ORF_ID e_value Gene_name EC_number CAZy COGs Description
PACLEGCH_00001 3.4e-17
PACLEGCH_00002 8.5e-187 lplA 6.3.1.20 H Lipoate-protein ligase
PACLEGCH_00003 4.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PACLEGCH_00004 0.0 pepN 3.4.11.2 E aminopeptidase
PACLEGCH_00005 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
PACLEGCH_00006 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PACLEGCH_00007 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PACLEGCH_00008 1.2e-155 pstA P phosphate transport system permease
PACLEGCH_00009 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
PACLEGCH_00010 3.3e-158 pstS P phosphate
PACLEGCH_00011 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PACLEGCH_00012 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PACLEGCH_00013 1.9e-43 yktA S Belongs to the UPF0223 family
PACLEGCH_00014 1.1e-62 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PACLEGCH_00015 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PACLEGCH_00016 3.2e-150 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PACLEGCH_00017 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
PACLEGCH_00018 6.1e-84 XK27_04775 S hemerythrin HHE cation binding domain
PACLEGCH_00019 6.3e-32 M1-755 P Hemerythrin HHE cation binding domain protein
PACLEGCH_00020 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
PACLEGCH_00021 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PACLEGCH_00022 2.2e-134 S haloacid dehalogenase-like hydrolase
PACLEGCH_00023 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
PACLEGCH_00024 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PACLEGCH_00025 3.1e-240 agcS E (Alanine) symporter
PACLEGCH_00026 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PACLEGCH_00027 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
PACLEGCH_00029 2.3e-20 yecS P amino acid transport
PACLEGCH_00030 1.4e-62 yecS P ABC transporter (Permease
PACLEGCH_00031 1.6e-266 dtpT E transporter
PACLEGCH_00032 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PACLEGCH_00033 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PACLEGCH_00034 9.5e-32 csm6 S Psort location Cytoplasmic, score
PACLEGCH_00036 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
PACLEGCH_00037 2.3e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
PACLEGCH_00038 1.6e-117 csm3 L RAMP superfamily
PACLEGCH_00039 2.5e-62 csm2 L Csm2 Type III-A
PACLEGCH_00040 0.0 csm1 S CRISPR-associated protein Csm1 family
PACLEGCH_00041 6.8e-133 cas6 S CRISPR-associated endoribonuclease Cas6
PACLEGCH_00042 1.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PACLEGCH_00043 1.3e-187 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PACLEGCH_00044 7.2e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PACLEGCH_00045 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PACLEGCH_00046 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
PACLEGCH_00047 5.7e-118 S TraX protein
PACLEGCH_00049 3.5e-28 3.4.13.21 I Protein conserved in bacteria
PACLEGCH_00050 3.1e-89 FNV0100 F Belongs to the Nudix hydrolase family
PACLEGCH_00051 3.7e-190
PACLEGCH_00052 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PACLEGCH_00054 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
PACLEGCH_00055 1.8e-24 yclQ P ABC-type enterochelin transport system, periplasmic component
PACLEGCH_00056 4.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
PACLEGCH_00057 1.2e-143 2.4.2.3 F Phosphorylase superfamily
PACLEGCH_00060 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
PACLEGCH_00061 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
PACLEGCH_00062 6e-08 S Hydrolases of the alpha beta superfamily
PACLEGCH_00063 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
PACLEGCH_00064 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PACLEGCH_00065 1.8e-159 czcD P cation diffusion facilitator family transporter
PACLEGCH_00066 1.2e-97 K Transcriptional regulator, TetR family
PACLEGCH_00067 1.6e-10
PACLEGCH_00068 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PACLEGCH_00069 6.4e-104 V ABC transporter (Permease
PACLEGCH_00070 3.4e-92 amiA E ABC transporter, substrate-binding protein, family 5
PACLEGCH_00071 4.2e-278 amiC P ABC transporter (Permease
PACLEGCH_00072 4.9e-168 amiD P ABC transporter (Permease
PACLEGCH_00073 2.2e-204 oppD P Belongs to the ABC transporter superfamily
PACLEGCH_00074 4.3e-172 oppF P Belongs to the ABC transporter superfamily
PACLEGCH_00075 3.3e-133 V ATPase activity
PACLEGCH_00076 2.8e-120 skfE V abc transporter atp-binding protein
PACLEGCH_00077 8.6e-63 yvoA_1 K Transcriptional
PACLEGCH_00078 2.1e-148 supH S overlaps another CDS with the same product name
PACLEGCH_00079 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
PACLEGCH_00080 2.8e-212 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PACLEGCH_00081 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PACLEGCH_00082 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
PACLEGCH_00083 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PACLEGCH_00084 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PACLEGCH_00085 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PACLEGCH_00086 2e-132 stp 3.1.3.16 T phosphatase
PACLEGCH_00087 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PACLEGCH_00088 5.4e-119 yvqF KT membrane
PACLEGCH_00089 5.8e-175 vraS 2.7.13.3 T Histidine kinase
PACLEGCH_00090 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PACLEGCH_00093 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PACLEGCH_00094 2.1e-134 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PACLEGCH_00095 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PACLEGCH_00096 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PACLEGCH_00097 2.3e-87 L Transposase
PACLEGCH_00098 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
PACLEGCH_00099 4.3e-40 V abc transporter atp-binding protein
PACLEGCH_00100 1.7e-20 V abc transporter atp-binding protein
PACLEGCH_00101 3e-26 V abc transporter atp-binding protein
PACLEGCH_00102 1.1e-23 V abc transporter atp-binding protein
PACLEGCH_00103 1.4e-67 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
PACLEGCH_00104 7.5e-109 M translation initiation factor activity
PACLEGCH_00105 3.3e-74 M translation initiation factor activity
PACLEGCH_00106 1.2e-25 L transposition
PACLEGCH_00107 2.3e-184 galR K Transcriptional regulator
PACLEGCH_00108 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PACLEGCH_00109 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PACLEGCH_00110 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PACLEGCH_00111 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PACLEGCH_00112 0.0 lacS G transporter
PACLEGCH_00113 0.0 lacL 3.2.1.23 G -beta-galactosidase
PACLEGCH_00114 1.3e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PACLEGCH_00115 0.0 sbcC L ATPase involved in DNA repair
PACLEGCH_00116 2.8e-85
PACLEGCH_00118 1.8e-87 L transposase activity
PACLEGCH_00119 1.4e-150 L Integrase core domain protein
PACLEGCH_00120 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PACLEGCH_00122 5.5e-258 I radical SAM domain protein
PACLEGCH_00123 1.2e-176 EGP Major Facilitator Superfamily
PACLEGCH_00124 3.9e-110 C Fe-S oxidoreductases
PACLEGCH_00126 1.1e-151 V MatE
PACLEGCH_00128 5.9e-155 S AIPR protein
PACLEGCH_00129 8.9e-20 K Cro/C1-type HTH DNA-binding domain
PACLEGCH_00130 9.1e-160 haeIIIM 2.1.1.37 L C-5 cytosine-specific DNA methylase
PACLEGCH_00131 2e-57 L PFAM Restriction endonuclease, type II, HaeIII
PACLEGCH_00132 3.2e-19 pvuIIC K helix-turn-helix
PACLEGCH_00133 2.1e-14
PACLEGCH_00134 3.2e-28
PACLEGCH_00135 6.6e-38 L transposase activity
PACLEGCH_00136 4e-107 L COG2801 Transposase and inactivated derivatives
PACLEGCH_00137 0.0 T Nacht domain
PACLEGCH_00138 4.5e-39 sip L Belongs to the 'phage' integrase family
PACLEGCH_00139 2e-22
PACLEGCH_00140 4.7e-107 K Peptidase S24-like protein
PACLEGCH_00141 5.2e-124 E IrrE N-terminal-like domain
PACLEGCH_00142 3.3e-10
PACLEGCH_00144 1e-46 K Helix-turn-helix XRE-family like proteins
PACLEGCH_00145 8.6e-42
PACLEGCH_00146 6.6e-73
PACLEGCH_00147 2.4e-274 ydcQ D Ftsk spoiiie family protein
PACLEGCH_00148 4.6e-222 K Replication initiation factor
PACLEGCH_00149 4.3e-33
PACLEGCH_00150 3.5e-89
PACLEGCH_00151 4e-160 S Conjugative transposon protein TcpC
PACLEGCH_00152 1.2e-32
PACLEGCH_00153 1.9e-68 S TcpE family
PACLEGCH_00154 0.0 yddE S AAA-like domain
PACLEGCH_00155 2.1e-266
PACLEGCH_00156 4.4e-30
PACLEGCH_00157 2.5e-166 isp2 S pathogenesis
PACLEGCH_00158 4e-16
PACLEGCH_00159 2e-199 L DNA integration
PACLEGCH_00160 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
PACLEGCH_00162 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
PACLEGCH_00163 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
PACLEGCH_00164 2.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
PACLEGCH_00165 1.9e-33 L PFAM Integrase, catalytic core
PACLEGCH_00166 2.1e-115 L PFAM Integrase, catalytic core
PACLEGCH_00167 3.3e-62 rplQ J ribosomal protein l17
PACLEGCH_00168 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PACLEGCH_00169 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PACLEGCH_00170 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PACLEGCH_00171 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PACLEGCH_00172 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PACLEGCH_00173 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PACLEGCH_00174 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PACLEGCH_00175 4.4e-58 rplO J binds to the 23S rRNA
PACLEGCH_00176 2.5e-23 rpmD J ribosomal protein l30
PACLEGCH_00177 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PACLEGCH_00178 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PACLEGCH_00179 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PACLEGCH_00180 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PACLEGCH_00181 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PACLEGCH_00182 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PACLEGCH_00183 4.1e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PACLEGCH_00184 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PACLEGCH_00185 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PACLEGCH_00186 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
PACLEGCH_00187 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PACLEGCH_00188 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PACLEGCH_00189 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PACLEGCH_00190 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PACLEGCH_00191 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PACLEGCH_00192 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PACLEGCH_00193 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
PACLEGCH_00194 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PACLEGCH_00195 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PACLEGCH_00196 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PACLEGCH_00197 0.0 XK27_09800 I Acyltransferase
PACLEGCH_00198 1.7e-35 XK27_09805 S MORN repeat protein
PACLEGCH_00199 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PACLEGCH_00200 2.1e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PACLEGCH_00201 8.8e-83 adk 2.7.4.3 F topology modulation protein
PACLEGCH_00202 3.1e-172 yxaM EGP Major facilitator Superfamily
PACLEGCH_00203 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
PACLEGCH_00204 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PACLEGCH_00205 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PACLEGCH_00206 6.6e-61 EGP Major facilitator Superfamily
PACLEGCH_00207 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
PACLEGCH_00208 1.3e-212 pqqE C radical SAM domain protein
PACLEGCH_00211 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PACLEGCH_00212 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PACLEGCH_00213 3.9e-19 IQ Acetoin reductase
PACLEGCH_00214 1.8e-51 IQ Acetoin reductase
PACLEGCH_00215 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PACLEGCH_00216 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PACLEGCH_00217 1.1e-152 XK27_05470 E Methionine synthase
PACLEGCH_00218 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PACLEGCH_00219 1.8e-251 T PhoQ Sensor
PACLEGCH_00220 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PACLEGCH_00221 6.7e-153 S TraX protein
PACLEGCH_00222 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PACLEGCH_00223 8.3e-159 dprA LU DNA protecting protein DprA
PACLEGCH_00224 8.2e-168 GK ROK family
PACLEGCH_00225 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PACLEGCH_00226 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PACLEGCH_00227 1.8e-127 K DNA-binding helix-turn-helix protein
PACLEGCH_00228 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
PACLEGCH_00229 4.1e-87 niaX
PACLEGCH_00230 3.2e-265 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PACLEGCH_00231 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PACLEGCH_00232 2.9e-125 gntR1 K transcriptional
PACLEGCH_00233 1.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PACLEGCH_00234 3.6e-49 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
PACLEGCH_00235 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
PACLEGCH_00236 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
PACLEGCH_00237 4.2e-139 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PACLEGCH_00238 3.5e-40 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PACLEGCH_00239 1.2e-157 aatB ET ABC transporter substrate-binding protein
PACLEGCH_00240 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
PACLEGCH_00241 4e-105 artQ P ABC transporter (Permease
PACLEGCH_00242 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
PACLEGCH_00243 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PACLEGCH_00244 2.6e-166 cpsY K Transcriptional regulator
PACLEGCH_00245 1.9e-83 L transposition
PACLEGCH_00246 2.9e-115 mur1 NU muramidase
PACLEGCH_00247 2.7e-172 yeiH S Membrane
PACLEGCH_00249 1.7e-08
PACLEGCH_00250 3.1e-292 adcA P Belongs to the bacterial solute-binding protein 9 family
PACLEGCH_00251 1.3e-88 XK27_10720 D peptidase activity
PACLEGCH_00252 3.4e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
PACLEGCH_00253 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
PACLEGCH_00254 1.2e-155 glcU U Glucose uptake
PACLEGCH_00255 3.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
PACLEGCH_00256 1.5e-55 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
PACLEGCH_00258 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
PACLEGCH_00259 4.6e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
PACLEGCH_00261 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
PACLEGCH_00262 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PACLEGCH_00263 4.2e-83 S Putative small multi-drug export protein
PACLEGCH_00264 6.2e-76 ctsR K Belongs to the CtsR family
PACLEGCH_00265 0.0 clpC O Belongs to the ClpA ClpB family
PACLEGCH_00266 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PACLEGCH_00267 1.6e-59 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PACLEGCH_00268 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PACLEGCH_00269 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PACLEGCH_00270 6.9e-144 S SseB protein N-terminal domain
PACLEGCH_00271 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
PACLEGCH_00272 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PACLEGCH_00273 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PACLEGCH_00276 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PACLEGCH_00277 3.5e-91 yacP S RNA-binding protein containing a PIN domain
PACLEGCH_00278 3.4e-155 degV S DegV family
PACLEGCH_00279 1.8e-31 K helix-turn-helix
PACLEGCH_00280 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PACLEGCH_00281 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PACLEGCH_00282 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PACLEGCH_00283 1.1e-184 L Phage integrase family
PACLEGCH_00284 2.2e-22
PACLEGCH_00285 2.3e-154
PACLEGCH_00287 3.3e-106 D ftsk spoiiie
PACLEGCH_00288 2.2e-19 D FtsK/SpoIIIE family
PACLEGCH_00291 3.6e-218 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
PACLEGCH_00292 0.0 res_1 3.1.21.5 S DEAD-like helicases superfamily
PACLEGCH_00293 8.2e-224 int L Belongs to the 'phage' integrase family
PACLEGCH_00294 1.8e-38 S Helix-turn-helix domain
PACLEGCH_00295 4.9e-173
PACLEGCH_00297 6.3e-74 isp2 S pathogenesis
PACLEGCH_00298 5.7e-91 tnp L Transposase
PACLEGCH_00299 3.3e-225 capA M Bacterial capsule synthesis protein
PACLEGCH_00300 3.6e-39 gcvR T UPF0237 protein
PACLEGCH_00301 1.9e-242 XK27_08635 S UPF0210 protein
PACLEGCH_00302 2.2e-38 ais G alpha-ribazole phosphatase activity
PACLEGCH_00303 1.6e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PACLEGCH_00304 1.3e-102 acmA 3.2.1.17 NU amidase activity
PACLEGCH_00305 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PACLEGCH_00306 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PACLEGCH_00307 9.8e-298 dnaK O Heat shock 70 kDa protein
PACLEGCH_00308 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PACLEGCH_00309 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PACLEGCH_00310 6.2e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
PACLEGCH_00311 1.7e-60 hmpT S membrane
PACLEGCH_00313 2.4e-101 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PACLEGCH_00314 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PACLEGCH_00315 1.4e-302 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
PACLEGCH_00316 1.3e-48 malR K Transcriptional regulator
PACLEGCH_00317 2.3e-23 L Transposase
PACLEGCH_00318 4.6e-25 tatA U protein secretion
PACLEGCH_00319 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PACLEGCH_00320 7.4e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
PACLEGCH_00321 3.3e-233 ycdB P peroxidase
PACLEGCH_00322 7.1e-153 ycdO P periplasmic lipoprotein involved in iron transport
PACLEGCH_00323 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PACLEGCH_00324 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PACLEGCH_00325 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PACLEGCH_00326 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PACLEGCH_00327 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PACLEGCH_00328 1.9e-37 3.5.1.28 NU amidase activity
PACLEGCH_00329 8.5e-266 3.5.1.28 NU amidase activity
PACLEGCH_00330 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PACLEGCH_00331 3.8e-11 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PACLEGCH_00332 0.0 lpdA 1.8.1.4 C Dehydrogenase
PACLEGCH_00333 1.8e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PACLEGCH_00334 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PACLEGCH_00335 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PACLEGCH_00336 3.6e-46 hpk9 2.7.13.3 T protein histidine kinase activity
PACLEGCH_00337 3.5e-241 cas3 L CRISPR-associated helicase, Cas3
PACLEGCH_00338 0.0 S the current gene model (or a revised gene model) may contain a frame shift
PACLEGCH_00339 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PACLEGCH_00340 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PACLEGCH_00341 1.6e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PACLEGCH_00342 5.9e-22 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PACLEGCH_00343 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
PACLEGCH_00344 2.3e-26 3.4.16.4 M Belongs to the peptidase S11 family
PACLEGCH_00345 4.3e-83 3.4.16.4 M Belongs to the peptidase S11 family
PACLEGCH_00346 1.2e-157 rssA S Phospholipase, patatin family
PACLEGCH_00347 1.8e-69 estA E GDSL-like protein
PACLEGCH_00348 3.4e-29 estA E Lysophospholipase L1 and related esterases
PACLEGCH_00349 5.9e-291 S unusual protein kinase
PACLEGCH_00350 4.9e-39 S granule-associated protein
PACLEGCH_00351 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PACLEGCH_00352 7e-116 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PACLEGCH_00353 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PACLEGCH_00354 2.5e-198 S hmm pf01594
PACLEGCH_00355 5.1e-102 G Belongs to the phosphoglycerate mutase family
PACLEGCH_00356 1.5e-33 G Belongs to the phosphoglycerate mutase family
PACLEGCH_00357 9.2e-93 V VanZ like family
PACLEGCH_00358 3.2e-51 tnp L DDE domain
PACLEGCH_00359 1.8e-24 S Bacterial transferase hexapeptide (six repeats)
PACLEGCH_00360 1.7e-156 L EVIDENCE EXPERIMENTAL PMID 1328163 BIO14.04 Transposon related functions. BELONGS TO THE IS3 IS150 IS904 FAMILY OF TRANSPOSASE. There are 7 such elements in the chromosome
PACLEGCH_00361 3.7e-58 L Helix-turn-helix domain
PACLEGCH_00362 3e-190 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
PACLEGCH_00363 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PACLEGCH_00364 3.5e-91 dps P Belongs to the Dps family
PACLEGCH_00365 1.1e-80 perR P Belongs to the Fur family
PACLEGCH_00366 8.4e-28 yqgQ S protein conserved in bacteria
PACLEGCH_00367 2.2e-179 glk 2.7.1.2 G Glucokinase
PACLEGCH_00368 0.0 typA T GTP-binding protein TypA
PACLEGCH_00370 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PACLEGCH_00371 1.3e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PACLEGCH_00372 3.1e-169 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PACLEGCH_00373 1.5e-250 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PACLEGCH_00374 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PACLEGCH_00375 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PACLEGCH_00376 6.8e-96 sepF D cell septum assembly
PACLEGCH_00377 2.6e-34 yggT D integral membrane protein
PACLEGCH_00378 6.1e-143 ylmH T S4 RNA-binding domain
PACLEGCH_00379 1.8e-135 divIVA D Cell division protein DivIVA
PACLEGCH_00380 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PACLEGCH_00381 8.4e-10
PACLEGCH_00382 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
PACLEGCH_00383 2e-45 rpmE2 J 50S ribosomal protein L31
PACLEGCH_00384 1.5e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PACLEGCH_00385 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
PACLEGCH_00386 8.9e-155 gst O Glutathione S-transferase
PACLEGCH_00387 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PACLEGCH_00388 2.4e-112 tdk 2.7.1.21 F thymidine kinase
PACLEGCH_00389 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PACLEGCH_00390 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PACLEGCH_00391 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PACLEGCH_00392 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PACLEGCH_00393 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
PACLEGCH_00394 8e-100 pvaA M lytic transglycosylase activity
PACLEGCH_00395 0.0 yfiB1 V abc transporter atp-binding protein
PACLEGCH_00396 0.0 XK27_10035 V abc transporter atp-binding protein
PACLEGCH_00397 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
PACLEGCH_00398 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PACLEGCH_00399 3.9e-237 dltB M Membrane protein involved in D-alanine export
PACLEGCH_00400 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PACLEGCH_00401 1.4e-229 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PACLEGCH_00402 1e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PACLEGCH_00403 1.7e-122 comFC S Competence protein
PACLEGCH_00404 5.3e-253 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PACLEGCH_00405 6.3e-111 yvyE 3.4.13.9 S YigZ family
PACLEGCH_00406 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PACLEGCH_00407 3.3e-43 acuB S IMP dehydrogenase activity
PACLEGCH_00408 2.8e-70 acuB S IMP dehydrogenase activity
PACLEGCH_00409 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PACLEGCH_00410 5.1e-84 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PACLEGCH_00411 1.8e-23 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PACLEGCH_00412 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
PACLEGCH_00413 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
PACLEGCH_00414 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PACLEGCH_00415 7.1e-46 ylbG S UPF0298 protein
PACLEGCH_00416 3.4e-74 ylbF S Belongs to the UPF0342 family
PACLEGCH_00417 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PACLEGCH_00418 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PACLEGCH_00420 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PACLEGCH_00421 1.8e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
PACLEGCH_00422 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
PACLEGCH_00423 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
PACLEGCH_00424 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PACLEGCH_00425 6e-157 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PACLEGCH_00426 3.6e-48 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PACLEGCH_00427 1.8e-45 yvdD 3.2.2.10 S Belongs to the LOG family
PACLEGCH_00428 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PACLEGCH_00429 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PACLEGCH_00430 1.4e-41 ylxQ J ribosomal protein
PACLEGCH_00431 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
PACLEGCH_00432 3.1e-212 nusA K Participates in both transcription termination and antitermination
PACLEGCH_00433 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
PACLEGCH_00434 1.2e-219 brpA K Transcriptional
PACLEGCH_00435 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
PACLEGCH_00436 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
PACLEGCH_00437 1.9e-248 pbuO S permease
PACLEGCH_00438 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PACLEGCH_00439 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
PACLEGCH_00440 1.3e-174 manL 2.7.1.191 G pts system
PACLEGCH_00441 1.6e-117 manM G pts system
PACLEGCH_00442 1.9e-169 manN G PTS system mannose fructose sorbose family IID component
PACLEGCH_00443 6.5e-63 manO S protein conserved in bacteria
PACLEGCH_00444 2.8e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PACLEGCH_00445 1.3e-29 rpsT J rRNA binding
PACLEGCH_00446 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
PACLEGCH_00447 4.4e-106 rsmC 2.1.1.172 J Methyltransferase small domain protein
PACLEGCH_00448 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PACLEGCH_00449 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PACLEGCH_00450 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PACLEGCH_00451 1.4e-38 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PACLEGCH_00452 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PACLEGCH_00453 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
PACLEGCH_00454 3.2e-281 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PACLEGCH_00455 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
PACLEGCH_00456 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
PACLEGCH_00457 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PACLEGCH_00458 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PACLEGCH_00459 3.1e-81 ypmB S Protein conserved in bacteria
PACLEGCH_00460 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PACLEGCH_00461 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PACLEGCH_00462 1.5e-07
PACLEGCH_00463 3e-13
PACLEGCH_00464 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
PACLEGCH_00465 9.8e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PACLEGCH_00466 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
PACLEGCH_00467 2.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PACLEGCH_00468 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PACLEGCH_00469 4.2e-18 D nuclear chromosome segregation
PACLEGCH_00470 5.3e-136 yejC S cyclic nucleotide-binding protein
PACLEGCH_00471 1.2e-163 rapZ S Displays ATPase and GTPase activities
PACLEGCH_00472 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PACLEGCH_00473 8.7e-162 whiA K May be required for sporulation
PACLEGCH_00474 8.2e-120 pepD E Dipeptidase
PACLEGCH_00475 5.8e-41 pepD E dipeptidase activity
PACLEGCH_00476 5.4e-32 cspD K Cold shock protein domain
PACLEGCH_00477 3.6e-42 K Cold-Shock Protein
PACLEGCH_00478 5e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
PACLEGCH_00479 1.9e-138 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
PACLEGCH_00480 1.6e-24 U response to pH
PACLEGCH_00481 0.0 yfmR S abc transporter atp-binding protein
PACLEGCH_00482 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PACLEGCH_00483 5.1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PACLEGCH_00484 5.5e-75 XK27_08360 S EDD domain protein, DegV family
PACLEGCH_00485 6.4e-61 XK27_08360 S EDD domain protein, DegV family
PACLEGCH_00486 2.6e-64 WQ51_03320 S cog cog4835
PACLEGCH_00487 1.4e-130 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PACLEGCH_00488 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PACLEGCH_00489 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PACLEGCH_00490 6.4e-29 2.3.1.128 K acetyltransferase
PACLEGCH_00491 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PACLEGCH_00492 1.1e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PACLEGCH_00493 6.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PACLEGCH_00494 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PACLEGCH_00496 4.5e-241 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PACLEGCH_00497 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PACLEGCH_00498 0.0 fruA 2.7.1.202 G phosphotransferase system
PACLEGCH_00499 3.8e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PACLEGCH_00500 2.1e-113 fruR K transcriptional
PACLEGCH_00501 1.8e-84 L Transposase
PACLEGCH_00502 7.8e-206 rny D Endoribonuclease that initiates mRNA decay
PACLEGCH_00503 3.2e-42 L Transposase
PACLEGCH_00504 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PACLEGCH_00505 1.1e-12
PACLEGCH_00506 1.3e-87 S Fusaric acid resistance protein-like
PACLEGCH_00507 8.5e-63 glnR K Transcriptional regulator
PACLEGCH_00508 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
PACLEGCH_00509 2.7e-40 pscB M CHAP domain protein
PACLEGCH_00510 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PACLEGCH_00511 2.5e-33 ykzG S Belongs to the UPF0356 family
PACLEGCH_00512 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
PACLEGCH_00513 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PACLEGCH_00514 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PACLEGCH_00515 2.5e-116 azlC E AzlC protein
PACLEGCH_00516 2e-47 azlD E branched-chain amino acid
PACLEGCH_00517 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PACLEGCH_00518 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PACLEGCH_00519 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PACLEGCH_00520 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PACLEGCH_00521 1e-93 cvpA S toxin biosynthetic process
PACLEGCH_00522 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PACLEGCH_00523 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PACLEGCH_00528 9.5e-230 mutY L A G-specific adenine glycosylase
PACLEGCH_00529 3.6e-41 XK27_05745
PACLEGCH_00530 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PACLEGCH_00531 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PACLEGCH_00532 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PACLEGCH_00534 3.1e-124 XK27_01040 S Pfam PF06570
PACLEGCH_00535 2e-169 corA P COG0598 Mg2 and Co2 transporters
PACLEGCH_00536 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PACLEGCH_00539 1e-58 V 'abc transporter, ATP-binding protein
PACLEGCH_00540 8e-44 V 'abc transporter, ATP-binding protein
PACLEGCH_00542 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
PACLEGCH_00543 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
PACLEGCH_00544 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PACLEGCH_00545 3.4e-62 yqhY S protein conserved in bacteria
PACLEGCH_00546 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PACLEGCH_00547 7.5e-180 scrR K Transcriptional
PACLEGCH_00548 5.4e-291 scrB 3.2.1.26 GH32 G invertase
PACLEGCH_00549 0.0 scrA 2.7.1.211 G pts system
PACLEGCH_00550 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
PACLEGCH_00551 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
PACLEGCH_00553 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PACLEGCH_00554 2.9e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PACLEGCH_00555 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PACLEGCH_00556 4.5e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PACLEGCH_00557 6.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PACLEGCH_00558 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PACLEGCH_00559 1.4e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PACLEGCH_00560 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
PACLEGCH_00561 2.9e-18 yebC M Membrane
PACLEGCH_00562 2e-80 yebC M Membrane
PACLEGCH_00563 3.6e-66 KT response to antibiotic
PACLEGCH_00564 5.2e-75 XK27_02470 K LytTr DNA-binding domain
PACLEGCH_00565 2.6e-121 liaI S membrane
PACLEGCH_00566 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PACLEGCH_00567 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PACLEGCH_00568 5.2e-125 S Protein of unknown function (DUF554)
PACLEGCH_00569 8.1e-134 ecsA_2 V abc transporter atp-binding protein
PACLEGCH_00570 2.2e-285 XK27_00765
PACLEGCH_00571 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PACLEGCH_00572 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PACLEGCH_00573 1.3e-08 D nuclear chromosome segregation
PACLEGCH_00574 9.7e-32 yhaI J Protein of unknown function (DUF805)
PACLEGCH_00575 3e-128
PACLEGCH_00576 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PACLEGCH_00577 4.3e-47 ftsL D cell division protein FtsL
PACLEGCH_00578 0.0 ftsI 3.4.16.4 M penicillin-binding protein
PACLEGCH_00579 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PACLEGCH_00580 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PACLEGCH_00582 5.1e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PACLEGCH_00583 3.6e-70 yutD J protein conserved in bacteria
PACLEGCH_00584 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PACLEGCH_00585 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
PACLEGCH_00587 0.0 mdlA V abc transporter atp-binding protein
PACLEGCH_00588 0.0 mdlB V abc transporter atp-binding protein
PACLEGCH_00589 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PACLEGCH_00590 7.3e-237 mesE M Transport protein ComB
PACLEGCH_00592 9.9e-239 blpH 2.7.13.3 T protein histidine kinase activity
PACLEGCH_00593 7.4e-135 agrA KT phosphorelay signal transduction system
PACLEGCH_00596 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
PACLEGCH_00603 6.7e-98 blpT
PACLEGCH_00604 2.9e-28 blpT
PACLEGCH_00605 3e-47 spiA K sequence-specific DNA binding
PACLEGCH_00608 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PACLEGCH_00609 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PACLEGCH_00610 5e-44 V CAAX protease self-immunity
PACLEGCH_00611 4.6e-140 cppA E CppA N-terminal
PACLEGCH_00612 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
PACLEGCH_00613 1.2e-117 ybbL S abc transporter atp-binding protein
PACLEGCH_00614 1.5e-127 ybbM S transport system, permease component
PACLEGCH_00615 2.9e-87 D nuclear chromosome segregation
PACLEGCH_00616 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
PACLEGCH_00617 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PACLEGCH_00618 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
PACLEGCH_00619 0.0 pflB 2.3.1.54 C formate acetyltransferase'
PACLEGCH_00620 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PACLEGCH_00622 5.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PACLEGCH_00623 1e-162 yxeN P ABC transporter (Permease
PACLEGCH_00624 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
PACLEGCH_00625 1.9e-09 S Protein of unknown function (DUF4059)
PACLEGCH_00626 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PACLEGCH_00627 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
PACLEGCH_00628 5.9e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PACLEGCH_00629 2.2e-196 ylbL T Belongs to the peptidase S16 family
PACLEGCH_00630 1.3e-184 yhcC S radical SAM protein
PACLEGCH_00631 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
PACLEGCH_00633 0.0 yjcE P NhaP-type Na H and K H antiporters
PACLEGCH_00634 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
PACLEGCH_00635 7.1e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
PACLEGCH_00636 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PACLEGCH_00639 2.4e-75 XK27_03180 T universal stress protein
PACLEGCH_00640 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
PACLEGCH_00641 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PACLEGCH_00642 6.8e-101 pncA Q isochorismatase
PACLEGCH_00643 4.8e-154 hlpA M Belongs to the NlpA lipoprotein family
PACLEGCH_00644 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PACLEGCH_00645 1.5e-258 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PACLEGCH_00646 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PACLEGCH_00647 1.7e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PACLEGCH_00648 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PACLEGCH_00649 1.3e-57
PACLEGCH_00650 1.3e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PACLEGCH_00651 1.8e-98 yqeG S hydrolase of the HAD superfamily
PACLEGCH_00652 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PACLEGCH_00653 3.5e-49 yhbY J RNA-binding protein
PACLEGCH_00654 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PACLEGCH_00655 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PACLEGCH_00656 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PACLEGCH_00657 2e-140 yqeM Q Methyltransferase domain protein
PACLEGCH_00658 6.9e-206 ylbM S Belongs to the UPF0348 family
PACLEGCH_00659 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
PACLEGCH_00660 5.2e-105
PACLEGCH_00661 2.7e-57 S CD20-like family
PACLEGCH_00662 2.3e-10
PACLEGCH_00663 1.9e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PACLEGCH_00664 1.2e-132 ecsA V abc transporter atp-binding protein
PACLEGCH_00665 4.3e-181 ecsB U ABC transporter
PACLEGCH_00666 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
PACLEGCH_00667 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PACLEGCH_00669 7.7e-227 ytfP S Flavoprotein
PACLEGCH_00670 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PACLEGCH_00671 1.6e-63 XK27_02560 S cog cog2151
PACLEGCH_00672 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
PACLEGCH_00673 1.4e-104 dnaQ 2.7.7.7 L DNA polymerase III
PACLEGCH_00674 1e-128 K transcriptional regulator, MerR family
PACLEGCH_00675 5.1e-47 L transposase activity
PACLEGCH_00676 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PACLEGCH_00677 6.2e-28
PACLEGCH_00678 0.0 ctpE P E1-E2 ATPase
PACLEGCH_00679 1.4e-54
PACLEGCH_00680 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
PACLEGCH_00681 5.9e-255 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PACLEGCH_00682 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
PACLEGCH_00683 1.3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PACLEGCH_00684 2.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PACLEGCH_00685 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
PACLEGCH_00686 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PACLEGCH_00687 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PACLEGCH_00688 2.7e-73 copY K Copper transport repressor, CopY TcrY family
PACLEGCH_00689 0.0 copA 3.6.3.54 P P-type ATPase
PACLEGCH_00690 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
PACLEGCH_00691 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PACLEGCH_00692 6e-115 papP P ABC transporter (Permease
PACLEGCH_00693 3e-106 P ABC transporter (Permease
PACLEGCH_00694 7.6e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
PACLEGCH_00695 1.1e-155 cjaA ET ABC transporter substrate-binding protein
PACLEGCH_00699 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PACLEGCH_00700 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
PACLEGCH_00701 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PACLEGCH_00702 2.7e-200 yjbB G Permeases of the major facilitator superfamily
PACLEGCH_00703 2.1e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PACLEGCH_00704 7.8e-100 thiT S Thiamine transporter
PACLEGCH_00705 2.5e-62 yjqA S Bacterial PH domain
PACLEGCH_00706 5e-104 corA P CorA-like protein
PACLEGCH_00707 1.3e-237 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PACLEGCH_00708 1e-41 yazA L endonuclease containing a URI domain
PACLEGCH_00709 2.7e-140 yabB 2.1.1.223 L Methyltransferase
PACLEGCH_00710 5.9e-48 nodB3 G polysaccharide deacetylase
PACLEGCH_00711 5.4e-79 nodB3 G polysaccharide deacetylase
PACLEGCH_00712 1.9e-141 plsC 2.3.1.51 I Acyltransferase
PACLEGCH_00713 1.1e-23
PACLEGCH_00714 2.8e-97
PACLEGCH_00715 2e-55 S ABC-2 type transporter
PACLEGCH_00716 9.2e-156 V AAA domain, putative AbiEii toxin, Type IV TA system
PACLEGCH_00718 2.5e-139 C Iron-sulfur cluster-binding domain
PACLEGCH_00719 2.7e-112 C 4Fe-4S single cluster domain
PACLEGCH_00721 1.1e-140 Z012_04635 K Helix-turn-helix XRE-family like proteins
PACLEGCH_00722 7.5e-97 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PACLEGCH_00723 0.0 comEC S Competence protein ComEC
PACLEGCH_00724 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PACLEGCH_00725 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
PACLEGCH_00726 3.3e-231 ytoI K transcriptional regulator containing CBS domains
PACLEGCH_00727 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PACLEGCH_00728 7.4e-164 rbn E Belongs to the UPF0761 family
PACLEGCH_00729 3.7e-85 ccl S cog cog4708
PACLEGCH_00730 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PACLEGCH_00731 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PACLEGCH_00732 1.9e-55 L Transposase
PACLEGCH_00733 2.1e-74 S QueT transporter
PACLEGCH_00734 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
PACLEGCH_00735 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
PACLEGCH_00736 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PACLEGCH_00737 4.1e-37 ylqC L Belongs to the UPF0109 family
PACLEGCH_00738 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PACLEGCH_00739 0.0 ydaO E amino acid
PACLEGCH_00740 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
PACLEGCH_00741 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PACLEGCH_00742 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PACLEGCH_00743 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PACLEGCH_00744 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PACLEGCH_00745 7.8e-171 murB 1.3.1.98 M cell wall formation
PACLEGCH_00746 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PACLEGCH_00747 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
PACLEGCH_00748 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
PACLEGCH_00749 2.3e-206 potD P spermidine putrescine ABC transporter
PACLEGCH_00750 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
PACLEGCH_00751 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
PACLEGCH_00752 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
PACLEGCH_00753 5.1e-96 GK ROK family
PACLEGCH_00754 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PACLEGCH_00755 3.9e-104 wecD M Acetyltransferase GNAT family
PACLEGCH_00756 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PACLEGCH_00757 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
PACLEGCH_00758 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
PACLEGCH_00760 2.2e-58 lrgA S Effector of murein hydrolase LrgA
PACLEGCH_00761 2.2e-117 lrgB M effector of murein hydrolase
PACLEGCH_00762 2.8e-108 3.1.3.18 S IA, variant 1
PACLEGCH_00763 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PACLEGCH_00764 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PACLEGCH_00765 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
PACLEGCH_00766 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PACLEGCH_00767 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PACLEGCH_00768 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PACLEGCH_00769 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
PACLEGCH_00771 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
PACLEGCH_00773 3e-37 ycaO O OsmC-like protein
PACLEGCH_00774 1.2e-64 paaI Q protein possibly involved in aromatic compounds catabolism
PACLEGCH_00777 1.7e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PACLEGCH_00778 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PACLEGCH_00779 1.1e-16 XK27_00735
PACLEGCH_00780 1.4e-127 glnQ 3.6.3.21 E abc transporter atp-binding protein
PACLEGCH_00781 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
PACLEGCH_00782 7.6e-32 S CAAX amino terminal protease family protein
PACLEGCH_00783 1.2e-55 V CAAX protease self-immunity
PACLEGCH_00785 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PACLEGCH_00786 2.9e-84 mutT 3.6.1.55 F Nudix family
PACLEGCH_00787 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
PACLEGCH_00788 2.5e-136 ET ABC transporter
PACLEGCH_00789 1.4e-201 arcT 2.6.1.1 E Aminotransferase
PACLEGCH_00790 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
PACLEGCH_00791 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PACLEGCH_00792 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PACLEGCH_00793 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PACLEGCH_00794 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
PACLEGCH_00795 3.3e-172 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PACLEGCH_00796 3.3e-42
PACLEGCH_00797 3.5e-122
PACLEGCH_00798 4e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PACLEGCH_00799 1.4e-124 ycbB S Glycosyl transferase family 2
PACLEGCH_00800 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
PACLEGCH_00801 4e-221 amrA S polysaccharide biosynthetic process
PACLEGCH_00802 5.6e-186 tagF 2.7.8.12 M Glycosyl transferase, family 2
PACLEGCH_00803 7.4e-137 S Predicted membrane protein (DUF2142)
PACLEGCH_00804 8.3e-218 rgpA GT4 M Domain of unknown function (DUF1972)
PACLEGCH_00805 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
PACLEGCH_00806 2.1e-143 rgpC GM Transport permease protein
PACLEGCH_00807 5.4e-228 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PACLEGCH_00808 3.1e-301 GT4 M transferase activity, transferring glycosyl groups
PACLEGCH_00809 0.0 rgpF M Rhamnan synthesis protein F
PACLEGCH_00810 2e-31 M Psort location CytoplasmicMembrane, score
PACLEGCH_00811 3.9e-35 M Psort location CytoplasmicMembrane, score
PACLEGCH_00812 4.6e-115 radC E Belongs to the UPF0758 family
PACLEGCH_00813 1.6e-131 puuD T peptidase C26
PACLEGCH_00814 3.6e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PACLEGCH_00815 2e-58 XK27_04120 S Putative amino acid metabolism
PACLEGCH_00816 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
PACLEGCH_00817 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PACLEGCH_00818 1.5e-103 yjbK S Adenylate cyclase
PACLEGCH_00819 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
PACLEGCH_00820 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PACLEGCH_00821 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PACLEGCH_00822 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PACLEGCH_00823 1.3e-07 L Transposase and inactivated derivatives, TnpA family
PACLEGCH_00825 2.8e-175 gadC E Psort location CytoplasmicMembrane, score 10.00
PACLEGCH_00826 2.3e-214 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PACLEGCH_00827 1.3e-90 tnp L Transposase
PACLEGCH_00828 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PACLEGCH_00829 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PACLEGCH_00830 1.7e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PACLEGCH_00831 1.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PACLEGCH_00832 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PACLEGCH_00833 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PACLEGCH_00834 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PACLEGCH_00835 1.6e-126 IQ reductase
PACLEGCH_00836 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PACLEGCH_00837 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
PACLEGCH_00838 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PACLEGCH_00839 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PACLEGCH_00840 4e-72 marR K Transcriptional regulator, MarR family
PACLEGCH_00841 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
PACLEGCH_00842 1.9e-115 S Haloacid dehalogenase-like hydrolase
PACLEGCH_00843 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
PACLEGCH_00844 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
PACLEGCH_00845 1.5e-258 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PACLEGCH_00846 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
PACLEGCH_00847 7.8e-102 ygaC J Belongs to the UPF0374 family
PACLEGCH_00848 6.4e-108 S Domain of unknown function (DUF1803)
PACLEGCH_00849 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
PACLEGCH_00856 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
PACLEGCH_00857 1.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PACLEGCH_00858 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
PACLEGCH_00859 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
PACLEGCH_00860 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PACLEGCH_00861 3e-98 metI P ABC transporter (Permease
PACLEGCH_00862 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PACLEGCH_00863 3.2e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
PACLEGCH_00864 9.4e-95 S UPF0397 protein
PACLEGCH_00865 0.0 ykoD P abc transporter atp-binding protein
PACLEGCH_00866 1.2e-146 cbiQ P cobalt transport
PACLEGCH_00867 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PACLEGCH_00868 1e-12 ulaG S L-ascorbate 6-phosphate lactonase
PACLEGCH_00869 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
PACLEGCH_00870 1.5e-242 P COG0168 Trk-type K transport systems, membrane components
PACLEGCH_00871 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
PACLEGCH_00872 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
PACLEGCH_00873 5.1e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PACLEGCH_00874 2.8e-282 T PhoQ Sensor
PACLEGCH_00875 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PACLEGCH_00876 6.5e-218 dnaB L Replication initiation and membrane attachment
PACLEGCH_00877 5.2e-167 dnaI L Primosomal protein DnaI
PACLEGCH_00878 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PACLEGCH_00880 1.2e-34
PACLEGCH_00881 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
PACLEGCH_00882 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
PACLEGCH_00883 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PACLEGCH_00884 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
PACLEGCH_00885 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
PACLEGCH_00886 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PACLEGCH_00888 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PACLEGCH_00890 1.2e-61 KT phosphorelay signal transduction system
PACLEGCH_00891 7e-34 S Protein of unknown function (DUF3021)
PACLEGCH_00892 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PACLEGCH_00893 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PACLEGCH_00894 8.2e-70 argR K Regulates arginine biosynthesis genes
PACLEGCH_00895 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PACLEGCH_00896 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PACLEGCH_00897 2.3e-136 J Domain of unknown function (DUF4041)
PACLEGCH_00898 2.8e-23
PACLEGCH_00899 4.3e-138 1.1.1.169 H Ketopantoate reductase
PACLEGCH_00900 8.5e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PACLEGCH_00901 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PACLEGCH_00902 2e-241 purD 6.3.4.13 F Belongs to the GARS family
PACLEGCH_00903 2.3e-161 S CHAP domain
PACLEGCH_00910 5.3e-11
PACLEGCH_00916 1.3e-140 mreC M Involved in formation and maintenance of cell shape
PACLEGCH_00917 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
PACLEGCH_00918 5.5e-94 usp 3.5.1.28 CBM50 S CHAP domain
PACLEGCH_00919 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PACLEGCH_00920 5.9e-219 araT 2.6.1.1 E Aminotransferase
PACLEGCH_00921 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
PACLEGCH_00922 3.9e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PACLEGCH_00923 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PACLEGCH_00924 1.2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PACLEGCH_00925 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PACLEGCH_00926 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PACLEGCH_00927 3.7e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PACLEGCH_00928 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PACLEGCH_00929 7.3e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PACLEGCH_00930 2.3e-90 L transposase activity
PACLEGCH_00931 0.0 3.6.3.8 P cation transport ATPase
PACLEGCH_00932 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
PACLEGCH_00934 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PACLEGCH_00935 7.3e-166 metF 1.5.1.20 E reductase
PACLEGCH_00936 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PACLEGCH_00937 1.7e-94 panT S ECF transporter, substrate-specific component
PACLEGCH_00938 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PACLEGCH_00939 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
PACLEGCH_00940 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PACLEGCH_00941 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PACLEGCH_00942 2.8e-40 T PhoQ Sensor
PACLEGCH_00943 1.7e-43 T PhoQ Sensor
PACLEGCH_00944 5.8e-79 T PhoQ Sensor
PACLEGCH_00945 2.7e-188 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PACLEGCH_00946 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PACLEGCH_00947 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PACLEGCH_00948 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PACLEGCH_00949 1.1e-142 purR 2.4.2.7 F operon repressor
PACLEGCH_00950 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
PACLEGCH_00951 6.9e-173 rmuC S RmuC domain protein
PACLEGCH_00952 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
PACLEGCH_00953 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PACLEGCH_00954 7.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PACLEGCH_00956 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PACLEGCH_00957 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PACLEGCH_00958 4.1e-144 tatD L Hydrolase, tatd
PACLEGCH_00959 7.2e-74 yccU S CoA-binding protein
PACLEGCH_00960 4.8e-51 trxA O Belongs to the thioredoxin family
PACLEGCH_00961 6.6e-142 S Macro domain protein
PACLEGCH_00962 3.1e-10 L thioesterase
PACLEGCH_00963 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
PACLEGCH_00964 6.4e-24
PACLEGCH_00965 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PACLEGCH_00966 3e-298 hsdM 2.1.1.72 V HsdM N-terminal domain
PACLEGCH_00967 3.4e-89 3.1.21.3 V Type I restriction modification DNA specificity domain
PACLEGCH_00968 2.2e-50 3.1.21.3 V Type I restriction modification DNA specificity domain
PACLEGCH_00969 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PACLEGCH_00970 4.5e-61 cadC K helix_turn_helix, Arsenical Resistance Operon Repressor
PACLEGCH_00971 5.7e-46 S Domain of unknown function (DUF4298)
PACLEGCH_00972 4.1e-66 L Integrase
PACLEGCH_00973 1.9e-07
PACLEGCH_00978 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PACLEGCH_00979 3.1e-234 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PACLEGCH_00980 5.5e-36 XK27_02060 S Transglycosylase associated protein
PACLEGCH_00981 2.6e-55 badR K DNA-binding transcription factor activity
PACLEGCH_00982 3.5e-97 S reductase
PACLEGCH_00983 5.8e-127 S Protein conserved in bacteria
PACLEGCH_00984 7.1e-135 HJ the current gene model (or a revised gene model) may contain a frame shift
PACLEGCH_00985 3.9e-125 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PACLEGCH_00986 1.3e-12 2.3.1.82 M Acetyltransferase GNAT Family
PACLEGCH_00987 7.8e-93
PACLEGCH_00988 2.2e-111
PACLEGCH_00989 9.8e-163 L Integrase core domain protein
PACLEGCH_00990 1.1e-82 L Helix-turn-helix domain
PACLEGCH_00991 1.9e-21 L Helix-turn-helix domain
PACLEGCH_00992 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
PACLEGCH_00993 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
PACLEGCH_00994 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
PACLEGCH_00995 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PACLEGCH_00996 6.2e-56 S Domain of unknown function (DUF4430)
PACLEGCH_00997 4.2e-75 S Psort location CytoplasmicMembrane, score
PACLEGCH_00998 6.4e-133 htpX O Belongs to the peptidase M48B family
PACLEGCH_00999 9e-93 lemA S LemA family
PACLEGCH_01000 1.7e-161 spd F DNA RNA non-specific endonuclease
PACLEGCH_01001 1.8e-90 S double-stranded DNA endodeoxyribonuclease activity
PACLEGCH_01002 1.5e-49 S PD-(D/E)XK nuclease family transposase
PACLEGCH_01003 1.1e-303 hsdM 2.1.1.72 V type I restriction-modification system
PACLEGCH_01004 5e-42 K Helix-turn-helix domain
PACLEGCH_01005 3.8e-125 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain protein
PACLEGCH_01006 0.0 S Domain of unknown function DUF87
PACLEGCH_01007 1.6e-164 S SIR2-like domain
PACLEGCH_01008 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PACLEGCH_01009 1.7e-134 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PACLEGCH_01010 8e-18 MA20_36090 S Protein of unknown function (DUF2974)
PACLEGCH_01011 7.9e-37 MA20_36090 S Protein of unknown function (DUF2974)
PACLEGCH_01012 1.7e-10 MA20_36090 S Protein of unknown function (DUF2974)
PACLEGCH_01013 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PACLEGCH_01014 2.7e-27 P Hemerythrin HHE cation binding domain protein
PACLEGCH_01015 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
PACLEGCH_01016 3.9e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PACLEGCH_01017 4.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
PACLEGCH_01018 2.3e-175 S hydrolase
PACLEGCH_01019 7.6e-16
PACLEGCH_01020 1e-163 M LysM domain
PACLEGCH_01021 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PACLEGCH_01022 0.0 L helicase
PACLEGCH_01023 1.2e-67 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
PACLEGCH_01024 2.1e-11
PACLEGCH_01025 1.1e-234 mntH P H( )-stimulated, divalent metal cation uptake system
PACLEGCH_01026 1.1e-33 XK27_12190 S protein conserved in bacteria
PACLEGCH_01028 8.4e-88 bioY S biotin synthase
PACLEGCH_01029 8.1e-46 S CHY zinc finger
PACLEGCH_01030 9.8e-252 yegQ O Peptidase U32
PACLEGCH_01031 2e-177 yegQ O Peptidase U32
PACLEGCH_01033 5.5e-69 ytxH S General stress protein
PACLEGCH_01035 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PACLEGCH_01036 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PACLEGCH_01037 9.9e-42 pspC KT PspC domain
PACLEGCH_01038 0.0 yhgF K Transcriptional accessory protein
PACLEGCH_01040 2.3e-154 XK27_03015 S permease
PACLEGCH_01041 9.3e-147 ycgQ S TIGR03943 family
PACLEGCH_01042 2.6e-194 S CRISPR-associated protein Csn2 subfamily St
PACLEGCH_01043 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PACLEGCH_01044 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PACLEGCH_01045 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PACLEGCH_01046 6.8e-94
PACLEGCH_01047 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
PACLEGCH_01048 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
PACLEGCH_01049 1e-31 K Cro/C1-type HTH DNA-binding domain
PACLEGCH_01050 3.2e-46
PACLEGCH_01051 8.9e-20
PACLEGCH_01052 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PACLEGCH_01053 4.5e-97 mip S hydroperoxide reductase activity
PACLEGCH_01054 2.4e-203 I acyl-CoA dehydrogenase
PACLEGCH_01055 4.3e-156 ydiA P C4-dicarboxylate transporter malic acid transport protein
PACLEGCH_01056 5.4e-251 msrR K Transcriptional regulator
PACLEGCH_01057 6.7e-153 pheA 4.2.1.51 E Prephenate dehydratase
PACLEGCH_01058 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PACLEGCH_01059 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PACLEGCH_01060 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PACLEGCH_01061 3.2e-53 yheA S Belongs to the UPF0342 family
PACLEGCH_01062 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PACLEGCH_01063 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PACLEGCH_01064 2.9e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PACLEGCH_01065 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PACLEGCH_01066 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PACLEGCH_01067 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
PACLEGCH_01068 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PACLEGCH_01069 2e-25 WQ51_00785
PACLEGCH_01070 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PACLEGCH_01071 1e-78 yueI S Protein of unknown function (DUF1694)
PACLEGCH_01072 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PACLEGCH_01073 6.6e-101 yyaQ V Protein conserved in bacteria
PACLEGCH_01074 2.8e-28 yyaQ S YjbR
PACLEGCH_01075 4.4e-183 ccpA K Catabolite control protein A
PACLEGCH_01076 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
PACLEGCH_01077 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
PACLEGCH_01078 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PACLEGCH_01079 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PACLEGCH_01080 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PACLEGCH_01081 2e-33 secG U Preprotein translocase subunit SecG
PACLEGCH_01082 2.5e-220 mdtG EGP Major facilitator Superfamily
PACLEGCH_01083 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PACLEGCH_01084 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PACLEGCH_01085 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PACLEGCH_01086 1.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PACLEGCH_01087 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PACLEGCH_01088 6.8e-53 licT K transcriptional antiterminator
PACLEGCH_01089 5.8e-64 licT K transcriptional antiterminator
PACLEGCH_01090 4.9e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PACLEGCH_01091 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
PACLEGCH_01092 3.9e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PACLEGCH_01093 4.6e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PACLEGCH_01094 1.5e-23 I Alpha/beta hydrolase family
PACLEGCH_01095 1.5e-35 yugF I carboxylic ester hydrolase activity
PACLEGCH_01096 1.5e-07
PACLEGCH_01097 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PACLEGCH_01098 3.1e-78 feoA P FeoA domain protein
PACLEGCH_01099 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
PACLEGCH_01100 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
PACLEGCH_01101 1.3e-34 ykuJ S protein conserved in bacteria
PACLEGCH_01102 1.2e-180 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PACLEGCH_01103 0.0 clpE O Belongs to the ClpA ClpB family
PACLEGCH_01104 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PACLEGCH_01105 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
PACLEGCH_01106 9.7e-66 S oxidoreductase
PACLEGCH_01107 9.3e-59 S oxidoreductase
PACLEGCH_01108 3.4e-233 murN 2.3.2.10, 2.3.2.16 V FemAB family
PACLEGCH_01109 6.1e-70 M Pfam SNARE associated Golgi protein
PACLEGCH_01110 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
PACLEGCH_01113 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
PACLEGCH_01116 4.8e-16 S Protein of unknown function (DUF2969)
PACLEGCH_01117 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
PACLEGCH_01118 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PACLEGCH_01119 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PACLEGCH_01120 2.7e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PACLEGCH_01121 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
PACLEGCH_01122 1.4e-29 S Domain of unknown function (DUF1912)
PACLEGCH_01123 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
PACLEGCH_01124 1.3e-249 mmuP E amino acid
PACLEGCH_01125 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PACLEGCH_01126 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PACLEGCH_01127 9.7e-22
PACLEGCH_01128 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PACLEGCH_01129 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PACLEGCH_01130 1.7e-218 mvaS 2.3.3.10 I synthase
PACLEGCH_01131 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PACLEGCH_01132 1e-25 K hmm pf08876
PACLEGCH_01133 4.4e-118 yqfA K protein, Hemolysin III
PACLEGCH_01134 1.2e-22 S Protein of unknown function (DUF3114)
PACLEGCH_01135 8e-165 S Protein of unknown function (DUF3114)
PACLEGCH_01136 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PACLEGCH_01137 8.9e-57 S hydrolase activity, acting on ester bonds
PACLEGCH_01138 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PACLEGCH_01140 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PACLEGCH_01141 1.4e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
PACLEGCH_01142 1.1e-11 U protein secretion
PACLEGCH_01143 2.1e-50 U protein secretion
PACLEGCH_01144 3.5e-07 U protein secretion
PACLEGCH_01146 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PACLEGCH_01147 2.5e-21
PACLEGCH_01148 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
PACLEGCH_01149 1.5e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PACLEGCH_01150 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PACLEGCH_01151 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
PACLEGCH_01152 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PACLEGCH_01153 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PACLEGCH_01154 4.6e-105 GBS0088 J protein conserved in bacteria
PACLEGCH_01155 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PACLEGCH_01156 1e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PACLEGCH_01157 2.6e-17 ald 1.4.1.1 E alanine dehydrogenase activity
PACLEGCH_01158 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PACLEGCH_01159 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PACLEGCH_01160 2.5e-113 S VIT family
PACLEGCH_01161 1.4e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
PACLEGCH_01162 1.9e-22
PACLEGCH_01163 8e-28 XK27_00085 K Transcriptional
PACLEGCH_01164 6.9e-197 yceA S Belongs to the UPF0176 family
PACLEGCH_01165 5.4e-122 sagI S ABC-2 type transporter
PACLEGCH_01166 2.8e-168 V ABC transporter
PACLEGCH_01167 1.3e-218 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PACLEGCH_01168 2.5e-132 rr02 KT response regulator
PACLEGCH_01169 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PACLEGCH_01170 6.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PACLEGCH_01171 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PACLEGCH_01172 0.0 lmrA V abc transporter atp-binding protein
PACLEGCH_01173 0.0 mdlB V abc transporter atp-binding protein
PACLEGCH_01175 3.7e-54 L Transposase
PACLEGCH_01176 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PACLEGCH_01177 1.2e-24 oppF P Belongs to the ABC transporter superfamily
PACLEGCH_01178 1.1e-44 oppF P Belongs to the ABC transporter superfamily
PACLEGCH_01179 1.4e-40 tatD L Hydrolase, tatd
PACLEGCH_01180 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
PACLEGCH_01181 1e-110 L Integrase core domain protein
PACLEGCH_01182 4.4e-56 L Transposase IS116 IS110 IS902
PACLEGCH_01183 7.8e-135 L COG3547 Transposase and inactivated derivatives
PACLEGCH_01184 1.1e-43 J glyoxalase III activity
PACLEGCH_01185 1.7e-19 V Transport permease protein
PACLEGCH_01186 1e-40 V ABC transporter
PACLEGCH_01187 2e-17 CG UDP-glucoronosyl and UDP-glucosyl transferase
PACLEGCH_01188 1.5e-59 cysE 2.3.1.30 E serine acetyltransferase
PACLEGCH_01189 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PACLEGCH_01190 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PACLEGCH_01191 2.9e-190 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PACLEGCH_01192 1.9e-49 M YSIRK type signal peptide
PACLEGCH_01193 3e-92 S MucBP domain
PACLEGCH_01196 3.1e-268 clcA P Chloride transporter, ClC family
PACLEGCH_01197 8.9e-206 potD P spermidine putrescine ABC transporter
PACLEGCH_01198 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
PACLEGCH_01199 1.3e-51 L Helix-turn-helix domain
PACLEGCH_01200 0.0 copB 3.6.3.4 P haloacid dehalogenase-like hydrolase
PACLEGCH_01201 1.6e-18 L Integrase core domain
PACLEGCH_01202 1.5e-162 hrtB V MacB-like periplasmic core domain
PACLEGCH_01204 0.0 M family 8
PACLEGCH_01205 2.7e-09
PACLEGCH_01206 5.6e-08
PACLEGCH_01207 5.8e-109 MA20_06410 E LysE type translocator
PACLEGCH_01208 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
PACLEGCH_01209 2.8e-10 IQ PFAM AMP-dependent synthetase and ligase
PACLEGCH_01210 3.4e-126
PACLEGCH_01211 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PACLEGCH_01212 4.5e-61
PACLEGCH_01214 9.3e-72 S Signal peptide protein, YSIRK family
PACLEGCH_01215 3.1e-54 K response regulator
PACLEGCH_01216 1.1e-37 BP1961 P nitric oxide dioxygenase activity
PACLEGCH_01218 2.8e-282 XK27_07020 S Belongs to the UPF0371 family
PACLEGCH_01219 1e-181 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PACLEGCH_01220 6.8e-161 yvgN C reductase
PACLEGCH_01222 1.6e-30 yoaK S Protein of unknown function (DUF1275)
PACLEGCH_01223 1.4e-110 drgA C Nitroreductase
PACLEGCH_01224 5.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PACLEGCH_01225 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
PACLEGCH_01226 5.6e-77 ywnA K Transcriptional regulator
PACLEGCH_01227 9.5e-150 1.13.11.2 S glyoxalase
PACLEGCH_01228 5.1e-110 XK27_02070 S nitroreductase
PACLEGCH_01229 6.2e-228 yfnA E amino acid
PACLEGCH_01230 4.8e-25 csbD K CsbD-like
PACLEGCH_01231 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
PACLEGCH_01232 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
PACLEGCH_01233 4.3e-234 brnQ E Component of the transport system for branched-chain amino acids
PACLEGCH_01234 3e-183 hipO E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PACLEGCH_01235 3.2e-07 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
PACLEGCH_01236 9.9e-50 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
PACLEGCH_01237 3e-42 gldA 1.1.1.1, 1.1.1.6 C glycerol dehydrogenase
PACLEGCH_01238 6e-147 ykrV3 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PACLEGCH_01239 3e-115 yxeQ S MmgE/PrpD family
PACLEGCH_01240 5.4e-58 yxeL K Acetyltransferase (GNAT) domain
PACLEGCH_01241 4.1e-63 yxeN U ABC transporter, permease protein
PACLEGCH_01242 7.3e-93 yxeO 3.6.3.21 E abc transporter atp-binding protein
PACLEGCH_01243 2.9e-198 pcaB 4.3.2.2 F Adenylosuccinate lyase
PACLEGCH_01244 3.5e-85 yxeM ET Belongs to the bacterial solute-binding protein 3 family
PACLEGCH_01245 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PACLEGCH_01246 1.5e-247 norM V Multidrug efflux pump
PACLEGCH_01247 9.2e-119 pbuX F xanthine permease
PACLEGCH_01248 3.3e-69 pbuX F xanthine permease
PACLEGCH_01249 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PACLEGCH_01250 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PACLEGCH_01251 6.2e-166 T Histidine kinase
PACLEGCH_01252 1.9e-133 macB2 V ABC transporter, ATP-binding protein
PACLEGCH_01253 0.0 V ABC transporter (permease)
PACLEGCH_01254 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
PACLEGCH_01255 2.6e-30 liaI KT membrane
PACLEGCH_01256 1.4e-15 liaI KT membrane
PACLEGCH_01257 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
PACLEGCH_01258 3.7e-122 S An automated process has identified a potential problem with this gene model
PACLEGCH_01260 4.6e-42 3.6.1.55 F NUDIX domain
PACLEGCH_01261 1.2e-152 mutR K Transcriptional activator, Rgg GadR MutR family
PACLEGCH_01262 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
PACLEGCH_01263 3.3e-212 EGP Major facilitator Superfamily
PACLEGCH_01267 5.7e-158 XK27_09825 V abc transporter atp-binding protein
PACLEGCH_01268 1.5e-132 yvfS V ABC-2 type transporter
PACLEGCH_01269 1.5e-192 desK 2.7.13.3 T Histidine kinase
PACLEGCH_01270 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PACLEGCH_01271 9.5e-98 S transport system, permease component
PACLEGCH_01272 3.5e-33 S transport system, permease component
PACLEGCH_01273 9.3e-144 S ABC-2 family transporter protein
PACLEGCH_01274 7.4e-26
PACLEGCH_01275 9.6e-150 sdaAA 4.3.1.17 E L-serine dehydratase
PACLEGCH_01276 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
PACLEGCH_01277 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
PACLEGCH_01278 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PACLEGCH_01279 6.9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PACLEGCH_01280 3e-13
PACLEGCH_01281 2.8e-93 pat 2.3.1.183 M acetyltransferase
PACLEGCH_01282 4.7e-87 alkD L Dna alkylation repair
PACLEGCH_01283 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PACLEGCH_01284 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PACLEGCH_01285 3.2e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PACLEGCH_01286 0.0 smc D Required for chromosome condensation and partitioning
PACLEGCH_01287 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PACLEGCH_01288 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PACLEGCH_01289 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PACLEGCH_01291 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
PACLEGCH_01292 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PACLEGCH_01294 2e-86 S ECF-type riboflavin transporter, S component
PACLEGCH_01295 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PACLEGCH_01296 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PACLEGCH_01297 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
PACLEGCH_01298 2.5e-294 yfmM S abc transporter atp-binding protein
PACLEGCH_01299 2.6e-258 noxE P NADH oxidase
PACLEGCH_01300 2.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PACLEGCH_01301 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PACLEGCH_01302 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PACLEGCH_01303 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
PACLEGCH_01304 1.8e-165 ypuA S secreted protein
PACLEGCH_01305 3.3e-26 L Transposase (IS116 IS110 IS902 family)
PACLEGCH_01306 4.2e-71 L Transposase (IS116 IS110 IS902 family)
PACLEGCH_01308 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PACLEGCH_01309 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PACLEGCH_01310 2.2e-34 nrdH O Glutaredoxin
PACLEGCH_01311 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PACLEGCH_01312 1.5e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
PACLEGCH_01313 7.4e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
PACLEGCH_01314 7.9e-39 ptsH G phosphocarrier protein Hpr
PACLEGCH_01315 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PACLEGCH_01316 8.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PACLEGCH_01317 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PACLEGCH_01318 2.1e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
PACLEGCH_01319 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
PACLEGCH_01320 0.0 uup S abc transporter atp-binding protein
PACLEGCH_01321 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
PACLEGCH_01322 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PACLEGCH_01323 8.7e-150 cobQ S glutamine amidotransferase
PACLEGCH_01324 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
PACLEGCH_01325 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PACLEGCH_01326 6e-169 ybbR S Protein conserved in bacteria
PACLEGCH_01327 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PACLEGCH_01328 1.7e-70 gtrA S GtrA-like protein
PACLEGCH_01329 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
PACLEGCH_01330 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PACLEGCH_01331 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
PACLEGCH_01332 2.9e-204 yurR 1.4.5.1 E oxidoreductase
PACLEGCH_01333 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PACLEGCH_01334 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PACLEGCH_01335 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PACLEGCH_01338 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
PACLEGCH_01339 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
PACLEGCH_01340 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PACLEGCH_01341 1.1e-121 ylfI S tigr01906
PACLEGCH_01342 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PACLEGCH_01343 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PACLEGCH_01344 5e-71 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PACLEGCH_01345 1.3e-22 XK27_08085
PACLEGCH_01346 2.6e-89 devA 3.6.3.25 V abc transporter atp-binding protein
PACLEGCH_01347 1.4e-192 wbbI M transferase activity, transferring glycosyl groups
PACLEGCH_01348 4.1e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
PACLEGCH_01349 1.6e-242 epsU S Polysaccharide biosynthesis protein
PACLEGCH_01350 1.4e-100 cps3F
PACLEGCH_01351 3.4e-135 M Glycosyltransferase like family 2
PACLEGCH_01352 3.4e-119 M Glycosyltransferase, group 2 family protein
PACLEGCH_01354 2.6e-135 M transferase activity, transferring glycosyl groups
PACLEGCH_01355 3.4e-211 wcoF M Glycosyltransferase, group 1 family protein
PACLEGCH_01356 5.3e-220 rgpAc GT4 M group 1 family protein
PACLEGCH_01357 5.2e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PACLEGCH_01358 1.1e-117 cpsD D COG0489 ATPases involved in chromosome partitioning
PACLEGCH_01359 2.6e-110 cps4C M biosynthesis protein
PACLEGCH_01360 1.3e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
PACLEGCH_01361 1.5e-251 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
PACLEGCH_01362 9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
PACLEGCH_01363 1.5e-119 yfeJ 6.3.5.2 F glutamine amidotransferase
PACLEGCH_01364 7.3e-41 clcA_2 P chloride
PACLEGCH_01365 3.8e-42 clcA_2 P chloride channel
PACLEGCH_01366 5.8e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PACLEGCH_01367 1.3e-41 S Protein of unknown function (DUF1697)
PACLEGCH_01368 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PACLEGCH_01369 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PACLEGCH_01371 4e-21 V Glucan-binding protein C
PACLEGCH_01372 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
PACLEGCH_01373 2.9e-273 pepV 3.5.1.18 E Dipeptidase
PACLEGCH_01374 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PACLEGCH_01375 6.5e-84 XK27_03610 K Gnat family
PACLEGCH_01376 2.2e-84 L Transposase
PACLEGCH_01377 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PACLEGCH_01378 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PACLEGCH_01379 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PACLEGCH_01380 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PACLEGCH_01381 2.8e-18 M LysM domain
PACLEGCH_01382 2.9e-90 ebsA S Family of unknown function (DUF5322)
PACLEGCH_01383 4.2e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PACLEGCH_01384 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PACLEGCH_01385 2.4e-223 G COG0457 FOG TPR repeat
PACLEGCH_01386 8.1e-176 yubA S permease
PACLEGCH_01387 3.5e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
PACLEGCH_01388 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PACLEGCH_01389 2.5e-124 ftsE D cell division ATP-binding protein FtsE
PACLEGCH_01390 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PACLEGCH_01391 2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PACLEGCH_01392 1.7e-164 yjjH S Calcineurin-like phosphoesterase
PACLEGCH_01393 3.3e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PACLEGCH_01394 0.0 pacL 3.6.3.8 P cation transport ATPase
PACLEGCH_01395 3.4e-67 ywiB S Domain of unknown function (DUF1934)
PACLEGCH_01396 2.4e-44 XK27_00115 2.3.1.128 K acetyltransferase
PACLEGCH_01397 2.3e-26 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
PACLEGCH_01398 9.2e-147 yidA S hydrolases of the HAD superfamily
PACLEGCH_01399 3.4e-230 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
PACLEGCH_01400 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
PACLEGCH_01401 5.8e-247 vicK 2.7.13.3 T Histidine kinase
PACLEGCH_01402 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PACLEGCH_01403 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
PACLEGCH_01404 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PACLEGCH_01405 8e-115 gltJ P ABC transporter (Permease
PACLEGCH_01406 3.8e-111 tcyB_2 P ABC transporter (permease)
PACLEGCH_01407 7e-124 endA F DNA RNA non-specific endonuclease
PACLEGCH_01408 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
PACLEGCH_01409 2.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PACLEGCH_01411 6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PACLEGCH_01412 3.1e-130 G Domain of unknown function (DUF4832)
PACLEGCH_01413 1.6e-33 P VTC domain
PACLEGCH_01414 3.9e-47 P VTC domain
PACLEGCH_01415 1.9e-218 cotH M CotH kinase protein
PACLEGCH_01416 1.2e-184 pelG M Putative exopolysaccharide Exporter (EPS-E)
PACLEGCH_01417 3.2e-272 pelF GT4 M Domain of unknown function (DUF3492)
PACLEGCH_01418 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
PACLEGCH_01419 2.6e-166
PACLEGCH_01420 0.0 5.1.3.2 GM Psort location CytoplasmicMembrane, score
PACLEGCH_01421 6e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PACLEGCH_01422 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PACLEGCH_01423 7.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PACLEGCH_01424 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
PACLEGCH_01425 1.9e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PACLEGCH_01426 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
PACLEGCH_01429 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PACLEGCH_01430 3.2e-220 XK27_05110 P chloride
PACLEGCH_01431 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
PACLEGCH_01432 1.3e-282 clcA P Chloride transporter, ClC family
PACLEGCH_01433 6.7e-75 fld C Flavodoxin
PACLEGCH_01435 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
PACLEGCH_01436 3.9e-150 estA CE1 S Putative esterase
PACLEGCH_01437 4.3e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PACLEGCH_01438 4.4e-135 XK27_08845 S abc transporter atp-binding protein
PACLEGCH_01439 1.5e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
PACLEGCH_01440 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
PACLEGCH_01441 3.2e-17 S Domain of unknown function (DUF4649)
PACLEGCH_01443 4.8e-12 Q the current gene model (or a revised gene model) may contain a frame shift
PACLEGCH_01444 9.4e-14 Q the current gene model (or a revised gene model) may contain a frame shift
PACLEGCH_01445 8.3e-10 Q the current gene model (or a revised gene model) may contain a frame shift
PACLEGCH_01446 9.3e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PACLEGCH_01447 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PACLEGCH_01448 0.0 dnaE 2.7.7.7 L DNA polymerase
PACLEGCH_01449 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
PACLEGCH_01450 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PACLEGCH_01451 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PACLEGCH_01452 2.5e-43 ysdA L Membrane
PACLEGCH_01453 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PACLEGCH_01454 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PACLEGCH_01455 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PACLEGCH_01456 2.1e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PACLEGCH_01458 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PACLEGCH_01459 1.7e-83 ypmS S Protein conserved in bacteria
PACLEGCH_01460 6e-144 ypmR E lipolytic protein G-D-S-L family
PACLEGCH_01461 1e-148 DegV S DegV family
PACLEGCH_01462 2.2e-304 recN L May be involved in recombinational repair of damaged DNA
PACLEGCH_01463 3.7e-73 argR K Regulates arginine biosynthesis genes
PACLEGCH_01464 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PACLEGCH_01465 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PACLEGCH_01466 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
PACLEGCH_01467 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PACLEGCH_01470 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PACLEGCH_01471 2.9e-125 dnaD
PACLEGCH_01472 4.6e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PACLEGCH_01473 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PACLEGCH_01474 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
PACLEGCH_01475 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PACLEGCH_01476 2e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PACLEGCH_01477 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PACLEGCH_01478 7.8e-222 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PACLEGCH_01479 3.6e-239 rodA D Belongs to the SEDS family
PACLEGCH_01480 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
PACLEGCH_01481 9.4e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PACLEGCH_01482 8.9e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PACLEGCH_01483 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PACLEGCH_01484 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PACLEGCH_01485 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PACLEGCH_01486 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PACLEGCH_01487 4e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PACLEGCH_01488 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PACLEGCH_01489 4.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PACLEGCH_01491 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PACLEGCH_01492 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PACLEGCH_01493 8.2e-28 ytrF V efflux transmembrane transporter activity
PACLEGCH_01494 1.7e-29 V efflux transmembrane transporter activity
PACLEGCH_01495 1.5e-18 V permease protein
PACLEGCH_01496 6.2e-38 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PACLEGCH_01497 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PACLEGCH_01498 4.6e-132 2.1.1.223 S Putative SAM-dependent methyltransferase
PACLEGCH_01499 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
PACLEGCH_01500 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
PACLEGCH_01501 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PACLEGCH_01502 4.9e-227 pyrP F uracil Permease
PACLEGCH_01503 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PACLEGCH_01504 4.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PACLEGCH_01505 9.8e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PACLEGCH_01506 9e-167 fhuR K transcriptional regulator (lysR family)
PACLEGCH_01511 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PACLEGCH_01512 1.1e-75 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
PACLEGCH_01513 2.5e-119 pts33BCA G pts system
PACLEGCH_01514 1.7e-70 pts33BCA G pts system
PACLEGCH_01515 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
PACLEGCH_01516 1.8e-254 cycA E permease
PACLEGCH_01517 4.5e-39 ynzC S UPF0291 protein
PACLEGCH_01518 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PACLEGCH_01519 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PACLEGCH_01520 6.1e-63 S membrane
PACLEGCH_01521 1.5e-59
PACLEGCH_01522 7.5e-26
PACLEGCH_01523 1.8e-53
PACLEGCH_01524 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PACLEGCH_01525 3.5e-69 nptA P sodium-dependent phosphate transmembrane transporter activity
PACLEGCH_01526 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
PACLEGCH_01527 4.9e-106 mur1 NU mannosyl-glycoprotein
PACLEGCH_01528 3.6e-52 glnB K Belongs to the P(II) protein family
PACLEGCH_01529 4e-226 amt P Ammonium Transporter
PACLEGCH_01530 3.9e-159 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PACLEGCH_01531 9.5e-55 yabA L Involved in initiation control of chromosome replication
PACLEGCH_01532 3.1e-134 yaaT S stage 0 sporulation protein
PACLEGCH_01533 6.4e-162 holB 2.7.7.7 L dna polymerase iii
PACLEGCH_01534 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PACLEGCH_01535 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PACLEGCH_01536 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PACLEGCH_01537 2.8e-230 ftsW D Belongs to the SEDS family
PACLEGCH_01538 6.8e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PACLEGCH_01539 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PACLEGCH_01540 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PACLEGCH_01541 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PACLEGCH_01542 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PACLEGCH_01543 3.3e-78 atpF C ATP synthase F(0) sector subunit b
PACLEGCH_01544 3.1e-122 atpB C it plays a direct role in the translocation of protons across the membrane
PACLEGCH_01545 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PACLEGCH_01546 9.5e-265
PACLEGCH_01547 4.1e-215 dcm 2.1.1.37 H cytosine-specific methyltransferase
PACLEGCH_01548 5.3e-34
PACLEGCH_01549 0.0 yfjK F helicase superfamily c-terminal domain
PACLEGCH_01550 6e-118 S Domain of unknown function (DUF1837)
PACLEGCH_01551 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PACLEGCH_01552 5.3e-74 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PACLEGCH_01553 5.7e-106 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PACLEGCH_01554 8.9e-14 coiA 3.6.4.12 S Competence protein
PACLEGCH_01555 2.6e-16 T peptidase
PACLEGCH_01556 2.3e-151 rarD S Transporter
PACLEGCH_01557 1.1e-153 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PACLEGCH_01558 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PACLEGCH_01559 6.5e-130 yxkH G deacetylase
PACLEGCH_01560 5.3e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PACLEGCH_01561 1.2e-129 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PACLEGCH_01562 2.6e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PACLEGCH_01563 8.5e-190 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PACLEGCH_01564 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PACLEGCH_01565 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PACLEGCH_01566 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
PACLEGCH_01567 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PACLEGCH_01568 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PACLEGCH_01569 3.8e-175 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
PACLEGCH_01570 1.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
PACLEGCH_01571 0.0 pepF E oligoendopeptidase F
PACLEGCH_01572 1.4e-186 coiA 3.6.4.12 S Competence protein
PACLEGCH_01573 1.8e-164 K transcriptional regulator (lysR family)
PACLEGCH_01574 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PACLEGCH_01578 8e-191 phoH T phosphate starvation-inducible protein PhoH
PACLEGCH_01579 2.3e-61 rlpA M LysM domain protein
PACLEGCH_01580 1.8e-122 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
PACLEGCH_01581 7.4e-35 yozE S Belongs to the UPF0346 family
PACLEGCH_01582 5.3e-161 cvfB S Protein conserved in bacteria
PACLEGCH_01583 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PACLEGCH_01584 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PACLEGCH_01585 3.2e-78 sptS 2.7.13.3 T Histidine kinase
PACLEGCH_01586 5.4e-45 K Acetyltransferase (GNAT) family
PACLEGCH_01587 0.0 lmrA2 V abc transporter atp-binding protein
PACLEGCH_01588 0.0 lmrA1 V abc transporter atp-binding protein
PACLEGCH_01589 1.9e-77 K DNA-binding transcription factor activity
PACLEGCH_01590 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PACLEGCH_01591 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PACLEGCH_01592 1.7e-162 L Transposase
PACLEGCH_01593 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PACLEGCH_01594 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PACLEGCH_01595 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PACLEGCH_01596 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
PACLEGCH_01598 2.7e-61 divIC D Septum formation initiator
PACLEGCH_01599 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PACLEGCH_01600 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PACLEGCH_01601 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PACLEGCH_01602 1.9e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PACLEGCH_01603 1.1e-29 yyzM S Protein conserved in bacteria
PACLEGCH_01604 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PACLEGCH_01605 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PACLEGCH_01606 8.5e-134 parB K Belongs to the ParB family
PACLEGCH_01607 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PACLEGCH_01608 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PACLEGCH_01609 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
PACLEGCH_01613 0.0 XK27_10405 S Bacterial membrane protein YfhO
PACLEGCH_01614 6.7e-306 ybiT S abc transporter atp-binding protein
PACLEGCH_01615 4.2e-153 yvjA S membrane
PACLEGCH_01616 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PACLEGCH_01617 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PACLEGCH_01618 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PACLEGCH_01619 1.6e-45 yaaA S S4 domain protein YaaA
PACLEGCH_01620 4e-234 ymfF S Peptidase M16
PACLEGCH_01621 4e-38 ymfH S Peptidase M16
PACLEGCH_01622 1.5e-178 ymfH S Peptidase M16
PACLEGCH_01623 1.8e-137 ymfM S sequence-specific DNA binding
PACLEGCH_01624 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PACLEGCH_01625 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PACLEGCH_01626 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PACLEGCH_01627 2.2e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PACLEGCH_01628 5.3e-85 lytE M LysM domain protein
PACLEGCH_01629 5e-61 isaA GH23 M Immunodominant staphylococcal antigen A
PACLEGCH_01630 0.0 S Bacterial membrane protein, YfhO
PACLEGCH_01631 2.1e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PACLEGCH_01632 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PACLEGCH_01633 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PACLEGCH_01634 3.9e-70 rplI J binds to the 23S rRNA
PACLEGCH_01635 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PACLEGCH_01636 8.2e-48 veg S Biofilm formation stimulator VEG
PACLEGCH_01637 2.9e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PACLEGCH_01638 6.4e-141 sip L Phage integrase, N-terminal SAM-like domain
PACLEGCH_01639 1.4e-12 K sequence-specific DNA binding
PACLEGCH_01640 3.4e-12 K Helix-turn-helix
PACLEGCH_01641 6.7e-17
PACLEGCH_01642 3.8e-13
PACLEGCH_01643 6.5e-266
PACLEGCH_01649 2.8e-27 S Transcriptional regulator, RinA family
PACLEGCH_01650 4.4e-18 yjgN S membrane
PACLEGCH_01653 2e-07
PACLEGCH_01654 4.8e-55 ypaA M Membrane
PACLEGCH_01655 6.4e-96 XK27_06935 K transcriptional regulator
PACLEGCH_01656 3.9e-161 XK27_06930 V domain protein
PACLEGCH_01657 1.8e-88 S Putative adhesin
PACLEGCH_01658 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
PACLEGCH_01660 1.7e-23 K negative regulation of transcription, DNA-templated
PACLEGCH_01661 4e-19 K negative regulation of transcription, DNA-templated
PACLEGCH_01662 3.4e-13 nudL L hydrolase
PACLEGCH_01663 3.5e-97 nudL L hydrolase
PACLEGCH_01664 4.9e-12 K CsbD-like
PACLEGCH_01665 4.3e-71 M Protein conserved in bacteria
PACLEGCH_01666 1.8e-23 S Small integral membrane protein
PACLEGCH_01667 3.1e-101
PACLEGCH_01668 3.7e-27 S Membrane
PACLEGCH_01670 2.7e-95 S Hydrophobic domain protein
PACLEGCH_01671 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
PACLEGCH_01674 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PACLEGCH_01675 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PACLEGCH_01676 1.4e-36 metE 2.1.1.14 E Methionine synthase
PACLEGCH_01677 4.4e-54 metE 2.1.1.14 E Methionine synthase
PACLEGCH_01678 3e-53 metE 2.1.1.14 E Methionine synthase
PACLEGCH_01679 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
PACLEGCH_01681 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PACLEGCH_01682 2.7e-166 XK27_01785 S cog cog1284
PACLEGCH_01683 4.1e-147 yaaA S Belongs to the UPF0246 family
PACLEGCH_01684 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PACLEGCH_01685 2.6e-91 XK27_10930 K acetyltransferase
PACLEGCH_01686 7.5e-14
PACLEGCH_01687 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PACLEGCH_01688 4e-298 ccs S the current gene model (or a revised gene model) may contain a frame shift
PACLEGCH_01689 4.2e-44 yrzB S Belongs to the UPF0473 family
PACLEGCH_01690 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PACLEGCH_01691 2.8e-44 yrzL S Belongs to the UPF0297 family
PACLEGCH_01692 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PACLEGCH_01693 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
PACLEGCH_01695 2.2e-132 int L Belongs to the 'phage' integrase family
PACLEGCH_01696 2.5e-89 K sequence-specific DNA binding
PACLEGCH_01697 5.1e-287 V ABC transporter transmembrane region
PACLEGCH_01698 1.3e-159 C Radical SAM
PACLEGCH_01699 1.6e-53 C Radical SAM
PACLEGCH_01701 7e-127 Z012_04635 K sequence-specific DNA binding
PACLEGCH_01702 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PACLEGCH_01703 2.1e-280 V ABC transporter
PACLEGCH_01704 0.0 KLT serine threonine protein kinase
PACLEGCH_01705 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PACLEGCH_01708 5.7e-95 ywlG S Belongs to the UPF0340 family
PACLEGCH_01709 1.2e-85 treR K trehalose operon
PACLEGCH_01710 5.8e-21 treR K DNA-binding transcription factor activity
PACLEGCH_01711 1.4e-54 treB 2.7.1.201 G PTS System
PACLEGCH_01712 5.6e-64 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PACLEGCH_01713 4.1e-70 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PACLEGCH_01714 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PACLEGCH_01715 0.0 pepO 3.4.24.71 O Peptidase family M13
PACLEGCH_01716 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
PACLEGCH_01717 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PACLEGCH_01718 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PACLEGCH_01719 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
PACLEGCH_01720 3.2e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PACLEGCH_01721 1.9e-278 thrC 4.2.3.1 E Threonine synthase
PACLEGCH_01722 7.1e-226 norN V Mate efflux family protein
PACLEGCH_01723 1.8e-57 asp S cog cog1302
PACLEGCH_01724 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
PACLEGCH_01725 3.3e-11 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PACLEGCH_01726 8.8e-281 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PACLEGCH_01727 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
PACLEGCH_01728 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
PACLEGCH_01729 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PACLEGCH_01730 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PACLEGCH_01731 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PACLEGCH_01732 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PACLEGCH_01733 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PACLEGCH_01734 3.2e-67 S cog cog4699
PACLEGCH_01735 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PACLEGCH_01736 4.5e-152 cglB NU type II secretion system
PACLEGCH_01737 2.5e-42 comGC U Required for transformation and DNA binding
PACLEGCH_01738 2.6e-56 cglD NU Competence protein
PACLEGCH_01739 1.4e-15 NU Type II secretory pathway pseudopilin
PACLEGCH_01740 1.3e-70 comGF U Competence protein ComGF
PACLEGCH_01741 2.2e-11 comGF U Putative Competence protein ComGF
PACLEGCH_01742 4.2e-175 ytxK 2.1.1.72 L DNA methylase
PACLEGCH_01743 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PACLEGCH_01744 7.5e-26 lanR K sequence-specific DNA binding
PACLEGCH_01745 1.3e-31 V CAAX protease self-immunity
PACLEGCH_01746 4.2e-66 V CAAX protease self-immunity
PACLEGCH_01748 3.3e-110 S CAAX amino terminal protease family protein
PACLEGCH_01749 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PACLEGCH_01750 3.7e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PACLEGCH_01751 1.8e-09 S Domain of unknown function (DUF4651)
PACLEGCH_01752 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PACLEGCH_01753 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PACLEGCH_01754 1.3e-190 yeeE S Sulphur transport
PACLEGCH_01755 6.4e-37 yeeD O sulfur carrier activity
PACLEGCH_01756 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PACLEGCH_01757 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PACLEGCH_01759 2e-157 rrmA 2.1.1.187 Q methyltransferase
PACLEGCH_01760 3.4e-64 S phosphatase activity
PACLEGCH_01761 2.7e-48 S glycolate biosynthetic process
PACLEGCH_01762 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PACLEGCH_01763 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PACLEGCH_01764 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PACLEGCH_01765 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PACLEGCH_01766 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PACLEGCH_01767 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PACLEGCH_01768 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
PACLEGCH_01769 3.2e-62 fnt P Formate nitrite transporter
PACLEGCH_01770 4.4e-117 XK27_09615 C reductase
PACLEGCH_01771 2.1e-32 XK27_09615 S FMN reductase (NADPH) activity
PACLEGCH_01772 4.3e-77 XK27_09620 S reductase
PACLEGCH_01773 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
PACLEGCH_01774 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PACLEGCH_01775 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PACLEGCH_01776 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
PACLEGCH_01777 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
PACLEGCH_01778 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
PACLEGCH_01779 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PACLEGCH_01780 9.2e-51 S Protein of unknown function (DUF3397)
PACLEGCH_01781 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PACLEGCH_01782 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PACLEGCH_01783 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
PACLEGCH_01784 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
PACLEGCH_01785 2e-41 amiA E transmembrane transport
PACLEGCH_01786 6.7e-81 amiA E transmembrane transport
PACLEGCH_01787 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PACLEGCH_01788 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PACLEGCH_01789 5.4e-264 argH 4.3.2.1 E Argininosuccinate lyase
PACLEGCH_01790 1.2e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PACLEGCH_01791 1.7e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PACLEGCH_01792 5.5e-184 jag S RNA-binding protein
PACLEGCH_01793 1e-13 rpmH J Ribosomal protein L34
PACLEGCH_01794 5e-84 L Transposase
PACLEGCH_01795 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PACLEGCH_01798 4.7e-43
PACLEGCH_01799 6.8e-56 S TM2 domain
PACLEGCH_01800 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PACLEGCH_01801 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PACLEGCH_01802 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
PACLEGCH_01803 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
PACLEGCH_01804 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
PACLEGCH_01805 6e-55 cof Q phosphatase activity
PACLEGCH_01806 1.1e-34 cof Q phosphatase activity
PACLEGCH_01807 4.5e-135 glcR K transcriptional regulator (DeoR family)
PACLEGCH_01808 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PACLEGCH_01809 3.8e-40 K transcriptional
PACLEGCH_01811 2.6e-76 S thiolester hydrolase activity
PACLEGCH_01812 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
PACLEGCH_01813 9.6e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PACLEGCH_01814 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PACLEGCH_01815 3.2e-77 yhaI L Membrane
PACLEGCH_01816 4.6e-260 pepC 3.4.22.40 E aminopeptidase
PACLEGCH_01817 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PACLEGCH_01818 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PACLEGCH_01819 3.1e-95 ypsA S Belongs to the UPF0398 family
PACLEGCH_01820 2.5e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PACLEGCH_01821 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PACLEGCH_01822 2.5e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PACLEGCH_01823 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
PACLEGCH_01824 2.5e-23
PACLEGCH_01825 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PACLEGCH_01826 7.3e-80 XK27_09675 K -acetyltransferase
PACLEGCH_01827 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PACLEGCH_01828 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PACLEGCH_01829 4.9e-57 L Integrase core domain protein
PACLEGCH_01830 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PACLEGCH_01831 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PACLEGCH_01832 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PACLEGCH_01833 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
PACLEGCH_01834 1.5e-97 ybhL S Belongs to the BI1 family
PACLEGCH_01837 2.8e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PACLEGCH_01838 1.4e-90 K transcriptional regulator
PACLEGCH_01839 7.6e-36 yneF S UPF0154 protein
PACLEGCH_01840 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PACLEGCH_01841 3.2e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PACLEGCH_01842 3.5e-99 XK27_09740 S Phosphoesterase
PACLEGCH_01843 5.4e-86 ykuL S CBS domain
PACLEGCH_01844 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PACLEGCH_01845 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PACLEGCH_01846 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PACLEGCH_01847 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PACLEGCH_01848 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PACLEGCH_01849 2.1e-258 trkH P Cation transport protein
PACLEGCH_01850 6.5e-246 trkA P Potassium transporter peripheral membrane component
PACLEGCH_01851 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PACLEGCH_01852 3.9e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PACLEGCH_01853 2.4e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
PACLEGCH_01854 2.5e-161 K sequence-specific DNA binding
PACLEGCH_01855 1.9e-33 V protein secretion by the type I secretion system
PACLEGCH_01856 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PACLEGCH_01857 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PACLEGCH_01858 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PACLEGCH_01859 3.7e-22 yhaI L Membrane
PACLEGCH_01860 1.4e-54 S Domain of unknown function (DUF4173)
PACLEGCH_01861 6.8e-95 ureI S AmiS/UreI family transporter
PACLEGCH_01862 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PACLEGCH_01863 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PACLEGCH_01864 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PACLEGCH_01865 6.6e-78 ureE O enzyme active site formation
PACLEGCH_01866 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PACLEGCH_01867 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PACLEGCH_01868 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PACLEGCH_01869 2.7e-177 cbiM P PDGLE domain
PACLEGCH_01870 1.1e-136 P cobalt transport protein
PACLEGCH_01871 1.6e-131 cbiO P ABC transporter
PACLEGCH_01872 5.3e-153 ET amino acid transport
PACLEGCH_01873 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PACLEGCH_01874 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
PACLEGCH_01875 3.8e-205 EGP Transmembrane secretion effector
PACLEGCH_01876 9.9e-19 S Domain of unknown function (DUF4649)
PACLEGCH_01877 2.8e-52 amd 3.5.1.47 E Peptidase dimerisation domain
PACLEGCH_01878 2.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PACLEGCH_01879 2.9e-87
PACLEGCH_01880 1.6e-77 sigH K DNA-templated transcription, initiation
PACLEGCH_01881 3.5e-149 ykuT M mechanosensitive ion channel
PACLEGCH_01882 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PACLEGCH_01883 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PACLEGCH_01884 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PACLEGCH_01885 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
PACLEGCH_01886 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
PACLEGCH_01887 2e-177 prmA J Ribosomal protein L11 methyltransferase
PACLEGCH_01888 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PACLEGCH_01889 1.4e-42 F nucleotide catabolic process
PACLEGCH_01890 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PACLEGCH_01891 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PACLEGCH_01892 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PACLEGCH_01893 1.8e-83 nrdI F Belongs to the NrdI family
PACLEGCH_01894 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PACLEGCH_01895 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PACLEGCH_01896 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PACLEGCH_01897 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PACLEGCH_01898 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PACLEGCH_01899 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PACLEGCH_01900 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PACLEGCH_01901 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PACLEGCH_01902 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PACLEGCH_01903 6.5e-202 yhjX P Major Facilitator
PACLEGCH_01904 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PACLEGCH_01905 5e-94 V VanZ like family
PACLEGCH_01907 1e-123 glnQ E abc transporter atp-binding protein
PACLEGCH_01908 5.8e-275 glnP P ABC transporter
PACLEGCH_01909 5.9e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PACLEGCH_01910 3.4e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PACLEGCH_01911 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
PACLEGCH_01912 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PACLEGCH_01913 6.3e-235 sufD O assembly protein SufD
PACLEGCH_01914 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PACLEGCH_01915 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
PACLEGCH_01916 2.2e-273 sufB O assembly protein SufB
PACLEGCH_01917 7e-10 oppA E ABC transporter substrate-binding protein
PACLEGCH_01918 3.3e-138 oppA E ABC transporter substrate-binding protein
PACLEGCH_01919 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PACLEGCH_01920 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PACLEGCH_01921 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PACLEGCH_01922 9.8e-40 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PACLEGCH_01923 8e-28 oppD P Belongs to the ABC transporter superfamily
PACLEGCH_01924 2.5e-32 oppD P Belongs to the ABC transporter superfamily
PACLEGCH_01925 1.7e-61 oppD P Belongs to the ABC transporter superfamily
PACLEGCH_01926 3.1e-43 oppD P Belongs to the ABC transporter superfamily
PACLEGCH_01927 7.5e-62 oppF P Belongs to the ABC transporter superfamily
PACLEGCH_01928 1.2e-91 oppF P Belongs to the ABC transporter superfamily
PACLEGCH_01931 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PACLEGCH_01932 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PACLEGCH_01933 1.9e-223 EGP Major facilitator Superfamily
PACLEGCH_01934 3.1e-72 adcR K transcriptional
PACLEGCH_01935 2.2e-136 adcC P ABC transporter, ATP-binding protein
PACLEGCH_01936 1.6e-127 adcB P ABC transporter (Permease
PACLEGCH_01937 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PACLEGCH_01938 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
PACLEGCH_01939 7e-199 ptsG 2.7.1.199, 2.7.1.208 G pts system
PACLEGCH_01940 7.4e-22 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PACLEGCH_01941 7.8e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
PACLEGCH_01942 2.4e-256 pgi 5.3.1.9 G Belongs to the GPI family
PACLEGCH_01943 1.9e-127 yeeN K transcriptional regulatory protein
PACLEGCH_01944 9.8e-50 yajC U protein transport
PACLEGCH_01945 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PACLEGCH_01946 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
PACLEGCH_01947 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PACLEGCH_01948 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PACLEGCH_01949 0.0 WQ51_06230 S ABC transporter substrate binding protein
PACLEGCH_01950 5.2e-142 cmpC S abc transporter atp-binding protein
PACLEGCH_01951 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PACLEGCH_01952 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PACLEGCH_01953 4.4e-37 L Transposase
PACLEGCH_01954 6.4e-18 L transposase activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)