ORF_ID e_value Gene_name EC_number CAZy COGs Description
LLMDOFAF_00001 1.6e-77 sigH K DNA-templated transcription, initiation
LLMDOFAF_00002 3e-148 ykuT M mechanosensitive ion channel
LLMDOFAF_00003 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
LLMDOFAF_00004 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
LLMDOFAF_00005 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
LLMDOFAF_00006 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
LLMDOFAF_00007 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
LLMDOFAF_00008 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
LLMDOFAF_00009 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
LLMDOFAF_00010 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
LLMDOFAF_00011 2.4e-83 nrdI F Belongs to the NrdI family
LLMDOFAF_00012 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LLMDOFAF_00013 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
LLMDOFAF_00014 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LLMDOFAF_00015 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LLMDOFAF_00016 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LLMDOFAF_00017 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
LLMDOFAF_00018 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LLMDOFAF_00019 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
LLMDOFAF_00020 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
LLMDOFAF_00021 6.5e-202 yhjX P Major Facilitator
LLMDOFAF_00022 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LLMDOFAF_00023 5e-94 V VanZ like family
LLMDOFAF_00026 1e-123 glnQ E abc transporter atp-binding protein
LLMDOFAF_00027 1.8e-276 glnP P ABC transporter
LLMDOFAF_00028 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
LLMDOFAF_00029 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
LLMDOFAF_00030 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
LLMDOFAF_00031 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
LLMDOFAF_00032 6.3e-235 sufD O assembly protein SufD
LLMDOFAF_00033 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LLMDOFAF_00034 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
LLMDOFAF_00035 3.5e-274 sufB O assembly protein SufB
LLMDOFAF_00036 2.4e-19 oppA E ABC transporter substrate-binding protein
LLMDOFAF_00037 5.4e-99 oppA E ABC transporter substrate-binding protein
LLMDOFAF_00038 2.7e-17 oppA E ABC transporter substrate-binding protein
LLMDOFAF_00039 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLMDOFAF_00040 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLMDOFAF_00041 5.4e-46 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLMDOFAF_00042 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLMDOFAF_00043 8e-28 oppD P Belongs to the ABC transporter superfamily
LLMDOFAF_00044 2.5e-32 oppD P Belongs to the ABC transporter superfamily
LLMDOFAF_00045 4.8e-67 oppD P Belongs to the ABC transporter superfamily
LLMDOFAF_00046 1.3e-44 oppD P Belongs to the ABC transporter superfamily
LLMDOFAF_00047 9e-170 oppF P Belongs to the ABC transporter superfamily
LLMDOFAF_00050 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LLMDOFAF_00051 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LLMDOFAF_00052 1.9e-209 EGP Major facilitator Superfamily
LLMDOFAF_00053 3.1e-72 adcR K transcriptional
LLMDOFAF_00054 2.2e-136 adcC P ABC transporter, ATP-binding protein
LLMDOFAF_00055 5.4e-131 adcB P ABC transporter (Permease
LLMDOFAF_00056 4.8e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
LLMDOFAF_00057 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
LLMDOFAF_00058 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
LLMDOFAF_00059 1.7e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
LLMDOFAF_00060 1e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
LLMDOFAF_00061 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
LLMDOFAF_00062 1.9e-127 yeeN K transcriptional regulatory protein
LLMDOFAF_00063 9.8e-50 yajC U protein transport
LLMDOFAF_00064 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LLMDOFAF_00065 1.3e-145 cdsA 2.7.7.41 S Belongs to the CDS family
LLMDOFAF_00066 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
LLMDOFAF_00067 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
LLMDOFAF_00068 0.0 WQ51_06230 S ABC transporter substrate binding protein
LLMDOFAF_00069 5.2e-142 cmpC S abc transporter atp-binding protein
LLMDOFAF_00070 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LLMDOFAF_00071 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
LLMDOFAF_00072 4.4e-37 L Transposase
LLMDOFAF_00073 6.4e-18 L transposase activity
LLMDOFAF_00074 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
LLMDOFAF_00075 1e-33 L Transposase
LLMDOFAF_00076 1e-13 rpmH J Ribosomal protein L34
LLMDOFAF_00077 2e-186 jag S RNA-binding protein
LLMDOFAF_00078 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LLMDOFAF_00079 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
LLMDOFAF_00080 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
LLMDOFAF_00081 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
LLMDOFAF_00082 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LLMDOFAF_00083 6.7e-81 amiA E transmembrane transport
LLMDOFAF_00084 2e-41 amiA E transmembrane transport
LLMDOFAF_00085 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
LLMDOFAF_00086 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
LLMDOFAF_00087 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
LLMDOFAF_00088 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LLMDOFAF_00089 9.2e-51 S Protein of unknown function (DUF3397)
LLMDOFAF_00090 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
LLMDOFAF_00091 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
LLMDOFAF_00092 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
LLMDOFAF_00093 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
LLMDOFAF_00094 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LLMDOFAF_00095 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
LLMDOFAF_00096 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
LLMDOFAF_00097 4.3e-77 XK27_09620 S reductase
LLMDOFAF_00098 9e-62 XK27_09615 C reductase
LLMDOFAF_00099 1e-141 XK27_09615 C reductase
LLMDOFAF_00100 3.2e-62 fnt P Formate nitrite transporter
LLMDOFAF_00101 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
LLMDOFAF_00102 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
LLMDOFAF_00103 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
LLMDOFAF_00104 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
LLMDOFAF_00105 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LLMDOFAF_00106 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
LLMDOFAF_00107 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
LLMDOFAF_00108 2.7e-48 S glycolate biosynthetic process
LLMDOFAF_00109 1.5e-64 S phosphatase activity
LLMDOFAF_00110 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
LLMDOFAF_00113 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
LLMDOFAF_00114 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LLMDOFAF_00115 8.3e-37 yeeD O sulfur carrier activity
LLMDOFAF_00116 2.8e-193 yeeE S Sulphur transport
LLMDOFAF_00117 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LLMDOFAF_00118 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
LLMDOFAF_00119 4.1e-09 S Domain of unknown function (DUF4651)
LLMDOFAF_00120 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
LLMDOFAF_00121 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LLMDOFAF_00122 1.8e-111 S CAAX amino terminal protease family protein
LLMDOFAF_00124 5e-67 V CAAX protease self-immunity
LLMDOFAF_00125 1.4e-33 V CAAX protease self-immunity
LLMDOFAF_00126 8.8e-27 lanR K sequence-specific DNA binding
LLMDOFAF_00127 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LLMDOFAF_00128 5.9e-177 ytxK 2.1.1.72 L DNA methylase
LLMDOFAF_00129 2e-12 comGF U Putative Competence protein ComGF
LLMDOFAF_00130 1.5e-71 comGF U Competence protein ComGF
LLMDOFAF_00131 1.4e-15 NU Type II secretory pathway pseudopilin
LLMDOFAF_00132 1.8e-57 cglD NU Competence protein
LLMDOFAF_00133 8.5e-43 comGC U Required for transformation and DNA binding
LLMDOFAF_00134 1.1e-156 cglB U protein transport across the cell outer membrane
LLMDOFAF_00135 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LLMDOFAF_00136 1e-68 S cog cog4699
LLMDOFAF_00137 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LLMDOFAF_00138 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LLMDOFAF_00139 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LLMDOFAF_00140 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LLMDOFAF_00141 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LLMDOFAF_00142 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
LLMDOFAF_00143 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
LLMDOFAF_00144 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LLMDOFAF_00145 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
LLMDOFAF_00146 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LLMDOFAF_00147 1e-134 parB K Belongs to the ParB family
LLMDOFAF_00148 5.6e-185 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
LLMDOFAF_00149 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LLMDOFAF_00150 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
LLMDOFAF_00154 0.0 XK27_10405 S Bacterial membrane protein YfhO
LLMDOFAF_00155 6.7e-306 ybiT S abc transporter atp-binding protein
LLMDOFAF_00156 1.1e-153 yvjA S membrane
LLMDOFAF_00157 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
LLMDOFAF_00158 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
LLMDOFAF_00159 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LLMDOFAF_00160 1.6e-45 yaaA S S4 domain protein YaaA
LLMDOFAF_00161 4.8e-235 ymfF S Peptidase M16
LLMDOFAF_00162 1.1e-242 ymfH S Peptidase M16
LLMDOFAF_00163 3.7e-138 ymfM S sequence-specific DNA binding
LLMDOFAF_00164 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LLMDOFAF_00165 7.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LLMDOFAF_00166 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LLMDOFAF_00167 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LLMDOFAF_00168 3.1e-93 lytE M LysM domain protein
LLMDOFAF_00169 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
LLMDOFAF_00170 0.0 S Bacterial membrane protein, YfhO
LLMDOFAF_00171 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
LLMDOFAF_00172 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
LLMDOFAF_00173 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
LLMDOFAF_00174 3.9e-70 rplI J binds to the 23S rRNA
LLMDOFAF_00175 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
LLMDOFAF_00176 8.2e-48 veg S Biofilm formation stimulator VEG
LLMDOFAF_00177 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LLMDOFAF_00178 2.7e-08
LLMDOFAF_00179 4.8e-55 ypaA M Membrane
LLMDOFAF_00180 6.4e-96 XK27_06935 K transcriptional regulator
LLMDOFAF_00181 3.9e-161 XK27_06930 V domain protein
LLMDOFAF_00182 1.8e-88 S Putative adhesin
LLMDOFAF_00183 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
LLMDOFAF_00185 1.7e-23 K negative regulation of transcription, DNA-templated
LLMDOFAF_00186 4e-19 K negative regulation of transcription, DNA-templated
LLMDOFAF_00187 3.4e-13 nudL L hydrolase
LLMDOFAF_00188 7.2e-95 nudL L hydrolase
LLMDOFAF_00189 4.9e-12 K CsbD-like
LLMDOFAF_00190 1.1e-71 M Protein conserved in bacteria
LLMDOFAF_00191 1.8e-23 S Small integral membrane protein
LLMDOFAF_00192 3.1e-101
LLMDOFAF_00193 3.7e-27 S Membrane
LLMDOFAF_00195 2.7e-95 S Hydrophobic domain protein
LLMDOFAF_00196 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
LLMDOFAF_00198 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
LLMDOFAF_00199 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
LLMDOFAF_00200 9.2e-36 metE 2.1.1.14 E Methionine synthase
LLMDOFAF_00201 7.6e-64 metE 2.1.1.14 E Methionine synthase
LLMDOFAF_00202 5.7e-52 metE 2.1.1.14 E Methionine synthase
LLMDOFAF_00203 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
LLMDOFAF_00205 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
LLMDOFAF_00206 9.9e-169 XK27_01785 S cog cog1284
LLMDOFAF_00207 1.8e-147 yaaA S Belongs to the UPF0246 family
LLMDOFAF_00208 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LLMDOFAF_00209 2.6e-91 XK27_10930 K acetyltransferase
LLMDOFAF_00210 7.5e-14
LLMDOFAF_00211 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
LLMDOFAF_00212 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
LLMDOFAF_00213 1.3e-87 S Fusaric acid resistance protein-like
LLMDOFAF_00214 8.5e-63 glnR K Transcriptional regulator
LLMDOFAF_00215 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
LLMDOFAF_00216 2.7e-40 pscB M CHAP domain protein
LLMDOFAF_00217 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LLMDOFAF_00218 2.5e-33 ykzG S Belongs to the UPF0356 family
LLMDOFAF_00219 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
LLMDOFAF_00220 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
LLMDOFAF_00221 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LLMDOFAF_00222 1.3e-117 azlC E AzlC protein
LLMDOFAF_00223 2e-47 azlD E branched-chain amino acid
LLMDOFAF_00224 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
LLMDOFAF_00225 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LLMDOFAF_00226 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LLMDOFAF_00227 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LLMDOFAF_00228 1e-93 cvpA S toxin biosynthetic process
LLMDOFAF_00229 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
LLMDOFAF_00230 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LLMDOFAF_00236 2.5e-230 mutY L A G-specific adenine glycosylase
LLMDOFAF_00237 3.6e-41 XK27_05745
LLMDOFAF_00238 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
LLMDOFAF_00239 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
LLMDOFAF_00240 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LLMDOFAF_00242 3.1e-124 XK27_01040 S Pfam PF06570
LLMDOFAF_00243 2e-169 corA P COG0598 Mg2 and Co2 transporters
LLMDOFAF_00244 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LLMDOFAF_00247 3.8e-58 V 'abc transporter, ATP-binding protein
LLMDOFAF_00248 8e-44 V 'abc transporter, ATP-binding protein
LLMDOFAF_00250 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
LLMDOFAF_00251 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
LLMDOFAF_00252 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LLMDOFAF_00253 3.4e-62 yqhY S protein conserved in bacteria
LLMDOFAF_00254 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LLMDOFAF_00255 7.5e-180 scrR K Transcriptional
LLMDOFAF_00256 5.4e-291 scrB 3.2.1.26 GH32 G invertase
LLMDOFAF_00257 0.0 scrA 2.7.1.211 G pts system
LLMDOFAF_00258 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
LLMDOFAF_00259 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
LLMDOFAF_00261 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
LLMDOFAF_00262 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLMDOFAF_00263 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LLMDOFAF_00264 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
LLMDOFAF_00265 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LLMDOFAF_00266 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LLMDOFAF_00268 2.1e-185 V Abi-like protein
LLMDOFAF_00271 2.9e-31 yozG K Transcriptional regulator
LLMDOFAF_00272 9.2e-284 V ABC transporter transmembrane region
LLMDOFAF_00273 1.9e-158 K Helix-turn-helix XRE-family like proteins
LLMDOFAF_00274 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
LLMDOFAF_00275 1.4e-29 S Domain of unknown function (DUF1912)
LLMDOFAF_00276 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
LLMDOFAF_00277 5.2e-251 mmuP E amino acid
LLMDOFAF_00278 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
LLMDOFAF_00279 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LLMDOFAF_00280 9.7e-22
LLMDOFAF_00281 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LLMDOFAF_00282 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LLMDOFAF_00283 1.7e-218 mvaS 2.3.3.10 I synthase
LLMDOFAF_00284 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
LLMDOFAF_00285 1e-25 K hmm pf08876
LLMDOFAF_00286 1.5e-118 yqfA K protein, Hemolysin III
LLMDOFAF_00287 1.2e-22 S Protein of unknown function (DUF3114)
LLMDOFAF_00288 8.6e-167 S Protein of unknown function (DUF3114)
LLMDOFAF_00289 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
LLMDOFAF_00290 8.9e-57 S hydrolase activity, acting on ester bonds
LLMDOFAF_00291 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LLMDOFAF_00292 4.9e-21 XK27_13030
LLMDOFAF_00293 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
LLMDOFAF_00294 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
LLMDOFAF_00296 2.1e-50 U protein secretion
LLMDOFAF_00297 3.5e-07 U protein secretion
LLMDOFAF_00299 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LLMDOFAF_00300 2.5e-21
LLMDOFAF_00301 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
LLMDOFAF_00302 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LLMDOFAF_00303 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
LLMDOFAF_00304 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
LLMDOFAF_00305 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
LLMDOFAF_00306 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
LLMDOFAF_00307 4.6e-105 GBS0088 J protein conserved in bacteria
LLMDOFAF_00308 6.1e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLMDOFAF_00309 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
LLMDOFAF_00310 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
LLMDOFAF_00311 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LLMDOFAF_00312 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LLMDOFAF_00313 8.7e-114 S VIT family
LLMDOFAF_00314 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
LLMDOFAF_00315 1.1e-22
LLMDOFAF_00316 8e-28 XK27_00085 K Transcriptional
LLMDOFAF_00317 2.4e-197 yceA S Belongs to the UPF0176 family
LLMDOFAF_00318 5.4e-122 sagI S ABC-2 type transporter
LLMDOFAF_00319 2.8e-168 V ABC transporter
LLMDOFAF_00320 7.1e-214 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
LLMDOFAF_00321 2.5e-132 rr02 KT response regulator
LLMDOFAF_00322 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
LLMDOFAF_00323 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
LLMDOFAF_00324 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LLMDOFAF_00325 0.0 lmrA V abc transporter atp-binding protein
LLMDOFAF_00326 0.0 mdlB V abc transporter atp-binding protein
LLMDOFAF_00328 0.0 M the current gene model (or a revised gene model) may contain a
LLMDOFAF_00329 6.5e-50 M YSIRK type signal peptide
LLMDOFAF_00330 3e-92 S MucBP domain
LLMDOFAF_00333 1.9e-13
LLMDOFAF_00334 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
LLMDOFAF_00335 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
LLMDOFAF_00336 6.6e-61 EGP Major facilitator Superfamily
LLMDOFAF_00337 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
LLMDOFAF_00338 1.3e-212 pqqE C radical SAM domain protein
LLMDOFAF_00341 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LLMDOFAF_00342 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
LLMDOFAF_00343 3.9e-19 IQ Acetoin reductase
LLMDOFAF_00344 1.8e-51 IQ Acetoin reductase
LLMDOFAF_00345 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLMDOFAF_00346 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
LLMDOFAF_00347 1.1e-152 XK27_05470 E Methionine synthase
LLMDOFAF_00348 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LLMDOFAF_00349 1.3e-249 T PhoQ Sensor
LLMDOFAF_00350 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LLMDOFAF_00351 3.6e-154 S TraX protein
LLMDOFAF_00352 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LLMDOFAF_00353 8.3e-159 dprA LU DNA protecting protein DprA
LLMDOFAF_00354 8.2e-168 GK ROK family
LLMDOFAF_00355 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LLMDOFAF_00356 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LLMDOFAF_00357 9.6e-129 K DNA-binding helix-turn-helix protein
LLMDOFAF_00358 6e-91 niaR S small molecule binding protein (contains 3H domain)
LLMDOFAF_00359 2.4e-87 niaX
LLMDOFAF_00360 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LLMDOFAF_00361 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LLMDOFAF_00362 2e-126 gntR1 K transcriptional
LLMDOFAF_00363 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
LLMDOFAF_00364 1.1e-19 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
LLMDOFAF_00365 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
LLMDOFAF_00366 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
LLMDOFAF_00367 2.1e-07
LLMDOFAF_00368 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLMDOFAF_00369 1.1e-158 aatB ET ABC transporter substrate-binding protein
LLMDOFAF_00370 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
LLMDOFAF_00371 2.4e-105 artQ P ABC transporter (Permease
LLMDOFAF_00372 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
LLMDOFAF_00373 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
LLMDOFAF_00374 2.6e-166 cpsY K Transcriptional regulator
LLMDOFAF_00375 3.2e-35 L transposase activity
LLMDOFAF_00376 5.1e-117 mur1 NU muramidase
LLMDOFAF_00377 1.2e-172 yeiH S Membrane
LLMDOFAF_00379 1.7e-08
LLMDOFAF_00380 9.2e-297 adcA P Belongs to the bacterial solute-binding protein 9 family
LLMDOFAF_00381 2.2e-101 XK27_10720 D peptidase activity
LLMDOFAF_00382 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
LLMDOFAF_00383 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
LLMDOFAF_00384 3.7e-157 glcU U Glucose uptake
LLMDOFAF_00385 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
LLMDOFAF_00386 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
LLMDOFAF_00387 3.7e-44 L Transposase
LLMDOFAF_00388 0.0 yfmR S abc transporter atp-binding protein
LLMDOFAF_00389 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
LLMDOFAF_00390 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
LLMDOFAF_00391 3.6e-74 XK27_08360 S EDD domain protein, DegV family
LLMDOFAF_00392 6.4e-61 XK27_08360 S EDD domain protein, DegV family
LLMDOFAF_00393 2.6e-64 WQ51_03320 S cog cog4835
LLMDOFAF_00394 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLMDOFAF_00395 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
LLMDOFAF_00396 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
LLMDOFAF_00397 6.4e-29 2.3.1.128 K acetyltransferase
LLMDOFAF_00398 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
LLMDOFAF_00399 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
LLMDOFAF_00400 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LLMDOFAF_00401 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
LLMDOFAF_00403 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LLMDOFAF_00404 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LLMDOFAF_00405 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
LLMDOFAF_00406 5.1e-145 fruA 2.7.1.202 G phosphotransferase system
LLMDOFAF_00407 8e-98 fruA 2.7.1.202 G phosphotransferase system
LLMDOFAF_00408 2.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
LLMDOFAF_00409 5.6e-114 fruR K transcriptional
LLMDOFAF_00410 1.8e-84 L Transposase
LLMDOFAF_00411 1.1e-202 rny D Endoribonuclease that initiates mRNA decay
LLMDOFAF_00412 1.4e-65 tnp L Transposase
LLMDOFAF_00413 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
LLMDOFAF_00414 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
LLMDOFAF_00415 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LLMDOFAF_00416 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
LLMDOFAF_00417 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
LLMDOFAF_00418 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
LLMDOFAF_00419 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
LLMDOFAF_00420 1.6e-126 IQ reductase
LLMDOFAF_00421 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
LLMDOFAF_00422 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
LLMDOFAF_00423 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLMDOFAF_00424 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LLMDOFAF_00425 4e-72 marR K Transcriptional regulator, MarR family
LLMDOFAF_00426 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
LLMDOFAF_00427 1.9e-115 S Haloacid dehalogenase-like hydrolase
LLMDOFAF_00428 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
LLMDOFAF_00429 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
LLMDOFAF_00430 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLMDOFAF_00431 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
LLMDOFAF_00432 1.3e-101 ygaC J Belongs to the UPF0374 family
LLMDOFAF_00433 6.4e-108 S Domain of unknown function (DUF1803)
LLMDOFAF_00434 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
LLMDOFAF_00442 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
LLMDOFAF_00443 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
LLMDOFAF_00444 0.0 dnaE 2.7.7.7 L DNA polymerase
LLMDOFAF_00445 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
LLMDOFAF_00446 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LLMDOFAF_00447 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LLMDOFAF_00448 2.5e-43 ysdA L Membrane
LLMDOFAF_00449 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
LLMDOFAF_00450 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LLMDOFAF_00451 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LLMDOFAF_00452 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
LLMDOFAF_00454 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
LLMDOFAF_00455 2.1e-84 ypmS S Protein conserved in bacteria
LLMDOFAF_00456 1.3e-143 ypmR E lipolytic protein G-D-S-L family
LLMDOFAF_00457 1e-148 DegV S DegV family
LLMDOFAF_00458 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
LLMDOFAF_00459 3.7e-73 argR K Regulates arginine biosynthesis genes
LLMDOFAF_00460 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
LLMDOFAF_00461 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
LLMDOFAF_00462 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
LLMDOFAF_00463 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
LLMDOFAF_00466 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LLMDOFAF_00467 2.9e-125 dnaD
LLMDOFAF_00468 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LLMDOFAF_00469 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LLMDOFAF_00470 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
LLMDOFAF_00471 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LLMDOFAF_00472 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
LLMDOFAF_00473 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LLMDOFAF_00474 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LLMDOFAF_00475 5.4e-197 L transposase, IS4 family
LLMDOFAF_00476 5.6e-240 rodA D Belongs to the SEDS family
LLMDOFAF_00477 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
LLMDOFAF_00478 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LLMDOFAF_00479 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
LLMDOFAF_00480 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LLMDOFAF_00481 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LLMDOFAF_00482 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
LLMDOFAF_00483 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LLMDOFAF_00484 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
LLMDOFAF_00485 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LLMDOFAF_00486 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LLMDOFAF_00488 1.6e-32 L Integrase core domain protein
LLMDOFAF_00489 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
LLMDOFAF_00490 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LLMDOFAF_00491 4.6e-238 dltB M Membrane protein involved in D-alanine export
LLMDOFAF_00492 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LLMDOFAF_00493 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
LLMDOFAF_00494 0.0 XK27_10035 V abc transporter atp-binding protein
LLMDOFAF_00495 0.0 yfiB1 V abc transporter atp-binding protein
LLMDOFAF_00496 6e-106 pvaA M lytic transglycosylase activity
LLMDOFAF_00497 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
LLMDOFAF_00498 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LLMDOFAF_00499 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
LLMDOFAF_00500 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
LLMDOFAF_00501 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LLMDOFAF_00502 4.5e-111 tdk 2.7.1.21 F thymidine kinase
LLMDOFAF_00503 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LLMDOFAF_00504 2.4e-155 gst O Glutathione S-transferase
LLMDOFAF_00505 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
LLMDOFAF_00506 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
LLMDOFAF_00507 2e-45 rpmE2 J 50S ribosomal protein L31
LLMDOFAF_00508 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
LLMDOFAF_00509 1.3e-10
LLMDOFAF_00510 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LLMDOFAF_00511 1.8e-135 divIVA D Cell division protein DivIVA
LLMDOFAF_00512 4.2e-144 ylmH T S4 RNA-binding domain
LLMDOFAF_00513 2e-34 yggT D integral membrane protein
LLMDOFAF_00514 1.4e-96 sepF D cell septum assembly
LLMDOFAF_00515 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LLMDOFAF_00516 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LLMDOFAF_00517 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
LLMDOFAF_00518 6.7e-172 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
LLMDOFAF_00519 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LLMDOFAF_00520 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LLMDOFAF_00522 0.0 typA T GTP-binding protein TypA
LLMDOFAF_00523 2.2e-179 glk 2.7.1.2 G Glucokinase
LLMDOFAF_00524 8.4e-28 yqgQ S protein conserved in bacteria
LLMDOFAF_00525 1.1e-80 perR P Belongs to the Fur family
LLMDOFAF_00526 3.2e-92 dps P Belongs to the Dps family
LLMDOFAF_00527 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
LLMDOFAF_00528 4.8e-196 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
LLMDOFAF_00529 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
LLMDOFAF_00530 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
LLMDOFAF_00531 5.5e-153 rarD S Transporter
LLMDOFAF_00532 2.2e-15 T peptidase
LLMDOFAF_00533 8.9e-14 coiA 3.6.4.12 S Competence protein
LLMDOFAF_00534 6.6e-147 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LLMDOFAF_00535 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LLMDOFAF_00536 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
LLMDOFAF_00537 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LLMDOFAF_00538 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
LLMDOFAF_00539 3.3e-78 atpF C ATP synthase F(0) sector subunit b
LLMDOFAF_00540 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LLMDOFAF_00541 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LLMDOFAF_00542 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LLMDOFAF_00543 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LLMDOFAF_00544 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
LLMDOFAF_00545 2.8e-230 ftsW D Belongs to the SEDS family
LLMDOFAF_00546 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LLMDOFAF_00547 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
LLMDOFAF_00548 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LLMDOFAF_00549 6.4e-162 holB 2.7.7.7 L dna polymerase iii
LLMDOFAF_00550 1.2e-135 yaaT S stage 0 sporulation protein
LLMDOFAF_00551 9.5e-55 yabA L Involved in initiation control of chromosome replication
LLMDOFAF_00552 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LLMDOFAF_00553 2.6e-233 amt P Ammonium Transporter
LLMDOFAF_00554 1.1e-53 glnB K Belongs to the P(II) protein family
LLMDOFAF_00555 4.9e-106 mur1 NU mannosyl-glycoprotein
LLMDOFAF_00556 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
LLMDOFAF_00557 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
LLMDOFAF_00558 1.9e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
LLMDOFAF_00559 1.8e-53
LLMDOFAF_00560 7.5e-26
LLMDOFAF_00561 1.5e-59
LLMDOFAF_00562 6.1e-63 S membrane
LLMDOFAF_00563 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
LLMDOFAF_00564 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
LLMDOFAF_00565 4.5e-39 ynzC S UPF0291 protein
LLMDOFAF_00566 1.8e-254 cycA E permease
LLMDOFAF_00567 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
LLMDOFAF_00568 5.8e-71 pts33BCA G pts system
LLMDOFAF_00569 3.5e-143 pts33BCA G pts system
LLMDOFAF_00570 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LLMDOFAF_00571 1.2e-165 L integrase core domain
LLMDOFAF_00572 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
LLMDOFAF_00573 1.9e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
LLMDOFAF_00574 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LLMDOFAF_00575 6.2e-56 S Domain of unknown function (DUF4430)
LLMDOFAF_00576 1.8e-73 S Psort location CytoplasmicMembrane, score
LLMDOFAF_00577 6.4e-133 htpX O Belongs to the peptidase M48B family
LLMDOFAF_00578 9e-93 lemA S LemA family
LLMDOFAF_00579 9.9e-90 spd F DNA RNA non-specific endonuclease
LLMDOFAF_00580 1e-36 spd F DNA RNA non-specific endonuclease
LLMDOFAF_00581 5.9e-22 S PD-(D/E)XK nuclease family transposase
LLMDOFAF_00582 6.6e-306 hsdM 2.1.1.72 V type I restriction-modification system
LLMDOFAF_00583 1e-136 S Protein conserved in bacteria
LLMDOFAF_00584 2.2e-105
LLMDOFAF_00585 2.8e-221 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
LLMDOFAF_00587 1.2e-216 S Bacteriophage abortive infection AbiH
LLMDOFAF_00588 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LLMDOFAF_00589 7.6e-71 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LLMDOFAF_00590 8.7e-45 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
LLMDOFAF_00591 9.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
LLMDOFAF_00592 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
LLMDOFAF_00593 1.6e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LLMDOFAF_00594 2.7e-27 P Hemerythrin HHE cation binding domain protein
LLMDOFAF_00595 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
LLMDOFAF_00596 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LLMDOFAF_00597 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
LLMDOFAF_00598 2.3e-175 S hydrolase
LLMDOFAF_00599 7.6e-16
LLMDOFAF_00600 1e-163 M LysM domain
LLMDOFAF_00601 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
LLMDOFAF_00602 4.2e-117
LLMDOFAF_00603 7.7e-238 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
LLMDOFAF_00604 1.9e-12
LLMDOFAF_00605 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
LLMDOFAF_00606 1.1e-33 XK27_12190 S protein conserved in bacteria
LLMDOFAF_00608 1.5e-89 bioY S biotin synthase
LLMDOFAF_00609 3.4e-252 yegQ O Peptidase U32
LLMDOFAF_00610 4.4e-177 yegQ O Peptidase U32
LLMDOFAF_00612 5.5e-69 ytxH S General stress protein
LLMDOFAF_00614 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LLMDOFAF_00615 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LLMDOFAF_00616 9.9e-42 pspC KT PspC domain
LLMDOFAF_00617 0.0 yhgF K Transcriptional accessory protein
LLMDOFAF_00619 1.7e-157 XK27_03015 S permease
LLMDOFAF_00620 1.3e-148 ycgQ S TIGR03943 family
LLMDOFAF_00621 2.3e-198 S CRISPR-associated protein Csn2 subfamily St
LLMDOFAF_00622 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LLMDOFAF_00623 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LLMDOFAF_00624 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LLMDOFAF_00625 4.4e-93
LLMDOFAF_00626 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
LLMDOFAF_00627 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
LLMDOFAF_00628 1e-31 K Cro/C1-type HTH DNA-binding domain
LLMDOFAF_00629 3.2e-46
LLMDOFAF_00630 8.9e-20
LLMDOFAF_00631 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LLMDOFAF_00632 3.5e-97 mip S hydroperoxide reductase activity
LLMDOFAF_00633 2.4e-203 I acyl-CoA dehydrogenase
LLMDOFAF_00634 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
LLMDOFAF_00635 2.6e-253 msrR K Transcriptional regulator
LLMDOFAF_00636 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
LLMDOFAF_00637 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LLMDOFAF_00638 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
LLMDOFAF_00639 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
LLMDOFAF_00640 3.2e-53 yheA S Belongs to the UPF0342 family
LLMDOFAF_00641 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
LLMDOFAF_00642 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LLMDOFAF_00643 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LLMDOFAF_00644 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LLMDOFAF_00645 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
LLMDOFAF_00646 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
LLMDOFAF_00647 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
LLMDOFAF_00648 2e-25 WQ51_00785
LLMDOFAF_00649 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
LLMDOFAF_00650 1e-78 yueI S Protein of unknown function (DUF1694)
LLMDOFAF_00651 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
LLMDOFAF_00652 6.6e-101 yyaQ V Protein conserved in bacteria
LLMDOFAF_00653 2.8e-28 yyaQ S YjbR
LLMDOFAF_00654 4.4e-183 ccpA K Catabolite control protein A
LLMDOFAF_00655 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
LLMDOFAF_00656 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
LLMDOFAF_00657 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LLMDOFAF_00658 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
LLMDOFAF_00659 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
LLMDOFAF_00660 2.6e-33 secG U Preprotein translocase subunit SecG
LLMDOFAF_00661 9.5e-74 mdtG EGP Major facilitator Superfamily
LLMDOFAF_00662 6e-133 mdtG EGP Major facilitator Superfamily
LLMDOFAF_00663 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LLMDOFAF_00664 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
LLMDOFAF_00665 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LLMDOFAF_00666 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
LLMDOFAF_00667 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LLMDOFAF_00668 6.8e-53 licT K transcriptional antiterminator
LLMDOFAF_00669 9.2e-43 licT K transcriptional antiterminator
LLMDOFAF_00671 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LLMDOFAF_00672 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
LLMDOFAF_00673 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LLMDOFAF_00674 2.1e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LLMDOFAF_00675 7.5e-23 I Alpha/beta hydrolase family
LLMDOFAF_00676 1.5e-35 yugF I carboxylic ester hydrolase activity
LLMDOFAF_00677 2.2e-45 K sequence-specific DNA binding
LLMDOFAF_00678 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LLMDOFAF_00679 1.5e-07
LLMDOFAF_00680 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
LLMDOFAF_00681 1.1e-78 feoA P FeoA domain protein
LLMDOFAF_00682 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
LLMDOFAF_00683 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
LLMDOFAF_00684 1.3e-34 ykuJ S protein conserved in bacteria
LLMDOFAF_00685 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LLMDOFAF_00686 0.0 clpE O Belongs to the ClpA ClpB family
LLMDOFAF_00687 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
LLMDOFAF_00688 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
LLMDOFAF_00689 2.4e-66 S oxidoreductase
LLMDOFAF_00690 1.5e-50 S oxidoreductase
LLMDOFAF_00691 6.8e-234 murN 2.3.2.10, 2.3.2.16 V FemAB family
LLMDOFAF_00692 1.7e-63 M Pfam SNARE associated Golgi protein
LLMDOFAF_00693 1.5e-30 S Domain of Unknown Function with PDB structure (DUF3862)
LLMDOFAF_00694 1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
LLMDOFAF_00697 6.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
LLMDOFAF_00700 4.8e-16 S Protein of unknown function (DUF2969)
LLMDOFAF_00701 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
LLMDOFAF_00702 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LLMDOFAF_00703 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
LLMDOFAF_00704 1.2e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
LLMDOFAF_00705 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LLMDOFAF_00706 4.4e-123 comFC S Competence protein
LLMDOFAF_00707 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LLMDOFAF_00708 6.3e-111 yvyE 3.4.13.9 S YigZ family
LLMDOFAF_00709 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LLMDOFAF_00710 3.3e-43 acuB S IMP dehydrogenase activity
LLMDOFAF_00711 1.1e-69 acuB S IMP dehydrogenase activity
LLMDOFAF_00712 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
LLMDOFAF_00713 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
LLMDOFAF_00714 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
LLMDOFAF_00715 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
LLMDOFAF_00716 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
LLMDOFAF_00717 7.1e-46 ylbG S UPF0298 protein
LLMDOFAF_00718 3.4e-74 ylbF S Belongs to the UPF0342 family
LLMDOFAF_00719 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
LLMDOFAF_00720 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LLMDOFAF_00721 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
LLMDOFAF_00723 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
LLMDOFAF_00724 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
LLMDOFAF_00725 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
LLMDOFAF_00726 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
LLMDOFAF_00727 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LLMDOFAF_00728 3.2e-214 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
LLMDOFAF_00729 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
LLMDOFAF_00730 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
LLMDOFAF_00731 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LLMDOFAF_00732 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LLMDOFAF_00733 1.4e-41 ylxQ J ribosomal protein
LLMDOFAF_00734 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
LLMDOFAF_00735 3.1e-212 nusA K Participates in both transcription termination and antitermination
LLMDOFAF_00736 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
LLMDOFAF_00737 2.5e-220 brpA K Transcriptional
LLMDOFAF_00738 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
LLMDOFAF_00739 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
LLMDOFAF_00740 1.9e-248 pbuO S permease
LLMDOFAF_00741 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
LLMDOFAF_00742 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
LLMDOFAF_00743 1.3e-174 manL 2.7.1.191 G pts system
LLMDOFAF_00744 7e-118 manM G pts system
LLMDOFAF_00745 1.9e-169 manN G PTS system mannose fructose sorbose family IID component
LLMDOFAF_00746 6.5e-63 manO S protein conserved in bacteria
LLMDOFAF_00747 1.5e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LLMDOFAF_00748 1.2e-34
LLMDOFAF_00750 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
LLMDOFAF_00751 5.2e-167 dnaI L Primosomal protein DnaI
LLMDOFAF_00752 6.5e-218 dnaB L Replication initiation and membrane attachment
LLMDOFAF_00753 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LLMDOFAF_00754 2.8e-282 T PhoQ Sensor
LLMDOFAF_00755 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LLMDOFAF_00756 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
LLMDOFAF_00757 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
LLMDOFAF_00758 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
LLMDOFAF_00759 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
LLMDOFAF_00760 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
LLMDOFAF_00761 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LLMDOFAF_00762 1.2e-149 cbiQ P cobalt transport
LLMDOFAF_00763 0.0 ykoD P abc transporter atp-binding protein
LLMDOFAF_00764 9.4e-95 S UPF0397 protein
LLMDOFAF_00765 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
LLMDOFAF_00766 2.7e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LLMDOFAF_00767 3e-98 metI P ABC transporter (Permease
LLMDOFAF_00768 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LLMDOFAF_00769 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
LLMDOFAF_00770 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
LLMDOFAF_00771 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
LLMDOFAF_00772 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
LLMDOFAF_00773 5.3e-153 ET amino acid transport
LLMDOFAF_00774 3.8e-205 EGP Transmembrane secretion effector
LLMDOFAF_00775 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
LLMDOFAF_00776 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
LLMDOFAF_00777 3.3e-118 ET amino acid transport
LLMDOFAF_00778 5.8e-62 L PFAM Integrase, catalytic core
LLMDOFAF_00779 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
LLMDOFAF_00781 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
LLMDOFAF_00782 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
LLMDOFAF_00783 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
LLMDOFAF_00784 3.3e-09 L PFAM Integrase, catalytic core
LLMDOFAF_00785 1.8e-111 L PFAM Integrase, catalytic core
LLMDOFAF_00786 3.3e-62 rplQ J ribosomal protein l17
LLMDOFAF_00787 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LLMDOFAF_00788 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LLMDOFAF_00789 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LLMDOFAF_00790 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
LLMDOFAF_00791 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LLMDOFAF_00792 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
LLMDOFAF_00793 2.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
LLMDOFAF_00794 4.4e-58 rplO J binds to the 23S rRNA
LLMDOFAF_00795 2.5e-23 rpmD J ribosomal protein l30
LLMDOFAF_00796 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LLMDOFAF_00797 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LLMDOFAF_00798 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LLMDOFAF_00799 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LLMDOFAF_00800 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LLMDOFAF_00801 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LLMDOFAF_00802 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LLMDOFAF_00803 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LLMDOFAF_00804 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LLMDOFAF_00805 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
LLMDOFAF_00806 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LLMDOFAF_00807 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LLMDOFAF_00808 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LLMDOFAF_00809 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LLMDOFAF_00810 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LLMDOFAF_00811 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
LLMDOFAF_00812 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
LLMDOFAF_00813 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LLMDOFAF_00814 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
LLMDOFAF_00815 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
LLMDOFAF_00816 0.0 XK27_09800 I Acyltransferase
LLMDOFAF_00817 1.7e-35 XK27_09805 S MORN repeat protein
LLMDOFAF_00818 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LLMDOFAF_00819 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LLMDOFAF_00820 8.8e-83 adk 2.7.4.3 F topology modulation protein
LLMDOFAF_00821 3.1e-172 yxaM EGP Major facilitator Superfamily
LLMDOFAF_00822 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
LLMDOFAF_00823 0.0 3.6.3.8 P cation transport ATPase
LLMDOFAF_00824 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
LLMDOFAF_00826 3e-44 ymbI L transposase activity
LLMDOFAF_00827 4e-22 L Belongs to the 'phage' integrase family
LLMDOFAF_00828 1.4e-66 S tRNA_anti-like
LLMDOFAF_00829 2e-103
LLMDOFAF_00831 5e-12
LLMDOFAF_00833 2e-296 S DNA primase
LLMDOFAF_00834 3e-164 KL Phage plasmid primase P4 family
LLMDOFAF_00835 6.9e-22
LLMDOFAF_00836 9.2e-13
LLMDOFAF_00841 1.3e-17 K Cro/C1-type HTH DNA-binding domain
LLMDOFAF_00843 1.1e-220 sip L Belongs to the 'phage' integrase family
LLMDOFAF_00845 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LLMDOFAF_00846 7.3e-166 metF 1.5.1.20 E reductase
LLMDOFAF_00847 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
LLMDOFAF_00848 1.7e-94 panT S ECF transporter, substrate-specific component
LLMDOFAF_00849 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LLMDOFAF_00850 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
LLMDOFAF_00851 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
LLMDOFAF_00852 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LLMDOFAF_00853 2.8e-40 T PhoQ Sensor
LLMDOFAF_00854 1.7e-43 T PhoQ Sensor
LLMDOFAF_00855 5.8e-79 T PhoQ Sensor
LLMDOFAF_00856 2.2e-61 rlpA M LysM domain protein
LLMDOFAF_00857 8e-191 phoH T phosphate starvation-inducible protein PhoH
LLMDOFAF_00861 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LLMDOFAF_00862 1.8e-167 K transcriptional regulator (lysR family)
LLMDOFAF_00863 1.4e-186 coiA 3.6.4.12 S Competence protein
LLMDOFAF_00864 0.0 pepF E oligoendopeptidase F
LLMDOFAF_00865 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
LLMDOFAF_00866 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
LLMDOFAF_00867 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LLMDOFAF_00868 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LLMDOFAF_00869 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LLMDOFAF_00870 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
LLMDOFAF_00871 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
LLMDOFAF_00872 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
LLMDOFAF_00873 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
LLMDOFAF_00874 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LLMDOFAF_00875 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LLMDOFAF_00876 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
LLMDOFAF_00877 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
LLMDOFAF_00878 8.5e-142 yxkH G deacetylase
LLMDOFAF_00879 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
LLMDOFAF_00880 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LLMDOFAF_00881 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
LLMDOFAF_00882 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
LLMDOFAF_00883 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
LLMDOFAF_00885 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LLMDOFAF_00887 6.5e-63 KT phosphorelay signal transduction system
LLMDOFAF_00888 1.9e-80 S Protein of unknown function (DUF3021)
LLMDOFAF_00889 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LLMDOFAF_00890 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
LLMDOFAF_00891 8.2e-70 argR K Regulates arginine biosynthesis genes
LLMDOFAF_00892 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LLMDOFAF_00893 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LLMDOFAF_00894 9.2e-141 1.1.1.169 H Ketopantoate reductase
LLMDOFAF_00895 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LLMDOFAF_00896 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LLMDOFAF_00897 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
LLMDOFAF_00898 2.3e-161 S CHAP domain
LLMDOFAF_00899 2e-32 L Integrase core domain protein
LLMDOFAF_00900 3.5e-50 L transposition
LLMDOFAF_00901 1.4e-20 L transposase activity
LLMDOFAF_00908 5.3e-11
LLMDOFAF_00914 1.3e-140 mreC M Involved in formation and maintenance of cell shape
LLMDOFAF_00915 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LLMDOFAF_00916 8.9e-102 usp 3.5.1.28 CBM50 S CHAP domain
LLMDOFAF_00917 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LLMDOFAF_00918 2.5e-26
LLMDOFAF_00919 5.9e-219 araT 2.6.1.1 E Aminotransferase
LLMDOFAF_00920 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
LLMDOFAF_00921 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
LLMDOFAF_00922 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
LLMDOFAF_00923 5.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
LLMDOFAF_00924 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LLMDOFAF_00925 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LLMDOFAF_00926 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
LLMDOFAF_00927 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LLMDOFAF_00928 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
LLMDOFAF_00929 4.2e-44 yrzB S Belongs to the UPF0473 family
LLMDOFAF_00930 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LLMDOFAF_00931 2.8e-44 yrzL S Belongs to the UPF0297 family
LLMDOFAF_00932 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
LLMDOFAF_00933 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
LLMDOFAF_00935 3.5e-216 int L Belongs to the 'phage' integrase family
LLMDOFAF_00936 1.9e-18 S Domain of unknown function (DUF3173)
LLMDOFAF_00937 1.4e-107 L Replication initiation factor
LLMDOFAF_00938 1e-36 L Replication initiation factor
LLMDOFAF_00939 1.7e-90 K sequence-specific DNA binding
LLMDOFAF_00940 3.9e-287 V ABC transporter transmembrane region
LLMDOFAF_00941 3.4e-191 C Radical SAM
LLMDOFAF_00943 1.4e-127 Z012_04635 K sequence-specific DNA binding
LLMDOFAF_00944 2.1e-280 V ABC transporter
LLMDOFAF_00945 0.0 KLT serine threonine protein kinase
LLMDOFAF_00946 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LLMDOFAF_00948 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LLMDOFAF_00949 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
LLMDOFAF_00950 6.9e-144 S SseB protein N-terminal domain
LLMDOFAF_00951 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
LLMDOFAF_00952 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
LLMDOFAF_00953 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LLMDOFAF_00956 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLMDOFAF_00957 3.5e-91 yacP S RNA-binding protein containing a PIN domain
LLMDOFAF_00958 3.4e-155 degV S DegV family
LLMDOFAF_00959 1.8e-31 K helix-turn-helix
LLMDOFAF_00960 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LLMDOFAF_00961 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LLMDOFAF_00962 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
LLMDOFAF_00963 1.5e-35 K sequence-specific DNA binding
LLMDOFAF_00965 0.0
LLMDOFAF_00966 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
LLMDOFAF_00967 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
LLMDOFAF_00968 2.9e-18 yebC M Membrane
LLMDOFAF_00969 2.6e-80 yebC M Membrane
LLMDOFAF_00970 3.6e-66 KT response to antibiotic
LLMDOFAF_00971 5.2e-75 XK27_02470 K LytTr DNA-binding domain
LLMDOFAF_00972 2.6e-121 liaI S membrane
LLMDOFAF_00973 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LLMDOFAF_00974 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
LLMDOFAF_00975 1.6e-11 S Protein of unknown function (DUF554)
LLMDOFAF_00976 8.5e-32 S Protein of unknown function (DUF554)
LLMDOFAF_00977 2.5e-47 S Protein of unknown function (DUF554)
LLMDOFAF_00978 1.4e-133 ecsA_2 V abc transporter atp-binding protein
LLMDOFAF_00979 6.2e-288 XK27_00765
LLMDOFAF_00980 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LLMDOFAF_00981 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LLMDOFAF_00982 1.3e-08 D nuclear chromosome segregation
LLMDOFAF_00983 9.7e-32 yhaI J Protein of unknown function (DUF805)
LLMDOFAF_00985 2.6e-30
LLMDOFAF_00986 7.4e-27
LLMDOFAF_00987 1.6e-65
LLMDOFAF_00988 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
LLMDOFAF_00989 4.3e-47 ftsL D cell division protein FtsL
LLMDOFAF_00990 0.0 ftsI 3.4.16.4 M penicillin-binding protein
LLMDOFAF_00991 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LLMDOFAF_00992 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
LLMDOFAF_00994 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
LLMDOFAF_00995 3.6e-70 yutD J protein conserved in bacteria
LLMDOFAF_00996 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
LLMDOFAF_00997 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
LLMDOFAF_00999 9.1e-303 mdlA V abc transporter atp-binding protein
LLMDOFAF_01000 0.0 mdlB V abc transporter atp-binding protein
LLMDOFAF_01001 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LLMDOFAF_01002 7.3e-237 mesE M Transport protein ComB
LLMDOFAF_01004 3.4e-239 blpH 2.7.13.3 T protein histidine kinase activity
LLMDOFAF_01005 7.4e-135 agrA KT phosphorelay signal transduction system
LLMDOFAF_01009 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
LLMDOFAF_01016 6.7e-98 blpT
LLMDOFAF_01017 2.9e-28 blpT
LLMDOFAF_01018 3e-47 spiA K sequence-specific DNA binding
LLMDOFAF_01021 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
LLMDOFAF_01022 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
LLMDOFAF_01023 5e-44 V CAAX protease self-immunity
LLMDOFAF_01024 4.6e-140 cppA E CppA N-terminal
LLMDOFAF_01025 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
LLMDOFAF_01026 1.2e-117 ybbL S abc transporter atp-binding protein
LLMDOFAF_01027 1.5e-127 ybbM S transport system, permease component
LLMDOFAF_01028 2.9e-87 D nuclear chromosome segregation
LLMDOFAF_01029 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
LLMDOFAF_01030 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LLMDOFAF_01031 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
LLMDOFAF_01032 0.0 pflB 2.3.1.54 C formate acetyltransferase'
LLMDOFAF_01033 1.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLMDOFAF_01035 1.2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LLMDOFAF_01036 4.7e-163 yxeN P ABC transporter (Permease
LLMDOFAF_01037 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
LLMDOFAF_01038 1.9e-09 S Protein of unknown function (DUF4059)
LLMDOFAF_01039 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
LLMDOFAF_01040 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
LLMDOFAF_01041 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LLMDOFAF_01042 2.2e-196 ylbL T Belongs to the peptidase S16 family
LLMDOFAF_01043 1.3e-184 yhcC S radical SAM protein
LLMDOFAF_01044 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
LLMDOFAF_01046 0.0 yjcE P NhaP-type Na H and K H antiporters
LLMDOFAF_01047 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
LLMDOFAF_01048 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
LLMDOFAF_01049 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LLMDOFAF_01052 2.4e-75 XK27_03180 T universal stress protein
LLMDOFAF_01053 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
LLMDOFAF_01054 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LLMDOFAF_01055 6.8e-101 pncA Q isochorismatase
LLMDOFAF_01056 1.6e-154 hlpA M Belongs to the NlpA lipoprotein family
LLMDOFAF_01057 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLMDOFAF_01058 1.3e-251 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LLMDOFAF_01059 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LLMDOFAF_01060 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
LLMDOFAF_01061 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LLMDOFAF_01062 3.5e-13
LLMDOFAF_01063 5.8e-24
LLMDOFAF_01064 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
LLMDOFAF_01065 1.8e-98 yqeG S hydrolase of the HAD superfamily
LLMDOFAF_01066 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
LLMDOFAF_01067 3.5e-49 yhbY J RNA-binding protein
LLMDOFAF_01068 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LLMDOFAF_01069 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
LLMDOFAF_01070 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
LLMDOFAF_01071 2e-140 yqeM Q Methyltransferase domain protein
LLMDOFAF_01072 6.9e-206 ylbM S Belongs to the UPF0348 family
LLMDOFAF_01073 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
LLMDOFAF_01074 3.2e-110
LLMDOFAF_01075 1.3e-56 S CD20-like family
LLMDOFAF_01076 6e-11
LLMDOFAF_01077 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
LLMDOFAF_01078 2.3e-133 ecsA V abc transporter atp-binding protein
LLMDOFAF_01079 2.7e-183 ecsB U ABC transporter
LLMDOFAF_01080 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
LLMDOFAF_01081 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
LLMDOFAF_01083 7.7e-227 ytfP S Flavoprotein
LLMDOFAF_01084 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
LLMDOFAF_01085 7.4e-64 XK27_02560 S cog cog2151
LLMDOFAF_01086 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
LLMDOFAF_01087 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
LLMDOFAF_01088 1.4e-81 K transcriptional regulator, MerR family
LLMDOFAF_01089 5.1e-47 L transposase activity
LLMDOFAF_01090 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LLMDOFAF_01091 3.9e-26
LLMDOFAF_01092 0.0 ctpE P E1-E2 ATPase
LLMDOFAF_01093 1.4e-54
LLMDOFAF_01094 2.1e-30 rpsT J rRNA binding
LLMDOFAF_01095 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
LLMDOFAF_01096 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
LLMDOFAF_01097 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LLMDOFAF_01098 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
LLMDOFAF_01099 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LLMDOFAF_01100 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LLMDOFAF_01101 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
LLMDOFAF_01102 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
LLMDOFAF_01103 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
LLMDOFAF_01104 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
LLMDOFAF_01105 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
LLMDOFAF_01106 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
LLMDOFAF_01107 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
LLMDOFAF_01108 3.1e-81 ypmB S Protein conserved in bacteria
LLMDOFAF_01109 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
LLMDOFAF_01110 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
LLMDOFAF_01111 9e-08
LLMDOFAF_01112 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
LLMDOFAF_01113 3.1e-10 L thioesterase
LLMDOFAF_01114 7.8e-143 S Macro domain protein
LLMDOFAF_01115 4.8e-51 trxA O Belongs to the thioredoxin family
LLMDOFAF_01116 2.5e-26 yccU S CoA-binding protein
LLMDOFAF_01117 1.4e-144 tatD L Hydrolase, tatd
LLMDOFAF_01118 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
LLMDOFAF_01119 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
LLMDOFAF_01121 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
LLMDOFAF_01122 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
LLMDOFAF_01123 1.8e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
LLMDOFAF_01124 6.9e-173 rmuC S RmuC domain protein
LLMDOFAF_01125 1.8e-178 cbf S 3'-5' exoribonuclease yhaM
LLMDOFAF_01126 1.1e-142 purR 2.4.2.7 F operon repressor
LLMDOFAF_01127 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LLMDOFAF_01128 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
LLMDOFAF_01129 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LLMDOFAF_01130 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
LLMDOFAF_01131 7.4e-35 yozE S Belongs to the UPF0346 family
LLMDOFAF_01132 5.3e-161 cvfB S Protein conserved in bacteria
LLMDOFAF_01133 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
LLMDOFAF_01134 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
LLMDOFAF_01135 2.9e-120 sptS 2.7.13.3 T Histidine kinase
LLMDOFAF_01136 1.6e-44 K Acetyltransferase (GNAT) family
LLMDOFAF_01137 0.0 lmrA2 V abc transporter atp-binding protein
LLMDOFAF_01138 0.0 lmrA1 V abc transporter atp-binding protein
LLMDOFAF_01139 1.9e-77 K DNA-binding transcription factor activity
LLMDOFAF_01140 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
LLMDOFAF_01141 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
LLMDOFAF_01142 2.1e-204 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
LLMDOFAF_01143 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
LLMDOFAF_01144 1.6e-24 U response to pH
LLMDOFAF_01146 3.3e-95 ywlG S Belongs to the UPF0340 family
LLMDOFAF_01147 1.2e-85 treR K trehalose operon
LLMDOFAF_01148 5.8e-21 treR K DNA-binding transcription factor activity
LLMDOFAF_01149 1.4e-54 treB 2.7.1.201 G PTS System
LLMDOFAF_01150 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LLMDOFAF_01151 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LLMDOFAF_01152 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
LLMDOFAF_01153 4e-226 pepO 3.4.24.71 O Peptidase family M13
LLMDOFAF_01154 1.7e-133 pepO 3.4.24.71 O Peptidase family M13
LLMDOFAF_01155 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
LLMDOFAF_01156 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LLMDOFAF_01157 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LLMDOFAF_01158 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
LLMDOFAF_01159 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
LLMDOFAF_01160 9.2e-278 thrC 4.2.3.1 E Threonine synthase
LLMDOFAF_01161 3.2e-226 norN V Mate efflux family protein
LLMDOFAF_01162 1.8e-57 asp S cog cog1302
LLMDOFAF_01163 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
LLMDOFAF_01164 1.1e-29 yyzM S Protein conserved in bacteria
LLMDOFAF_01165 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
LLMDOFAF_01166 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
LLMDOFAF_01167 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LLMDOFAF_01168 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
LLMDOFAF_01169 2.7e-61 divIC D Septum formation initiator
LLMDOFAF_01171 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
LLMDOFAF_01172 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
LLMDOFAF_01173 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
LLMDOFAF_01174 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LLMDOFAF_01175 2.4e-164 L Transposase
LLMDOFAF_01176 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
LLMDOFAF_01177 4.3e-109 capA M Bacterial capsule synthesis protein
LLMDOFAF_01178 1.5e-55 capA M Bacterial capsule synthesis protein
LLMDOFAF_01179 3.6e-39 gcvR T UPF0237 protein
LLMDOFAF_01180 1.7e-243 XK27_08635 S UPF0210 protein
LLMDOFAF_01181 2.4e-135 ais G Phosphoglycerate mutase
LLMDOFAF_01182 2.1e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
LLMDOFAF_01183 1.3e-102 acmA 3.2.1.17 NU amidase activity
LLMDOFAF_01184 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
LLMDOFAF_01185 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LLMDOFAF_01186 7.5e-298 dnaK O Heat shock 70 kDa protein
LLMDOFAF_01187 3.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
LLMDOFAF_01188 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
LLMDOFAF_01189 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
LLMDOFAF_01190 3.8e-31 hmpT S membrane
LLMDOFAF_01195 1.8e-167 fhuR K transcriptional regulator (lysR family)
LLMDOFAF_01196 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LLMDOFAF_01197 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LLMDOFAF_01198 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LLMDOFAF_01199 4.9e-227 pyrP F uracil Permease
LLMDOFAF_01200 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
LLMDOFAF_01201 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
LLMDOFAF_01202 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
LLMDOFAF_01203 8.4e-190 L Transposase
LLMDOFAF_01204 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
LLMDOFAF_01205 8.9e-206 potD P spermidine putrescine ABC transporter
LLMDOFAF_01206 3.1e-268 clcA P Chloride transporter, ClC family
LLMDOFAF_01207 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
LLMDOFAF_01208 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
LLMDOFAF_01209 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LLMDOFAF_01210 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
LLMDOFAF_01211 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
LLMDOFAF_01212 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
LLMDOFAF_01213 7.7e-20 D nuclear chromosome segregation
LLMDOFAF_01214 7.4e-138 yejC S cyclic nucleotide-binding protein
LLMDOFAF_01215 1.2e-163 rapZ S Displays ATPase and GTPase activities
LLMDOFAF_01216 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
LLMDOFAF_01217 8.7e-162 whiA K May be required for sporulation
LLMDOFAF_01218 2.8e-90 pepD E Dipeptidase
LLMDOFAF_01219 5.8e-41 pepD E dipeptidase activity
LLMDOFAF_01220 5.4e-32 cspD K Cold shock protein domain
LLMDOFAF_01221 9.4e-43 K Cold-Shock Protein
LLMDOFAF_01222 1.4e-96 V VanZ like family
LLMDOFAF_01223 7.6e-70 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
LLMDOFAF_01224 3.5e-29 G Belongs to the phosphoglycerate mutase family
LLMDOFAF_01225 3.9e-61 G Belongs to the phosphoglycerate mutase family
LLMDOFAF_01226 1.3e-199 S hmm pf01594
LLMDOFAF_01227 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LLMDOFAF_01228 3.5e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LLMDOFAF_01229 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
LLMDOFAF_01230 4.9e-39 S granule-associated protein
LLMDOFAF_01231 2e-294 S unusual protein kinase
LLMDOFAF_01232 2.6e-15 estA E Lysophospholipase L1 and related esterases
LLMDOFAF_01233 6.1e-79 estA E GDSL-like protein
LLMDOFAF_01234 1.3e-159 rssA S Phospholipase, patatin family
LLMDOFAF_01235 1.3e-125 3.4.16.4 M Belongs to the peptidase S11 family
LLMDOFAF_01236 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
LLMDOFAF_01237 3.8e-17 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
LLMDOFAF_01238 3e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LLMDOFAF_01239 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LLMDOFAF_01240 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
LLMDOFAF_01241 4.4e-66 S the current gene model (or a revised gene model) may contain a frame shift
LLMDOFAF_01242 1.1e-37 P membrane protein (DUF2207)
LLMDOFAF_01243 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
LLMDOFAF_01244 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
LLMDOFAF_01245 1.1e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
LLMDOFAF_01246 0.0 lpdA 1.8.1.4 C Dehydrogenase
LLMDOFAF_01247 6.4e-11 3.5.1.28 NU amidase activity
LLMDOFAF_01248 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
LLMDOFAF_01249 8.6e-187 3.5.1.28 M GBS Bsp-like repeat
LLMDOFAF_01250 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LLMDOFAF_01251 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LLMDOFAF_01252 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LLMDOFAF_01253 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LLMDOFAF_01254 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
LLMDOFAF_01255 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLMDOFAF_01256 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LLMDOFAF_01257 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
LLMDOFAF_01258 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
LLMDOFAF_01259 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
LLMDOFAF_01260 8.7e-234 ycdB P peroxidase
LLMDOFAF_01261 7.2e-303 ywbL P COG0672 High-affinity Fe2 Pb2 permease
LLMDOFAF_01262 9e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LLMDOFAF_01263 4.6e-25 tatA U protein secretion
LLMDOFAF_01264 2.3e-23 L Transposase
LLMDOFAF_01265 1.2e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
LLMDOFAF_01266 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
LLMDOFAF_01269 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
LLMDOFAF_01270 8.3e-196 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
LLMDOFAF_01271 0.0 pepN 3.4.11.2 E aminopeptidase
LLMDOFAF_01272 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
LLMDOFAF_01273 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LLMDOFAF_01274 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
LLMDOFAF_01275 1.2e-155 pstA P phosphate transport system permease
LLMDOFAF_01276 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
LLMDOFAF_01277 3.3e-158 pstS P phosphate
LLMDOFAF_01278 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
LLMDOFAF_01279 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
LLMDOFAF_01280 1.9e-43 yktA S Belongs to the UPF0223 family
LLMDOFAF_01281 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
LLMDOFAF_01282 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
LLMDOFAF_01283 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LLMDOFAF_01284 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
LLMDOFAF_01285 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
LLMDOFAF_01286 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
LLMDOFAF_01287 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LLMDOFAF_01288 9.3e-62 S haloacid dehalogenase-like hydrolase
LLMDOFAF_01289 1.8e-59 Q phosphatase activity
LLMDOFAF_01290 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
LLMDOFAF_01291 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
LLMDOFAF_01292 1.8e-240 agcS E (Alanine) symporter
LLMDOFAF_01293 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LLMDOFAF_01294 4e-99 yfiF3 K sequence-specific DNA binding
LLMDOFAF_01295 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
LLMDOFAF_01296 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
LLMDOFAF_01298 2.3e-20 yecS P amino acid transport
LLMDOFAF_01299 1.4e-62 yecS P ABC transporter (Permease
LLMDOFAF_01300 1.6e-266 dtpT E transporter
LLMDOFAF_01301 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LLMDOFAF_01302 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
LLMDOFAF_01303 9.5e-32 csm6 S Psort location Cytoplasmic, score
LLMDOFAF_01305 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
LLMDOFAF_01306 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
LLMDOFAF_01307 1.6e-117 csm3 L RAMP superfamily
LLMDOFAF_01308 2.5e-62 csm2 L Csm2 Type III-A
LLMDOFAF_01309 1.2e-210 csm1 S CRISPR-associated protein Csm1 family
LLMDOFAF_01310 1.1e-204 csm1 S CRISPR-associated protein Csm1 family
LLMDOFAF_01311 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
LLMDOFAF_01312 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LLMDOFAF_01313 6e-188 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LLMDOFAF_01314 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
LLMDOFAF_01315 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
LLMDOFAF_01316 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
LLMDOFAF_01317 4.3e-118 S TraX protein
LLMDOFAF_01319 3.5e-28 3.4.13.21 I Protein conserved in bacteria
LLMDOFAF_01320 8.1e-90 FNV0100 F Belongs to the Nudix hydrolase family
LLMDOFAF_01321 3.7e-190
LLMDOFAF_01322 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
LLMDOFAF_01324 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
LLMDOFAF_01325 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
LLMDOFAF_01326 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
LLMDOFAF_01327 1.2e-143 2.4.2.3 F Phosphorylase superfamily
LLMDOFAF_01330 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
LLMDOFAF_01331 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
LLMDOFAF_01332 6e-08 S Hydrolases of the alpha beta superfamily
LLMDOFAF_01333 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
LLMDOFAF_01334 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
LLMDOFAF_01335 1.8e-159 czcD P cation diffusion facilitator family transporter
LLMDOFAF_01336 9e-98 K Transcriptional regulator, TetR family
LLMDOFAF_01337 1.6e-10
LLMDOFAF_01338 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
LLMDOFAF_01339 6.4e-104 V ABC transporter (Permease
LLMDOFAF_01340 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
LLMDOFAF_01341 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
LLMDOFAF_01343 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
LLMDOFAF_01344 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LLMDOFAF_01345 5.5e-83 S Putative small multi-drug export protein
LLMDOFAF_01346 1.8e-75 ctsR K Belongs to the CtsR family
LLMDOFAF_01347 0.0 clpC O Belongs to the ClpA ClpB family
LLMDOFAF_01348 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LLMDOFAF_01349 1.7e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
LLMDOFAF_01350 3.5e-97 S reductase
LLMDOFAF_01351 2.6e-55 badR K DNA-binding transcription factor activity
LLMDOFAF_01352 1.9e-36 XK27_02060 S Transglycosylase associated protein
LLMDOFAF_01353 2.3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
LLMDOFAF_01354 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LLMDOFAF_01359 1.9e-07
LLMDOFAF_01360 1.9e-57 L Transposase
LLMDOFAF_01362 0.0 ddpA E ABC transporter substrate-binding protein
LLMDOFAF_01363 2.8e-188 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
LLMDOFAF_01364 1.8e-141 dppC P N-terminal TM domain of oligopeptide transport permease C
LLMDOFAF_01365 0.0 P Belongs to the ABC transporter superfamily
LLMDOFAF_01366 3e-13 mesE M Transport protein ComB
LLMDOFAF_01367 2.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
LLMDOFAF_01368 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
LLMDOFAF_01369 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
LLMDOFAF_01370 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
LLMDOFAF_01371 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
LLMDOFAF_01372 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LLMDOFAF_01373 8.2e-28 ytrF V efflux transmembrane transporter activity
LLMDOFAF_01374 3.1e-31 V efflux transmembrane transporter activity
LLMDOFAF_01375 3.6e-35 V efflux transmembrane transporter activity
LLMDOFAF_01376 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
LLMDOFAF_01377 1.8e-127 tnp L Transposase
LLMDOFAF_01378 2e-20 S phage tail
LLMDOFAF_01379 7.1e-130 S EcsC protein family
LLMDOFAF_01380 2.4e-23 S phage tail tape measure protein
LLMDOFAF_01381 9.8e-71 L Phage integrase family
LLMDOFAF_01383 1.9e-225 nodC 2.4.1.212 GT2 M Chitin synthase
LLMDOFAF_01384 2.4e-214 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LLMDOFAF_01385 0.0 copB 3.6.3.4 P P-type ATPase
LLMDOFAF_01386 0.0 amiA E ABC transporter, substrate-binding protein, family 5
LLMDOFAF_01387 8.1e-45 L Transposase
LLMDOFAF_01388 4.1e-158 L COG2801 Transposase and inactivated derivatives
LLMDOFAF_01389 1e-23 oppF P Belongs to the ABC transporter superfamily
LLMDOFAF_01390 3.8e-45 oppF P Belongs to the ABC transporter superfamily
LLMDOFAF_01391 1.4e-40 tatD L Hydrolase, tatd
LLMDOFAF_01392 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
LLMDOFAF_01393 1e-110 L Integrase core domain protein
LLMDOFAF_01394 4.3e-23 L Transposase
LLMDOFAF_01395 8.9e-18 L transposase activity
LLMDOFAF_01396 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
LLMDOFAF_01397 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
LLMDOFAF_01398 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LLMDOFAF_01399 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
LLMDOFAF_01400 1.5e-103 yjbK S Adenylate cyclase
LLMDOFAF_01401 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LLMDOFAF_01402 2.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
LLMDOFAF_01403 3.1e-59 XK27_04120 S Putative amino acid metabolism
LLMDOFAF_01404 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LLMDOFAF_01405 7.2e-132 puuD T peptidase C26
LLMDOFAF_01406 1.2e-115 radC E Belongs to the UPF0758 family
LLMDOFAF_01407 1.7e-268 M Psort location CytoplasmicMembrane, score
LLMDOFAF_01408 0.0 rgpF M Rhamnan synthesis protein F
LLMDOFAF_01409 2e-305 GT4 M transferase activity, transferring glycosyl groups
LLMDOFAF_01410 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
LLMDOFAF_01411 2.1e-143 rgpC GM Transport permease protein
LLMDOFAF_01412 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
LLMDOFAF_01413 1.8e-228 rgpA GT4 M Domain of unknown function (DUF1972)
LLMDOFAF_01414 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
LLMDOFAF_01415 4.6e-42 S Uncharacterized conserved protein (DUF2304)
LLMDOFAF_01416 6.9e-130 arnC M group 2 family protein
LLMDOFAF_01417 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
LLMDOFAF_01418 9.3e-186 S Glycosyltransferase like family 2
LLMDOFAF_01419 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
LLMDOFAF_01420 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
LLMDOFAF_01421 5.3e-237 S Predicted membrane protein (DUF2142)
LLMDOFAF_01422 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
LLMDOFAF_01423 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
LLMDOFAF_01424 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
LLMDOFAF_01425 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
LLMDOFAF_01426 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
LLMDOFAF_01427 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
LLMDOFAF_01428 1.6e-202 arcT 2.6.1.1 E Aminotransferase
LLMDOFAF_01429 6.5e-137 ET ABC transporter
LLMDOFAF_01430 7.5e-144 ET Belongs to the bacterial solute-binding protein 3 family
LLMDOFAF_01431 2.9e-84 mutT 3.6.1.55 F Nudix family
LLMDOFAF_01432 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
LLMDOFAF_01433 2.5e-56 V CAAX protease self-immunity
LLMDOFAF_01434 2.4e-33 S CAAX amino terminal protease family protein
LLMDOFAF_01435 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
LLMDOFAF_01436 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
LLMDOFAF_01437 1.1e-16 XK27_00735
LLMDOFAF_01438 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LLMDOFAF_01440 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LLMDOFAF_01443 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
LLMDOFAF_01444 4.7e-51 ycaO O OsmC-like protein
LLMDOFAF_01445 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
LLMDOFAF_01447 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
LLMDOFAF_01448 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LLMDOFAF_01449 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LLMDOFAF_01450 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
LLMDOFAF_01451 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
LLMDOFAF_01452 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LLMDOFAF_01453 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LLMDOFAF_01454 2.6e-109 3.1.3.18 S IA, variant 1
LLMDOFAF_01455 2.2e-117 lrgB M effector of murein hydrolase
LLMDOFAF_01456 7.7e-56 lrgA S Effector of murein hydrolase LrgA
LLMDOFAF_01458 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
LLMDOFAF_01459 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
LLMDOFAF_01460 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LLMDOFAF_01461 3.9e-104 wecD M Acetyltransferase GNAT family
LLMDOFAF_01462 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LLMDOFAF_01463 4.6e-58 GK ROK family
LLMDOFAF_01464 2.1e-25 GK ROK family
LLMDOFAF_01465 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
LLMDOFAF_01466 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
LLMDOFAF_01467 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
LLMDOFAF_01468 2.3e-206 potD P spermidine putrescine ABC transporter
LLMDOFAF_01469 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
LLMDOFAF_01470 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
LLMDOFAF_01471 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
LLMDOFAF_01472 7.8e-171 murB 1.3.1.98 M cell wall formation
LLMDOFAF_01473 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LLMDOFAF_01474 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LLMDOFAF_01475 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
LLMDOFAF_01476 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LLMDOFAF_01477 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
LLMDOFAF_01478 0.0 ydaO E amino acid
LLMDOFAF_01479 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
LLMDOFAF_01480 4.1e-37 ylqC L Belongs to the UPF0109 family
LLMDOFAF_01481 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
LLMDOFAF_01482 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
LLMDOFAF_01483 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
LLMDOFAF_01484 2.1e-74 S QueT transporter
LLMDOFAF_01485 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
LLMDOFAF_01486 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
LLMDOFAF_01487 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
LLMDOFAF_01488 1.4e-92 3.6.4.12 K Divergent AAA domain protein
LLMDOFAF_01489 5.9e-24 3.6.4.12
LLMDOFAF_01490 7.7e-112 EGP Major facilitator Superfamily
LLMDOFAF_01491 4.7e-56 EGP Major facilitator Superfamily
LLMDOFAF_01492 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
LLMDOFAF_01493 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
LLMDOFAF_01494 3e-246 cps1C S Polysaccharide biosynthesis protein
LLMDOFAF_01495 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
LLMDOFAF_01496 4.7e-115 hrtB V MacB-like periplasmic core domain
LLMDOFAF_01497 1.6e-18 L Integrase core domain
LLMDOFAF_01500 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
LLMDOFAF_01501 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
LLMDOFAF_01503 3.2e-17 S Domain of unknown function (DUF4649)
LLMDOFAF_01504 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
LLMDOFAF_01505 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
LLMDOFAF_01506 1.2e-135 XK27_08845 S abc transporter atp-binding protein
LLMDOFAF_01507 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LLMDOFAF_01508 9.2e-152 estA CE1 S Putative esterase
LLMDOFAF_01509 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
LLMDOFAF_01510 5.5e-14 XK27_08880
LLMDOFAF_01511 2.3e-75 fld C Flavodoxin
LLMDOFAF_01512 6.4e-282 clcA P Chloride transporter, ClC family
LLMDOFAF_01513 5.1e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
LLMDOFAF_01514 3.2e-220 XK27_05110 P chloride
LLMDOFAF_01515 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
LLMDOFAF_01518 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
LLMDOFAF_01519 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LLMDOFAF_01520 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
LLMDOFAF_01521 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LLMDOFAF_01522 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
LLMDOFAF_01523 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LLMDOFAF_01524 0.0 5.1.3.2 GM Psort location CytoplasmicMembrane, score
LLMDOFAF_01525 2.2e-168
LLMDOFAF_01526 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
LLMDOFAF_01527 4.3e-277 pelF GT4 M Domain of unknown function (DUF3492)
LLMDOFAF_01528 3.8e-199 pelG M Putative exopolysaccharide Exporter (EPS-E)
LLMDOFAF_01529 2.3e-49 pelG S Putative exopolysaccharide Exporter (EPS-E)
LLMDOFAF_01530 1.5e-211 cotH M CotH kinase protein
LLMDOFAF_01531 8.4e-53 G Domain of unknown function (DUF4832)
LLMDOFAF_01532 2.2e-21 G Domain of unknown function (DUF4832)
LLMDOFAF_01533 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LLMDOFAF_01535 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LLMDOFAF_01536 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
LLMDOFAF_01537 2.4e-124 endA F DNA RNA non-specific endonuclease
LLMDOFAF_01538 1.7e-111 tcyB_2 P ABC transporter (permease)
LLMDOFAF_01539 5.9e-118 gltJ P ABC transporter (Permease
LLMDOFAF_01540 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
LLMDOFAF_01541 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
LLMDOFAF_01542 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LLMDOFAF_01543 1.5e-247 vicK 2.7.13.3 T Histidine kinase
LLMDOFAF_01544 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
LLMDOFAF_01545 1.8e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
LLMDOFAF_01546 1.2e-146 yidA S hydrolases of the HAD superfamily
LLMDOFAF_01547 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
LLMDOFAF_01548 2.6e-67 ywiB S Domain of unknown function (DUF1934)
LLMDOFAF_01549 0.0 pacL 3.6.3.8 P cation transport ATPase
LLMDOFAF_01550 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
LLMDOFAF_01551 1.1e-180 yjjH S Calcineurin-like phosphoesterase
LLMDOFAF_01552 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LLMDOFAF_01553 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LLMDOFAF_01554 2.5e-124 ftsE D cell division ATP-binding protein FtsE
LLMDOFAF_01555 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
LLMDOFAF_01556 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
LLMDOFAF_01557 6.2e-176 yubA S permease
LLMDOFAF_01558 3.7e-224 G COG0457 FOG TPR repeat
LLMDOFAF_01559 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
LLMDOFAF_01560 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
LLMDOFAF_01561 2.9e-90 ebsA S Family of unknown function (DUF5322)
LLMDOFAF_01562 3.9e-15 M LysM domain
LLMDOFAF_01563 6.6e-122 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
LLMDOFAF_01564 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LLMDOFAF_01565 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
LLMDOFAF_01566 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LLMDOFAF_01567 4.7e-24 L Transposase
LLMDOFAF_01568 6.9e-86 XK27_03610 K Gnat family
LLMDOFAF_01569 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
LLMDOFAF_01570 2.1e-276 pepV 3.5.1.18 E Dipeptidase
LLMDOFAF_01571 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
LLMDOFAF_01572 9.1e-13 V Glucan-binding protein C
LLMDOFAF_01574 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LLMDOFAF_01575 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
LLMDOFAF_01576 8.1e-41 S Protein of unknown function (DUF1697)
LLMDOFAF_01577 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LLMDOFAF_01578 9.4e-66 clcA_2 P chloride
LLMDOFAF_01579 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
LLMDOFAF_01580 1.5e-30 yfeJ 6.3.5.2 F glutamine amidotransferase
LLMDOFAF_01581 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
LLMDOFAF_01582 8e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
LLMDOFAF_01583 4.6e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
LLMDOFAF_01584 1.9e-116 cps4C M biosynthesis protein
LLMDOFAF_01585 9.7e-119 cpsD D COG0489 ATPases involved in chromosome partitioning
LLMDOFAF_01586 2.4e-256 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
LLMDOFAF_01587 2.4e-31 rgpAc GT4 M Domain of unknown function (DUF1972)
LLMDOFAF_01588 3.3e-88 cpsF M Oligosaccharide biosynthesis protein Alg14 like
LLMDOFAF_01589 2e-91 pssE S Glycosyltransferase family 28 C-terminal domain
LLMDOFAF_01590 4.6e-202 GT4 M Glycosyltransferase, group 1 family protein
LLMDOFAF_01591 7.6e-174 rgpB GT2 S Glycosyl transferase family 2
LLMDOFAF_01592 5.8e-202 cps1B GT2,GT4 M Glycosyl transferases group 1
LLMDOFAF_01594 1.1e-183 M Glycosyltransferase, group 2 family protein
LLMDOFAF_01595 2.8e-93 pat 2.3.1.183 M acetyltransferase
LLMDOFAF_01596 7.3e-82 alkD L Dna alkylation repair
LLMDOFAF_01597 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LLMDOFAF_01598 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LLMDOFAF_01599 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
LLMDOFAF_01600 0.0 smc D Required for chromosome condensation and partitioning
LLMDOFAF_01601 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LLMDOFAF_01602 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
LLMDOFAF_01603 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
LLMDOFAF_01605 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
LLMDOFAF_01606 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
LLMDOFAF_01608 2e-86 S ECF-type riboflavin transporter, S component
LLMDOFAF_01609 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
LLMDOFAF_01610 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
LLMDOFAF_01611 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
LLMDOFAF_01612 1.9e-294 yfmM S abc transporter atp-binding protein
LLMDOFAF_01613 3.4e-258 noxE P NADH oxidase
LLMDOFAF_01614 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
LLMDOFAF_01615 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LLMDOFAF_01616 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
LLMDOFAF_01617 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
LLMDOFAF_01618 1.8e-165 ypuA S secreted protein
LLMDOFAF_01619 3.3e-26 L Transposase (IS116 IS110 IS902 family)
LLMDOFAF_01620 4.2e-71 L Transposase (IS116 IS110 IS902 family)
LLMDOFAF_01622 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLMDOFAF_01623 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LLMDOFAF_01624 2.2e-34 nrdH O Glutaredoxin
LLMDOFAF_01625 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LLMDOFAF_01626 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
LLMDOFAF_01627 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
LLMDOFAF_01628 7.9e-39 ptsH G phosphocarrier protein Hpr
LLMDOFAF_01629 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LLMDOFAF_01630 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
LLMDOFAF_01631 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
LLMDOFAF_01632 9.3e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
LLMDOFAF_01633 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
LLMDOFAF_01634 0.0 uup S abc transporter atp-binding protein
LLMDOFAF_01635 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
LLMDOFAF_01636 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LLMDOFAF_01637 8.7e-150 cobQ S glutamine amidotransferase
LLMDOFAF_01638 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
LLMDOFAF_01639 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LLMDOFAF_01640 6e-169 ybbR S Protein conserved in bacteria
LLMDOFAF_01641 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LLMDOFAF_01642 1.7e-70 gtrA S GtrA-like protein
LLMDOFAF_01643 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
LLMDOFAF_01644 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LLMDOFAF_01645 2.3e-14 zupT P Mediates zinc uptake. May also transport other divalent cations
LLMDOFAF_01646 6.4e-29 zupT P transporter
LLMDOFAF_01647 1.6e-207 yurR 1.4.5.1 E oxidoreductase
LLMDOFAF_01648 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LLMDOFAF_01649 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
LLMDOFAF_01650 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
LLMDOFAF_01653 1.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
LLMDOFAF_01654 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
LLMDOFAF_01655 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
LLMDOFAF_01656 1.1e-121 ylfI S tigr01906
LLMDOFAF_01657 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
LLMDOFAF_01658 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
LLMDOFAF_01659 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
LLMDOFAF_01660 1.3e-22 XK27_08085
LLMDOFAF_01661 5.2e-36 L transposase activity
LLMDOFAF_01662 1.6e-131 cbiO P ABC transporter
LLMDOFAF_01663 1.7e-137 P cobalt transport protein
LLMDOFAF_01664 2.7e-177 cbiM P PDGLE domain
LLMDOFAF_01665 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LLMDOFAF_01666 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LLMDOFAF_01667 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
LLMDOFAF_01668 6.6e-78 ureE O enzyme active site formation
LLMDOFAF_01669 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
LLMDOFAF_01670 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
LLMDOFAF_01671 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
LLMDOFAF_01672 6.8e-95 ureI S AmiS/UreI family transporter
LLMDOFAF_01673 1.4e-54 S Domain of unknown function (DUF4173)
LLMDOFAF_01674 3.7e-22 yhaI L Membrane
LLMDOFAF_01675 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LLMDOFAF_01676 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LLMDOFAF_01677 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
LLMDOFAF_01678 1.6e-32 V protein secretion by the type I secretion system
LLMDOFAF_01679 2.5e-161 K sequence-specific DNA binding
LLMDOFAF_01680 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
LLMDOFAF_01681 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LLMDOFAF_01682 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
LLMDOFAF_01683 1.8e-248 trkA P Potassium transporter peripheral membrane component
LLMDOFAF_01684 1.2e-258 trkH P Cation transport protein
LLMDOFAF_01685 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
LLMDOFAF_01686 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
LLMDOFAF_01687 2.3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LLMDOFAF_01688 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LLMDOFAF_01689 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
LLMDOFAF_01690 5.4e-86 ykuL S CBS domain
LLMDOFAF_01691 3.5e-99 XK27_09740 S Phosphoesterase
LLMDOFAF_01692 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LLMDOFAF_01693 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
LLMDOFAF_01694 7.6e-36 yneF S UPF0154 protein
LLMDOFAF_01695 9.6e-92 K transcriptional regulator
LLMDOFAF_01696 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
LLMDOFAF_01699 1.5e-97 ybhL S Belongs to the BI1 family
LLMDOFAF_01700 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
LLMDOFAF_01701 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LLMDOFAF_01702 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
LLMDOFAF_01703 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
LLMDOFAF_01704 5.3e-89 L Integrase core domain protein
LLMDOFAF_01705 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
LLMDOFAF_01706 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LLMDOFAF_01707 9.3e-46 XK27_09675 K -acetyltransferase
LLMDOFAF_01708 3.1e-20 XK27_09675 K -acetyltransferase
LLMDOFAF_01709 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
LLMDOFAF_01710 2.5e-23
LLMDOFAF_01711 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
LLMDOFAF_01712 1e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
LLMDOFAF_01713 7.9e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
LLMDOFAF_01714 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
LLMDOFAF_01715 3.1e-95 ypsA S Belongs to the UPF0398 family
LLMDOFAF_01716 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
LLMDOFAF_01717 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LLMDOFAF_01718 4.6e-260 pepC 3.4.22.40 E aminopeptidase
LLMDOFAF_01719 1.9e-77 yhaI L Membrane
LLMDOFAF_01720 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
LLMDOFAF_01721 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LLMDOFAF_01722 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
LLMDOFAF_01723 2.6e-76 S thiolester hydrolase activity
LLMDOFAF_01725 3.8e-40 K transcriptional
LLMDOFAF_01726 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
LLMDOFAF_01727 3.9e-21 glcR K transcriptional regulator (DeoR family)
LLMDOFAF_01728 2.8e-76 glcR K transcriptional regulator (DeoR family)
LLMDOFAF_01729 4e-34 cof Q phosphatase activity
LLMDOFAF_01730 6e-55 cof Q phosphatase activity
LLMDOFAF_01731 9.3e-86 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
LLMDOFAF_01732 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
LLMDOFAF_01733 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
LLMDOFAF_01734 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
LLMDOFAF_01735 7.3e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
LLMDOFAF_01736 6.8e-56 S TM2 domain
LLMDOFAF_01737 4.7e-43
LLMDOFAF_01740 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LLMDOFAF_01741 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
LLMDOFAF_01742 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
LLMDOFAF_01743 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
LLMDOFAF_01744 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
LLMDOFAF_01745 2.3e-27
LLMDOFAF_01746 7.6e-146 S ABC-2 family transporter protein
LLMDOFAF_01747 4.1e-150 S transport system, permease component
LLMDOFAF_01748 1.8e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LLMDOFAF_01749 4.2e-195 desK 2.7.13.3 T Histidine kinase
LLMDOFAF_01750 7.4e-135 yvfS V ABC-2 type transporter
LLMDOFAF_01751 2.1e-160 XK27_09825 V 'abc transporter, ATP-binding protein
LLMDOFAF_01755 2.3e-213 EGP Major facilitator Superfamily
LLMDOFAF_01756 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
LLMDOFAF_01757 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
LLMDOFAF_01758 3.9e-41 3.6.1.55 F NUDIX domain
LLMDOFAF_01760 3.7e-122 S An automated process has identified a potential problem with this gene model
LLMDOFAF_01761 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
LLMDOFAF_01762 1.6e-14 liaI KT membrane
LLMDOFAF_01763 2.6e-30 liaI KT membrane
LLMDOFAF_01764 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
LLMDOFAF_01765 0.0 V ABC transporter (permease)
LLMDOFAF_01766 5.8e-135 macB2 V ABC transporter, ATP-binding protein
LLMDOFAF_01767 6.2e-166 T Histidine kinase
LLMDOFAF_01768 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
LLMDOFAF_01769 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
LLMDOFAF_01771 3.3e-69 pbuX F xanthine permease
LLMDOFAF_01772 9.2e-119 pbuX F xanthine permease
LLMDOFAF_01773 5.3e-248 norM V Multidrug efflux pump
LLMDOFAF_01774 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LLMDOFAF_01775 7.8e-236 brnQ E Component of the transport system for branched-chain amino acids
LLMDOFAF_01776 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
LLMDOFAF_01777 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
LLMDOFAF_01778 9.6e-26 csbD K CsbD-like
LLMDOFAF_01779 1.5e-245 yfnA E amino acid
LLMDOFAF_01780 6.1e-111 XK27_02070 S nitroreductase
LLMDOFAF_01781 2.1e-154 1.13.11.2 S glyoxalase
LLMDOFAF_01782 3.3e-77 ywnA K Transcriptional regulator
LLMDOFAF_01783 6.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
LLMDOFAF_01784 2.4e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
LLMDOFAF_01785 1.3e-111 drgA C Nitroreductase
LLMDOFAF_01786 2.4e-75 yoaK S Protein of unknown function (DUF1275)
LLMDOFAF_01787 3.1e-161 yvgN C reductase
LLMDOFAF_01788 5.6e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LLMDOFAF_01789 2.4e-09
LLMDOFAF_01790 1.6e-140 S Abortive infection C-terminus
LLMDOFAF_01791 0.0 L DEAD-like helicases superfamily
LLMDOFAF_01792 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
LLMDOFAF_01793 2.7e-285 XK27_07020 S Belongs to the UPF0371 family
LLMDOFAF_01795 1.1e-37 BP1961 P nitric oxide dioxygenase activity
LLMDOFAF_01796 1.6e-53 K response regulator
LLMDOFAF_01797 9.3e-72 S Signal peptide protein, YSIRK family
LLMDOFAF_01798 4.5e-61
LLMDOFAF_01799 5.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LLMDOFAF_01800 1.9e-35
LLMDOFAF_01801 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
LLMDOFAF_01802 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
LLMDOFAF_01803 5.8e-109 MA20_06410 E LysE type translocator
LLMDOFAF_01804 5.6e-08
LLMDOFAF_01805 2.7e-09
LLMDOFAF_01806 0.0 M family 8
LLMDOFAF_01808 1.1e-151 V MatE
LLMDOFAF_01810 1.5e-109 C Fe-S oxidoreductases
LLMDOFAF_01811 1.2e-176 EGP Major Facilitator Superfamily
LLMDOFAF_01812 5.5e-258 I radical SAM domain protein
LLMDOFAF_01814 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
LLMDOFAF_01815 1.4e-150 L Integrase core domain protein
LLMDOFAF_01816 1.8e-87 L transposase activity
LLMDOFAF_01818 1.5e-61
LLMDOFAF_01819 0.0 sbcC L ATPase involved in DNA repair
LLMDOFAF_01820 5.3e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
LLMDOFAF_01821 0.0 lacL 3.2.1.23 G -beta-galactosidase
LLMDOFAF_01822 0.0 lacS G transporter
LLMDOFAF_01823 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
LLMDOFAF_01824 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
LLMDOFAF_01825 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
LLMDOFAF_01826 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LLMDOFAF_01827 1.8e-184 galR K Transcriptional regulator
LLMDOFAF_01828 2.7e-08 L Integrase core domain protein
LLMDOFAF_01829 1.2e-25 L transposition
LLMDOFAF_01830 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
LLMDOFAF_01831 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
LLMDOFAF_01832 2.5e-101 V abc transporter atp-binding protein
LLMDOFAF_01833 4.3e-40 V abc transporter atp-binding protein
LLMDOFAF_01834 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
LLMDOFAF_01835 2.3e-87 L Transposase
LLMDOFAF_01836 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
LLMDOFAF_01837 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
LLMDOFAF_01838 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
LLMDOFAF_01839 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LLMDOFAF_01842 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
LLMDOFAF_01843 5.8e-175 vraS 2.7.13.3 T Histidine kinase
LLMDOFAF_01844 3.7e-120 yvqF KT membrane
LLMDOFAF_01845 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
LLMDOFAF_01846 9e-133 stp 3.1.3.16 T phosphatase
LLMDOFAF_01847 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LLMDOFAF_01848 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LLMDOFAF_01849 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LLMDOFAF_01850 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
LLMDOFAF_01851 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
LLMDOFAF_01852 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
LLMDOFAF_01853 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
LLMDOFAF_01854 2.1e-148 supH S overlaps another CDS with the same product name
LLMDOFAF_01855 8.6e-63 yvoA_1 K Transcriptional
LLMDOFAF_01856 9.8e-121 skfE V abc transporter atp-binding protein
LLMDOFAF_01857 5.6e-133 V ATPase activity
LLMDOFAF_01858 4.3e-172 oppF P Belongs to the ABC transporter superfamily
LLMDOFAF_01859 2.2e-204 oppD P Belongs to the ABC transporter superfamily
LLMDOFAF_01860 4.9e-168 amiD P ABC transporter (Permease
LLMDOFAF_01861 4.2e-278 amiC P ABC transporter (Permease
LLMDOFAF_01862 0.0 amiA E ABC transporter, substrate-binding protein, family 5

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)