase
COHLBPCN_00859 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
COHLBPCN_00860 1.7e-184 corA P Mediates influx of magnesium ions
COHLBPCN_00861 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
COHLBPCN_00862 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COHLBPCN_00863 1.6e-39 S YfzA-like protein
COHLBPCN_00864 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COHLBPCN_00865 3.9e-86 yfjM S Psort location Cytoplasmic, score
COHLBPCN_00866 3e-29 yfjL
COHLBPCN_00867 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
COHLBPCN_00868 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
COHLBPCN_00869 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COHLBPCN_00870 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
COHLBPCN_00871 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
COHLBPCN_00872 1.2e-25 sspH S Belongs to the SspH family
COHLBPCN_00873 4e-56 yfjF S UPF0060 membrane protein
COHLBPCN_00874 1.3e-80 S Family of unknown function (DUF5381)
COHLBPCN_00875 1.8e-101 yfjD S Family of unknown function (DUF5381)
COHLBPCN_00876 4.1e-144 yfjC
COHLBPCN_00877 9.2e-191 yfjB
COHLBPCN_00878 1.1e-44 yfjA S Belongs to the WXG100 family
COHLBPCN_00879 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
COHLBPCN_00880 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
COHLBPCN_00881 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COHLBPCN_00882 2.1e-310 yfiB3 V ABC transporter
COHLBPCN_00883 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
COHLBPCN_00884 9.8e-65 mhqP S DoxX
COHLBPCN_00885 5.7e-163 yfiE 1.13.11.2 S glyoxalase
COHLBPCN_00886 1.5e-177 K AraC-like ligand binding domain
COHLBPCN_00887 1.8e-262 iolT EGP Major facilitator Superfamily
COHLBPCN_00888 8.4e-184 G Xylose isomerase
COHLBPCN_00889 1.1e-233 S Oxidoreductase
COHLBPCN_00891 1.1e-214 yxjM T Histidine kinase
COHLBPCN_00892 3.2e-113 KT LuxR family transcriptional regulator
COHLBPCN_00893 6.2e-171 V ABC transporter, ATP-binding protein
COHLBPCN_00894 9.8e-214 V ABC-2 family transporter protein
COHLBPCN_00895 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
COHLBPCN_00896 8.3e-99 padR K transcriptional
COHLBPCN_00897 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
COHLBPCN_00898 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
COHLBPCN_00899 2e-109 yfiR K Transcriptional regulator
COHLBPCN_00900 5.1e-221 yfiS EGP Major facilitator Superfamily
COHLBPCN_00901 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
COHLBPCN_00902 8.7e-287 yfiU EGP Major facilitator Superfamily
COHLBPCN_00903 3.1e-81 yfiV K transcriptional
COHLBPCN_00904 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COHLBPCN_00905 6.2e-182 yfiY P ABC transporter substrate-binding protein
COHLBPCN_00906 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_00907 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_00908 1.8e-167 yfhB 5.3.3.17 S PhzF family
COHLBPCN_00909 3.9e-107 yfhC C nitroreductase
COHLBPCN_00910 2.1e-25 yfhD S YfhD-like protein
COHLBPCN_00912 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
COHLBPCN_00913 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
COHLBPCN_00914 9.7e-52 yfhH S Protein of unknown function (DUF1811)
COHLBPCN_00916 1.1e-209 yfhI EGP Major facilitator Superfamily
COHLBPCN_00917 6.2e-20 sspK S reproduction
COHLBPCN_00918 1.3e-44 yfhJ S WVELL protein
COHLBPCN_00919 9.2e-92 batE T Bacterial SH3 domain homologues
COHLBPCN_00920 3.5e-51 yfhL S SdpI/YhfL protein family
COHLBPCN_00921 6.7e-172 yfhM S Alpha beta hydrolase
COHLBPCN_00922 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COHLBPCN_00923 0.0 yfhO S Bacterial membrane protein YfhO
COHLBPCN_00924 5.5e-186 yfhP S membrane-bound metal-dependent
COHLBPCN_00925 7.8e-212 mutY L A G-specific
COHLBPCN_00926 6.9e-36 yfhS
COHLBPCN_00927 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_00928 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
COHLBPCN_00929 1.5e-37 ygaB S YgaB-like protein
COHLBPCN_00930 1.3e-104 ygaC J Belongs to the UPF0374 family
COHLBPCN_00931 1.8e-301 ygaD V ABC transporter
COHLBPCN_00932 8.7e-180 ygaE S Membrane
COHLBPCN_00933 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
COHLBPCN_00934 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
COHLBPCN_00935 4e-80 perR P Belongs to the Fur family
COHLBPCN_00936 1.5e-56 ygzB S UPF0295 protein
COHLBPCN_00937 6.7e-167 ygxA S Nucleotidyltransferase-like
COHLBPCN_00938 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_00943 7.8e-08
COHLBPCN_00951 2e-08
COHLBPCN_00955 2.7e-143 spo0M S COG4326 Sporulation control protein
COHLBPCN_00956 3e-27
COHLBPCN_00957 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
COHLBPCN_00958 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
COHLBPCN_00959 1.9e-266 ygaK C Berberine and berberine like
COHLBPCN_00961 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
COHLBPCN_00962 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
COHLBPCN_00963 1.7e-171 ssuA M Sulfonate ABC transporter
COHLBPCN_00964 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
COHLBPCN_00965 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
COHLBPCN_00967 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COHLBPCN_00968 4.1e-78 ygaO
COHLBPCN_00969 4.4e-29 K Transcriptional regulator
COHLBPCN_00971 7.9e-114 yhzB S B3/4 domain
COHLBPCN_00972 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
COHLBPCN_00973 4.4e-177 yhbB S Putative amidase domain
COHLBPCN_00974 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COHLBPCN_00975 1.2e-109 yhbD K Protein of unknown function (DUF4004)
COHLBPCN_00976 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
COHLBPCN_00977 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
COHLBPCN_00978 0.0 prkA T Ser protein kinase
COHLBPCN_00979 2.5e-225 yhbH S Belongs to the UPF0229 family
COHLBPCN_00980 2.2e-76 yhbI K DNA-binding transcription factor activity
COHLBPCN_00981 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
COHLBPCN_00982 3.1e-271 yhcA EGP Major facilitator Superfamily
COHLBPCN_00983 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
COHLBPCN_00984 2.8e-37 yhcC
COHLBPCN_00985 7.8e-55
COHLBPCN_00986 6.6e-60 yhcF K Transcriptional regulator
COHLBPCN_00987 1.6e-123 yhcG V ABC transporter, ATP-binding protein
COHLBPCN_00988 2.6e-166 yhcH V ABC transporter, ATP-binding protein
COHLBPCN_00989 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
COHLBPCN_00990 1e-30 cspB K Cold-shock protein
COHLBPCN_00991 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
COHLBPCN_00992 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
COHLBPCN_00993 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COHLBPCN_00994 3.7e-44 yhcM
COHLBPCN_00995 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
COHLBPCN_00996 2.5e-167 yhcP
COHLBPCN_00997 5.2e-100 yhcQ M Spore coat protein
COHLBPCN_00998 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
COHLBPCN_00999 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
COHLBPCN_01000 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COHLBPCN_01001 9.3e-68 yhcU S Family of unknown function (DUF5365)
COHLBPCN_01002 9.9e-68 yhcV S COG0517 FOG CBS domain
COHLBPCN_01003 4.6e-120 yhcW 5.4.2.6 S hydrolase
COHLBPCN_01004 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
COHLBPCN_01005 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COHLBPCN_01006 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
COHLBPCN_01007 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
COHLBPCN_01008 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COHLBPCN_01009 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
COHLBPCN_01010 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
COHLBPCN_01011 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
COHLBPCN_01012 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COHLBPCN_01013 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
COHLBPCN_01014 1.2e-38 yhdB S YhdB-like protein
COHLBPCN_01015 4.8e-54 yhdC S Protein of unknown function (DUF3889)
COHLBPCN_01016 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
COHLBPCN_01017 3.5e-76 nsrR K Transcriptional regulator
COHLBPCN_01018 8.7e-239 ygxB M Conserved TM helix
COHLBPCN_01019 2.1e-276 ycgB S Stage V sporulation protein R
COHLBPCN_01020 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
COHLBPCN_01021 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
COHLBPCN_01022 3.8e-162 citR K Transcriptional regulator
COHLBPCN_01023 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
COHLBPCN_01024 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_01025 3.4e-250 yhdG E amino acid
COHLBPCN_01026 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
COHLBPCN_01027 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COHLBPCN_01028 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COHLBPCN_01029 8.1e-45 yhdK S Sigma-M inhibitor protein
COHLBPCN_01030 6.6e-201 yhdL S Sigma factor regulator N-terminal
COHLBPCN_01031 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_01032 1.5e-191 yhdN C Aldo keto reductase
COHLBPCN_01033 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
COHLBPCN_01034 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
COHLBPCN_01035 4.1e-74 cueR K transcriptional
COHLBPCN_01036 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
COHLBPCN_01037 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
COHLBPCN_01038 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COHLBPCN_01039 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COHLBPCN_01040 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COHLBPCN_01042 6.6e-204 yhdY M Mechanosensitive ion channel
COHLBPCN_01043 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
COHLBPCN_01044 1.7e-151 yheN G deacetylase
COHLBPCN_01045 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
COHLBPCN_01046 2.2e-233 nhaC C Na H antiporter
COHLBPCN_01047 3.4e-84 nhaX T Belongs to the universal stress protein A family
COHLBPCN_01048 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
COHLBPCN_01049 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
COHLBPCN_01050 3.7e-111 yheG GM NAD(P)H-binding
COHLBPCN_01051 6.3e-28 sspB S spore protein
COHLBPCN_01052 1.3e-36 yheE S Family of unknown function (DUF5342)
COHLBPCN_01053 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
COHLBPCN_01054 4.3e-216 yheC HJ YheC/D like ATP-grasp
COHLBPCN_01055 6.7e-204 yheB S Belongs to the UPF0754 family
COHLBPCN_01056 9.5e-48 yheA S Belongs to the UPF0342 family
COHLBPCN_01057 3.1e-206 yhaZ L DNA alkylation repair enzyme
COHLBPCN_01058 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
COHLBPCN_01059 7.1e-294 hemZ H coproporphyrinogen III oxidase
COHLBPCN_01060 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
COHLBPCN_01061 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
COHLBPCN_01063 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
COHLBPCN_01064 1.1e-26 S YhzD-like protein
COHLBPCN_01065 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
COHLBPCN_01066 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
COHLBPCN_01067 3.6e-227 yhaO L DNA repair exonuclease
COHLBPCN_01068 0.0 yhaN L AAA domain
COHLBPCN_01069 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
COHLBPCN_01070 1.6e-21 yhaL S Sporulation protein YhaL
COHLBPCN_01071 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COHLBPCN_01072 8.7e-90 yhaK S Putative zincin peptidase
COHLBPCN_01073 1.3e-54 yhaI S Protein of unknown function (DUF1878)
COHLBPCN_01074 1e-113 hpr K Negative regulator of protease production and sporulation
COHLBPCN_01075 7e-39 yhaH S YtxH-like protein
COHLBPCN_01076 3.6e-80 trpP S Tryptophan transporter TrpP
COHLBPCN_01077 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COHLBPCN_01078 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
COHLBPCN_01079 4.6e-137 ecsA V transporter (ATP-binding protein)
COHLBPCN_01080 1.8e-215 ecsB U ABC transporter
COHLBPCN_01081 4.8e-115 ecsC S EcsC protein family
COHLBPCN_01082 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
COHLBPCN_01083 4.2e-248 yhfA C membrane
COHLBPCN_01084 7.5e-17 1.15.1.2 C Rubrerythrin
COHLBPCN_01085 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
COHLBPCN_01086 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COHLBPCN_01087 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
COHLBPCN_01088 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
COHLBPCN_01089 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
COHLBPCN_01090 1.4e-101 yhgD K Transcriptional regulator
COHLBPCN_01091 1e-238 yhgE S YhgE Pip N-terminal domain protein
COHLBPCN_01092 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COHLBPCN_01093 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
COHLBPCN_01094 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
COHLBPCN_01095 1.7e-72 3.4.13.21 S ASCH
COHLBPCN_01096 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COHLBPCN_01097 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
COHLBPCN_01098 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
COHLBPCN_01099 2.6e-112 yhfK GM NmrA-like family
COHLBPCN_01100 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
COHLBPCN_01101 1.9e-65 yhfM
COHLBPCN_01102 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
COHLBPCN_01103 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
COHLBPCN_01104 9.2e-80 VY92_01935 K acetyltransferase
COHLBPCN_01105 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
COHLBPCN_01106 4.3e-159 yfmC M Periplasmic binding protein
COHLBPCN_01107 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
COHLBPCN_01108 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
COHLBPCN_01109 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
COHLBPCN_01110 5e-91 bioY S BioY family
COHLBPCN_01111 1.7e-182 hemAT NT chemotaxis protein
COHLBPCN_01112 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
COHLBPCN_01113 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_01114 1.3e-32 yhzC S IDEAL
COHLBPCN_01115 4.2e-109 comK K Competence transcription factor
COHLBPCN_01116 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
COHLBPCN_01117 7.8e-42 yhjA S Excalibur calcium-binding domain
COHLBPCN_01118 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COHLBPCN_01119 6.9e-27 yhjC S Protein of unknown function (DUF3311)
COHLBPCN_01120 5e-60 yhjD
COHLBPCN_01121 9.1e-110 yhjE S SNARE associated Golgi protein
COHLBPCN_01122 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
COHLBPCN_01123 1.1e-286 yhjG CH FAD binding domain
COHLBPCN_01124 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_01125 6.9e-215 glcP G Major Facilitator Superfamily
COHLBPCN_01126 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
COHLBPCN_01127 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
COHLBPCN_01128 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
COHLBPCN_01129 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
COHLBPCN_01130 3.8e-202 abrB S membrane
COHLBPCN_01131 3.1e-215 EGP Transmembrane secretion effector
COHLBPCN_01132 0.0 S Sugar transport-related sRNA regulator N-term
COHLBPCN_01133 2e-36 yhjQ C COG1145 Ferredoxin
COHLBPCN_01134 2.2e-78 yhjR S Rubrerythrin
COHLBPCN_01135 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
COHLBPCN_01136 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COHLBPCN_01137 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COHLBPCN_01138 0.0 sbcC L COG0419 ATPase involved in DNA repair
COHLBPCN_01139 6e-51 yisB V COG1403 Restriction endonuclease
COHLBPCN_01140 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
COHLBPCN_01141 3e-66 gerPE S Spore germination protein GerPE
COHLBPCN_01142 6.3e-24 gerPD S Spore germination protein
COHLBPCN_01143 1.8e-54 gerPC S Spore germination protein
COHLBPCN_01144 4e-34 gerPB S cell differentiation
COHLBPCN_01145 1.9e-33 gerPA S Spore germination protein
COHLBPCN_01146 1.5e-22 yisI S Spo0E like sporulation regulatory protein
COHLBPCN_01147 1.7e-176 cotH M Spore Coat
COHLBPCN_01148 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
COHLBPCN_01149 3e-57 yisL S UPF0344 protein
COHLBPCN_01150 0.0 wprA O Belongs to the peptidase S8 family
COHLBPCN_01151 6.1e-105 yisN S Protein of unknown function (DUF2777)
COHLBPCN_01152 0.0 asnO 6.3.5.4 E Asparagine synthase
COHLBPCN_01153 2.1e-88 yizA S Damage-inducible protein DinB
COHLBPCN_01154 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
COHLBPCN_01155 4e-243 yisQ V Mate efflux family protein
COHLBPCN_01156 1.2e-160 yisR K Transcriptional regulator
COHLBPCN_01157 2.4e-184 purR K helix_turn _helix lactose operon repressor
COHLBPCN_01158 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
COHLBPCN_01159 1.3e-93 yisT S DinB family
COHLBPCN_01160 6.4e-108 argO S Lysine exporter protein LysE YggA
COHLBPCN_01161 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COHLBPCN_01162 4e-36 mcbG S Pentapeptide repeats (9 copies)
COHLBPCN_01163 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COHLBPCN_01164 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
COHLBPCN_01165 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
COHLBPCN_01166 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
COHLBPCN_01167 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
COHLBPCN_01168 1.9e-141 yitD 4.4.1.19 S synthase
COHLBPCN_01169 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COHLBPCN_01170 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
COHLBPCN_01171 4e-229 yitG EGP Major facilitator Superfamily
COHLBPCN_01172 1.8e-161 yitH K Acetyltransferase (GNAT) domain
COHLBPCN_01173 2e-82 yjcF S Acetyltransferase (GNAT) domain
COHLBPCN_01174 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
COHLBPCN_01175 8.6e-55 yajQ S Belongs to the UPF0234 family
COHLBPCN_01176 4e-161 cvfB S protein conserved in bacteria
COHLBPCN_01177 8.5e-94
COHLBPCN_01178 2.8e-171
COHLBPCN_01179 1.5e-97 S Sporulation delaying protein SdpA
COHLBPCN_01180 1.5e-58 K Transcriptional regulator PadR-like family
COHLBPCN_01181 2e-95
COHLBPCN_01182 1.4e-44 yitR S Domain of unknown function (DUF3784)
COHLBPCN_01183 2.2e-311 nprB 3.4.24.28 E Peptidase M4
COHLBPCN_01184 8.4e-159 yitS S protein conserved in bacteria
COHLBPCN_01185 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
COHLBPCN_01186 1.9e-72 ipi S Intracellular proteinase inhibitor
COHLBPCN_01187 1.2e-17 S Protein of unknown function (DUF3813)
COHLBPCN_01188 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
COHLBPCN_01189 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
COHLBPCN_01190 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
COHLBPCN_01191 1.5e-22 pilT S Proteolipid membrane potential modulator
COHLBPCN_01192 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
COHLBPCN_01193 1.7e-88 norB G Major Facilitator Superfamily
COHLBPCN_01194 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
COHLBPCN_01195 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
COHLBPCN_01196 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
COHLBPCN_01197 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
COHLBPCN_01198 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COHLBPCN_01199 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
COHLBPCN_01200 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COHLBPCN_01201 9.5e-28 yjzC S YjzC-like protein
COHLBPCN_01202 2.3e-16 yjzD S Protein of unknown function (DUF2929)
COHLBPCN_01203 6.2e-142 yjaU I carboxylic ester hydrolase activity
COHLBPCN_01204 7.3e-103 yjaV
COHLBPCN_01205 1.1e-183 med S Transcriptional activator protein med
COHLBPCN_01206 7.3e-26 comZ S ComZ
COHLBPCN_01207 2.7e-22 yjzB
COHLBPCN_01208 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COHLBPCN_01209 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COHLBPCN_01210 7.8e-151 yjaZ O Zn-dependent protease
COHLBPCN_01211 1.8e-184 appD P Belongs to the ABC transporter superfamily
COHLBPCN_01212 6.5e-187 appF E Belongs to the ABC transporter superfamily
COHLBPCN_01213 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
COHLBPCN_01214 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COHLBPCN_01215 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COHLBPCN_01216 5e-147 yjbA S Belongs to the UPF0736 family
COHLBPCN_01217 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
COHLBPCN_01218 0.0 oppA E ABC transporter substrate-binding protein
COHLBPCN_01219 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COHLBPCN_01220 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COHLBPCN_01221 3e-198 oppD P Belongs to the ABC transporter superfamily
COHLBPCN_01222 5.5e-172 oppF E Belongs to the ABC transporter superfamily
COHLBPCN_01223 8.6e-196 yjbB EGP Major Facilitator Superfamily
COHLBPCN_01224 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COHLBPCN_01225 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COHLBPCN_01226 6e-112 yjbE P Integral membrane protein TerC family
COHLBPCN_01227 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
COHLBPCN_01228 2.3e-223 yjbF S Competence protein
COHLBPCN_01229 0.0 pepF E oligoendopeptidase F
COHLBPCN_01230 1.8e-20
COHLBPCN_01232 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
COHLBPCN_01233 3.7e-72 yjbI S Bacterial-like globin
COHLBPCN_01234 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
COHLBPCN_01235 2.4e-101 yjbK S protein conserved in bacteria
COHLBPCN_01236 7.1e-62 yjbL S Belongs to the UPF0738 family
COHLBPCN_01237 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
COHLBPCN_01238 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COHLBPCN_01239 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COHLBPCN_01240 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
COHLBPCN_01241 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COHLBPCN_01242 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
COHLBPCN_01243 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
COHLBPCN_01244 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
COHLBPCN_01245 3e-30 thiS H thiamine diphosphate biosynthetic process
COHLBPCN_01246 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
COHLBPCN_01247 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
COHLBPCN_01248 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COHLBPCN_01249 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
COHLBPCN_01250 5.9e-54 yjbX S Spore coat protein
COHLBPCN_01251 5.2e-83 cotZ S Spore coat protein
COHLBPCN_01252 3.4e-96 cotY S Spore coat protein Z
COHLBPCN_01253 6.4e-77 cotX S Spore Coat Protein X and V domain
COHLBPCN_01254 3e-32 cotW
COHLBPCN_01255 2.3e-55 cotV S Spore Coat Protein X and V domain
COHLBPCN_01256 8.7e-57 yjcA S Protein of unknown function (DUF1360)
COHLBPCN_01259 2.9e-38 spoVIF S Stage VI sporulation protein F
COHLBPCN_01260 0.0 yjcD 3.6.4.12 L DNA helicase
COHLBPCN_01261 1.7e-38
COHLBPCN_01262 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COHLBPCN_01263 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
COHLBPCN_01264 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
COHLBPCN_01265 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COHLBPCN_01266 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COHLBPCN_01267 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
COHLBPCN_01268 1.1e-212 yjcL S Protein of unknown function (DUF819)
COHLBPCN_01271 2.1e-190 S Putative amidase domain
COHLBPCN_01272 2.6e-44 yjcN
COHLBPCN_01275 8.5e-81 L Transposase
COHLBPCN_01276 1.6e-72 yjcP
COHLBPCN_01277 4.1e-49 S YjcQ protein
COHLBPCN_01278 1.1e-92 yqaS L DNA packaging
COHLBPCN_01279 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
COHLBPCN_01280 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
COHLBPCN_01282 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
COHLBPCN_01283 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
COHLBPCN_01284 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
COHLBPCN_01285 4.8e-51 yjdF S Protein of unknown function (DUF2992)
COHLBPCN_01286 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
COHLBPCN_01288 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COHLBPCN_01289 4.2e-29 S Domain of unknown function (DUF4177)
COHLBPCN_01290 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
COHLBPCN_01291 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
COHLBPCN_01293 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
COHLBPCN_01294 5.5e-83 S Protein of unknown function (DUF2690)
COHLBPCN_01295 3.6e-21 yjfB S Putative motility protein
COHLBPCN_01296 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
COHLBPCN_01297 1.2e-45 T PhoQ Sensor
COHLBPCN_01298 8.9e-104 yjgB S Domain of unknown function (DUF4309)
COHLBPCN_01299 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
COHLBPCN_01300 4.3e-95 yjgD S Protein of unknown function (DUF1641)
COHLBPCN_01301 8.7e-07 S Domain of unknown function (DUF4352)
COHLBPCN_01302 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
COHLBPCN_01304 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
COHLBPCN_01305 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
COHLBPCN_01306 8.2e-30
COHLBPCN_01307 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
COHLBPCN_01308 1.9e-122 ybbM S transport system, permease component
COHLBPCN_01309 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
COHLBPCN_01310 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
COHLBPCN_01311 2.8e-93 yjlB S Cupin domain
COHLBPCN_01312 7.1e-66 yjlC S Protein of unknown function (DUF1641)
COHLBPCN_01313 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
COHLBPCN_01314 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
COHLBPCN_01315 5.8e-250 yjmB G symporter YjmB
COHLBPCN_01316 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
COHLBPCN_01317 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
COHLBPCN_01318 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
COHLBPCN_01319 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_01320 3.7e-227 exuT G Sugar (and other) transporter
COHLBPCN_01321 2.3e-184 exuR K transcriptional
COHLBPCN_01322 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
COHLBPCN_01323 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
COHLBPCN_01324 4.3e-130 MA20_18170 S membrane transporter protein
COHLBPCN_01325 3.3e-80 yjoA S DinB family
COHLBPCN_01326 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
COHLBPCN_01327 2.1e-213 S response regulator aspartate phosphatase
COHLBPCN_01329 6.3e-41 S YCII-related domain
COHLBPCN_01330 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
COHLBPCN_01331 2.1e-61 yjqA S Bacterial PH domain
COHLBPCN_01332 4.2e-112 yjqB S Pfam:DUF867
COHLBPCN_01333 4.4e-160 ydbD P Catalase
COHLBPCN_01334 1.6e-111 xkdA E IrrE N-terminal-like domain
COHLBPCN_01335 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
COHLBPCN_01337 5.9e-157 xkdB K sequence-specific DNA binding
COHLBPCN_01338 6.4e-119 xkdC L Bacterial dnaA protein
COHLBPCN_01341 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
COHLBPCN_01342 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
COHLBPCN_01343 4.8e-140 xtmA L phage terminase small subunit
COHLBPCN_01344 9.6e-255 xtmB S phage terminase, large subunit
COHLBPCN_01345 5.4e-286 yqbA S portal protein
COHLBPCN_01346 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
COHLBPCN_01347 5.8e-169 xkdG S Phage capsid family
COHLBPCN_01348 5.5e-65 yqbG S Protein of unknown function (DUF3199)
COHLBPCN_01349 8.7e-65 yqbH S Domain of unknown function (DUF3599)
COHLBPCN_01350 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
COHLBPCN_01351 1.9e-77 xkdJ
COHLBPCN_01352 2.5e-256 xkdK S Phage tail sheath C-terminal domain
COHLBPCN_01353 6.1e-76 xkdM S Phage tail tube protein
COHLBPCN_01354 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
COHLBPCN_01355 0.0 xkdO L Transglycosylase SLT domain
COHLBPCN_01356 3.7e-122 xkdP S Lysin motif
COHLBPCN_01357 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
COHLBPCN_01358 2.1e-39 xkdR S Protein of unknown function (DUF2577)
COHLBPCN_01359 9.6e-71 xkdS S Protein of unknown function (DUF2634)
COHLBPCN_01360 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
COHLBPCN_01361 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
COHLBPCN_01362 6.7e-41
COHLBPCN_01363 0.0
COHLBPCN_01364 2.6e-55 xkdW S XkdW protein
COHLBPCN_01365 1.7e-23 xkdX
COHLBPCN_01366 1.2e-154 xepA
COHLBPCN_01367 2.8e-39 xhlA S Haemolysin XhlA
COHLBPCN_01368 9.3e-40 xhlB S SPP1 phage holin
COHLBPCN_01369 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COHLBPCN_01370 6.7e-23 spoIISB S Stage II sporulation protein SB
COHLBPCN_01371 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
COHLBPCN_01372 5.8e-175 pit P phosphate transporter
COHLBPCN_01373 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
COHLBPCN_01374 9.4e-242 steT E amino acid
COHLBPCN_01375 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
COHLBPCN_01377 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COHLBPCN_01378 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COHLBPCN_01380 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COHLBPCN_01381 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
COHLBPCN_01382 7.9e-154 dppA E D-aminopeptidase
COHLBPCN_01383 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COHLBPCN_01384 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COHLBPCN_01385 3.4e-191 dppD P Belongs to the ABC transporter superfamily
COHLBPCN_01386 0.0 dppE E ABC transporter substrate-binding protein
COHLBPCN_01388 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
COHLBPCN_01389 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
COHLBPCN_01390 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
COHLBPCN_01391 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
COHLBPCN_01392 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
COHLBPCN_01393 5.3e-161 ykgA E Amidinotransferase
COHLBPCN_01394 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
COHLBPCN_01395 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
COHLBPCN_01396 1e-07
COHLBPCN_01397 5.4e-130 ykjA S Protein of unknown function (DUF421)
COHLBPCN_01398 1e-98 ykkA S Protein of unknown function (DUF664)
COHLBPCN_01399 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
COHLBPCN_01400 3.5e-55 ykkC P Multidrug resistance protein
COHLBPCN_01401 1.1e-50 ykkD P Multidrug resistance protein
COHLBPCN_01402 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
COHLBPCN_01403 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COHLBPCN_01404 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COHLBPCN_01405 1.3e-70 ohrA O Organic hydroperoxide resistance protein
COHLBPCN_01406 3.9e-75 ohrR K COG1846 Transcriptional regulators
COHLBPCN_01407 8.4e-72 ohrB O Organic hydroperoxide resistance protein
COHLBPCN_01409 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
COHLBPCN_01410 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COHLBPCN_01411 1.7e-176 isp O Belongs to the peptidase S8 family
COHLBPCN_01412 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COHLBPCN_01413 1.8e-136 ykoC P Cobalt transport protein
COHLBPCN_01414 4.6e-311 P ABC transporter, ATP-binding protein
COHLBPCN_01415 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
COHLBPCN_01416 7.9e-111 ykoF S YKOF-related Family
COHLBPCN_01417 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_01418 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
COHLBPCN_01419 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
COHLBPCN_01420 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
COHLBPCN_01423 2.2e-222 mgtE P Acts as a magnesium transporter
COHLBPCN_01424 1.4e-53 tnrA K transcriptional
COHLBPCN_01425 5.9e-18
COHLBPCN_01426 6.9e-26 ykoL
COHLBPCN_01427 1.3e-81 mhqR K transcriptional
COHLBPCN_01428 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
COHLBPCN_01429 3.7e-99 ykoP G polysaccharide deacetylase
COHLBPCN_01430 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
COHLBPCN_01431 0.0 ykoS
COHLBPCN_01432 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COHLBPCN_01433 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
COHLBPCN_01434 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
COHLBPCN_01435 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
COHLBPCN_01436 1.4e-116 ykoX S membrane-associated protein
COHLBPCN_01437 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
COHLBPCN_01438 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COHLBPCN_01439 8.2e-117 rsgI S Anti-sigma factor N-terminus
COHLBPCN_01440 1.9e-26 sspD S small acid-soluble spore protein
COHLBPCN_01441 1.5e-124 ykrK S Domain of unknown function (DUF1836)
COHLBPCN_01442 7e-156 htpX O Belongs to the peptidase M48B family
COHLBPCN_01443 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
COHLBPCN_01444 1.2e-10 ydfR S Protein of unknown function (DUF421)
COHLBPCN_01445 4.5e-22 ykzE
COHLBPCN_01446 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
COHLBPCN_01447 0.0 kinE 2.7.13.3 T Histidine kinase
COHLBPCN_01448 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COHLBPCN_01450 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
COHLBPCN_01451 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
COHLBPCN_01452 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
COHLBPCN_01453 8e-232 mtnE 2.6.1.83 E Aminotransferase
COHLBPCN_01454 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
COHLBPCN_01455 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
COHLBPCN_01456 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
COHLBPCN_01457 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
COHLBPCN_01458 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
COHLBPCN_01459 6.4e-09 S Spo0E like sporulation regulatory protein
COHLBPCN_01460 1.4e-64 eag
COHLBPCN_01461 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
COHLBPCN_01462 1.3e-75 ykvE K transcriptional
COHLBPCN_01463 2.5e-125 motB N Flagellar motor protein
COHLBPCN_01464 2.7e-138 motA N flagellar motor
COHLBPCN_01465 0.0 clpE O Belongs to the ClpA ClpB family
COHLBPCN_01466 8.7e-182 ykvI S membrane
COHLBPCN_01467 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
COHLBPCN_01468 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
COHLBPCN_01469 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
COHLBPCN_01470 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
COHLBPCN_01471 2e-61 ykvN K Transcriptional regulator
COHLBPCN_01472 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
COHLBPCN_01473 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
COHLBPCN_01474 1.2e-35 3.5.1.104 M LysM domain
COHLBPCN_01475 8.5e-133 G Glycosyl hydrolases family 18
COHLBPCN_01476 5.6e-46 ykvR S Protein of unknown function (DUF3219)
COHLBPCN_01477 6e-25 ykvS S protein conserved in bacteria
COHLBPCN_01478 2.8e-28
COHLBPCN_01479 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
COHLBPCN_01480 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COHLBPCN_01481 4.9e-90 stoA CO thiol-disulfide
COHLBPCN_01482 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
COHLBPCN_01483 3.8e-09
COHLBPCN_01484 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
COHLBPCN_01486 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
COHLBPCN_01488 4.5e-128 glcT K antiterminator
COHLBPCN_01489 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COHLBPCN_01490 2.1e-39 ptsH G phosphocarrier protein HPr
COHLBPCN_01491 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COHLBPCN_01492 7.2e-39 splA S Transcriptional regulator
COHLBPCN_01493 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
COHLBPCN_01494 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COHLBPCN_01495 2e-264 mcpC NT chemotaxis protein
COHLBPCN_01496 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
COHLBPCN_01497 8e-124 ykwD J protein with SCP PR1 domains
COHLBPCN_01498 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
COHLBPCN_01499 0.0 pilS 2.7.13.3 T Histidine kinase
COHLBPCN_01500 8e-224 patA 2.6.1.1 E Aminotransferase
COHLBPCN_01501 2.2e-15
COHLBPCN_01502 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
COHLBPCN_01503 1.7e-84 ykyB S YkyB-like protein
COHLBPCN_01504 1.6e-238 ykuC EGP Major facilitator Superfamily
COHLBPCN_01505 4.6e-88 ykuD S protein conserved in bacteria
COHLBPCN_01506 9.4e-166 ykuE S Metallophosphoesterase
COHLBPCN_01507 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_01508 0.0 3.2.1.132 M Putative peptidoglycan binding domain
COHLBPCN_01509 1.7e-93 M Peptidoglycan-binding domain 1 protein
COHLBPCN_01511 5.2e-234 ykuI T Diguanylate phosphodiesterase
COHLBPCN_01512 3.9e-37 ykuJ S protein conserved in bacteria
COHLBPCN_01513 4.4e-94 ykuK S Ribonuclease H-like
COHLBPCN_01514 3.9e-27 ykzF S Antirepressor AbbA
COHLBPCN_01515 1.6e-76 ykuL S CBS domain
COHLBPCN_01516 3.5e-168 ccpC K Transcriptional regulator
COHLBPCN_01517 5.7e-88 fld C Flavodoxin domain
COHLBPCN_01518 3.2e-177 ykuO
COHLBPCN_01519 3.2e-80 fld C Flavodoxin
COHLBPCN_01520 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COHLBPCN_01521 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COHLBPCN_01522 9e-37 ykuS S Belongs to the UPF0180 family
COHLBPCN_01523 8.8e-142 ykuT M Mechanosensitive ion channel
COHLBPCN_01524 3.9e-101 ykuU O Alkyl hydroperoxide reductase
COHLBPCN_01525 4.4e-82 ykuV CO thiol-disulfide
COHLBPCN_01526 5.8e-95 rok K Repressor of ComK
COHLBPCN_01527 2.9e-147 yknT
COHLBPCN_01528 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
COHLBPCN_01529 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
COHLBPCN_01530 8.1e-246 moeA 2.10.1.1 H molybdopterin
COHLBPCN_01531 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
COHLBPCN_01532 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
COHLBPCN_01533 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
COHLBPCN_01534 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
COHLBPCN_01535 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
COHLBPCN_01536 1e-117 yknW S Yip1 domain
COHLBPCN_01537 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COHLBPCN_01538 2.5e-124 macB V ABC transporter, ATP-binding protein
COHLBPCN_01539 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
COHLBPCN_01540 3.1e-136 fruR K Transcriptional regulator
COHLBPCN_01541 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
COHLBPCN_01542 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
COHLBPCN_01543 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
COHLBPCN_01544 8.1e-39 ykoA
COHLBPCN_01545 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
COHLBPCN_01546 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COHLBPCN_01547 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
COHLBPCN_01548 1.1e-12 S Uncharacterized protein YkpC
COHLBPCN_01549 7.7e-183 mreB D Rod-share determining protein MreBH
COHLBPCN_01550 1.5e-43 abrB K of stationary sporulation gene expression
COHLBPCN_01551 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
COHLBPCN_01552 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
COHLBPCN_01553 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
COHLBPCN_01554 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
COHLBPCN_01555 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COHLBPCN_01556 8.2e-31 ykzG S Belongs to the UPF0356 family
COHLBPCN_01557 1.4e-147 ykrA S hydrolases of the HAD superfamily
COHLBPCN_01558 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COHLBPCN_01560 2e-115 recN L Putative cell-wall binding lipoprotein
COHLBPCN_01561 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
COHLBPCN_01562 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
COHLBPCN_01563 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COHLBPCN_01564 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
COHLBPCN_01565 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
COHLBPCN_01566 3.5e-277 speA 4.1.1.19 E Arginine
COHLBPCN_01567 1.6e-42 yktA S Belongs to the UPF0223 family
COHLBPCN_01568 7.1e-118 yktB S Belongs to the UPF0637 family
COHLBPCN_01569 7.1e-26 ykzI
COHLBPCN_01570 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
COHLBPCN_01571 6.9e-78 ykzC S Acetyltransferase (GNAT) family
COHLBPCN_01572 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
COHLBPCN_01573 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
COHLBPCN_01574 0.0 ylaA
COHLBPCN_01575 2.7e-42 ylaB
COHLBPCN_01576 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_01577 1.2e-11 sigC S Putative zinc-finger
COHLBPCN_01578 1.8e-38 ylaE
COHLBPCN_01579 8.2e-22 S Family of unknown function (DUF5325)
COHLBPCN_01580 0.0 typA T GTP-binding protein TypA
COHLBPCN_01581 4.2e-47 ylaH S YlaH-like protein
COHLBPCN_01582 2.5e-32 ylaI S protein conserved in bacteria
COHLBPCN_01583 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
COHLBPCN_01584 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
COHLBPCN_01585 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
COHLBPCN_01586 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
COHLBPCN_01587 8.7e-44 ylaN S Belongs to the UPF0358 family
COHLBPCN_01588 4.5e-214 ftsW D Belongs to the SEDS family
COHLBPCN_01589 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
COHLBPCN_01590 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
COHLBPCN_01591 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
COHLBPCN_01592 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
COHLBPCN_01593 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
COHLBPCN_01594 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
COHLBPCN_01595 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
COHLBPCN_01596 3e-167 ctaG S cytochrome c oxidase
COHLBPCN_01597 7e-62 ylbA S YugN-like family
COHLBPCN_01598 2.6e-74 ylbB T COG0517 FOG CBS domain
COHLBPCN_01599 3e-201 ylbC S protein with SCP PR1 domains
COHLBPCN_01600 4.1e-63 ylbD S Putative coat protein
COHLBPCN_01601 6.7e-37 ylbE S YlbE-like protein
COHLBPCN_01602 1.8e-75 ylbF S Belongs to the UPF0342 family
COHLBPCN_01603 7.5e-39 ylbG S UPF0298 protein
COHLBPCN_01604 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
COHLBPCN_01605 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COHLBPCN_01606 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
COHLBPCN_01607 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
COHLBPCN_01608 6.8e-187 ylbL T Belongs to the peptidase S16 family
COHLBPCN_01609 2.8e-235 ylbM S Belongs to the UPF0348 family
COHLBPCN_01611 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
COHLBPCN_01612 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COHLBPCN_01613 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
COHLBPCN_01614 4e-89 ylbP K n-acetyltransferase
COHLBPCN_01615 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COHLBPCN_01616 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
COHLBPCN_01617 2.9e-78 mraZ K Belongs to the MraZ family
COHLBPCN_01618 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COHLBPCN_01619 3.7e-44 ftsL D Essential cell division protein
COHLBPCN_01620 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
COHLBPCN_01621 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
COHLBPCN_01622 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COHLBPCN_01623 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COHLBPCN_01624 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COHLBPCN_01625 5.7e-186 spoVE D Belongs to the SEDS family
COHLBPCN_01626 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COHLBPCN_01627 5.3e-167 murB 1.3.1.98 M cell wall formation
COHLBPCN_01628 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COHLBPCN_01629 2.4e-103 ylxW S protein conserved in bacteria
COHLBPCN_01630 1e-102 ylxX S protein conserved in bacteria
COHLBPCN_01631 6.2e-58 sbp S small basic protein
COHLBPCN_01632 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COHLBPCN_01633 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COHLBPCN_01634 0.0 bpr O COG1404 Subtilisin-like serine proteases
COHLBPCN_01635 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
COHLBPCN_01636 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COHLBPCN_01637 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COHLBPCN_01638 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
COHLBPCN_01639 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
COHLBPCN_01640 2.4e-37 ylmC S sporulation protein
COHLBPCN_01641 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
COHLBPCN_01642 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COHLBPCN_01643 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COHLBPCN_01644 1.3e-39 yggT S membrane
COHLBPCN_01645 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
COHLBPCN_01646 2.6e-67 divIVA D Cell division initiation protein
COHLBPCN_01647 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COHLBPCN_01648 1.3e-63 dksA T COG1734 DnaK suppressor protein
COHLBPCN_01649 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COHLBPCN_01650 1.1e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COHLBPCN_01651 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COHLBPCN_01652 9e-232 pyrP F Xanthine uracil
COHLBPCN_01653 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COHLBPCN_01654 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COHLBPCN_01655 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COHLBPCN_01656 0.0 carB 6.3.5.5 F Belongs to the CarB family
COHLBPCN_01657 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
COHLBPCN_01658 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COHLBPCN_01659 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COHLBPCN_01660 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COHLBPCN_01662 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
COHLBPCN_01663 1.1e-179 cysP P phosphate transporter
COHLBPCN_01664 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
COHLBPCN_01665 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
COHLBPCN_01666 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
COHLBPCN_01667 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
COHLBPCN_01668 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
COHLBPCN_01669 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
COHLBPCN_01670 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
COHLBPCN_01671 2.4e-156 yloC S stress-induced protein
COHLBPCN_01672 1.5e-40 ylzA S Belongs to the UPF0296 family
COHLBPCN_01673 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
COHLBPCN_01674 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COHLBPCN_01675 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COHLBPCN_01676 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COHLBPCN_01677 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COHLBPCN_01678 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COHLBPCN_01679 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COHLBPCN_01680 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
COHLBPCN_01681 2.4e-141 stp 3.1.3.16 T phosphatase
COHLBPCN_01682 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
COHLBPCN_01683 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COHLBPCN_01684 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COHLBPCN_01685 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
COHLBPCN_01686 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COHLBPCN_01687 5.5e-59 asp S protein conserved in bacteria
COHLBPCN_01688 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
COHLBPCN_01689 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
COHLBPCN_01690 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
COHLBPCN_01691 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COHLBPCN_01692 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
COHLBPCN_01693 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COHLBPCN_01694 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
COHLBPCN_01695 6.1e-129 IQ reductase
COHLBPCN_01696 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COHLBPCN_01697 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COHLBPCN_01698 0.0 smc D Required for chromosome condensation and partitioning
COHLBPCN_01699 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COHLBPCN_01700 2.9e-87
COHLBPCN_01701 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COHLBPCN_01702 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COHLBPCN_01703 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COHLBPCN_01704 1.2e-36 ylqC S Belongs to the UPF0109 family
COHLBPCN_01705 1.3e-61 ylqD S YlqD protein
COHLBPCN_01706 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COHLBPCN_01707 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COHLBPCN_01708 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COHLBPCN_01709 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COHLBPCN_01710 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COHLBPCN_01711 8.5e-291 ylqG
COHLBPCN_01712 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
COHLBPCN_01713 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
COHLBPCN_01714 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
COHLBPCN_01715 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
COHLBPCN_01716 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COHLBPCN_01717 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
COHLBPCN_01718 2.5e-169 xerC L tyrosine recombinase XerC
COHLBPCN_01719 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COHLBPCN_01720 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COHLBPCN_01721 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
COHLBPCN_01722 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
COHLBPCN_01723 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
COHLBPCN_01724 1.9e-31 fliE N Flagellar hook-basal body
COHLBPCN_01725 2.4e-255 fliF N The M ring may be actively involved in energy transduction
COHLBPCN_01726 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
COHLBPCN_01727 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
COHLBPCN_01728 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
COHLBPCN_01729 1.5e-69 fliJ N Flagellar biosynthesis chaperone
COHLBPCN_01730 7.7e-37 ylxF S MgtE intracellular N domain
COHLBPCN_01731 1.2e-221 fliK N Flagellar hook-length control protein
COHLBPCN_01732 1.7e-72 flgD N Flagellar basal body rod modification protein
COHLBPCN_01733 8.2e-140 flgG N Flagellar basal body rod
COHLBPCN_01734 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
COHLBPCN_01735 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
COHLBPCN_01736 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
COHLBPCN_01737 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
COHLBPCN_01738 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
COHLBPCN_01739 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
COHLBPCN_01740 2.2e-36 fliQ N Role in flagellar biosynthesis
COHLBPCN_01741 3.6e-132 fliR N Flagellar biosynthetic protein FliR
COHLBPCN_01742 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
COHLBPCN_01743 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
COHLBPCN_01744 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
COHLBPCN_01745 7.5e-158 flhG D Belongs to the ParA family
COHLBPCN_01746 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
COHLBPCN_01747 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
COHLBPCN_01748 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
COHLBPCN_01749 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
COHLBPCN_01750 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
COHLBPCN_01751 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COHLBPCN_01752 4.3e-78 ylxL
COHLBPCN_01753 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
COHLBPCN_01754 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COHLBPCN_01755 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COHLBPCN_01756 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COHLBPCN_01757 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COHLBPCN_01758 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
COHLBPCN_01759 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COHLBPCN_01760 7.7e-233 rasP M zinc metalloprotease
COHLBPCN_01761 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COHLBPCN_01762 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COHLBPCN_01763 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
COHLBPCN_01764 1.1e-203 nusA K Participates in both transcription termination and antitermination
COHLBPCN_01765 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
COHLBPCN_01766 3.1e-47 ylxQ J ribosomal protein
COHLBPCN_01767 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COHLBPCN_01768 3e-44 ylxP S protein conserved in bacteria
COHLBPCN_01769 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COHLBPCN_01770 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COHLBPCN_01771 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COHLBPCN_01772 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COHLBPCN_01773 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
COHLBPCN_01774 4.2e-183 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
COHLBPCN_01775 4.4e-233 pepR S Belongs to the peptidase M16 family
COHLBPCN_01776 2.6e-42 ymxH S YlmC YmxH family
COHLBPCN_01777 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
COHLBPCN_01778 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
COHLBPCN_01779 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COHLBPCN_01780 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
COHLBPCN_01781 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COHLBPCN_01782 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COHLBPCN_01783 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
COHLBPCN_01784 4.4e-32 S YlzJ-like protein
COHLBPCN_01785 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
COHLBPCN_01786 1.4e-133 ymfC K Transcriptional regulator
COHLBPCN_01787 1.5e-206 ymfD EGP Major facilitator Superfamily
COHLBPCN_01788 2.6e-236 ymfF S Peptidase M16
COHLBPCN_01789 1.4e-242 ymfH S zinc protease
COHLBPCN_01790 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
COHLBPCN_01791 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
COHLBPCN_01792 2.7e-143 ymfK S Protein of unknown function (DUF3388)
COHLBPCN_01793 1.9e-124 ymfM S protein conserved in bacteria
COHLBPCN_01794 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COHLBPCN_01795 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
COHLBPCN_01796 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COHLBPCN_01797 1e-215 pbpX V Beta-lactamase
COHLBPCN_01798 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
COHLBPCN_01799 1.9e-152 ymdB S protein conserved in bacteria
COHLBPCN_01800 1.2e-36 spoVS S Stage V sporulation protein S
COHLBPCN_01801 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
COHLBPCN_01802 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
COHLBPCN_01803 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
COHLBPCN_01804 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
COHLBPCN_01805 2.2e-88 cotE S Spore coat protein
COHLBPCN_01806 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COHLBPCN_01807 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COHLBPCN_01808 2.3e-70 S Regulatory protein YrvL
COHLBPCN_01810 1.2e-97 ymcC S Membrane
COHLBPCN_01811 4.4e-109 pksA K Transcriptional regulator
COHLBPCN_01812 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
COHLBPCN_01813 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
COHLBPCN_01814 2.4e-186 pksD Q Acyl transferase domain
COHLBPCN_01815 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
COHLBPCN_01816 1.4e-37 acpK IQ Phosphopantetheine attachment site
COHLBPCN_01817 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COHLBPCN_01818 1.3e-245 pksG 2.3.3.10 I synthase
COHLBPCN_01819 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
COHLBPCN_01820 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
COHLBPCN_01821 0.0 rhiB IQ polyketide synthase
COHLBPCN_01822 0.0 pfaA Q Polyketide synthase of type I
COHLBPCN_01823 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
COHLBPCN_01824 0.0 dhbF IQ polyketide synthase
COHLBPCN_01825 0.0 pks13 HQ Beta-ketoacyl synthase
COHLBPCN_01826 2.5e-233 cypA C Cytochrome P450
COHLBPCN_01827 1.2e-61 ymzB
COHLBPCN_01828 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
COHLBPCN_01829 4.6e-252 aprX O Belongs to the peptidase S8 family
COHLBPCN_01830 2.1e-126 ymaC S Replication protein
COHLBPCN_01831 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
COHLBPCN_01832 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
COHLBPCN_01833 4.9e-51 ebrA P Small Multidrug Resistance protein
COHLBPCN_01835 2.1e-46 ymaF S YmaF family
COHLBPCN_01836 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COHLBPCN_01837 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
COHLBPCN_01838 6.3e-23
COHLBPCN_01839 4.5e-22 ymzA
COHLBPCN_01840 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
COHLBPCN_01841 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COHLBPCN_01842 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COHLBPCN_01843 2e-109 ymaB
COHLBPCN_01844 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COHLBPCN_01845 1.7e-176 spoVK O stage V sporulation protein K
COHLBPCN_01846 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COHLBPCN_01847 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
COHLBPCN_01848 1.1e-68 glnR K transcriptional
COHLBPCN_01849 7e-261 glnA 6.3.1.2 E glutamine synthetase
COHLBPCN_01850 5e-10
COHLBPCN_01851 2.5e-32
COHLBPCN_01852 5.8e-39
COHLBPCN_01853 6.8e-80 G regulation of fungal-type cell wall biogenesis
COHLBPCN_01854 4.9e-145 ynaC
COHLBPCN_01855 2e-99 ynaD J Acetyltransferase (GNAT) domain
COHLBPCN_01856 1.9e-123 ynaE S Domain of unknown function (DUF3885)
COHLBPCN_01857 6.4e-60 ynaF
COHLBPCN_01860 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
COHLBPCN_01861 2.7e-255 xynT G MFS/sugar transport protein
COHLBPCN_01862 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
COHLBPCN_01863 1e-215 xylR GK ROK family
COHLBPCN_01864 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
COHLBPCN_01865 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
COHLBPCN_01866 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
COHLBPCN_01867 3.5e-247 iolT EGP Major facilitator Superfamily
COHLBPCN_01868 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COHLBPCN_01869 6.3e-84 yncE S Protein of unknown function (DUF2691)
COHLBPCN_01870 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
COHLBPCN_01871 5.2e-15
COHLBPCN_01874 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COHLBPCN_01876 1.3e-134 S Domain of unknown function, YrpD
COHLBPCN_01879 7.9e-25 tatA U protein secretion
COHLBPCN_01880 1.8e-71
COHLBPCN_01881 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
COHLBPCN_01884 5.7e-286 gerAA EG Spore germination protein
COHLBPCN_01885 2.9e-196 gerAB U Spore germination
COHLBPCN_01886 4.2e-220 gerLC S Spore germination protein
COHLBPCN_01887 7.7e-154 yndG S DoxX-like family
COHLBPCN_01888 2.6e-117 yndH S Domain of unknown function (DUF4166)
COHLBPCN_01889 0.0 yndJ S YndJ-like protein
COHLBPCN_01891 8.6e-139 yndL S Replication protein
COHLBPCN_01892 5.8e-74 yndM S Protein of unknown function (DUF2512)
COHLBPCN_01893 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
COHLBPCN_01895 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COHLBPCN_01896 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
COHLBPCN_01897 9.2e-113 yneB L resolvase
COHLBPCN_01898 1.3e-32 ynzC S UPF0291 protein
COHLBPCN_01899 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COHLBPCN_01900 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
COHLBPCN_01901 1.8e-28 yneF S UPF0154 protein
COHLBPCN_01902 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
COHLBPCN_01903 7.1e-127 ccdA O cytochrome c biogenesis protein
COHLBPCN_01904 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
COHLBPCN_01905 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
COHLBPCN_01906 4.2e-74 yneK S Protein of unknown function (DUF2621)
COHLBPCN_01907 4.1e-65 hspX O Spore coat protein
COHLBPCN_01908 3.9e-19 sspP S Belongs to the SspP family
COHLBPCN_01909 2.2e-14 sspO S Belongs to the SspO family
COHLBPCN_01910 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
COHLBPCN_01911 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
COHLBPCN_01913 3.1e-08 sspN S Small acid-soluble spore protein N family
COHLBPCN_01914 3.9e-35 tlp S Belongs to the Tlp family
COHLBPCN_01915 1.2e-73 yneP S Thioesterase-like superfamily
COHLBPCN_01916 1.3e-53 yneQ
COHLBPCN_01917 4.1e-49 yneR S Belongs to the HesB IscA family
COHLBPCN_01918 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COHLBPCN_01919 6.6e-69 yccU S CoA-binding protein
COHLBPCN_01920 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COHLBPCN_01921 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COHLBPCN_01922 2.3e-12
COHLBPCN_01923 1.3e-57 ynfC
COHLBPCN_01924 8.2e-252 agcS E Sodium alanine symporter
COHLBPCN_01925 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
COHLBPCN_01927 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
COHLBPCN_01928 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
COHLBPCN_01929 2.4e-80 yngA S membrane
COHLBPCN_01930 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COHLBPCN_01931 5.5e-104 yngC S membrane-associated protein
COHLBPCN_01932 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
COHLBPCN_01933 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
COHLBPCN_01934 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
COHLBPCN_01935 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
COHLBPCN_01936 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
COHLBPCN_01937 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
COHLBPCN_01938 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COHLBPCN_01939 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
COHLBPCN_01940 1.8e-31 S Family of unknown function (DUF5367)
COHLBPCN_01941 1.3e-306 yngK T Glycosyl hydrolase-like 10
COHLBPCN_01942 2.8e-64 yngL S Protein of unknown function (DUF1360)
COHLBPCN_01943 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
COHLBPCN_01944 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_01945 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_01946 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_01947 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_01948 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
COHLBPCN_01949 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
COHLBPCN_01950 2.3e-246 yoeA V MATE efflux family protein
COHLBPCN_01951 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
COHLBPCN_01953 2.2e-96 L Integrase
COHLBPCN_01954 3e-34 yoeD G Helix-turn-helix domain
COHLBPCN_01955 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
COHLBPCN_01956 2.5e-158 gltR1 K Transcriptional regulator
COHLBPCN_01957 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
COHLBPCN_01958 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
COHLBPCN_01959 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
COHLBPCN_01960 7.8e-155 gltC K Transcriptional regulator
COHLBPCN_01961 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COHLBPCN_01962 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COHLBPCN_01963 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
COHLBPCN_01964 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_01965 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
COHLBPCN_01966 3.1e-144 yoxB
COHLBPCN_01967 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
COHLBPCN_01968 6.2e-235 yoaB EGP Major facilitator Superfamily
COHLBPCN_01969 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
COHLBPCN_01970 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COHLBPCN_01971 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COHLBPCN_01972 1.9e-33 yoaF
COHLBPCN_01973 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
COHLBPCN_01974 7e-14
COHLBPCN_01975 1.5e-38 S Protein of unknown function (DUF4025)
COHLBPCN_01976 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
COHLBPCN_01977 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
COHLBPCN_01978 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
COHLBPCN_01979 2.3e-111 yoaK S Membrane
COHLBPCN_01980 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
COHLBPCN_01981 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
COHLBPCN_01983 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
COHLBPCN_01985 1.5e-146 yoaP 3.1.3.18 K YoaP-like
COHLBPCN_01986 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
COHLBPCN_01987 4.1e-89
COHLBPCN_01988 2.4e-172 yoaR V vancomycin resistance protein
COHLBPCN_01989 4.3e-75 yoaS S Protein of unknown function (DUF2975)
COHLBPCN_01990 4.2e-37 yozG K Transcriptional regulator
COHLBPCN_01991 1.1e-149 yoaT S Protein of unknown function (DUF817)
COHLBPCN_01992 8.6e-159 yoaU K LysR substrate binding domain
COHLBPCN_01993 6e-160 yijE EG EamA-like transporter family
COHLBPCN_01994 3.7e-78 yoaW
COHLBPCN_01995 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
COHLBPCN_01996 2.3e-170 bla 3.5.2.6 V beta-lactamase
COHLBPCN_02000 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
COHLBPCN_02001 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
COHLBPCN_02002 1.4e-37 S TM2 domain
COHLBPCN_02003 5.7e-58 K Helix-turn-helix
COHLBPCN_02005 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
COHLBPCN_02006 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
COHLBPCN_02007 1.8e-178 yobF
COHLBPCN_02012 1.7e-207 S aspartate phosphatase
COHLBPCN_02014 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COHLBPCN_02015 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COHLBPCN_02016 2.6e-38 S YolD-like protein
COHLBPCN_02017 1.2e-49
COHLBPCN_02018 0.0 K Psort location Cytoplasmic, score
COHLBPCN_02019 2.7e-157 yobJ
COHLBPCN_02020 3e-86 S SMI1-KNR4 cell-wall
COHLBPCN_02021 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
COHLBPCN_02022 7.9e-105 yokH G SMI1 / KNR4 family
COHLBPCN_02023 9.5e-280 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
COHLBPCN_02024 0.0 yobO M Pectate lyase superfamily protein
COHLBPCN_02025 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
COHLBPCN_02026 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
COHLBPCN_02027 2.5e-143 yobR 2.3.1.1 J FR47-like protein
COHLBPCN_02028 3e-99 yobS K Transcriptional regulator
COHLBPCN_02029 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
COHLBPCN_02030 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
COHLBPCN_02031 9e-178 yobV K WYL domain
COHLBPCN_02032 2.5e-95 yobW
COHLBPCN_02033 1e-51 czrA K transcriptional
COHLBPCN_02034 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
COHLBPCN_02035 1.5e-92 yozB S membrane
COHLBPCN_02036 2.2e-145
COHLBPCN_02037 1.9e-94 yocC
COHLBPCN_02038 6.9e-189 yocD 3.4.17.13 V peptidase S66
COHLBPCN_02039 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
COHLBPCN_02040 3.2e-198 desK 2.7.13.3 T Histidine kinase
COHLBPCN_02041 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COHLBPCN_02042 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
COHLBPCN_02043 0.0 recQ 3.6.4.12 L DNA helicase
COHLBPCN_02044 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COHLBPCN_02045 3.3e-83 dksA T general stress protein
COHLBPCN_02046 6.4e-54 yocL
COHLBPCN_02047 6.6e-34
COHLBPCN_02048 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
COHLBPCN_02049 1.1e-40 yozN
COHLBPCN_02050 1.9e-36 yocN
COHLBPCN_02051 4.2e-56 yozO S Bacterial PH domain
COHLBPCN_02052 2.7e-31 yozC
COHLBPCN_02053 5.8e-288 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
COHLBPCN_02054 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
COHLBPCN_02055 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
COHLBPCN_02056 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
COHLBPCN_02057 5.1e-168 yocS S -transporter
COHLBPCN_02058 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
COHLBPCN_02059 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
COHLBPCN_02060 0.0 yojO P Von Willebrand factor
COHLBPCN_02061 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
COHLBPCN_02062 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
COHLBPCN_02063 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
COHLBPCN_02064 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
COHLBPCN_02065 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COHLBPCN_02067 4.2e-245 norM V Multidrug efflux pump
COHLBPCN_02068 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COHLBPCN_02069 2.1e-125 yojG S deacetylase
COHLBPCN_02070 2.2e-60 yojF S Protein of unknown function (DUF1806)
COHLBPCN_02071 1.5e-43
COHLBPCN_02072 3.5e-163 rarD S -transporter
COHLBPCN_02073 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
COHLBPCN_02074 3.4e-09
COHLBPCN_02075 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
COHLBPCN_02076 3.8e-66 yodA S tautomerase
COHLBPCN_02077 1.7e-57 yodB K transcriptional
COHLBPCN_02078 4.8e-108 yodC C nitroreductase
COHLBPCN_02079 3.8e-113 mhqD S Carboxylesterase
COHLBPCN_02080 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
COHLBPCN_02081 6.2e-28 S Protein of unknown function (DUF3311)
COHLBPCN_02082 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COHLBPCN_02083 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
COHLBPCN_02084 1.7e-128 yodH Q Methyltransferase
COHLBPCN_02085 5.2e-24 yodI
COHLBPCN_02086 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
COHLBPCN_02087 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
COHLBPCN_02088 5.3e-09
COHLBPCN_02089 3.6e-54 yodL S YodL-like
COHLBPCN_02090 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
COHLBPCN_02091 2.8e-24 yozD S YozD-like protein
COHLBPCN_02093 1.4e-124 yodN
COHLBPCN_02094 1.4e-36 yozE S Belongs to the UPF0346 family
COHLBPCN_02095 2.9e-47 yokU S YokU-like protein, putative antitoxin
COHLBPCN_02096 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
COHLBPCN_02097 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
COHLBPCN_02098 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
COHLBPCN_02099 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
COHLBPCN_02100 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
COHLBPCN_02101 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COHLBPCN_02104 2.9e-145 yiiD K acetyltransferase
COHLBPCN_02105 1e-256 cgeD M maturation of the outermost layer of the spore
COHLBPCN_02106 3.5e-38 cgeC
COHLBPCN_02107 1.2e-65 cgeA
COHLBPCN_02108 3.3e-188 cgeB S Spore maturation protein
COHLBPCN_02109 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
COHLBPCN_02110 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
COHLBPCN_02112 3.6e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COHLBPCN_02113 1.4e-10 K Cro/C1-type HTH DNA-binding domain
COHLBPCN_02121 1.9e-168 S Calcineurin-like phosphoesterase
COHLBPCN_02122 2.5e-30 sspB S spore protein
COHLBPCN_02127 8.9e-83 yosT L Bacterial transcription activator, effector binding domain
COHLBPCN_02128 2.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
COHLBPCN_02129 6.1e-38 O Glutaredoxin
COHLBPCN_02130 2.8e-66 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COHLBPCN_02131 3.3e-97 L HNH endonuclease
COHLBPCN_02132 1e-107 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COHLBPCN_02133 8.1e-126 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COHLBPCN_02134 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COHLBPCN_02135 2.3e-117 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COHLBPCN_02136 5.1e-66 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
COHLBPCN_02153 1.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
COHLBPCN_02155 1.2e-96 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
COHLBPCN_02156 5.9e-88 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
COHLBPCN_02161 9.9e-115 DR0488 S protein conserved in bacteria
COHLBPCN_02162 0.0 2.7.7.7 L DNA polymerase
COHLBPCN_02163 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COHLBPCN_02164 1.2e-224 L DNA primase activity
COHLBPCN_02165 3.6e-285 3.6.4.12 J DnaB-like helicase C terminal domain
COHLBPCN_02166 1.4e-86
COHLBPCN_02167 7.6e-180 L AAA domain
COHLBPCN_02168 1.3e-170
COHLBPCN_02173 0.0 M Parallel beta-helix repeats
COHLBPCN_02174 7.7e-149 S Pfam:DUF867
COHLBPCN_02177 1e-130 yoqW S Belongs to the SOS response-associated peptidase family
COHLBPCN_02178 2.4e-155 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
COHLBPCN_02179 2.3e-77
COHLBPCN_02186 1e-44
COHLBPCN_02188 1.5e-97 S Protein of unknown function (DUF1273)
COHLBPCN_02190 3e-78 yoqH M LysM domain
COHLBPCN_02193 8.8e-12 S Protein of unknown function (DUF2815)
COHLBPCN_02194 6.2e-137 kilA S Phage regulatory protein Rha (Phage_pRha)
COHLBPCN_02205 1.1e-33 K Transcriptional regulator
COHLBPCN_02206 2.1e-177
COHLBPCN_02207 6e-263 S DNA-sulfur modification-associated
COHLBPCN_02208 6.8e-198 L Belongs to the 'phage' integrase family
COHLBPCN_02213 6.6e-106
COHLBPCN_02215 1.2e-86
COHLBPCN_02216 1.1e-96 S Super-infection exclusion protein B
COHLBPCN_02221 1.1e-07 ywlA S Uncharacterised protein family (UPF0715)
COHLBPCN_02222 3.8e-259
COHLBPCN_02223 4.6e-35 K Cro/C1-type HTH DNA-binding domain
COHLBPCN_02224 1.4e-256
COHLBPCN_02226 5.9e-238
COHLBPCN_02228 4e-17
COHLBPCN_02229 5.7e-55 bldD K domain, Protein
COHLBPCN_02232 0.0
COHLBPCN_02233 1.8e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COHLBPCN_02235 2.6e-230
COHLBPCN_02238 1.8e-175
COHLBPCN_02239 0.0 gp17a S Terminase-like family
COHLBPCN_02240 6.3e-282
COHLBPCN_02241 2.1e-266
COHLBPCN_02242 1.6e-94
COHLBPCN_02243 5.7e-186
COHLBPCN_02244 5.1e-81
COHLBPCN_02245 1.1e-68
COHLBPCN_02247 1.4e-121
COHLBPCN_02248 2.6e-91
COHLBPCN_02249 8.1e-131
COHLBPCN_02250 1.6e-90
COHLBPCN_02253 1e-57
COHLBPCN_02254 1.1e-172
COHLBPCN_02255 8.1e-07
COHLBPCN_02256 2.5e-10 xkdX
COHLBPCN_02257 2.5e-86
COHLBPCN_02258 6.3e-70
COHLBPCN_02259 2.1e-193 xerH A Belongs to the 'phage' integrase family
COHLBPCN_02264 9.3e-116
COHLBPCN_02265 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
COHLBPCN_02266 6.2e-145 S Phage tail protein
COHLBPCN_02267 0.0 S Pfam Transposase IS66
COHLBPCN_02268 6.4e-115
COHLBPCN_02269 0.0 G Exopolysaccharide biosynthesis protein
COHLBPCN_02270 6.5e-164
COHLBPCN_02272 1.6e-186 3.5.1.28 M Ami_2
COHLBPCN_02273 4.4e-32 bhlA S BhlA holin family
COHLBPCN_02274 5.5e-40 S SPP1 phage holin
COHLBPCN_02275 3.4e-74 O protein disulfide oxidoreductase activity
COHLBPCN_02276 4.1e-242 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COHLBPCN_02277 1.2e-70 CO cell redox homeostasis
COHLBPCN_02278 0.0 V Peptidase C39 family
COHLBPCN_02281 1.9e-239 S impB/mucB/samB family C-terminal domain
COHLBPCN_02282 5.8e-55 S YolD-like protein
COHLBPCN_02283 1.3e-37
COHLBPCN_02285 6.8e-09 S Domain of unknown function (DUF4879)
COHLBPCN_02287 2.8e-99 J Acetyltransferase (GNAT) domain
COHLBPCN_02288 3.2e-109 yokK S SMI1 / KNR4 family
COHLBPCN_02289 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
COHLBPCN_02290 1.2e-302 UW nuclease activity
COHLBPCN_02291 6.7e-92 yokH G SMI1 / KNR4 family
COHLBPCN_02292 4.1e-203
COHLBPCN_02293 3.3e-113 yokF 3.1.31.1 L RNA catabolic process
COHLBPCN_02294 1.1e-83 S Bacterial PH domain
COHLBPCN_02295 8.4e-156 aacC 2.3.1.81 V aminoglycoside
COHLBPCN_02298 8.9e-95
COHLBPCN_02299 1.6e-107
COHLBPCN_02300 2.7e-307 yokA L Recombinase
COHLBPCN_02301 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
COHLBPCN_02302 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COHLBPCN_02303 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COHLBPCN_02304 1.6e-70 ypoP K transcriptional
COHLBPCN_02305 2.6e-223 mepA V MATE efflux family protein
COHLBPCN_02306 5.5e-29 ypmT S Uncharacterized ympT
COHLBPCN_02307 5e-99 ypmS S protein conserved in bacteria
COHLBPCN_02308 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
COHLBPCN_02309 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
COHLBPCN_02310 3.1e-40 ypmP S Protein of unknown function (DUF2535)
COHLBPCN_02311 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
COHLBPCN_02312 1.6e-185 pspF K Transcriptional regulator
COHLBPCN_02313 4.2e-110 hlyIII S protein, Hemolysin III
COHLBPCN_02314 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
COHLBPCN_02315 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COHLBPCN_02316 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COHLBPCN_02317 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
COHLBPCN_02318 7.8e-114 ypjP S YpjP-like protein
COHLBPCN_02319 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
COHLBPCN_02320 1.7e-75 yphP S Belongs to the UPF0403 family
COHLBPCN_02321 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
COHLBPCN_02322 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
COHLBPCN_02323 3.1e-110 ypgQ S phosphohydrolase
COHLBPCN_02324 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
COHLBPCN_02325 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
COHLBPCN_02326 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
COHLBPCN_02327 7.9e-31 cspD K Cold-shock protein
COHLBPCN_02328 3.8e-16 degR
COHLBPCN_02329 8.1e-31 S Protein of unknown function (DUF2564)
COHLBPCN_02330 3e-29 ypeQ S Zinc-finger
COHLBPCN_02331 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
COHLBPCN_02332 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
COHLBPCN_02333 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
COHLBPCN_02335 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
COHLBPCN_02336 2e-07
COHLBPCN_02337 1e-38 ypbS S Protein of unknown function (DUF2533)
COHLBPCN_02338 0.0 ypbR S Dynamin family
COHLBPCN_02339 5.1e-87 ypbQ S protein conserved in bacteria
COHLBPCN_02340 4.4e-208 bcsA Q Naringenin-chalcone synthase
COHLBPCN_02341 1.6e-228 pbuX F xanthine
COHLBPCN_02342 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COHLBPCN_02343 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
COHLBPCN_02344 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
COHLBPCN_02345 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
COHLBPCN_02346 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
COHLBPCN_02347 3.9e-187 ptxS K transcriptional
COHLBPCN_02348 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
COHLBPCN_02349 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_02350 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
COHLBPCN_02352 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COHLBPCN_02353 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COHLBPCN_02354 3.3e-92 ypsA S Belongs to the UPF0398 family
COHLBPCN_02355 1.3e-237 yprB L RNase_H superfamily
COHLBPCN_02356 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
COHLBPCN_02357 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
COHLBPCN_02358 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
COHLBPCN_02359 1.2e-48 yppG S YppG-like protein
COHLBPCN_02361 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
COHLBPCN_02364 2.6e-188 yppC S Protein of unknown function (DUF2515)
COHLBPCN_02365 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COHLBPCN_02366 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
COHLBPCN_02367 4.7e-93 ypoC
COHLBPCN_02368 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COHLBPCN_02369 5.7e-129 dnaD L DNA replication protein DnaD
COHLBPCN_02370 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
COHLBPCN_02371 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
COHLBPCN_02372 3.4e-80 ypmB S protein conserved in bacteria
COHLBPCN_02373 6.7e-23 ypmA S Protein of unknown function (DUF4264)
COHLBPCN_02374 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COHLBPCN_02375 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
COHLBPCN_02376 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
COHLBPCN_02377 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
COHLBPCN_02378 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COHLBPCN_02379 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COHLBPCN_02380 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
COHLBPCN_02381 6.9e-130 bshB1 S proteins, LmbE homologs
COHLBPCN_02382 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
COHLBPCN_02383 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COHLBPCN_02384 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
COHLBPCN_02385 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
COHLBPCN_02386 6.1e-143 ypjB S sporulation protein
COHLBPCN_02387 4.4e-98 ypjA S membrane
COHLBPCN_02388 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
COHLBPCN_02389 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
COHLBPCN_02390 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
COHLBPCN_02391 8.5e-78 ypiF S Protein of unknown function (DUF2487)
COHLBPCN_02392 2.8e-99 ypiB S Belongs to the UPF0302 family
COHLBPCN_02393 4.1e-234 S COG0457 FOG TPR repeat
COHLBPCN_02394 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
COHLBPCN_02395 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
COHLBPCN_02396 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COHLBPCN_02397 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
COHLBPCN_02398 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
COHLBPCN_02399 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
COHLBPCN_02400 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
COHLBPCN_02401 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COHLBPCN_02402 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COHLBPCN_02403 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
COHLBPCN_02404 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
COHLBPCN_02405 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
COHLBPCN_02406 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
COHLBPCN_02407 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
COHLBPCN_02408 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COHLBPCN_02409 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COHLBPCN_02410 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
COHLBPCN_02411 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
COHLBPCN_02412 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
COHLBPCN_02413 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COHLBPCN_02414 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
COHLBPCN_02415 5.4e-138 yphF
COHLBPCN_02416 1.6e-18 yphE S Protein of unknown function (DUF2768)
COHLBPCN_02417 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COHLBPCN_02418 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COHLBPCN_02419 1.6e-28 ypzH
COHLBPCN_02420 2.5e-161 seaA S YIEGIA protein
COHLBPCN_02421 1.3e-102 yphA
COHLBPCN_02422 1e-07 S YpzI-like protein
COHLBPCN_02423 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COHLBPCN_02424 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
COHLBPCN_02425 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COHLBPCN_02426 1.8e-23 S Family of unknown function (DUF5359)
COHLBPCN_02427 9.2e-113 ypfA M Flagellar protein YcgR
COHLBPCN_02428 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
COHLBPCN_02429 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
COHLBPCN_02430 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
COHLBPCN_02431 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
COHLBPCN_02432 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
COHLBPCN_02433 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
COHLBPCN_02434 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
COHLBPCN_02435 2.8e-81 ypbF S Protein of unknown function (DUF2663)
COHLBPCN_02436 4.6e-81 ypbE M Lysin motif
COHLBPCN_02437 2.2e-100 ypbD S metal-dependent membrane protease
COHLBPCN_02438 3.2e-286 recQ 3.6.4.12 L DNA helicase
COHLBPCN_02439 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
COHLBPCN_02440 4.7e-41 fer C Ferredoxin
COHLBPCN_02441 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COHLBPCN_02442 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COHLBPCN_02443 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
COHLBPCN_02444 6.8e-201 rsiX
COHLBPCN_02445 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_02446 0.0 resE 2.7.13.3 T Histidine kinase
COHLBPCN_02447 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_02448 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
COHLBPCN_02449 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
COHLBPCN_02450 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
COHLBPCN_02451 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COHLBPCN_02452 1.9e-87 spmB S Spore maturation protein
COHLBPCN_02453 3.5e-103 spmA S Spore maturation protein
COHLBPCN_02454 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
COHLBPCN_02455 4e-98 ypuI S Protein of unknown function (DUF3907)
COHLBPCN_02456 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COHLBPCN_02457 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COHLBPCN_02458 4.5e-94 ypuF S Domain of unknown function (DUF309)
COHLBPCN_02459 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COHLBPCN_02460 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COHLBPCN_02461 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COHLBPCN_02462 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
COHLBPCN_02463 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COHLBPCN_02464 6e-55 ypuD
COHLBPCN_02465 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
COHLBPCN_02466 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
COHLBPCN_02467 1.5e-17 S SNARE associated Golgi protein
COHLBPCN_02470 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COHLBPCN_02471 1.3e-149 ypuA S Secreted protein
COHLBPCN_02472 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COHLBPCN_02473 1.4e-273 spoVAF EG Stage V sporulation protein AF
COHLBPCN_02474 1.4e-110 spoVAEA S stage V sporulation protein
COHLBPCN_02475 2.2e-57 spoVAEB S stage V sporulation protein
COHLBPCN_02476 9e-192 spoVAD I Stage V sporulation protein AD
COHLBPCN_02477 2.3e-78 spoVAC S stage V sporulation protein AC
COHLBPCN_02478 1e-67 spoVAB S Stage V sporulation protein AB
COHLBPCN_02479 7.4e-112 spoVAA S Stage V sporulation protein AA
COHLBPCN_02480 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COHLBPCN_02481 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
COHLBPCN_02482 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
COHLBPCN_02483 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
COHLBPCN_02484 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
COHLBPCN_02485 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
COHLBPCN_02486 2.6e-166 xerD L recombinase XerD
COHLBPCN_02487 3.7e-37 S Protein of unknown function (DUF4227)
COHLBPCN_02488 2.4e-80 fur P Belongs to the Fur family
COHLBPCN_02489 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
COHLBPCN_02490 2e-32 yqkK
COHLBPCN_02491 5.5e-242 mleA 1.1.1.38 C malic enzyme
COHLBPCN_02492 3.1e-235 mleN C Na H antiporter
COHLBPCN_02493 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
COHLBPCN_02494 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
COHLBPCN_02495 4.5e-58 ansR K Transcriptional regulator
COHLBPCN_02496 3e-223 yqxK 3.6.4.12 L DNA helicase
COHLBPCN_02497 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
COHLBPCN_02499 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
COHLBPCN_02500 4e-14 yqkE S Protein of unknown function (DUF3886)
COHLBPCN_02501 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
COHLBPCN_02502 9.4e-39 yqkC S Protein of unknown function (DUF2552)
COHLBPCN_02503 2.8e-54 yqkB S Belongs to the HesB IscA family
COHLBPCN_02504 4.7e-196 yqkA K GrpB protein
COHLBPCN_02505 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
COHLBPCN_02506 3.6e-87 yqjY K acetyltransferase
COHLBPCN_02507 2.2e-49 S YolD-like protein
COHLBPCN_02508 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COHLBPCN_02510 5.2e-226 yqjV G Major Facilitator Superfamily
COHLBPCN_02512 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COHLBPCN_02513 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
COHLBPCN_02514 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
COHLBPCN_02515 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_02516 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
COHLBPCN_02517 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COHLBPCN_02518 0.0 rocB E arginine degradation protein
COHLBPCN_02519 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
COHLBPCN_02520 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COHLBPCN_02521 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COHLBPCN_02522 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COHLBPCN_02523 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COHLBPCN_02524 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COHLBPCN_02525 4.5e-24 yqzJ
COHLBPCN_02526 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COHLBPCN_02527 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
COHLBPCN_02528 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
COHLBPCN_02529 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
COHLBPCN_02530 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
COHLBPCN_02532 1.4e-98 yqjB S protein conserved in bacteria
COHLBPCN_02533 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
COHLBPCN_02534 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
COHLBPCN_02535 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
COHLBPCN_02536 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
COHLBPCN_02537 9.3e-77 yqiW S Belongs to the UPF0403 family
COHLBPCN_02538 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
COHLBPCN_02539 7.9e-208 norA EGP Major facilitator Superfamily
COHLBPCN_02540 2.6e-152 bmrR K helix_turn_helix, mercury resistance
COHLBPCN_02541 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COHLBPCN_02542 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
COHLBPCN_02543 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
COHLBPCN_02544 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
COHLBPCN_02545 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
COHLBPCN_02546 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
COHLBPCN_02547 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
COHLBPCN_02548 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
COHLBPCN_02549 4e-34 yqzF S Protein of unknown function (DUF2627)
COHLBPCN_02550 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
COHLBPCN_02551 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
COHLBPCN_02552 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
COHLBPCN_02553 1.8e-212 mmgC I acyl-CoA dehydrogenase
COHLBPCN_02554 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
COHLBPCN_02555 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
COHLBPCN_02556 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COHLBPCN_02557 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
COHLBPCN_02558 5.9e-27
COHLBPCN_02559 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
COHLBPCN_02561 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
COHLBPCN_02562 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
COHLBPCN_02563 0.0 recN L May be involved in recombinational repair of damaged DNA
COHLBPCN_02564 1.7e-78 argR K Regulates arginine biosynthesis genes
COHLBPCN_02565 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
COHLBPCN_02566 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COHLBPCN_02567 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COHLBPCN_02568 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COHLBPCN_02569 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COHLBPCN_02570 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COHLBPCN_02571 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COHLBPCN_02572 2.1e-67 yqhY S protein conserved in bacteria
COHLBPCN_02573 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
COHLBPCN_02574 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COHLBPCN_02575 9.9e-91 spoIIIAH S SpoIIIAH-like protein
COHLBPCN_02576 6.9e-103 spoIIIAG S stage III sporulation protein AG
COHLBPCN_02577 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
COHLBPCN_02578 1.3e-197 spoIIIAE S stage III sporulation protein AE
COHLBPCN_02579 2.3e-58 spoIIIAD S Stage III sporulation protein AD
COHLBPCN_02580 7.6e-29 spoIIIAC S stage III sporulation protein AC
COHLBPCN_02581 2.9e-85 spoIIIAB S Stage III sporulation protein
COHLBPCN_02582 1.2e-171 spoIIIAA S stage III sporulation protein AA
COHLBPCN_02583 7.9e-37 yqhV S Protein of unknown function (DUF2619)
COHLBPCN_02584 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COHLBPCN_02585 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
COHLBPCN_02586 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
COHLBPCN_02587 2.3e-93 yqhR S Conserved membrane protein YqhR
COHLBPCN_02588 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
COHLBPCN_02589 2.2e-61 yqhP
COHLBPCN_02590 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
COHLBPCN_02591 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
COHLBPCN_02592 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
COHLBPCN_02593 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
COHLBPCN_02594 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
COHLBPCN_02595 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
COHLBPCN_02596 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
COHLBPCN_02597 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
COHLBPCN_02598 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
COHLBPCN_02599 1.2e-24 sinI S Anti-repressor SinI
COHLBPCN_02600 1e-54 sinR K transcriptional
COHLBPCN_02601 2.3e-142 tasA S Cell division protein FtsN
COHLBPCN_02602 6.7e-59 sipW 3.4.21.89 U Signal peptidase
COHLBPCN_02603 2.1e-116 yqxM
COHLBPCN_02604 7.3e-54 yqzG S Protein of unknown function (DUF3889)
COHLBPCN_02605 1.4e-26 yqzE S YqzE-like protein
COHLBPCN_02606 3.7e-42 S ComG operon protein 7
COHLBPCN_02607 5.5e-49 comGF U Putative Competence protein ComGF
COHLBPCN_02608 1.1e-59 comGE
COHLBPCN_02609 4.4e-71 gspH NU protein transport across the cell outer membrane
COHLBPCN_02610 1.4e-47 comGC U Required for transformation and DNA binding
COHLBPCN_02611 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
COHLBPCN_02612 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
COHLBPCN_02614 7.2e-175 corA P Mg2 transporter protein
COHLBPCN_02615 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
COHLBPCN_02616 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COHLBPCN_02618 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
COHLBPCN_02619 1.8e-37 yqgY S Protein of unknown function (DUF2626)
COHLBPCN_02620 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
COHLBPCN_02621 8.9e-23 yqgW S Protein of unknown function (DUF2759)
COHLBPCN_02622 6.9e-50 yqgV S Thiamine-binding protein
COHLBPCN_02623 2.7e-199 yqgU
COHLBPCN_02624 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
COHLBPCN_02625 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
COHLBPCN_02626 5.2e-181 glcK 2.7.1.2 G Glucokinase
COHLBPCN_02627 3.1e-33 yqgQ S Protein conserved in bacteria
COHLBPCN_02628 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
COHLBPCN_02629 2.5e-09 yqgO
COHLBPCN_02630 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COHLBPCN_02631 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COHLBPCN_02632 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
COHLBPCN_02634 9.2e-51 yqzD
COHLBPCN_02635 1.9e-75 yqzC S YceG-like family
COHLBPCN_02636 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COHLBPCN_02637 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COHLBPCN_02638 4.4e-158 pstA P Phosphate transport system permease
COHLBPCN_02639 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
COHLBPCN_02640 5.3e-151 pstS P Phosphate
COHLBPCN_02641 0.0 pbpA 3.4.16.4 M penicillin-binding protein
COHLBPCN_02642 2.5e-231 yqgE EGP Major facilitator superfamily
COHLBPCN_02643 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
COHLBPCN_02644 4e-73 yqgC S protein conserved in bacteria
COHLBPCN_02645 8.5e-134 yqgB S Protein of unknown function (DUF1189)
COHLBPCN_02646 2.2e-75 yqgA
COHLBPCN_02647 5.2e-47 yqfZ M LysM domain
COHLBPCN_02648 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
COHLBPCN_02649 4.3e-62 yqfX S membrane
COHLBPCN_02650 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
COHLBPCN_02651 1.9e-77 zur P Belongs to the Fur family
COHLBPCN_02652 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
COHLBPCN_02653 2.1e-36 yqfT S Protein of unknown function (DUF2624)
COHLBPCN_02654 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
COHLBPCN_02655 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COHLBPCN_02656 2.9e-14 yqfQ S YqfQ-like protein
COHLBPCN_02657 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
COHLBPCN_02658 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COHLBPCN_02659 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
COHLBPCN_02660 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
COHLBPCN_02661 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COHLBPCN_02662 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COHLBPCN_02663 4.5e-88 yaiI S Belongs to the UPF0178 family
COHLBPCN_02664 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COHLBPCN_02665 4.5e-112 ccpN K CBS domain
COHLBPCN_02666 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COHLBPCN_02667 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COHLBPCN_02668 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
COHLBPCN_02669 8.4e-19 S YqzL-like protein
COHLBPCN_02670 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COHLBPCN_02671 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
COHLBPCN_02672 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
COHLBPCN_02673 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COHLBPCN_02674 0.0 yqfF S membrane-associated HD superfamily hydrolase
COHLBPCN_02676 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
COHLBPCN_02677 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
COHLBPCN_02678 2.7e-45 yqfC S sporulation protein YqfC
COHLBPCN_02679 6e-25 yqfB
COHLBPCN_02680 4.3e-122 yqfA S UPF0365 protein
COHLBPCN_02681 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
COHLBPCN_02682 2.5e-61 yqeY S Yqey-like protein
COHLBPCN_02683 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COHLBPCN_02684 1.6e-158 yqeW P COG1283 Na phosphate symporter
COHLBPCN_02685 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
COHLBPCN_02686 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COHLBPCN_02687 5.4e-175 prmA J Methylates ribosomal protein L11
COHLBPCN_02688 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COHLBPCN_02689 0.0 dnaK O Heat shock 70 kDa protein
COHLBPCN_02690 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COHLBPCN_02691 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COHLBPCN_02692 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
COHLBPCN_02693 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COHLBPCN_02694 1e-54 yqxA S Protein of unknown function (DUF3679)
COHLBPCN_02695 6.9e-223 spoIIP M stage II sporulation protein P
COHLBPCN_02696 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
COHLBPCN_02697 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
COHLBPCN_02698 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
COHLBPCN_02699 4.1e-15 S YqzM-like protein
COHLBPCN_02700 0.0 comEC S Competence protein ComEC
COHLBPCN_02701 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
COHLBPCN_02702 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
COHLBPCN_02703 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COHLBPCN_02704 2.9e-139 yqeM Q Methyltransferase
COHLBPCN_02705 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COHLBPCN_02706 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
COHLBPCN_02707 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COHLBPCN_02708 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
COHLBPCN_02709 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COHLBPCN_02710 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
COHLBPCN_02711 5.3e-95 yqeG S hydrolase of the HAD superfamily
COHLBPCN_02713 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
COHLBPCN_02714 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COHLBPCN_02715 4.7e-106 yqeD S SNARE associated Golgi protein
COHLBPCN_02716 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
COHLBPCN_02717 2.3e-133 yqeB
COHLBPCN_02718 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
COHLBPCN_02719 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COHLBPCN_02720 1.4e-281 cisA2 L Recombinase
COHLBPCN_02721 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
COHLBPCN_02722 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
COHLBPCN_02723 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COHLBPCN_02724 1.6e-54 arsR K ArsR family transcriptional regulator
COHLBPCN_02725 1.1e-152 yqcI S YqcI/YcgG family
COHLBPCN_02726 1.6e-96 S Tetratricopeptide repeat
COHLBPCN_02729 3.8e-277 A Pre-toxin TG
COHLBPCN_02730 1.1e-104 S Suppressor of fused protein (SUFU)
COHLBPCN_02732 5e-60
COHLBPCN_02734 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
COHLBPCN_02735 2.6e-68 S Bacteriophage holin family
COHLBPCN_02736 4.8e-165 xepA
COHLBPCN_02737 1.3e-23
COHLBPCN_02738 4.1e-56 xkdW S XkdW protein
COHLBPCN_02739 2e-221
COHLBPCN_02740 9.6e-40
COHLBPCN_02741 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
COHLBPCN_02742 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
COHLBPCN_02743 9.6e-71 xkdS S Protein of unknown function (DUF2634)
COHLBPCN_02744 1.8e-38 xkdR S Protein of unknown function (DUF2577)
COHLBPCN_02745 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
COHLBPCN_02746 9e-114 xkdP S Lysin motif
COHLBPCN_02747 0.0 xkdO L Transglycosylase SLT domain
COHLBPCN_02748 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
COHLBPCN_02750 3.6e-76 xkdM S Phage tail tube protein
COHLBPCN_02751 5.5e-256 xkdK S Phage tail sheath C-terminal domain
COHLBPCN_02752 3.2e-26
COHLBPCN_02753 1.4e-77
COHLBPCN_02754 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
COHLBPCN_02755 6.7e-65 yqbH S Domain of unknown function (DUF3599)
COHLBPCN_02756 2.1e-67 S Protein of unknown function (DUF3199)
COHLBPCN_02757 3.6e-51 S YqbF, hypothetical protein domain
COHLBPCN_02758 1.9e-167 xkdG S Phage capsid family
COHLBPCN_02759 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
COHLBPCN_02760 2e-115
COHLBPCN_02761 5.7e-169 S Phage Mu protein F like protein
COHLBPCN_02762 5.9e-296 yqbA S portal protein
COHLBPCN_02763 2.4e-253 S phage terminase, large subunit
COHLBPCN_02764 6.3e-107 yqaS L DNA packaging
COHLBPCN_02766 6.5e-81 L Transposase
COHLBPCN_02767 1.6e-166
COHLBPCN_02768 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
COHLBPCN_02769 7.2e-74 rusA L Endodeoxyribonuclease RusA
COHLBPCN_02771 5.9e-168 xkdC L IstB-like ATP binding protein
COHLBPCN_02772 4.7e-123 3.1.3.16 L DnaD domain protein
COHLBPCN_02773 2.5e-155 recT L RecT family
COHLBPCN_02774 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
COHLBPCN_02778 1.2e-103
COHLBPCN_02780 6.5e-37 K Helix-turn-helix XRE-family like proteins
COHLBPCN_02781 1.1e-56 K sequence-specific DNA binding
COHLBPCN_02783 1e-101 adk 2.7.4.3 F adenylate kinase activity
COHLBPCN_02784 1.4e-100 yqaB E IrrE N-terminal-like domain
COHLBPCN_02785 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COHLBPCN_02786 2e-68 psiE S Protein PsiE homolog
COHLBPCN_02787 9e-237 yrkQ T Histidine kinase
COHLBPCN_02788 1.1e-127 T Transcriptional regulator
COHLBPCN_02789 8.2e-224 yrkO P Protein of unknown function (DUF418)
COHLBPCN_02790 6e-105 yrkN K Acetyltransferase (GNAT) family
COHLBPCN_02791 1.5e-97 ywrO S Flavodoxin-like fold
COHLBPCN_02792 2.8e-79 S Protein of unknown function with HXXEE motif
COHLBPCN_02793 4.3e-117 yrkJ S membrane transporter protein
COHLBPCN_02794 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
COHLBPCN_02795 2.3e-212 yrkH P Rhodanese Homology Domain
COHLBPCN_02796 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
COHLBPCN_02797 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
COHLBPCN_02798 7.8e-39 yrkD S protein conserved in bacteria
COHLBPCN_02799 2.6e-108 yrkC G Cupin domain
COHLBPCN_02800 4.8e-151 bltR K helix_turn_helix, mercury resistance
COHLBPCN_02801 3.5e-211 blt EGP Major facilitator Superfamily
COHLBPCN_02802 1.4e-83 bltD 2.3.1.57 K FR47-like protein
COHLBPCN_02803 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
COHLBPCN_02804 2.1e-17 S YrzO-like protein
COHLBPCN_02805 1.7e-171 yrdR EG EamA-like transporter family
COHLBPCN_02806 5.9e-160 yrdQ K Transcriptional regulator
COHLBPCN_02807 2e-199 trkA P Oxidoreductase
COHLBPCN_02808 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
COHLBPCN_02809 1.3e-66 yodA S tautomerase
COHLBPCN_02810 7.7e-163 gltR K LysR substrate binding domain
COHLBPCN_02812 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
COHLBPCN_02813 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
COHLBPCN_02814 3.3e-138 azlC E AzlC protein
COHLBPCN_02815 2.2e-79 bkdR K helix_turn_helix ASNC type
COHLBPCN_02816 4.1e-46 yrdF K ribonuclease inhibitor
COHLBPCN_02817 4.1e-231 cypA C Cytochrome P450
COHLBPCN_02818 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
COHLBPCN_02819 1.9e-57 S Protein of unknown function (DUF2568)
COHLBPCN_02820 1.2e-91 yrdA S DinB family
COHLBPCN_02821 7.6e-168 aadK G Streptomycin adenylyltransferase
COHLBPCN_02822 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
COHLBPCN_02823 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COHLBPCN_02824 3e-125 yrpD S Domain of unknown function, YrpD
COHLBPCN_02826 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
COHLBPCN_02827 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_02828 4.5e-188 yrpG C Aldo/keto reductase family
COHLBPCN_02829 9.5e-226 yraO C Citrate transporter
COHLBPCN_02830 1.2e-163 yraN K Transcriptional regulator
COHLBPCN_02831 2.4e-206 yraM S PrpF protein
COHLBPCN_02833 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
COHLBPCN_02834 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COHLBPCN_02835 3.2e-155 S Alpha beta hydrolase
COHLBPCN_02836 1.7e-60 T sh3 domain protein
COHLBPCN_02837 2.4e-61 T sh3 domain protein
COHLBPCN_02838 1.3e-66 E Glyoxalase-like domain
COHLBPCN_02839 5.3e-37 yraG
COHLBPCN_02840 6.4e-63 yraF M Spore coat protein
COHLBPCN_02841 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
COHLBPCN_02842 2.6e-26 yraE
COHLBPCN_02843 1.1e-49 yraD M Spore coat protein
COHLBPCN_02844 4.3e-47 yraB K helix_turn_helix, mercury resistance
COHLBPCN_02845 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
COHLBPCN_02846 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
COHLBPCN_02847 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
COHLBPCN_02848 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
COHLBPCN_02849 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
COHLBPCN_02850 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
COHLBPCN_02851 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
COHLBPCN_02852 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
COHLBPCN_02853 0.0 levR K PTS system fructose IIA component
COHLBPCN_02854 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
COHLBPCN_02855 3.6e-106 yrhP E LysE type translocator
COHLBPCN_02856 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
COHLBPCN_02857 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_02858 1.7e-151 rsiV S Protein of unknown function (DUF3298)
COHLBPCN_02859 0.0 yrhL I Acyltransferase family
COHLBPCN_02860 1.5e-46 yrhK S YrhK-like protein
COHLBPCN_02861 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
COHLBPCN_02862 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
COHLBPCN_02863 4.5e-97 yrhH Q methyltransferase
COHLBPCN_02866 1.8e-142 focA P Formate nitrite
COHLBPCN_02867 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
COHLBPCN_02868 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
COHLBPCN_02869 1.4e-78 yrhD S Protein of unknown function (DUF1641)
COHLBPCN_02870 4.6e-35 yrhC S YrhC-like protein
COHLBPCN_02871 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COHLBPCN_02872 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
COHLBPCN_02873 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COHLBPCN_02874 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
COHLBPCN_02875 7e-27 yrzA S Protein of unknown function (DUF2536)
COHLBPCN_02876 4.2e-63 yrrS S Protein of unknown function (DUF1510)
COHLBPCN_02877 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
COHLBPCN_02878 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COHLBPCN_02879 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
COHLBPCN_02880 2.7e-246 yegQ O COG0826 Collagenase and related proteases
COHLBPCN_02881 7.8e-174 yegQ O Peptidase U32
COHLBPCN_02882 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
COHLBPCN_02883 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COHLBPCN_02884 1.2e-45 yrzB S Belongs to the UPF0473 family
COHLBPCN_02885 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COHLBPCN_02886 1.7e-41 yrzL S Belongs to the UPF0297 family
COHLBPCN_02887 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COHLBPCN_02888 2.7e-170 yrrI S AI-2E family transporter
COHLBPCN_02889 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
COHLBPCN_02890 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
COHLBPCN_02891 3.6e-109 gluC P ABC transporter
COHLBPCN_02892 7.6e-107 glnP P ABC transporter
COHLBPCN_02893 8e-08 S Protein of unknown function (DUF3918)
COHLBPCN_02894 9.8e-31 yrzR
COHLBPCN_02895 1.8e-83 yrrD S protein conserved in bacteria
COHLBPCN_02896 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COHLBPCN_02897 1.4e-15 S COG0457 FOG TPR repeat
COHLBPCN_02898 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COHLBPCN_02899 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
COHLBPCN_02900 1.2e-70 cymR K Transcriptional regulator
COHLBPCN_02901 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
COHLBPCN_02902 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
COHLBPCN_02903 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
COHLBPCN_02904 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
COHLBPCN_02906 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
COHLBPCN_02907 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COHLBPCN_02908 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COHLBPCN_02909 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COHLBPCN_02910 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COHLBPCN_02911 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
COHLBPCN_02912 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
COHLBPCN_02913 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
COHLBPCN_02914 9.4e-49 yrzD S Post-transcriptional regulator
COHLBPCN_02915 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COHLBPCN_02916 2.2e-114 yrbG S membrane
COHLBPCN_02917 1.2e-74 yrzE S Protein of unknown function (DUF3792)
COHLBPCN_02918 1.1e-38 yajC U Preprotein translocase subunit YajC
COHLBPCN_02919 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COHLBPCN_02920 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
COHLBPCN_02921 2.6e-18 yrzS S Protein of unknown function (DUF2905)
COHLBPCN_02922 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COHLBPCN_02923 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COHLBPCN_02924 4.8e-93 bofC S BofC C-terminal domain
COHLBPCN_02925 5.3e-253 csbX EGP Major facilitator Superfamily
COHLBPCN_02926 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
COHLBPCN_02927 6.5e-119 yrzF T serine threonine protein kinase
COHLBPCN_02929 2.6e-35 S Family of unknown function (DUF5412)
COHLBPCN_02930 1.8e-262 alsT E Sodium alanine symporter
COHLBPCN_02931 1.9e-127 yebC K transcriptional regulatory protein
COHLBPCN_02932 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
COHLBPCN_02933 9.8e-158 safA M spore coat assembly protein SafA
COHLBPCN_02934 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
COHLBPCN_02935 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
COHLBPCN_02936 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
COHLBPCN_02937 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
COHLBPCN_02938 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
COHLBPCN_02939 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
COHLBPCN_02940 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
COHLBPCN_02941 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COHLBPCN_02942 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
COHLBPCN_02943 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COHLBPCN_02944 4.1e-56 ysxB J ribosomal protein
COHLBPCN_02945 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
COHLBPCN_02946 9.2e-161 spoIVFB S Stage IV sporulation protein
COHLBPCN_02947 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
COHLBPCN_02948 2.5e-144 minD D Belongs to the ParA family
COHLBPCN_02949 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
COHLBPCN_02950 1.4e-84 mreD M shape-determining protein
COHLBPCN_02951 2.8e-157 mreC M Involved in formation and maintenance of cell shape
COHLBPCN_02952 1.8e-184 mreB D Rod shape-determining protein MreB
COHLBPCN_02953 5.9e-126 radC E Belongs to the UPF0758 family
COHLBPCN_02954 2.8e-102 maf D septum formation protein Maf
COHLBPCN_02955 1.1e-168 spoIIB S Sporulation related domain
COHLBPCN_02956 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
COHLBPCN_02957 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COHLBPCN_02958 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COHLBPCN_02959 1.6e-25
COHLBPCN_02960 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
COHLBPCN_02961 1.9e-226 spoVID M stage VI sporulation protein D
COHLBPCN_02962 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
COHLBPCN_02963 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
COHLBPCN_02964 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
COHLBPCN_02965 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
COHLBPCN_02966 3.6e-146 hemX O cytochrome C
COHLBPCN_02967 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
COHLBPCN_02968 1.4e-89 ysxD
COHLBPCN_02969 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
COHLBPCN_02970 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
COHLBPCN_02971 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
COHLBPCN_02972 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COHLBPCN_02973 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COHLBPCN_02974 2.3e-187 ysoA H Tetratricopeptide repeat
COHLBPCN_02975 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COHLBPCN_02976 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COHLBPCN_02977 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
COHLBPCN_02978 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
COHLBPCN_02979 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
COHLBPCN_02980 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
COHLBPCN_02981 0.0 ilvB 2.2.1.6 E Acetolactate synthase
COHLBPCN_02983 7.6e-82 ysnE K acetyltransferase
COHLBPCN_02984 9.1e-134 ysnF S protein conserved in bacteria
COHLBPCN_02986 1.4e-92 ysnB S Phosphoesterase
COHLBPCN_02987 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COHLBPCN_02988 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
COHLBPCN_02989 2.9e-196 gerM S COG5401 Spore germination protein
COHLBPCN_02990 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COHLBPCN_02991 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_02992 3.3e-30 gerE K Transcriptional regulator
COHLBPCN_02993 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
COHLBPCN_02994 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
COHLBPCN_02995 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
COHLBPCN_02996 2.4e-107 sdhC C succinate dehydrogenase
COHLBPCN_02997 1.2e-79 yslB S Protein of unknown function (DUF2507)
COHLBPCN_02998 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
COHLBPCN_02999 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COHLBPCN_03000 2e-52 trxA O Belongs to the thioredoxin family
COHLBPCN_03001 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
COHLBPCN_03003 4.2e-178 etfA C Electron transfer flavoprotein
COHLBPCN_03004 1.2e-135 etfB C Electron transfer flavoprotein
COHLBPCN_03005 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
COHLBPCN_03006 2.7e-100 fadR K Transcriptional regulator
COHLBPCN_03007 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COHLBPCN_03008 7.3e-68 yshE S membrane
COHLBPCN_03009 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COHLBPCN_03010 0.0 polX L COG1796 DNA polymerase IV (family X)
COHLBPCN_03011 1.3e-85 cvpA S membrane protein, required for colicin V production
COHLBPCN_03012 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
COHLBPCN_03013 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COHLBPCN_03014 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COHLBPCN_03015 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COHLBPCN_03016 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COHLBPCN_03017 2.6e-32 sspI S Belongs to the SspI family
COHLBPCN_03018 4.4e-208 ysfB KT regulator
COHLBPCN_03019 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
COHLBPCN_03020 5.6e-258 glcF C Glycolate oxidase
COHLBPCN_03021 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
COHLBPCN_03023 0.0 cstA T Carbon starvation protein
COHLBPCN_03024 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
COHLBPCN_03025 3.4e-144 araQ G transport system permease
COHLBPCN_03026 1.4e-167 araP G carbohydrate transport
COHLBPCN_03027 2.8e-254 araN G carbohydrate transport
COHLBPCN_03028 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
COHLBPCN_03029 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
COHLBPCN_03030 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
COHLBPCN_03031 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
COHLBPCN_03032 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
COHLBPCN_03033 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
COHLBPCN_03034 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
COHLBPCN_03035 9.2e-68 ysdB S Sigma-w pathway protein YsdB
COHLBPCN_03036 7.5e-45 ysdA S Membrane
COHLBPCN_03037 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COHLBPCN_03038 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COHLBPCN_03039 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COHLBPCN_03041 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
COHLBPCN_03042 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
COHLBPCN_03043 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
COHLBPCN_03044 0.0 lytS 2.7.13.3 T Histidine kinase
COHLBPCN_03045 1.5e-149 ysaA S HAD-hyrolase-like
COHLBPCN_03046 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COHLBPCN_03047 3.8e-159 ytxC S YtxC-like family
COHLBPCN_03048 4.9e-111 ytxB S SNARE associated Golgi protein
COHLBPCN_03049 3e-173 dnaI L Primosomal protein DnaI
COHLBPCN_03050 3.5e-266 dnaB L Membrane attachment protein
COHLBPCN_03051 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COHLBPCN_03052 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
COHLBPCN_03053 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COHLBPCN_03054 9.9e-67 ytcD K Transcriptional regulator
COHLBPCN_03055 4.9e-205 ytbD EGP Major facilitator Superfamily
COHLBPCN_03056 8.9e-161 ytbE S reductase
COHLBPCN_03057 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COHLBPCN_03058 1.1e-107 ytaF P Probably functions as a manganese efflux pump
COHLBPCN_03059 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COHLBPCN_03060 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COHLBPCN_03061 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
COHLBPCN_03062 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_03063 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
COHLBPCN_03064 1.8e-242 icd 1.1.1.42 C isocitrate
COHLBPCN_03065 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
COHLBPCN_03066 4.7e-71 yeaL S membrane
COHLBPCN_03067 2.6e-192 ytvI S sporulation integral membrane protein YtvI
COHLBPCN_03068 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
COHLBPCN_03069 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COHLBPCN_03070 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COHLBPCN_03071 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
COHLBPCN_03072 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COHLBPCN_03073 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
COHLBPCN_03074 0.0 dnaE 2.7.7.7 L DNA polymerase
COHLBPCN_03075 3.2e-56 ytrH S Sporulation protein YtrH
COHLBPCN_03076 8.2e-69 ytrI
COHLBPCN_03077 9.2e-29
COHLBPCN_03078 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
COHLBPCN_03079 2.4e-47 ytpI S YtpI-like protein
COHLBPCN_03080 8e-241 ytoI K transcriptional regulator containing CBS domains
COHLBPCN_03081 1.2e-158 ytnM S membrane transporter protein
COHLBPCN_03082 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
COHLBPCN_03083 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
COHLBPCN_03084 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COHLBPCN_03085 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
COHLBPCN_03086 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COHLBPCN_03087 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
COHLBPCN_03088 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
COHLBPCN_03089 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
COHLBPCN_03090 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
COHLBPCN_03091 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
COHLBPCN_03092 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
COHLBPCN_03093 2.9e-173 ytlI K LysR substrate binding domain
COHLBPCN_03094 1.7e-130 ytkL S Belongs to the UPF0173 family
COHLBPCN_03095 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_03097 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
COHLBPCN_03098 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
COHLBPCN_03099 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
COHLBPCN_03100 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COHLBPCN_03101 7e-165 ytxK 2.1.1.72 L DNA methylase
COHLBPCN_03102 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COHLBPCN_03103 8.7e-70 ytfJ S Sporulation protein YtfJ
COHLBPCN_03104 5.6e-116 ytfI S Protein of unknown function (DUF2953)
COHLBPCN_03105 1.3e-87 yteJ S RDD family
COHLBPCN_03106 2.4e-181 sppA OU signal peptide peptidase SppA
COHLBPCN_03107 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COHLBPCN_03108 0.0 ytcJ S amidohydrolase
COHLBPCN_03109 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
COHLBPCN_03110 2e-29 sspB S spore protein
COHLBPCN_03111 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COHLBPCN_03112 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
COHLBPCN_03113 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
COHLBPCN_03114 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COHLBPCN_03115 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
COHLBPCN_03116 3.4e-109 yttP K Transcriptional regulator
COHLBPCN_03117 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
COHLBPCN_03118 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
COHLBPCN_03119 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COHLBPCN_03121 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COHLBPCN_03122 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
COHLBPCN_03123 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
COHLBPCN_03124 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
COHLBPCN_03125 1.9e-225 acuC BQ histone deacetylase
COHLBPCN_03126 1.4e-125 motS N Flagellar motor protein
COHLBPCN_03127 7.1e-147 motA N flagellar motor
COHLBPCN_03128 1.7e-182 ccpA K catabolite control protein A
COHLBPCN_03129 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
COHLBPCN_03130 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
COHLBPCN_03131 6.6e-17 ytxH S COG4980 Gas vesicle protein
COHLBPCN_03132 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COHLBPCN_03133 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COHLBPCN_03134 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
COHLBPCN_03135 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COHLBPCN_03136 9.8e-149 ytpQ S Belongs to the UPF0354 family
COHLBPCN_03137 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COHLBPCN_03138 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
COHLBPCN_03139 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
COHLBPCN_03140 9.8e-52 ytzB S small secreted protein
COHLBPCN_03141 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
COHLBPCN_03142 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
COHLBPCN_03143 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COHLBPCN_03144 2e-45 ytzH S YtzH-like protein
COHLBPCN_03145 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
COHLBPCN_03146 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
COHLBPCN_03147 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
COHLBPCN_03148 1.3e-165 ytlQ
COHLBPCN_03149 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
COHLBPCN_03150 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COHLBPCN_03151 7.1e-272 pepV 3.5.1.18 E Dipeptidase
COHLBPCN_03152 7.2e-226 pbuO S permease
COHLBPCN_03153 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
COHLBPCN_03154 4.3e-132 ythP V ABC transporter
COHLBPCN_03155 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
COHLBPCN_03156 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COHLBPCN_03157 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COHLBPCN_03158 8.2e-232 ytfP S HI0933-like protein
COHLBPCN_03159 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
COHLBPCN_03160 3.1e-26 yteV S Sporulation protein Cse60
COHLBPCN_03161 4.8e-117 yteU S Integral membrane protein
COHLBPCN_03162 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
COHLBPCN_03163 4.6e-73 yteS G transport
COHLBPCN_03164 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
COHLBPCN_03165 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
COHLBPCN_03166 0.0 ytdP K Transcriptional regulator
COHLBPCN_03167 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
COHLBPCN_03168 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
COHLBPCN_03169 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
COHLBPCN_03170 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
COHLBPCN_03171 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
COHLBPCN_03172 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
COHLBPCN_03173 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
COHLBPCN_03174 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
COHLBPCN_03175 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
COHLBPCN_03176 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
COHLBPCN_03177 2.3e-190 msmR K Transcriptional regulator
COHLBPCN_03178 2.3e-248 msmE G Bacterial extracellular solute-binding protein
COHLBPCN_03179 3.7e-168 amyD P ABC transporter
COHLBPCN_03180 1.5e-144 amyC P ABC transporter (permease)
COHLBPCN_03181 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
COHLBPCN_03182 2.1e-51 ytwF P Sulfurtransferase
COHLBPCN_03183 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COHLBPCN_03184 7.7e-55 ytvB S Protein of unknown function (DUF4257)
COHLBPCN_03185 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
COHLBPCN_03186 2.1e-211 yttB EGP Major facilitator Superfamily
COHLBPCN_03187 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
COHLBPCN_03188 0.0 bceB V ABC transporter (permease)
COHLBPCN_03189 1.1e-138 bceA V ABC transporter, ATP-binding protein
COHLBPCN_03190 5.6e-186 T PhoQ Sensor
COHLBPCN_03191 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_03192 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
COHLBPCN_03193 3.1e-127 ytrE V ABC transporter, ATP-binding protein
COHLBPCN_03194 5.9e-148
COHLBPCN_03195 6.1e-169 P ABC-2 family transporter protein
COHLBPCN_03196 1.1e-161 ytrB P abc transporter atp-binding protein
COHLBPCN_03197 5.1e-66 ytrA K GntR family transcriptional regulator
COHLBPCN_03199 6.7e-41 ytzC S Protein of unknown function (DUF2524)
COHLBPCN_03200 2.1e-190 yhcC S Fe-S oxidoreductase
COHLBPCN_03201 3.3e-106 ytqB J Putative rRNA methylase
COHLBPCN_03202 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
COHLBPCN_03203 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
COHLBPCN_03204 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
COHLBPCN_03205 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
COHLBPCN_03206 0.0 asnB 6.3.5.4 E Asparagine synthase
COHLBPCN_03207 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COHLBPCN_03208 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
COHLBPCN_03209 1.2e-38 ytmB S Protein of unknown function (DUF2584)
COHLBPCN_03210 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
COHLBPCN_03211 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
COHLBPCN_03212 1.4e-144 ytlC P ABC transporter
COHLBPCN_03213 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
COHLBPCN_03214 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
COHLBPCN_03215 5.4e-63 ytkC S Bacteriophage holin family
COHLBPCN_03216 2.1e-76 dps P Belongs to the Dps family
COHLBPCN_03218 3.6e-73 ytkA S YtkA-like
COHLBPCN_03219 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COHLBPCN_03220 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
COHLBPCN_03221 3.6e-41 rpmE2 J Ribosomal protein L31
COHLBPCN_03222 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
COHLBPCN_03223 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
COHLBPCN_03224 1.1e-24 S Domain of Unknown Function (DUF1540)
COHLBPCN_03225 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
COHLBPCN_03226 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
COHLBPCN_03227 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
COHLBPCN_03228 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
COHLBPCN_03229 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
COHLBPCN_03230 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
COHLBPCN_03231 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COHLBPCN_03232 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
COHLBPCN_03233 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
COHLBPCN_03234 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
COHLBPCN_03235 2.6e-132 dksA T COG1734 DnaK suppressor protein
COHLBPCN_03236 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
COHLBPCN_03237 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COHLBPCN_03238 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
COHLBPCN_03239 3.6e-235 ytcC M Glycosyltransferase Family 4
COHLBPCN_03241 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
COHLBPCN_03242 1.8e-217 cotSA M Glycosyl transferases group 1
COHLBPCN_03243 1.8e-206 cotI S Spore coat protein
COHLBPCN_03244 9.9e-77 tspO T membrane
COHLBPCN_03245 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COHLBPCN_03246 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
COHLBPCN_03247 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
COHLBPCN_03248 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COHLBPCN_03249 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COHLBPCN_03258 7.8e-08
COHLBPCN_03259 1.3e-09
COHLBPCN_03266 2e-08
COHLBPCN_03271 3.4e-39 S COG NOG14552 non supervised orthologous group
COHLBPCN_03272 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
COHLBPCN_03273 3.4e-94 M1-753 M FR47-like protein
COHLBPCN_03274 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
COHLBPCN_03275 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
COHLBPCN_03276 3.9e-84 yuaE S DinB superfamily
COHLBPCN_03277 7.9e-108 yuaD
COHLBPCN_03278 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
COHLBPCN_03279 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
COHLBPCN_03280 1.1e-95 yuaC K Belongs to the GbsR family
COHLBPCN_03281 2.2e-91 yuaB
COHLBPCN_03282 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
COHLBPCN_03283 5.4e-237 ktrB P Potassium
COHLBPCN_03284 1e-38 yiaA S yiaA/B two helix domain
COHLBPCN_03285 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COHLBPCN_03286 6.2e-277 yubD P Major Facilitator Superfamily
COHLBPCN_03287 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
COHLBPCN_03289 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
COHLBPCN_03290 6.3e-197 yubA S transporter activity
COHLBPCN_03291 3.3e-183 ygjR S Oxidoreductase
COHLBPCN_03292 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
COHLBPCN_03293 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
COHLBPCN_03294 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
COHLBPCN_03295 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
COHLBPCN_03296 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
COHLBPCN_03297 5.1e-239 mcpA NT chemotaxis protein
COHLBPCN_03298 2.2e-295 mcpA NT chemotaxis protein
COHLBPCN_03299 1.5e-222 mcpA NT chemotaxis protein
COHLBPCN_03300 3.2e-225 mcpA NT chemotaxis protein
COHLBPCN_03301 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
COHLBPCN_03302 1e-35
COHLBPCN_03303 2.1e-72 yugU S Uncharacterised protein family UPF0047
COHLBPCN_03304 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
COHLBPCN_03305 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
COHLBPCN_03306 1.4e-116 yugP S Zn-dependent protease
COHLBPCN_03307 4.6e-39
COHLBPCN_03308 1.1e-53 mstX S Membrane-integrating protein Mistic
COHLBPCN_03309 1.7e-182 yugO P COG1226 Kef-type K transport systems
COHLBPCN_03310 1.3e-72 yugN S YugN-like family
COHLBPCN_03312 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
COHLBPCN_03313 2.8e-229 yugK C Dehydrogenase
COHLBPCN_03314 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
COHLBPCN_03315 1.1e-34 yuzA S Domain of unknown function (DUF378)
COHLBPCN_03316 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
COHLBPCN_03317 4.3e-200 yugH 2.6.1.1 E Aminotransferase
COHLBPCN_03318 1.6e-85 alaR K Transcriptional regulator
COHLBPCN_03319 1e-156 yugF I Hydrolase
COHLBPCN_03320 9.8e-42 yugE S Domain of unknown function (DUF1871)
COHLBPCN_03321 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
COHLBPCN_03322 4.6e-233 T PhoQ Sensor
COHLBPCN_03323 2e-70 kapB G Kinase associated protein B
COHLBPCN_03324 1.9e-115 kapD L the KinA pathway to sporulation
COHLBPCN_03326 3.5e-186 yuxJ EGP Major facilitator Superfamily
COHLBPCN_03327 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
COHLBPCN_03328 6.3e-75 yuxK S protein conserved in bacteria
COHLBPCN_03329 6.3e-78 yufK S Family of unknown function (DUF5366)
COHLBPCN_03330 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
COHLBPCN_03331 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
COHLBPCN_03332 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
COHLBPCN_03333 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
COHLBPCN_03334 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
COHLBPCN_03335 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
COHLBPCN_03336 1.3e-233 maeN C COG3493 Na citrate symporter
COHLBPCN_03337 1.9e-14
COHLBPCN_03338 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
COHLBPCN_03339 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COHLBPCN_03340 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COHLBPCN_03341 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COHLBPCN_03342 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COHLBPCN_03343 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COHLBPCN_03344 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
COHLBPCN_03345 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
COHLBPCN_03346 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COHLBPCN_03347 0.0 comP 2.7.13.3 T Histidine kinase
COHLBPCN_03349 2.5e-162 comQ H Polyprenyl synthetase
COHLBPCN_03351 1.1e-22 yuzC
COHLBPCN_03352 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
COHLBPCN_03353 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COHLBPCN_03354 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
COHLBPCN_03355 1.6e-67 yueI S Protein of unknown function (DUF1694)
COHLBPCN_03356 7.4e-39 yueH S YueH-like protein
COHLBPCN_03357 2.1e-32 yueG S Spore germination protein gerPA/gerPF
COHLBPCN_03358 1.9e-190 yueF S transporter activity
COHLBPCN_03359 6.1e-72 S Protein of unknown function (DUF2283)
COHLBPCN_03360 2.9e-24 S Protein of unknown function (DUF2642)
COHLBPCN_03361 4.8e-96 yueE S phosphohydrolase
COHLBPCN_03362 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_03363 6.6e-65 yueC S Family of unknown function (DUF5383)
COHLBPCN_03364 0.0 esaA S type VII secretion protein EsaA
COHLBPCN_03365 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
COHLBPCN_03366 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
COHLBPCN_03367 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
COHLBPCN_03368 2.8e-45 esxA S Belongs to the WXG100 family
COHLBPCN_03369 6.5e-229 yukF QT Transcriptional regulator
COHLBPCN_03370 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
COHLBPCN_03371 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
COHLBPCN_03372 3.8e-36 mbtH S MbtH-like protein
COHLBPCN_03373 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_03374 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
COHLBPCN_03375 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
COHLBPCN_03376 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
COHLBPCN_03377 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_03378 1.3e-167 besA S Putative esterase
COHLBPCN_03379 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
COHLBPCN_03380 1.1e-93 bioY S Biotin biosynthesis protein
COHLBPCN_03381 3.9e-211 yuiF S antiporter
COHLBPCN_03382 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
COHLBPCN_03383 1.2e-77 yuiD S protein conserved in bacteria
COHLBPCN_03384 9.5e-118 yuiC S protein conserved in bacteria
COHLBPCN_03385 8.4e-27 yuiB S Putative membrane protein
COHLBPCN_03386 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
COHLBPCN_03387 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
COHLBPCN_03389 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COHLBPCN_03390 9e-118 paiB K Putative FMN-binding domain
COHLBPCN_03391 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COHLBPCN_03392 3.7e-63 erpA S Belongs to the HesB IscA family
COHLBPCN_03393 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COHLBPCN_03394 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COHLBPCN_03395 3.2e-39 yuzB S Belongs to the UPF0349 family
COHLBPCN_03396 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
COHLBPCN_03397 3.5e-57 yuzD S protein conserved in bacteria
COHLBPCN_03398 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
COHLBPCN_03399 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
COHLBPCN_03400 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COHLBPCN_03401 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
COHLBPCN_03402 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
COHLBPCN_03403 2e-199 yutH S Spore coat protein
COHLBPCN_03404 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
COHLBPCN_03405 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COHLBPCN_03406 1e-75 yutE S Protein of unknown function DUF86
COHLBPCN_03407 9.7e-48 yutD S protein conserved in bacteria
COHLBPCN_03408 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
COHLBPCN_03409 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
COHLBPCN_03410 4.5e-196 lytH M Peptidase, M23
COHLBPCN_03411 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
COHLBPCN_03412 4.8e-48 yunC S Domain of unknown function (DUF1805)
COHLBPCN_03413 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
COHLBPCN_03414 2e-141 yunE S membrane transporter protein
COHLBPCN_03415 4.3e-171 yunF S Protein of unknown function DUF72
COHLBPCN_03416 3e-62 yunG
COHLBPCN_03417 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
COHLBPCN_03418 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
COHLBPCN_03419 2.1e-236 pbuX F Permease family
COHLBPCN_03420 1.3e-224 pbuX F xanthine
COHLBPCN_03421 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
COHLBPCN_03422 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
COHLBPCN_03423 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
COHLBPCN_03424 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
COHLBPCN_03425 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
COHLBPCN_03426 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
COHLBPCN_03427 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
COHLBPCN_03429 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
COHLBPCN_03430 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
COHLBPCN_03431 2.4e-169 bsn L Ribonuclease
COHLBPCN_03432 1.2e-205 msmX P Belongs to the ABC transporter superfamily
COHLBPCN_03433 1.1e-135 yurK K UTRA
COHLBPCN_03434 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
COHLBPCN_03435 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
COHLBPCN_03436 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
COHLBPCN_03437 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
COHLBPCN_03438 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
COHLBPCN_03439 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
COHLBPCN_03440 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
COHLBPCN_03442 1e-41
COHLBPCN_03443 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COHLBPCN_03444 3.5e-271 sufB O FeS cluster assembly
COHLBPCN_03445 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
COHLBPCN_03446 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COHLBPCN_03447 1.4e-245 sufD O assembly protein SufD
COHLBPCN_03448 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
COHLBPCN_03449 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COHLBPCN_03450 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
COHLBPCN_03451 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
COHLBPCN_03452 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COHLBPCN_03453 2.4e-56 yusD S SCP-2 sterol transfer family
COHLBPCN_03454 5.6e-55 traF CO Thioredoxin
COHLBPCN_03455 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
COHLBPCN_03456 1.1e-39 yusG S Protein of unknown function (DUF2553)
COHLBPCN_03457 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
COHLBPCN_03458 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
COHLBPCN_03459 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
COHLBPCN_03460 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
COHLBPCN_03461 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
COHLBPCN_03462 4.7e-09 S YuzL-like protein
COHLBPCN_03463 2.2e-165 fadM E Proline dehydrogenase
COHLBPCN_03464 5.1e-40
COHLBPCN_03465 3.2e-53 yusN M Coat F domain
COHLBPCN_03466 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
COHLBPCN_03467 3.8e-293 yusP P Major facilitator superfamily
COHLBPCN_03468 8.4e-66 yusQ S Tautomerase enzyme
COHLBPCN_03469 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_03470 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_03471 2.7e-160 yusT K LysR substrate binding domain
COHLBPCN_03472 3.8e-47 yusU S Protein of unknown function (DUF2573)
COHLBPCN_03473 1e-153 yusV 3.6.3.34 HP ABC transporter
COHLBPCN_03474 5.6e-66 S YusW-like protein
COHLBPCN_03475 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
COHLBPCN_03476 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
COHLBPCN_03477 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_03478 1.2e-79 dps P Ferritin-like domain
COHLBPCN_03479 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COHLBPCN_03480 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_03481 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
COHLBPCN_03482 4.3e-158 yuxN K Transcriptional regulator
COHLBPCN_03483 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COHLBPCN_03484 2.3e-24 S Protein of unknown function (DUF3970)
COHLBPCN_03485 2.2e-247 gerAA EG Spore germination protein
COHLBPCN_03486 9.1e-198 gerAB E Spore germination protein
COHLBPCN_03487 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
COHLBPCN_03488 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COHLBPCN_03489 5.5e-187 vraS 2.7.13.3 T Histidine kinase
COHLBPCN_03490 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
COHLBPCN_03491 9.3e-129 liaG S Putative adhesin
COHLBPCN_03492 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
COHLBPCN_03493 5.6e-62 liaI S membrane
COHLBPCN_03494 4.8e-227 yvqJ EGP Major facilitator Superfamily
COHLBPCN_03495 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
COHLBPCN_03496 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
COHLBPCN_03497 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_03498 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
COHLBPCN_03499 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_03500 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
COHLBPCN_03501 0.0 T PhoQ Sensor
COHLBPCN_03502 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_03503 3.6e-22
COHLBPCN_03504 1.8e-96 yvrI K RNA polymerase
COHLBPCN_03505 2.4e-19 S YvrJ protein family
COHLBPCN_03506 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
COHLBPCN_03507 1.3e-64 yvrL S Regulatory protein YrvL
COHLBPCN_03508 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
COHLBPCN_03509 7.1e-124 macB V ABC transporter, ATP-binding protein
COHLBPCN_03510 4.8e-176 M Efflux transporter rnd family, mfp subunit
COHLBPCN_03511 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
COHLBPCN_03512 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_03513 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COHLBPCN_03514 2.1e-179 fhuD P ABC transporter
COHLBPCN_03516 2.6e-237 yvsH E Arginine ornithine antiporter
COHLBPCN_03517 6.5e-16 S Small spore protein J (Spore_SspJ)
COHLBPCN_03518 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
COHLBPCN_03519 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
COHLBPCN_03520 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
COHLBPCN_03521 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
COHLBPCN_03522 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
COHLBPCN_03523 9.1e-158 yvgN S reductase
COHLBPCN_03524 5.4e-86 yvgO
COHLBPCN_03525 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
COHLBPCN_03526 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
COHLBPCN_03527 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
COHLBPCN_03528 0.0 helD 3.6.4.12 L DNA helicase
COHLBPCN_03529 4.1e-107 yvgT S membrane
COHLBPCN_03530 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
COHLBPCN_03531 1.6e-104 bdbD O Thioredoxin
COHLBPCN_03532 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
COHLBPCN_03533 0.0 copA 3.6.3.54 P P-type ATPase
COHLBPCN_03534 1.5e-29 copZ P Copper resistance protein CopZ
COHLBPCN_03535 2.2e-48 csoR S transcriptional
COHLBPCN_03536 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
COHLBPCN_03537 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COHLBPCN_03538 0.0 yvaC S Fusaric acid resistance protein-like
COHLBPCN_03539 5.7e-73 yvaD S Family of unknown function (DUF5360)
COHLBPCN_03540 2.8e-55 yvaE P Small Multidrug Resistance protein
COHLBPCN_03541 4.1e-101 K Bacterial regulatory proteins, tetR family
COHLBPCN_03542 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_03544 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
COHLBPCN_03545 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COHLBPCN_03546 5.6e-143 est 3.1.1.1 S Carboxylesterase
COHLBPCN_03547 2.4e-23 secG U Preprotein translocase subunit SecG
COHLBPCN_03548 3.7e-153 yvaM S Serine aminopeptidase, S33
COHLBPCN_03549 7.5e-36 yvzC K Transcriptional
COHLBPCN_03550 4e-69 K transcriptional
COHLBPCN_03551 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
COHLBPCN_03552 2.2e-54 yodB K transcriptional
COHLBPCN_03553 4.2e-226 NT chemotaxis protein
COHLBPCN_03554 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
COHLBPCN_03555 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COHLBPCN_03556 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
COHLBPCN_03557 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
COHLBPCN_03558 8.7e-61 yvbF K Belongs to the GbsR family
COHLBPCN_03559 7.9e-13 S Sporulation delaying protein SdpA
COHLBPCN_03560 7.6e-172
COHLBPCN_03561 4.4e-08
COHLBPCN_03562 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
COHLBPCN_03563 4.5e-45 sdpR K transcriptional
COHLBPCN_03564 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
COHLBPCN_03565 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COHLBPCN_03566 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
COHLBPCN_03567 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
COHLBPCN_03568 1.4e-98 yvbF K Belongs to the GbsR family
COHLBPCN_03569 6.4e-103 yvbG U UPF0056 membrane protein
COHLBPCN_03570 8.6e-113 yvbH S YvbH-like oligomerisation region
COHLBPCN_03571 4.2e-124 exoY M Membrane
COHLBPCN_03572 0.0 tcaA S response to antibiotic
COHLBPCN_03573 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
COHLBPCN_03574 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COHLBPCN_03575 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
COHLBPCN_03576 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COHLBPCN_03577 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COHLBPCN_03578 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COHLBPCN_03579 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
COHLBPCN_03580 1.6e-252 araE EGP Major facilitator Superfamily
COHLBPCN_03581 5.5e-203 araR K transcriptional
COHLBPCN_03582 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COHLBPCN_03583 3.9e-159 yvbU K Transcriptional regulator
COHLBPCN_03584 8.5e-157 yvbV EG EamA-like transporter family
COHLBPCN_03585 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
COHLBPCN_03586 4.3e-197 yvbX S Glycosyl hydrolase
COHLBPCN_03587 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
COHLBPCN_03588 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
COHLBPCN_03589 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
COHLBPCN_03590 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COHLBPCN_03591 8.9e-201 desK 2.7.13.3 T Histidine kinase
COHLBPCN_03592 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
COHLBPCN_03593 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
COHLBPCN_03594 2.6e-157 rsbQ S Alpha/beta hydrolase family
COHLBPCN_03595 1.4e-199 rsbU 3.1.3.3 T response regulator
COHLBPCN_03596 2.6e-252 galA 3.2.1.89 G arabinogalactan
COHLBPCN_03597 0.0 lacA 3.2.1.23 G beta-galactosidase
COHLBPCN_03598 3.2e-150 ganQ P transport
COHLBPCN_03599 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
COHLBPCN_03600 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
COHLBPCN_03601 1.8e-184 lacR K Transcriptional regulator
COHLBPCN_03602 1e-112 yvfI K COG2186 Transcriptional regulators
COHLBPCN_03603 1.4e-309 yvfH C L-lactate permease
COHLBPCN_03604 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
COHLBPCN_03605 1e-31 yvfG S YvfG protein
COHLBPCN_03606 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
COHLBPCN_03607 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
COHLBPCN_03608 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
COHLBPCN_03609 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
COHLBPCN_03610 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COHLBPCN_03611 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
COHLBPCN_03612 3.6e-207 epsI GM pyruvyl transferase
COHLBPCN_03613 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
COHLBPCN_03614 4.8e-207 epsG S EpsG family
COHLBPCN_03615 5.3e-220 epsF GT4 M Glycosyl transferases group 1
COHLBPCN_03616 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COHLBPCN_03617 2e-224 epsD GT4 M Glycosyl transferase 4-like
COHLBPCN_03618 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
COHLBPCN_03619 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
COHLBPCN_03620 4e-122 ywqC M biosynthesis protein
COHLBPCN_03621 5.7e-77 slr K transcriptional
COHLBPCN_03622 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
COHLBPCN_03624 4.6e-93 padC Q Phenolic acid decarboxylase
COHLBPCN_03625 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
COHLBPCN_03626 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COHLBPCN_03627 9.6e-266 pbpE V Beta-lactamase
COHLBPCN_03628 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
COHLBPCN_03629 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
COHLBPCN_03630 1.8e-295 yveA E amino acid
COHLBPCN_03631 2.6e-106 yvdT K Transcriptional regulator
COHLBPCN_03632 6.7e-51 ykkC P Small Multidrug Resistance protein
COHLBPCN_03633 4.1e-50 sugE P Small Multidrug Resistance protein
COHLBPCN_03634 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
COHLBPCN_03635 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
COHLBPCN_03636 1.5e-183 S Patatin-like phospholipase
COHLBPCN_03638 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COHLBPCN_03639 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
COHLBPCN_03640 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
COHLBPCN_03641 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
COHLBPCN_03642 1.2e-158 malA S Protein of unknown function (DUF1189)
COHLBPCN_03643 7.8e-149 malD P transport
COHLBPCN_03644 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
COHLBPCN_03645 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
COHLBPCN_03646 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
COHLBPCN_03647 3.6e-174 yvdE K Transcriptional regulator
COHLBPCN_03648 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
COHLBPCN_03649 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
COHLBPCN_03650 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
COHLBPCN_03651 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
COHLBPCN_03652 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COHLBPCN_03653 0.0 yxdM V ABC transporter (permease)
COHLBPCN_03654 5.6e-141 yvcR V ABC transporter, ATP-binding protein
COHLBPCN_03655 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
COHLBPCN_03656 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_03657 1.8e-33
COHLBPCN_03658 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
COHLBPCN_03659 1.6e-36 crh G Phosphocarrier protein Chr
COHLBPCN_03660 1.4e-170 whiA K May be required for sporulation
COHLBPCN_03661 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COHLBPCN_03662 5.7e-166 rapZ S Displays ATPase and GTPase activities
COHLBPCN_03663 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
COHLBPCN_03664 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COHLBPCN_03665 1.4e-102 usp CBM50 M protein conserved in bacteria
COHLBPCN_03666 2.4e-278 S COG0457 FOG TPR repeat
COHLBPCN_03667 0.0 msbA2 3.6.3.44 V ABC transporter
COHLBPCN_03669 0.0
COHLBPCN_03670 4.6e-121
COHLBPCN_03671 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
COHLBPCN_03672 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
COHLBPCN_03673 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
COHLBPCN_03674 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COHLBPCN_03675 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
COHLBPCN_03676 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
COHLBPCN_03677 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
COHLBPCN_03678 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
COHLBPCN_03679 4.5e-140 yvpB NU protein conserved in bacteria
COHLBPCN_03680 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
COHLBPCN_03681 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
COHLBPCN_03682 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
COHLBPCN_03683 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
COHLBPCN_03684 3.5e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COHLBPCN_03685 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COHLBPCN_03686 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
COHLBPCN_03687 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COHLBPCN_03688 3.6e-134 yvoA K transcriptional
COHLBPCN_03689 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
COHLBPCN_03690 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_03691 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
COHLBPCN_03692 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
COHLBPCN_03693 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_03694 2.7e-203 yvmA EGP Major facilitator Superfamily
COHLBPCN_03695 1.2e-50 yvlD S Membrane
COHLBPCN_03696 2.6e-26 pspB KT PspC domain
COHLBPCN_03697 3.4e-168 yvlB S Putative adhesin
COHLBPCN_03698 8e-49 yvlA
COHLBPCN_03699 6.7e-34 yvkN
COHLBPCN_03700 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
COHLBPCN_03701 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COHLBPCN_03702 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COHLBPCN_03703 1.2e-30 csbA S protein conserved in bacteria
COHLBPCN_03704 0.0 yvkC 2.7.9.2 GT Phosphotransferase
COHLBPCN_03705 7e-101 yvkB K Transcriptional regulator
COHLBPCN_03706 7.9e-228 yvkA EGP Major facilitator Superfamily
COHLBPCN_03707 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COHLBPCN_03708 5.3e-56 swrA S Swarming motility protein
COHLBPCN_03709 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
COHLBPCN_03710 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
COHLBPCN_03711 1.6e-123 ftsE D cell division ATP-binding protein FtsE
COHLBPCN_03712 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
COHLBPCN_03713 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
COHLBPCN_03714 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COHLBPCN_03715 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COHLBPCN_03716 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COHLBPCN_03717 2.8e-66
COHLBPCN_03718 1.9e-08 fliT S bacterial-type flagellum organization
COHLBPCN_03719 2.9e-69 fliS N flagellar protein FliS
COHLBPCN_03720 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
COHLBPCN_03721 6.1e-57 flaG N flagellar protein FlaG
COHLBPCN_03722 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
COHLBPCN_03723 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
COHLBPCN_03724 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
COHLBPCN_03725 2.6e-50 yviE
COHLBPCN_03726 1.1e-156 flgL N Belongs to the bacterial flagellin family
COHLBPCN_03727 1.2e-264 flgK N flagellar hook-associated protein
COHLBPCN_03728 2.4e-78 flgN NOU FlgN protein
COHLBPCN_03729 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
COHLBPCN_03730 7e-74 yvyF S flagellar protein
COHLBPCN_03731 2.7e-129 comFC S Phosphoribosyl transferase domain
COHLBPCN_03732 5.7e-46 comFB S Late competence development protein ComFB
COHLBPCN_03733 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
COHLBPCN_03734 7.3e-155 degV S protein conserved in bacteria
COHLBPCN_03735 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COHLBPCN_03736 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
COHLBPCN_03737 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
COHLBPCN_03738 6e-163 yvhJ K Transcriptional regulator
COHLBPCN_03739 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
COHLBPCN_03740 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
COHLBPCN_03741 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
COHLBPCN_03742 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
COHLBPCN_03743 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
COHLBPCN_03744 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COHLBPCN_03745 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
COHLBPCN_03746 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COHLBPCN_03747 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
COHLBPCN_03748 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COHLBPCN_03749 0.0 lytB 3.5.1.28 D Stage II sporulation protein
COHLBPCN_03750 6e-38
COHLBPCN_03751 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
COHLBPCN_03752 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COHLBPCN_03753 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COHLBPCN_03754 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COHLBPCN_03755 8.1e-257 ggaA M Glycosyltransferase like family 2
COHLBPCN_03757 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COHLBPCN_03758 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
COHLBPCN_03759 1.1e-150 tagG GM Transport permease protein
COHLBPCN_03760 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
COHLBPCN_03761 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
COHLBPCN_03762 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
COHLBPCN_03763 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COHLBPCN_03764 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
COHLBPCN_03765 1.2e-260
COHLBPCN_03766 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COHLBPCN_03767 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
COHLBPCN_03768 3.5e-266 gerBA EG Spore germination protein
COHLBPCN_03769 7.5e-200 gerBB E Spore germination protein
COHLBPCN_03770 7.6e-216 gerAC S Spore germination protein
COHLBPCN_03771 1.9e-248 ywtG EGP Major facilitator Superfamily
COHLBPCN_03772 8.4e-171 ywtF K Transcriptional regulator
COHLBPCN_03773 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
COHLBPCN_03774 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
COHLBPCN_03775 3.6e-21 ywtC
COHLBPCN_03776 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
COHLBPCN_03777 8.6e-70 pgsC S biosynthesis protein
COHLBPCN_03778 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
COHLBPCN_03779 1.9e-178 rbsR K transcriptional
COHLBPCN_03780 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COHLBPCN_03781 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
COHLBPCN_03782 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
COHLBPCN_03783 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
COHLBPCN_03784 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
COHLBPCN_03785 4.6e-94 batE T Sh3 type 3 domain protein
COHLBPCN_03786 3.6e-48 ywsA S Protein of unknown function (DUF3892)
COHLBPCN_03787 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
COHLBPCN_03788 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
COHLBPCN_03789 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
COHLBPCN_03790 1.1e-169 alsR K LysR substrate binding domain
COHLBPCN_03791 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
COHLBPCN_03792 7.5e-126 ywrJ
COHLBPCN_03793 7.6e-131 cotB
COHLBPCN_03794 1.2e-210 cotH M Spore Coat
COHLBPCN_03795 3.7e-12
COHLBPCN_03796 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
COHLBPCN_03797 2.9e-54 S Domain of unknown function (DUF4181)
COHLBPCN_03798 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
COHLBPCN_03799 2.1e-82 ywrC K Transcriptional regulator
COHLBPCN_03800 2.4e-104 ywrB P Chromate transporter
COHLBPCN_03801 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
COHLBPCN_03803 2.7e-102 ywqN S NAD(P)H-dependent
COHLBPCN_03804 2.9e-162 K Transcriptional regulator
COHLBPCN_03805 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
COHLBPCN_03806 1.7e-52 S MORN repeat variant
COHLBPCN_03807 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
COHLBPCN_03808 1.3e-38 ywqI S Family of unknown function (DUF5344)
COHLBPCN_03809 3.3e-15 S Domain of unknown function (DUF5082)
COHLBPCN_03810 3.4e-154 ywqG S Domain of unknown function (DUF1963)
COHLBPCN_03811 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COHLBPCN_03812 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
COHLBPCN_03813 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
COHLBPCN_03814 2e-116 ywqC M biosynthesis protein
COHLBPCN_03815 1.2e-17
COHLBPCN_03816 3.8e-309 ywqB S SWIM zinc finger
COHLBPCN_03817 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
COHLBPCN_03818 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
COHLBPCN_03819 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
COHLBPCN_03820 9.8e-58 ssbB L Single-stranded DNA-binding protein
COHLBPCN_03821 1.3e-66 ywpG
COHLBPCN_03822 1.1e-66 ywpF S YwpF-like protein
COHLBPCN_03823 8e-51 srtA 3.4.22.70 M Sortase family
COHLBPCN_03824 1.4e-153 ywpD T Histidine kinase
COHLBPCN_03825 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COHLBPCN_03826 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COHLBPCN_03827 2.1e-199 S aspartate phosphatase
COHLBPCN_03828 1.5e-141 flhP N flagellar basal body
COHLBPCN_03829 6.9e-126 flhO N flagellar basal body
COHLBPCN_03830 3.5e-180 mbl D Rod shape-determining protein
COHLBPCN_03831 3e-44 spoIIID K Stage III sporulation protein D
COHLBPCN_03832 2.1e-70 ywoH K COG1846 Transcriptional regulators
COHLBPCN_03833 2.7e-211 ywoG EGP Major facilitator Superfamily
COHLBPCN_03834 1.2e-231 ywoF P Right handed beta helix region
COHLBPCN_03835 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
COHLBPCN_03836 4.4e-242 ywoD EGP Major facilitator superfamily
COHLBPCN_03837 4e-104 phzA Q Isochorismatase family
COHLBPCN_03838 1.2e-77
COHLBPCN_03839 2.5e-225 amt P Ammonium transporter
COHLBPCN_03840 1.6e-58 nrgB K Belongs to the P(II) protein family
COHLBPCN_03841 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
COHLBPCN_03842 3.5e-73 ywnJ S VanZ like family
COHLBPCN_03843 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
COHLBPCN_03844 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
COHLBPCN_03845 2.7e-14 ywnC S Family of unknown function (DUF5362)
COHLBPCN_03846 2.2e-70 ywnF S Family of unknown function (DUF5392)
COHLBPCN_03847 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COHLBPCN_03848 4.1e-144 mta K transcriptional
COHLBPCN_03849 2.6e-59 ywnC S Family of unknown function (DUF5362)
COHLBPCN_03850 1.6e-114 ywnB S NAD(P)H-binding
COHLBPCN_03851 1.7e-64 ywnA K Transcriptional regulator
COHLBPCN_03852 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
COHLBPCN_03853 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
COHLBPCN_03854 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
COHLBPCN_03856 3.8e-11 csbD K CsbD-like
COHLBPCN_03857 3e-84 ywmF S Peptidase M50
COHLBPCN_03858 1.3e-103 S response regulator aspartate phosphatase
COHLBPCN_03859 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
COHLBPCN_03860 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
COHLBPCN_03862 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
COHLBPCN_03863 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
COHLBPCN_03864 2e-178 spoIID D Stage II sporulation protein D
COHLBPCN_03865 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COHLBPCN_03866 1.6e-134 ywmB S TATA-box binding
COHLBPCN_03867 1.3e-32 ywzB S membrane
COHLBPCN_03868 4.3e-88 ywmA
COHLBPCN_03869 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COHLBPCN_03870 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COHLBPCN_03871 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COHLBPCN_03872 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COHLBPCN_03873 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COHLBPCN_03874 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COHLBPCN_03875 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COHLBPCN_03876 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
COHLBPCN_03877 2.5e-62 atpI S ATP synthase
COHLBPCN_03878 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COHLBPCN_03879 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COHLBPCN_03880 7.2e-95 ywlG S Belongs to the UPF0340 family
COHLBPCN_03881 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
COHLBPCN_03882 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COHLBPCN_03883 1.7e-91 mntP P Probably functions as a manganese efflux pump
COHLBPCN_03884 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COHLBPCN_03885 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
COHLBPCN_03886 6.1e-112 spoIIR S stage II sporulation protein R
COHLBPCN_03887 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
COHLBPCN_03889 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COHLBPCN_03890 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COHLBPCN_03891 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COHLBPCN_03892 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
COHLBPCN_03893 8.6e-160 ywkB S Membrane transport protein
COHLBPCN_03894 0.0 sfcA 1.1.1.38 C malic enzyme
COHLBPCN_03895 2.4e-104 tdk 2.7.1.21 F thymidine kinase
COHLBPCN_03896 1.1e-32 rpmE J Binds the 23S rRNA
COHLBPCN_03897 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COHLBPCN_03898 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
COHLBPCN_03899 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COHLBPCN_03900 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COHLBPCN_03901 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
COHLBPCN_03902 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
COHLBPCN_03903 2.4e-92 ywjG S Domain of unknown function (DUF2529)
COHLBPCN_03904 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COHLBPCN_03905 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COHLBPCN_03906 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
COHLBPCN_03907 0.0 fadF C COG0247 Fe-S oxidoreductase
COHLBPCN_03908 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
COHLBPCN_03909 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
COHLBPCN_03910 2.7e-42 ywjC
COHLBPCN_03911 4.8e-96 ywjB H RibD C-terminal domain
COHLBPCN_03912 0.0 ywjA V ABC transporter
COHLBPCN_03913 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COHLBPCN_03914 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
COHLBPCN_03915 2.4e-98 narJ 1.7.5.1 C nitrate reductase
COHLBPCN_03916 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
COHLBPCN_03917 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COHLBPCN_03918 7e-86 arfM T cyclic nucleotide binding
COHLBPCN_03919 4.3e-140 ywiC S YwiC-like protein
COHLBPCN_03920 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
COHLBPCN_03921 9.8e-214 narK P COG2223 Nitrate nitrite transporter
COHLBPCN_03922 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COHLBPCN_03923 4.7e-73 ywiB S protein conserved in bacteria
COHLBPCN_03924 1e-07 S Bacteriocin subtilosin A
COHLBPCN_03925 2.6e-271 C Fe-S oxidoreductases
COHLBPCN_03927 3.3e-132 cbiO V ABC transporter
COHLBPCN_03928 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
COHLBPCN_03929 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
COHLBPCN_03930 1.2e-249 L Peptidase, M16
COHLBPCN_03932 2.9e-249 ywhL CO amine dehydrogenase activity
COHLBPCN_03933 2.5e-205 ywhK CO amine dehydrogenase activity
COHLBPCN_03934 2.3e-79 S aspartate phosphatase
COHLBPCN_03936 1e-84 ywhH S Aminoacyl-tRNA editing domain
COHLBPCN_03937 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
COHLBPCN_03938 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
COHLBPCN_03939 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COHLBPCN_03940 5.2e-95 ywhD S YwhD family
COHLBPCN_03941 5.1e-119 ywhC S Peptidase family M50
COHLBPCN_03942 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
COHLBPCN_03943 3.3e-71 ywhA K Transcriptional regulator
COHLBPCN_03944 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COHLBPCN_03946 2.6e-242 mmr U Major Facilitator Superfamily
COHLBPCN_03947 2.8e-79 yffB K Transcriptional regulator
COHLBPCN_03948 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
COHLBPCN_03949 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
COHLBPCN_03950 3.1e-36 ywzC S Belongs to the UPF0741 family
COHLBPCN_03951 1.6e-111 rsfA_1
COHLBPCN_03952 5.2e-159 ywfM EG EamA-like transporter family
COHLBPCN_03953 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
COHLBPCN_03954 9.2e-164 cysL K Transcriptional regulator
COHLBPCN_03955 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
COHLBPCN_03956 1.1e-146 ywfI C May function as heme-dependent peroxidase
COHLBPCN_03957 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
COHLBPCN_03958 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
COHLBPCN_03959 2.9e-210 bacE EGP Major facilitator Superfamily
COHLBPCN_03960 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
COHLBPCN_03961 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COHLBPCN_03962 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
COHLBPCN_03963 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
COHLBPCN_03964 4.6e-206 ywfA EGP Major facilitator Superfamily
COHLBPCN_03965 4e-262 lysP E amino acid
COHLBPCN_03966 0.0 rocB E arginine degradation protein
COHLBPCN_03967 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
COHLBPCN_03968 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
COHLBPCN_03969 1.8e-78
COHLBPCN_03970 3.5e-87 spsL 5.1.3.13 M Spore Coat
COHLBPCN_03971 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COHLBPCN_03972 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COHLBPCN_03973 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COHLBPCN_03974 1.7e-190 spsG M Spore Coat
COHLBPCN_03975 9.7e-132 spsF M Spore Coat
COHLBPCN_03976 3.2e-214 spsE 2.5.1.56 M acid synthase
COHLBPCN_03977 4e-164 spsD 2.3.1.210 K Spore Coat
COHLBPCN_03978 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
COHLBPCN_03979 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
COHLBPCN_03980 2.8e-145 spsA M Spore Coat
COHLBPCN_03981 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
COHLBPCN_03982 4.3e-59 ywdK S small membrane protein
COHLBPCN_03983 1.3e-238 ywdJ F Xanthine uracil
COHLBPCN_03984 7.7e-49 ywdI S Family of unknown function (DUF5327)
COHLBPCN_03985 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
COHLBPCN_03986 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COHLBPCN_03987 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
COHLBPCN_03989 1.4e-113 ywdD
COHLBPCN_03990 1.3e-57 pex K Transcriptional regulator PadR-like family
COHLBPCN_03991 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COHLBPCN_03992 2e-28 ywdA
COHLBPCN_03993 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
COHLBPCN_03994 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COHLBPCN_03995 1e-139 focA P Formate/nitrite transporter
COHLBPCN_03996 2.4e-150 sacT K transcriptional antiterminator
COHLBPCN_03998 0.0 vpr O Belongs to the peptidase S8 family
COHLBPCN_03999 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COHLBPCN_04000 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
COHLBPCN_04001 2.9e-202 rodA D Belongs to the SEDS family
COHLBPCN_04002 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
COHLBPCN_04003 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
COHLBPCN_04004 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
COHLBPCN_04005 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
COHLBPCN_04006 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
COHLBPCN_04007 1e-35 ywzA S membrane
COHLBPCN_04008 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COHLBPCN_04009 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COHLBPCN_04010 9.5e-60 gtcA S GtrA-like protein
COHLBPCN_04011 2.2e-122 ywcC K transcriptional regulator
COHLBPCN_04013 9.8e-49 ywcB S Protein of unknown function, DUF485
COHLBPCN_04014 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COHLBPCN_04015 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
COHLBPCN_04016 2.6e-225 ywbN P Dyp-type peroxidase family protein
COHLBPCN_04017 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
COHLBPCN_04018 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
COHLBPCN_04019 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COHLBPCN_04020 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COHLBPCN_04021 4.3e-153 ywbI K Transcriptional regulator
COHLBPCN_04022 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
COHLBPCN_04023 2.3e-111 ywbG M effector of murein hydrolase
COHLBPCN_04024 1.9e-209 ywbF EGP Major facilitator Superfamily
COHLBPCN_04025 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
COHLBPCN_04026 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
COHLBPCN_04027 4.4e-67 ywbC 4.4.1.5 E glyoxalase
COHLBPCN_04028 1.8e-127 ywbB S Protein of unknown function (DUF2711)
COHLBPCN_04029 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COHLBPCN_04030 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
COHLBPCN_04031 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COHLBPCN_04032 4e-153 sacY K transcriptional antiterminator
COHLBPCN_04033 7e-169 gspA M General stress
COHLBPCN_04034 1.7e-128 ywaF S Integral membrane protein
COHLBPCN_04035 8.1e-88 ywaE K Transcriptional regulator
COHLBPCN_04036 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COHLBPCN_04037 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
COHLBPCN_04038 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
COHLBPCN_04039 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
COHLBPCN_04040 5e-14 S D-Ala-teichoic acid biosynthesis protein
COHLBPCN_04041 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_04042 1.2e-232 dltB M membrane protein involved in D-alanine export
COHLBPCN_04043 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COHLBPCN_04044 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COHLBPCN_04045 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_04046 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
COHLBPCN_04047 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
COHLBPCN_04048 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
COHLBPCN_04049 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COHLBPCN_04050 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
COHLBPCN_04051 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
COHLBPCN_04052 1.1e-19 yxzF
COHLBPCN_04053 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COHLBPCN_04054 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
COHLBPCN_04055 2.1e-216 yxlH EGP Major facilitator Superfamily
COHLBPCN_04056 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
COHLBPCN_04057 1.5e-166 yxlF V ABC transporter, ATP-binding protein
COHLBPCN_04058 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
COHLBPCN_04059 1.2e-31
COHLBPCN_04060 3.9e-48 yxlC S Family of unknown function (DUF5345)
COHLBPCN_04061 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
COHLBPCN_04062 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
COHLBPCN_04063 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COHLBPCN_04064 0.0 cydD V ATP-binding protein
COHLBPCN_04065 0.0 cydD V ATP-binding
COHLBPCN_04066 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
COHLBPCN_04067 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
COHLBPCN_04068 1.5e-229 cimH C COG3493 Na citrate symporter
COHLBPCN_04069 0.0 3.4.24.84 O Peptidase family M48
COHLBPCN_04071 3e-156 yxkH G Polysaccharide deacetylase
COHLBPCN_04072 5.9e-205 msmK P Belongs to the ABC transporter superfamily
COHLBPCN_04073 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
COHLBPCN_04074 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COHLBPCN_04075 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COHLBPCN_04076 4.1e-73 yxkC S Domain of unknown function (DUF4352)
COHLBPCN_04077 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COHLBPCN_04078 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
COHLBPCN_04079 1.9e-166 yxjO K LysR substrate binding domain
COHLBPCN_04080 2.4e-78 S Protein of unknown function (DUF1453)
COHLBPCN_04081 1.5e-193 yxjM T Signal transduction histidine kinase
COHLBPCN_04082 8.9e-116 K helix_turn_helix, Lux Regulon
COHLBPCN_04083 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COHLBPCN_04086 1e-87 yxjI S LURP-one-related
COHLBPCN_04087 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
COHLBPCN_04088 1e-220 yxjG 2.1.1.14 E Methionine synthase
COHLBPCN_04089 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
COHLBPCN_04090 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
COHLBPCN_04091 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
COHLBPCN_04092 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
COHLBPCN_04093 3.1e-161 rlmA 2.1.1.187 Q Methyltransferase domain
COHLBPCN_04094 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COHLBPCN_04095 1.2e-22 T Domain of unknown function (DUF4163)
COHLBPCN_04096 2.7e-48 yxiS
COHLBPCN_04097 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
COHLBPCN_04098 6.6e-224 citH C Citrate transporter
COHLBPCN_04099 5e-144 exoK GH16 M licheninase activity
COHLBPCN_04100 8.3e-151 licT K transcriptional antiterminator
COHLBPCN_04101 6.6e-114
COHLBPCN_04102 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
COHLBPCN_04103 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
COHLBPCN_04104 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
COHLBPCN_04107 1.6e-48 yxiJ S YxiJ-like protein
COHLBPCN_04108 1.2e-96 yxiI S Protein of unknown function (DUF2716)
COHLBPCN_04109 3.8e-81
COHLBPCN_04110 4.9e-46
COHLBPCN_04111 3.7e-75 yxiG
COHLBPCN_04112 6.4e-63
COHLBPCN_04113 1.7e-84
COHLBPCN_04114 1.5e-71 yxxG
COHLBPCN_04115 0.0 wapA M COG3209 Rhs family protein
COHLBPCN_04116 2.9e-168 yxxF EG EamA-like transporter family
COHLBPCN_04117 1.1e-72 yxiE T Belongs to the universal stress protein A family
COHLBPCN_04118 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COHLBPCN_04119 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COHLBPCN_04120 3.6e-51
COHLBPCN_04121 2.2e-78 S SMI1 / KNR4 family
COHLBPCN_04122 0.0 S nuclease activity
COHLBPCN_04123 3.6e-39 yxiC S Family of unknown function (DUF5344)
COHLBPCN_04124 2.1e-21 S Domain of unknown function (DUF5082)
COHLBPCN_04125 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
COHLBPCN_04126 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
COHLBPCN_04127 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
COHLBPCN_04128 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
COHLBPCN_04129 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
COHLBPCN_04130 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
COHLBPCN_04131 6.1e-252 lysP E amino acid
COHLBPCN_04132 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
COHLBPCN_04133 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COHLBPCN_04134 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COHLBPCN_04135 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
COHLBPCN_04136 3e-153 yxxB S Domain of Unknown Function (DUF1206)
COHLBPCN_04137 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
COHLBPCN_04138 2e-255 yxeQ S MmgE/PrpD family
COHLBPCN_04139 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
COHLBPCN_04140 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
COHLBPCN_04141 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
COHLBPCN_04142 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
COHLBPCN_04143 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COHLBPCN_04144 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COHLBPCN_04146 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
COHLBPCN_04147 6.2e-151 yidA S hydrolases of the HAD superfamily
COHLBPCN_04150 1.3e-20 yxeE
COHLBPCN_04151 1.9e-16 yxeD
COHLBPCN_04152 8.5e-69
COHLBPCN_04153 6e-177 fhuD P ABC transporter
COHLBPCN_04154 1.5e-58 yxeA S Protein of unknown function (DUF1093)
COHLBPCN_04155 0.0 yxdM V ABC transporter (permease)
COHLBPCN_04156 9.4e-141 yxdL V ABC transporter, ATP-binding protein
COHLBPCN_04157 1.3e-182 T PhoQ Sensor
COHLBPCN_04158 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_04159 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
COHLBPCN_04160 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
COHLBPCN_04161 2.3e-167 iolH G Xylose isomerase-like TIM barrel
COHLBPCN_04162 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
COHLBPCN_04163 1.3e-235 iolF EGP Major facilitator Superfamily
COHLBPCN_04164 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
COHLBPCN_04165 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
COHLBPCN_04166 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
COHLBPCN_04167 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
COHLBPCN_04168 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COHLBPCN_04169 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
COHLBPCN_04170 3.7e-176 iolS C Aldo keto reductase
COHLBPCN_04172 8.3e-48 yxcD S Protein of unknown function (DUF2653)
COHLBPCN_04173 2.3e-246 csbC EGP Major facilitator Superfamily
COHLBPCN_04174 0.0 htpG O Molecular chaperone. Has ATPase activity
COHLBPCN_04176 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
COHLBPCN_04177 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
COHLBPCN_04178 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
COHLBPCN_04179 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
COHLBPCN_04180 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
COHLBPCN_04181 3.3e-127 yxbB Q Met-10+ like-protein
COHLBPCN_04182 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
COHLBPCN_04183 1.1e-86 yxnB
COHLBPCN_04184 0.0 asnB 6.3.5.4 E Asparagine synthase
COHLBPCN_04185 7.6e-214 yxaM U MFS_1 like family
COHLBPCN_04186 6.8e-93 S PQQ-like domain
COHLBPCN_04187 3.5e-65 S Family of unknown function (DUF5391)
COHLBPCN_04188 1.1e-75 yxaI S membrane protein domain
COHLBPCN_04189 1.4e-228 P Protein of unknown function (DUF418)
COHLBPCN_04190 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
COHLBPCN_04191 7.1e-101 yxaF K Transcriptional regulator
COHLBPCN_04192 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COHLBPCN_04193 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
COHLBPCN_04194 5.2e-50 S LrgA family
COHLBPCN_04195 2.6e-118 yxaC M effector of murein hydrolase
COHLBPCN_04196 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
COHLBPCN_04197 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COHLBPCN_04198 7.3e-127 gntR K transcriptional
COHLBPCN_04199 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
COHLBPCN_04200 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
COHLBPCN_04201 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COHLBPCN_04202 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
COHLBPCN_04203 3.8e-287 ahpF O Alkyl hydroperoxide reductase
COHLBPCN_04204 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COHLBPCN_04205 2.5e-19 bglF G phosphotransferase system
COHLBPCN_04206 1.3e-128 yydK K Transcriptional regulator
COHLBPCN_04207 7.6e-13
COHLBPCN_04208 3.3e-119 S ABC-2 family transporter protein
COHLBPCN_04209 1.8e-110 prrC P ABC transporter
COHLBPCN_04210 8.4e-134 yydH O Peptidase M50
COHLBPCN_04211 7.7e-185 S Radical SAM superfamily
COHLBPCN_04212 8e-12
COHLBPCN_04213 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
COHLBPCN_04214 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
COHLBPCN_04215 3.5e-65
COHLBPCN_04216 7.3e-280 S Calcineurin-like phosphoesterase
COHLBPCN_04217 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COHLBPCN_04218 1.1e-09 S YyzF-like protein
COHLBPCN_04219 4.2e-71
COHLBPCN_04220 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
COHLBPCN_04222 2.1e-33 yycQ S Protein of unknown function (DUF2651)
COHLBPCN_04223 1.6e-221 yycP
COHLBPCN_04224 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
COHLBPCN_04225 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
COHLBPCN_04226 5e-188 S aspartate phosphatase
COHLBPCN_04228 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
COHLBPCN_04229 9.7e-261 rocE E amino acid
COHLBPCN_04230 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
COHLBPCN_04231 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
COHLBPCN_04232 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COHLBPCN_04233 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
COHLBPCN_04234 7.3e-155 yycI S protein conserved in bacteria
COHLBPCN_04235 3.6e-260 yycH S protein conserved in bacteria
COHLBPCN_04236 0.0 vicK 2.7.13.3 T Histidine kinase
COHLBPCN_04237 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COHLBPCN_04242 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COHLBPCN_04243 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COHLBPCN_04244 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COHLBPCN_04245 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
COHLBPCN_04247 1.9e-15 yycC K YycC-like protein
COHLBPCN_04248 8.4e-221 yeaN P COG2807 Cyanate permease
COHLBPCN_04249 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COHLBPCN_04250 2.2e-73 rplI J binds to the 23S rRNA
COHLBPCN_04251 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COHLBPCN_04252 2.9e-160 yybS S membrane
COHLBPCN_04254 3.9e-84 cotF M Spore coat protein
COHLBPCN_04255 1.4e-68 ydeP3 K Transcriptional regulator
COHLBPCN_04256 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
COHLBPCN_04257 1.3e-70
COHLBPCN_04259 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
COHLBPCN_04260 1e-16
COHLBPCN_04261 1.3e-78 yybN S Protein of unknown function (DUF2712)
COHLBPCN_04262 4.1e-125
COHLBPCN_04263 9e-122
COHLBPCN_04264 2e-127 S Protein of unknown function (DUF2705)
COHLBPCN_04265 2.6e-115 V ATPases associated with a variety of cellular activities
COHLBPCN_04266 6.2e-132
COHLBPCN_04267 5.9e-67 yybH S SnoaL-like domain
COHLBPCN_04268 3e-124 yybG S Pentapeptide repeat-containing protein
COHLBPCN_04269 3.2e-220 ynfM EGP Major facilitator Superfamily
COHLBPCN_04270 2.1e-165 yybE K Transcriptional regulator
COHLBPCN_04271 2e-79 yjcF S Acetyltransferase (GNAT) domain
COHLBPCN_04272 2.7e-77 yybC
COHLBPCN_04273 3e-127 S Metallo-beta-lactamase superfamily
COHLBPCN_04274 5.6e-77 yybA 2.3.1.57 K transcriptional
COHLBPCN_04275 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
COHLBPCN_04276 1.5e-101 yyaS S Membrane
COHLBPCN_04277 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
COHLBPCN_04278 5.4e-67 yyaQ S YjbR
COHLBPCN_04279 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
COHLBPCN_04280 1.7e-249 tetL EGP Major facilitator Superfamily
COHLBPCN_04281 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
COHLBPCN_04282 5.1e-61 yyaN K MerR HTH family regulatory protein
COHLBPCN_04283 3.3e-161 yyaM EG EamA-like transporter family
COHLBPCN_04284 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
COHLBPCN_04285 9.5e-169 yyaK S CAAX protease self-immunity
COHLBPCN_04286 8.5e-246 EGP Major facilitator superfamily
COHLBPCN_04287 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
COHLBPCN_04288 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COHLBPCN_04289 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
COHLBPCN_04290 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
COHLBPCN_04291 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COHLBPCN_04292 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COHLBPCN_04293 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
COHLBPCN_04294 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COHLBPCN_04295 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COHLBPCN_04296 2.3e-33 yyzM S protein conserved in bacteria
COHLBPCN_04297 8.1e-177 yyaD S Membrane
COHLBPCN_04298 1.6e-111 yyaC S Sporulation protein YyaC
COHLBPCN_04299 2.1e-149 spo0J K Belongs to the ParB family
COHLBPCN_04300 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
COHLBPCN_04301 1.5e-74 S Bacterial PH domain
COHLBPCN_04302 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
COHLBPCN_04303 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
COHLBPCN_04304 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COHLBPCN_04305 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COHLBPCN_04306 6.5e-108 jag S single-stranded nucleic acid binding R3H
COHLBPCN_04307 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COHLBPCN_04308 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COHLBPCN_04310 3.3e-12 S peptidoglycan catabolic process
COHLBPCN_04311 5.7e-147 M phage tail tape measure protein
COHLBPCN_04313 1.6e-40 S Phage tail tube protein
COHLBPCN_04314 2.5e-07
COHLBPCN_04315 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
COHLBPCN_04316 1.2e-10 S Phage head-tail joining protein
COHLBPCN_04317 1.4e-21 S DNA packaging
COHLBPCN_04319 6.8e-87 S Phage capsid family
COHLBPCN_04320 1.9e-55 S Caudovirus prohead serine protease
COHLBPCN_04321 1.6e-106 S Phage portal protein
COHLBPCN_04324 8.1e-29 S Phage terminase, small subunit
COHLBPCN_04327 1.9e-177 S response regulator aspartate phosphatase
COHLBPCN_04329 9.7e-83
COHLBPCN_04331 1.2e-68 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
COHLBPCN_04332 1.6e-22 yocH 3.5.1.28 M 3D domain
COHLBPCN_04335 3.6e-73 L integrase family
COHLBPCN_04336 2.9e-52
COHLBPCN_04339 2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
COHLBPCN_04340 8.1e-20
COHLBPCN_04342 1.5e-31 yxcD S Protein of unknown function (DUF2653)
COHLBPCN_04343 2e-07
COHLBPCN_04345 2.5e-34
COHLBPCN_04346 8.2e-48 F Nucleoside 2-deoxyribosyltransferase
COHLBPCN_04349 1.9e-64 S AAA domain
COHLBPCN_04350 3.3e-277 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
COHLBPCN_04351 4.3e-104 S Ribonucleotide reductase, small chain
COHLBPCN_04352 1.5e-11 fld C Flavodoxin
COHLBPCN_04354 4e-39
COHLBPCN_04356 1.5e-24
COHLBPCN_04357 1.3e-15
COHLBPCN_04358 6.1e-110 S DNA helicase activity
COHLBPCN_04359 1e-89 S DNA primase activity
COHLBPCN_04361 1.4e-86 S exonuclease activity
COHLBPCN_04362 2.4e-15 K Transcriptional regulator
COHLBPCN_04363 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
COHLBPCN_04365 1.3e-06 yfbR S HD containing hydrolase-like enzyme
COHLBPCN_04368 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COHLBPCN_04370 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
COHLBPCN_04372 0.0 S Bacterial DNA polymerase III alpha subunit
COHLBPCN_04376 1.8e-21 2.7.4.8 F Guanylate kinase homologues.
COHLBPCN_04377 1.6e-17 S Endodeoxyribonuclease RusA
COHLBPCN_04383 9.1e-11 tdk 2.7.1.21 F Psort location Cytoplasmic, score
COHLBPCN_04385 4e-15 repA S Replication initiator protein A (RepA) N-terminus
COHLBPCN_04386 2.6e-184 S DNA gyrase B
COHLBPCN_04387 7e-148 S DNA gyrase/topoisomerase IV, subunit A
COHLBPCN_04388 3.4e-57 traC L Domain of unknown function (DUF1738)
COHLBPCN_04394 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COHLBPCN_04396 6e-128
COHLBPCN_04397 1.5e-20 L COG3666 Transposase and inactivated derivatives
COHLBPCN_04398 2.7e-61
COHLBPCN_04400 1.5e-63 S Immunity protein 70
COHLBPCN_04401 4.6e-174 A Pre-toxin TG
COHLBPCN_04402 1.2e-97 S Phage integrase family
COHLBPCN_04403 4.4e-106 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
COHLBPCN_04404 4.3e-09 S SPP1 phage holin
COHLBPCN_04407 3e-12
COHLBPCN_04408 4.6e-76 S N-acetylmuramoyl-L-alanine amidase activity
COHLBPCN_04409 1.1e-23
COHLBPCN_04410 2.4e-147 S Phage minor structural protein
COHLBPCN_04411 1e-176 S Phage tail protein
COHLBPCN_04412 2.9e-66 L Transglycosylase SLT domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)