ORF_ID e_value Gene_name EC_number CAZy COGs Description
PPPBDBBI_00003 1.1e-151 V MatE
PPPBDBBI_00005 1.5e-109 C Fe-S oxidoreductases
PPPBDBBI_00006 1.2e-176 EGP Major Facilitator Superfamily
PPPBDBBI_00007 1.7e-229 I radical SAM domain protein
PPPBDBBI_00008 4.3e-19 I radical SAM domain protein
PPPBDBBI_00010 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPBDBBI_00011 1.5e-149 L Integrase core domain protein
PPPBDBBI_00012 6.1e-18 L transposase activity
PPPBDBBI_00013 8.1e-54 L transposase activity
PPPBDBBI_00015 3.9e-92
PPPBDBBI_00016 0.0 sbcC L ATPase involved in DNA repair
PPPBDBBI_00017 6.9e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PPPBDBBI_00018 0.0 lacL 3.2.1.23 G -beta-galactosidase
PPPBDBBI_00019 0.0 lacS G transporter
PPPBDBBI_00020 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PPPBDBBI_00021 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPPBDBBI_00022 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PPPBDBBI_00023 6.9e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PPPBDBBI_00024 2.3e-184 galR K Transcriptional regulator
PPPBDBBI_00025 2.7e-08 L Integrase core domain protein
PPPBDBBI_00026 1.2e-25 L transposition
PPPBDBBI_00027 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
PPPBDBBI_00028 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
PPPBDBBI_00029 2.5e-101 V abc transporter atp-binding protein
PPPBDBBI_00030 4.3e-40 V abc transporter atp-binding protein
PPPBDBBI_00031 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
PPPBDBBI_00032 6.4e-62 L Transposase
PPPBDBBI_00033 7e-150 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPBDBBI_00034 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPBDBBI_00035 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPBDBBI_00036 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PPPBDBBI_00037 5.9e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PPPBDBBI_00038 7.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PPPBDBBI_00039 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PPPBDBBI_00042 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPPBDBBI_00043 5.8e-175 vraS 2.7.13.3 T Histidine kinase
PPPBDBBI_00044 3.7e-120 yvqF KT membrane
PPPBDBBI_00045 7e-307 prkC 2.7.11.1 KLT serine threonine protein kinase
PPPBDBBI_00046 2e-132 stp 3.1.3.16 T phosphatase
PPPBDBBI_00047 4.4e-247 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PPPBDBBI_00048 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PPPBDBBI_00049 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PPPBDBBI_00050 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
PPPBDBBI_00051 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PPPBDBBI_00052 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PPPBDBBI_00053 6.9e-150 XK27_02985 S overlaps another CDS with the same product name
PPPBDBBI_00054 2.1e-148 supH S overlaps another CDS with the same product name
PPPBDBBI_00055 8.6e-63 yvoA_1 K Transcriptional
PPPBDBBI_00056 2.8e-120 skfE V abc transporter atp-binding protein
PPPBDBBI_00057 3.3e-133 V ATPase activity
PPPBDBBI_00058 4.3e-172 oppF P Belongs to the ABC transporter superfamily
PPPBDBBI_00059 2.2e-204 oppD P Belongs to the ABC transporter superfamily
PPPBDBBI_00060 4.9e-168 amiD P ABC transporter (Permease
PPPBDBBI_00061 4.2e-278 amiC P ABC transporter (Permease
PPPBDBBI_00062 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PPPBDBBI_00063 0.0 M family 8
PPPBDBBI_00064 2.7e-09
PPPBDBBI_00065 5.6e-08
PPPBDBBI_00066 5.8e-109 MA20_06410 E LysE type translocator
PPPBDBBI_00067 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
PPPBDBBI_00068 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
PPPBDBBI_00069 1.9e-35
PPPBDBBI_00070 5.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPPBDBBI_00071 4.5e-61
PPPBDBBI_00072 9.3e-72 S Signal peptide protein, YSIRK family
PPPBDBBI_00073 4.8e-55 K response regulator
PPPBDBBI_00075 1.5e-283 XK27_07020 S Belongs to the UPF0371 family
PPPBDBBI_00076 1e-181 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPPBDBBI_00077 1.2e-160 yvgN C reductase
PPPBDBBI_00078 3e-102 yoaK S Protein of unknown function (DUF1275)
PPPBDBBI_00079 1.4e-110 drgA C Nitroreductase
PPPBDBBI_00080 1.9e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PPPBDBBI_00081 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
PPPBDBBI_00082 5.6e-77 ywnA K Transcriptional regulator
PPPBDBBI_00083 9.5e-150 1.13.11.2 S glyoxalase
PPPBDBBI_00084 5.1e-110 XK27_02070 S nitroreductase
PPPBDBBI_00085 6.2e-228 yfnA E amino acid
PPPBDBBI_00086 4.8e-25 csbD K CsbD-like
PPPBDBBI_00087 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
PPPBDBBI_00088 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
PPPBDBBI_00089 1.3e-235 brnQ E Component of the transport system for branched-chain amino acids
PPPBDBBI_00090 2.8e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PPPBDBBI_00091 1e-246 norM V Multidrug efflux pump
PPPBDBBI_00092 9.2e-119 pbuX F xanthine permease
PPPBDBBI_00093 3.3e-69 pbuX F xanthine permease
PPPBDBBI_00094 5.9e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PPPBDBBI_00095 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPBDBBI_00096 1e-163 T Histidine kinase
PPPBDBBI_00097 5.8e-135 macB2 V ABC transporter, ATP-binding protein
PPPBDBBI_00098 0.0 V ABC transporter (permease)
PPPBDBBI_00099 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
PPPBDBBI_00100 2.6e-30 liaI KT membrane
PPPBDBBI_00101 1.4e-15 liaI KT membrane
PPPBDBBI_00102 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
PPPBDBBI_00103 3.7e-122 S An automated process has identified a potential problem with this gene model
PPPBDBBI_00105 3.9e-41 3.6.1.55 F NUDIX domain
PPPBDBBI_00106 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
PPPBDBBI_00107 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
PPPBDBBI_00108 2.3e-213 EGP Major facilitator Superfamily
PPPBDBBI_00112 9.7e-158 XK27_09825 V abc transporter atp-binding protein
PPPBDBBI_00113 1.4e-133 yvfS V ABC-2 type transporter
PPPBDBBI_00114 2.6e-192 desK 2.7.13.3 T Histidine kinase
PPPBDBBI_00115 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPPBDBBI_00116 1.1e-98 S transport system, permease component
PPPBDBBI_00117 7.6e-146 S ABC-2 family transporter protein
PPPBDBBI_00118 7.4e-26
PPPBDBBI_00119 4e-102 sdaAA 4.3.1.17 E L-serine dehydratase
PPPBDBBI_00120 6.9e-30 sdaAA 4.3.1.17 E L-serine dehydratase
PPPBDBBI_00121 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
PPPBDBBI_00122 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
PPPBDBBI_00123 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PPPBDBBI_00124 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PPPBDBBI_00125 4e-19 K negative regulation of transcription, DNA-templated
PPPBDBBI_00126 1.7e-23 K negative regulation of transcription, DNA-templated
PPPBDBBI_00128 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
PPPBDBBI_00129 1.8e-88 S Putative adhesin
PPPBDBBI_00130 3.9e-161 XK27_06930 V domain protein
PPPBDBBI_00131 6.4e-96 XK27_06935 K transcriptional regulator
PPPBDBBI_00132 4.8e-55 ypaA M Membrane
PPPBDBBI_00133 2.7e-08
PPPBDBBI_00134 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PPPBDBBI_00135 8.2e-48 veg S Biofilm formation stimulator VEG
PPPBDBBI_00136 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PPPBDBBI_00137 3.9e-70 rplI J binds to the 23S rRNA
PPPBDBBI_00138 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PPPBDBBI_00139 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PPPBDBBI_00140 1.5e-77 F NUDIX domain
PPPBDBBI_00141 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PPPBDBBI_00142 0.0 S Bacterial membrane protein, YfhO
PPPBDBBI_00143 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
PPPBDBBI_00144 3.1e-93 lytE M LysM domain protein
PPPBDBBI_00145 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPPBDBBI_00146 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPPBDBBI_00147 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPPBDBBI_00148 6.9e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PPPBDBBI_00149 3.7e-138 ymfM S sequence-specific DNA binding
PPPBDBBI_00150 1.4e-242 ymfH S Peptidase M16
PPPBDBBI_00151 1.4e-234 ymfF S Peptidase M16
PPPBDBBI_00152 1.2e-43 yaaA S S4 domain protein YaaA
PPPBDBBI_00153 1.7e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PPPBDBBI_00154 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PPPBDBBI_00155 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PPPBDBBI_00156 1.1e-153 yvjA S membrane
PPPBDBBI_00157 6.7e-306 ybiT S abc transporter atp-binding protein
PPPBDBBI_00158 0.0 XK27_10405 S Bacterial membrane protein YfhO
PPPBDBBI_00162 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
PPPBDBBI_00163 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PPPBDBBI_00164 5.3e-194 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PPPBDBBI_00165 1e-134 parB K Belongs to the ParB family
PPPBDBBI_00166 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PPPBDBBI_00167 5.3e-201 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PPPBDBBI_00168 1.1e-29 yyzM S Protein conserved in bacteria
PPPBDBBI_00169 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PPPBDBBI_00170 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PPPBDBBI_00171 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PPPBDBBI_00172 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PPPBDBBI_00173 2.7e-61 divIC D Septum formation initiator
PPPBDBBI_00175 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
PPPBDBBI_00176 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PPPBDBBI_00177 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PPPBDBBI_00178 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PPPBDBBI_00179 1.7e-162 L Transposase
PPPBDBBI_00180 1.5e-92 L Transposase
PPPBDBBI_00181 2.7e-28 L transposition
PPPBDBBI_00182 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
PPPBDBBI_00183 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
PPPBDBBI_00184 3.7e-157 glcU U Glucose uptake
PPPBDBBI_00185 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
PPPBDBBI_00186 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
PPPBDBBI_00187 2.2e-101 XK27_10720 D peptidase activity
PPPBDBBI_00188 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
PPPBDBBI_00189 1.7e-08
PPPBDBBI_00191 1.2e-172 yeiH S Membrane
PPPBDBBI_00192 5.5e-119 mur1 NU muramidase
PPPBDBBI_00193 2.4e-83 L transposition
PPPBDBBI_00194 4.5e-166 cpsY K Transcriptional regulator
PPPBDBBI_00195 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PPPBDBBI_00196 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
PPPBDBBI_00197 2e-104 artQ P ABC transporter (Permease
PPPBDBBI_00198 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPBDBBI_00199 2.5e-158 aatB ET ABC transporter substrate-binding protein
PPPBDBBI_00200 1e-137 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPPBDBBI_00201 2.1e-07
PPPBDBBI_00202 4.1e-26
PPPBDBBI_00203 8.1e-60 adhP 1.1.1.1 C alcohol dehydrogenase
PPPBDBBI_00204 1.7e-17 adhP 1.1.1.1 C alcohol dehydrogenase
PPPBDBBI_00205 7.2e-30 adhP 1.1.1.1 C alcohol dehydrogenase
PPPBDBBI_00206 4.6e-78 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
PPPBDBBI_00207 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PPPBDBBI_00208 2e-126 gntR1 K transcriptional
PPPBDBBI_00209 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PPPBDBBI_00210 2.2e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PPPBDBBI_00211 4.1e-87 niaX
PPPBDBBI_00212 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
PPPBDBBI_00213 1.8e-127 K DNA-binding helix-turn-helix protein
PPPBDBBI_00214 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PPPBDBBI_00215 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PPPBDBBI_00216 8.2e-168 GK ROK family
PPPBDBBI_00217 8.3e-159 dprA LU DNA protecting protein DprA
PPPBDBBI_00218 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PPPBDBBI_00219 1.4e-150 S TraX protein
PPPBDBBI_00220 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPBDBBI_00221 2.4e-251 T PhoQ Sensor
PPPBDBBI_00222 1.5e-258 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PPPBDBBI_00223 1.1e-152 XK27_05470 E Methionine synthase
PPPBDBBI_00224 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PPPBDBBI_00225 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PPPBDBBI_00226 2.4e-37 IQ Acetoin reductase
PPPBDBBI_00227 5.9e-45 IQ Acetoin reductase
PPPBDBBI_00229 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PPPBDBBI_00230 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPBDBBI_00232 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PPPBDBBI_00233 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PPPBDBBI_00234 0.0 dnaE 2.7.7.7 L DNA polymerase
PPPBDBBI_00235 3.2e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
PPPBDBBI_00236 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PPPBDBBI_00237 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PPPBDBBI_00238 2.5e-43 ysdA L Membrane
PPPBDBBI_00239 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PPPBDBBI_00240 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PPPBDBBI_00241 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PPPBDBBI_00242 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PPPBDBBI_00244 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PPPBDBBI_00245 2.1e-84 ypmS S Protein conserved in bacteria
PPPBDBBI_00246 6e-144 ypmR E lipolytic protein G-D-S-L family
PPPBDBBI_00247 1e-148 DegV S DegV family
PPPBDBBI_00248 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
PPPBDBBI_00249 1.8e-72 argR K Regulates arginine biosynthesis genes
PPPBDBBI_00250 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PPPBDBBI_00251 1.5e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PPPBDBBI_00252 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
PPPBDBBI_00253 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PPPBDBBI_00255 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PPPBDBBI_00256 2.9e-125 dnaD
PPPBDBBI_00257 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PPPBDBBI_00258 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PPPBDBBI_00259 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
PPPBDBBI_00260 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PPPBDBBI_00261 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PPPBDBBI_00262 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PPPBDBBI_00263 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PPPBDBBI_00264 5.4e-197 L transposase, IS4 family
PPPBDBBI_00265 5.6e-240 rodA D Belongs to the SEDS family
PPPBDBBI_00266 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
PPPBDBBI_00267 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PPPBDBBI_00268 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PPPBDBBI_00269 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PPPBDBBI_00270 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PPPBDBBI_00271 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PPPBDBBI_00272 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PPPBDBBI_00273 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PPPBDBBI_00274 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PPPBDBBI_00275 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PPPBDBBI_00277 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PPPBDBBI_00278 7.9e-39 ptsH G phosphocarrier protein Hpr
PPPBDBBI_00279 7.4e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
PPPBDBBI_00280 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
PPPBDBBI_00281 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PPPBDBBI_00282 2.2e-34 nrdH O Glutaredoxin
PPPBDBBI_00283 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PPPBDBBI_00284 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PPPBDBBI_00286 4.2e-71 L Transposase (IS116 IS110 IS902 family)
PPPBDBBI_00287 3.3e-26 L Transposase (IS116 IS110 IS902 family)
PPPBDBBI_00288 6.9e-165 ypuA S secreted protein
PPPBDBBI_00289 8.3e-51 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
PPPBDBBI_00290 8.7e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PPPBDBBI_00291 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PPPBDBBI_00292 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PPPBDBBI_00293 3.4e-258 noxE P NADH oxidase
PPPBDBBI_00294 1.9e-294 yfmM S abc transporter atp-binding protein
PPPBDBBI_00295 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
PPPBDBBI_00296 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PPPBDBBI_00297 4.5e-44 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PPPBDBBI_00298 2e-86 S ECF-type riboflavin transporter, S component
PPPBDBBI_00300 5e-240 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PPPBDBBI_00301 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
PPPBDBBI_00304 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PPPBDBBI_00305 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPPBDBBI_00306 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PPPBDBBI_00307 0.0 smc D Required for chromosome condensation and partitioning
PPPBDBBI_00308 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PPPBDBBI_00309 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PPPBDBBI_00310 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PPPBDBBI_00311 2.4e-92 pat 2.3.1.183 M acetyltransferase
PPPBDBBI_00312 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PPPBDBBI_00313 4.2e-62 manO S protein conserved in bacteria
PPPBDBBI_00314 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
PPPBDBBI_00315 1.7e-116 manM G pts system
PPPBDBBI_00316 2.8e-174 manL 2.7.1.191 G pts system
PPPBDBBI_00317 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
PPPBDBBI_00318 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PPPBDBBI_00319 2.1e-247 pbuO S permease
PPPBDBBI_00320 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
PPPBDBBI_00321 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
PPPBDBBI_00322 2.5e-220 brpA K Transcriptional
PPPBDBBI_00323 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
PPPBDBBI_00324 3.1e-212 nusA K Participates in both transcription termination and antitermination
PPPBDBBI_00325 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
PPPBDBBI_00326 1.4e-41 ylxQ J ribosomal protein
PPPBDBBI_00327 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PPPBDBBI_00328 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PPPBDBBI_00329 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
PPPBDBBI_00330 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
PPPBDBBI_00331 2.1e-213 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PPPBDBBI_00332 1.4e-275 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PPPBDBBI_00333 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
PPPBDBBI_00334 3.6e-95 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
PPPBDBBI_00335 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
PPPBDBBI_00336 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PPPBDBBI_00338 1.4e-09 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
PPPBDBBI_00339 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PPPBDBBI_00340 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PPPBDBBI_00341 3.4e-74 ylbF S Belongs to the UPF0342 family
PPPBDBBI_00342 7.1e-46 ylbG S UPF0298 protein
PPPBDBBI_00343 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PPPBDBBI_00344 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
PPPBDBBI_00345 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
PPPBDBBI_00346 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PPPBDBBI_00347 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PPPBDBBI_00348 2.8e-70 acuB S IMP dehydrogenase activity
PPPBDBBI_00349 3.3e-43 acuB S IMP dehydrogenase activity
PPPBDBBI_00350 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PPPBDBBI_00351 6.3e-111 yvyE 3.4.13.9 S YigZ family
PPPBDBBI_00352 1.7e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PPPBDBBI_00353 4.4e-123 comFC S Competence protein
PPPBDBBI_00354 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PPPBDBBI_00355 5.8e-169 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PPPBDBBI_00356 2.9e-218 araT 2.6.1.1 E Aminotransferase
PPPBDBBI_00357 7e-144 recO L Involved in DNA repair and RecF pathway recombination
PPPBDBBI_00358 9.6e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PPPBDBBI_00359 9.3e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PPPBDBBI_00360 9.9e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PPPBDBBI_00361 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PPPBDBBI_00362 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PPPBDBBI_00363 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PPPBDBBI_00364 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PPPBDBBI_00365 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PPPBDBBI_00366 1e-90 L transposase activity
PPPBDBBI_00367 3.5e-50 L transposition
PPPBDBBI_00368 2e-32 L Integrase core domain protein
PPPBDBBI_00369 2.3e-161 S CHAP domain
PPPBDBBI_00370 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
PPPBDBBI_00371 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PPPBDBBI_00372 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PPPBDBBI_00373 9.2e-141 1.1.1.169 H Ketopantoate reductase
PPPBDBBI_00374 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PPPBDBBI_00375 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PPPBDBBI_00376 8.2e-70 argR K Regulates arginine biosynthesis genes
PPPBDBBI_00377 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PPPBDBBI_00378 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PPPBDBBI_00379 7e-34 S Protein of unknown function (DUF3021)
PPPBDBBI_00380 1.2e-61 KT phosphorelay signal transduction system
PPPBDBBI_00382 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PPPBDBBI_00384 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PPPBDBBI_00385 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
PPPBDBBI_00386 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
PPPBDBBI_00387 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PPPBDBBI_00388 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
PPPBDBBI_00389 3.4e-13 nudL L hydrolase
PPPBDBBI_00390 7.2e-95 nudL L hydrolase
PPPBDBBI_00391 4.9e-12 K CsbD-like
PPPBDBBI_00392 4.3e-71 M Protein conserved in bacteria
PPPBDBBI_00393 1.8e-23 S Small integral membrane protein
PPPBDBBI_00394 3.1e-101
PPPBDBBI_00395 3.7e-27 S Membrane
PPPBDBBI_00397 2.7e-95 S Hydrophobic domain protein
PPPBDBBI_00398 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
PPPBDBBI_00400 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PPPBDBBI_00401 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PPPBDBBI_00402 9.2e-36 metE 2.1.1.14 E Methionine synthase
PPPBDBBI_00403 7.6e-64 metE 2.1.1.14 E Methionine synthase
PPPBDBBI_00404 5.7e-52 metE 2.1.1.14 E Methionine synthase
PPPBDBBI_00405 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
PPPBDBBI_00407 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PPPBDBBI_00408 9.9e-169 XK27_01785 S cog cog1284
PPPBDBBI_00409 1.8e-147 yaaA S Belongs to the UPF0246 family
PPPBDBBI_00410 1.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PPPBDBBI_00411 2.6e-91 XK27_10930 K acetyltransferase
PPPBDBBI_00412 7.5e-14
PPPBDBBI_00413 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PPPBDBBI_00414 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
PPPBDBBI_00415 4.2e-44 yrzB S Belongs to the UPF0473 family
PPPBDBBI_00416 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PPPBDBBI_00417 2.8e-44 yrzL S Belongs to the UPF0297 family
PPPBDBBI_00418 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PPPBDBBI_00419 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
PPPBDBBI_00421 3.5e-216 int L Belongs to the 'phage' integrase family
PPPBDBBI_00422 1.9e-18 S Domain of unknown function (DUF3173)
PPPBDBBI_00423 1.4e-107 L Replication initiation factor
PPPBDBBI_00424 1e-36 L Replication initiation factor
PPPBDBBI_00425 3.1e-14 K Cro/C1-type HTH DNA-binding domain
PPPBDBBI_00426 1.3e-60 K sequence-specific DNA binding
PPPBDBBI_00427 3.9e-287 V ABC transporter transmembrane region
PPPBDBBI_00428 3.4e-191 C Radical SAM
PPPBDBBI_00429 6.3e-16 C Radical SAM
PPPBDBBI_00431 1.4e-127 Z012_04635 K sequence-specific DNA binding
PPPBDBBI_00432 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPBDBBI_00433 2.1e-280 V ABC transporter
PPPBDBBI_00434 0.0 KLT serine threonine protein kinase
PPPBDBBI_00435 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPBDBBI_00437 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
PPPBDBBI_00438 3.1e-172 yxaM EGP Major facilitator Superfamily
PPPBDBBI_00439 8.8e-83 adk 2.7.4.3 F topology modulation protein
PPPBDBBI_00440 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PPPBDBBI_00441 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PPPBDBBI_00442 1.7e-35 XK27_09805 S MORN repeat protein
PPPBDBBI_00443 0.0 XK27_09800 I Acyltransferase
PPPBDBBI_00444 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PPPBDBBI_00445 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PPPBDBBI_00446 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PPPBDBBI_00447 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
PPPBDBBI_00448 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PPPBDBBI_00449 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PPPBDBBI_00450 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PPPBDBBI_00451 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PPPBDBBI_00452 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PPPBDBBI_00453 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PPPBDBBI_00454 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
PPPBDBBI_00455 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PPPBDBBI_00456 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PPPBDBBI_00457 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PPPBDBBI_00458 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PPPBDBBI_00459 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PPPBDBBI_00460 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PPPBDBBI_00461 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PPPBDBBI_00462 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PPPBDBBI_00463 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PPPBDBBI_00464 2.5e-23 rpmD J ribosomal protein l30
PPPBDBBI_00465 4.4e-58 rplO J binds to the 23S rRNA
PPPBDBBI_00466 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PPPBDBBI_00467 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PPPBDBBI_00468 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PPPBDBBI_00469 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PPPBDBBI_00470 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PPPBDBBI_00471 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PPPBDBBI_00472 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPPBDBBI_00473 3.3e-62 rplQ J ribosomal protein l17
PPPBDBBI_00474 1.8e-111 L PFAM Integrase, catalytic core
PPPBDBBI_00475 3.3e-09 L PFAM Integrase, catalytic core
PPPBDBBI_00476 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
PPPBDBBI_00477 3.6e-64 6.3.2.2 H gamma-glutamylcysteine synthetase
PPPBDBBI_00478 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
PPPBDBBI_00480 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
PPPBDBBI_00481 1e-140 L DNA integration
PPPBDBBI_00482 6.7e-98 blpT
PPPBDBBI_00483 2.9e-28 blpT
PPPBDBBI_00484 3e-47 spiA K sequence-specific DNA binding
PPPBDBBI_00487 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PPPBDBBI_00488 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PPPBDBBI_00489 5e-44 V CAAX protease self-immunity
PPPBDBBI_00490 4.6e-140 cppA E CppA N-terminal
PPPBDBBI_00491 6.5e-184 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
PPPBDBBI_00492 3.6e-117 ybbL S abc transporter atp-binding protein
PPPBDBBI_00493 1.5e-127 ybbM S transport system, permease component
PPPBDBBI_00494 2.9e-87 D nuclear chromosome segregation
PPPBDBBI_00495 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
PPPBDBBI_00496 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPPBDBBI_00497 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
PPPBDBBI_00498 0.0 pflB 2.3.1.54 C formate acetyltransferase'
PPPBDBBI_00499 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPPBDBBI_00501 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PPPBDBBI_00502 4.7e-163 yxeN P ABC transporter (Permease
PPPBDBBI_00503 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
PPPBDBBI_00504 3.2e-09 S Protein of unknown function (DUF4059)
PPPBDBBI_00505 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PPPBDBBI_00506 2.5e-92 rsmD 2.1.1.171 L Methyltransferase
PPPBDBBI_00507 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PPPBDBBI_00508 2.2e-196 ylbL T Belongs to the peptidase S16 family
PPPBDBBI_00509 1.3e-184 yhcC S radical SAM protein
PPPBDBBI_00510 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
PPPBDBBI_00512 0.0 yjcE P NhaP-type Na H and K H antiporters
PPPBDBBI_00513 1.2e-143 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
PPPBDBBI_00514 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
PPPBDBBI_00515 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PPPBDBBI_00518 2.4e-75 XK27_03180 T universal stress protein
PPPBDBBI_00519 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
PPPBDBBI_00520 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PPPBDBBI_00521 6.8e-101 pncA Q isochorismatase
PPPBDBBI_00522 4.8e-154 hlpA M Belongs to the NlpA lipoprotein family
PPPBDBBI_00523 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PPPBDBBI_00524 4.4e-255 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPPBDBBI_00525 6.3e-31 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PPPBDBBI_00526 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PPPBDBBI_00527 3.5e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PPPBDBBI_00528 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PPPBDBBI_00529 1.3e-57
PPPBDBBI_00530 2.6e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PPPBDBBI_00531 1.8e-98 yqeG S hydrolase of the HAD superfamily
PPPBDBBI_00532 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PPPBDBBI_00533 3.5e-49 yhbY J RNA-binding protein
PPPBDBBI_00534 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PPPBDBBI_00535 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PPPBDBBI_00536 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PPPBDBBI_00537 2e-140 yqeM Q Methyltransferase domain protein
PPPBDBBI_00538 6.9e-206 ylbM S Belongs to the UPF0348 family
PPPBDBBI_00539 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
PPPBDBBI_00540 7.3e-107
PPPBDBBI_00541 2.6e-55 S CD20-like family
PPPBDBBI_00542 5.6e-12
PPPBDBBI_00543 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PPPBDBBI_00544 2.3e-133 ecsA V abc transporter atp-binding protein
PPPBDBBI_00545 2.7e-183 ecsB U ABC transporter
PPPBDBBI_00546 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
PPPBDBBI_00547 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PPPBDBBI_00549 7.7e-227 ytfP S Flavoprotein
PPPBDBBI_00550 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PPPBDBBI_00551 4.8e-63 XK27_02560 S cog cog2151
PPPBDBBI_00552 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
PPPBDBBI_00553 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
PPPBDBBI_00554 2.7e-129 K transcriptional regulator, MerR family
PPPBDBBI_00555 9.7e-28 L transposase activity
PPPBDBBI_00556 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PPPBDBBI_00557 3.9e-26
PPPBDBBI_00558 0.0 ctpE P E1-E2 ATPase
PPPBDBBI_00559 1.7e-51
PPPBDBBI_00560 8.1e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
PPPBDBBI_00561 6.9e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PPPBDBBI_00562 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
PPPBDBBI_00563 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PPPBDBBI_00564 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PPPBDBBI_00565 8.8e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
PPPBDBBI_00566 5.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PPPBDBBI_00567 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PPPBDBBI_00568 2.7e-73 copY K Copper transport repressor, CopY TcrY family
PPPBDBBI_00569 0.0 copA 3.6.3.54 P P-type ATPase
PPPBDBBI_00570 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
PPPBDBBI_00571 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PPPBDBBI_00572 1e-114 papP P ABC transporter (Permease
PPPBDBBI_00573 1.3e-114 P ABC transporter (Permease
PPPBDBBI_00574 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPBDBBI_00575 1.1e-155 cjaA ET ABC transporter substrate-binding protein
PPPBDBBI_00579 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PPPBDBBI_00580 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
PPPBDBBI_00581 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PPPBDBBI_00582 1.9e-201 yjbB G Permeases of the major facilitator superfamily
PPPBDBBI_00583 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PPPBDBBI_00584 7.8e-100 thiT S Thiamine transporter
PPPBDBBI_00585 1.9e-62 yjqA S Bacterial PH domain
PPPBDBBI_00586 6.7e-154 corA P CorA-like protein
PPPBDBBI_00587 6.9e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PPPBDBBI_00588 1e-41 yazA L endonuclease containing a URI domain
PPPBDBBI_00589 7.1e-141 yabB 2.1.1.223 L Methyltransferase
PPPBDBBI_00590 1.8e-140 nodB3 G deacetylase
PPPBDBBI_00591 1.7e-142 plsC 2.3.1.51 I Acyltransferase
PPPBDBBI_00592 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PPPBDBBI_00593 0.0 comEC S Competence protein ComEC
PPPBDBBI_00594 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PPPBDBBI_00595 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
PPPBDBBI_00596 3.3e-231 ytoI K transcriptional regulator containing CBS domains
PPPBDBBI_00597 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PPPBDBBI_00598 4.9e-160 rbn E Belongs to the UPF0761 family
PPPBDBBI_00599 3.7e-85 ccl S cog cog4708
PPPBDBBI_00600 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PPPBDBBI_00601 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PPPBDBBI_00602 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
PPPBDBBI_00603 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
PPPBDBBI_00604 2.1e-74 S QueT transporter
PPPBDBBI_00605 2.6e-157 xth 3.1.11.2 L exodeoxyribonuclease III
PPPBDBBI_00606 2e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
PPPBDBBI_00607 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PPPBDBBI_00608 4.1e-37 ylqC L Belongs to the UPF0109 family
PPPBDBBI_00609 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PPPBDBBI_00610 0.0 ydaO E amino acid
PPPBDBBI_00611 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
PPPBDBBI_00612 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PPPBDBBI_00613 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PPPBDBBI_00614 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PPPBDBBI_00615 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PPPBDBBI_00616 7.8e-171 murB 1.3.1.98 M cell wall formation
PPPBDBBI_00617 6.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PPPBDBBI_00618 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
PPPBDBBI_00619 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
PPPBDBBI_00620 2.3e-206 potD P spermidine putrescine ABC transporter
PPPBDBBI_00621 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
PPPBDBBI_00622 5.1e-47 XK27_08050 O stress-induced mitochondrial fusion
PPPBDBBI_00623 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
PPPBDBBI_00624 5.1e-96 GK ROK family
PPPBDBBI_00625 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PPPBDBBI_00626 3.9e-104 wecD M Acetyltransferase GNAT family
PPPBDBBI_00627 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PPPBDBBI_00628 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
PPPBDBBI_00629 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
PPPBDBBI_00631 7.7e-56 lrgA S Effector of murein hydrolase LrgA
PPPBDBBI_00632 2.5e-116 lrgB M effector of murein hydrolase
PPPBDBBI_00633 2.6e-109 3.1.3.18 S IA, variant 1
PPPBDBBI_00634 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PPPBDBBI_00635 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PPPBDBBI_00636 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
PPPBDBBI_00637 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PPPBDBBI_00638 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPBDBBI_00639 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPBDBBI_00640 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
PPPBDBBI_00642 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
PPPBDBBI_00644 6.6e-30 ycaO O OsmC-like protein
PPPBDBBI_00645 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
PPPBDBBI_00648 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPPBDBBI_00650 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PPPBDBBI_00651 1.1e-16 XK27_00735
PPPBDBBI_00652 1.8e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPBDBBI_00653 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
PPPBDBBI_00654 7.6e-32 S CAAX amino terminal protease family protein
PPPBDBBI_00655 1.2e-55 V CAAX protease self-immunity
PPPBDBBI_00657 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PPPBDBBI_00658 2.9e-84 mutT 3.6.1.55 F Nudix family
PPPBDBBI_00659 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
PPPBDBBI_00660 9.4e-136 ET ABC transporter
PPPBDBBI_00661 4e-201 arcT 2.6.1.1 E Aminotransferase
PPPBDBBI_00662 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
PPPBDBBI_00663 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PPPBDBBI_00664 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PPPBDBBI_00665 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PPPBDBBI_00666 1.3e-54 yitW K metal-sulfur cluster biosynthetic enzyme
PPPBDBBI_00667 4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PPPBDBBI_00668 4.1e-245
PPPBDBBI_00669 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PPPBDBBI_00670 1.9e-124 ycbB S Glycosyl transferase family 2
PPPBDBBI_00671 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
PPPBDBBI_00672 1.8e-213 amrA S polysaccharide biosynthetic process
PPPBDBBI_00673 1.6e-127 2.7.8.12 M transferase activity, transferring glycosyl groups
PPPBDBBI_00674 6e-139 S Predicted membrane protein (DUF2142)
PPPBDBBI_00675 1.2e-224 rgpA GT4 M Domain of unknown function (DUF1972)
PPPBDBBI_00676 1.4e-178 rgpB GT2 M Glycosyltransferase, group 2 family protein
PPPBDBBI_00677 1.4e-142 rgpC GM Transport permease protein
PPPBDBBI_00678 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PPPBDBBI_00679 1.1e-179 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PPPBDBBI_00680 0.0 rgpF M Rhamnan synthesis protein F
PPPBDBBI_00681 2.4e-119 radC E Belongs to the UPF0758 family
PPPBDBBI_00682 3.9e-130 puuD T peptidase C26
PPPBDBBI_00683 1.5e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PPPBDBBI_00684 2e-58 XK27_04120 S Putative amino acid metabolism
PPPBDBBI_00685 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
PPPBDBBI_00686 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PPPBDBBI_00687 1.5e-103 yjbK S Adenylate cyclase
PPPBDBBI_00688 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
PPPBDBBI_00689 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PPPBDBBI_00690 8.3e-173 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PPPBDBBI_00691 1.4e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PPPBDBBI_00692 7.2e-66 L Transposase
PPPBDBBI_00693 1e-94 L Integrase core domain protein
PPPBDBBI_00694 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
PPPBDBBI_00695 1.4e-40 tatD L Hydrolase, tatd
PPPBDBBI_00696 3.8e-45 oppF P Belongs to the ABC transporter superfamily
PPPBDBBI_00697 1.2e-24 oppF P Belongs to the ABC transporter superfamily
PPPBDBBI_00698 4.1e-158 L COG2801 Transposase and inactivated derivatives
PPPBDBBI_00699 8.1e-45 L Transposase
PPPBDBBI_00700 1.5e-37 L transposase activity
PPPBDBBI_00701 3.2e-66 L COG2801 Transposase and inactivated derivatives
PPPBDBBI_00702 1.2e-73 L COG2801 Transposase and inactivated derivatives
PPPBDBBI_00703 8.9e-11
PPPBDBBI_00704 7.8e-59 S Protein of unknown function (DUF1722)
PPPBDBBI_00705 3.3e-64 yqeB S Pyrimidine dimer DNA glycosylase
PPPBDBBI_00707 1.2e-32
PPPBDBBI_00708 1.7e-26 S CAAX protease self-immunity
PPPBDBBI_00709 5.5e-42 S CAAX protease self-immunity
PPPBDBBI_00710 5.6e-27 estA E GDSL-like Lipase/Acylhydrolase
PPPBDBBI_00711 2.1e-95
PPPBDBBI_00712 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PPPBDBBI_00713 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPBDBBI_00714 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPBDBBI_00715 1e-185 S CRISPR-associated protein Csn2 subfamily St
PPPBDBBI_00716 2.7e-146 ycgQ S TIGR03943 family
PPPBDBBI_00717 1.2e-155 XK27_03015 S permease
PPPBDBBI_00719 0.0 yhgF K Transcriptional accessory protein
PPPBDBBI_00720 9.9e-42 pspC KT PspC domain
PPPBDBBI_00721 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PPPBDBBI_00722 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PPPBDBBI_00724 5.5e-69 ytxH S General stress protein
PPPBDBBI_00726 2e-177 yegQ O Peptidase U32
PPPBDBBI_00727 3.4e-252 yegQ O Peptidase U32
PPPBDBBI_00728 8.1e-46 S CHY zinc finger
PPPBDBBI_00729 1.5e-35 K sequence-specific DNA binding
PPPBDBBI_00731 0.0 S Lantibiotic dehydratase, C terminus
PPPBDBBI_00732 1.6e-230 spaC2 V Lanthionine synthetase C family protein
PPPBDBBI_00733 3.3e-183 EGP Major facilitator Superfamily
PPPBDBBI_00734 1.6e-91 3.6.4.12 K Divergent AAA domain protein
PPPBDBBI_00735 4.8e-51 int L Belongs to the 'phage' integrase family
PPPBDBBI_00736 6.6e-105 int L Belongs to the 'phage' integrase family
PPPBDBBI_00737 2.8e-39 S Helix-turn-helix domain
PPPBDBBI_00738 4.9e-173
PPPBDBBI_00740 3.4e-75 isp2 S pathogenesis
PPPBDBBI_00741 2.2e-90 tnp L Transposase
PPPBDBBI_00742 3.3e-225 capA M Bacterial capsule synthesis protein
PPPBDBBI_00743 3.6e-39 gcvR T UPF0237 protein
PPPBDBBI_00744 1.9e-242 XK27_08635 S UPF0210 protein
PPPBDBBI_00745 8.3e-38 ais G alpha-ribazole phosphatase activity
PPPBDBBI_00746 7.9e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PPPBDBBI_00747 7.2e-101 acmA 3.2.1.17 NU amidase activity
PPPBDBBI_00748 5.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PPPBDBBI_00749 1.9e-69 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PPPBDBBI_00750 8.4e-281 dnaK O Heat shock 70 kDa protein
PPPBDBBI_00751 5.6e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PPPBDBBI_00752 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PPPBDBBI_00753 1.4e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
PPPBDBBI_00754 3.3e-72 hmpT S cog cog4720
PPPBDBBI_00755 3.6e-88 T PhoQ Sensor
PPPBDBBI_00756 2.2e-43 T PhoQ Sensor
PPPBDBBI_00757 2.8e-40 T PhoQ Sensor
PPPBDBBI_00758 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPBDBBI_00759 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PPPBDBBI_00760 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
PPPBDBBI_00761 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PPPBDBBI_00762 1.7e-94 panT S ECF transporter, substrate-specific component
PPPBDBBI_00763 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PPPBDBBI_00764 7.3e-166 metF 1.5.1.20 E reductase
PPPBDBBI_00765 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PPPBDBBI_00767 6.9e-220 sip L Belongs to the 'phage' integrase family
PPPBDBBI_00768 1e-21 xre K transcriptional
PPPBDBBI_00769 1.8e-19 K Cro/C1-type HTH DNA-binding domain
PPPBDBBI_00773 3.1e-22
PPPBDBBI_00774 1.2e-149 KL Phage plasmid primase P4 family
PPPBDBBI_00775 1.4e-289 S DNA primase
PPPBDBBI_00777 2.9e-12
PPPBDBBI_00779 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
PPPBDBBI_00780 0.0 3.6.3.8 P cation transport ATPase
PPPBDBBI_00782 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
PPPBDBBI_00783 3.5e-79 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
PPPBDBBI_00786 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
PPPBDBBI_00787 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PPPBDBBI_00788 1.1e-83 S Putative small multi-drug export protein
PPPBDBBI_00789 6.2e-76 ctsR K Belongs to the CtsR family
PPPBDBBI_00790 0.0 clpC O Belongs to the ClpA ClpB family
PPPBDBBI_00791 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PPPBDBBI_00792 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PPPBDBBI_00793 1.2e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PPPBDBBI_00794 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PPPBDBBI_00795 2e-143 S SseB protein N-terminal domain
PPPBDBBI_00796 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
PPPBDBBI_00797 3.9e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPPBDBBI_00798 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PPPBDBBI_00801 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PPPBDBBI_00802 3.5e-91 yacP S RNA-binding protein containing a PIN domain
PPPBDBBI_00803 3.4e-155 degV S DegV family
PPPBDBBI_00804 1.8e-31 K helix-turn-helix
PPPBDBBI_00805 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PPPBDBBI_00806 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PPPBDBBI_00807 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PPPBDBBI_00808 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PPPBDBBI_00809 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PPPBDBBI_00810 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PPPBDBBI_00811 9e-206 yurR 1.4.5.1 E oxidoreductase
PPPBDBBI_00812 6.4e-29 zupT P transporter
PPPBDBBI_00813 1.1e-13 zupT P Mediates zinc uptake. May also transport other divalent cations
PPPBDBBI_00814 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PPPBDBBI_00815 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
PPPBDBBI_00816 1.7e-70 gtrA S GtrA-like protein
PPPBDBBI_00817 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PPPBDBBI_00818 6e-169 ybbR S Protein conserved in bacteria
PPPBDBBI_00819 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PPPBDBBI_00820 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
PPPBDBBI_00821 8.7e-150 cobQ S glutamine amidotransferase
PPPBDBBI_00822 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PPPBDBBI_00823 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
PPPBDBBI_00824 0.0 uup S abc transporter atp-binding protein
PPPBDBBI_00825 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
PPPBDBBI_00826 2.7e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
PPPBDBBI_00827 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PPPBDBBI_00828 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PPPBDBBI_00830 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PPPBDBBI_00831 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PPPBDBBI_00832 3.1e-81 ypmB S Protein conserved in bacteria
PPPBDBBI_00833 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PPPBDBBI_00834 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PPPBDBBI_00835 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
PPPBDBBI_00836 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
PPPBDBBI_00837 8.3e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PPPBDBBI_00838 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
PPPBDBBI_00839 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PPPBDBBI_00840 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PPPBDBBI_00841 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PPPBDBBI_00842 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PPPBDBBI_00843 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PPPBDBBI_00844 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
PPPBDBBI_00845 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
PPPBDBBI_00846 2.1e-30 rpsT J rRNA binding
PPPBDBBI_00847 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PPPBDBBI_00848 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PPPBDBBI_00849 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PPPBDBBI_00850 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PPPBDBBI_00851 1.1e-142 purR 2.4.2.7 F operon repressor
PPPBDBBI_00852 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
PPPBDBBI_00853 6.9e-173 rmuC S RmuC domain protein
PPPBDBBI_00854 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
PPPBDBBI_00855 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PPPBDBBI_00856 6.4e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PPPBDBBI_00858 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PPPBDBBI_00859 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PPPBDBBI_00860 4.1e-144 tatD L Hydrolase, tatd
PPPBDBBI_00861 1.9e-74 yccU S CoA-binding protein
PPPBDBBI_00862 4.8e-51 trxA O Belongs to the thioredoxin family
PPPBDBBI_00863 1.9e-141 S Macro domain protein
PPPBDBBI_00864 2e-09 L thioesterase
PPPBDBBI_00865 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
PPPBDBBI_00870 1.8e-167 fhuR K transcriptional regulator (lysR family)
PPPBDBBI_00871 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PPPBDBBI_00872 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PPPBDBBI_00873 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PPPBDBBI_00874 4.9e-227 pyrP F uracil Permease
PPPBDBBI_00875 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PPPBDBBI_00876 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
PPPBDBBI_00877 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
PPPBDBBI_00878 3.1e-87 L Phage integrase family
PPPBDBBI_00879 5.7e-46 S Domain of unknown function (DUF4298)
PPPBDBBI_00880 4.5e-61 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
PPPBDBBI_00881 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PPPBDBBI_00882 3.9e-141 3.1.21.3 V Type I restriction modification DNA specificity domain
PPPBDBBI_00883 2.4e-300 hsdM 2.1.1.72 V HsdM N-terminal domain
PPPBDBBI_00884 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PPPBDBBI_00885 8.2e-205 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PPPBDBBI_00886 2.4e-26
PPPBDBBI_00887 8e-42 K Cold-Shock Protein
PPPBDBBI_00888 5.4e-32 cspD K Cold shock protein domain
PPPBDBBI_00889 6.4e-168 pepD E Dipeptidase
PPPBDBBI_00890 8.7e-162 whiA K May be required for sporulation
PPPBDBBI_00891 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PPPBDBBI_00892 1.2e-163 rapZ S Displays ATPase and GTPase activities
PPPBDBBI_00893 2.8e-137 yejC S cyclic nucleotide-binding protein
PPPBDBBI_00894 4.2e-18 D nuclear chromosome segregation
PPPBDBBI_00895 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PPPBDBBI_00896 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PPPBDBBI_00897 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
PPPBDBBI_00898 4.4e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PPPBDBBI_00899 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
PPPBDBBI_00900 1.2e-34
PPPBDBBI_00902 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PPPBDBBI_00903 4.4e-166 dnaI L Primosomal protein DnaI
PPPBDBBI_00904 6.5e-218 dnaB L Replication initiation and membrane attachment
PPPBDBBI_00905 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PPPBDBBI_00906 2.8e-282 T PhoQ Sensor
PPPBDBBI_00907 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPBDBBI_00908 2.4e-90 yceD K metal-binding, possibly nucleic acid-binding protein
PPPBDBBI_00909 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
PPPBDBBI_00910 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
PPPBDBBI_00911 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
PPPBDBBI_00912 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
PPPBDBBI_00913 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PPPBDBBI_00914 1.2e-149 cbiQ P cobalt transport
PPPBDBBI_00915 0.0 ykoD P abc transporter atp-binding protein
PPPBDBBI_00916 8e-94 S UPF0397 protein
PPPBDBBI_00917 5.5e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
PPPBDBBI_00918 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PPPBDBBI_00919 5.2e-98 metI P ABC transporter (Permease
PPPBDBBI_00920 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PPPBDBBI_00921 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
PPPBDBBI_00922 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
PPPBDBBI_00923 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PPPBDBBI_00924 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
PPPBDBBI_00925 4e-153 ET amino acid transport
PPPBDBBI_00926 3.8e-205 EGP Transmembrane secretion effector
PPPBDBBI_00927 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
PPPBDBBI_00928 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPPBDBBI_00929 5.3e-153 ET amino acid transport
PPPBDBBI_00930 1.6e-131 cbiO P ABC transporter
PPPBDBBI_00931 1.7e-137 P cobalt transport protein
PPPBDBBI_00932 2.7e-177 cbiM P PDGLE domain
PPPBDBBI_00933 4.9e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PPPBDBBI_00934 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PPPBDBBI_00935 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PPPBDBBI_00936 6.6e-78 ureE O enzyme active site formation
PPPBDBBI_00937 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PPPBDBBI_00938 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PPPBDBBI_00939 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PPPBDBBI_00940 1.2e-94 ureI S AmiS/UreI family transporter
PPPBDBBI_00941 1e-55 S Domain of unknown function (DUF4173)
PPPBDBBI_00942 2.6e-47 yhaI L Membrane
PPPBDBBI_00943 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PPPBDBBI_00944 1.8e-27 comA V protein secretion by the type I secretion system
PPPBDBBI_00945 1.1e-34 V protein secretion by the type I secretion system
PPPBDBBI_00946 4.3e-57 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PPPBDBBI_00947 7.4e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PPPBDBBI_00948 1.2e-32 V protein secretion by the type I secretion system
PPPBDBBI_00949 5.6e-161 K sequence-specific DNA binding
PPPBDBBI_00950 4.8e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
PPPBDBBI_00951 1.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PPPBDBBI_00952 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PPPBDBBI_00953 1.4e-245 trkA P Potassium transporter peripheral membrane component
PPPBDBBI_00954 4.8e-255 trkH P Cation transport protein
PPPBDBBI_00955 1.8e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PPPBDBBI_00956 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPPBDBBI_00957 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PPPBDBBI_00958 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PPPBDBBI_00959 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PPPBDBBI_00960 7.8e-85 ykuL S CBS domain
PPPBDBBI_00961 3.5e-99 XK27_09740 S Phosphoesterase
PPPBDBBI_00962 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PPPBDBBI_00963 3.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PPPBDBBI_00964 7.6e-36 yneF S UPF0154 protein
PPPBDBBI_00965 3.7e-91 K transcriptional regulator
PPPBDBBI_00966 9.6e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PPPBDBBI_00969 3.3e-97 ybhL S Belongs to the BI1 family
PPPBDBBI_00970 4.6e-88 XK27_09705 6.1.1.14 S HD superfamily hydrolase
PPPBDBBI_00971 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PPPBDBBI_00972 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PPPBDBBI_00973 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PPPBDBBI_00974 7.5e-58 L Integrase core domain protein
PPPBDBBI_00975 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PPPBDBBI_00976 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PPPBDBBI_00977 7.3e-80 XK27_09675 K -acetyltransferase
PPPBDBBI_00978 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PPPBDBBI_00979 2.5e-23
PPPBDBBI_00980 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
PPPBDBBI_00981 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PPPBDBBI_00982 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PPPBDBBI_00983 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PPPBDBBI_00984 3.1e-95 ypsA S Belongs to the UPF0398 family
PPPBDBBI_00985 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PPPBDBBI_00986 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PPPBDBBI_00987 1.7e-259 pepC 3.4.22.40 E aminopeptidase
PPPBDBBI_00988 3.2e-77 yhaI L Membrane
PPPBDBBI_00989 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PPPBDBBI_00990 8.2e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PPPBDBBI_00991 1.1e-65 S COG1073 Hydrolases of the alpha beta superfamily
PPPBDBBI_00992 6.5e-67 S COG1073 Hydrolases of the alpha beta superfamily
PPPBDBBI_00993 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
PPPBDBBI_00994 3.8e-40 K transcriptional
PPPBDBBI_00995 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPPBDBBI_00996 1.6e-137 glcR K transcriptional regulator (DeoR family)
PPPBDBBI_00997 6.2e-35 cof Q phosphatase activity
PPPBDBBI_00998 6e-55 cof Q phosphatase activity
PPPBDBBI_00999 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
PPPBDBBI_01000 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
PPPBDBBI_01001 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
PPPBDBBI_01002 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PPPBDBBI_01003 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PPPBDBBI_01004 6.8e-56 S TM2 domain
PPPBDBBI_01005 4.7e-43
PPPBDBBI_01008 8.8e-27 L Integrase core domain protein
PPPBDBBI_01009 6.4e-18 L transposase activity
PPPBDBBI_01010 4.4e-37 L Transposase
PPPBDBBI_01011 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PPPBDBBI_01012 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PPPBDBBI_01013 5.2e-142 cmpC S abc transporter atp-binding protein
PPPBDBBI_01014 0.0 WQ51_06230 S ABC transporter substrate binding protein
PPPBDBBI_01015 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PPPBDBBI_01016 7.2e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PPPBDBBI_01017 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
PPPBDBBI_01018 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PPPBDBBI_01019 9.8e-50 yajC U protein transport
PPPBDBBI_01020 1.9e-127 yeeN K transcriptional regulatory protein
PPPBDBBI_01021 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
PPPBDBBI_01022 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
PPPBDBBI_01023 3.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PPPBDBBI_01024 2.1e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
PPPBDBBI_01025 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
PPPBDBBI_01026 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PPPBDBBI_01027 1.6e-127 adcB P ABC transporter (Permease
PPPBDBBI_01028 2.2e-136 adcC P ABC transporter, ATP-binding protein
PPPBDBBI_01029 3.1e-72 adcR K transcriptional
PPPBDBBI_01030 1.9e-223 EGP Major facilitator Superfamily
PPPBDBBI_01031 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PPPBDBBI_01032 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PPPBDBBI_01033 6.4e-23
PPPBDBBI_01034 3.4e-62 oppF P Belongs to the ABC transporter superfamily
PPPBDBBI_01035 7.5e-62 oppF P Belongs to the ABC transporter superfamily
PPPBDBBI_01036 7e-43 oppD P Belongs to the ABC transporter superfamily
PPPBDBBI_01037 1.2e-62 oppD P Belongs to the ABC transporter superfamily
PPPBDBBI_01038 2.5e-32 oppD P Belongs to the ABC transporter superfamily
PPPBDBBI_01039 3e-27 oppD P Belongs to the ABC transporter superfamily
PPPBDBBI_01040 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPPBDBBI_01041 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPPBDBBI_01042 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPPBDBBI_01043 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPPBDBBI_01044 2e-138 oppA E ABC transporter substrate-binding protein
PPPBDBBI_01045 7e-10 oppA E ABC transporter substrate-binding protein
PPPBDBBI_01046 3.5e-274 sufB O assembly protein SufB
PPPBDBBI_01047 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
PPPBDBBI_01048 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PPPBDBBI_01049 6.3e-235 sufD O assembly protein SufD
PPPBDBBI_01050 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PPPBDBBI_01051 3.8e-186 tagO 2.7.8.33, 2.7.8.35 M transferase
PPPBDBBI_01052 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PPPBDBBI_01053 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PPPBDBBI_01054 1.8e-276 glnP P ABC transporter
PPPBDBBI_01055 1e-123 glnQ E abc transporter atp-binding protein
PPPBDBBI_01058 5e-94 V VanZ like family
PPPBDBBI_01059 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PPPBDBBI_01060 6.5e-202 yhjX P Major Facilitator
PPPBDBBI_01061 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PPPBDBBI_01062 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PPPBDBBI_01063 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PPPBDBBI_01064 1.9e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PPPBDBBI_01065 5.6e-59 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PPPBDBBI_01066 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PPPBDBBI_01067 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PPPBDBBI_01068 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PPPBDBBI_01069 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PPPBDBBI_01070 2.4e-83 nrdI F Belongs to the NrdI family
PPPBDBBI_01071 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PPPBDBBI_01072 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PPPBDBBI_01073 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
PPPBDBBI_01074 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
PPPBDBBI_01075 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
PPPBDBBI_01076 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PPPBDBBI_01077 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PPPBDBBI_01078 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PPPBDBBI_01079 3.5e-149 ykuT M mechanosensitive ion channel
PPPBDBBI_01080 1.6e-77 sigH K DNA-templated transcription, initiation
PPPBDBBI_01081 3.6e-85
PPPBDBBI_01082 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PPPBDBBI_01083 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
PPPBDBBI_01084 9.9e-19 S Domain of unknown function (DUF4649)
PPPBDBBI_01087 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
PPPBDBBI_01088 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
PPPBDBBI_01089 6e-08 S Hydrolases of the alpha beta superfamily
PPPBDBBI_01090 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
PPPBDBBI_01091 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PPPBDBBI_01092 1.8e-159 czcD P cation diffusion facilitator family transporter
PPPBDBBI_01093 9e-98 K Transcriptional regulator, TetR family
PPPBDBBI_01094 1.6e-10
PPPBDBBI_01095 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPPBDBBI_01096 6.4e-104 V ABC transporter (Permease
PPPBDBBI_01097 2.1e-82 S reductase
PPPBDBBI_01098 2.6e-55 badR K DNA-binding transcription factor activity
PPPBDBBI_01099 5.5e-36 XK27_02060 S Transglycosylase associated protein
PPPBDBBI_01100 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PPPBDBBI_01101 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PPPBDBBI_01105 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
PPPBDBBI_01106 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
PPPBDBBI_01107 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PPPBDBBI_01108 1.1e-121 ylfI S tigr01906
PPPBDBBI_01109 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PPPBDBBI_01110 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PPPBDBBI_01111 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PPPBDBBI_01112 1.3e-22 XK27_08085
PPPBDBBI_01113 4.6e-132 2.1.1.223 S Putative SAM-dependent methyltransferase
PPPBDBBI_01114 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PPPBDBBI_01115 6.2e-38 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PPPBDBBI_01116 1.5e-18 V permease protein
PPPBDBBI_01117 3.6e-32 V efflux transmembrane transporter activity
PPPBDBBI_01118 7e-27 ytrF V efflux transmembrane transporter activity
PPPBDBBI_01119 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PPPBDBBI_01120 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PPPBDBBI_01121 7.5e-189 L Transposase
PPPBDBBI_01122 1.6e-18 L Integrase core domain
PPPBDBBI_01123 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
PPPBDBBI_01124 1.9e-21 L Helix-turn-helix domain
PPPBDBBI_01125 1.1e-82 L Helix-turn-helix domain
PPPBDBBI_01126 5.2e-164 L Integrase core domain protein
PPPBDBBI_01127 8.8e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PPPBDBBI_01128 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PPPBDBBI_01129 6.6e-61 EGP Major facilitator Superfamily
PPPBDBBI_01130 4.4e-135 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
PPPBDBBI_01131 1.1e-212 pqqE C radical SAM domain protein
PPPBDBBI_01133 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
PPPBDBBI_01134 9e-10
PPPBDBBI_01135 1.3e-66 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
PPPBDBBI_01136 0.0 L helicase
PPPBDBBI_01137 2.9e-190 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PPPBDBBI_01138 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PPPBDBBI_01139 2.7e-219 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PPPBDBBI_01140 1.5e-59 cysE 2.3.1.30 E serine acetyltransferase
PPPBDBBI_01141 1.9e-49 M YSIRK type signal peptide
PPPBDBBI_01142 3.4e-91 S MucBP domain
PPPBDBBI_01145 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PPPBDBBI_01146 3.5e-143 pts33BCA G pts system
PPPBDBBI_01147 5.8e-71 pts33BCA G pts system
PPPBDBBI_01148 4.8e-24 2.7.1.208, 2.7.1.211 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
PPPBDBBI_01149 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
PPPBDBBI_01150 1.8e-254 cycA E permease
PPPBDBBI_01151 4.5e-39 ynzC S UPF0291 protein
PPPBDBBI_01152 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PPPBDBBI_01153 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PPPBDBBI_01154 6.1e-63 S membrane
PPPBDBBI_01155 3.9e-60
PPPBDBBI_01156 2.2e-25
PPPBDBBI_01157 4.9e-51
PPPBDBBI_01158 8e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PPPBDBBI_01159 1.2e-92 nptA P COG1283 Na phosphate symporter
PPPBDBBI_01160 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
PPPBDBBI_01161 4.9e-106 mur1 NU mannosyl-glycoprotein
PPPBDBBI_01162 1.1e-53 glnB K Belongs to the P(II) protein family
PPPBDBBI_01163 7.5e-233 amt P Ammonium Transporter
PPPBDBBI_01164 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PPPBDBBI_01165 9.5e-55 yabA L Involved in initiation control of chromosome replication
PPPBDBBI_01166 1.2e-135 yaaT S stage 0 sporulation protein
PPPBDBBI_01167 4.2e-161 holB 2.7.7.7 L dna polymerase iii
PPPBDBBI_01168 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PPPBDBBI_01169 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PPPBDBBI_01170 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PPPBDBBI_01171 2.8e-230 ftsW D Belongs to the SEDS family
PPPBDBBI_01172 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PPPBDBBI_01173 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PPPBDBBI_01174 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PPPBDBBI_01175 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PPPBDBBI_01176 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PPPBDBBI_01177 3.3e-78 atpF C ATP synthase F(0) sector subunit b
PPPBDBBI_01178 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
PPPBDBBI_01179 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PPPBDBBI_01180 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PPPBDBBI_01181 1.9e-46 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PPPBDBBI_01182 5.6e-109 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PPPBDBBI_01183 1.5e-13 coiA 3.6.4.12 S Competence protein
PPPBDBBI_01184 2.2e-15 T peptidase
PPPBDBBI_01185 5.5e-153 rarD S Transporter
PPPBDBBI_01186 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PPPBDBBI_01187 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PPPBDBBI_01188 4.1e-132 yxkH G deacetylase
PPPBDBBI_01189 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PPPBDBBI_01190 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PPPBDBBI_01191 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PPPBDBBI_01192 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PPPBDBBI_01193 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PPPBDBBI_01194 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PPPBDBBI_01195 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
PPPBDBBI_01196 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
PPPBDBBI_01197 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PPPBDBBI_01198 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PPPBDBBI_01199 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PPPBDBBI_01200 8.6e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
PPPBDBBI_01201 7.1e-127 yrrM 2.1.1.104 S O-Methyltransferase
PPPBDBBI_01202 0.0 pepF E oligoendopeptidase F
PPPBDBBI_01203 3.2e-183 coiA 3.6.4.12 S Competence protein
PPPBDBBI_01204 1.8e-164 K transcriptional regulator (lysR family)
PPPBDBBI_01205 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PPPBDBBI_01209 8e-191 phoH T phosphate starvation-inducible protein PhoH
PPPBDBBI_01210 2.3e-61 rlpA M LysM domain protein
PPPBDBBI_01211 3e-121 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
PPPBDBBI_01212 1.6e-34 yozE S Belongs to the UPF0346 family
PPPBDBBI_01213 2e-160 cvfB S Protein conserved in bacteria
PPPBDBBI_01214 3.8e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PPPBDBBI_01215 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PPPBDBBI_01216 3.2e-78 sptS 2.7.13.3 T Histidine kinase
PPPBDBBI_01217 2.2e-18 K Acetyltransferase (GNAT) family
PPPBDBBI_01218 0.0 lmrA2 V abc transporter atp-binding protein
PPPBDBBI_01219 0.0 lmrA1 V abc transporter atp-binding protein
PPPBDBBI_01220 1.9e-77 K DNA-binding transcription factor activity
PPPBDBBI_01221 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PPPBDBBI_01222 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PPPBDBBI_01223 3.8e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
PPPBDBBI_01224 5.9e-140 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
PPPBDBBI_01225 1.6e-24 U response to pH
PPPBDBBI_01226 0.0 yfmR S abc transporter atp-binding protein
PPPBDBBI_01227 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PPPBDBBI_01228 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PPPBDBBI_01229 9.8e-91 XK27_08360 S EDD domain protein, DegV family
PPPBDBBI_01230 2.6e-64 WQ51_03320 S cog cog4835
PPPBDBBI_01231 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PPPBDBBI_01232 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PPPBDBBI_01233 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PPPBDBBI_01234 6.4e-29 2.3.1.128 K acetyltransferase
PPPBDBBI_01235 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PPPBDBBI_01236 1.1e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PPPBDBBI_01237 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PPPBDBBI_01238 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PPPBDBBI_01240 3.7e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PPPBDBBI_01241 7.9e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PPPBDBBI_01242 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
PPPBDBBI_01243 2.7e-126 fruA 2.7.1.202 G phosphotransferase system
PPPBDBBI_01244 2.2e-49 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
PPPBDBBI_01245 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
PPPBDBBI_01246 5.5e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PPPBDBBI_01247 5.6e-114 fruR K transcriptional
PPPBDBBI_01248 1.8e-84 L Transposase
PPPBDBBI_01249 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
PPPBDBBI_01250 5.2e-65 tnp L Transposase
PPPBDBBI_01251 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PPPBDBBI_01252 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PPPBDBBI_01253 4.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PPPBDBBI_01254 4.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PPPBDBBI_01255 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PPPBDBBI_01256 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PPPBDBBI_01257 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PPPBDBBI_01258 1.6e-126 IQ reductase
PPPBDBBI_01259 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PPPBDBBI_01260 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
PPPBDBBI_01261 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PPPBDBBI_01262 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PPPBDBBI_01263 4e-72 marR K Transcriptional regulator, MarR family
PPPBDBBI_01264 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
PPPBDBBI_01265 1.9e-115 S Haloacid dehalogenase-like hydrolase
PPPBDBBI_01266 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
PPPBDBBI_01267 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
PPPBDBBI_01268 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PPPBDBBI_01269 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
PPPBDBBI_01270 1.3e-101 ygaC J Belongs to the UPF0374 family
PPPBDBBI_01271 6.4e-108 S Domain of unknown function (DUF1803)
PPPBDBBI_01272 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
PPPBDBBI_01273 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
PPPBDBBI_01274 8.9e-206 potD P spermidine putrescine ABC transporter
PPPBDBBI_01275 3.1e-268 clcA P Chloride transporter, ClC family
PPPBDBBI_01277 5.9e-110 cpsD D COG0489 ATPases involved in chromosome partitioning
PPPBDBBI_01278 1.1e-105 cps4C M biosynthesis protein
PPPBDBBI_01279 1.5e-135 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
PPPBDBBI_01280 8e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
PPPBDBBI_01281 1e-13 rpmH J Ribosomal protein L34
PPPBDBBI_01282 1e-33 L Transposase
PPPBDBBI_01283 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PPPBDBBI_01287 1.3e-140 mreC M Involved in formation and maintenance of cell shape
PPPBDBBI_01288 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PPPBDBBI_01289 0.0 copB 3.6.3.4 P P-type ATPase
PPPBDBBI_01290 3.2e-42 L Transposase
PPPBDBBI_01291 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PPPBDBBI_01292 1.9e-87 bioY S biotin synthase
PPPBDBBI_01294 1.1e-33 XK27_12190 S protein conserved in bacteria
PPPBDBBI_01295 1.5e-48 hrtB V ABC transporter (Permease
PPPBDBBI_01296 1.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
PPPBDBBI_01297 9.2e-89 L Transposase
PPPBDBBI_01298 5.7e-95
PPPBDBBI_01299 2.4e-50 J Acetyltransferase (GNAT) domain
PPPBDBBI_01300 5.2e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PPPBDBBI_01301 4.5e-97 mip S hydroperoxide reductase activity
PPPBDBBI_01302 7e-203 I acyl-CoA dehydrogenase
PPPBDBBI_01303 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
PPPBDBBI_01304 1.4e-238 msrR K Transcriptional regulator
PPPBDBBI_01305 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
PPPBDBBI_01306 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PPPBDBBI_01307 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PPPBDBBI_01308 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PPPBDBBI_01309 3.2e-53 yheA S Belongs to the UPF0342 family
PPPBDBBI_01310 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PPPBDBBI_01311 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PPPBDBBI_01312 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PPPBDBBI_01313 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PPPBDBBI_01314 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PPPBDBBI_01315 2e-219 ywbD 2.1.1.191 J Methyltransferase
PPPBDBBI_01316 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PPPBDBBI_01317 2e-25 WQ51_00785
PPPBDBBI_01318 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PPPBDBBI_01319 1e-78 yueI S Protein of unknown function (DUF1694)
PPPBDBBI_01320 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PPPBDBBI_01321 6.6e-101 yyaQ V Protein conserved in bacteria
PPPBDBBI_01322 2.8e-28 yyaQ S YjbR
PPPBDBBI_01323 4.4e-183 ccpA K Catabolite control protein A
PPPBDBBI_01324 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
PPPBDBBI_01325 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
PPPBDBBI_01326 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PPPBDBBI_01327 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PPPBDBBI_01328 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PPPBDBBI_01329 2.6e-33 secG U Preprotein translocase subunit SecG
PPPBDBBI_01330 9.5e-74 mdtG EGP Major facilitator Superfamily
PPPBDBBI_01331 6e-133 mdtG EGP Major facilitator Superfamily
PPPBDBBI_01332 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PPPBDBBI_01333 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PPPBDBBI_01334 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PPPBDBBI_01335 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PPPBDBBI_01336 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PPPBDBBI_01337 6.8e-53 licT K transcriptional antiterminator
PPPBDBBI_01338 5.5e-62 licT K transcriptional antiterminator
PPPBDBBI_01339 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PPPBDBBI_01340 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
PPPBDBBI_01341 1.6e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PPPBDBBI_01342 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PPPBDBBI_01343 7.5e-23 I Alpha/beta hydrolase family
PPPBDBBI_01344 1.5e-35 yugF I carboxylic ester hydrolase activity
PPPBDBBI_01345 2.2e-45 K sequence-specific DNA binding
PPPBDBBI_01346 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PPPBDBBI_01347 1.5e-07
PPPBDBBI_01348 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PPPBDBBI_01349 5.3e-78 feoA P FeoA domain protein
PPPBDBBI_01350 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPBDBBI_01351 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
PPPBDBBI_01352 1.3e-34 ykuJ S protein conserved in bacteria
PPPBDBBI_01353 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PPPBDBBI_01354 0.0 clpE O Belongs to the ClpA ClpB family
PPPBDBBI_01355 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PPPBDBBI_01356 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
PPPBDBBI_01357 9.7e-66 S oxidoreductase
PPPBDBBI_01358 9.3e-59 S oxidoreductase
PPPBDBBI_01359 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
PPPBDBBI_01360 6.1e-70 M Pfam SNARE associated Golgi protein
PPPBDBBI_01361 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
PPPBDBBI_01364 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
PPPBDBBI_01367 4.8e-16 S Protein of unknown function (DUF2969)
PPPBDBBI_01368 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
PPPBDBBI_01369 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PPPBDBBI_01370 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PPPBDBBI_01371 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PPPBDBBI_01372 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
PPPBDBBI_01373 1.4e-29 S Domain of unknown function (DUF1912)
PPPBDBBI_01374 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
PPPBDBBI_01375 1.3e-249 mmuP E amino acid
PPPBDBBI_01376 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PPPBDBBI_01377 5.7e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PPPBDBBI_01378 9.7e-22
PPPBDBBI_01379 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PPPBDBBI_01380 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PPPBDBBI_01381 1.7e-218 mvaS 2.3.3.10 I synthase
PPPBDBBI_01382 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PPPBDBBI_01383 1e-25 K hmm pf08876
PPPBDBBI_01384 1.5e-118 yqfA K protein, Hemolysin III
PPPBDBBI_01385 1.2e-22 S Protein of unknown function (DUF3114)
PPPBDBBI_01386 9.8e-163 S Protein of unknown function (DUF3114)
PPPBDBBI_01387 9.9e-169 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PPPBDBBI_01388 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PPPBDBBI_01389 4.9e-21 XK27_13030
PPPBDBBI_01390 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PPPBDBBI_01391 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
PPPBDBBI_01392 1.1e-11 U protein secretion
PPPBDBBI_01393 2.1e-50 U protein secretion
PPPBDBBI_01394 3.5e-07 U protein secretion
PPPBDBBI_01396 5.9e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PPPBDBBI_01397 2.5e-21
PPPBDBBI_01398 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
PPPBDBBI_01399 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PPPBDBBI_01400 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PPPBDBBI_01401 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
PPPBDBBI_01402 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PPPBDBBI_01403 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PPPBDBBI_01404 4.6e-105 GBS0088 J protein conserved in bacteria
PPPBDBBI_01405 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PPPBDBBI_01406 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PPPBDBBI_01407 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
PPPBDBBI_01408 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PPPBDBBI_01409 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPPBDBBI_01410 2.5e-113 S VIT family
PPPBDBBI_01411 1.7e-142 deoD_1 2.4.2.3 F Phosphorylase superfamily
PPPBDBBI_01412 4.3e-22
PPPBDBBI_01413 1.2e-26 XK27_00085 K Transcriptional
PPPBDBBI_01414 1e-195 yceA S Belongs to the UPF0176 family
PPPBDBBI_01415 5.4e-122 sagI S ABC-2 type transporter
PPPBDBBI_01416 4.8e-168 V ABC transporter
PPPBDBBI_01417 1.1e-217 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PPPBDBBI_01418 2.5e-132 rr02 KT response regulator
PPPBDBBI_01419 1.3e-214 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PPPBDBBI_01420 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PPPBDBBI_01421 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PPPBDBBI_01422 0.0 lmrA V abc transporter atp-binding protein
PPPBDBBI_01423 0.0 mdlB V abc transporter atp-binding protein
PPPBDBBI_01425 3.6e-68 M the current gene model (or a revised gene model) may contain a
PPPBDBBI_01428 5.3e-11
PPPBDBBI_01431 8.2e-232 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PPPBDBBI_01432 2.7e-23 rgpAc GT4 M group 1 family protein
PPPBDBBI_01433 2.7e-73 L Transposase DDE domain
PPPBDBBI_01434 5.6e-62 L Transposase DDE domain
PPPBDBBI_01435 1.2e-71 cps1D M Domain of unknown function (DUF4422)
PPPBDBBI_01436 7.7e-100
PPPBDBBI_01437 4.8e-102 M group 2 family protein
PPPBDBBI_01438 1.8e-32 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PPPBDBBI_01439 8.7e-88 2.7.8.12 GT2 M Glycosyltransferase like family 2
PPPBDBBI_01440 1.8e-238 cps1C S Polysaccharide biosynthesis protein
PPPBDBBI_01441 1.4e-172 epsU S Polysaccharide biosynthesis protein
PPPBDBBI_01442 6e-20 epsU S Polysaccharide biosynthesis protein
PPPBDBBI_01443 8.2e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
PPPBDBBI_01444 4.3e-236 L Transposase
PPPBDBBI_01445 5.8e-95 V VanZ like family
PPPBDBBI_01446 9.2e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PPPBDBBI_01447 8.4e-69 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
PPPBDBBI_01448 9.5e-89 G Belongs to the phosphoglycerate mutase family
PPPBDBBI_01449 1.3e-199 S hmm pf01594
PPPBDBBI_01450 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPPBDBBI_01451 2.1e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPPBDBBI_01452 4.9e-39 S granule-associated protein
PPPBDBBI_01453 1.8e-292 S unusual protein kinase
PPPBDBBI_01454 3.4e-29 estA E Lysophospholipase L1 and related esterases
PPPBDBBI_01455 1.8e-69 estA E GDSL-like protein
PPPBDBBI_01456 1.2e-157 rssA S Phospholipase, patatin family
PPPBDBBI_01457 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
PPPBDBBI_01458 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
PPPBDBBI_01459 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
PPPBDBBI_01460 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PPPBDBBI_01461 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PPPBDBBI_01462 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PPPBDBBI_01463 2.4e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PPPBDBBI_01464 0.0 S the current gene model (or a revised gene model) may contain a frame shift
PPPBDBBI_01465 0.0 cas3 L CRISPR-associated helicase cas3
PPPBDBBI_01466 0.0 casA L the current gene model (or a revised gene model) may contain a frame shift
PPPBDBBI_01467 6e-103 casB S CRISPR system CASCADE complex protein CasB
PPPBDBBI_01468 5.8e-181 casC L CT1975-like protein
PPPBDBBI_01469 3.6e-134 casD S CRISPR system CASCADE complex protein CasD
PPPBDBBI_01470 3.2e-110 casE S CRISPR system CASCADE complex protein CasE
PPPBDBBI_01471 5.8e-169 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPBDBBI_01472 1.3e-160 cas2 2.7.7.7 L CRISPR-associated endoribonuclease Cas2
PPPBDBBI_01473 1.6e-52 2.7.13.3 T protein histidine kinase activity
PPPBDBBI_01474 3.6e-37 2.7.13.3 T protein histidine kinase activity
PPPBDBBI_01475 2.2e-83 2.7.13.3 T protein histidine kinase activity
PPPBDBBI_01476 3.1e-45 hpk9 2.7.13.3 T protein histidine kinase activity
PPPBDBBI_01477 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PPPBDBBI_01478 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PPPBDBBI_01479 5.4e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PPPBDBBI_01480 0.0 lpdA 1.8.1.4 C Dehydrogenase
PPPBDBBI_01481 6.4e-11 3.5.1.28 NU amidase activity
PPPBDBBI_01482 7.9e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PPPBDBBI_01483 2.2e-112 3.5.1.28 M GBS Bsp-like repeat
PPPBDBBI_01484 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPBDBBI_01485 6.1e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPBDBBI_01486 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPBDBBI_01487 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPBDBBI_01488 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PPPBDBBI_01489 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPPBDBBI_01490 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPPBDBBI_01491 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
PPPBDBBI_01492 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
PPPBDBBI_01493 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
PPPBDBBI_01494 5.6e-233 ycdB P peroxidase
PPPBDBBI_01495 8.8e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
PPPBDBBI_01496 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PPPBDBBI_01497 4.6e-25 tatA U protein secretion
PPPBDBBI_01498 1e-23 L Transposase
PPPBDBBI_01499 2.3e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
PPPBDBBI_01500 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PPPBDBBI_01501 3.7e-09
PPPBDBBI_01502 1.1e-17
PPPBDBBI_01503 7.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
PPPBDBBI_01504 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PPPBDBBI_01505 0.0 pepN 3.4.11.2 E aminopeptidase
PPPBDBBI_01506 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
PPPBDBBI_01507 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PPPBDBBI_01508 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PPPBDBBI_01509 1.2e-155 pstA P phosphate transport system permease
PPPBDBBI_01510 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
PPPBDBBI_01511 3.3e-158 pstS P phosphate
PPPBDBBI_01512 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PPPBDBBI_01513 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PPPBDBBI_01514 1.9e-43 yktA S Belongs to the UPF0223 family
PPPBDBBI_01515 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PPPBDBBI_01516 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PPPBDBBI_01517 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PPPBDBBI_01518 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
PPPBDBBI_01519 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
PPPBDBBI_01520 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
PPPBDBBI_01521 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PPPBDBBI_01522 9.3e-62 S haloacid dehalogenase-like hydrolase
PPPBDBBI_01523 1.8e-59 Q phosphatase activity
PPPBDBBI_01524 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
PPPBDBBI_01525 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PPPBDBBI_01526 1.8e-240 agcS E (Alanine) symporter
PPPBDBBI_01527 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PPPBDBBI_01528 1.4e-104 yfiF3 K sequence-specific DNA binding
PPPBDBBI_01529 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
PPPBDBBI_01530 2e-272 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
PPPBDBBI_01532 2.3e-20 yecS P amino acid transport
PPPBDBBI_01533 2.3e-62 yecS P ABC transporter (Permease
PPPBDBBI_01534 1.6e-266 dtpT E transporter
PPPBDBBI_01536 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PPPBDBBI_01537 8e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PPPBDBBI_01538 9.5e-32 csm6 S Psort location Cytoplasmic, score
PPPBDBBI_01540 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
PPPBDBBI_01541 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
PPPBDBBI_01542 1.6e-117 csm3 L RAMP superfamily
PPPBDBBI_01543 2.5e-62 csm2 L Csm2 Type III-A
PPPBDBBI_01544 0.0 csm1 S CRISPR-associated protein Csm1 family
PPPBDBBI_01545 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
PPPBDBBI_01546 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPBDBBI_01547 2.8e-185 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PPPBDBBI_01548 3.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PPPBDBBI_01549 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PPPBDBBI_01550 1.7e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
PPPBDBBI_01551 1.8e-88 S TraX protein
PPPBDBBI_01552 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PPPBDBBI_01554 6.3e-12 dinF V Mate efflux family protein
PPPBDBBI_01555 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
PPPBDBBI_01556 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
PPPBDBBI_01557 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
PPPBDBBI_01558 6.7e-43 2.4.2.3 F Phosphorylase superfamily
PPPBDBBI_01559 1.3e-87 S Fusaric acid resistance protein-like
PPPBDBBI_01560 8.5e-63 glnR K Transcriptional regulator
PPPBDBBI_01561 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
PPPBDBBI_01562 2.7e-40 pscB M CHAP domain protein
PPPBDBBI_01563 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PPPBDBBI_01564 2.5e-33 ykzG S Belongs to the UPF0356 family
PPPBDBBI_01565 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
PPPBDBBI_01566 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PPPBDBBI_01567 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PPPBDBBI_01568 1.8e-114 azlC E AzlC protein
PPPBDBBI_01569 2e-47 azlD E branched-chain amino acid
PPPBDBBI_01570 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PPPBDBBI_01571 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PPPBDBBI_01572 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PPPBDBBI_01573 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PPPBDBBI_01574 1e-93 cvpA S toxin biosynthetic process
PPPBDBBI_01575 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PPPBDBBI_01576 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PPPBDBBI_01581 2.5e-230 mutY L A G-specific adenine glycosylase
PPPBDBBI_01582 3.6e-41 XK27_05745
PPPBDBBI_01583 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PPPBDBBI_01584 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PPPBDBBI_01585 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PPPBDBBI_01587 3.1e-124 XK27_01040 S Pfam PF06570
PPPBDBBI_01588 2e-169 corA P COG0598 Mg2 and Co2 transporters
PPPBDBBI_01589 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PPPBDBBI_01592 3.8e-58 V 'abc transporter, ATP-binding protein
PPPBDBBI_01593 8e-44 V 'abc transporter, ATP-binding protein
PPPBDBBI_01595 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
PPPBDBBI_01596 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
PPPBDBBI_01597 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PPPBDBBI_01598 3.4e-62 yqhY S protein conserved in bacteria
PPPBDBBI_01599 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PPPBDBBI_01600 2.2e-179 scrR K Transcriptional
PPPBDBBI_01601 4.1e-291 scrB 3.2.1.26 GH32 G invertase
PPPBDBBI_01602 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
PPPBDBBI_01603 1.2e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
PPPBDBBI_01604 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
PPPBDBBI_01606 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PPPBDBBI_01607 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PPPBDBBI_01608 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PPPBDBBI_01609 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PPPBDBBI_01610 7.5e-184 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PPPBDBBI_01611 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PPPBDBBI_01613 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PPPBDBBI_01614 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
PPPBDBBI_01615 2.9e-18 yebC M Membrane
PPPBDBBI_01616 5.2e-81 yebC M Membrane
PPPBDBBI_01617 3.6e-66 KT response to antibiotic
PPPBDBBI_01618 5.2e-75 XK27_02470 K LytTr DNA-binding domain
PPPBDBBI_01619 2.6e-121 liaI S membrane
PPPBDBBI_01620 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PPPBDBBI_01621 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PPPBDBBI_01622 5.2e-125 S Protein of unknown function (DUF554)
PPPBDBBI_01623 8.1e-134 ecsA_2 V abc transporter atp-binding protein
PPPBDBBI_01624 2.2e-285 XK27_00765
PPPBDBBI_01625 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PPPBDBBI_01626 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PPPBDBBI_01627 4.5e-18 D nuclear chromosome segregation
PPPBDBBI_01628 8.7e-33 yhaI J Protein of unknown function (DUF805)
PPPBDBBI_01630 2.6e-30
PPPBDBBI_01631 7.4e-27
PPPBDBBI_01632 1.6e-65
PPPBDBBI_01633 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PPPBDBBI_01634 4.3e-47 ftsL D cell division protein FtsL
PPPBDBBI_01635 0.0 ftsI 3.4.16.4 M penicillin-binding protein
PPPBDBBI_01636 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PPPBDBBI_01637 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PPPBDBBI_01639 4.3e-269 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PPPBDBBI_01640 2.3e-72 yutD J protein conserved in bacteria
PPPBDBBI_01641 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PPPBDBBI_01642 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
PPPBDBBI_01644 0.0 mdlA V abc transporter atp-binding protein
PPPBDBBI_01645 0.0 mdlB V abc transporter atp-binding protein
PPPBDBBI_01646 2.8e-108 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PPPBDBBI_01647 9.3e-281 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PPPBDBBI_01648 7.3e-237 mesE M Transport protein ComB
PPPBDBBI_01650 2.5e-234 blpH 2.7.13.3 T protein histidine kinase activity
PPPBDBBI_01651 8.9e-133 agrA KT phosphorelay signal transduction system
PPPBDBBI_01654 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
PPPBDBBI_01659 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PPPBDBBI_01660 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPPBDBBI_01661 3.9e-237 dltB M Membrane protein involved in D-alanine export
PPPBDBBI_01662 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPPBDBBI_01663 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
PPPBDBBI_01664 0.0 XK27_10035 V abc transporter atp-binding protein
PPPBDBBI_01665 0.0 yfiB1 V abc transporter atp-binding protein
PPPBDBBI_01666 6.6e-105 pvaA M lytic transglycosylase activity
PPPBDBBI_01667 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
PPPBDBBI_01668 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PPPBDBBI_01669 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PPPBDBBI_01670 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PPPBDBBI_01671 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PPPBDBBI_01672 2.4e-112 tdk 2.7.1.21 F thymidine kinase
PPPBDBBI_01673 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PPPBDBBI_01674 3.1e-155 gst O Glutathione S-transferase
PPPBDBBI_01675 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
PPPBDBBI_01676 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PPPBDBBI_01677 2e-45 rpmE2 J 50S ribosomal protein L31
PPPBDBBI_01678 3.6e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
PPPBDBBI_01679 2e-11
PPPBDBBI_01680 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PPPBDBBI_01681 1.8e-135 divIVA D Cell division protein DivIVA
PPPBDBBI_01682 1.2e-143 ylmH T S4 RNA-binding domain
PPPBDBBI_01683 2.6e-34 yggT D integral membrane protein
PPPBDBBI_01684 6.8e-96 sepF D cell septum assembly
PPPBDBBI_01685 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PPPBDBBI_01686 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PPPBDBBI_01687 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PPPBDBBI_01688 9.7e-171 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PPPBDBBI_01689 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PPPBDBBI_01690 4.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PPPBDBBI_01692 0.0 typA T GTP-binding protein TypA
PPPBDBBI_01693 2.2e-179 glk 2.7.1.2 G Glucokinase
PPPBDBBI_01694 8.4e-28 yqgQ S protein conserved in bacteria
PPPBDBBI_01695 1.1e-80 perR P Belongs to the Fur family
PPPBDBBI_01696 3.5e-91 dps P Belongs to the Dps family
PPPBDBBI_01697 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PPPBDBBI_01698 2e-186 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
PPPBDBBI_01699 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
PPPBDBBI_01700 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
PPPBDBBI_01701 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PPPBDBBI_01702 6.2e-56 S Domain of unknown function (DUF4430)
PPPBDBBI_01703 1.8e-73 S Psort location CytoplasmicMembrane, score
PPPBDBBI_01704 6.4e-133 htpX O Belongs to the peptidase M48B family
PPPBDBBI_01705 9e-93 lemA S LemA family
PPPBDBBI_01706 9.9e-90 spd F DNA RNA non-specific endonuclease
PPPBDBBI_01707 4.8e-61 spd F DNA RNA non-specific endonuclease
PPPBDBBI_01709 9.6e-305 hsdM 2.1.1.72 V type I restriction-modification system
PPPBDBBI_01710 3e-131 S Protein conserved in bacteria
PPPBDBBI_01711 0.0 S KAP family P-loop domain
PPPBDBBI_01712 2.8e-131 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PPPBDBBI_01713 5.3e-08
PPPBDBBI_01715 1.4e-68
PPPBDBBI_01716 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PPPBDBBI_01717 2.5e-103 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PPPBDBBI_01719 4.7e-23 MA20_36090 S Protein of unknown function (DUF2974)
PPPBDBBI_01720 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
PPPBDBBI_01721 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PPPBDBBI_01722 2.7e-27 P Hemerythrin HHE cation binding domain protein
PPPBDBBI_01723 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
PPPBDBBI_01724 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PPPBDBBI_01725 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
PPPBDBBI_01726 1.5e-174 S hydrolase
PPPBDBBI_01727 7.6e-16
PPPBDBBI_01728 1e-163 M LysM domain
PPPBDBBI_01729 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PPPBDBBI_01731 3.3e-95 ywlG S Belongs to the UPF0340 family
PPPBDBBI_01732 1.2e-85 treR K trehalose operon
PPPBDBBI_01733 5.8e-21 treR K DNA-binding transcription factor activity
PPPBDBBI_01734 1.4e-54 treB 2.7.1.201 G PTS System
PPPBDBBI_01735 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PPPBDBBI_01736 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PPPBDBBI_01737 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PPPBDBBI_01738 0.0 pepO 3.4.24.71 O Peptidase family M13
PPPBDBBI_01739 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
PPPBDBBI_01740 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PPPBDBBI_01741 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PPPBDBBI_01742 1.2e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
PPPBDBBI_01743 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PPPBDBBI_01744 1.9e-278 thrC 4.2.3.1 E Threonine synthase
PPPBDBBI_01745 3.2e-226 norN V Mate efflux family protein
PPPBDBBI_01746 1.8e-57 asp S cog cog1302
PPPBDBBI_01747 9.9e-305 yloV S kinase related to dihydroxyacetone kinase
PPPBDBBI_01748 8.4e-09 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PPPBDBBI_01749 1.5e-280 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PPPBDBBI_01750 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
PPPBDBBI_01751 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
PPPBDBBI_01752 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PPPBDBBI_01753 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PPPBDBBI_01754 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PPPBDBBI_01755 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPPBDBBI_01756 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPPBDBBI_01757 2.9e-68 S cog cog4699
PPPBDBBI_01758 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PPPBDBBI_01759 1.1e-156 cglB U protein transport across the cell outer membrane
PPPBDBBI_01760 8.5e-43 comGC U Required for transformation and DNA binding
PPPBDBBI_01761 1.8e-57 cglD NU Competence protein
PPPBDBBI_01762 1.1e-15 NU Type II secretory pathway pseudopilin
PPPBDBBI_01763 1.5e-71 comGF U Competence protein ComGF
PPPBDBBI_01764 2e-12 comGF U Putative Competence protein ComGF
PPPBDBBI_01765 5.9e-177 ytxK 2.1.1.72 L DNA methylase
PPPBDBBI_01766 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PPPBDBBI_01768 1.4e-33 V CAAX protease self-immunity
PPPBDBBI_01769 5e-67 V CAAX protease self-immunity
PPPBDBBI_01771 1.8e-111 S CAAX amino terminal protease family protein
PPPBDBBI_01772 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PPPBDBBI_01773 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PPPBDBBI_01774 4.1e-09 S Domain of unknown function (DUF4651)
PPPBDBBI_01775 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PPPBDBBI_01776 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PPPBDBBI_01777 1e-190 yeeE S Sulphur transport
PPPBDBBI_01778 6.4e-37 yeeD O sulfur carrier activity
PPPBDBBI_01779 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PPPBDBBI_01780 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PPPBDBBI_01782 7e-158 rrmA 2.1.1.187 Q methyltransferase
PPPBDBBI_01783 1.3e-63 S phosphatase activity
PPPBDBBI_01784 2.7e-48 S glycolate biosynthetic process
PPPBDBBI_01785 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PPPBDBBI_01786 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PPPBDBBI_01787 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PPPBDBBI_01788 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PPPBDBBI_01789 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PPPBDBBI_01790 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PPPBDBBI_01791 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
PPPBDBBI_01792 3.2e-62 fnt P Formate nitrite transporter
PPPBDBBI_01793 2.3e-141 XK27_09615 C reductase
PPPBDBBI_01794 9e-62 XK27_09615 C reductase
PPPBDBBI_01795 4.3e-77 XK27_09620 S reductase
PPPBDBBI_01796 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
PPPBDBBI_01797 5.4e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PPPBDBBI_01798 1.7e-221 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PPPBDBBI_01799 1.8e-11 WQ51_05710 S Mitochondrial biogenesis AIM24
PPPBDBBI_01800 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
PPPBDBBI_01801 6.6e-87 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PPPBDBBI_01802 9.2e-51 S Protein of unknown function (DUF3397)
PPPBDBBI_01803 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PPPBDBBI_01804 1.8e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PPPBDBBI_01805 4.2e-74 amiA E transmembrane transport
PPPBDBBI_01806 2.8e-79 amiA E transmembrane transport
PPPBDBBI_01807 6e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PPPBDBBI_01808 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PPPBDBBI_01809 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
PPPBDBBI_01810 7.6e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PPPBDBBI_01811 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PPPBDBBI_01812 2e-186 jag S RNA-binding protein
PPPBDBBI_01814 3.2e-09 Q the current gene model (or a revised gene model) may contain a frame shift
PPPBDBBI_01815 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
PPPBDBBI_01816 6.9e-41 Q the current gene model (or a revised gene model) may contain a frame shift
PPPBDBBI_01818 1.6e-16 S Domain of unknown function (DUF4649)
PPPBDBBI_01819 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
PPPBDBBI_01820 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
PPPBDBBI_01821 1.2e-135 XK27_08845 S abc transporter atp-binding protein
PPPBDBBI_01822 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PPPBDBBI_01823 3.5e-151 estA CE1 S Putative esterase
PPPBDBBI_01824 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
PPPBDBBI_01826 2.3e-75 fld C Flavodoxin
PPPBDBBI_01827 6.4e-282 clcA P Chloride transporter, ClC family
PPPBDBBI_01828 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
PPPBDBBI_01829 2.1e-219 XK27_05110 P chloride
PPPBDBBI_01830 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PPPBDBBI_01833 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
PPPBDBBI_01834 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PPPBDBBI_01835 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
PPPBDBBI_01836 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PPPBDBBI_01837 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PPPBDBBI_01838 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PPPBDBBI_01839 8.3e-28 G Domain of unknown function (DUF4832)
PPPBDBBI_01840 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPPBDBBI_01842 1.1e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PPPBDBBI_01843 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
PPPBDBBI_01844 2.4e-124 endA F DNA RNA non-specific endonuclease
PPPBDBBI_01845 5e-111 tcyB_2 P ABC transporter (permease)
PPPBDBBI_01846 5.9e-118 gltJ P ABC transporter (Permease
PPPBDBBI_01847 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PPPBDBBI_01848 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
PPPBDBBI_01849 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPPBDBBI_01850 1.5e-247 vicK 2.7.13.3 T Histidine kinase
PPPBDBBI_01851 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
PPPBDBBI_01852 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
PPPBDBBI_01853 9.2e-147 yidA S hydrolases of the HAD superfamily
PPPBDBBI_01854 3.6e-45 XK27_00115 2.3.1.128 K acetyltransferase
PPPBDBBI_01855 2.6e-67 ywiB S Domain of unknown function (DUF1934)
PPPBDBBI_01856 0.0 pacL 3.6.3.8 P cation transport ATPase
PPPBDBBI_01857 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PPPBDBBI_01858 4.3e-180 yjjH S Calcineurin-like phosphoesterase
PPPBDBBI_01859 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PPPBDBBI_01860 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PPPBDBBI_01861 2.5e-124 ftsE D cell division ATP-binding protein FtsE
PPPBDBBI_01862 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PPPBDBBI_01863 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
PPPBDBBI_01864 6.2e-176 yubA S permease
PPPBDBBI_01865 3.7e-224 G COG0457 FOG TPR repeat
PPPBDBBI_01866 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PPPBDBBI_01867 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PPPBDBBI_01868 2.9e-90 ebsA S Family of unknown function (DUF5322)
PPPBDBBI_01869 3.9e-15 M LysM domain
PPPBDBBI_01870 6.6e-122 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PPPBDBBI_01871 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PPPBDBBI_01872 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PPPBDBBI_01873 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PPPBDBBI_01874 4.7e-24 L Transposase
PPPBDBBI_01875 6.9e-86 XK27_03610 K Gnat family
PPPBDBBI_01876 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PPPBDBBI_01877 8.2e-276 pepV 3.5.1.18 E Dipeptidase
PPPBDBBI_01878 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
PPPBDBBI_01879 6.1e-22 V Glucan-binding protein C
PPPBDBBI_01881 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PPPBDBBI_01882 8.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PPPBDBBI_01883 8.1e-41 S Protein of unknown function (DUF1697)
PPPBDBBI_01884 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PPPBDBBI_01885 4e-64 clcA_2 P chloride
PPPBDBBI_01886 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
PPPBDBBI_01887 7e-38 yfeJ 6.3.5.2 F glutamine amidotransferase
PPPBDBBI_01888 2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)