ORF_ID e_value Gene_name EC_number CAZy COGs Description
CFCHMLLK_00001 1.4e-33 L PFAM Integrase, catalytic core
CFCHMLLK_00004 1.3e-94 ywlG S Belongs to the UPF0340 family
CFCHMLLK_00005 1.1e-84 treR K trehalose operon
CFCHMLLK_00007 1.1e-54 treB 2.7.1.201 G PTS System
CFCHMLLK_00008 1.9e-64 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CFCHMLLK_00009 5.9e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CFCHMLLK_00010 0.0 pepO 3.4.24.71 O Peptidase family M13
CFCHMLLK_00011 7.4e-65 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
CFCHMLLK_00012 7.4e-103 1.1.1.1, 1.1.99.1, 1.2.1.10, 1.2.1.18, 1.2.1.27, 1.2.1.3 C Dehydrogenase
CFCHMLLK_00013 4.6e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CFCHMLLK_00014 1.1e-80 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CFCHMLLK_00015 8.4e-23 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CFCHMLLK_00016 4.1e-278 thrC 4.2.3.1 E Threonine synthase
CFCHMLLK_00017 7.1e-226 norM V Mate efflux family protein
CFCHMLLK_00018 1.4e-57 asp S cog cog1302
CFCHMLLK_00019 1.1e-303 yloV S kinase related to dihydroxyacetone kinase
CFCHMLLK_00020 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CFCHMLLK_00021 1.3e-279 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CFCHMLLK_00022 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
CFCHMLLK_00023 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
CFCHMLLK_00024 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFCHMLLK_00025 2.1e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFCHMLLK_00026 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFCHMLLK_00027 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFCHMLLK_00028 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFCHMLLK_00029 3.8e-68 S cog cog4699
CFCHMLLK_00030 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFCHMLLK_00031 9.2e-153 cglB NU type II secretion system
CFCHMLLK_00032 8.5e-43 comGC U Required for transformation and DNA binding
CFCHMLLK_00033 1.8e-57 cglD NU Competence protein
CFCHMLLK_00034 1.4e-15 NU Type II secretory pathway pseudopilin
CFCHMLLK_00035 1.5e-71 comGF U Competence protein ComGF
CFCHMLLK_00036 6.8e-13 comGF U Putative Competence protein ComGF
CFCHMLLK_00037 1.7e-176 ytxK 2.1.1.72 L DNA methylase
CFCHMLLK_00038 4.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFCHMLLK_00039 8.8e-27 lanR K sequence-specific DNA binding
CFCHMLLK_00040 1.4e-33 V CAAX protease self-immunity
CFCHMLLK_00041 1.1e-66 V CAAX protease self-immunity
CFCHMLLK_00043 9.6e-110 S CAAX amino terminal protease family protein
CFCHMLLK_00044 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFCHMLLK_00045 4.4e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CFCHMLLK_00046 4.1e-09 S Domain of unknown function (DUF4651)
CFCHMLLK_00047 2.1e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CFCHMLLK_00048 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFCHMLLK_00049 2.1e-188 yeeE S Sulphur transport
CFCHMLLK_00050 8.3e-37 yeeD O sulfur carrier activity
CFCHMLLK_00051 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CFCHMLLK_00052 4.6e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CFCHMLLK_00055 2e-157 rrmA 2.1.1.187 Q methyltransferase
CFCHMLLK_00056 3.4e-64 S phosphatase activity
CFCHMLLK_00057 2.7e-48 S glycolate biosynthetic process
CFCHMLLK_00058 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CFCHMLLK_00059 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CFCHMLLK_00060 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFCHMLLK_00061 2.6e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CFCHMLLK_00062 3e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CFCHMLLK_00063 4.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CFCHMLLK_00064 1.2e-32 XK27_08585 S Psort location CytoplasmicMembrane, score
CFCHMLLK_00065 1.3e-54 fnt P Formate nitrite transporter
CFCHMLLK_00066 2.9e-136 XK27_09615 C reductase
CFCHMLLK_00067 4.4e-61 XK27_09615 C reductase
CFCHMLLK_00068 7.3e-77 XK27_09620 S reductase
CFCHMLLK_00069 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
CFCHMLLK_00070 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CFCHMLLK_00071 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CFCHMLLK_00072 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
CFCHMLLK_00073 1.3e-58 WQ51_05710 S Mitochondrial biogenesis AIM24
CFCHMLLK_00074 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
CFCHMLLK_00075 9.2e-51 S Protein of unknown function (DUF3397)
CFCHMLLK_00076 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFCHMLLK_00077 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CFCHMLLK_00078 3.5e-73 amiA E transmembrane transport
CFCHMLLK_00079 2.5e-80 amiA E transmembrane transport
CFCHMLLK_00080 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFCHMLLK_00081 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CFCHMLLK_00082 1e-262 argH 4.3.2.1 E Argininosuccinate lyase
CFCHMLLK_00083 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CFCHMLLK_00084 2.9e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFCHMLLK_00085 3.8e-185 jag S RNA-binding protein
CFCHMLLK_00086 1e-13 rpmH J Ribosomal protein L34
CFCHMLLK_00087 1.1e-83 L Transposase
CFCHMLLK_00088 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CFCHMLLK_00090 1.6e-131 cbiO P ABC transporter
CFCHMLLK_00091 1.7e-137 P cobalt transport protein
CFCHMLLK_00092 7.9e-177 cbiM P PDGLE domain
CFCHMLLK_00093 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CFCHMLLK_00094 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFCHMLLK_00095 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CFCHMLLK_00096 6.6e-78 ureE O enzyme active site formation
CFCHMLLK_00097 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CFCHMLLK_00098 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CFCHMLLK_00099 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CFCHMLLK_00100 6.8e-95 ureI S AmiS/UreI family transporter
CFCHMLLK_00101 3.5e-131 S Domain of unknown function (DUF4173)
CFCHMLLK_00102 1.9e-44 yhaI L Membrane
CFCHMLLK_00103 2.2e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CFCHMLLK_00104 1.8e-27 comA V protein secretion by the type I secretion system
CFCHMLLK_00105 1.1e-34 V protein secretion by the type I secretion system
CFCHMLLK_00106 1.6e-109 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CFCHMLLK_00107 1.9e-33 V protein secretion by the type I secretion system
CFCHMLLK_00108 1.5e-161 K sequence-specific DNA binding
CFCHMLLK_00109 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
CFCHMLLK_00110 3.2e-90 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CFCHMLLK_00111 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CFCHMLLK_00112 1.8e-248 trkA P Potassium transporter peripheral membrane component
CFCHMLLK_00113 3.5e-258 trkH P Cation transport protein
CFCHMLLK_00114 4.3e-42 yidD S Could be involved in insertion of integral membrane proteins into the membrane
CFCHMLLK_00115 4.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CFCHMLLK_00116 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFCHMLLK_00117 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFCHMLLK_00118 7.5e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
CFCHMLLK_00119 5.4e-86 ykuL S CBS domain
CFCHMLLK_00120 3.5e-99 XK27_09740 S Phosphoesterase
CFCHMLLK_00121 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFCHMLLK_00122 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CFCHMLLK_00123 7.6e-36 yneF S UPF0154 protein
CFCHMLLK_00124 9.6e-92 K transcriptional regulator
CFCHMLLK_00125 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CFCHMLLK_00128 8.8e-98 ybhL S Belongs to the BI1 family
CFCHMLLK_00129 2.3e-92 XK27_09705 6.1.1.14 S HD superfamily hydrolase
CFCHMLLK_00130 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFCHMLLK_00131 1.2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CFCHMLLK_00132 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFCHMLLK_00133 1e-84 L Integrase core domain protein
CFCHMLLK_00134 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CFCHMLLK_00135 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFCHMLLK_00136 1e-81 XK27_09675 K -acetyltransferase
CFCHMLLK_00137 1.5e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CFCHMLLK_00138 2.5e-23
CFCHMLLK_00139 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
CFCHMLLK_00140 2.2e-297 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
CFCHMLLK_00141 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CFCHMLLK_00142 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CFCHMLLK_00143 3.1e-95 ypsA S Belongs to the UPF0398 family
CFCHMLLK_00144 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CFCHMLLK_00145 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFCHMLLK_00146 1.7e-259 pepC 3.4.22.40 E aminopeptidase
CFCHMLLK_00147 3.2e-77 yhaI L Membrane
CFCHMLLK_00148 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CFCHMLLK_00149 5.3e-278 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFCHMLLK_00150 6e-140 S COG1073 Hydrolases of the alpha beta superfamily
CFCHMLLK_00151 1.7e-88 S thiolester hydrolase activity
CFCHMLLK_00152 7.6e-41 K transcriptional
CFCHMLLK_00153 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CFCHMLLK_00154 3.4e-135 glcR K transcriptional regulator (DeoR family)
CFCHMLLK_00155 1.1e-34 cof Q phosphatase activity
CFCHMLLK_00156 1.1e-53 cof Q phosphatase activity
CFCHMLLK_00157 1.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
CFCHMLLK_00158 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
CFCHMLLK_00159 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
CFCHMLLK_00160 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFCHMLLK_00161 6.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CFCHMLLK_00162 3.4e-55 S TM2 domain
CFCHMLLK_00163 4e-42
CFCHMLLK_00165 9.3e-77 yocD 3.4.17.13 V carboxypeptidase activity
CFCHMLLK_00166 9.2e-92 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CFCHMLLK_00168 6.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
CFCHMLLK_00169 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFCHMLLK_00170 1.1e-83 S Putative small multi-drug export protein
CFCHMLLK_00171 6.2e-76 ctsR K Belongs to the CtsR family
CFCHMLLK_00172 0.0 clpC O Belongs to the ClpA ClpB family
CFCHMLLK_00173 5.9e-126 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CFCHMLLK_00174 9.3e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CFCHMLLK_00175 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CFCHMLLK_00176 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CFCHMLLK_00177 2e-143 S SseB protein N-terminal domain
CFCHMLLK_00178 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
CFCHMLLK_00179 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CFCHMLLK_00180 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CFCHMLLK_00184 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFCHMLLK_00185 7e-92 yacP S RNA-binding protein containing a PIN domain
CFCHMLLK_00186 3.7e-154 degV S DegV family
CFCHMLLK_00187 3.2e-33 K helix-turn-helix
CFCHMLLK_00188 2.7e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CFCHMLLK_00189 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFCHMLLK_00190 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
CFCHMLLK_00191 4.1e-36 K sequence-specific DNA binding
CFCHMLLK_00193 6.8e-78 S Lantibiotic dehydratase, C terminus
CFCHMLLK_00194 0.0 S Lantibiotic dehydratase, C terminus
CFCHMLLK_00195 9.5e-231 spaC2 V Lanthionine synthetase C family protein
CFCHMLLK_00196 2.1e-72 EGP Major facilitator Superfamily
CFCHMLLK_00197 6.7e-90 EGP Major facilitator Superfamily
CFCHMLLK_00198 5.2e-126
CFCHMLLK_00200 1.9e-26 isp2 S pathogenesis
CFCHMLLK_00201 5.7e-91 tnp L Transposase
CFCHMLLK_00202 5.8e-155 capA M Bacterial capsule synthesis protein
CFCHMLLK_00203 3.7e-57 capA M Bacterial capsule synthesis protein
CFCHMLLK_00204 3.6e-39 gcvR T UPF0237 protein
CFCHMLLK_00205 1.7e-243 XK27_08635 S UPF0210 protein
CFCHMLLK_00206 1.7e-133 ais G Phosphoglycerate mutase
CFCHMLLK_00207 1.3e-140 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CFCHMLLK_00208 1.2e-100 acmA 3.2.1.17 NU amidase activity
CFCHMLLK_00209 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CFCHMLLK_00210 1.2e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFCHMLLK_00211 4.9e-297 dnaK O Heat shock 70 kDa protein
CFCHMLLK_00212 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CFCHMLLK_00213 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CFCHMLLK_00214 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
CFCHMLLK_00215 7.7e-61 hmpT S membrane
CFCHMLLK_00216 2.3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFCHMLLK_00217 3.4e-123 comFC S Competence protein
CFCHMLLK_00218 1.7e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CFCHMLLK_00219 2.4e-110 yvyE 3.4.13.9 S YigZ family
CFCHMLLK_00220 2.8e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CFCHMLLK_00221 7.7e-13 acuB S IMP dehydrogenase activity
CFCHMLLK_00222 2.5e-63 acuB S CBS domain
CFCHMLLK_00223 2.1e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
CFCHMLLK_00224 8.2e-137 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
CFCHMLLK_00225 1.6e-137 livM E Belongs to the binding-protein-dependent transport system permease family
CFCHMLLK_00226 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
CFCHMLLK_00227 5.3e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
CFCHMLLK_00228 7.1e-46 ylbG S UPF0298 protein
CFCHMLLK_00229 4.4e-74 ylbF S Belongs to the UPF0342 family
CFCHMLLK_00230 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CFCHMLLK_00231 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFCHMLLK_00232 1.4e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
CFCHMLLK_00233 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CFCHMLLK_00234 9.7e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
CFCHMLLK_00235 1e-81 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
CFCHMLLK_00236 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
CFCHMLLK_00237 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFCHMLLK_00238 4.8e-235 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
CFCHMLLK_00240 2.2e-24 yvdD 3.2.2.10 S cytokinin biosynthetic process
CFCHMLLK_00241 8.2e-21 yvdD 3.2.2.10 S cytokinin biosynthetic process
CFCHMLLK_00242 2e-09 yvdD 3.2.2.10 S Belongs to the LOG family
CFCHMLLK_00243 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFCHMLLK_00244 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFCHMLLK_00245 1.4e-41 ylxQ J ribosomal protein
CFCHMLLK_00246 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
CFCHMLLK_00247 4.1e-212 nusA K Participates in both transcription termination and antitermination
CFCHMLLK_00248 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
CFCHMLLK_00249 2.8e-219 brpA K Transcriptional
CFCHMLLK_00250 3.2e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
CFCHMLLK_00251 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
CFCHMLLK_00252 5.6e-248 pbuO S permease
CFCHMLLK_00253 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CFCHMLLK_00254 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
CFCHMLLK_00255 3.1e-181 manL 2.7.1.191 G pts system
CFCHMLLK_00256 7.8e-117 manM G pts system
CFCHMLLK_00257 5.6e-169 manN G PTS system mannose fructose sorbose family IID component
CFCHMLLK_00258 6.5e-63 manO S protein conserved in bacteria
CFCHMLLK_00259 6.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFCHMLLK_00260 4.2e-83 XK27_03610 K Gnat family
CFCHMLLK_00261 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CFCHMLLK_00262 2.4e-275 pepV 3.5.1.18 E Dipeptidase
CFCHMLLK_00263 1.5e-111 ung2 3.2.2.27 L Uracil-DNA glycosylase
CFCHMLLK_00264 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFCHMLLK_00265 1.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFCHMLLK_00266 9.5e-68 S Protein of unknown function (DUF1697)
CFCHMLLK_00267 1.2e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFCHMLLK_00268 1.3e-48 clcA_2 P chloride channel
CFCHMLLK_00269 3.8e-09 yfeJ 6.3.5.2 F glutamine amidotransferase
CFCHMLLK_00270 2.6e-77 yfeJ 6.3.5.2 F glutamine amidotransferase
CFCHMLLK_00271 1.3e-23 yfeJ 6.3.5.2 F glutamine amidotransferase
CFCHMLLK_00272 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
CFCHMLLK_00273 8.3e-255 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
CFCHMLLK_00274 3.6e-134 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
CFCHMLLK_00275 2.7e-102 cps4C M biosynthesis protein
CFCHMLLK_00276 1e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
CFCHMLLK_00277 2.9e-254 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
CFCHMLLK_00278 1.7e-45 rgpAc GT4 M Domain of unknown function (DUF1972)
CFCHMLLK_00279 8.7e-116 lspL 5.1.3.6 M epimerase dehydratase
CFCHMLLK_00280 7.8e-22 S Bacterial transferase hexapeptide (six repeats)
CFCHMLLK_00281 1.8e-12 S Bacterial transferase hexapeptide repeat protein
CFCHMLLK_00282 1e-09 S Bacterial transferase hexapeptide (six repeats)
CFCHMLLK_00283 2.4e-194 ugd 1.1.1.22 M UDP binding domain
CFCHMLLK_00284 1.4e-54 pssD M Oligosaccharide biosynthesis protein Alg14 like
CFCHMLLK_00285 2.5e-75 pssE S Glycosyltransferase family 28 C-terminal domain
CFCHMLLK_00286 6.7e-113 pssE GT4 M Glycosyltransferase family 28 C-terminal domain
CFCHMLLK_00287 3.6e-71 J Serine hydrolase involved in the detoxification of formaldehyde
CFCHMLLK_00288 1e-23 S Hexapeptide repeat of succinyl-transferase
CFCHMLLK_00289 2.6e-56 epsJ GT2 S Glycosyltransferase like family 2
CFCHMLLK_00290 2.7e-42 2.3.1.30 E serine acetyltransferase
CFCHMLLK_00291 3.7e-41 S Psort location CytoplasmicMembrane, score 9.99
CFCHMLLK_00292 1.4e-74 M Glycosyltransferase sugar-binding region containing DXD motif
CFCHMLLK_00293 1.6e-61 pglH 2.4.1.187, 2.4.1.292 GT26,GT4 M Glycosyl transferases group 1
CFCHMLLK_00294 6.2e-136 M Psort location CytoplasmicMembrane, score
CFCHMLLK_00296 2.2e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
CFCHMLLK_00297 4e-56 S ABC-2 type transporter
CFCHMLLK_00298 2e-95
CFCHMLLK_00299 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CFCHMLLK_00300 4e-167 dnaI L Primosomal protein DnaI
CFCHMLLK_00301 1.4e-217 dnaB L Replication initiation and membrane attachment
CFCHMLLK_00302 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFCHMLLK_00303 2.8e-282 T PhoQ Sensor
CFCHMLLK_00304 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFCHMLLK_00305 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
CFCHMLLK_00306 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
CFCHMLLK_00307 2.1e-244 P COG0168 Trk-type K transport systems, membrane components
CFCHMLLK_00308 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
CFCHMLLK_00309 2e-10 ulaG S L-ascorbate 6-phosphate lactonase
CFCHMLLK_00310 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFCHMLLK_00311 7.2e-147 cbiQ P cobalt transport
CFCHMLLK_00312 0.0 ykoD P abc transporter atp-binding protein
CFCHMLLK_00313 8e-94 S UPF0397 protein
CFCHMLLK_00314 1e-156 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
CFCHMLLK_00315 7.9e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CFCHMLLK_00316 3e-98 metI P ABC transporter (Permease
CFCHMLLK_00317 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFCHMLLK_00318 6.8e-22 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
CFCHMLLK_00319 8.3e-91 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
CFCHMLLK_00320 1.4e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
CFCHMLLK_00321 2.1e-163 metQ M Belongs to the NlpA lipoprotein family
CFCHMLLK_00322 8.4e-151 ET amino acid transport
CFCHMLLK_00324 1.6e-12 S Bacteriocin class II with double-glycine leader peptide
CFCHMLLK_00328 6e-40 L COG2963 Transposase and inactivated derivatives
CFCHMLLK_00329 1.4e-71 L Transposase and inactivated derivatives
CFCHMLLK_00331 4.1e-24
CFCHMLLK_00332 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CFCHMLLK_00333 7.7e-146 mesE M HlyD family secretion protein
CFCHMLLK_00335 4.5e-122 blpH 2.7.13.3 T GHKL domain
CFCHMLLK_00336 2e-103 blpR KT LytTr DNA-binding domain
CFCHMLLK_00337 3.3e-21 blpS KT phosphorelay signal transduction system
CFCHMLLK_00338 5.5e-20
CFCHMLLK_00339 1e-297 U relaxase
CFCHMLLK_00340 2.1e-50 S Bacterial mobilisation protein (MobC)
CFCHMLLK_00341 5.9e-53
CFCHMLLK_00342 8.6e-100
CFCHMLLK_00343 1.1e-124 K DNA-binding helix-turn-helix protein
CFCHMLLK_00345 2.6e-56 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFCHMLLK_00346 1.8e-195 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFCHMLLK_00347 1.8e-57
CFCHMLLK_00348 1.2e-43
CFCHMLLK_00349 8e-37
CFCHMLLK_00350 3.3e-49
CFCHMLLK_00351 1.5e-17
CFCHMLLK_00352 3.8e-196 L Protein of unknown function (DUF3991)
CFCHMLLK_00353 9.3e-102
CFCHMLLK_00354 3.5e-113 S ABC-2 family transporter protein
CFCHMLLK_00355 3.7e-111 prrC V abc transporter atp-binding protein
CFCHMLLK_00357 1.7e-59 yydH S Peptidase M50
CFCHMLLK_00358 2.7e-126 S Radical SAM superfamily
CFCHMLLK_00360 1.1e-87 adk 2.7.4.3 F topology modulation protein
CFCHMLLK_00361 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFCHMLLK_00362 1.8e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFCHMLLK_00363 1.7e-35 XK27_09805 S MORN repeat protein
CFCHMLLK_00364 0.0 XK27_09800 I Acyltransferase
CFCHMLLK_00365 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CFCHMLLK_00366 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
CFCHMLLK_00367 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFCHMLLK_00368 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
CFCHMLLK_00369 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CFCHMLLK_00370 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFCHMLLK_00371 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFCHMLLK_00372 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFCHMLLK_00373 1e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFCHMLLK_00374 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFCHMLLK_00375 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
CFCHMLLK_00376 2e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFCHMLLK_00377 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFCHMLLK_00378 1.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFCHMLLK_00379 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFCHMLLK_00380 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFCHMLLK_00381 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFCHMLLK_00382 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFCHMLLK_00383 1.1e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFCHMLLK_00384 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFCHMLLK_00385 2.5e-23 rpmD J ribosomal protein l30
CFCHMLLK_00386 4.4e-58 rplO J binds to the 23S rRNA
CFCHMLLK_00387 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CFCHMLLK_00388 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CFCHMLLK_00389 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CFCHMLLK_00390 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CFCHMLLK_00391 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CFCHMLLK_00392 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CFCHMLLK_00393 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFCHMLLK_00394 3.3e-62 rplQ J ribosomal protein l17
CFCHMLLK_00395 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CFCHMLLK_00396 4.9e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CFCHMLLK_00397 4e-153 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFCHMLLK_00398 1.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
CFCHMLLK_00399 1.5e-103 yjbK S Adenylate cyclase
CFCHMLLK_00400 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFCHMLLK_00401 3.2e-206 iscS 2.8.1.7 E Cysteine desulfurase
CFCHMLLK_00402 3.1e-59 XK27_04120 S Putative amino acid metabolism
CFCHMLLK_00403 6.3e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CFCHMLLK_00404 2.3e-130 puuD T peptidase C26
CFCHMLLK_00405 6.2e-120 radC E Belongs to the UPF0758 family
CFCHMLLK_00406 6.4e-272 rgpF M Rhamnan synthesis protein F
CFCHMLLK_00407 9e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CFCHMLLK_00408 6.4e-140 rgpC GM Transport permease protein
CFCHMLLK_00409 5.3e-170 rgpB GT2 M Glycosyltransferase, group 2 family protein
CFCHMLLK_00410 1.1e-222 rgpA GT4 M Domain of unknown function (DUF1972)
CFCHMLLK_00411 5e-174 S Glucosyl transferase GtrII
CFCHMLLK_00412 1.8e-28 S Glucosyl transferase GtrII
CFCHMLLK_00413 1.6e-219 GT4 M transferase activity, transferring glycosyl groups
CFCHMLLK_00414 2e-217 M Psort location CytoplasmicMembrane, score
CFCHMLLK_00415 0.0 rgpF GT2,GT4 M Glycosyltransferase like family 2
CFCHMLLK_00416 5.9e-151 2.4.1.60 S Glycosyltransferase group 2 family protein
CFCHMLLK_00417 4.6e-42 S Uncharacterized conserved protein (DUF2304)
CFCHMLLK_00418 4.5e-129 arnC M group 2 family protein
CFCHMLLK_00419 1.1e-181 cpsIaJ S Glycosyltransferase like family 2
CFCHMLLK_00420 1e-184 S Glycosyltransferase like family 2
CFCHMLLK_00421 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
CFCHMLLK_00422 1.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CFCHMLLK_00423 2.9e-235 S Predicted membrane protein (DUF2142)
CFCHMLLK_00424 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
CFCHMLLK_00425 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
CFCHMLLK_00426 8e-202 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CFCHMLLK_00427 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CFCHMLLK_00428 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CFCHMLLK_00429 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
CFCHMLLK_00430 2e-200 arcT 2.6.1.1 E Aminotransferase
CFCHMLLK_00431 1.5e-136 ET ABC transporter
CFCHMLLK_00432 2.8e-143 ET Belongs to the bacterial solute-binding protein 3 family
CFCHMLLK_00433 2.9e-84 mutT 3.6.1.55 F Nudix family
CFCHMLLK_00434 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CFCHMLLK_00436 3.8e-77 S CAAX amino terminal protease family protein
CFCHMLLK_00437 7.6e-32 S CAAX amino terminal protease family protein
CFCHMLLK_00438 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
CFCHMLLK_00439 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
CFCHMLLK_00440 1.1e-16 XK27_00735
CFCHMLLK_00441 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFCHMLLK_00443 1.4e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CFCHMLLK_00446 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
CFCHMLLK_00447 3e-37 ycaO O OsmC-like protein
CFCHMLLK_00448 6.5e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
CFCHMLLK_00450 1.3e-109 csn2 S CRISPR-associated protein (Cas_Csn2)
CFCHMLLK_00451 2.2e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CFCHMLLK_00452 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CFCHMLLK_00453 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CFCHMLLK_00454 2e-115 serB 3.1.3.3 E phosphoserine phosphatase
CFCHMLLK_00455 2.1e-305 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CFCHMLLK_00456 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFCHMLLK_00457 2.6e-109 3.1.3.18 S IA, variant 1
CFCHMLLK_00458 2.2e-117 lrgB M effector of murein hydrolase
CFCHMLLK_00459 4.5e-56 lrgA S Effector of murein hydrolase LrgA
CFCHMLLK_00461 1.9e-59 arsC 1.20.4.1 P Belongs to the ArsC family
CFCHMLLK_00462 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFCHMLLK_00463 5.1e-104 wecD M Acetyltransferase (GNAT) domain
CFCHMLLK_00464 1.5e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFCHMLLK_00465 4.1e-116 GK ROK family
CFCHMLLK_00466 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
CFCHMLLK_00467 1.5e-111 XK27_08050 O HflC and HflK could regulate a protease
CFCHMLLK_00469 2.3e-206 potD P spermidine putrescine ABC transporter
CFCHMLLK_00470 9.5e-133 potC P ABC-type spermidine putrescine transport system, permease component II
CFCHMLLK_00471 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
CFCHMLLK_00472 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CFCHMLLK_00473 4.6e-171 murB 1.3.1.98 M cell wall formation
CFCHMLLK_00474 7.2e-86 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFCHMLLK_00475 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFCHMLLK_00476 1.3e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
CFCHMLLK_00477 2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFCHMLLK_00478 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
CFCHMLLK_00479 0.0 ydaO E amino acid
CFCHMLLK_00480 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CFCHMLLK_00481 4.1e-37 ylqC L Belongs to the UPF0109 family
CFCHMLLK_00482 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CFCHMLLK_00483 2.7e-108 tehB 2.1.1.265 PQ tellurite resistance protein tehb
CFCHMLLK_00484 1e-156 xth 3.1.11.2 L exodeoxyribonuclease III
CFCHMLLK_00485 2.1e-74 S QueT transporter
CFCHMLLK_00486 6.4e-119 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
CFCHMLLK_00487 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CFCHMLLK_00488 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFCHMLLK_00489 1.3e-85 ccl S cog cog4708
CFCHMLLK_00490 7.4e-164 rbn E Belongs to the UPF0761 family
CFCHMLLK_00491 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
CFCHMLLK_00492 1.9e-231 ytoI K transcriptional regulator containing CBS domains
CFCHMLLK_00493 1.8e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
CFCHMLLK_00494 3.1e-234 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFCHMLLK_00495 0.0 comEC S Competence protein ComEC
CFCHMLLK_00496 1.2e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
CFCHMLLK_00497 1.3e-142 plsC 2.3.1.51 I Acyltransferase
CFCHMLLK_00498 6.4e-80 nodB3 G polysaccharide deacetylase
CFCHMLLK_00499 8e-42 nodB3 G polysaccharide deacetylase
CFCHMLLK_00500 4.1e-181 L Transposase
CFCHMLLK_00501 2.9e-27 L Transposase
CFCHMLLK_00502 1.2e-137 yabB 2.1.1.223 L Methyltransferase
CFCHMLLK_00503 3e-41 yazA L endonuclease containing a URI domain
CFCHMLLK_00504 4.6e-251 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CFCHMLLK_00505 2.3e-154 corA P CorA-like protein
CFCHMLLK_00506 1.9e-62 yjqA S Bacterial PH domain
CFCHMLLK_00507 7.8e-100 thiT S Thiamine transporter
CFCHMLLK_00508 9.5e-158 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CFCHMLLK_00509 6.8e-199 yjbB G Permeases of the major facilitator superfamily
CFCHMLLK_00510 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFCHMLLK_00511 1.1e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
CFCHMLLK_00512 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CFCHMLLK_00516 1.1e-155 cjaA ET ABC transporter substrate-binding protein
CFCHMLLK_00517 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
CFCHMLLK_00518 3.5e-115 P ABC transporter (Permease
CFCHMLLK_00519 5.1e-114 papP P ABC transporter (Permease
CFCHMLLK_00520 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CFCHMLLK_00521 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
CFCHMLLK_00522 0.0 copA 3.6.3.54 P P-type ATPase
CFCHMLLK_00523 1.6e-73 copY K Copper transport repressor, CopY TcrY family
CFCHMLLK_00524 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CFCHMLLK_00525 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CFCHMLLK_00526 1.2e-100 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
CFCHMLLK_00527 4.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CFCHMLLK_00528 9.6e-178 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CFCHMLLK_00529 4.7e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
CFCHMLLK_00530 7.4e-258 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFCHMLLK_00531 1.4e-41 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
CFCHMLLK_00532 3.2e-56
CFCHMLLK_00533 0.0 ctpE P E1-E2 ATPase
CFCHMLLK_00534 4.3e-29
CFCHMLLK_00535 2.2e-10
CFCHMLLK_00536 5.5e-17 S Plasmid replication protein
CFCHMLLK_00540 1.1e-128 S Protein conserved in bacteria
CFCHMLLK_00541 3.9e-09 KLT Protein tyrosine kinase
CFCHMLLK_00542 1.3e-31 S Hypothetical protein (DUF2513)
CFCHMLLK_00543 1.1e-25
CFCHMLLK_00545 1.3e-216 S MvaI/BcnI restriction endonuclease family
CFCHMLLK_00547 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
CFCHMLLK_00548 7.8e-110 K Peptidase S24-like
CFCHMLLK_00549 1.1e-126 E IrrE N-terminal-like domain
CFCHMLLK_00550 3e-19 S Domain of unknown function (DUF3173)
CFCHMLLK_00551 1.1e-171 L Belongs to the 'phage' integrase family
CFCHMLLK_00552 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFCHMLLK_00553 5.1e-47 L transposase activity
CFCHMLLK_00554 9.9e-56 K transcriptional regulator, MerR family
CFCHMLLK_00555 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
CFCHMLLK_00556 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
CFCHMLLK_00557 1.1e-62 XK27_02560 S cog cog2151
CFCHMLLK_00558 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CFCHMLLK_00559 7.7e-227 ytfP S Flavoprotein
CFCHMLLK_00561 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CFCHMLLK_00562 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
CFCHMLLK_00563 2.7e-183 ecsB U ABC transporter
CFCHMLLK_00564 1.5e-132 ecsA V abc transporter atp-binding protein
CFCHMLLK_00565 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CFCHMLLK_00566 1.3e-11
CFCHMLLK_00567 5.1e-12 S CD20-like family
CFCHMLLK_00568 7.3e-107
CFCHMLLK_00569 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
CFCHMLLK_00570 1e-204 ylbM S Belongs to the UPF0348 family
CFCHMLLK_00571 2e-140 yqeM Q Methyltransferase domain protein
CFCHMLLK_00572 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CFCHMLLK_00573 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CFCHMLLK_00574 1.7e-116 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFCHMLLK_00575 3.5e-49 yhbY J RNA-binding protein
CFCHMLLK_00576 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CFCHMLLK_00577 1.8e-98 yqeG S hydrolase of the HAD superfamily
CFCHMLLK_00578 6.7e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CFCHMLLK_00579 1.4e-65
CFCHMLLK_00580 3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFCHMLLK_00581 3.1e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CFCHMLLK_00582 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFCHMLLK_00583 2.2e-24 2.4.1.52 GT4 M transferase activity, transferring glycosyl groups
CFCHMLLK_00584 5.3e-30 M lipopolysaccharide 3-alpha-galactosyltransferase activity
CFCHMLLK_00585 1.7e-226 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFCHMLLK_00586 1.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFCHMLLK_00587 2.1e-154 hlpA M Belongs to the NlpA lipoprotein family
CFCHMLLK_00588 6.8e-101 pncA Q isochorismatase
CFCHMLLK_00589 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CFCHMLLK_00590 1.1e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
CFCHMLLK_00591 2.4e-75 XK27_03180 T universal stress protein
CFCHMLLK_00593 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFCHMLLK_00594 9.9e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
CFCHMLLK_00595 7e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
CFCHMLLK_00596 0.0 yjcE P NhaP-type Na H and K H antiporters
CFCHMLLK_00598 2.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
CFCHMLLK_00599 8.4e-184 yhcC S radical SAM protein
CFCHMLLK_00600 8.4e-196 ylbL T Belongs to the peptidase S16 family
CFCHMLLK_00601 2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFCHMLLK_00602 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
CFCHMLLK_00603 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CFCHMLLK_00604 1.9e-09 S Protein of unknown function (DUF4059)
CFCHMLLK_00605 3.4e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
CFCHMLLK_00606 2.2e-171 yxeN P ABC transporter (Permease
CFCHMLLK_00607 8.8e-153 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CFCHMLLK_00609 2e-205 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFCHMLLK_00610 0.0 pflB 2.3.1.54 C formate acetyltransferase'
CFCHMLLK_00611 3.4e-146 cah 4.2.1.1 P carbonic anhydrase
CFCHMLLK_00612 1e-84 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFCHMLLK_00613 7.2e-46 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
CFCHMLLK_00614 1.4e-81 D nuclear chromosome segregation
CFCHMLLK_00615 5.4e-22 L Phage integrase family
CFCHMLLK_00616 1.6e-123 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
CFCHMLLK_00617 4.4e-127 ybbM S transport system, permease component
CFCHMLLK_00618 6.8e-116 ybbL S abc transporter atp-binding protein
CFCHMLLK_00619 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
CFCHMLLK_00620 4.6e-140 cppA E CppA N-terminal
CFCHMLLK_00621 9.1e-30 V CAAX protease self-immunity
CFCHMLLK_00622 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
CFCHMLLK_00623 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CFCHMLLK_00626 2.6e-137 blpT
CFCHMLLK_00638 5.3e-11
CFCHMLLK_00644 2.1e-138 mreC M Involved in formation and maintenance of cell shape
CFCHMLLK_00645 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CFCHMLLK_00646 3.5e-93 usp 3.5.1.28 CBM50 S CHAP domain
CFCHMLLK_00647 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFCHMLLK_00648 8e-25
CFCHMLLK_00649 2.9e-218 araT 2.6.1.1 E Aminotransferase
CFCHMLLK_00650 7e-144 recO L Involved in DNA repair and RecF pathway recombination
CFCHMLLK_00651 2.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CFCHMLLK_00652 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFCHMLLK_00653 2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CFCHMLLK_00654 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFCHMLLK_00655 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFCHMLLK_00656 1.4e-184 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CFCHMLLK_00657 5.2e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFCHMLLK_00658 1.4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CFCHMLLK_00659 3.2e-53 bta 1.8.1.8 CO cell redox homeostasis
CFCHMLLK_00660 9.1e-10 L thioesterase
CFCHMLLK_00661 7.8e-143 S Macro domain protein
CFCHMLLK_00662 4.8e-51 trxA O Belongs to the thioredoxin family
CFCHMLLK_00663 1.5e-74 yccU S CoA-binding protein
CFCHMLLK_00664 4.1e-144 tatD L Hydrolase, tatd
CFCHMLLK_00665 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CFCHMLLK_00666 5.8e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CFCHMLLK_00668 9.9e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CFCHMLLK_00669 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CFCHMLLK_00670 2.4e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
CFCHMLLK_00671 1.5e-172 rmuC S RmuC domain protein
CFCHMLLK_00672 1.8e-178 cbf S 3'-5' exoribonuclease yhaM
CFCHMLLK_00673 2.4e-142 purR 2.4.2.7 F operon repressor
CFCHMLLK_00674 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFCHMLLK_00675 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CFCHMLLK_00676 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFCHMLLK_00677 2.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CFCHMLLK_00678 2.9e-87 L Integrase core domain protein
CFCHMLLK_00679 3.5e-55 L transposition
CFCHMLLK_00680 5.7e-23 L Transposase
CFCHMLLK_00681 1.1e-43 L transposase activity
CFCHMLLK_00682 3.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CFCHMLLK_00683 1.6e-126 T PhoQ Sensor
CFCHMLLK_00684 2.8e-40 T PhoQ Sensor
CFCHMLLK_00685 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFCHMLLK_00686 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CFCHMLLK_00687 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
CFCHMLLK_00688 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFCHMLLK_00689 1.4e-93 panT S ECF transporter, substrate-specific component
CFCHMLLK_00690 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CFCHMLLK_00691 7.3e-166 metF 1.5.1.20 C reductase
CFCHMLLK_00692 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFCHMLLK_00694 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
CFCHMLLK_00695 0.0 3.6.3.8 P cation transport ATPase
CFCHMLLK_00696 2.1e-30 rpsT J rRNA binding
CFCHMLLK_00697 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
CFCHMLLK_00698 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
CFCHMLLK_00699 6.9e-26 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
CFCHMLLK_00700 1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
CFCHMLLK_00701 2.1e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
CFCHMLLK_00702 1.2e-62 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFCHMLLK_00703 2.9e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CFCHMLLK_00704 3.1e-190 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CFCHMLLK_00705 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CFCHMLLK_00706 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
CFCHMLLK_00707 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
CFCHMLLK_00708 4e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CFCHMLLK_00709 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CFCHMLLK_00710 6.8e-81 ypmB S Protein conserved in bacteria
CFCHMLLK_00711 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CFCHMLLK_00712 1.3e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CFCHMLLK_00714 8.1e-08
CFCHMLLK_00715 9.4e-43 K Cold-Shock Protein
CFCHMLLK_00716 1e-30 cspD K Cold shock protein domain
CFCHMLLK_00717 7.9e-41 pepD E dipeptidase activity
CFCHMLLK_00718 1.4e-91 pepD E Dipeptidase
CFCHMLLK_00719 8.7e-162 whiA K May be required for sporulation
CFCHMLLK_00720 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CFCHMLLK_00721 1.2e-163 rapZ S Displays ATPase and GTPase activities
CFCHMLLK_00722 7.4e-138 yejC S cyclic nucleotide-binding protein
CFCHMLLK_00723 7.7e-20 D nuclear chromosome segregation
CFCHMLLK_00724 7.2e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
CFCHMLLK_00725 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CFCHMLLK_00726 5.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
CFCHMLLK_00727 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFCHMLLK_00728 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
CFCHMLLK_00730 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFCHMLLK_00731 8.6e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CFCHMLLK_00732 5.5e-36 XK27_02060 S Transglycosylase associated protein
CFCHMLLK_00733 1.8e-26 badR K DNA-binding transcription factor activity
CFCHMLLK_00734 1.1e-95 S reductase
CFCHMLLK_00735 1.3e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
CFCHMLLK_00736 1.9e-107 S Domain of unknown function (DUF1803)
CFCHMLLK_00737 7.8e-102 ygaC J Belongs to the UPF0374 family
CFCHMLLK_00738 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
CFCHMLLK_00739 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFCHMLLK_00740 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
CFCHMLLK_00741 1.4e-195 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CFCHMLLK_00742 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CFCHMLLK_00743 2e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CFCHMLLK_00744 4.5e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
CFCHMLLK_00745 9.9e-19 S Domain of unknown function (DUF4649)
CFCHMLLK_00746 1.8e-158 L Transposase
CFCHMLLK_00747 5.7e-294 amiA E ABC transporter, substrate-binding protein, family 5
CFCHMLLK_00748 1.2e-47 blpT
CFCHMLLK_00749 1.1e-76 S CAAX protease self-immunity
CFCHMLLK_00751 3.6e-19 K Psort location Cytoplasmic, score
CFCHMLLK_00752 0.0 L Recombinase
CFCHMLLK_00753 2.4e-105
CFCHMLLK_00754 3.9e-31 K Cro/C1-type HTH DNA-binding domain
CFCHMLLK_00755 1.2e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
CFCHMLLK_00756 1.2e-27 estA E GDSL-like Lipase/Acylhydrolase
CFCHMLLK_00757 1.3e-97
CFCHMLLK_00758 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CFCHMLLK_00759 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CFCHMLLK_00760 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CFCHMLLK_00761 4.2e-184 S CRISPR-associated protein Csn2 subfamily St
CFCHMLLK_00762 2.1e-146 ycgQ S TIGR03943 family
CFCHMLLK_00763 5.1e-154 XK27_03015 S permease
CFCHMLLK_00765 0.0 yhgF K Transcriptional accessory protein
CFCHMLLK_00766 4.9e-86 ydcK S Belongs to the SprT family
CFCHMLLK_00767 2.9e-41 pspC KT PspC domain
CFCHMLLK_00768 3.4e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFCHMLLK_00769 3.1e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFCHMLLK_00771 2.2e-62 ytxH S General stress protein
CFCHMLLK_00773 2e-177 yegQ O Peptidase U32
CFCHMLLK_00774 3.4e-252 yegQ O Peptidase U32
CFCHMLLK_00775 4.2e-87 bioY S biotin synthase
CFCHMLLK_00777 1.1e-33 XK27_12190 S protein conserved in bacteria
CFCHMLLK_00778 9.6e-234 mntH P H( )-stimulated, divalent metal cation uptake system
CFCHMLLK_00779 1.7e-08
CFCHMLLK_00780 7e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
CFCHMLLK_00781 1.5e-100 L helicase
CFCHMLLK_00782 6e-308 L helicase
CFCHMLLK_00783 5.8e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CFCHMLLK_00784 8.5e-151 M LysM domain
CFCHMLLK_00785 7.7e-09
CFCHMLLK_00786 2.3e-175 S hydrolase
CFCHMLLK_00787 1.5e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
CFCHMLLK_00788 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFCHMLLK_00789 1.6e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
CFCHMLLK_00790 2.7e-27 P Hemerythrin HHE cation binding domain protein
CFCHMLLK_00791 2.6e-112 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFCHMLLK_00792 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
CFCHMLLK_00793 2.1e-23 MA20_36090 S Protein of unknown function (DUF2974)
CFCHMLLK_00794 1.4e-16 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CFCHMLLK_00795 2.6e-95 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CFCHMLLK_00796 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
CFCHMLLK_00797 1.3e-269 hsdM 2.1.1.72 V type I restriction-modification system
CFCHMLLK_00798 3.6e-99 hsdS 3.1.21.3 V COG0732 Restriction endonuclease S subunits
CFCHMLLK_00799 8.5e-45
CFCHMLLK_00800 3e-38
CFCHMLLK_00801 2e-175 spd F DNA RNA non-specific endonuclease
CFCHMLLK_00802 1.5e-92 lemA S LemA family
CFCHMLLK_00803 1.8e-135 htpX O Belongs to the peptidase M48B family
CFCHMLLK_00804 7.2e-75 S Psort location CytoplasmicMembrane, score
CFCHMLLK_00805 1.1e-55 S Domain of unknown function (DUF4430)
CFCHMLLK_00806 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CFCHMLLK_00807 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
CFCHMLLK_00808 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
CFCHMLLK_00809 3.9e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
CFCHMLLK_00810 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
CFCHMLLK_00811 4.6e-91 dps P Belongs to the Dps family
CFCHMLLK_00812 1.1e-80 perR P Belongs to the Fur family
CFCHMLLK_00813 8.4e-28 yqgQ S protein conserved in bacteria
CFCHMLLK_00814 2.2e-179 glk 2.7.1.2 G Glucokinase
CFCHMLLK_00815 0.0 typA T GTP-binding protein TypA
CFCHMLLK_00817 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFCHMLLK_00818 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFCHMLLK_00819 2.2e-178 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CFCHMLLK_00820 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CFCHMLLK_00821 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFCHMLLK_00822 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFCHMLLK_00823 1.5e-95 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CFCHMLLK_00824 8.8e-35 yggT D integral membrane protein
CFCHMLLK_00825 5.2e-142 ylmH T S4 RNA-binding domain
CFCHMLLK_00826 7.9e-136 divIVA D Cell division protein DivIVA
CFCHMLLK_00827 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFCHMLLK_00828 1.7e-46 L Transposase
CFCHMLLK_00829 8.4e-10
CFCHMLLK_00830 4.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
CFCHMLLK_00831 2e-45 rpmE2 J 50S ribosomal protein L31
CFCHMLLK_00832 1.3e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CFCHMLLK_00833 1.5e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
CFCHMLLK_00834 2e-154 gst O Glutathione S-transferase
CFCHMLLK_00835 1.3e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFCHMLLK_00836 9.3e-112 tdk 2.7.1.21 F thymidine kinase
CFCHMLLK_00837 6.6e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFCHMLLK_00838 3e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CFCHMLLK_00839 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CFCHMLLK_00840 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFCHMLLK_00841 6e-177 ndpA S 37-kD nucleoid-associated bacterial protein
CFCHMLLK_00842 1.9e-98 pvaA M lytic transglycosylase activity
CFCHMLLK_00843 0.0 yfiB1 V abc transporter atp-binding protein
CFCHMLLK_00844 0.0 XK27_10035 V abc transporter atp-binding protein
CFCHMLLK_00845 9.3e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFCHMLLK_00846 4.6e-238 dltB M Membrane protein involved in D-alanine export
CFCHMLLK_00847 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFCHMLLK_00848 8e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CFCHMLLK_00849 2.7e-32 L Integrase core domain protein
CFCHMLLK_00850 9.6e-32 L transposition
CFCHMLLK_00851 4.2e-29 L transposition
CFCHMLLK_00852 1.4e-87 L Transposase
CFCHMLLK_00853 7.1e-152 L Transposase
CFCHMLLK_00854 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFCHMLLK_00855 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CFCHMLLK_00856 5.5e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CFCHMLLK_00857 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
CFCHMLLK_00859 7.9e-61 divIC D Septum formation initiator
CFCHMLLK_00860 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CFCHMLLK_00861 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFCHMLLK_00862 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CFCHMLLK_00863 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CFCHMLLK_00864 1.1e-29 yyzM S Protein conserved in bacteria
CFCHMLLK_00865 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CFCHMLLK_00866 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFCHMLLK_00867 1.4e-133 parB K Belongs to the ParB family
CFCHMLLK_00868 7.3e-196 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
CFCHMLLK_00869 1.2e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFCHMLLK_00870 1.1e-119 yoaK S Psort location CytoplasmicMembrane, score
CFCHMLLK_00874 0.0 XK27_10405 S Bacterial membrane protein YfhO
CFCHMLLK_00875 6.7e-306 ybiT S abc transporter atp-binding protein
CFCHMLLK_00876 4.2e-153 yvjA S membrane
CFCHMLLK_00877 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CFCHMLLK_00878 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CFCHMLLK_00879 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFCHMLLK_00880 1.6e-45 yaaA S S4 domain protein YaaA
CFCHMLLK_00881 4.5e-233 ymfF S Peptidase M16
CFCHMLLK_00882 5.9e-241 ymfH S Peptidase M16
CFCHMLLK_00883 3.7e-138 ymfM S sequence-specific DNA binding
CFCHMLLK_00884 6.9e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFCHMLLK_00885 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFCHMLLK_00886 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFCHMLLK_00887 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFCHMLLK_00888 3.1e-93 lytE M LysM domain protein
CFCHMLLK_00889 5e-61 isaA GH23 M Immunodominant staphylococcal antigen A
CFCHMLLK_00890 0.0 S Bacterial membrane protein, YfhO
CFCHMLLK_00891 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CFCHMLLK_00892 1.5e-77 F NUDIX domain
CFCHMLLK_00893 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CFCHMLLK_00894 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CFCHMLLK_00895 2e-69 rplI J binds to the 23S rRNA
CFCHMLLK_00896 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CFCHMLLK_00897 3.1e-47 veg S Biofilm formation stimulator VEG
CFCHMLLK_00898 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFCHMLLK_00899 1.8e-08
CFCHMLLK_00900 3.3e-51 ypaA S membrane
CFCHMLLK_00901 6.4e-96 XK27_06935 K transcriptional regulator
CFCHMLLK_00902 3.6e-159 XK27_06930 V domain protein
CFCHMLLK_00903 2.7e-112 S Putative adhesin
CFCHMLLK_00904 8.1e-20 XK27_06920 S Protein of unknown function (DUF1700)
CFCHMLLK_00906 1.5e-47 K transcriptional regulator, PadR family
CFCHMLLK_00907 3.4e-13 nudL L hydrolase
CFCHMLLK_00908 9.2e-98 nudL L hydrolase
CFCHMLLK_00909 4.9e-12 K CsbD-like
CFCHMLLK_00910 7.4e-71 M Protein conserved in bacteria
CFCHMLLK_00911 1.8e-23 S Small integral membrane protein
CFCHMLLK_00912 3.5e-100
CFCHMLLK_00913 3.7e-27 S Membrane
CFCHMLLK_00915 8.5e-97 S Hydrophobic domain protein
CFCHMLLK_00916 2.4e-50 yegS 2.7.1.107 I lipid kinase activity
CFCHMLLK_00917 1.2e-48 yegS 2.7.1.107 I Diacylglycerol kinase
CFCHMLLK_00920 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CFCHMLLK_00921 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CFCHMLLK_00922 1.5e-29 metE 2.1.1.14 E Methionine synthase
CFCHMLLK_00923 5.6e-135 metE 2.1.1.14 E Methionine synthase
CFCHMLLK_00924 1.2e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
CFCHMLLK_00926 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CFCHMLLK_00927 1e-165 XK27_01785 S cog cog1284
CFCHMLLK_00928 7.7e-146 yaaA S Belongs to the UPF0246 family
CFCHMLLK_00929 2.8e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFCHMLLK_00930 3.4e-91 XK27_10930 K acetyltransferase
CFCHMLLK_00931 7.5e-14
CFCHMLLK_00932 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CFCHMLLK_00933 1.3e-296 ccs S the current gene model (or a revised gene model) may contain a frame shift
CFCHMLLK_00934 1.3e-45 yrzB S Belongs to the UPF0473 family
CFCHMLLK_00935 9.5e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFCHMLLK_00936 2.2e-44 yrzL S Belongs to the UPF0297 family
CFCHMLLK_00937 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CFCHMLLK_00938 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
CFCHMLLK_00940 3.8e-215 int L Belongs to the 'phage' integrase family
CFCHMLLK_00941 1.9e-18 S Domain of unknown function (DUF3173)
CFCHMLLK_00942 2.9e-155 L Replication initiation factor
CFCHMLLK_00943 3.9e-287 V ABC transporter transmembrane region
CFCHMLLK_00944 3e-104 C Radical SAM
CFCHMLLK_00945 2.6e-109 C Radical SAM
CFCHMLLK_00947 8.3e-128 Z012_04635 K sequence-specific DNA binding
CFCHMLLK_00948 2.4e-13 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CFCHMLLK_00949 2.1e-280 V ABC transporter
CFCHMLLK_00950 0.0 KLT serine threonine protein kinase
CFCHMLLK_00951 3.4e-155 Z012_04635 K sequence-specific DNA binding
CFCHMLLK_00953 2.5e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
CFCHMLLK_00954 1.1e-16 6.3.2.2 H gamma-glutamylcysteine synthetase
CFCHMLLK_00955 2.1e-111 6.3.2.2 H ergothioneine biosynthetic process
CFCHMLLK_00957 1.1e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
CFCHMLLK_00958 6.9e-22 tatD L hydrolase, TatD family'
CFCHMLLK_00959 2.8e-216 oxlT P COG0477 Permeases of the major facilitator superfamily
CFCHMLLK_00960 2.5e-35 L PFAM Integrase catalytic region
CFCHMLLK_00963 0.0 copB 3.6.3.4 P P-type ATPase
CFCHMLLK_00964 3.4e-98 L Transposase and inactivated derivatives
CFCHMLLK_00965 7.1e-108 nptA P sodium-dependent phosphate transmembrane transporter activity
CFCHMLLK_00966 4.1e-18 nptA P sodium-dependent phosphate transmembrane transporter activity
CFCHMLLK_00967 6.8e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFCHMLLK_00968 1.5e-52
CFCHMLLK_00969 4.4e-26
CFCHMLLK_00970 7.1e-62
CFCHMLLK_00971 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CFCHMLLK_00972 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CFCHMLLK_00973 4.5e-39 ynzC S UPF0291 protein
CFCHMLLK_00974 8.7e-254 cycA E permease
CFCHMLLK_00975 1.9e-09 uvrX 2.7.7.7 L impB/mucB/samB family
CFCHMLLK_00976 9.1e-23 pts33BCA G pts system
CFCHMLLK_00977 2e-40 pts33BCA G pts system
CFCHMLLK_00978 2.9e-21 pts33BCA G pts system
CFCHMLLK_00979 1.5e-95 pts33BCA G pts system
CFCHMLLK_00980 4.9e-49 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
CFCHMLLK_00981 1.7e-139 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFCHMLLK_00986 1.4e-167 fhuR K transcriptional regulator (lysR family)
CFCHMLLK_00987 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFCHMLLK_00988 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CFCHMLLK_00989 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFCHMLLK_00990 4.9e-227 pyrP F uracil Permease
CFCHMLLK_00991 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CFCHMLLK_00992 1.6e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
CFCHMLLK_00993 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
CFCHMLLK_00994 1.4e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
CFCHMLLK_00995 3.8e-20 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFCHMLLK_00996 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFCHMLLK_00997 4.8e-38 V permease protein
CFCHMLLK_00998 3.7e-35 V permease protein
CFCHMLLK_00999 1.1e-34 V efflux transmembrane transporter activity
CFCHMLLK_01000 1.5e-24 ytrF V efflux transmembrane transporter activity
CFCHMLLK_01001 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFCHMLLK_01002 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CFCHMLLK_01004 0.0 mdlB V abc transporter atp-binding protein
CFCHMLLK_01005 0.0 lmrA V abc transporter atp-binding protein
CFCHMLLK_01006 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFCHMLLK_01007 2.3e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CFCHMLLK_01008 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
CFCHMLLK_01009 1.9e-132 rr02 KT response regulator
CFCHMLLK_01010 3.8e-240 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CFCHMLLK_01011 2.8e-168 V ABC transporter
CFCHMLLK_01012 5.4e-122 sagI S ABC-2 type transporter
CFCHMLLK_01013 6.9e-197 yceA S Belongs to the UPF0176 family
CFCHMLLK_01014 1e-27 XK27_00085 K Transcriptional
CFCHMLLK_01015 3.7e-21
CFCHMLLK_01016 2.1e-140 deoD_1 2.4.2.3 F Phosphorylase superfamily
CFCHMLLK_01017 2.5e-113 S VIT family
CFCHMLLK_01018 1.1e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CFCHMLLK_01019 5.2e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CFCHMLLK_01020 6.4e-16 ald 1.4.1.1 E alanine dehydrogenase activity
CFCHMLLK_01021 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
CFCHMLLK_01022 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFCHMLLK_01023 2e-94 GBS0088 J protein conserved in bacteria
CFCHMLLK_01024 9.7e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CFCHMLLK_01025 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CFCHMLLK_01026 2.1e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
CFCHMLLK_01027 9.9e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CFCHMLLK_01028 5.6e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFCHMLLK_01029 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
CFCHMLLK_01030 2.5e-21
CFCHMLLK_01031 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFCHMLLK_01033 3.5e-07 U protein secretion
CFCHMLLK_01034 1.1e-51 U protein secretion
CFCHMLLK_01036 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
CFCHMLLK_01037 2.6e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CFCHMLLK_01038 4.9e-21 XK27_13030
CFCHMLLK_01039 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFCHMLLK_01040 3.8e-168 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CFCHMLLK_01041 2.9e-162 S Protein of unknown function (DUF3114)
CFCHMLLK_01042 1.2e-22 S Protein of unknown function (DUF3114)
CFCHMLLK_01043 5.8e-118 yqfA K protein, Hemolysin III
CFCHMLLK_01044 2.2e-232 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CFCHMLLK_01045 1.4e-217 mvaS 2.3.3.10 I synthase
CFCHMLLK_01046 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFCHMLLK_01047 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CFCHMLLK_01048 9.7e-22
CFCHMLLK_01049 5.7e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFCHMLLK_01050 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
CFCHMLLK_01051 1.1e-248 mmuP E amino acid
CFCHMLLK_01052 4.5e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
CFCHMLLK_01053 1.4e-29 S Domain of unknown function (DUF1912)
CFCHMLLK_01054 3.7e-15 L Helix-hairpin-helix DNA-binding motif class 1
CFCHMLLK_01055 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CFCHMLLK_01056 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFCHMLLK_01057 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFCHMLLK_01058 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
CFCHMLLK_01059 4.8e-16 S Protein of unknown function (DUF2969)
CFCHMLLK_01062 1.9e-204 rpsA 1.17.7.4 J ribosomal protein S1
CFCHMLLK_01065 6.9e-102 S Domain of Unknown Function with PDB structure (DUF3862)
CFCHMLLK_01066 3.7e-70 M Pfam SNARE associated Golgi protein
CFCHMLLK_01067 1.1e-231 murN 2.3.2.10, 2.3.2.16 V FemAB family
CFCHMLLK_01068 7.8e-08 S oxidoreductase
CFCHMLLK_01069 3.2e-43 yvaA 1.1.1.371 S inositol 2-dehydrogenase activity
CFCHMLLK_01070 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
CFCHMLLK_01071 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CFCHMLLK_01072 0.0 clpE O Belongs to the ClpA ClpB family
CFCHMLLK_01073 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFCHMLLK_01074 1.3e-34 ykuJ S protein conserved in bacteria
CFCHMLLK_01075 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
CFCHMLLK_01076 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
CFCHMLLK_01077 1.1e-78 feoA P FeoA domain protein
CFCHMLLK_01078 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CFCHMLLK_01079 1.5e-07
CFCHMLLK_01080 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CFCHMLLK_01081 2.2e-45 K sequence-specific DNA binding
CFCHMLLK_01082 2.5e-33 yugF I carboxylic ester hydrolase activity
CFCHMLLK_01083 1.5e-23 I Alpha/beta hydrolase family
CFCHMLLK_01084 2.7e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFCHMLLK_01085 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFCHMLLK_01086 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
CFCHMLLK_01087 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFCHMLLK_01088 1.4e-62 licT K transcriptional antiterminator
CFCHMLLK_01089 1.4e-50 licT K transcriptional antiterminator
CFCHMLLK_01090 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFCHMLLK_01091 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CFCHMLLK_01092 3.7e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFCHMLLK_01093 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CFCHMLLK_01094 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CFCHMLLK_01095 2.9e-221 mdtG EGP Major facilitator Superfamily
CFCHMLLK_01096 2e-33 secG U Preprotein translocase subunit SecG
CFCHMLLK_01097 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CFCHMLLK_01098 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CFCHMLLK_01099 9e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFCHMLLK_01100 8.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
CFCHMLLK_01101 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
CFCHMLLK_01102 9.9e-183 ccpA K Catabolite control protein A
CFCHMLLK_01103 4e-27 yyaQ S YjbR
CFCHMLLK_01104 1.4e-141 yyaQ S YjbR
CFCHMLLK_01105 1.1e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CFCHMLLK_01106 4.5e-74 yueI S Protein of unknown function (DUF1694)
CFCHMLLK_01107 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CFCHMLLK_01109 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CFCHMLLK_01110 2.6e-219 ywbD 2.1.1.191 J Methyltransferase
CFCHMLLK_01111 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CFCHMLLK_01112 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFCHMLLK_01113 6.5e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFCHMLLK_01114 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFCHMLLK_01115 3.5e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CFCHMLLK_01116 3.2e-53 yheA S Belongs to the UPF0342 family
CFCHMLLK_01117 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CFCHMLLK_01118 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CFCHMLLK_01119 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFCHMLLK_01120 1.9e-152 pheA 4.2.1.51 E Prephenate dehydratase
CFCHMLLK_01121 1.4e-246 msrR K Transcriptional regulator
CFCHMLLK_01122 3.5e-123 ydiA P C4-dicarboxylate transporter malic acid transport
CFCHMLLK_01123 1.7e-201 I acyl-CoA dehydrogenase
CFCHMLLK_01124 2.2e-96 mip S hydroperoxide reductase activity
CFCHMLLK_01125 8e-252 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFCHMLLK_01126 2.9e-21
CFCHMLLK_01127 3.5e-138 repA S Replication initiator protein A (RepA) N-terminus
CFCHMLLK_01128 3e-259 hpaIIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
CFCHMLLK_01129 6.3e-78 XK27_00590
CFCHMLLK_01130 4.2e-65 XK27_00585 P arsenate reductase (glutaredoxin) activity
CFCHMLLK_01131 5.9e-38 XK27_00580
CFCHMLLK_01132 1.2e-90 ypbD S CAAX protease self-immunity
CFCHMLLK_01133 2.9e-79 XK27_00570
CFCHMLLK_01134 0.0 traG U Type IV secretory system Conjugative DNA transfer
CFCHMLLK_01135 9.2e-34 XK27_00560
CFCHMLLK_01136 2e-139
CFCHMLLK_01137 7.5e-61 XK27_00550 S PrgI family protein
CFCHMLLK_01138 0.0 U 'COG3451 Type IV secretory pathway, VirB4 components'
CFCHMLLK_01139 0.0 XK27_00530 S CHAP domain
CFCHMLLK_01140 1.5e-154 V Abi-like protein
CFCHMLLK_01141 0.0 XK27_00515 D Glucan-binding protein C
CFCHMLLK_01142 2.4e-13 XK27_00510
CFCHMLLK_01143 1.7e-91 XK27_00505
CFCHMLLK_01144 0.0 XK27_00500 L SNF2 family N-terminal domain
CFCHMLLK_01145 1.9e-41
CFCHMLLK_01146 1.5e-38
CFCHMLLK_01147 5.4e-73 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CFCHMLLK_01148 3.1e-92 pat 2.3.1.183 M acetyltransferase
CFCHMLLK_01149 8.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFCHMLLK_01150 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFCHMLLK_01151 3.2e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CFCHMLLK_01152 0.0 smc D Required for chromosome condensation and partitioning
CFCHMLLK_01153 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFCHMLLK_01154 2.7e-91 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFCHMLLK_01155 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFCHMLLK_01158 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
CFCHMLLK_01159 8.5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFCHMLLK_01161 2e-86 S ECF-type riboflavin transporter, S component
CFCHMLLK_01162 5.5e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
CFCHMLLK_01163 5.9e-82 XK27_01265 S ECF-type riboflavin transporter, S component
CFCHMLLK_01164 4e-292 yfmM S abc transporter atp-binding protein
CFCHMLLK_01165 1.7e-257 noxE P NADH oxidase
CFCHMLLK_01166 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CFCHMLLK_01167 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFCHMLLK_01168 4.8e-129 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
CFCHMLLK_01169 2.7e-54 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
CFCHMLLK_01170 1.4e-162 ypuA S secreted protein
CFCHMLLK_01171 2.1e-61 L Transposase (IS116 IS110 IS902 family)
CFCHMLLK_01172 1.4e-71 L Transposase (IS116 IS110 IS902 family)
CFCHMLLK_01174 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFCHMLLK_01175 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFCHMLLK_01176 2.2e-34 nrdH O Glutaredoxin
CFCHMLLK_01177 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFCHMLLK_01178 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
CFCHMLLK_01179 8.8e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
CFCHMLLK_01180 7.9e-39 ptsH G phosphocarrier protein Hpr
CFCHMLLK_01181 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFCHMLLK_01182 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
CFCHMLLK_01183 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CFCHMLLK_01184 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
CFCHMLLK_01185 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
CFCHMLLK_01186 0.0 uup S abc transporter atp-binding protein
CFCHMLLK_01188 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
CFCHMLLK_01189 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFCHMLLK_01190 8.7e-150 cobQ S glutamine amidotransferase
CFCHMLLK_01191 2.2e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
CFCHMLLK_01192 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CFCHMLLK_01193 2.3e-168 ybbR S Protein conserved in bacteria
CFCHMLLK_01194 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFCHMLLK_01195 1.3e-70 gtrA S GtrA-like protein
CFCHMLLK_01196 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
CFCHMLLK_01197 1.6e-148 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFCHMLLK_01198 2.3e-103 zupT P Mediates zinc uptake. May also transport other divalent cations
CFCHMLLK_01199 1.3e-207 yurR 1.4.5.1 E oxidoreductase
CFCHMLLK_01200 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFCHMLLK_01201 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CFCHMLLK_01202 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CFCHMLLK_01206 1.3e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
CFCHMLLK_01207 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
CFCHMLLK_01208 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CFCHMLLK_01209 4e-121 ylfI S tigr01906
CFCHMLLK_01210 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
CFCHMLLK_01211 3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CFCHMLLK_01212 2e-89 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CFCHMLLK_01213 9e-238 rodA D Belongs to the SEDS family
CFCHMLLK_01214 1.2e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFCHMLLK_01215 1.2e-117 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CFCHMLLK_01216 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CFCHMLLK_01217 1.1e-138 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CFCHMLLK_01218 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
CFCHMLLK_01219 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFCHMLLK_01220 1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFCHMLLK_01221 2.9e-125 dnaD
CFCHMLLK_01222 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFCHMLLK_01225 3.4e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFCHMLLK_01226 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
CFCHMLLK_01227 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CFCHMLLK_01228 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CFCHMLLK_01229 1.1e-72 argR K arginine binding
CFCHMLLK_01230 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
CFCHMLLK_01231 1.7e-148 DegV S DegV family
CFCHMLLK_01232 1.3e-143 ypmR E lipolytic protein G-D-S-L family
CFCHMLLK_01233 5.8e-95 ypmS S Protein conserved in bacteria
CFCHMLLK_01234 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CFCHMLLK_01236 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
CFCHMLLK_01237 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFCHMLLK_01238 7.6e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFCHMLLK_01239 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CFCHMLLK_01240 2.5e-43 ysdA L Membrane
CFCHMLLK_01241 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFCHMLLK_01242 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFCHMLLK_01243 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
CFCHMLLK_01244 0.0 dnaE 2.7.7.7 L DNA polymerase
CFCHMLLK_01245 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CFCHMLLK_01246 3.5e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CFCHMLLK_01249 5.4e-27 Q the current gene model (or a revised gene model) may contain a frame shift
CFCHMLLK_01250 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
CFCHMLLK_01252 4.2e-17 S Domain of unknown function (DUF4649)
CFCHMLLK_01253 9.5e-178 XK27_08835 S ABC transporter substrate binding protein
CFCHMLLK_01254 5.2e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
CFCHMLLK_01255 1.2e-135 XK27_08845 S abc transporter atp-binding protein
CFCHMLLK_01256 2.1e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFCHMLLK_01257 1.6e-151 estA CE1 S Putative esterase
CFCHMLLK_01258 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
CFCHMLLK_01259 2.5e-14 XK27_08880
CFCHMLLK_01260 1e-75 fld C Flavodoxin
CFCHMLLK_01261 2.9e-282 clcA P Chloride transporter, ClC family
CFCHMLLK_01262 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
CFCHMLLK_01263 2.3e-218 XK27_05110 P chloride
CFCHMLLK_01264 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CFCHMLLK_01267 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
CFCHMLLK_01268 4.9e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFCHMLLK_01269 6.1e-88 ytsP 1.8.4.14 T GAF domain-containing protein
CFCHMLLK_01270 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFCHMLLK_01272 7.8e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CFCHMLLK_01273 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFCHMLLK_01274 8.3e-28 G Domain of unknown function (DUF4832)
CFCHMLLK_01275 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CFCHMLLK_01277 3.8e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFCHMLLK_01278 6.1e-25 epuA S DNA-directed RNA polymerase subunit beta
CFCHMLLK_01279 2.4e-124 endA F DNA RNA non-specific endonuclease
CFCHMLLK_01280 1.7e-111 tcyB_2 P ABC transporter (permease)
CFCHMLLK_01281 2.7e-118 gltJ P ABC transporter (Permease
CFCHMLLK_01282 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CFCHMLLK_01283 3.6e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
CFCHMLLK_01284 7.6e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFCHMLLK_01285 3.9e-235 vicK 2.7.13.3 T Histidine kinase
CFCHMLLK_01286 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
CFCHMLLK_01287 2e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
CFCHMLLK_01288 9.2e-147 yidA S hydrolases of the HAD superfamily
CFCHMLLK_01289 7.7e-49 XK27_00115 2.3.1.128 K acetyltransferase
CFCHMLLK_01290 2.6e-67 ywiB S Domain of unknown function (DUF1934)
CFCHMLLK_01291 0.0 pacL 3.6.3.8 P cation transport ATPase
CFCHMLLK_01292 6.7e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CFCHMLLK_01293 6.6e-181 yjjH S Calcineurin-like phosphoesterase
CFCHMLLK_01294 7.9e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFCHMLLK_01295 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFCHMLLK_01296 2.5e-124 ftsE D cell division ATP-binding protein FtsE
CFCHMLLK_01297 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CFCHMLLK_01298 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
CFCHMLLK_01299 1.7e-178 yubA S permease
CFCHMLLK_01300 4.9e-224 G COG0457 FOG TPR repeat
CFCHMLLK_01301 1.2e-97 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CFCHMLLK_01302 8.8e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CFCHMLLK_01303 2.9e-90 ebsA S Family of unknown function (DUF5322)
CFCHMLLK_01304 5e-23 M LysM domain
CFCHMLLK_01305 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CFCHMLLK_01306 9.8e-89 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFCHMLLK_01307 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CFCHMLLK_01308 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFCHMLLK_01309 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CFCHMLLK_01310 7.1e-278 amiC P ABC transporter (Permease
CFCHMLLK_01311 4.9e-168 amiD P ABC transporter (Permease
CFCHMLLK_01312 2.2e-204 oppD P Belongs to the ABC transporter superfamily
CFCHMLLK_01313 4.3e-172 oppF P Belongs to the ABC transporter superfamily
CFCHMLLK_01314 6.2e-132 V ATPase activity
CFCHMLLK_01315 9.8e-121 skfE V abc transporter atp-binding protein
CFCHMLLK_01316 8.6e-63 yvoA_1 K Transcriptional
CFCHMLLK_01317 2e-146 supH S overlaps another CDS with the same product name
CFCHMLLK_01318 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
CFCHMLLK_01319 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CFCHMLLK_01320 2.6e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CFCHMLLK_01321 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
CFCHMLLK_01322 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFCHMLLK_01323 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFCHMLLK_01324 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFCHMLLK_01325 2e-132 stp 3.1.3.16 T phosphatase
CFCHMLLK_01326 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CFCHMLLK_01327 3.7e-120 yvqF KT membrane
CFCHMLLK_01328 5.8e-175 vraS 2.7.13.3 T Histidine kinase
CFCHMLLK_01329 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFCHMLLK_01332 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CFCHMLLK_01333 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CFCHMLLK_01334 3.5e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CFCHMLLK_01335 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CFCHMLLK_01336 4.6e-73 L Transposase
CFCHMLLK_01337 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
CFCHMLLK_01338 8.9e-30 V (ABC) transporter
CFCHMLLK_01339 2.5e-101 V abc transporter atp-binding protein
CFCHMLLK_01340 5.1e-61 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
CFCHMLLK_01341 1e-134 M translation initiation factor activity
CFCHMLLK_01342 5e-32 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
CFCHMLLK_01343 1.2e-25 L transposition
CFCHMLLK_01344 7.1e-09 L Integrase core domain protein
CFCHMLLK_01345 2.3e-184 galR K Transcriptional regulator
CFCHMLLK_01346 1.3e-218 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFCHMLLK_01347 4.2e-294 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CFCHMLLK_01348 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CFCHMLLK_01349 4.4e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CFCHMLLK_01350 0.0 lacS G transporter
CFCHMLLK_01351 0.0 lacL 3.2.1.23 G -beta-galactosidase
CFCHMLLK_01352 3.4e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CFCHMLLK_01353 0.0 sbcC L ATPase involved in DNA repair
CFCHMLLK_01354 6.4e-21
CFCHMLLK_01355 0.0 M family 8
CFCHMLLK_01356 7.9e-09
CFCHMLLK_01357 5.8e-109 MA20_06410 E LysE type translocator
CFCHMLLK_01358 2e-11 IQ PFAM AMP-dependent synthetase and ligase
CFCHMLLK_01359 9.9e-76
CFCHMLLK_01360 1.7e-268 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFCHMLLK_01361 7.6e-61
CFCHMLLK_01363 1.1e-69 S Signal peptide protein, YSIRK family
CFCHMLLK_01364 4.8e-55 K response regulator
CFCHMLLK_01365 1.1e-37 BP1961 P nitric oxide dioxygenase activity
CFCHMLLK_01367 1.1e-283 XK27_07020 S Belongs to the UPF0371 family
CFCHMLLK_01368 8.3e-93 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CFCHMLLK_01369 1.5e-160 yvgN C reductase
CFCHMLLK_01371 3e-56 yoaK S Protein of unknown function (DUF1275)
CFCHMLLK_01372 2.1e-14 yoaK S Protein of unknown function (DUF1275)
CFCHMLLK_01373 1.3e-111 drgA C Nitroreductase
CFCHMLLK_01374 3.7e-230 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFCHMLLK_01375 1.9e-158 E Alpha/beta hydrolase of unknown function (DUF915)
CFCHMLLK_01376 5.6e-77 ywnA K Transcriptional regulator
CFCHMLLK_01377 1.1e-89 1.13.11.2 S glyoxalase
CFCHMLLK_01378 3.5e-16 1.13.11.2 S glyoxalase
CFCHMLLK_01379 2.8e-108 XK27_02070 S nitroreductase
CFCHMLLK_01380 5.3e-227 yfnA E amino acid
CFCHMLLK_01381 9.6e-26 csbD K CsbD-like
CFCHMLLK_01382 5.7e-58 manA 5.3.1.8 G mannose-6-phosphate isomerase
CFCHMLLK_01383 7.2e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
CFCHMLLK_01384 8.6e-235 brnQ E Component of the transport system for branched-chain amino acids
CFCHMLLK_01385 3.9e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CFCHMLLK_01386 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
CFCHMLLK_01387 5.7e-102 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
CFCHMLLK_01388 5.4e-148 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
CFCHMLLK_01389 3e-115 yxeQ S MmgE/PrpD family
CFCHMLLK_01390 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
CFCHMLLK_01391 4.1e-63 yxeN U ABC transporter, permease protein
CFCHMLLK_01392 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
CFCHMLLK_01393 1.1e-197 pcaB 4.3.2.2 F Adenylosuccinate lyase
CFCHMLLK_01394 2.6e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
CFCHMLLK_01395 1.8e-186 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFCHMLLK_01396 7.6e-247 norM V Multidrug efflux pump
CFCHMLLK_01397 5.9e-115 pbuX F xanthine permease
CFCHMLLK_01398 1.1e-75 pbuX F xanthine permease
CFCHMLLK_01400 8.6e-76 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CFCHMLLK_01401 7.8e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFCHMLLK_01402 3.1e-165 T Histidine kinase
CFCHMLLK_01403 1.9e-133 macB2 V ABC transporter, ATP-binding protein
CFCHMLLK_01404 0.0 V ABC transporter (permease)
CFCHMLLK_01405 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
CFCHMLLK_01406 4.4e-30 liaI KT membrane
CFCHMLLK_01407 2.4e-15 liaI KT membrane
CFCHMLLK_01408 1.2e-26 XK27_09825 V 'abc transporter, ATP-binding protein
CFCHMLLK_01409 3.7e-122 S An automated process has identified a potential problem with this gene model
CFCHMLLK_01411 4.4e-49 3.6.1.55 F NUDIX domain
CFCHMLLK_01412 1e-151 mutR K Transcriptional activator, Rgg GadR MutR family
CFCHMLLK_01413 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
CFCHMLLK_01414 1.4e-210 EGP Major facilitator Superfamily
CFCHMLLK_01415 3.9e-08
CFCHMLLK_01416 4.3e-74 XK27_01300 P Protein conserved in bacteria
CFCHMLLK_01417 2.8e-64 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CFCHMLLK_01418 4.8e-46 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CFCHMLLK_01419 8.9e-67 MA20_25245 K Acetyltransferase (GNAT) family
CFCHMLLK_01420 7.8e-60
CFCHMLLK_01421 6.2e-17
CFCHMLLK_01422 4.1e-34 M translation initiation factor activity
CFCHMLLK_01423 4.7e-22 P ABC transporter transmembrane region
CFCHMLLK_01424 4.4e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
CFCHMLLK_01425 2.6e-161 yocS S Transporter
CFCHMLLK_01428 6.9e-156 XK27_09825 V abc transporter atp-binding protein
CFCHMLLK_01429 4.8e-134 yvfS V ABC-2 type transporter
CFCHMLLK_01430 1.9e-187 desK 2.7.13.3 T Histidine kinase
CFCHMLLK_01431 1.1e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFCHMLLK_01432 7.8e-100 S transport system, permease component
CFCHMLLK_01433 2.2e-94 S ABC-2 family transporter protein
CFCHMLLK_01434 1.6e-149 sdaAA 4.3.1.17 E L-serine dehydratase
CFCHMLLK_01435 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
CFCHMLLK_01436 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CFCHMLLK_01437 5.4e-206 S Protein of unknown function (DUF917)
CFCHMLLK_01438 4.5e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
CFCHMLLK_01439 3e-111 proWZ P ABC transporter (Permease
CFCHMLLK_01440 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
CFCHMLLK_01441 1.5e-138 proV E abc transporter atp-binding protein
CFCHMLLK_01442 3.6e-90 proW P Binding-protein-dependent transport system inner membrane component
CFCHMLLK_01443 8e-62 bioY S biotin transmembrane transporter activity
CFCHMLLK_01444 4.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
CFCHMLLK_01445 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CFCHMLLK_01446 9.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFCHMLLK_01447 1.7e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
CFCHMLLK_01448 3.2e-105 mur1 NU mannosyl-glycoprotein
CFCHMLLK_01449 6.6e-54 glnB K Belongs to the P(II) protein family
CFCHMLLK_01450 5.8e-233 amt P Ammonium Transporter
CFCHMLLK_01451 1.7e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFCHMLLK_01452 9.5e-55 yabA L Involved in initiation control of chromosome replication
CFCHMLLK_01453 2.1e-135 yaaT S stage 0 sporulation protein
CFCHMLLK_01454 6.4e-162 holB 2.7.7.7 L dna polymerase iii
CFCHMLLK_01455 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFCHMLLK_01456 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CFCHMLLK_01457 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFCHMLLK_01458 2.8e-230 ftsW D Belongs to the SEDS family
CFCHMLLK_01459 1.5e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CFCHMLLK_01460 7.9e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFCHMLLK_01461 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFCHMLLK_01462 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFCHMLLK_01463 1.3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFCHMLLK_01464 3.3e-78 atpF C ATP synthase F(0) sector subunit b
CFCHMLLK_01465 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
CFCHMLLK_01466 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFCHMLLK_01467 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CFCHMLLK_01468 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFCHMLLK_01469 1.7e-102 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFCHMLLK_01470 8.9e-14 coiA 3.6.4.12 S Competence protein
CFCHMLLK_01471 2.3e-17 T peptidase
CFCHMLLK_01472 9.4e-153 rarD S Transporter
CFCHMLLK_01473 8.3e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CFCHMLLK_01474 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CFCHMLLK_01475 1.6e-140 yxkH G deacetylase
CFCHMLLK_01476 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CFCHMLLK_01477 1e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CFCHMLLK_01478 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFCHMLLK_01479 1.7e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFCHMLLK_01480 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
CFCHMLLK_01481 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CFCHMLLK_01482 3.2e-105 3.4.17.14, 3.5.1.28 NU amidase activity
CFCHMLLK_01483 2.6e-172 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CFCHMLLK_01484 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFCHMLLK_01485 1.2e-176 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
CFCHMLLK_01486 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
CFCHMLLK_01487 0.0 pepF E oligoendopeptidase F
CFCHMLLK_01488 9.1e-186 coiA 3.6.4.12 S Competence protein
CFCHMLLK_01489 1.2e-166 K transcriptional regulator (lysR family)
CFCHMLLK_01490 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFCHMLLK_01494 8e-191 phoH T phosphate starvation-inducible protein PhoH
CFCHMLLK_01495 3e-60 rlpA M LysM domain protein
CFCHMLLK_01496 6.1e-115 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
CFCHMLLK_01497 7.4e-35 yozE S Belongs to the UPF0346 family
CFCHMLLK_01498 5.3e-161 cvfB S Protein conserved in bacteria
CFCHMLLK_01499 9.9e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CFCHMLLK_01500 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CFCHMLLK_01501 2.6e-121 sptS 2.7.13.3 T Histidine kinase
CFCHMLLK_01502 5.4e-45 K Acetyltransferase (GNAT) family
CFCHMLLK_01503 0.0 lmrA2 V abc transporter atp-binding protein
CFCHMLLK_01504 0.0 lmrA1 V abc transporter atp-binding protein
CFCHMLLK_01505 1.9e-77 K DNA-binding transcription factor activity
CFCHMLLK_01507 7.9e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CFCHMLLK_01508 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
CFCHMLLK_01509 2.4e-86 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
CFCHMLLK_01510 8.5e-69 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
CFCHMLLK_01511 6.5e-77 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
CFCHMLLK_01512 1.6e-24 U response to pH
CFCHMLLK_01513 0.0 yfmR S abc transporter atp-binding protein
CFCHMLLK_01514 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CFCHMLLK_01515 1.1e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CFCHMLLK_01516 5.4e-53 XK27_08360 T EDD domain protein, DegV family
CFCHMLLK_01517 2.9e-31 XK27_08360 S lipid binding
CFCHMLLK_01518 2.6e-64 WQ51_03320 S cog cog4835
CFCHMLLK_01519 1e-122 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFCHMLLK_01520 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CFCHMLLK_01521 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CFCHMLLK_01522 5.4e-28 2.3.1.128 K acetyltransferase
CFCHMLLK_01523 1.1e-38 2.3.1.128 K acetyltransferase
CFCHMLLK_01524 1.8e-256 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CFCHMLLK_01525 5.5e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CFCHMLLK_01526 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFCHMLLK_01527 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
CFCHMLLK_01529 3.1e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CFCHMLLK_01530 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFCHMLLK_01531 1.1e-47 fruA 2.7.1.202 G phosphotransferase system
CFCHMLLK_01532 7.3e-140 fruA 2.7.1.202 G phosphotransferase system
CFCHMLLK_01533 1.4e-114 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
CFCHMLLK_01534 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CFCHMLLK_01535 3.6e-113 fruR K transcriptional
CFCHMLLK_01536 7.6e-83 L Transposase
CFCHMLLK_01537 1.7e-205 rny D Endoribonuclease that initiates mRNA decay
CFCHMLLK_01538 4.7e-115 3.1.21.3 V Type I restriction modification DNA specificity domain
CFCHMLLK_01539 1.1e-297 hsdM 2.1.1.72 V HsdM N-terminal domain
CFCHMLLK_01540 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
CFCHMLLK_01542 3.1e-122 4.1.1.22 H Histidine carboxylase PI chain
CFCHMLLK_01543 1.3e-170 aaxC E Arginine ornithine antiporter
CFCHMLLK_01545 8.3e-22 L RePlication protein
CFCHMLLK_01546 1.3e-25 L Replication protein
CFCHMLLK_01547 2.5e-125 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
CFCHMLLK_01548 2.9e-25
CFCHMLLK_01549 1e-296 aspT S potassium ion transport
CFCHMLLK_01550 2e-302 asdA 4.1.1.12 E Aminotransferase class I and II
CFCHMLLK_01553 4.3e-67 S Virulence-associated protein E
CFCHMLLK_01554 8.7e-51 KL Phage plasmid primase P4 family
CFCHMLLK_01555 1.7e-145 sip L Belongs to the 'phage' integrase family
CFCHMLLK_01556 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CFCHMLLK_01557 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CFCHMLLK_01558 2e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFCHMLLK_01559 1.1e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CFCHMLLK_01560 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CFCHMLLK_01561 1.3e-55 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CFCHMLLK_01562 7.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFCHMLLK_01563 1.3e-126 IQ reductase
CFCHMLLK_01564 5.5e-164 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CFCHMLLK_01565 1.2e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
CFCHMLLK_01566 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFCHMLLK_01567 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFCHMLLK_01568 4e-72 marR K Transcriptional regulator, MarR family
CFCHMLLK_01569 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
CFCHMLLK_01570 1.1e-113 S Haloacid dehalogenase-like hydrolase
CFCHMLLK_01571 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
CFCHMLLK_01572 1.8e-87 S Fusaric acid resistance protein-like
CFCHMLLK_01573 3.2e-62 glnR K Transcriptional regulator
CFCHMLLK_01574 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
CFCHMLLK_01575 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFCHMLLK_01576 2.5e-33 ykzG S Belongs to the UPF0356 family
CFCHMLLK_01577 1.6e-120 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
CFCHMLLK_01578 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CFCHMLLK_01579 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFCHMLLK_01580 4.7e-115 azlC E AzlC protein
CFCHMLLK_01581 8.8e-48 azlD E branched-chain amino acid
CFCHMLLK_01582 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CFCHMLLK_01583 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CFCHMLLK_01584 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFCHMLLK_01585 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CFCHMLLK_01586 1.1e-92 cvpA S toxin biosynthetic process
CFCHMLLK_01587 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CFCHMLLK_01588 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFCHMLLK_01592 4.2e-230 mutY L A G-specific adenine glycosylase
CFCHMLLK_01593 4.7e-41 XK27_05745
CFCHMLLK_01594 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
CFCHMLLK_01595 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CFCHMLLK_01596 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFCHMLLK_01598 3.1e-124 XK27_01040 S Pfam PF06570
CFCHMLLK_01599 5.8e-169 corA P COG0598 Mg2 and Co2 transporters
CFCHMLLK_01600 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFCHMLLK_01603 8.3e-61 V 'abc transporter, ATP-binding protein
CFCHMLLK_01604 1.6e-44 V 'abc transporter, ATP-binding protein
CFCHMLLK_01606 2.5e-192 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
CFCHMLLK_01607 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
CFCHMLLK_01608 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFCHMLLK_01609 3.4e-62 yqhY S protein conserved in bacteria
CFCHMLLK_01610 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFCHMLLK_01611 1.7e-179 scrR K Transcriptional
CFCHMLLK_01612 2.5e-288 scrB 3.2.1.26 GH32 G invertase
CFCHMLLK_01613 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
CFCHMLLK_01614 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
CFCHMLLK_01615 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
CFCHMLLK_01617 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CFCHMLLK_01618 1.9e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFCHMLLK_01619 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFCHMLLK_01620 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CFCHMLLK_01621 6.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFCHMLLK_01622 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFCHMLLK_01623 1.8e-181 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CFCHMLLK_01624 9.5e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
CFCHMLLK_01625 8.5e-18 yebC M Membrane
CFCHMLLK_01626 1.2e-77 yebC M Membrane
CFCHMLLK_01627 9.1e-18 KT response to antibiotic
CFCHMLLK_01628 6.5e-68 KT response to antibiotic
CFCHMLLK_01629 5.4e-10 XK27_02470 K LytTr DNA-binding domain protein
CFCHMLLK_01630 2.6e-66 liaI S membrane
CFCHMLLK_01631 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CFCHMLLK_01632 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CFCHMLLK_01633 1.6e-11 S Protein of unknown function (DUF554)
CFCHMLLK_01634 1.5e-104 S Protein of unknown function (DUF554)
CFCHMLLK_01635 9.4e-95 ecsA_2 V abc transporter atp-binding protein
CFCHMLLK_01636 9.8e-286 XK27_00765
CFCHMLLK_01637 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFCHMLLK_01638 5.8e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFCHMLLK_01639 1.7e-155
CFCHMLLK_01640 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CFCHMLLK_01641 4.3e-47 ftsL D cell division protein FtsL
CFCHMLLK_01642 0.0 ftsI 3.4.16.4 M penicillin-binding protein
CFCHMLLK_01643 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFCHMLLK_01644 3.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CFCHMLLK_01646 1.1e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CFCHMLLK_01647 2.3e-72 yutD J protein conserved in bacteria
CFCHMLLK_01648 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CFCHMLLK_01649 2.5e-92 XK27_09885 V Glycopeptide antibiotics resistance protein
CFCHMLLK_01651 0.0 mdlA V abc transporter atp-binding protein
CFCHMLLK_01652 0.0 mdlB V abc transporter atp-binding protein
CFCHMLLK_01653 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CFCHMLLK_01654 4e-235 mesE M Transport protein ComB
CFCHMLLK_01656 6.5e-238 blpH 2.7.13.3 T protein histidine kinase activity
CFCHMLLK_01657 5.8e-132 agrA KT phosphorelay signal transduction system
CFCHMLLK_01658 5.1e-17 S Bacteriocin class II with double-glycine leader peptide
CFCHMLLK_01663 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CFCHMLLK_01664 4.2e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
CFCHMLLK_01665 5.2e-84
CFCHMLLK_01666 1.6e-77 sigH K DNA-templated transcription, initiation
CFCHMLLK_01667 1e-148 ykuT M mechanosensitive ion channel
CFCHMLLK_01668 4.9e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CFCHMLLK_01669 6.3e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CFCHMLLK_01670 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CFCHMLLK_01671 2.4e-83 XK27_03960 S Protein of unknown function (DUF3013)
CFCHMLLK_01672 1e-56 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
CFCHMLLK_01673 7.7e-177 prmA J Ribosomal protein L11 methyltransferase
CFCHMLLK_01674 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CFCHMLLK_01675 5.5e-30 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CFCHMLLK_01676 2.2e-105 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CFCHMLLK_01677 7.2e-130 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CFCHMLLK_01678 1.2e-45 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CFCHMLLK_01679 1.7e-81 nrdI F Belongs to the NrdI family
CFCHMLLK_01680 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFCHMLLK_01681 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CFCHMLLK_01682 6.8e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CFCHMLLK_01683 4e-28 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CFCHMLLK_01684 6e-64 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CFCHMLLK_01685 1.5e-40 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CFCHMLLK_01686 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFCHMLLK_01687 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CFCHMLLK_01688 1.2e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
CFCHMLLK_01689 9.3e-201 yhjX P Major Facilitator
CFCHMLLK_01690 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFCHMLLK_01691 1.9e-93 V VanZ like family
CFCHMLLK_01694 1e-123 glnQ E abc transporter atp-binding protein
CFCHMLLK_01695 2e-275 glnP P ABC transporter
CFCHMLLK_01696 3.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CFCHMLLK_01697 1.4e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CFCHMLLK_01698 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
CFCHMLLK_01699 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CFCHMLLK_01700 1.4e-234 sufD O assembly protein SufD
CFCHMLLK_01701 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFCHMLLK_01702 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
CFCHMLLK_01703 2.2e-273 sufB O assembly protein SufB
CFCHMLLK_01704 2.3e-36 oppA E ABC transporter substrate-binding protein
CFCHMLLK_01705 3.6e-137 oppA E ABC transporter substrate-binding protein
CFCHMLLK_01706 8.5e-28 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFCHMLLK_01707 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFCHMLLK_01708 6.2e-09 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFCHMLLK_01709 3.1e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
CFCHMLLK_01710 8.1e-28 oppD P Belongs to the ABC transporter superfamily
CFCHMLLK_01711 6.1e-31 oppD P Belongs to the ABC transporter superfamily
CFCHMLLK_01712 3.3e-68 oppD P Belongs to the ABC transporter superfamily
CFCHMLLK_01713 1.4e-43 oppD P Belongs to the ABC transporter superfamily
CFCHMLLK_01714 8.7e-165 oppF P Belongs to the ABC transporter superfamily
CFCHMLLK_01716 1.1e-10
CFCHMLLK_01717 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFCHMLLK_01718 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFCHMLLK_01719 6e-128 K sequence-specific DNA binding
CFCHMLLK_01720 0.0 KLT serine threonine protein kinase
CFCHMLLK_01721 1.9e-223 EGP Major facilitator Superfamily
CFCHMLLK_01722 3.1e-72 adcR K transcriptional
CFCHMLLK_01723 2.2e-136 adcC P ABC transporter, ATP-binding protein
CFCHMLLK_01724 9.3e-131 adcB P ABC transporter (Permease
CFCHMLLK_01725 2.1e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
CFCHMLLK_01726 1.1e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
CFCHMLLK_01727 9.2e-25 ptsG 2.7.1.199, 2.7.1.208 G pts system
CFCHMLLK_01728 8.4e-258 ptsG 2.7.1.199, 2.7.1.208 G pts system
CFCHMLLK_01729 4.4e-146 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
CFCHMLLK_01730 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
CFCHMLLK_01731 1.9e-127 yeeN K transcriptional regulatory protein
CFCHMLLK_01732 9.8e-50 yajC U protein transport
CFCHMLLK_01733 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFCHMLLK_01734 1.7e-145 cdsA 2.7.7.41 S Belongs to the CDS family
CFCHMLLK_01735 5.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CFCHMLLK_01736 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CFCHMLLK_01737 0.0 WQ51_06230 S ABC transporter substrate binding protein
CFCHMLLK_01738 5.2e-142 cmpC S abc transporter atp-binding protein
CFCHMLLK_01739 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFCHMLLK_01740 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CFCHMLLK_01741 5.7e-77 L transposase activity
CFCHMLLK_01742 5.6e-50 L transposition
CFCHMLLK_01743 2.4e-33 L Integrase core domain protein
CFCHMLLK_01744 2.6e-160 S CHAP domain
CFCHMLLK_01745 2e-241 purD 6.3.4.13 F Belongs to the GARS family
CFCHMLLK_01746 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFCHMLLK_01747 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFCHMLLK_01748 1.8e-62 1.1.1.169 H Ketopantoate reductase
CFCHMLLK_01749 9.8e-62 1.1.1.169 H Ketopantoate reductase
CFCHMLLK_01750 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFCHMLLK_01751 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CFCHMLLK_01752 8.2e-70 argR K Regulates arginine biosynthesis genes
CFCHMLLK_01753 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CFCHMLLK_01754 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFCHMLLK_01755 1.7e-35 S Protein of unknown function (DUF3021)
CFCHMLLK_01756 1.5e-62 KT phosphorelay signal transduction system
CFCHMLLK_01758 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFCHMLLK_01760 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CFCHMLLK_01761 1e-25 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
CFCHMLLK_01762 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
CFCHMLLK_01763 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFCHMLLK_01764 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
CFCHMLLK_01765 1.8e-94 V VanZ like family
CFCHMLLK_01766 1.1e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CFCHMLLK_01767 2.1e-67 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
CFCHMLLK_01768 5.8e-42 G alpha-ribazole phosphatase activity
CFCHMLLK_01769 1.3e-199 S hmm pf01594
CFCHMLLK_01770 4.1e-95 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFCHMLLK_01771 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
CFCHMLLK_01772 1.9e-33 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFCHMLLK_01773 1.3e-39 S granule-associated protein
CFCHMLLK_01774 6.1e-288 S unusual protein kinase
CFCHMLLK_01775 1.4e-75 estA E GDSL-like protein
CFCHMLLK_01776 2.5e-158 rssA S Phospholipase, patatin family
CFCHMLLK_01777 9.5e-217 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFCHMLLK_01778 2.2e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFCHMLLK_01779 4.5e-233 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CFCHMLLK_01780 5.7e-33 S the current gene model (or a revised gene model) may contain a frame shift
CFCHMLLK_01781 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CFCHMLLK_01782 1.1e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CFCHMLLK_01783 1.2e-199 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFCHMLLK_01784 0.0 lpdA 1.8.1.4 C Dehydrogenase
CFCHMLLK_01785 3.4e-122 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CFCHMLLK_01786 1.5e-164 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFCHMLLK_01787 1.5e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFCHMLLK_01788 2e-135 yclP 3.6.3.34 P abc transporter atp-binding protein
CFCHMLLK_01789 5.8e-178 fatB P ABC-type enterochelin transport system, periplasmic component
CFCHMLLK_01790 7.9e-152 ycdO P periplasmic lipoprotein involved in iron transport
CFCHMLLK_01791 1.5e-233 ycdB P peroxidase
CFCHMLLK_01792 1.6e-302 ywbL P COG0672 High-affinity Fe2 Pb2 permease
CFCHMLLK_01793 1.3e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFCHMLLK_01794 4.6e-25 tatA U protein secretion
CFCHMLLK_01795 1.1e-111 malF P ABC transporter (Permease
CFCHMLLK_01796 5.5e-49 malX G maltose binding
CFCHMLLK_01797 3.8e-16 malX G maltose binding
CFCHMLLK_01798 2e-19 malX G ABC transporter
CFCHMLLK_01799 5.6e-178 malR K Transcriptional regulator
CFCHMLLK_01800 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
CFCHMLLK_01801 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CFCHMLLK_01802 1.4e-08
CFCHMLLK_01803 4.3e-17
CFCHMLLK_01804 1.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
CFCHMLLK_01806 2.7e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
CFCHMLLK_01807 0.0 pepN 3.4.11.2 E aminopeptidase
CFCHMLLK_01808 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
CFCHMLLK_01809 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFCHMLLK_01810 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFCHMLLK_01811 1.2e-155 pstA P phosphate transport system permease
CFCHMLLK_01812 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
CFCHMLLK_01813 2.8e-157 pstS P phosphate
CFCHMLLK_01814 1.5e-255 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CFCHMLLK_01815 2.5e-141 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CFCHMLLK_01816 2.3e-44 yktA S Belongs to the UPF0223 family
CFCHMLLK_01817 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CFCHMLLK_01818 4.9e-173 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CFCHMLLK_01819 8.4e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFCHMLLK_01820 8.1e-214 XK27_04775 S hemerythrin HHE cation binding domain
CFCHMLLK_01821 3.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
CFCHMLLK_01822 1.5e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CFCHMLLK_01823 9.3e-62 S haloacid dehalogenase-like hydrolase
CFCHMLLK_01824 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
CFCHMLLK_01825 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CFCHMLLK_01826 1.8e-240 agcS E (Alanine) symporter
CFCHMLLK_01827 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFCHMLLK_01828 1e-22 bglC K Transcriptional regulator
CFCHMLLK_01829 4e-38 yfiF3 K sequence-specific DNA binding
CFCHMLLK_01830 1.1e-25 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
CFCHMLLK_01831 1.9e-23 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
CFCHMLLK_01832 6.7e-227 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
CFCHMLLK_01834 9.2e-22 yecS P amino acid transport
CFCHMLLK_01835 7.9e-12 artJ_1 ET Belongs to the bacterial solute-binding protein 3 family
CFCHMLLK_01836 1.1e-20 yckB ET Belongs to the bacterial solute-binding protein 3 family
CFCHMLLK_01837 7.3e-72 yckB ET Belongs to the bacterial solute-binding protein 3 family
CFCHMLLK_01838 2.9e-63 nylA 3.5.1.4 J Belongs to the amidase family
CFCHMLLK_01839 1.2e-39
CFCHMLLK_01840 3e-265 dtpT E transporter
CFCHMLLK_01841 4.5e-37 nylA 3.5.1.4 J Belongs to the amidase family
CFCHMLLK_01842 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFCHMLLK_01843 7e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CFCHMLLK_01844 7.5e-61 csm6 S Psort location Cytoplasmic, score
CFCHMLLK_01845 4.1e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
CFCHMLLK_01846 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
CFCHMLLK_01847 9e-116 csm3 L RAMP superfamily
CFCHMLLK_01848 2.5e-62 csm2 L Csm2 Type III-A
CFCHMLLK_01849 0.0 csm1 S CRISPR-associated protein Csm1 family
CFCHMLLK_01850 6.8e-133 cas6 S Pfam:DUF2276
CFCHMLLK_01851 3.7e-54 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CFCHMLLK_01852 1.2e-183 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CFCHMLLK_01853 9.3e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CFCHMLLK_01854 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CFCHMLLK_01855 1.1e-95 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
CFCHMLLK_01856 2.9e-116 S TraX protein
CFCHMLLK_01858 2.4e-68 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)