ORF_ID e_value Gene_name EC_number CAZy COGs Description
NMPABLHK_00001 6.9e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NMPABLHK_00002 9.4e-223 amrA S membrane protein involved in the export of O-antigen and teichoic acid
NMPABLHK_00003 9.3e-186 S Glycosyltransferase like family 2
NMPABLHK_00004 9.5e-183 cpsIaJ S Glycosyltransferase like family 2
NMPABLHK_00005 6.9e-130 arnC M group 2 family protein
NMPABLHK_00006 4.6e-42 S Uncharacterized conserved protein (DUF2304)
NMPABLHK_00007 8.2e-153 2.4.1.60 S Glycosyltransferase group 2 family protein
NMPABLHK_00008 1.8e-228 rgpA GT4 M Domain of unknown function (DUF1972)
NMPABLHK_00009 4.9e-176 rgpB GT2 M Glycosyltransferase, group 2 family protein
NMPABLHK_00010 2.1e-143 rgpC GM Transport permease protein
NMPABLHK_00011 6.4e-229 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NMPABLHK_00012 2e-305 GT4 M transferase activity, transferring glycosyl groups
NMPABLHK_00013 0.0 rgpF M Rhamnan synthesis protein F
NMPABLHK_00014 1.7e-268 M Psort location CytoplasmicMembrane, score
NMPABLHK_00015 1.2e-115 radC E Belongs to the UPF0758 family
NMPABLHK_00016 7.2e-132 puuD T peptidase C26
NMPABLHK_00017 3.3e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMPABLHK_00018 3.1e-59 XK27_04120 S Putative amino acid metabolism
NMPABLHK_00019 2.4e-206 iscS 2.8.1.7 E Cysteine desulfurase
NMPABLHK_00020 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMPABLHK_00021 1.5e-103 yjbK S Adenylate cyclase
NMPABLHK_00022 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
NMPABLHK_00023 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMPABLHK_00024 9.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NMPABLHK_00025 8.2e-182 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NMPABLHK_00026 1.7e-38 L transposase activity
NMPABLHK_00027 4.3e-23 L Transposase
NMPABLHK_00028 3e-27 L Integrase core domain protein
NMPABLHK_00029 1.2e-34
NMPABLHK_00031 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NMPABLHK_00032 5.2e-167 dnaI L Primosomal protein DnaI
NMPABLHK_00033 6.5e-218 dnaB L Replication initiation and membrane attachment
NMPABLHK_00034 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMPABLHK_00035 2.8e-282 T PhoQ Sensor
NMPABLHK_00036 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMPABLHK_00037 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
NMPABLHK_00038 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
NMPABLHK_00039 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
NMPABLHK_00040 1.4e-121 ktrA P COG0569 K transport systems, NAD-binding component
NMPABLHK_00041 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
NMPABLHK_00042 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NMPABLHK_00043 1.2e-149 cbiQ P cobalt transport
NMPABLHK_00044 0.0 ykoD P abc transporter atp-binding protein
NMPABLHK_00045 9.4e-95 S UPF0397 protein
NMPABLHK_00046 2.9e-159 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
NMPABLHK_00047 2.7e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NMPABLHK_00048 3e-98 metI P ABC transporter (Permease
NMPABLHK_00049 1.5e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMPABLHK_00050 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NMPABLHK_00051 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
NMPABLHK_00052 7.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
NMPABLHK_00053 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
NMPABLHK_00054 6.6e-119 ET amino acid transport
NMPABLHK_00055 1.9e-13
NMPABLHK_00056 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NMPABLHK_00057 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NMPABLHK_00058 6.6e-61 EGP Major facilitator Superfamily
NMPABLHK_00059 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
NMPABLHK_00060 1.3e-212 pqqE C radical SAM domain protein
NMPABLHK_00063 1.8e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
NMPABLHK_00064 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NMPABLHK_00065 3.9e-19 IQ Acetoin reductase
NMPABLHK_00066 1.8e-51 IQ Acetoin reductase
NMPABLHK_00067 2.7e-48 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMPABLHK_00068 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NMPABLHK_00069 1.1e-152 XK27_05470 E Methionine synthase
NMPABLHK_00070 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NMPABLHK_00071 1.3e-249 T PhoQ Sensor
NMPABLHK_00072 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMPABLHK_00073 3.6e-154 S TraX protein
NMPABLHK_00074 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMPABLHK_00075 8.3e-159 dprA LU DNA protecting protein DprA
NMPABLHK_00076 8.2e-168 GK ROK family
NMPABLHK_00077 5.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMPABLHK_00078 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMPABLHK_00079 9.6e-129 K DNA-binding helix-turn-helix protein
NMPABLHK_00080 6e-91 niaR S small molecule binding protein (contains 3H domain)
NMPABLHK_00081 2.4e-87 niaX
NMPABLHK_00082 5.9e-275 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMPABLHK_00083 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMPABLHK_00084 2e-126 gntR1 K transcriptional
NMPABLHK_00085 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NMPABLHK_00086 1.1e-19 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
NMPABLHK_00087 4.2e-113 adhP 1.1.1.1 C alcohol dehydrogenase
NMPABLHK_00088 8e-58 adhP 1.1.1.1 C alcohol dehydrogenase
NMPABLHK_00089 2.1e-07
NMPABLHK_00090 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMPABLHK_00091 1.1e-46 aatB ET ABC transporter substrate-binding protein
NMPABLHK_00092 6.7e-47 glnQ 3.6.3.21 E abc transporter atp-binding protein
NMPABLHK_00093 2.4e-105 artQ P ABC transporter (Permease
NMPABLHK_00094 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
NMPABLHK_00095 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NMPABLHK_00096 2.6e-166 cpsY K Transcriptional regulator
NMPABLHK_00097 3.2e-35 L transposase activity
NMPABLHK_00098 5.1e-117 mur1 NU muramidase
NMPABLHK_00099 1.2e-172 yeiH S Membrane
NMPABLHK_00101 1.7e-08
NMPABLHK_00102 9.2e-297 adcA P Belongs to the bacterial solute-binding protein 9 family
NMPABLHK_00103 2.2e-101 XK27_10720 D peptidase activity
NMPABLHK_00104 1.1e-278 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NMPABLHK_00105 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NMPABLHK_00106 0.0 dnaE 2.7.7.7 L DNA polymerase
NMPABLHK_00107 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
NMPABLHK_00108 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMPABLHK_00109 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMPABLHK_00110 2.5e-43 ysdA L Membrane
NMPABLHK_00111 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NMPABLHK_00112 3.4e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMPABLHK_00113 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NMPABLHK_00114 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
NMPABLHK_00116 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMPABLHK_00117 2.1e-84 ypmS S Protein conserved in bacteria
NMPABLHK_00118 1.3e-143 ypmR E lipolytic protein G-D-S-L family
NMPABLHK_00119 1e-148 DegV S DegV family
NMPABLHK_00120 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
NMPABLHK_00121 3.7e-73 argR K Regulates arginine biosynthesis genes
NMPABLHK_00122 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NMPABLHK_00123 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMPABLHK_00124 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
NMPABLHK_00125 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMPABLHK_00128 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMPABLHK_00129 2.9e-125 dnaD
NMPABLHK_00130 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMPABLHK_00131 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMPABLHK_00132 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
NMPABLHK_00133 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMPABLHK_00134 9.2e-175 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NMPABLHK_00135 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NMPABLHK_00136 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMPABLHK_00137 5.4e-197 L transposase, IS4 family
NMPABLHK_00138 5.6e-240 rodA D Belongs to the SEDS family
NMPABLHK_00139 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
NMPABLHK_00140 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NMPABLHK_00141 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NMPABLHK_00142 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NMPABLHK_00143 3.2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NMPABLHK_00144 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NMPABLHK_00145 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMPABLHK_00146 2.7e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NMPABLHK_00147 1.5e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NMPABLHK_00148 1.5e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMPABLHK_00150 6.6e-31 L Integrase core domain protein
NMPABLHK_00151 1.7e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMPABLHK_00152 3.5e-97 mip S hydroperoxide reductase activity
NMPABLHK_00153 2.4e-203 I acyl-CoA dehydrogenase
NMPABLHK_00154 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
NMPABLHK_00155 2.6e-253 msrR K Transcriptional regulator
NMPABLHK_00156 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
NMPABLHK_00157 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NMPABLHK_00158 2.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NMPABLHK_00159 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NMPABLHK_00160 3.2e-53 yheA S Belongs to the UPF0342 family
NMPABLHK_00161 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NMPABLHK_00162 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NMPABLHK_00163 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NMPABLHK_00164 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NMPABLHK_00165 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NMPABLHK_00166 6.9e-220 ywbD 2.1.1.191 J Methyltransferase
NMPABLHK_00167 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMPABLHK_00168 2e-25 WQ51_00785
NMPABLHK_00169 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMPABLHK_00170 1e-78 yueI S Protein of unknown function (DUF1694)
NMPABLHK_00171 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NMPABLHK_00172 6.6e-101 yyaQ V Protein conserved in bacteria
NMPABLHK_00173 2.8e-28 yyaQ S YjbR
NMPABLHK_00174 4.4e-183 ccpA K Catabolite control protein A
NMPABLHK_00175 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
NMPABLHK_00176 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
NMPABLHK_00177 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMPABLHK_00178 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NMPABLHK_00179 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NMPABLHK_00180 2.6e-33 secG U Preprotein translocase subunit SecG
NMPABLHK_00181 9.5e-74 mdtG EGP Major facilitator Superfamily
NMPABLHK_00182 6e-133 mdtG EGP Major facilitator Superfamily
NMPABLHK_00183 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMPABLHK_00184 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NMPABLHK_00185 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMPABLHK_00186 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NMPABLHK_00187 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMPABLHK_00188 6.8e-53 licT K transcriptional antiterminator
NMPABLHK_00189 9.2e-43 licT K transcriptional antiterminator
NMPABLHK_00191 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMPABLHK_00192 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
NMPABLHK_00193 3.2e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMPABLHK_00194 2.1e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMPABLHK_00195 7.5e-23 I Alpha/beta hydrolase family
NMPABLHK_00196 1.5e-35 yugF I carboxylic ester hydrolase activity
NMPABLHK_00197 2.2e-45 K sequence-specific DNA binding
NMPABLHK_00198 1.6e-24 U response to pH
NMPABLHK_00199 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
NMPABLHK_00200 2.1e-204 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
NMPABLHK_00201 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMPABLHK_00202 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NMPABLHK_00203 1.9e-77 K DNA-binding transcription factor activity
NMPABLHK_00204 0.0 lmrA1 V abc transporter atp-binding protein
NMPABLHK_00205 0.0 lmrA2 V abc transporter atp-binding protein
NMPABLHK_00206 1.6e-44 K Acetyltransferase (GNAT) family
NMPABLHK_00207 2.9e-120 sptS 2.7.13.3 T Histidine kinase
NMPABLHK_00208 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NMPABLHK_00209 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NMPABLHK_00210 5.3e-161 cvfB S Protein conserved in bacteria
NMPABLHK_00211 7.4e-35 yozE S Belongs to the UPF0346 family
NMPABLHK_00212 8.2e-130 usp 3.5.1.104, 3.5.1.28 CBM50 S pathogenesis
NMPABLHK_00213 2.3e-61 rlpA M LysM domain protein
NMPABLHK_00214 8e-191 phoH T phosphate starvation-inducible protein PhoH
NMPABLHK_00218 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMPABLHK_00219 1.8e-167 K transcriptional regulator (lysR family)
NMPABLHK_00220 1.4e-186 coiA 3.6.4.12 S Competence protein
NMPABLHK_00221 0.0 pepF E oligoendopeptidase F
NMPABLHK_00222 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
NMPABLHK_00223 4.6e-168 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
NMPABLHK_00224 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMPABLHK_00225 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NMPABLHK_00226 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NMPABLHK_00227 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
NMPABLHK_00228 7.1e-89 3.4.17.14, 3.5.1.28 NU amidase activity
NMPABLHK_00229 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMPABLHK_00230 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
NMPABLHK_00231 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NMPABLHK_00232 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NMPABLHK_00233 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NMPABLHK_00234 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NMPABLHK_00235 8.5e-142 yxkH G deacetylase
NMPABLHK_00236 4.8e-196 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
NMPABLHK_00237 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NMPABLHK_00238 3.2e-92 dps P Belongs to the Dps family
NMPABLHK_00239 1.1e-80 perR P Belongs to the Fur family
NMPABLHK_00240 8.4e-28 yqgQ S protein conserved in bacteria
NMPABLHK_00241 2.2e-179 glk 2.7.1.2 G Glucokinase
NMPABLHK_00242 0.0 typA T GTP-binding protein TypA
NMPABLHK_00244 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMPABLHK_00245 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMPABLHK_00246 6.7e-172 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NMPABLHK_00247 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NMPABLHK_00248 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMPABLHK_00249 2.7e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMPABLHK_00250 1.4e-96 sepF D cell septum assembly
NMPABLHK_00251 2e-34 yggT D integral membrane protein
NMPABLHK_00252 4.2e-144 ylmH T S4 RNA-binding domain
NMPABLHK_00253 1.8e-135 divIVA D Cell division protein DivIVA
NMPABLHK_00254 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMPABLHK_00255 1.3e-10
NMPABLHK_00256 3.2e-231 mntH P Mn2 and Fe2 transporters of the NRAMP family
NMPABLHK_00257 2e-45 rpmE2 J 50S ribosomal protein L31
NMPABLHK_00258 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NMPABLHK_00259 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
NMPABLHK_00260 2.4e-155 gst O Glutathione S-transferase
NMPABLHK_00261 1.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NMPABLHK_00262 4.5e-111 tdk 2.7.1.21 F thymidine kinase
NMPABLHK_00263 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMPABLHK_00264 1.2e-154 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NMPABLHK_00265 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NMPABLHK_00266 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMPABLHK_00267 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
NMPABLHK_00268 7.2e-101 pvaA M lytic transglycosylase activity
NMPABLHK_00269 0.0 yfiB1 V abc transporter atp-binding protein
NMPABLHK_00270 0.0 XK27_10035 V abc transporter atp-binding protein
NMPABLHK_00271 1.6e-09 S D-Ala-teichoic acid biosynthesis protein
NMPABLHK_00272 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMPABLHK_00273 4.6e-238 dltB M Membrane protein involved in D-alanine export
NMPABLHK_00274 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMPABLHK_00275 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMPABLHK_00276 4.6e-55 L Integrase core domain protein
NMPABLHK_00277 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMPABLHK_00278 3.5e-143 pts33BCA G pts system
NMPABLHK_00279 5.8e-71 pts33BCA G pts system
NMPABLHK_00280 2.4e-09 uvrX 2.7.7.7 L impB/mucB/samB family
NMPABLHK_00281 1.8e-254 cycA E permease
NMPABLHK_00282 4.5e-39 ynzC S UPF0291 protein
NMPABLHK_00283 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NMPABLHK_00284 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NMPABLHK_00285 6.1e-63 S membrane
NMPABLHK_00286 1.5e-59
NMPABLHK_00287 7.5e-26
NMPABLHK_00288 1.8e-53
NMPABLHK_00289 1.9e-222 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMPABLHK_00290 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
NMPABLHK_00291 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
NMPABLHK_00292 4.9e-106 mur1 NU mannosyl-glycoprotein
NMPABLHK_00293 1.1e-53 glnB K Belongs to the P(II) protein family
NMPABLHK_00294 2.6e-233 amt P Ammonium Transporter
NMPABLHK_00295 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMPABLHK_00296 9.5e-55 yabA L Involved in initiation control of chromosome replication
NMPABLHK_00297 1.2e-135 yaaT S stage 0 sporulation protein
NMPABLHK_00298 6.4e-162 holB 2.7.7.7 L dna polymerase iii
NMPABLHK_00299 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMPABLHK_00300 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMPABLHK_00301 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMPABLHK_00302 2.8e-230 ftsW D Belongs to the SEDS family
NMPABLHK_00303 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NMPABLHK_00304 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMPABLHK_00305 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMPABLHK_00306 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMPABLHK_00307 9.3e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMPABLHK_00308 3.3e-78 atpF C ATP synthase F(0) sector subunit b
NMPABLHK_00309 4.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
NMPABLHK_00310 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMPABLHK_00311 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NMPABLHK_00312 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NMPABLHK_00313 6.6e-147 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NMPABLHK_00314 8.9e-14 coiA 3.6.4.12 S Competence protein
NMPABLHK_00315 2.2e-15 T peptidase
NMPABLHK_00316 5.5e-153 rarD S Transporter
NMPABLHK_00317 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NMPABLHK_00318 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NMPABLHK_00319 3.2e-153 ycdO P periplasmic lipoprotein involved in iron transport
NMPABLHK_00320 8.7e-234 ycdB P peroxidase
NMPABLHK_00321 7.2e-303 ywbL P COG0672 High-affinity Fe2 Pb2 permease
NMPABLHK_00322 9e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMPABLHK_00323 4.6e-25 tatA U protein secretion
NMPABLHK_00324 2.3e-23 L Transposase
NMPABLHK_00325 1.2e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
NMPABLHK_00326 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NMPABLHK_00329 2.9e-187 lplA 6.3.1.20 H Lipoate-protein ligase
NMPABLHK_00330 8.3e-196 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
NMPABLHK_00331 0.0 pepN 3.4.11.2 E aminopeptidase
NMPABLHK_00332 1.9e-113 phoU P Plays a role in the regulation of phosphate uptake
NMPABLHK_00333 2.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMPABLHK_00334 1e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMPABLHK_00335 1.2e-155 pstA P phosphate transport system permease
NMPABLHK_00336 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
NMPABLHK_00337 3.3e-158 pstS P phosphate
NMPABLHK_00338 7.9e-257 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NMPABLHK_00339 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NMPABLHK_00340 1.9e-43 yktA S Belongs to the UPF0223 family
NMPABLHK_00341 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NMPABLHK_00342 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NMPABLHK_00343 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMPABLHK_00344 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
NMPABLHK_00345 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
NMPABLHK_00346 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
NMPABLHK_00347 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMPABLHK_00348 9.3e-62 S haloacid dehalogenase-like hydrolase
NMPABLHK_00349 1.8e-59 Q phosphatase activity
NMPABLHK_00350 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
NMPABLHK_00351 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NMPABLHK_00352 1.8e-240 agcS E (Alanine) symporter
NMPABLHK_00353 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMPABLHK_00354 4e-99 yfiF3 K sequence-specific DNA binding
NMPABLHK_00355 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
NMPABLHK_00356 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMPABLHK_00357 4.4e-123 comFC S Competence protein
NMPABLHK_00358 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NMPABLHK_00359 6.3e-111 yvyE 3.4.13.9 S YigZ family
NMPABLHK_00360 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMPABLHK_00361 3.3e-43 acuB S IMP dehydrogenase activity
NMPABLHK_00362 1.1e-69 acuB S IMP dehydrogenase activity
NMPABLHK_00363 9.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
NMPABLHK_00364 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
NMPABLHK_00365 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
NMPABLHK_00366 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
NMPABLHK_00367 1.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
NMPABLHK_00368 7.1e-46 ylbG S UPF0298 protein
NMPABLHK_00369 3.4e-74 ylbF S Belongs to the UPF0342 family
NMPABLHK_00370 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NMPABLHK_00371 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMPABLHK_00372 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
NMPABLHK_00374 1e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NMPABLHK_00375 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
NMPABLHK_00376 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
NMPABLHK_00377 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
NMPABLHK_00378 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMPABLHK_00379 3.2e-214 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
NMPABLHK_00380 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
NMPABLHK_00381 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
NMPABLHK_00382 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMPABLHK_00383 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMPABLHK_00384 1.4e-41 ylxQ J ribosomal protein
NMPABLHK_00385 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
NMPABLHK_00386 3.1e-212 nusA K Participates in both transcription termination and antitermination
NMPABLHK_00387 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
NMPABLHK_00388 2.5e-220 brpA K Transcriptional
NMPABLHK_00389 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
NMPABLHK_00390 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
NMPABLHK_00391 1.9e-248 pbuO S permease
NMPABLHK_00392 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NMPABLHK_00393 1.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
NMPABLHK_00394 1.3e-174 manL 2.7.1.191 G pts system
NMPABLHK_00395 7e-118 manM G pts system
NMPABLHK_00396 1.9e-169 manN G PTS system mannose fructose sorbose family IID component
NMPABLHK_00397 6.5e-63 manO S protein conserved in bacteria
NMPABLHK_00398 1.5e-231 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMPABLHK_00399 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMPABLHK_00400 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMPABLHK_00401 2.7e-17 oppA E ABC transporter substrate-binding protein
NMPABLHK_00402 5.4e-99 oppA E ABC transporter substrate-binding protein
NMPABLHK_00403 2.4e-19 oppA E ABC transporter substrate-binding protein
NMPABLHK_00404 3.5e-274 sufB O assembly protein SufB
NMPABLHK_00405 1.1e-74 nifU C SUF system FeS assembly protein, NifU family
NMPABLHK_00406 2.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMPABLHK_00407 6.3e-235 sufD O assembly protein SufD
NMPABLHK_00408 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NMPABLHK_00409 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
NMPABLHK_00410 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NMPABLHK_00411 9.1e-153 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NMPABLHK_00412 1.8e-276 glnP P ABC transporter
NMPABLHK_00413 1e-123 glnQ E abc transporter atp-binding protein
NMPABLHK_00416 5e-94 V VanZ like family
NMPABLHK_00417 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMPABLHK_00418 6.5e-202 yhjX P Major Facilitator
NMPABLHK_00419 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
NMPABLHK_00420 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMPABLHK_00421 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NMPABLHK_00422 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NMPABLHK_00423 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NMPABLHK_00424 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NMPABLHK_00425 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NMPABLHK_00426 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NMPABLHK_00427 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMPABLHK_00428 2.4e-83 nrdI F Belongs to the NrdI family
NMPABLHK_00429 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NMPABLHK_00430 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NMPABLHK_00431 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
NMPABLHK_00432 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
NMPABLHK_00433 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
NMPABLHK_00434 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NMPABLHK_00435 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NMPABLHK_00436 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NMPABLHK_00437 3e-148 ykuT M mechanosensitive ion channel
NMPABLHK_00438 1.6e-77 sigH K DNA-templated transcription, initiation
NMPABLHK_00439 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
NMPABLHK_00440 6.9e-206 ylbM S Belongs to the UPF0348 family
NMPABLHK_00441 2e-140 yqeM Q Methyltransferase domain protein
NMPABLHK_00442 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NMPABLHK_00443 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NMPABLHK_00444 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMPABLHK_00445 3.5e-49 yhbY J RNA-binding protein
NMPABLHK_00446 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NMPABLHK_00447 1.8e-98 yqeG S hydrolase of the HAD superfamily
NMPABLHK_00448 1.1e-153 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMPABLHK_00449 5.8e-24
NMPABLHK_00450 3.5e-13
NMPABLHK_00451 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMPABLHK_00452 2.4e-270 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NMPABLHK_00453 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMPABLHK_00454 1.3e-251 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMPABLHK_00455 6.7e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMPABLHK_00456 1.6e-154 hlpA M Belongs to the NlpA lipoprotein family
NMPABLHK_00457 6.8e-101 pncA Q isochorismatase
NMPABLHK_00458 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NMPABLHK_00459 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
NMPABLHK_00460 2.4e-75 XK27_03180 T universal stress protein
NMPABLHK_00463 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NMPABLHK_00464 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
NMPABLHK_00465 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
NMPABLHK_00466 0.0 yjcE P NhaP-type Na H and K H antiporters
NMPABLHK_00468 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
NMPABLHK_00469 1.3e-184 yhcC S radical SAM protein
NMPABLHK_00470 2.2e-196 ylbL T Belongs to the peptidase S16 family
NMPABLHK_00471 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NMPABLHK_00472 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
NMPABLHK_00473 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMPABLHK_00474 1.9e-09 S Protein of unknown function (DUF4059)
NMPABLHK_00475 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
NMPABLHK_00476 4.7e-163 yxeN P ABC transporter (Permease
NMPABLHK_00477 1.2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NMPABLHK_00479 1.4e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMPABLHK_00480 0.0 pflB 2.3.1.54 C formate acetyltransferase'
NMPABLHK_00481 1.8e-147 cah 4.2.1.1 P carbonic anhydrase
NMPABLHK_00482 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMPABLHK_00483 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
NMPABLHK_00484 2.9e-87 D nuclear chromosome segregation
NMPABLHK_00485 1.5e-127 ybbM S transport system, permease component
NMPABLHK_00486 1.2e-117 ybbL S abc transporter atp-binding protein
NMPABLHK_00487 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
NMPABLHK_00488 4.6e-140 cppA E CppA N-terminal
NMPABLHK_00489 5e-44 V CAAX protease self-immunity
NMPABLHK_00490 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
NMPABLHK_00491 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NMPABLHK_00494 3e-47 spiA K sequence-specific DNA binding
NMPABLHK_00495 2.9e-28 blpT
NMPABLHK_00496 6.7e-98 blpT
NMPABLHK_00503 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
NMPABLHK_00507 7.4e-135 agrA KT phosphorelay signal transduction system
NMPABLHK_00508 3.4e-239 blpH 2.7.13.3 T protein histidine kinase activity
NMPABLHK_00510 7.3e-237 mesE M Transport protein ComB
NMPABLHK_00511 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NMPABLHK_00512 0.0 mdlB V abc transporter atp-binding protein
NMPABLHK_00513 9.1e-303 mdlA V abc transporter atp-binding protein
NMPABLHK_00515 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
NMPABLHK_00516 7.9e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NMPABLHK_00517 3.6e-70 yutD J protein conserved in bacteria
NMPABLHK_00518 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NMPABLHK_00520 1.4e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NMPABLHK_00521 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMPABLHK_00522 0.0 ftsI 3.4.16.4 M penicillin-binding protein
NMPABLHK_00523 4.3e-47 ftsL D cell division protein FtsL
NMPABLHK_00524 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NMPABLHK_00525 1.6e-65
NMPABLHK_00526 7.4e-27
NMPABLHK_00527 2.6e-30
NMPABLHK_00529 9.7e-32 yhaI J Protein of unknown function (DUF805)
NMPABLHK_00530 1.3e-08 D nuclear chromosome segregation
NMPABLHK_00531 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMPABLHK_00532 4.4e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMPABLHK_00533 6.2e-288 XK27_00765
NMPABLHK_00534 1.4e-133 ecsA_2 V abc transporter atp-binding protein
NMPABLHK_00535 2.5e-47 S Protein of unknown function (DUF554)
NMPABLHK_00536 8.5e-32 S Protein of unknown function (DUF554)
NMPABLHK_00537 1.6e-11 S Protein of unknown function (DUF554)
NMPABLHK_00538 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NMPABLHK_00539 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NMPABLHK_00540 2.6e-121 liaI S membrane
NMPABLHK_00541 5.2e-75 XK27_02470 K LytTr DNA-binding domain
NMPABLHK_00542 3.6e-66 KT response to antibiotic
NMPABLHK_00543 2.6e-80 yebC M Membrane
NMPABLHK_00544 2.9e-18 yebC M Membrane
NMPABLHK_00545 4.3e-261 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
NMPABLHK_00546 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NMPABLHK_00550 4.7e-43
NMPABLHK_00551 6.8e-56 S TM2 domain
NMPABLHK_00552 7.3e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMPABLHK_00553 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMPABLHK_00554 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
NMPABLHK_00555 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
NMPABLHK_00556 9.3e-86 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
NMPABLHK_00557 6e-55 cof Q phosphatase activity
NMPABLHK_00558 4e-34 cof Q phosphatase activity
NMPABLHK_00559 2.8e-76 glcR K transcriptional regulator (DeoR family)
NMPABLHK_00560 3.9e-21 glcR K transcriptional regulator (DeoR family)
NMPABLHK_00561 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMPABLHK_00562 3.8e-40 K transcriptional
NMPABLHK_00564 2.6e-76 S thiolester hydrolase activity
NMPABLHK_00565 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
NMPABLHK_00566 5.7e-280 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMPABLHK_00567 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NMPABLHK_00568 1.9e-77 yhaI L Membrane
NMPABLHK_00569 4.6e-260 pepC 3.4.22.40 E aminopeptidase
NMPABLHK_00570 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMPABLHK_00571 2.5e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMPABLHK_00572 3.1e-95 ypsA S Belongs to the UPF0398 family
NMPABLHK_00573 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NMPABLHK_00574 7.9e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NMPABLHK_00575 1e-305 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
NMPABLHK_00576 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
NMPABLHK_00577 2.5e-23
NMPABLHK_00578 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NMPABLHK_00579 3.1e-20 XK27_09675 K -acetyltransferase
NMPABLHK_00580 9.3e-46 XK27_09675 K -acetyltransferase
NMPABLHK_00581 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMPABLHK_00582 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMPABLHK_00583 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMPABLHK_00584 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NMPABLHK_00585 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMPABLHK_00586 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
NMPABLHK_00587 1.5e-97 ybhL S Belongs to the BI1 family
NMPABLHK_00590 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NMPABLHK_00591 9.6e-92 K transcriptional regulator
NMPABLHK_00592 7.6e-36 yneF S UPF0154 protein
NMPABLHK_00593 1.3e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMPABLHK_00594 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMPABLHK_00595 3.5e-99 XK27_09740 S Phosphoesterase
NMPABLHK_00596 5.4e-86 ykuL S CBS domain
NMPABLHK_00597 3.3e-138 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
NMPABLHK_00598 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMPABLHK_00599 2.3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMPABLHK_00600 1.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMPABLHK_00601 1.2e-258 trkH P Cation transport protein
NMPABLHK_00602 1.8e-248 trkA P Potassium transporter peripheral membrane component
NMPABLHK_00603 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NMPABLHK_00604 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMPABLHK_00605 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
NMPABLHK_00606 2.5e-161 K sequence-specific DNA binding
NMPABLHK_00607 1.6e-32 V protein secretion by the type I secretion system
NMPABLHK_00608 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NMPABLHK_00609 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NMPABLHK_00610 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NMPABLHK_00611 3.7e-22 yhaI L Membrane
NMPABLHK_00612 1.4e-54 S Domain of unknown function (DUF4173)
NMPABLHK_00613 6.8e-95 ureI S AmiS/UreI family transporter
NMPABLHK_00614 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NMPABLHK_00615 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NMPABLHK_00616 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NMPABLHK_00617 6.6e-78 ureE O enzyme active site formation
NMPABLHK_00618 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NMPABLHK_00619 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NMPABLHK_00620 8.9e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NMPABLHK_00621 2.7e-177 cbiM P PDGLE domain
NMPABLHK_00622 1.7e-137 P cobalt transport protein
NMPABLHK_00623 1.6e-131 cbiO P ABC transporter
NMPABLHK_00624 5.8e-62 L PFAM Integrase, catalytic core
NMPABLHK_00625 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
NMPABLHK_00627 6.7e-110 6.3.2.2 H ergothioneine biosynthetic process
NMPABLHK_00628 9.6e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
NMPABLHK_00629 7.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
NMPABLHK_00630 3.3e-09 L PFAM Integrase, catalytic core
NMPABLHK_00631 1.8e-111 L PFAM Integrase, catalytic core
NMPABLHK_00632 3.3e-62 rplQ J ribosomal protein l17
NMPABLHK_00633 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMPABLHK_00634 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMPABLHK_00635 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMPABLHK_00636 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NMPABLHK_00637 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMPABLHK_00638 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NMPABLHK_00639 2.3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NMPABLHK_00640 4.4e-58 rplO J binds to the 23S rRNA
NMPABLHK_00641 2.5e-23 rpmD J ribosomal protein l30
NMPABLHK_00642 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMPABLHK_00643 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMPABLHK_00644 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMPABLHK_00645 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMPABLHK_00646 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMPABLHK_00647 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMPABLHK_00648 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMPABLHK_00649 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMPABLHK_00650 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMPABLHK_00651 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
NMPABLHK_00652 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMPABLHK_00653 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMPABLHK_00654 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMPABLHK_00655 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMPABLHK_00656 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMPABLHK_00657 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NMPABLHK_00658 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
NMPABLHK_00659 1.1e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMPABLHK_00660 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
NMPABLHK_00661 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NMPABLHK_00662 0.0 XK27_09800 I Acyltransferase
NMPABLHK_00663 1.7e-35 XK27_09805 S MORN repeat protein
NMPABLHK_00664 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMPABLHK_00665 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMPABLHK_00666 8.8e-83 adk 2.7.4.3 F topology modulation protein
NMPABLHK_00667 3.1e-172 yxaM EGP Major facilitator Superfamily
NMPABLHK_00668 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
NMPABLHK_00669 6.4e-18 L transposase activity
NMPABLHK_00670 4.4e-37 L Transposase
NMPABLHK_00671 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMPABLHK_00672 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMPABLHK_00673 5.2e-142 cmpC S abc transporter atp-binding protein
NMPABLHK_00674 0.0 WQ51_06230 S ABC transporter substrate binding protein
NMPABLHK_00675 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NMPABLHK_00676 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NMPABLHK_00677 1.3e-145 cdsA 2.7.7.41 S Belongs to the CDS family
NMPABLHK_00678 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMPABLHK_00679 9.8e-50 yajC U protein transport
NMPABLHK_00680 1.9e-127 yeeN K transcriptional regulatory protein
NMPABLHK_00681 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
NMPABLHK_00682 1e-150 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
NMPABLHK_00683 1.7e-82 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NMPABLHK_00684 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
NMPABLHK_00685 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
NMPABLHK_00686 4.8e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NMPABLHK_00687 5.4e-131 adcB P ABC transporter (Permease
NMPABLHK_00688 2.2e-136 adcC P ABC transporter, ATP-binding protein
NMPABLHK_00689 3.1e-72 adcR K transcriptional
NMPABLHK_00690 1.9e-209 EGP Major facilitator Superfamily
NMPABLHK_00691 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMPABLHK_00692 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMPABLHK_00695 9e-170 oppF P Belongs to the ABC transporter superfamily
NMPABLHK_00696 1.3e-44 oppD P Belongs to the ABC transporter superfamily
NMPABLHK_00697 4.8e-67 oppD P Belongs to the ABC transporter superfamily
NMPABLHK_00698 2.5e-32 oppD P Belongs to the ABC transporter superfamily
NMPABLHK_00699 8e-28 oppD P Belongs to the ABC transporter superfamily
NMPABLHK_00700 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMPABLHK_00701 1.1e-202 rny D Endoribonuclease that initiates mRNA decay
NMPABLHK_00702 1.8e-84 L Transposase
NMPABLHK_00703 5.6e-114 fruR K transcriptional
NMPABLHK_00704 2.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NMPABLHK_00705 8e-98 fruA 2.7.1.202 G phosphotransferase system
NMPABLHK_00706 5.1e-145 fruA 2.7.1.202 G phosphotransferase system
NMPABLHK_00707 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
NMPABLHK_00708 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMPABLHK_00709 2.4e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NMPABLHK_00711 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
NMPABLHK_00712 2.9e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMPABLHK_00713 2.2e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NMPABLHK_00714 7.2e-258 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NMPABLHK_00715 6.4e-29 2.3.1.128 K acetyltransferase
NMPABLHK_00716 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NMPABLHK_00717 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NMPABLHK_00718 7.7e-134 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NMPABLHK_00719 2.6e-64 WQ51_03320 S cog cog4835
NMPABLHK_00720 6.4e-61 XK27_08360 S EDD domain protein, DegV family
NMPABLHK_00721 3.6e-74 XK27_08360 S EDD domain protein, DegV family
NMPABLHK_00722 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NMPABLHK_00723 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NMPABLHK_00724 0.0 yfmR S abc transporter atp-binding protein
NMPABLHK_00725 1.2e-101 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMPABLHK_00726 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMPABLHK_00727 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMPABLHK_00728 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
NMPABLHK_00729 4.8e-16 S Protein of unknown function (DUF2969)
NMPABLHK_00732 6.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
NMPABLHK_00735 1e-29 S Domain of Unknown Function with PDB structure (DUF3862)
NMPABLHK_00736 1.5e-30 S Domain of Unknown Function with PDB structure (DUF3862)
NMPABLHK_00737 1.7e-63 M Pfam SNARE associated Golgi protein
NMPABLHK_00738 6.8e-234 murN 2.3.2.10, 2.3.2.16 V FemAB family
NMPABLHK_00739 1.5e-50 S oxidoreductase
NMPABLHK_00740 2.4e-66 S oxidoreductase
NMPABLHK_00741 7.4e-49 XK27_09445 S Domain of unknown function (DUF1827)
NMPABLHK_00742 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NMPABLHK_00743 0.0 clpE O Belongs to the ClpA ClpB family
NMPABLHK_00744 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMPABLHK_00745 1.3e-34 ykuJ S protein conserved in bacteria
NMPABLHK_00746 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
NMPABLHK_00747 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
NMPABLHK_00748 1.1e-78 feoA P FeoA domain protein
NMPABLHK_00749 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NMPABLHK_00750 1.5e-07
NMPABLHK_00751 1.5e-25 estA E GDSL-like Lipase/Acylhydrolase
NMPABLHK_00752 4.4e-93
NMPABLHK_00753 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NMPABLHK_00754 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NMPABLHK_00755 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NMPABLHK_00756 2.3e-198 S CRISPR-associated protein Csn2 subfamily St
NMPABLHK_00757 1.3e-148 ycgQ S TIGR03943 family
NMPABLHK_00758 1.7e-157 XK27_03015 S permease
NMPABLHK_00760 0.0 yhgF K Transcriptional accessory protein
NMPABLHK_00761 9.9e-42 pspC KT PspC domain
NMPABLHK_00762 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMPABLHK_00763 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMPABLHK_00765 5.5e-69 ytxH S General stress protein
NMPABLHK_00767 4.4e-177 yegQ O Peptidase U32
NMPABLHK_00768 3.4e-252 yegQ O Peptidase U32
NMPABLHK_00769 1.5e-89 bioY S biotin synthase
NMPABLHK_00771 1.1e-33 XK27_12190 S protein conserved in bacteria
NMPABLHK_00772 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
NMPABLHK_00773 1.9e-12
NMPABLHK_00774 1.4e-20 L transposase activity
NMPABLHK_00775 3.5e-50 L transposition
NMPABLHK_00776 2e-32 L Integrase core domain protein
NMPABLHK_00777 2.3e-161 S CHAP domain
NMPABLHK_00778 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
NMPABLHK_00779 3.8e-70 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NMPABLHK_00780 2.2e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NMPABLHK_00781 9.2e-141 1.1.1.169 H Ketopantoate reductase
NMPABLHK_00782 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMPABLHK_00783 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NMPABLHK_00784 8.2e-70 argR K Regulates arginine biosynthesis genes
NMPABLHK_00785 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NMPABLHK_00786 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMPABLHK_00787 1.9e-80 S Protein of unknown function (DUF3021)
NMPABLHK_00788 6.5e-63 KT phosphorelay signal transduction system
NMPABLHK_00790 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMPABLHK_00792 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NMPABLHK_00793 6.4e-107 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
NMPABLHK_00794 1e-232 cinA 3.5.1.42 S Belongs to the CinA family
NMPABLHK_00795 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMPABLHK_00796 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
NMPABLHK_00797 5.8e-135 macB2 V ABC transporter, ATP-binding protein
NMPABLHK_00798 6.2e-166 T Histidine kinase
NMPABLHK_00799 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMPABLHK_00800 5.4e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NMPABLHK_00802 3.3e-69 pbuX F xanthine permease
NMPABLHK_00803 9.2e-119 pbuX F xanthine permease
NMPABLHK_00804 5.3e-248 norM V Multidrug efflux pump
NMPABLHK_00805 4.3e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMPABLHK_00806 7.8e-236 brnQ E Component of the transport system for branched-chain amino acids
NMPABLHK_00807 2.9e-66 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMPABLHK_00808 2.8e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMPABLHK_00809 9.6e-26 csbD K CsbD-like
NMPABLHK_00810 1.5e-245 yfnA E amino acid
NMPABLHK_00811 6.1e-111 XK27_02070 S nitroreductase
NMPABLHK_00812 2.1e-154 1.13.11.2 S glyoxalase
NMPABLHK_00813 3.3e-77 ywnA K Transcriptional regulator
NMPABLHK_00814 6.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
NMPABLHK_00815 2.4e-234 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMPABLHK_00816 1.3e-111 drgA C Nitroreductase
NMPABLHK_00817 2.4e-75 yoaK S Protein of unknown function (DUF1275)
NMPABLHK_00818 3.1e-161 yvgN C reductase
NMPABLHK_00819 5.6e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NMPABLHK_00820 2.4e-09
NMPABLHK_00823 7e-27 Q the current gene model (or a revised gene model) may contain a frame shift
NMPABLHK_00824 1.1e-43 Q the current gene model (or a revised gene model) may contain a frame shift
NMPABLHK_00826 3.2e-17 S Domain of unknown function (DUF4649)
NMPABLHK_00827 3.3e-178 XK27_08835 S ABC transporter substrate binding protein
NMPABLHK_00828 4e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
NMPABLHK_00829 1.2e-135 XK27_08845 S abc transporter atp-binding protein
NMPABLHK_00830 3.5e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMPABLHK_00831 9.2e-152 estA CE1 S Putative esterase
NMPABLHK_00832 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
NMPABLHK_00833 5.5e-14 XK27_08880
NMPABLHK_00834 2.3e-75 fld C Flavodoxin
NMPABLHK_00835 6.4e-282 clcA P Chloride transporter, ClC family
NMPABLHK_00836 5.1e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
NMPABLHK_00837 3.2e-220 XK27_05110 P chloride
NMPABLHK_00838 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NMPABLHK_00841 2.1e-19 WQ51_02665 S Protein of unknown function (DUF3042)
NMPABLHK_00842 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMPABLHK_00843 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NMPABLHK_00844 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMPABLHK_00845 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NMPABLHK_00846 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMPABLHK_00847 1.7e-173 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
NMPABLHK_00848 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
NMPABLHK_00849 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NMPABLHK_00850 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NMPABLHK_00851 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NMPABLHK_00852 1.1e-136 gltS ET Belongs to the bacterial solute-binding protein 3 family
NMPABLHK_00853 1.6e-202 arcT 2.6.1.1 E Aminotransferase
NMPABLHK_00854 6.5e-137 ET ABC transporter
NMPABLHK_00855 7.5e-144 ET Belongs to the bacterial solute-binding protein 3 family
NMPABLHK_00856 2.9e-84 mutT 3.6.1.55 F Nudix family
NMPABLHK_00857 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NMPABLHK_00858 2.5e-56 V CAAX protease self-immunity
NMPABLHK_00859 2.4e-33 S CAAX amino terminal protease family protein
NMPABLHK_00860 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
NMPABLHK_00861 6e-137 glnQ 3.6.3.21 E abc transporter atp-binding protein
NMPABLHK_00862 1.1e-16 XK27_00735
NMPABLHK_00863 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMPABLHK_00865 2.1e-134 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMPABLHK_00868 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
NMPABLHK_00869 4.7e-51 ycaO O OsmC-like protein
NMPABLHK_00870 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
NMPABLHK_00872 1.6e-112 csn2 S CRISPR-associated protein (Cas_Csn2)
NMPABLHK_00873 2.6e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NMPABLHK_00874 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NMPABLHK_00875 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NMPABLHK_00876 6.7e-116 serB 3.1.3.3 E phosphoserine phosphatase
NMPABLHK_00877 3.2e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMPABLHK_00878 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMPABLHK_00879 2.6e-109 3.1.3.18 S IA, variant 1
NMPABLHK_00880 2.2e-117 lrgB M effector of murein hydrolase
NMPABLHK_00881 7.7e-56 lrgA S Effector of murein hydrolase LrgA
NMPABLHK_00883 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
NMPABLHK_00884 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
NMPABLHK_00885 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMPABLHK_00886 3.9e-104 wecD M Acetyltransferase GNAT family
NMPABLHK_00887 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NMPABLHK_00888 4.6e-58 GK ROK family
NMPABLHK_00889 2.1e-25 GK ROK family
NMPABLHK_00890 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
NMPABLHK_00891 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
NMPABLHK_00892 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
NMPABLHK_00893 2.3e-206 potD P spermidine putrescine ABC transporter
NMPABLHK_00894 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
NMPABLHK_00895 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
NMPABLHK_00896 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NMPABLHK_00897 7.8e-171 murB 1.3.1.98 M cell wall formation
NMPABLHK_00898 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMPABLHK_00899 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMPABLHK_00900 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
NMPABLHK_00901 1.2e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NMPABLHK_00902 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
NMPABLHK_00903 0.0 ydaO E amino acid
NMPABLHK_00904 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NMPABLHK_00905 4.1e-37 ylqC L Belongs to the UPF0109 family
NMPABLHK_00906 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NMPABLHK_00907 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
NMPABLHK_00908 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
NMPABLHK_00909 2.1e-74 S QueT transporter
NMPABLHK_00910 2.5e-08 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
NMPABLHK_00911 1.1e-89 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
NMPABLHK_00912 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMPABLHK_00913 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMPABLHK_00914 2.2e-85 ccl S cog cog4708
NMPABLHK_00915 5.8e-161 rbn E Belongs to the UPF0761 family
NMPABLHK_00916 1.9e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
NMPABLHK_00917 3e-232 ytoI K transcriptional regulator containing CBS domains
NMPABLHK_00918 1.1e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
NMPABLHK_00919 1.5e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMPABLHK_00920 0.0 comEC S Competence protein ComEC
NMPABLHK_00921 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
NMPABLHK_00922 1.7e-142 plsC 2.3.1.51 I Acyltransferase
NMPABLHK_00923 1.8e-140 nodB3 G deacetylase
NMPABLHK_00924 7.1e-141 yabB 2.1.1.223 L Methyltransferase
NMPABLHK_00925 1e-41 yazA L endonuclease containing a URI domain
NMPABLHK_00926 2.4e-239 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NMPABLHK_00927 2.3e-154 corA P CorA-like protein
NMPABLHK_00928 1.9e-62 yjqA S Bacterial PH domain
NMPABLHK_00929 2.3e-99 thiT S Thiamine transporter
NMPABLHK_00930 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NMPABLHK_00931 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NMPABLHK_00932 4.1e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NMPABLHK_00933 7.5e-258 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NMPABLHK_00934 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NMPABLHK_00935 7e-57 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NMPABLHK_00936 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMPABLHK_00937 1.6e-126 IQ reductase
NMPABLHK_00938 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NMPABLHK_00939 6.8e-173 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
NMPABLHK_00940 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMPABLHK_00941 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMPABLHK_00942 4e-72 marR K Transcriptional regulator, MarR family
NMPABLHK_00943 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
NMPABLHK_00944 1.9e-115 S Haloacid dehalogenase-like hydrolase
NMPABLHK_00945 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
NMPABLHK_00946 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
NMPABLHK_00947 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMPABLHK_00948 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
NMPABLHK_00949 1.3e-101 ygaC J Belongs to the UPF0374 family
NMPABLHK_00950 6.4e-108 S Domain of unknown function (DUF1803)
NMPABLHK_00951 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
NMPABLHK_00964 5.3e-11
NMPABLHK_00970 1.3e-140 mreC M Involved in formation and maintenance of cell shape
NMPABLHK_00971 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NMPABLHK_00972 8.9e-102 usp 3.5.1.28 CBM50 S CHAP domain
NMPABLHK_00973 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMPABLHK_00974 2.5e-26
NMPABLHK_00975 5.9e-219 araT 2.6.1.1 E Aminotransferase
NMPABLHK_00976 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
NMPABLHK_00977 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NMPABLHK_00978 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMPABLHK_00979 5.2e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NMPABLHK_00980 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMPABLHK_00981 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NMPABLHK_00982 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NMPABLHK_00983 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMPABLHK_00984 6.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NMPABLHK_00985 5.8e-79 T PhoQ Sensor
NMPABLHK_00986 1.7e-43 T PhoQ Sensor
NMPABLHK_00987 2.8e-40 T PhoQ Sensor
NMPABLHK_00988 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMPABLHK_00989 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NMPABLHK_00990 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
NMPABLHK_00991 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMPABLHK_00992 1.7e-94 panT S ECF transporter, substrate-specific component
NMPABLHK_00993 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NMPABLHK_00994 7.3e-166 metF 1.5.1.20 E reductase
NMPABLHK_00995 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NMPABLHK_00997 1.1e-220 sip L Belongs to the 'phage' integrase family
NMPABLHK_01002 9.2e-13
NMPABLHK_01003 6.9e-22
NMPABLHK_01004 3e-164 KL Phage plasmid primase P4 family
NMPABLHK_01005 2e-296 S DNA primase
NMPABLHK_01007 5e-12
NMPABLHK_01008 9e-08
NMPABLHK_01009 1.7e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
NMPABLHK_01010 6.5e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NMPABLHK_01011 3.1e-81 ypmB S Protein conserved in bacteria
NMPABLHK_01012 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NMPABLHK_01013 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NMPABLHK_01014 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
NMPABLHK_01015 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
NMPABLHK_01016 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NMPABLHK_01017 9.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NMPABLHK_01018 1.3e-69 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NMPABLHK_01019 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMPABLHK_01020 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMPABLHK_01021 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NMPABLHK_01022 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
NMPABLHK_01023 1.8e-107 rsmC 2.1.1.172 J Methyltransferase small domain protein
NMPABLHK_01024 1.9e-172 coaA 2.7.1.33 F Pantothenic acid kinase
NMPABLHK_01025 2.1e-30 rpsT J rRNA binding
NMPABLHK_01026 1.4e-54
NMPABLHK_01027 0.0 ctpE P E1-E2 ATPase
NMPABLHK_01028 3.9e-26
NMPABLHK_01029 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMPABLHK_01030 5.1e-47 L transposase activity
NMPABLHK_01031 1.4e-81 K transcriptional regulator, MerR family
NMPABLHK_01032 1.3e-105 dnaQ 2.7.7.7 L DNA polymerase III
NMPABLHK_01033 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
NMPABLHK_01034 7.4e-64 XK27_02560 S cog cog2151
NMPABLHK_01035 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NMPABLHK_01036 7.7e-227 ytfP S Flavoprotein
NMPABLHK_01038 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NMPABLHK_01039 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
NMPABLHK_01040 2.7e-183 ecsB U ABC transporter
NMPABLHK_01041 2.3e-133 ecsA V abc transporter atp-binding protein
NMPABLHK_01042 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NMPABLHK_01043 6e-11
NMPABLHK_01044 1.4e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMPABLHK_01045 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMPABLHK_01046 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NMPABLHK_01047 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMPABLHK_01048 1.1e-142 purR 2.4.2.7 F operon repressor
NMPABLHK_01049 1.8e-178 cbf S 3'-5' exoribonuclease yhaM
NMPABLHK_01050 6.9e-173 rmuC S RmuC domain protein
NMPABLHK_01051 1.8e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
NMPABLHK_01052 3e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NMPABLHK_01053 2.6e-163 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NMPABLHK_01055 1.1e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMPABLHK_01056 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMPABLHK_01057 1.4e-144 tatD L Hydrolase, tatd
NMPABLHK_01058 2.5e-26 yccU S CoA-binding protein
NMPABLHK_01059 4.8e-51 trxA O Belongs to the thioredoxin family
NMPABLHK_01060 7.8e-143 S Macro domain protein
NMPABLHK_01061 3.1e-10 L thioesterase
NMPABLHK_01062 1.3e-54 bta 1.8.1.8 CO cell redox homeostasis
NMPABLHK_01064 3.3e-95 ywlG S Belongs to the UPF0340 family
NMPABLHK_01065 1.2e-85 treR K trehalose operon
NMPABLHK_01066 5.8e-21 treR K DNA-binding transcription factor activity
NMPABLHK_01067 1.4e-54 treB 2.7.1.201 G PTS System
NMPABLHK_01068 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NMPABLHK_01069 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NMPABLHK_01070 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NMPABLHK_01071 0.0 pepO 3.4.24.71 O Peptidase family M13
NMPABLHK_01072 3.1e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
NMPABLHK_01073 6.3e-132 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NMPABLHK_01074 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NMPABLHK_01075 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
NMPABLHK_01076 5.5e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NMPABLHK_01077 9.2e-278 thrC 4.2.3.1 E Threonine synthase
NMPABLHK_01078 3.2e-226 norN V Mate efflux family protein
NMPABLHK_01079 1.8e-57 asp S cog cog1302
NMPABLHK_01080 7.6e-305 yloV S kinase related to dihydroxyacetone kinase
NMPABLHK_01081 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NMPABLHK_01083 3.6e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
NMPABLHK_01084 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
NMPABLHK_01085 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
NMPABLHK_01086 1.2e-143 2.4.2.3 F Phosphorylase superfamily
NMPABLHK_01089 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
NMPABLHK_01090 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
NMPABLHK_01091 6e-08 S Hydrolases of the alpha beta superfamily
NMPABLHK_01092 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
NMPABLHK_01093 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NMPABLHK_01094 1.8e-159 czcD P cation diffusion facilitator family transporter
NMPABLHK_01095 9e-98 K Transcriptional regulator, TetR family
NMPABLHK_01096 1.6e-10
NMPABLHK_01097 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMPABLHK_01098 6.4e-104 V ABC transporter (Permease
NMPABLHK_01099 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NMPABLHK_01100 1e-163 M LysM domain
NMPABLHK_01101 7.6e-16
NMPABLHK_01102 2.3e-175 S hydrolase
NMPABLHK_01103 6.6e-116 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NMPABLHK_01104 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMPABLHK_01105 2.8e-155 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
NMPABLHK_01106 2.7e-27 P Hemerythrin HHE cation binding domain protein
NMPABLHK_01107 1.6e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMPABLHK_01108 1.4e-23 MA20_36090 S Protein of unknown function (DUF2974)
NMPABLHK_01109 9.1e-27 MA20_36090 S Protein of unknown function (DUF2974)
NMPABLHK_01110 8.7e-45 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMPABLHK_01111 7.6e-71 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMPABLHK_01112 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NMPABLHK_01113 1.4e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMPABLHK_01114 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NMPABLHK_01115 6.9e-144 S SseB protein N-terminal domain
NMPABLHK_01116 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
NMPABLHK_01117 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMPABLHK_01118 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMPABLHK_01121 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMPABLHK_01122 3.5e-91 yacP S RNA-binding protein containing a PIN domain
NMPABLHK_01123 3.4e-155 degV S DegV family
NMPABLHK_01124 1.8e-31 K helix-turn-helix
NMPABLHK_01125 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMPABLHK_01126 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMPABLHK_01127 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NMPABLHK_01128 2.8e-93 pat 2.3.1.183 M acetyltransferase
NMPABLHK_01129 7.3e-82 alkD L Dna alkylation repair
NMPABLHK_01130 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMPABLHK_01131 2.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMPABLHK_01132 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NMPABLHK_01133 0.0 smc D Required for chromosome condensation and partitioning
NMPABLHK_01134 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMPABLHK_01135 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMPABLHK_01136 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMPABLHK_01138 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
NMPABLHK_01139 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMPABLHK_01141 2e-86 S ECF-type riboflavin transporter, S component
NMPABLHK_01142 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NMPABLHK_01143 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
NMPABLHK_01144 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
NMPABLHK_01145 1.9e-294 yfmM S abc transporter atp-binding protein
NMPABLHK_01146 3.4e-258 noxE P NADH oxidase
NMPABLHK_01147 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMPABLHK_01148 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMPABLHK_01149 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
NMPABLHK_01150 1.4e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
NMPABLHK_01151 1.8e-165 ypuA S secreted protein
NMPABLHK_01152 3.3e-26 L Transposase (IS116 IS110 IS902 family)
NMPABLHK_01153 4.2e-71 L Transposase (IS116 IS110 IS902 family)
NMPABLHK_01155 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMPABLHK_01156 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMPABLHK_01157 2.2e-34 nrdH O Glutaredoxin
NMPABLHK_01158 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NMPABLHK_01159 6.7e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
NMPABLHK_01160 2.3e-223 icd 1.1.1.42 C Isocitrate dehydrogenase
NMPABLHK_01161 7.9e-39 ptsH G phosphocarrier protein Hpr
NMPABLHK_01162 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMPABLHK_01163 1.1e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
NMPABLHK_01164 9.6e-29 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NMPABLHK_01165 9.3e-179 yfmL 3.6.4.13 L DEAD DEAH box helicase
NMPABLHK_01166 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NMPABLHK_01167 0.0 uup S abc transporter atp-binding protein
NMPABLHK_01168 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
NMPABLHK_01169 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMPABLHK_01170 8.7e-150 cobQ S glutamine amidotransferase
NMPABLHK_01171 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
NMPABLHK_01172 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMPABLHK_01173 6e-169 ybbR S Protein conserved in bacteria
NMPABLHK_01174 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMPABLHK_01175 1.7e-70 gtrA S GtrA-like protein
NMPABLHK_01176 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NMPABLHK_01177 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMPABLHK_01178 2.3e-14 zupT P Mediates zinc uptake. May also transport other divalent cations
NMPABLHK_01179 6.4e-29 zupT P transporter
NMPABLHK_01180 1.6e-207 yurR 1.4.5.1 E oxidoreductase
NMPABLHK_01181 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NMPABLHK_01182 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NMPABLHK_01183 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NMPABLHK_01186 1.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
NMPABLHK_01187 6.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
NMPABLHK_01188 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NMPABLHK_01189 1.1e-121 ylfI S tigr01906
NMPABLHK_01190 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NMPABLHK_01191 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NMPABLHK_01192 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
NMPABLHK_01193 1.3e-22 XK27_08085
NMPABLHK_01194 5.2e-36 L transposase activity
NMPABLHK_01195 3.7e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NMPABLHK_01196 7.7e-128 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMPABLHK_01197 3e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMPABLHK_01198 3.8e-17 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
NMPABLHK_01199 3.9e-24 3.4.16.4 M Belongs to the peptidase S11 family
NMPABLHK_01200 1.3e-125 3.4.16.4 M Belongs to the peptidase S11 family
NMPABLHK_01201 1.3e-159 rssA S Phospholipase, patatin family
NMPABLHK_01202 6.1e-79 estA E GDSL-like protein
NMPABLHK_01203 2.6e-15 estA E Lysophospholipase L1 and related esterases
NMPABLHK_01204 2e-294 S unusual protein kinase
NMPABLHK_01205 4.9e-39 S granule-associated protein
NMPABLHK_01206 2.1e-35 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMPABLHK_01207 3.5e-138 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMPABLHK_01208 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMPABLHK_01209 1.3e-199 S hmm pf01594
NMPABLHK_01210 3.9e-61 G Belongs to the phosphoglycerate mutase family
NMPABLHK_01211 3.5e-29 G Belongs to the phosphoglycerate mutase family
NMPABLHK_01212 7.6e-70 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
NMPABLHK_01213 1.4e-96 V VanZ like family
NMPABLHK_01214 1.1e-29 yyzM S Protein conserved in bacteria
NMPABLHK_01215 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NMPABLHK_01216 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NMPABLHK_01217 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMPABLHK_01218 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NMPABLHK_01219 2.7e-61 divIC D Septum formation initiator
NMPABLHK_01221 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
NMPABLHK_01222 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NMPABLHK_01223 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NMPABLHK_01224 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMPABLHK_01225 2.4e-164 L Transposase
NMPABLHK_01226 3.8e-31 hmpT S membrane
NMPABLHK_01227 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
NMPABLHK_01228 7.7e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NMPABLHK_01229 3.1e-185 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NMPABLHK_01230 7.5e-298 dnaK O Heat shock 70 kDa protein
NMPABLHK_01231 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMPABLHK_01232 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NMPABLHK_01233 1.3e-102 acmA 3.2.1.17 NU amidase activity
NMPABLHK_01234 2.1e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NMPABLHK_01235 2.4e-135 ais G Phosphoglycerate mutase
NMPABLHK_01236 1.7e-243 XK27_08635 S UPF0210 protein
NMPABLHK_01237 3.6e-39 gcvR T UPF0237 protein
NMPABLHK_01238 1.5e-55 capA M Bacterial capsule synthesis protein
NMPABLHK_01239 4.3e-109 capA M Bacterial capsule synthesis protein
NMPABLHK_01240 1.2e-42 capA M Bacterial capsule synthesis protein PGA_cap
NMPABLHK_01241 3.5e-188 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
NMPABLHK_01242 2.2e-105
NMPABLHK_01243 1e-136 S Protein conserved in bacteria
NMPABLHK_01244 6.6e-306 hsdM 2.1.1.72 V type I restriction-modification system
NMPABLHK_01245 5.9e-22 S PD-(D/E)XK nuclease family transposase
NMPABLHK_01246 1e-36 spd F DNA RNA non-specific endonuclease
NMPABLHK_01247 9.9e-90 spd F DNA RNA non-specific endonuclease
NMPABLHK_01248 9e-93 lemA S LemA family
NMPABLHK_01249 6.4e-133 htpX O Belongs to the peptidase M48B family
NMPABLHK_01250 1.8e-73 S Psort location CytoplasmicMembrane, score
NMPABLHK_01251 6.2e-56 S Domain of unknown function (DUF4430)
NMPABLHK_01252 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NMPABLHK_01253 1.9e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
NMPABLHK_01254 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
NMPABLHK_01255 2.7e-285 XK27_07020 S Belongs to the UPF0371 family
NMPABLHK_01257 1.1e-37 BP1961 P nitric oxide dioxygenase activity
NMPABLHK_01258 1.6e-53 K response regulator
NMPABLHK_01259 9.3e-72 S Signal peptide protein, YSIRK family
NMPABLHK_01260 4.5e-61
NMPABLHK_01261 5.5e-272 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMPABLHK_01262 1.9e-35
NMPABLHK_01263 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
NMPABLHK_01264 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
NMPABLHK_01265 5.8e-109 MA20_06410 E LysE type translocator
NMPABLHK_01266 5.6e-08
NMPABLHK_01267 2.7e-09
NMPABLHK_01268 0.0 M family 8
NMPABLHK_01269 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
NMPABLHK_01270 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
NMPABLHK_01271 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NMPABLHK_01272 4.9e-227 pyrP F uracil Permease
NMPABLHK_01273 1.1e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMPABLHK_01274 1e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMPABLHK_01275 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMPABLHK_01276 1.8e-167 fhuR K transcriptional regulator (lysR family)
NMPABLHK_01281 1.1e-37 P membrane protein (DUF2207)
NMPABLHK_01282 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NMPABLHK_01283 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMPABLHK_01284 1.1e-200 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMPABLHK_01285 0.0 lpdA 1.8.1.4 C Dehydrogenase
NMPABLHK_01286 6.4e-11 3.5.1.28 NU amidase activity
NMPABLHK_01287 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
NMPABLHK_01288 8.6e-187 3.5.1.28 M GBS Bsp-like repeat
NMPABLHK_01289 1.5e-133 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NMPABLHK_01290 7.6e-66 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NMPABLHK_01291 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NMPABLHK_01292 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NMPABLHK_01293 1.5e-33 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NMPABLHK_01294 4.2e-44 yrzB S Belongs to the UPF0473 family
NMPABLHK_01295 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMPABLHK_01296 2.8e-44 yrzL S Belongs to the UPF0297 family
NMPABLHK_01297 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NMPABLHK_01298 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
NMPABLHK_01300 3.5e-216 int L Belongs to the 'phage' integrase family
NMPABLHK_01301 1.9e-18 S Domain of unknown function (DUF3173)
NMPABLHK_01302 1.4e-107 L Replication initiation factor
NMPABLHK_01303 1e-36 L Replication initiation factor
NMPABLHK_01304 1.7e-90 K sequence-specific DNA binding
NMPABLHK_01305 3.9e-287 V ABC transporter transmembrane region
NMPABLHK_01306 3.4e-191 C Radical SAM
NMPABLHK_01308 1.4e-127 Z012_04635 K sequence-specific DNA binding
NMPABLHK_01309 1.7e-52 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMPABLHK_01310 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMPABLHK_01311 0.0 clpC O Belongs to the ClpA ClpB family
NMPABLHK_01312 1.8e-75 ctsR K Belongs to the CtsR family
NMPABLHK_01313 5.5e-83 S Putative small multi-drug export protein
NMPABLHK_01314 1.7e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMPABLHK_01315 1.6e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NMPABLHK_01318 3.8e-87 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NMPABLHK_01319 1.9e-22 yocD 3.4.17.13 V carboxypeptidase activity
NMPABLHK_01320 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NMPABLHK_01321 1e-33 L Transposase
NMPABLHK_01322 1e-13 rpmH J Ribosomal protein L34
NMPABLHK_01323 2e-186 jag S RNA-binding protein
NMPABLHK_01324 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMPABLHK_01325 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NMPABLHK_01326 1.9e-264 argH 4.3.2.1 E Argininosuccinate lyase
NMPABLHK_01327 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NMPABLHK_01328 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMPABLHK_01329 6.7e-81 amiA E transmembrane transport
NMPABLHK_01330 2e-41 amiA E transmembrane transport
NMPABLHK_01331 4.2e-90 amiA E ABC transporter, substrate-binding protein, family 5
NMPABLHK_01332 7.8e-28 amiA E ABC transporter, substrate-binding protein, family 5
NMPABLHK_01333 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NMPABLHK_01334 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMPABLHK_01335 9.2e-51 S Protein of unknown function (DUF3397)
NMPABLHK_01336 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
NMPABLHK_01337 9.3e-34 WQ51_05710 S Mitochondrial biogenesis AIM24
NMPABLHK_01338 6.8e-32 WQ51_05710 S Mitochondrial biogenesis AIM24
NMPABLHK_01339 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
NMPABLHK_01340 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMPABLHK_01341 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
NMPABLHK_01342 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
NMPABLHK_01343 4.3e-77 XK27_09620 S reductase
NMPABLHK_01344 9e-62 XK27_09615 C reductase
NMPABLHK_01345 1e-141 XK27_09615 C reductase
NMPABLHK_01346 3.2e-62 fnt P Formate nitrite transporter
NMPABLHK_01347 5.5e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
NMPABLHK_01348 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NMPABLHK_01349 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMPABLHK_01350 5.2e-119 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NMPABLHK_01351 9.1e-95 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMPABLHK_01352 7.9e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NMPABLHK_01353 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NMPABLHK_01354 2.7e-48 S glycolate biosynthetic process
NMPABLHK_01355 1.5e-64 S phosphatase activity
NMPABLHK_01356 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
NMPABLHK_01359 1.2e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NMPABLHK_01360 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMPABLHK_01361 8.3e-37 yeeD O sulfur carrier activity
NMPABLHK_01362 2.8e-193 yeeE S Sulphur transport
NMPABLHK_01363 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMPABLHK_01364 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMPABLHK_01365 4.1e-09 S Domain of unknown function (DUF4651)
NMPABLHK_01366 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NMPABLHK_01367 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMPABLHK_01368 1.8e-111 S CAAX amino terminal protease family protein
NMPABLHK_01370 5e-67 V CAAX protease self-immunity
NMPABLHK_01371 1.4e-33 V CAAX protease self-immunity
NMPABLHK_01372 8.8e-27 lanR K sequence-specific DNA binding
NMPABLHK_01373 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMPABLHK_01374 5.9e-177 ytxK 2.1.1.72 L DNA methylase
NMPABLHK_01375 2e-12 comGF U Putative Competence protein ComGF
NMPABLHK_01376 1.5e-71 comGF U Competence protein ComGF
NMPABLHK_01377 1.4e-15 NU Type II secretory pathway pseudopilin
NMPABLHK_01378 1.8e-57 cglD NU Competence protein
NMPABLHK_01379 8.5e-43 comGC U Required for transformation and DNA binding
NMPABLHK_01380 1.1e-156 cglB U protein transport across the cell outer membrane
NMPABLHK_01381 4.5e-177 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMPABLHK_01382 1e-68 S cog cog4699
NMPABLHK_01383 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMPABLHK_01384 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMPABLHK_01385 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMPABLHK_01386 9.3e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMPABLHK_01387 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NMPABLHK_01388 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
NMPABLHK_01389 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
NMPABLHK_01390 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NMPABLHK_01391 1e-114 papP P ABC transporter (Permease
NMPABLHK_01392 3.5e-115 P ABC transporter (Permease
NMPABLHK_01393 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
NMPABLHK_01394 1.1e-155 cjaA ET ABC transporter substrate-binding protein
NMPABLHK_01398 1e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NMPABLHK_01399 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
NMPABLHK_01400 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NMPABLHK_01401 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
NMPABLHK_01402 4e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NMPABLHK_01403 2e-82 queD 4.1.2.50, 4.2.3.12 H synthase
NMPABLHK_01404 2.9e-136 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NMPABLHK_01405 6.5e-95 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
NMPABLHK_01406 7.7e-20 D nuclear chromosome segregation
NMPABLHK_01407 7.4e-138 yejC S cyclic nucleotide-binding protein
NMPABLHK_01408 1.2e-163 rapZ S Displays ATPase and GTPase activities
NMPABLHK_01409 9.6e-183 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NMPABLHK_01410 8.7e-162 whiA K May be required for sporulation
NMPABLHK_01411 2.8e-90 pepD E Dipeptidase
NMPABLHK_01412 5.8e-41 pepD E dipeptidase activity
NMPABLHK_01413 2.6e-10
NMPABLHK_01416 1.9e-07
NMPABLHK_01421 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMPABLHK_01422 2.3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NMPABLHK_01423 1.9e-36 XK27_02060 S Transglycosylase associated protein
NMPABLHK_01424 2.6e-55 badR K DNA-binding transcription factor activity
NMPABLHK_01425 3.5e-97 S reductase
NMPABLHK_01426 1e-110 L Integrase core domain protein
NMPABLHK_01427 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
NMPABLHK_01428 1.4e-40 tatD L Hydrolase, tatd
NMPABLHK_01429 3.8e-45 oppF P Belongs to the ABC transporter superfamily
NMPABLHK_01430 1e-23 oppF P Belongs to the ABC transporter superfamily
NMPABLHK_01431 4.1e-158 L COG2801 Transposase and inactivated derivatives
NMPABLHK_01432 8.1e-45 L Transposase
NMPABLHK_01433 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NMPABLHK_01434 3.8e-205 EGP Transmembrane secretion effector
NMPABLHK_01435 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
NMPABLHK_01436 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMPABLHK_01437 3e-44 ymbI L transposase activity
NMPABLHK_01439 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
NMPABLHK_01440 0.0 3.6.3.8 P cation transport ATPase
NMPABLHK_01442 2.3e-20 yecS P amino acid transport
NMPABLHK_01443 1.4e-62 yecS P ABC transporter (Permease
NMPABLHK_01444 1.6e-266 dtpT E transporter
NMPABLHK_01445 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMPABLHK_01446 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NMPABLHK_01447 3.4e-77 L Transposase
NMPABLHK_01448 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NMPABLHK_01449 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMPABLHK_01450 8.2e-28 ytrF V efflux transmembrane transporter activity
NMPABLHK_01451 3.1e-31 V efflux transmembrane transporter activity
NMPABLHK_01452 3.6e-35 V efflux transmembrane transporter activity
NMPABLHK_01453 2.2e-134 2.1.1.223 S Putative SAM-dependent methyltransferase
NMPABLHK_01454 1.1e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMPABLHK_01455 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NMPABLHK_01456 5.1e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
NMPABLHK_01457 3.8e-122 sdaAB 4.3.1.17 E L-serine dehydratase
NMPABLHK_01458 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NMPABLHK_01459 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMPABLHK_01460 1e-134 parB K Belongs to the ParB family
NMPABLHK_01461 1.5e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
NMPABLHK_01462 1.1e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMPABLHK_01463 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
NMPABLHK_01467 0.0 XK27_10405 S Bacterial membrane protein YfhO
NMPABLHK_01468 6.7e-306 ybiT S abc transporter atp-binding protein
NMPABLHK_01469 1.1e-153 yvjA S membrane
NMPABLHK_01470 8.2e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NMPABLHK_01471 1.5e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NMPABLHK_01472 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMPABLHK_01473 1.6e-45 yaaA S S4 domain protein YaaA
NMPABLHK_01474 4.8e-235 ymfF S Peptidase M16
NMPABLHK_01475 1.1e-242 ymfH S Peptidase M16
NMPABLHK_01476 3.7e-138 ymfM S sequence-specific DNA binding
NMPABLHK_01477 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMPABLHK_01478 7.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMPABLHK_01479 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMPABLHK_01480 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMPABLHK_01481 3.1e-93 lytE M LysM domain protein
NMPABLHK_01482 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
NMPABLHK_01483 0.0 S Bacterial membrane protein, YfhO
NMPABLHK_01484 3.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NMPABLHK_01485 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NMPABLHK_01486 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NMPABLHK_01487 3.9e-70 rplI J binds to the 23S rRNA
NMPABLHK_01488 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NMPABLHK_01489 8.2e-48 veg S Biofilm formation stimulator VEG
NMPABLHK_01490 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMPABLHK_01491 2.7e-08
NMPABLHK_01492 4.8e-55 ypaA M Membrane
NMPABLHK_01493 6.4e-96 XK27_06935 K transcriptional regulator
NMPABLHK_01494 3.9e-161 XK27_06930 V domain protein
NMPABLHK_01495 1.8e-88 S Putative adhesin
NMPABLHK_01496 3.1e-19 XK27_06920 S Protein of unknown function (DUF1700)
NMPABLHK_01498 1.7e-23 K negative regulation of transcription, DNA-templated
NMPABLHK_01499 4e-19 K negative regulation of transcription, DNA-templated
NMPABLHK_01500 3.4e-13 nudL L hydrolase
NMPABLHK_01501 7.2e-95 nudL L hydrolase
NMPABLHK_01502 4.9e-12 K CsbD-like
NMPABLHK_01503 1.1e-71 M Protein conserved in bacteria
NMPABLHK_01504 1.8e-23 S Small integral membrane protein
NMPABLHK_01505 3.1e-101
NMPABLHK_01506 3.7e-27 S Membrane
NMPABLHK_01508 2.7e-95 S Hydrophobic domain protein
NMPABLHK_01509 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
NMPABLHK_01511 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMPABLHK_01512 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NMPABLHK_01513 9.2e-36 metE 2.1.1.14 E Methionine synthase
NMPABLHK_01514 7.6e-64 metE 2.1.1.14 E Methionine synthase
NMPABLHK_01515 5.7e-52 metE 2.1.1.14 E Methionine synthase
NMPABLHK_01516 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
NMPABLHK_01518 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NMPABLHK_01519 9.9e-169 XK27_01785 S cog cog1284
NMPABLHK_01520 1.8e-147 yaaA S Belongs to the UPF0246 family
NMPABLHK_01521 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NMPABLHK_01522 2.6e-91 XK27_10930 K acetyltransferase
NMPABLHK_01523 7.5e-14
NMPABLHK_01524 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NMPABLHK_01525 2.3e-301 ccs S the current gene model (or a revised gene model) may contain a frame shift
NMPABLHK_01526 1.8e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMPABLHK_01527 4.2e-195 desK 2.7.13.3 T Histidine kinase
NMPABLHK_01528 7.4e-135 yvfS V ABC-2 type transporter
NMPABLHK_01529 2.1e-160 XK27_09825 V 'abc transporter, ATP-binding protein
NMPABLHK_01533 1.1e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMPABLHK_01534 1.3e-148 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NMPABLHK_01535 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
NMPABLHK_01536 4.3e-118 S TraX protein
NMPABLHK_01538 3.7e-157 glcU U Glucose uptake
NMPABLHK_01539 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
NMPABLHK_01540 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
NMPABLHK_01541 1.4e-150 L Integrase core domain protein
NMPABLHK_01542 1.8e-87 L transposase activity
NMPABLHK_01544 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NMPABLHK_01545 1e-128 V ABC transporter (permease)
NMPABLHK_01546 1.6e-18 L Integrase core domain
NMPABLHK_01547 4.7e-115 hrtB V MacB-like periplasmic core domain
NMPABLHK_01549 3e-92 S MucBP domain
NMPABLHK_01550 6.5e-50 M YSIRK type signal peptide
NMPABLHK_01551 0.0 M the current gene model (or a revised gene model) may contain a
NMPABLHK_01553 0.0 mdlB V abc transporter atp-binding protein
NMPABLHK_01554 0.0 lmrA V abc transporter atp-binding protein
NMPABLHK_01555 4.6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NMPABLHK_01556 5e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMPABLHK_01557 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
NMPABLHK_01558 2.5e-132 rr02 KT response regulator
NMPABLHK_01559 7.1e-214 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMPABLHK_01560 2.8e-168 V ABC transporter
NMPABLHK_01561 5.4e-122 sagI S ABC-2 type transporter
NMPABLHK_01562 2.4e-197 yceA S Belongs to the UPF0176 family
NMPABLHK_01563 8e-28 XK27_00085 K Transcriptional
NMPABLHK_01564 1.1e-22
NMPABLHK_01565 2.8e-145 deoD_1 2.4.2.3 F Phosphorylase superfamily
NMPABLHK_01566 8.7e-114 S VIT family
NMPABLHK_01567 8.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMPABLHK_01568 8e-221 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NMPABLHK_01569 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
NMPABLHK_01570 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
NMPABLHK_01571 6.1e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NMPABLHK_01572 4.6e-105 GBS0088 J protein conserved in bacteria
NMPABLHK_01573 2.5e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NMPABLHK_01574 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NMPABLHK_01575 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
NMPABLHK_01576 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NMPABLHK_01577 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMPABLHK_01578 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
NMPABLHK_01579 2.5e-21
NMPABLHK_01580 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMPABLHK_01582 3.5e-07 U protein secretion
NMPABLHK_01583 2.1e-50 U protein secretion
NMPABLHK_01585 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
NMPABLHK_01586 1.8e-248 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NMPABLHK_01587 4.9e-21 XK27_13030
NMPABLHK_01588 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMPABLHK_01589 8.9e-57 S hydrolase activity, acting on ester bonds
NMPABLHK_01590 9.4e-71 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMPABLHK_01591 8.6e-167 S Protein of unknown function (DUF3114)
NMPABLHK_01592 1.2e-22 S Protein of unknown function (DUF3114)
NMPABLHK_01593 1.5e-118 yqfA K protein, Hemolysin III
NMPABLHK_01594 1e-25 K hmm pf08876
NMPABLHK_01595 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NMPABLHK_01596 1.7e-218 mvaS 2.3.3.10 I synthase
NMPABLHK_01597 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMPABLHK_01598 1.4e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMPABLHK_01599 9.7e-22
NMPABLHK_01600 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMPABLHK_01601 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NMPABLHK_01602 5.2e-251 mmuP E amino acid
NMPABLHK_01603 1.2e-177 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
NMPABLHK_01604 1.4e-29 S Domain of unknown function (DUF1912)
NMPABLHK_01605 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
NMPABLHK_01606 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
NMPABLHK_01607 1.9e-33
NMPABLHK_01608 0.0 amiA E ABC transporter, substrate-binding protein, family 5
NMPABLHK_01609 4.2e-278 amiC P ABC transporter (Permease
NMPABLHK_01610 4.9e-168 amiD P ABC transporter (Permease
NMPABLHK_01611 2.2e-204 oppD P Belongs to the ABC transporter superfamily
NMPABLHK_01612 4.3e-172 oppF P Belongs to the ABC transporter superfamily
NMPABLHK_01613 5.6e-133 V ATPase activity
NMPABLHK_01614 9.8e-121 skfE V abc transporter atp-binding protein
NMPABLHK_01615 8.6e-63 yvoA_1 K Transcriptional
NMPABLHK_01616 2.1e-148 supH S overlaps another CDS with the same product name
NMPABLHK_01617 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
NMPABLHK_01618 9.7e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NMPABLHK_01619 2e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NMPABLHK_01620 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
NMPABLHK_01621 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMPABLHK_01622 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMPABLHK_01623 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMPABLHK_01624 9e-133 stp 3.1.3.16 T phosphatase
NMPABLHK_01625 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NMPABLHK_01626 3.7e-120 yvqF KT membrane
NMPABLHK_01627 5.8e-175 vraS 2.7.13.3 T Histidine kinase
NMPABLHK_01628 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMPABLHK_01631 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMPABLHK_01632 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NMPABLHK_01633 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NMPABLHK_01634 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NMPABLHK_01635 2.3e-87 L Transposase
NMPABLHK_01636 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
NMPABLHK_01637 4.3e-40 V abc transporter atp-binding protein
NMPABLHK_01638 2.5e-101 V abc transporter atp-binding protein
NMPABLHK_01639 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NMPABLHK_01640 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
NMPABLHK_01641 1.2e-25 L transposition
NMPABLHK_01642 2.7e-08 L Integrase core domain protein
NMPABLHK_01643 1.8e-184 galR K Transcriptional regulator
NMPABLHK_01644 5.6e-222 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMPABLHK_01645 8e-290 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
NMPABLHK_01646 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NMPABLHK_01647 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NMPABLHK_01648 0.0 lacS G transporter
NMPABLHK_01649 0.0 lacL 3.2.1.23 G -beta-galactosidase
NMPABLHK_01650 5.3e-231 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NMPABLHK_01651 0.0 sbcC L ATPase involved in DNA repair
NMPABLHK_01652 3.5e-28 3.4.13.21 I Protein conserved in bacteria
NMPABLHK_01654 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMPABLHK_01655 1.8e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMPABLHK_01656 3.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NMPABLHK_01657 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NMPABLHK_01658 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NMPABLHK_01659 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMPABLHK_01661 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMPABLHK_01662 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
NMPABLHK_01663 0.0 scrA 2.7.1.211 G pts system
NMPABLHK_01664 5.4e-291 scrB 3.2.1.26 GH32 G invertase
NMPABLHK_01665 7.5e-180 scrR K Transcriptional
NMPABLHK_01666 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMPABLHK_01667 3.4e-62 yqhY S protein conserved in bacteria
NMPABLHK_01668 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMPABLHK_01669 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
NMPABLHK_01670 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
NMPABLHK_01672 8e-44 V 'abc transporter, ATP-binding protein
NMPABLHK_01673 3.8e-58 V 'abc transporter, ATP-binding protein
NMPABLHK_01676 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NMPABLHK_01677 2e-169 corA P COG0598 Mg2 and Co2 transporters
NMPABLHK_01678 3.1e-124 XK27_01040 S Pfam PF06570
NMPABLHK_01680 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMPABLHK_01681 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMPABLHK_01682 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
NMPABLHK_01683 3.6e-41 XK27_05745
NMPABLHK_01684 2.5e-230 mutY L A G-specific adenine glycosylase
NMPABLHK_01690 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMPABLHK_01691 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMPABLHK_01692 1e-93 cvpA S toxin biosynthetic process
NMPABLHK_01693 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NMPABLHK_01694 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMPABLHK_01695 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NMPABLHK_01696 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMPABLHK_01697 2e-47 azlD E branched-chain amino acid
NMPABLHK_01698 1.3e-117 azlC E AzlC protein
NMPABLHK_01699 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMPABLHK_01700 1.3e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NMPABLHK_01701 4.3e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
NMPABLHK_01702 2.5e-33 ykzG S Belongs to the UPF0356 family
NMPABLHK_01703 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMPABLHK_01704 2.7e-40 pscB M CHAP domain protein
NMPABLHK_01705 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
NMPABLHK_01706 8.5e-63 glnR K Transcriptional regulator
NMPABLHK_01707 1.3e-87 S Fusaric acid resistance protein-like
NMPABLHK_01708 1.2e-51 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
NMPABLHK_01709 2.4e-256 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
NMPABLHK_01710 9.7e-119 cpsD D COG0489 ATPases involved in chromosome partitioning
NMPABLHK_01711 1.9e-116 cps4C M biosynthesis protein
NMPABLHK_01712 4.6e-137 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
NMPABLHK_01713 8e-258 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
NMPABLHK_01714 2.4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
NMPABLHK_01715 1.5e-30 yfeJ 6.3.5.2 F glutamine amidotransferase
NMPABLHK_01716 3.7e-67 yfeJ 6.3.5.2 F glutamine amidotransferase
NMPABLHK_01717 9.4e-66 clcA_2 P chloride
NMPABLHK_01718 4e-150 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NMPABLHK_01719 8.1e-41 S Protein of unknown function (DUF1697)
NMPABLHK_01720 3.8e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NMPABLHK_01721 1.7e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NMPABLHK_01723 9.1e-13 V Glucan-binding protein C
NMPABLHK_01724 2.4e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
NMPABLHK_01725 2.1e-276 pepV 3.5.1.18 E Dipeptidase
NMPABLHK_01726 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NMPABLHK_01727 6.9e-86 XK27_03610 K Gnat family
NMPABLHK_01728 4.7e-24 L Transposase
NMPABLHK_01729 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMPABLHK_01730 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NMPABLHK_01731 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMPABLHK_01732 6.6e-122 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NMPABLHK_01733 3.9e-15 M LysM domain
NMPABLHK_01734 2.9e-90 ebsA S Family of unknown function (DUF5322)
NMPABLHK_01735 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NMPABLHK_01736 4.2e-98 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NMPABLHK_01737 3.7e-224 G COG0457 FOG TPR repeat
NMPABLHK_01738 6.2e-176 yubA S permease
NMPABLHK_01739 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
NMPABLHK_01740 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NMPABLHK_01741 2.5e-124 ftsE D cell division ATP-binding protein FtsE
NMPABLHK_01742 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NMPABLHK_01743 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NMPABLHK_01744 1.1e-180 yjjH S Calcineurin-like phosphoesterase
NMPABLHK_01745 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NMPABLHK_01746 0.0 pacL 3.6.3.8 P cation transport ATPase
NMPABLHK_01747 2.6e-67 ywiB S Domain of unknown function (DUF1934)
NMPABLHK_01748 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
NMPABLHK_01749 1.2e-146 yidA S hydrolases of the HAD superfamily
NMPABLHK_01750 1.8e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
NMPABLHK_01751 2.1e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
NMPABLHK_01752 1.5e-247 vicK 2.7.13.3 T Histidine kinase
NMPABLHK_01753 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMPABLHK_01754 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
NMPABLHK_01755 3.1e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
NMPABLHK_01756 5.9e-118 gltJ P ABC transporter (Permease
NMPABLHK_01757 1.7e-111 tcyB_2 P ABC transporter (permease)
NMPABLHK_01758 2.4e-124 endA F DNA RNA non-specific endonuclease
NMPABLHK_01759 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
NMPABLHK_01760 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMPABLHK_01762 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NMPABLHK_01763 2.2e-21 G Domain of unknown function (DUF4832)
NMPABLHK_01764 4.5e-38 G Domain of unknown function (DUF4832)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)