ORF_ID e_value Gene_name EC_number CAZy COGs Description
EMCNNKKH_00001 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EMCNNKKH_00002 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
EMCNNKKH_00003 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
EMCNNKKH_00004 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EMCNNKKH_00005 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EMCNNKKH_00006 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EMCNNKKH_00007 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMCNNKKH_00008 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMCNNKKH_00009 1e-68 S cog cog4699
EMCNNKKH_00010 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EMCNNKKH_00011 1.1e-156 cglB U protein transport across the cell outer membrane
EMCNNKKH_00012 8.5e-43 comGC U Required for transformation and DNA binding
EMCNNKKH_00013 1.8e-57 cglD NU Competence protein
EMCNNKKH_00014 1.4e-15 NU Type II secretory pathway pseudopilin
EMCNNKKH_00015 1.5e-71 comGF U Competence protein ComGF
EMCNNKKH_00016 2e-12 comGF U Putative Competence protein ComGF
EMCNNKKH_00017 5.9e-177 ytxK 2.1.1.72 L DNA methylase
EMCNNKKH_00018 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EMCNNKKH_00019 8.8e-27 lanR K sequence-specific DNA binding
EMCNNKKH_00020 1.4e-33 V CAAX protease self-immunity
EMCNNKKH_00021 5e-67 V CAAX protease self-immunity
EMCNNKKH_00023 1.8e-111 S CAAX amino terminal protease family protein
EMCNNKKH_00024 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EMCNNKKH_00025 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
EMCNNKKH_00026 4.1e-09 S Domain of unknown function (DUF4651)
EMCNNKKH_00027 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
EMCNNKKH_00028 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EMCNNKKH_00029 2.8e-193 yeeE S Sulphur transport
EMCNNKKH_00030 8.3e-37 yeeD O sulfur carrier activity
EMCNNKKH_00031 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EMCNNKKH_00032 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EMCNNKKH_00035 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
EMCNNKKH_00036 1.5e-64 S phosphatase activity
EMCNNKKH_00037 2.7e-48 S glycolate biosynthetic process
EMCNNKKH_00038 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
EMCNNKKH_00039 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
EMCNNKKH_00040 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EMCNNKKH_00041 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
EMCNNKKH_00042 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
EMCNNKKH_00043 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
EMCNNKKH_00044 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
EMCNNKKH_00045 3.2e-62 fnt P Formate nitrite transporter
EMCNNKKH_00046 1e-141 XK27_09615 C reductase
EMCNNKKH_00047 9e-62 XK27_09615 C reductase
EMCNNKKH_00048 4.3e-77 XK27_09620 S reductase
EMCNNKKH_00049 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
EMCNNKKH_00050 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EMCNNKKH_00051 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EMCNNKKH_00052 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
EMCNNKKH_00053 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
EMCNNKKH_00054 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
EMCNNKKH_00055 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EMCNNKKH_00056 9.2e-51 S Protein of unknown function (DUF3397)
EMCNNKKH_00057 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EMCNNKKH_00058 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EMCNNKKH_00059 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
EMCNNKKH_00060 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
EMCNNKKH_00061 2e-41 amiA E transmembrane transport
EMCNNKKH_00062 6.7e-81 amiA E transmembrane transport
EMCNNKKH_00063 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EMCNNKKH_00064 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EMCNNKKH_00065 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
EMCNNKKH_00066 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
EMCNNKKH_00067 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EMCNNKKH_00068 2e-186 jag S RNA-binding protein
EMCNNKKH_00069 1e-13 rpmH J Ribosomal protein L34
EMCNNKKH_00070 1e-33 L Transposase
EMCNNKKH_00071 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EMCNNKKH_00072 1e-114 papP P ABC transporter (Permease
EMCNNKKH_00073 3.5e-115 P ABC transporter (Permease
EMCNNKKH_00074 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
EMCNNKKH_00075 1.1e-155 cjaA ET ABC transporter substrate-binding protein
EMCNNKKH_00079 1e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EMCNNKKH_00080 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
EMCNNKKH_00081 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EMCNNKKH_00082 1.9e-201 yjbB G Permeases of the major facilitator superfamily
EMCNNKKH_00083 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EMCNNKKH_00084 2.3e-99 thiT S Thiamine transporter
EMCNNKKH_00085 1.9e-62 yjqA S Bacterial PH domain
EMCNNKKH_00086 2.3e-154 corA P CorA-like protein
EMCNNKKH_00087 2.4e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
EMCNNKKH_00088 1e-41 yazA L endonuclease containing a URI domain
EMCNNKKH_00089 7.1e-141 yabB 2.1.1.223 L Methyltransferase
EMCNNKKH_00090 1.8e-140 nodB3 G deacetylase
EMCNNKKH_00091 1.7e-142 plsC 2.3.1.51 I Acyltransferase
EMCNNKKH_00092 1.3e-34 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EMCNNKKH_00093 2.9e-48 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
EMCNNKKH_00094 0.0 comEC S Competence protein ComEC
EMCNNKKH_00095 1.5e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EMCNNKKH_00096 1.1e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
EMCNNKKH_00097 3e-232 ytoI K transcriptional regulator containing CBS domains
EMCNNKKH_00098 1.9e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
EMCNNKKH_00099 5.8e-161 rbn E Belongs to the UPF0761 family
EMCNNKKH_00100 2.2e-85 ccl S cog cog4708
EMCNNKKH_00101 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EMCNNKKH_00102 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
EMCNNKKH_00103 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
EMCNNKKH_00104 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
EMCNNKKH_00105 2.1e-74 S QueT transporter
EMCNNKKH_00106 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
EMCNNKKH_00107 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
EMCNNKKH_00108 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EMCNNKKH_00109 4.1e-37 ylqC L Belongs to the UPF0109 family
EMCNNKKH_00110 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EMCNNKKH_00111 0.0 ydaO E amino acid
EMCNNKKH_00112 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
EMCNNKKH_00113 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EMCNNKKH_00114 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
EMCNNKKH_00115 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EMCNNKKH_00116 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EMCNNKKH_00117 7.8e-171 murB 1.3.1.98 M cell wall formation
EMCNNKKH_00118 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EMCNNKKH_00119 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
EMCNNKKH_00120 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
EMCNNKKH_00121 2.3e-206 potD P spermidine putrescine ABC transporter
EMCNNKKH_00122 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
EMCNNKKH_00123 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
EMCNNKKH_00124 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
EMCNNKKH_00125 2.1e-25 GK ROK family
EMCNNKKH_00126 4.6e-58 GK ROK family
EMCNNKKH_00127 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EMCNNKKH_00128 3.9e-104 wecD M Acetyltransferase GNAT family
EMCNNKKH_00129 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EMCNNKKH_00130 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
EMCNNKKH_00131 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
EMCNNKKH_00133 7.7e-56 lrgA S Effector of murein hydrolase LrgA
EMCNNKKH_00134 2.2e-117 lrgB M effector of murein hydrolase
EMCNNKKH_00135 2.6e-109 3.1.3.18 S IA, variant 1
EMCNNKKH_00136 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EMCNNKKH_00137 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
EMCNNKKH_00138 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EMCNNKKH_00139 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EMCNNKKH_00140 1e-134 parB K Belongs to the ParB family
EMCNNKKH_00141 1.5e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
EMCNNKKH_00142 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EMCNNKKH_00143 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
EMCNNKKH_00147 0.0 XK27_10405 S Bacterial membrane protein YfhO
EMCNNKKH_00148 6.7e-306 ybiT S abc transporter atp-binding protein
EMCNNKKH_00149 1.1e-153 yvjA S membrane
EMCNNKKH_00150 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
EMCNNKKH_00151 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EMCNNKKH_00152 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EMCNNKKH_00153 1.6e-45 yaaA S S4 domain protein YaaA
EMCNNKKH_00154 4.8e-235 ymfF S Peptidase M16
EMCNNKKH_00155 1.1e-242 ymfH S Peptidase M16
EMCNNKKH_00156 3.7e-138 ymfM S sequence-specific DNA binding
EMCNNKKH_00157 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EMCNNKKH_00158 7.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMCNNKKH_00159 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMCNNKKH_00160 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EMCNNKKH_00161 3.1e-93 lytE M LysM domain protein
EMCNNKKH_00162 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
EMCNNKKH_00163 0.0 S Bacterial membrane protein, YfhO
EMCNNKKH_00164 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
EMCNNKKH_00165 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
EMCNNKKH_00166 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
EMCNNKKH_00167 3.9e-70 rplI J binds to the 23S rRNA
EMCNNKKH_00168 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EMCNNKKH_00169 8.2e-48 veg S Biofilm formation stimulator VEG
EMCNNKKH_00170 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EMCNNKKH_00171 2.7e-08
EMCNNKKH_00172 4.8e-55 ypaA M Membrane
EMCNNKKH_00173 6.4e-96 XK27_06935 K transcriptional regulator
EMCNNKKH_00174 3.9e-161 XK27_06930 V domain protein
EMCNNKKH_00175 1.8e-88 S Putative adhesin
EMCNNKKH_00176 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
EMCNNKKH_00178 1.7e-23 K negative regulation of transcription, DNA-templated
EMCNNKKH_00179 4e-19 K negative regulation of transcription, DNA-templated
EMCNNKKH_00180 3.4e-13 nudL L hydrolase
EMCNNKKH_00181 7.2e-95 nudL L hydrolase
EMCNNKKH_00182 4.9e-12 K CsbD-like
EMCNNKKH_00183 1.1e-71 M Protein conserved in bacteria
EMCNNKKH_00184 1.8e-23 S Small integral membrane protein
EMCNNKKH_00185 3.1e-101
EMCNNKKH_00186 3.7e-27 S Membrane
EMCNNKKH_00188 2.7e-95 S Hydrophobic domain protein
EMCNNKKH_00189 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
EMCNNKKH_00191 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
EMCNNKKH_00192 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EMCNNKKH_00193 9.2e-36 metE 2.1.1.14 E Methionine synthase
EMCNNKKH_00194 7.6e-64 metE 2.1.1.14 E Methionine synthase
EMCNNKKH_00195 5.7e-52 metE 2.1.1.14 E Methionine synthase
EMCNNKKH_00196 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
EMCNNKKH_00198 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
EMCNNKKH_00199 9.9e-169 XK27_01785 S cog cog1284
EMCNNKKH_00200 7e-147 yaaA S Belongs to the UPF0246 family
EMCNNKKH_00201 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EMCNNKKH_00202 2.6e-91 XK27_10930 K acetyltransferase
EMCNNKKH_00203 7.5e-14
EMCNNKKH_00204 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
EMCNNKKH_00205 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
EMCNNKKH_00206 3.7e-151 K Helix-turn-helix XRE-family like proteins
EMCNNKKH_00207 9.2e-284 V ABC transporter transmembrane region
EMCNNKKH_00208 2.9e-31 yozG K Transcriptional regulator
EMCNNKKH_00211 2.1e-185 V Abi-like protein
EMCNNKKH_00213 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EMCNNKKH_00214 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EMCNNKKH_00215 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EMCNNKKH_00216 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EMCNNKKH_00217 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EMCNNKKH_00218 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EMCNNKKH_00220 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
EMCNNKKH_00221 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
EMCNNKKH_00222 0.0 scrA 2.7.1.211 G pts system
EMCNNKKH_00223 5.4e-291 scrB 3.2.1.26 GH32 G invertase
EMCNNKKH_00224 7.5e-180 scrR K Transcriptional
EMCNNKKH_00225 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EMCNNKKH_00226 3.4e-62 yqhY S protein conserved in bacteria
EMCNNKKH_00227 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EMCNNKKH_00228 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
EMCNNKKH_00229 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
EMCNNKKH_00231 8e-44 V 'abc transporter, ATP-binding protein
EMCNNKKH_00232 3.8e-58 V 'abc transporter, ATP-binding protein
EMCNNKKH_00235 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EMCNNKKH_00236 2e-169 corA P COG0598 Mg2 and Co2 transporters
EMCNNKKH_00237 3.1e-124 XK27_01040 S Pfam PF06570
EMCNNKKH_00239 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EMCNNKKH_00240 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
EMCNNKKH_00241 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
EMCNNKKH_00242 3.6e-41 XK27_05745
EMCNNKKH_00243 2.5e-230 mutY L A G-specific adenine glycosylase
EMCNNKKH_00249 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EMCNNKKH_00250 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
EMCNNKKH_00251 1e-93 cvpA S toxin biosynthetic process
EMCNNKKH_00252 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EMCNNKKH_00253 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EMCNNKKH_00254 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EMCNNKKH_00255 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EMCNNKKH_00256 2e-47 azlD E branched-chain amino acid
EMCNNKKH_00257 1.3e-117 azlC E AzlC protein
EMCNNKKH_00258 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EMCNNKKH_00259 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
EMCNNKKH_00260 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
EMCNNKKH_00261 2.5e-33 ykzG S Belongs to the UPF0356 family
EMCNNKKH_00262 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EMCNNKKH_00263 2.7e-40 pscB M CHAP domain protein
EMCNNKKH_00264 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
EMCNNKKH_00265 8.5e-63 glnR K Transcriptional regulator
EMCNNKKH_00266 1.3e-87 S Fusaric acid resistance protein-like
EMCNNKKH_00267 7.4e-165 hrtB V MacB-like periplasmic core domain
EMCNNKKH_00270 3e-92 S MucBP domain
EMCNNKKH_00271 6.5e-50 M YSIRK type signal peptide
EMCNNKKH_00272 0.0 M the current gene model (or a revised gene model) may contain a
EMCNNKKH_00274 0.0 mdlB V abc transporter atp-binding protein
EMCNNKKH_00275 0.0 lmrA V abc transporter atp-binding protein
EMCNNKKH_00276 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EMCNNKKH_00277 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EMCNNKKH_00278 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
EMCNNKKH_00279 2.5e-132 rr02 KT response regulator
EMCNNKKH_00280 7.1e-214 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
EMCNNKKH_00281 2.8e-168 V ABC transporter
EMCNNKKH_00282 5.4e-122 sagI S ABC-2 type transporter
EMCNNKKH_00283 2.4e-197 yceA S Belongs to the UPF0176 family
EMCNNKKH_00284 8e-28 XK27_00085 K Transcriptional
EMCNNKKH_00285 1.1e-22
EMCNNKKH_00286 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
EMCNNKKH_00287 8.7e-114 S VIT family
EMCNNKKH_00288 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EMCNNKKH_00289 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EMCNNKKH_00290 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
EMCNNKKH_00291 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
EMCNNKKH_00292 6.1e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EMCNNKKH_00293 4.6e-105 GBS0088 J protein conserved in bacteria
EMCNNKKH_00294 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
EMCNNKKH_00295 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
EMCNNKKH_00296 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
EMCNNKKH_00297 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
EMCNNKKH_00298 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EMCNNKKH_00299 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
EMCNNKKH_00300 2.5e-21
EMCNNKKH_00301 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EMCNNKKH_00303 2.1e-50 U protein secretion
EMCNNKKH_00305 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
EMCNNKKH_00306 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
EMCNNKKH_00307 4.9e-21 XK27_13030
EMCNNKKH_00308 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EMCNNKKH_00309 8.9e-57 S hydrolase activity, acting on ester bonds
EMCNNKKH_00310 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
EMCNNKKH_00311 8.6e-167 S Protein of unknown function (DUF3114)
EMCNNKKH_00312 1.2e-22 S Protein of unknown function (DUF3114)
EMCNNKKH_00313 1.5e-118 yqfA K protein, Hemolysin III
EMCNNKKH_00314 1e-25 K hmm pf08876
EMCNNKKH_00315 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
EMCNNKKH_00316 1.7e-218 mvaS 2.3.3.10 I synthase
EMCNNKKH_00317 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EMCNNKKH_00318 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EMCNNKKH_00319 9.7e-22
EMCNNKKH_00320 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EMCNNKKH_00321 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
EMCNNKKH_00322 5.2e-251 mmuP E amino acid
EMCNNKKH_00323 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
EMCNNKKH_00324 1.4e-29 S Domain of unknown function (DUF1912)
EMCNNKKH_00325 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
EMCNNKKH_00326 0.0 yfmR S abc transporter atp-binding protein
EMCNNKKH_00327 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
EMCNNKKH_00328 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EMCNNKKH_00329 3.6e-74 XK27_08360 S EDD domain protein, DegV family
EMCNNKKH_00330 6.4e-61 XK27_08360 S EDD domain protein, DegV family
EMCNNKKH_00331 2.6e-64 WQ51_03320 S cog cog4835
EMCNNKKH_00332 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EMCNNKKH_00333 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
EMCNNKKH_00334 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
EMCNNKKH_00335 6.4e-29 2.3.1.128 K acetyltransferase
EMCNNKKH_00336 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
EMCNNKKH_00337 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
EMCNNKKH_00338 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EMCNNKKH_00339 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
EMCNNKKH_00341 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
EMCNNKKH_00342 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EMCNNKKH_00343 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
EMCNNKKH_00344 5.1e-145 fruA 2.7.1.202 G phosphotransferase system
EMCNNKKH_00345 8e-98 fruA 2.7.1.202 G phosphotransferase system
EMCNNKKH_00346 2.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
EMCNNKKH_00347 5.6e-114 fruR K transcriptional
EMCNNKKH_00348 1.8e-84 L Transposase
EMCNNKKH_00349 1.1e-202 rny D Endoribonuclease that initiates mRNA decay
EMCNNKKH_00350 1.4e-65 tnp L Transposase
EMCNNKKH_00351 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EMCNNKKH_00352 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
EMCNNKKH_00353 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EMCNNKKH_00354 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
EMCNNKKH_00355 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
EMCNNKKH_00356 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
EMCNNKKH_00357 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
EMCNNKKH_00358 1.6e-126 IQ reductase
EMCNNKKH_00359 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
EMCNNKKH_00360 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
EMCNNKKH_00361 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMCNNKKH_00362 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EMCNNKKH_00363 4e-72 marR K Transcriptional regulator, MarR family
EMCNNKKH_00364 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
EMCNNKKH_00365 1.9e-115 S Haloacid dehalogenase-like hydrolase
EMCNNKKH_00366 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
EMCNNKKH_00367 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
EMCNNKKH_00368 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EMCNNKKH_00369 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
EMCNNKKH_00370 1.3e-101 ygaC J Belongs to the UPF0374 family
EMCNNKKH_00371 6.4e-108 S Domain of unknown function (DUF1803)
EMCNNKKH_00372 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
EMCNNKKH_00379 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
EMCNNKKH_00380 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
EMCNNKKH_00381 0.0 dnaE 2.7.7.7 L DNA polymerase
EMCNNKKH_00382 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
EMCNNKKH_00383 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EMCNNKKH_00384 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EMCNNKKH_00385 2.5e-43 ysdA L Membrane
EMCNNKKH_00386 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EMCNNKKH_00387 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EMCNNKKH_00388 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EMCNNKKH_00389 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
EMCNNKKH_00391 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
EMCNNKKH_00392 2.1e-84 ypmS S Protein conserved in bacteria
EMCNNKKH_00393 1.3e-143 ypmR E lipolytic protein G-D-S-L family
EMCNNKKH_00394 1e-148 DegV S DegV family
EMCNNKKH_00395 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
EMCNNKKH_00396 3.7e-73 argR K Regulates arginine biosynthesis genes
EMCNNKKH_00397 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EMCNNKKH_00398 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
EMCNNKKH_00399 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
EMCNNKKH_00400 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EMCNNKKH_00403 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EMCNNKKH_00404 2.9e-125 dnaD
EMCNNKKH_00405 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EMCNNKKH_00406 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EMCNNKKH_00407 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
EMCNNKKH_00408 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EMCNNKKH_00409 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
EMCNNKKH_00410 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EMCNNKKH_00411 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EMCNNKKH_00412 5.4e-197 L transposase, IS4 family
EMCNNKKH_00413 5.6e-240 rodA D Belongs to the SEDS family
EMCNNKKH_00414 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
EMCNNKKH_00415 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EMCNNKKH_00416 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EMCNNKKH_00417 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EMCNNKKH_00418 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EMCNNKKH_00419 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
EMCNNKKH_00420 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EMCNNKKH_00421 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
EMCNNKKH_00422 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EMCNNKKH_00423 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EMCNNKKH_00425 6.6e-31 L Integrase core domain protein
EMCNNKKH_00426 1.6e-24 U response to pH
EMCNNKKH_00427 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
EMCNNKKH_00428 2.1e-204 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
EMCNNKKH_00429 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EMCNNKKH_00430 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EMCNNKKH_00431 1.9e-77 K DNA-binding transcription factor activity
EMCNNKKH_00432 0.0 lmrA1 V abc transporter atp-binding protein
EMCNNKKH_00433 0.0 lmrA2 V abc transporter atp-binding protein
EMCNNKKH_00434 1.6e-44 K Acetyltransferase (GNAT) family
EMCNNKKH_00435 2.9e-120 sptS 2.7.13.3 T Histidine kinase
EMCNNKKH_00436 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EMCNNKKH_00437 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EMCNNKKH_00438 5.3e-161 cvfB S Protein conserved in bacteria
EMCNNKKH_00439 7.4e-35 yozE S Belongs to the UPF0346 family
EMCNNKKH_00440 8.1e-126 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
EMCNNKKH_00441 2.3e-61 rlpA M LysM domain protein
EMCNNKKH_00442 8e-191 phoH T phosphate starvation-inducible protein PhoH
EMCNNKKH_00446 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EMCNNKKH_00447 1.8e-167 K transcriptional regulator (lysR family)
EMCNNKKH_00448 1.4e-186 coiA 3.6.4.12 S Competence protein
EMCNNKKH_00449 0.0 pepF E oligoendopeptidase F
EMCNNKKH_00450 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
EMCNNKKH_00451 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
EMCNNKKH_00452 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EMCNNKKH_00453 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EMCNNKKH_00454 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EMCNNKKH_00455 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
EMCNNKKH_00456 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
EMCNNKKH_00457 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
EMCNNKKH_00458 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
EMCNNKKH_00459 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EMCNNKKH_00460 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EMCNNKKH_00461 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EMCNNKKH_00462 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
EMCNNKKH_00463 8.5e-142 yxkH G deacetylase
EMCNNKKH_00470 5.3e-11
EMCNNKKH_00476 1.3e-140 mreC M Involved in formation and maintenance of cell shape
EMCNNKKH_00477 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EMCNNKKH_00478 8.9e-102 usp 3.5.1.28 CBM50 S CHAP domain
EMCNNKKH_00479 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EMCNNKKH_00480 2.5e-26
EMCNNKKH_00481 5.9e-219 araT 2.6.1.1 E Aminotransferase
EMCNNKKH_00482 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
EMCNNKKH_00483 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
EMCNNKKH_00484 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
EMCNNKKH_00485 5.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EMCNNKKH_00486 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EMCNNKKH_00487 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EMCNNKKH_00488 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EMCNNKKH_00489 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EMCNNKKH_00490 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EMCNNKKH_00491 1.1e-89 L transposase activity
EMCNNKKH_00492 3.5e-50 L transposition
EMCNNKKH_00493 2e-32 L Integrase core domain protein
EMCNNKKH_00494 2.3e-161 S CHAP domain
EMCNNKKH_00495 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
EMCNNKKH_00496 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EMCNNKKH_00497 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EMCNNKKH_00498 9.2e-141 1.1.1.169 H Ketopantoate reductase
EMCNNKKH_00499 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EMCNNKKH_00500 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EMCNNKKH_00501 8.2e-70 argR K Regulates arginine biosynthesis genes
EMCNNKKH_00502 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
EMCNNKKH_00503 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EMCNNKKH_00504 1.9e-80 S Protein of unknown function (DUF3021)
EMCNNKKH_00505 6.5e-63 KT phosphorelay signal transduction system
EMCNNKKH_00507 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EMCNNKKH_00509 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EMCNNKKH_00510 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
EMCNNKKH_00511 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
EMCNNKKH_00512 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EMCNNKKH_00513 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
EMCNNKKH_00514 4.8e-196 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
EMCNNKKH_00515 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EMCNNKKH_00516 3.2e-92 dps P Belongs to the Dps family
EMCNNKKH_00517 1.1e-80 perR P Belongs to the Fur family
EMCNNKKH_00518 8.4e-28 yqgQ S protein conserved in bacteria
EMCNNKKH_00519 2.2e-179 glk 2.7.1.2 G Glucokinase
EMCNNKKH_00520 0.0 typA T GTP-binding protein TypA
EMCNNKKH_00522 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EMCNNKKH_00523 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EMCNNKKH_00524 6.7e-172 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
EMCNNKKH_00525 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
EMCNNKKH_00526 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EMCNNKKH_00527 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EMCNNKKH_00528 1.4e-96 sepF D cell septum assembly
EMCNNKKH_00529 2e-34 yggT D integral membrane protein
EMCNNKKH_00530 4.2e-144 ylmH T S4 RNA-binding domain
EMCNNKKH_00531 1.8e-135 divIVA D Cell division protein DivIVA
EMCNNKKH_00532 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EMCNNKKH_00533 8.4e-10
EMCNNKKH_00534 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
EMCNNKKH_00535 2e-45 rpmE2 J 50S ribosomal protein L31
EMCNNKKH_00536 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EMCNNKKH_00537 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
EMCNNKKH_00538 2.4e-155 gst O Glutathione S-transferase
EMCNNKKH_00539 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EMCNNKKH_00540 4.5e-111 tdk 2.7.1.21 F thymidine kinase
EMCNNKKH_00541 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EMCNNKKH_00542 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EMCNNKKH_00543 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
EMCNNKKH_00544 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EMCNNKKH_00545 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
EMCNNKKH_00546 6e-106 pvaA M lytic transglycosylase activity
EMCNNKKH_00547 0.0 yfiB1 V abc transporter atp-binding protein
EMCNNKKH_00548 0.0 XK27_10035 V abc transporter atp-binding protein
EMCNNKKH_00549 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
EMCNNKKH_00550 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EMCNNKKH_00551 4.6e-238 dltB M Membrane protein involved in D-alanine export
EMCNNKKH_00552 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EMCNNKKH_00553 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
EMCNNKKH_00554 1.2e-32 L Integrase core domain protein
EMCNNKKH_00555 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
EMCNNKKH_00556 1.9e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
EMCNNKKH_00557 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EMCNNKKH_00558 6.2e-56 S Domain of unknown function (DUF4430)
EMCNNKKH_00559 1.8e-73 S Psort location CytoplasmicMembrane, score
EMCNNKKH_00560 6.4e-133 htpX O Belongs to the peptidase M48B family
EMCNNKKH_00561 9e-93 lemA S LemA family
EMCNNKKH_00562 9.9e-90 spd F DNA RNA non-specific endonuclease
EMCNNKKH_00563 1e-36 spd F DNA RNA non-specific endonuclease
EMCNNKKH_00564 5.9e-22 S PD-(D/E)XK nuclease family transposase
EMCNNKKH_00565 6.6e-306 hsdM 2.1.1.72 V type I restriction-modification system
EMCNNKKH_00566 1e-136 S Protein conserved in bacteria
EMCNNKKH_00567 2.2e-105
EMCNNKKH_00568 2.8e-221 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
EMCNNKKH_00570 1.2e-216 S Bacteriophage abortive infection AbiH
EMCNNKKH_00571 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EMCNNKKH_00572 7.6e-71 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EMCNNKKH_00573 8.7e-45 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EMCNNKKH_00574 9.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
EMCNNKKH_00575 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
EMCNNKKH_00576 1.6e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EMCNNKKH_00577 2.7e-27 P Hemerythrin HHE cation binding domain protein
EMCNNKKH_00578 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
EMCNNKKH_00579 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EMCNNKKH_00580 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
EMCNNKKH_00581 2.3e-175 S hydrolase
EMCNNKKH_00582 7.6e-16
EMCNNKKH_00583 1e-163 M LysM domain
EMCNNKKH_00584 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EMCNNKKH_00585 4.2e-117
EMCNNKKH_00586 7.7e-238 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
EMCNNKKH_00587 1.9e-12
EMCNNKKH_00588 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
EMCNNKKH_00589 1.1e-33 XK27_12190 S protein conserved in bacteria
EMCNNKKH_00591 1.5e-89 bioY S biotin synthase
EMCNNKKH_00592 3.4e-252 yegQ O Peptidase U32
EMCNNKKH_00593 4.4e-177 yegQ O Peptidase U32
EMCNNKKH_00595 5.5e-69 ytxH S General stress protein
EMCNNKKH_00597 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EMCNNKKH_00598 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EMCNNKKH_00599 9.9e-42 pspC KT PspC domain
EMCNNKKH_00600 0.0 yhgF K Transcriptional accessory protein
EMCNNKKH_00602 1.7e-157 XK27_03015 S permease
EMCNNKKH_00603 1.3e-148 ycgQ S TIGR03943 family
EMCNNKKH_00604 2.3e-198 S CRISPR-associated protein Csn2 subfamily St
EMCNNKKH_00605 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMCNNKKH_00606 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMCNNKKH_00607 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EMCNNKKH_00608 4.4e-93
EMCNNKKH_00609 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
EMCNNKKH_00610 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
EMCNNKKH_00611 1e-31 K Cro/C1-type HTH DNA-binding domain
EMCNNKKH_00612 1.2e-45
EMCNNKKH_00613 8.9e-20
EMCNNKKH_00614 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EMCNNKKH_00615 3.5e-97 mip S hydroperoxide reductase activity
EMCNNKKH_00616 2.4e-203 I acyl-CoA dehydrogenase
EMCNNKKH_00617 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
EMCNNKKH_00618 2.6e-253 msrR K Transcriptional regulator
EMCNNKKH_00619 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
EMCNNKKH_00620 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EMCNNKKH_00621 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EMCNNKKH_00622 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EMCNNKKH_00623 3.2e-53 yheA S Belongs to the UPF0342 family
EMCNNKKH_00624 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
EMCNNKKH_00625 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EMCNNKKH_00626 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EMCNNKKH_00627 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EMCNNKKH_00628 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
EMCNNKKH_00629 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
EMCNNKKH_00630 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
EMCNNKKH_00631 2e-25 WQ51_00785
EMCNNKKH_00632 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EMCNNKKH_00633 1e-78 yueI S Protein of unknown function (DUF1694)
EMCNNKKH_00634 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EMCNNKKH_00635 6.6e-101 yyaQ V Protein conserved in bacteria
EMCNNKKH_00636 2.8e-28 yyaQ S YjbR
EMCNNKKH_00637 4.4e-183 ccpA K Catabolite control protein A
EMCNNKKH_00638 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
EMCNNKKH_00639 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
EMCNNKKH_00640 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EMCNNKKH_00641 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EMCNNKKH_00642 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
EMCNNKKH_00643 2.6e-33 secG U Preprotein translocase subunit SecG
EMCNNKKH_00644 9.5e-74 mdtG EGP Major facilitator Superfamily
EMCNNKKH_00645 6e-133 mdtG EGP Major facilitator Superfamily
EMCNNKKH_00646 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EMCNNKKH_00647 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
EMCNNKKH_00648 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EMCNNKKH_00649 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
EMCNNKKH_00650 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EMCNNKKH_00651 6.8e-53 licT K transcriptional antiterminator
EMCNNKKH_00652 9.2e-43 licT K transcriptional antiterminator
EMCNNKKH_00654 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EMCNNKKH_00655 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
EMCNNKKH_00656 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EMCNNKKH_00657 2.1e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EMCNNKKH_00658 7.5e-23 I Alpha/beta hydrolase family
EMCNNKKH_00659 1.5e-35 yugF I carboxylic ester hydrolase activity
EMCNNKKH_00660 2.2e-45 K sequence-specific DNA binding
EMCNNKKH_00661 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EMCNNKKH_00662 1.5e-07
EMCNNKKH_00663 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
EMCNNKKH_00664 1.1e-78 feoA P FeoA domain protein
EMCNNKKH_00665 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
EMCNNKKH_00666 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
EMCNNKKH_00667 1.3e-34 ykuJ S protein conserved in bacteria
EMCNNKKH_00668 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EMCNNKKH_00669 0.0 clpE O Belongs to the ClpA ClpB family
EMCNNKKH_00670 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
EMCNNKKH_00671 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
EMCNNKKH_00672 2.4e-66 S oxidoreductase
EMCNNKKH_00673 1.5e-50 S oxidoreductase
EMCNNKKH_00674 6.8e-234 murN 2.3.2.10, 2.3.2.16 V FemAB family
EMCNNKKH_00675 1.7e-63 M Pfam SNARE associated Golgi protein
EMCNNKKH_00676 1.5e-30 S Domain of Unknown Function with PDB structure (DUF3862)
EMCNNKKH_00677 1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
EMCNNKKH_00680 6.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
EMCNNKKH_00683 4.8e-16 S Protein of unknown function (DUF2969)
EMCNNKKH_00684 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
EMCNNKKH_00685 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EMCNNKKH_00686 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
EMCNNKKH_00687 1.2e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
EMCNNKKH_00688 1.1e-30 ET amino acid transport
EMCNNKKH_00689 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
EMCNNKKH_00690 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
EMCNNKKH_00691 3.8e-205 EGP Transmembrane secretion effector
EMCNNKKH_00692 2.9e-151 ET amino acid transport
EMCNNKKH_00693 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
EMCNNKKH_00694 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
EMCNNKKH_00695 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
EMCNNKKH_00696 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
EMCNNKKH_00697 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EMCNNKKH_00698 3e-98 metI P ABC transporter (Permease
EMCNNKKH_00699 2.7e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EMCNNKKH_00700 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
EMCNNKKH_00701 9.4e-95 S UPF0397 protein
EMCNNKKH_00702 0.0 ykoD P abc transporter atp-binding protein
EMCNNKKH_00703 1.2e-149 cbiQ P cobalt transport
EMCNNKKH_00704 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EMCNNKKH_00705 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
EMCNNKKH_00706 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
EMCNNKKH_00707 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
EMCNNKKH_00708 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
EMCNNKKH_00709 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
EMCNNKKH_00710 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EMCNNKKH_00711 2.8e-282 T PhoQ Sensor
EMCNNKKH_00712 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EMCNNKKH_00713 6.5e-218 dnaB L Replication initiation and membrane attachment
EMCNNKKH_00714 5.2e-167 dnaI L Primosomal protein DnaI
EMCNNKKH_00715 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
EMCNNKKH_00717 1.2e-34
EMCNNKKH_00718 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
EMCNNKKH_00719 3e-27 L Integrase core domain protein
EMCNNKKH_00720 6.2e-36 L transposition
EMCNNKKH_00721 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
EMCNNKKH_00722 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
EMCNNKKH_00724 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
EMCNNKKH_00725 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EMCNNKKH_00726 5.5e-83 S Putative small multi-drug export protein
EMCNNKKH_00727 1.8e-75 ctsR K Belongs to the CtsR family
EMCNNKKH_00728 0.0 clpC O Belongs to the ClpA ClpB family
EMCNNKKH_00729 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EMCNNKKH_00730 1.7e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EMCNNKKH_00731 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
EMCNNKKH_00732 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EMCNNKKH_00733 5.5e-153 rarD S Transporter
EMCNNKKH_00734 2.2e-15 T peptidase
EMCNNKKH_00735 8.9e-14 coiA 3.6.4.12 S Competence protein
EMCNNKKH_00736 6.6e-147 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EMCNNKKH_00737 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EMCNNKKH_00738 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EMCNNKKH_00739 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMCNNKKH_00740 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
EMCNNKKH_00741 3.3e-78 atpF C ATP synthase F(0) sector subunit b
EMCNNKKH_00742 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EMCNNKKH_00743 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EMCNNKKH_00744 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EMCNNKKH_00745 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EMCNNKKH_00746 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EMCNNKKH_00747 2.8e-230 ftsW D Belongs to the SEDS family
EMCNNKKH_00748 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EMCNNKKH_00749 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EMCNNKKH_00750 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EMCNNKKH_00751 6.4e-162 holB 2.7.7.7 L dna polymerase iii
EMCNNKKH_00752 1.2e-135 yaaT S stage 0 sporulation protein
EMCNNKKH_00753 9.5e-55 yabA L Involved in initiation control of chromosome replication
EMCNNKKH_00754 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EMCNNKKH_00755 2.6e-233 amt P Ammonium Transporter
EMCNNKKH_00756 1.1e-53 glnB K Belongs to the P(II) protein family
EMCNNKKH_00757 4.9e-106 mur1 NU mannosyl-glycoprotein
EMCNNKKH_00758 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
EMCNNKKH_00759 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
EMCNNKKH_00760 1.9e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
EMCNNKKH_00761 1.8e-53
EMCNNKKH_00762 7.5e-26
EMCNNKKH_00763 1.5e-59
EMCNNKKH_00764 6.1e-63 S membrane
EMCNNKKH_00765 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
EMCNNKKH_00766 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
EMCNNKKH_00767 4.5e-39 ynzC S UPF0291 protein
EMCNNKKH_00768 1.8e-254 cycA E permease
EMCNNKKH_00769 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
EMCNNKKH_00770 5.8e-71 pts33BCA G pts system
EMCNNKKH_00771 3.5e-143 pts33BCA G pts system
EMCNNKKH_00772 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EMCNNKKH_00773 1.2e-165 L integrase core domain
EMCNNKKH_00774 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EMCNNKKH_00775 4.4e-123 comFC S Competence protein
EMCNNKKH_00776 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
EMCNNKKH_00777 6.3e-111 yvyE 3.4.13.9 S YigZ family
EMCNNKKH_00778 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EMCNNKKH_00779 3.3e-43 acuB S IMP dehydrogenase activity
EMCNNKKH_00780 1.1e-69 acuB S IMP dehydrogenase activity
EMCNNKKH_00781 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
EMCNNKKH_00782 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
EMCNNKKH_00783 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
EMCNNKKH_00784 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
EMCNNKKH_00785 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
EMCNNKKH_00786 7.1e-46 ylbG S UPF0298 protein
EMCNNKKH_00787 3.4e-74 ylbF S Belongs to the UPF0342 family
EMCNNKKH_00788 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EMCNNKKH_00789 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EMCNNKKH_00790 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
EMCNNKKH_00792 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
EMCNNKKH_00793 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
EMCNNKKH_00794 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
EMCNNKKH_00795 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
EMCNNKKH_00796 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EMCNNKKH_00797 3.2e-214 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
EMCNNKKH_00798 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
EMCNNKKH_00799 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
EMCNNKKH_00800 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EMCNNKKH_00801 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EMCNNKKH_00802 1.4e-41 ylxQ J ribosomal protein
EMCNNKKH_00803 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
EMCNNKKH_00804 3.1e-212 nusA K Participates in both transcription termination and antitermination
EMCNNKKH_00805 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
EMCNNKKH_00806 2.5e-220 brpA K Transcriptional
EMCNNKKH_00807 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
EMCNNKKH_00808 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
EMCNNKKH_00809 1.9e-248 pbuO S permease
EMCNNKKH_00810 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
EMCNNKKH_00811 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
EMCNNKKH_00812 1.3e-174 manL 2.7.1.191 G pts system
EMCNNKKH_00813 7e-118 manM G pts system
EMCNNKKH_00814 1.9e-169 manN G PTS system mannose fructose sorbose family IID component
EMCNNKKH_00815 6.5e-63 manO S protein conserved in bacteria
EMCNNKKH_00816 1.5e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EMCNNKKH_00817 2.2e-51 devA 3.6.3.25 V abc transporter atp-binding protein
EMCNNKKH_00818 1.1e-151 V MatE
EMCNNKKH_00820 1.5e-109 C Fe-S oxidoreductases
EMCNNKKH_00821 1.2e-176 EGP Major Facilitator Superfamily
EMCNNKKH_00822 5.5e-258 I radical SAM domain protein
EMCNNKKH_00824 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EMCNNKKH_00825 1.4e-150 L Integrase core domain protein
EMCNNKKH_00826 1.8e-87 L transposase activity
EMCNNKKH_00828 1.5e-61
EMCNNKKH_00829 0.0 sbcC L ATPase involved in DNA repair
EMCNNKKH_00830 5.3e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
EMCNNKKH_00831 0.0 lacL 3.2.1.23 G -beta-galactosidase
EMCNNKKH_00832 0.0 lacS G transporter
EMCNNKKH_00833 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
EMCNNKKH_00834 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EMCNNKKH_00835 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
EMCNNKKH_00836 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EMCNNKKH_00837 1.8e-184 galR K Transcriptional regulator
EMCNNKKH_00838 2.7e-08 L Integrase core domain protein
EMCNNKKH_00839 1.2e-25 L transposition
EMCNNKKH_00840 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
EMCNNKKH_00841 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
EMCNNKKH_00842 2.5e-101 V abc transporter atp-binding protein
EMCNNKKH_00843 4.3e-40 V abc transporter atp-binding protein
EMCNNKKH_00844 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
EMCNNKKH_00845 3.3e-62 rplQ J ribosomal protein l17
EMCNNKKH_00846 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EMCNNKKH_00847 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EMCNNKKH_00848 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EMCNNKKH_00849 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EMCNNKKH_00850 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EMCNNKKH_00851 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EMCNNKKH_00852 2.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EMCNNKKH_00853 4.4e-58 rplO J binds to the 23S rRNA
EMCNNKKH_00854 2.5e-23 rpmD J ribosomal protein l30
EMCNNKKH_00855 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EMCNNKKH_00856 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EMCNNKKH_00857 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EMCNNKKH_00858 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EMCNNKKH_00859 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EMCNNKKH_00860 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EMCNNKKH_00861 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EMCNNKKH_00862 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EMCNNKKH_00863 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EMCNNKKH_00864 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
EMCNNKKH_00865 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EMCNNKKH_00866 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EMCNNKKH_00867 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EMCNNKKH_00868 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EMCNNKKH_00869 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EMCNNKKH_00870 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EMCNNKKH_00871 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
EMCNNKKH_00872 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EMCNNKKH_00873 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
EMCNNKKH_00874 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EMCNNKKH_00875 0.0 XK27_09800 I Acyltransferase
EMCNNKKH_00876 1.7e-35 XK27_09805 S MORN repeat protein
EMCNNKKH_00877 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EMCNNKKH_00878 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EMCNNKKH_00879 8.8e-83 adk 2.7.4.3 F topology modulation protein
EMCNNKKH_00880 3.1e-172 yxaM EGP Major facilitator Superfamily
EMCNNKKH_00881 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
EMCNNKKH_00882 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
EMCNNKKH_00883 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
EMCNNKKH_00884 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EMCNNKKH_00885 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EMCNNKKH_00888 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EMCNNKKH_00889 5.8e-175 vraS 2.7.13.3 T Histidine kinase
EMCNNKKH_00890 3.7e-120 yvqF KT membrane
EMCNNKKH_00891 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
EMCNNKKH_00892 9e-133 stp 3.1.3.16 T phosphatase
EMCNNKKH_00893 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EMCNNKKH_00894 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EMCNNKKH_00895 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EMCNNKKH_00896 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
EMCNNKKH_00897 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
EMCNNKKH_00898 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EMCNNKKH_00899 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
EMCNNKKH_00900 2.1e-148 supH S overlaps another CDS with the same product name
EMCNNKKH_00901 8.6e-63 yvoA_1 K Transcriptional
EMCNNKKH_00902 9.8e-121 skfE V abc transporter atp-binding protein
EMCNNKKH_00903 5.6e-133 V ATPase activity
EMCNNKKH_00904 1.4e-56 oppF P Belongs to the ABC transporter superfamily
EMCNNKKH_00905 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
EMCNNKKH_00906 1.8e-57 asp S cog cog1302
EMCNNKKH_00907 3.2e-226 norN V Mate efflux family protein
EMCNNKKH_00908 9.2e-278 thrC 4.2.3.1 E Threonine synthase
EMCNNKKH_00909 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EMCNNKKH_00910 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
EMCNNKKH_00911 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EMCNNKKH_00912 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EMCNNKKH_00913 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
EMCNNKKH_00914 0.0 pepO 3.4.24.71 O Peptidase family M13
EMCNNKKH_00915 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EMCNNKKH_00916 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EMCNNKKH_00917 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
EMCNNKKH_00918 1.4e-54 treB 2.7.1.201 G PTS System
EMCNNKKH_00919 5.8e-21 treR K DNA-binding transcription factor activity
EMCNNKKH_00920 1.2e-85 treR K trehalose operon
EMCNNKKH_00921 3.3e-95 ywlG S Belongs to the UPF0340 family
EMCNNKKH_00923 1.8e-127 tnp L Transposase
EMCNNKKH_00924 2e-20 S phage tail
EMCNNKKH_00925 7.1e-130 S EcsC protein family
EMCNNKKH_00926 2.4e-23 S phage tail tape measure protein
EMCNNKKH_00927 9.8e-71 L Phage integrase family
EMCNNKKH_00929 4.2e-72 L PFAM Integrase, catalytic core
EMCNNKKH_00930 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
EMCNNKKH_00932 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
EMCNNKKH_00933 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
EMCNNKKH_00934 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
EMCNNKKH_00935 3.3e-09 L PFAM Integrase, catalytic core
EMCNNKKH_00936 1.4e-96 V VanZ like family
EMCNNKKH_00937 7.6e-70 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
EMCNNKKH_00938 3.5e-29 G Belongs to the phosphoglycerate mutase family
EMCNNKKH_00939 3.9e-61 G Belongs to the phosphoglycerate mutase family
EMCNNKKH_00940 1.3e-199 S hmm pf01594
EMCNNKKH_00941 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EMCNNKKH_00942 3.5e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EMCNNKKH_00943 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EMCNNKKH_00944 4.9e-39 S granule-associated protein
EMCNNKKH_00945 2e-294 S unusual protein kinase
EMCNNKKH_00946 2.6e-15 estA E Lysophospholipase L1 and related esterases
EMCNNKKH_00947 6.1e-79 estA E GDSL-like protein
EMCNNKKH_00948 1.3e-159 rssA S Phospholipase, patatin family
EMCNNKKH_00949 1.3e-125 3.4.16.4 M Belongs to the peptidase S11 family
EMCNNKKH_00950 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
EMCNNKKH_00951 3.8e-17 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
EMCNNKKH_00952 3e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EMCNNKKH_00953 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EMCNNKKH_00954 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EMCNNKKH_00955 4.4e-66 S the current gene model (or a revised gene model) may contain a frame shift
EMCNNKKH_00956 1.1e-37 P membrane protein (DUF2207)
EMCNNKKH_00957 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
EMCNNKKH_00958 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
EMCNNKKH_00959 3.5e-28 3.4.13.21 I Protein conserved in bacteria
EMCNNKKH_00960 8.1e-90 FNV0100 F Belongs to the Nudix hydrolase family
EMCNNKKH_00961 3.7e-190
EMCNNKKH_00962 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
EMCNNKKH_00964 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
EMCNNKKH_00965 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
EMCNNKKH_00966 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
EMCNNKKH_00967 1.2e-143 2.4.2.3 F Phosphorylase superfamily
EMCNNKKH_00970 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
EMCNNKKH_00971 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
EMCNNKKH_00972 6e-08 S Hydrolases of the alpha beta superfamily
EMCNNKKH_00973 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
EMCNNKKH_00974 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
EMCNNKKH_00975 1.8e-159 czcD P cation diffusion facilitator family transporter
EMCNNKKH_00976 9e-98 K Transcriptional regulator, TetR family
EMCNNKKH_00977 1.6e-10
EMCNNKKH_00978 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
EMCNNKKH_00979 6.4e-104 V ABC transporter (Permease
EMCNNKKH_00981 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EMCNNKKH_00982 0.0 KLT serine threonine protein kinase
EMCNNKKH_00983 2.1e-280 V ABC transporter
EMCNNKKH_00984 1.4e-127 Z012_04635 K sequence-specific DNA binding
EMCNNKKH_00986 3.4e-191 C Radical SAM
EMCNNKKH_00987 3.9e-287 V ABC transporter transmembrane region
EMCNNKKH_00988 1.7e-90 K sequence-specific DNA binding
EMCNNKKH_00989 1e-36 L Replication initiation factor
EMCNNKKH_00990 1.4e-107 L Replication initiation factor
EMCNNKKH_00991 1.9e-18 S Domain of unknown function (DUF3173)
EMCNNKKH_00992 3.5e-216 int L Belongs to the 'phage' integrase family
EMCNNKKH_00994 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
EMCNNKKH_00995 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
EMCNNKKH_00996 2.8e-44 yrzL S Belongs to the UPF0297 family
EMCNNKKH_00997 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EMCNNKKH_00998 4.2e-44 yrzB S Belongs to the UPF0473 family
EMCNNKKH_00999 1.4e-54
EMCNNKKH_01000 0.0 ctpE P E1-E2 ATPase
EMCNNKKH_01001 3.9e-26
EMCNNKKH_01002 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EMCNNKKH_01003 5.1e-47 L transposase activity
EMCNNKKH_01004 1.4e-81 K transcriptional regulator, MerR family
EMCNNKKH_01005 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
EMCNNKKH_01006 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
EMCNNKKH_01007 7.4e-64 XK27_02560 S cog cog2151
EMCNNKKH_01008 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
EMCNNKKH_01009 7.7e-227 ytfP S Flavoprotein
EMCNNKKH_01011 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EMCNNKKH_01012 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
EMCNNKKH_01013 2.7e-183 ecsB U ABC transporter
EMCNNKKH_01014 2.3e-133 ecsA V abc transporter atp-binding protein
EMCNNKKH_01015 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
EMCNNKKH_01016 6e-11
EMCNNKKH_01017 1.3e-56 S CD20-like family
EMCNNKKH_01018 3.2e-110
EMCNNKKH_01019 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
EMCNNKKH_01020 6.9e-206 ylbM S Belongs to the UPF0348 family
EMCNNKKH_01021 2e-140 yqeM Q Methyltransferase domain protein
EMCNNKKH_01022 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EMCNNKKH_01023 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
EMCNNKKH_01024 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EMCNNKKH_01025 3.5e-49 yhbY J RNA-binding protein
EMCNNKKH_01026 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
EMCNNKKH_01027 1.8e-98 yqeG S hydrolase of the HAD superfamily
EMCNNKKH_01028 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
EMCNNKKH_01029 5.8e-24
EMCNNKKH_01030 3.5e-13
EMCNNKKH_01031 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EMCNNKKH_01032 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EMCNNKKH_01033 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EMCNNKKH_01034 1.3e-251 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
EMCNNKKH_01035 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EMCNNKKH_01036 1.6e-154 hlpA M Belongs to the NlpA lipoprotein family
EMCNNKKH_01037 6.8e-101 pncA Q isochorismatase
EMCNNKKH_01038 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EMCNNKKH_01039 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
EMCNNKKH_01040 2.4e-75 XK27_03180 T universal stress protein
EMCNNKKH_01043 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EMCNNKKH_01044 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
EMCNNKKH_01045 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
EMCNNKKH_01046 0.0 yjcE P NhaP-type Na H and K H antiporters
EMCNNKKH_01048 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
EMCNNKKH_01049 1.3e-184 yhcC S radical SAM protein
EMCNNKKH_01050 2.2e-196 ylbL T Belongs to the peptidase S16 family
EMCNNKKH_01051 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EMCNNKKH_01052 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
EMCNNKKH_01053 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EMCNNKKH_01054 1.9e-09 S Protein of unknown function (DUF4059)
EMCNNKKH_01055 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
EMCNNKKH_01056 4.7e-163 yxeN P ABC transporter (Permease
EMCNNKKH_01057 1.2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EMCNNKKH_01059 1.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EMCNNKKH_01060 0.0 pflB 2.3.1.54 C formate acetyltransferase'
EMCNNKKH_01061 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
EMCNNKKH_01062 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EMCNNKKH_01063 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
EMCNNKKH_01064 2.9e-87 D nuclear chromosome segregation
EMCNNKKH_01065 1.5e-127 ybbM S transport system, permease component
EMCNNKKH_01066 1.2e-117 ybbL S abc transporter atp-binding protein
EMCNNKKH_01067 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
EMCNNKKH_01068 4.6e-140 cppA E CppA N-terminal
EMCNNKKH_01069 5e-44 V CAAX protease self-immunity
EMCNNKKH_01070 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EMCNNKKH_01071 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
EMCNNKKH_01074 3e-47 spiA K sequence-specific DNA binding
EMCNNKKH_01075 2.9e-28 blpT
EMCNNKKH_01076 6.7e-98 blpT
EMCNNKKH_01083 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
EMCNNKKH_01087 7.4e-135 agrA KT phosphorelay signal transduction system
EMCNNKKH_01088 3.4e-239 blpH 2.7.13.3 T protein histidine kinase activity
EMCNNKKH_01090 7.3e-237 mesE M Transport protein ComB
EMCNNKKH_01091 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EMCNNKKH_01092 0.0 mdlB V abc transporter atp-binding protein
EMCNNKKH_01093 9.1e-303 mdlA V abc transporter atp-binding protein
EMCNNKKH_01095 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
EMCNNKKH_01096 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EMCNNKKH_01097 3.6e-70 yutD J protein conserved in bacteria
EMCNNKKH_01098 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
EMCNNKKH_01100 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
EMCNNKKH_01101 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EMCNNKKH_01102 0.0 ftsI 3.4.16.4 M penicillin-binding protein
EMCNNKKH_01103 4.3e-47 ftsL D cell division protein FtsL
EMCNNKKH_01104 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EMCNNKKH_01105 1.6e-65
EMCNNKKH_01106 7.4e-27
EMCNNKKH_01107 2.6e-30
EMCNNKKH_01109 9.7e-32 yhaI J Protein of unknown function (DUF805)
EMCNNKKH_01110 1.3e-08 D nuclear chromosome segregation
EMCNNKKH_01111 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EMCNNKKH_01112 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EMCNNKKH_01113 6.2e-288 XK27_00765
EMCNNKKH_01114 1.4e-133 ecsA_2 V abc transporter atp-binding protein
EMCNNKKH_01115 2.5e-47 S Protein of unknown function (DUF554)
EMCNNKKH_01116 8.5e-32 S Protein of unknown function (DUF554)
EMCNNKKH_01117 1.6e-11 S Protein of unknown function (DUF554)
EMCNNKKH_01118 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
EMCNNKKH_01119 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
EMCNNKKH_01120 2.6e-121 liaI S membrane
EMCNNKKH_01121 5.2e-75 XK27_02470 K LytTr DNA-binding domain
EMCNNKKH_01122 3.6e-66 KT response to antibiotic
EMCNNKKH_01123 2.6e-80 yebC M Membrane
EMCNNKKH_01124 2.9e-18 yebC M Membrane
EMCNNKKH_01125 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
EMCNNKKH_01126 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
EMCNNKKH_01128 0.0
EMCNNKKH_01130 1.5e-35 K sequence-specific DNA binding
EMCNNKKH_01131 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
EMCNNKKH_01132 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EMCNNKKH_01133 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EMCNNKKH_01134 1.8e-31 K helix-turn-helix
EMCNNKKH_01135 3.4e-155 degV S DegV family
EMCNNKKH_01136 3.5e-91 yacP S RNA-binding protein containing a PIN domain
EMCNNKKH_01137 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMCNNKKH_01140 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
EMCNNKKH_01141 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
EMCNNKKH_01142 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
EMCNNKKH_01143 6.9e-144 S SseB protein N-terminal domain
EMCNNKKH_01144 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EMCNNKKH_01145 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
EMCNNKKH_01146 9e-08
EMCNNKKH_01147 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
EMCNNKKH_01148 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
EMCNNKKH_01149 3.1e-81 ypmB S Protein conserved in bacteria
EMCNNKKH_01150 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
EMCNNKKH_01151 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
EMCNNKKH_01152 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
EMCNNKKH_01153 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
EMCNNKKH_01154 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
EMCNNKKH_01155 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
EMCNNKKH_01156 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
EMCNNKKH_01157 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EMCNNKKH_01158 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EMCNNKKH_01159 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EMCNNKKH_01160 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
EMCNNKKH_01161 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
EMCNNKKH_01162 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
EMCNNKKH_01163 2.1e-30 rpsT J rRNA binding
EMCNNKKH_01164 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
EMCNNKKH_01165 3.1e-10 L thioesterase
EMCNNKKH_01166 7.8e-143 S Macro domain protein
EMCNNKKH_01167 4.8e-51 trxA O Belongs to the thioredoxin family
EMCNNKKH_01168 2.5e-26 yccU S CoA-binding protein
EMCNNKKH_01169 1.4e-144 tatD L Hydrolase, tatd
EMCNNKKH_01170 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
EMCNNKKH_01171 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EMCNNKKH_01173 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
EMCNNKKH_01174 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
EMCNNKKH_01175 1.8e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
EMCNNKKH_01176 6.9e-173 rmuC S RmuC domain protein
EMCNNKKH_01177 1.8e-178 cbf S 3'-5' exoribonuclease yhaM
EMCNNKKH_01178 1.1e-142 purR 2.4.2.7 F operon repressor
EMCNNKKH_01179 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EMCNNKKH_01180 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EMCNNKKH_01181 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EMCNNKKH_01182 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EMCNNKKH_01183 5.7e-91 tnp L Transposase
EMCNNKKH_01184 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
EMCNNKKH_01185 4.3e-109 capA M Bacterial capsule synthesis protein
EMCNNKKH_01186 1.5e-55 capA M Bacterial capsule synthesis protein
EMCNNKKH_01187 3.6e-39 gcvR T UPF0237 protein
EMCNNKKH_01188 1.7e-243 XK27_08635 S UPF0210 protein
EMCNNKKH_01189 2.4e-135 ais G Phosphoglycerate mutase
EMCNNKKH_01190 2.1e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
EMCNNKKH_01191 1.3e-102 acmA 3.2.1.17 NU amidase activity
EMCNNKKH_01192 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EMCNNKKH_01193 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EMCNNKKH_01194 7.5e-298 dnaK O Heat shock 70 kDa protein
EMCNNKKH_01195 3.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EMCNNKKH_01196 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EMCNNKKH_01197 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
EMCNNKKH_01198 3.8e-31 hmpT S membrane
EMCNNKKH_01199 1.1e-29 yyzM S Protein conserved in bacteria
EMCNNKKH_01200 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EMCNNKKH_01201 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EMCNNKKH_01202 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EMCNNKKH_01203 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
EMCNNKKH_01204 2.7e-61 divIC D Septum formation initiator
EMCNNKKH_01206 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
EMCNNKKH_01207 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EMCNNKKH_01208 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EMCNNKKH_01209 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EMCNNKKH_01210 2.4e-164 L Transposase
EMCNNKKH_01211 4.4e-37 L Transposase
EMCNNKKH_01212 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
EMCNNKKH_01213 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
EMCNNKKH_01214 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EMCNNKKH_01215 4.9e-227 pyrP F uracil Permease
EMCNNKKH_01216 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EMCNNKKH_01217 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EMCNNKKH_01218 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EMCNNKKH_01219 1.8e-167 fhuR K transcriptional regulator (lysR family)
EMCNNKKH_01224 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
EMCNNKKH_01225 8.7e-259 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EMCNNKKH_01226 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
EMCNNKKH_01227 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EMCNNKKH_01228 8.5e-134 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
EMCNNKKH_01229 1.4e-101 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
EMCNNKKH_01230 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EMCNNKKH_01231 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EMCNNKKH_01232 3.2e-74 copY K Copper transport repressor, CopY TcrY family
EMCNNKKH_01233 0.0 copA 3.6.3.54 P P-type ATPase
EMCNNKKH_01234 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
EMCNNKKH_01235 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EMCNNKKH_01236 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
EMCNNKKH_01237 3.1e-268 clcA P Chloride transporter, ClC family
EMCNNKKH_01238 8.9e-206 potD P spermidine putrescine ABC transporter
EMCNNKKH_01239 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
EMCNNKKH_01240 1e-190 L Transposase
EMCNNKKH_01241 5.1e-117 mur1 NU muramidase
EMCNNKKH_01242 1.2e-172 yeiH S Membrane
EMCNNKKH_01244 1.7e-08
EMCNNKKH_01245 9.2e-297 adcA P Belongs to the bacterial solute-binding protein 9 family
EMCNNKKH_01246 2.2e-101 XK27_10720 D peptidase activity
EMCNNKKH_01247 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
EMCNNKKH_01248 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
EMCNNKKH_01249 3.7e-157 glcU U Glucose uptake
EMCNNKKH_01250 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
EMCNNKKH_01251 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
EMCNNKKH_01252 3.7e-44 L Transposase
EMCNNKKH_01253 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
EMCNNKKH_01254 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EMCNNKKH_01255 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
EMCNNKKH_01256 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
EMCNNKKH_01257 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
EMCNNKKH_01258 7.7e-20 D nuclear chromosome segregation
EMCNNKKH_01259 7.4e-138 yejC S cyclic nucleotide-binding protein
EMCNNKKH_01260 1.2e-163 rapZ S Displays ATPase and GTPase activities
EMCNNKKH_01261 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
EMCNNKKH_01262 8.7e-162 whiA K May be required for sporulation
EMCNNKKH_01263 2.8e-90 pepD E Dipeptidase
EMCNNKKH_01264 5.8e-41 pepD E dipeptidase activity
EMCNNKKH_01265 5.4e-32 cspD K Cold shock protein domain
EMCNNKKH_01266 9.4e-43 K Cold-Shock Protein
EMCNNKKH_01267 9.9e-94 serB 3.1.3.3 E phosphoserine phosphatase
EMCNNKKH_01268 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
EMCNNKKH_01269 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMCNNKKH_01270 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMCNNKKH_01271 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
EMCNNKKH_01273 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
EMCNNKKH_01274 4.7e-51 ycaO O OsmC-like protein
EMCNNKKH_01275 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
EMCNNKKH_01278 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EMCNNKKH_01280 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EMCNNKKH_01281 1.1e-16 XK27_00735
EMCNNKKH_01282 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
EMCNNKKH_01283 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
EMCNNKKH_01284 2.4e-33 S CAAX amino terminal protease family protein
EMCNNKKH_01285 2.5e-56 V CAAX protease self-immunity
EMCNNKKH_01286 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EMCNNKKH_01287 2.9e-84 mutT 3.6.1.55 F Nudix family
EMCNNKKH_01288 7.5e-144 ET Belongs to the bacterial solute-binding protein 3 family
EMCNNKKH_01289 6.5e-137 ET ABC transporter
EMCNNKKH_01290 1.6e-202 arcT 2.6.1.1 E Aminotransferase
EMCNNKKH_01291 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
EMCNNKKH_01292 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
EMCNNKKH_01293 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EMCNNKKH_01294 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EMCNNKKH_01295 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
EMCNNKKH_01296 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
EMCNNKKH_01297 5.3e-237 S Predicted membrane protein (DUF2142)
EMCNNKKH_01298 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EMCNNKKH_01299 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
EMCNNKKH_01300 9.3e-186 S Glycosyltransferase like family 2
EMCNNKKH_01301 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
EMCNNKKH_01302 6.9e-130 arnC M group 2 family protein
EMCNNKKH_01303 4.6e-42 S Uncharacterized conserved protein (DUF2304)
EMCNNKKH_01304 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
EMCNNKKH_01305 1.8e-228 rgpA GT4 M Domain of unknown function (DUF1972)
EMCNNKKH_01306 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
EMCNNKKH_01307 2.1e-143 rgpC GM Transport permease protein
EMCNNKKH_01308 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
EMCNNKKH_01309 2e-305 GT4 M transferase activity, transferring glycosyl groups
EMCNNKKH_01310 0.0 rgpF M Rhamnan synthesis protein F
EMCNNKKH_01311 1.7e-268 M Psort location CytoplasmicMembrane, score
EMCNNKKH_01312 1.2e-115 radC E Belongs to the UPF0758 family
EMCNNKKH_01313 7.2e-132 puuD T peptidase C26
EMCNNKKH_01314 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
EMCNNKKH_01315 3.1e-59 XK27_04120 S Putative amino acid metabolism
EMCNNKKH_01316 2.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
EMCNNKKH_01317 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EMCNNKKH_01318 1.5e-103 yjbK S Adenylate cyclase
EMCNNKKH_01319 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
EMCNNKKH_01320 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EMCNNKKH_01321 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EMCNNKKH_01322 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EMCNNKKH_01323 1.4e-66 L transposition
EMCNNKKH_01324 2.6e-166 cpsY K Transcriptional regulator
EMCNNKKH_01325 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EMCNNKKH_01326 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
EMCNNKKH_01327 2.4e-105 artQ P ABC transporter (Permease
EMCNNKKH_01328 1.8e-113 glnQ 3.6.3.21 E abc transporter atp-binding protein
EMCNNKKH_01329 1.1e-158 aatB ET ABC transporter substrate-binding protein
EMCNNKKH_01330 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EMCNNKKH_01331 2.1e-07
EMCNNKKH_01332 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
EMCNNKKH_01333 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
EMCNNKKH_01334 1.1e-19 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
EMCNNKKH_01335 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EMCNNKKH_01336 2e-126 gntR1 K transcriptional
EMCNNKKH_01337 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
EMCNNKKH_01338 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EMCNNKKH_01339 2.4e-87 niaX
EMCNNKKH_01340 6e-91 niaR S small molecule binding protein (contains 3H domain)
EMCNNKKH_01341 9.6e-129 K DNA-binding helix-turn-helix protein
EMCNNKKH_01342 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EMCNNKKH_01343 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EMCNNKKH_01344 8.2e-168 GK ROK family
EMCNNKKH_01345 8.3e-159 dprA LU DNA protecting protein DprA
EMCNNKKH_01346 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EMCNNKKH_01347 3.6e-154 S TraX protein
EMCNNKKH_01348 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EMCNNKKH_01349 1.3e-249 T PhoQ Sensor
EMCNNKKH_01350 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EMCNNKKH_01351 1.1e-152 XK27_05470 E Methionine synthase
EMCNNKKH_01352 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
EMCNNKKH_01353 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EMCNNKKH_01354 1.8e-51 IQ Acetoin reductase
EMCNNKKH_01355 3.9e-19 IQ Acetoin reductase
EMCNNKKH_01356 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EMCNNKKH_01357 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
EMCNNKKH_01360 1.3e-212 pqqE C radical SAM domain protein
EMCNNKKH_01361 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
EMCNNKKH_01362 6.6e-61 EGP Major facilitator Superfamily
EMCNNKKH_01363 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
EMCNNKKH_01364 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
EMCNNKKH_01365 2.4e-178 L transposase, IS4 family
EMCNNKKH_01366 3e-13 mesE M Transport protein ComB
EMCNNKKH_01367 0.0 P Belongs to the ABC transporter superfamily
EMCNNKKH_01368 1.8e-141 dppC P N-terminal TM domain of oligopeptide transport permease C
EMCNNKKH_01369 2.8e-188 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
EMCNNKKH_01370 0.0 ddpA E ABC transporter substrate-binding protein
EMCNNKKH_01372 1.9e-57 L Transposase
EMCNNKKH_01373 3.5e-97 S reductase
EMCNNKKH_01374 2.6e-55 badR K DNA-binding transcription factor activity
EMCNNKKH_01375 1.9e-36 XK27_02060 S Transglycosylase associated protein
EMCNNKKH_01376 2.3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
EMCNNKKH_01377 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EMCNNKKH_01382 1.9e-07
EMCNNKKH_01385 2.6e-10
EMCNNKKH_01386 2.2e-204 oppD P Belongs to the ABC transporter superfamily
EMCNNKKH_01387 4.9e-168 amiD P ABC transporter (Permease
EMCNNKKH_01388 4.2e-278 amiC P ABC transporter (Permease
EMCNNKKH_01389 0.0 amiA E ABC transporter, substrate-binding protein, family 5
EMCNNKKH_01391 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
EMCNNKKH_01392 0.0 3.6.3.8 P cation transport ATPase
EMCNNKKH_01393 1.5e-194 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EMCNNKKH_01394 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
EMCNNKKH_01395 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
EMCNNKKH_01396 2.6e-95 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
EMCNNKKH_01397 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
EMCNNKKH_01398 3.6e-35 V efflux transmembrane transporter activity
EMCNNKKH_01399 3.1e-31 V efflux transmembrane transporter activity
EMCNNKKH_01400 8.2e-28 ytrF V efflux transmembrane transporter activity
EMCNNKKH_01401 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EMCNNKKH_01402 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EMCNNKKH_01403 1.8e-63 L Transposase
EMCNNKKH_01404 4.1e-158 L COG2801 Transposase and inactivated derivatives
EMCNNKKH_01405 8.1e-45 L Transposase
EMCNNKKH_01406 2.1e-163 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
EMCNNKKH_01407 0.0 lpdA 1.8.1.4 C Dehydrogenase
EMCNNKKH_01408 6.4e-11 3.5.1.28 NU amidase activity
EMCNNKKH_01409 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
EMCNNKKH_01410 8.6e-187 3.5.1.28 M GBS Bsp-like repeat
EMCNNKKH_01411 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EMCNNKKH_01412 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EMCNNKKH_01413 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EMCNNKKH_01414 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EMCNNKKH_01415 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
EMCNNKKH_01416 1e-165 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EMCNNKKH_01417 5.6e-167 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EMCNNKKH_01418 6.8e-136 yclP 3.6.3.34 P abc transporter atp-binding protein
EMCNNKKH_01419 2e-178 fatB P ABC-type enterochelin transport system, periplasmic component
EMCNNKKH_01420 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
EMCNNKKH_01421 8.7e-234 ycdB P peroxidase
EMCNNKKH_01422 7.2e-303 ywbL P COG0672 High-affinity Fe2 Pb2 permease
EMCNNKKH_01423 9e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EMCNNKKH_01424 4.6e-25 tatA U protein secretion
EMCNNKKH_01425 2.3e-23 L Transposase
EMCNNKKH_01426 1.2e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
EMCNNKKH_01427 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EMCNNKKH_01430 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
EMCNNKKH_01431 8.3e-196 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
EMCNNKKH_01432 0.0 pepN 3.4.11.2 E aminopeptidase
EMCNNKKH_01433 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
EMCNNKKH_01434 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EMCNNKKH_01435 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EMCNNKKH_01436 1.2e-155 pstA P phosphate transport system permease
EMCNNKKH_01437 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
EMCNNKKH_01438 3.3e-158 pstS P phosphate
EMCNNKKH_01439 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
EMCNNKKH_01440 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
EMCNNKKH_01441 1.9e-43 yktA S Belongs to the UPF0223 family
EMCNNKKH_01442 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
EMCNNKKH_01443 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
EMCNNKKH_01444 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EMCNNKKH_01445 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
EMCNNKKH_01446 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
EMCNNKKH_01447 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
EMCNNKKH_01448 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EMCNNKKH_01449 9.3e-62 S haloacid dehalogenase-like hydrolase
EMCNNKKH_01450 1.8e-59 Q phosphatase activity
EMCNNKKH_01451 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
EMCNNKKH_01452 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
EMCNNKKH_01453 1.8e-240 agcS E (Alanine) symporter
EMCNNKKH_01454 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EMCNNKKH_01455 4e-99 yfiF3 K sequence-specific DNA binding
EMCNNKKH_01456 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
EMCNNKKH_01457 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
EMCNNKKH_01459 2.3e-20 yecS P amino acid transport
EMCNNKKH_01460 1.4e-62 yecS P ABC transporter (Permease
EMCNNKKH_01461 1.6e-266 dtpT E transporter
EMCNNKKH_01462 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EMCNNKKH_01463 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
EMCNNKKH_01464 9.5e-32 csm6 S Psort location Cytoplasmic, score
EMCNNKKH_01466 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
EMCNNKKH_01467 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
EMCNNKKH_01468 1.6e-117 csm3 L RAMP superfamily
EMCNNKKH_01469 2.5e-62 csm2 L Csm2 Type III-A
EMCNNKKH_01470 1.2e-210 csm1 S CRISPR-associated protein Csm1 family
EMCNNKKH_01471 1.1e-204 csm1 S CRISPR-associated protein Csm1 family
EMCNNKKH_01472 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
EMCNNKKH_01473 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMCNNKKH_01474 6e-188 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EMCNNKKH_01475 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EMCNNKKH_01476 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
EMCNNKKH_01477 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
EMCNNKKH_01478 4.3e-118 S TraX protein
EMCNNKKH_01480 3e-44 ymbI L transposase activity
EMCNNKKH_01481 4e-22 L Belongs to the 'phage' integrase family
EMCNNKKH_01482 1.4e-66 S tRNA_anti-like
EMCNNKKH_01483 2e-103
EMCNNKKH_01485 5e-12
EMCNNKKH_01487 2e-296 S DNA primase
EMCNNKKH_01488 3e-164 KL Phage plasmid primase P4 family
EMCNNKKH_01489 6.9e-22
EMCNNKKH_01490 9.2e-13
EMCNNKKH_01495 1.3e-17 K Cro/C1-type HTH DNA-binding domain
EMCNNKKH_01497 1.1e-220 sip L Belongs to the 'phage' integrase family
EMCNNKKH_01499 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EMCNNKKH_01500 7.3e-166 metF 1.5.1.20 E reductase
EMCNNKKH_01501 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
EMCNNKKH_01502 1.7e-94 panT S ECF transporter, substrate-specific component
EMCNNKKH_01503 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EMCNNKKH_01504 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
EMCNNKKH_01505 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
EMCNNKKH_01506 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EMCNNKKH_01507 2.8e-40 T PhoQ Sensor
EMCNNKKH_01508 1.7e-43 T PhoQ Sensor
EMCNNKKH_01509 5.8e-79 T PhoQ Sensor
EMCNNKKH_01510 1e-110 L Integrase core domain protein
EMCNNKKH_01511 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
EMCNNKKH_01512 1.4e-40 tatD L Hydrolase, tatd
EMCNNKKH_01513 2.4e-214 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EMCNNKKH_01514 1.9e-225 nodC 2.4.1.212 GT2 M Chitin synthase
EMCNNKKH_01515 0.0 copB 3.6.3.4 P P-type ATPase
EMCNNKKH_01516 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
EMCNNKKH_01517 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
EMCNNKKH_01518 1.4e-92 3.6.4.12 K Divergent AAA domain protein
EMCNNKKH_01519 5.9e-24 3.6.4.12
EMCNNKKH_01520 7.7e-112 EGP Major facilitator Superfamily
EMCNNKKH_01521 4.7e-56 EGP Major facilitator Superfamily
EMCNNKKH_01522 3e-246 cps1C S Polysaccharide biosynthesis protein
EMCNNKKH_01523 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
EMCNNKKH_01524 1.6e-18 L Integrase core domain
EMCNNKKH_01527 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
EMCNNKKH_01528 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
EMCNNKKH_01530 3.2e-17 S Domain of unknown function (DUF4649)
EMCNNKKH_01531 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
EMCNNKKH_01532 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
EMCNNKKH_01533 1.2e-135 XK27_08845 S abc transporter atp-binding protein
EMCNNKKH_01534 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EMCNNKKH_01535 9.2e-152 estA CE1 S Putative esterase
EMCNNKKH_01536 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
EMCNNKKH_01537 5.5e-14 XK27_08880
EMCNNKKH_01538 2.3e-75 fld C Flavodoxin
EMCNNKKH_01539 6.4e-282 clcA P Chloride transporter, ClC family
EMCNNKKH_01540 5.1e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
EMCNNKKH_01541 3.2e-220 XK27_05110 P chloride
EMCNNKKH_01542 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EMCNNKKH_01545 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
EMCNNKKH_01546 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EMCNNKKH_01547 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
EMCNNKKH_01548 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EMCNNKKH_01549 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
EMCNNKKH_01550 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EMCNNKKH_01551 0.0 5.1.3.2 GM Psort location CytoplasmicMembrane, score
EMCNNKKH_01552 2.2e-168
EMCNNKKH_01553 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
EMCNNKKH_01554 4.3e-277 pelF GT4 M Domain of unknown function (DUF3492)
EMCNNKKH_01555 3.8e-199 pelG M Putative exopolysaccharide Exporter (EPS-E)
EMCNNKKH_01556 2.3e-49 pelG S Putative exopolysaccharide Exporter (EPS-E)
EMCNNKKH_01557 1.5e-211 cotH M CotH kinase protein
EMCNNKKH_01558 8.4e-53 G Domain of unknown function (DUF4832)
EMCNNKKH_01559 2.2e-21 G Domain of unknown function (DUF4832)
EMCNNKKH_01560 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EMCNNKKH_01562 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EMCNNKKH_01563 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
EMCNNKKH_01564 2.4e-124 endA F DNA RNA non-specific endonuclease
EMCNNKKH_01565 1.7e-111 tcyB_2 P ABC transporter (permease)
EMCNNKKH_01566 5.9e-118 gltJ P ABC transporter (Permease
EMCNNKKH_01567 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
EMCNNKKH_01568 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
EMCNNKKH_01569 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EMCNNKKH_01570 1.5e-247 vicK 2.7.13.3 T Histidine kinase
EMCNNKKH_01571 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
EMCNNKKH_01572 1.8e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
EMCNNKKH_01573 1.2e-146 yidA S hydrolases of the HAD superfamily
EMCNNKKH_01574 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
EMCNNKKH_01575 2.6e-67 ywiB S Domain of unknown function (DUF1934)
EMCNNKKH_01576 0.0 pacL 3.6.3.8 P cation transport ATPase
EMCNNKKH_01577 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
EMCNNKKH_01578 1.1e-180 yjjH S Calcineurin-like phosphoesterase
EMCNNKKH_01579 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EMCNNKKH_01580 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EMCNNKKH_01581 2.5e-124 ftsE D cell division ATP-binding protein FtsE
EMCNNKKH_01582 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
EMCNNKKH_01583 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
EMCNNKKH_01584 6.2e-176 yubA S permease
EMCNNKKH_01585 3.7e-224 G COG0457 FOG TPR repeat
EMCNNKKH_01586 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EMCNNKKH_01587 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
EMCNNKKH_01588 2.9e-90 ebsA S Family of unknown function (DUF5322)
EMCNNKKH_01589 3.9e-15 M LysM domain
EMCNNKKH_01590 6.6e-122 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
EMCNNKKH_01591 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EMCNNKKH_01592 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
EMCNNKKH_01593 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EMCNNKKH_01594 4.7e-24 L Transposase
EMCNNKKH_01595 6.9e-86 XK27_03610 K Gnat family
EMCNNKKH_01596 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
EMCNNKKH_01597 2.1e-276 pepV 3.5.1.18 E Dipeptidase
EMCNNKKH_01598 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
EMCNNKKH_01599 6.1e-22 V Glucan-binding protein C
EMCNNKKH_01601 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EMCNNKKH_01602 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
EMCNNKKH_01603 8.1e-41 S Protein of unknown function (DUF1697)
EMCNNKKH_01604 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EMCNNKKH_01605 9.4e-66 clcA_2 P chloride
EMCNNKKH_01606 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
EMCNNKKH_01607 1.5e-30 yfeJ 6.3.5.2 F glutamine amidotransferase
EMCNNKKH_01608 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
EMCNNKKH_01609 8e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
EMCNNKKH_01610 4.6e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
EMCNNKKH_01611 1.9e-116 cps4C M biosynthesis protein
EMCNNKKH_01612 9.7e-119 cpsD D COG0489 ATPases involved in chromosome partitioning
EMCNNKKH_01613 2.4e-256 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
EMCNNKKH_01614 2.4e-31 rgpAc GT4 M Domain of unknown function (DUF1972)
EMCNNKKH_01615 3.3e-88 cpsF M Oligosaccharide biosynthesis protein Alg14 like
EMCNNKKH_01616 2e-91 pssE S Glycosyltransferase family 28 C-terminal domain
EMCNNKKH_01617 4.6e-202 GT4 M Glycosyltransferase, group 1 family protein
EMCNNKKH_01618 7.6e-174 rgpB GT2 S Glycosyl transferase family 2
EMCNNKKH_01619 5.8e-202 cps1B GT2,GT4 M Glycosyl transferases group 1
EMCNNKKH_01621 1.1e-183 M Glycosyltransferase, group 2 family protein
EMCNNKKH_01622 1.3e-22 XK27_08085
EMCNNKKH_01623 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EMCNNKKH_01624 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
EMCNNKKH_01625 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
EMCNNKKH_01626 1.1e-121 ylfI S tigr01906
EMCNNKKH_01627 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
EMCNNKKH_01628 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
EMCNNKKH_01629 1.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
EMCNNKKH_01632 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EMCNNKKH_01633 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
EMCNNKKH_01634 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EMCNNKKH_01635 1.6e-207 yurR 1.4.5.1 E oxidoreductase
EMCNNKKH_01636 6.4e-29 zupT P transporter
EMCNNKKH_01637 2.3e-14 zupT P Mediates zinc uptake. May also transport other divalent cations
EMCNNKKH_01638 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EMCNNKKH_01639 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
EMCNNKKH_01640 1.7e-70 gtrA S GtrA-like protein
EMCNNKKH_01641 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EMCNNKKH_01642 6e-169 ybbR S Protein conserved in bacteria
EMCNNKKH_01643 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EMCNNKKH_01644 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
EMCNNKKH_01645 8.7e-150 cobQ S glutamine amidotransferase
EMCNNKKH_01646 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EMCNNKKH_01647 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
EMCNNKKH_01648 0.0 uup S abc transporter atp-binding protein
EMCNNKKH_01649 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
EMCNNKKH_01650 9.3e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
EMCNNKKH_01651 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EMCNNKKH_01652 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
EMCNNKKH_01653 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EMCNNKKH_01654 7.9e-39 ptsH G phosphocarrier protein Hpr
EMCNNKKH_01655 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
EMCNNKKH_01656 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
EMCNNKKH_01657 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EMCNNKKH_01658 2.2e-34 nrdH O Glutaredoxin
EMCNNKKH_01659 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMCNNKKH_01660 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EMCNNKKH_01662 4.2e-71 L Transposase (IS116 IS110 IS902 family)
EMCNNKKH_01663 3.3e-26 L Transposase (IS116 IS110 IS902 family)
EMCNNKKH_01664 1.8e-165 ypuA S secreted protein
EMCNNKKH_01665 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
EMCNNKKH_01666 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
EMCNNKKH_01667 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EMCNNKKH_01668 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
EMCNNKKH_01669 3.4e-258 noxE P NADH oxidase
EMCNNKKH_01670 1.9e-294 yfmM S abc transporter atp-binding protein
EMCNNKKH_01671 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
EMCNNKKH_01672 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EMCNNKKH_01673 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
EMCNNKKH_01674 2e-86 S ECF-type riboflavin transporter, S component
EMCNNKKH_01676 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
EMCNNKKH_01677 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
EMCNNKKH_01679 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
EMCNNKKH_01680 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
EMCNNKKH_01681 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EMCNNKKH_01682 0.0 smc D Required for chromosome condensation and partitioning
EMCNNKKH_01683 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EMCNNKKH_01684 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EMCNNKKH_01685 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EMCNNKKH_01686 7.3e-82 alkD L Dna alkylation repair
EMCNNKKH_01687 2.8e-93 pat 2.3.1.183 M acetyltransferase
EMCNNKKH_01690 4.7e-43
EMCNNKKH_01691 6.8e-56 S TM2 domain
EMCNNKKH_01692 7.3e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
EMCNNKKH_01693 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EMCNNKKH_01694 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
EMCNNKKH_01695 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
EMCNNKKH_01696 1.2e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
EMCNNKKH_01697 6e-55 cof Q phosphatase activity
EMCNNKKH_01698 4e-34 cof Q phosphatase activity
EMCNNKKH_01699 2.8e-76 glcR K transcriptional regulator (DeoR family)
EMCNNKKH_01700 3.9e-21 glcR K transcriptional regulator (DeoR family)
EMCNNKKH_01701 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EMCNNKKH_01702 3.8e-40 K transcriptional
EMCNNKKH_01704 2.6e-76 S thiolester hydrolase activity
EMCNNKKH_01705 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
EMCNNKKH_01706 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EMCNNKKH_01707 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
EMCNNKKH_01708 1.9e-77 yhaI L Membrane
EMCNNKKH_01709 4.6e-260 pepC 3.4.22.40 E aminopeptidase
EMCNNKKH_01710 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
EMCNNKKH_01711 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
EMCNNKKH_01712 3.1e-95 ypsA S Belongs to the UPF0398 family
EMCNNKKH_01713 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
EMCNNKKH_01714 7.9e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
EMCNNKKH_01715 1e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
EMCNNKKH_01716 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
EMCNNKKH_01717 2.5e-23
EMCNNKKH_01718 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
EMCNNKKH_01719 3.1e-20 XK27_09675 K -acetyltransferase
EMCNNKKH_01720 9.3e-46 XK27_09675 K -acetyltransferase
EMCNNKKH_01721 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EMCNNKKH_01722 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EMCNNKKH_01723 5.3e-89 L Integrase core domain protein
EMCNNKKH_01724 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
EMCNNKKH_01725 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
EMCNNKKH_01726 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EMCNNKKH_01727 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
EMCNNKKH_01728 1.5e-97 ybhL S Belongs to the BI1 family
EMCNNKKH_01731 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EMCNNKKH_01732 9.6e-92 K transcriptional regulator
EMCNNKKH_01733 7.6e-36 yneF S UPF0154 protein
EMCNNKKH_01734 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EMCNNKKH_01735 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EMCNNKKH_01736 3.5e-99 XK27_09740 S Phosphoesterase
EMCNNKKH_01737 5.4e-86 ykuL S CBS domain
EMCNNKKH_01738 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
EMCNNKKH_01739 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EMCNNKKH_01740 2.3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EMCNNKKH_01741 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EMCNNKKH_01742 8.6e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
EMCNNKKH_01743 1.2e-258 trkH P Cation transport protein
EMCNNKKH_01744 1.8e-248 trkA P Potassium transporter peripheral membrane component
EMCNNKKH_01745 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EMCNNKKH_01746 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EMCNNKKH_01747 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
EMCNNKKH_01748 2.5e-161 K sequence-specific DNA binding
EMCNNKKH_01749 1.6e-32 V protein secretion by the type I secretion system
EMCNNKKH_01750 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EMCNNKKH_01751 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EMCNNKKH_01752 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
EMCNNKKH_01753 3.7e-22 yhaI L Membrane
EMCNNKKH_01754 1.4e-54 S Domain of unknown function (DUF4173)
EMCNNKKH_01755 6.8e-95 ureI S AmiS/UreI family transporter
EMCNNKKH_01756 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
EMCNNKKH_01757 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
EMCNNKKH_01758 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
EMCNNKKH_01759 6.6e-78 ureE O enzyme active site formation
EMCNNKKH_01760 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EMCNNKKH_01761 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EMCNNKKH_01762 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
EMCNNKKH_01763 2.7e-177 cbiM P PDGLE domain
EMCNNKKH_01764 1.7e-137 P cobalt transport protein
EMCNNKKH_01765 1.6e-131 cbiO P ABC transporter
EMCNNKKH_01766 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EMCNNKKH_01767 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EMCNNKKH_01768 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
EMCNNKKH_01769 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
EMCNNKKH_01770 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
EMCNNKKH_01771 2.3e-27
EMCNNKKH_01772 7.6e-146 S ABC-2 family transporter protein
EMCNNKKH_01773 4.1e-150 S transport system, permease component
EMCNNKKH_01774 1.8e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
EMCNNKKH_01775 4.2e-195 desK 2.7.13.3 T Histidine kinase
EMCNNKKH_01776 7.4e-135 yvfS V ABC-2 type transporter
EMCNNKKH_01777 2.1e-160 XK27_09825 V 'abc transporter, ATP-binding protein
EMCNNKKH_01781 2.3e-213 EGP Major facilitator Superfamily
EMCNNKKH_01782 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
EMCNNKKH_01783 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
EMCNNKKH_01784 3.9e-41 3.6.1.55 F NUDIX domain
EMCNNKKH_01786 3.7e-122 S An automated process has identified a potential problem with this gene model
EMCNNKKH_01787 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
EMCNNKKH_01788 1.6e-14 liaI KT membrane
EMCNNKKH_01789 2.6e-30 liaI KT membrane
EMCNNKKH_01790 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
EMCNNKKH_01791 0.0 V ABC transporter (permease)
EMCNNKKH_01792 5.8e-135 macB2 V ABC transporter, ATP-binding protein
EMCNNKKH_01793 6.2e-166 T Histidine kinase
EMCNNKKH_01794 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
EMCNNKKH_01795 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EMCNNKKH_01797 3.3e-69 pbuX F xanthine permease
EMCNNKKH_01798 9.2e-119 pbuX F xanthine permease
EMCNNKKH_01799 5.3e-248 norM V Multidrug efflux pump
EMCNNKKH_01800 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EMCNNKKH_01801 7.8e-236 brnQ E Component of the transport system for branched-chain amino acids
EMCNNKKH_01802 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
EMCNNKKH_01803 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
EMCNNKKH_01804 9.6e-26 csbD K CsbD-like
EMCNNKKH_01805 1.5e-245 yfnA E amino acid
EMCNNKKH_01806 6.1e-111 XK27_02070 S nitroreductase
EMCNNKKH_01807 2.1e-154 1.13.11.2 S glyoxalase
EMCNNKKH_01808 3.3e-77 ywnA K Transcriptional regulator
EMCNNKKH_01809 6.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
EMCNNKKH_01810 2.4e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
EMCNNKKH_01811 1.3e-111 drgA C Nitroreductase
EMCNNKKH_01812 2.4e-75 yoaK S Protein of unknown function (DUF1275)
EMCNNKKH_01813 3.1e-161 yvgN C reductase
EMCNNKKH_01814 5.6e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EMCNNKKH_01815 2.4e-09
EMCNNKKH_01816 1.6e-140 S Abortive infection C-terminus
EMCNNKKH_01817 0.0 L DEAD-like helicases superfamily
EMCNNKKH_01818 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
EMCNNKKH_01819 2.7e-285 XK27_07020 S Belongs to the UPF0371 family
EMCNNKKH_01821 1.1e-37 BP1961 P nitric oxide dioxygenase activity
EMCNNKKH_01822 1.6e-53 K response regulator
EMCNNKKH_01823 9.3e-72 S Signal peptide protein, YSIRK family
EMCNNKKH_01824 4.5e-61
EMCNNKKH_01825 5.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EMCNNKKH_01826 1.9e-35
EMCNNKKH_01827 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
EMCNNKKH_01828 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
EMCNNKKH_01829 5.8e-109 MA20_06410 E LysE type translocator
EMCNNKKH_01830 5.6e-08
EMCNNKKH_01831 2.7e-09
EMCNNKKH_01832 0.0 M family 8
EMCNNKKH_01833 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EMCNNKKH_01834 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EMCNNKKH_01835 5.2e-142 cmpC S abc transporter atp-binding protein
EMCNNKKH_01836 0.0 WQ51_06230 S ABC transporter substrate binding protein
EMCNNKKH_01837 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EMCNNKKH_01838 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
EMCNNKKH_01839 1.3e-145 cdsA 2.7.7.41 S Belongs to the CDS family
EMCNNKKH_01840 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EMCNNKKH_01841 9.8e-50 yajC U protein transport
EMCNNKKH_01842 1.9e-127 yeeN K transcriptional regulatory protein
EMCNNKKH_01843 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
EMCNNKKH_01844 1e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
EMCNNKKH_01845 1.7e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
EMCNNKKH_01846 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
EMCNNKKH_01847 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
EMCNNKKH_01848 4.8e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
EMCNNKKH_01849 5.4e-131 adcB P ABC transporter (Permease
EMCNNKKH_01850 2.2e-136 adcC P ABC transporter, ATP-binding protein
EMCNNKKH_01851 3.1e-72 adcR K transcriptional
EMCNNKKH_01852 1.9e-209 EGP Major facilitator Superfamily
EMCNNKKH_01853 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EMCNNKKH_01854 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EMCNNKKH_01857 9e-170 oppF P Belongs to the ABC transporter superfamily
EMCNNKKH_01858 1.3e-44 oppD P Belongs to the ABC transporter superfamily
EMCNNKKH_01859 4.8e-67 oppD P Belongs to the ABC transporter superfamily
EMCNNKKH_01860 2.5e-32 oppD P Belongs to the ABC transporter superfamily
EMCNNKKH_01861 8e-28 oppD P Belongs to the ABC transporter superfamily
EMCNNKKH_01862 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EMCNNKKH_01863 5.4e-46 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EMCNNKKH_01864 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
EMCNNKKH_01865 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
EMCNNKKH_01866 5.4e-99 oppA E ABC transporter substrate-binding protein
EMCNNKKH_01867 2.4e-19 oppA E ABC transporter substrate-binding protein
EMCNNKKH_01868 3.5e-274 sufB O assembly protein SufB
EMCNNKKH_01869 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
EMCNNKKH_01870 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EMCNNKKH_01871 6.3e-235 sufD O assembly protein SufD
EMCNNKKH_01872 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
EMCNNKKH_01873 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
EMCNNKKH_01874 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
EMCNNKKH_01875 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EMCNNKKH_01876 1.8e-276 glnP P ABC transporter
EMCNNKKH_01877 1e-123 glnQ E abc transporter atp-binding protein
EMCNNKKH_01880 5e-94 V VanZ like family
EMCNNKKH_01881 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EMCNNKKH_01882 6.5e-202 yhjX P Major Facilitator
EMCNNKKH_01883 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
EMCNNKKH_01884 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EMCNNKKH_01885 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EMCNNKKH_01886 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EMCNNKKH_01887 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EMCNNKKH_01888 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EMCNNKKH_01889 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
EMCNNKKH_01890 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EMCNNKKH_01891 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EMCNNKKH_01892 2.4e-83 nrdI F Belongs to the NrdI family
EMCNNKKH_01893 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
EMCNNKKH_01894 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EMCNNKKH_01895 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
EMCNNKKH_01896 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
EMCNNKKH_01897 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
EMCNNKKH_01898 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EMCNNKKH_01899 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
EMCNNKKH_01900 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EMCNNKKH_01901 3e-148 ykuT M mechanosensitive ion channel
EMCNNKKH_01902 1.6e-77 sigH K DNA-templated transcription, initiation

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)