ORF_ID e_value Gene_name EC_number CAZy COGs Description
HHILKPEH_00001 1.1e-151 V MatE
HHILKPEH_00003 1.5e-109 C Fe-S oxidoreductases
HHILKPEH_00004 1.2e-176 EGP Major Facilitator Superfamily
HHILKPEH_00005 5.5e-258 I radical SAM domain protein
HHILKPEH_00007 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HHILKPEH_00008 1.4e-150 L Integrase core domain protein
HHILKPEH_00009 1.8e-87 L transposase activity
HHILKPEH_00011 1.5e-61
HHILKPEH_00012 0.0 sbcC L ATPase involved in DNA repair
HHILKPEH_00013 5.3e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HHILKPEH_00014 0.0 lacL 3.2.1.23 G -beta-galactosidase
HHILKPEH_00015 0.0 lacS G transporter
HHILKPEH_00016 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HHILKPEH_00017 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHILKPEH_00018 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HHILKPEH_00019 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHILKPEH_00020 1.8e-184 galR K Transcriptional regulator
HHILKPEH_00021 2.7e-08 L Integrase core domain protein
HHILKPEH_00022 1.2e-25 L transposition
HHILKPEH_00023 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HHILKPEH_00024 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HHILKPEH_00025 2.5e-101 V abc transporter atp-binding protein
HHILKPEH_00026 4.3e-40 V abc transporter atp-binding protein
HHILKPEH_00027 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HHILKPEH_00028 2.3e-87 L Transposase
HHILKPEH_00029 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HHILKPEH_00030 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HHILKPEH_00031 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HHILKPEH_00032 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHILKPEH_00035 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHILKPEH_00036 5.8e-175 vraS 2.7.13.3 T Histidine kinase
HHILKPEH_00037 3.7e-120 yvqF KT membrane
HHILKPEH_00038 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HHILKPEH_00039 9e-133 stp 3.1.3.16 T phosphatase
HHILKPEH_00040 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHILKPEH_00041 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHILKPEH_00042 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHILKPEH_00043 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HHILKPEH_00044 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HHILKPEH_00045 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHILKPEH_00046 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
HHILKPEH_00047 2.1e-148 supH S overlaps another CDS with the same product name
HHILKPEH_00048 8.6e-63 yvoA_1 K Transcriptional
HHILKPEH_00049 9.8e-121 skfE V abc transporter atp-binding protein
HHILKPEH_00050 5.6e-133 V ATPase activity
HHILKPEH_00051 4.3e-172 oppF P Belongs to the ABC transporter superfamily
HHILKPEH_00052 2.2e-204 oppD P Belongs to the ABC transporter superfamily
HHILKPEH_00053 4.9e-168 amiD P ABC transporter (Permease
HHILKPEH_00054 4.2e-278 amiC P ABC transporter (Permease
HHILKPEH_00055 6.3e-293 amiA E ABC transporter, substrate-binding protein, family 5
HHILKPEH_00056 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHILKPEH_00057 1e-33 L Transposase
HHILKPEH_00058 1e-13 rpmH J Ribosomal protein L34
HHILKPEH_00059 2e-186 jag S RNA-binding protein
HHILKPEH_00060 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHILKPEH_00061 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHILKPEH_00062 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
HHILKPEH_00063 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHILKPEH_00064 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHILKPEH_00065 6.7e-81 amiA E transmembrane transport
HHILKPEH_00066 2e-41 amiA E transmembrane transport
HHILKPEH_00067 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
HHILKPEH_00068 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
HHILKPEH_00069 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHILKPEH_00070 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHILKPEH_00071 9.2e-51 S Protein of unknown function (DUF3397)
HHILKPEH_00072 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HHILKPEH_00073 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
HHILKPEH_00074 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
HHILKPEH_00075 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
HHILKPEH_00076 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHILKPEH_00077 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HHILKPEH_00078 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
HHILKPEH_00079 4.3e-77 XK27_09620 S reductase
HHILKPEH_00080 9e-62 XK27_09615 C reductase
HHILKPEH_00081 1e-141 XK27_09615 C reductase
HHILKPEH_00082 3.2e-62 fnt P Formate nitrite transporter
HHILKPEH_00083 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
HHILKPEH_00084 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HHILKPEH_00085 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHILKPEH_00086 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HHILKPEH_00087 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHILKPEH_00088 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHILKPEH_00089 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHILKPEH_00090 2.7e-48 S glycolate biosynthetic process
HHILKPEH_00091 1.5e-64 S phosphatase activity
HHILKPEH_00092 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
HHILKPEH_00095 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHILKPEH_00096 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHILKPEH_00097 8.3e-37 yeeD O sulfur carrier activity
HHILKPEH_00098 2.8e-193 yeeE S Sulphur transport
HHILKPEH_00099 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHILKPEH_00100 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHILKPEH_00101 4.1e-09 S Domain of unknown function (DUF4651)
HHILKPEH_00102 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HHILKPEH_00103 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHILKPEH_00104 1.8e-111 S CAAX amino terminal protease family protein
HHILKPEH_00106 5e-67 V CAAX protease self-immunity
HHILKPEH_00107 1.4e-33 V CAAX protease self-immunity
HHILKPEH_00108 8.8e-27 lanR K sequence-specific DNA binding
HHILKPEH_00109 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHILKPEH_00110 5.9e-177 ytxK 2.1.1.72 L DNA methylase
HHILKPEH_00111 2e-12 comGF U Putative Competence protein ComGF
HHILKPEH_00112 1.5e-71 comGF U Competence protein ComGF
HHILKPEH_00113 1.4e-15 NU Type II secretory pathway pseudopilin
HHILKPEH_00114 1.8e-57 cglD NU Competence protein
HHILKPEH_00115 8.5e-43 comGC U Required for transformation and DNA binding
HHILKPEH_00116 1.1e-156 cglB U protein transport across the cell outer membrane
HHILKPEH_00117 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHILKPEH_00118 1e-68 S cog cog4699
HHILKPEH_00119 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHILKPEH_00120 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHILKPEH_00121 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHILKPEH_00122 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHILKPEH_00123 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HHILKPEH_00124 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
HHILKPEH_00125 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HHILKPEH_00126 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HHILKPEH_00127 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHILKPEH_00128 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHILKPEH_00129 1e-134 parB K Belongs to the ParB family
HHILKPEH_00130 4.5e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HHILKPEH_00131 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHILKPEH_00132 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
HHILKPEH_00136 0.0 XK27_10405 S Bacterial membrane protein YfhO
HHILKPEH_00137 6.7e-306 ybiT S abc transporter atp-binding protein
HHILKPEH_00138 1.1e-153 yvjA S membrane
HHILKPEH_00139 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HHILKPEH_00140 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HHILKPEH_00141 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHILKPEH_00142 1.6e-45 yaaA S S4 domain protein YaaA
HHILKPEH_00143 4.8e-235 ymfF S Peptidase M16
HHILKPEH_00144 1.1e-242 ymfH S Peptidase M16
HHILKPEH_00145 3.7e-138 ymfM S sequence-specific DNA binding
HHILKPEH_00146 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHILKPEH_00147 7.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHILKPEH_00148 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHILKPEH_00149 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHILKPEH_00150 3.1e-93 lytE M LysM domain protein
HHILKPEH_00151 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
HHILKPEH_00152 0.0 S Bacterial membrane protein, YfhO
HHILKPEH_00153 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHILKPEH_00154 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHILKPEH_00155 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HHILKPEH_00156 3.9e-70 rplI J binds to the 23S rRNA
HHILKPEH_00157 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HHILKPEH_00158 8.2e-48 veg S Biofilm formation stimulator VEG
HHILKPEH_00159 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHILKPEH_00160 2.7e-08
HHILKPEH_00161 4.8e-55 ypaA M Membrane
HHILKPEH_00162 6.4e-96 XK27_06935 K transcriptional regulator
HHILKPEH_00163 3.9e-161 XK27_06930 V domain protein
HHILKPEH_00164 1.8e-88 S Putative adhesin
HHILKPEH_00165 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
HHILKPEH_00167 1.7e-23 K negative regulation of transcription, DNA-templated
HHILKPEH_00168 4e-19 K negative regulation of transcription, DNA-templated
HHILKPEH_00169 3.4e-13 nudL L hydrolase
HHILKPEH_00170 7.2e-95 nudL L hydrolase
HHILKPEH_00171 4.9e-12 K CsbD-like
HHILKPEH_00172 1.1e-71 M Protein conserved in bacteria
HHILKPEH_00173 1.8e-23 S Small integral membrane protein
HHILKPEH_00174 3.1e-101
HHILKPEH_00175 3.7e-27 S Membrane
HHILKPEH_00177 2.7e-95 S Hydrophobic domain protein
HHILKPEH_00178 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
HHILKPEH_00180 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHILKPEH_00181 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HHILKPEH_00182 9.2e-36 metE 2.1.1.14 E Methionine synthase
HHILKPEH_00183 7.6e-64 metE 2.1.1.14 E Methionine synthase
HHILKPEH_00184 5.7e-52 metE 2.1.1.14 E Methionine synthase
HHILKPEH_00185 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
HHILKPEH_00187 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HHILKPEH_00188 9.9e-169 XK27_01785 S cog cog1284
HHILKPEH_00189 1.8e-147 yaaA S Belongs to the UPF0246 family
HHILKPEH_00190 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHILKPEH_00191 2.6e-91 XK27_10930 K acetyltransferase
HHILKPEH_00192 7.5e-14
HHILKPEH_00193 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HHILKPEH_00194 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
HHILKPEH_00195 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
HHILKPEH_00196 1.4e-29 S Domain of unknown function (DUF1912)
HHILKPEH_00197 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HHILKPEH_00198 5.2e-251 mmuP E amino acid
HHILKPEH_00199 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HHILKPEH_00200 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHILKPEH_00201 9.7e-22
HHILKPEH_00202 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHILKPEH_00203 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHILKPEH_00204 1.7e-218 mvaS 2.3.3.10 I synthase
HHILKPEH_00205 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HHILKPEH_00206 1e-25 K hmm pf08876
HHILKPEH_00207 1.5e-118 yqfA K protein, Hemolysin III
HHILKPEH_00208 1.2e-22 S Protein of unknown function (DUF3114)
HHILKPEH_00209 8.6e-167 S Protein of unknown function (DUF3114)
HHILKPEH_00210 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHILKPEH_00211 8.9e-57 S hydrolase activity, acting on ester bonds
HHILKPEH_00212 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHILKPEH_00213 4.9e-21 XK27_13030
HHILKPEH_00214 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HHILKPEH_00215 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HHILKPEH_00217 2.1e-50 U protein secretion
HHILKPEH_00218 3.5e-07 U protein secretion
HHILKPEH_00220 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHILKPEH_00221 2.5e-21
HHILKPEH_00222 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HHILKPEH_00223 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHILKPEH_00224 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHILKPEH_00225 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
HHILKPEH_00226 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HHILKPEH_00227 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HHILKPEH_00228 4.6e-105 GBS0088 J protein conserved in bacteria
HHILKPEH_00229 6.1e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHILKPEH_00230 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HHILKPEH_00231 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
HHILKPEH_00232 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHILKPEH_00233 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHILKPEH_00234 8.7e-114 S VIT family
HHILKPEH_00235 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
HHILKPEH_00236 1.1e-22
HHILKPEH_00237 8e-28 XK27_00085 K Transcriptional
HHILKPEH_00238 2.4e-197 yceA S Belongs to the UPF0176 family
HHILKPEH_00239 5.4e-122 sagI S ABC-2 type transporter
HHILKPEH_00240 2.8e-168 V ABC transporter
HHILKPEH_00241 7.1e-214 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HHILKPEH_00242 2.5e-132 rr02 KT response regulator
HHILKPEH_00243 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HHILKPEH_00244 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHILKPEH_00245 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHILKPEH_00246 0.0 lmrA V abc transporter atp-binding protein
HHILKPEH_00247 0.0 mdlB V abc transporter atp-binding protein
HHILKPEH_00249 0.0 M the current gene model (or a revised gene model) may contain a
HHILKPEH_00250 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHILKPEH_00251 1e-78 yueI S Protein of unknown function (DUF1694)
HHILKPEH_00252 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HHILKPEH_00253 6.6e-101 yyaQ V Protein conserved in bacteria
HHILKPEH_00254 2.8e-28 yyaQ S YjbR
HHILKPEH_00255 4.4e-183 ccpA K Catabolite control protein A
HHILKPEH_00256 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HHILKPEH_00257 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HHILKPEH_00258 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHILKPEH_00259 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHILKPEH_00260 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHILKPEH_00261 2.6e-33 secG U Preprotein translocase subunit SecG
HHILKPEH_00262 9.5e-74 mdtG EGP Major facilitator Superfamily
HHILKPEH_00263 6e-133 mdtG EGP Major facilitator Superfamily
HHILKPEH_00264 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHILKPEH_00265 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHILKPEH_00266 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHILKPEH_00267 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HHILKPEH_00268 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHILKPEH_00269 6.8e-53 licT K transcriptional antiterminator
HHILKPEH_00270 9.2e-43 licT K transcriptional antiterminator
HHILKPEH_00272 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHILKPEH_00273 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HHILKPEH_00274 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHILKPEH_00275 2.1e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHILKPEH_00276 7.5e-23 I Alpha/beta hydrolase family
HHILKPEH_00277 1.5e-35 yugF I carboxylic ester hydrolase activity
HHILKPEH_00278 2.2e-45 K sequence-specific DNA binding
HHILKPEH_00279 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HHILKPEH_00280 1.5e-07
HHILKPEH_00281 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HHILKPEH_00282 1.1e-78 feoA P FeoA domain protein
HHILKPEH_00283 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
HHILKPEH_00284 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HHILKPEH_00285 1.3e-34 ykuJ S protein conserved in bacteria
HHILKPEH_00286 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHILKPEH_00287 0.0 clpE O Belongs to the ClpA ClpB family
HHILKPEH_00288 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HHILKPEH_00289 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
HHILKPEH_00290 2.4e-66 S oxidoreductase
HHILKPEH_00291 1.5e-50 S oxidoreductase
HHILKPEH_00292 6.8e-234 murN 2.3.2.10, 2.3.2.16 V FemAB family
HHILKPEH_00293 1.7e-63 M Pfam SNARE associated Golgi protein
HHILKPEH_00294 1.5e-30 S Domain of Unknown Function with PDB structure (DUF3862)
HHILKPEH_00295 1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
HHILKPEH_00298 6.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
HHILKPEH_00301 4.8e-16 S Protein of unknown function (DUF2969)
HHILKPEH_00302 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HHILKPEH_00303 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHILKPEH_00304 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHILKPEH_00305 1.2e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHILKPEH_00306 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
HHILKPEH_00307 3.1e-172 yxaM EGP Major facilitator Superfamily
HHILKPEH_00308 8.8e-83 adk 2.7.4.3 F topology modulation protein
HHILKPEH_00309 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHILKPEH_00310 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHILKPEH_00311 1.7e-35 XK27_09805 S MORN repeat protein
HHILKPEH_00312 0.0 XK27_09800 I Acyltransferase
HHILKPEH_00313 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHILKPEH_00314 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HHILKPEH_00315 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHILKPEH_00316 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
HHILKPEH_00317 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHILKPEH_00318 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHILKPEH_00319 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHILKPEH_00320 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHILKPEH_00321 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHILKPEH_00322 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHILKPEH_00323 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HHILKPEH_00324 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHILKPEH_00325 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHILKPEH_00326 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHILKPEH_00327 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHILKPEH_00328 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHILKPEH_00329 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHILKPEH_00330 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHILKPEH_00331 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHILKPEH_00332 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHILKPEH_00333 2.5e-23 rpmD J ribosomal protein l30
HHILKPEH_00334 4.4e-58 rplO J binds to the 23S rRNA
HHILKPEH_00335 2.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHILKPEH_00336 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHILKPEH_00337 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHILKPEH_00338 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HHILKPEH_00339 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHILKPEH_00340 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHILKPEH_00341 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHILKPEH_00342 3.3e-62 rplQ J ribosomal protein l17
HHILKPEH_00343 1.8e-111 L PFAM Integrase, catalytic core
HHILKPEH_00344 3.3e-09 L PFAM Integrase, catalytic core
HHILKPEH_00345 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
HHILKPEH_00346 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
HHILKPEH_00347 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
HHILKPEH_00349 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
HHILKPEH_00350 4.2e-72 L PFAM Integrase, catalytic core
HHILKPEH_00352 9.8e-71 L Phage integrase family
HHILKPEH_00353 2.4e-23 S phage tail tape measure protein
HHILKPEH_00354 7.1e-130 S EcsC protein family
HHILKPEH_00355 2e-20 S phage tail
HHILKPEH_00356 1.8e-127 tnp L Transposase
HHILKPEH_00358 3.3e-95 ywlG S Belongs to the UPF0340 family
HHILKPEH_00359 1.2e-85 treR K trehalose operon
HHILKPEH_00360 5.8e-21 treR K DNA-binding transcription factor activity
HHILKPEH_00361 1.4e-54 treB 2.7.1.201 G PTS System
HHILKPEH_00362 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HHILKPEH_00363 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HHILKPEH_00364 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HHILKPEH_00365 4e-226 pepO 3.4.24.71 O Peptidase family M13
HHILKPEH_00366 1.7e-133 pepO 3.4.24.71 O Peptidase family M13
HHILKPEH_00367 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
HHILKPEH_00368 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHILKPEH_00369 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHILKPEH_00370 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
HHILKPEH_00371 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHILKPEH_00372 9.2e-278 thrC 4.2.3.1 E Threonine synthase
HHILKPEH_00373 3.2e-226 norN V Mate efflux family protein
HHILKPEH_00374 1.8e-57 asp S cog cog1302
HHILKPEH_00375 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
HHILKPEH_00376 0.0 yfmR S abc transporter atp-binding protein
HHILKPEH_00377 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHILKPEH_00378 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHILKPEH_00379 3.6e-74 XK27_08360 S EDD domain protein, DegV family
HHILKPEH_00380 6.4e-61 XK27_08360 S EDD domain protein, DegV family
HHILKPEH_00381 2.6e-64 WQ51_03320 S cog cog4835
HHILKPEH_00382 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHILKPEH_00383 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HHILKPEH_00384 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HHILKPEH_00385 6.4e-29 2.3.1.128 K acetyltransferase
HHILKPEH_00386 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HHILKPEH_00387 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HHILKPEH_00388 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHILKPEH_00389 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HHILKPEH_00391 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHILKPEH_00392 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HHILKPEH_00393 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
HHILKPEH_00394 5.1e-145 fruA 2.7.1.202 G phosphotransferase system
HHILKPEH_00395 8e-98 fruA 2.7.1.202 G phosphotransferase system
HHILKPEH_00396 2.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HHILKPEH_00397 5.6e-114 fruR K transcriptional
HHILKPEH_00398 1.8e-84 L Transposase
HHILKPEH_00399 1.1e-202 rny D Endoribonuclease that initiates mRNA decay
HHILKPEH_00400 1.4e-65 tnp L Transposase
HHILKPEH_00401 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHILKPEH_00402 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HHILKPEH_00403 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHILKPEH_00404 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HHILKPEH_00405 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHILKPEH_00406 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHILKPEH_00407 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHILKPEH_00408 1.6e-126 IQ reductase
HHILKPEH_00409 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HHILKPEH_00410 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HHILKPEH_00411 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHILKPEH_00412 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHILKPEH_00413 4e-72 marR K Transcriptional regulator, MarR family
HHILKPEH_00414 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HHILKPEH_00415 1.9e-115 S Haloacid dehalogenase-like hydrolase
HHILKPEH_00416 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HHILKPEH_00417 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
HHILKPEH_00418 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHILKPEH_00419 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
HHILKPEH_00420 1.3e-101 ygaC J Belongs to the UPF0374 family
HHILKPEH_00421 6.4e-108 S Domain of unknown function (DUF1803)
HHILKPEH_00422 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
HHILKPEH_00429 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HHILKPEH_00430 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHILKPEH_00431 0.0 dnaE 2.7.7.7 L DNA polymerase
HHILKPEH_00432 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
HHILKPEH_00433 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHILKPEH_00434 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHILKPEH_00435 2.5e-43 ysdA L Membrane
HHILKPEH_00436 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HHILKPEH_00437 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HHILKPEH_00438 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHILKPEH_00439 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HHILKPEH_00441 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHILKPEH_00442 2.1e-84 ypmS S Protein conserved in bacteria
HHILKPEH_00443 1.3e-143 ypmR E lipolytic protein G-D-S-L family
HHILKPEH_00444 1e-148 DegV S DegV family
HHILKPEH_00445 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
HHILKPEH_00446 3.7e-73 argR K Regulates arginine biosynthesis genes
HHILKPEH_00447 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HHILKPEH_00448 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHILKPEH_00449 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
HHILKPEH_00450 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHILKPEH_00453 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHILKPEH_00454 2.9e-125 dnaD
HHILKPEH_00455 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HHILKPEH_00456 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHILKPEH_00457 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HHILKPEH_00458 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHILKPEH_00459 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHILKPEH_00460 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HHILKPEH_00461 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHILKPEH_00462 5.4e-197 L transposase, IS4 family
HHILKPEH_00463 5.6e-240 rodA D Belongs to the SEDS family
HHILKPEH_00464 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
HHILKPEH_00465 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HHILKPEH_00466 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHILKPEH_00467 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HHILKPEH_00468 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHILKPEH_00469 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HHILKPEH_00470 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHILKPEH_00471 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HHILKPEH_00472 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HHILKPEH_00473 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHILKPEH_00475 4.5e-32 L Integrase core domain protein
HHILKPEH_00476 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHILKPEH_00477 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHILKPEH_00478 4.6e-238 dltB M Membrane protein involved in D-alanine export
HHILKPEH_00479 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHILKPEH_00480 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
HHILKPEH_00481 0.0 XK27_10035 V abc transporter atp-binding protein
HHILKPEH_00482 0.0 yfiB1 V abc transporter atp-binding protein
HHILKPEH_00483 6e-106 pvaA M lytic transglycosylase activity
HHILKPEH_00484 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
HHILKPEH_00485 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHILKPEH_00486 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHILKPEH_00487 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHILKPEH_00488 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHILKPEH_00489 4.5e-111 tdk 2.7.1.21 F thymidine kinase
HHILKPEH_00490 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HHILKPEH_00491 2.4e-155 gst O Glutathione S-transferase
HHILKPEH_00492 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HHILKPEH_00493 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHILKPEH_00494 2e-45 rpmE2 J 50S ribosomal protein L31
HHILKPEH_00495 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
HHILKPEH_00496 1.3e-10
HHILKPEH_00497 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHILKPEH_00498 1.8e-135 divIVA D Cell division protein DivIVA
HHILKPEH_00499 4.2e-144 ylmH T S4 RNA-binding domain
HHILKPEH_00500 2e-34 yggT D integral membrane protein
HHILKPEH_00501 1.4e-96 sepF D cell septum assembly
HHILKPEH_00502 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHILKPEH_00503 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHILKPEH_00504 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHILKPEH_00505 6.7e-172 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHILKPEH_00506 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHILKPEH_00507 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHILKPEH_00509 0.0 typA T GTP-binding protein TypA
HHILKPEH_00510 2.2e-179 glk 2.7.1.2 G Glucokinase
HHILKPEH_00511 8.4e-28 yqgQ S protein conserved in bacteria
HHILKPEH_00512 1.1e-80 perR P Belongs to the Fur family
HHILKPEH_00513 3.2e-92 dps P Belongs to the Dps family
HHILKPEH_00514 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HHILKPEH_00515 4.8e-196 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HHILKPEH_00516 1.2e-165 L integrase core domain
HHILKPEH_00517 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHILKPEH_00518 3.5e-143 pts33BCA G pts system
HHILKPEH_00519 5.8e-71 pts33BCA G pts system
HHILKPEH_00520 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
HHILKPEH_00521 1.8e-254 cycA E permease
HHILKPEH_00522 4.5e-39 ynzC S UPF0291 protein
HHILKPEH_00523 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HHILKPEH_00524 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HHILKPEH_00525 6.1e-63 S membrane
HHILKPEH_00526 1.5e-59
HHILKPEH_00527 7.5e-26
HHILKPEH_00528 1.8e-53
HHILKPEH_00529 1.9e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHILKPEH_00530 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
HHILKPEH_00531 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HHILKPEH_00532 4.9e-106 mur1 NU mannosyl-glycoprotein
HHILKPEH_00533 1.1e-53 glnB K Belongs to the P(II) protein family
HHILKPEH_00534 2.6e-233 amt P Ammonium Transporter
HHILKPEH_00535 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHILKPEH_00536 9.5e-55 yabA L Involved in initiation control of chromosome replication
HHILKPEH_00537 1.2e-135 yaaT S stage 0 sporulation protein
HHILKPEH_00538 6.4e-162 holB 2.7.7.7 L dna polymerase iii
HHILKPEH_00539 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHILKPEH_00540 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHILKPEH_00541 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHILKPEH_00542 2.8e-230 ftsW D Belongs to the SEDS family
HHILKPEH_00543 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HHILKPEH_00544 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHILKPEH_00545 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHILKPEH_00546 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHILKPEH_00547 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHILKPEH_00548 3.3e-78 atpF C ATP synthase F(0) sector subunit b
HHILKPEH_00549 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HHILKPEH_00550 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHILKPEH_00551 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHILKPEH_00552 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHILKPEH_00553 6.6e-147 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHILKPEH_00554 8.9e-14 coiA 3.6.4.12 S Competence protein
HHILKPEH_00555 2.2e-15 T peptidase
HHILKPEH_00556 5.5e-153 rarD S Transporter
HHILKPEH_00557 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHILKPEH_00558 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HHILKPEH_00559 1e-114 papP P ABC transporter (Permease
HHILKPEH_00560 3.5e-115 P ABC transporter (Permease
HHILKPEH_00561 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HHILKPEH_00562 1.1e-155 cjaA ET ABC transporter substrate-binding protein
HHILKPEH_00566 1e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHILKPEH_00567 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
HHILKPEH_00568 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHILKPEH_00569 1.9e-201 yjbB G Permeases of the major facilitator superfamily
HHILKPEH_00570 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HHILKPEH_00571 2.3e-99 thiT S Thiamine transporter
HHILKPEH_00572 1.9e-62 yjqA S Bacterial PH domain
HHILKPEH_00573 2.3e-154 corA P CorA-like protein
HHILKPEH_00574 2.4e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHILKPEH_00575 1e-41 yazA L endonuclease containing a URI domain
HHILKPEH_00576 7.1e-141 yabB 2.1.1.223 L Methyltransferase
HHILKPEH_00577 1.8e-140 nodB3 G deacetylase
HHILKPEH_00578 1.7e-142 plsC 2.3.1.51 I Acyltransferase
HHILKPEH_00579 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HHILKPEH_00580 0.0 comEC S Competence protein ComEC
HHILKPEH_00581 1.5e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHILKPEH_00582 1.1e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HHILKPEH_00583 3e-232 ytoI K transcriptional regulator containing CBS domains
HHILKPEH_00584 1.9e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HHILKPEH_00585 5.8e-161 rbn E Belongs to the UPF0761 family
HHILKPEH_00586 2.2e-85 ccl S cog cog4708
HHILKPEH_00587 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHILKPEH_00588 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHILKPEH_00589 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
HHILKPEH_00590 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
HHILKPEH_00591 2.1e-74 S QueT transporter
HHILKPEH_00592 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HHILKPEH_00593 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HHILKPEH_00594 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HHILKPEH_00595 4.1e-37 ylqC L Belongs to the UPF0109 family
HHILKPEH_00596 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHILKPEH_00597 0.0 ydaO E amino acid
HHILKPEH_00598 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
HHILKPEH_00599 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HHILKPEH_00600 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HHILKPEH_00601 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHILKPEH_00602 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHILKPEH_00603 7.8e-171 murB 1.3.1.98 M cell wall formation
HHILKPEH_00604 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHILKPEH_00605 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
HHILKPEH_00606 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
HHILKPEH_00607 2.3e-206 potD P spermidine putrescine ABC transporter
HHILKPEH_00608 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
HHILKPEH_00609 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
HHILKPEH_00610 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
HHILKPEH_00611 2.1e-25 GK ROK family
HHILKPEH_00612 4.6e-58 GK ROK family
HHILKPEH_00613 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HHILKPEH_00614 3.9e-104 wecD M Acetyltransferase GNAT family
HHILKPEH_00615 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHILKPEH_00616 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HHILKPEH_00617 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
HHILKPEH_00619 7.7e-56 lrgA S Effector of murein hydrolase LrgA
HHILKPEH_00620 2.2e-117 lrgB M effector of murein hydrolase
HHILKPEH_00621 2.6e-109 3.1.3.18 S IA, variant 1
HHILKPEH_00622 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHILKPEH_00623 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHILKPEH_00624 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
HHILKPEH_00625 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HHILKPEH_00626 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHILKPEH_00627 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHILKPEH_00628 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
HHILKPEH_00630 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
HHILKPEH_00631 4.7e-51 ycaO O OsmC-like protein
HHILKPEH_00632 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
HHILKPEH_00635 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHILKPEH_00637 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHILKPEH_00638 1.1e-16 XK27_00735
HHILKPEH_00639 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
HHILKPEH_00640 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HHILKPEH_00641 2.4e-33 S CAAX amino terminal protease family protein
HHILKPEH_00642 2.5e-56 V CAAX protease self-immunity
HHILKPEH_00643 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHILKPEH_00644 2.9e-84 mutT 3.6.1.55 F Nudix family
HHILKPEH_00645 7.5e-144 ET Belongs to the bacterial solute-binding protein 3 family
HHILKPEH_00646 6.5e-137 ET ABC transporter
HHILKPEH_00647 1.6e-202 arcT 2.6.1.1 E Aminotransferase
HHILKPEH_00648 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
HHILKPEH_00649 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HHILKPEH_00650 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHILKPEH_00651 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHILKPEH_00652 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HHILKPEH_00653 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HHILKPEH_00654 5.3e-237 S Predicted membrane protein (DUF2142)
HHILKPEH_00655 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HHILKPEH_00656 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
HHILKPEH_00657 9.3e-186 S Glycosyltransferase like family 2
HHILKPEH_00658 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
HHILKPEH_00659 6.9e-130 arnC M group 2 family protein
HHILKPEH_00660 4.6e-42 S Uncharacterized conserved protein (DUF2304)
HHILKPEH_00661 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
HHILKPEH_00662 1.8e-228 rgpA GT4 M Domain of unknown function (DUF1972)
HHILKPEH_00663 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
HHILKPEH_00664 2.1e-143 rgpC GM Transport permease protein
HHILKPEH_00665 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HHILKPEH_00666 2e-305 GT4 M transferase activity, transferring glycosyl groups
HHILKPEH_00667 0.0 rgpF M Rhamnan synthesis protein F
HHILKPEH_00668 1.7e-268 M Psort location CytoplasmicMembrane, score
HHILKPEH_00669 1.2e-115 radC E Belongs to the UPF0758 family
HHILKPEH_00670 7.2e-132 puuD T peptidase C26
HHILKPEH_00671 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHILKPEH_00672 3.1e-59 XK27_04120 S Putative amino acid metabolism
HHILKPEH_00673 2.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
HHILKPEH_00674 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHILKPEH_00675 1.5e-103 yjbK S Adenylate cyclase
HHILKPEH_00676 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HHILKPEH_00677 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHILKPEH_00678 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HHILKPEH_00679 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HHILKPEH_00680 1.4e-66 L transposition
HHILKPEH_00681 2.6e-166 cpsY K Transcriptional regulator
HHILKPEH_00682 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHILKPEH_00683 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
HHILKPEH_00684 2.4e-105 artQ P ABC transporter (Permease
HHILKPEH_00685 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
HHILKPEH_00686 1.1e-158 aatB ET ABC transporter substrate-binding protein
HHILKPEH_00687 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHILKPEH_00688 2.1e-07
HHILKPEH_00689 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
HHILKPEH_00690 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
HHILKPEH_00691 1.1e-19 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
HHILKPEH_00692 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HHILKPEH_00693 2e-126 gntR1 K transcriptional
HHILKPEH_00694 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHILKPEH_00695 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHILKPEH_00696 2.4e-87 niaX
HHILKPEH_00697 6e-91 niaR S small molecule binding protein (contains 3H domain)
HHILKPEH_00698 9.6e-129 K DNA-binding helix-turn-helix protein
HHILKPEH_00699 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHILKPEH_00700 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHILKPEH_00701 8.2e-168 GK ROK family
HHILKPEH_00702 8.3e-159 dprA LU DNA protecting protein DprA
HHILKPEH_00703 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHILKPEH_00704 3.6e-154 S TraX protein
HHILKPEH_00705 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHILKPEH_00706 1.3e-249 T PhoQ Sensor
HHILKPEH_00707 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHILKPEH_00708 1.1e-152 XK27_05470 E Methionine synthase
HHILKPEH_00709 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HHILKPEH_00710 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHILKPEH_00711 1.8e-51 IQ Acetoin reductase
HHILKPEH_00712 3.9e-19 IQ Acetoin reductase
HHILKPEH_00713 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHILKPEH_00714 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HHILKPEH_00717 1.3e-212 pqqE C radical SAM domain protein
HHILKPEH_00718 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
HHILKPEH_00719 6.6e-61 EGP Major facilitator Superfamily
HHILKPEH_00720 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HHILKPEH_00721 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HHILKPEH_00722 3.7e-151 K Helix-turn-helix XRE-family like proteins
HHILKPEH_00723 9.2e-284 V ABC transporter transmembrane region
HHILKPEH_00724 2.9e-31 yozG K Transcriptional regulator
HHILKPEH_00727 2.1e-185 V Abi-like protein
HHILKPEH_00729 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHILKPEH_00730 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHILKPEH_00731 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHILKPEH_00732 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHILKPEH_00733 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HHILKPEH_00734 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHILKPEH_00736 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHILKPEH_00737 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HHILKPEH_00738 0.0 scrA 2.7.1.211 G pts system
HHILKPEH_00739 5.4e-291 scrB 3.2.1.26 GH32 G invertase
HHILKPEH_00740 7.5e-180 scrR K Transcriptional
HHILKPEH_00741 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHILKPEH_00742 3.4e-62 yqhY S protein conserved in bacteria
HHILKPEH_00743 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHILKPEH_00744 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
HHILKPEH_00745 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HHILKPEH_00747 8e-44 V 'abc transporter, ATP-binding protein
HHILKPEH_00748 3.8e-58 V 'abc transporter, ATP-binding protein
HHILKPEH_00751 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HHILKPEH_00752 2e-169 corA P COG0598 Mg2 and Co2 transporters
HHILKPEH_00753 3.1e-124 XK27_01040 S Pfam PF06570
HHILKPEH_00755 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHILKPEH_00756 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHILKPEH_00757 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HHILKPEH_00758 3.6e-41 XK27_05745
HHILKPEH_00759 2.5e-230 mutY L A G-specific adenine glycosylase
HHILKPEH_00764 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHILKPEH_00765 4.4e-123 comFC S Competence protein
HHILKPEH_00766 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HHILKPEH_00767 6.3e-111 yvyE 3.4.13.9 S YigZ family
HHILKPEH_00768 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HHILKPEH_00769 3.3e-43 acuB S IMP dehydrogenase activity
HHILKPEH_00770 1.1e-69 acuB S IMP dehydrogenase activity
HHILKPEH_00771 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HHILKPEH_00772 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HHILKPEH_00773 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
HHILKPEH_00774 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HHILKPEH_00775 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HHILKPEH_00776 7.1e-46 ylbG S UPF0298 protein
HHILKPEH_00777 3.4e-74 ylbF S Belongs to the UPF0342 family
HHILKPEH_00778 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHILKPEH_00779 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHILKPEH_00780 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HHILKPEH_00782 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HHILKPEH_00783 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
HHILKPEH_00784 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HHILKPEH_00785 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HHILKPEH_00786 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHILKPEH_00787 3.2e-214 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HHILKPEH_00788 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
HHILKPEH_00789 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
HHILKPEH_00790 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHILKPEH_00791 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHILKPEH_00792 1.4e-41 ylxQ J ribosomal protein
HHILKPEH_00793 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HHILKPEH_00794 3.1e-212 nusA K Participates in both transcription termination and antitermination
HHILKPEH_00795 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HHILKPEH_00796 2.5e-220 brpA K Transcriptional
HHILKPEH_00797 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
HHILKPEH_00798 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HHILKPEH_00799 1.9e-248 pbuO S permease
HHILKPEH_00800 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HHILKPEH_00801 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HHILKPEH_00802 1.3e-174 manL 2.7.1.191 G pts system
HHILKPEH_00803 7e-118 manM G pts system
HHILKPEH_00804 1.9e-169 manN G PTS system mannose fructose sorbose family IID component
HHILKPEH_00805 6.5e-63 manO S protein conserved in bacteria
HHILKPEH_00806 1.5e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHILKPEH_00807 1.2e-34
HHILKPEH_00809 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HHILKPEH_00810 5.2e-167 dnaI L Primosomal protein DnaI
HHILKPEH_00811 6.5e-218 dnaB L Replication initiation and membrane attachment
HHILKPEH_00812 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHILKPEH_00813 2.8e-282 T PhoQ Sensor
HHILKPEH_00814 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHILKPEH_00815 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
HHILKPEH_00816 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HHILKPEH_00817 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
HHILKPEH_00818 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
HHILKPEH_00819 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
HHILKPEH_00820 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHILKPEH_00821 1.2e-149 cbiQ P cobalt transport
HHILKPEH_00822 0.0 ykoD P abc transporter atp-binding protein
HHILKPEH_00823 9.4e-95 S UPF0397 protein
HHILKPEH_00824 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HHILKPEH_00825 2.7e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HHILKPEH_00826 3e-98 metI P ABC transporter (Permease
HHILKPEH_00827 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHILKPEH_00828 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HHILKPEH_00829 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HHILKPEH_00830 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HHILKPEH_00831 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
HHILKPEH_00832 1.8e-153 ET amino acid transport
HHILKPEH_00833 3.8e-205 EGP Transmembrane secretion effector
HHILKPEH_00834 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
HHILKPEH_00835 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHILKPEH_00836 3.3e-118 ET amino acid transport
HHILKPEH_00837 0.0 3.6.3.8 P cation transport ATPase
HHILKPEH_00838 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HHILKPEH_00840 3e-44 ymbI L transposase activity
HHILKPEH_00841 4e-22 L Belongs to the 'phage' integrase family
HHILKPEH_00842 1.4e-66 S tRNA_anti-like
HHILKPEH_00843 2e-103
HHILKPEH_00845 5e-12
HHILKPEH_00847 2e-296 S DNA primase
HHILKPEH_00848 3e-164 KL Phage plasmid primase P4 family
HHILKPEH_00849 6.9e-22
HHILKPEH_00850 9.2e-13
HHILKPEH_00855 1.3e-17 K Cro/C1-type HTH DNA-binding domain
HHILKPEH_00857 1.1e-220 sip L Belongs to the 'phage' integrase family
HHILKPEH_00859 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HHILKPEH_00860 7.3e-166 metF 1.5.1.20 E reductase
HHILKPEH_00861 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HHILKPEH_00862 1.7e-94 panT S ECF transporter, substrate-specific component
HHILKPEH_00863 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHILKPEH_00864 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HHILKPEH_00865 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HHILKPEH_00866 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHILKPEH_00867 2.8e-40 T PhoQ Sensor
HHILKPEH_00868 1.7e-43 T PhoQ Sensor
HHILKPEH_00869 5.8e-79 T PhoQ Sensor
HHILKPEH_00870 2.2e-61 rlpA M LysM domain protein
HHILKPEH_00871 8e-191 phoH T phosphate starvation-inducible protein PhoH
HHILKPEH_00875 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHILKPEH_00876 1.8e-167 K transcriptional regulator (lysR family)
HHILKPEH_00877 1.4e-186 coiA 3.6.4.12 S Competence protein
HHILKPEH_00878 0.0 pepF E oligoendopeptidase F
HHILKPEH_00879 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
HHILKPEH_00880 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HHILKPEH_00881 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHILKPEH_00882 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HHILKPEH_00883 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HHILKPEH_00884 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
HHILKPEH_00885 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
HHILKPEH_00886 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHILKPEH_00887 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HHILKPEH_00888 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHILKPEH_00889 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HHILKPEH_00890 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HHILKPEH_00891 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HHILKPEH_00892 8.5e-142 yxkH G deacetylase
HHILKPEH_00893 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HHILKPEH_00894 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHILKPEH_00895 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
HHILKPEH_00896 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HHILKPEH_00897 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHILKPEH_00899 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHILKPEH_00901 6.5e-63 KT phosphorelay signal transduction system
HHILKPEH_00902 1.9e-80 S Protein of unknown function (DUF3021)
HHILKPEH_00903 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHILKPEH_00904 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HHILKPEH_00905 8.2e-70 argR K Regulates arginine biosynthesis genes
HHILKPEH_00906 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HHILKPEH_00907 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHILKPEH_00908 9.2e-141 1.1.1.169 H Ketopantoate reductase
HHILKPEH_00909 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHILKPEH_00910 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHILKPEH_00911 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
HHILKPEH_00912 2.3e-161 S CHAP domain
HHILKPEH_00919 5.3e-11
HHILKPEH_00925 1.3e-140 mreC M Involved in formation and maintenance of cell shape
HHILKPEH_00926 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HHILKPEH_00927 8.9e-102 usp 3.5.1.28 CBM50 S CHAP domain
HHILKPEH_00928 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHILKPEH_00929 2.5e-26
HHILKPEH_00930 5.9e-219 araT 2.6.1.1 E Aminotransferase
HHILKPEH_00931 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
HHILKPEH_00932 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHILKPEH_00933 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHILKPEH_00934 5.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HHILKPEH_00935 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHILKPEH_00936 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHILKPEH_00937 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HHILKPEH_00938 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHILKPEH_00939 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HHILKPEH_00940 1e-90 L transposase activity
HHILKPEH_00941 1.3e-87 S Fusaric acid resistance protein-like
HHILKPEH_00942 8.5e-63 glnR K Transcriptional regulator
HHILKPEH_00943 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
HHILKPEH_00944 2.7e-40 pscB M CHAP domain protein
HHILKPEH_00945 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHILKPEH_00946 2.5e-33 ykzG S Belongs to the UPF0356 family
HHILKPEH_00947 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HHILKPEH_00948 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HHILKPEH_00949 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHILKPEH_00950 1.3e-117 azlC E AzlC protein
HHILKPEH_00951 2e-47 azlD E branched-chain amino acid
HHILKPEH_00952 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHILKPEH_00953 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHILKPEH_00954 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHILKPEH_00955 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HHILKPEH_00956 1e-93 cvpA S toxin biosynthetic process
HHILKPEH_00957 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHILKPEH_00958 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHILKPEH_00961 3.2e-110
HHILKPEH_00962 1.3e-56 S CD20-like family
HHILKPEH_00963 6e-11
HHILKPEH_00964 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HHILKPEH_00965 2.3e-133 ecsA V abc transporter atp-binding protein
HHILKPEH_00966 2.7e-183 ecsB U ABC transporter
HHILKPEH_00967 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
HHILKPEH_00968 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHILKPEH_00970 7.7e-227 ytfP S Flavoprotein
HHILKPEH_00971 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HHILKPEH_00972 7.4e-64 XK27_02560 S cog cog2151
HHILKPEH_00973 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
HHILKPEH_00974 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
HHILKPEH_00975 1.4e-81 K transcriptional regulator, MerR family
HHILKPEH_00976 5.1e-47 L transposase activity
HHILKPEH_00977 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHILKPEH_00978 3.9e-26
HHILKPEH_00979 0.0 ctpE P E1-E2 ATPase
HHILKPEH_00980 1.4e-54
HHILKPEH_00981 4.2e-44 yrzB S Belongs to the UPF0473 family
HHILKPEH_00982 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHILKPEH_00983 2.8e-44 yrzL S Belongs to the UPF0297 family
HHILKPEH_00984 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HHILKPEH_00985 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HHILKPEH_00987 3.5e-216 int L Belongs to the 'phage' integrase family
HHILKPEH_00988 1.9e-18 S Domain of unknown function (DUF3173)
HHILKPEH_00989 1.4e-107 L Replication initiation factor
HHILKPEH_00990 1e-36 L Replication initiation factor
HHILKPEH_00991 1.7e-90 K sequence-specific DNA binding
HHILKPEH_00992 3.9e-287 V ABC transporter transmembrane region
HHILKPEH_00993 3.4e-191 C Radical SAM
HHILKPEH_00995 1.4e-127 Z012_04635 K sequence-specific DNA binding
HHILKPEH_00996 2.1e-280 V ABC transporter
HHILKPEH_00997 0.0 KLT serine threonine protein kinase
HHILKPEH_00998 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HHILKPEH_01000 6.4e-104 V ABC transporter (Permease
HHILKPEH_01001 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHILKPEH_01002 1.6e-10
HHILKPEH_01003 9e-98 K Transcriptional regulator, TetR family
HHILKPEH_01004 1.8e-159 czcD P cation diffusion facilitator family transporter
HHILKPEH_01005 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HHILKPEH_01006 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HHILKPEH_01007 6e-08 S Hydrolases of the alpha beta superfamily
HHILKPEH_01008 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
HHILKPEH_01009 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
HHILKPEH_01012 1.2e-143 2.4.2.3 F Phosphorylase superfamily
HHILKPEH_01013 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HHILKPEH_01014 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
HHILKPEH_01015 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
HHILKPEH_01017 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HHILKPEH_01018 3.7e-190
HHILKPEH_01019 8.1e-90 FNV0100 F Belongs to the Nudix hydrolase family
HHILKPEH_01020 3.5e-28 3.4.13.21 I Protein conserved in bacteria
HHILKPEH_01022 4.3e-118 S TraX protein
HHILKPEH_01023 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HHILKPEH_01024 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HHILKPEH_01025 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHILKPEH_01026 6e-188 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHILKPEH_01027 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHILKPEH_01028 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
HHILKPEH_01029 1.1e-204 csm1 S CRISPR-associated protein Csm1 family
HHILKPEH_01030 1.2e-210 csm1 S CRISPR-associated protein Csm1 family
HHILKPEH_01031 2.5e-62 csm2 L Csm2 Type III-A
HHILKPEH_01032 1.6e-117 csm3 L RAMP superfamily
HHILKPEH_01033 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
HHILKPEH_01034 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
HHILKPEH_01036 9.5e-32 csm6 S Psort location Cytoplasmic, score
HHILKPEH_01037 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHILKPEH_01038 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHILKPEH_01039 1.6e-266 dtpT E transporter
HHILKPEH_01040 1.4e-62 yecS P ABC transporter (Permease
HHILKPEH_01041 2.3e-20 yecS P amino acid transport
HHILKPEH_01043 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HHILKPEH_01044 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
HHILKPEH_01045 4e-99 yfiF3 K sequence-specific DNA binding
HHILKPEH_01046 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHILKPEH_01047 1.8e-240 agcS E (Alanine) symporter
HHILKPEH_01048 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HHILKPEH_01049 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
HHILKPEH_01050 1.8e-59 Q phosphatase activity
HHILKPEH_01051 9.3e-62 S haloacid dehalogenase-like hydrolase
HHILKPEH_01052 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHILKPEH_01053 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HHILKPEH_01054 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
HHILKPEH_01055 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
HHILKPEH_01056 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHILKPEH_01057 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HHILKPEH_01058 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHILKPEH_01059 1.9e-43 yktA S Belongs to the UPF0223 family
HHILKPEH_01060 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HHILKPEH_01061 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HHILKPEH_01062 3.3e-158 pstS P phosphate
HHILKPEH_01063 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HHILKPEH_01064 1.2e-155 pstA P phosphate transport system permease
HHILKPEH_01065 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHILKPEH_01066 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHILKPEH_01067 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
HHILKPEH_01068 0.0 pepN 3.4.11.2 E aminopeptidase
HHILKPEH_01069 8.3e-196 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HHILKPEH_01070 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
HHILKPEH_01073 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HHILKPEH_01074 1.2e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HHILKPEH_01075 2.3e-23 L Transposase
HHILKPEH_01076 4.6e-25 tatA U protein secretion
HHILKPEH_01077 9e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHILKPEH_01078 7.2e-303 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HHILKPEH_01079 8.7e-234 ycdB P peroxidase
HHILKPEH_01080 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
HHILKPEH_01081 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
HHILKPEH_01082 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
HHILKPEH_01083 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHILKPEH_01084 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHILKPEH_01085 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HHILKPEH_01086 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HHILKPEH_01087 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HHILKPEH_01088 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HHILKPEH_01089 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HHILKPEH_01090 8.6e-187 3.5.1.28 M GBS Bsp-like repeat
HHILKPEH_01091 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HHILKPEH_01092 6.4e-11 3.5.1.28 NU amidase activity
HHILKPEH_01093 0.0 lpdA 1.8.1.4 C Dehydrogenase
HHILKPEH_01094 1.1e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHILKPEH_01095 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHILKPEH_01096 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HHILKPEH_01097 1.1e-37 P membrane protein (DUF2207)
HHILKPEH_01098 4.4e-66 S the current gene model (or a revised gene model) may contain a frame shift
HHILKPEH_01099 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHILKPEH_01100 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHILKPEH_01101 3e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHILKPEH_01102 3.8e-17 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
HHILKPEH_01103 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
HHILKPEH_01104 1.3e-125 3.4.16.4 M Belongs to the peptidase S11 family
HHILKPEH_01105 1.3e-159 rssA S Phospholipase, patatin family
HHILKPEH_01106 6.1e-79 estA E GDSL-like protein
HHILKPEH_01107 2.6e-15 estA E Lysophospholipase L1 and related esterases
HHILKPEH_01108 2e-294 S unusual protein kinase
HHILKPEH_01109 4.9e-39 S granule-associated protein
HHILKPEH_01110 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHILKPEH_01111 3.5e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHILKPEH_01112 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHILKPEH_01113 1.3e-199 S hmm pf01594
HHILKPEH_01114 3.9e-61 G Belongs to the phosphoglycerate mutase family
HHILKPEH_01115 3.5e-29 G Belongs to the phosphoglycerate mutase family
HHILKPEH_01116 7.6e-70 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
HHILKPEH_01117 1.4e-96 V VanZ like family
HHILKPEH_01118 0.0
HHILKPEH_01120 1.5e-35 K sequence-specific DNA binding
HHILKPEH_01121 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HHILKPEH_01122 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHILKPEH_01123 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHILKPEH_01124 1.8e-31 K helix-turn-helix
HHILKPEH_01125 3.4e-155 degV S DegV family
HHILKPEH_01126 3.5e-91 yacP S RNA-binding protein containing a PIN domain
HHILKPEH_01127 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHILKPEH_01130 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHILKPEH_01131 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHILKPEH_01132 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
HHILKPEH_01133 6.9e-144 S SseB protein N-terminal domain
HHILKPEH_01134 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HHILKPEH_01135 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHILKPEH_01136 9e-08
HHILKPEH_01137 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HHILKPEH_01138 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HHILKPEH_01139 3.1e-81 ypmB S Protein conserved in bacteria
HHILKPEH_01140 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HHILKPEH_01141 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HHILKPEH_01142 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
HHILKPEH_01143 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
HHILKPEH_01144 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HHILKPEH_01145 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HHILKPEH_01146 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HHILKPEH_01147 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHILKPEH_01148 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHILKPEH_01149 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HHILKPEH_01150 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HHILKPEH_01151 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
HHILKPEH_01152 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
HHILKPEH_01153 2.1e-30 rpsT J rRNA binding
HHILKPEH_01154 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
HHILKPEH_01155 3.1e-10 L thioesterase
HHILKPEH_01156 7.8e-143 S Macro domain protein
HHILKPEH_01157 4.8e-51 trxA O Belongs to the thioredoxin family
HHILKPEH_01158 2.5e-26 yccU S CoA-binding protein
HHILKPEH_01159 1.4e-144 tatD L Hydrolase, tatd
HHILKPEH_01160 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHILKPEH_01161 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHILKPEH_01163 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHILKPEH_01164 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HHILKPEH_01165 1.8e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
HHILKPEH_01166 6.9e-173 rmuC S RmuC domain protein
HHILKPEH_01167 1.8e-178 cbf S 3'-5' exoribonuclease yhaM
HHILKPEH_01168 1.1e-142 purR 2.4.2.7 F operon repressor
HHILKPEH_01169 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHILKPEH_01170 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHILKPEH_01171 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHILKPEH_01172 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHILKPEH_01173 7.4e-35 yozE S Belongs to the UPF0346 family
HHILKPEH_01174 5.3e-161 cvfB S Protein conserved in bacteria
HHILKPEH_01175 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHILKPEH_01176 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HHILKPEH_01177 2.9e-120 sptS 2.7.13.3 T Histidine kinase
HHILKPEH_01178 1.6e-44 K Acetyltransferase (GNAT) family
HHILKPEH_01179 0.0 lmrA2 V abc transporter atp-binding protein
HHILKPEH_01180 0.0 lmrA1 V abc transporter atp-binding protein
HHILKPEH_01181 1.9e-77 K DNA-binding transcription factor activity
HHILKPEH_01182 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HHILKPEH_01183 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HHILKPEH_01184 2.1e-204 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HHILKPEH_01185 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HHILKPEH_01186 1.6e-24 U response to pH
HHILKPEH_01187 1.1e-29 yyzM S Protein conserved in bacteria
HHILKPEH_01188 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHILKPEH_01189 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHILKPEH_01190 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHILKPEH_01191 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HHILKPEH_01192 2.7e-61 divIC D Septum formation initiator
HHILKPEH_01194 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HHILKPEH_01195 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHILKPEH_01196 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHILKPEH_01197 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHILKPEH_01198 2.4e-164 L Transposase
HHILKPEH_01199 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
HHILKPEH_01200 4.3e-109 capA M Bacterial capsule synthesis protein
HHILKPEH_01201 1.5e-55 capA M Bacterial capsule synthesis protein
HHILKPEH_01202 3.6e-39 gcvR T UPF0237 protein
HHILKPEH_01203 1.7e-243 XK27_08635 S UPF0210 protein
HHILKPEH_01204 2.4e-135 ais G Phosphoglycerate mutase
HHILKPEH_01205 2.1e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HHILKPEH_01206 1.3e-102 acmA 3.2.1.17 NU amidase activity
HHILKPEH_01207 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHILKPEH_01208 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHILKPEH_01209 7.5e-298 dnaK O Heat shock 70 kDa protein
HHILKPEH_01210 3.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHILKPEH_01211 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHILKPEH_01212 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HHILKPEH_01213 3.8e-31 hmpT S membrane
HHILKPEH_01218 1.8e-167 fhuR K transcriptional regulator (lysR family)
HHILKPEH_01219 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHILKPEH_01220 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHILKPEH_01221 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHILKPEH_01222 4.9e-227 pyrP F uracil Permease
HHILKPEH_01223 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HHILKPEH_01224 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HHILKPEH_01225 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HHILKPEH_01226 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
HHILKPEH_01227 8.7e-259 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHILKPEH_01228 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HHILKPEH_01229 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHILKPEH_01230 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HHILKPEH_01231 1.4e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HHILKPEH_01232 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HHILKPEH_01233 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHILKPEH_01234 3.2e-74 copY K Copper transport repressor, CopY TcrY family
HHILKPEH_01235 0.0 copA 3.6.3.54 P P-type ATPase
HHILKPEH_01236 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
HHILKPEH_01237 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HHILKPEH_01238 1e-190 L Transposase
HHILKPEH_01239 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
HHILKPEH_01240 8.9e-206 potD P spermidine putrescine ABC transporter
HHILKPEH_01241 3.1e-268 clcA P Chloride transporter, ClC family
HHILKPEH_01242 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
HHILKPEH_01243 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HHILKPEH_01244 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HHILKPEH_01245 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
HHILKPEH_01246 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HHILKPEH_01247 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HHILKPEH_01248 7.7e-20 D nuclear chromosome segregation
HHILKPEH_01249 7.4e-138 yejC S cyclic nucleotide-binding protein
HHILKPEH_01250 1.2e-163 rapZ S Displays ATPase and GTPase activities
HHILKPEH_01251 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HHILKPEH_01252 8.7e-162 whiA K May be required for sporulation
HHILKPEH_01253 2.8e-90 pepD E Dipeptidase
HHILKPEH_01254 5.8e-41 pepD E dipeptidase activity
HHILKPEH_01255 5.4e-32 cspD K Cold shock protein domain
HHILKPEH_01256 9.4e-43 K Cold-Shock Protein
HHILKPEH_01257 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HHILKPEH_01258 6.9e-206 ylbM S Belongs to the UPF0348 family
HHILKPEH_01259 2e-140 yqeM Q Methyltransferase domain protein
HHILKPEH_01260 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHILKPEH_01261 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HHILKPEH_01262 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHILKPEH_01263 3.5e-49 yhbY J RNA-binding protein
HHILKPEH_01264 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HHILKPEH_01265 1.8e-98 yqeG S hydrolase of the HAD superfamily
HHILKPEH_01266 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HHILKPEH_01267 5.8e-24
HHILKPEH_01268 3.5e-13
HHILKPEH_01269 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHILKPEH_01270 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHILKPEH_01271 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHILKPEH_01272 1.3e-251 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHILKPEH_01273 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHILKPEH_01274 1.6e-154 hlpA M Belongs to the NlpA lipoprotein family
HHILKPEH_01275 6.8e-101 pncA Q isochorismatase
HHILKPEH_01276 4.7e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HHILKPEH_01277 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HHILKPEH_01278 2.4e-75 XK27_03180 T universal stress protein
HHILKPEH_01281 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HHILKPEH_01282 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HHILKPEH_01283 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HHILKPEH_01284 0.0 yjcE P NhaP-type Na H and K H antiporters
HHILKPEH_01286 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
HHILKPEH_01287 1.3e-184 yhcC S radical SAM protein
HHILKPEH_01288 2.2e-196 ylbL T Belongs to the peptidase S16 family
HHILKPEH_01289 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHILKPEH_01290 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
HHILKPEH_01291 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHILKPEH_01292 1.9e-09 S Protein of unknown function (DUF4059)
HHILKPEH_01293 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
HHILKPEH_01294 4.7e-163 yxeN P ABC transporter (Permease
HHILKPEH_01295 1.2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HHILKPEH_01297 1.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHILKPEH_01298 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HHILKPEH_01299 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
HHILKPEH_01300 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHILKPEH_01301 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
HHILKPEH_01302 2.9e-87 D nuclear chromosome segregation
HHILKPEH_01303 1.5e-127 ybbM S transport system, permease component
HHILKPEH_01304 1.2e-117 ybbL S abc transporter atp-binding protein
HHILKPEH_01305 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HHILKPEH_01306 4.6e-140 cppA E CppA N-terminal
HHILKPEH_01307 5e-44 V CAAX protease self-immunity
HHILKPEH_01308 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HHILKPEH_01309 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HHILKPEH_01312 3e-47 spiA K sequence-specific DNA binding
HHILKPEH_01313 2.9e-28 blpT
HHILKPEH_01314 6.7e-98 blpT
HHILKPEH_01321 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
HHILKPEH_01325 7.4e-135 agrA KT phosphorelay signal transduction system
HHILKPEH_01326 3.4e-239 blpH 2.7.13.3 T protein histidine kinase activity
HHILKPEH_01328 7.3e-237 mesE M Transport protein ComB
HHILKPEH_01329 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HHILKPEH_01330 0.0 mdlB V abc transporter atp-binding protein
HHILKPEH_01331 9.1e-303 mdlA V abc transporter atp-binding protein
HHILKPEH_01333 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
HHILKPEH_01334 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HHILKPEH_01335 3.6e-70 yutD J protein conserved in bacteria
HHILKPEH_01336 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHILKPEH_01338 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHILKPEH_01339 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHILKPEH_01340 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HHILKPEH_01341 4.3e-47 ftsL D cell division protein FtsL
HHILKPEH_01342 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHILKPEH_01343 1.6e-65
HHILKPEH_01344 7.4e-27
HHILKPEH_01345 2.6e-30
HHILKPEH_01347 9.7e-32 yhaI J Protein of unknown function (DUF805)
HHILKPEH_01348 1.3e-08 D nuclear chromosome segregation
HHILKPEH_01349 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHILKPEH_01350 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHILKPEH_01351 6.2e-288 XK27_00765
HHILKPEH_01352 1.4e-133 ecsA_2 V abc transporter atp-binding protein
HHILKPEH_01353 2.5e-47 S Protein of unknown function (DUF554)
HHILKPEH_01354 8.5e-32 S Protein of unknown function (DUF554)
HHILKPEH_01355 1.6e-11 S Protein of unknown function (DUF554)
HHILKPEH_01356 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HHILKPEH_01357 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HHILKPEH_01358 2.6e-121 liaI S membrane
HHILKPEH_01359 5.2e-75 XK27_02470 K LytTr DNA-binding domain
HHILKPEH_01360 3.6e-66 KT response to antibiotic
HHILKPEH_01361 2.6e-80 yebC M Membrane
HHILKPEH_01362 2.9e-18 yebC M Membrane
HHILKPEH_01363 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
HHILKPEH_01364 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HHILKPEH_01366 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
HHILKPEH_01367 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
HHILKPEH_01368 3.7e-157 glcU U Glucose uptake
HHILKPEH_01369 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
HHILKPEH_01370 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
HHILKPEH_01371 2.2e-101 XK27_10720 D peptidase activity
HHILKPEH_01372 9.2e-297 adcA P Belongs to the bacterial solute-binding protein 9 family
HHILKPEH_01373 1.7e-08
HHILKPEH_01375 1.2e-172 yeiH S Membrane
HHILKPEH_01376 5.1e-117 mur1 NU muramidase
HHILKPEH_01377 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
HHILKPEH_01378 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HHILKPEH_01380 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HHILKPEH_01381 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHILKPEH_01382 5.5e-83 S Putative small multi-drug export protein
HHILKPEH_01383 1.8e-75 ctsR K Belongs to the CtsR family
HHILKPEH_01384 0.0 clpC O Belongs to the ClpA ClpB family
HHILKPEH_01385 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHILKPEH_01386 1.7e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHILKPEH_01387 3.5e-97 S reductase
HHILKPEH_01388 2.6e-55 badR K DNA-binding transcription factor activity
HHILKPEH_01389 1.9e-36 XK27_02060 S Transglycosylase associated protein
HHILKPEH_01390 2.3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HHILKPEH_01391 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHILKPEH_01396 1.9e-07
HHILKPEH_01399 2.6e-10
HHILKPEH_01400 2.4e-178 L transposase, IS4 family
HHILKPEH_01401 3e-13 mesE M Transport protein ComB
HHILKPEH_01402 0.0 P Belongs to the ABC transporter superfamily
HHILKPEH_01403 1.8e-141 dppC P N-terminal TM domain of oligopeptide transport permease C
HHILKPEH_01404 2.8e-188 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHILKPEH_01405 0.0 ddpA E ABC transporter substrate-binding protein
HHILKPEH_01407 1.9e-57 L Transposase
HHILKPEH_01408 1e-110 L Integrase core domain protein
HHILKPEH_01409 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
HHILKPEH_01410 1.4e-40 tatD L Hydrolase, tatd
HHILKPEH_01411 3.8e-45 oppF P Belongs to the ABC transporter superfamily
HHILKPEH_01412 1e-23 oppF P Belongs to the ABC transporter superfamily
HHILKPEH_01413 4.1e-158 L COG2801 Transposase and inactivated derivatives
HHILKPEH_01414 8.1e-45 L Transposase
HHILKPEH_01415 2.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HHILKPEH_01416 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HHILKPEH_01417 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HHILKPEH_01418 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HHILKPEH_01419 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHILKPEH_01420 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHILKPEH_01421 8.2e-28 ytrF V efflux transmembrane transporter activity
HHILKPEH_01422 3.1e-31 V efflux transmembrane transporter activity
HHILKPEH_01423 3.6e-35 V efflux transmembrane transporter activity
HHILKPEH_01424 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
HHILKPEH_01425 1.1e-183 M Glycosyltransferase, group 2 family protein
HHILKPEH_01427 5.8e-202 cps1B GT2,GT4 M Glycosyl transferases group 1
HHILKPEH_01428 7.6e-174 rgpB GT2 S Glycosyl transferase family 2
HHILKPEH_01429 4.6e-202 GT4 M Glycosyltransferase, group 1 family protein
HHILKPEH_01430 2e-91 pssE S Glycosyltransferase family 28 C-terminal domain
HHILKPEH_01431 3.3e-88 cpsF M Oligosaccharide biosynthesis protein Alg14 like
HHILKPEH_01432 2.4e-31 rgpAc GT4 M Domain of unknown function (DUF1972)
HHILKPEH_01433 2.4e-256 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HHILKPEH_01434 9.7e-119 cpsD D COG0489 ATPases involved in chromosome partitioning
HHILKPEH_01435 1.9e-116 cps4C M biosynthesis protein
HHILKPEH_01436 4.6e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HHILKPEH_01437 8e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HHILKPEH_01438 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HHILKPEH_01439 1.5e-30 yfeJ 6.3.5.2 F glutamine amidotransferase
HHILKPEH_01440 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
HHILKPEH_01441 9.4e-66 clcA_2 P chloride
HHILKPEH_01442 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHILKPEH_01443 8.1e-41 S Protein of unknown function (DUF1697)
HHILKPEH_01444 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHILKPEH_01445 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHILKPEH_01447 6.1e-22 V Glucan-binding protein C
HHILKPEH_01448 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
HHILKPEH_01449 2.1e-276 pepV 3.5.1.18 E Dipeptidase
HHILKPEH_01450 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HHILKPEH_01451 6.9e-86 XK27_03610 K Gnat family
HHILKPEH_01452 4.7e-24 L Transposase
HHILKPEH_01453 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHILKPEH_01454 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HHILKPEH_01455 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHILKPEH_01456 6.6e-122 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HHILKPEH_01457 3.9e-15 M LysM domain
HHILKPEH_01458 2.9e-90 ebsA S Family of unknown function (DUF5322)
HHILKPEH_01459 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHILKPEH_01460 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHILKPEH_01461 3.7e-224 G COG0457 FOG TPR repeat
HHILKPEH_01462 6.2e-176 yubA S permease
HHILKPEH_01463 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HHILKPEH_01464 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HHILKPEH_01465 2.5e-124 ftsE D cell division ATP-binding protein FtsE
HHILKPEH_01466 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHILKPEH_01467 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHILKPEH_01468 1.1e-180 yjjH S Calcineurin-like phosphoesterase
HHILKPEH_01469 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HHILKPEH_01470 0.0 pacL 3.6.3.8 P cation transport ATPase
HHILKPEH_01471 2.6e-67 ywiB S Domain of unknown function (DUF1934)
HHILKPEH_01472 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
HHILKPEH_01473 1.2e-146 yidA S hydrolases of the HAD superfamily
HHILKPEH_01474 1.8e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HHILKPEH_01475 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HHILKPEH_01476 1.5e-247 vicK 2.7.13.3 T Histidine kinase
HHILKPEH_01477 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHILKPEH_01478 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HHILKPEH_01479 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HHILKPEH_01480 5.9e-118 gltJ P ABC transporter (Permease
HHILKPEH_01481 1.7e-111 tcyB_2 P ABC transporter (permease)
HHILKPEH_01482 2.4e-124 endA F DNA RNA non-specific endonuclease
HHILKPEH_01483 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
HHILKPEH_01484 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHILKPEH_01486 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHILKPEH_01487 2.2e-21 G Domain of unknown function (DUF4832)
HHILKPEH_01488 8.4e-53 G Domain of unknown function (DUF4832)
HHILKPEH_01489 1.5e-211 cotH M CotH kinase protein
HHILKPEH_01490 2.3e-49 pelG S Putative exopolysaccharide Exporter (EPS-E)
HHILKPEH_01491 3.8e-199 pelG M Putative exopolysaccharide Exporter (EPS-E)
HHILKPEH_01492 4.3e-277 pelF GT4 M Domain of unknown function (DUF3492)
HHILKPEH_01493 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HHILKPEH_01494 2.2e-168
HHILKPEH_01495 0.0 5.1.3.2 GM Psort location CytoplasmicMembrane, score
HHILKPEH_01496 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHILKPEH_01497 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHILKPEH_01498 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHILKPEH_01499 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HHILKPEH_01500 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHILKPEH_01501 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
HHILKPEH_01504 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHILKPEH_01505 3.2e-220 XK27_05110 P chloride
HHILKPEH_01506 5.1e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HHILKPEH_01507 6.4e-282 clcA P Chloride transporter, ClC family
HHILKPEH_01508 2.3e-75 fld C Flavodoxin
HHILKPEH_01509 5.5e-14 XK27_08880
HHILKPEH_01510 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
HHILKPEH_01511 9.2e-152 estA CE1 S Putative esterase
HHILKPEH_01512 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHILKPEH_01513 1.2e-135 XK27_08845 S abc transporter atp-binding protein
HHILKPEH_01514 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HHILKPEH_01515 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
HHILKPEH_01516 3.2e-17 S Domain of unknown function (DUF4649)
HHILKPEH_01518 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
HHILKPEH_01519 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
HHILKPEH_01522 2.4e-214 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHILKPEH_01523 1.9e-225 nodC 2.4.1.212 GT2 M Chitin synthase
HHILKPEH_01524 0.0 copB 3.6.3.4 P P-type ATPase
HHILKPEH_01525 1.4e-92 3.6.4.12 K Divergent AAA domain protein
HHILKPEH_01526 5.9e-24 3.6.4.12
HHILKPEH_01527 7.7e-112 EGP Major facilitator Superfamily
HHILKPEH_01528 4.7e-56 EGP Major facilitator Superfamily
HHILKPEH_01529 6.5e-50 M YSIRK type signal peptide
HHILKPEH_01530 3e-92 S MucBP domain
HHILKPEH_01531 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HHILKPEH_01532 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHILKPEH_01533 3e-246 cps1C S Polysaccharide biosynthesis protein
HHILKPEH_01534 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HHILKPEH_01535 1.6e-18 L Integrase core domain
HHILKPEH_01536 2.2e-51 devA 3.6.3.25 V abc transporter atp-binding protein
HHILKPEH_01537 2e-25 WQ51_00785
HHILKPEH_01538 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHILKPEH_01539 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
HHILKPEH_01540 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HHILKPEH_01541 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HHILKPEH_01542 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HHILKPEH_01543 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHILKPEH_01544 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HHILKPEH_01545 3.2e-53 yheA S Belongs to the UPF0342 family
HHILKPEH_01546 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HHILKPEH_01547 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHILKPEH_01548 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHILKPEH_01549 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
HHILKPEH_01550 2.6e-253 msrR K Transcriptional regulator
HHILKPEH_01551 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
HHILKPEH_01552 2.4e-203 I acyl-CoA dehydrogenase
HHILKPEH_01553 3.5e-97 mip S hydroperoxide reductase activity
HHILKPEH_01554 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHILKPEH_01555 8.9e-20
HHILKPEH_01556 1.2e-45
HHILKPEH_01557 1e-31 K Cro/C1-type HTH DNA-binding domain
HHILKPEH_01558 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HHILKPEH_01559 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
HHILKPEH_01560 4.4e-93
HHILKPEH_01561 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HHILKPEH_01562 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHILKPEH_01563 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HHILKPEH_01564 2.3e-198 S CRISPR-associated protein Csn2 subfamily St
HHILKPEH_01565 1.3e-148 ycgQ S TIGR03943 family
HHILKPEH_01566 1.7e-157 XK27_03015 S permease
HHILKPEH_01568 0.0 yhgF K Transcriptional accessory protein
HHILKPEH_01569 9.9e-42 pspC KT PspC domain
HHILKPEH_01570 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHILKPEH_01571 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHILKPEH_01573 5.5e-69 ytxH S General stress protein
HHILKPEH_01575 4.4e-177 yegQ O Peptidase U32
HHILKPEH_01576 3.4e-252 yegQ O Peptidase U32
HHILKPEH_01577 1.5e-89 bioY S biotin synthase
HHILKPEH_01579 1.1e-33 XK27_12190 S protein conserved in bacteria
HHILKPEH_01580 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
HHILKPEH_01581 1.9e-12
HHILKPEH_01582 7.7e-238 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HHILKPEH_01583 4.2e-117
HHILKPEH_01584 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HHILKPEH_01585 1e-163 M LysM domain
HHILKPEH_01586 7.6e-16
HHILKPEH_01587 2.3e-175 S hydrolase
HHILKPEH_01588 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HHILKPEH_01589 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHILKPEH_01590 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HHILKPEH_01591 2.7e-27 P Hemerythrin HHE cation binding domain protein
HHILKPEH_01592 1.6e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHILKPEH_01593 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
HHILKPEH_01594 9.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
HHILKPEH_01595 8.7e-45 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHILKPEH_01596 7.6e-71 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHILKPEH_01597 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HHILKPEH_01598 1.2e-216 S Bacteriophage abortive infection AbiH
HHILKPEH_01600 2.8e-221 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
HHILKPEH_01601 2.2e-105
HHILKPEH_01602 1e-136 S Protein conserved in bacteria
HHILKPEH_01603 6.6e-306 hsdM 2.1.1.72 V type I restriction-modification system
HHILKPEH_01604 5.9e-22 S PD-(D/E)XK nuclease family transposase
HHILKPEH_01605 1e-36 spd F DNA RNA non-specific endonuclease
HHILKPEH_01606 9.9e-90 spd F DNA RNA non-specific endonuclease
HHILKPEH_01607 9e-93 lemA S LemA family
HHILKPEH_01608 6.4e-133 htpX O Belongs to the peptidase M48B family
HHILKPEH_01609 1.8e-73 S Psort location CytoplasmicMembrane, score
HHILKPEH_01610 6.2e-56 S Domain of unknown function (DUF4430)
HHILKPEH_01611 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HHILKPEH_01612 1.9e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HHILKPEH_01613 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HHILKPEH_01614 4.7e-115 hrtB V MacB-like periplasmic core domain
HHILKPEH_01615 2.8e-93 pat 2.3.1.183 M acetyltransferase
HHILKPEH_01616 7.3e-82 alkD L Dna alkylation repair
HHILKPEH_01617 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHILKPEH_01618 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHILKPEH_01619 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHILKPEH_01620 0.0 smc D Required for chromosome condensation and partitioning
HHILKPEH_01621 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHILKPEH_01622 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHILKPEH_01623 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHILKPEH_01625 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HHILKPEH_01626 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHILKPEH_01628 2e-86 S ECF-type riboflavin transporter, S component
HHILKPEH_01629 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HHILKPEH_01630 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HHILKPEH_01631 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
HHILKPEH_01632 1.9e-294 yfmM S abc transporter atp-binding protein
HHILKPEH_01633 3.4e-258 noxE P NADH oxidase
HHILKPEH_01634 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHILKPEH_01635 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHILKPEH_01636 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HHILKPEH_01637 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
HHILKPEH_01638 1.8e-165 ypuA S secreted protein
HHILKPEH_01639 3.3e-26 L Transposase (IS116 IS110 IS902 family)
HHILKPEH_01640 4.2e-71 L Transposase (IS116 IS110 IS902 family)
HHILKPEH_01642 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHILKPEH_01643 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHILKPEH_01644 2.2e-34 nrdH O Glutaredoxin
HHILKPEH_01645 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHILKPEH_01646 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
HHILKPEH_01647 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
HHILKPEH_01648 7.9e-39 ptsH G phosphocarrier protein Hpr
HHILKPEH_01649 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHILKPEH_01650 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HHILKPEH_01651 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HHILKPEH_01652 9.3e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
HHILKPEH_01653 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HHILKPEH_01654 0.0 uup S abc transporter atp-binding protein
HHILKPEH_01655 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
HHILKPEH_01656 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHILKPEH_01657 8.7e-150 cobQ S glutamine amidotransferase
HHILKPEH_01658 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HHILKPEH_01659 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHILKPEH_01660 6e-169 ybbR S Protein conserved in bacteria
HHILKPEH_01661 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHILKPEH_01662 1.7e-70 gtrA S GtrA-like protein
HHILKPEH_01663 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HHILKPEH_01664 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHILKPEH_01665 2.3e-14 zupT P Mediates zinc uptake. May also transport other divalent cations
HHILKPEH_01666 6.4e-29 zupT P transporter
HHILKPEH_01667 1.6e-207 yurR 1.4.5.1 E oxidoreductase
HHILKPEH_01668 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHILKPEH_01669 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HHILKPEH_01670 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHILKPEH_01673 1.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HHILKPEH_01674 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
HHILKPEH_01675 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHILKPEH_01676 1.1e-121 ylfI S tigr01906
HHILKPEH_01677 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HHILKPEH_01678 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HHILKPEH_01679 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HHILKPEH_01680 1.3e-22 XK27_08085
HHILKPEH_01681 1.6e-131 cbiO P ABC transporter
HHILKPEH_01682 1.7e-137 P cobalt transport protein
HHILKPEH_01683 2.7e-177 cbiM P PDGLE domain
HHILKPEH_01684 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HHILKPEH_01685 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HHILKPEH_01686 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HHILKPEH_01687 6.6e-78 ureE O enzyme active site formation
HHILKPEH_01688 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HHILKPEH_01689 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HHILKPEH_01690 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HHILKPEH_01691 6.8e-95 ureI S AmiS/UreI family transporter
HHILKPEH_01692 1.4e-54 S Domain of unknown function (DUF4173)
HHILKPEH_01693 3.7e-22 yhaI L Membrane
HHILKPEH_01694 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HHILKPEH_01695 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HHILKPEH_01696 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HHILKPEH_01697 1.6e-32 V protein secretion by the type I secretion system
HHILKPEH_01698 2.5e-161 K sequence-specific DNA binding
HHILKPEH_01699 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HHILKPEH_01700 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHILKPEH_01701 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHILKPEH_01702 1.8e-248 trkA P Potassium transporter peripheral membrane component
HHILKPEH_01703 1.2e-258 trkH P Cation transport protein
HHILKPEH_01704 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HHILKPEH_01705 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHILKPEH_01706 2.3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHILKPEH_01707 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHILKPEH_01708 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HHILKPEH_01709 5.4e-86 ykuL S CBS domain
HHILKPEH_01710 3.5e-99 XK27_09740 S Phosphoesterase
HHILKPEH_01711 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHILKPEH_01712 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HHILKPEH_01713 7.6e-36 yneF S UPF0154 protein
HHILKPEH_01714 9.6e-92 K transcriptional regulator
HHILKPEH_01715 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHILKPEH_01718 1.5e-97 ybhL S Belongs to the BI1 family
HHILKPEH_01719 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HHILKPEH_01720 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHILKPEH_01721 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HHILKPEH_01722 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHILKPEH_01723 5.3e-89 L Integrase core domain protein
HHILKPEH_01724 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHILKPEH_01725 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHILKPEH_01726 9.3e-46 XK27_09675 K -acetyltransferase
HHILKPEH_01727 3.1e-20 XK27_09675 K -acetyltransferase
HHILKPEH_01728 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HHILKPEH_01729 2.5e-23
HHILKPEH_01730 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HHILKPEH_01731 1e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HHILKPEH_01732 7.9e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HHILKPEH_01733 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHILKPEH_01734 3.1e-95 ypsA S Belongs to the UPF0398 family
HHILKPEH_01735 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHILKPEH_01736 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHILKPEH_01737 4.6e-260 pepC 3.4.22.40 E aminopeptidase
HHILKPEH_01738 1.9e-77 yhaI L Membrane
HHILKPEH_01739 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHILKPEH_01740 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHILKPEH_01741 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
HHILKPEH_01742 2.6e-76 S thiolester hydrolase activity
HHILKPEH_01744 3.8e-40 K transcriptional
HHILKPEH_01745 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHILKPEH_01746 3.9e-21 glcR K transcriptional regulator (DeoR family)
HHILKPEH_01747 2.8e-76 glcR K transcriptional regulator (DeoR family)
HHILKPEH_01748 4e-34 cof Q phosphatase activity
HHILKPEH_01749 6e-55 cof Q phosphatase activity
HHILKPEH_01750 1.2e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HHILKPEH_01751 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HHILKPEH_01752 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
HHILKPEH_01753 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHILKPEH_01754 7.3e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHILKPEH_01755 6.8e-56 S TM2 domain
HHILKPEH_01756 4.7e-43
HHILKPEH_01760 0.0 M family 8
HHILKPEH_01761 2.7e-09
HHILKPEH_01762 9.6e-08
HHILKPEH_01763 5.8e-109 MA20_06410 E LysE type translocator
HHILKPEH_01764 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
HHILKPEH_01765 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
HHILKPEH_01766 1.9e-35
HHILKPEH_01767 5.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHILKPEH_01768 4.5e-61
HHILKPEH_01769 9.3e-72 S Signal peptide protein, YSIRK family
HHILKPEH_01770 1.6e-53 K response regulator
HHILKPEH_01771 1.1e-37 BP1961 P nitric oxide dioxygenase activity
HHILKPEH_01773 2.7e-285 XK27_07020 S Belongs to the UPF0371 family
HHILKPEH_01774 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HHILKPEH_01775 0.0 L DEAD-like helicases superfamily
HHILKPEH_01776 1.6e-140 S Abortive infection C-terminus
HHILKPEH_01777 2.4e-09
HHILKPEH_01778 5.6e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHILKPEH_01779 3.1e-161 yvgN C reductase
HHILKPEH_01780 2.4e-75 yoaK S Protein of unknown function (DUF1275)
HHILKPEH_01781 1.3e-111 drgA C Nitroreductase
HHILKPEH_01782 2.4e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHILKPEH_01783 6.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
HHILKPEH_01784 3.3e-77 ywnA K Transcriptional regulator
HHILKPEH_01785 2.1e-154 1.13.11.2 S glyoxalase
HHILKPEH_01786 6.1e-111 XK27_02070 S nitroreductase
HHILKPEH_01787 1.5e-245 yfnA E amino acid
HHILKPEH_01788 9.6e-26 csbD K CsbD-like
HHILKPEH_01789 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHILKPEH_01790 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHILKPEH_01791 7.8e-236 brnQ E Component of the transport system for branched-chain amino acids
HHILKPEH_01792 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHILKPEH_01793 5.3e-248 norM V Multidrug efflux pump
HHILKPEH_01794 9.2e-119 pbuX F xanthine permease
HHILKPEH_01795 3.3e-69 pbuX F xanthine permease
HHILKPEH_01797 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHILKPEH_01798 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHILKPEH_01799 6.2e-166 T Histidine kinase
HHILKPEH_01800 5.8e-135 macB2 V ABC transporter, ATP-binding protein
HHILKPEH_01801 0.0 V ABC transporter (permease)
HHILKPEH_01802 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
HHILKPEH_01803 2.6e-30 liaI KT membrane
HHILKPEH_01804 1.6e-14 liaI KT membrane
HHILKPEH_01805 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
HHILKPEH_01806 3.7e-122 S An automated process has identified a potential problem with this gene model
HHILKPEH_01808 3.9e-41 3.6.1.55 F NUDIX domain
HHILKPEH_01809 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
HHILKPEH_01810 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
HHILKPEH_01811 2.3e-213 EGP Major facilitator Superfamily
HHILKPEH_01815 2.1e-160 XK27_09825 V 'abc transporter, ATP-binding protein
HHILKPEH_01816 7.4e-135 yvfS V ABC-2 type transporter
HHILKPEH_01817 4.2e-195 desK 2.7.13.3 T Histidine kinase
HHILKPEH_01818 1.8e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHILKPEH_01819 4.1e-150 S transport system, permease component
HHILKPEH_01820 7.6e-146 S ABC-2 family transporter protein
HHILKPEH_01821 2.3e-27
HHILKPEH_01822 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
HHILKPEH_01823 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
HHILKPEH_01824 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HHILKPEH_01825 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHILKPEH_01826 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHILKPEH_01827 1.6e-77 sigH K DNA-templated transcription, initiation
HHILKPEH_01828 3e-148 ykuT M mechanosensitive ion channel
HHILKPEH_01829 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHILKPEH_01830 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHILKPEH_01831 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHILKPEH_01832 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
HHILKPEH_01833 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HHILKPEH_01834 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
HHILKPEH_01835 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHILKPEH_01836 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HHILKPEH_01837 2.4e-83 nrdI F Belongs to the NrdI family
HHILKPEH_01838 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHILKPEH_01839 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHILKPEH_01840 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HHILKPEH_01841 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HHILKPEH_01842 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HHILKPEH_01843 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HHILKPEH_01844 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHILKPEH_01845 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHILKPEH_01846 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HHILKPEH_01847 6.5e-202 yhjX P Major Facilitator
HHILKPEH_01848 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHILKPEH_01849 5e-94 V VanZ like family
HHILKPEH_01852 1e-123 glnQ E abc transporter atp-binding protein
HHILKPEH_01853 1.8e-276 glnP P ABC transporter
HHILKPEH_01854 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHILKPEH_01855 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HHILKPEH_01856 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
HHILKPEH_01857 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HHILKPEH_01858 6.3e-235 sufD O assembly protein SufD
HHILKPEH_01859 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHILKPEH_01860 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
HHILKPEH_01861 3.5e-274 sufB O assembly protein SufB
HHILKPEH_01862 2.4e-19 oppA E ABC transporter substrate-binding protein
HHILKPEH_01863 5.4e-99 oppA E ABC transporter substrate-binding protein
HHILKPEH_01864 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHILKPEH_01865 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHILKPEH_01866 5.4e-46 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHILKPEH_01867 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHILKPEH_01868 8e-28 oppD P Belongs to the ABC transporter superfamily
HHILKPEH_01869 2.5e-32 oppD P Belongs to the ABC transporter superfamily
HHILKPEH_01870 4.8e-67 oppD P Belongs to the ABC transporter superfamily
HHILKPEH_01871 1.3e-44 oppD P Belongs to the ABC transporter superfamily
HHILKPEH_01872 9e-170 oppF P Belongs to the ABC transporter superfamily
HHILKPEH_01875 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHILKPEH_01876 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHILKPEH_01877 1.9e-209 EGP Major facilitator Superfamily
HHILKPEH_01878 3.1e-72 adcR K transcriptional
HHILKPEH_01879 2.2e-136 adcC P ABC transporter, ATP-binding protein
HHILKPEH_01880 5.4e-131 adcB P ABC transporter (Permease
HHILKPEH_01881 4.8e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HHILKPEH_01882 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
HHILKPEH_01883 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
HHILKPEH_01884 1.7e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HHILKPEH_01885 1e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
HHILKPEH_01886 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
HHILKPEH_01887 1.9e-127 yeeN K transcriptional regulatory protein
HHILKPEH_01888 9.8e-50 yajC U protein transport
HHILKPEH_01889 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHILKPEH_01890 1.3e-145 cdsA 2.7.7.41 S Belongs to the CDS family
HHILKPEH_01891 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HHILKPEH_01892 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHILKPEH_01893 0.0 WQ51_06230 S ABC transporter substrate binding protein
HHILKPEH_01894 5.2e-142 cmpC S abc transporter atp-binding protein
HHILKPEH_01895 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHILKPEH_01896 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHILKPEH_01897 4.4e-37 L Transposase
HHILKPEH_01898 6.4e-18 L transposase activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)