ORF_ID e_value Gene_name EC_number CAZy COGs Description
KCKOBFID_00001 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCKOBFID_00002 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KCKOBFID_00003 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
KCKOBFID_00004 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCKOBFID_00005 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCKOBFID_00006 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCKOBFID_00007 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCKOBFID_00008 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCKOBFID_00009 1e-68 S cog cog4699
KCKOBFID_00010 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCKOBFID_00011 1.1e-156 cglB U protein transport across the cell outer membrane
KCKOBFID_00012 8.5e-43 comGC U Required for transformation and DNA binding
KCKOBFID_00013 1.8e-57 cglD NU Competence protein
KCKOBFID_00014 1.4e-15 NU Type II secretory pathway pseudopilin
KCKOBFID_00015 1.5e-71 comGF U Competence protein ComGF
KCKOBFID_00016 2e-12 comGF U Putative Competence protein ComGF
KCKOBFID_00017 5.9e-177 ytxK 2.1.1.72 L DNA methylase
KCKOBFID_00018 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCKOBFID_00019 8.8e-27 lanR K sequence-specific DNA binding
KCKOBFID_00020 1.4e-33 V CAAX protease self-immunity
KCKOBFID_00021 5e-67 V CAAX protease self-immunity
KCKOBFID_00023 1.8e-111 S CAAX amino terminal protease family protein
KCKOBFID_00024 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCKOBFID_00025 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KCKOBFID_00026 4.1e-09 S Domain of unknown function (DUF4651)
KCKOBFID_00027 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KCKOBFID_00028 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCKOBFID_00029 2.8e-193 yeeE S Sulphur transport
KCKOBFID_00030 8.3e-37 yeeD O sulfur carrier activity
KCKOBFID_00031 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCKOBFID_00032 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KCKOBFID_00035 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
KCKOBFID_00036 1.5e-64 S phosphatase activity
KCKOBFID_00037 2.7e-48 S glycolate biosynthetic process
KCKOBFID_00038 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KCKOBFID_00039 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KCKOBFID_00040 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCKOBFID_00041 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KCKOBFID_00042 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KCKOBFID_00043 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KCKOBFID_00044 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
KCKOBFID_00045 3.2e-62 fnt P Formate nitrite transporter
KCKOBFID_00046 1e-141 XK27_09615 C reductase
KCKOBFID_00047 9e-62 XK27_09615 C reductase
KCKOBFID_00048 4.3e-77 XK27_09620 S reductase
KCKOBFID_00049 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
KCKOBFID_00050 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KCKOBFID_00051 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCKOBFID_00052 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
KCKOBFID_00053 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
KCKOBFID_00054 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
KCKOBFID_00055 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KCKOBFID_00056 9.2e-51 S Protein of unknown function (DUF3397)
KCKOBFID_00057 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCKOBFID_00058 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KCKOBFID_00059 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
KCKOBFID_00060 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
KCKOBFID_00061 2e-41 amiA E transmembrane transport
KCKOBFID_00062 6.7e-81 amiA E transmembrane transport
KCKOBFID_00063 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCKOBFID_00064 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KCKOBFID_00065 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
KCKOBFID_00066 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KCKOBFID_00067 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCKOBFID_00068 2e-186 jag S RNA-binding protein
KCKOBFID_00069 1e-13 rpmH J Ribosomal protein L34
KCKOBFID_00070 1e-33 L Transposase
KCKOBFID_00071 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KCKOBFID_00072 3.7e-151 K Helix-turn-helix XRE-family like proteins
KCKOBFID_00073 9.2e-284 V ABC transporter transmembrane region
KCKOBFID_00074 2.9e-31 yozG K Transcriptional regulator
KCKOBFID_00077 2.1e-185 V Abi-like protein
KCKOBFID_00079 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCKOBFID_00080 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCKOBFID_00081 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KCKOBFID_00082 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCKOBFID_00083 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCKOBFID_00084 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KCKOBFID_00086 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCKOBFID_00087 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KCKOBFID_00088 0.0 scrA 2.7.1.211 G pts system
KCKOBFID_00089 5.4e-291 scrB 3.2.1.26 GH32 G invertase
KCKOBFID_00090 7.5e-180 scrR K Transcriptional
KCKOBFID_00091 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCKOBFID_00092 3.4e-62 yqhY S protein conserved in bacteria
KCKOBFID_00093 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCKOBFID_00094 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
KCKOBFID_00095 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KCKOBFID_00097 8e-44 V 'abc transporter, ATP-binding protein
KCKOBFID_00098 3.8e-58 V 'abc transporter, ATP-binding protein
KCKOBFID_00101 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCKOBFID_00102 2e-169 corA P COG0598 Mg2 and Co2 transporters
KCKOBFID_00103 3.1e-124 XK27_01040 S Pfam PF06570
KCKOBFID_00105 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KCKOBFID_00106 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCKOBFID_00107 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KCKOBFID_00108 3.6e-41 XK27_05745
KCKOBFID_00109 2.5e-230 mutY L A G-specific adenine glycosylase
KCKOBFID_00115 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCKOBFID_00116 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KCKOBFID_00117 1e-93 cvpA S toxin biosynthetic process
KCKOBFID_00118 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KCKOBFID_00119 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCKOBFID_00120 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCKOBFID_00121 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KCKOBFID_00122 2e-47 azlD E branched-chain amino acid
KCKOBFID_00123 1.3e-117 azlC E AzlC protein
KCKOBFID_00124 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCKOBFID_00125 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KCKOBFID_00126 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KCKOBFID_00127 2.5e-33 ykzG S Belongs to the UPF0356 family
KCKOBFID_00128 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCKOBFID_00129 2.7e-40 pscB M CHAP domain protein
KCKOBFID_00130 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
KCKOBFID_00131 8.5e-63 glnR K Transcriptional regulator
KCKOBFID_00132 1.3e-87 S Fusaric acid resistance protein-like
KCKOBFID_00133 0.0 M the current gene model (or a revised gene model) may contain a
KCKOBFID_00135 0.0 mdlB V abc transporter atp-binding protein
KCKOBFID_00136 0.0 lmrA V abc transporter atp-binding protein
KCKOBFID_00137 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCKOBFID_00138 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KCKOBFID_00139 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KCKOBFID_00140 2.5e-132 rr02 KT response regulator
KCKOBFID_00141 7.1e-214 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KCKOBFID_00142 2.8e-168 V ABC transporter
KCKOBFID_00143 5.4e-122 sagI S ABC-2 type transporter
KCKOBFID_00144 2.4e-197 yceA S Belongs to the UPF0176 family
KCKOBFID_00145 8e-28 XK27_00085 K Transcriptional
KCKOBFID_00146 1.1e-22
KCKOBFID_00147 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
KCKOBFID_00148 8.7e-114 S VIT family
KCKOBFID_00149 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCKOBFID_00150 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KCKOBFID_00151 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
KCKOBFID_00152 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KCKOBFID_00153 6.1e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCKOBFID_00154 4.6e-105 GBS0088 J protein conserved in bacteria
KCKOBFID_00155 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KCKOBFID_00156 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KCKOBFID_00157 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
KCKOBFID_00158 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KCKOBFID_00159 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCKOBFID_00160 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KCKOBFID_00161 2.5e-21
KCKOBFID_00162 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCKOBFID_00164 3.5e-07 U protein secretion
KCKOBFID_00165 2.1e-50 U protein secretion
KCKOBFID_00167 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KCKOBFID_00168 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KCKOBFID_00169 4.9e-21 XK27_13030
KCKOBFID_00170 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCKOBFID_00171 8.9e-57 S hydrolase activity, acting on ester bonds
KCKOBFID_00172 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KCKOBFID_00173 8.6e-167 S Protein of unknown function (DUF3114)
KCKOBFID_00174 1.2e-22 S Protein of unknown function (DUF3114)
KCKOBFID_00175 1.5e-118 yqfA K protein, Hemolysin III
KCKOBFID_00176 1e-25 K hmm pf08876
KCKOBFID_00177 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KCKOBFID_00178 1.7e-218 mvaS 2.3.3.10 I synthase
KCKOBFID_00179 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KCKOBFID_00180 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCKOBFID_00181 9.7e-22
KCKOBFID_00182 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCKOBFID_00183 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
KCKOBFID_00184 5.2e-251 mmuP E amino acid
KCKOBFID_00185 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KCKOBFID_00186 1.4e-29 S Domain of unknown function (DUF1912)
KCKOBFID_00187 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
KCKOBFID_00188 0.0 yfmR S abc transporter atp-binding protein
KCKOBFID_00189 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KCKOBFID_00190 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KCKOBFID_00191 3.6e-74 XK27_08360 S EDD domain protein, DegV family
KCKOBFID_00192 6.4e-61 XK27_08360 S EDD domain protein, DegV family
KCKOBFID_00193 2.6e-64 WQ51_03320 S cog cog4835
KCKOBFID_00194 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCKOBFID_00195 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KCKOBFID_00196 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KCKOBFID_00197 6.4e-29 2.3.1.128 K acetyltransferase
KCKOBFID_00198 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KCKOBFID_00199 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KCKOBFID_00200 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCKOBFID_00201 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KCKOBFID_00203 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCKOBFID_00204 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCKOBFID_00205 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
KCKOBFID_00206 5.1e-145 fruA 2.7.1.202 G phosphotransferase system
KCKOBFID_00207 8e-98 fruA 2.7.1.202 G phosphotransferase system
KCKOBFID_00208 2.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KCKOBFID_00209 5.6e-114 fruR K transcriptional
KCKOBFID_00210 1.8e-84 L Transposase
KCKOBFID_00211 1.1e-202 rny D Endoribonuclease that initiates mRNA decay
KCKOBFID_00212 1.4e-65 tnp L Transposase
KCKOBFID_00213 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KCKOBFID_00214 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KCKOBFID_00215 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCKOBFID_00216 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KCKOBFID_00217 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KCKOBFID_00218 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KCKOBFID_00219 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KCKOBFID_00220 1.6e-126 IQ reductase
KCKOBFID_00221 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KCKOBFID_00222 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KCKOBFID_00223 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCKOBFID_00224 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCKOBFID_00225 4e-72 marR K Transcriptional regulator, MarR family
KCKOBFID_00226 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KCKOBFID_00227 1.9e-115 S Haloacid dehalogenase-like hydrolase
KCKOBFID_00228 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
KCKOBFID_00229 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
KCKOBFID_00230 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCKOBFID_00231 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
KCKOBFID_00232 1.3e-101 ygaC J Belongs to the UPF0374 family
KCKOBFID_00233 6.4e-108 S Domain of unknown function (DUF1803)
KCKOBFID_00234 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KCKOBFID_00241 3.7e-63
KCKOBFID_00242 1.8e-23 S Small integral membrane protein
KCKOBFID_00243 1.1e-71 M Protein conserved in bacteria
KCKOBFID_00244 4.9e-12 K CsbD-like
KCKOBFID_00245 7.2e-95 nudL L hydrolase
KCKOBFID_00246 3.4e-13 nudL L hydrolase
KCKOBFID_00247 4e-19 K negative regulation of transcription, DNA-templated
KCKOBFID_00248 1.7e-23 K negative regulation of transcription, DNA-templated
KCKOBFID_00250 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
KCKOBFID_00251 1.8e-88 S Putative adhesin
KCKOBFID_00252 3.9e-161 XK27_06930 V domain protein
KCKOBFID_00253 6.4e-96 XK27_06935 K transcriptional regulator
KCKOBFID_00254 4.8e-55 ypaA M Membrane
KCKOBFID_00255 2.7e-08
KCKOBFID_00256 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCKOBFID_00257 8.2e-48 veg S Biofilm formation stimulator VEG
KCKOBFID_00258 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KCKOBFID_00259 3.9e-70 rplI J binds to the 23S rRNA
KCKOBFID_00260 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KCKOBFID_00261 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KCKOBFID_00262 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KCKOBFID_00263 0.0 S Bacterial membrane protein, YfhO
KCKOBFID_00264 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
KCKOBFID_00265 3.1e-93 lytE M LysM domain protein
KCKOBFID_00266 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCKOBFID_00267 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCKOBFID_00268 7.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCKOBFID_00269 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCKOBFID_00270 3.7e-138 ymfM S sequence-specific DNA binding
KCKOBFID_00271 1.1e-242 ymfH S Peptidase M16
KCKOBFID_00272 4.8e-235 ymfF S Peptidase M16
KCKOBFID_00273 1.6e-45 yaaA S S4 domain protein YaaA
KCKOBFID_00274 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCKOBFID_00275 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KCKOBFID_00276 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KCKOBFID_00277 1.1e-153 yvjA S membrane
KCKOBFID_00278 6.7e-306 ybiT S abc transporter atp-binding protein
KCKOBFID_00279 0.0 XK27_10405 S Bacterial membrane protein YfhO
KCKOBFID_00283 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
KCKOBFID_00284 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCKOBFID_00285 1.5e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KCKOBFID_00286 1e-134 parB K Belongs to the ParB family
KCKOBFID_00287 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCKOBFID_00288 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KCKOBFID_00289 6.6e-31 L Integrase core domain protein
KCKOBFID_00291 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCKOBFID_00292 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KCKOBFID_00293 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KCKOBFID_00294 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCKOBFID_00295 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KCKOBFID_00296 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCKOBFID_00297 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCKOBFID_00298 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KCKOBFID_00299 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCKOBFID_00300 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
KCKOBFID_00301 5.6e-240 rodA D Belongs to the SEDS family
KCKOBFID_00302 5.4e-197 L transposase, IS4 family
KCKOBFID_00303 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCKOBFID_00304 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KCKOBFID_00305 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KCKOBFID_00306 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCKOBFID_00307 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KCKOBFID_00308 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCKOBFID_00309 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCKOBFID_00310 2.9e-125 dnaD
KCKOBFID_00311 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCKOBFID_00314 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCKOBFID_00315 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
KCKOBFID_00316 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KCKOBFID_00317 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KCKOBFID_00318 3.7e-73 argR K Regulates arginine biosynthesis genes
KCKOBFID_00319 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
KCKOBFID_00320 1e-148 DegV S DegV family
KCKOBFID_00321 1.3e-143 ypmR E lipolytic protein G-D-S-L family
KCKOBFID_00322 2.1e-84 ypmS S Protein conserved in bacteria
KCKOBFID_00323 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KCKOBFID_00325 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KCKOBFID_00326 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KCKOBFID_00327 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCKOBFID_00328 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KCKOBFID_00329 2.5e-43 ysdA L Membrane
KCKOBFID_00330 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCKOBFID_00331 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCKOBFID_00332 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
KCKOBFID_00333 0.0 dnaE 2.7.7.7 L DNA polymerase
KCKOBFID_00334 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KCKOBFID_00335 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KCKOBFID_00336 1.7e-08
KCKOBFID_00338 1.2e-172 yeiH S Membrane
KCKOBFID_00339 5.1e-117 mur1 NU muramidase
KCKOBFID_00340 3.2e-35 L transposase activity
KCKOBFID_00341 2.6e-166 cpsY K Transcriptional regulator
KCKOBFID_00342 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KCKOBFID_00343 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
KCKOBFID_00344 2.4e-105 artQ P ABC transporter (Permease
KCKOBFID_00345 6.7e-47 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCKOBFID_00346 1.1e-46 aatB ET ABC transporter substrate-binding protein
KCKOBFID_00347 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCKOBFID_00348 2.1e-07
KCKOBFID_00349 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
KCKOBFID_00350 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
KCKOBFID_00351 1.1e-19 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KCKOBFID_00352 1.9e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KCKOBFID_00353 2e-126 gntR1 K transcriptional
KCKOBFID_00354 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KCKOBFID_00355 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCKOBFID_00356 2.4e-87 niaX
KCKOBFID_00357 6e-91 niaR S small molecule binding protein (contains 3H domain)
KCKOBFID_00358 9.6e-129 K DNA-binding helix-turn-helix protein
KCKOBFID_00359 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCKOBFID_00360 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCKOBFID_00361 8.2e-168 GK ROK family
KCKOBFID_00362 8.3e-159 dprA LU DNA protecting protein DprA
KCKOBFID_00363 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCKOBFID_00364 3.6e-154 S TraX protein
KCKOBFID_00365 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCKOBFID_00366 1.3e-249 T PhoQ Sensor
KCKOBFID_00367 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KCKOBFID_00368 1.1e-152 XK27_05470 E Methionine synthase
KCKOBFID_00369 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KCKOBFID_00370 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCKOBFID_00371 1.8e-51 IQ Acetoin reductase
KCKOBFID_00372 3.9e-19 IQ Acetoin reductase
KCKOBFID_00373 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KCKOBFID_00374 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCKOBFID_00377 1.3e-212 pqqE C radical SAM domain protein
KCKOBFID_00378 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KCKOBFID_00379 6.6e-61 EGP Major facilitator Superfamily
KCKOBFID_00380 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KCKOBFID_00381 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KCKOBFID_00382 1.4e-54
KCKOBFID_00383 0.0 ctpE P E1-E2 ATPase
KCKOBFID_00384 3.9e-26
KCKOBFID_00385 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCKOBFID_00386 5.1e-47 L transposase activity
KCKOBFID_00387 1.4e-81 K transcriptional regulator, MerR family
KCKOBFID_00388 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
KCKOBFID_00389 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
KCKOBFID_00390 7.4e-64 XK27_02560 S cog cog2151
KCKOBFID_00391 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCKOBFID_00392 7.7e-227 ytfP S Flavoprotein
KCKOBFID_00394 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KCKOBFID_00395 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
KCKOBFID_00396 2.7e-183 ecsB U ABC transporter
KCKOBFID_00397 2.3e-133 ecsA V abc transporter atp-binding protein
KCKOBFID_00398 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KCKOBFID_00399 6e-11
KCKOBFID_00400 1.3e-56 S CD20-like family
KCKOBFID_00401 3.2e-110
KCKOBFID_00402 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KCKOBFID_00403 6.9e-206 ylbM S Belongs to the UPF0348 family
KCKOBFID_00404 2e-140 yqeM Q Methyltransferase domain protein
KCKOBFID_00405 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KCKOBFID_00406 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KCKOBFID_00407 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCKOBFID_00408 3.5e-49 yhbY J RNA-binding protein
KCKOBFID_00409 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KCKOBFID_00410 1.8e-98 yqeG S hydrolase of the HAD superfamily
KCKOBFID_00411 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KCKOBFID_00412 5.8e-24
KCKOBFID_00413 3.5e-13
KCKOBFID_00414 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCKOBFID_00415 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KCKOBFID_00416 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCKOBFID_00417 1.3e-251 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCKOBFID_00418 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCKOBFID_00419 1.6e-154 hlpA M Belongs to the NlpA lipoprotein family
KCKOBFID_00420 6.8e-101 pncA Q isochorismatase
KCKOBFID_00421 6.8e-139 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCKOBFID_00422 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KCKOBFID_00423 2.4e-75 XK27_03180 T universal stress protein
KCKOBFID_00426 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCKOBFID_00427 3.9e-41 3.6.1.55 F NUDIX domain
KCKOBFID_00429 3.7e-122 S An automated process has identified a potential problem with this gene model
KCKOBFID_00430 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
KCKOBFID_00431 1.6e-14 liaI KT membrane
KCKOBFID_00432 2.6e-30 liaI KT membrane
KCKOBFID_00433 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
KCKOBFID_00434 0.0 V ABC transporter (permease)
KCKOBFID_00435 5.8e-135 macB2 V ABC transporter, ATP-binding protein
KCKOBFID_00436 6.2e-166 T Histidine kinase
KCKOBFID_00437 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCKOBFID_00438 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KCKOBFID_00440 3.3e-69 pbuX F xanthine permease
KCKOBFID_00441 9.2e-119 pbuX F xanthine permease
KCKOBFID_00442 5.3e-248 norM V Multidrug efflux pump
KCKOBFID_00443 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCKOBFID_00444 7.8e-236 brnQ E Component of the transport system for branched-chain amino acids
KCKOBFID_00445 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCKOBFID_00446 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCKOBFID_00447 9.6e-26 csbD K CsbD-like
KCKOBFID_00448 1.5e-245 yfnA E amino acid
KCKOBFID_00449 6.1e-111 XK27_02070 S nitroreductase
KCKOBFID_00450 2.1e-154 1.13.11.2 S glyoxalase
KCKOBFID_00451 3.3e-77 ywnA K Transcriptional regulator
KCKOBFID_00452 6.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
KCKOBFID_00453 2.4e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KCKOBFID_00454 1.3e-111 drgA C Nitroreductase
KCKOBFID_00455 2.4e-75 yoaK S Protein of unknown function (DUF1275)
KCKOBFID_00456 3.1e-161 yvgN C reductase
KCKOBFID_00457 5.6e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCKOBFID_00458 2.4e-09
KCKOBFID_00459 1.6e-140 S Abortive infection C-terminus
KCKOBFID_00460 0.0 L DEAD-like helicases superfamily
KCKOBFID_00461 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KCKOBFID_00462 2.7e-285 XK27_07020 S Belongs to the UPF0371 family
KCKOBFID_00464 1.1e-37 BP1961 P nitric oxide dioxygenase activity
KCKOBFID_00465 1.6e-53 K response regulator
KCKOBFID_00466 9.3e-72 S Signal peptide protein, YSIRK family
KCKOBFID_00467 4.5e-61
KCKOBFID_00468 5.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCKOBFID_00469 1.9e-35
KCKOBFID_00470 1.2e-165 L integrase core domain
KCKOBFID_00471 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCKOBFID_00472 3.5e-143 pts33BCA G pts system
KCKOBFID_00473 5.8e-71 pts33BCA G pts system
KCKOBFID_00474 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
KCKOBFID_00475 1.8e-254 cycA E permease
KCKOBFID_00476 4.5e-39 ynzC S UPF0291 protein
KCKOBFID_00477 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KCKOBFID_00478 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KCKOBFID_00479 6.1e-63 S membrane
KCKOBFID_00480 1.5e-59
KCKOBFID_00481 7.5e-26
KCKOBFID_00482 1.8e-53
KCKOBFID_00483 1.9e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCKOBFID_00484 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
KCKOBFID_00485 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KCKOBFID_00486 4.9e-106 mur1 NU mannosyl-glycoprotein
KCKOBFID_00487 1.1e-53 glnB K Belongs to the P(II) protein family
KCKOBFID_00488 2.6e-233 amt P Ammonium Transporter
KCKOBFID_00489 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KCKOBFID_00490 9.5e-55 yabA L Involved in initiation control of chromosome replication
KCKOBFID_00491 1.2e-135 yaaT S stage 0 sporulation protein
KCKOBFID_00492 6.4e-162 holB 2.7.7.7 L dna polymerase iii
KCKOBFID_00493 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCKOBFID_00494 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KCKOBFID_00495 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCKOBFID_00496 2.8e-230 ftsW D Belongs to the SEDS family
KCKOBFID_00497 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KCKOBFID_00498 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCKOBFID_00499 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCKOBFID_00500 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCKOBFID_00501 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCKOBFID_00502 3.3e-78 atpF C ATP synthase F(0) sector subunit b
KCKOBFID_00503 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KCKOBFID_00504 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCKOBFID_00505 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KCKOBFID_00506 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCKOBFID_00507 6.6e-147 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KCKOBFID_00508 8.9e-14 coiA 3.6.4.12 S Competence protein
KCKOBFID_00509 2.2e-15 T peptidase
KCKOBFID_00510 5.5e-153 rarD S Transporter
KCKOBFID_00511 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KCKOBFID_00512 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KCKOBFID_00513 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KCKOBFID_00514 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KCKOBFID_00515 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCKOBFID_00516 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KCKOBFID_00517 1.5e-103 yjbK S Adenylate cyclase
KCKOBFID_00518 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCKOBFID_00519 2.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
KCKOBFID_00520 3.1e-59 XK27_04120 S Putative amino acid metabolism
KCKOBFID_00521 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KCKOBFID_00522 7.2e-132 puuD T peptidase C26
KCKOBFID_00523 1.2e-115 radC E Belongs to the UPF0758 family
KCKOBFID_00524 1.7e-268 M Psort location CytoplasmicMembrane, score
KCKOBFID_00525 0.0 rgpF M Rhamnan synthesis protein F
KCKOBFID_00526 2e-305 GT4 M transferase activity, transferring glycosyl groups
KCKOBFID_00527 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KCKOBFID_00528 2.1e-143 rgpC GM Transport permease protein
KCKOBFID_00529 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
KCKOBFID_00530 1.8e-228 rgpA GT4 M Domain of unknown function (DUF1972)
KCKOBFID_00531 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
KCKOBFID_00532 4.6e-42 S Uncharacterized conserved protein (DUF2304)
KCKOBFID_00533 6.9e-130 arnC M group 2 family protein
KCKOBFID_00534 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
KCKOBFID_00535 9.3e-186 S Glycosyltransferase like family 2
KCKOBFID_00536 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
KCKOBFID_00537 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KCKOBFID_00538 5.3e-237 S Predicted membrane protein (DUF2142)
KCKOBFID_00539 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KCKOBFID_00540 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KCKOBFID_00541 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KCKOBFID_00542 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KCKOBFID_00543 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KCKOBFID_00544 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
KCKOBFID_00545 1.6e-202 arcT 2.6.1.1 E Aminotransferase
KCKOBFID_00546 6.5e-137 ET ABC transporter
KCKOBFID_00547 7.5e-144 ET Belongs to the bacterial solute-binding protein 3 family
KCKOBFID_00548 2.9e-84 mutT 3.6.1.55 F Nudix family
KCKOBFID_00549 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KCKOBFID_00550 2.5e-56 V CAAX protease self-immunity
KCKOBFID_00551 2.4e-33 S CAAX amino terminal protease family protein
KCKOBFID_00552 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KCKOBFID_00553 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCKOBFID_00554 1.1e-16 XK27_00735
KCKOBFID_00555 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCKOBFID_00557 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCKOBFID_00560 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
KCKOBFID_00561 4.7e-51 ycaO O OsmC-like protein
KCKOBFID_00562 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
KCKOBFID_00564 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
KCKOBFID_00565 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCKOBFID_00566 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCKOBFID_00567 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KCKOBFID_00568 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
KCKOBFID_00569 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KCKOBFID_00570 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCKOBFID_00571 2.6e-109 3.1.3.18 S IA, variant 1
KCKOBFID_00572 2.2e-117 lrgB M effector of murein hydrolase
KCKOBFID_00573 7.7e-56 lrgA S Effector of murein hydrolase LrgA
KCKOBFID_00575 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
KCKOBFID_00576 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KCKOBFID_00577 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCKOBFID_00578 3.9e-104 wecD M Acetyltransferase GNAT family
KCKOBFID_00579 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCKOBFID_00580 4.6e-58 GK ROK family
KCKOBFID_00581 2.1e-25 GK ROK family
KCKOBFID_00582 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
KCKOBFID_00583 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
KCKOBFID_00584 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
KCKOBFID_00585 2.3e-206 potD P spermidine putrescine ABC transporter
KCKOBFID_00586 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
KCKOBFID_00587 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
KCKOBFID_00588 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KCKOBFID_00589 7.8e-171 murB 1.3.1.98 M cell wall formation
KCKOBFID_00590 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCKOBFID_00591 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCKOBFID_00592 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KCKOBFID_00593 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCKOBFID_00594 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
KCKOBFID_00595 0.0 ydaO E amino acid
KCKOBFID_00596 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCKOBFID_00597 4.1e-37 ylqC L Belongs to the UPF0109 family
KCKOBFID_00598 1.6e-42 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KCKOBFID_00599 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KCKOBFID_00600 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
KCKOBFID_00601 2.1e-74 S QueT transporter
KCKOBFID_00602 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KCKOBFID_00603 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KCKOBFID_00604 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KCKOBFID_00605 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCKOBFID_00606 2.2e-85 ccl S cog cog4708
KCKOBFID_00607 5.8e-161 rbn E Belongs to the UPF0761 family
KCKOBFID_00608 1.9e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KCKOBFID_00609 3e-232 ytoI K transcriptional regulator containing CBS domains
KCKOBFID_00610 1.1e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KCKOBFID_00611 1.5e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCKOBFID_00612 0.0 comEC S Competence protein ComEC
KCKOBFID_00613 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KCKOBFID_00614 1.7e-142 plsC 2.3.1.51 I Acyltransferase
KCKOBFID_00615 1.8e-140 nodB3 G deacetylase
KCKOBFID_00616 7.1e-141 yabB 2.1.1.223 L Methyltransferase
KCKOBFID_00617 1e-41 yazA L endonuclease containing a URI domain
KCKOBFID_00618 2.4e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KCKOBFID_00619 2.3e-154 corA P CorA-like protein
KCKOBFID_00620 1.9e-62 yjqA S Bacterial PH domain
KCKOBFID_00621 2.3e-99 thiT S Thiamine transporter
KCKOBFID_00622 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCKOBFID_00623 1.9e-201 yjbB G Permeases of the major facilitator superfamily
KCKOBFID_00624 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCKOBFID_00625 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
KCKOBFID_00626 1e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KCKOBFID_00630 1.1e-155 cjaA ET ABC transporter substrate-binding protein
KCKOBFID_00631 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCKOBFID_00632 3.5e-115 P ABC transporter (Permease
KCKOBFID_00633 1e-114 papP P ABC transporter (Permease
KCKOBFID_00634 1.5e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KCKOBFID_00635 6.5e-63 manO S protein conserved in bacteria
KCKOBFID_00636 1.9e-169 manN G PTS system mannose fructose sorbose family IID component
KCKOBFID_00637 7e-118 manM G pts system
KCKOBFID_00638 1.3e-174 manL 2.7.1.191 G pts system
KCKOBFID_00639 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KCKOBFID_00640 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KCKOBFID_00641 1.9e-248 pbuO S permease
KCKOBFID_00642 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KCKOBFID_00643 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
KCKOBFID_00644 2.5e-220 brpA K Transcriptional
KCKOBFID_00645 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KCKOBFID_00646 3.1e-212 nusA K Participates in both transcription termination and antitermination
KCKOBFID_00647 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KCKOBFID_00648 1.4e-41 ylxQ J ribosomal protein
KCKOBFID_00649 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCKOBFID_00650 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KCKOBFID_00651 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
KCKOBFID_00652 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
KCKOBFID_00653 3.2e-214 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KCKOBFID_00654 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCKOBFID_00655 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KCKOBFID_00656 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KCKOBFID_00657 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
KCKOBFID_00658 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KCKOBFID_00660 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KCKOBFID_00661 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCKOBFID_00662 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KCKOBFID_00663 3.4e-74 ylbF S Belongs to the UPF0342 family
KCKOBFID_00664 7.1e-46 ylbG S UPF0298 protein
KCKOBFID_00665 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KCKOBFID_00666 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KCKOBFID_00667 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
KCKOBFID_00668 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KCKOBFID_00669 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KCKOBFID_00670 1.1e-69 acuB S IMP dehydrogenase activity
KCKOBFID_00671 3.3e-43 acuB S IMP dehydrogenase activity
KCKOBFID_00672 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KCKOBFID_00673 6.3e-111 yvyE 3.4.13.9 S YigZ family
KCKOBFID_00674 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KCKOBFID_00675 4.4e-123 comFC S Competence protein
KCKOBFID_00676 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KCKOBFID_00677 6.6e-81 ET amino acid transport
KCKOBFID_00678 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCKOBFID_00679 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
KCKOBFID_00680 3.8e-205 EGP Transmembrane secretion effector
KCKOBFID_00681 1.8e-153 ET amino acid transport
KCKOBFID_00682 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
KCKOBFID_00683 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KCKOBFID_00684 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KCKOBFID_00685 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KCKOBFID_00686 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCKOBFID_00687 3e-98 metI P ABC transporter (Permease
KCKOBFID_00688 2.7e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KCKOBFID_00689 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KCKOBFID_00690 9.4e-95 S UPF0397 protein
KCKOBFID_00691 0.0 ykoD P abc transporter atp-binding protein
KCKOBFID_00692 1.2e-149 cbiQ P cobalt transport
KCKOBFID_00693 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCKOBFID_00694 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
KCKOBFID_00695 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
KCKOBFID_00696 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
KCKOBFID_00697 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KCKOBFID_00698 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
KCKOBFID_00699 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCKOBFID_00700 2.8e-282 T PhoQ Sensor
KCKOBFID_00701 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCKOBFID_00702 6.5e-218 dnaB L Replication initiation and membrane attachment
KCKOBFID_00703 5.2e-167 dnaI L Primosomal protein DnaI
KCKOBFID_00704 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KCKOBFID_00706 1.2e-34
KCKOBFID_00707 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
KCKOBFID_00708 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
KCKOBFID_00709 3.1e-172 yxaM EGP Major facilitator Superfamily
KCKOBFID_00710 8.8e-83 adk 2.7.4.3 F topology modulation protein
KCKOBFID_00711 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCKOBFID_00712 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCKOBFID_00713 1.7e-35 XK27_09805 S MORN repeat protein
KCKOBFID_00714 0.0 XK27_09800 I Acyltransferase
KCKOBFID_00715 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KCKOBFID_00716 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KCKOBFID_00717 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCKOBFID_00718 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
KCKOBFID_00719 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KCKOBFID_00720 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCKOBFID_00721 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KCKOBFID_00722 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KCKOBFID_00723 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KCKOBFID_00724 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KCKOBFID_00725 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KCKOBFID_00726 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCKOBFID_00727 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCKOBFID_00728 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCKOBFID_00729 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCKOBFID_00730 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCKOBFID_00731 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCKOBFID_00732 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KCKOBFID_00733 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCKOBFID_00734 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCKOBFID_00735 2.5e-23 rpmD J ribosomal protein l30
KCKOBFID_00736 4.4e-58 rplO J binds to the 23S rRNA
KCKOBFID_00737 2.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KCKOBFID_00738 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KCKOBFID_00739 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KCKOBFID_00740 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KCKOBFID_00741 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KCKOBFID_00742 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCKOBFID_00743 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCKOBFID_00744 3.3e-62 rplQ J ribosomal protein l17
KCKOBFID_00745 1.8e-111 L PFAM Integrase, catalytic core
KCKOBFID_00746 3.3e-09 L PFAM Integrase, catalytic core
KCKOBFID_00747 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
KCKOBFID_00748 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
KCKOBFID_00749 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
KCKOBFID_00751 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
KCKOBFID_00752 4.2e-72 L PFAM Integrase, catalytic core
KCKOBFID_00753 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KCKOBFID_00754 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KCKOBFID_00755 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
KCKOBFID_00756 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
KCKOBFID_00757 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCKOBFID_00758 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCKOBFID_00759 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCKOBFID_00760 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KCKOBFID_00761 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
KCKOBFID_00762 0.0 pepF E oligoendopeptidase F
KCKOBFID_00763 1.4e-186 coiA 3.6.4.12 S Competence protein
KCKOBFID_00764 1.8e-167 K transcriptional regulator (lysR family)
KCKOBFID_00765 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCKOBFID_00769 8e-191 phoH T phosphate starvation-inducible protein PhoH
KCKOBFID_00770 2.3e-61 rlpA M LysM domain protein
KCKOBFID_00771 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KCKOBFID_00772 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCKOBFID_00773 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
KCKOBFID_00774 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KCKOBFID_00775 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KCKOBFID_00777 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCKOBFID_00779 6.5e-63 KT phosphorelay signal transduction system
KCKOBFID_00780 1.9e-80 S Protein of unknown function (DUF3021)
KCKOBFID_00781 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCKOBFID_00782 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KCKOBFID_00783 8.2e-70 argR K Regulates arginine biosynthesis genes
KCKOBFID_00784 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KCKOBFID_00785 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCKOBFID_00786 9.2e-141 1.1.1.169 H Ketopantoate reductase
KCKOBFID_00787 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KCKOBFID_00788 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCKOBFID_00789 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
KCKOBFID_00790 2.3e-161 S CHAP domain
KCKOBFID_00791 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCKOBFID_00792 1.8e-135 divIVA D Cell division protein DivIVA
KCKOBFID_00793 4.2e-144 ylmH T S4 RNA-binding domain
KCKOBFID_00794 2e-34 yggT D integral membrane protein
KCKOBFID_00795 1.4e-96 sepF D cell septum assembly
KCKOBFID_00796 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCKOBFID_00797 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCKOBFID_00798 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KCKOBFID_00799 6.7e-172 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KCKOBFID_00800 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCKOBFID_00801 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCKOBFID_00803 0.0 typA T GTP-binding protein TypA
KCKOBFID_00804 2.2e-179 glk 2.7.1.2 G Glucokinase
KCKOBFID_00805 8.4e-28 yqgQ S protein conserved in bacteria
KCKOBFID_00806 1.1e-80 perR P Belongs to the Fur family
KCKOBFID_00807 3.2e-92 dps P Belongs to the Dps family
KCKOBFID_00808 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KCKOBFID_00809 4.8e-196 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KCKOBFID_00810 1.6e-32 L Integrase core domain protein
KCKOBFID_00811 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KCKOBFID_00812 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCKOBFID_00813 4.6e-238 dltB M Membrane protein involved in D-alanine export
KCKOBFID_00814 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCKOBFID_00815 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
KCKOBFID_00816 0.0 XK27_10035 V abc transporter atp-binding protein
KCKOBFID_00817 0.0 yfiB1 V abc transporter atp-binding protein
KCKOBFID_00818 6e-106 pvaA M lytic transglycosylase activity
KCKOBFID_00819 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KCKOBFID_00820 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCKOBFID_00821 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KCKOBFID_00822 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KCKOBFID_00823 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCKOBFID_00824 4.5e-111 tdk 2.7.1.21 F thymidine kinase
KCKOBFID_00825 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KCKOBFID_00826 2.4e-155 gst O Glutathione S-transferase
KCKOBFID_00827 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KCKOBFID_00828 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KCKOBFID_00829 2e-45 rpmE2 J 50S ribosomal protein L31
KCKOBFID_00830 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
KCKOBFID_00831 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCKOBFID_00832 2.1e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCKOBFID_00833 7.5e-23 I Alpha/beta hydrolase family
KCKOBFID_00834 1.5e-35 yugF I carboxylic ester hydrolase activity
KCKOBFID_00835 2.2e-45 K sequence-specific DNA binding
KCKOBFID_00836 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCKOBFID_00837 1.5e-07
KCKOBFID_00838 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KCKOBFID_00839 1.1e-78 feoA P FeoA domain protein
KCKOBFID_00840 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCKOBFID_00841 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KCKOBFID_00842 1.3e-34 ykuJ S protein conserved in bacteria
KCKOBFID_00843 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCKOBFID_00844 0.0 clpE O Belongs to the ClpA ClpB family
KCKOBFID_00845 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KCKOBFID_00846 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
KCKOBFID_00847 2.4e-66 S oxidoreductase
KCKOBFID_00848 1.5e-50 S oxidoreductase
KCKOBFID_00849 6.8e-234 murN 2.3.2.10, 2.3.2.16 V FemAB family
KCKOBFID_00850 1.7e-63 M Pfam SNARE associated Golgi protein
KCKOBFID_00851 1.5e-30 S Domain of Unknown Function with PDB structure (DUF3862)
KCKOBFID_00852 1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
KCKOBFID_00855 6.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
KCKOBFID_00856 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCKOBFID_00857 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KCKOBFID_00858 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KCKOBFID_00859 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
KCKOBFID_00860 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
KCKOBFID_00861 2.3e-27
KCKOBFID_00862 7.6e-146 S ABC-2 family transporter protein
KCKOBFID_00863 4.1e-150 S transport system, permease component
KCKOBFID_00864 1.8e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCKOBFID_00865 4.2e-195 desK 2.7.13.3 T Histidine kinase
KCKOBFID_00866 7.4e-135 yvfS V ABC-2 type transporter
KCKOBFID_00867 2.1e-160 XK27_09825 V 'abc transporter, ATP-binding protein
KCKOBFID_00871 2.3e-213 EGP Major facilitator Superfamily
KCKOBFID_00872 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
KCKOBFID_00873 2.9e-61 mutR K Transcriptional activator, Rgg GadR MutR family
KCKOBFID_00874 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCKOBFID_00875 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KCKOBFID_00876 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCKOBFID_00877 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KCKOBFID_00878 1.5e-97 ybhL S Belongs to the BI1 family
KCKOBFID_00881 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KCKOBFID_00882 9.6e-92 K transcriptional regulator
KCKOBFID_00883 7.6e-36 yneF S UPF0154 protein
KCKOBFID_00884 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KCKOBFID_00885 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCKOBFID_00886 3.5e-99 XK27_09740 S Phosphoesterase
KCKOBFID_00887 5.4e-86 ykuL S CBS domain
KCKOBFID_00888 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KCKOBFID_00889 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCKOBFID_00890 2.3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCKOBFID_00891 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCKOBFID_00892 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KCKOBFID_00893 1.2e-258 trkH P Cation transport protein
KCKOBFID_00894 1.8e-248 trkA P Potassium transporter peripheral membrane component
KCKOBFID_00895 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KCKOBFID_00896 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KCKOBFID_00897 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KCKOBFID_00898 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KCKOBFID_00899 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCKOBFID_00901 9.2e-43 licT K transcriptional antiterminator
KCKOBFID_00902 6.8e-53 licT K transcriptional antiterminator
KCKOBFID_00903 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KCKOBFID_00904 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KCKOBFID_00905 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCKOBFID_00906 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KCKOBFID_00907 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCKOBFID_00908 6e-133 mdtG EGP Major facilitator Superfamily
KCKOBFID_00909 9.5e-74 mdtG EGP Major facilitator Superfamily
KCKOBFID_00910 2.6e-33 secG U Preprotein translocase subunit SecG
KCKOBFID_00911 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KCKOBFID_00912 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KCKOBFID_00913 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCKOBFID_00914 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KCKOBFID_00915 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KCKOBFID_00916 4.4e-183 ccpA K Catabolite control protein A
KCKOBFID_00917 2.8e-28 yyaQ S YjbR
KCKOBFID_00918 6.6e-101 yyaQ V Protein conserved in bacteria
KCKOBFID_00919 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KCKOBFID_00920 1e-78 yueI S Protein of unknown function (DUF1694)
KCKOBFID_00921 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KCKOBFID_00922 2e-25 WQ51_00785
KCKOBFID_00923 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KCKOBFID_00924 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
KCKOBFID_00925 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KCKOBFID_00926 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCKOBFID_00927 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCKOBFID_00928 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KCKOBFID_00929 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KCKOBFID_00930 3.2e-53 yheA S Belongs to the UPF0342 family
KCKOBFID_00931 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KCKOBFID_00932 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KCKOBFID_00933 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCKOBFID_00934 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
KCKOBFID_00935 2.6e-253 msrR K Transcriptional regulator
KCKOBFID_00936 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
KCKOBFID_00937 2.4e-203 I acyl-CoA dehydrogenase
KCKOBFID_00938 3.5e-97 mip S hydroperoxide reductase activity
KCKOBFID_00939 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCKOBFID_00940 8.9e-20
KCKOBFID_00941 3.2e-46
KCKOBFID_00942 1e-31 K Cro/C1-type HTH DNA-binding domain
KCKOBFID_00943 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KCKOBFID_00944 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
KCKOBFID_00945 4.4e-93
KCKOBFID_00946 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KCKOBFID_00947 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCKOBFID_00948 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCKOBFID_00949 2.3e-198 S CRISPR-associated protein Csn2 subfamily St
KCKOBFID_00950 1.3e-148 ycgQ S TIGR03943 family
KCKOBFID_00951 1.7e-157 XK27_03015 S permease
KCKOBFID_00953 0.0 yhgF K Transcriptional accessory protein
KCKOBFID_00954 9.9e-42 pspC KT PspC domain
KCKOBFID_00955 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KCKOBFID_00956 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCKOBFID_00958 5.5e-69 ytxH S General stress protein
KCKOBFID_00960 4.4e-177 yegQ O Peptidase U32
KCKOBFID_00961 3.4e-252 yegQ O Peptidase U32
KCKOBFID_00962 1.5e-89 bioY S biotin synthase
KCKOBFID_00964 1.1e-33 XK27_12190 S protein conserved in bacteria
KCKOBFID_00965 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
KCKOBFID_00966 1.9e-12
KCKOBFID_00967 5e-237 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KCKOBFID_00968 4.2e-117
KCKOBFID_00969 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KCKOBFID_00970 1e-163 M LysM domain
KCKOBFID_00971 7.6e-16
KCKOBFID_00972 2.3e-175 S hydrolase
KCKOBFID_00973 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KCKOBFID_00974 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCKOBFID_00975 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KCKOBFID_00976 2.7e-27 P Hemerythrin HHE cation binding domain protein
KCKOBFID_00977 1.6e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCKOBFID_00978 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
KCKOBFID_00979 9.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
KCKOBFID_00980 8.7e-45 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCKOBFID_00981 7.6e-71 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCKOBFID_00982 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KCKOBFID_00983 1.2e-216 S Bacteriophage abortive infection AbiH
KCKOBFID_00985 2.8e-221 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
KCKOBFID_00986 2.2e-105
KCKOBFID_00987 1e-136 S Protein conserved in bacteria
KCKOBFID_00988 6.6e-306 hsdM 2.1.1.72 V type I restriction-modification system
KCKOBFID_00989 5.9e-22 S PD-(D/E)XK nuclease family transposase
KCKOBFID_00990 1e-36 spd F DNA RNA non-specific endonuclease
KCKOBFID_00991 9.9e-90 spd F DNA RNA non-specific endonuclease
KCKOBFID_00992 9e-93 lemA S LemA family
KCKOBFID_00993 6.4e-133 htpX O Belongs to the peptidase M48B family
KCKOBFID_00994 1.8e-73 S Psort location CytoplasmicMembrane, score
KCKOBFID_00995 6.2e-56 S Domain of unknown function (DUF4430)
KCKOBFID_00996 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KCKOBFID_00997 1.9e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
KCKOBFID_00998 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KCKOBFID_00999 3e-44 ymbI L transposase activity
KCKOBFID_01000 4e-22 L Belongs to the 'phage' integrase family
KCKOBFID_01001 1.4e-66 S tRNA_anti-like
KCKOBFID_01002 2e-103
KCKOBFID_01004 5e-12
KCKOBFID_01006 2e-296 S DNA primase
KCKOBFID_01007 3e-164 KL Phage plasmid primase P4 family
KCKOBFID_01008 6.9e-22
KCKOBFID_01009 9.2e-13
KCKOBFID_01014 1.3e-17 K Cro/C1-type HTH DNA-binding domain
KCKOBFID_01016 1.1e-220 sip L Belongs to the 'phage' integrase family
KCKOBFID_01018 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCKOBFID_01019 7.3e-166 metF 1.5.1.20 E reductase
KCKOBFID_01020 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KCKOBFID_01021 1.7e-94 panT S ECF transporter, substrate-specific component
KCKOBFID_01022 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCKOBFID_01023 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KCKOBFID_01024 3.5e-28 3.4.13.21 I Protein conserved in bacteria
KCKOBFID_01025 8.1e-90 FNV0100 F Belongs to the Nudix hydrolase family
KCKOBFID_01026 3.7e-190
KCKOBFID_01027 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KCKOBFID_01029 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
KCKOBFID_01030 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
KCKOBFID_01031 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KCKOBFID_01032 1.2e-143 2.4.2.3 F Phosphorylase superfamily
KCKOBFID_01035 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
KCKOBFID_01036 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
KCKOBFID_01037 6e-08 S Hydrolases of the alpha beta superfamily
KCKOBFID_01038 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KCKOBFID_01039 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KCKOBFID_01040 1.8e-159 czcD P cation diffusion facilitator family transporter
KCKOBFID_01041 9e-98 K Transcriptional regulator, TetR family
KCKOBFID_01042 1.6e-10
KCKOBFID_01043 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KCKOBFID_01044 6.4e-104 V ABC transporter (Permease
KCKOBFID_01045 0.0
KCKOBFID_01047 1.5e-35 K sequence-specific DNA binding
KCKOBFID_01048 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KCKOBFID_01049 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCKOBFID_01050 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCKOBFID_01051 1.8e-31 K helix-turn-helix
KCKOBFID_01052 3.4e-155 degV S DegV family
KCKOBFID_01053 3.5e-91 yacP S RNA-binding protein containing a PIN domain
KCKOBFID_01054 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCKOBFID_01057 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCKOBFID_01058 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCKOBFID_01059 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
KCKOBFID_01060 6.9e-144 S SseB protein N-terminal domain
KCKOBFID_01061 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KCKOBFID_01062 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCKOBFID_01063 9e-08
KCKOBFID_01064 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KCKOBFID_01065 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KCKOBFID_01066 3.1e-81 ypmB S Protein conserved in bacteria
KCKOBFID_01067 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KCKOBFID_01068 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KCKOBFID_01069 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KCKOBFID_01070 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
KCKOBFID_01071 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KCKOBFID_01072 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KCKOBFID_01073 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KCKOBFID_01074 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCKOBFID_01075 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCKOBFID_01076 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KCKOBFID_01077 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KCKOBFID_01078 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
KCKOBFID_01079 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
KCKOBFID_01080 2.1e-30 rpsT J rRNA binding
KCKOBFID_01082 2.7e-95 S Hydrophobic domain protein
KCKOBFID_01083 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
KCKOBFID_01085 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KCKOBFID_01086 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KCKOBFID_01087 9.2e-36 metE 2.1.1.14 E Methionine synthase
KCKOBFID_01088 7.6e-64 metE 2.1.1.14 E Methionine synthase
KCKOBFID_01089 5.7e-52 metE 2.1.1.14 E Methionine synthase
KCKOBFID_01090 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
KCKOBFID_01092 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KCKOBFID_01093 9.9e-169 XK27_01785 S cog cog1284
KCKOBFID_01094 1.8e-147 yaaA S Belongs to the UPF0246 family
KCKOBFID_01095 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCKOBFID_01096 2.6e-91 XK27_10930 K acetyltransferase
KCKOBFID_01097 7.5e-14
KCKOBFID_01098 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KCKOBFID_01099 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
KCKOBFID_01100 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KCKOBFID_01101 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCKOBFID_01102 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KCKOBFID_01103 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KCKOBFID_01104 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCKOBFID_01105 5.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KCKOBFID_01106 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCKOBFID_01107 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KCKOBFID_01108 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
KCKOBFID_01109 5.9e-219 araT 2.6.1.1 E Aminotransferase
KCKOBFID_01110 2.5e-26
KCKOBFID_01111 2e-169 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCKOBFID_01112 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
KCKOBFID_01113 1.8e-57 asp S cog cog1302
KCKOBFID_01114 3.2e-226 norN V Mate efflux family protein
KCKOBFID_01115 9.2e-278 thrC 4.2.3.1 E Threonine synthase
KCKOBFID_01116 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCKOBFID_01117 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
KCKOBFID_01118 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCKOBFID_01119 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCKOBFID_01120 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
KCKOBFID_01121 0.0 pepO 3.4.24.71 O Peptidase family M13
KCKOBFID_01122 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCKOBFID_01123 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCKOBFID_01124 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCKOBFID_01125 1.4e-54 treB 2.7.1.201 G PTS System
KCKOBFID_01126 5.8e-21 treR K DNA-binding transcription factor activity
KCKOBFID_01127 1.2e-85 treR K trehalose operon
KCKOBFID_01128 3.3e-95 ywlG S Belongs to the UPF0340 family
KCKOBFID_01130 1.6e-24 U response to pH
KCKOBFID_01131 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KCKOBFID_01132 2.1e-204 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KCKOBFID_01133 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KCKOBFID_01134 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KCKOBFID_01135 1.9e-77 K DNA-binding transcription factor activity
KCKOBFID_01136 0.0 lmrA1 V abc transporter atp-binding protein
KCKOBFID_01137 0.0 lmrA2 V abc transporter atp-binding protein
KCKOBFID_01138 1.6e-44 K Acetyltransferase (GNAT) family
KCKOBFID_01139 2.9e-120 sptS 2.7.13.3 T Histidine kinase
KCKOBFID_01140 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KCKOBFID_01141 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KCKOBFID_01142 5.3e-161 cvfB S Protein conserved in bacteria
KCKOBFID_01143 7.4e-35 yozE S Belongs to the UPF0346 family
KCKOBFID_01144 7.8e-143 S Macro domain protein
KCKOBFID_01145 4.8e-51 trxA O Belongs to the thioredoxin family
KCKOBFID_01146 2.5e-26 yccU S CoA-binding protein
KCKOBFID_01147 1.4e-144 tatD L Hydrolase, tatd
KCKOBFID_01148 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KCKOBFID_01149 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KCKOBFID_01151 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KCKOBFID_01152 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KCKOBFID_01153 1.8e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
KCKOBFID_01154 6.9e-173 rmuC S RmuC domain protein
KCKOBFID_01155 1.8e-178 cbf S 3'-5' exoribonuclease yhaM
KCKOBFID_01156 1.1e-142 purR 2.4.2.7 F operon repressor
KCKOBFID_01157 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCKOBFID_01158 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KCKOBFID_01159 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCKOBFID_01160 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KCKOBFID_01161 4.2e-44 yrzB S Belongs to the UPF0473 family
KCKOBFID_01162 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCKOBFID_01163 2.8e-44 yrzL S Belongs to the UPF0297 family
KCKOBFID_01164 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KCKOBFID_01165 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KCKOBFID_01167 3.5e-216 int L Belongs to the 'phage' integrase family
KCKOBFID_01168 1.9e-18 S Domain of unknown function (DUF3173)
KCKOBFID_01169 1.4e-107 L Replication initiation factor
KCKOBFID_01170 1e-36 L Replication initiation factor
KCKOBFID_01171 1.7e-90 K sequence-specific DNA binding
KCKOBFID_01172 3.9e-287 V ABC transporter transmembrane region
KCKOBFID_01173 3.4e-191 C Radical SAM
KCKOBFID_01175 1.4e-127 Z012_04635 K sequence-specific DNA binding
KCKOBFID_01176 2.1e-280 V ABC transporter
KCKOBFID_01177 2e-126 KLT serine threonine protein kinase
KCKOBFID_01178 1.1e-183 M Glycosyltransferase, group 2 family protein
KCKOBFID_01180 5.8e-202 cps1B GT2,GT4 M Glycosyl transferases group 1
KCKOBFID_01181 7.6e-174 rgpB GT2 S Glycosyl transferase family 2
KCKOBFID_01182 4.6e-202 GT4 M Glycosyltransferase, group 1 family protein
KCKOBFID_01183 2e-91 pssE S Glycosyltransferase family 28 C-terminal domain
KCKOBFID_01184 3.3e-88 cpsF M Oligosaccharide biosynthesis protein Alg14 like
KCKOBFID_01185 2.4e-31 rgpAc GT4 M Domain of unknown function (DUF1972)
KCKOBFID_01186 2.4e-256 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KCKOBFID_01187 9.7e-119 cpsD D COG0489 ATPases involved in chromosome partitioning
KCKOBFID_01188 1.9e-116 cps4C M biosynthesis protein
KCKOBFID_01189 4.6e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KCKOBFID_01190 8e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KCKOBFID_01191 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KCKOBFID_01192 1.5e-30 yfeJ 6.3.5.2 F glutamine amidotransferase
KCKOBFID_01193 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
KCKOBFID_01194 9.4e-66 clcA_2 P chloride
KCKOBFID_01195 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCKOBFID_01196 8.1e-41 S Protein of unknown function (DUF1697)
KCKOBFID_01197 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KCKOBFID_01198 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCKOBFID_01200 6.1e-22 V Glucan-binding protein C
KCKOBFID_01201 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
KCKOBFID_01202 2.1e-276 pepV 3.5.1.18 E Dipeptidase
KCKOBFID_01203 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KCKOBFID_01204 6.9e-86 XK27_03610 K Gnat family
KCKOBFID_01205 4.7e-24 L Transposase
KCKOBFID_01206 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCKOBFID_01207 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KCKOBFID_01208 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCKOBFID_01209 6.6e-122 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KCKOBFID_01210 3.9e-15 M LysM domain
KCKOBFID_01211 2.9e-90 ebsA S Family of unknown function (DUF5322)
KCKOBFID_01212 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KCKOBFID_01213 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCKOBFID_01214 3.7e-224 G COG0457 FOG TPR repeat
KCKOBFID_01215 6.2e-176 yubA S permease
KCKOBFID_01216 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KCKOBFID_01217 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KCKOBFID_01218 2.5e-124 ftsE D cell division ATP-binding protein FtsE
KCKOBFID_01219 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCKOBFID_01220 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCKOBFID_01221 1.1e-180 yjjH S Calcineurin-like phosphoesterase
KCKOBFID_01222 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KCKOBFID_01223 0.0 pacL 3.6.3.8 P cation transport ATPase
KCKOBFID_01224 2.6e-67 ywiB S Domain of unknown function (DUF1934)
KCKOBFID_01225 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
KCKOBFID_01226 1.2e-146 yidA S hydrolases of the HAD superfamily
KCKOBFID_01227 1.8e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KCKOBFID_01228 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KCKOBFID_01229 1.5e-247 vicK 2.7.13.3 T Histidine kinase
KCKOBFID_01230 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCKOBFID_01231 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCKOBFID_01232 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCKOBFID_01233 5.9e-118 gltJ P ABC transporter (Permease
KCKOBFID_01234 1.7e-111 tcyB_2 P ABC transporter (permease)
KCKOBFID_01235 2.4e-124 endA F DNA RNA non-specific endonuclease
KCKOBFID_01236 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
KCKOBFID_01237 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCKOBFID_01239 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCKOBFID_01240 2.2e-21 G Domain of unknown function (DUF4832)
KCKOBFID_01241 8.4e-53 G Domain of unknown function (DUF4832)
KCKOBFID_01242 1.5e-211 cotH M CotH kinase protein
KCKOBFID_01243 2.3e-49 pelG S Putative exopolysaccharide Exporter (EPS-E)
KCKOBFID_01244 3.8e-199 pelG M Putative exopolysaccharide Exporter (EPS-E)
KCKOBFID_01245 4.3e-277 pelF GT4 M Domain of unknown function (DUF3492)
KCKOBFID_01246 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KCKOBFID_01247 2.2e-168
KCKOBFID_01248 0.0 5.1.3.2 GM Psort location CytoplasmicMembrane, score
KCKOBFID_01249 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCKOBFID_01250 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KCKOBFID_01251 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCKOBFID_01252 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KCKOBFID_01253 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCKOBFID_01254 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
KCKOBFID_01257 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KCKOBFID_01258 3.2e-220 XK27_05110 P chloride
KCKOBFID_01259 5.1e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KCKOBFID_01260 6.4e-282 clcA P Chloride transporter, ClC family
KCKOBFID_01261 2.3e-75 fld C Flavodoxin
KCKOBFID_01262 5.5e-14 XK27_08880
KCKOBFID_01263 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
KCKOBFID_01264 9.2e-152 estA CE1 S Putative esterase
KCKOBFID_01265 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCKOBFID_01266 1.2e-135 XK27_08845 S abc transporter atp-binding protein
KCKOBFID_01267 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KCKOBFID_01268 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
KCKOBFID_01269 3.2e-17 S Domain of unknown function (DUF4649)
KCKOBFID_01271 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
KCKOBFID_01272 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
KCKOBFID_01275 1.6e-131 cbiO P ABC transporter
KCKOBFID_01276 1.7e-137 P cobalt transport protein
KCKOBFID_01277 2.7e-177 cbiM P PDGLE domain
KCKOBFID_01278 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KCKOBFID_01279 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KCKOBFID_01280 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KCKOBFID_01281 6.6e-78 ureE O enzyme active site formation
KCKOBFID_01282 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KCKOBFID_01283 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KCKOBFID_01284 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KCKOBFID_01285 6.8e-95 ureI S AmiS/UreI family transporter
KCKOBFID_01286 1.4e-54 S Domain of unknown function (DUF4173)
KCKOBFID_01287 3.7e-22 yhaI L Membrane
KCKOBFID_01288 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCKOBFID_01289 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCKOBFID_01290 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCKOBFID_01291 1.6e-32 V protein secretion by the type I secretion system
KCKOBFID_01292 2.5e-161 K sequence-specific DNA binding
KCKOBFID_01293 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
KCKOBFID_01294 4.3e-109 capA M Bacterial capsule synthesis protein
KCKOBFID_01295 1.5e-55 capA M Bacterial capsule synthesis protein
KCKOBFID_01296 3.6e-39 gcvR T UPF0237 protein
KCKOBFID_01297 1.7e-243 XK27_08635 S UPF0210 protein
KCKOBFID_01298 2.4e-135 ais G Phosphoglycerate mutase
KCKOBFID_01299 2.1e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KCKOBFID_01300 1.3e-102 acmA 3.2.1.17 NU amidase activity
KCKOBFID_01301 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KCKOBFID_01302 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCKOBFID_01303 7.5e-298 dnaK O Heat shock 70 kDa protein
KCKOBFID_01304 3.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KCKOBFID_01305 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KCKOBFID_01306 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KCKOBFID_01307 3.8e-31 hmpT S membrane
KCKOBFID_01308 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KCKOBFID_01309 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KCKOBFID_01310 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KCKOBFID_01311 4.9e-227 pyrP F uracil Permease
KCKOBFID_01312 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KCKOBFID_01313 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCKOBFID_01314 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCKOBFID_01315 1.8e-167 fhuR K transcriptional regulator (lysR family)
KCKOBFID_01320 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KCKOBFID_01321 8.7e-259 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCKOBFID_01322 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KCKOBFID_01323 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCKOBFID_01324 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KCKOBFID_01325 1.4e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KCKOBFID_01326 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KCKOBFID_01327 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KCKOBFID_01328 3.2e-74 copY K Copper transport repressor, CopY TcrY family
KCKOBFID_01329 0.0 copA 3.6.3.54 P P-type ATPase
KCKOBFID_01330 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
KCKOBFID_01331 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCKOBFID_01332 9.4e-43 K Cold-Shock Protein
KCKOBFID_01333 5.4e-32 cspD K Cold shock protein domain
KCKOBFID_01334 5.8e-41 pepD E dipeptidase activity
KCKOBFID_01335 2.8e-90 pepD E Dipeptidase
KCKOBFID_01336 8.7e-162 whiA K May be required for sporulation
KCKOBFID_01337 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KCKOBFID_01338 1.2e-163 rapZ S Displays ATPase and GTPase activities
KCKOBFID_01339 7.4e-138 yejC S cyclic nucleotide-binding protein
KCKOBFID_01340 7.7e-20 D nuclear chromosome segregation
KCKOBFID_01341 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KCKOBFID_01342 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KCKOBFID_01343 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
KCKOBFID_01344 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCKOBFID_01345 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KCKOBFID_01346 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
KCKOBFID_01347 3.1e-268 clcA P Chloride transporter, ClC family
KCKOBFID_01348 8.9e-206 potD P spermidine putrescine ABC transporter
KCKOBFID_01349 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
KCKOBFID_01350 1.5e-118 L Transposase
KCKOBFID_01351 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
KCKOBFID_01352 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KCKOBFID_01354 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
KCKOBFID_01355 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCKOBFID_01356 5.5e-83 S Putative small multi-drug export protein
KCKOBFID_01357 1.8e-75 ctsR K Belongs to the CtsR family
KCKOBFID_01358 0.0 clpC O Belongs to the ClpA ClpB family
KCKOBFID_01359 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCKOBFID_01360 1.7e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCKOBFID_01361 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
KCKOBFID_01362 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
KCKOBFID_01363 5.8e-109 MA20_06410 E LysE type translocator
KCKOBFID_01364 5.6e-08
KCKOBFID_01365 2.7e-09
KCKOBFID_01366 0.0 M family 8
KCKOBFID_01367 7.4e-165 hrtB V MacB-like periplasmic core domain
KCKOBFID_01368 8.3e-117 devA 3.6.3.25 V abc transporter atp-binding protein
KCKOBFID_01369 1.6e-18 L Integrase core domain
KCKOBFID_01370 3e-13 mesE M Transport protein ComB
KCKOBFID_01371 0.0 P Belongs to the ABC transporter superfamily
KCKOBFID_01372 1.8e-141 dppC P N-terminal TM domain of oligopeptide transport permease C
KCKOBFID_01373 2.8e-188 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCKOBFID_01374 0.0 ddpA E ABC transporter substrate-binding protein
KCKOBFID_01376 1.9e-57 L Transposase
KCKOBFID_01377 9.2e-297 adcA P Belongs to the bacterial solute-binding protein 9 family
KCKOBFID_01378 2.2e-101 XK27_10720 D peptidase activity
KCKOBFID_01379 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
KCKOBFID_01380 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
KCKOBFID_01381 3.7e-157 glcU U Glucose uptake
KCKOBFID_01382 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
KCKOBFID_01383 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
KCKOBFID_01385 4.3e-118 S TraX protein
KCKOBFID_01386 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KCKOBFID_01387 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KCKOBFID_01388 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KCKOBFID_01389 6e-188 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCKOBFID_01390 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCKOBFID_01391 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
KCKOBFID_01392 1.1e-204 csm1 S CRISPR-associated protein Csm1 family
KCKOBFID_01393 1.2e-210 csm1 S CRISPR-associated protein Csm1 family
KCKOBFID_01394 2.5e-62 csm2 L Csm2 Type III-A
KCKOBFID_01395 1.6e-117 csm3 L RAMP superfamily
KCKOBFID_01396 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
KCKOBFID_01397 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
KCKOBFID_01399 9.5e-32 csm6 S Psort location Cytoplasmic, score
KCKOBFID_01400 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KCKOBFID_01401 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCKOBFID_01402 1.6e-266 dtpT E transporter
KCKOBFID_01403 1.4e-62 yecS P ABC transporter (Permease
KCKOBFID_01404 2.3e-20 yecS P amino acid transport
KCKOBFID_01406 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KCKOBFID_01407 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
KCKOBFID_01408 4e-99 yfiF3 K sequence-specific DNA binding
KCKOBFID_01409 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KCKOBFID_01410 1.8e-240 agcS E (Alanine) symporter
KCKOBFID_01411 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KCKOBFID_01412 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
KCKOBFID_01413 1.8e-59 Q phosphatase activity
KCKOBFID_01414 9.3e-62 S haloacid dehalogenase-like hydrolase
KCKOBFID_01415 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KCKOBFID_01416 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KCKOBFID_01417 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
KCKOBFID_01418 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
KCKOBFID_01419 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCKOBFID_01420 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KCKOBFID_01421 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KCKOBFID_01422 1.9e-43 yktA S Belongs to the UPF0223 family
KCKOBFID_01423 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KCKOBFID_01424 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KCKOBFID_01425 3.3e-158 pstS P phosphate
KCKOBFID_01426 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KCKOBFID_01427 1.2e-155 pstA P phosphate transport system permease
KCKOBFID_01428 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCKOBFID_01429 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCKOBFID_01430 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
KCKOBFID_01431 0.0 pepN 3.4.11.2 E aminopeptidase
KCKOBFID_01432 8.3e-196 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KCKOBFID_01433 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
KCKOBFID_01436 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KCKOBFID_01437 1.2e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KCKOBFID_01438 2.3e-23 L Transposase
KCKOBFID_01439 4.6e-25 tatA U protein secretion
KCKOBFID_01440 9e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCKOBFID_01441 7.2e-303 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KCKOBFID_01442 8.7e-234 ycdB P peroxidase
KCKOBFID_01443 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
KCKOBFID_01444 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
KCKOBFID_01445 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
KCKOBFID_01446 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCKOBFID_01447 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KCKOBFID_01448 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCKOBFID_01449 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCKOBFID_01450 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCKOBFID_01451 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCKOBFID_01452 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCKOBFID_01453 8.6e-187 3.5.1.28 M GBS Bsp-like repeat
KCKOBFID_01454 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCKOBFID_01455 6.4e-11 3.5.1.28 NU amidase activity
KCKOBFID_01456 0.0 lpdA 1.8.1.4 C Dehydrogenase
KCKOBFID_01457 1.1e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCKOBFID_01458 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KCKOBFID_01459 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KCKOBFID_01460 1.1e-37 P membrane protein (DUF2207)
KCKOBFID_01461 4.4e-66 S the current gene model (or a revised gene model) may contain a frame shift
KCKOBFID_01462 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KCKOBFID_01463 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCKOBFID_01464 3e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCKOBFID_01465 3.8e-17 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
KCKOBFID_01466 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
KCKOBFID_01467 1.3e-125 3.4.16.4 M Belongs to the peptidase S11 family
KCKOBFID_01468 1.3e-159 rssA S Phospholipase, patatin family
KCKOBFID_01469 6.1e-79 estA E GDSL-like protein
KCKOBFID_01470 2.6e-15 estA E Lysophospholipase L1 and related esterases
KCKOBFID_01471 2e-294 S unusual protein kinase
KCKOBFID_01472 4.9e-39 S granule-associated protein
KCKOBFID_01473 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCKOBFID_01474 3.5e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCKOBFID_01475 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCKOBFID_01476 1.3e-199 S hmm pf01594
KCKOBFID_01477 3.9e-61 G Belongs to the phosphoglycerate mutase family
KCKOBFID_01478 3.5e-29 G Belongs to the phosphoglycerate mutase family
KCKOBFID_01479 7.6e-70 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
KCKOBFID_01480 1.4e-96 V VanZ like family
KCKOBFID_01481 1e-110 L Integrase core domain protein
KCKOBFID_01482 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
KCKOBFID_01483 1.4e-40 tatD L Hydrolase, tatd
KCKOBFID_01484 3.8e-45 oppF P Belongs to the ABC transporter superfamily
KCKOBFID_01485 1e-23 oppF P Belongs to the ABC transporter superfamily
KCKOBFID_01486 4.1e-158 L COG2801 Transposase and inactivated derivatives
KCKOBFID_01487 8.1e-45 L Transposase
KCKOBFID_01489 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KCKOBFID_01490 0.0 3.6.3.8 P cation transport ATPase
KCKOBFID_01491 8.5e-142 yxkH G deacetylase
KCKOBFID_01492 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KCKOBFID_01493 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KCKOBFID_01494 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KCKOBFID_01495 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCKOBFID_01496 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KCKOBFID_01497 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCKOBFID_01498 8.2e-28 ytrF V efflux transmembrane transporter activity
KCKOBFID_01499 3.1e-31 V efflux transmembrane transporter activity
KCKOBFID_01500 3.6e-35 V efflux transmembrane transporter activity
KCKOBFID_01501 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
KCKOBFID_01502 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KCKOBFID_01503 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCKOBFID_01504 2.8e-40 T PhoQ Sensor
KCKOBFID_01505 1.7e-43 T PhoQ Sensor
KCKOBFID_01506 5.8e-79 T PhoQ Sensor
KCKOBFID_01513 5.3e-11
KCKOBFID_01519 1.3e-140 mreC M Involved in formation and maintenance of cell shape
KCKOBFID_01520 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KCKOBFID_01521 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KCKOBFID_01522 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KCKOBFID_01523 2.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
KCKOBFID_01524 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KCKOBFID_01525 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KCKOBFID_01526 2.9e-18 yebC M Membrane
KCKOBFID_01527 2.6e-80 yebC M Membrane
KCKOBFID_01528 3.6e-66 KT response to antibiotic
KCKOBFID_01529 5.2e-75 XK27_02470 K LytTr DNA-binding domain
KCKOBFID_01530 2.6e-121 liaI S membrane
KCKOBFID_01531 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KCKOBFID_01532 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KCKOBFID_01533 1.6e-11 S Protein of unknown function (DUF554)
KCKOBFID_01534 8.5e-32 S Protein of unknown function (DUF554)
KCKOBFID_01535 2.5e-47 S Protein of unknown function (DUF554)
KCKOBFID_01536 1.4e-133 ecsA_2 V abc transporter atp-binding protein
KCKOBFID_01537 6.2e-288 XK27_00765
KCKOBFID_01538 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCKOBFID_01539 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCKOBFID_01540 1.3e-08 D nuclear chromosome segregation
KCKOBFID_01541 9.7e-32 yhaI J Protein of unknown function (DUF805)
KCKOBFID_01543 2.6e-30
KCKOBFID_01544 7.4e-27
KCKOBFID_01545 1.6e-65
KCKOBFID_01546 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KCKOBFID_01547 4.3e-47 ftsL D cell division protein FtsL
KCKOBFID_01548 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KCKOBFID_01549 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCKOBFID_01550 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KCKOBFID_01552 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KCKOBFID_01553 3.6e-70 yutD J protein conserved in bacteria
KCKOBFID_01554 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KCKOBFID_01555 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KCKOBFID_01557 9.1e-303 mdlA V abc transporter atp-binding protein
KCKOBFID_01558 0.0 mdlB V abc transporter atp-binding protein
KCKOBFID_01559 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCKOBFID_01560 7.3e-237 mesE M Transport protein ComB
KCKOBFID_01562 3.4e-239 blpH 2.7.13.3 T protein histidine kinase activity
KCKOBFID_01563 7.4e-135 agrA KT phosphorelay signal transduction system
KCKOBFID_01567 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
KCKOBFID_01574 6.7e-98 blpT
KCKOBFID_01575 2.9e-28 blpT
KCKOBFID_01576 3e-47 spiA K sequence-specific DNA binding
KCKOBFID_01579 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KCKOBFID_01580 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KCKOBFID_01581 5e-44 V CAAX protease self-immunity
KCKOBFID_01582 4.6e-140 cppA E CppA N-terminal
KCKOBFID_01583 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KCKOBFID_01584 1.2e-117 ybbL S abc transporter atp-binding protein
KCKOBFID_01585 1.5e-127 ybbM S transport system, permease component
KCKOBFID_01586 2.9e-87 D nuclear chromosome segregation
KCKOBFID_01587 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
KCKOBFID_01588 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCKOBFID_01589 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
KCKOBFID_01590 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KCKOBFID_01591 1.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCKOBFID_01593 1.2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCKOBFID_01594 4.7e-163 yxeN P ABC transporter (Permease
KCKOBFID_01595 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
KCKOBFID_01596 1.9e-09 S Protein of unknown function (DUF4059)
KCKOBFID_01597 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KCKOBFID_01598 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
KCKOBFID_01599 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCKOBFID_01600 2.2e-196 ylbL T Belongs to the peptidase S16 family
KCKOBFID_01601 1.3e-184 yhcC S radical SAM protein
KCKOBFID_01602 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
KCKOBFID_01604 0.0 yjcE P NhaP-type Na H and K H antiporters
KCKOBFID_01605 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KCKOBFID_01606 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KCKOBFID_01608 9.8e-71 L Phage integrase family
KCKOBFID_01609 2.4e-23 S phage tail tape measure protein
KCKOBFID_01610 7.1e-130 S EcsC protein family
KCKOBFID_01611 2e-20 S phage tail
KCKOBFID_01612 8.4e-66 tnp L Transposase IS66 family
KCKOBFID_01613 1.9e-225 nodC 2.4.1.212 GT2 M Chitin synthase
KCKOBFID_01614 2.4e-214 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KCKOBFID_01615 0.0 copB 3.6.3.4 P P-type ATPase
KCKOBFID_01616 1.4e-92 3.6.4.12 K Divergent AAA domain protein
KCKOBFID_01617 5.9e-24 3.6.4.12
KCKOBFID_01618 7.7e-112 EGP Major facilitator Superfamily
KCKOBFID_01619 4.7e-56 EGP Major facilitator Superfamily
KCKOBFID_01620 3e-246 cps1C S Polysaccharide biosynthesis protein
KCKOBFID_01621 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KCKOBFID_01622 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
KCKOBFID_01623 3.1e-10 L thioesterase
KCKOBFID_01624 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
KCKOBFID_01625 2.8e-93 pat 2.3.1.183 M acetyltransferase
KCKOBFID_01626 7.3e-82 alkD L Dna alkylation repair
KCKOBFID_01627 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCKOBFID_01628 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCKOBFID_01629 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KCKOBFID_01630 0.0 smc D Required for chromosome condensation and partitioning
KCKOBFID_01631 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCKOBFID_01632 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCKOBFID_01633 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCKOBFID_01635 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KCKOBFID_01636 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KCKOBFID_01638 2e-86 S ECF-type riboflavin transporter, S component
KCKOBFID_01639 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KCKOBFID_01640 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KCKOBFID_01641 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
KCKOBFID_01642 1.9e-294 yfmM S abc transporter atp-binding protein
KCKOBFID_01643 3.4e-258 noxE P NADH oxidase
KCKOBFID_01644 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KCKOBFID_01645 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCKOBFID_01646 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KCKOBFID_01647 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
KCKOBFID_01648 1.8e-165 ypuA S secreted protein
KCKOBFID_01649 3.3e-26 L Transposase (IS116 IS110 IS902 family)
KCKOBFID_01650 4.2e-71 L Transposase (IS116 IS110 IS902 family)
KCKOBFID_01652 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCKOBFID_01653 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCKOBFID_01654 2.2e-34 nrdH O Glutaredoxin
KCKOBFID_01655 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCKOBFID_01656 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
KCKOBFID_01657 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
KCKOBFID_01658 7.9e-39 ptsH G phosphocarrier protein Hpr
KCKOBFID_01659 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCKOBFID_01660 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KCKOBFID_01661 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCKOBFID_01662 9.3e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
KCKOBFID_01663 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KCKOBFID_01664 0.0 uup S abc transporter atp-binding protein
KCKOBFID_01665 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
KCKOBFID_01666 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCKOBFID_01667 8.7e-150 cobQ S glutamine amidotransferase
KCKOBFID_01668 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KCKOBFID_01669 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCKOBFID_01670 6e-169 ybbR S Protein conserved in bacteria
KCKOBFID_01671 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCKOBFID_01672 1.7e-70 gtrA S GtrA-like protein
KCKOBFID_01673 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KCKOBFID_01674 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KCKOBFID_01675 2.3e-14 zupT P Mediates zinc uptake. May also transport other divalent cations
KCKOBFID_01676 6.4e-29 zupT P transporter
KCKOBFID_01677 1.6e-207 yurR 1.4.5.1 E oxidoreductase
KCKOBFID_01678 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCKOBFID_01679 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCKOBFID_01680 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KCKOBFID_01683 1.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KCKOBFID_01684 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
KCKOBFID_01685 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KCKOBFID_01686 1.1e-121 ylfI S tigr01906
KCKOBFID_01687 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KCKOBFID_01688 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KCKOBFID_01689 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KCKOBFID_01690 1.3e-22 XK27_08085
KCKOBFID_01692 3.7e-27 S Membrane
KCKOBFID_01693 1.2e-67 L transposase activity
KCKOBFID_01694 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KCKOBFID_01695 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCKOBFID_01696 5.2e-142 cmpC S abc transporter atp-binding protein
KCKOBFID_01697 0.0 WQ51_06230 S ABC transporter substrate binding protein
KCKOBFID_01698 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KCKOBFID_01699 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KCKOBFID_01700 1.3e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KCKOBFID_01701 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCKOBFID_01702 9.8e-50 yajC U protein transport
KCKOBFID_01703 1.9e-127 yeeN K transcriptional regulatory protein
KCKOBFID_01704 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
KCKOBFID_01705 1e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
KCKOBFID_01706 1.7e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KCKOBFID_01707 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
KCKOBFID_01708 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KCKOBFID_01709 4.8e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KCKOBFID_01710 5.4e-131 adcB P ABC transporter (Permease
KCKOBFID_01711 2.2e-136 adcC P ABC transporter, ATP-binding protein
KCKOBFID_01712 3.1e-72 adcR K transcriptional
KCKOBFID_01713 1.9e-209 EGP Major facilitator Superfamily
KCKOBFID_01714 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCKOBFID_01715 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCKOBFID_01718 9e-170 oppF P Belongs to the ABC transporter superfamily
KCKOBFID_01719 1.3e-44 oppD P Belongs to the ABC transporter superfamily
KCKOBFID_01720 4.8e-67 oppD P Belongs to the ABC transporter superfamily
KCKOBFID_01721 2.5e-32 oppD P Belongs to the ABC transporter superfamily
KCKOBFID_01722 8e-28 oppD P Belongs to the ABC transporter superfamily
KCKOBFID_01723 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCKOBFID_01724 5.4e-46 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCKOBFID_01725 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCKOBFID_01726 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCKOBFID_01727 5.4e-99 oppA E ABC transporter substrate-binding protein
KCKOBFID_01728 2.4e-19 oppA E ABC transporter substrate-binding protein
KCKOBFID_01729 3.5e-274 sufB O assembly protein SufB
KCKOBFID_01730 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
KCKOBFID_01731 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCKOBFID_01732 6.3e-235 sufD O assembly protein SufD
KCKOBFID_01733 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KCKOBFID_01734 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
KCKOBFID_01735 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KCKOBFID_01736 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KCKOBFID_01737 1.8e-276 glnP P ABC transporter
KCKOBFID_01738 1e-123 glnQ E abc transporter atp-binding protein
KCKOBFID_01741 5e-94 V VanZ like family
KCKOBFID_01742 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCKOBFID_01743 6.5e-202 yhjX P Major Facilitator
KCKOBFID_01744 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KCKOBFID_01745 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KCKOBFID_01746 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCKOBFID_01747 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCKOBFID_01748 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCKOBFID_01749 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCKOBFID_01750 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCKOBFID_01751 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KCKOBFID_01752 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCKOBFID_01753 2.4e-83 nrdI F Belongs to the NrdI family
KCKOBFID_01754 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KCKOBFID_01755 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KCKOBFID_01756 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
KCKOBFID_01757 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KCKOBFID_01758 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
KCKOBFID_01759 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KCKOBFID_01760 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KCKOBFID_01761 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KCKOBFID_01762 3e-148 ykuT M mechanosensitive ion channel
KCKOBFID_01763 1.6e-77 sigH K DNA-templated transcription, initiation
KCKOBFID_01764 4.4e-83
KCKOBFID_01765 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KCKOBFID_01766 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KCKOBFID_01767 6.5e-50 M YSIRK type signal peptide
KCKOBFID_01768 3e-92 S MucBP domain
KCKOBFID_01769 1.1e-151 V MatE
KCKOBFID_01771 1.5e-109 C Fe-S oxidoreductases
KCKOBFID_01772 1.2e-176 EGP Major Facilitator Superfamily
KCKOBFID_01773 5.5e-258 I radical SAM domain protein
KCKOBFID_01775 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCKOBFID_01776 1.4e-150 L Integrase core domain protein
KCKOBFID_01777 1.8e-87 L transposase activity
KCKOBFID_01779 1.5e-61
KCKOBFID_01780 0.0 sbcC L ATPase involved in DNA repair
KCKOBFID_01781 5.3e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KCKOBFID_01782 0.0 lacL 3.2.1.23 G -beta-galactosidase
KCKOBFID_01783 0.0 lacS G transporter
KCKOBFID_01784 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KCKOBFID_01785 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCKOBFID_01786 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KCKOBFID_01787 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCKOBFID_01788 1.8e-184 galR K Transcriptional regulator
KCKOBFID_01789 2.7e-08 L Integrase core domain protein
KCKOBFID_01790 1.2e-25 L transposition
KCKOBFID_01791 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KCKOBFID_01792 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KCKOBFID_01793 2.5e-101 V abc transporter atp-binding protein
KCKOBFID_01794 4.3e-40 V abc transporter atp-binding protein
KCKOBFID_01795 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KCKOBFID_01796 2.3e-87 L Transposase
KCKOBFID_01797 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KCKOBFID_01798 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KCKOBFID_01799 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KCKOBFID_01800 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCKOBFID_01803 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCKOBFID_01804 5.8e-175 vraS 2.7.13.3 T Histidine kinase
KCKOBFID_01805 3.7e-120 yvqF KT membrane
KCKOBFID_01806 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KCKOBFID_01807 9e-133 stp 3.1.3.16 T phosphatase
KCKOBFID_01808 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCKOBFID_01809 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCKOBFID_01810 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCKOBFID_01811 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KCKOBFID_01812 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KCKOBFID_01813 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KCKOBFID_01814 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
KCKOBFID_01815 2.1e-148 supH S overlaps another CDS with the same product name
KCKOBFID_01816 8.6e-63 yvoA_1 K Transcriptional
KCKOBFID_01817 9.8e-121 skfE V abc transporter atp-binding protein
KCKOBFID_01818 5.6e-133 V ATPase activity
KCKOBFID_01819 4.3e-172 oppF P Belongs to the ABC transporter superfamily
KCKOBFID_01820 2.2e-204 oppD P Belongs to the ABC transporter superfamily
KCKOBFID_01821 4.9e-168 amiD P ABC transporter (Permease
KCKOBFID_01822 4.2e-278 amiC P ABC transporter (Permease
KCKOBFID_01823 6.3e-293 amiA E ABC transporter, substrate-binding protein, family 5
KCKOBFID_01824 1.1e-29 yyzM S Protein conserved in bacteria
KCKOBFID_01825 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KCKOBFID_01826 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KCKOBFID_01827 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCKOBFID_01828 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KCKOBFID_01829 2.7e-61 divIC D Septum formation initiator
KCKOBFID_01831 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KCKOBFID_01832 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KCKOBFID_01833 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KCKOBFID_01834 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCKOBFID_01835 2.4e-164 L Transposase
KCKOBFID_01836 2.8e-36 L Transposase
KCKOBFID_01837 6.4e-18 L transposase activity
KCKOBFID_01840 4.7e-43
KCKOBFID_01841 6.8e-56 S TM2 domain
KCKOBFID_01842 7.3e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCKOBFID_01843 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCKOBFID_01844 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
KCKOBFID_01845 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KCKOBFID_01846 1.2e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KCKOBFID_01847 6e-55 cof Q phosphatase activity
KCKOBFID_01848 4e-34 cof Q phosphatase activity
KCKOBFID_01849 2.8e-76 glcR K transcriptional regulator (DeoR family)
KCKOBFID_01850 3.9e-21 glcR K transcriptional regulator (DeoR family)
KCKOBFID_01851 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCKOBFID_01852 3.8e-40 K transcriptional
KCKOBFID_01854 2.6e-76 S thiolester hydrolase activity
KCKOBFID_01855 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
KCKOBFID_01856 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCKOBFID_01857 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KCKOBFID_01858 1.9e-77 yhaI L Membrane
KCKOBFID_01859 4.6e-260 pepC 3.4.22.40 E aminopeptidase
KCKOBFID_01860 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCKOBFID_01861 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KCKOBFID_01862 3.1e-95 ypsA S Belongs to the UPF0398 family
KCKOBFID_01863 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KCKOBFID_01864 7.9e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KCKOBFID_01865 1e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KCKOBFID_01866 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KCKOBFID_01867 2.5e-23
KCKOBFID_01868 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KCKOBFID_01869 3.1e-20 XK27_09675 K -acetyltransferase
KCKOBFID_01870 9.3e-46 XK27_09675 K -acetyltransferase
KCKOBFID_01871 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCKOBFID_01872 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KCKOBFID_01873 2.9e-87 L Integrase core domain protein
KCKOBFID_01874 3.5e-97 S reductase
KCKOBFID_01875 2.6e-55 badR K DNA-binding transcription factor activity
KCKOBFID_01876 1.9e-36 XK27_02060 S Transglycosylase associated protein
KCKOBFID_01877 2.3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KCKOBFID_01878 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCKOBFID_01884 4.8e-16 S Protein of unknown function (DUF2969)
KCKOBFID_01885 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KCKOBFID_01886 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCKOBFID_01887 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCKOBFID_01888 1.2e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)