ORF_ID e_value Gene_name EC_number CAZy COGs Description
ACFBBGHA_00003 1e-156 ydhU P Catalase
ACFBBGHA_00004 2.1e-215 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
ACFBBGHA_00005 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
ACFBBGHA_00006 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
ACFBBGHA_00007 1.1e-132 ydhQ K UTRA
ACFBBGHA_00008 2.5e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACFBBGHA_00009 3.4e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ACFBBGHA_00010 3.9e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
ACFBBGHA_00011 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
ACFBBGHA_00012 4.6e-200 pbuE EGP Major facilitator Superfamily
ACFBBGHA_00013 2.8e-97 ydhK M Protein of unknown function (DUF1541)
ACFBBGHA_00014 2.9e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
ACFBBGHA_00015 2.9e-84 K Acetyltransferase (GNAT) domain
ACFBBGHA_00017 4.6e-69 frataxin S Domain of unknown function (DU1801)
ACFBBGHA_00018 4.4e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
ACFBBGHA_00019 3.3e-124
ACFBBGHA_00020 4.5e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ACFBBGHA_00021 1.1e-242 ydhD M Glycosyl hydrolase
ACFBBGHA_00022 6.5e-122 ydhC K FCD
ACFBBGHA_00023 1.6e-121 ydhB S membrane transporter protein
ACFBBGHA_00024 1.1e-207 tcaB EGP Major facilitator Superfamily
ACFBBGHA_00025 2.4e-69 ydgJ K Winged helix DNA-binding domain
ACFBBGHA_00026 1e-113 drgA C nitroreductase
ACFBBGHA_00027 0.0 ydgH S drug exporters of the RND superfamily
ACFBBGHA_00028 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
ACFBBGHA_00029 4.7e-88 dinB S DinB family
ACFBBGHA_00030 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
ACFBBGHA_00031 1.8e-303 expZ S ABC transporter
ACFBBGHA_00032 1.3e-84 yycN 2.3.1.128 K Acetyltransferase
ACFBBGHA_00033 1.4e-51 S DoxX-like family
ACFBBGHA_00034 2.4e-96 K Bacterial regulatory proteins, tetR family
ACFBBGHA_00035 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
ACFBBGHA_00036 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
ACFBBGHA_00037 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
ACFBBGHA_00038 5.2e-122 ydfS S Protein of unknown function (DUF421)
ACFBBGHA_00039 4.4e-118 ydfR S Protein of unknown function (DUF421)
ACFBBGHA_00041 6.3e-29
ACFBBGHA_00042 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
ACFBBGHA_00044 1.7e-54 traF CO Thioredoxin
ACFBBGHA_00045 8.8e-63 mhqP S DoxX
ACFBBGHA_00046 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
ACFBBGHA_00047 6.2e-111 ydfN C nitroreductase
ACFBBGHA_00048 1.9e-153 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACFBBGHA_00049 9.2e-147 K Bacterial transcription activator, effector binding domain
ACFBBGHA_00050 9.3e-116 S Protein of unknown function (DUF554)
ACFBBGHA_00051 4e-175 S Alpha/beta hydrolase family
ACFBBGHA_00052 0.0 ydfJ S drug exporters of the RND superfamily
ACFBBGHA_00053 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ACFBBGHA_00054 1.8e-175 ydfH 2.7.13.3 T Histidine kinase
ACFBBGHA_00056 6.5e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACFBBGHA_00057 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
ACFBBGHA_00058 2.1e-114 ydfE S Flavin reductase like domain
ACFBBGHA_00059 8.7e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ACFBBGHA_00060 1.1e-159 ydfC EG EamA-like transporter family
ACFBBGHA_00061 6.1e-148 ydfB J GNAT acetyltransferase
ACFBBGHA_00062 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACFBBGHA_00063 2.8e-57 arsR K transcriptional
ACFBBGHA_00064 2.1e-103 ydeS K Transcriptional regulator
ACFBBGHA_00065 5.6e-193 ydeR EGP Major facilitator Superfamily
ACFBBGHA_00066 3.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
ACFBBGHA_00067 4.8e-69 ydeP K Transcriptional regulator
ACFBBGHA_00068 1.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
ACFBBGHA_00069 5.2e-56 K HxlR-like helix-turn-helix
ACFBBGHA_00070 1e-102 ydeN S Serine hydrolase
ACFBBGHA_00071 6e-73 maoC I N-terminal half of MaoC dehydratase
ACFBBGHA_00072 4.1e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ACFBBGHA_00073 1.6e-152 ydeK EG -transporter
ACFBBGHA_00074 8.8e-85 K Transcriptional regulator C-terminal region
ACFBBGHA_00075 1.8e-14 ptsH G PTS HPr component phosphorylation site
ACFBBGHA_00076 1.1e-31 S SNARE associated Golgi protein
ACFBBGHA_00077 6.9e-92
ACFBBGHA_00078 3.2e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
ACFBBGHA_00079 1.4e-44 ydeH
ACFBBGHA_00080 7.9e-217 ydeG EGP Major facilitator superfamily
ACFBBGHA_00081 2.1e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ACFBBGHA_00082 1.8e-164 ydeE K AraC family transcriptional regulator
ACFBBGHA_00083 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ACFBBGHA_00084 1.8e-164 rhaS5 K AraC-like ligand binding domain
ACFBBGHA_00085 2.8e-141 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
ACFBBGHA_00086 6.1e-79 carD K Transcription factor
ACFBBGHA_00087 8.7e-30 cspL K Cold shock
ACFBBGHA_00088 1.8e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
ACFBBGHA_00089 9.6e-40
ACFBBGHA_00090 3.4e-33 K Helix-turn-helix XRE-family like proteins
ACFBBGHA_00091 4.5e-15 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
ACFBBGHA_00092 5e-47 ydeH
ACFBBGHA_00093 9e-208 msbA2 3.6.3.44 V ABC transporter
ACFBBGHA_00094 9.8e-211 KLT Protein kinase domain
ACFBBGHA_00099 4.1e-159 KLT Protein kinase domain
ACFBBGHA_00111 3.4e-82 ydcK S Belongs to the SprT family
ACFBBGHA_00112 0.0 yhgF K COG2183 Transcriptional accessory protein
ACFBBGHA_00113 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
ACFBBGHA_00114 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACFBBGHA_00115 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
ACFBBGHA_00116 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
ACFBBGHA_00117 7.1e-189 rsbU 3.1.3.3 KT phosphatase
ACFBBGHA_00118 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
ACFBBGHA_00119 5.2e-57 rsbS T antagonist
ACFBBGHA_00120 1.3e-143 rsbR T Positive regulator of sigma-B
ACFBBGHA_00121 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
ACFBBGHA_00122 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
ACFBBGHA_00123 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACFBBGHA_00124 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
ACFBBGHA_00125 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
ACFBBGHA_00126 8.4e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
ACFBBGHA_00127 1.1e-259 ydbT S Membrane
ACFBBGHA_00128 2.1e-82 ydbS S Bacterial PH domain
ACFBBGHA_00129 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
ACFBBGHA_00130 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
ACFBBGHA_00131 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
ACFBBGHA_00132 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ACFBBGHA_00133 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACFBBGHA_00134 2.2e-07 S Fur-regulated basic protein A
ACFBBGHA_00135 1.1e-18 S Fur-regulated basic protein B
ACFBBGHA_00136 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
ACFBBGHA_00137 2.7e-52 ydbL
ACFBBGHA_00138 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ACFBBGHA_00139 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
ACFBBGHA_00140 9.7e-181 ydbI S AI-2E family transporter
ACFBBGHA_00141 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ACFBBGHA_00142 1.1e-119 dctR T COG4565 Response regulator of citrate malate metabolism
ACFBBGHA_00143 2.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ACFBBGHA_00144 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
ACFBBGHA_00145 2.3e-153 ydbD P Catalase
ACFBBGHA_00146 1.1e-62 ydbC S Domain of unknown function (DUF4937
ACFBBGHA_00147 8.9e-59 ydbB G Cupin domain
ACFBBGHA_00149 3.5e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
ACFBBGHA_00150 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
ACFBBGHA_00152 5e-224 mntH P H( )-stimulated, divalent metal cation uptake system
ACFBBGHA_00153 2.7e-39
ACFBBGHA_00154 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
ACFBBGHA_00155 2.1e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
ACFBBGHA_00156 0.0 ydaO E amino acid
ACFBBGHA_00157 0.0 ydaN S Bacterial cellulose synthase subunit
ACFBBGHA_00158 3.8e-232 ydaM M Glycosyl transferase family group 2
ACFBBGHA_00159 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
ACFBBGHA_00160 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
ACFBBGHA_00161 1.1e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
ACFBBGHA_00162 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACFBBGHA_00163 2.5e-74 lrpC K Transcriptional regulator
ACFBBGHA_00164 6.2e-45 ydzA EGP Major facilitator Superfamily
ACFBBGHA_00165 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
ACFBBGHA_00166 6.8e-77 ydaG 1.4.3.5 S general stress protein
ACFBBGHA_00167 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ACFBBGHA_00168 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
ACFBBGHA_00169 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_00170 9e-99 ydaC Q Methyltransferase domain
ACFBBGHA_00171 7.9e-293 ydaB IQ acyl-CoA ligase
ACFBBGHA_00172 0.0 mtlR K transcriptional regulator, MtlR
ACFBBGHA_00173 1.7e-173 ydhF S Oxidoreductase
ACFBBGHA_00174 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
ACFBBGHA_00175 8e-47 yczJ S biosynthesis
ACFBBGHA_00177 2.2e-119 ycsK E anatomical structure formation involved in morphogenesis
ACFBBGHA_00178 1.2e-132 kipR K Transcriptional regulator
ACFBBGHA_00179 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
ACFBBGHA_00180 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
ACFBBGHA_00181 3.7e-148 ycsI S Belongs to the D-glutamate cyclase family
ACFBBGHA_00182 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
ACFBBGHA_00183 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
ACFBBGHA_00184 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
ACFBBGHA_00186 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
ACFBBGHA_00187 4.8e-108 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
ACFBBGHA_00188 4.2e-98 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ACFBBGHA_00189 7.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
ACFBBGHA_00190 6.9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
ACFBBGHA_00191 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
ACFBBGHA_00192 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
ACFBBGHA_00193 3.4e-53
ACFBBGHA_00194 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
ACFBBGHA_00195 7.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
ACFBBGHA_00196 1.4e-99 ycnI S protein conserved in bacteria
ACFBBGHA_00197 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_00198 6.1e-149 glcU U Glucose uptake
ACFBBGHA_00199 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ACFBBGHA_00200 1.3e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACFBBGHA_00201 3.3e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ACFBBGHA_00202 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
ACFBBGHA_00203 1.6e-45 ycnE S Monooxygenase
ACFBBGHA_00204 2.2e-134 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
ACFBBGHA_00205 6.5e-154 ycnC K Transcriptional regulator
ACFBBGHA_00206 1.2e-250 ycnB EGP Major facilitator Superfamily
ACFBBGHA_00207 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
ACFBBGHA_00208 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
ACFBBGHA_00209 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_00210 4.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_00211 2.3e-238 lysC 2.7.2.4 E Belongs to the aspartokinase family
ACFBBGHA_00215 3.1e-71 S aspartate phosphatase
ACFBBGHA_00216 9.8e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
ACFBBGHA_00217 3.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_00218 1.5e-203 yclI V ABC transporter (permease) YclI
ACFBBGHA_00219 7.3e-121 yclH P ABC transporter
ACFBBGHA_00220 1.1e-195 gerKB F Spore germination protein
ACFBBGHA_00221 6.3e-232 gerKC S spore germination
ACFBBGHA_00222 1.1e-279 gerKA EG Spore germination protein
ACFBBGHA_00224 2.3e-296 yclG M Pectate lyase superfamily protein
ACFBBGHA_00225 1.6e-266 dtpT E amino acid peptide transporter
ACFBBGHA_00226 1.1e-153 yclE 3.4.11.5 S Alpha beta hydrolase
ACFBBGHA_00227 3.6e-79 yclD
ACFBBGHA_00228 4e-39 bsdD 4.1.1.61 S response to toxic substance
ACFBBGHA_00229 9.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
ACFBBGHA_00230 7.6e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
ACFBBGHA_00231 1.2e-160 bsdA K LysR substrate binding domain
ACFBBGHA_00232 1.1e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
ACFBBGHA_00233 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
ACFBBGHA_00234 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ACFBBGHA_00235 9.7e-115 yczE S membrane
ACFBBGHA_00236 2.9e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
ACFBBGHA_00237 5.1e-251 ycxD K GntR family transcriptional regulator
ACFBBGHA_00238 1.8e-154 ycxC EG EamA-like transporter family
ACFBBGHA_00239 7.9e-89 S YcxB-like protein
ACFBBGHA_00240 4e-226 EGP Major Facilitator Superfamily
ACFBBGHA_00241 5.7e-140 srfAD Q thioesterase
ACFBBGHA_00242 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
ACFBBGHA_00243 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_00244 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_00245 1.3e-63 hxlR K transcriptional
ACFBBGHA_00246 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
ACFBBGHA_00247 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
ACFBBGHA_00248 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
ACFBBGHA_00249 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
ACFBBGHA_00250 3.4e-70 nin S Competence protein J (ComJ)
ACFBBGHA_00251 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACFBBGHA_00252 3.5e-52 yckD S Protein of unknown function (DUF2680)
ACFBBGHA_00253 3.6e-47 yckC S membrane
ACFBBGHA_00255 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
ACFBBGHA_00256 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
ACFBBGHA_00257 2e-227 yciC S GTPases (G3E family)
ACFBBGHA_00258 3e-107 yciB M ErfK YbiS YcfS YnhG
ACFBBGHA_00259 3e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
ACFBBGHA_00260 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
ACFBBGHA_00261 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
ACFBBGHA_00262 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ACFBBGHA_00263 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACFBBGHA_00264 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
ACFBBGHA_00265 6e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
ACFBBGHA_00266 5.3e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
ACFBBGHA_00267 1e-159 I alpha/beta hydrolase fold
ACFBBGHA_00268 1e-138 ycgR S permeases
ACFBBGHA_00269 1.3e-146 ycgQ S membrane
ACFBBGHA_00270 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
ACFBBGHA_00271 2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACFBBGHA_00272 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
ACFBBGHA_00273 1.9e-169 ycgM E Proline dehydrogenase
ACFBBGHA_00274 4.1e-144 ycgL S Predicted nucleotidyltransferase
ACFBBGHA_00275 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
ACFBBGHA_00276 7.9e-177 oxyR3 K LysR substrate binding domain
ACFBBGHA_00277 4e-144 yafE Q ubiE/COQ5 methyltransferase family
ACFBBGHA_00278 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACFBBGHA_00280 2.1e-108 tmrB S AAA domain
ACFBBGHA_00281 4.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
ACFBBGHA_00282 9.3e-112 ycgI S Domain of unknown function (DUF1989)
ACFBBGHA_00283 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
ACFBBGHA_00284 1.2e-151 yqcI S YqcI/YcgG family
ACFBBGHA_00285 6.8e-113 ycgF E Lysine exporter protein LysE YggA
ACFBBGHA_00286 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
ACFBBGHA_00287 6.2e-269 mdr EGP Major facilitator Superfamily
ACFBBGHA_00288 8e-291 lctP C L-lactate permease
ACFBBGHA_00289 1.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
ACFBBGHA_00290 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
ACFBBGHA_00291 4.1e-81 ycgB
ACFBBGHA_00292 5.6e-256 ycgA S Membrane
ACFBBGHA_00293 4.1e-217 amhX S amidohydrolase
ACFBBGHA_00294 5.3e-164 opuAC E glycine betaine
ACFBBGHA_00295 1.3e-127 opuAB P glycine betaine
ACFBBGHA_00296 2.2e-227 proV 3.6.3.32 E glycine betaine
ACFBBGHA_00297 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
ACFBBGHA_00298 5.7e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
ACFBBGHA_00299 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
ACFBBGHA_00300 2e-192 yceH P Belongs to the TelA family
ACFBBGHA_00301 0.0 yceG S Putative component of 'biosynthetic module'
ACFBBGHA_00302 1.4e-136 terC P Protein of unknown function (DUF475)
ACFBBGHA_00303 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
ACFBBGHA_00304 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
ACFBBGHA_00305 5.6e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
ACFBBGHA_00306 5.6e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACFBBGHA_00307 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
ACFBBGHA_00308 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
ACFBBGHA_00309 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
ACFBBGHA_00310 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
ACFBBGHA_00311 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
ACFBBGHA_00312 1.2e-173 S response regulator aspartate phosphatase
ACFBBGHA_00313 1.1e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
ACFBBGHA_00314 6.1e-261 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_00315 3.4e-269 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_00316 6.6e-177 ycdA S Domain of unknown function (DUF5105)
ACFBBGHA_00317 1e-142 yccK C Aldo keto reductase
ACFBBGHA_00318 1.7e-22 yccK C Aldo keto reductase
ACFBBGHA_00319 2.7e-200 natB CP ABC-2 family transporter protein
ACFBBGHA_00320 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
ACFBBGHA_00321 1.2e-126 lytR_2 T LytTr DNA-binding domain
ACFBBGHA_00322 7.5e-156 2.7.13.3 T GHKL domain
ACFBBGHA_00323 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
ACFBBGHA_00324 2.1e-56 S RDD family
ACFBBGHA_00325 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
ACFBBGHA_00326 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
ACFBBGHA_00327 4.8e-102 yxaF K Transcriptional regulator
ACFBBGHA_00328 3e-225 lmrB EGP the major facilitator superfamily
ACFBBGHA_00329 3.6e-202 ycbU E Selenocysteine lyase
ACFBBGHA_00330 5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ACFBBGHA_00331 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACFBBGHA_00332 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
ACFBBGHA_00333 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
ACFBBGHA_00334 9.5e-135 ycbR T vWA found in TerF C terminus
ACFBBGHA_00335 1.3e-78 sleB 3.5.1.28 M Cell wall
ACFBBGHA_00336 4.1e-52 ycbP S Protein of unknown function (DUF2512)
ACFBBGHA_00337 2.5e-113 S ABC-2 family transporter protein
ACFBBGHA_00338 2.2e-165 ycbN V ABC transporter, ATP-binding protein
ACFBBGHA_00339 3.8e-168 T PhoQ Sensor
ACFBBGHA_00340 7.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_00341 2.9e-102 eamA1 EG spore germination
ACFBBGHA_00342 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
ACFBBGHA_00343 4.4e-177 ycbJ S Macrolide 2'-phosphotransferase
ACFBBGHA_00344 7e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
ACFBBGHA_00345 2.1e-123 ycbG K FCD
ACFBBGHA_00346 3.6e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ACFBBGHA_00347 1.6e-255 gudP G COG0477 Permeases of the major facilitator superfamily
ACFBBGHA_00348 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ACFBBGHA_00349 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
ACFBBGHA_00350 9e-170 glnL T Regulator
ACFBBGHA_00351 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
ACFBBGHA_00352 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
ACFBBGHA_00353 2.8e-255 agcS E Sodium alanine symporter
ACFBBGHA_00354 2.4e-178 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
ACFBBGHA_00355 4.8e-260 mmuP E amino acid
ACFBBGHA_00356 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
ACFBBGHA_00358 4.9e-128 K UTRA
ACFBBGHA_00359 4.8e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ACFBBGHA_00360 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ACFBBGHA_00361 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ACFBBGHA_00362 8.6e-192 yceA S Belongs to the UPF0176 family
ACFBBGHA_00363 3.2e-46 ybfN
ACFBBGHA_00364 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
ACFBBGHA_00365 2.7e-85 ybfM S SNARE associated Golgi protein
ACFBBGHA_00366 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACFBBGHA_00367 2.1e-168 S Alpha/beta hydrolase family
ACFBBGHA_00369 2e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
ACFBBGHA_00370 2.6e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ACFBBGHA_00371 2.3e-145 msmR K AraC-like ligand binding domain
ACFBBGHA_00372 5.7e-161 ybfH EG EamA-like transporter family
ACFBBGHA_00373 0.0 ybfG M Domain of unknown function (DUF1906)
ACFBBGHA_00375 1.8e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
ACFBBGHA_00376 2e-169 ybfA 3.4.15.5 K FR47-like protein
ACFBBGHA_00377 1.5e-34 S Protein of unknown function (DUF2651)
ACFBBGHA_00378 7.3e-258 glpT G -transporter
ACFBBGHA_00379 4.8e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ACFBBGHA_00380 1.8e-290 ybeC E amino acid
ACFBBGHA_00381 4.9e-41 ybyB
ACFBBGHA_00382 7.8e-246 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
ACFBBGHA_00383 1.9e-22 ybxI 3.5.2.6 V beta-lactamase
ACFBBGHA_00384 1.5e-103 ybxI 3.5.2.6 V beta-lactamase
ACFBBGHA_00385 4.9e-30 ybxH S Family of unknown function (DUF5370)
ACFBBGHA_00386 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
ACFBBGHA_00387 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
ACFBBGHA_00388 4e-215 ybdO S Domain of unknown function (DUF4885)
ACFBBGHA_00389 5.9e-152 ybdN
ACFBBGHA_00390 2.8e-137 KLT Protein tyrosine kinase
ACFBBGHA_00392 1.5e-170 T His Kinase A (phospho-acceptor) domain
ACFBBGHA_00393 1.5e-123 T Transcriptional regulatory protein, C terminal
ACFBBGHA_00394 2e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ACFBBGHA_00395 1.2e-55
ACFBBGHA_00396 2.9e-202 ybcL EGP Major facilitator Superfamily
ACFBBGHA_00397 5.1e-50 ybzH K Helix-turn-helix domain
ACFBBGHA_00398 3.2e-59 ybcI S Uncharacterized conserved protein (DUF2294)
ACFBBGHA_00399 1.9e-46
ACFBBGHA_00400 1.9e-92 can 4.2.1.1 P carbonic anhydrase
ACFBBGHA_00401 0.0 ybcC S Belongs to the UPF0753 family
ACFBBGHA_00402 2.2e-271 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
ACFBBGHA_00403 9.6e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACFBBGHA_00404 4.9e-119 adaA 3.2.2.21 K Transcriptional regulator
ACFBBGHA_00405 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACFBBGHA_00406 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
ACFBBGHA_00407 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACFBBGHA_00408 5.7e-224 ybbR S protein conserved in bacteria
ACFBBGHA_00409 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ACFBBGHA_00410 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
ACFBBGHA_00411 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_00417 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
ACFBBGHA_00418 1.9e-86 ybbJ J acetyltransferase
ACFBBGHA_00419 3e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ACFBBGHA_00420 2.1e-149 ybbH K transcriptional
ACFBBGHA_00421 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ACFBBGHA_00422 2.3e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
ACFBBGHA_00423 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
ACFBBGHA_00424 1.7e-237 ybbC 3.2.1.52 S protein conserved in bacteria
ACFBBGHA_00425 4.2e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
ACFBBGHA_00426 4e-165 feuA P Iron-uptake system-binding protein
ACFBBGHA_00427 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_00428 5.6e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_00429 4.7e-137 ybbA S Putative esterase
ACFBBGHA_00430 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
ACFBBGHA_00432 1.5e-245 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
ACFBBGHA_00433 3.4e-39 S COG NOG14552 non supervised orthologous group
ACFBBGHA_00436 2.1e-38 L Phage integrase, N-terminal SAM-like domain
ACFBBGHA_00438 3.8e-27
ACFBBGHA_00441 3.1e-55 K DNA binding
ACFBBGHA_00442 4.1e-31 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
ACFBBGHA_00443 5.3e-88 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
ACFBBGHA_00444 9e-17
ACFBBGHA_00446 1.2e-28
ACFBBGHA_00448 4.4e-18 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
ACFBBGHA_00449 2.5e-14
ACFBBGHA_00450 1.2e-40
ACFBBGHA_00451 2.9e-145 A Pre-toxin TG
ACFBBGHA_00452 5.2e-39 A Pre-toxin TG
ACFBBGHA_00453 5.7e-25
ACFBBGHA_00454 9.3e-59
ACFBBGHA_00455 2e-08
ACFBBGHA_00462 2e-08
ACFBBGHA_00470 7.8e-08
ACFBBGHA_00478 2e-08
ACFBBGHA_00482 2.7e-143 spo0M S COG4326 Sporulation control protein
ACFBBGHA_00483 3e-27
ACFBBGHA_00484 1.3e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
ACFBBGHA_00485 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACFBBGHA_00486 1.1e-261 ygaK C Berberine and berberine like
ACFBBGHA_00488 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
ACFBBGHA_00489 1.1e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
ACFBBGHA_00490 4.3e-170 ssuA M Sulfonate ABC transporter
ACFBBGHA_00491 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
ACFBBGHA_00492 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
ACFBBGHA_00494 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACFBBGHA_00495 4.1e-78 ygaO
ACFBBGHA_00496 4.4e-29 K Transcriptional regulator
ACFBBGHA_00498 7.9e-114 yhzB S B3/4 domain
ACFBBGHA_00499 7.8e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACFBBGHA_00500 1.1e-175 yhbB S Putative amidase domain
ACFBBGHA_00501 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
ACFBBGHA_00502 1.3e-108 yhbD K Protein of unknown function (DUF4004)
ACFBBGHA_00503 2.7e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
ACFBBGHA_00504 5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
ACFBBGHA_00505 0.0 prkA T Ser protein kinase
ACFBBGHA_00506 2.5e-225 yhbH S Belongs to the UPF0229 family
ACFBBGHA_00507 2.2e-76 yhbI K DNA-binding transcription factor activity
ACFBBGHA_00508 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
ACFBBGHA_00509 3.1e-271 yhcA EGP Major facilitator Superfamily
ACFBBGHA_00510 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
ACFBBGHA_00511 2.8e-37 yhcC
ACFBBGHA_00512 7.8e-55
ACFBBGHA_00513 6.6e-60 yhcF K Transcriptional regulator
ACFBBGHA_00514 1.6e-123 yhcG V ABC transporter, ATP-binding protein
ACFBBGHA_00515 1e-165 yhcH V ABC transporter, ATP-binding protein
ACFBBGHA_00516 8.7e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ACFBBGHA_00517 1e-30 cspB K Cold-shock protein
ACFBBGHA_00518 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
ACFBBGHA_00519 3.4e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
ACFBBGHA_00520 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ACFBBGHA_00521 2.9e-41 yhcM
ACFBBGHA_00522 1.7e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ACFBBGHA_00523 2.8e-166 yhcP
ACFBBGHA_00524 1.5e-99 yhcQ M Spore coat protein
ACFBBGHA_00525 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
ACFBBGHA_00526 1.3e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
ACFBBGHA_00527 1.9e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ACFBBGHA_00528 9.3e-68 yhcU S Family of unknown function (DUF5365)
ACFBBGHA_00529 3.8e-67 yhcV S COG0517 FOG CBS domain
ACFBBGHA_00530 6.6e-119 yhcW 5.4.2.6 S hydrolase
ACFBBGHA_00531 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ACFBBGHA_00532 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACFBBGHA_00533 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ACFBBGHA_00534 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
ACFBBGHA_00535 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACFBBGHA_00536 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACFBBGHA_00537 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
ACFBBGHA_00538 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
ACFBBGHA_00539 2.9e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ACFBBGHA_00540 3.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
ACFBBGHA_00541 1.2e-38 yhdB S YhdB-like protein
ACFBBGHA_00542 2e-52 yhdC S Protein of unknown function (DUF3889)
ACFBBGHA_00543 1.4e-185 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ACFBBGHA_00544 1e-75 nsrR K Transcriptional regulator
ACFBBGHA_00545 7.3e-238 ygxB M Conserved TM helix
ACFBBGHA_00546 2.1e-276 ycgB S Stage V sporulation protein R
ACFBBGHA_00547 5.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
ACFBBGHA_00548 1.8e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ACFBBGHA_00549 3.8e-162 citR K Transcriptional regulator
ACFBBGHA_00550 1.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
ACFBBGHA_00551 7.8e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_00552 3.4e-250 yhdG E amino acid
ACFBBGHA_00553 3.7e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
ACFBBGHA_00554 3.6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ACFBBGHA_00555 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ACFBBGHA_00556 8.1e-45 yhdK S Sigma-M inhibitor protein
ACFBBGHA_00557 6.6e-201 yhdL S Sigma factor regulator N-terminal
ACFBBGHA_00558 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_00559 1.5e-191 yhdN C Aldo keto reductase
ACFBBGHA_00560 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ACFBBGHA_00561 2e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
ACFBBGHA_00562 4.1e-74 cueR K transcriptional
ACFBBGHA_00563 2e-222 yhdR 2.6.1.1 E Aminotransferase
ACFBBGHA_00564 6.6e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
ACFBBGHA_00565 1.3e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACFBBGHA_00566 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACFBBGHA_00567 9.5e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ACFBBGHA_00569 9.9e-184 yhdY M Mechanosensitive ion channel
ACFBBGHA_00570 2.5e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
ACFBBGHA_00571 6e-149 yheN G deacetylase
ACFBBGHA_00572 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
ACFBBGHA_00573 1.8e-224 nhaC C Na H antiporter
ACFBBGHA_00574 1.9e-82 nhaX T Belongs to the universal stress protein A family
ACFBBGHA_00575 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
ACFBBGHA_00576 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
ACFBBGHA_00577 3.7e-111 yheG GM NAD(P)H-binding
ACFBBGHA_00578 6.3e-28 sspB S spore protein
ACFBBGHA_00579 1.3e-36 yheE S Family of unknown function (DUF5342)
ACFBBGHA_00580 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
ACFBBGHA_00581 6.2e-215 yheC HJ YheC/D like ATP-grasp
ACFBBGHA_00582 3.1e-201 yheB S Belongs to the UPF0754 family
ACFBBGHA_00583 9.5e-48 yheA S Belongs to the UPF0342 family
ACFBBGHA_00584 1.5e-205 yhaZ L DNA alkylation repair enzyme
ACFBBGHA_00585 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
ACFBBGHA_00586 2.3e-292 hemZ H coproporphyrinogen III oxidase
ACFBBGHA_00587 4.8e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
ACFBBGHA_00588 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
ACFBBGHA_00590 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
ACFBBGHA_00591 1.1e-26 S YhzD-like protein
ACFBBGHA_00592 4e-167 yhaQ S ABC transporter, ATP-binding protein
ACFBBGHA_00593 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
ACFBBGHA_00594 5.7e-225 yhaO L DNA repair exonuclease
ACFBBGHA_00595 0.0 yhaN L AAA domain
ACFBBGHA_00596 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
ACFBBGHA_00597 1.6e-21 yhaL S Sporulation protein YhaL
ACFBBGHA_00598 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
ACFBBGHA_00599 1.5e-89 yhaK S Putative zincin peptidase
ACFBBGHA_00600 1.3e-54 yhaI S Protein of unknown function (DUF1878)
ACFBBGHA_00601 1e-113 hpr K Negative regulator of protease production and sporulation
ACFBBGHA_00602 7e-39 yhaH S YtxH-like protein
ACFBBGHA_00603 3.6e-80 trpP S Tryptophan transporter TrpP
ACFBBGHA_00604 2.9e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ACFBBGHA_00605 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
ACFBBGHA_00606 4.6e-137 ecsA V transporter (ATP-binding protein)
ACFBBGHA_00607 5.4e-215 ecsB U ABC transporter
ACFBBGHA_00608 3.1e-114 ecsC S EcsC protein family
ACFBBGHA_00609 8.3e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
ACFBBGHA_00610 8.7e-246 yhfA C membrane
ACFBBGHA_00611 1.2e-32 1.15.1.2 C Rubrerythrin
ACFBBGHA_00612 1.1e-89 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
ACFBBGHA_00613 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ACFBBGHA_00614 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACFBBGHA_00615 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
ACFBBGHA_00616 9.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ACFBBGHA_00617 2.4e-101 yhgD K Transcriptional regulator
ACFBBGHA_00618 3.8e-238 yhgE S YhgE Pip N-terminal domain protein
ACFBBGHA_00619 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACFBBGHA_00620 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
ACFBBGHA_00621 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
ACFBBGHA_00622 3.7e-72 3.4.13.21 S ASCH
ACFBBGHA_00623 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
ACFBBGHA_00624 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
ACFBBGHA_00625 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
ACFBBGHA_00626 2.9e-111 yhfK GM NmrA-like family
ACFBBGHA_00627 4.1e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
ACFBBGHA_00628 7.4e-65 yhfM
ACFBBGHA_00629 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
ACFBBGHA_00630 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
ACFBBGHA_00631 1.4e-75 VY92_01935 K acetyltransferase
ACFBBGHA_00632 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
ACFBBGHA_00633 1.6e-158 yfmC M Periplasmic binding protein
ACFBBGHA_00634 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
ACFBBGHA_00635 1.4e-195 vraB 2.3.1.9 I Belongs to the thiolase family
ACFBBGHA_00636 1.8e-270 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
ACFBBGHA_00637 1.9e-90 bioY S BioY family
ACFBBGHA_00638 1.7e-182 hemAT NT chemotaxis protein
ACFBBGHA_00639 2.3e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
ACFBBGHA_00640 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_00641 1.3e-32 yhzC S IDEAL
ACFBBGHA_00642 4.2e-109 comK K Competence transcription factor
ACFBBGHA_00643 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
ACFBBGHA_00644 7.8e-42 yhjA S Excalibur calcium-binding domain
ACFBBGHA_00645 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACFBBGHA_00646 6.9e-27 yhjC S Protein of unknown function (DUF3311)
ACFBBGHA_00647 6.7e-60 yhjD
ACFBBGHA_00648 9.1e-110 yhjE S SNARE associated Golgi protein
ACFBBGHA_00649 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
ACFBBGHA_00650 2.1e-282 yhjG CH FAD binding domain
ACFBBGHA_00651 6.5e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
ACFBBGHA_00652 4.5e-214 glcP G Major Facilitator Superfamily
ACFBBGHA_00653 4.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
ACFBBGHA_00654 5.8e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
ACFBBGHA_00655 1.4e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
ACFBBGHA_00656 5.9e-188 yhjM 5.1.1.1 K Transcriptional regulator
ACFBBGHA_00657 1.9e-201 abrB S membrane
ACFBBGHA_00658 4.2e-212 EGP Transmembrane secretion effector
ACFBBGHA_00659 0.0 S Sugar transport-related sRNA regulator N-term
ACFBBGHA_00660 9.5e-34 yhjQ C COG1145 Ferredoxin
ACFBBGHA_00661 2.2e-78 yhjR S Rubrerythrin
ACFBBGHA_00662 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
ACFBBGHA_00663 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
ACFBBGHA_00664 3.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
ACFBBGHA_00665 0.0 sbcC L COG0419 ATPase involved in DNA repair
ACFBBGHA_00666 1.1e-49 yisB V COG1403 Restriction endonuclease
ACFBBGHA_00667 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
ACFBBGHA_00668 3e-66 gerPE S Spore germination protein GerPE
ACFBBGHA_00669 6.3e-24 gerPD S Spore germination protein
ACFBBGHA_00670 5.3e-54 gerPC S Spore germination protein
ACFBBGHA_00671 4e-34 gerPB S cell differentiation
ACFBBGHA_00672 1.9e-33 gerPA S Spore germination protein
ACFBBGHA_00673 1.5e-22 yisI S Spo0E like sporulation regulatory protein
ACFBBGHA_00674 1e-173 cotH M Spore Coat
ACFBBGHA_00675 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
ACFBBGHA_00676 3e-57 yisL S UPF0344 protein
ACFBBGHA_00677 0.0 wprA O Belongs to the peptidase S8 family
ACFBBGHA_00678 3.6e-102 yisN S Protein of unknown function (DUF2777)
ACFBBGHA_00679 0.0 asnO 6.3.5.4 E Asparagine synthase
ACFBBGHA_00680 4.7e-88 yizA S Damage-inducible protein DinB
ACFBBGHA_00681 2.4e-147 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
ACFBBGHA_00682 4e-243 yisQ V Mate efflux family protein
ACFBBGHA_00683 4.5e-160 yisR K Transcriptional regulator
ACFBBGHA_00684 2.4e-184 purR K helix_turn _helix lactose operon repressor
ACFBBGHA_00685 4.8e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
ACFBBGHA_00686 7e-92 yisT S DinB family
ACFBBGHA_00687 1.4e-99 argO S Lysine exporter protein LysE YggA
ACFBBGHA_00688 4e-270 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
ACFBBGHA_00689 4e-36 mcbG S Pentapeptide repeats (9 copies)
ACFBBGHA_00690 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ACFBBGHA_00691 1.9e-112 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
ACFBBGHA_00692 2.7e-232 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
ACFBBGHA_00693 2.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
ACFBBGHA_00694 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
ACFBBGHA_00695 1.9e-141 yitD 4.4.1.19 S synthase
ACFBBGHA_00696 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACFBBGHA_00697 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ACFBBGHA_00698 1.5e-228 yitG EGP Major facilitator Superfamily
ACFBBGHA_00699 2.4e-153 yitH K Acetyltransferase (GNAT) domain
ACFBBGHA_00700 4.6e-71 yjcF S Acetyltransferase (GNAT) domain
ACFBBGHA_00701 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
ACFBBGHA_00702 8.6e-55 yajQ S Belongs to the UPF0234 family
ACFBBGHA_00703 1.3e-159 cvfB S protein conserved in bacteria
ACFBBGHA_00704 8.5e-94
ACFBBGHA_00705 4e-170
ACFBBGHA_00706 2.2e-96 S Sporulation delaying protein SdpA
ACFBBGHA_00707 1.5e-58 K Transcriptional regulator PadR-like family
ACFBBGHA_00708 1.3e-94
ACFBBGHA_00709 1.4e-44 yitR S Domain of unknown function (DUF3784)
ACFBBGHA_00710 1.6e-307 nprB 3.4.24.28 E Peptidase M4
ACFBBGHA_00711 8.4e-159 yitS S protein conserved in bacteria
ACFBBGHA_00712 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
ACFBBGHA_00713 3.8e-73 ipi S Intracellular proteinase inhibitor
ACFBBGHA_00714 1.2e-17 S Protein of unknown function (DUF3813)
ACFBBGHA_00716 2.1e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
ACFBBGHA_00717 1.4e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
ACFBBGHA_00718 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
ACFBBGHA_00719 1.5e-22 pilT S Proteolipid membrane potential modulator
ACFBBGHA_00720 3.5e-266 yitY C D-arabinono-1,4-lactone oxidase
ACFBBGHA_00721 3.2e-87 norB G Major Facilitator Superfamily
ACFBBGHA_00722 9.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACFBBGHA_00723 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACFBBGHA_00724 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
ACFBBGHA_00725 1.3e-218 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
ACFBBGHA_00726 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ACFBBGHA_00727 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
ACFBBGHA_00728 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACFBBGHA_00729 9.5e-28 yjzC S YjzC-like protein
ACFBBGHA_00730 2.3e-16 yjzD S Protein of unknown function (DUF2929)
ACFBBGHA_00731 1.1e-141 yjaU I carboxylic ester hydrolase activity
ACFBBGHA_00732 6.9e-101 yjaV
ACFBBGHA_00733 2.5e-183 med S Transcriptional activator protein med
ACFBBGHA_00734 7.3e-26 comZ S ComZ
ACFBBGHA_00735 2.4e-20 yjzB
ACFBBGHA_00736 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACFBBGHA_00737 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ACFBBGHA_00738 3.3e-149 yjaZ O Zn-dependent protease
ACFBBGHA_00739 1.8e-184 appD P Belongs to the ABC transporter superfamily
ACFBBGHA_00740 2.3e-184 appF E Belongs to the ABC transporter superfamily
ACFBBGHA_00741 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
ACFBBGHA_00742 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACFBBGHA_00743 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACFBBGHA_00744 5e-147 yjbA S Belongs to the UPF0736 family
ACFBBGHA_00745 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
ACFBBGHA_00746 0.0 oppA E ABC transporter substrate-binding protein
ACFBBGHA_00747 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACFBBGHA_00748 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACFBBGHA_00749 1.5e-197 oppD P Belongs to the ABC transporter superfamily
ACFBBGHA_00750 1.2e-171 oppF E Belongs to the ABC transporter superfamily
ACFBBGHA_00751 4.9e-205 yjbB EGP Major Facilitator Superfamily
ACFBBGHA_00752 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ACFBBGHA_00753 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
ACFBBGHA_00754 6e-112 yjbE P Integral membrane protein TerC family
ACFBBGHA_00755 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
ACFBBGHA_00756 4.7e-221 yjbF S Competence protein
ACFBBGHA_00757 0.0 pepF E oligoendopeptidase F
ACFBBGHA_00758 1.8e-20
ACFBBGHA_00760 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
ACFBBGHA_00761 3.7e-72 yjbI S Bacterial-like globin
ACFBBGHA_00762 7e-85 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ACFBBGHA_00763 1.2e-100 yjbK S protein conserved in bacteria
ACFBBGHA_00764 7.1e-62 yjbL S Belongs to the UPF0738 family
ACFBBGHA_00765 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
ACFBBGHA_00766 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACFBBGHA_00767 1.2e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ACFBBGHA_00768 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
ACFBBGHA_00769 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
ACFBBGHA_00770 4.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACFBBGHA_00771 1.2e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
ACFBBGHA_00772 2.2e-215 thiO 1.4.3.19 E Glycine oxidase
ACFBBGHA_00773 6.7e-30 thiS H thiamine diphosphate biosynthetic process
ACFBBGHA_00774 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
ACFBBGHA_00775 1.9e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
ACFBBGHA_00776 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ACFBBGHA_00777 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
ACFBBGHA_00778 6.5e-53 yjbX S Spore coat protein
ACFBBGHA_00779 4.4e-82 cotZ S Spore coat protein
ACFBBGHA_00780 7.6e-96 cotY S Spore coat protein Z
ACFBBGHA_00781 1.2e-67 cotX S Spore Coat Protein X and V domain
ACFBBGHA_00782 7.4e-23 cotW
ACFBBGHA_00783 3.2e-49 cotV S Spore Coat Protein X and V domain
ACFBBGHA_00784 5.6e-56 yjcA S Protein of unknown function (DUF1360)
ACFBBGHA_00787 2.9e-38 spoVIF S Stage VI sporulation protein F
ACFBBGHA_00788 0.0 yjcD 3.6.4.12 L DNA helicase
ACFBBGHA_00789 3.2e-37
ACFBBGHA_00790 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ACFBBGHA_00791 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
ACFBBGHA_00792 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
ACFBBGHA_00793 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ACFBBGHA_00794 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ACFBBGHA_00795 2.9e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
ACFBBGHA_00796 5.4e-212 yjcL S Protein of unknown function (DUF819)
ACFBBGHA_00798 5.4e-32
ACFBBGHA_00799 1.9e-30
ACFBBGHA_00800 6e-250 M nucleic acid phosphodiester bond hydrolysis
ACFBBGHA_00801 8.3e-21
ACFBBGHA_00804 2.2e-127 S response regulator aspartate phosphatase
ACFBBGHA_00805 4.2e-46 yjcS S Antibiotic biosynthesis monooxygenase
ACFBBGHA_00806 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
ACFBBGHA_00808 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
ACFBBGHA_00809 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
ACFBBGHA_00810 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
ACFBBGHA_00811 5.9e-49 yjdF S Protein of unknown function (DUF2992)
ACFBBGHA_00812 5.9e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
ACFBBGHA_00814 2.3e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACFBBGHA_00815 9.9e-29 S Domain of unknown function (DUF4177)
ACFBBGHA_00816 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
ACFBBGHA_00817 3.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ACFBBGHA_00819 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
ACFBBGHA_00820 5.5e-83 S Protein of unknown function (DUF2690)
ACFBBGHA_00821 2.3e-20 yjfB S Putative motility protein
ACFBBGHA_00822 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
ACFBBGHA_00823 1.2e-45 T PhoQ Sensor
ACFBBGHA_00824 5.8e-103 yjgB S Domain of unknown function (DUF4309)
ACFBBGHA_00825 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
ACFBBGHA_00826 3.7e-94 yjgD S Protein of unknown function (DUF1641)
ACFBBGHA_00827 8.7e-07 S Domain of unknown function (DUF4352)
ACFBBGHA_00828 1.3e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
ACFBBGHA_00830 3e-223 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
ACFBBGHA_00831 2.2e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
ACFBBGHA_00832 8.2e-30
ACFBBGHA_00833 4.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
ACFBBGHA_00834 9.5e-122 ybbM S transport system, permease component
ACFBBGHA_00835 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
ACFBBGHA_00836 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
ACFBBGHA_00837 2e-91 yjlB S Cupin domain
ACFBBGHA_00838 7.1e-66 yjlC S Protein of unknown function (DUF1641)
ACFBBGHA_00839 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
ACFBBGHA_00840 3e-278 uxaC 5.3.1.12 G glucuronate isomerase
ACFBBGHA_00841 1.4e-248 yjmB G symporter YjmB
ACFBBGHA_00842 1.9e-186 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
ACFBBGHA_00843 1.4e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
ACFBBGHA_00844 8.9e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
ACFBBGHA_00845 6.8e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_00846 3.7e-227 exuT G Sugar (and other) transporter
ACFBBGHA_00847 1.5e-183 exuR K transcriptional
ACFBBGHA_00848 4.9e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
ACFBBGHA_00849 4.4e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
ACFBBGHA_00850 4.3e-130 MA20_18170 S membrane transporter protein
ACFBBGHA_00851 9.5e-80 yjoA S DinB family
ACFBBGHA_00852 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
ACFBBGHA_00853 2.1e-213 S response regulator aspartate phosphatase
ACFBBGHA_00855 6.3e-41 S YCII-related domain
ACFBBGHA_00856 5.4e-162 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
ACFBBGHA_00857 6.1e-61 yjqA S Bacterial PH domain
ACFBBGHA_00858 2.1e-111 yjqB S Pfam:DUF867
ACFBBGHA_00859 4.4e-160 ydbD P Catalase
ACFBBGHA_00860 2.3e-110 xkdA E IrrE N-terminal-like domain
ACFBBGHA_00861 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
ACFBBGHA_00863 2.3e-156 xkdB K sequence-specific DNA binding
ACFBBGHA_00864 4.1e-118 xkdC L Bacterial dnaA protein
ACFBBGHA_00867 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
ACFBBGHA_00868 4.1e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
ACFBBGHA_00869 5.3e-139 xtmA L phage terminase small subunit
ACFBBGHA_00870 6.9e-253 xtmB S phage terminase, large subunit
ACFBBGHA_00871 4.6e-285 yqbA S portal protein
ACFBBGHA_00872 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
ACFBBGHA_00873 5.8e-169 xkdG S Phage capsid family
ACFBBGHA_00874 6.2e-61 yqbG S Protein of unknown function (DUF3199)
ACFBBGHA_00875 1.2e-63 yqbH S Domain of unknown function (DUF3599)
ACFBBGHA_00876 1.1e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
ACFBBGHA_00877 6.7e-75 xkdJ
ACFBBGHA_00878 2.5e-256 xkdK S Phage tail sheath C-terminal domain
ACFBBGHA_00879 6.1e-76 xkdM S Phage tail tube protein
ACFBBGHA_00880 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
ACFBBGHA_00881 0.0 xkdO L Transglycosylase SLT domain
ACFBBGHA_00882 9.2e-121 xkdP S Lysin motif
ACFBBGHA_00883 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
ACFBBGHA_00884 2.1e-39 xkdR S Protein of unknown function (DUF2577)
ACFBBGHA_00885 3.4e-68 xkdS S Protein of unknown function (DUF2634)
ACFBBGHA_00886 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
ACFBBGHA_00887 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
ACFBBGHA_00888 1.5e-40
ACFBBGHA_00889 0.0
ACFBBGHA_00890 9.1e-45 xkdW S XkdW protein
ACFBBGHA_00891 4.2e-22 xkdX
ACFBBGHA_00892 9.9e-152 xepA
ACFBBGHA_00893 2.8e-39 xhlA S Haemolysin XhlA
ACFBBGHA_00894 1.3e-38 xhlB S SPP1 phage holin
ACFBBGHA_00895 3.8e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ACFBBGHA_00897 6.7e-23 spoIISB S Stage II sporulation protein SB
ACFBBGHA_00898 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
ACFBBGHA_00899 5.8e-175 pit P phosphate transporter
ACFBBGHA_00900 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
ACFBBGHA_00901 2.3e-240 steT E amino acid
ACFBBGHA_00902 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
ACFBBGHA_00903 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACFBBGHA_00904 1.9e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ACFBBGHA_00906 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACFBBGHA_00907 1.4e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
ACFBBGHA_00908 7.4e-152 dppA E D-aminopeptidase
ACFBBGHA_00909 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACFBBGHA_00910 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACFBBGHA_00911 2.8e-185 dppD P Belongs to the ABC transporter superfamily
ACFBBGHA_00912 0.0 dppE E ABC transporter substrate-binding protein
ACFBBGHA_00914 1.1e-175 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
ACFBBGHA_00915 8.8e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
ACFBBGHA_00916 2e-166 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
ACFBBGHA_00917 5.5e-186 ykfD E Belongs to the ABC transporter superfamily
ACFBBGHA_00918 1.8e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
ACFBBGHA_00919 2e-160 ykgA E Amidinotransferase
ACFBBGHA_00920 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
ACFBBGHA_00921 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACFBBGHA_00922 7.2e-09
ACFBBGHA_00923 2.7e-129 ykjA S Protein of unknown function (DUF421)
ACFBBGHA_00924 3.9e-98 ykkA S Protein of unknown function (DUF664)
ACFBBGHA_00925 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ACFBBGHA_00926 3.5e-55 ykkC P Multidrug resistance protein
ACFBBGHA_00927 7e-50 ykkD P Multidrug resistance protein
ACFBBGHA_00928 1.1e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
ACFBBGHA_00929 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACFBBGHA_00930 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACFBBGHA_00931 1.3e-70 ohrA O Organic hydroperoxide resistance protein
ACFBBGHA_00932 4.4e-74 ohrR K COG1846 Transcriptional regulators
ACFBBGHA_00933 1.9e-71 ohrB O Organic hydroperoxide resistance protein
ACFBBGHA_00934 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
ACFBBGHA_00935 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ACFBBGHA_00936 5e-176 isp O Belongs to the peptidase S8 family
ACFBBGHA_00937 1.8e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ACFBBGHA_00938 5.3e-136 ykoC P Cobalt transport protein
ACFBBGHA_00939 4.2e-308 P ABC transporter, ATP-binding protein
ACFBBGHA_00940 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
ACFBBGHA_00941 1.1e-109 ykoF S YKOF-related Family
ACFBBGHA_00942 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_00943 2.8e-241 ykoH 2.7.13.3 T Histidine kinase
ACFBBGHA_00944 2.1e-112 ykoI S Peptidase propeptide and YPEB domain
ACFBBGHA_00945 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
ACFBBGHA_00948 2.2e-222 mgtE P Acts as a magnesium transporter
ACFBBGHA_00949 1.4e-53 tnrA K transcriptional
ACFBBGHA_00950 5.9e-18
ACFBBGHA_00951 6.9e-26 ykoL
ACFBBGHA_00952 1.3e-81 mhqR K transcriptional
ACFBBGHA_00953 5e-212 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
ACFBBGHA_00954 1.1e-98 ykoP G polysaccharide deacetylase
ACFBBGHA_00955 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
ACFBBGHA_00956 0.0 ykoS
ACFBBGHA_00957 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ACFBBGHA_00958 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
ACFBBGHA_00959 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
ACFBBGHA_00960 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
ACFBBGHA_00961 5.4e-110 ykoX S membrane-associated protein
ACFBBGHA_00962 8.7e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
ACFBBGHA_00963 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACFBBGHA_00964 1.2e-112 rsgI S Anti-sigma factor N-terminus
ACFBBGHA_00965 1.9e-26 sspD S small acid-soluble spore protein
ACFBBGHA_00966 1.9e-124 ykrK S Domain of unknown function (DUF1836)
ACFBBGHA_00967 1.7e-154 htpX O Belongs to the peptidase M48B family
ACFBBGHA_00968 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
ACFBBGHA_00969 1.2e-10 ydfR S Protein of unknown function (DUF421)
ACFBBGHA_00970 4.1e-18 ykzE
ACFBBGHA_00971 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
ACFBBGHA_00972 0.0 kinE 2.7.13.3 T Histidine kinase
ACFBBGHA_00973 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACFBBGHA_00975 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACFBBGHA_00976 1.2e-227 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ACFBBGHA_00977 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
ACFBBGHA_00978 9.8e-230 mtnE 2.6.1.83 E Aminotransferase
ACFBBGHA_00979 1.3e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
ACFBBGHA_00980 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ACFBBGHA_00981 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
ACFBBGHA_00982 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACFBBGHA_00983 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
ACFBBGHA_00984 7.5e-10 S Spo0E like sporulation regulatory protein
ACFBBGHA_00985 2.6e-63 eag
ACFBBGHA_00986 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
ACFBBGHA_00987 1.3e-75 ykvE K transcriptional
ACFBBGHA_00988 2.5e-125 motB N Flagellar motor protein
ACFBBGHA_00989 1e-137 motA N flagellar motor
ACFBBGHA_00990 0.0 clpE O Belongs to the ClpA ClpB family
ACFBBGHA_00991 1.8e-179 ykvI S membrane
ACFBBGHA_00992 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACFBBGHA_00993 1.4e-80 queD 4.1.2.50, 4.2.3.12 H synthase
ACFBBGHA_00994 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
ACFBBGHA_00995 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACFBBGHA_00996 9.3e-59 ykvN K HxlR-like helix-turn-helix
ACFBBGHA_00997 2.9e-131 IQ Enoyl-(Acyl carrier protein) reductase
ACFBBGHA_00998 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
ACFBBGHA_00999 1.1e-31 3.5.1.104 M LysM domain
ACFBBGHA_01000 6.9e-162 G Glycosyl hydrolases family 18
ACFBBGHA_01001 2.8e-45 ykvR S Protein of unknown function (DUF3219)
ACFBBGHA_01002 6e-25 ykvS S protein conserved in bacteria
ACFBBGHA_01003 2.8e-28
ACFBBGHA_01004 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
ACFBBGHA_01005 2.9e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ACFBBGHA_01006 3.5e-88 stoA CO thiol-disulfide
ACFBBGHA_01007 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
ACFBBGHA_01008 1e-09
ACFBBGHA_01009 4.8e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
ACFBBGHA_01010 9.2e-178 ykvZ 5.1.1.1 K Transcriptional regulator
ACFBBGHA_01012 7.6e-128 glcT K antiterminator
ACFBBGHA_01013 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ACFBBGHA_01014 2.1e-39 ptsH G phosphocarrier protein HPr
ACFBBGHA_01015 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACFBBGHA_01016 7.2e-39 splA S Transcriptional regulator
ACFBBGHA_01017 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
ACFBBGHA_01018 2e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ACFBBGHA_01019 1.7e-258 mcpC NT chemotaxis protein
ACFBBGHA_01020 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
ACFBBGHA_01021 8e-124 ykwD J protein with SCP PR1 domains
ACFBBGHA_01022 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
ACFBBGHA_01023 0.0 pilS 2.7.13.3 T Histidine kinase
ACFBBGHA_01024 8.8e-223 patA 2.6.1.1 E Aminotransferase
ACFBBGHA_01025 2.2e-15
ACFBBGHA_01026 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
ACFBBGHA_01027 1.7e-84 ykyB S YkyB-like protein
ACFBBGHA_01028 5.1e-232 ykuC EGP Major facilitator Superfamily
ACFBBGHA_01029 1.8e-87 ykuD S protein conserved in bacteria
ACFBBGHA_01030 2.1e-165 ykuE S Metallophosphoesterase
ACFBBGHA_01031 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_01032 6.7e-234 ykuI T Diguanylate phosphodiesterase
ACFBBGHA_01033 3.9e-37 ykuJ S protein conserved in bacteria
ACFBBGHA_01034 4.4e-94 ykuK S Ribonuclease H-like
ACFBBGHA_01035 3.9e-27 ykzF S Antirepressor AbbA
ACFBBGHA_01036 1.6e-76 ykuL S CBS domain
ACFBBGHA_01037 3.5e-168 ccpC K Transcriptional regulator
ACFBBGHA_01038 2.9e-84 fld C Flavodoxin domain
ACFBBGHA_01039 2.6e-174 ykuO
ACFBBGHA_01040 1.8e-78 fld C Flavodoxin
ACFBBGHA_01041 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
ACFBBGHA_01042 2.4e-214 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
ACFBBGHA_01043 9e-37 ykuS S Belongs to the UPF0180 family
ACFBBGHA_01044 1.5e-141 ykuT M Mechanosensitive ion channel
ACFBBGHA_01045 3.9e-101 ykuU O Alkyl hydroperoxide reductase
ACFBBGHA_01046 6.3e-81 ykuV CO thiol-disulfide
ACFBBGHA_01047 5.8e-95 rok K Repressor of ComK
ACFBBGHA_01048 7.9e-145 yknT
ACFBBGHA_01049 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
ACFBBGHA_01050 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
ACFBBGHA_01051 1.2e-244 moeA 2.10.1.1 H molybdopterin
ACFBBGHA_01052 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
ACFBBGHA_01053 2.7e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
ACFBBGHA_01054 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ACFBBGHA_01055 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
ACFBBGHA_01056 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
ACFBBGHA_01057 1.9e-116 yknW S Yip1 domain
ACFBBGHA_01058 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACFBBGHA_01059 2.5e-124 macB V ABC transporter, ATP-binding protein
ACFBBGHA_01060 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
ACFBBGHA_01061 3.1e-136 fruR K Transcriptional regulator
ACFBBGHA_01062 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
ACFBBGHA_01063 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
ACFBBGHA_01064 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ACFBBGHA_01065 8.1e-39 ykoA
ACFBBGHA_01066 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ACFBBGHA_01067 2.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACFBBGHA_01068 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
ACFBBGHA_01069 1.1e-12 S Uncharacterized protein YkpC
ACFBBGHA_01070 7.7e-183 mreB D Rod-share determining protein MreBH
ACFBBGHA_01071 1.5e-43 abrB K of stationary sporulation gene expression
ACFBBGHA_01072 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
ACFBBGHA_01073 1.3e-156 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
ACFBBGHA_01074 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
ACFBBGHA_01075 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACFBBGHA_01076 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACFBBGHA_01077 8.2e-31 ykzG S Belongs to the UPF0356 family
ACFBBGHA_01078 1.6e-146 ykrA S hydrolases of the HAD superfamily
ACFBBGHA_01079 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ACFBBGHA_01081 2e-115 recN L Putative cell-wall binding lipoprotein
ACFBBGHA_01082 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ACFBBGHA_01083 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ACFBBGHA_01084 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ACFBBGHA_01085 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ACFBBGHA_01086 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
ACFBBGHA_01087 1e-276 speA 4.1.1.19 E Arginine
ACFBBGHA_01088 1e-41 yktA S Belongs to the UPF0223 family
ACFBBGHA_01089 2.1e-117 yktB S Belongs to the UPF0637 family
ACFBBGHA_01090 7.1e-26 ykzI
ACFBBGHA_01091 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
ACFBBGHA_01092 3.4e-77 ykzC S Acetyltransferase (GNAT) family
ACFBBGHA_01093 9.3e-172 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACFBBGHA_01094 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
ACFBBGHA_01095 0.0 ylaA
ACFBBGHA_01096 2.7e-42 ylaB
ACFBBGHA_01097 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_01098 7e-12 sigC S Putative zinc-finger
ACFBBGHA_01099 2.6e-37 ylaE
ACFBBGHA_01100 8.2e-22 S Family of unknown function (DUF5325)
ACFBBGHA_01101 0.0 typA T GTP-binding protein TypA
ACFBBGHA_01102 4.2e-47 ylaH S YlaH-like protein
ACFBBGHA_01103 2.5e-32 ylaI S protein conserved in bacteria
ACFBBGHA_01104 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ACFBBGHA_01105 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
ACFBBGHA_01106 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACFBBGHA_01107 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
ACFBBGHA_01108 8.7e-44 ylaN S Belongs to the UPF0358 family
ACFBBGHA_01109 3.2e-212 ftsW D Belongs to the SEDS family
ACFBBGHA_01110 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ACFBBGHA_01111 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
ACFBBGHA_01112 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
ACFBBGHA_01113 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
ACFBBGHA_01114 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACFBBGHA_01115 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
ACFBBGHA_01116 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
ACFBBGHA_01117 2.8e-165 ctaG S cytochrome c oxidase
ACFBBGHA_01118 7e-62 ylbA S YugN-like family
ACFBBGHA_01119 2.6e-74 ylbB T COG0517 FOG CBS domain
ACFBBGHA_01120 9.6e-200 ylbC S protein with SCP PR1 domains
ACFBBGHA_01121 4.1e-63 ylbD S Putative coat protein
ACFBBGHA_01122 6.7e-37 ylbE S YlbE-like protein
ACFBBGHA_01123 1.8e-75 ylbF S Belongs to the UPF0342 family
ACFBBGHA_01124 3.7e-38 ylbG S UPF0298 protein
ACFBBGHA_01125 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
ACFBBGHA_01126 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACFBBGHA_01127 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
ACFBBGHA_01128 1.3e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
ACFBBGHA_01129 6.8e-187 ylbL T Belongs to the peptidase S16 family
ACFBBGHA_01130 8.4e-232 ylbM S Belongs to the UPF0348 family
ACFBBGHA_01132 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
ACFBBGHA_01133 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
ACFBBGHA_01134 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
ACFBBGHA_01135 1.5e-88 ylbP K n-acetyltransferase
ACFBBGHA_01136 3.4e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACFBBGHA_01137 4.6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ACFBBGHA_01138 2.9e-78 mraZ K Belongs to the MraZ family
ACFBBGHA_01139 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
ACFBBGHA_01140 3.7e-44 ftsL D Essential cell division protein
ACFBBGHA_01141 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
ACFBBGHA_01142 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
ACFBBGHA_01143 8.9e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACFBBGHA_01144 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACFBBGHA_01145 2.2e-254 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACFBBGHA_01146 5.7e-186 spoVE D Belongs to the SEDS family
ACFBBGHA_01147 2.8e-199 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACFBBGHA_01148 5.3e-167 murB 1.3.1.98 M cell wall formation
ACFBBGHA_01149 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
ACFBBGHA_01150 2.4e-103 ylxW S protein conserved in bacteria
ACFBBGHA_01151 1e-102 ylxX S protein conserved in bacteria
ACFBBGHA_01152 6.2e-58 sbp S small basic protein
ACFBBGHA_01153 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
ACFBBGHA_01154 2.9e-202 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACFBBGHA_01155 0.0 bpr O COG1404 Subtilisin-like serine proteases
ACFBBGHA_01156 4.8e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
ACFBBGHA_01157 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACFBBGHA_01158 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACFBBGHA_01159 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
ACFBBGHA_01160 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
ACFBBGHA_01161 9e-37 ylmC S sporulation protein
ACFBBGHA_01162 1.6e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
ACFBBGHA_01163 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACFBBGHA_01164 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
ACFBBGHA_01165 1.3e-39 yggT S membrane
ACFBBGHA_01166 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
ACFBBGHA_01167 2.6e-67 divIVA D Cell division initiation protein
ACFBBGHA_01168 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACFBBGHA_01169 3.8e-63 dksA T COG1734 DnaK suppressor protein
ACFBBGHA_01170 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACFBBGHA_01171 2.5e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
ACFBBGHA_01172 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACFBBGHA_01173 2.6e-231 pyrP F Xanthine uracil
ACFBBGHA_01174 2.1e-163 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
ACFBBGHA_01175 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
ACFBBGHA_01176 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
ACFBBGHA_01177 0.0 carB 6.3.5.5 F Belongs to the CarB family
ACFBBGHA_01178 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
ACFBBGHA_01179 1.7e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
ACFBBGHA_01180 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
ACFBBGHA_01181 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACFBBGHA_01183 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
ACFBBGHA_01184 1.4e-179 cysP P phosphate transporter
ACFBBGHA_01185 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
ACFBBGHA_01186 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
ACFBBGHA_01187 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
ACFBBGHA_01188 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
ACFBBGHA_01189 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
ACFBBGHA_01190 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
ACFBBGHA_01191 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
ACFBBGHA_01192 3.1e-156 yloC S stress-induced protein
ACFBBGHA_01193 1.5e-40 ylzA S Belongs to the UPF0296 family
ACFBBGHA_01194 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
ACFBBGHA_01195 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
ACFBBGHA_01196 1.2e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACFBBGHA_01197 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACFBBGHA_01198 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
ACFBBGHA_01199 1.1e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACFBBGHA_01200 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACFBBGHA_01201 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ACFBBGHA_01202 1.6e-140 stp 3.1.3.16 T phosphatase
ACFBBGHA_01203 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
ACFBBGHA_01204 1.9e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
ACFBBGHA_01205 8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
ACFBBGHA_01206 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
ACFBBGHA_01207 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
ACFBBGHA_01208 5.5e-59 asp S protein conserved in bacteria
ACFBBGHA_01209 5.6e-300 yloV S kinase related to dihydroxyacetone kinase
ACFBBGHA_01210 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
ACFBBGHA_01211 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
ACFBBGHA_01212 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACFBBGHA_01213 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
ACFBBGHA_01214 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
ACFBBGHA_01215 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ACFBBGHA_01216 6.1e-129 IQ reductase
ACFBBGHA_01217 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACFBBGHA_01218 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
ACFBBGHA_01219 0.0 smc D Required for chromosome condensation and partitioning
ACFBBGHA_01220 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ACFBBGHA_01221 1.1e-86
ACFBBGHA_01222 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
ACFBBGHA_01223 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACFBBGHA_01224 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
ACFBBGHA_01225 4.5e-36 ylqC S Belongs to the UPF0109 family
ACFBBGHA_01226 1.4e-60 ylqD S YlqD protein
ACFBBGHA_01227 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACFBBGHA_01228 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
ACFBBGHA_01229 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
ACFBBGHA_01230 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ACFBBGHA_01231 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACFBBGHA_01232 1e-288 ylqG
ACFBBGHA_01233 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
ACFBBGHA_01234 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
ACFBBGHA_01235 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACFBBGHA_01236 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
ACFBBGHA_01237 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACFBBGHA_01238 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ACFBBGHA_01239 2.5e-169 xerC L tyrosine recombinase XerC
ACFBBGHA_01240 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACFBBGHA_01241 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACFBBGHA_01242 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ACFBBGHA_01243 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
ACFBBGHA_01244 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
ACFBBGHA_01245 1.9e-31 fliE N Flagellar hook-basal body
ACFBBGHA_01246 2.4e-255 fliF N The M ring may be actively involved in energy transduction
ACFBBGHA_01247 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
ACFBBGHA_01248 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
ACFBBGHA_01249 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
ACFBBGHA_01250 3.2e-69 fliJ N Flagellar biosynthesis chaperone
ACFBBGHA_01251 1.3e-36 ylxF S MgtE intracellular N domain
ACFBBGHA_01252 2e-216 fliK N Flagellar hook-length control protein
ACFBBGHA_01253 1.7e-72 flgD N Flagellar basal body rod modification protein
ACFBBGHA_01254 8.2e-140 flgG N Flagellar basal body rod
ACFBBGHA_01255 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
ACFBBGHA_01256 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
ACFBBGHA_01257 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACFBBGHA_01258 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
ACFBBGHA_01259 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
ACFBBGHA_01260 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
ACFBBGHA_01261 2.2e-36 fliQ N Role in flagellar biosynthesis
ACFBBGHA_01262 3.6e-132 fliR N Flagellar biosynthetic protein FliR
ACFBBGHA_01263 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACFBBGHA_01264 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACFBBGHA_01265 5.7e-200 flhF N Flagellar biosynthesis regulator FlhF
ACFBBGHA_01266 7.5e-158 flhG D Belongs to the ParA family
ACFBBGHA_01267 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
ACFBBGHA_01268 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
ACFBBGHA_01269 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
ACFBBGHA_01270 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
ACFBBGHA_01271 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
ACFBBGHA_01272 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACFBBGHA_01273 1.8e-76 ylxL
ACFBBGHA_01274 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
ACFBBGHA_01275 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACFBBGHA_01276 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
ACFBBGHA_01277 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
ACFBBGHA_01278 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACFBBGHA_01279 1.6e-138 cdsA 2.7.7.41 S Belongs to the CDS family
ACFBBGHA_01280 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
ACFBBGHA_01281 7.7e-233 rasP M zinc metalloprotease
ACFBBGHA_01282 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
ACFBBGHA_01283 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACFBBGHA_01284 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
ACFBBGHA_01285 1.1e-203 nusA K Participates in both transcription termination and antitermination
ACFBBGHA_01286 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
ACFBBGHA_01287 3.1e-47 ylxQ J ribosomal protein
ACFBBGHA_01288 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACFBBGHA_01289 3.9e-44 ylxP S protein conserved in bacteria
ACFBBGHA_01290 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACFBBGHA_01291 1.8e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACFBBGHA_01292 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
ACFBBGHA_01293 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACFBBGHA_01294 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
ACFBBGHA_01295 1.1e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
ACFBBGHA_01296 4.4e-233 pepR S Belongs to the peptidase M16 family
ACFBBGHA_01297 2.6e-42 ymxH S YlmC YmxH family
ACFBBGHA_01298 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
ACFBBGHA_01299 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
ACFBBGHA_01300 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACFBBGHA_01301 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
ACFBBGHA_01302 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACFBBGHA_01303 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACFBBGHA_01304 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
ACFBBGHA_01305 4.4e-32 S YlzJ-like protein
ACFBBGHA_01306 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
ACFBBGHA_01307 1.4e-133 ymfC K Transcriptional regulator
ACFBBGHA_01308 1.5e-206 ymfD EGP Major facilitator Superfamily
ACFBBGHA_01309 2.4e-234 ymfF S Peptidase M16
ACFBBGHA_01310 9.2e-242 ymfH S zinc protease
ACFBBGHA_01311 2.7e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
ACFBBGHA_01312 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
ACFBBGHA_01313 3.5e-143 ymfK S Protein of unknown function (DUF3388)
ACFBBGHA_01314 1.9e-124 ymfM S protein conserved in bacteria
ACFBBGHA_01315 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACFBBGHA_01316 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
ACFBBGHA_01317 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACFBBGHA_01318 1e-215 pbpX V Beta-lactamase
ACFBBGHA_01319 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
ACFBBGHA_01320 1.9e-152 ymdB S protein conserved in bacteria
ACFBBGHA_01321 1.2e-36 spoVS S Stage V sporulation protein S
ACFBBGHA_01322 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
ACFBBGHA_01323 4.2e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
ACFBBGHA_01324 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACFBBGHA_01325 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
ACFBBGHA_01326 2.2e-88 cotE S Spore coat protein
ACFBBGHA_01327 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACFBBGHA_01328 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACFBBGHA_01329 8.9e-70 S Regulatory protein YrvL
ACFBBGHA_01330 1.2e-97 ymcC S Membrane
ACFBBGHA_01331 4.4e-109 pksA K Transcriptional regulator
ACFBBGHA_01332 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
ACFBBGHA_01333 1.1e-161 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ACFBBGHA_01335 2.3e-184 pksD Q Acyl transferase domain
ACFBBGHA_01336 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
ACFBBGHA_01337 1.4e-37 acpK IQ Phosphopantetheine attachment site
ACFBBGHA_01338 1.3e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
ACFBBGHA_01339 3.9e-245 pksG 2.3.3.10 I synthase
ACFBBGHA_01340 1e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
ACFBBGHA_01341 1.7e-134 pksI I Belongs to the enoyl-CoA hydratase isomerase family
ACFBBGHA_01342 0.0 rhiB IQ polyketide synthase
ACFBBGHA_01343 0.0 pfaA Q Polyketide synthase of type I
ACFBBGHA_01344 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
ACFBBGHA_01345 0.0 dhbF IQ polyketide synthase
ACFBBGHA_01346 0.0 pks13 HQ Beta-ketoacyl synthase
ACFBBGHA_01347 4.1e-231 cypA C Cytochrome P450
ACFBBGHA_01348 4.4e-61 ymzB
ACFBBGHA_01349 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
ACFBBGHA_01350 1.1e-250 aprX O Belongs to the peptidase S8 family
ACFBBGHA_01351 1.9e-07 K Transcriptional regulator
ACFBBGHA_01352 2.1e-126 ymaC S Replication protein
ACFBBGHA_01353 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
ACFBBGHA_01354 8.1e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
ACFBBGHA_01355 4.9e-51 ebrA P Small Multidrug Resistance protein
ACFBBGHA_01357 2.1e-46 ymaF S YmaF family
ACFBBGHA_01358 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACFBBGHA_01359 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
ACFBBGHA_01360 8.2e-23
ACFBBGHA_01361 4.5e-22 ymzA
ACFBBGHA_01362 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
ACFBBGHA_01363 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACFBBGHA_01364 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACFBBGHA_01365 2e-109 ymaB
ACFBBGHA_01366 8.8e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ACFBBGHA_01367 8.6e-176 spoVK O stage V sporulation protein K
ACFBBGHA_01368 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACFBBGHA_01369 7.4e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
ACFBBGHA_01370 1.1e-68 glnR K transcriptional
ACFBBGHA_01371 7e-261 glnA 6.3.1.2 E glutamine synthetase
ACFBBGHA_01372 1.5e-60 L Belongs to the 'phage' integrase family
ACFBBGHA_01373 1.1e-94 3.1.4.46, 5.4.2.11 C glycerophosphoryl diester phosphodiesterase
ACFBBGHA_01374 6e-57 S Bacteriophage holin family
ACFBBGHA_01375 4.4e-37 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
ACFBBGHA_01376 4.6e-161 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ACFBBGHA_01377 6.4e-217 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
ACFBBGHA_01379 2.9e-96 ynaD J Acetyltransferase (GNAT) domain
ACFBBGHA_01381 2.6e-73 S CAAX protease self-immunity
ACFBBGHA_01382 1e-07 ywlA S Uncharacterised protein family (UPF0715)
ACFBBGHA_01383 1.5e-22 K Cro/C1-type HTH DNA-binding domain
ACFBBGHA_01384 5.4e-110 ynaE S Domain of unknown function (DUF3885)
ACFBBGHA_01387 3.2e-80 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
ACFBBGHA_01388 7.4e-253 xynT G MFS/sugar transport protein
ACFBBGHA_01389 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
ACFBBGHA_01390 7.3e-214 xylR GK ROK family
ACFBBGHA_01391 2.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
ACFBBGHA_01392 1.4e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
ACFBBGHA_01393 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
ACFBBGHA_01394 1e-254 iolT EGP Major facilitator Superfamily
ACFBBGHA_01395 6.5e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACFBBGHA_01396 2e-82 yncE S Protein of unknown function (DUF2691)
ACFBBGHA_01397 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
ACFBBGHA_01398 5.2e-15
ACFBBGHA_01401 8.6e-164 S Thymidylate synthase
ACFBBGHA_01403 3.2e-133 S Domain of unknown function, YrpD
ACFBBGHA_01406 7.9e-25 tatA U protein secretion
ACFBBGHA_01407 1.8e-71
ACFBBGHA_01408 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
ACFBBGHA_01411 1.4e-284 gerAA EG Spore germination protein
ACFBBGHA_01412 5e-196 gerAB U Spore germination
ACFBBGHA_01413 4.2e-220 gerLC S Spore germination protein
ACFBBGHA_01414 5.5e-152 yndG S DoxX-like family
ACFBBGHA_01415 1.9e-115 yndH S Domain of unknown function (DUF4166)
ACFBBGHA_01416 6.1e-307 yndJ S YndJ-like protein
ACFBBGHA_01418 4.7e-137 yndL S Replication protein
ACFBBGHA_01419 9.8e-74 yndM S Protein of unknown function (DUF2512)
ACFBBGHA_01420 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
ACFBBGHA_01421 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACFBBGHA_01422 9.9e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
ACFBBGHA_01423 4.5e-112 yneB L resolvase
ACFBBGHA_01424 1.3e-32 ynzC S UPF0291 protein
ACFBBGHA_01425 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACFBBGHA_01426 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
ACFBBGHA_01427 1.8e-28 yneF S UPF0154 protein
ACFBBGHA_01428 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
ACFBBGHA_01429 2.1e-126 ccdA O cytochrome c biogenesis protein
ACFBBGHA_01430 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
ACFBBGHA_01431 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
ACFBBGHA_01432 7.2e-74 yneK S Protein of unknown function (DUF2621)
ACFBBGHA_01433 5.9e-64 hspX O Spore coat protein
ACFBBGHA_01434 3.9e-19 sspP S Belongs to the SspP family
ACFBBGHA_01435 2.2e-14 sspO S Belongs to the SspO family
ACFBBGHA_01436 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACFBBGHA_01437 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACFBBGHA_01439 3.1e-08 sspN S Small acid-soluble spore protein N family
ACFBBGHA_01440 1.1e-34 tlp S Belongs to the Tlp family
ACFBBGHA_01441 1.2e-73 yneP S Thioesterase-like superfamily
ACFBBGHA_01442 1.3e-53 yneQ
ACFBBGHA_01443 4.1e-49 yneR S Belongs to the HesB IscA family
ACFBBGHA_01444 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
ACFBBGHA_01445 2.5e-68 yccU S CoA-binding protein
ACFBBGHA_01446 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ACFBBGHA_01447 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
ACFBBGHA_01448 2.3e-12
ACFBBGHA_01449 1.3e-57 ynfC
ACFBBGHA_01450 5.3e-251 agcS E Sodium alanine symporter
ACFBBGHA_01451 5.8e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
ACFBBGHA_01453 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
ACFBBGHA_01454 6.6e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
ACFBBGHA_01455 1.6e-79 yngA S membrane
ACFBBGHA_01456 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ACFBBGHA_01457 5.5e-104 yngC S membrane-associated protein
ACFBBGHA_01458 2.5e-233 nrnB S phosphohydrolase (DHH superfamily)
ACFBBGHA_01459 9.1e-289 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
ACFBBGHA_01460 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
ACFBBGHA_01461 1.5e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
ACFBBGHA_01462 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
ACFBBGHA_01463 5.6e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
ACFBBGHA_01464 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ACFBBGHA_01465 1.8e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
ACFBBGHA_01467 5.9e-304 yngK T Glycosyl hydrolase-like 10
ACFBBGHA_01468 1.1e-63 yngL S Protein of unknown function (DUF1360)
ACFBBGHA_01469 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
ACFBBGHA_01470 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_01471 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_01472 2.7e-94 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_01473 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
ACFBBGHA_01474 2.8e-190 yoxA 5.1.3.3 G Aldose 1-epimerase
ACFBBGHA_01475 1.9e-245 yoeA V MATE efflux family protein
ACFBBGHA_01476 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
ACFBBGHA_01478 2.2e-96 L Integrase
ACFBBGHA_01479 3e-34 yoeD G Helix-turn-helix domain
ACFBBGHA_01480 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
ACFBBGHA_01481 2e-155 gltR1 K Transcriptional regulator
ACFBBGHA_01482 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
ACFBBGHA_01483 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
ACFBBGHA_01484 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
ACFBBGHA_01485 7.8e-155 gltC K Transcriptional regulator
ACFBBGHA_01486 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACFBBGHA_01487 1.3e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACFBBGHA_01488 2e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
ACFBBGHA_01489 2e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_01490 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
ACFBBGHA_01491 1.1e-130 yoxB
ACFBBGHA_01492 1.1e-87 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
ACFBBGHA_01493 1.7e-241 S Arylsulfotransferase (ASST)
ACFBBGHA_01494 1.9e-126 3.1.1.3 I Lipase (class 3)
ACFBBGHA_01495 2.2e-232 yoaB EGP Major facilitator Superfamily
ACFBBGHA_01496 6.7e-281 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
ACFBBGHA_01497 4.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACFBBGHA_01498 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ACFBBGHA_01499 1.1e-33 yoaF
ACFBBGHA_01500 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
ACFBBGHA_01501 7.7e-13
ACFBBGHA_01502 7.7e-35 S Protein of unknown function (DUF4025)
ACFBBGHA_01503 6.3e-182 mcpU NT methyl-accepting chemotaxis protein
ACFBBGHA_01504 2.1e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
ACFBBGHA_01505 1.2e-131 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
ACFBBGHA_01506 2.3e-111 yoaK S Membrane
ACFBBGHA_01507 3.6e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
ACFBBGHA_01508 3.2e-132 yoqW S Belongs to the SOS response-associated peptidase family
ACFBBGHA_01511 1.3e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
ACFBBGHA_01513 1.6e-76 yoaP 3.1.3.18 K YoaP-like
ACFBBGHA_01514 5.3e-57 yoaP 3.1.3.18 K YoaP-like
ACFBBGHA_01515 2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
ACFBBGHA_01517 6.8e-84
ACFBBGHA_01518 7.1e-172 yoaR V vancomycin resistance protein
ACFBBGHA_01519 7.3e-75 yoaS S Protein of unknown function (DUF2975)
ACFBBGHA_01520 4.2e-37 yozG K Transcriptional regulator
ACFBBGHA_01521 1.8e-147 yoaT S Protein of unknown function (DUF817)
ACFBBGHA_01522 7.3e-158 yoaU K LysR substrate binding domain
ACFBBGHA_01523 1.6e-157 yijE EG EamA-like transporter family
ACFBBGHA_01524 6.3e-78 yoaW
ACFBBGHA_01525 5e-116 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
ACFBBGHA_01526 7e-167 bla 3.5.2.6 V beta-lactamase
ACFBBGHA_01529 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
ACFBBGHA_01530 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
ACFBBGHA_01532 1.4e-37 S TM2 domain
ACFBBGHA_01533 4.1e-56 K Helix-turn-helix
ACFBBGHA_01534 8e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
ACFBBGHA_01535 3.1e-23 yoqW S Belongs to the SOS response-associated peptidase family
ACFBBGHA_01536 1.9e-23 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACFBBGHA_01537 2.7e-179 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
ACFBBGHA_01538 5.2e-131 purR15 K Bacterial regulatory proteins, lacI family
ACFBBGHA_01539 2.4e-216 3.2.1.86 GT1 G Glycosyl hydrolase family 1
ACFBBGHA_01541 7.5e-95 G Bacterial extracellular solute-binding protein
ACFBBGHA_01542 4.4e-102 P COG0395 ABC-type sugar transport system, permease component
ACFBBGHA_01543 6.8e-103 G Binding-protein-dependent transport system inner membrane component
ACFBBGHA_01544 0.0 rafA 3.2.1.22 G Alpha-galactosidase
ACFBBGHA_01545 6.5e-107 ypbG 2.7.1.2 GK ROK family
ACFBBGHA_01546 3.3e-85 S SMI1-KNR4 cell-wall
ACFBBGHA_01547 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
ACFBBGHA_01548 1.1e-101 yokH G SMI1 / KNR4 family
ACFBBGHA_01549 7.5e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
ACFBBGHA_01550 6.4e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
ACFBBGHA_01551 1.4e-133 yobQ K helix_turn_helix, arabinose operon control protein
ACFBBGHA_01552 3.1e-141 yobR 2.3.1.1 J FR47-like protein
ACFBBGHA_01553 1.1e-98 yobS K Transcriptional regulator
ACFBBGHA_01554 9.5e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
ACFBBGHA_01555 3.4e-88 yobU K Bacterial transcription activator, effector binding domain
ACFBBGHA_01556 7.1e-175 yobV K WYL domain
ACFBBGHA_01557 3e-93 yobW
ACFBBGHA_01558 1e-51 czrA K transcriptional
ACFBBGHA_01559 1.1e-116 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
ACFBBGHA_01560 1.5e-92 yozB S membrane
ACFBBGHA_01561 2.1e-143
ACFBBGHA_01562 1.6e-93 yocC
ACFBBGHA_01563 2.4e-186 yocD 3.4.17.13 V peptidase S66
ACFBBGHA_01564 3.4e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
ACFBBGHA_01565 7.1e-198 desK 2.7.13.3 T Histidine kinase
ACFBBGHA_01566 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ACFBBGHA_01567 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
ACFBBGHA_01568 0.0 recQ 3.6.4.12 L DNA helicase
ACFBBGHA_01569 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACFBBGHA_01570 3.3e-83 dksA T general stress protein
ACFBBGHA_01571 8.4e-54 yocL
ACFBBGHA_01572 6.2e-32
ACFBBGHA_01573 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
ACFBBGHA_01574 1.1e-40 yozN
ACFBBGHA_01575 1.9e-36 yocN
ACFBBGHA_01576 4.2e-56 yozO S Bacterial PH domain
ACFBBGHA_01577 3.2e-31 yozC
ACFBBGHA_01578 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
ACFBBGHA_01579 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
ACFBBGHA_01580 6e-165 sodA 1.15.1.1 P Superoxide dismutase
ACFBBGHA_01581 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
ACFBBGHA_01582 8.6e-168 yocS S -transporter
ACFBBGHA_01583 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
ACFBBGHA_01584 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
ACFBBGHA_01585 0.0 yojO P Von Willebrand factor
ACFBBGHA_01586 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
ACFBBGHA_01587 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACFBBGHA_01588 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
ACFBBGHA_01589 9e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
ACFBBGHA_01590 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ACFBBGHA_01592 6.1e-244 norM V Multidrug efflux pump
ACFBBGHA_01593 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ACFBBGHA_01594 2.1e-125 yojG S deacetylase
ACFBBGHA_01595 2.2e-60 yojF S Protein of unknown function (DUF1806)
ACFBBGHA_01596 1.5e-43
ACFBBGHA_01597 5.6e-161 rarD S -transporter
ACFBBGHA_01598 1.9e-64 yozR S COG0071 Molecular chaperone (small heat shock protein)
ACFBBGHA_01599 3.4e-09
ACFBBGHA_01600 3.8e-206 gntP EG COG2610 H gluconate symporter and related permeases
ACFBBGHA_01601 8e-64 yodA S tautomerase
ACFBBGHA_01602 4.4e-55 yodB K transcriptional
ACFBBGHA_01603 4.1e-107 yodC C nitroreductase
ACFBBGHA_01604 3.8e-113 mhqD S Carboxylesterase
ACFBBGHA_01605 2.1e-171 yodE E COG0346 Lactoylglutathione lyase and related lyases
ACFBBGHA_01606 6.2e-28 S Protein of unknown function (DUF3311)
ACFBBGHA_01607 5.1e-268 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACFBBGHA_01608 3.1e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
ACFBBGHA_01609 3.2e-127 yodH Q Methyltransferase
ACFBBGHA_01610 5.2e-24 yodI
ACFBBGHA_01611 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
ACFBBGHA_01612 1.2e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
ACFBBGHA_01613 5.3e-09
ACFBBGHA_01614 3.6e-54 yodL S YodL-like
ACFBBGHA_01615 1.3e-105 yodM 3.6.1.27 I Acid phosphatase homologues
ACFBBGHA_01616 2.8e-24 yozD S YozD-like protein
ACFBBGHA_01618 1.6e-123 yodN
ACFBBGHA_01619 1.4e-36 yozE S Belongs to the UPF0346 family
ACFBBGHA_01620 2.9e-47 yokU S YokU-like protein, putative antitoxin
ACFBBGHA_01621 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
ACFBBGHA_01622 5.7e-152 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
ACFBBGHA_01623 1.3e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
ACFBBGHA_01624 8e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
ACFBBGHA_01625 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACFBBGHA_01626 2.3e-248 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACFBBGHA_01628 1.2e-143 yiiD K acetyltransferase
ACFBBGHA_01629 8.5e-256 cgeD M maturation of the outermost layer of the spore
ACFBBGHA_01630 3.5e-38 cgeC
ACFBBGHA_01631 1.5e-65 cgeA
ACFBBGHA_01632 3.1e-186 cgeB S Spore maturation protein
ACFBBGHA_01633 3.7e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
ACFBBGHA_01634 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
ACFBBGHA_01635 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
ACFBBGHA_01636 2.9e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACFBBGHA_01637 1.6e-70 ypoP K transcriptional
ACFBBGHA_01638 1.1e-221 mepA V MATE efflux family protein
ACFBBGHA_01639 2.1e-28 ypmT S Uncharacterized ympT
ACFBBGHA_01640 1.1e-98 ypmS S protein conserved in bacteria
ACFBBGHA_01641 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
ACFBBGHA_01642 1.3e-107 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
ACFBBGHA_01643 3.4e-39 ypmP S Protein of unknown function (DUF2535)
ACFBBGHA_01644 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACFBBGHA_01645 5.2e-184 pspF K Transcriptional regulator
ACFBBGHA_01646 4.2e-110 hlyIII S protein, Hemolysin III
ACFBBGHA_01647 3.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
ACFBBGHA_01648 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACFBBGHA_01649 1.1e-155 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ACFBBGHA_01650 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
ACFBBGHA_01651 7.8e-114 ypjP S YpjP-like protein
ACFBBGHA_01652 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
ACFBBGHA_01653 1.7e-75 yphP S Belongs to the UPF0403 family
ACFBBGHA_01654 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
ACFBBGHA_01655 5.2e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
ACFBBGHA_01656 2.1e-106 ypgQ S phosphohydrolase
ACFBBGHA_01657 1.5e-88 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
ACFBBGHA_01658 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACFBBGHA_01660 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
ACFBBGHA_01661 7.9e-31 cspD K Cold-shock protein
ACFBBGHA_01662 3.8e-16 degR
ACFBBGHA_01663 5.2e-30 S Protein of unknown function (DUF2564)
ACFBBGHA_01664 2.6e-27 ypeQ S Zinc-finger
ACFBBGHA_01665 1e-134 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
ACFBBGHA_01666 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACFBBGHA_01667 4.2e-68 rnhA 3.1.26.4 L Ribonuclease
ACFBBGHA_01669 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
ACFBBGHA_01670 2e-07
ACFBBGHA_01671 1e-38 ypbS S Protein of unknown function (DUF2533)
ACFBBGHA_01672 0.0 ypbR S Dynamin family
ACFBBGHA_01673 5.1e-87 ypbQ S protein conserved in bacteria
ACFBBGHA_01674 4.4e-208 bcsA Q Naringenin-chalcone synthase
ACFBBGHA_01675 1.6e-228 pbuX F xanthine
ACFBBGHA_01676 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
ACFBBGHA_01677 9.6e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ACFBBGHA_01678 2.1e-169 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
ACFBBGHA_01679 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
ACFBBGHA_01680 2.4e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
ACFBBGHA_01681 8.2e-185 ptxS K transcriptional
ACFBBGHA_01682 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
ACFBBGHA_01683 2e-121 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_01684 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
ACFBBGHA_01686 3.9e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
ACFBBGHA_01687 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
ACFBBGHA_01688 8.2e-91 ypsA S Belongs to the UPF0398 family
ACFBBGHA_01689 5.1e-237 yprB L RNase_H superfamily
ACFBBGHA_01690 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
ACFBBGHA_01691 1.1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
ACFBBGHA_01692 3.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
ACFBBGHA_01693 1.2e-48 yppG S YppG-like protein
ACFBBGHA_01695 2.6e-11 yppE S Bacterial domain of unknown function (DUF1798)
ACFBBGHA_01698 8.3e-187 yppC S Protein of unknown function (DUF2515)
ACFBBGHA_01699 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
ACFBBGHA_01700 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
ACFBBGHA_01701 4.7e-93 ypoC
ACFBBGHA_01702 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACFBBGHA_01703 5.7e-129 dnaD L DNA replication protein DnaD
ACFBBGHA_01704 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
ACFBBGHA_01705 7.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
ACFBBGHA_01706 2.2e-79 ypmB S protein conserved in bacteria
ACFBBGHA_01707 1.9e-22 ypmA S Protein of unknown function (DUF4264)
ACFBBGHA_01708 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
ACFBBGHA_01709 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACFBBGHA_01710 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACFBBGHA_01711 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
ACFBBGHA_01712 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
ACFBBGHA_01713 3.9e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ACFBBGHA_01714 5.3e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
ACFBBGHA_01715 1.3e-128 bshB1 S proteins, LmbE homologs
ACFBBGHA_01716 7.9e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
ACFBBGHA_01717 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
ACFBBGHA_01718 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
ACFBBGHA_01719 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
ACFBBGHA_01720 1e-142 ypjB S sporulation protein
ACFBBGHA_01721 3.4e-98 ypjA S membrane
ACFBBGHA_01722 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
ACFBBGHA_01723 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
ACFBBGHA_01724 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
ACFBBGHA_01725 1.4e-75 ypiF S Protein of unknown function (DUF2487)
ACFBBGHA_01726 2.8e-99 ypiB S Belongs to the UPF0302 family
ACFBBGHA_01727 2.7e-233 S COG0457 FOG TPR repeat
ACFBBGHA_01728 2.2e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
ACFBBGHA_01729 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
ACFBBGHA_01730 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACFBBGHA_01731 3.6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
ACFBBGHA_01732 5.2e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ACFBBGHA_01733 1.2e-117 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
ACFBBGHA_01734 1.4e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
ACFBBGHA_01735 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACFBBGHA_01736 6.8e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACFBBGHA_01737 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
ACFBBGHA_01738 1.1e-203 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACFBBGHA_01739 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACFBBGHA_01740 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
ACFBBGHA_01741 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
ACFBBGHA_01742 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ACFBBGHA_01743 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
ACFBBGHA_01744 1.6e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
ACFBBGHA_01745 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
ACFBBGHA_01746 2.7e-100 folE 3.5.4.16 H GTP cyclohydrolase
ACFBBGHA_01747 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
ACFBBGHA_01748 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ACFBBGHA_01749 6e-137 yphF
ACFBBGHA_01750 1.6e-18 yphE S Protein of unknown function (DUF2768)
ACFBBGHA_01751 1.9e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
ACFBBGHA_01752 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
ACFBBGHA_01753 7.9e-28 ypzH
ACFBBGHA_01754 7.2e-161 seaA S YIEGIA protein
ACFBBGHA_01755 6.7e-102 yphA
ACFBBGHA_01756 1.4e-07 S YpzI-like protein
ACFBBGHA_01757 2.5e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
ACFBBGHA_01758 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
ACFBBGHA_01759 3.6e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
ACFBBGHA_01760 1.8e-23 S Family of unknown function (DUF5359)
ACFBBGHA_01761 1e-111 ypfA M Flagellar protein YcgR
ACFBBGHA_01762 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
ACFBBGHA_01763 2.8e-152 sleB 3.5.1.28 M Spore cortex-lytic enzyme
ACFBBGHA_01764 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
ACFBBGHA_01765 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
ACFBBGHA_01766 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
ACFBBGHA_01767 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
ACFBBGHA_01768 2.6e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
ACFBBGHA_01769 2.8e-81 ypbF S Protein of unknown function (DUF2663)
ACFBBGHA_01770 1.3e-75 ypbE M Lysin motif
ACFBBGHA_01771 1.1e-99 ypbD S metal-dependent membrane protease
ACFBBGHA_01772 9.2e-286 recQ 3.6.4.12 L DNA helicase
ACFBBGHA_01773 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
ACFBBGHA_01774 4.7e-41 fer C Ferredoxin
ACFBBGHA_01775 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ACFBBGHA_01776 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACFBBGHA_01777 3.4e-135 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
ACFBBGHA_01778 8.3e-199 rsiX
ACFBBGHA_01779 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_01780 0.0 resE 2.7.13.3 T Histidine kinase
ACFBBGHA_01781 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_01782 8.8e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
ACFBBGHA_01783 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
ACFBBGHA_01784 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
ACFBBGHA_01785 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ACFBBGHA_01786 5.4e-87 spmB S Spore maturation protein
ACFBBGHA_01787 3.5e-103 spmA S Spore maturation protein
ACFBBGHA_01788 2e-211 dacB 3.4.16.4 M Belongs to the peptidase S11 family
ACFBBGHA_01789 7.6e-97 ypuI S Protein of unknown function (DUF3907)
ACFBBGHA_01790 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACFBBGHA_01791 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACFBBGHA_01792 3.6e-91 ypuF S Domain of unknown function (DUF309)
ACFBBGHA_01793 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ACFBBGHA_01794 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
ACFBBGHA_01795 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACFBBGHA_01796 7.4e-115 ribE 2.5.1.9 H Riboflavin synthase
ACFBBGHA_01797 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACFBBGHA_01798 7.8e-55 ypuD
ACFBBGHA_01799 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
ACFBBGHA_01800 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
ACFBBGHA_01801 4.7e-13 S PAP2 superfamily
ACFBBGHA_01804 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACFBBGHA_01805 8.1e-149 ypuA S Secreted protein
ACFBBGHA_01806 6.8e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
ACFBBGHA_01807 1.4e-273 spoVAF EG Stage V sporulation protein AF
ACFBBGHA_01808 1.4e-110 spoVAEA S stage V sporulation protein
ACFBBGHA_01809 2.2e-57 spoVAEB S stage V sporulation protein
ACFBBGHA_01810 9e-192 spoVAD I Stage V sporulation protein AD
ACFBBGHA_01811 1.5e-77 spoVAC S stage V sporulation protein AC
ACFBBGHA_01812 1e-67 spoVAB S Stage V sporulation protein AB
ACFBBGHA_01813 9.6e-112 spoVAA S Stage V sporulation protein AA
ACFBBGHA_01814 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACFBBGHA_01815 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
ACFBBGHA_01816 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
ACFBBGHA_01817 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
ACFBBGHA_01818 1.9e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACFBBGHA_01819 1.1e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
ACFBBGHA_01820 5.7e-166 xerD L recombinase XerD
ACFBBGHA_01821 1.4e-36 S Protein of unknown function (DUF4227)
ACFBBGHA_01822 2.4e-80 fur P Belongs to the Fur family
ACFBBGHA_01823 8.2e-106 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
ACFBBGHA_01824 1.2e-29 yqkK
ACFBBGHA_01825 1.2e-241 mleA 1.1.1.38 C malic enzyme
ACFBBGHA_01826 9.1e-235 mleN C Na H antiporter
ACFBBGHA_01827 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
ACFBBGHA_01828 4.7e-185 ansA 3.5.1.1 EJ L-asparaginase
ACFBBGHA_01829 1.3e-57 ansR K Transcriptional regulator
ACFBBGHA_01830 2.6e-219 yqxK 3.6.4.12 L DNA helicase
ACFBBGHA_01831 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
ACFBBGHA_01833 3.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
ACFBBGHA_01834 3.1e-12 yqkE S Protein of unknown function (DUF3886)
ACFBBGHA_01835 1.9e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
ACFBBGHA_01836 9.4e-39 yqkC S Protein of unknown function (DUF2552)
ACFBBGHA_01837 2.8e-54 yqkB S Belongs to the HesB IscA family
ACFBBGHA_01838 5.7e-194 yqkA K GrpB protein
ACFBBGHA_01839 6.8e-59 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
ACFBBGHA_01840 4e-86 yqjY K acetyltransferase
ACFBBGHA_01841 5.7e-50 S YolD-like protein
ACFBBGHA_01842 2.3e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACFBBGHA_01844 1.1e-223 yqjV G Major Facilitator Superfamily
ACFBBGHA_01846 3e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ACFBBGHA_01847 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
ACFBBGHA_01848 4.6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
ACFBBGHA_01849 6.6e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_01850 8.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
ACFBBGHA_01851 1.1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACFBBGHA_01852 0.0 rocB E arginine degradation protein
ACFBBGHA_01853 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
ACFBBGHA_01854 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
ACFBBGHA_01855 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ACFBBGHA_01856 8.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
ACFBBGHA_01857 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACFBBGHA_01858 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACFBBGHA_01859 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACFBBGHA_01860 4.5e-24 yqzJ
ACFBBGHA_01861 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACFBBGHA_01862 9.8e-140 yqjF S Uncharacterized conserved protein (COG2071)
ACFBBGHA_01863 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
ACFBBGHA_01864 1.8e-289 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
ACFBBGHA_01865 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
ACFBBGHA_01867 3e-98 yqjB S protein conserved in bacteria
ACFBBGHA_01868 9.6e-175 yqjA S Putative aromatic acid exporter C-terminal domain
ACFBBGHA_01869 7.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ACFBBGHA_01870 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
ACFBBGHA_01871 1.8e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
ACFBBGHA_01872 9.3e-77 yqiW S Belongs to the UPF0403 family
ACFBBGHA_01873 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ACFBBGHA_01874 7.9e-208 norA EGP Major facilitator Superfamily
ACFBBGHA_01875 1.4e-150 bmrR K helix_turn_helix, mercury resistance
ACFBBGHA_01876 9.2e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ACFBBGHA_01877 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ACFBBGHA_01878 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ACFBBGHA_01879 9.8e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ACFBBGHA_01880 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
ACFBBGHA_01881 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
ACFBBGHA_01882 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
ACFBBGHA_01883 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
ACFBBGHA_01884 4e-34 yqzF S Protein of unknown function (DUF2627)
ACFBBGHA_01885 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ACFBBGHA_01886 5.3e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
ACFBBGHA_01887 1.7e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
ACFBBGHA_01888 2e-211 mmgC I acyl-CoA dehydrogenase
ACFBBGHA_01889 1e-156 hbdA 1.1.1.157 I Dehydrogenase
ACFBBGHA_01890 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
ACFBBGHA_01891 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
ACFBBGHA_01892 8.6e-105 amiC 3.5.1.28 M Cell wall hydrolase autolysin
ACFBBGHA_01893 2.3e-26
ACFBBGHA_01894 2.1e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
ACFBBGHA_01896 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
ACFBBGHA_01897 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
ACFBBGHA_01898 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
ACFBBGHA_01899 1.7e-78 argR K Regulates arginine biosynthesis genes
ACFBBGHA_01900 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
ACFBBGHA_01901 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACFBBGHA_01902 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
ACFBBGHA_01903 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ACFBBGHA_01904 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
ACFBBGHA_01905 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACFBBGHA_01906 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACFBBGHA_01907 2.1e-67 yqhY S protein conserved in bacteria
ACFBBGHA_01908 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
ACFBBGHA_01909 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
ACFBBGHA_01910 9.9e-91 spoIIIAH S SpoIIIAH-like protein
ACFBBGHA_01911 6.5e-109 spoIIIAG S stage III sporulation protein AG
ACFBBGHA_01912 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
ACFBBGHA_01913 1.3e-197 spoIIIAE S stage III sporulation protein AE
ACFBBGHA_01914 2.3e-58 spoIIIAD S Stage III sporulation protein AD
ACFBBGHA_01915 7.6e-29 spoIIIAC S stage III sporulation protein AC
ACFBBGHA_01916 1.1e-84 spoIIIAB S Stage III sporulation protein
ACFBBGHA_01917 4e-170 spoIIIAA S stage III sporulation protein AA
ACFBBGHA_01918 7.9e-37 yqhV S Protein of unknown function (DUF2619)
ACFBBGHA_01919 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACFBBGHA_01920 1.7e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
ACFBBGHA_01921 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
ACFBBGHA_01922 2.3e-93 yqhR S Conserved membrane protein YqhR
ACFBBGHA_01923 8e-174 yqhQ S Protein of unknown function (DUF1385)
ACFBBGHA_01924 2.2e-61 yqhP
ACFBBGHA_01925 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
ACFBBGHA_01926 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
ACFBBGHA_01927 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
ACFBBGHA_01928 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
ACFBBGHA_01929 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACFBBGHA_01930 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACFBBGHA_01931 2.1e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
ACFBBGHA_01932 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
ACFBBGHA_01933 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
ACFBBGHA_01934 1.2e-24 sinI S Anti-repressor SinI
ACFBBGHA_01935 1e-54 sinR K transcriptional
ACFBBGHA_01936 1.2e-140 tasA S Cell division protein FtsN
ACFBBGHA_01937 6.7e-59 sipW 3.4.21.89 U Signal peptidase
ACFBBGHA_01938 2.7e-116 yqxM
ACFBBGHA_01939 7.3e-54 yqzG S Protein of unknown function (DUF3889)
ACFBBGHA_01940 1.4e-26 yqzE S YqzE-like protein
ACFBBGHA_01941 4e-44 S ComG operon protein 7
ACFBBGHA_01942 1.2e-45 comGF U Putative Competence protein ComGF
ACFBBGHA_01943 1.1e-59 comGE
ACFBBGHA_01944 4.4e-71 gspH NU protein transport across the cell outer membrane
ACFBBGHA_01945 1.4e-47 comGC U Required for transformation and DNA binding
ACFBBGHA_01946 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
ACFBBGHA_01947 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACFBBGHA_01949 4e-173 corA P Mg2 transporter protein
ACFBBGHA_01950 3.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
ACFBBGHA_01951 2.7e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ACFBBGHA_01953 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
ACFBBGHA_01954 1.8e-37 yqgY S Protein of unknown function (DUF2626)
ACFBBGHA_01955 1.8e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
ACFBBGHA_01956 8.9e-23 yqgW S Protein of unknown function (DUF2759)
ACFBBGHA_01957 6.9e-50 yqgV S Thiamine-binding protein
ACFBBGHA_01958 8.8e-198 yqgU
ACFBBGHA_01959 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
ACFBBGHA_01960 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ACFBBGHA_01961 5.2e-181 glcK 2.7.1.2 G Glucokinase
ACFBBGHA_01962 3.1e-33 yqgQ S Protein conserved in bacteria
ACFBBGHA_01963 8.9e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
ACFBBGHA_01964 2.5e-09 yqgO
ACFBBGHA_01965 2.5e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACFBBGHA_01966 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
ACFBBGHA_01967 2e-197 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
ACFBBGHA_01969 9.2e-51 yqzD
ACFBBGHA_01970 7.3e-72 yqzC S YceG-like family
ACFBBGHA_01971 4.9e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ACFBBGHA_01972 3.2e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
ACFBBGHA_01973 4.4e-158 pstA P Phosphate transport system permease
ACFBBGHA_01974 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
ACFBBGHA_01975 3.1e-143 pstS P Phosphate
ACFBBGHA_01976 0.0 pbpA 3.4.16.4 M penicillin-binding protein
ACFBBGHA_01977 2.5e-231 yqgE EGP Major facilitator superfamily
ACFBBGHA_01978 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
ACFBBGHA_01979 4e-73 yqgC S protein conserved in bacteria
ACFBBGHA_01980 3.9e-131 yqgB S Protein of unknown function (DUF1189)
ACFBBGHA_01981 1.5e-46 yqfZ M LysM domain
ACFBBGHA_01982 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACFBBGHA_01983 4.3e-62 yqfX S membrane
ACFBBGHA_01984 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
ACFBBGHA_01985 1.9e-77 zur P Belongs to the Fur family
ACFBBGHA_01986 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
ACFBBGHA_01987 2.1e-36 yqfT S Protein of unknown function (DUF2624)
ACFBBGHA_01988 3.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACFBBGHA_01989 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
ACFBBGHA_01990 2.9e-14 yqfQ S YqfQ-like protein
ACFBBGHA_01991 4.9e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACFBBGHA_01992 5.6e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACFBBGHA_01993 2.6e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
ACFBBGHA_01994 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
ACFBBGHA_01995 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
ACFBBGHA_01996 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
ACFBBGHA_01997 4.5e-88 yaiI S Belongs to the UPF0178 family
ACFBBGHA_01998 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
ACFBBGHA_01999 4.5e-112 ccpN K CBS domain
ACFBBGHA_02000 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
ACFBBGHA_02001 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
ACFBBGHA_02002 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
ACFBBGHA_02003 8.4e-19 S YqzL-like protein
ACFBBGHA_02004 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACFBBGHA_02005 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
ACFBBGHA_02006 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
ACFBBGHA_02007 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACFBBGHA_02008 0.0 yqfF S membrane-associated HD superfamily hydrolase
ACFBBGHA_02010 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
ACFBBGHA_02011 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
ACFBBGHA_02012 2.7e-45 yqfC S sporulation protein YqfC
ACFBBGHA_02013 3.7e-22 yqfB
ACFBBGHA_02014 4.3e-122 yqfA S UPF0365 protein
ACFBBGHA_02015 4.5e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
ACFBBGHA_02016 2.5e-61 yqeY S Yqey-like protein
ACFBBGHA_02017 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
ACFBBGHA_02018 3.9e-157 yqeW P COG1283 Na phosphate symporter
ACFBBGHA_02019 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
ACFBBGHA_02020 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
ACFBBGHA_02021 4.6e-174 prmA J Methylates ribosomal protein L11
ACFBBGHA_02022 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
ACFBBGHA_02023 0.0 dnaK O Heat shock 70 kDa protein
ACFBBGHA_02024 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACFBBGHA_02025 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
ACFBBGHA_02026 2.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
ACFBBGHA_02027 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
ACFBBGHA_02028 3.6e-52 yqxA S Protein of unknown function (DUF3679)
ACFBBGHA_02029 1.5e-222 spoIIP M stage II sporulation protein P
ACFBBGHA_02030 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ACFBBGHA_02031 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
ACFBBGHA_02032 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
ACFBBGHA_02033 4.1e-15 S YqzM-like protein
ACFBBGHA_02034 0.0 comEC S Competence protein ComEC
ACFBBGHA_02035 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
ACFBBGHA_02036 2.5e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
ACFBBGHA_02037 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACFBBGHA_02038 3.2e-138 yqeM Q Methyltransferase
ACFBBGHA_02039 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
ACFBBGHA_02040 6.2e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
ACFBBGHA_02041 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACFBBGHA_02042 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
ACFBBGHA_02043 2.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACFBBGHA_02044 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
ACFBBGHA_02045 5.3e-95 yqeG S hydrolase of the HAD superfamily
ACFBBGHA_02047 4e-141 yqeF E GDSL-like Lipase/Acylhydrolase
ACFBBGHA_02048 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ACFBBGHA_02049 1.5e-104 yqeD S SNARE associated Golgi protein
ACFBBGHA_02050 1e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
ACFBBGHA_02051 2.3e-133 yqeB
ACFBBGHA_02052 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
ACFBBGHA_02053 2.8e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACFBBGHA_02054 5.3e-62 napB K helix_turn_helix multiple antibiotic resistance protein
ACFBBGHA_02055 4.9e-220 yfjF U Belongs to the major facilitator superfamily
ACFBBGHA_02056 3.5e-277 cisA2 L Recombinase
ACFBBGHA_02057 2.8e-151 smc L AAA ATPase domain
ACFBBGHA_02058 0.0 L response to ionizing radiation
ACFBBGHA_02059 8.4e-72
ACFBBGHA_02061 1.8e-201 S Aspartate phosphatase response regulator
ACFBBGHA_02062 4e-197 A Pre-toxin TG
ACFBBGHA_02063 9.5e-42
ACFBBGHA_02064 7.9e-100 S Suppressor of fused protein (SUFU)
ACFBBGHA_02065 2.7e-51 S Immunity protein 50
ACFBBGHA_02066 2.2e-30 S SMI1 / KNR4 family
ACFBBGHA_02067 4e-22 S SMI1-KNR4 cell-wall
ACFBBGHA_02068 2.1e-70 yokH G SMI1 / KNR4 family
ACFBBGHA_02069 2.4e-56 V HNH endonuclease
ACFBBGHA_02070 9.7e-127 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
ACFBBGHA_02071 2.6e-68 S Bacteriophage holin family
ACFBBGHA_02072 1.6e-160 xepA
ACFBBGHA_02073 3.5e-21
ACFBBGHA_02074 3e-51 xkdW S XkdW protein
ACFBBGHA_02075 5e-220
ACFBBGHA_02076 2.4e-38
ACFBBGHA_02077 6.7e-99 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
ACFBBGHA_02078 2.6e-186 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
ACFBBGHA_02079 1.1e-69 xkdS S Protein of unknown function (DUF2634)
ACFBBGHA_02080 5.6e-37 xkdR S Protein of unknown function (DUF2577)
ACFBBGHA_02081 2.8e-174 yqbQ 3.2.1.96 G NLP P60 protein
ACFBBGHA_02082 3.8e-112 xkdP S Lysin motif
ACFBBGHA_02083 0.0 xkdO L Transglycosylase SLT domain
ACFBBGHA_02084 2.8e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
ACFBBGHA_02085 6.1e-76 xkdM S Phage tail tube protein
ACFBBGHA_02086 2.2e-252 xkdK S Phage tail sheath C-terminal domain
ACFBBGHA_02087 2.7e-25
ACFBBGHA_02088 1.3e-75
ACFBBGHA_02089 6.7e-87 S Bacteriophage HK97-gp10, putative tail-component
ACFBBGHA_02090 9.7e-64 yqbH S Domain of unknown function (DUF3599)
ACFBBGHA_02091 6e-67 S Protein of unknown function (DUF3199)
ACFBBGHA_02092 2.3e-45 S YqbF, hypothetical protein domain
ACFBBGHA_02093 4.6e-166 xkdG S Phage capsid family
ACFBBGHA_02094 3.8e-115 yqbD 2.1.1.72 L Putative phage serine protease XkdF
ACFBBGHA_02095 6.4e-41
ACFBBGHA_02096 7e-143 S Phage Mu protein F like protein
ACFBBGHA_02097 8.6e-287 yqbA S portal protein
ACFBBGHA_02098 1e-248 S phage terminase, large subunit
ACFBBGHA_02099 4.3e-95 yqaS L DNA packaging
ACFBBGHA_02100 4.6e-31
ACFBBGHA_02102 1.3e-76 L Transposase
ACFBBGHA_02105 4.1e-30 yqaO S Phage-like element PBSX protein XtrA
ACFBBGHA_02106 9.7e-71 rusA L Endodeoxyribonuclease RusA
ACFBBGHA_02108 2e-160 xkdC L IstB-like ATP binding protein
ACFBBGHA_02109 6e-118 3.1.3.16 L DnaD domain protein
ACFBBGHA_02110 4.2e-150 recT L RecT family
ACFBBGHA_02111 1e-173 yqaJ L YqaJ-like viral recombinase domain
ACFBBGHA_02115 4.4e-103
ACFBBGHA_02117 3.6e-18 K Helix-turn-helix XRE-family like proteins
ACFBBGHA_02118 1.1e-32 K sequence-specific DNA binding
ACFBBGHA_02120 1.9e-100 adk 2.7.4.3 F adenylate kinase activity
ACFBBGHA_02121 2.2e-93 yqaB E IrrE N-terminal-like domain
ACFBBGHA_02122 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACFBBGHA_02123 2e-68 psiE S Protein PsiE homolog
ACFBBGHA_02124 9e-237 yrkQ T Histidine kinase
ACFBBGHA_02125 1.1e-127 T Transcriptional regulator
ACFBBGHA_02126 8.2e-224 yrkO P Protein of unknown function (DUF418)
ACFBBGHA_02127 1.5e-103 yrkN K Acetyltransferase (GNAT) family
ACFBBGHA_02128 1.5e-97 ywrO S Flavodoxin-like fold
ACFBBGHA_02129 2.8e-79 S Protein of unknown function with HXXEE motif
ACFBBGHA_02130 5.4e-112 yrkJ S membrane transporter protein
ACFBBGHA_02131 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
ACFBBGHA_02132 6e-205 yrkH P Rhodanese Homology Domain
ACFBBGHA_02133 7.9e-45 perX S DsrE/DsrF-like family
ACFBBGHA_02134 7.9e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
ACFBBGHA_02135 4.3e-83 yrkE O DsrE/DsrF/DrsH-like family
ACFBBGHA_02136 7.8e-39 yrkD S protein conserved in bacteria
ACFBBGHA_02137 1.3e-107 yrkC G Cupin domain
ACFBBGHA_02138 3.4e-149 bltR K helix_turn_helix, mercury resistance
ACFBBGHA_02139 1e-210 blt EGP Major facilitator Superfamily
ACFBBGHA_02140 1.5e-82 bltD 2.3.1.57 K FR47-like protein
ACFBBGHA_02141 1.3e-235 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
ACFBBGHA_02142 3.9e-16 S YrzO-like protein
ACFBBGHA_02143 1.4e-170 yrdR EG EamA-like transporter family
ACFBBGHA_02144 5.6e-158 yrdQ K Transcriptional regulator
ACFBBGHA_02145 3.3e-197 trkA P Oxidoreductase
ACFBBGHA_02146 2.2e-147 czcD P COG1230 Co Zn Cd efflux system component
ACFBBGHA_02147 3.2e-65 yodA S tautomerase
ACFBBGHA_02148 5e-162 gltR K LysR substrate binding domain
ACFBBGHA_02149 3.3e-226 brnQ E Component of the transport system for branched-chain amino acids
ACFBBGHA_02150 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
ACFBBGHA_02151 2.8e-137 azlC E AzlC protein
ACFBBGHA_02152 1.1e-78 bkdR K helix_turn_helix ASNC type
ACFBBGHA_02153 8.3e-24 yrdF K ribonuclease inhibitor
ACFBBGHA_02154 1.2e-230 cypA C Cytochrome P450
ACFBBGHA_02155 1e-99 yrdC 3.5.1.19 Q Isochorismatase family
ACFBBGHA_02156 4.4e-54 S Protein of unknown function (DUF2568)
ACFBBGHA_02157 2.7e-88 yrdA S DinB family
ACFBBGHA_02158 1.2e-165 aadK G Streptomycin adenylyltransferase
ACFBBGHA_02159 2.4e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
ACFBBGHA_02160 2.7e-79 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ACFBBGHA_02161 1.6e-123 yrpD S Domain of unknown function, YrpD
ACFBBGHA_02163 9.6e-114 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
ACFBBGHA_02164 2.1e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_02165 4.5e-188 yrpG C Aldo/keto reductase family
ACFBBGHA_02166 1e-224 yraO C Citrate transporter
ACFBBGHA_02167 3.7e-162 yraN K Transcriptional regulator
ACFBBGHA_02168 6.5e-204 yraM S PrpF protein
ACFBBGHA_02169 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
ACFBBGHA_02170 5.1e-39 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ACFBBGHA_02171 6e-154 S Alpha beta hydrolase
ACFBBGHA_02172 1.7e-60 T sh3 domain protein
ACFBBGHA_02173 2.4e-61 T sh3 domain protein
ACFBBGHA_02175 3.6e-64 E Glyoxalase-like domain
ACFBBGHA_02176 1.5e-36 yraG
ACFBBGHA_02177 6.4e-63 yraF M Spore coat protein
ACFBBGHA_02178 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
ACFBBGHA_02179 7.5e-26 yraE
ACFBBGHA_02180 2.5e-49 yraD M Spore coat protein
ACFBBGHA_02181 4.8e-46 yraB K helix_turn_helix, mercury resistance
ACFBBGHA_02182 2.1e-10 yphJ 4.1.1.44 S peroxiredoxin activity
ACFBBGHA_02183 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
ACFBBGHA_02184 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
ACFBBGHA_02185 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
ACFBBGHA_02186 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
ACFBBGHA_02187 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
ACFBBGHA_02188 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
ACFBBGHA_02189 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
ACFBBGHA_02190 0.0 levR K PTS system fructose IIA component
ACFBBGHA_02191 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
ACFBBGHA_02192 3.6e-106 yrhP E LysE type translocator
ACFBBGHA_02193 2e-149 yrhO K Archaeal transcriptional regulator TrmB
ACFBBGHA_02194 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_02195 3.8e-151 rsiV S Protein of unknown function (DUF3298)
ACFBBGHA_02196 0.0 yrhL I Acyltransferase family
ACFBBGHA_02197 3.3e-46 yrhK S YrhK-like protein
ACFBBGHA_02198 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
ACFBBGHA_02199 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
ACFBBGHA_02200 1.1e-95 yrhH Q methyltransferase
ACFBBGHA_02203 3e-142 focA P Formate nitrite
ACFBBGHA_02205 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
ACFBBGHA_02206 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
ACFBBGHA_02207 1.4e-78 yrhD S Protein of unknown function (DUF1641)
ACFBBGHA_02208 4.6e-35 yrhC S YrhC-like protein
ACFBBGHA_02209 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
ACFBBGHA_02210 1e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
ACFBBGHA_02211 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACFBBGHA_02212 2.2e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
ACFBBGHA_02213 1e-25 yrzA S Protein of unknown function (DUF2536)
ACFBBGHA_02214 1.6e-62 yrrS S Protein of unknown function (DUF1510)
ACFBBGHA_02215 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
ACFBBGHA_02216 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
ACFBBGHA_02217 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
ACFBBGHA_02218 2.7e-246 yegQ O COG0826 Collagenase and related proteases
ACFBBGHA_02219 2.9e-173 yegQ O Peptidase U32
ACFBBGHA_02220 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
ACFBBGHA_02221 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACFBBGHA_02222 1.2e-45 yrzB S Belongs to the UPF0473 family
ACFBBGHA_02223 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACFBBGHA_02224 1.7e-41 yrzL S Belongs to the UPF0297 family
ACFBBGHA_02225 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACFBBGHA_02226 2.7e-170 yrrI S AI-2E family transporter
ACFBBGHA_02227 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ACFBBGHA_02228 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
ACFBBGHA_02229 8e-109 gluC P ABC transporter
ACFBBGHA_02230 3.7e-106 glnP P ABC transporter
ACFBBGHA_02231 8e-08 S Protein of unknown function (DUF3918)
ACFBBGHA_02232 9.8e-31 yrzR
ACFBBGHA_02233 4.1e-83 yrrD S protein conserved in bacteria
ACFBBGHA_02234 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
ACFBBGHA_02235 1.4e-15 S COG0457 FOG TPR repeat
ACFBBGHA_02236 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
ACFBBGHA_02237 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
ACFBBGHA_02238 1.2e-70 cymR K Transcriptional regulator
ACFBBGHA_02239 4.8e-235 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
ACFBBGHA_02240 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
ACFBBGHA_02241 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACFBBGHA_02242 1.2e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
ACFBBGHA_02244 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
ACFBBGHA_02245 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
ACFBBGHA_02246 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACFBBGHA_02247 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACFBBGHA_02248 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
ACFBBGHA_02249 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
ACFBBGHA_02250 3.9e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
ACFBBGHA_02251 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACFBBGHA_02252 9.4e-49 yrzD S Post-transcriptional regulator
ACFBBGHA_02253 1.7e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ACFBBGHA_02254 2.9e-114 yrbG S membrane
ACFBBGHA_02255 1.2e-74 yrzE S Protein of unknown function (DUF3792)
ACFBBGHA_02256 1.1e-38 yajC U Preprotein translocase subunit YajC
ACFBBGHA_02257 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
ACFBBGHA_02258 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACFBBGHA_02259 2.6e-18 yrzS S Protein of unknown function (DUF2905)
ACFBBGHA_02260 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
ACFBBGHA_02261 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
ACFBBGHA_02262 4.8e-93 bofC S BofC C-terminal domain
ACFBBGHA_02263 5.3e-253 csbX EGP Major facilitator Superfamily
ACFBBGHA_02264 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
ACFBBGHA_02265 6.5e-119 yrzF T serine threonine protein kinase
ACFBBGHA_02267 1.5e-50 S Family of unknown function (DUF5412)
ACFBBGHA_02269 2e-261 alsT E Sodium alanine symporter
ACFBBGHA_02270 1.9e-127 yebC K transcriptional regulatory protein
ACFBBGHA_02271 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ACFBBGHA_02272 9.8e-158 safA M spore coat assembly protein SafA
ACFBBGHA_02273 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACFBBGHA_02274 4.7e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
ACFBBGHA_02275 4.4e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
ACFBBGHA_02276 3.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
ACFBBGHA_02277 2.3e-93 niaR S small molecule binding protein (contains 3H domain)
ACFBBGHA_02278 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
ACFBBGHA_02279 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
ACFBBGHA_02280 9.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACFBBGHA_02281 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
ACFBBGHA_02282 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
ACFBBGHA_02283 4.1e-56 ysxB J ribosomal protein
ACFBBGHA_02284 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
ACFBBGHA_02285 5.9e-160 spoIVFB S Stage IV sporulation protein
ACFBBGHA_02286 1.9e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
ACFBBGHA_02287 2.5e-144 minD D Belongs to the ParA family
ACFBBGHA_02288 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
ACFBBGHA_02289 1.4e-84 mreD M shape-determining protein
ACFBBGHA_02290 2.8e-157 mreC M Involved in formation and maintenance of cell shape
ACFBBGHA_02291 1.8e-184 mreB D Rod shape-determining protein MreB
ACFBBGHA_02292 5.9e-126 radC E Belongs to the UPF0758 family
ACFBBGHA_02293 2.8e-102 maf D septum formation protein Maf
ACFBBGHA_02294 2.4e-165 spoIIB S Sporulation related domain
ACFBBGHA_02295 2.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
ACFBBGHA_02296 4.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
ACFBBGHA_02297 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
ACFBBGHA_02298 1.6e-25
ACFBBGHA_02299 3.5e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACFBBGHA_02300 2.9e-222 spoVID M stage VI sporulation protein D
ACFBBGHA_02301 1.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
ACFBBGHA_02302 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
ACFBBGHA_02303 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
ACFBBGHA_02304 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
ACFBBGHA_02305 3.6e-146 hemX O cytochrome C
ACFBBGHA_02306 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACFBBGHA_02307 3.2e-89 ysxD
ACFBBGHA_02308 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
ACFBBGHA_02309 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ACFBBGHA_02310 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
ACFBBGHA_02311 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACFBBGHA_02312 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ACFBBGHA_02313 5.1e-187 ysoA H Tetratricopeptide repeat
ACFBBGHA_02314 2.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACFBBGHA_02315 1.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACFBBGHA_02316 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
ACFBBGHA_02317 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACFBBGHA_02318 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACFBBGHA_02319 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
ACFBBGHA_02320 0.0 ilvB 2.2.1.6 E Acetolactate synthase
ACFBBGHA_02322 2.3e-78 ysnE K acetyltransferase
ACFBBGHA_02323 5.1e-131 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ACFBBGHA_02324 2e-133 ysnF S protein conserved in bacteria
ACFBBGHA_02326 1.4e-92 ysnB S Phosphoesterase
ACFBBGHA_02327 2.2e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACFBBGHA_02328 5.3e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACFBBGHA_02329 4.2e-195 gerM S COG5401 Spore germination protein
ACFBBGHA_02330 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
ACFBBGHA_02331 8.7e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
ACFBBGHA_02332 3.3e-30 gerE K Transcriptional regulator
ACFBBGHA_02333 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
ACFBBGHA_02334 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
ACFBBGHA_02335 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
ACFBBGHA_02336 2.4e-107 sdhC C succinate dehydrogenase
ACFBBGHA_02337 1.2e-79 yslB S Protein of unknown function (DUF2507)
ACFBBGHA_02338 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
ACFBBGHA_02339 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
ACFBBGHA_02340 2e-52 trxA O Belongs to the thioredoxin family
ACFBBGHA_02341 1.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
ACFBBGHA_02343 4.2e-178 etfA C Electron transfer flavoprotein
ACFBBGHA_02344 1.2e-135 etfB C Electron transfer flavoprotein
ACFBBGHA_02345 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
ACFBBGHA_02346 2.7e-100 fadR K Transcriptional regulator
ACFBBGHA_02347 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
ACFBBGHA_02348 7.3e-68 yshE S membrane
ACFBBGHA_02349 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
ACFBBGHA_02350 0.0 polX L COG1796 DNA polymerase IV (family X)
ACFBBGHA_02351 1.3e-85 cvpA S membrane protein, required for colicin V production
ACFBBGHA_02352 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ACFBBGHA_02353 5.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACFBBGHA_02354 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ACFBBGHA_02355 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACFBBGHA_02356 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACFBBGHA_02357 5.8e-32 sspI S Belongs to the SspI family
ACFBBGHA_02358 6.3e-207 ysfB KT regulator
ACFBBGHA_02359 2.1e-263 glcD 1.1.3.15 C Glycolate oxidase subunit
ACFBBGHA_02360 6.8e-256 glcF C Glycolate oxidase
ACFBBGHA_02361 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
ACFBBGHA_02363 0.0 cstA T Carbon starvation protein
ACFBBGHA_02364 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
ACFBBGHA_02365 4.9e-143 araQ G transport system permease
ACFBBGHA_02366 4.2e-167 araP G carbohydrate transport
ACFBBGHA_02367 1.4e-253 araN G carbohydrate transport
ACFBBGHA_02368 7.5e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
ACFBBGHA_02369 1.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
ACFBBGHA_02370 2.4e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
ACFBBGHA_02371 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
ACFBBGHA_02372 1.3e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
ACFBBGHA_02373 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
ACFBBGHA_02374 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
ACFBBGHA_02375 9.2e-68 ysdB S Sigma-w pathway protein YsdB
ACFBBGHA_02376 8.3e-44 ysdA S Membrane
ACFBBGHA_02377 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACFBBGHA_02378 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
ACFBBGHA_02379 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACFBBGHA_02381 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
ACFBBGHA_02382 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
ACFBBGHA_02383 5.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
ACFBBGHA_02384 0.0 lytS 2.7.13.3 T Histidine kinase
ACFBBGHA_02385 4.7e-148 ysaA S HAD-hyrolase-like
ACFBBGHA_02386 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACFBBGHA_02388 1e-156 ytxC S YtxC-like family
ACFBBGHA_02389 4.9e-111 ytxB S SNARE associated Golgi protein
ACFBBGHA_02390 3e-173 dnaI L Primosomal protein DnaI
ACFBBGHA_02391 1.5e-264 dnaB L Membrane attachment protein
ACFBBGHA_02392 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACFBBGHA_02393 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACFBBGHA_02394 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ACFBBGHA_02395 9.9e-67 ytcD K Transcriptional regulator
ACFBBGHA_02396 2.1e-200 ytbD EGP Major facilitator Superfamily
ACFBBGHA_02397 8.9e-161 ytbE S reductase
ACFBBGHA_02398 5.4e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACFBBGHA_02399 1.1e-107 ytaF P Probably functions as a manganese efflux pump
ACFBBGHA_02400 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
ACFBBGHA_02401 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACFBBGHA_02402 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
ACFBBGHA_02403 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_02404 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
ACFBBGHA_02405 4.1e-242 icd 1.1.1.42 C isocitrate
ACFBBGHA_02406 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
ACFBBGHA_02407 2.3e-70 yeaL S membrane
ACFBBGHA_02408 9.9e-192 ytvI S sporulation integral membrane protein YtvI
ACFBBGHA_02409 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
ACFBBGHA_02410 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
ACFBBGHA_02411 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
ACFBBGHA_02412 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
ACFBBGHA_02413 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACFBBGHA_02414 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
ACFBBGHA_02415 0.0 dnaE 2.7.7.7 L DNA polymerase
ACFBBGHA_02416 3.2e-56 ytrH S Sporulation protein YtrH
ACFBBGHA_02417 3.4e-67 ytrI
ACFBBGHA_02418 9.2e-29
ACFBBGHA_02419 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
ACFBBGHA_02420 2.4e-47 ytpI S YtpI-like protein
ACFBBGHA_02421 8e-241 ytoI K transcriptional regulator containing CBS domains
ACFBBGHA_02422 1.4e-156 ytnM S membrane transporter protein
ACFBBGHA_02423 1.6e-235 ytnL 3.5.1.47 E hydrolase activity
ACFBBGHA_02424 4.1e-127 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
ACFBBGHA_02425 3.5e-252 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACFBBGHA_02426 6e-45 ytnI O COG0695 Glutaredoxin and related proteins
ACFBBGHA_02427 2.6e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACFBBGHA_02428 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
ACFBBGHA_02429 9.3e-119 tcyM U Binding-protein-dependent transport system inner membrane component
ACFBBGHA_02430 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
ACFBBGHA_02431 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
ACFBBGHA_02432 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
ACFBBGHA_02433 4.3e-100 ytmI K Acetyltransferase (GNAT) domain
ACFBBGHA_02434 1.2e-171 ytlI K LysR substrate binding domain
ACFBBGHA_02435 1.7e-130 ytkL S Belongs to the UPF0173 family
ACFBBGHA_02436 2.5e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_02438 4.4e-266 argH 4.3.2.1 E argininosuccinate lyase
ACFBBGHA_02439 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
ACFBBGHA_02440 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
ACFBBGHA_02441 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACFBBGHA_02442 5.9e-164 ytxK 2.1.1.72 L DNA methylase
ACFBBGHA_02443 7.1e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACFBBGHA_02444 2.3e-70 ytfJ S Sporulation protein YtfJ
ACFBBGHA_02445 1.6e-115 ytfI S Protein of unknown function (DUF2953)
ACFBBGHA_02446 2.5e-86 yteJ S RDD family
ACFBBGHA_02447 8.7e-179 sppA OU signal peptide peptidase SppA
ACFBBGHA_02448 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACFBBGHA_02449 0.0 ytcJ S amidohydrolase
ACFBBGHA_02450 1.7e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
ACFBBGHA_02451 2e-29 sspB S spore protein
ACFBBGHA_02452 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACFBBGHA_02453 1.2e-208 iscS2 2.8.1.7 E Cysteine desulfurase
ACFBBGHA_02454 1.4e-237 brnQ E Component of the transport system for branched-chain amino acids
ACFBBGHA_02455 7.8e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ACFBBGHA_02456 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
ACFBBGHA_02457 3.4e-109 yttP K Transcriptional regulator
ACFBBGHA_02458 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
ACFBBGHA_02459 2.4e-311 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
ACFBBGHA_02460 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACFBBGHA_02462 2.3e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACFBBGHA_02463 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
ACFBBGHA_02464 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
ACFBBGHA_02465 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
ACFBBGHA_02466 5.4e-225 acuC BQ histone deacetylase
ACFBBGHA_02467 1.4e-125 motS N Flagellar motor protein
ACFBBGHA_02468 6e-146 motA N flagellar motor
ACFBBGHA_02469 3.8e-182 ccpA K catabolite control protein A
ACFBBGHA_02470 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
ACFBBGHA_02471 1.1e-53 ytxJ O Protein of unknown function (DUF2847)
ACFBBGHA_02472 6.6e-17 ytxH S COG4980 Gas vesicle protein
ACFBBGHA_02473 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
ACFBBGHA_02474 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
ACFBBGHA_02475 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
ACFBBGHA_02476 1.4e-107 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
ACFBBGHA_02477 9.8e-149 ytpQ S Belongs to the UPF0354 family
ACFBBGHA_02478 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
ACFBBGHA_02479 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
ACFBBGHA_02480 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
ACFBBGHA_02481 1.1e-50 ytzB S small secreted protein
ACFBBGHA_02482 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
ACFBBGHA_02483 6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
ACFBBGHA_02484 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
ACFBBGHA_02485 2e-45 ytzH S YtzH-like protein
ACFBBGHA_02486 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
ACFBBGHA_02487 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
ACFBBGHA_02488 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
ACFBBGHA_02489 1.3e-165 ytlQ
ACFBBGHA_02490 2.6e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ACFBBGHA_02491 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ACFBBGHA_02492 2.3e-270 pepV 3.5.1.18 E Dipeptidase
ACFBBGHA_02493 2.1e-225 pbuO S permease
ACFBBGHA_02494 4.6e-200 ythQ U Bacterial ABC transporter protein EcsB
ACFBBGHA_02495 4.8e-131 ythP V ABC transporter
ACFBBGHA_02496 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
ACFBBGHA_02497 4.8e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
ACFBBGHA_02498 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ACFBBGHA_02499 8.2e-232 ytfP S HI0933-like protein
ACFBBGHA_02500 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
ACFBBGHA_02501 3.1e-26 yteV S Sporulation protein Cse60
ACFBBGHA_02502 5.9e-115 yteU S Integral membrane protein
ACFBBGHA_02503 8.3e-248 yteT S Oxidoreductase family, C-terminal alpha/beta domain
ACFBBGHA_02504 3e-72 yteS G transport
ACFBBGHA_02505 5.2e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
ACFBBGHA_02506 1.1e-170 lplB G COG4209 ABC-type polysaccharide transport system, permease component
ACFBBGHA_02507 0.0 ytdP K Transcriptional regulator
ACFBBGHA_02508 1.2e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
ACFBBGHA_02509 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
ACFBBGHA_02510 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
ACFBBGHA_02511 2.7e-224 bioI 1.14.14.46 C Cytochrome P450
ACFBBGHA_02512 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACFBBGHA_02513 1.6e-123 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACFBBGHA_02514 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
ACFBBGHA_02515 3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
ACFBBGHA_02516 3.2e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
ACFBBGHA_02517 7.8e-171 ytaP S Acetyl xylan esterase (AXE1)
ACFBBGHA_02518 1.9e-189 msmR K Transcriptional regulator
ACFBBGHA_02519 1.2e-246 msmE G Bacterial extracellular solute-binding protein
ACFBBGHA_02520 1.4e-167 amyD P ABC transporter
ACFBBGHA_02521 3.1e-142 amyC P ABC transporter (permease)
ACFBBGHA_02522 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
ACFBBGHA_02523 2.1e-51 ytwF P Sulfurtransferase
ACFBBGHA_02524 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
ACFBBGHA_02525 7.7e-55 ytvB S Protein of unknown function (DUF4257)
ACFBBGHA_02526 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
ACFBBGHA_02527 3e-210 yttB EGP Major facilitator Superfamily
ACFBBGHA_02528 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
ACFBBGHA_02529 0.0 bceB V ABC transporter (permease)
ACFBBGHA_02530 1.1e-138 bceA V ABC transporter, ATP-binding protein
ACFBBGHA_02531 1.6e-185 T PhoQ Sensor
ACFBBGHA_02532 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_02533 5.5e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
ACFBBGHA_02534 3.1e-127 ytrE V ABC transporter, ATP-binding protein
ACFBBGHA_02535 2e-140
ACFBBGHA_02536 8.3e-150 P ABC-2 family transporter protein
ACFBBGHA_02537 4.2e-161 ytrB P abc transporter atp-binding protein
ACFBBGHA_02538 5.1e-66 ytrA K GntR family transcriptional regulator
ACFBBGHA_02540 6.7e-41 ytzC S Protein of unknown function (DUF2524)
ACFBBGHA_02541 8.1e-190 yhcC S Fe-S oxidoreductase
ACFBBGHA_02542 2.2e-105 ytqB J Putative rRNA methylase
ACFBBGHA_02543 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
ACFBBGHA_02544 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
ACFBBGHA_02545 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACFBBGHA_02546 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
ACFBBGHA_02547 0.0 asnB 6.3.5.4 E Asparagine synthase
ACFBBGHA_02548 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACFBBGHA_02549 2.6e-310 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ACFBBGHA_02550 1.2e-38 ytmB S Protein of unknown function (DUF2584)
ACFBBGHA_02551 1.6e-148 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
ACFBBGHA_02552 4e-187 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
ACFBBGHA_02553 1.4e-144 ytlC P ABC transporter
ACFBBGHA_02554 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
ACFBBGHA_02555 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
ACFBBGHA_02556 5.4e-63 ytkC S Bacteriophage holin family
ACFBBGHA_02557 2.1e-76 dps P Belongs to the Dps family
ACFBBGHA_02559 5.3e-72 ytkA S YtkA-like
ACFBBGHA_02560 4.8e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
ACFBBGHA_02561 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
ACFBBGHA_02562 3.6e-41 rpmE2 J Ribosomal protein L31
ACFBBGHA_02563 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
ACFBBGHA_02564 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
ACFBBGHA_02565 1.1e-24 S Domain of Unknown Function (DUF1540)
ACFBBGHA_02566 9.7e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
ACFBBGHA_02567 3.3e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
ACFBBGHA_02568 8.6e-139 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
ACFBBGHA_02569 6.7e-170 troA P Belongs to the bacterial solute-binding protein 9 family
ACFBBGHA_02570 1.2e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
ACFBBGHA_02571 8.8e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
ACFBBGHA_02572 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ACFBBGHA_02573 3.3e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
ACFBBGHA_02574 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ACFBBGHA_02575 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
ACFBBGHA_02576 5.7e-132 dksA T COG1734 DnaK suppressor protein
ACFBBGHA_02577 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
ACFBBGHA_02578 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACFBBGHA_02579 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
ACFBBGHA_02580 1.4e-234 ytcC M Glycosyltransferase Family 4
ACFBBGHA_02582 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
ACFBBGHA_02583 1.8e-217 cotSA M Glycosyl transferases group 1
ACFBBGHA_02584 1.1e-205 cotI S Spore coat protein
ACFBBGHA_02585 1.3e-76 tspO T membrane
ACFBBGHA_02586 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
ACFBBGHA_02587 7.6e-285 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
ACFBBGHA_02588 1.4e-176 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
ACFBBGHA_02589 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACFBBGHA_02590 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ACFBBGHA_02599 7.8e-08
ACFBBGHA_02600 1.3e-09
ACFBBGHA_02607 2e-08
ACFBBGHA_02611 6.7e-167 ygxA S Nucleotidyltransferase-like
ACFBBGHA_02612 9.5e-56 ygzB S UPF0295 protein
ACFBBGHA_02613 4e-80 perR P Belongs to the Fur family
ACFBBGHA_02614 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
ACFBBGHA_02615 1.4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
ACFBBGHA_02616 8.7e-180 ygaE S Membrane
ACFBBGHA_02617 1.8e-301 ygaD V ABC transporter
ACFBBGHA_02618 1.3e-104 ygaC J Belongs to the UPF0374 family
ACFBBGHA_02619 1.5e-37 ygaB S YgaB-like protein
ACFBBGHA_02620 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
ACFBBGHA_02621 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_02622 6.9e-36 yfhS
ACFBBGHA_02623 9.5e-210 mutY L A G-specific
ACFBBGHA_02624 1.2e-185 yfhP S membrane-bound metal-dependent
ACFBBGHA_02625 0.0 yfhO S Bacterial membrane protein YfhO
ACFBBGHA_02626 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ACFBBGHA_02627 1.3e-170 yfhM S Alpha beta hydrolase
ACFBBGHA_02628 1e-47 yfhL S SdpI/YhfL protein family
ACFBBGHA_02629 1.3e-90 batE T Bacterial SH3 domain homologues
ACFBBGHA_02630 1.3e-44 yfhJ S WVELL protein
ACFBBGHA_02631 6.2e-20 sspK S reproduction
ACFBBGHA_02632 2.1e-208 yfhI EGP Major facilitator Superfamily
ACFBBGHA_02634 9.7e-52 yfhH S Protein of unknown function (DUF1811)
ACFBBGHA_02635 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
ACFBBGHA_02636 3.5e-171 yfhF S nucleoside-diphosphate sugar epimerase
ACFBBGHA_02638 2.1e-25 yfhD S YfhD-like protein
ACFBBGHA_02639 3.9e-107 yfhC C nitroreductase
ACFBBGHA_02640 1.8e-167 yfhB 5.3.3.17 S PhzF family
ACFBBGHA_02641 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_02642 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_02643 3.9e-176 yfiY P ABC transporter substrate-binding protein
ACFBBGHA_02644 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ACFBBGHA_02645 4.9e-79 yfiV K transcriptional
ACFBBGHA_02646 4.2e-281 yfiU EGP Major facilitator Superfamily
ACFBBGHA_02647 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
ACFBBGHA_02648 5.9e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
ACFBBGHA_02649 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
ACFBBGHA_02650 8.3e-99 padR K transcriptional
ACFBBGHA_02651 1.4e-204 V COG0842 ABC-type multidrug transport system, permease component
ACFBBGHA_02652 5.8e-206 V ABC-2 family transporter protein
ACFBBGHA_02653 1.3e-165 V ABC transporter, ATP-binding protein
ACFBBGHA_02654 2.1e-112 KT LuxR family transcriptional regulator
ACFBBGHA_02655 1.8e-212 yxjM T Histidine kinase
ACFBBGHA_02657 2.8e-162 yfiE 1.13.11.2 S glyoxalase
ACFBBGHA_02658 6.4e-64 mhqP S DoxX
ACFBBGHA_02659 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
ACFBBGHA_02660 8.4e-307 yfiB3 V ABC transporter
ACFBBGHA_02661 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ACFBBGHA_02662 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
ACFBBGHA_02663 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
ACFBBGHA_02664 3.3e-44 yfjA S Belongs to the WXG100 family
ACFBBGHA_02665 6e-190 yfjB
ACFBBGHA_02666 4.1e-144 yfjC
ACFBBGHA_02667 3.4e-100 yfjD S Family of unknown function (DUF5381)
ACFBBGHA_02668 2.5e-79 S Family of unknown function (DUF5381)
ACFBBGHA_02669 4e-56 yfjF S UPF0060 membrane protein
ACFBBGHA_02670 1.2e-25 sspH S Belongs to the SspH family
ACFBBGHA_02671 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
ACFBBGHA_02672 9.5e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
ACFBBGHA_02673 6e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
ACFBBGHA_02674 3.6e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
ACFBBGHA_02675 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
ACFBBGHA_02676 1e-29 yfjL
ACFBBGHA_02677 6.4e-81 yfjM S Psort location Cytoplasmic, score
ACFBBGHA_02678 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACFBBGHA_02679 3.9e-44 S YfzA-like protein
ACFBBGHA_02680 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACFBBGHA_02681 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACFBBGHA_02682 1.7e-184 corA P Mediates influx of magnesium ions
ACFBBGHA_02683 2.3e-148 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
ACFBBGHA_02684 2.6e-154 pdaA G deacetylase
ACFBBGHA_02685 1.1e-26 yfjT
ACFBBGHA_02686 5.4e-222 yfkA S YfkB-like domain
ACFBBGHA_02687 6e-149 yfkC M Mechanosensitive ion channel
ACFBBGHA_02688 1.2e-146 yfkD S YfkD-like protein
ACFBBGHA_02689 6.1e-183 cax P COG0387 Ca2 H antiporter
ACFBBGHA_02690 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
ACFBBGHA_02691 9.7e-144 yihY S Belongs to the UPF0761 family
ACFBBGHA_02692 2.4e-50 yfkI S gas vesicle protein
ACFBBGHA_02693 3e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACFBBGHA_02694 2.1e-29 yfkK S Belongs to the UPF0435 family
ACFBBGHA_02695 2.6e-206 ydiM EGP Major facilitator Superfamily
ACFBBGHA_02696 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
ACFBBGHA_02697 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
ACFBBGHA_02698 1.8e-124 yfkO C nitroreductase
ACFBBGHA_02699 1.8e-133 treR K transcriptional
ACFBBGHA_02700 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
ACFBBGHA_02701 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ACFBBGHA_02702 3.8e-282 yfkQ EG Spore germination protein
ACFBBGHA_02703 5.1e-207 yfkR S spore germination
ACFBBGHA_02705 1.3e-193 E Spore germination protein
ACFBBGHA_02706 2.2e-252 agcS_1 E Sodium alanine symporter
ACFBBGHA_02707 6e-67 yhdN S Domain of unknown function (DUF1992)
ACFBBGHA_02708 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ACFBBGHA_02709 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
ACFBBGHA_02710 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
ACFBBGHA_02711 5.3e-50 yflH S Protein of unknown function (DUF3243)
ACFBBGHA_02712 1.6e-18 yflI
ACFBBGHA_02713 8.9e-18 yflJ S Protein of unknown function (DUF2639)
ACFBBGHA_02714 1.7e-122 yflK S protein conserved in bacteria
ACFBBGHA_02715 1.9e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
ACFBBGHA_02716 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
ACFBBGHA_02717 1.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
ACFBBGHA_02718 8.5e-227 citM C Citrate transporter
ACFBBGHA_02719 3.7e-179 yflP S Tripartite tricarboxylate transporter family receptor
ACFBBGHA_02720 2.9e-117 citT T response regulator
ACFBBGHA_02721 5.7e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ACFBBGHA_02722 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
ACFBBGHA_02723 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
ACFBBGHA_02724 7.6e-58 yflT S Heat induced stress protein YflT
ACFBBGHA_02725 5e-24 S Protein of unknown function (DUF3212)
ACFBBGHA_02726 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
ACFBBGHA_02727 5.3e-168 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_02728 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_02729 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
ACFBBGHA_02730 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
ACFBBGHA_02731 2.2e-213 G Major Facilitator Superfamily
ACFBBGHA_02732 2.5e-189 yfmJ S N-terminal domain of oxidoreductase
ACFBBGHA_02733 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
ACFBBGHA_02734 2.2e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
ACFBBGHA_02735 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ACFBBGHA_02736 1.5e-209 yfmO EGP Major facilitator Superfamily
ACFBBGHA_02737 1.4e-69 yfmP K transcriptional
ACFBBGHA_02738 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
ACFBBGHA_02739 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
ACFBBGHA_02740 1.1e-113 yfmS NT chemotaxis protein
ACFBBGHA_02741 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ACFBBGHA_02742 1.4e-240 yfnA E amino acid
ACFBBGHA_02743 1.1e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
ACFBBGHA_02744 1.7e-205 fsr P COG0477 Permeases of the major facilitator superfamily
ACFBBGHA_02745 1.2e-187 yfnD M Nucleotide-diphospho-sugar transferase
ACFBBGHA_02746 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
ACFBBGHA_02747 1.9e-180 yfnF M Nucleotide-diphospho-sugar transferase
ACFBBGHA_02748 4.1e-186 yfnG 4.2.1.45 M dehydratase
ACFBBGHA_02749 8.7e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
ACFBBGHA_02750 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ACFBBGHA_02751 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
ACFBBGHA_02752 3.6e-199 yetN S Protein of unknown function (DUF3900)
ACFBBGHA_02753 2.7e-108 S Uncharacterised protein conserved in bacteria (DUF2326)
ACFBBGHA_02754 4.4e-21
ACFBBGHA_02755 6.8e-75
ACFBBGHA_02756 2.4e-30 yetM CH FAD binding domain
ACFBBGHA_02757 5.3e-105 yetJ S Belongs to the BI1 family
ACFBBGHA_02758 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
ACFBBGHA_02759 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
ACFBBGHA_02760 2.2e-34
ACFBBGHA_02761 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ACFBBGHA_02762 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
ACFBBGHA_02763 4e-122 yetF S membrane
ACFBBGHA_02764 2.2e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
ACFBBGHA_02765 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
ACFBBGHA_02766 2.1e-174 lplB G COG4209 ABC-type polysaccharide transport system, permease component
ACFBBGHA_02767 3.7e-290 lplA G Bacterial extracellular solute-binding protein
ACFBBGHA_02768 0.0 yetA
ACFBBGHA_02769 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
ACFBBGHA_02770 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
ACFBBGHA_02771 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
ACFBBGHA_02772 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
ACFBBGHA_02773 6.3e-111 yesV S Protein of unknown function, DUF624
ACFBBGHA_02774 4.6e-128 yesU S Domain of unknown function (DUF1961)
ACFBBGHA_02775 7.4e-129 E GDSL-like Lipase/Acylhydrolase
ACFBBGHA_02776 0.0 yesS K Transcriptional regulator
ACFBBGHA_02777 7.8e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
ACFBBGHA_02778 1e-162 yesQ P Binding-protein-dependent transport system inner membrane component
ACFBBGHA_02779 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
ACFBBGHA_02780 1.1e-247 yesO G Bacterial extracellular solute-binding protein
ACFBBGHA_02781 2.8e-202 yesN K helix_turn_helix, arabinose operon control protein
ACFBBGHA_02782 0.0 yesM 2.7.13.3 T Histidine kinase
ACFBBGHA_02783 9.2e-102 yesL S Protein of unknown function, DUF624
ACFBBGHA_02785 1.8e-101 yesJ K Acetyltransferase (GNAT) family
ACFBBGHA_02786 5.2e-104 cotJC P Spore Coat
ACFBBGHA_02787 1.5e-45 cotJB S CotJB protein
ACFBBGHA_02788 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
ACFBBGHA_02789 1.3e-151 yesF GM NAD(P)H-binding
ACFBBGHA_02790 9.7e-82 yesE S SnoaL-like domain
ACFBBGHA_02791 1.2e-103 dhaR3 K Transcriptional regulator
ACFBBGHA_02793 2.7e-126 yeeN K transcriptional regulatory protein
ACFBBGHA_02795 4.3e-211 S Tetratricopeptide repeat
ACFBBGHA_02796 1.8e-39
ACFBBGHA_02797 6.9e-176 3.4.24.40 CO amine dehydrogenase activity
ACFBBGHA_02798 8.1e-186 yobL S Bacterial EndoU nuclease
ACFBBGHA_02799 1.3e-42 S Immunity protein 22
ACFBBGHA_02801 1.2e-99 S response regulator aspartate phosphatase
ACFBBGHA_02803 0.0 K SIR2-like domain
ACFBBGHA_02804 5e-20
ACFBBGHA_02805 2.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACFBBGHA_02806 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
ACFBBGHA_02807 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACFBBGHA_02808 1.5e-147 yerO K Transcriptional regulator
ACFBBGHA_02809 6.8e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACFBBGHA_02810 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
ACFBBGHA_02811 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACFBBGHA_02812 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACFBBGHA_02813 6.1e-123 sapB S MgtC SapB transporter
ACFBBGHA_02814 3.5e-196 yerI S homoserine kinase type II (protein kinase fold)
ACFBBGHA_02816 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
ACFBBGHA_02817 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACFBBGHA_02818 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
ACFBBGHA_02819 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ACFBBGHA_02820 6.7e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
ACFBBGHA_02821 2.4e-50 yerC S protein conserved in bacteria
ACFBBGHA_02822 6.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
ACFBBGHA_02823 0.0 yerA 3.5.4.2 F adenine deaminase
ACFBBGHA_02824 2.7e-27 S Protein of unknown function (DUF2892)
ACFBBGHA_02825 2.3e-229 yjeH E Amino acid permease
ACFBBGHA_02826 7e-43 K helix_turn_helix ASNC type
ACFBBGHA_02827 2e-233 purD 6.3.4.13 F Belongs to the GARS family
ACFBBGHA_02828 6e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
ACFBBGHA_02829 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACFBBGHA_02830 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
ACFBBGHA_02831 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACFBBGHA_02832 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACFBBGHA_02833 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACFBBGHA_02834 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACFBBGHA_02835 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
ACFBBGHA_02836 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACFBBGHA_02837 1e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACFBBGHA_02838 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACFBBGHA_02839 1.8e-27 yebG S NETI protein
ACFBBGHA_02840 4e-93 yebE S UPF0316 protein
ACFBBGHA_02842 2.3e-118 yebC M Membrane
ACFBBGHA_02843 1.1e-210 pbuG S permease
ACFBBGHA_02844 1.2e-245 S Domain of unknown function (DUF4179)
ACFBBGHA_02845 4.9e-88 K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_02846 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
ACFBBGHA_02847 0.0 yebA E COG1305 Transglutaminase-like enzymes
ACFBBGHA_02848 6.4e-221 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
ACFBBGHA_02849 1.7e-176 yeaC S COG0714 MoxR-like ATPases
ACFBBGHA_02850 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACFBBGHA_02851 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
ACFBBGHA_02852 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
ACFBBGHA_02853 3.3e-175 yeaA S Protein of unknown function (DUF4003)
ACFBBGHA_02854 7.6e-157 ydjP I Alpha/beta hydrolase family
ACFBBGHA_02855 1.4e-34 ydjO S Cold-inducible protein YdjO
ACFBBGHA_02857 1e-153 ydjN U Involved in the tonB-independent uptake of proteins
ACFBBGHA_02858 2.9e-63 ydjM M Lytic transglycolase
ACFBBGHA_02859 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
ACFBBGHA_02860 1.9e-256 iolT EGP Major facilitator Superfamily
ACFBBGHA_02861 2.6e-194 S Ion transport 2 domain protein
ACFBBGHA_02862 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
ACFBBGHA_02863 1.2e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
ACFBBGHA_02864 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACFBBGHA_02865 5.6e-113 pspA KT Phage shock protein A
ACFBBGHA_02866 3.4e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
ACFBBGHA_02867 1.1e-253 gutA G MFS/sugar transport protein
ACFBBGHA_02868 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
ACFBBGHA_02869 0.0 K NB-ARC domain
ACFBBGHA_02870 1.1e-154 ydjC S Abhydrolase domain containing 18
ACFBBGHA_02871 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
ACFBBGHA_02872 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACFBBGHA_02873 7.9e-129 ydiL S CAAX protease self-immunity
ACFBBGHA_02874 2.9e-27 ydiK S Domain of unknown function (DUF4305)
ACFBBGHA_02875 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACFBBGHA_02876 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
ACFBBGHA_02877 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ACFBBGHA_02878 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
ACFBBGHA_02879 0.0 ydiF S ABC transporter
ACFBBGHA_02880 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACFBBGHA_02881 2.4e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
ACFBBGHA_02882 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
ACFBBGHA_02883 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
ACFBBGHA_02884 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACFBBGHA_02886 7.8e-08
ACFBBGHA_02887 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACFBBGHA_02888 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACFBBGHA_02889 1.8e-37 yaaB S Domain of unknown function (DUF370)
ACFBBGHA_02890 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACFBBGHA_02891 2.4e-33 yaaA S S4 domain
ACFBBGHA_02892 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
ACFBBGHA_02893 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACFBBGHA_02894 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
ACFBBGHA_02895 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ACFBBGHA_02896 6.5e-108 jag S single-stranded nucleic acid binding R3H
ACFBBGHA_02897 1.1e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACFBBGHA_02898 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
ACFBBGHA_02899 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
ACFBBGHA_02900 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
ACFBBGHA_02901 1.1e-72 S Bacterial PH domain
ACFBBGHA_02902 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
ACFBBGHA_02903 3.9e-148 spo0J K Belongs to the ParB family
ACFBBGHA_02904 2.1e-111 yyaC S Sporulation protein YyaC
ACFBBGHA_02905 8.1e-177 yyaD S Membrane
ACFBBGHA_02906 2.3e-33 yyzM S protein conserved in bacteria
ACFBBGHA_02907 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ACFBBGHA_02908 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
ACFBBGHA_02909 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
ACFBBGHA_02910 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
ACFBBGHA_02911 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACFBBGHA_02912 1.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
ACFBBGHA_02913 1.5e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
ACFBBGHA_02914 1.9e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ACFBBGHA_02915 8.1e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
ACFBBGHA_02916 6.1e-244 EGP Major facilitator superfamily
ACFBBGHA_02917 4e-167 yyaK S CAAX protease self-immunity
ACFBBGHA_02918 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
ACFBBGHA_02919 4.4e-161 yyaM EG EamA-like transporter family
ACFBBGHA_02920 1.5e-60 yyaN K MerR HTH family regulatory protein
ACFBBGHA_02921 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
ACFBBGHA_02922 6.6e-246 tetL EGP Major facilitator Superfamily
ACFBBGHA_02923 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
ACFBBGHA_02924 1.3e-65 yyaQ S YjbR
ACFBBGHA_02925 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
ACFBBGHA_02926 5.5e-96 yyaS S Membrane
ACFBBGHA_02927 2e-71 yjcF S Acetyltransferase (GNAT) domain
ACFBBGHA_02928 5.6e-77 yybA 2.3.1.57 K transcriptional
ACFBBGHA_02929 7.3e-126 S Metallo-beta-lactamase superfamily
ACFBBGHA_02930 2.3e-73 yybC
ACFBBGHA_02931 5.5e-77 yjcF S Acetyltransferase (GNAT) domain
ACFBBGHA_02932 6.9e-164 yybE K Transcriptional regulator
ACFBBGHA_02933 1.8e-215 ynfM EGP Major facilitator Superfamily
ACFBBGHA_02934 4e-121 yybG S Pentapeptide repeat-containing protein
ACFBBGHA_02935 2.9e-66 yybH S SnoaL-like domain
ACFBBGHA_02936 1.1e-123
ACFBBGHA_02937 7.4e-111 K TipAS antibiotic-recognition domain
ACFBBGHA_02938 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
ACFBBGHA_02940 1.6e-60
ACFBBGHA_02941 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
ACFBBGHA_02942 7.5e-67 ydeP3 K Transcriptional regulator
ACFBBGHA_02943 3.9e-84 cotF M Spore coat protein
ACFBBGHA_02945 2.9e-160 yybS S membrane
ACFBBGHA_02946 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
ACFBBGHA_02947 2.2e-73 rplI J binds to the 23S rRNA
ACFBBGHA_02948 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ACFBBGHA_02949 2.5e-220 yeaN P COG2807 Cyanate permease
ACFBBGHA_02950 1.9e-15 yycC K YycC-like protein
ACFBBGHA_02952 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
ACFBBGHA_02953 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
ACFBBGHA_02954 4.4e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ACFBBGHA_02955 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACFBBGHA_02960 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_02961 0.0 vicK 2.7.13.3 T Histidine kinase
ACFBBGHA_02962 3.4e-258 yycH S protein conserved in bacteria
ACFBBGHA_02963 1.8e-153 yycI S protein conserved in bacteria
ACFBBGHA_02964 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
ACFBBGHA_02965 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACFBBGHA_02966 2.7e-24 S Peptidase propeptide and YPEB domain
ACFBBGHA_02967 4e-74 S Peptidase propeptide and YPEB domain
ACFBBGHA_02968 1.5e-94 K PFAM response regulator receiver
ACFBBGHA_02969 4.4e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
ACFBBGHA_02970 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
ACFBBGHA_02971 1.2e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
ACFBBGHA_02972 4.8e-260 rocE E amino acid
ACFBBGHA_02973 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
ACFBBGHA_02975 1.2e-186 S aspartate phosphatase
ACFBBGHA_02976 2.2e-84 yycN 2.3.1.128 K Acetyltransferase
ACFBBGHA_02977 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
ACFBBGHA_02978 3.6e-213 yycP
ACFBBGHA_02979 9.7e-31 yycQ S Protein of unknown function (DUF2651)
ACFBBGHA_02981 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
ACFBBGHA_02982 4.4e-68
ACFBBGHA_02983 1.1e-09 S YyzF-like protein
ACFBBGHA_02984 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACFBBGHA_02985 1.2e-19
ACFBBGHA_02986 7.1e-109 L reverse transcriptase
ACFBBGHA_02987 7.6e-118 atmc2 S Caspase domain
ACFBBGHA_02988 3e-42 S MazG-like family
ACFBBGHA_02989 3.9e-245 L Uncharacterized conserved protein (DUF2075)
ACFBBGHA_02990 0.0 L AAA domain
ACFBBGHA_02991 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
ACFBBGHA_02992 8.4e-12
ACFBBGHA_02993 9.3e-127 yydK K Transcriptional regulator
ACFBBGHA_02994 4.1e-12 bglF G phosphotransferase system
ACFBBGHA_02995 1.2e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACFBBGHA_02996 1.6e-188 wgaE S Polysaccharide pyruvyl transferase
ACFBBGHA_02997 1.9e-286 ahpF O Alkyl hydroperoxide reductase
ACFBBGHA_02998 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
ACFBBGHA_02999 2.7e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ACFBBGHA_03000 3.8e-230 gntP EG COG2610 H gluconate symporter and related permeases
ACFBBGHA_03001 8.6e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
ACFBBGHA_03002 1.1e-125 gntR K transcriptional
ACFBBGHA_03003 8.6e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
ACFBBGHA_03004 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
ACFBBGHA_03005 1.3e-117 yxaC M effector of murein hydrolase
ACFBBGHA_03006 5.2e-50 S LrgA family
ACFBBGHA_03007 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
ACFBBGHA_03008 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_03009 2.1e-100 yxaF K Transcriptional regulator
ACFBBGHA_03010 1.1e-192 yxaG 1.13.11.24 S AraC-like ligand binding domain
ACFBBGHA_03011 1.2e-227 P Protein of unknown function (DUF418)
ACFBBGHA_03012 1.1e-75 yxaI S membrane protein domain
ACFBBGHA_03013 3.5e-65 S Family of unknown function (DUF5391)
ACFBBGHA_03014 4.4e-92 S PQQ-like domain
ACFBBGHA_03015 7.6e-214 yxaM U MFS_1 like family
ACFBBGHA_03016 0.0 asnB 6.3.5.4 E Asparagine synthase
ACFBBGHA_03017 1.1e-86 yxnB
ACFBBGHA_03018 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
ACFBBGHA_03019 1.3e-126 yxbB Q Met-10+ like-protein
ACFBBGHA_03020 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
ACFBBGHA_03021 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
ACFBBGHA_03022 5.2e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
ACFBBGHA_03023 9.1e-209 yxbF K Bacterial regulatory proteins, tetR family
ACFBBGHA_03024 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
ACFBBGHA_03026 0.0 htpG O Molecular chaperone. Has ATPase activity
ACFBBGHA_03027 1.6e-244 csbC EGP Major facilitator Superfamily
ACFBBGHA_03028 4.1e-47 yxcD S Protein of unknown function (DUF2653)
ACFBBGHA_03030 8.3e-176 iolS C Aldo keto reductase
ACFBBGHA_03031 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
ACFBBGHA_03032 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ACFBBGHA_03033 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
ACFBBGHA_03034 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
ACFBBGHA_03035 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
ACFBBGHA_03036 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
ACFBBGHA_03037 6.6e-235 iolF EGP Major facilitator Superfamily
ACFBBGHA_03038 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
ACFBBGHA_03039 8.6e-167 iolH G Xylose isomerase-like TIM barrel
ACFBBGHA_03040 2.1e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
ACFBBGHA_03041 1e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
ACFBBGHA_03042 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_03043 4e-181 T PhoQ Sensor
ACFBBGHA_03044 2.7e-140 yxdL V ABC transporter, ATP-binding protein
ACFBBGHA_03045 0.0 yxdM V ABC transporter (permease)
ACFBBGHA_03046 1.5e-58 yxeA S Protein of unknown function (DUF1093)
ACFBBGHA_03047 2.1e-174 fhuD P ABC transporter
ACFBBGHA_03048 1.4e-68
ACFBBGHA_03049 5.6e-16 yxeD
ACFBBGHA_03050 1.3e-20 yxeE
ACFBBGHA_03053 1.8e-150 yidA S hydrolases of the HAD superfamily
ACFBBGHA_03054 2.5e-186 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
ACFBBGHA_03056 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACFBBGHA_03057 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ACFBBGHA_03058 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
ACFBBGHA_03059 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
ACFBBGHA_03060 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
ACFBBGHA_03061 1.4e-212 yxeP 3.5.1.47 E hydrolase activity
ACFBBGHA_03062 2.4e-248 yxeQ S MmgE/PrpD family
ACFBBGHA_03063 1.9e-195 eutH E Ethanolamine utilisation protein, EutH
ACFBBGHA_03064 7.4e-152 yxxB S Domain of Unknown Function (DUF1206)
ACFBBGHA_03065 5.1e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
ACFBBGHA_03066 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACFBBGHA_03067 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACFBBGHA_03068 2.1e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
ACFBBGHA_03069 6.8e-251 lysP E amino acid
ACFBBGHA_03070 1.5e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
ACFBBGHA_03071 5.9e-233 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
ACFBBGHA_03072 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACFBBGHA_03073 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
ACFBBGHA_03074 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
ACFBBGHA_03075 1.8e-278 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
ACFBBGHA_03076 3.6e-166 L Protein of unknown function (DUF2726)
ACFBBGHA_03077 3.5e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
ACFBBGHA_03078 0.0 L HKD family nuclease
ACFBBGHA_03079 4.6e-21 S Domain of unknown function (DUF5082)
ACFBBGHA_03080 1.4e-38 yxiC S Family of unknown function (DUF5344)
ACFBBGHA_03081 1.5e-210 S nuclease activity
ACFBBGHA_03082 1e-45
ACFBBGHA_03083 6.9e-28 S Uncharacterized protein conserved in bacteria (DUF2247)
ACFBBGHA_03084 6.8e-21
ACFBBGHA_03085 1.3e-22 S Uncharacterized protein conserved in bacteria (DUF2247)
ACFBBGHA_03086 3.4e-306 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ACFBBGHA_03087 9.3e-280 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
ACFBBGHA_03088 1.2e-71 yxiE T Belongs to the universal stress protein A family
ACFBBGHA_03089 5.5e-34 S Sporulation delaying protein SdpA
ACFBBGHA_03090 8e-89
ACFBBGHA_03091 3.6e-12
ACFBBGHA_03092 3.6e-62 K helix_turn_helix, mercury resistance
ACFBBGHA_03093 1.3e-18
ACFBBGHA_03094 5.6e-164 yxxF EG EamA-like transporter family
ACFBBGHA_03095 0.0 wapA M COG3209 Rhs family protein
ACFBBGHA_03096 1.5e-71 yxxG
ACFBBGHA_03097 1.7e-84
ACFBBGHA_03098 6.4e-63
ACFBBGHA_03099 3.7e-75 yxiG
ACFBBGHA_03100 2e-139
ACFBBGHA_03101 4.6e-93 yxiI S Protein of unknown function (DUF2716)
ACFBBGHA_03102 8.6e-42 yxiJ S YxiJ-like protein
ACFBBGHA_03105 1.7e-210 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
ACFBBGHA_03106 6.2e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
ACFBBGHA_03107 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
ACFBBGHA_03108 2.4e-111
ACFBBGHA_03109 8.3e-151 licT K transcriptional antiterminator
ACFBBGHA_03110 1.1e-143 exoK GH16 M licheninase activity
ACFBBGHA_03111 6.6e-224 citH C Citrate transporter
ACFBBGHA_03112 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
ACFBBGHA_03113 3e-47 yxiS
ACFBBGHA_03114 4e-103 T Domain of unknown function (DUF4163)
ACFBBGHA_03115 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACFBBGHA_03116 1.6e-157 rlmA 2.1.1.187 Q Methyltransferase domain
ACFBBGHA_03117 1.3e-249 yxjC EG COG2610 H gluconate symporter and related permeases
ACFBBGHA_03118 6.9e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACFBBGHA_03119 1.2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
ACFBBGHA_03120 2.4e-136 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
ACFBBGHA_03121 8.2e-218 yxjG 2.1.1.14 E Methionine synthase
ACFBBGHA_03122 1.8e-220 yxjG 2.1.1.14 E Methionine synthase
ACFBBGHA_03123 9.3e-86 yxjI S LURP-one-related
ACFBBGHA_03126 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
ACFBBGHA_03127 7.1e-113 K helix_turn_helix, Lux Regulon
ACFBBGHA_03128 8.3e-192 yxjM T Signal transduction histidine kinase
ACFBBGHA_03129 1e-76 S Protein of unknown function (DUF1453)
ACFBBGHA_03130 2.1e-165 yxjO K LysR substrate binding domain
ACFBBGHA_03131 1.3e-93 yxkA S Phosphatidylethanolamine-binding protein
ACFBBGHA_03132 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
ACFBBGHA_03133 1.4e-73 yxkC S Domain of unknown function (DUF4352)
ACFBBGHA_03134 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACFBBGHA_03135 8.8e-273 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
ACFBBGHA_03136 2.7e-163 lrp QT PucR C-terminal helix-turn-helix domain
ACFBBGHA_03137 2.2e-204 msmK P Belongs to the ABC transporter superfamily
ACFBBGHA_03138 1.6e-154 yxkH G Polysaccharide deacetylase
ACFBBGHA_03140 4.7e-310 3.4.24.84 O Peptidase family M48
ACFBBGHA_03141 1.5e-229 cimH C COG3493 Na citrate symporter
ACFBBGHA_03142 1.2e-266 cydA 1.10.3.14 C oxidase, subunit
ACFBBGHA_03143 5e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
ACFBBGHA_03144 4.7e-311 cydD V ATP-binding
ACFBBGHA_03145 0.0 cydD V ATP-binding protein
ACFBBGHA_03146 5.9e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACFBBGHA_03147 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
ACFBBGHA_03148 3.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
ACFBBGHA_03149 3.9e-48 yxlC S Family of unknown function (DUF5345)
ACFBBGHA_03150 1.4e-30
ACFBBGHA_03151 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
ACFBBGHA_03152 7e-164 yxlF V ABC transporter, ATP-binding protein
ACFBBGHA_03153 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
ACFBBGHA_03154 5.3e-215 yxlH EGP Major facilitator Superfamily
ACFBBGHA_03155 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
ACFBBGHA_03156 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
ACFBBGHA_03157 1.1e-19 yxzF
ACFBBGHA_03158 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
ACFBBGHA_03159 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
ACFBBGHA_03160 2.8e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ACFBBGHA_03161 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
ACFBBGHA_03162 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
ACFBBGHA_03163 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
ACFBBGHA_03164 4.7e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_03165 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
ACFBBGHA_03166 5.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_03167 1.2e-232 dltB M membrane protein involved in D-alanine export
ACFBBGHA_03168 4.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_03169 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
ACFBBGHA_03170 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
ACFBBGHA_03171 4e-130 ynfM EGP Major facilitator Superfamily
ACFBBGHA_03172 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
ACFBBGHA_03173 1.4e-92 K Helix-turn-helix XRE-family like proteins
ACFBBGHA_03174 5.2e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
ACFBBGHA_03175 4.7e-227 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACFBBGHA_03176 2.3e-87 ywaE K Transcriptional regulator
ACFBBGHA_03177 4.3e-124 ywaF S Integral membrane protein
ACFBBGHA_03178 2.9e-167 gspA M General stress
ACFBBGHA_03179 1.2e-152 sacY K transcriptional antiterminator
ACFBBGHA_03180 2.2e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ACFBBGHA_03181 7.5e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
ACFBBGHA_03182 2.1e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
ACFBBGHA_03183 9.9e-67 ywbC 4.4.1.5 E glyoxalase
ACFBBGHA_03184 9.2e-220 ywbD 2.1.1.191 J Methyltransferase
ACFBBGHA_03185 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
ACFBBGHA_03186 9e-207 ywbF EGP Major facilitator Superfamily
ACFBBGHA_03187 2.3e-111 ywbG M effector of murein hydrolase
ACFBBGHA_03188 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
ACFBBGHA_03189 4.3e-153 ywbI K Transcriptional regulator
ACFBBGHA_03190 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ACFBBGHA_03191 9.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
ACFBBGHA_03192 9.3e-251 P COG0672 High-affinity Fe2 Pb2 permease
ACFBBGHA_03193 3.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
ACFBBGHA_03194 1.9e-223 ywbN P Dyp-type peroxidase family protein
ACFBBGHA_03195 6.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
ACFBBGHA_03196 9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACFBBGHA_03197 9.8e-49 ywcB S Protein of unknown function, DUF485
ACFBBGHA_03199 1.1e-121 ywcC K transcriptional regulator
ACFBBGHA_03200 9.5e-60 gtcA S GtrA-like protein
ACFBBGHA_03201 6.9e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ACFBBGHA_03202 4e-300 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
ACFBBGHA_03203 1e-35 ywzA S membrane
ACFBBGHA_03204 3.1e-176 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
ACFBBGHA_03205 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACFBBGHA_03206 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
ACFBBGHA_03207 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
ACFBBGHA_03208 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
ACFBBGHA_03209 2.9e-202 rodA D Belongs to the SEDS family
ACFBBGHA_03210 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
ACFBBGHA_03211 1.2e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACFBBGHA_03212 0.0 vpr O Belongs to the peptidase S8 family
ACFBBGHA_03214 7e-150 sacT K transcriptional antiterminator
ACFBBGHA_03215 2.6e-138 focA P Formate/nitrite transporter
ACFBBGHA_03216 4.7e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
ACFBBGHA_03217 3.2e-291 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
ACFBBGHA_03218 2e-28 ywdA
ACFBBGHA_03219 8.7e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
ACFBBGHA_03220 1.3e-57 pex K Transcriptional regulator PadR-like family
ACFBBGHA_03221 4e-113 ywdD
ACFBBGHA_03223 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
ACFBBGHA_03224 4.2e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ACFBBGHA_03225 6.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
ACFBBGHA_03226 2.9e-48 ywdI S Family of unknown function (DUF5327)
ACFBBGHA_03227 2.4e-237 ywdJ F Xanthine uracil
ACFBBGHA_03228 4.3e-59 ywdK S small membrane protein
ACFBBGHA_03229 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
ACFBBGHA_03230 2.6e-143 spsA M Spore Coat
ACFBBGHA_03231 2.6e-266 spsB M Capsule polysaccharide biosynthesis protein
ACFBBGHA_03232 6.7e-223 spsC E Belongs to the DegT DnrJ EryC1 family
ACFBBGHA_03233 2.9e-162 spsD 2.3.1.210 K Spore Coat
ACFBBGHA_03234 1.2e-213 spsE 2.5.1.56 M acid synthase
ACFBBGHA_03235 9.7e-132 spsF M Spore Coat
ACFBBGHA_03236 7.9e-188 spsG M Spore Coat
ACFBBGHA_03237 4.6e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ACFBBGHA_03238 1.5e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
ACFBBGHA_03239 1.7e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
ACFBBGHA_03240 1.3e-86 spsL 5.1.3.13 M Spore Coat
ACFBBGHA_03241 1.2e-77
ACFBBGHA_03242 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
ACFBBGHA_03243 8.6e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
ACFBBGHA_03244 0.0 rocB E arginine degradation protein
ACFBBGHA_03245 7.4e-250 lysP E amino acid
ACFBBGHA_03246 3.9e-205 ywfA EGP Major facilitator Superfamily
ACFBBGHA_03247 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
ACFBBGHA_03248 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
ACFBBGHA_03249 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_03250 8e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
ACFBBGHA_03251 1.2e-208 bacE EGP Major facilitator Superfamily
ACFBBGHA_03252 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
ACFBBGHA_03253 3.4e-138 IQ Enoyl-(Acyl carrier protein) reductase
ACFBBGHA_03254 3.3e-146 ywfI C May function as heme-dependent peroxidase
ACFBBGHA_03255 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
ACFBBGHA_03256 1.1e-156 cysL K Transcriptional regulator
ACFBBGHA_03257 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
ACFBBGHA_03258 2.2e-157 ywfM EG EamA-like transporter family
ACFBBGHA_03259 1.6e-111 rsfA_1
ACFBBGHA_03260 3.1e-36 ywzC S Belongs to the UPF0741 family
ACFBBGHA_03261 5.1e-256 ywfO S COG1078 HD superfamily phosphohydrolases
ACFBBGHA_03262 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
ACFBBGHA_03263 2.4e-78 yffB K Transcriptional regulator
ACFBBGHA_03264 2.1e-239 mmr U Major Facilitator Superfamily
ACFBBGHA_03266 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACFBBGHA_03267 9.5e-71 ywhA K Transcriptional regulator
ACFBBGHA_03268 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
ACFBBGHA_03269 5.1e-119 ywhC S Peptidase family M50
ACFBBGHA_03270 2e-94 ywhD S YwhD family
ACFBBGHA_03271 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
ACFBBGHA_03272 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACFBBGHA_03273 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
ACFBBGHA_03275 4.4e-59 V ATPases associated with a variety of cellular activities
ACFBBGHA_03278 1.3e-20
ACFBBGHA_03279 8.1e-10
ACFBBGHA_03281 2.6e-78 S aspartate phosphatase
ACFBBGHA_03282 2.7e-191 ywhK CO amine dehydrogenase activity
ACFBBGHA_03283 9.5e-245 ywhL CO amine dehydrogenase activity
ACFBBGHA_03285 2.2e-243 L Peptidase, M16
ACFBBGHA_03286 8.5e-218 2.7.1.26, 2.7.7.2 L Peptidase, M16
ACFBBGHA_03287 2.7e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
ACFBBGHA_03288 3.3e-132 cbiO V ABC transporter
ACFBBGHA_03290 4.9e-270 C Fe-S oxidoreductases
ACFBBGHA_03291 1e-07 S Bacteriocin subtilosin A
ACFBBGHA_03292 4.7e-73 ywiB S protein conserved in bacteria
ACFBBGHA_03293 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
ACFBBGHA_03294 2.3e-213 narK P COG2223 Nitrate nitrite transporter
ACFBBGHA_03295 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
ACFBBGHA_03296 1.7e-139 ywiC S YwiC-like protein
ACFBBGHA_03297 4.5e-85 arfM T cyclic nucleotide binding
ACFBBGHA_03298 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ACFBBGHA_03299 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
ACFBBGHA_03300 5.2e-93 narJ 1.7.5.1 C nitrate reductase
ACFBBGHA_03301 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
ACFBBGHA_03302 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACFBBGHA_03303 0.0 ywjA V ABC transporter
ACFBBGHA_03304 2.6e-94 ywjB H RibD C-terminal domain
ACFBBGHA_03305 2.7e-42 ywjC
ACFBBGHA_03306 1.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
ACFBBGHA_03307 1.3e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
ACFBBGHA_03308 0.0 fadF C COG0247 Fe-S oxidoreductase
ACFBBGHA_03309 8.2e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
ACFBBGHA_03310 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
ACFBBGHA_03311 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
ACFBBGHA_03312 1.3e-90 ywjG S Domain of unknown function (DUF2529)
ACFBBGHA_03313 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
ACFBBGHA_03314 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
ACFBBGHA_03315 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACFBBGHA_03316 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACFBBGHA_03317 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
ACFBBGHA_03318 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACFBBGHA_03319 1.1e-32 rpmE J Binds the 23S rRNA
ACFBBGHA_03320 5.4e-104 tdk 2.7.1.21 F thymidine kinase
ACFBBGHA_03321 0.0 sfcA 1.1.1.38 C malic enzyme
ACFBBGHA_03322 8.6e-160 ywkB S Membrane transport protein
ACFBBGHA_03323 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
ACFBBGHA_03324 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ACFBBGHA_03325 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACFBBGHA_03326 1.2e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
ACFBBGHA_03328 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
ACFBBGHA_03329 6.1e-112 spoIIR S stage II sporulation protein R
ACFBBGHA_03330 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
ACFBBGHA_03331 8.1e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
ACFBBGHA_03332 1.7e-91 mntP P Probably functions as a manganese efflux pump
ACFBBGHA_03333 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACFBBGHA_03334 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
ACFBBGHA_03335 3.6e-94 ywlG S Belongs to the UPF0340 family
ACFBBGHA_03336 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACFBBGHA_03337 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACFBBGHA_03338 2.5e-62 atpI S ATP synthase
ACFBBGHA_03339 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
ACFBBGHA_03340 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACFBBGHA_03341 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ACFBBGHA_03342 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACFBBGHA_03343 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACFBBGHA_03344 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACFBBGHA_03345 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACFBBGHA_03346 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
ACFBBGHA_03347 1.8e-86 ywmA
ACFBBGHA_03348 1.3e-32 ywzB S membrane
ACFBBGHA_03349 1.3e-131 ywmB S TATA-box binding
ACFBBGHA_03350 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACFBBGHA_03351 1.7e-174 spoIID D Stage II sporulation protein D
ACFBBGHA_03352 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
ACFBBGHA_03353 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
ACFBBGHA_03355 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACFBBGHA_03356 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACFBBGHA_03357 1.3e-103 S response regulator aspartate phosphatase
ACFBBGHA_03358 3e-84 ywmF S Peptidase M50
ACFBBGHA_03359 3.8e-11 csbD K CsbD-like
ACFBBGHA_03360 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
ACFBBGHA_03361 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
ACFBBGHA_03362 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
ACFBBGHA_03363 1.7e-64 ywnA K Transcriptional regulator
ACFBBGHA_03364 5.8e-112 ywnB S NAD(P)H-binding
ACFBBGHA_03365 2.6e-59 ywnC S Family of unknown function (DUF5362)
ACFBBGHA_03366 4.5e-143 mta K transcriptional
ACFBBGHA_03367 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACFBBGHA_03368 2.2e-70 ywnF S Family of unknown function (DUF5392)
ACFBBGHA_03369 7.5e-09 ywnC S Family of unknown function (DUF5362)
ACFBBGHA_03370 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
ACFBBGHA_03371 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
ACFBBGHA_03372 1.7e-72 ywnJ S VanZ like family
ACFBBGHA_03373 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
ACFBBGHA_03374 1.6e-58 nrgB K Belongs to the P(II) protein family
ACFBBGHA_03375 4.3e-225 amt P Ammonium transporter
ACFBBGHA_03376 7.5e-77
ACFBBGHA_03377 4e-104 phzA Q Isochorismatase family
ACFBBGHA_03378 5.4e-240 ywoD EGP Major facilitator superfamily
ACFBBGHA_03379 6.3e-279 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
ACFBBGHA_03380 1.4e-230 ywoF P Right handed beta helix region
ACFBBGHA_03381 2.7e-211 ywoG EGP Major facilitator Superfamily
ACFBBGHA_03382 2.1e-70 ywoH K COG1846 Transcriptional regulators
ACFBBGHA_03383 3e-44 spoIIID K Stage III sporulation protein D
ACFBBGHA_03384 3.5e-180 mbl D Rod shape-determining protein
ACFBBGHA_03385 3.4e-125 flhO N flagellar basal body
ACFBBGHA_03386 1.9e-139 flhP N flagellar basal body
ACFBBGHA_03387 7.5e-197 S aspartate phosphatase
ACFBBGHA_03388 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
ACFBBGHA_03389 8.7e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
ACFBBGHA_03390 7.8e-144 ywpD T Histidine kinase
ACFBBGHA_03391 2e-49 srtA 3.4.22.70 M Sortase family
ACFBBGHA_03392 6.9e-66 ywpF S YwpF-like protein
ACFBBGHA_03393 1.9e-65 ywpG
ACFBBGHA_03394 9.8e-58 ssbB L Single-stranded DNA-binding protein
ACFBBGHA_03395 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
ACFBBGHA_03396 5.7e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
ACFBBGHA_03397 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
ACFBBGHA_03398 3.5e-307 ywqB S SWIM zinc finger
ACFBBGHA_03399 1.2e-17
ACFBBGHA_03400 2e-116 ywqC M biosynthesis protein
ACFBBGHA_03401 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
ACFBBGHA_03402 2.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
ACFBBGHA_03403 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACFBBGHA_03404 2.1e-151 ywqG S Domain of unknown function (DUF1963)
ACFBBGHA_03405 9.7e-23 S Domain of unknown function (DUF5082)
ACFBBGHA_03406 3.9e-38 ywqI S Family of unknown function (DUF5344)
ACFBBGHA_03407 2.7e-242 ywqJ S Pre-toxin TG
ACFBBGHA_03408 3.9e-25
ACFBBGHA_03409 6.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
ACFBBGHA_03410 4.2e-161 K Transcriptional regulator
ACFBBGHA_03411 3.3e-100 ywqN S NAD(P)H-dependent
ACFBBGHA_03413 6.4e-88 ywrA P COG2059 Chromate transport protein ChrA
ACFBBGHA_03414 1e-102 ywrB P Chromate transporter
ACFBBGHA_03415 8e-82 ywrC K Transcriptional regulator
ACFBBGHA_03416 2.1e-304 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
ACFBBGHA_03417 5e-54 S Domain of unknown function (DUF4181)
ACFBBGHA_03418 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACFBBGHA_03419 3.7e-12
ACFBBGHA_03420 1.2e-210 cotH M Spore Coat
ACFBBGHA_03421 7.6e-131 cotB
ACFBBGHA_03422 1.1e-124 ywrJ
ACFBBGHA_03423 5.5e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACFBBGHA_03424 1.1e-169 alsR K LysR substrate binding domain
ACFBBGHA_03425 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
ACFBBGHA_03426 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
ACFBBGHA_03427 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
ACFBBGHA_03428 8e-48 ywsA S Protein of unknown function (DUF3892)
ACFBBGHA_03429 8.7e-93 batE T Sh3 type 3 domain protein
ACFBBGHA_03430 7.1e-136 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
ACFBBGHA_03431 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
ACFBBGHA_03432 1.1e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
ACFBBGHA_03433 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
ACFBBGHA_03434 2.7e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACFBBGHA_03435 9.3e-178 rbsR K transcriptional
ACFBBGHA_03436 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
ACFBBGHA_03437 8.6e-70 pgsC S biosynthesis protein
ACFBBGHA_03438 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
ACFBBGHA_03439 3.6e-21 ywtC
ACFBBGHA_03440 1e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
ACFBBGHA_03441 2.9e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
ACFBBGHA_03442 1.7e-168 ywtF K Transcriptional regulator
ACFBBGHA_03443 4.1e-248 ywtG EGP Major facilitator Superfamily
ACFBBGHA_03444 7.6e-216 gerAC S Spore germination protein
ACFBBGHA_03445 7.5e-200 gerBB E Spore germination protein
ACFBBGHA_03446 3.5e-266 gerBA EG Spore germination protein
ACFBBGHA_03447 1.1e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
ACFBBGHA_03448 2e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ACFBBGHA_03449 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ACFBBGHA_03450 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ACFBBGHA_03451 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
ACFBBGHA_03452 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
ACFBBGHA_03453 4.6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ACFBBGHA_03454 9.2e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
ACFBBGHA_03455 2.1e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
ACFBBGHA_03456 5.3e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ACFBBGHA_03457 1.3e-111 ggaA M Glycosyltransferase like family 2
ACFBBGHA_03458 1.1e-87
ACFBBGHA_03459 2.7e-131 M Glycosyltransferase like family 2
ACFBBGHA_03460 3.3e-148 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
ACFBBGHA_03461 8.5e-132 tagG GM Transport permease protein
ACFBBGHA_03462 2.1e-267 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
ACFBBGHA_03463 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
ACFBBGHA_03464 6.3e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
ACFBBGHA_03465 5.4e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
ACFBBGHA_03466 2.1e-88 M Glycosyltransferase like family 2
ACFBBGHA_03467 4.7e-213 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
ACFBBGHA_03468 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
ACFBBGHA_03469 7.7e-12
ACFBBGHA_03470 0.0 lytB 3.5.1.28 D Stage II sporulation protein
ACFBBGHA_03471 2.4e-209 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ACFBBGHA_03472 1.5e-94 M Glycosyltransferase like family 2
ACFBBGHA_03473 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
ACFBBGHA_03474 1.7e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ACFBBGHA_03475 4.2e-217 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
ACFBBGHA_03476 2.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACFBBGHA_03477 2.4e-262 tuaE M Teichuronic acid biosynthesis protein
ACFBBGHA_03478 9.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
ACFBBGHA_03479 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
ACFBBGHA_03480 1.1e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
ACFBBGHA_03481 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
ACFBBGHA_03482 6e-163 yvhJ K Transcriptional regulator
ACFBBGHA_03483 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
ACFBBGHA_03484 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
ACFBBGHA_03485 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ACFBBGHA_03486 7.3e-155 degV S protein conserved in bacteria
ACFBBGHA_03487 4.4e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ACFBBGHA_03488 1.1e-44 comFB S Late competence development protein ComFB
ACFBBGHA_03489 1.2e-126 comFC S Phosphoribosyl transferase domain
ACFBBGHA_03490 7e-74 yvyF S flagellar protein
ACFBBGHA_03491 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
ACFBBGHA_03492 1.6e-77 flgN NOU FlgN protein
ACFBBGHA_03493 1.2e-264 flgK N flagellar hook-associated protein
ACFBBGHA_03494 7.8e-155 flgL N Belongs to the bacterial flagellin family
ACFBBGHA_03495 5.7e-50 yviE
ACFBBGHA_03496 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ACFBBGHA_03497 5.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACFBBGHA_03498 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACFBBGHA_03499 1.8e-56 flaG N flagellar protein FlaG
ACFBBGHA_03500 2.8e-250 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACFBBGHA_03501 4.2e-68 fliS N flagellar protein FliS
ACFBBGHA_03502 1.9e-08 fliT S bacterial-type flagellum organization
ACFBBGHA_03503 2.8e-66
ACFBBGHA_03504 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACFBBGHA_03505 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
ACFBBGHA_03506 2.3e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACFBBGHA_03507 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
ACFBBGHA_03508 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
ACFBBGHA_03509 1.6e-123 ftsE D cell division ATP-binding protein FtsE
ACFBBGHA_03510 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
ACFBBGHA_03511 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
ACFBBGHA_03512 5.3e-56 swrA S Swarming motility protein
ACFBBGHA_03513 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACFBBGHA_03514 8.1e-225 yvkA EGP Major facilitator Superfamily
ACFBBGHA_03515 7e-101 yvkB K Transcriptional regulator
ACFBBGHA_03516 0.0 yvkC 2.7.9.2 GT Phosphotransferase
ACFBBGHA_03517 1.2e-30 csbA S protein conserved in bacteria
ACFBBGHA_03518 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
ACFBBGHA_03519 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
ACFBBGHA_03520 3.6e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACFBBGHA_03521 5.7e-33 yvkN
ACFBBGHA_03522 8e-49 yvlA
ACFBBGHA_03523 3.4e-168 yvlB S Putative adhesin
ACFBBGHA_03524 2.6e-26 pspB KT PspC domain
ACFBBGHA_03525 1.2e-50 yvlD S Membrane
ACFBBGHA_03526 3e-202 yvmA EGP Major facilitator Superfamily
ACFBBGHA_03527 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
ACFBBGHA_03528 2.3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
ACFBBGHA_03529 2.5e-228 cypX 1.14.15.13 C Cytochrome P450
ACFBBGHA_03530 4.2e-72 adcR K helix_turn_helix multiple antibiotic resistance protein
ACFBBGHA_03531 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
ACFBBGHA_03532 1.8e-133 yvoA K transcriptional
ACFBBGHA_03533 1.2e-126 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
ACFBBGHA_03534 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
ACFBBGHA_03535 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ACFBBGHA_03536 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ACFBBGHA_03537 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
ACFBBGHA_03538 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
ACFBBGHA_03539 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
ACFBBGHA_03540 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
ACFBBGHA_03541 3.8e-139 yvpB NU protein conserved in bacteria
ACFBBGHA_03542 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACFBBGHA_03543 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
ACFBBGHA_03544 4.1e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACFBBGHA_03545 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
ACFBBGHA_03546 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACFBBGHA_03547 9.9e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACFBBGHA_03548 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
ACFBBGHA_03549 4.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
ACFBBGHA_03550 5.8e-65
ACFBBGHA_03551 4.9e-75
ACFBBGHA_03552 0.0
ACFBBGHA_03554 0.0 msbA2 3.6.3.44 V ABC transporter
ACFBBGHA_03555 1.2e-277 S COG0457 FOG TPR repeat
ACFBBGHA_03556 1.1e-97 usp CBM50 M protein conserved in bacteria
ACFBBGHA_03557 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
ACFBBGHA_03558 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
ACFBBGHA_03559 5.7e-166 rapZ S Displays ATPase and GTPase activities
ACFBBGHA_03560 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
ACFBBGHA_03561 1.4e-170 whiA K May be required for sporulation
ACFBBGHA_03562 1.6e-36 crh G Phosphocarrier protein Chr
ACFBBGHA_03563 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
ACFBBGHA_03564 1.8e-33
ACFBBGHA_03565 4.3e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_03566 9.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
ACFBBGHA_03567 2.1e-140 yvcR V ABC transporter, ATP-binding protein
ACFBBGHA_03568 0.0 yxdM V ABC transporter (permease)
ACFBBGHA_03569 8.7e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACFBBGHA_03570 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
ACFBBGHA_03571 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
ACFBBGHA_03572 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
ACFBBGHA_03573 6.8e-104 yvdD 3.2.2.10 S Belongs to the LOG family
ACFBBGHA_03574 8.8e-173 yvdE K Transcriptional regulator
ACFBBGHA_03575 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
ACFBBGHA_03576 2e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
ACFBBGHA_03577 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
ACFBBGHA_03578 3.9e-148 malD P transport
ACFBBGHA_03579 5.5e-153 malA S Protein of unknown function (DUF1189)
ACFBBGHA_03580 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
ACFBBGHA_03581 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
ACFBBGHA_03582 3.9e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
ACFBBGHA_03583 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
ACFBBGHA_03585 1.2e-182 S Patatin-like phospholipase
ACFBBGHA_03586 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
ACFBBGHA_03587 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
ACFBBGHA_03588 4.1e-50 sugE P Small Multidrug Resistance protein
ACFBBGHA_03589 1.5e-50 ykkC P Small Multidrug Resistance protein
ACFBBGHA_03590 7.4e-106 yvdT K Transcriptional regulator
ACFBBGHA_03591 1.8e-295 yveA E amino acid
ACFBBGHA_03592 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
ACFBBGHA_03593 4.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
ACFBBGHA_03594 2.1e-260 pbpE V Beta-lactamase
ACFBBGHA_03595 1.9e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
ACFBBGHA_03596 1.7e-73 MA20_18690 S Protein of unknown function (DUF3237)
ACFBBGHA_03597 1.7e-92 padC Q Phenolic acid decarboxylase
ACFBBGHA_03599 2.5e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
ACFBBGHA_03600 6.3e-76 slr K transcriptional
ACFBBGHA_03601 4e-122 ywqC M biosynthesis protein
ACFBBGHA_03602 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
ACFBBGHA_03603 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
ACFBBGHA_03604 2.5e-222 epsD GT4 M Glycosyl transferase 4-like
ACFBBGHA_03605 4.5e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
ACFBBGHA_03606 2.5e-214 epsF GT4 M Glycosyl transferases group 1
ACFBBGHA_03607 2.4e-206 epsG S EpsG family
ACFBBGHA_03608 4.4e-194 epsH GT2 S Glycosyltransferase like family 2
ACFBBGHA_03609 2.4e-203 epsI GM pyruvyl transferase
ACFBBGHA_03610 3.1e-195 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
ACFBBGHA_03611 1.1e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ACFBBGHA_03612 5.7e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
ACFBBGHA_03613 6.9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
ACFBBGHA_03614 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
ACFBBGHA_03615 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
ACFBBGHA_03616 1e-31 yvfG S YvfG protein
ACFBBGHA_03617 5.2e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
ACFBBGHA_03618 2.2e-307 yvfH C L-lactate permease
ACFBBGHA_03619 3.5e-113 yvfI K COG2186 Transcriptional regulators
ACFBBGHA_03620 5.2e-184 lacR K Transcriptional regulator
ACFBBGHA_03621 6.1e-230 cycB G COG2182 Maltose-binding periplasmic proteins domains
ACFBBGHA_03622 9.3e-231 malC P COG1175 ABC-type sugar transport systems, permease components
ACFBBGHA_03623 7.2e-150 ganQ P transport
ACFBBGHA_03624 0.0 lacA 3.2.1.23 G beta-galactosidase
ACFBBGHA_03625 3.5e-249 galA 3.2.1.89 G arabinogalactan
ACFBBGHA_03626 1.4e-194 rsbU 3.1.3.3 T response regulator
ACFBBGHA_03627 2.2e-156 rsbQ S Alpha/beta hydrolase family
ACFBBGHA_03628 1.8e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
ACFBBGHA_03629 7.6e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
ACFBBGHA_03630 4.3e-195 desK 2.7.13.3 T Histidine kinase
ACFBBGHA_03631 3.8e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ACFBBGHA_03632 2.2e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
ACFBBGHA_03633 2.3e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
ACFBBGHA_03634 1.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
ACFBBGHA_03635 1.2e-196 yvbX S Glycosyl hydrolase
ACFBBGHA_03636 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
ACFBBGHA_03637 7.2e-156 yvbV EG EamA-like transporter family
ACFBBGHA_03638 5.1e-159 yvbU K Transcriptional regulator
ACFBBGHA_03639 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACFBBGHA_03640 5.5e-203 araR K transcriptional
ACFBBGHA_03641 6.2e-252 araE EGP Major facilitator Superfamily
ACFBBGHA_03642 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
ACFBBGHA_03643 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
ACFBBGHA_03644 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
ACFBBGHA_03645 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
ACFBBGHA_03646 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
ACFBBGHA_03647 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
ACFBBGHA_03648 1.3e-81 yvbK 3.1.3.25 K acetyltransferase
ACFBBGHA_03649 0.0 tcaA S response to antibiotic
ACFBBGHA_03650 3e-122 exoY M Membrane
ACFBBGHA_03651 6.2e-111 yvbH S YvbH-like oligomerisation region
ACFBBGHA_03652 2.4e-102 yvbG U UPF0056 membrane protein
ACFBBGHA_03653 3.5e-97 yvbF K Belongs to the GbsR family
ACFBBGHA_03654 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
ACFBBGHA_03655 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
ACFBBGHA_03656 7.9e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ACFBBGHA_03657 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
ACFBBGHA_03658 3.3e-60 yvbF K Belongs to the GbsR family
ACFBBGHA_03659 1.2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
ACFBBGHA_03660 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
ACFBBGHA_03661 2.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
ACFBBGHA_03662 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
ACFBBGHA_03663 1.8e-224 NT chemotaxis protein
ACFBBGHA_03664 2.2e-54 yodB K transcriptional
ACFBBGHA_03665 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
ACFBBGHA_03666 4e-69 K transcriptional
ACFBBGHA_03667 7.5e-36 yvzC K Transcriptional
ACFBBGHA_03668 3.4e-151 yvaM S Serine aminopeptidase, S33
ACFBBGHA_03669 2.4e-23 secG U Preprotein translocase subunit SecG
ACFBBGHA_03670 5.6e-143 est 3.1.1.1 S Carboxylesterase
ACFBBGHA_03671 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
ACFBBGHA_03672 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACFBBGHA_03674 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_03675 6.7e-96 K Bacterial regulatory proteins, tetR family
ACFBBGHA_03676 2.4e-54 yvaE P Small Multidrug Resistance protein
ACFBBGHA_03677 1.3e-72 yvaD S Family of unknown function (DUF5360)
ACFBBGHA_03678 0.0 yvaC S Fusaric acid resistance protein-like
ACFBBGHA_03679 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACFBBGHA_03680 1.2e-194 yvaA 1.1.1.371 S Oxidoreductase
ACFBBGHA_03681 8.2e-48 csoR S transcriptional
ACFBBGHA_03682 5.9e-29 copZ P Copper resistance protein CopZ
ACFBBGHA_03683 0.0 copA 3.6.3.54 P P-type ATPase
ACFBBGHA_03684 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
ACFBBGHA_03685 1.8e-103 bdbD O Thioredoxin
ACFBBGHA_03686 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
ACFBBGHA_03687 1.6e-106 yvgT S membrane
ACFBBGHA_03689 0.0 helD 3.6.4.12 L DNA helicase
ACFBBGHA_03690 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACFBBGHA_03691 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
ACFBBGHA_03692 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
ACFBBGHA_03693 1.2e-85 yvgO
ACFBBGHA_03694 5.9e-157 yvgN S reductase
ACFBBGHA_03695 1.3e-117 modB P COG4149 ABC-type molybdate transport system, permease component
ACFBBGHA_03696 1.2e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
ACFBBGHA_03697 2.9e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
ACFBBGHA_03698 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
ACFBBGHA_03699 2.5e-83 yvsG S LexA-binding, inner membrane-associated putative hydrolase
ACFBBGHA_03700 6.5e-16 S Small spore protein J (Spore_SspJ)
ACFBBGHA_03701 4.9e-236 yvsH E Arginine ornithine antiporter
ACFBBGHA_03702 1.2e-177 fhuD P ABC transporter
ACFBBGHA_03703 3.5e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_03704 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_03705 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
ACFBBGHA_03706 2e-174 M Efflux transporter rnd family, mfp subunit
ACFBBGHA_03707 1.6e-123 macB V ABC transporter, ATP-binding protein
ACFBBGHA_03708 1.2e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
ACFBBGHA_03709 1.3e-64 yvrL S Regulatory protein YrvL
ACFBBGHA_03710 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
ACFBBGHA_03711 2.4e-19 S YvrJ protein family
ACFBBGHA_03712 2.1e-97 yvrI K RNA polymerase
ACFBBGHA_03713 7.2e-23
ACFBBGHA_03714 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_03715 0.0 T PhoQ Sensor
ACFBBGHA_03716 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
ACFBBGHA_03717 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_03718 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
ACFBBGHA_03719 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACFBBGHA_03720 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
ACFBBGHA_03721 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
ACFBBGHA_03722 4.8e-227 yvqJ EGP Major facilitator Superfamily
ACFBBGHA_03723 5.6e-62 liaI S membrane
ACFBBGHA_03724 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
ACFBBGHA_03725 9.3e-129 liaG S Putative adhesin
ACFBBGHA_03726 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
ACFBBGHA_03727 5.5e-187 vraS 2.7.13.3 T Histidine kinase
ACFBBGHA_03728 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ACFBBGHA_03729 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
ACFBBGHA_03730 9.1e-198 gerAB E Spore germination protein
ACFBBGHA_03731 3.7e-247 gerAA EG Spore germination protein
ACFBBGHA_03732 2.3e-24 S Protein of unknown function (DUF3970)
ACFBBGHA_03733 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
ACFBBGHA_03734 3.1e-156 yuxN K Transcriptional regulator
ACFBBGHA_03735 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
ACFBBGHA_03736 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
ACFBBGHA_03737 7.8e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACFBBGHA_03738 1.2e-79 dps P Ferritin-like domain
ACFBBGHA_03739 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_03740 6.5e-302 pepF2 E COG1164 Oligoendopeptidase F
ACFBBGHA_03741 1.9e-66 S YusW-like protein
ACFBBGHA_03742 1e-153 yusV 3.6.3.34 HP ABC transporter
ACFBBGHA_03743 3.8e-47 yusU S Protein of unknown function (DUF2573)
ACFBBGHA_03744 2.2e-157 yusT K LysR substrate binding domain
ACFBBGHA_03745 1.7e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_03746 1.8e-63 yusQ S Tautomerase enzyme
ACFBBGHA_03747 1.1e-292 yusP P Major facilitator superfamily
ACFBBGHA_03748 8.7e-73 yusO K Iron dependent repressor, N-terminal DNA binding domain
ACFBBGHA_03749 7.1e-53 yusN M Coat F domain
ACFBBGHA_03750 5.1e-40
ACFBBGHA_03751 3.2e-164 fadM E Proline dehydrogenase
ACFBBGHA_03752 8.1e-09 S YuzL-like protein
ACFBBGHA_03753 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
ACFBBGHA_03754 3.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
ACFBBGHA_03755 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
ACFBBGHA_03756 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
ACFBBGHA_03757 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
ACFBBGHA_03758 1.1e-39 yusG S Protein of unknown function (DUF2553)
ACFBBGHA_03759 4.8e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
ACFBBGHA_03760 5.6e-55 traF CO Thioredoxin
ACFBBGHA_03761 3.2e-56 yusD S SCP-2 sterol transfer family
ACFBBGHA_03762 1.8e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACFBBGHA_03763 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
ACFBBGHA_03764 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
ACFBBGHA_03765 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACFBBGHA_03766 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
ACFBBGHA_03767 1.4e-245 sufD O assembly protein SufD
ACFBBGHA_03768 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACFBBGHA_03769 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
ACFBBGHA_03770 3.5e-271 sufB O FeS cluster assembly
ACFBBGHA_03771 1.1e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
ACFBBGHA_03772 1.3e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
ACFBBGHA_03773 1.8e-41
ACFBBGHA_03775 1.3e-202 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
ACFBBGHA_03776 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
ACFBBGHA_03777 8.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
ACFBBGHA_03778 1e-237 yurO G COG1653 ABC-type sugar transport system, periplasmic component
ACFBBGHA_03779 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
ACFBBGHA_03780 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
ACFBBGHA_03781 1.1e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
ACFBBGHA_03782 1.1e-135 yurK K UTRA
ACFBBGHA_03783 5.9e-205 msmX P Belongs to the ABC transporter superfamily
ACFBBGHA_03784 2.9e-167 bsn L Ribonuclease
ACFBBGHA_03785 1.1e-231 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
ACFBBGHA_03786 3e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
ACFBBGHA_03787 3.8e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ACFBBGHA_03788 7.6e-109 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
ACFBBGHA_03789 4.9e-143 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
ACFBBGHA_03790 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
ACFBBGHA_03791 2e-94 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
ACFBBGHA_03792 6.6e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
ACFBBGHA_03793 2.6e-280 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
ACFBBGHA_03794 4.8e-222 pbuX F xanthine
ACFBBGHA_03795 8.8e-235 pbuX F Permease family
ACFBBGHA_03796 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
ACFBBGHA_03797 1.9e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
ACFBBGHA_03798 2.8e-60 yunG
ACFBBGHA_03799 4.3e-171 yunF S Protein of unknown function DUF72
ACFBBGHA_03800 2e-141 yunE S membrane transporter protein
ACFBBGHA_03801 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
ACFBBGHA_03802 3.1e-47 yunC S Domain of unknown function (DUF1805)
ACFBBGHA_03803 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
ACFBBGHA_03804 3.8e-195 lytH M Peptidase, M23
ACFBBGHA_03805 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACFBBGHA_03806 2.4e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
ACFBBGHA_03807 9.7e-48 yutD S protein conserved in bacteria
ACFBBGHA_03808 1e-75 yutE S Protein of unknown function DUF86
ACFBBGHA_03809 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
ACFBBGHA_03810 3.3e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
ACFBBGHA_03811 2.9e-198 yutH S Spore coat protein
ACFBBGHA_03812 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
ACFBBGHA_03813 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACFBBGHA_03814 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
ACFBBGHA_03815 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
ACFBBGHA_03816 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
ACFBBGHA_03817 3.3e-55 yuzD S protein conserved in bacteria
ACFBBGHA_03818 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
ACFBBGHA_03819 3.2e-39 yuzB S Belongs to the UPF0349 family
ACFBBGHA_03820 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACFBBGHA_03821 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ACFBBGHA_03822 3.7e-63 erpA S Belongs to the HesB IscA family
ACFBBGHA_03824 1e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
ACFBBGHA_03825 7.6e-117 paiB K Putative FMN-binding domain
ACFBBGHA_03826 1.9e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
ACFBBGHA_03828 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
ACFBBGHA_03829 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
ACFBBGHA_03830 8.4e-27 yuiB S Putative membrane protein
ACFBBGHA_03831 8e-117 yuiC S protein conserved in bacteria
ACFBBGHA_03832 1.2e-77 yuiD S protein conserved in bacteria
ACFBBGHA_03833 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACFBBGHA_03834 3.9e-211 yuiF S antiporter
ACFBBGHA_03835 4.4e-93 bioY S Biotin biosynthesis protein
ACFBBGHA_03836 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
ACFBBGHA_03837 7.4e-166 besA S Putative esterase
ACFBBGHA_03838 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
ACFBBGHA_03839 2.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
ACFBBGHA_03840 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
ACFBBGHA_03841 3.1e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
ACFBBGHA_03842 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_03843 5e-36 mbtH S MbtH-like protein
ACFBBGHA_03844 9.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
ACFBBGHA_03845 1.4e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
ACFBBGHA_03846 1.5e-228 yukF QT Transcriptional regulator
ACFBBGHA_03847 2.8e-45 esxA S Belongs to the WXG100 family
ACFBBGHA_03848 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
ACFBBGHA_03849 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
ACFBBGHA_03850 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
ACFBBGHA_03851 0.0 esaA S type VII secretion protein EsaA
ACFBBGHA_03852 3.3e-64 yueC S Family of unknown function (DUF5383)
ACFBBGHA_03853 1.7e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ACFBBGHA_03854 4.8e-96 yueE S phosphohydrolase
ACFBBGHA_03855 2.9e-24 S Protein of unknown function (DUF2642)
ACFBBGHA_03856 3.8e-66 S Protein of unknown function (DUF2283)
ACFBBGHA_03857 6e-189 yueF S transporter activity
ACFBBGHA_03858 2.1e-32 yueG S Spore germination protein gerPA/gerPF
ACFBBGHA_03859 2.8e-38 yueH S YueH-like protein
ACFBBGHA_03860 7.9e-67 yueI S Protein of unknown function (DUF1694)
ACFBBGHA_03861 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
ACFBBGHA_03862 1e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACFBBGHA_03863 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
ACFBBGHA_03864 1.1e-22 yuzC
ACFBBGHA_03866 3e-141 comQ H Belongs to the FPP GGPP synthase family
ACFBBGHA_03868 2.4e-269 comP 2.7.13.3 T Histidine kinase
ACFBBGHA_03869 2.5e-115 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
ACFBBGHA_03870 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
ACFBBGHA_03871 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
ACFBBGHA_03872 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ACFBBGHA_03873 2.4e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ACFBBGHA_03874 1.9e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ACFBBGHA_03875 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ACFBBGHA_03876 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
ACFBBGHA_03877 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
ACFBBGHA_03878 3.2e-14
ACFBBGHA_03879 1.3e-233 maeN C COG3493 Na citrate symporter
ACFBBGHA_03880 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
ACFBBGHA_03881 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
ACFBBGHA_03882 7.8e-272 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
ACFBBGHA_03883 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
ACFBBGHA_03884 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
ACFBBGHA_03885 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
ACFBBGHA_03886 6.3e-78 yufK S Family of unknown function (DUF5366)
ACFBBGHA_03887 6.3e-75 yuxK S protein conserved in bacteria
ACFBBGHA_03888 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
ACFBBGHA_03889 2.1e-183 yuxJ EGP Major facilitator Superfamily
ACFBBGHA_03891 1.9e-115 kapD L the KinA pathway to sporulation
ACFBBGHA_03892 1.8e-68 kapB G Kinase associated protein B
ACFBBGHA_03893 4.6e-233 T PhoQ Sensor
ACFBBGHA_03894 1.3e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
ACFBBGHA_03895 7.8e-39 yugE S Domain of unknown function (DUF1871)
ACFBBGHA_03896 1.1e-155 yugF I Hydrolase
ACFBBGHA_03897 1.6e-85 alaR K Transcriptional regulator
ACFBBGHA_03898 2.1e-199 yugH 2.6.1.1 E Aminotransferase
ACFBBGHA_03899 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
ACFBBGHA_03900 1.1e-34 yuzA S Domain of unknown function (DUF378)
ACFBBGHA_03901 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
ACFBBGHA_03902 1.1e-228 yugK C Dehydrogenase
ACFBBGHA_03903 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
ACFBBGHA_03905 2.8e-72 yugN S YugN-like family
ACFBBGHA_03906 8.2e-182 yugO P COG1226 Kef-type K transport systems
ACFBBGHA_03907 5.4e-53 mstX S Membrane-integrating protein Mistic
ACFBBGHA_03908 3.9e-38
ACFBBGHA_03909 1.4e-116 yugP S Zn-dependent protease
ACFBBGHA_03910 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
ACFBBGHA_03911 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
ACFBBGHA_03912 2.1e-72 yugU S Uncharacterised protein family UPF0047
ACFBBGHA_03913 2.3e-35
ACFBBGHA_03914 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
ACFBBGHA_03915 3.2e-225 mcpA NT chemotaxis protein
ACFBBGHA_03916 1.2e-219 mcpA NT chemotaxis protein
ACFBBGHA_03917 1.4e-294 mcpA NT chemotaxis protein
ACFBBGHA_03918 7.3e-238 mcpA NT chemotaxis protein
ACFBBGHA_03919 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
ACFBBGHA_03920 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
ACFBBGHA_03921 1.4e-275 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
ACFBBGHA_03922 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
ACFBBGHA_03923 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
ACFBBGHA_03924 3.3e-183 ygjR S Oxidoreductase
ACFBBGHA_03925 1.3e-194 yubA S transporter activity
ACFBBGHA_03926 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
ACFBBGHA_03928 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
ACFBBGHA_03929 2.2e-274 yubD P Major Facilitator Superfamily
ACFBBGHA_03930 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
ACFBBGHA_03931 1e-38 yiaA S yiaA/B two helix domain
ACFBBGHA_03932 7.9e-236 ktrB P Potassium
ACFBBGHA_03933 3.2e-121 ktrA P COG0569 K transport systems, NAD-binding component
ACFBBGHA_03934 2.2e-91 yuaB
ACFBBGHA_03935 5.5e-95 yuaC K Belongs to the GbsR family
ACFBBGHA_03936 1.8e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
ACFBBGHA_03937 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
ACFBBGHA_03938 7.9e-108 yuaD
ACFBBGHA_03939 3.9e-84 yuaE S DinB superfamily
ACFBBGHA_03940 1e-74 yuaF OU Membrane protein implicated in regulation of membrane protease activity
ACFBBGHA_03941 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
ACFBBGHA_03942 3.2e-92 M1-753 M FR47-like protein
ACFBBGHA_03943 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
ACFBBGHA_03944 2.9e-76 ctsR K Belongs to the CtsR family
ACFBBGHA_03945 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
ACFBBGHA_03946 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
ACFBBGHA_03947 0.0 clpC O Belongs to the ClpA ClpB family
ACFBBGHA_03948 8.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACFBBGHA_03949 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ACFBBGHA_03950 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
ACFBBGHA_03951 9.4e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
ACFBBGHA_03952 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
ACFBBGHA_03953 3.3e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACFBBGHA_03954 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
ACFBBGHA_03955 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
ACFBBGHA_03956 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ACFBBGHA_03957 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACFBBGHA_03958 1.2e-88 yacP S RNA-binding protein containing a PIN domain
ACFBBGHA_03959 4.4e-115 sigH K Belongs to the sigma-70 factor family
ACFBBGHA_03960 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
ACFBBGHA_03961 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
ACFBBGHA_03962 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACFBBGHA_03963 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
ACFBBGHA_03964 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACFBBGHA_03965 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
ACFBBGHA_03966 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
ACFBBGHA_03967 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACFBBGHA_03968 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACFBBGHA_03969 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
ACFBBGHA_03970 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACFBBGHA_03971 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
ACFBBGHA_03972 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACFBBGHA_03973 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACFBBGHA_03974 3.1e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
ACFBBGHA_03975 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
ACFBBGHA_03976 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACFBBGHA_03977 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
ACFBBGHA_03978 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
ACFBBGHA_03979 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACFBBGHA_03980 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACFBBGHA_03981 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ACFBBGHA_03982 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACFBBGHA_03983 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACFBBGHA_03984 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
ACFBBGHA_03985 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACFBBGHA_03986 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACFBBGHA_03987 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACFBBGHA_03988 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACFBBGHA_03989 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACFBBGHA_03990 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACFBBGHA_03991 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACFBBGHA_03992 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACFBBGHA_03993 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACFBBGHA_03994 1.9e-23 rpmD J Ribosomal protein L30
ACFBBGHA_03995 1.8e-72 rplO J binds to the 23S rRNA
ACFBBGHA_03996 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
ACFBBGHA_03997 4.8e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
ACFBBGHA_03998 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
ACFBBGHA_03999 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACFBBGHA_04000 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
ACFBBGHA_04001 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACFBBGHA_04002 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACFBBGHA_04003 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACFBBGHA_04004 3.6e-58 rplQ J Ribosomal protein L17
ACFBBGHA_04005 1.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACFBBGHA_04006 2.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACFBBGHA_04007 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACFBBGHA_04008 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
ACFBBGHA_04009 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACFBBGHA_04010 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
ACFBBGHA_04011 8.2e-145 ybaJ Q Methyltransferase domain
ACFBBGHA_04012 9.7e-66 ybaK S Protein of unknown function (DUF2521)
ACFBBGHA_04013 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
ACFBBGHA_04014 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
ACFBBGHA_04015 1.2e-84 gerD
ACFBBGHA_04016 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
ACFBBGHA_04017 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
ACFBBGHA_04018 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_04019 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_04020 7e-95 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
ACFBBGHA_04021 1.8e-35 bofA S Sigma-K factor-processing regulatory protein BofA
ACFBBGHA_04022 7.9e-32 yaaL S Protein of unknown function (DUF2508)
ACFBBGHA_04023 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACFBBGHA_04024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ACFBBGHA_04025 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACFBBGHA_04026 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
ACFBBGHA_04027 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
ACFBBGHA_04028 1.2e-212 yaaH M Glycoside Hydrolase Family
ACFBBGHA_04029 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
ACFBBGHA_04030 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
ACFBBGHA_04031 1.3e-09
ACFBBGHA_04032 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACFBBGHA_04033 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ACFBBGHA_04034 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACFBBGHA_04035 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
ACFBBGHA_04036 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
ACFBBGHA_04037 8.7e-181 yaaC S YaaC-like Protein
ACFBBGHA_04038 3.4e-31 csfB S Inhibitor of sigma-G Gin
ACFBBGHA_04039 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
ACFBBGHA_04040 2.9e-202 yaaN P Belongs to the TelA family
ACFBBGHA_04041 1e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
ACFBBGHA_04042 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACFBBGHA_04043 2.2e-54 yaaQ S protein conserved in bacteria
ACFBBGHA_04044 1.5e-71 yaaR S protein conserved in bacteria
ACFBBGHA_04045 2.2e-182 holB 2.7.7.7 L DNA polymerase III
ACFBBGHA_04046 2.1e-146 yaaT S stage 0 sporulation protein
ACFBBGHA_04047 4.8e-31 yabA L Involved in initiation control of chromosome replication
ACFBBGHA_04048 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
ACFBBGHA_04049 1.5e-49 yazA L endonuclease containing a URI domain
ACFBBGHA_04050 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACFBBGHA_04051 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
ACFBBGHA_04052 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACFBBGHA_04053 4.5e-143 tatD L hydrolase, TatD
ACFBBGHA_04054 5.8e-167 rpfB GH23 T protein conserved in bacteria
ACFBBGHA_04055 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ACFBBGHA_04056 4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
ACFBBGHA_04057 1.8e-135 yabG S peptidase
ACFBBGHA_04058 7.8e-39 veg S protein conserved in bacteria
ACFBBGHA_04059 8.3e-27 sspF S DNA topological change
ACFBBGHA_04060 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACFBBGHA_04061 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
ACFBBGHA_04062 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
ACFBBGHA_04063 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
ACFBBGHA_04064 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACFBBGHA_04065 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACFBBGHA_04066 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACFBBGHA_04067 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
ACFBBGHA_04068 2.4e-39 yabK S Peptide ABC transporter permease
ACFBBGHA_04069 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACFBBGHA_04070 1.5e-92 spoVT K stage V sporulation protein
ACFBBGHA_04071 1.5e-286 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
ACFBBGHA_04072 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
ACFBBGHA_04073 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
ACFBBGHA_04074 1.5e-49 yabP S Sporulation protein YabP
ACFBBGHA_04075 3.9e-108 yabQ S spore cortex biosynthesis protein
ACFBBGHA_04076 1.1e-44 divIC D Septum formation initiator
ACFBBGHA_04077 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
ACFBBGHA_04080 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
ACFBBGHA_04081 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
ACFBBGHA_04082 1.2e-183 KLT serine threonine protein kinase
ACFBBGHA_04083 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
ACFBBGHA_04084 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
ACFBBGHA_04085 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACFBBGHA_04086 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ACFBBGHA_04087 4.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACFBBGHA_04088 2.9e-151 yacD 5.2.1.8 O peptidyl-prolyl isomerase
ACFBBGHA_04089 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
ACFBBGHA_04090 4.8e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACFBBGHA_04091 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
ACFBBGHA_04092 1.3e-165 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
ACFBBGHA_04093 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACFBBGHA_04094 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACFBBGHA_04095 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACFBBGHA_04096 4.1e-30 yazB K transcriptional
ACFBBGHA_04097 9.2e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACFBBGHA_04098 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)