ORF_ID e_value Gene_name EC_number CAZy COGs Description
COEIJKGJ_00001 3.4e-39 S COG NOG14552 non supervised orthologous group
COEIJKGJ_00006 2e-08
COEIJKGJ_00015 2e-08
COEIJKGJ_00022 1.3e-09
COEIJKGJ_00023 7.8e-08
COEIJKGJ_00032 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COEIJKGJ_00033 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COEIJKGJ_00034 6.4e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
COEIJKGJ_00035 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
COEIJKGJ_00036 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COEIJKGJ_00037 9.9e-77 tspO T membrane
COEIJKGJ_00038 1.8e-206 cotI S Spore coat protein
COEIJKGJ_00039 1.8e-217 cotSA M Glycosyl transferases group 1
COEIJKGJ_00040 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
COEIJKGJ_00042 3.6e-235 ytcC M Glycosyltransferase Family 4
COEIJKGJ_00043 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
COEIJKGJ_00044 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COEIJKGJ_00045 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
COEIJKGJ_00046 2.6e-132 dksA T COG1734 DnaK suppressor protein
COEIJKGJ_00047 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
COEIJKGJ_00048 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
COEIJKGJ_00049 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
COEIJKGJ_00050 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
COEIJKGJ_00051 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
COEIJKGJ_00052 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
COEIJKGJ_00053 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
COEIJKGJ_00054 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
COEIJKGJ_00055 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
COEIJKGJ_00056 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
COEIJKGJ_00057 1.1e-24 S Domain of Unknown Function (DUF1540)
COEIJKGJ_00058 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
COEIJKGJ_00059 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
COEIJKGJ_00060 3.6e-41 rpmE2 J Ribosomal protein L31
COEIJKGJ_00061 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
COEIJKGJ_00062 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COEIJKGJ_00063 2.4e-72 ytkA S YtkA-like
COEIJKGJ_00065 2.1e-76 dps P Belongs to the Dps family
COEIJKGJ_00066 5.4e-63 ytkC S Bacteriophage holin family
COEIJKGJ_00067 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
COEIJKGJ_00068 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
COEIJKGJ_00069 1.4e-144 ytlC P ABC transporter
COEIJKGJ_00070 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
COEIJKGJ_00071 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
COEIJKGJ_00072 1.2e-38 ytmB S Protein of unknown function (DUF2584)
COEIJKGJ_00073 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
COEIJKGJ_00074 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COEIJKGJ_00075 0.0 asnB 6.3.5.4 E Asparagine synthase
COEIJKGJ_00076 1.1e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
COEIJKGJ_00077 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
COEIJKGJ_00078 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
COEIJKGJ_00079 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
COEIJKGJ_00080 3.3e-106 ytqB J Putative rRNA methylase
COEIJKGJ_00081 2.1e-190 yhcC S Fe-S oxidoreductase
COEIJKGJ_00082 6.7e-41 ytzC S Protein of unknown function (DUF2524)
COEIJKGJ_00084 5.1e-66 ytrA K GntR family transcriptional regulator
COEIJKGJ_00085 4.2e-161 ytrB P abc transporter atp-binding protein
COEIJKGJ_00086 8.3e-166 P ABC-2 family transporter protein
COEIJKGJ_00087 5.9e-148
COEIJKGJ_00088 3.1e-127 ytrE V ABC transporter, ATP-binding protein
COEIJKGJ_00089 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
COEIJKGJ_00090 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_00091 1.5e-183 T PhoQ Sensor
COEIJKGJ_00092 1.1e-138 bceA V ABC transporter, ATP-binding protein
COEIJKGJ_00093 0.0 bceB V ABC transporter (permease)
COEIJKGJ_00094 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
COEIJKGJ_00095 7.3e-209 yttB EGP Major facilitator Superfamily
COEIJKGJ_00096 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
COEIJKGJ_00097 7.7e-55 ytvB S Protein of unknown function (DUF4257)
COEIJKGJ_00098 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COEIJKGJ_00099 2.1e-51 ytwF P Sulfurtransferase
COEIJKGJ_00100 5.8e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
COEIJKGJ_00101 1.1e-142 amyC P ABC transporter (permease)
COEIJKGJ_00102 1.4e-167 amyD P ABC transporter
COEIJKGJ_00103 1.9e-247 msmE G Bacterial extracellular solute-binding protein
COEIJKGJ_00104 1.5e-189 msmR K Transcriptional regulator
COEIJKGJ_00105 7.8e-171 ytaP S Acetyl xylan esterase (AXE1)
COEIJKGJ_00106 3.1e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
COEIJKGJ_00107 3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
COEIJKGJ_00108 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
COEIJKGJ_00109 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
COEIJKGJ_00110 5.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
COEIJKGJ_00111 1.7e-221 bioI 1.14.14.46 C Cytochrome P450
COEIJKGJ_00112 1.2e-135 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
COEIJKGJ_00113 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
COEIJKGJ_00114 1.8e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
COEIJKGJ_00115 0.0 ytdP K Transcriptional regulator
COEIJKGJ_00116 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
COEIJKGJ_00117 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
COEIJKGJ_00118 4.6e-73 yteS G transport
COEIJKGJ_00119 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
COEIJKGJ_00120 4.8e-117 yteU S Integral membrane protein
COEIJKGJ_00121 3.1e-26 yteV S Sporulation protein Cse60
COEIJKGJ_00122 7.5e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
COEIJKGJ_00123 1.4e-231 ytfP S HI0933-like protein
COEIJKGJ_00124 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COEIJKGJ_00125 1.8e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COEIJKGJ_00126 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
COEIJKGJ_00127 9e-130 ythP V ABC transporter
COEIJKGJ_00128 1.5e-203 ythQ U Bacterial ABC transporter protein EcsB
COEIJKGJ_00129 7.2e-226 pbuO S permease
COEIJKGJ_00130 7.1e-272 pepV 3.5.1.18 E Dipeptidase
COEIJKGJ_00131 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COEIJKGJ_00132 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
COEIJKGJ_00133 1.3e-165 ytlQ
COEIJKGJ_00134 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
COEIJKGJ_00135 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
COEIJKGJ_00136 1e-150 ytmP 2.7.1.89 M Phosphotransferase
COEIJKGJ_00137 2e-45 ytzH S YtzH-like protein
COEIJKGJ_00138 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COEIJKGJ_00139 1.8e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
COEIJKGJ_00140 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
COEIJKGJ_00141 2.2e-51 ytzB S small secreted protein
COEIJKGJ_00142 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
COEIJKGJ_00143 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
COEIJKGJ_00144 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COEIJKGJ_00145 9.8e-149 ytpQ S Belongs to the UPF0354 family
COEIJKGJ_00146 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COEIJKGJ_00147 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
COEIJKGJ_00148 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COEIJKGJ_00149 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COEIJKGJ_00150 6.6e-17 ytxH S COG4980 Gas vesicle protein
COEIJKGJ_00151 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
COEIJKGJ_00152 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
COEIJKGJ_00153 3.8e-182 ccpA K catabolite control protein A
COEIJKGJ_00154 2.1e-146 motA N flagellar motor
COEIJKGJ_00155 1.4e-125 motS N Flagellar motor protein
COEIJKGJ_00156 1.6e-224 acuC BQ histone deacetylase
COEIJKGJ_00157 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
COEIJKGJ_00158 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
COEIJKGJ_00159 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
COEIJKGJ_00160 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COEIJKGJ_00162 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COEIJKGJ_00163 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
COEIJKGJ_00164 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
COEIJKGJ_00165 3.4e-109 yttP K Transcriptional regulator
COEIJKGJ_00166 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
COEIJKGJ_00167 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COEIJKGJ_00168 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
COEIJKGJ_00169 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
COEIJKGJ_00170 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COEIJKGJ_00171 2e-29 sspB S spore protein
COEIJKGJ_00172 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
COEIJKGJ_00173 0.0 ytcJ S amidohydrolase
COEIJKGJ_00174 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COEIJKGJ_00175 7.1e-181 sppA OU signal peptide peptidase SppA
COEIJKGJ_00176 1.3e-87 yteJ S RDD family
COEIJKGJ_00177 5.6e-116 ytfI S Protein of unknown function (DUF2953)
COEIJKGJ_00178 8.7e-70 ytfJ S Sporulation protein YtfJ
COEIJKGJ_00179 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COEIJKGJ_00180 7e-165 ytxK 2.1.1.72 L DNA methylase
COEIJKGJ_00181 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COEIJKGJ_00182 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
COEIJKGJ_00183 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
COEIJKGJ_00184 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
COEIJKGJ_00186 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_00187 1.7e-130 ytkL S Belongs to the UPF0173 family
COEIJKGJ_00188 2.9e-173 ytlI K LysR substrate binding domain
COEIJKGJ_00189 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
COEIJKGJ_00190 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
COEIJKGJ_00191 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
COEIJKGJ_00192 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
COEIJKGJ_00193 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
COEIJKGJ_00194 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
COEIJKGJ_00195 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COEIJKGJ_00196 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
COEIJKGJ_00197 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COEIJKGJ_00198 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
COEIJKGJ_00199 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
COEIJKGJ_00200 1.2e-158 ytnM S membrane transporter protein
COEIJKGJ_00201 8e-241 ytoI K transcriptional regulator containing CBS domains
COEIJKGJ_00202 2.4e-47 ytpI S YtpI-like protein
COEIJKGJ_00203 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
COEIJKGJ_00204 9.2e-29
COEIJKGJ_00205 2.4e-68 ytrI
COEIJKGJ_00206 3.2e-56 ytrH S Sporulation protein YtrH
COEIJKGJ_00207 0.0 dnaE 2.7.7.7 L DNA polymerase
COEIJKGJ_00208 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
COEIJKGJ_00209 3.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COEIJKGJ_00210 8.1e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
COEIJKGJ_00211 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COEIJKGJ_00212 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COEIJKGJ_00213 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
COEIJKGJ_00214 9.9e-192 ytvI S sporulation integral membrane protein YtvI
COEIJKGJ_00215 4.7e-71 yeaL S membrane
COEIJKGJ_00216 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
COEIJKGJ_00217 1.8e-242 icd 1.1.1.42 C isocitrate
COEIJKGJ_00218 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
COEIJKGJ_00219 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_00220 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
COEIJKGJ_00221 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COEIJKGJ_00222 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COEIJKGJ_00223 1.1e-107 ytaF P Probably functions as a manganese efflux pump
COEIJKGJ_00224 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COEIJKGJ_00225 8.9e-161 ytbE S reductase
COEIJKGJ_00226 4.9e-205 ytbD EGP Major facilitator Superfamily
COEIJKGJ_00227 9.9e-67 ytcD K Transcriptional regulator
COEIJKGJ_00228 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COEIJKGJ_00229 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
COEIJKGJ_00230 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COEIJKGJ_00231 3.5e-266 dnaB L Membrane attachment protein
COEIJKGJ_00232 3e-173 dnaI L Primosomal protein DnaI
COEIJKGJ_00233 4.9e-111 ytxB S SNARE associated Golgi protein
COEIJKGJ_00234 3.8e-159 ytxC S YtxC-like family
COEIJKGJ_00235 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COEIJKGJ_00236 1.5e-149 ysaA S HAD-hyrolase-like
COEIJKGJ_00237 0.0 lytS 2.7.13.3 T Histidine kinase
COEIJKGJ_00238 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
COEIJKGJ_00239 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
COEIJKGJ_00240 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
COEIJKGJ_00242 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COEIJKGJ_00243 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COEIJKGJ_00244 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COEIJKGJ_00245 7.5e-45 ysdA S Membrane
COEIJKGJ_00246 9.2e-68 ysdB S Sigma-w pathway protein YsdB
COEIJKGJ_00247 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
COEIJKGJ_00248 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
COEIJKGJ_00249 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
COEIJKGJ_00250 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
COEIJKGJ_00251 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
COEIJKGJ_00252 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
COEIJKGJ_00253 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
COEIJKGJ_00254 2e-252 araN G carbohydrate transport
COEIJKGJ_00255 4.2e-167 araP G carbohydrate transport
COEIJKGJ_00256 3.8e-143 araQ G transport system permease
COEIJKGJ_00257 1.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
COEIJKGJ_00258 0.0 cstA T Carbon starvation protein
COEIJKGJ_00259 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
COEIJKGJ_00260 5.8e-255 glcF C Glycolate oxidase
COEIJKGJ_00261 8.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
COEIJKGJ_00262 9.2e-206 ysfB KT regulator
COEIJKGJ_00263 5.8e-32 sspI S Belongs to the SspI family
COEIJKGJ_00264 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COEIJKGJ_00265 2.3e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COEIJKGJ_00266 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COEIJKGJ_00267 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COEIJKGJ_00268 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
COEIJKGJ_00269 1.3e-85 cvpA S membrane protein, required for colicin V production
COEIJKGJ_00270 0.0 polX L COG1796 DNA polymerase IV (family X)
COEIJKGJ_00271 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COEIJKGJ_00272 7.3e-68 yshE S membrane
COEIJKGJ_00273 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COEIJKGJ_00274 2.7e-100 fadR K Transcriptional regulator
COEIJKGJ_00275 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
COEIJKGJ_00276 4.5e-135 etfB C Electron transfer flavoprotein
COEIJKGJ_00277 2.1e-177 etfA C Electron transfer flavoprotein
COEIJKGJ_00279 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
COEIJKGJ_00280 2e-52 trxA O Belongs to the thioredoxin family
COEIJKGJ_00281 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COEIJKGJ_00282 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
COEIJKGJ_00283 1.2e-79 yslB S Protein of unknown function (DUF2507)
COEIJKGJ_00284 2.4e-107 sdhC C succinate dehydrogenase
COEIJKGJ_00285 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
COEIJKGJ_00286 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
COEIJKGJ_00287 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
COEIJKGJ_00288 3.3e-30 gerE K Transcriptional regulator
COEIJKGJ_00289 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
COEIJKGJ_00290 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COEIJKGJ_00291 2.9e-196 gerM S COG5401 Spore germination protein
COEIJKGJ_00292 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
COEIJKGJ_00293 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COEIJKGJ_00294 1.4e-92 ysnB S Phosphoesterase
COEIJKGJ_00296 9.1e-134 ysnF S protein conserved in bacteria
COEIJKGJ_00297 7.6e-82 ysnE K acetyltransferase
COEIJKGJ_00299 0.0 ilvB 2.2.1.6 E Acetolactate synthase
COEIJKGJ_00300 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
COEIJKGJ_00301 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
COEIJKGJ_00302 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
COEIJKGJ_00303 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
COEIJKGJ_00304 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COEIJKGJ_00305 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
COEIJKGJ_00306 2.3e-187 ysoA H Tetratricopeptide repeat
COEIJKGJ_00307 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COEIJKGJ_00308 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COEIJKGJ_00309 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
COEIJKGJ_00310 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
COEIJKGJ_00311 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
COEIJKGJ_00312 1.4e-89 ysxD
COEIJKGJ_00313 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
COEIJKGJ_00314 3.6e-146 hemX O cytochrome C
COEIJKGJ_00315 9.6e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
COEIJKGJ_00316 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
COEIJKGJ_00317 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
COEIJKGJ_00318 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
COEIJKGJ_00319 2.2e-222 spoVID M stage VI sporulation protein D
COEIJKGJ_00320 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
COEIJKGJ_00321 1.6e-25
COEIJKGJ_00322 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COEIJKGJ_00323 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COEIJKGJ_00324 8.3e-126 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
COEIJKGJ_00325 8.4e-166 spoIIB S Sporulation related domain
COEIJKGJ_00326 8.3e-102 maf D septum formation protein Maf
COEIJKGJ_00327 1.3e-125 radC E Belongs to the UPF0758 family
COEIJKGJ_00328 1.8e-184 mreB D Rod shape-determining protein MreB
COEIJKGJ_00329 2.8e-157 mreC M Involved in formation and maintenance of cell shape
COEIJKGJ_00330 1.4e-84 mreD M shape-determining protein
COEIJKGJ_00331 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
COEIJKGJ_00332 4.7e-143 minD D Belongs to the ParA family
COEIJKGJ_00333 9.3e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
COEIJKGJ_00334 9.2e-161 spoIVFB S Stage IV sporulation protein
COEIJKGJ_00335 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
COEIJKGJ_00336 4.1e-56 ysxB J ribosomal protein
COEIJKGJ_00337 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COEIJKGJ_00338 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
COEIJKGJ_00339 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COEIJKGJ_00340 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
COEIJKGJ_00341 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
COEIJKGJ_00342 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
COEIJKGJ_00343 4.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
COEIJKGJ_00344 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
COEIJKGJ_00345 1.9e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
COEIJKGJ_00346 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
COEIJKGJ_00347 8.3e-157 safA M spore coat assembly protein SafA
COEIJKGJ_00348 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
COEIJKGJ_00349 1e-125 yebC K transcriptional regulatory protein
COEIJKGJ_00350 4.5e-261 alsT E Sodium alanine symporter
COEIJKGJ_00351 1.3e-50 S Family of unknown function (DUF5412)
COEIJKGJ_00353 6.5e-119 yrzF T serine threonine protein kinase
COEIJKGJ_00354 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
COEIJKGJ_00355 4.5e-252 csbX EGP Major facilitator Superfamily
COEIJKGJ_00356 4.8e-93 bofC S BofC C-terminal domain
COEIJKGJ_00357 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COEIJKGJ_00358 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COEIJKGJ_00359 2.6e-18 yrzS S Protein of unknown function (DUF2905)
COEIJKGJ_00360 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
COEIJKGJ_00361 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COEIJKGJ_00362 1.1e-38 yajC U Preprotein translocase subunit YajC
COEIJKGJ_00363 2.2e-73 yrzE S Protein of unknown function (DUF3792)
COEIJKGJ_00364 3e-111 yrbG S membrane
COEIJKGJ_00365 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COEIJKGJ_00366 9.4e-49 yrzD S Post-transcriptional regulator
COEIJKGJ_00367 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
COEIJKGJ_00368 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
COEIJKGJ_00369 3e-48 yrvD S Lipopolysaccharide assembly protein A domain
COEIJKGJ_00370 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COEIJKGJ_00371 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COEIJKGJ_00372 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COEIJKGJ_00373 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COEIJKGJ_00374 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
COEIJKGJ_00376 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
COEIJKGJ_00377 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
COEIJKGJ_00378 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
COEIJKGJ_00379 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
COEIJKGJ_00380 1.2e-70 cymR K Transcriptional regulator
COEIJKGJ_00381 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
COEIJKGJ_00382 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COEIJKGJ_00383 1.4e-15 S COG0457 FOG TPR repeat
COEIJKGJ_00384 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COEIJKGJ_00385 2.5e-80 yrrD S protein conserved in bacteria
COEIJKGJ_00386 9.8e-31 yrzR
COEIJKGJ_00387 8e-08 S Protein of unknown function (DUF3918)
COEIJKGJ_00388 7.6e-107 glnP P ABC transporter
COEIJKGJ_00389 8e-109 gluC P ABC transporter
COEIJKGJ_00390 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
COEIJKGJ_00391 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
COEIJKGJ_00392 2.7e-170 yrrI S AI-2E family transporter
COEIJKGJ_00393 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COEIJKGJ_00394 1.7e-41 yrzL S Belongs to the UPF0297 family
COEIJKGJ_00395 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COEIJKGJ_00396 1.2e-45 yrzB S Belongs to the UPF0473 family
COEIJKGJ_00397 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COEIJKGJ_00398 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
COEIJKGJ_00399 3.9e-173 yegQ O Peptidase U32
COEIJKGJ_00400 2.7e-246 yegQ O COG0826 Collagenase and related proteases
COEIJKGJ_00401 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
COEIJKGJ_00402 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COEIJKGJ_00403 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
COEIJKGJ_00404 2.5e-60 yrrS S Protein of unknown function (DUF1510)
COEIJKGJ_00405 1e-25 yrzA S Protein of unknown function (DUF2536)
COEIJKGJ_00406 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
COEIJKGJ_00407 1.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COEIJKGJ_00408 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
COEIJKGJ_00409 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COEIJKGJ_00410 4.6e-35 yrhC S YrhC-like protein
COEIJKGJ_00411 1.4e-78 yrhD S Protein of unknown function (DUF1641)
COEIJKGJ_00412 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
COEIJKGJ_00413 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
COEIJKGJ_00414 1.8e-142 focA P Formate nitrite
COEIJKGJ_00417 7.2e-95 yrhH Q methyltransferase
COEIJKGJ_00418 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
COEIJKGJ_00419 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
COEIJKGJ_00420 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
COEIJKGJ_00421 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
COEIJKGJ_00422 9.4e-117 S ATPases associated with a variety of cellular activities
COEIJKGJ_00423 5.7e-64 S ABC-2 family transporter protein
COEIJKGJ_00424 8.3e-63 S ABC-2 family transporter protein
COEIJKGJ_00425 7.2e-104 Q TIGRFAM amino acid adenylation domain
COEIJKGJ_00426 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
COEIJKGJ_00427 1.5e-180 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
COEIJKGJ_00428 1.2e-100 EF ATP-grasp domain
COEIJKGJ_00429 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
COEIJKGJ_00430 1.5e-52 S dehydrogenases and related proteins
COEIJKGJ_00431 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
COEIJKGJ_00432 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
COEIJKGJ_00433 1e-18 yrhK S YrhK-like protein
COEIJKGJ_00434 0.0 yrhL I Acyltransferase family
COEIJKGJ_00435 3.8e-151 rsiV S Protein of unknown function (DUF3298)
COEIJKGJ_00436 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_00437 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
COEIJKGJ_00438 3.6e-106 yrhP E LysE type translocator
COEIJKGJ_00439 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
COEIJKGJ_00440 0.0 levR K PTS system fructose IIA component
COEIJKGJ_00441 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
COEIJKGJ_00442 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
COEIJKGJ_00443 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
COEIJKGJ_00444 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
COEIJKGJ_00445 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
COEIJKGJ_00446 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
COEIJKGJ_00447 3.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
COEIJKGJ_00448 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
COEIJKGJ_00449 4.3e-47 yraB K helix_turn_helix, mercury resistance
COEIJKGJ_00450 1.1e-49 yraD M Spore coat protein
COEIJKGJ_00451 2.6e-26 yraE
COEIJKGJ_00452 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
COEIJKGJ_00453 6.4e-63 yraF M Spore coat protein
COEIJKGJ_00454 5.3e-37 yraG
COEIJKGJ_00455 1.3e-66 E Glyoxalase-like domain
COEIJKGJ_00456 2.4e-61 T sh3 domain protein
COEIJKGJ_00457 1.7e-60 T sh3 domain protein
COEIJKGJ_00458 3.2e-155 S Alpha beta hydrolase
COEIJKGJ_00459 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COEIJKGJ_00460 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
COEIJKGJ_00462 1.6e-205 yraM S PrpF protein
COEIJKGJ_00463 3.4e-163 yraN K Transcriptional regulator
COEIJKGJ_00464 3.4e-223 yraO C Citrate transporter
COEIJKGJ_00465 1.3e-187 yrpG C Aldo/keto reductase family
COEIJKGJ_00466 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_00467 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
COEIJKGJ_00469 1.6e-123 yrpD S Domain of unknown function, YrpD
COEIJKGJ_00470 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COEIJKGJ_00471 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
COEIJKGJ_00472 4.2e-166 aadK G Streptomycin adenylyltransferase
COEIJKGJ_00473 2.4e-89 yrdA S DinB family
COEIJKGJ_00474 3.3e-57 S Protein of unknown function (DUF2568)
COEIJKGJ_00475 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
COEIJKGJ_00476 1.1e-40 yrdF K ribonuclease inhibitor
COEIJKGJ_00477 5.3e-78 bkdR K helix_turn_helix ASNC type
COEIJKGJ_00478 9.6e-138 azlC E AzlC protein
COEIJKGJ_00479 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
COEIJKGJ_00480 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
COEIJKGJ_00481 5e-162 gltR K LysR substrate binding domain
COEIJKGJ_00482 1.3e-66 yodA S tautomerase
COEIJKGJ_00483 4e-149 czcD P COG1230 Co Zn Cd efflux system component
COEIJKGJ_00484 2.3e-198 trkA P Oxidoreductase
COEIJKGJ_00485 3e-159 yrdQ K Transcriptional regulator
COEIJKGJ_00486 1.6e-169 yrdR EG EamA-like transporter family
COEIJKGJ_00487 3.9e-16 S YrzO-like protein
COEIJKGJ_00488 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
COEIJKGJ_00489 5.9e-82 bltD 2.3.1.57 K FR47-like protein
COEIJKGJ_00490 3.9e-210 blt EGP Major facilitator Superfamily
COEIJKGJ_00491 4.2e-147 bltR K helix_turn_helix, mercury resistance
COEIJKGJ_00492 5.5e-106 yrkC G Cupin domain
COEIJKGJ_00493 7.8e-39 yrkD S protein conserved in bacteria
COEIJKGJ_00494 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
COEIJKGJ_00495 2.3e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
COEIJKGJ_00496 9.3e-206 yrkH P Rhodanese Homology Domain
COEIJKGJ_00497 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
COEIJKGJ_00498 5.4e-112 yrkJ S membrane transporter protein
COEIJKGJ_00499 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
COEIJKGJ_00500 2e-215 mepA V Multidrug transporter MatE
COEIJKGJ_00501 3.6e-112 tetR3 K Transcriptional regulator
COEIJKGJ_00502 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COEIJKGJ_00503 1.2e-94 yqaB E IrrE N-terminal-like domain
COEIJKGJ_00505 1.2e-97 adk 2.7.4.3 F adenylate kinase activity
COEIJKGJ_00507 1.1e-32 K sequence-specific DNA binding
COEIJKGJ_00508 1.2e-17 K Helix-turn-helix XRE-family like proteins
COEIJKGJ_00510 1.2e-103
COEIJKGJ_00514 1.4e-162 yqaJ L YqaJ-like viral recombinase domain
COEIJKGJ_00515 2.5e-155 recT L RecT family
COEIJKGJ_00516 1e-122 3.1.3.16 L DnaD domain protein
COEIJKGJ_00517 5.9e-168 xkdC L IstB-like ATP binding protein
COEIJKGJ_00519 7.2e-74 rusA L Endodeoxyribonuclease RusA
COEIJKGJ_00520 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
COEIJKGJ_00521 1.6e-166
COEIJKGJ_00522 6.5e-81 L Transposase
COEIJKGJ_00524 6.3e-107 yqaS L DNA packaging
COEIJKGJ_00525 2.4e-253 S phage terminase, large subunit
COEIJKGJ_00526 3.3e-286 yqbA S portal protein
COEIJKGJ_00527 1.4e-151 S Phage Mu protein F like protein
COEIJKGJ_00528 6.1e-63
COEIJKGJ_00529 2.8e-118 yqbD 2.1.1.72 L Putative phage serine protease XkdF
COEIJKGJ_00530 7.1e-167 xkdG S Phage capsid family
COEIJKGJ_00531 1.6e-46 S YqbF, hypothetical protein domain
COEIJKGJ_00532 3.9e-66 S Protein of unknown function (DUF3199)
COEIJKGJ_00533 1.2e-61 yqbH S Domain of unknown function (DUF3599)
COEIJKGJ_00534 3.3e-86 S Bacteriophage HK97-gp10, putative tail-component
COEIJKGJ_00535 7.8e-76
COEIJKGJ_00536 1.8e-24
COEIJKGJ_00537 6.3e-252 xkdK S Phage tail sheath C-terminal domain
COEIJKGJ_00538 3.6e-76 xkdM S Phage tail tube protein
COEIJKGJ_00539 1.2e-66 S Phage XkdN-like tail assembly chaperone protein, TAC
COEIJKGJ_00540 0.0 xkdO L Transglycosylase SLT domain
COEIJKGJ_00541 7.6e-113 xkdP S Lysin motif
COEIJKGJ_00542 4.2e-178 yqbQ 3.2.1.96 G NLP P60 protein
COEIJKGJ_00543 2.7e-31 xkdR S Protein of unknown function (DUF2577)
COEIJKGJ_00544 1.9e-66 xkdS S Protein of unknown function (DUF2634)
COEIJKGJ_00545 5.5e-184 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
COEIJKGJ_00546 7.1e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
COEIJKGJ_00547 9.6e-40
COEIJKGJ_00548 4.2e-219
COEIJKGJ_00549 4.1e-56 xkdW S XkdW protein
COEIJKGJ_00550 3.7e-10
COEIJKGJ_00551 3e-159 xepA
COEIJKGJ_00552 2.6e-68 S Bacteriophage holin family
COEIJKGJ_00553 5.9e-133 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
COEIJKGJ_00556 4.6e-100 S Suppressor of fused protein (SUFU)
COEIJKGJ_00557 3.7e-47
COEIJKGJ_00558 1.3e-14 S SMI1-KNR4 cell-wall
COEIJKGJ_00560 1.1e-26 yokK S SMI1 / KNR4 family
COEIJKGJ_00561 6e-228 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
COEIJKGJ_00562 1e-70 K MerR family transcriptional regulator
COEIJKGJ_00563 1.3e-138 yvgN 1.1.1.346 S Reductase
COEIJKGJ_00564 8.4e-130 S Aspartate phosphatase response regulator
COEIJKGJ_00566 1.3e-123 yecA E amino acid
COEIJKGJ_00567 1.5e-105 K Transcriptional regulator
COEIJKGJ_00568 4.6e-277 cisA2 L Recombinase
COEIJKGJ_00569 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COEIJKGJ_00570 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
COEIJKGJ_00571 2e-132 yqeB
COEIJKGJ_00572 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
COEIJKGJ_00573 2.3e-105 yqeD S SNARE associated Golgi protein
COEIJKGJ_00574 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COEIJKGJ_00575 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
COEIJKGJ_00577 5.3e-95 yqeG S hydrolase of the HAD superfamily
COEIJKGJ_00578 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
COEIJKGJ_00579 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COEIJKGJ_00580 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
COEIJKGJ_00581 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COEIJKGJ_00582 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
COEIJKGJ_00583 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COEIJKGJ_00584 2.9e-139 yqeM Q Methyltransferase
COEIJKGJ_00585 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COEIJKGJ_00586 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
COEIJKGJ_00587 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
COEIJKGJ_00588 0.0 comEC S Competence protein ComEC
COEIJKGJ_00589 4.1e-15 S YqzM-like protein
COEIJKGJ_00590 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
COEIJKGJ_00591 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
COEIJKGJ_00592 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
COEIJKGJ_00593 4.5e-222 spoIIP M stage II sporulation protein P
COEIJKGJ_00594 7.2e-53 yqxA S Protein of unknown function (DUF3679)
COEIJKGJ_00595 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COEIJKGJ_00596 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
COEIJKGJ_00597 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COEIJKGJ_00598 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COEIJKGJ_00599 0.0 dnaK O Heat shock 70 kDa protein
COEIJKGJ_00600 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COEIJKGJ_00601 6e-174 prmA J Methylates ribosomal protein L11
COEIJKGJ_00602 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COEIJKGJ_00603 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
COEIJKGJ_00604 2.3e-157 yqeW P COG1283 Na phosphate symporter
COEIJKGJ_00605 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COEIJKGJ_00606 2.5e-61 yqeY S Yqey-like protein
COEIJKGJ_00607 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
COEIJKGJ_00608 4.3e-122 yqfA S UPF0365 protein
COEIJKGJ_00609 2.4e-21 yqfB
COEIJKGJ_00610 2.7e-45 yqfC S sporulation protein YqfC
COEIJKGJ_00611 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
COEIJKGJ_00612 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
COEIJKGJ_00614 0.0 yqfF S membrane-associated HD superfamily hydrolase
COEIJKGJ_00615 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COEIJKGJ_00616 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
COEIJKGJ_00617 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
COEIJKGJ_00618 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COEIJKGJ_00619 8.4e-19 S YqzL-like protein
COEIJKGJ_00620 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
COEIJKGJ_00621 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COEIJKGJ_00622 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COEIJKGJ_00623 4.5e-112 ccpN K CBS domain
COEIJKGJ_00624 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COEIJKGJ_00625 4.5e-88 yaiI S Belongs to the UPF0178 family
COEIJKGJ_00626 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COEIJKGJ_00627 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COEIJKGJ_00628 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
COEIJKGJ_00629 1.5e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
COEIJKGJ_00630 5.3e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COEIJKGJ_00631 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
COEIJKGJ_00632 3.5e-12 yqfQ S YqfQ-like protein
COEIJKGJ_00633 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COEIJKGJ_00634 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
COEIJKGJ_00635 7.9e-36 yqfT S Protein of unknown function (DUF2624)
COEIJKGJ_00636 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
COEIJKGJ_00637 1.9e-77 zur P Belongs to the Fur family
COEIJKGJ_00638 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
COEIJKGJ_00639 4.3e-62 yqfX S membrane
COEIJKGJ_00640 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
COEIJKGJ_00641 5.2e-47 yqfZ M LysM domain
COEIJKGJ_00642 3.9e-131 yqgB S Protein of unknown function (DUF1189)
COEIJKGJ_00643 4e-73 yqgC S protein conserved in bacteria
COEIJKGJ_00644 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
COEIJKGJ_00645 2.5e-231 yqgE EGP Major facilitator superfamily
COEIJKGJ_00646 0.0 pbpA 3.4.16.4 M penicillin-binding protein
COEIJKGJ_00647 3.4e-150 pstS P Phosphate
COEIJKGJ_00648 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
COEIJKGJ_00649 4.4e-158 pstA P Phosphate transport system permease
COEIJKGJ_00650 3.2e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COEIJKGJ_00651 8.3e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COEIJKGJ_00652 2.1e-71 yqzC S YceG-like family
COEIJKGJ_00653 3.5e-50 yqzD
COEIJKGJ_00655 1.5e-41 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
COEIJKGJ_00656 4.1e-133 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
COEIJKGJ_00657 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COEIJKGJ_00658 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COEIJKGJ_00659 2.5e-09 yqgO
COEIJKGJ_00660 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
COEIJKGJ_00661 3.1e-33 yqgQ S Protein conserved in bacteria
COEIJKGJ_00662 5.2e-181 glcK 2.7.1.2 G Glucokinase
COEIJKGJ_00663 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
COEIJKGJ_00664 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
COEIJKGJ_00665 2.7e-199 yqgU
COEIJKGJ_00666 6.9e-50 yqgV S Thiamine-binding protein
COEIJKGJ_00667 8.9e-23 yqgW S Protein of unknown function (DUF2759)
COEIJKGJ_00668 9.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
COEIJKGJ_00669 1.8e-37 yqgY S Protein of unknown function (DUF2626)
COEIJKGJ_00670 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
COEIJKGJ_00672 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COEIJKGJ_00673 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
COEIJKGJ_00674 1.4e-173 corA P Mg2 transporter protein
COEIJKGJ_00677 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
COEIJKGJ_00678 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
COEIJKGJ_00679 6.8e-47 comGC U Required for transformation and DNA binding
COEIJKGJ_00680 6.3e-70 gspH NU protein transport across the cell outer membrane
COEIJKGJ_00681 2e-58 comGE
COEIJKGJ_00682 1.7e-34 comGF U Putative Competence protein ComGF
COEIJKGJ_00683 8.8e-44 S ComG operon protein 7
COEIJKGJ_00684 4.4e-25 yqzE S YqzE-like protein
COEIJKGJ_00685 7.3e-54 yqzG S Protein of unknown function (DUF3889)
COEIJKGJ_00686 2.8e-113 yqxM
COEIJKGJ_00687 2.5e-58 sipW 3.4.21.89 U Signal peptidase
COEIJKGJ_00688 1.9e-141 tasA S Cell division protein FtsN
COEIJKGJ_00689 1e-54 sinR K transcriptional
COEIJKGJ_00690 1.2e-24 sinI S Anti-repressor SinI
COEIJKGJ_00691 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
COEIJKGJ_00692 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
COEIJKGJ_00693 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
COEIJKGJ_00694 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
COEIJKGJ_00695 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
COEIJKGJ_00696 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
COEIJKGJ_00697 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
COEIJKGJ_00698 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
COEIJKGJ_00699 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
COEIJKGJ_00700 2.2e-61 yqhP
COEIJKGJ_00701 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
COEIJKGJ_00702 2.3e-93 yqhR S Conserved membrane protein YqhR
COEIJKGJ_00703 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
COEIJKGJ_00704 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
COEIJKGJ_00705 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COEIJKGJ_00706 7.9e-37 yqhV S Protein of unknown function (DUF2619)
COEIJKGJ_00707 1e-170 spoIIIAA S stage III sporulation protein AA
COEIJKGJ_00708 1.1e-84 spoIIIAB S Stage III sporulation protein
COEIJKGJ_00709 7.6e-29 spoIIIAC S stage III sporulation protein AC
COEIJKGJ_00710 2.3e-58 spoIIIAD S Stage III sporulation protein AD
COEIJKGJ_00711 2.9e-197 spoIIIAE S stage III sporulation protein AE
COEIJKGJ_00712 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
COEIJKGJ_00713 6.5e-109 spoIIIAG S stage III sporulation protein AG
COEIJKGJ_00714 9.9e-91 spoIIIAH S SpoIIIAH-like protein
COEIJKGJ_00715 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COEIJKGJ_00716 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
COEIJKGJ_00717 2.1e-67 yqhY S protein conserved in bacteria
COEIJKGJ_00718 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COEIJKGJ_00719 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COEIJKGJ_00720 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COEIJKGJ_00721 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COEIJKGJ_00722 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COEIJKGJ_00723 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COEIJKGJ_00724 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
COEIJKGJ_00725 1.7e-78 argR K Regulates arginine biosynthesis genes
COEIJKGJ_00726 0.0 recN L May be involved in recombinational repair of damaged DNA
COEIJKGJ_00727 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
COEIJKGJ_00728 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
COEIJKGJ_00730 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
COEIJKGJ_00731 5.9e-27
COEIJKGJ_00732 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
COEIJKGJ_00733 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COEIJKGJ_00734 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
COEIJKGJ_00735 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
COEIJKGJ_00736 8.8e-212 mmgC I acyl-CoA dehydrogenase
COEIJKGJ_00737 8.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
COEIJKGJ_00738 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
COEIJKGJ_00739 6.9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
COEIJKGJ_00740 4e-34 yqzF S Protein of unknown function (DUF2627)
COEIJKGJ_00741 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
COEIJKGJ_00742 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
COEIJKGJ_00743 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
COEIJKGJ_00744 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
COEIJKGJ_00745 2.8e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
COEIJKGJ_00746 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
COEIJKGJ_00747 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
COEIJKGJ_00748 5.4e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COEIJKGJ_00749 6.4e-151 bmrR K helix_turn_helix, mercury resistance
COEIJKGJ_00750 5.1e-207 norA EGP Major facilitator Superfamily
COEIJKGJ_00751 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
COEIJKGJ_00752 9.3e-77 yqiW S Belongs to the UPF0403 family
COEIJKGJ_00753 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
COEIJKGJ_00754 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
COEIJKGJ_00755 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
COEIJKGJ_00756 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
COEIJKGJ_00757 1.4e-98 yqjB S protein conserved in bacteria
COEIJKGJ_00759 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
COEIJKGJ_00760 3.8e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
COEIJKGJ_00761 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
COEIJKGJ_00762 2.6e-140 yqjF S Uncharacterized conserved protein (COG2071)
COEIJKGJ_00763 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COEIJKGJ_00764 4.5e-24 yqzJ
COEIJKGJ_00765 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COEIJKGJ_00766 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COEIJKGJ_00767 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COEIJKGJ_00768 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COEIJKGJ_00769 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COEIJKGJ_00770 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COEIJKGJ_00771 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
COEIJKGJ_00772 0.0 rocB E arginine degradation protein
COEIJKGJ_00773 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COEIJKGJ_00774 4.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
COEIJKGJ_00775 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_00776 9.3e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
COEIJKGJ_00777 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
COEIJKGJ_00778 4.7e-08 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COEIJKGJ_00779 1.1e-42 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COEIJKGJ_00781 6.1e-222 yqjV G Major Facilitator Superfamily
COEIJKGJ_00783 9.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COEIJKGJ_00784 2.2e-49 S YolD-like protein
COEIJKGJ_00785 1.8e-86 yqjY K acetyltransferase
COEIJKGJ_00786 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
COEIJKGJ_00787 7.5e-194 yqkA K GrpB protein
COEIJKGJ_00788 2.8e-54 yqkB S Belongs to the HesB IscA family
COEIJKGJ_00789 9.4e-39 yqkC S Protein of unknown function (DUF2552)
COEIJKGJ_00790 8.5e-173 yqkD S COG1073 Hydrolases of the alpha beta superfamily
COEIJKGJ_00791 3.1e-12 yqkE S Protein of unknown function (DUF3886)
COEIJKGJ_00792 4.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
COEIJKGJ_00794 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
COEIJKGJ_00795 1.4e-220 yqxK 3.6.4.12 L DNA helicase
COEIJKGJ_00796 4.5e-58 ansR K Transcriptional regulator
COEIJKGJ_00797 2.3e-184 ansA 3.5.1.1 EJ L-asparaginase
COEIJKGJ_00798 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
COEIJKGJ_00799 2.7e-234 mleN C Na H antiporter
COEIJKGJ_00800 5.5e-242 mleA 1.1.1.38 C malic enzyme
COEIJKGJ_00801 5.5e-30 yqkK
COEIJKGJ_00802 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
COEIJKGJ_00803 2.4e-80 fur P Belongs to the Fur family
COEIJKGJ_00804 3.7e-37 S Protein of unknown function (DUF4227)
COEIJKGJ_00805 2.6e-166 xerD L recombinase XerD
COEIJKGJ_00806 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
COEIJKGJ_00807 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
COEIJKGJ_00808 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
COEIJKGJ_00809 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
COEIJKGJ_00810 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
COEIJKGJ_00811 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COEIJKGJ_00812 7.4e-112 spoVAA S Stage V sporulation protein AA
COEIJKGJ_00813 1e-67 spoVAB S Stage V sporulation protein AB
COEIJKGJ_00814 2.3e-78 spoVAC S stage V sporulation protein AC
COEIJKGJ_00815 9e-192 spoVAD I Stage V sporulation protein AD
COEIJKGJ_00816 2.2e-57 spoVAEB S stage V sporulation protein
COEIJKGJ_00817 1.4e-110 spoVAEA S stage V sporulation protein
COEIJKGJ_00818 1.4e-273 spoVAF EG Stage V sporulation protein AF
COEIJKGJ_00819 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COEIJKGJ_00820 3.6e-149 ypuA S Secreted protein
COEIJKGJ_00821 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COEIJKGJ_00824 3.4e-13 S PAP2 superfamily
COEIJKGJ_00825 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
COEIJKGJ_00826 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
COEIJKGJ_00827 7.8e-55 ypuD
COEIJKGJ_00828 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COEIJKGJ_00829 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
COEIJKGJ_00830 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
COEIJKGJ_00831 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COEIJKGJ_00832 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEIJKGJ_00833 1.4e-92 ypuF S Domain of unknown function (DUF309)
COEIJKGJ_00834 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COEIJKGJ_00835 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COEIJKGJ_00836 7.6e-97 ypuI S Protein of unknown function (DUF3907)
COEIJKGJ_00837 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
COEIJKGJ_00838 3.5e-103 spmA S Spore maturation protein
COEIJKGJ_00839 1.9e-87 spmB S Spore maturation protein
COEIJKGJ_00840 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COEIJKGJ_00841 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
COEIJKGJ_00842 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
COEIJKGJ_00843 9.7e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
COEIJKGJ_00844 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_00845 0.0 resE 2.7.13.3 T Histidine kinase
COEIJKGJ_00846 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_00847 7.3e-195 rsiX
COEIJKGJ_00848 2.2e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
COEIJKGJ_00849 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEIJKGJ_00850 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COEIJKGJ_00851 4.7e-41 fer C Ferredoxin
COEIJKGJ_00852 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
COEIJKGJ_00853 3.2e-286 recQ 3.6.4.12 L DNA helicase
COEIJKGJ_00854 2.2e-100 ypbD S metal-dependent membrane protease
COEIJKGJ_00855 4.6e-81 ypbE M Lysin motif
COEIJKGJ_00856 2.8e-81 ypbF S Protein of unknown function (DUF2663)
COEIJKGJ_00857 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
COEIJKGJ_00858 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
COEIJKGJ_00859 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
COEIJKGJ_00860 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
COEIJKGJ_00861 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
COEIJKGJ_00862 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
COEIJKGJ_00863 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
COEIJKGJ_00864 9.2e-113 ypfA M Flagellar protein YcgR
COEIJKGJ_00865 1.8e-23 S Family of unknown function (DUF5359)
COEIJKGJ_00866 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COEIJKGJ_00867 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
COEIJKGJ_00868 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COEIJKGJ_00869 1e-07 S YpzI-like protein
COEIJKGJ_00870 1.3e-102 yphA
COEIJKGJ_00871 2.5e-161 seaA S YIEGIA protein
COEIJKGJ_00872 1.6e-28 ypzH
COEIJKGJ_00873 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COEIJKGJ_00874 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COEIJKGJ_00875 1.6e-18 yphE S Protein of unknown function (DUF2768)
COEIJKGJ_00876 5.4e-138 yphF
COEIJKGJ_00877 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
COEIJKGJ_00878 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COEIJKGJ_00879 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
COEIJKGJ_00880 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
COEIJKGJ_00881 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
COEIJKGJ_00882 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COEIJKGJ_00883 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COEIJKGJ_00884 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
COEIJKGJ_00885 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
COEIJKGJ_00886 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
COEIJKGJ_00887 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
COEIJKGJ_00888 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
COEIJKGJ_00889 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COEIJKGJ_00890 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COEIJKGJ_00891 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
COEIJKGJ_00892 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
COEIJKGJ_00893 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
COEIJKGJ_00894 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
COEIJKGJ_00895 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COEIJKGJ_00896 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
COEIJKGJ_00897 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
COEIJKGJ_00898 4.1e-234 S COG0457 FOG TPR repeat
COEIJKGJ_00899 1.1e-98 ypiB S Belongs to the UPF0302 family
COEIJKGJ_00900 4.2e-77 ypiF S Protein of unknown function (DUF2487)
COEIJKGJ_00901 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
COEIJKGJ_00902 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
COEIJKGJ_00903 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
COEIJKGJ_00904 7.6e-98 ypjA S membrane
COEIJKGJ_00905 1e-142 ypjB S sporulation protein
COEIJKGJ_00906 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
COEIJKGJ_00907 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
COEIJKGJ_00908 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COEIJKGJ_00909 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
COEIJKGJ_00910 1.7e-128 bshB1 S proteins, LmbE homologs
COEIJKGJ_00911 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
COEIJKGJ_00912 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COEIJKGJ_00913 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COEIJKGJ_00914 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
COEIJKGJ_00915 6.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
COEIJKGJ_00916 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
COEIJKGJ_00917 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COEIJKGJ_00918 1.9e-22 ypmA S Protein of unknown function (DUF4264)
COEIJKGJ_00919 4.9e-79 ypmB S protein conserved in bacteria
COEIJKGJ_00920 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
COEIJKGJ_00921 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
COEIJKGJ_00922 1.3e-128 dnaD L DNA replication protein DnaD
COEIJKGJ_00923 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COEIJKGJ_00924 1.8e-92 ypoC
COEIJKGJ_00925 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
COEIJKGJ_00926 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COEIJKGJ_00927 5.4e-186 yppC S Protein of unknown function (DUF2515)
COEIJKGJ_00930 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
COEIJKGJ_00932 6.6e-47 yppG S YppG-like protein
COEIJKGJ_00933 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
COEIJKGJ_00934 1.2e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
COEIJKGJ_00935 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
COEIJKGJ_00936 2.5e-236 yprB L RNase_H superfamily
COEIJKGJ_00937 8.2e-91 ypsA S Belongs to the UPF0398 family
COEIJKGJ_00938 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COEIJKGJ_00939 1.2e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COEIJKGJ_00941 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
COEIJKGJ_00942 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_00943 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
COEIJKGJ_00944 7.4e-186 ptxS K transcriptional
COEIJKGJ_00945 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
COEIJKGJ_00946 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
COEIJKGJ_00947 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
COEIJKGJ_00948 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
COEIJKGJ_00949 4.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COEIJKGJ_00950 3.8e-227 pbuX F xanthine
COEIJKGJ_00951 8.2e-207 bcsA Q Naringenin-chalcone synthase
COEIJKGJ_00952 7.4e-86 ypbQ S protein conserved in bacteria
COEIJKGJ_00954 0.0 ypbR S Dynamin family
COEIJKGJ_00955 8.5e-38 ypbS S Protein of unknown function (DUF2533)
COEIJKGJ_00956 2e-07
COEIJKGJ_00957 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
COEIJKGJ_00959 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
COEIJKGJ_00960 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
COEIJKGJ_00961 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
COEIJKGJ_00962 2.6e-27 ypeQ S Zinc-finger
COEIJKGJ_00963 1.8e-30 S Protein of unknown function (DUF2564)
COEIJKGJ_00964 3.8e-16 degR
COEIJKGJ_00965 7.9e-31 cspD K Cold-shock protein
COEIJKGJ_00966 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
COEIJKGJ_00967 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
COEIJKGJ_00968 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
COEIJKGJ_00969 5.4e-107 ypgQ S phosphohydrolase
COEIJKGJ_00970 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
COEIJKGJ_00971 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
COEIJKGJ_00972 1.7e-75 yphP S Belongs to the UPF0403 family
COEIJKGJ_00973 3.7e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
COEIJKGJ_00974 7.8e-114 ypjP S YpjP-like protein
COEIJKGJ_00975 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
COEIJKGJ_00976 1.5e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COEIJKGJ_00977 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COEIJKGJ_00978 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
COEIJKGJ_00979 4.2e-110 hlyIII S protein, Hemolysin III
COEIJKGJ_00980 1.6e-185 pspF K Transcriptional regulator
COEIJKGJ_00981 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
COEIJKGJ_00982 3.1e-40 ypmP S Protein of unknown function (DUF2535)
COEIJKGJ_00983 2.7e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
COEIJKGJ_00984 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
COEIJKGJ_00985 1.1e-98 ypmS S protein conserved in bacteria
COEIJKGJ_00986 5.5e-29 ypmT S Uncharacterized ympT
COEIJKGJ_00987 3.8e-222 mepA V MATE efflux family protein
COEIJKGJ_00988 1.6e-70 ypoP K transcriptional
COEIJKGJ_00989 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COEIJKGJ_00990 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COEIJKGJ_00991 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
COEIJKGJ_00992 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
COEIJKGJ_00993 2e-185 cgeB S Spore maturation protein
COEIJKGJ_00994 1.2e-65 cgeA
COEIJKGJ_00995 3.5e-38 cgeC
COEIJKGJ_00996 1e-256 cgeD M maturation of the outermost layer of the spore
COEIJKGJ_00997 8.3e-145 yiiD K acetyltransferase
COEIJKGJ_00999 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COEIJKGJ_01000 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
COEIJKGJ_01001 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
COEIJKGJ_01002 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
COEIJKGJ_01003 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
COEIJKGJ_01004 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
COEIJKGJ_01005 2.9e-47 yokU S YokU-like protein, putative antitoxin
COEIJKGJ_01006 1.4e-36 yozE S Belongs to the UPF0346 family
COEIJKGJ_01007 1.4e-124 yodN
COEIJKGJ_01009 2.8e-24 yozD S YozD-like protein
COEIJKGJ_01010 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
COEIJKGJ_01011 3.6e-54 yodL S YodL-like
COEIJKGJ_01012 5.3e-09
COEIJKGJ_01013 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
COEIJKGJ_01014 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
COEIJKGJ_01015 5.2e-24 yodI
COEIJKGJ_01016 1.7e-128 yodH Q Methyltransferase
COEIJKGJ_01017 1.6e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
COEIJKGJ_01018 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COEIJKGJ_01019 6.2e-28 S Protein of unknown function (DUF3311)
COEIJKGJ_01020 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
COEIJKGJ_01021 3.8e-113 mhqD S Carboxylesterase
COEIJKGJ_01022 4.8e-108 yodC C nitroreductase
COEIJKGJ_01023 1.7e-57 yodB K transcriptional
COEIJKGJ_01024 3.8e-66 yodA S tautomerase
COEIJKGJ_01025 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
COEIJKGJ_01026 3.4e-09
COEIJKGJ_01027 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
COEIJKGJ_01028 6.6e-162 rarD S -transporter
COEIJKGJ_01029 1.5e-43
COEIJKGJ_01030 2.2e-60 yojF S Protein of unknown function (DUF1806)
COEIJKGJ_01031 2.1e-125 yojG S deacetylase
COEIJKGJ_01032 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COEIJKGJ_01033 4.2e-245 norM V Multidrug efflux pump
COEIJKGJ_01035 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COEIJKGJ_01036 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
COEIJKGJ_01037 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
COEIJKGJ_01038 4.8e-90 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
COEIJKGJ_01039 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
COEIJKGJ_01040 0.0 yojO P Von Willebrand factor
COEIJKGJ_01041 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
COEIJKGJ_01042 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
COEIJKGJ_01043 8.6e-168 yocS S -transporter
COEIJKGJ_01044 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
COEIJKGJ_01045 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
COEIJKGJ_01046 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
COEIJKGJ_01047 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
COEIJKGJ_01048 2.7e-31 yozC
COEIJKGJ_01049 4.2e-56 yozO S Bacterial PH domain
COEIJKGJ_01050 1.9e-36 yocN
COEIJKGJ_01051 1.1e-40 yozN
COEIJKGJ_01052 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
COEIJKGJ_01053 6.6e-34
COEIJKGJ_01054 6.4e-54 yocL
COEIJKGJ_01055 3.3e-83 dksA T general stress protein
COEIJKGJ_01056 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COEIJKGJ_01057 0.0 recQ 3.6.4.12 L DNA helicase
COEIJKGJ_01058 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
COEIJKGJ_01059 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COEIJKGJ_01060 1.7e-196 desK 2.7.13.3 T Histidine kinase
COEIJKGJ_01061 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
COEIJKGJ_01062 1.5e-188 yocD 3.4.17.13 V peptidase S66
COEIJKGJ_01063 1.2e-93 yocC
COEIJKGJ_01064 1.3e-142
COEIJKGJ_01065 1.5e-92 yozB S membrane
COEIJKGJ_01066 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
COEIJKGJ_01067 1e-51 czrA K transcriptional
COEIJKGJ_01068 1.8e-90 yobW
COEIJKGJ_01069 6.2e-171 yobV K WYL domain
COEIJKGJ_01070 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
COEIJKGJ_01071 2.8e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
COEIJKGJ_01072 1.3e-97 yobS K Transcriptional regulator
COEIJKGJ_01073 5.3e-141 yobR 2.3.1.1 J FR47-like protein
COEIJKGJ_01074 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
COEIJKGJ_01075 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
COEIJKGJ_01076 0.0 yobO M Pectate lyase superfamily protein
COEIJKGJ_01077 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
COEIJKGJ_01078 9.1e-101 yokH G SMI1 / KNR4 family
COEIJKGJ_01079 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
COEIJKGJ_01080 2.8e-84 S SMI1-KNR4 cell-wall
COEIJKGJ_01082 2.9e-272 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
COEIJKGJ_01083 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
COEIJKGJ_01084 1.2e-63 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
COEIJKGJ_01085 2.7e-176 T PhoQ Sensor
COEIJKGJ_01087 1.7e-40
COEIJKGJ_01089 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
COEIJKGJ_01090 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
COEIJKGJ_01093 3.8e-165 bla 3.5.2.6 V beta-lactamase
COEIJKGJ_01094 4.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
COEIJKGJ_01095 1.8e-77 yoaW
COEIJKGJ_01096 1.5e-158 yijE EG EamA-like transporter family
COEIJKGJ_01097 8.6e-159 yoaU K LysR substrate binding domain
COEIJKGJ_01098 5.3e-147 yoaT S Protein of unknown function (DUF817)
COEIJKGJ_01099 4.4e-30 yozG K Transcriptional regulator
COEIJKGJ_01100 2.8e-74 yoaS S Protein of unknown function (DUF2975)
COEIJKGJ_01101 9.3e-172 yoaR V vancomycin resistance protein
COEIJKGJ_01102 7.3e-86
COEIJKGJ_01105 7.9e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
COEIJKGJ_01107 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
COEIJKGJ_01108 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
COEIJKGJ_01109 2.3e-111 yoaK S Membrane
COEIJKGJ_01110 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
COEIJKGJ_01111 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
COEIJKGJ_01112 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
COEIJKGJ_01113 1.5e-38 S Protein of unknown function (DUF4025)
COEIJKGJ_01114 2.2e-07
COEIJKGJ_01115 3.3e-90 purR K Transcriptional regulator
COEIJKGJ_01116 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
COEIJKGJ_01117 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
COEIJKGJ_01118 3e-172 iolT EGP Major facilitator Superfamily
COEIJKGJ_01119 6.6e-32 yoaF
COEIJKGJ_01120 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COEIJKGJ_01121 3.8e-99 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEIJKGJ_01122 1.7e-70 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEIJKGJ_01123 5.3e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
COEIJKGJ_01124 1.2e-233 yoaB EGP Major facilitator Superfamily
COEIJKGJ_01125 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
COEIJKGJ_01126 1.8e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
COEIJKGJ_01127 2.9e-94 V ABC-2 family transporter protein
COEIJKGJ_01128 3.8e-126 V ABC-2 family transporter protein
COEIJKGJ_01129 5.6e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
COEIJKGJ_01130 2.5e-130 yoxB
COEIJKGJ_01131 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
COEIJKGJ_01132 7.7e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_01133 2e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
COEIJKGJ_01134 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COEIJKGJ_01135 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COEIJKGJ_01136 3.9e-154 gltC K Transcriptional regulator
COEIJKGJ_01137 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
COEIJKGJ_01138 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
COEIJKGJ_01139 8e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
COEIJKGJ_01140 2.3e-156 gltR1 K Transcriptional regulator
COEIJKGJ_01141 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
COEIJKGJ_01142 3e-34 yoeD G Helix-turn-helix domain
COEIJKGJ_01143 2.2e-96 L Integrase
COEIJKGJ_01145 2.6e-97 yoeB S IseA DL-endopeptidase inhibitor
COEIJKGJ_01146 2.3e-246 yoeA V MATE efflux family protein
COEIJKGJ_01147 5.6e-191 yoxA 5.1.3.3 G Aldose 1-epimerase
COEIJKGJ_01148 1.4e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
COEIJKGJ_01149 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_01150 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_01151 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_01152 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
COEIJKGJ_01153 1.4e-92 M1-753 M FR47-like protein
COEIJKGJ_01154 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
COEIJKGJ_01155 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
COEIJKGJ_01156 3.9e-84 yuaE S DinB superfamily
COEIJKGJ_01157 7.4e-106 yuaD
COEIJKGJ_01158 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
COEIJKGJ_01159 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
COEIJKGJ_01160 2.7e-94 yuaC K Belongs to the GbsR family
COEIJKGJ_01161 2.2e-91 yuaB
COEIJKGJ_01162 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
COEIJKGJ_01163 1.6e-236 ktrB P Potassium
COEIJKGJ_01164 1e-38 yiaA S yiaA/B two helix domain
COEIJKGJ_01165 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COEIJKGJ_01166 2.4e-273 yubD P Major Facilitator Superfamily
COEIJKGJ_01167 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
COEIJKGJ_01169 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
COEIJKGJ_01170 1.3e-194 yubA S transporter activity
COEIJKGJ_01171 3.3e-183 ygjR S Oxidoreductase
COEIJKGJ_01172 6.7e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
COEIJKGJ_01173 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
COEIJKGJ_01174 5.1e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
COEIJKGJ_01175 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
COEIJKGJ_01176 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
COEIJKGJ_01177 7.3e-238 mcpA NT chemotaxis protein
COEIJKGJ_01178 4.7e-293 mcpA NT chemotaxis protein
COEIJKGJ_01179 2.4e-220 mcpA NT chemotaxis protein
COEIJKGJ_01180 3.2e-225 mcpA NT chemotaxis protein
COEIJKGJ_01181 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
COEIJKGJ_01182 2.3e-35
COEIJKGJ_01183 1.8e-71 yugU S Uncharacterised protein family UPF0047
COEIJKGJ_01184 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
COEIJKGJ_01185 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
COEIJKGJ_01186 1.4e-116 yugP S Zn-dependent protease
COEIJKGJ_01187 2.3e-38
COEIJKGJ_01188 1.1e-53 mstX S Membrane-integrating protein Mistic
COEIJKGJ_01189 2.2e-182 yugO P COG1226 Kef-type K transport systems
COEIJKGJ_01190 1.3e-72 yugN S YugN-like family
COEIJKGJ_01192 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
COEIJKGJ_01193 2.8e-229 yugK C Dehydrogenase
COEIJKGJ_01194 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
COEIJKGJ_01195 3.1e-34 yuzA S Domain of unknown function (DUF378)
COEIJKGJ_01196 1.5e-62 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
COEIJKGJ_01197 2.1e-199 yugH 2.6.1.1 E Aminotransferase
COEIJKGJ_01198 1.6e-85 alaR K Transcriptional regulator
COEIJKGJ_01199 4.9e-156 yugF I Hydrolase
COEIJKGJ_01200 1.6e-39 yugE S Domain of unknown function (DUF1871)
COEIJKGJ_01201 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
COEIJKGJ_01202 4.6e-233 T PhoQ Sensor
COEIJKGJ_01203 3.1e-68 kapB G Kinase associated protein B
COEIJKGJ_01204 1.9e-115 kapD L the KinA pathway to sporulation
COEIJKGJ_01206 3.8e-185 yuxJ EGP Major facilitator Superfamily
COEIJKGJ_01207 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
COEIJKGJ_01208 1.8e-74 yuxK S protein conserved in bacteria
COEIJKGJ_01209 6.3e-78 yufK S Family of unknown function (DUF5366)
COEIJKGJ_01210 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
COEIJKGJ_01211 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
COEIJKGJ_01212 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
COEIJKGJ_01213 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
COEIJKGJ_01214 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
COEIJKGJ_01215 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
COEIJKGJ_01216 1.3e-233 maeN C COG3493 Na citrate symporter
COEIJKGJ_01217 3.2e-14
COEIJKGJ_01218 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
COEIJKGJ_01219 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COEIJKGJ_01220 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COEIJKGJ_01221 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COEIJKGJ_01222 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COEIJKGJ_01223 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
COEIJKGJ_01224 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
COEIJKGJ_01225 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
COEIJKGJ_01226 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COEIJKGJ_01227 0.0 comP 2.7.13.3 T Histidine kinase
COEIJKGJ_01229 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
COEIJKGJ_01232 3.2e-22 yuzC
COEIJKGJ_01233 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
COEIJKGJ_01234 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COEIJKGJ_01235 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
COEIJKGJ_01236 7.9e-67 yueI S Protein of unknown function (DUF1694)
COEIJKGJ_01237 2.8e-38 yueH S YueH-like protein
COEIJKGJ_01238 2.1e-32 yueG S Spore germination protein gerPA/gerPF
COEIJKGJ_01239 1.9e-190 yueF S transporter activity
COEIJKGJ_01240 6.1e-72 S Protein of unknown function (DUF2283)
COEIJKGJ_01241 2.9e-24 S Protein of unknown function (DUF2642)
COEIJKGJ_01242 4.8e-96 yueE S phosphohydrolase
COEIJKGJ_01243 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_01244 6.6e-65 yueC S Family of unknown function (DUF5383)
COEIJKGJ_01245 0.0 esaA S type VII secretion protein EsaA
COEIJKGJ_01246 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
COEIJKGJ_01247 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
COEIJKGJ_01248 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
COEIJKGJ_01249 2.8e-45 esxA S Belongs to the WXG100 family
COEIJKGJ_01250 6.5e-229 yukF QT Transcriptional regulator
COEIJKGJ_01251 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
COEIJKGJ_01252 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
COEIJKGJ_01253 3.8e-36 mbtH S MbtH-like protein
COEIJKGJ_01254 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_01255 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
COEIJKGJ_01256 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
COEIJKGJ_01257 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
COEIJKGJ_01258 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_01259 1.3e-167 besA S Putative esterase
COEIJKGJ_01260 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
COEIJKGJ_01261 4.4e-93 bioY S Biotin biosynthesis protein
COEIJKGJ_01262 3.9e-211 yuiF S antiporter
COEIJKGJ_01263 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
COEIJKGJ_01264 1.2e-77 yuiD S protein conserved in bacteria
COEIJKGJ_01265 5.6e-118 yuiC S protein conserved in bacteria
COEIJKGJ_01266 8.4e-27 yuiB S Putative membrane protein
COEIJKGJ_01267 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
COEIJKGJ_01268 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
COEIJKGJ_01270 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COEIJKGJ_01271 1e-116 paiB K Putative FMN-binding domain
COEIJKGJ_01272 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEIJKGJ_01273 3.7e-63 erpA S Belongs to the HesB IscA family
COEIJKGJ_01274 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COEIJKGJ_01275 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COEIJKGJ_01276 3.2e-39 yuzB S Belongs to the UPF0349 family
COEIJKGJ_01277 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
COEIJKGJ_01278 3.5e-57 yuzD S protein conserved in bacteria
COEIJKGJ_01279 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
COEIJKGJ_01280 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
COEIJKGJ_01281 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COEIJKGJ_01282 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
COEIJKGJ_01283 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
COEIJKGJ_01284 2.9e-198 yutH S Spore coat protein
COEIJKGJ_01285 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
COEIJKGJ_01286 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COEIJKGJ_01287 8.6e-75 yutE S Protein of unknown function DUF86
COEIJKGJ_01288 9.7e-48 yutD S protein conserved in bacteria
COEIJKGJ_01289 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
COEIJKGJ_01290 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
COEIJKGJ_01291 3.8e-195 lytH M Peptidase, M23
COEIJKGJ_01292 4.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
COEIJKGJ_01293 5.3e-47 yunC S Domain of unknown function (DUF1805)
COEIJKGJ_01294 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
COEIJKGJ_01295 1e-140 yunE S membrane transporter protein
COEIJKGJ_01296 7.3e-171 yunF S Protein of unknown function DUF72
COEIJKGJ_01297 6.7e-62 yunG
COEIJKGJ_01298 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
COEIJKGJ_01299 3.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
COEIJKGJ_01300 2.1e-236 pbuX F Permease family
COEIJKGJ_01301 1.3e-222 pbuX F xanthine
COEIJKGJ_01302 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
COEIJKGJ_01303 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
COEIJKGJ_01304 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
COEIJKGJ_01305 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
COEIJKGJ_01306 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
COEIJKGJ_01307 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
COEIJKGJ_01308 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
COEIJKGJ_01310 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
COEIJKGJ_01311 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
COEIJKGJ_01312 2.4e-169 bsn L Ribonuclease
COEIJKGJ_01313 1.2e-205 msmX P Belongs to the ABC transporter superfamily
COEIJKGJ_01314 1.1e-135 yurK K UTRA
COEIJKGJ_01315 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
COEIJKGJ_01316 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
COEIJKGJ_01317 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
COEIJKGJ_01318 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
COEIJKGJ_01319 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
COEIJKGJ_01320 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
COEIJKGJ_01321 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
COEIJKGJ_01323 1e-41
COEIJKGJ_01324 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COEIJKGJ_01325 3.5e-271 sufB O FeS cluster assembly
COEIJKGJ_01326 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
COEIJKGJ_01327 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COEIJKGJ_01328 9.1e-245 sufD O assembly protein SufD
COEIJKGJ_01329 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
COEIJKGJ_01330 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COEIJKGJ_01331 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
COEIJKGJ_01332 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
COEIJKGJ_01333 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COEIJKGJ_01334 2.4e-56 yusD S SCP-2 sterol transfer family
COEIJKGJ_01335 5.6e-55 traF CO Thioredoxin
COEIJKGJ_01336 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
COEIJKGJ_01337 1.1e-39 yusG S Protein of unknown function (DUF2553)
COEIJKGJ_01338 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
COEIJKGJ_01339 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
COEIJKGJ_01340 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
COEIJKGJ_01341 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
COEIJKGJ_01342 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
COEIJKGJ_01343 8.1e-09 S YuzL-like protein
COEIJKGJ_01344 7.1e-164 fadM E Proline dehydrogenase
COEIJKGJ_01345 5.1e-40
COEIJKGJ_01346 5.4e-53 yusN M Coat F domain
COEIJKGJ_01347 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
COEIJKGJ_01348 3.2e-292 yusP P Major facilitator superfamily
COEIJKGJ_01349 2.7e-64 yusQ S Tautomerase enzyme
COEIJKGJ_01350 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_01351 5.7e-158 yusT K LysR substrate binding domain
COEIJKGJ_01352 3.8e-47 yusU S Protein of unknown function (DUF2573)
COEIJKGJ_01353 1e-153 yusV 3.6.3.34 HP ABC transporter
COEIJKGJ_01354 2.5e-66 S YusW-like protein
COEIJKGJ_01355 1.9e-301 pepF2 E COG1164 Oligoendopeptidase F
COEIJKGJ_01356 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_01357 1.2e-79 dps P Ferritin-like domain
COEIJKGJ_01358 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COEIJKGJ_01359 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_01360 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
COEIJKGJ_01361 4.3e-158 yuxN K Transcriptional regulator
COEIJKGJ_01362 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COEIJKGJ_01363 2.3e-24 S Protein of unknown function (DUF3970)
COEIJKGJ_01364 1.4e-246 gerAA EG Spore germination protein
COEIJKGJ_01365 9.1e-198 gerAB E Spore germination protein
COEIJKGJ_01366 3.3e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
COEIJKGJ_01367 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COEIJKGJ_01368 3.5e-186 vraS 2.7.13.3 T Histidine kinase
COEIJKGJ_01369 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
COEIJKGJ_01370 2.3e-127 liaG S Putative adhesin
COEIJKGJ_01371 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
COEIJKGJ_01372 5.6e-62 liaI S membrane
COEIJKGJ_01373 1.4e-226 yvqJ EGP Major facilitator Superfamily
COEIJKGJ_01374 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
COEIJKGJ_01375 1.1e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
COEIJKGJ_01376 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_01377 1.9e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
COEIJKGJ_01378 2.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_01379 2.9e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
COEIJKGJ_01380 0.0 T PhoQ Sensor
COEIJKGJ_01381 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_01382 3.6e-22
COEIJKGJ_01383 9.5e-98 yvrI K RNA polymerase
COEIJKGJ_01384 2.4e-19 S YvrJ protein family
COEIJKGJ_01385 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
COEIJKGJ_01386 3.8e-64 yvrL S Regulatory protein YrvL
COEIJKGJ_01387 3.4e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
COEIJKGJ_01388 2.1e-123 macB V ABC transporter, ATP-binding protein
COEIJKGJ_01389 2.6e-174 M Efflux transporter rnd family, mfp subunit
COEIJKGJ_01390 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
COEIJKGJ_01391 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_01392 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_01393 7.6e-177 fhuD P ABC transporter
COEIJKGJ_01395 4.9e-236 yvsH E Arginine ornithine antiporter
COEIJKGJ_01396 6.5e-16 S Small spore protein J (Spore_SspJ)
COEIJKGJ_01397 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
COEIJKGJ_01398 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
COEIJKGJ_01399 1.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
COEIJKGJ_01400 4.9e-137 modA P COG0725 ABC-type molybdate transport system, periplasmic component
COEIJKGJ_01401 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
COEIJKGJ_01402 2.2e-156 yvgN S reductase
COEIJKGJ_01403 2.1e-85 yvgO
COEIJKGJ_01404 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
COEIJKGJ_01405 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
COEIJKGJ_01406 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
COEIJKGJ_01407 0.0 helD 3.6.4.12 L DNA helicase
COEIJKGJ_01409 2.7e-106 yvgT S membrane
COEIJKGJ_01410 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
COEIJKGJ_01411 1.6e-104 bdbD O Thioredoxin
COEIJKGJ_01412 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
COEIJKGJ_01413 0.0 copA 3.6.3.54 P P-type ATPase
COEIJKGJ_01414 1.5e-29 copZ P Copper resistance protein CopZ
COEIJKGJ_01415 2.2e-48 csoR S transcriptional
COEIJKGJ_01416 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
COEIJKGJ_01417 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COEIJKGJ_01418 0.0 yvaC S Fusaric acid resistance protein-like
COEIJKGJ_01419 1.3e-72 yvaD S Family of unknown function (DUF5360)
COEIJKGJ_01420 6.3e-55 yvaE P Small Multidrug Resistance protein
COEIJKGJ_01421 4.1e-101 K Bacterial regulatory proteins, tetR family
COEIJKGJ_01422 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_01424 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
COEIJKGJ_01425 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COEIJKGJ_01426 5.6e-143 est 3.1.1.1 S Carboxylesterase
COEIJKGJ_01427 2.4e-23 secG U Preprotein translocase subunit SecG
COEIJKGJ_01428 3.7e-153 yvaM S Serine aminopeptidase, S33
COEIJKGJ_01429 7.5e-36 yvzC K Transcriptional
COEIJKGJ_01430 2.2e-54 yodB K transcriptional
COEIJKGJ_01431 1.1e-213 NT chemotaxis protein
COEIJKGJ_01432 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
COEIJKGJ_01433 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COEIJKGJ_01434 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
COEIJKGJ_01435 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
COEIJKGJ_01436 3.3e-60 yvbF K Belongs to the GbsR family
COEIJKGJ_01437 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
COEIJKGJ_01438 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COEIJKGJ_01439 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
COEIJKGJ_01440 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
COEIJKGJ_01441 3.5e-97 yvbF K Belongs to the GbsR family
COEIJKGJ_01442 2.7e-101 yvbG U UPF0056 membrane protein
COEIJKGJ_01443 8.6e-113 yvbH S YvbH-like oligomerisation region
COEIJKGJ_01444 1.3e-120 exoY M Membrane
COEIJKGJ_01445 0.0 tcaA S response to antibiotic
COEIJKGJ_01446 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
COEIJKGJ_01447 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COEIJKGJ_01448 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
COEIJKGJ_01449 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COEIJKGJ_01450 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COEIJKGJ_01451 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COEIJKGJ_01452 2.6e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
COEIJKGJ_01453 1.6e-252 araE EGP Major facilitator Superfamily
COEIJKGJ_01454 5.5e-203 araR K transcriptional
COEIJKGJ_01455 4.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COEIJKGJ_01456 5.1e-159 yvbU K Transcriptional regulator
COEIJKGJ_01457 7.2e-156 yvbV EG EamA-like transporter family
COEIJKGJ_01458 3.7e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
COEIJKGJ_01459 2.6e-194 yvbX S Glycosyl hydrolase
COEIJKGJ_01460 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
COEIJKGJ_01461 1.7e-273 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
COEIJKGJ_01462 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
COEIJKGJ_01463 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COEIJKGJ_01464 1.6e-194 desK 2.7.13.3 T Histidine kinase
COEIJKGJ_01465 6.9e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
COEIJKGJ_01466 1.7e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
COEIJKGJ_01467 6.4e-156 rsbQ S Alpha/beta hydrolase family
COEIJKGJ_01468 3.2e-196 rsbU 3.1.3.3 T response regulator
COEIJKGJ_01469 2.3e-248 galA 3.2.1.89 G arabinogalactan
COEIJKGJ_01470 0.0 lacA 3.2.1.23 G beta-galactosidase
COEIJKGJ_01471 7.2e-150 ganQ P transport
COEIJKGJ_01472 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
COEIJKGJ_01473 4.4e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
COEIJKGJ_01474 1.8e-184 lacR K Transcriptional regulator
COEIJKGJ_01475 1e-112 yvfI K COG2186 Transcriptional regulators
COEIJKGJ_01476 2.6e-308 yvfH C L-lactate permease
COEIJKGJ_01477 1.2e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
COEIJKGJ_01478 1e-31 yvfG S YvfG protein
COEIJKGJ_01479 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
COEIJKGJ_01480 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
COEIJKGJ_01481 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
COEIJKGJ_01482 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
COEIJKGJ_01483 1.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COEIJKGJ_01484 2.7e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
COEIJKGJ_01485 1.2e-202 epsI GM pyruvyl transferase
COEIJKGJ_01486 9.8e-194 epsH GT2 S Glycosyltransferase like family 2
COEIJKGJ_01487 7e-206 epsG S EpsG family
COEIJKGJ_01488 8.4e-218 epsF GT4 M Glycosyl transferases group 1
COEIJKGJ_01489 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COEIJKGJ_01490 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
COEIJKGJ_01491 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
COEIJKGJ_01492 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
COEIJKGJ_01493 4e-122 ywqC M biosynthesis protein
COEIJKGJ_01494 1.4e-75 slr K transcriptional
COEIJKGJ_01495 1.6e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
COEIJKGJ_01497 5.1e-92 padC Q Phenolic acid decarboxylase
COEIJKGJ_01498 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
COEIJKGJ_01499 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
COEIJKGJ_01500 3.2e-261 pbpE V Beta-lactamase
COEIJKGJ_01501 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
COEIJKGJ_01502 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
COEIJKGJ_01503 1.8e-295 yveA E amino acid
COEIJKGJ_01504 2.6e-106 yvdT K Transcriptional regulator
COEIJKGJ_01505 1.9e-50 ykkC P Small Multidrug Resistance protein
COEIJKGJ_01506 4.1e-50 sugE P Small Multidrug Resistance protein
COEIJKGJ_01507 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
COEIJKGJ_01508 1.1e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
COEIJKGJ_01509 2.8e-182 S Patatin-like phospholipase
COEIJKGJ_01511 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COEIJKGJ_01512 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
COEIJKGJ_01513 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
COEIJKGJ_01514 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
COEIJKGJ_01515 5e-154 malA S Protein of unknown function (DUF1189)
COEIJKGJ_01516 3.9e-148 malD P transport
COEIJKGJ_01517 5.9e-244 malC P COG1175 ABC-type sugar transport systems, permease components
COEIJKGJ_01518 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
COEIJKGJ_01519 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
COEIJKGJ_01520 3.6e-174 yvdE K Transcriptional regulator
COEIJKGJ_01521 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
COEIJKGJ_01522 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
COEIJKGJ_01523 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
COEIJKGJ_01524 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
COEIJKGJ_01525 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COEIJKGJ_01526 0.0 yxdM V ABC transporter (permease)
COEIJKGJ_01527 5.6e-141 yvcR V ABC transporter, ATP-binding protein
COEIJKGJ_01528 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
COEIJKGJ_01529 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_01530 1.8e-33
COEIJKGJ_01531 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
COEIJKGJ_01532 1.6e-36 crh G Phosphocarrier protein Chr
COEIJKGJ_01533 1.4e-170 whiA K May be required for sporulation
COEIJKGJ_01534 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COEIJKGJ_01535 5.7e-166 rapZ S Displays ATPase and GTPase activities
COEIJKGJ_01536 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
COEIJKGJ_01537 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COEIJKGJ_01538 1.1e-97 usp CBM50 M protein conserved in bacteria
COEIJKGJ_01539 4.5e-277 S COG0457 FOG TPR repeat
COEIJKGJ_01540 0.0 msbA2 3.6.3.44 V ABC transporter
COEIJKGJ_01542 0.0
COEIJKGJ_01543 1.9e-74
COEIJKGJ_01544 7.6e-65
COEIJKGJ_01545 2.6e-112 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
COEIJKGJ_01546 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
COEIJKGJ_01547 5.8e-132 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
COEIJKGJ_01548 7.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COEIJKGJ_01549 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
COEIJKGJ_01550 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
COEIJKGJ_01551 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
COEIJKGJ_01552 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
COEIJKGJ_01553 3.8e-139 yvpB NU protein conserved in bacteria
COEIJKGJ_01554 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
COEIJKGJ_01555 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
COEIJKGJ_01556 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
COEIJKGJ_01557 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
COEIJKGJ_01558 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COEIJKGJ_01559 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COEIJKGJ_01560 3.3e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
COEIJKGJ_01561 9.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COEIJKGJ_01562 8.9e-133 yvoA K transcriptional
COEIJKGJ_01563 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
COEIJKGJ_01564 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
COEIJKGJ_01565 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
COEIJKGJ_01566 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
COEIJKGJ_01567 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
COEIJKGJ_01568 2.7e-203 yvmA EGP Major facilitator Superfamily
COEIJKGJ_01569 1.2e-50 yvlD S Membrane
COEIJKGJ_01570 2.6e-26 pspB KT PspC domain
COEIJKGJ_01571 3.4e-168 yvlB S Putative adhesin
COEIJKGJ_01572 8e-49 yvlA
COEIJKGJ_01573 6.7e-34 yvkN
COEIJKGJ_01574 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
COEIJKGJ_01575 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COEIJKGJ_01576 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COEIJKGJ_01577 1.2e-30 csbA S protein conserved in bacteria
COEIJKGJ_01578 0.0 yvkC 2.7.9.2 GT Phosphotransferase
COEIJKGJ_01579 7e-101 yvkB K Transcriptional regulator
COEIJKGJ_01580 7.9e-228 yvkA EGP Major facilitator Superfamily
COEIJKGJ_01581 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COEIJKGJ_01582 5.3e-56 swrA S Swarming motility protein
COEIJKGJ_01583 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
COEIJKGJ_01584 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
COEIJKGJ_01585 1.6e-123 ftsE D cell division ATP-binding protein FtsE
COEIJKGJ_01586 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
COEIJKGJ_01587 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
COEIJKGJ_01588 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COEIJKGJ_01589 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COEIJKGJ_01590 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COEIJKGJ_01591 5.4e-65
COEIJKGJ_01592 1.9e-08 fliT S bacterial-type flagellum organization
COEIJKGJ_01593 2.9e-69 fliS N flagellar protein FliS
COEIJKGJ_01594 1.1e-265 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
COEIJKGJ_01595 6.1e-57 flaG N flagellar protein FlaG
COEIJKGJ_01596 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
COEIJKGJ_01597 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
COEIJKGJ_01598 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
COEIJKGJ_01599 2.6e-50 yviE
COEIJKGJ_01600 1.1e-156 flgL N Belongs to the bacterial flagellin family
COEIJKGJ_01601 1.2e-264 flgK N flagellar hook-associated protein
COEIJKGJ_01602 2.4e-78 flgN NOU FlgN protein
COEIJKGJ_01603 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
COEIJKGJ_01604 7e-74 yvyF S flagellar protein
COEIJKGJ_01605 2.7e-129 comFC S Phosphoribosyl transferase domain
COEIJKGJ_01606 5.7e-46 comFB S Late competence development protein ComFB
COEIJKGJ_01607 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
COEIJKGJ_01608 7.3e-155 degV S protein conserved in bacteria
COEIJKGJ_01609 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COEIJKGJ_01610 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
COEIJKGJ_01611 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
COEIJKGJ_01612 6e-163 yvhJ K Transcriptional regulator
COEIJKGJ_01613 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
COEIJKGJ_01614 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
COEIJKGJ_01615 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
COEIJKGJ_01616 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
COEIJKGJ_01617 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
COEIJKGJ_01618 4.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COEIJKGJ_01619 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
COEIJKGJ_01620 5.3e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COEIJKGJ_01621 7.8e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
COEIJKGJ_01622 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COEIJKGJ_01623 0.0 lytB 3.5.1.28 D Stage II sporulation protein
COEIJKGJ_01624 6e-38
COEIJKGJ_01625 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
COEIJKGJ_01626 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COEIJKGJ_01627 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COEIJKGJ_01628 6.5e-57
COEIJKGJ_01629 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COEIJKGJ_01630 7.5e-93 ggaA M Glycosyltransferase like family 2
COEIJKGJ_01631 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
COEIJKGJ_01632 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COEIJKGJ_01633 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COEIJKGJ_01634 9.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
COEIJKGJ_01635 4.1e-150 tagG GM Transport permease protein
COEIJKGJ_01636 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
COEIJKGJ_01637 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
COEIJKGJ_01638 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
COEIJKGJ_01639 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COEIJKGJ_01640 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
COEIJKGJ_01641 3.5e-260
COEIJKGJ_01642 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
COEIJKGJ_01643 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
COEIJKGJ_01644 1.2e-261 gerBA EG Spore germination protein
COEIJKGJ_01645 1.5e-192 gerBB E Spore germination protein
COEIJKGJ_01646 7.1e-206 gerAC S Spore germination protein
COEIJKGJ_01647 1.9e-248 ywtG EGP Major facilitator Superfamily
COEIJKGJ_01648 8.4e-171 ywtF K Transcriptional regulator
COEIJKGJ_01649 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
COEIJKGJ_01650 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
COEIJKGJ_01651 3.6e-21 ywtC
COEIJKGJ_01652 1.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
COEIJKGJ_01653 8.6e-70 pgsC S biosynthesis protein
COEIJKGJ_01654 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
COEIJKGJ_01655 9.3e-178 rbsR K transcriptional
COEIJKGJ_01656 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COEIJKGJ_01657 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
COEIJKGJ_01658 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
COEIJKGJ_01659 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
COEIJKGJ_01660 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
COEIJKGJ_01661 8.7e-93 batE T Sh3 type 3 domain protein
COEIJKGJ_01662 8e-48 ywsA S Protein of unknown function (DUF3892)
COEIJKGJ_01663 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
COEIJKGJ_01664 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
COEIJKGJ_01665 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
COEIJKGJ_01666 1.1e-169 alsR K LysR substrate binding domain
COEIJKGJ_01667 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
COEIJKGJ_01668 7.5e-126 ywrJ
COEIJKGJ_01669 2.9e-130 cotB
COEIJKGJ_01670 3.5e-210 cotH M Spore Coat
COEIJKGJ_01671 3.7e-12
COEIJKGJ_01672 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
COEIJKGJ_01673 1.4e-53 S Domain of unknown function (DUF4181)
COEIJKGJ_01674 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
COEIJKGJ_01675 8e-82 ywrC K Transcriptional regulator
COEIJKGJ_01676 1.2e-103 ywrB P Chromate transporter
COEIJKGJ_01677 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
COEIJKGJ_01679 1.1e-100 ywqN S NAD(P)H-dependent
COEIJKGJ_01680 1.4e-161 K Transcriptional regulator
COEIJKGJ_01681 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
COEIJKGJ_01682 3.9e-25
COEIJKGJ_01683 1.9e-82 ywqJ S Pre-toxin TG
COEIJKGJ_01684 5.2e-17
COEIJKGJ_01685 7.9e-43
COEIJKGJ_01686 9.7e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
COEIJKGJ_01687 8.6e-38 ywqI S Family of unknown function (DUF5344)
COEIJKGJ_01688 9.7e-23 S Domain of unknown function (DUF5082)
COEIJKGJ_01689 1.4e-152 ywqG S Domain of unknown function (DUF1963)
COEIJKGJ_01690 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
COEIJKGJ_01691 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
COEIJKGJ_01692 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
COEIJKGJ_01693 2e-116 ywqC M biosynthesis protein
COEIJKGJ_01694 1.2e-17
COEIJKGJ_01695 1.4e-308 ywqB S SWIM zinc finger
COEIJKGJ_01696 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
COEIJKGJ_01697 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
COEIJKGJ_01698 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
COEIJKGJ_01699 3.7e-57 ssbB L Single-stranded DNA-binding protein
COEIJKGJ_01700 3.8e-66 ywpG
COEIJKGJ_01701 1.1e-66 ywpF S YwpF-like protein
COEIJKGJ_01702 1.2e-49 srtA 3.4.22.70 M Sortase family
COEIJKGJ_01703 7e-153 ywpD T Histidine kinase
COEIJKGJ_01704 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COEIJKGJ_01705 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COEIJKGJ_01706 8.8e-198 S aspartate phosphatase
COEIJKGJ_01707 3.7e-140 flhP N flagellar basal body
COEIJKGJ_01708 9.9e-125 flhO N flagellar basal body
COEIJKGJ_01709 3.5e-180 mbl D Rod shape-determining protein
COEIJKGJ_01710 3e-44 spoIIID K Stage III sporulation protein D
COEIJKGJ_01711 2.1e-70 ywoH K COG1846 Transcriptional regulators
COEIJKGJ_01712 3.9e-210 ywoG EGP Major facilitator Superfamily
COEIJKGJ_01713 2.8e-231 ywoF P Right handed beta helix region
COEIJKGJ_01714 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
COEIJKGJ_01715 9.8e-242 ywoD EGP Major facilitator superfamily
COEIJKGJ_01716 4e-104 phzA Q Isochorismatase family
COEIJKGJ_01717 2.2e-76
COEIJKGJ_01718 2.5e-225 amt P Ammonium transporter
COEIJKGJ_01719 1.6e-58 nrgB K Belongs to the P(II) protein family
COEIJKGJ_01720 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
COEIJKGJ_01721 3e-72 ywnJ S VanZ like family
COEIJKGJ_01722 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
COEIJKGJ_01723 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
COEIJKGJ_01724 8.9e-10 ywnC S Family of unknown function (DUF5362)
COEIJKGJ_01725 2.2e-70 ywnF S Family of unknown function (DUF5392)
COEIJKGJ_01726 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COEIJKGJ_01727 5e-142 mta K transcriptional
COEIJKGJ_01728 2.6e-59 ywnC S Family of unknown function (DUF5362)
COEIJKGJ_01729 1.6e-114 ywnB S NAD(P)H-binding
COEIJKGJ_01730 1.7e-64 ywnA K Transcriptional regulator
COEIJKGJ_01731 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
COEIJKGJ_01732 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
COEIJKGJ_01733 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
COEIJKGJ_01735 3.8e-11 csbD K CsbD-like
COEIJKGJ_01736 3e-84 ywmF S Peptidase M50
COEIJKGJ_01737 1.3e-103 S response regulator aspartate phosphatase
COEIJKGJ_01738 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
COEIJKGJ_01739 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
COEIJKGJ_01741 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
COEIJKGJ_01742 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
COEIJKGJ_01743 1e-174 spoIID D Stage II sporulation protein D
COEIJKGJ_01744 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COEIJKGJ_01745 2.8e-134 ywmB S TATA-box binding
COEIJKGJ_01746 1.3e-32 ywzB S membrane
COEIJKGJ_01747 1.3e-60 ywmA
COEIJKGJ_01748 1.4e-13 ywmA
COEIJKGJ_01749 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COEIJKGJ_01750 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COEIJKGJ_01751 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COEIJKGJ_01752 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COEIJKGJ_01753 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COEIJKGJ_01754 6.4e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COEIJKGJ_01755 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COEIJKGJ_01756 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
COEIJKGJ_01757 2.5e-62 atpI S ATP synthase
COEIJKGJ_01758 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COEIJKGJ_01759 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COEIJKGJ_01760 7.2e-95 ywlG S Belongs to the UPF0340 family
COEIJKGJ_01761 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
COEIJKGJ_01762 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COEIJKGJ_01763 1.7e-91 mntP P Probably functions as a manganese efflux pump
COEIJKGJ_01764 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COEIJKGJ_01765 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
COEIJKGJ_01766 6.1e-112 spoIIR S stage II sporulation protein R
COEIJKGJ_01767 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
COEIJKGJ_01769 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COEIJKGJ_01770 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COEIJKGJ_01771 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COEIJKGJ_01772 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
COEIJKGJ_01773 8.6e-160 ywkB S Membrane transport protein
COEIJKGJ_01774 0.0 sfcA 1.1.1.38 C malic enzyme
COEIJKGJ_01775 1.6e-103 tdk 2.7.1.21 F thymidine kinase
COEIJKGJ_01776 1.1e-32 rpmE J Binds the 23S rRNA
COEIJKGJ_01777 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COEIJKGJ_01778 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
COEIJKGJ_01779 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COEIJKGJ_01780 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COEIJKGJ_01781 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
COEIJKGJ_01782 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
COEIJKGJ_01783 5.1e-90 ywjG S Domain of unknown function (DUF2529)
COEIJKGJ_01784 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COEIJKGJ_01785 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COEIJKGJ_01786 1.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
COEIJKGJ_01787 0.0 fadF C COG0247 Fe-S oxidoreductase
COEIJKGJ_01788 1.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
COEIJKGJ_01789 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
COEIJKGJ_01790 2.7e-42 ywjC
COEIJKGJ_01791 4.8e-96 ywjB H RibD C-terminal domain
COEIJKGJ_01792 0.0 ywjA V ABC transporter
COEIJKGJ_01793 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COEIJKGJ_01794 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
COEIJKGJ_01795 1.1e-93 narJ 1.7.5.1 C nitrate reductase
COEIJKGJ_01796 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
COEIJKGJ_01797 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COEIJKGJ_01798 7e-86 arfM T cyclic nucleotide binding
COEIJKGJ_01799 1.7e-139 ywiC S YwiC-like protein
COEIJKGJ_01800 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
COEIJKGJ_01801 2.3e-213 narK P COG2223 Nitrate nitrite transporter
COEIJKGJ_01802 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COEIJKGJ_01803 4.7e-73 ywiB S protein conserved in bacteria
COEIJKGJ_01804 1e-07 S Bacteriocin subtilosin A
COEIJKGJ_01805 4.9e-270 C Fe-S oxidoreductases
COEIJKGJ_01807 3.3e-132 cbiO V ABC transporter
COEIJKGJ_01808 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
COEIJKGJ_01809 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
COEIJKGJ_01810 1.6e-249 L Peptidase, M16
COEIJKGJ_01812 4.7e-244 ywhL CO amine dehydrogenase activity
COEIJKGJ_01813 3.2e-192 ywhK CO amine dehydrogenase activity
COEIJKGJ_01814 8.9e-79 S aspartate phosphatase
COEIJKGJ_01816 3.7e-28 ywhH S Aminoacyl-tRNA editing domain
COEIJKGJ_01817 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
COEIJKGJ_01818 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
COEIJKGJ_01819 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COEIJKGJ_01820 3.6e-49
COEIJKGJ_01821 5.2e-95 ywhD S YwhD family
COEIJKGJ_01822 5.1e-119 ywhC S Peptidase family M50
COEIJKGJ_01823 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
COEIJKGJ_01824 9.5e-71 ywhA K Transcriptional regulator
COEIJKGJ_01825 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COEIJKGJ_01827 9.8e-237 mmr U Major Facilitator Superfamily
COEIJKGJ_01828 6.2e-79 yffB K Transcriptional regulator
COEIJKGJ_01829 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
COEIJKGJ_01830 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
COEIJKGJ_01831 3.1e-36 ywzC S Belongs to the UPF0741 family
COEIJKGJ_01832 5.1e-110 rsfA_1
COEIJKGJ_01833 1.6e-155 ywfM EG EamA-like transporter family
COEIJKGJ_01834 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
COEIJKGJ_01835 1.1e-156 cysL K Transcriptional regulator
COEIJKGJ_01836 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
COEIJKGJ_01837 1.1e-146 ywfI C May function as heme-dependent peroxidase
COEIJKGJ_01838 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
COEIJKGJ_01839 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
COEIJKGJ_01840 1.9e-209 bacE EGP Major facilitator Superfamily
COEIJKGJ_01841 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
COEIJKGJ_01842 2.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_01843 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
COEIJKGJ_01844 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
COEIJKGJ_01845 6e-206 ywfA EGP Major facilitator Superfamily
COEIJKGJ_01846 4.8e-249 lysP E amino acid
COEIJKGJ_01847 0.0 rocB E arginine degradation protein
COEIJKGJ_01848 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
COEIJKGJ_01849 8.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
COEIJKGJ_01850 3.4e-77
COEIJKGJ_01851 1.3e-86 spsL 5.1.3.13 M Spore Coat
COEIJKGJ_01852 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
COEIJKGJ_01853 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
COEIJKGJ_01854 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
COEIJKGJ_01855 1.5e-183 spsG M Spore Coat
COEIJKGJ_01856 1e-128 spsF M Spore Coat
COEIJKGJ_01857 6e-213 spsE 2.5.1.56 M acid synthase
COEIJKGJ_01858 1.7e-162 spsD 2.3.1.210 K Spore Coat
COEIJKGJ_01859 1.1e-222 spsC E Belongs to the DegT DnrJ EryC1 family
COEIJKGJ_01860 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
COEIJKGJ_01861 4.5e-143 spsA M Spore Coat
COEIJKGJ_01862 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
COEIJKGJ_01863 4.3e-59 ywdK S small membrane protein
COEIJKGJ_01864 3.7e-238 ywdJ F Xanthine uracil
COEIJKGJ_01865 6.6e-48 ywdI S Family of unknown function (DUF5327)
COEIJKGJ_01866 3e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
COEIJKGJ_01867 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COEIJKGJ_01868 1.6e-151 ywdF GT2,GT4 S Glycosyltransferase like family 2
COEIJKGJ_01869 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COEIJKGJ_01870 2e-28 ywdA
COEIJKGJ_01871 1.4e-283 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
COEIJKGJ_01872 1.8e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEIJKGJ_01873 6.7e-139 focA P Formate/nitrite transporter
COEIJKGJ_01874 7e-150 sacT K transcriptional antiterminator
COEIJKGJ_01876 0.0 vpr O Belongs to the peptidase S8 family
COEIJKGJ_01877 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COEIJKGJ_01878 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
COEIJKGJ_01879 8.6e-202 rodA D Belongs to the SEDS family
COEIJKGJ_01880 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
COEIJKGJ_01881 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
COEIJKGJ_01882 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
COEIJKGJ_01883 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
COEIJKGJ_01884 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
COEIJKGJ_01885 1e-35 ywzA S membrane
COEIJKGJ_01886 2.6e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COEIJKGJ_01887 1.9e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COEIJKGJ_01888 9.5e-60 gtcA S GtrA-like protein
COEIJKGJ_01889 1.1e-121 ywcC K transcriptional regulator
COEIJKGJ_01891 9.8e-49 ywcB S Protein of unknown function, DUF485
COEIJKGJ_01892 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COEIJKGJ_01893 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
COEIJKGJ_01894 3.2e-223 ywbN P Dyp-type peroxidase family protein
COEIJKGJ_01895 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
COEIJKGJ_01896 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
COEIJKGJ_01897 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COEIJKGJ_01898 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COEIJKGJ_01899 4.3e-153 ywbI K Transcriptional regulator
COEIJKGJ_01900 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
COEIJKGJ_01901 2.3e-111 ywbG M effector of murein hydrolase
COEIJKGJ_01902 8.1e-208 ywbF EGP Major facilitator Superfamily
COEIJKGJ_01903 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
COEIJKGJ_01904 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
COEIJKGJ_01905 9.9e-67 ywbC 4.4.1.5 E glyoxalase
COEIJKGJ_01906 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
COEIJKGJ_01907 8.3e-125 ywbB S Protein of unknown function (DUF2711)
COEIJKGJ_01908 1.4e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEIJKGJ_01909 2.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
COEIJKGJ_01910 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEIJKGJ_01911 7.6e-152 sacY K transcriptional antiterminator
COEIJKGJ_01912 4.5e-168 gspA M General stress
COEIJKGJ_01913 1.5e-124 ywaF S Integral membrane protein
COEIJKGJ_01914 1.2e-86 ywaE K Transcriptional regulator
COEIJKGJ_01915 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COEIJKGJ_01916 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
COEIJKGJ_01917 4e-92 K Helix-turn-helix XRE-family like proteins
COEIJKGJ_01918 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
COEIJKGJ_01919 8.8e-130 ynfM EGP Major facilitator Superfamily
COEIJKGJ_01920 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
COEIJKGJ_01921 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
COEIJKGJ_01922 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_01923 3.6e-232 dltB M membrane protein involved in D-alanine export
COEIJKGJ_01924 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_01925 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COEIJKGJ_01926 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_01927 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
COEIJKGJ_01928 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
COEIJKGJ_01929 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
COEIJKGJ_01930 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEIJKGJ_01931 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
COEIJKGJ_01932 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
COEIJKGJ_01933 1.1e-19 yxzF
COEIJKGJ_01934 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COEIJKGJ_01935 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
COEIJKGJ_01936 1.6e-211 yxlH EGP Major facilitator Superfamily
COEIJKGJ_01937 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
COEIJKGJ_01938 8.2e-165 yxlF V ABC transporter, ATP-binding protein
COEIJKGJ_01939 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
COEIJKGJ_01940 1.4e-30
COEIJKGJ_01941 1.6e-46 yxlC S Family of unknown function (DUF5345)
COEIJKGJ_01942 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_01943 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
COEIJKGJ_01944 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COEIJKGJ_01945 0.0 cydD V ATP-binding protein
COEIJKGJ_01946 4e-309 cydD V ATP-binding
COEIJKGJ_01947 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
COEIJKGJ_01948 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
COEIJKGJ_01949 2.1e-228 cimH C COG3493 Na citrate symporter
COEIJKGJ_01950 2.3e-309 3.4.24.84 O Peptidase family M48
COEIJKGJ_01952 9.9e-152 yxkH G Polysaccharide deacetylase
COEIJKGJ_01953 5.9e-205 msmK P Belongs to the ABC transporter superfamily
COEIJKGJ_01954 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
COEIJKGJ_01955 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COEIJKGJ_01956 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COEIJKGJ_01957 2.8e-74 yxkC S Domain of unknown function (DUF4352)
COEIJKGJ_01958 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COEIJKGJ_01959 7.7e-77 S Protein of unknown function (DUF1453)
COEIJKGJ_01960 1.6e-190 yxjM T Signal transduction histidine kinase
COEIJKGJ_01961 9.8e-115 K helix_turn_helix, Lux Regulon
COEIJKGJ_01962 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COEIJKGJ_01964 1.4e-86 yxjI S LURP-one-related
COEIJKGJ_01965 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
COEIJKGJ_01966 1e-220 yxjG 2.1.1.14 E Methionine synthase
COEIJKGJ_01967 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
COEIJKGJ_01968 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
COEIJKGJ_01969 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
COEIJKGJ_01970 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
COEIJKGJ_01971 5e-142 rlmA 2.1.1.187 Q Methyltransferase domain
COEIJKGJ_01972 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COEIJKGJ_01973 1.5e-102 T Domain of unknown function (DUF4163)
COEIJKGJ_01974 3e-47 yxiS
COEIJKGJ_01975 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
COEIJKGJ_01976 6.6e-224 citH C Citrate transporter
COEIJKGJ_01977 3.6e-142 exoK GH16 M licheninase activity
COEIJKGJ_01978 8.3e-151 licT K transcriptional antiterminator
COEIJKGJ_01979 2e-110
COEIJKGJ_01980 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
COEIJKGJ_01981 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
COEIJKGJ_01982 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
COEIJKGJ_01985 1.6e-48 yxiJ S YxiJ-like protein
COEIJKGJ_01986 3e-90 yxiI S Protein of unknown function (DUF2716)
COEIJKGJ_01987 3.8e-81
COEIJKGJ_01988 4.9e-46
COEIJKGJ_01989 3.7e-75 yxiG
COEIJKGJ_01990 6.4e-63
COEIJKGJ_01991 1.7e-84
COEIJKGJ_01992 1.5e-71 yxxG
COEIJKGJ_01993 0.0 wapA M COG3209 Rhs family protein
COEIJKGJ_01994 2.9e-168 yxxF EG EamA-like transporter family
COEIJKGJ_01995 1.1e-72 yxiE T Belongs to the universal stress protein A family
COEIJKGJ_01996 6.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COEIJKGJ_01997 4.3e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEIJKGJ_01998 3.6e-51
COEIJKGJ_01999 2.2e-78 S SMI1 / KNR4 family
COEIJKGJ_02000 0.0 S nuclease activity
COEIJKGJ_02001 3.6e-39 yxiC S Family of unknown function (DUF5344)
COEIJKGJ_02002 2.1e-21 S Domain of unknown function (DUF5082)
COEIJKGJ_02003 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
COEIJKGJ_02004 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
COEIJKGJ_02005 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
COEIJKGJ_02006 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
COEIJKGJ_02007 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
COEIJKGJ_02008 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
COEIJKGJ_02009 1.3e-249 lysP E amino acid
COEIJKGJ_02010 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
COEIJKGJ_02011 8.3e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
COEIJKGJ_02012 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
COEIJKGJ_02013 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
COEIJKGJ_02014 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
COEIJKGJ_02015 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
COEIJKGJ_02016 2e-255 yxeQ S MmgE/PrpD family
COEIJKGJ_02017 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
COEIJKGJ_02018 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
COEIJKGJ_02019 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
COEIJKGJ_02020 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
COEIJKGJ_02021 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEIJKGJ_02022 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COEIJKGJ_02024 1.2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
COEIJKGJ_02025 1.4e-150 yidA S hydrolases of the HAD superfamily
COEIJKGJ_02028 1.3e-20 yxeE
COEIJKGJ_02029 1.9e-16 yxeD
COEIJKGJ_02030 8.5e-69
COEIJKGJ_02031 1.9e-175 fhuD P ABC transporter
COEIJKGJ_02032 1.5e-58 yxeA S Protein of unknown function (DUF1093)
COEIJKGJ_02033 0.0 yxdM V ABC transporter (permease)
COEIJKGJ_02034 9.4e-141 yxdL V ABC transporter, ATP-binding protein
COEIJKGJ_02035 4.8e-182 T PhoQ Sensor
COEIJKGJ_02036 1.2e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_02037 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
COEIJKGJ_02038 2.3e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
COEIJKGJ_02039 8.6e-167 iolH G Xylose isomerase-like TIM barrel
COEIJKGJ_02040 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
COEIJKGJ_02041 5.1e-235 iolF EGP Major facilitator Superfamily
COEIJKGJ_02042 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
COEIJKGJ_02043 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
COEIJKGJ_02044 1.4e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
COEIJKGJ_02045 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
COEIJKGJ_02046 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COEIJKGJ_02047 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
COEIJKGJ_02048 8.3e-176 iolS C Aldo keto reductase
COEIJKGJ_02050 8.3e-48 yxcD S Protein of unknown function (DUF2653)
COEIJKGJ_02051 2.3e-246 csbC EGP Major facilitator Superfamily
COEIJKGJ_02052 0.0 htpG O Molecular chaperone. Has ATPase activity
COEIJKGJ_02054 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
COEIJKGJ_02055 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
COEIJKGJ_02056 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
COEIJKGJ_02057 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
COEIJKGJ_02058 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
COEIJKGJ_02059 3.3e-127 yxbB Q Met-10+ like-protein
COEIJKGJ_02060 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
COEIJKGJ_02061 1.1e-86 yxnB
COEIJKGJ_02062 0.0 asnB 6.3.5.4 E Asparagine synthase
COEIJKGJ_02063 7.6e-214 yxaM U MFS_1 like family
COEIJKGJ_02064 6.8e-93 S PQQ-like domain
COEIJKGJ_02065 3.5e-65 S Family of unknown function (DUF5391)
COEIJKGJ_02066 1.1e-75 yxaI S membrane protein domain
COEIJKGJ_02067 1.4e-228 P Protein of unknown function (DUF418)
COEIJKGJ_02068 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
COEIJKGJ_02069 1.2e-100 yxaF K Transcriptional regulator
COEIJKGJ_02070 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_02071 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
COEIJKGJ_02072 5.2e-50 S LrgA family
COEIJKGJ_02073 1.3e-117 yxaC M effector of murein hydrolase
COEIJKGJ_02074 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
COEIJKGJ_02075 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COEIJKGJ_02076 2.8e-126 gntR K transcriptional
COEIJKGJ_02077 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
COEIJKGJ_02078 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
COEIJKGJ_02079 5e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COEIJKGJ_02080 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
COEIJKGJ_02081 1.9e-286 ahpF O Alkyl hydroperoxide reductase
COEIJKGJ_02082 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COEIJKGJ_02083 3.4e-27 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
COEIJKGJ_02084 1.9e-124 yydK K Transcriptional regulator
COEIJKGJ_02085 1.6e-118 S ABC-2 family transporter protein
COEIJKGJ_02086 1.6e-109 prrC P ABC transporter
COEIJKGJ_02087 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
COEIJKGJ_02088 1.3e-202 S SIR2-like domain
COEIJKGJ_02089 1.1e-180 L DNA synthesis involved in DNA repair
COEIJKGJ_02090 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COEIJKGJ_02091 1.1e-09 S YyzF-like protein
COEIJKGJ_02092 1.3e-67
COEIJKGJ_02093 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
COEIJKGJ_02095 1.7e-30 yycQ S Protein of unknown function (DUF2651)
COEIJKGJ_02096 5.4e-201 yycP
COEIJKGJ_02097 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
COEIJKGJ_02098 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
COEIJKGJ_02099 1.1e-187 S aspartate phosphatase
COEIJKGJ_02101 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
COEIJKGJ_02102 1.3e-260 rocE E amino acid
COEIJKGJ_02103 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
COEIJKGJ_02104 7.4e-16
COEIJKGJ_02105 2.8e-94
COEIJKGJ_02106 2.3e-24 S Sporulation delaying protein SdpA
COEIJKGJ_02107 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
COEIJKGJ_02108 1.5e-40 sdpR K transcriptional
COEIJKGJ_02109 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
COEIJKGJ_02110 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
COEIJKGJ_02111 1.5e-94 K PFAM response regulator receiver
COEIJKGJ_02112 2.6e-73 S Peptidase propeptide and YPEB domain
COEIJKGJ_02113 5.5e-33 S Peptidase propeptide and YPEB domain
COEIJKGJ_02114 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COEIJKGJ_02115 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
COEIJKGJ_02116 1.8e-153 yycI S protein conserved in bacteria
COEIJKGJ_02117 3.1e-259 yycH S protein conserved in bacteria
COEIJKGJ_02118 0.0 vicK 2.7.13.3 T Histidine kinase
COEIJKGJ_02119 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_02124 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COEIJKGJ_02125 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COEIJKGJ_02126 1.2e-250 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COEIJKGJ_02127 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
COEIJKGJ_02129 1.9e-15 yycC K YycC-like protein
COEIJKGJ_02130 8.4e-221 yeaN P COG2807 Cyanate permease
COEIJKGJ_02131 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COEIJKGJ_02132 2.2e-73 rplI J binds to the 23S rRNA
COEIJKGJ_02133 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COEIJKGJ_02134 8.3e-160 yybS S membrane
COEIJKGJ_02136 3.3e-83 cotF M Spore coat protein
COEIJKGJ_02137 1.7e-66 ydeP3 K Transcriptional regulator
COEIJKGJ_02138 8.1e-163 ppaC 3.6.1.1 C Inorganic pyrophosphatase
COEIJKGJ_02139 3.6e-60
COEIJKGJ_02141 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
COEIJKGJ_02142 2.2e-110 K TipAS antibiotic-recognition domain
COEIJKGJ_02143 4.8e-124
COEIJKGJ_02144 2.9e-66 yybH S SnoaL-like domain
COEIJKGJ_02145 3.5e-54 yybG S Pentapeptide repeat-containing protein
COEIJKGJ_02146 2.2e-216 ynfM EGP Major facilitator Superfamily
COEIJKGJ_02147 4e-164 yybE K Transcriptional regulator
COEIJKGJ_02148 7.7e-79 yjcF S Acetyltransferase (GNAT) domain
COEIJKGJ_02149 1.6e-74 yybC
COEIJKGJ_02150 7.3e-126 S Metallo-beta-lactamase superfamily
COEIJKGJ_02151 5.6e-77 yybA 2.3.1.57 K transcriptional
COEIJKGJ_02152 2e-71 yjcF S Acetyltransferase (GNAT) domain
COEIJKGJ_02153 5.5e-96 yyaS S Membrane
COEIJKGJ_02154 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
COEIJKGJ_02155 1.3e-65 yyaQ S YjbR
COEIJKGJ_02156 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
COEIJKGJ_02157 6.6e-246 tetL EGP Major facilitator Superfamily
COEIJKGJ_02158 2.3e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
COEIJKGJ_02160 4.1e-11 S Putative amidase domain
COEIJKGJ_02161 5.1e-61 yyaN K MerR HTH family regulatory protein
COEIJKGJ_02162 2.8e-160 yyaM EG EamA-like transporter family
COEIJKGJ_02163 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
COEIJKGJ_02164 3.6e-168 yyaK S CAAX protease self-immunity
COEIJKGJ_02165 2.3e-243 EGP Major facilitator superfamily
COEIJKGJ_02166 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
COEIJKGJ_02167 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COEIJKGJ_02168 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
COEIJKGJ_02169 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
COEIJKGJ_02170 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COEIJKGJ_02171 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COEIJKGJ_02172 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
COEIJKGJ_02173 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COEIJKGJ_02174 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COEIJKGJ_02175 2.3e-33 yyzM S protein conserved in bacteria
COEIJKGJ_02176 8.1e-177 yyaD S Membrane
COEIJKGJ_02177 1.6e-111 yyaC S Sporulation protein YyaC
COEIJKGJ_02178 2.1e-149 spo0J K Belongs to the ParB family
COEIJKGJ_02179 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
COEIJKGJ_02180 9.6e-74 S Bacterial PH domain
COEIJKGJ_02181 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
COEIJKGJ_02182 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
COEIJKGJ_02183 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COEIJKGJ_02184 5.8e-250 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COEIJKGJ_02185 6.5e-108 jag S single-stranded nucleic acid binding R3H
COEIJKGJ_02186 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COEIJKGJ_02187 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COEIJKGJ_02188 7.8e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COEIJKGJ_02189 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COEIJKGJ_02190 2.4e-33 yaaA S S4 domain
COEIJKGJ_02191 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COEIJKGJ_02192 1.8e-37 yaaB S Domain of unknown function (DUF370)
COEIJKGJ_02193 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COEIJKGJ_02194 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COEIJKGJ_02199 7.8e-08
COEIJKGJ_02207 2e-08
COEIJKGJ_02211 2.7e-143 spo0M S COG4326 Sporulation control protein
COEIJKGJ_02212 1.2e-26
COEIJKGJ_02213 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
COEIJKGJ_02214 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
COEIJKGJ_02215 1.9e-266 ygaK C Berberine and berberine like
COEIJKGJ_02217 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
COEIJKGJ_02218 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
COEIJKGJ_02219 1.7e-171 ssuA M Sulfonate ABC transporter
COEIJKGJ_02220 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
COEIJKGJ_02221 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
COEIJKGJ_02223 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COEIJKGJ_02224 4.1e-78 ygaO
COEIJKGJ_02225 4.8e-29 K Transcriptional regulator
COEIJKGJ_02227 7.9e-114 yhzB S B3/4 domain
COEIJKGJ_02228 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
COEIJKGJ_02229 4.4e-177 yhbB S Putative amidase domain
COEIJKGJ_02230 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COEIJKGJ_02231 1.2e-109 yhbD K Protein of unknown function (DUF4004)
COEIJKGJ_02232 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
COEIJKGJ_02233 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
COEIJKGJ_02234 0.0 prkA T Ser protein kinase
COEIJKGJ_02235 2.5e-225 yhbH S Belongs to the UPF0229 family
COEIJKGJ_02236 2.2e-76 yhbI K DNA-binding transcription factor activity
COEIJKGJ_02237 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
COEIJKGJ_02238 3.1e-271 yhcA EGP Major facilitator Superfamily
COEIJKGJ_02239 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
COEIJKGJ_02240 2.8e-37 yhcC
COEIJKGJ_02241 3.5e-55
COEIJKGJ_02242 1.5e-59 yhcF K Transcriptional regulator
COEIJKGJ_02243 4.4e-121 yhcG V ABC transporter, ATP-binding protein
COEIJKGJ_02244 6.5e-165 yhcH V ABC transporter, ATP-binding protein
COEIJKGJ_02245 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
COEIJKGJ_02246 1e-30 cspB K Cold-shock protein
COEIJKGJ_02247 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
COEIJKGJ_02248 1.9e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
COEIJKGJ_02249 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COEIJKGJ_02250 1.1e-77 S Protein of unknown function (DUF2812)
COEIJKGJ_02251 1.2e-49 K Transcriptional regulator PadR-like family
COEIJKGJ_02252 2e-41 yhcM
COEIJKGJ_02253 1.3e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
COEIJKGJ_02254 2.5e-167 yhcP
COEIJKGJ_02255 5.2e-100 yhcQ M Spore coat protein
COEIJKGJ_02256 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
COEIJKGJ_02257 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
COEIJKGJ_02258 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COEIJKGJ_02259 9.3e-68 yhcU S Family of unknown function (DUF5365)
COEIJKGJ_02260 9.9e-68 yhcV S COG0517 FOG CBS domain
COEIJKGJ_02261 4.6e-120 yhcW 5.4.2.6 S hydrolase
COEIJKGJ_02262 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
COEIJKGJ_02263 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COEIJKGJ_02264 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
COEIJKGJ_02265 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
COEIJKGJ_02266 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COEIJKGJ_02267 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
COEIJKGJ_02268 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
COEIJKGJ_02269 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
COEIJKGJ_02270 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COEIJKGJ_02271 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
COEIJKGJ_02272 1.2e-38 yhdB S YhdB-like protein
COEIJKGJ_02273 4.8e-54 yhdC S Protein of unknown function (DUF3889)
COEIJKGJ_02274 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
COEIJKGJ_02275 1e-75 nsrR K Transcriptional regulator
COEIJKGJ_02276 3.6e-237 ygxB M Conserved TM helix
COEIJKGJ_02277 6.3e-276 ycgB S Stage V sporulation protein R
COEIJKGJ_02278 5e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
COEIJKGJ_02279 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
COEIJKGJ_02280 3.8e-162 citR K Transcriptional regulator
COEIJKGJ_02281 1.3e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
COEIJKGJ_02282 2.7e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_02283 3.4e-250 yhdG E amino acid
COEIJKGJ_02284 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
COEIJKGJ_02285 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COEIJKGJ_02286 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEIJKGJ_02287 8.1e-45 yhdK S Sigma-M inhibitor protein
COEIJKGJ_02288 1.5e-200 yhdL S Sigma factor regulator N-terminal
COEIJKGJ_02289 1e-84 sigM K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_02290 1.7e-190 yhdN C Aldo keto reductase
COEIJKGJ_02291 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
COEIJKGJ_02292 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
COEIJKGJ_02293 4.1e-74 cueR K transcriptional
COEIJKGJ_02294 4.4e-222 yhdR 2.6.1.1 E Aminotransferase
COEIJKGJ_02295 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
COEIJKGJ_02296 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COEIJKGJ_02297 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COEIJKGJ_02298 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COEIJKGJ_02300 1.6e-202 yhdY M Mechanosensitive ion channel
COEIJKGJ_02301 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
COEIJKGJ_02302 5.3e-137 yheN G deacetylase
COEIJKGJ_02303 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
COEIJKGJ_02304 3.7e-225 nhaC C Na H antiporter
COEIJKGJ_02305 5.4e-82 nhaX T Belongs to the universal stress protein A family
COEIJKGJ_02306 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
COEIJKGJ_02307 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
COEIJKGJ_02308 7.6e-109 yheG GM NAD(P)H-binding
COEIJKGJ_02309 6.3e-28 sspB S spore protein
COEIJKGJ_02310 1.3e-36 yheE S Family of unknown function (DUF5342)
COEIJKGJ_02311 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
COEIJKGJ_02312 4.3e-216 yheC HJ YheC/D like ATP-grasp
COEIJKGJ_02313 1.8e-201 yheB S Belongs to the UPF0754 family
COEIJKGJ_02314 9.5e-48 yheA S Belongs to the UPF0342 family
COEIJKGJ_02315 2e-205 yhaZ L DNA alkylation repair enzyme
COEIJKGJ_02316 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
COEIJKGJ_02317 3.9e-292 hemZ H coproporphyrinogen III oxidase
COEIJKGJ_02318 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
COEIJKGJ_02319 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
COEIJKGJ_02321 2.3e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
COEIJKGJ_02322 1.1e-26 S YhzD-like protein
COEIJKGJ_02323 1.2e-166 yhaQ S ABC transporter, ATP-binding protein
COEIJKGJ_02324 1.6e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
COEIJKGJ_02325 2.2e-224 yhaO L DNA repair exonuclease
COEIJKGJ_02326 0.0 yhaN L AAA domain
COEIJKGJ_02327 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
COEIJKGJ_02328 1.6e-21 yhaL S Sporulation protein YhaL
COEIJKGJ_02329 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COEIJKGJ_02330 8.7e-90 yhaK S Putative zincin peptidase
COEIJKGJ_02331 1.3e-54 yhaI S Protein of unknown function (DUF1878)
COEIJKGJ_02332 1e-113 hpr K Negative regulator of protease production and sporulation
COEIJKGJ_02333 7e-39 yhaH S YtxH-like protein
COEIJKGJ_02334 3.6e-80 trpP S Tryptophan transporter TrpP
COEIJKGJ_02335 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COEIJKGJ_02336 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
COEIJKGJ_02337 4.6e-137 ecsA V transporter (ATP-binding protein)
COEIJKGJ_02338 1.8e-215 ecsB U ABC transporter
COEIJKGJ_02339 1.4e-114 ecsC S EcsC protein family
COEIJKGJ_02340 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
COEIJKGJ_02341 2.7e-231 yhfA C membrane
COEIJKGJ_02342 7.9e-27 1.15.1.2 C Rubrerythrin
COEIJKGJ_02343 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
COEIJKGJ_02344 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COEIJKGJ_02345 1.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
COEIJKGJ_02346 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
COEIJKGJ_02347 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
COEIJKGJ_02348 5.4e-101 yhgD K Transcriptional regulator
COEIJKGJ_02349 2.5e-237 yhgE S YhgE Pip N-terminal domain protein
COEIJKGJ_02350 4.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COEIJKGJ_02351 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
COEIJKGJ_02352 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
COEIJKGJ_02353 1.7e-72 3.4.13.21 S ASCH
COEIJKGJ_02354 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COEIJKGJ_02355 2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
COEIJKGJ_02356 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
COEIJKGJ_02357 1.9e-110 yhfK GM NmrA-like family
COEIJKGJ_02358 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
COEIJKGJ_02359 1.9e-65 yhfM
COEIJKGJ_02360 3.5e-241 yhfN 3.4.24.84 O Peptidase M48
COEIJKGJ_02361 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
COEIJKGJ_02362 3.1e-75 VY92_01935 K acetyltransferase
COEIJKGJ_02363 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
COEIJKGJ_02364 4.3e-159 yfmC M Periplasmic binding protein
COEIJKGJ_02365 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
COEIJKGJ_02366 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
COEIJKGJ_02367 6.4e-268 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
COEIJKGJ_02368 6.5e-91 bioY S BioY family
COEIJKGJ_02369 1.7e-182 hemAT NT chemotaxis protein
COEIJKGJ_02370 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
COEIJKGJ_02371 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_02372 1.3e-32 yhzC S IDEAL
COEIJKGJ_02373 4.2e-109 comK K Competence transcription factor
COEIJKGJ_02374 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
COEIJKGJ_02375 7.8e-42 yhjA S Excalibur calcium-binding domain
COEIJKGJ_02376 1.3e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COEIJKGJ_02377 6.9e-27 yhjC S Protein of unknown function (DUF3311)
COEIJKGJ_02378 6.7e-60 yhjD
COEIJKGJ_02379 3.4e-109 yhjE S SNARE associated Golgi protein
COEIJKGJ_02380 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
COEIJKGJ_02381 2.4e-278 yhjG CH FAD binding domain
COEIJKGJ_02382 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
COEIJKGJ_02383 4.5e-214 glcP G Major Facilitator Superfamily
COEIJKGJ_02384 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
COEIJKGJ_02385 4.5e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
COEIJKGJ_02386 7.7e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
COEIJKGJ_02387 1.6e-188 yhjM 5.1.1.1 K Transcriptional regulator
COEIJKGJ_02388 5.1e-199 abrB S membrane
COEIJKGJ_02389 7.9e-211 EGP Transmembrane secretion effector
COEIJKGJ_02390 0.0 S Sugar transport-related sRNA regulator N-term
COEIJKGJ_02391 2.7e-33 yhjQ C COG1145 Ferredoxin
COEIJKGJ_02392 1.1e-77 yhjR S Rubrerythrin
COEIJKGJ_02393 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
COEIJKGJ_02394 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COEIJKGJ_02395 6.9e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COEIJKGJ_02396 0.0 sbcC L COG0419 ATPase involved in DNA repair
COEIJKGJ_02397 1.1e-49 yisB V COG1403 Restriction endonuclease
COEIJKGJ_02398 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
COEIJKGJ_02399 3e-66 gerPE S Spore germination protein GerPE
COEIJKGJ_02400 6.3e-24 gerPD S Spore germination protein
COEIJKGJ_02401 1.8e-54 gerPC S Spore germination protein
COEIJKGJ_02402 4e-34 gerPB S cell differentiation
COEIJKGJ_02403 1.9e-33 gerPA S Spore germination protein
COEIJKGJ_02404 1.5e-22 yisI S Spo0E like sporulation regulatory protein
COEIJKGJ_02405 1.1e-172 cotH M Spore Coat
COEIJKGJ_02406 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
COEIJKGJ_02407 3.9e-57 yisL S UPF0344 protein
COEIJKGJ_02408 0.0 wprA O Belongs to the peptidase S8 family
COEIJKGJ_02409 2.1e-102 yisN S Protein of unknown function (DUF2777)
COEIJKGJ_02410 0.0 asnO 6.3.5.4 E Asparagine synthase
COEIJKGJ_02411 3.9e-87 yizA S Damage-inducible protein DinB
COEIJKGJ_02412 2.8e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
COEIJKGJ_02413 1.5e-242 yisQ V Mate efflux family protein
COEIJKGJ_02414 1.2e-160 yisR K Transcriptional regulator
COEIJKGJ_02415 1.5e-183 purR K helix_turn _helix lactose operon repressor
COEIJKGJ_02416 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
COEIJKGJ_02417 7e-92 yisT S DinB family
COEIJKGJ_02418 1.9e-107 argO S Lysine exporter protein LysE YggA
COEIJKGJ_02419 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COEIJKGJ_02420 4e-36 mcbG S Pentapeptide repeats (9 copies)
COEIJKGJ_02421 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COEIJKGJ_02422 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
COEIJKGJ_02423 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
COEIJKGJ_02424 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
COEIJKGJ_02425 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
COEIJKGJ_02426 5.4e-141 yitD 4.4.1.19 S synthase
COEIJKGJ_02427 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COEIJKGJ_02428 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
COEIJKGJ_02429 1.5e-228 yitG EGP Major facilitator Superfamily
COEIJKGJ_02430 2e-160 yitH K Acetyltransferase (GNAT) domain
COEIJKGJ_02431 7.8e-79 yjcF S Acetyltransferase (GNAT) domain
COEIJKGJ_02432 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
COEIJKGJ_02433 5.6e-54 yajQ S Belongs to the UPF0234 family
COEIJKGJ_02434 6.9e-161 cvfB S protein conserved in bacteria
COEIJKGJ_02435 8.5e-94
COEIJKGJ_02436 1.4e-170
COEIJKGJ_02437 1.5e-97 S Sporulation delaying protein SdpA
COEIJKGJ_02438 1.5e-58 K Transcriptional regulator PadR-like family
COEIJKGJ_02439 2e-95
COEIJKGJ_02440 1.4e-44 yitR S Domain of unknown function (DUF3784)
COEIJKGJ_02441 1.6e-307 nprB 3.4.24.28 E Peptidase M4
COEIJKGJ_02442 8.4e-159 yitS S protein conserved in bacteria
COEIJKGJ_02443 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
COEIJKGJ_02444 5e-73 ipi S Intracellular proteinase inhibitor
COEIJKGJ_02445 1.2e-17 S Protein of unknown function (DUF3813)
COEIJKGJ_02446 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
COEIJKGJ_02447 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
COEIJKGJ_02448 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
COEIJKGJ_02449 1.5e-22 pilT S Proteolipid membrane potential modulator
COEIJKGJ_02450 6e-266 yitY C D-arabinono-1,4-lactone oxidase
COEIJKGJ_02451 1.7e-88 norB G Major Facilitator Superfamily
COEIJKGJ_02452 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
COEIJKGJ_02453 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
COEIJKGJ_02454 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
COEIJKGJ_02455 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
COEIJKGJ_02456 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COEIJKGJ_02457 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
COEIJKGJ_02458 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COEIJKGJ_02459 9.5e-28 yjzC S YjzC-like protein
COEIJKGJ_02460 2.3e-16 yjzD S Protein of unknown function (DUF2929)
COEIJKGJ_02461 6.8e-141 yjaU I carboxylic ester hydrolase activity
COEIJKGJ_02462 1.8e-101 yjaV
COEIJKGJ_02463 1.1e-183 med S Transcriptional activator protein med
COEIJKGJ_02464 4.7e-25 comZ S ComZ
COEIJKGJ_02465 2.7e-22 yjzB
COEIJKGJ_02466 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COEIJKGJ_02467 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COEIJKGJ_02468 7.8e-151 yjaZ O Zn-dependent protease
COEIJKGJ_02469 1.8e-184 appD P Belongs to the ABC transporter superfamily
COEIJKGJ_02470 6.5e-187 appF E Belongs to the ABC transporter superfamily
COEIJKGJ_02471 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
COEIJKGJ_02472 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COEIJKGJ_02473 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COEIJKGJ_02474 6.5e-147 yjbA S Belongs to the UPF0736 family
COEIJKGJ_02475 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
COEIJKGJ_02476 0.0 oppA E ABC transporter substrate-binding protein
COEIJKGJ_02477 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COEIJKGJ_02478 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COEIJKGJ_02479 1.5e-197 oppD P Belongs to the ABC transporter superfamily
COEIJKGJ_02480 5.5e-172 oppF E Belongs to the ABC transporter superfamily
COEIJKGJ_02481 1.2e-203 yjbB EGP Major Facilitator Superfamily
COEIJKGJ_02482 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEIJKGJ_02483 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COEIJKGJ_02484 6e-112 yjbE P Integral membrane protein TerC family
COEIJKGJ_02485 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
COEIJKGJ_02486 2.1e-221 yjbF S Competence protein
COEIJKGJ_02487 0.0 pepF E oligoendopeptidase F
COEIJKGJ_02488 1.8e-20
COEIJKGJ_02490 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
COEIJKGJ_02491 1.1e-71 yjbI S Bacterial-like globin
COEIJKGJ_02492 3.8e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
COEIJKGJ_02493 1e-99 yjbK S protein conserved in bacteria
COEIJKGJ_02494 1.6e-61 yjbL S Belongs to the UPF0738 family
COEIJKGJ_02495 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
COEIJKGJ_02496 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COEIJKGJ_02497 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COEIJKGJ_02498 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
COEIJKGJ_02499 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COEIJKGJ_02500 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
COEIJKGJ_02501 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
COEIJKGJ_02502 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
COEIJKGJ_02503 2.6e-29 thiS H thiamine diphosphate biosynthetic process
COEIJKGJ_02504 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
COEIJKGJ_02505 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
COEIJKGJ_02506 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COEIJKGJ_02507 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
COEIJKGJ_02508 5.9e-54 yjbX S Spore coat protein
COEIJKGJ_02509 4.4e-82 cotZ S Spore coat protein
COEIJKGJ_02510 7.6e-96 cotY S Spore coat protein Z
COEIJKGJ_02511 1.6e-72 cotX S Spore Coat Protein X and V domain
COEIJKGJ_02512 8.8e-24 cotW
COEIJKGJ_02513 1.1e-54 cotV S Spore Coat Protein X and V domain
COEIJKGJ_02514 4.3e-56 yjcA S Protein of unknown function (DUF1360)
COEIJKGJ_02517 2.9e-38 spoVIF S Stage VI sporulation protein F
COEIJKGJ_02518 0.0 yjcD 3.6.4.12 L DNA helicase
COEIJKGJ_02519 1.7e-38
COEIJKGJ_02520 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEIJKGJ_02521 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
COEIJKGJ_02522 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
COEIJKGJ_02523 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COEIJKGJ_02524 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COEIJKGJ_02525 7.7e-97 rimJ 2.3.1.128 J Alanine acetyltransferase
COEIJKGJ_02526 5.4e-212 yjcL S Protein of unknown function (DUF819)
COEIJKGJ_02529 7.8e-190 S Putative amidase domain
COEIJKGJ_02530 2.6e-44 yjcN
COEIJKGJ_02533 8.5e-81 L Transposase
COEIJKGJ_02534 5.3e-71 yjcP
COEIJKGJ_02535 4.1e-49 S YjcQ protein
COEIJKGJ_02536 1.1e-92 yqaS L DNA packaging
COEIJKGJ_02537 2.4e-33 yjcS S Antibiotic biosynthesis monooxygenase
COEIJKGJ_02538 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
COEIJKGJ_02540 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
COEIJKGJ_02541 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
COEIJKGJ_02542 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
COEIJKGJ_02543 4.5e-49 yjdF S Protein of unknown function (DUF2992)
COEIJKGJ_02544 4.5e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
COEIJKGJ_02546 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COEIJKGJ_02547 4.2e-29 S Domain of unknown function (DUF4177)
COEIJKGJ_02548 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
COEIJKGJ_02549 1.4e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
COEIJKGJ_02551 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
COEIJKGJ_02552 1.4e-81 S Protein of unknown function (DUF2690)
COEIJKGJ_02553 8.9e-20 yjfB S Putative motility protein
COEIJKGJ_02554 5.6e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
COEIJKGJ_02555 1.2e-45 T PhoQ Sensor
COEIJKGJ_02556 8.9e-104 yjgB S Domain of unknown function (DUF4309)
COEIJKGJ_02557 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
COEIJKGJ_02558 4.3e-95 yjgD S Protein of unknown function (DUF1641)
COEIJKGJ_02559 8.7e-07 S Domain of unknown function (DUF4352)
COEIJKGJ_02560 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
COEIJKGJ_02562 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
COEIJKGJ_02563 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
COEIJKGJ_02564 8.2e-30
COEIJKGJ_02565 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
COEIJKGJ_02566 1.9e-122 ybbM S transport system, permease component
COEIJKGJ_02567 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
COEIJKGJ_02568 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
COEIJKGJ_02569 2.8e-93 yjlB S Cupin domain
COEIJKGJ_02570 7.1e-66 yjlC S Protein of unknown function (DUF1641)
COEIJKGJ_02571 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
COEIJKGJ_02572 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
COEIJKGJ_02573 5.8e-250 yjmB G symporter YjmB
COEIJKGJ_02574 4.3e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
COEIJKGJ_02575 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
COEIJKGJ_02576 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
COEIJKGJ_02577 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
COEIJKGJ_02578 3.7e-227 exuT G Sugar (and other) transporter
COEIJKGJ_02579 2.3e-184 exuR K transcriptional
COEIJKGJ_02580 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
COEIJKGJ_02581 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
COEIJKGJ_02582 7.4e-130 MA20_18170 S membrane transporter protein
COEIJKGJ_02583 2.3e-78 yjoA S DinB family
COEIJKGJ_02584 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
COEIJKGJ_02585 1e-212 S response regulator aspartate phosphatase
COEIJKGJ_02587 5.2e-37 S YCII-related domain
COEIJKGJ_02588 6.8e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
COEIJKGJ_02589 1.8e-60 yjqA S Bacterial PH domain
COEIJKGJ_02590 2.1e-111 yjqB S Pfam:DUF867
COEIJKGJ_02591 9.8e-160 ydbD P Catalase
COEIJKGJ_02592 4.3e-109 xkdA E IrrE N-terminal-like domain
COEIJKGJ_02593 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
COEIJKGJ_02595 5e-156 xkdB K sequence-specific DNA binding
COEIJKGJ_02596 9.2e-118 xkdC L Bacterial dnaA protein
COEIJKGJ_02599 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
COEIJKGJ_02600 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
COEIJKGJ_02601 5.3e-139 xtmA L phage terminase small subunit
COEIJKGJ_02602 1.4e-253 xtmB S phage terminase, large subunit
COEIJKGJ_02603 6e-285 yqbA S portal protein
COEIJKGJ_02604 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
COEIJKGJ_02605 1.3e-168 xkdG S Phage capsid family
COEIJKGJ_02606 5.5e-65 yqbG S Protein of unknown function (DUF3199)
COEIJKGJ_02607 8.7e-65 yqbH S Domain of unknown function (DUF3599)
COEIJKGJ_02608 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
COEIJKGJ_02609 1.9e-77 xkdJ
COEIJKGJ_02610 2.5e-256 xkdK S Phage tail sheath C-terminal domain
COEIJKGJ_02611 6.1e-76 xkdM S Phage tail tube protein
COEIJKGJ_02612 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
COEIJKGJ_02613 0.0 xkdO L Transglycosylase SLT domain
COEIJKGJ_02614 4.1e-121 xkdP S Lysin motif
COEIJKGJ_02615 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
COEIJKGJ_02616 2.1e-39 xkdR S Protein of unknown function (DUF2577)
COEIJKGJ_02617 3.1e-69 xkdS S Protein of unknown function (DUF2634)
COEIJKGJ_02618 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
COEIJKGJ_02619 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
COEIJKGJ_02620 1.5e-40
COEIJKGJ_02621 1e-261
COEIJKGJ_02622 5.4e-53 xkdW S XkdW protein
COEIJKGJ_02623 5.5e-22 xkdX
COEIJKGJ_02624 1.7e-151 xepA
COEIJKGJ_02625 6.2e-39 xhlA S Haemolysin XhlA
COEIJKGJ_02626 9.3e-40 xhlB S SPP1 phage holin
COEIJKGJ_02627 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COEIJKGJ_02628 6.7e-23 spoIISB S Stage II sporulation protein SB
COEIJKGJ_02629 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
COEIJKGJ_02630 5.8e-175 pit P phosphate transporter
COEIJKGJ_02631 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
COEIJKGJ_02632 4e-240 steT E amino acid
COEIJKGJ_02633 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
COEIJKGJ_02634 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COEIJKGJ_02635 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COEIJKGJ_02637 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
COEIJKGJ_02638 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
COEIJKGJ_02639 2.5e-152 dppA E D-aminopeptidase
COEIJKGJ_02640 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COEIJKGJ_02641 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
COEIJKGJ_02642 1.3e-187 dppD P Belongs to the ABC transporter superfamily
COEIJKGJ_02643 0.0 dppE E ABC transporter substrate-binding protein
COEIJKGJ_02645 1.3e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
COEIJKGJ_02646 2.3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
COEIJKGJ_02647 2.7e-163 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
COEIJKGJ_02648 9.4e-186 ykfD E Belongs to the ABC transporter superfamily
COEIJKGJ_02649 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
COEIJKGJ_02650 2e-160 ykgA E Amidinotransferase
COEIJKGJ_02651 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
COEIJKGJ_02652 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
COEIJKGJ_02653 5.5e-09
COEIJKGJ_02654 7.8e-129 ykjA S Protein of unknown function (DUF421)
COEIJKGJ_02655 4.8e-96 ykkA S Protein of unknown function (DUF664)
COEIJKGJ_02656 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
COEIJKGJ_02657 3.5e-55 ykkC P Multidrug resistance protein
COEIJKGJ_02658 7e-50 ykkD P Multidrug resistance protein
COEIJKGJ_02659 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
COEIJKGJ_02660 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COEIJKGJ_02661 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COEIJKGJ_02662 1.3e-70 ohrA O Organic hydroperoxide resistance protein
COEIJKGJ_02663 4.8e-73 ohrR K COG1846 Transcriptional regulators
COEIJKGJ_02664 2.4e-71 ohrB O Organic hydroperoxide resistance protein
COEIJKGJ_02666 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
COEIJKGJ_02667 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COEIJKGJ_02668 1.6e-174 isp O Belongs to the peptidase S8 family
COEIJKGJ_02669 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COEIJKGJ_02670 5.3e-136 ykoC P Cobalt transport protein
COEIJKGJ_02671 2.2e-304 P ABC transporter, ATP-binding protein
COEIJKGJ_02672 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
COEIJKGJ_02673 1.6e-108 ykoF S YKOF-related Family
COEIJKGJ_02674 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_02675 1.4e-240 ykoH 2.7.13.3 T Histidine kinase
COEIJKGJ_02676 9.9e-110 ykoI S Peptidase propeptide and YPEB domain
COEIJKGJ_02677 8.3e-85 ykoJ S Peptidase propeptide and YPEB domain
COEIJKGJ_02680 2.2e-222 mgtE P Acts as a magnesium transporter
COEIJKGJ_02681 1.4e-53 tnrA K transcriptional
COEIJKGJ_02682 5.9e-18
COEIJKGJ_02683 6.9e-26 ykoL
COEIJKGJ_02684 1.3e-81 mhqR K transcriptional
COEIJKGJ_02685 3.1e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
COEIJKGJ_02686 1.4e-98 ykoP G polysaccharide deacetylase
COEIJKGJ_02687 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
COEIJKGJ_02688 0.0 ykoS
COEIJKGJ_02689 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COEIJKGJ_02690 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
COEIJKGJ_02691 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
COEIJKGJ_02692 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
COEIJKGJ_02693 3.5e-109 ykoX S membrane-associated protein
COEIJKGJ_02694 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
COEIJKGJ_02695 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COEIJKGJ_02696 9.1e-116 rsgI S Anti-sigma factor N-terminus
COEIJKGJ_02697 1.9e-26 sspD S small acid-soluble spore protein
COEIJKGJ_02698 1.5e-124 ykrK S Domain of unknown function (DUF1836)
COEIJKGJ_02699 3.5e-155 htpX O Belongs to the peptidase M48B family
COEIJKGJ_02700 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
COEIJKGJ_02701 1.2e-10 ydfR S Protein of unknown function (DUF421)
COEIJKGJ_02702 4.1e-18 ykzE
COEIJKGJ_02703 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
COEIJKGJ_02704 0.0 kinE 2.7.13.3 T Histidine kinase
COEIJKGJ_02705 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COEIJKGJ_02707 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
COEIJKGJ_02708 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
COEIJKGJ_02709 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
COEIJKGJ_02710 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
COEIJKGJ_02711 1.4e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
COEIJKGJ_02712 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
COEIJKGJ_02713 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
COEIJKGJ_02714 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
COEIJKGJ_02715 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
COEIJKGJ_02716 6.4e-09 S Spo0E like sporulation regulatory protein
COEIJKGJ_02717 1.8e-64 eag
COEIJKGJ_02718 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
COEIJKGJ_02719 1.3e-75 ykvE K transcriptional
COEIJKGJ_02720 2.5e-125 motB N Flagellar motor protein
COEIJKGJ_02721 1e-137 motA N flagellar motor
COEIJKGJ_02722 0.0 clpE O Belongs to the ClpA ClpB family
COEIJKGJ_02723 2.6e-178 ykvI S membrane
COEIJKGJ_02724 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
COEIJKGJ_02725 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
COEIJKGJ_02726 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
COEIJKGJ_02727 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
COEIJKGJ_02728 2e-61 ykvN K Transcriptional regulator
COEIJKGJ_02729 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
COEIJKGJ_02730 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
COEIJKGJ_02731 3.5e-35 3.5.1.104 M LysM domain
COEIJKGJ_02732 1.4e-162 G Glycosyl hydrolases family 18
COEIJKGJ_02733 5.6e-46 ykvR S Protein of unknown function (DUF3219)
COEIJKGJ_02734 6e-25 ykvS S protein conserved in bacteria
COEIJKGJ_02735 2.8e-28
COEIJKGJ_02736 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
COEIJKGJ_02737 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COEIJKGJ_02738 1.6e-88 stoA CO thiol-disulfide
COEIJKGJ_02739 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
COEIJKGJ_02740 2.3e-09
COEIJKGJ_02741 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
COEIJKGJ_02742 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
COEIJKGJ_02744 2.2e-127 glcT K antiterminator
COEIJKGJ_02745 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEIJKGJ_02746 2.1e-39 ptsH G phosphocarrier protein HPr
COEIJKGJ_02747 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COEIJKGJ_02748 7.2e-39 splA S Transcriptional regulator
COEIJKGJ_02749 7.5e-202 splB 4.1.99.14 L Spore photoproduct lyase
COEIJKGJ_02750 4.9e-128 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COEIJKGJ_02751 1.6e-261 mcpC NT chemotaxis protein
COEIJKGJ_02752 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
COEIJKGJ_02753 8e-124 ykwD J protein with SCP PR1 domains
COEIJKGJ_02754 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
COEIJKGJ_02755 0.0 pilS 2.7.13.3 T Histidine kinase
COEIJKGJ_02756 8e-224 patA 2.6.1.1 E Aminotransferase
COEIJKGJ_02757 2.2e-15
COEIJKGJ_02758 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
COEIJKGJ_02759 1.7e-84 ykyB S YkyB-like protein
COEIJKGJ_02760 3.8e-207 ykuC EGP Major facilitator Superfamily
COEIJKGJ_02761 1.5e-86 ykuD S protein conserved in bacteria
COEIJKGJ_02762 1.6e-165 ykuE S Metallophosphoesterase
COEIJKGJ_02763 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_02764 5.2e-234 ykuI T Diguanylate phosphodiesterase
COEIJKGJ_02765 3.9e-37 ykuJ S protein conserved in bacteria
COEIJKGJ_02766 4.4e-94 ykuK S Ribonuclease H-like
COEIJKGJ_02767 3.9e-27 ykzF S Antirepressor AbbA
COEIJKGJ_02768 1.6e-76 ykuL S CBS domain
COEIJKGJ_02769 3.5e-168 ccpC K Transcriptional regulator
COEIJKGJ_02770 8.5e-84 fld C Flavodoxin domain
COEIJKGJ_02771 3e-175 ykuO
COEIJKGJ_02772 3.9e-78 fld C Flavodoxin
COEIJKGJ_02773 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COEIJKGJ_02774 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COEIJKGJ_02775 9e-37 ykuS S Belongs to the UPF0180 family
COEIJKGJ_02776 8.8e-142 ykuT M Mechanosensitive ion channel
COEIJKGJ_02777 3.9e-101 ykuU O Alkyl hydroperoxide reductase
COEIJKGJ_02778 7e-80 ykuV CO thiol-disulfide
COEIJKGJ_02779 5.8e-95 rok K Repressor of ComK
COEIJKGJ_02780 4.2e-146 yknT
COEIJKGJ_02781 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
COEIJKGJ_02782 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
COEIJKGJ_02783 8.1e-246 moeA 2.10.1.1 H molybdopterin
COEIJKGJ_02784 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
COEIJKGJ_02785 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
COEIJKGJ_02786 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
COEIJKGJ_02787 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
COEIJKGJ_02788 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
COEIJKGJ_02789 1e-117 yknW S Yip1 domain
COEIJKGJ_02790 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
COEIJKGJ_02791 2.5e-124 macB V ABC transporter, ATP-binding protein
COEIJKGJ_02792 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
COEIJKGJ_02793 3.1e-136 fruR K Transcriptional regulator
COEIJKGJ_02794 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
COEIJKGJ_02795 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
COEIJKGJ_02796 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
COEIJKGJ_02797 8.1e-39 ykoA
COEIJKGJ_02798 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
COEIJKGJ_02799 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COEIJKGJ_02800 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
COEIJKGJ_02801 1.1e-12 S Uncharacterized protein YkpC
COEIJKGJ_02802 7.7e-183 mreB D Rod-share determining protein MreBH
COEIJKGJ_02803 1.5e-43 abrB K of stationary sporulation gene expression
COEIJKGJ_02804 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
COEIJKGJ_02805 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
COEIJKGJ_02806 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
COEIJKGJ_02807 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
COEIJKGJ_02808 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COEIJKGJ_02809 8.2e-31 ykzG S Belongs to the UPF0356 family
COEIJKGJ_02810 1.4e-147 ykrA S hydrolases of the HAD superfamily
COEIJKGJ_02811 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COEIJKGJ_02813 2e-115 recN L Putative cell-wall binding lipoprotein
COEIJKGJ_02814 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
COEIJKGJ_02815 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
COEIJKGJ_02816 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COEIJKGJ_02817 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
COEIJKGJ_02818 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
COEIJKGJ_02819 3.5e-277 speA 4.1.1.19 E Arginine
COEIJKGJ_02820 1.6e-42 yktA S Belongs to the UPF0223 family
COEIJKGJ_02821 4.6e-117 yktB S Belongs to the UPF0637 family
COEIJKGJ_02822 7.1e-26 ykzI
COEIJKGJ_02823 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
COEIJKGJ_02824 2.2e-76 ykzC S Acetyltransferase (GNAT) family
COEIJKGJ_02825 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
COEIJKGJ_02826 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
COEIJKGJ_02827 0.0 ylaA
COEIJKGJ_02828 2.7e-42 ylaB
COEIJKGJ_02829 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_02830 7.1e-12 sigC S Putative zinc-finger
COEIJKGJ_02831 4.1e-38 ylaE
COEIJKGJ_02832 8.2e-22 S Family of unknown function (DUF5325)
COEIJKGJ_02833 0.0 typA T GTP-binding protein TypA
COEIJKGJ_02834 4.2e-47 ylaH S YlaH-like protein
COEIJKGJ_02835 2.5e-32 ylaI S protein conserved in bacteria
COEIJKGJ_02836 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
COEIJKGJ_02837 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
COEIJKGJ_02838 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
COEIJKGJ_02839 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
COEIJKGJ_02840 8.7e-44 ylaN S Belongs to the UPF0358 family
COEIJKGJ_02841 4.5e-214 ftsW D Belongs to the SEDS family
COEIJKGJ_02842 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
COEIJKGJ_02843 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
COEIJKGJ_02844 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
COEIJKGJ_02845 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
COEIJKGJ_02846 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
COEIJKGJ_02847 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
COEIJKGJ_02848 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
COEIJKGJ_02849 3.4e-166 ctaG S cytochrome c oxidase
COEIJKGJ_02850 7e-62 ylbA S YugN-like family
COEIJKGJ_02851 2.6e-74 ylbB T COG0517 FOG CBS domain
COEIJKGJ_02852 9.6e-200 ylbC S protein with SCP PR1 domains
COEIJKGJ_02853 4.1e-63 ylbD S Putative coat protein
COEIJKGJ_02854 2.5e-36 ylbE S YlbE-like protein
COEIJKGJ_02855 1.8e-75 ylbF S Belongs to the UPF0342 family
COEIJKGJ_02856 3.7e-38 ylbG S UPF0298 protein
COEIJKGJ_02857 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
COEIJKGJ_02858 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COEIJKGJ_02859 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
COEIJKGJ_02860 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
COEIJKGJ_02861 6.8e-187 ylbL T Belongs to the peptidase S16 family
COEIJKGJ_02862 4e-234 ylbM S Belongs to the UPF0348 family
COEIJKGJ_02864 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
COEIJKGJ_02865 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
COEIJKGJ_02866 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
COEIJKGJ_02867 1.5e-88 ylbP K n-acetyltransferase
COEIJKGJ_02868 6.1e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COEIJKGJ_02869 3.2e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
COEIJKGJ_02870 2.9e-78 mraZ K Belongs to the MraZ family
COEIJKGJ_02871 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COEIJKGJ_02872 3.7e-44 ftsL D Essential cell division protein
COEIJKGJ_02873 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
COEIJKGJ_02874 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
COEIJKGJ_02875 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COEIJKGJ_02876 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COEIJKGJ_02877 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COEIJKGJ_02878 5.7e-186 spoVE D Belongs to the SEDS family
COEIJKGJ_02879 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COEIJKGJ_02880 5.3e-167 murB 1.3.1.98 M cell wall formation
COEIJKGJ_02881 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COEIJKGJ_02882 4.1e-103 ylxW S protein conserved in bacteria
COEIJKGJ_02883 2.6e-90 ylxX S protein conserved in bacteria
COEIJKGJ_02884 2.8e-55 sbp S small basic protein
COEIJKGJ_02885 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COEIJKGJ_02886 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COEIJKGJ_02887 0.0 bpr O COG1404 Subtilisin-like serine proteases
COEIJKGJ_02888 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
COEIJKGJ_02889 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COEIJKGJ_02890 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COEIJKGJ_02891 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
COEIJKGJ_02892 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
COEIJKGJ_02893 2.4e-37 ylmC S sporulation protein
COEIJKGJ_02894 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
COEIJKGJ_02895 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
COEIJKGJ_02896 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COEIJKGJ_02897 1.6e-39 yggT S membrane
COEIJKGJ_02898 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
COEIJKGJ_02899 2.6e-67 divIVA D Cell division initiation protein
COEIJKGJ_02900 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COEIJKGJ_02901 1.3e-63 dksA T COG1734 DnaK suppressor protein
COEIJKGJ_02902 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COEIJKGJ_02903 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COEIJKGJ_02904 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COEIJKGJ_02905 2.6e-231 pyrP F Xanthine uracil
COEIJKGJ_02906 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COEIJKGJ_02907 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COEIJKGJ_02908 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COEIJKGJ_02909 0.0 carB 6.3.5.5 F Belongs to the CarB family
COEIJKGJ_02910 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
COEIJKGJ_02911 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COEIJKGJ_02912 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COEIJKGJ_02913 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COEIJKGJ_02915 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
COEIJKGJ_02916 1.2e-178 cysP P phosphate transporter
COEIJKGJ_02917 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
COEIJKGJ_02918 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
COEIJKGJ_02919 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
COEIJKGJ_02920 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
COEIJKGJ_02921 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
COEIJKGJ_02922 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
COEIJKGJ_02923 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
COEIJKGJ_02924 3.1e-156 yloC S stress-induced protein
COEIJKGJ_02925 1.5e-40 ylzA S Belongs to the UPF0296 family
COEIJKGJ_02926 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
COEIJKGJ_02927 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COEIJKGJ_02928 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COEIJKGJ_02929 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COEIJKGJ_02930 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COEIJKGJ_02931 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COEIJKGJ_02932 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COEIJKGJ_02933 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
COEIJKGJ_02934 1.6e-140 stp 3.1.3.16 T phosphatase
COEIJKGJ_02935 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
COEIJKGJ_02936 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COEIJKGJ_02937 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COEIJKGJ_02938 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
COEIJKGJ_02939 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COEIJKGJ_02940 5.5e-59 asp S protein conserved in bacteria
COEIJKGJ_02941 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
COEIJKGJ_02942 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
COEIJKGJ_02943 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
COEIJKGJ_02944 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COEIJKGJ_02945 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
COEIJKGJ_02946 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COEIJKGJ_02947 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
COEIJKGJ_02948 1.1e-127 IQ reductase
COEIJKGJ_02949 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COEIJKGJ_02950 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COEIJKGJ_02951 0.0 smc D Required for chromosome condensation and partitioning
COEIJKGJ_02952 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COEIJKGJ_02953 3.5e-85
COEIJKGJ_02954 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COEIJKGJ_02955 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COEIJKGJ_02956 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COEIJKGJ_02957 4.5e-36 ylqC S Belongs to the UPF0109 family
COEIJKGJ_02958 6.3e-61 ylqD S YlqD protein
COEIJKGJ_02959 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COEIJKGJ_02960 7.8e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COEIJKGJ_02961 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COEIJKGJ_02962 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COEIJKGJ_02963 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COEIJKGJ_02964 4.3e-287 ylqG
COEIJKGJ_02965 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
COEIJKGJ_02966 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
COEIJKGJ_02967 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
COEIJKGJ_02968 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
COEIJKGJ_02969 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COEIJKGJ_02970 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
COEIJKGJ_02971 2.5e-169 xerC L tyrosine recombinase XerC
COEIJKGJ_02972 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COEIJKGJ_02973 4.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COEIJKGJ_02974 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
COEIJKGJ_02975 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
COEIJKGJ_02976 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
COEIJKGJ_02977 1.9e-31 fliE N Flagellar hook-basal body
COEIJKGJ_02978 1.6e-254 fliF N The M ring may be actively involved in energy transduction
COEIJKGJ_02979 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
COEIJKGJ_02980 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
COEIJKGJ_02981 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
COEIJKGJ_02982 1.5e-69 fliJ N Flagellar biosynthesis chaperone
COEIJKGJ_02983 2.2e-36 ylxF S MgtE intracellular N domain
COEIJKGJ_02984 5.1e-220 fliK N Flagellar hook-length control protein
COEIJKGJ_02985 2.3e-72 flgD N Flagellar basal body rod modification protein
COEIJKGJ_02986 8.2e-140 flgG N Flagellar basal body rod
COEIJKGJ_02987 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
COEIJKGJ_02988 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
COEIJKGJ_02989 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
COEIJKGJ_02990 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
COEIJKGJ_02991 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
COEIJKGJ_02992 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
COEIJKGJ_02993 3.6e-132 fliR N Flagellar biosynthetic protein FliR
COEIJKGJ_02994 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
COEIJKGJ_02995 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
COEIJKGJ_02996 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
COEIJKGJ_02997 4.1e-156 flhG D Belongs to the ParA family
COEIJKGJ_02998 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
COEIJKGJ_02999 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
COEIJKGJ_03000 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
COEIJKGJ_03001 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
COEIJKGJ_03002 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
COEIJKGJ_03003 9.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COEIJKGJ_03004 3.1e-76 ylxL
COEIJKGJ_03005 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
COEIJKGJ_03006 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COEIJKGJ_03007 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COEIJKGJ_03008 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COEIJKGJ_03009 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COEIJKGJ_03010 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
COEIJKGJ_03011 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
COEIJKGJ_03012 7.7e-233 rasP M zinc metalloprotease
COEIJKGJ_03013 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COEIJKGJ_03014 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COEIJKGJ_03015 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
COEIJKGJ_03016 1.1e-203 nusA K Participates in both transcription termination and antitermination
COEIJKGJ_03017 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
COEIJKGJ_03018 3.1e-47 ylxQ J ribosomal protein
COEIJKGJ_03019 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COEIJKGJ_03020 3e-44 ylxP S protein conserved in bacteria
COEIJKGJ_03021 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COEIJKGJ_03022 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COEIJKGJ_03023 1.1e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COEIJKGJ_03024 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COEIJKGJ_03025 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
COEIJKGJ_03026 6.1e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
COEIJKGJ_03027 4.4e-233 pepR S Belongs to the peptidase M16 family
COEIJKGJ_03028 2.6e-42 ymxH S YlmC YmxH family
COEIJKGJ_03029 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
COEIJKGJ_03030 6.3e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
COEIJKGJ_03031 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COEIJKGJ_03032 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
COEIJKGJ_03033 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COEIJKGJ_03034 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COEIJKGJ_03035 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
COEIJKGJ_03036 4.4e-32 S YlzJ-like protein
COEIJKGJ_03037 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
COEIJKGJ_03038 1.4e-133 ymfC K Transcriptional regulator
COEIJKGJ_03039 3.8e-205 ymfD EGP Major facilitator Superfamily
COEIJKGJ_03040 2e-233 ymfF S Peptidase M16
COEIJKGJ_03041 1.4e-242 ymfH S zinc protease
COEIJKGJ_03042 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
COEIJKGJ_03043 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
COEIJKGJ_03044 2.7e-143 ymfK S Protein of unknown function (DUF3388)
COEIJKGJ_03045 7.3e-116 ymfM S protein conserved in bacteria
COEIJKGJ_03046 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COEIJKGJ_03047 1.3e-235 cinA 3.5.1.42 S Belongs to the CinA family
COEIJKGJ_03048 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COEIJKGJ_03049 1e-215 pbpX V Beta-lactamase
COEIJKGJ_03050 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
COEIJKGJ_03051 1.9e-152 ymdB S protein conserved in bacteria
COEIJKGJ_03052 1.2e-36 spoVS S Stage V sporulation protein S
COEIJKGJ_03053 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
COEIJKGJ_03054 3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
COEIJKGJ_03055 1.9e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
COEIJKGJ_03056 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
COEIJKGJ_03057 2.2e-88 cotE S Spore coat protein
COEIJKGJ_03058 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COEIJKGJ_03059 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COEIJKGJ_03060 2.5e-69 S Regulatory protein YrvL
COEIJKGJ_03062 1.2e-97 ymcC S Membrane
COEIJKGJ_03063 4.4e-109 pksA K Transcriptional regulator
COEIJKGJ_03064 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
COEIJKGJ_03065 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
COEIJKGJ_03066 2.4e-186 pksD Q Acyl transferase domain
COEIJKGJ_03067 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
COEIJKGJ_03068 1.4e-37 acpK IQ Phosphopantetheine attachment site
COEIJKGJ_03069 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COEIJKGJ_03070 1.3e-245 pksG 2.3.3.10 I synthase
COEIJKGJ_03071 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
COEIJKGJ_03072 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
COEIJKGJ_03073 0.0 rhiB IQ polyketide synthase
COEIJKGJ_03074 0.0 pfaA Q Polyketide synthase of type I
COEIJKGJ_03075 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
COEIJKGJ_03076 0.0 dhbF IQ polyketide synthase
COEIJKGJ_03077 0.0 pks13 HQ Beta-ketoacyl synthase
COEIJKGJ_03078 6.3e-232 cypA C Cytochrome P450
COEIJKGJ_03079 2e-61 ymzB
COEIJKGJ_03080 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
COEIJKGJ_03081 8.6e-251 aprX O Belongs to the peptidase S8 family
COEIJKGJ_03082 1.9e-07 K Transcriptional regulator
COEIJKGJ_03083 2.1e-126 ymaC S Replication protein
COEIJKGJ_03084 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
COEIJKGJ_03085 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
COEIJKGJ_03086 5.4e-50 ebrA P Small Multidrug Resistance protein
COEIJKGJ_03088 2.1e-46 ymaF S YmaF family
COEIJKGJ_03089 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COEIJKGJ_03090 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
COEIJKGJ_03091 8.2e-23
COEIJKGJ_03092 4.5e-22 ymzA
COEIJKGJ_03093 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
COEIJKGJ_03094 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COEIJKGJ_03095 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COEIJKGJ_03096 2e-109 ymaB
COEIJKGJ_03097 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COEIJKGJ_03098 1.7e-176 spoVK O stage V sporulation protein K
COEIJKGJ_03099 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COEIJKGJ_03100 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
COEIJKGJ_03101 1.1e-68 glnR K transcriptional
COEIJKGJ_03102 7e-261 glnA 6.3.1.2 E glutamine synthetase
COEIJKGJ_03103 1.1e-09
COEIJKGJ_03104 1.6e-31
COEIJKGJ_03105 2.1e-16
COEIJKGJ_03106 8.9e-90 G SMI1-KNR4 cell-wall
COEIJKGJ_03107 3.1e-113 ynaC
COEIJKGJ_03108 4.1e-11 S Protein of unknown function (DUF1433)
COEIJKGJ_03109 2e-97 ynaD J Acetyltransferase (GNAT) domain
COEIJKGJ_03110 4.1e-73 S CAAX protease self-immunity
COEIJKGJ_03111 4.7e-08 S Uncharacterised protein family (UPF0715)
COEIJKGJ_03112 5.5e-20 K Cro/C1-type HTH DNA-binding domain
COEIJKGJ_03113 2.1e-117 ynaE S Domain of unknown function (DUF3885)
COEIJKGJ_03114 8.6e-15 ynaF
COEIJKGJ_03116 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
COEIJKGJ_03117 7.9e-255 xynT G MFS/sugar transport protein
COEIJKGJ_03118 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
COEIJKGJ_03119 6.8e-212 xylR GK ROK family
COEIJKGJ_03120 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
COEIJKGJ_03121 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
COEIJKGJ_03122 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
COEIJKGJ_03123 1.4e-254 iolT EGP Major facilitator Superfamily
COEIJKGJ_03124 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COEIJKGJ_03126 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
COEIJKGJ_03127 5.2e-15
COEIJKGJ_03130 2.1e-162 S Thymidylate synthase
COEIJKGJ_03132 1.7e-48 S Domain of unknown function, YrpD
COEIJKGJ_03133 1.1e-69 S Domain of unknown function, YrpD
COEIJKGJ_03136 7.9e-25 tatA U protein secretion
COEIJKGJ_03137 1.8e-71
COEIJKGJ_03138 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
COEIJKGJ_03141 2.8e-52 gerAA EG Spore germination protein
COEIJKGJ_03142 1.8e-146 gerAA EG Spore germination protein
COEIJKGJ_03143 3.4e-88 gerLC S Spore germination protein
COEIJKGJ_03144 7.7e-154 yndG S DoxX-like family
COEIJKGJ_03145 2.6e-117 yndH S Domain of unknown function (DUF4166)
COEIJKGJ_03146 0.0 yndJ S YndJ-like protein
COEIJKGJ_03148 8.6e-139 yndL S Replication protein
COEIJKGJ_03149 5.8e-74 yndM S Protein of unknown function (DUF2512)
COEIJKGJ_03150 1.3e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
COEIJKGJ_03151 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COEIJKGJ_03152 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
COEIJKGJ_03153 5e-111 yneB L resolvase
COEIJKGJ_03154 1.3e-32 ynzC S UPF0291 protein
COEIJKGJ_03155 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COEIJKGJ_03156 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
COEIJKGJ_03157 1.8e-28 yneF S UPF0154 protein
COEIJKGJ_03158 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
COEIJKGJ_03159 7.1e-127 ccdA O cytochrome c biogenesis protein
COEIJKGJ_03160 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
COEIJKGJ_03161 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
COEIJKGJ_03162 4.2e-74 yneK S Protein of unknown function (DUF2621)
COEIJKGJ_03163 1.2e-64 hspX O Spore coat protein
COEIJKGJ_03164 3.9e-19 sspP S Belongs to the SspP family
COEIJKGJ_03165 2.2e-14 sspO S Belongs to the SspO family
COEIJKGJ_03166 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
COEIJKGJ_03167 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
COEIJKGJ_03169 3.1e-08 sspN S Small acid-soluble spore protein N family
COEIJKGJ_03170 3.9e-35 tlp S Belongs to the Tlp family
COEIJKGJ_03171 2e-73 yneP S Thioesterase-like superfamily
COEIJKGJ_03172 1.7e-53 yneQ
COEIJKGJ_03173 4.1e-49 yneR S Belongs to the HesB IscA family
COEIJKGJ_03174 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COEIJKGJ_03175 8.6e-69 yccU S CoA-binding protein
COEIJKGJ_03176 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COEIJKGJ_03177 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COEIJKGJ_03178 2.3e-12
COEIJKGJ_03179 1.3e-57 ynfC
COEIJKGJ_03180 1.8e-251 agcS E Sodium alanine symporter
COEIJKGJ_03181 1.7e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
COEIJKGJ_03183 1.2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
COEIJKGJ_03184 2.4e-297 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
COEIJKGJ_03185 1.6e-79 yngA S membrane
COEIJKGJ_03186 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COEIJKGJ_03187 5.5e-104 yngC S membrane-associated protein
COEIJKGJ_03188 2.6e-230 nrnB S phosphohydrolase (DHH superfamily)
COEIJKGJ_03189 1.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
COEIJKGJ_03190 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
COEIJKGJ_03191 2.9e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
COEIJKGJ_03192 2.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
COEIJKGJ_03193 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
COEIJKGJ_03194 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
COEIJKGJ_03195 1.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
COEIJKGJ_03196 5e-303 yngK T Glycosyl hydrolase-like 10
COEIJKGJ_03197 4e-63 yngL S Protein of unknown function (DUF1360)
COEIJKGJ_03198 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
COEIJKGJ_03199 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_03202 6.1e-157 ydhU P Catalase
COEIJKGJ_03203 9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
COEIJKGJ_03204 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
COEIJKGJ_03205 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
COEIJKGJ_03206 7.4e-132 ydhQ K UTRA
COEIJKGJ_03207 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COEIJKGJ_03208 9.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COEIJKGJ_03209 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
COEIJKGJ_03210 4.2e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
COEIJKGJ_03211 4.6e-200 pbuE EGP Major facilitator Superfamily
COEIJKGJ_03212 2.5e-98 ydhK M Protein of unknown function (DUF1541)
COEIJKGJ_03213 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COEIJKGJ_03214 1.5e-80 K Acetyltransferase (GNAT) domain
COEIJKGJ_03216 8.7e-68 frataxin S Domain of unknown function (DU1801)
COEIJKGJ_03217 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
COEIJKGJ_03218 4.2e-127
COEIJKGJ_03219 2.9e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
COEIJKGJ_03220 6.3e-243 ydhD M Glycosyl hydrolase
COEIJKGJ_03221 6.5e-122 ydhC K FCD
COEIJKGJ_03222 1.6e-121 ydhB S membrane transporter protein
COEIJKGJ_03223 4.8e-208 tcaB EGP Major facilitator Superfamily
COEIJKGJ_03224 2.4e-69 ydgJ K Winged helix DNA-binding domain
COEIJKGJ_03225 8.8e-113 drgA C nitroreductase
COEIJKGJ_03226 0.0 ydgH S drug exporters of the RND superfamily
COEIJKGJ_03227 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
COEIJKGJ_03228 2.3e-90 dinB S DinB family
COEIJKGJ_03229 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
COEIJKGJ_03230 1.7e-301 expZ S ABC transporter
COEIJKGJ_03231 4.4e-104 G Xylose isomerase-like TIM barrel
COEIJKGJ_03232 1e-190 csbC EGP Major facilitator Superfamily
COEIJKGJ_03233 2e-119 purR K helix_turn _helix lactose operon repressor
COEIJKGJ_03234 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
COEIJKGJ_03235 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
COEIJKGJ_03236 1.6e-52 S DoxX-like family
COEIJKGJ_03237 3e-94 K Bacterial regulatory proteins, tetR family
COEIJKGJ_03238 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
COEIJKGJ_03239 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
COEIJKGJ_03240 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
COEIJKGJ_03241 5.2e-122 ydfS S Protein of unknown function (DUF421)
COEIJKGJ_03242 4.4e-118 ydfR S Protein of unknown function (DUF421)
COEIJKGJ_03244 6.3e-29
COEIJKGJ_03245 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
COEIJKGJ_03246 1.3e-57 traF CO Thioredoxin
COEIJKGJ_03247 8.8e-63 mhqP S DoxX
COEIJKGJ_03248 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
COEIJKGJ_03249 9.6e-112 ydfN C nitroreductase
COEIJKGJ_03250 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COEIJKGJ_03251 3.2e-147 K Bacterial transcription activator, effector binding domain
COEIJKGJ_03252 5.9e-118 S Protein of unknown function (DUF554)
COEIJKGJ_03253 1.9e-177 S Alpha/beta hydrolase family
COEIJKGJ_03254 0.0 ydfJ S drug exporters of the RND superfamily
COEIJKGJ_03255 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
COEIJKGJ_03256 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
COEIJKGJ_03258 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
COEIJKGJ_03259 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
COEIJKGJ_03260 3.8e-116 ydfE S Flavin reductase like domain
COEIJKGJ_03261 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COEIJKGJ_03262 1e-162 ydfC EG EamA-like transporter family
COEIJKGJ_03263 7.2e-149 ydfB J GNAT acetyltransferase
COEIJKGJ_03264 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
COEIJKGJ_03265 1.8e-56 arsR K transcriptional
COEIJKGJ_03266 2.5e-104 ydeS K Transcriptional regulator
COEIJKGJ_03267 1.5e-185 ydeR EGP Major facilitator Superfamily
COEIJKGJ_03268 1.7e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
COEIJKGJ_03269 1.8e-68 ydeP K Transcriptional regulator
COEIJKGJ_03270 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
COEIJKGJ_03271 5.7e-55 K HxlR-like helix-turn-helix
COEIJKGJ_03272 1.8e-104 ydeN S Serine hydrolase
COEIJKGJ_03273 1.3e-72 maoC I N-terminal half of MaoC dehydratase
COEIJKGJ_03274 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COEIJKGJ_03275 2e-152 ydeK EG -transporter
COEIJKGJ_03276 3.4e-84 K Transcriptional regulator C-terminal region
COEIJKGJ_03277 1.8e-14 ptsH G PTS HPr component phosphorylation site
COEIJKGJ_03278 1.1e-31 S SNARE associated Golgi protein
COEIJKGJ_03279 1.3e-109
COEIJKGJ_03280 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
COEIJKGJ_03281 2.7e-45 ydeH
COEIJKGJ_03282 1.8e-216 ydeG EGP Major facilitator superfamily
COEIJKGJ_03283 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COEIJKGJ_03284 1.4e-164 ydeE K AraC family transcriptional regulator
COEIJKGJ_03285 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
COEIJKGJ_03286 1.4e-164 rhaS5 K AraC-like ligand binding domain
COEIJKGJ_03287 2.2e-15 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
COEIJKGJ_03288 1.3e-106 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
COEIJKGJ_03289 1.5e-77 carD K Transcription factor
COEIJKGJ_03290 8.7e-30 cspL K Cold shock
COEIJKGJ_03291 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
COEIJKGJ_03295 9.6e-40
COEIJKGJ_03296 1.7e-32 K Helix-turn-helix XRE-family like proteins
COEIJKGJ_03297 3.3e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
COEIJKGJ_03298 8.5e-45
COEIJKGJ_03299 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
COEIJKGJ_03300 4.6e-107 K Transcriptional regulator
COEIJKGJ_03301 3.2e-114 yecA E amino acid
COEIJKGJ_03309 2.6e-82 ydcK S Belongs to the SprT family
COEIJKGJ_03310 0.0 yhgF K COG2183 Transcriptional accessory protein
COEIJKGJ_03311 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
COEIJKGJ_03312 1.1e-136 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
COEIJKGJ_03313 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
COEIJKGJ_03314 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
COEIJKGJ_03315 9.3e-189 rsbU 3.1.3.3 KT phosphatase
COEIJKGJ_03316 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
COEIJKGJ_03317 5.2e-57 rsbS T antagonist
COEIJKGJ_03318 3.7e-143 rsbR T Positive regulator of sigma-B
COEIJKGJ_03319 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
COEIJKGJ_03320 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
COEIJKGJ_03321 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COEIJKGJ_03322 5.5e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
COEIJKGJ_03323 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COEIJKGJ_03324 1.2e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
COEIJKGJ_03325 3.9e-260 ydbT S Membrane
COEIJKGJ_03326 2.1e-82 ydbS S Bacterial PH domain
COEIJKGJ_03327 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COEIJKGJ_03328 5.3e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COEIJKGJ_03329 3.3e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COEIJKGJ_03330 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
COEIJKGJ_03331 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COEIJKGJ_03332 2.2e-07 S Fur-regulated basic protein A
COEIJKGJ_03333 1.1e-18 S Fur-regulated basic protein B
COEIJKGJ_03334 3.4e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
COEIJKGJ_03335 2.7e-52 ydbL
COEIJKGJ_03336 1.6e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
COEIJKGJ_03337 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
COEIJKGJ_03338 9.7e-181 ydbI S AI-2E family transporter
COEIJKGJ_03339 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COEIJKGJ_03340 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
COEIJKGJ_03341 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
COEIJKGJ_03342 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
COEIJKGJ_03343 3.5e-154 ydbD P Catalase
COEIJKGJ_03344 3.1e-62 ydbC S Domain of unknown function (DUF4937
COEIJKGJ_03345 8.9e-59 ydbB G Cupin domain
COEIJKGJ_03347 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
COEIJKGJ_03348 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
COEIJKGJ_03350 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
COEIJKGJ_03351 2.1e-39
COEIJKGJ_03352 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COEIJKGJ_03353 1.9e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
COEIJKGJ_03354 0.0 ydaO E amino acid
COEIJKGJ_03355 0.0 ydaN S Bacterial cellulose synthase subunit
COEIJKGJ_03356 4.5e-233 ydaM M Glycosyl transferase family group 2
COEIJKGJ_03357 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
COEIJKGJ_03358 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
COEIJKGJ_03359 7.4e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
COEIJKGJ_03360 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COEIJKGJ_03361 2.5e-74 lrpC K Transcriptional regulator
COEIJKGJ_03362 3.3e-46 ydzA EGP Major facilitator Superfamily
COEIJKGJ_03363 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
COEIJKGJ_03364 6.8e-77 ydaG 1.4.3.5 S general stress protein
COEIJKGJ_03365 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
COEIJKGJ_03366 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
COEIJKGJ_03367 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_03368 9e-99 ydaC Q Methyltransferase domain
COEIJKGJ_03369 2.1e-293 ydaB IQ acyl-CoA ligase
COEIJKGJ_03370 0.0 mtlR K transcriptional regulator, MtlR
COEIJKGJ_03371 2.4e-172 ydhF S Oxidoreductase
COEIJKGJ_03372 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
COEIJKGJ_03373 1.4e-49 yczJ S biosynthesis
COEIJKGJ_03375 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
COEIJKGJ_03376 1.2e-132 kipR K Transcriptional regulator
COEIJKGJ_03377 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
COEIJKGJ_03378 1.2e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
COEIJKGJ_03379 2.8e-148 ycsI S Belongs to the D-glutamate cyclase family
COEIJKGJ_03380 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
COEIJKGJ_03381 2.7e-140 ycsF S Belongs to the UPF0271 (lamB) family
COEIJKGJ_03382 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
COEIJKGJ_03384 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
COEIJKGJ_03385 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
COEIJKGJ_03386 1.3e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
COEIJKGJ_03387 4.1e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
COEIJKGJ_03388 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
COEIJKGJ_03389 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
COEIJKGJ_03390 4.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
COEIJKGJ_03391 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
COEIJKGJ_03392 7.3e-56
COEIJKGJ_03393 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
COEIJKGJ_03394 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
COEIJKGJ_03395 2.9e-100 ycnI S protein conserved in bacteria
COEIJKGJ_03396 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_03397 1.8e-148 glcU U Glucose uptake
COEIJKGJ_03398 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COEIJKGJ_03399 2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COEIJKGJ_03400 5.6e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
COEIJKGJ_03401 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
COEIJKGJ_03402 1.6e-45 ycnE S Monooxygenase
COEIJKGJ_03403 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
COEIJKGJ_03404 7.9e-152 ycnC K Transcriptional regulator
COEIJKGJ_03405 1.4e-251 ycnB EGP Major facilitator Superfamily
COEIJKGJ_03406 1.4e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
COEIJKGJ_03407 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
COEIJKGJ_03408 1.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_03409 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_03410 5.7e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
COEIJKGJ_03413 2e-70 S aspartate phosphatase
COEIJKGJ_03414 5.2e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
COEIJKGJ_03415 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_03416 1.1e-195 yclI V ABC transporter (permease) YclI
COEIJKGJ_03417 5.6e-121 yclH P ABC transporter
COEIJKGJ_03418 1e-196 gerKB F Spore germination protein
COEIJKGJ_03419 8e-227 gerKC S spore germination
COEIJKGJ_03420 1.9e-276 gerKA EG Spore germination protein
COEIJKGJ_03422 5.9e-292 yclG M Pectate lyase superfamily protein
COEIJKGJ_03423 7.3e-267 dtpT E amino acid peptide transporter
COEIJKGJ_03424 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
COEIJKGJ_03425 2.3e-81 yclD
COEIJKGJ_03426 4e-39 bsdD 4.1.1.61 S response to toxic substance
COEIJKGJ_03427 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
COEIJKGJ_03428 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
COEIJKGJ_03429 4.9e-162 bsdA K LysR substrate binding domain
COEIJKGJ_03430 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
COEIJKGJ_03431 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
COEIJKGJ_03432 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
COEIJKGJ_03433 1.7e-114 yczE S membrane
COEIJKGJ_03434 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
COEIJKGJ_03435 5.6e-250 ycxD K GntR family transcriptional regulator
COEIJKGJ_03436 6.4e-160 ycxC EG EamA-like transporter family
COEIJKGJ_03437 2.3e-88 S YcxB-like protein
COEIJKGJ_03438 6.1e-227 EGP Major Facilitator Superfamily
COEIJKGJ_03439 6.4e-139 srfAD Q thioesterase
COEIJKGJ_03440 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
COEIJKGJ_03441 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_03442 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COEIJKGJ_03443 1.3e-63 hxlR K transcriptional
COEIJKGJ_03444 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
COEIJKGJ_03445 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
COEIJKGJ_03446 1.9e-186 tlpC 2.7.13.3 NT chemotaxis protein
COEIJKGJ_03447 3e-70 nucA M Deoxyribonuclease NucA/NucB
COEIJKGJ_03448 6.5e-69 nin S Competence protein J (ComJ)
COEIJKGJ_03449 8e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COEIJKGJ_03450 7.8e-52 yckD S Protein of unknown function (DUF2680)
COEIJKGJ_03451 6.2e-76 yckC S membrane
COEIJKGJ_03454 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
COEIJKGJ_03455 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
COEIJKGJ_03456 4.6e-227 yciC S GTPases (G3E family)
COEIJKGJ_03457 5.5e-109 yciB M ErfK YbiS YcfS YnhG
COEIJKGJ_03458 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
COEIJKGJ_03459 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
COEIJKGJ_03460 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
COEIJKGJ_03461 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
COEIJKGJ_03462 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
COEIJKGJ_03463 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
COEIJKGJ_03464 3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
COEIJKGJ_03465 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
COEIJKGJ_03466 1.6e-157 I alpha/beta hydrolase fold
COEIJKGJ_03467 9.1e-140 ycgR S permeases
COEIJKGJ_03468 9.1e-145 ycgQ S membrane
COEIJKGJ_03469 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
COEIJKGJ_03470 2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COEIJKGJ_03471 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
COEIJKGJ_03472 5.1e-170 ycgM E Proline dehydrogenase
COEIJKGJ_03473 4.1e-144 ycgL S Predicted nucleotidyltransferase
COEIJKGJ_03474 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
COEIJKGJ_03475 1.2e-177 oxyR3 K LysR substrate binding domain
COEIJKGJ_03476 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
COEIJKGJ_03477 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COEIJKGJ_03478 2.5e-109 tmrB S AAA domain
COEIJKGJ_03479 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COEIJKGJ_03480 2.4e-112 ycgI S Domain of unknown function (DUF1989)
COEIJKGJ_03481 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
COEIJKGJ_03482 7.6e-151 yqcI S YqcI/YcgG family
COEIJKGJ_03483 2e-112 ycgF E Lysine exporter protein LysE YggA
COEIJKGJ_03484 2.9e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
COEIJKGJ_03485 1.8e-260 mdr EGP Major facilitator Superfamily
COEIJKGJ_03486 3e-290 lctP C L-lactate permease
COEIJKGJ_03487 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COEIJKGJ_03488 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
COEIJKGJ_03489 4.1e-81 ycgB
COEIJKGJ_03490 1.1e-256 ycgA S Membrane
COEIJKGJ_03491 1.9e-217 amhX S amidohydrolase
COEIJKGJ_03492 1.5e-163 opuAC E glycine betaine
COEIJKGJ_03493 1.3e-127 opuAB P glycine betaine
COEIJKGJ_03494 5.1e-229 proV 3.6.3.32 E glycine betaine
COEIJKGJ_03495 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
COEIJKGJ_03496 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
COEIJKGJ_03497 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
COEIJKGJ_03498 2e-192 yceH P Belongs to the TelA family
COEIJKGJ_03499 0.0 yceG S Putative component of 'biosynthetic module'
COEIJKGJ_03500 6.3e-137 terC P Protein of unknown function (DUF475)
COEIJKGJ_03501 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
COEIJKGJ_03502 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
COEIJKGJ_03503 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
COEIJKGJ_03504 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
COEIJKGJ_03505 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
COEIJKGJ_03506 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
COEIJKGJ_03507 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
COEIJKGJ_03508 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
COEIJKGJ_03509 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
COEIJKGJ_03510 6.1e-173 S response regulator aspartate phosphatase
COEIJKGJ_03511 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
COEIJKGJ_03512 1.5e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_03513 4.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_03514 6.6e-177 ycdA S Domain of unknown function (DUF5105)
COEIJKGJ_03515 1e-142 yccK C Aldo keto reductase
COEIJKGJ_03516 1.7e-22 yccK C Aldo keto reductase
COEIJKGJ_03517 2.7e-200 natB CP ABC-2 family transporter protein
COEIJKGJ_03518 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
COEIJKGJ_03519 1.2e-126 lytR_2 T LytTr DNA-binding domain
COEIJKGJ_03520 1.2e-156 2.7.13.3 T GHKL domain
COEIJKGJ_03521 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
COEIJKGJ_03522 4.9e-58 S RDD family
COEIJKGJ_03523 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
COEIJKGJ_03524 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
COEIJKGJ_03525 4.8e-102 yxaF K Transcriptional regulator
COEIJKGJ_03526 3e-225 lmrB EGP the major facilitator superfamily
COEIJKGJ_03527 2.9e-199 ycbU E Selenocysteine lyase
COEIJKGJ_03528 6.9e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
COEIJKGJ_03529 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COEIJKGJ_03530 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
COEIJKGJ_03531 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
COEIJKGJ_03532 3.6e-134 ycbR T vWA found in TerF C terminus
COEIJKGJ_03533 2.8e-78 sleB 3.5.1.28 M Cell wall
COEIJKGJ_03534 8.2e-53 ycbP S Protein of unknown function (DUF2512)
COEIJKGJ_03535 1.8e-114 S ABC-2 family transporter protein
COEIJKGJ_03536 3.5e-166 ycbN V ABC transporter, ATP-binding protein
COEIJKGJ_03537 4.2e-167 T PhoQ Sensor
COEIJKGJ_03538 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
COEIJKGJ_03539 5.4e-167 eamA1 EG spore germination
COEIJKGJ_03540 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
COEIJKGJ_03541 8.6e-167 ycbJ S Macrolide 2'-phosphotransferase
COEIJKGJ_03542 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
COEIJKGJ_03543 2.1e-123 ycbG K FCD
COEIJKGJ_03544 1.2e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
COEIJKGJ_03545 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
COEIJKGJ_03546 3.2e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COEIJKGJ_03547 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
COEIJKGJ_03548 2.6e-169 glnL T Regulator
COEIJKGJ_03549 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
COEIJKGJ_03550 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
COEIJKGJ_03551 2.8e-255 agcS E Sodium alanine symporter
COEIJKGJ_03552 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
COEIJKGJ_03553 1.4e-259 mmuP E amino acid
COEIJKGJ_03554 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
COEIJKGJ_03556 4.9e-128 K UTRA
COEIJKGJ_03557 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COEIJKGJ_03558 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEIJKGJ_03559 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COEIJKGJ_03560 3.3e-191 yceA S Belongs to the UPF0176 family
COEIJKGJ_03561 2e-45 ybfN
COEIJKGJ_03562 6.9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
COEIJKGJ_03563 2.7e-85 ybfM S SNARE associated Golgi protein
COEIJKGJ_03564 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COEIJKGJ_03565 1e-167 S Alpha/beta hydrolase family
COEIJKGJ_03567 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
COEIJKGJ_03568 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COEIJKGJ_03569 5.2e-145 msmR K AraC-like ligand binding domain
COEIJKGJ_03570 3.7e-160 ybfH EG EamA-like transporter family
COEIJKGJ_03571 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
COEIJKGJ_03573 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
COEIJKGJ_03574 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
COEIJKGJ_03575 2.9e-35 S Protein of unknown function (DUF2651)
COEIJKGJ_03576 7.3e-258 glpT G -transporter
COEIJKGJ_03577 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
COEIJKGJ_03578 8.8e-290 ybeC E amino acid
COEIJKGJ_03579 4.9e-41 ybyB
COEIJKGJ_03580 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
COEIJKGJ_03581 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
COEIJKGJ_03582 4.9e-30 ybxH S Family of unknown function (DUF5370)
COEIJKGJ_03583 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
COEIJKGJ_03584 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
COEIJKGJ_03585 1.5e-214 ybdO S Domain of unknown function (DUF4885)
COEIJKGJ_03586 8.5e-151 ybdN
COEIJKGJ_03587 3.9e-139 KLT Protein tyrosine kinase
COEIJKGJ_03589 1.8e-168 T His Kinase A (phospho-acceptor) domain
COEIJKGJ_03590 3.8e-122 T Transcriptional regulatory protein, C terminal
COEIJKGJ_03591 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
COEIJKGJ_03592 1.1e-77 txn CO Thioredoxin-like
COEIJKGJ_03593 7.8e-91 C HEAT repeats
COEIJKGJ_03594 4e-248 skfF S ABC transporter
COEIJKGJ_03595 1.9e-135 skfE V ABC transporter
COEIJKGJ_03596 1.6e-277 V CAAX protease self-immunity
COEIJKGJ_03597 9.1e-239 J 4Fe-4S single cluster domain
COEIJKGJ_03599 4.2e-201 ybcL EGP Major facilitator Superfamily
COEIJKGJ_03600 5.1e-50 ybzH K Helix-turn-helix domain
COEIJKGJ_03601 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
COEIJKGJ_03602 5.6e-46
COEIJKGJ_03604 4.7e-91 can 4.2.1.1 P carbonic anhydrase
COEIJKGJ_03605 0.0 ybcC S Belongs to the UPF0753 family
COEIJKGJ_03606 1.8e-276 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
COEIJKGJ_03607 1.2e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
COEIJKGJ_03608 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
COEIJKGJ_03609 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
COEIJKGJ_03610 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COEIJKGJ_03611 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COEIJKGJ_03612 1.5e-224 ybbR S protein conserved in bacteria
COEIJKGJ_03613 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COEIJKGJ_03614 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
COEIJKGJ_03615 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_03621 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
COEIJKGJ_03622 1.9e-86 ybbJ J acetyltransferase
COEIJKGJ_03623 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
COEIJKGJ_03624 2.1e-149 ybbH K transcriptional
COEIJKGJ_03625 1.4e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEIJKGJ_03626 4.2e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
COEIJKGJ_03627 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
COEIJKGJ_03628 4.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
COEIJKGJ_03629 5e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
COEIJKGJ_03630 1.4e-165 feuA P Iron-uptake system-binding protein
COEIJKGJ_03631 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_03632 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_03633 2.2e-142 ybbA S Putative esterase
COEIJKGJ_03634 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
COEIJKGJ_03636 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
COEIJKGJ_03637 3.3e-166 ygxA S Nucleotidyltransferase-like
COEIJKGJ_03638 1.1e-54 ygzB S UPF0295 protein
COEIJKGJ_03639 4e-80 perR P Belongs to the Fur family
COEIJKGJ_03640 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
COEIJKGJ_03641 1.2e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
COEIJKGJ_03642 8.7e-180 ygaE S Membrane
COEIJKGJ_03643 1.8e-301 ygaD V ABC transporter
COEIJKGJ_03644 1.3e-104 ygaC J Belongs to the UPF0374 family
COEIJKGJ_03645 1.5e-37 ygaB S YgaB-like protein
COEIJKGJ_03646 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
COEIJKGJ_03647 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
COEIJKGJ_03648 6.9e-36 yfhS
COEIJKGJ_03649 3.3e-210 mutY L A G-specific
COEIJKGJ_03650 1.2e-185 yfhP S membrane-bound metal-dependent
COEIJKGJ_03651 0.0 yfhO S Bacterial membrane protein YfhO
COEIJKGJ_03652 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
COEIJKGJ_03653 1.3e-170 yfhM S Alpha beta hydrolase
COEIJKGJ_03654 3.5e-51 yfhL S SdpI/YhfL protein family
COEIJKGJ_03655 2.4e-87 batE T Bacterial SH3 domain homologues
COEIJKGJ_03656 2.9e-44 yfhJ S WVELL protein
COEIJKGJ_03657 6.2e-20 sspK S reproduction
COEIJKGJ_03658 1.1e-209 yfhI EGP Major facilitator Superfamily
COEIJKGJ_03660 9.7e-52 yfhH S Protein of unknown function (DUF1811)
COEIJKGJ_03661 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
COEIJKGJ_03662 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
COEIJKGJ_03664 2.1e-25 yfhD S YfhD-like protein
COEIJKGJ_03665 1.5e-106 yfhC C nitroreductase
COEIJKGJ_03666 1.8e-167 yfhB 5.3.3.17 S PhzF family
COEIJKGJ_03667 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_03668 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_03669 1e-176 yfiY P ABC transporter substrate-binding protein
COEIJKGJ_03670 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COEIJKGJ_03671 5.8e-80 yfiV K transcriptional
COEIJKGJ_03672 3.4e-283 yfiU EGP Major facilitator Superfamily
COEIJKGJ_03673 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
COEIJKGJ_03674 1.5e-209 yfiS EGP Major facilitator Superfamily
COEIJKGJ_03675 7.1e-107 yfiR K Transcriptional regulator
COEIJKGJ_03676 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
COEIJKGJ_03677 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
COEIJKGJ_03678 8.3e-99 padR K transcriptional
COEIJKGJ_03679 2.6e-203 V COG0842 ABC-type multidrug transport system, permease component
COEIJKGJ_03680 2e-206 V ABC-2 family transporter protein
COEIJKGJ_03681 1.4e-170 V ABC transporter, ATP-binding protein
COEIJKGJ_03682 3.2e-113 KT LuxR family transcriptional regulator
COEIJKGJ_03683 1.1e-214 yxjM T Histidine kinase
COEIJKGJ_03685 1.1e-233 S Oxidoreductase
COEIJKGJ_03686 8.4e-184 G Xylose isomerase
COEIJKGJ_03687 1.8e-262 iolT EGP Major facilitator Superfamily
COEIJKGJ_03688 1.5e-177 K AraC-like ligand binding domain
COEIJKGJ_03689 5.7e-163 yfiE 1.13.11.2 S glyoxalase
COEIJKGJ_03690 6.4e-64 mhqP S DoxX
COEIJKGJ_03691 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
COEIJKGJ_03692 8.4e-307 yfiB3 V ABC transporter
COEIJKGJ_03693 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEIJKGJ_03694 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
COEIJKGJ_03695 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
COEIJKGJ_03696 7.4e-44 yfjA S Belongs to the WXG100 family
COEIJKGJ_03697 9.2e-191 yfjB
COEIJKGJ_03698 4.5e-143 yfjC
COEIJKGJ_03699 1.8e-101 yfjD S Family of unknown function (DUF5381)
COEIJKGJ_03700 1.1e-79 S Family of unknown function (DUF5381)
COEIJKGJ_03701 4e-56 yfjF S UPF0060 membrane protein
COEIJKGJ_03702 8.3e-24 sspH S Belongs to the SspH family
COEIJKGJ_03703 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
COEIJKGJ_03704 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
COEIJKGJ_03705 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COEIJKGJ_03706 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
COEIJKGJ_03707 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
COEIJKGJ_03708 1.1e-83 yfjM S Psort location Cytoplasmic, score
COEIJKGJ_03709 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COEIJKGJ_03710 1.6e-39 S YfzA-like protein
COEIJKGJ_03711 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COEIJKGJ_03712 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
COEIJKGJ_03713 1.7e-184 corA P Mediates influx of magnesium ions
COEIJKGJ_03714 9.8e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
COEIJKGJ_03715 1.7e-153 pdaA G deacetylase
COEIJKGJ_03716 1.1e-26 yfjT
COEIJKGJ_03717 5.4e-222 yfkA S YfkB-like domain
COEIJKGJ_03718 6e-149 yfkC M Mechanosensitive ion channel
COEIJKGJ_03719 1.2e-146 yfkD S YfkD-like protein
COEIJKGJ_03720 1.8e-182 cax P COG0387 Ca2 H antiporter
COEIJKGJ_03721 2.6e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
COEIJKGJ_03722 5e-08
COEIJKGJ_03723 4.8e-143 yihY S Belongs to the UPF0761 family
COEIJKGJ_03724 1.2e-49 yfkI S gas vesicle protein
COEIJKGJ_03725 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COEIJKGJ_03726 1.3e-28 yfkK S Belongs to the UPF0435 family
COEIJKGJ_03727 6.8e-207 ydiM EGP Major facilitator Superfamily
COEIJKGJ_03728 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
COEIJKGJ_03729 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
COEIJKGJ_03730 1.8e-124 yfkO C nitroreductase
COEIJKGJ_03731 5.1e-133 treR K transcriptional
COEIJKGJ_03732 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
COEIJKGJ_03733 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
COEIJKGJ_03734 1.9e-24 yfkQ EG Spore germination protein
COEIJKGJ_03735 3.1e-251 agcS_1 E Sodium alanine symporter
COEIJKGJ_03736 6e-67 yhdN S Domain of unknown function (DUF1992)
COEIJKGJ_03737 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
COEIJKGJ_03738 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
COEIJKGJ_03739 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
COEIJKGJ_03740 5.3e-50 yflH S Protein of unknown function (DUF3243)
COEIJKGJ_03741 4.1e-19 yflI
COEIJKGJ_03742 4e-18 yflJ S Protein of unknown function (DUF2639)
COEIJKGJ_03743 6.4e-122 yflK S protein conserved in bacteria
COEIJKGJ_03744 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COEIJKGJ_03745 2.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
COEIJKGJ_03746 2.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
COEIJKGJ_03747 1.9e-226 citM C Citrate transporter
COEIJKGJ_03748 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
COEIJKGJ_03749 8.9e-119 citT T response regulator
COEIJKGJ_03750 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
COEIJKGJ_03751 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
COEIJKGJ_03752 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
COEIJKGJ_03753 7.6e-58 yflT S Heat induced stress protein YflT
COEIJKGJ_03754 2.9e-24 S Protein of unknown function (DUF3212)
COEIJKGJ_03755 2.7e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
COEIJKGJ_03756 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_03757 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
COEIJKGJ_03758 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
COEIJKGJ_03759 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
COEIJKGJ_03760 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
COEIJKGJ_03761 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
COEIJKGJ_03762 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
COEIJKGJ_03763 1.5e-209 yfmO EGP Major facilitator Superfamily
COEIJKGJ_03764 4e-69 yfmP K transcriptional
COEIJKGJ_03765 3.4e-74 yfmQ S Uncharacterised protein from bacillus cereus group
COEIJKGJ_03766 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
COEIJKGJ_03767 1.1e-113 yfmS NT chemotaxis protein
COEIJKGJ_03768 1.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
COEIJKGJ_03769 1.4e-240 yfnA E amino acid
COEIJKGJ_03770 3.9e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COEIJKGJ_03771 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
COEIJKGJ_03772 3.3e-188 yfnD M Nucleotide-diphospho-sugar transferase
COEIJKGJ_03773 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
COEIJKGJ_03774 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
COEIJKGJ_03775 1.9e-172 yfnG 4.2.1.45 M dehydratase
COEIJKGJ_03776 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
COEIJKGJ_03777 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
COEIJKGJ_03778 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
COEIJKGJ_03779 3.6e-199 yetN S Protein of unknown function (DUF3900)
COEIJKGJ_03780 8.3e-31 yetM CH FAD binding domain
COEIJKGJ_03781 2.6e-104 yetJ S Belongs to the BI1 family
COEIJKGJ_03782 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
COEIJKGJ_03783 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
COEIJKGJ_03784 2.2e-34
COEIJKGJ_03785 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COEIJKGJ_03786 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
COEIJKGJ_03787 4e-122 yetF S membrane
COEIJKGJ_03788 8.9e-256 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
COEIJKGJ_03789 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
COEIJKGJ_03790 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
COEIJKGJ_03791 1.5e-288 lplA G Bacterial extracellular solute-binding protein
COEIJKGJ_03792 0.0 yetA
COEIJKGJ_03793 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
COEIJKGJ_03794 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
COEIJKGJ_03795 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
COEIJKGJ_03796 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
COEIJKGJ_03797 2.2e-111 yesV S Protein of unknown function, DUF624
COEIJKGJ_03798 3e-127 yesU S Domain of unknown function (DUF1961)
COEIJKGJ_03799 5.1e-130 E GDSL-like Lipase/Acylhydrolase
COEIJKGJ_03800 0.0 yesS K Transcriptional regulator
COEIJKGJ_03801 3.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
COEIJKGJ_03802 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
COEIJKGJ_03803 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
COEIJKGJ_03804 1.6e-246 yesO G Bacterial extracellular solute-binding protein
COEIJKGJ_03805 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
COEIJKGJ_03806 0.0 yesM 2.7.13.3 T Histidine kinase
COEIJKGJ_03807 1.2e-101 yesL S Protein of unknown function, DUF624
COEIJKGJ_03808 1.3e-101 yesJ K Acetyltransferase (GNAT) family
COEIJKGJ_03809 5.2e-104 cotJC P Spore Coat
COEIJKGJ_03810 1.5e-45 cotJB S CotJB protein
COEIJKGJ_03811 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
COEIJKGJ_03812 5.5e-142 yesF GM NAD(P)H-binding
COEIJKGJ_03813 2.5e-77 yesE S SnoaL-like domain
COEIJKGJ_03814 8.5e-102 dhaR3 K Transcriptional regulator
COEIJKGJ_03816 2.7e-126 yeeN K transcriptional regulatory protein
COEIJKGJ_03818 1.6e-213 S Tetratricopeptide repeat
COEIJKGJ_03819 1e-39
COEIJKGJ_03820 4.1e-26 3.4.24.40 CO amine dehydrogenase activity
COEIJKGJ_03821 2e-125 3.4.24.40 CO amine dehydrogenase activity
COEIJKGJ_03822 8.7e-101 L endonuclease activity
COEIJKGJ_03824 0.0 L nucleic acid phosphodiester bond hydrolysis
COEIJKGJ_03825 4.2e-75 S Protein of unknown function, DUF600
COEIJKGJ_03826 2.7e-27
COEIJKGJ_03828 1.4e-100 S response regulator aspartate phosphatase
COEIJKGJ_03830 5.8e-43
COEIJKGJ_03832 0.0 L Type III restriction enzyme res subunit
COEIJKGJ_03833 1.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COEIJKGJ_03834 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
COEIJKGJ_03835 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
COEIJKGJ_03836 1.3e-148 yerO K Transcriptional regulator
COEIJKGJ_03837 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COEIJKGJ_03838 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COEIJKGJ_03839 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COEIJKGJ_03840 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COEIJKGJ_03841 6.1e-123 sapB S MgtC SapB transporter
COEIJKGJ_03842 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
COEIJKGJ_03843 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
COEIJKGJ_03844 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COEIJKGJ_03845 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COEIJKGJ_03846 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
COEIJKGJ_03847 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
COEIJKGJ_03848 4.8e-51 yerC S protein conserved in bacteria
COEIJKGJ_03849 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
COEIJKGJ_03850 0.0 yerA 3.5.4.2 F adenine deaminase
COEIJKGJ_03851 2.7e-27 S Protein of unknown function (DUF2892)
COEIJKGJ_03852 6.4e-227 yjeH E Amino acid permease
COEIJKGJ_03853 3.5e-73 K helix_turn_helix ASNC type
COEIJKGJ_03854 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
COEIJKGJ_03855 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COEIJKGJ_03856 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COEIJKGJ_03857 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COEIJKGJ_03858 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COEIJKGJ_03859 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEIJKGJ_03860 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEIJKGJ_03861 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COEIJKGJ_03862 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
COEIJKGJ_03863 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COEIJKGJ_03864 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COEIJKGJ_03865 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COEIJKGJ_03866 8e-28 yebG S NETI protein
COEIJKGJ_03867 8.9e-93 yebE S UPF0316 protein
COEIJKGJ_03869 8.3e-116 yebC M Membrane
COEIJKGJ_03870 7.8e-212 pbuG S permease
COEIJKGJ_03871 9.8e-256 S Domain of unknown function (DUF4179)
COEIJKGJ_03872 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
COEIJKGJ_03873 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COEIJKGJ_03874 0.0 yebA E COG1305 Transglutaminase-like enzymes
COEIJKGJ_03875 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
COEIJKGJ_03876 1.5e-175 yeaC S COG0714 MoxR-like ATPases
COEIJKGJ_03877 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COEIJKGJ_03878 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
COEIJKGJ_03879 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
COEIJKGJ_03880 3.3e-175 yeaA S Protein of unknown function (DUF4003)
COEIJKGJ_03881 8.4e-156 ydjP I Alpha/beta hydrolase family
COEIJKGJ_03882 1.4e-34 ydjO S Cold-inducible protein YdjO
COEIJKGJ_03884 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
COEIJKGJ_03885 4.5e-64 ydjM M Lytic transglycolase
COEIJKGJ_03886 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
COEIJKGJ_03887 2.7e-258 iolT EGP Major facilitator Superfamily
COEIJKGJ_03888 4.7e-196 S Ion transport 2 domain protein
COEIJKGJ_03889 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
COEIJKGJ_03890 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
COEIJKGJ_03891 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COEIJKGJ_03892 5.1e-114 pspA KT Phage shock protein A
COEIJKGJ_03893 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
COEIJKGJ_03894 7.1e-256 gutA G MFS/sugar transport protein
COEIJKGJ_03895 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
COEIJKGJ_03896 0.0 K NB-ARC domain
COEIJKGJ_03897 1.1e-08 ydjC S Abhydrolase domain containing 18
COEIJKGJ_03898 4.9e-257 J LlaJI restriction endonuclease
COEIJKGJ_03899 1.2e-199 V AAA domain (dynein-related subfamily)
COEIJKGJ_03901 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
COEIJKGJ_03902 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
COEIJKGJ_03903 6.4e-66 KL Phage plasmid primase P4 family
COEIJKGJ_03905 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COEIJKGJ_03906 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COEIJKGJ_03907 7.9e-129 ydiL S CAAX protease self-immunity
COEIJKGJ_03908 2.9e-27 ydiK S Domain of unknown function (DUF4305)
COEIJKGJ_03909 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
COEIJKGJ_03910 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
COEIJKGJ_03911 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COEIJKGJ_03912 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
COEIJKGJ_03913 0.0 ydiF S ABC transporter
COEIJKGJ_03914 2e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COEIJKGJ_03915 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
COEIJKGJ_03916 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
COEIJKGJ_03917 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
COEIJKGJ_03918 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
COEIJKGJ_03920 7.8e-08
COEIJKGJ_03921 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
COEIJKGJ_03922 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
COEIJKGJ_03923 1.2e-84 gerD
COEIJKGJ_03924 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
COEIJKGJ_03925 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
COEIJKGJ_03926 9.7e-66 ybaK S Protein of unknown function (DUF2521)
COEIJKGJ_03927 3.4e-143 ybaJ Q Methyltransferase domain
COEIJKGJ_03928 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
COEIJKGJ_03929 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COEIJKGJ_03930 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COEIJKGJ_03931 4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEIJKGJ_03932 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEIJKGJ_03933 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COEIJKGJ_03934 3.6e-58 rplQ J Ribosomal protein L17
COEIJKGJ_03935 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEIJKGJ_03936 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COEIJKGJ_03937 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COEIJKGJ_03938 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
COEIJKGJ_03939 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COEIJKGJ_03940 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
COEIJKGJ_03941 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COEIJKGJ_03942 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COEIJKGJ_03943 1.8e-72 rplO J binds to the 23S rRNA
COEIJKGJ_03944 1.9e-23 rpmD J Ribosomal protein L30
COEIJKGJ_03945 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COEIJKGJ_03946 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COEIJKGJ_03947 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COEIJKGJ_03948 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COEIJKGJ_03949 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COEIJKGJ_03950 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COEIJKGJ_03951 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COEIJKGJ_03952 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COEIJKGJ_03953 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COEIJKGJ_03954 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
COEIJKGJ_03955 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COEIJKGJ_03956 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COEIJKGJ_03957 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COEIJKGJ_03958 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COEIJKGJ_03959 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COEIJKGJ_03960 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COEIJKGJ_03961 3e-105 rplD J Forms part of the polypeptide exit tunnel
COEIJKGJ_03962 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COEIJKGJ_03963 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COEIJKGJ_03964 2.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
COEIJKGJ_03965 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COEIJKGJ_03966 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COEIJKGJ_03967 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COEIJKGJ_03968 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COEIJKGJ_03969 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
COEIJKGJ_03970 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEIJKGJ_03971 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COEIJKGJ_03972 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
COEIJKGJ_03973 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COEIJKGJ_03974 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COEIJKGJ_03975 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COEIJKGJ_03976 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COEIJKGJ_03977 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
COEIJKGJ_03978 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COEIJKGJ_03979 4.4e-115 sigH K Belongs to the sigma-70 factor family
COEIJKGJ_03980 1.2e-88 yacP S RNA-binding protein containing a PIN domain
COEIJKGJ_03981 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COEIJKGJ_03982 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COEIJKGJ_03983 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COEIJKGJ_03984 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
COEIJKGJ_03985 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COEIJKGJ_03986 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
COEIJKGJ_03987 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
COEIJKGJ_03988 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
COEIJKGJ_03989 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
COEIJKGJ_03990 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COEIJKGJ_03991 0.0 clpC O Belongs to the ClpA ClpB family
COEIJKGJ_03992 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
COEIJKGJ_03993 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
COEIJKGJ_03994 2.9e-76 ctsR K Belongs to the CtsR family
COEIJKGJ_03995 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COEIJKGJ_03996 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COEIJKGJ_03997 4.1e-30 yazB K transcriptional
COEIJKGJ_03998 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
COEIJKGJ_03999 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COEIJKGJ_04000 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
COEIJKGJ_04001 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
COEIJKGJ_04002 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
COEIJKGJ_04003 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
COEIJKGJ_04004 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COEIJKGJ_04005 4.4e-135 yacD 5.2.1.8 O peptidyl-prolyl isomerase
COEIJKGJ_04006 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COEIJKGJ_04007 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
COEIJKGJ_04008 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COEIJKGJ_04009 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COEIJKGJ_04010 4.2e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COEIJKGJ_04011 3.7e-185 KLT serine threonine protein kinase
COEIJKGJ_04012 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
COEIJKGJ_04013 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
COEIJKGJ_04016 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
COEIJKGJ_04017 1.1e-44 divIC D Septum formation initiator
COEIJKGJ_04018 2.5e-107 yabQ S spore cortex biosynthesis protein
COEIJKGJ_04019 1.5e-49 yabP S Sporulation protein YabP
COEIJKGJ_04020 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
COEIJKGJ_04021 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
COEIJKGJ_04022 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
COEIJKGJ_04023 1.5e-92 spoVT K stage V sporulation protein
COEIJKGJ_04024 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COEIJKGJ_04025 2.4e-39 yabK S Peptide ABC transporter permease
COEIJKGJ_04026 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COEIJKGJ_04027 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
COEIJKGJ_04028 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COEIJKGJ_04029 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COEIJKGJ_04030 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
COEIJKGJ_04031 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
COEIJKGJ_04032 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
COEIJKGJ_04033 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COEIJKGJ_04034 8.3e-27 sspF S DNA topological change
COEIJKGJ_04035 7.8e-39 veg S protein conserved in bacteria
COEIJKGJ_04036 1.6e-136 yabG S peptidase
COEIJKGJ_04037 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COEIJKGJ_04038 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COEIJKGJ_04039 2e-167 rpfB GH23 T protein conserved in bacteria
COEIJKGJ_04040 1.2e-143 tatD L hydrolase, TatD
COEIJKGJ_04041 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COEIJKGJ_04042 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
COEIJKGJ_04043 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COEIJKGJ_04044 2.8e-48 yazA L endonuclease containing a URI domain
COEIJKGJ_04045 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
COEIJKGJ_04046 4.8e-31 yabA L Involved in initiation control of chromosome replication
COEIJKGJ_04047 6.1e-146 yaaT S stage 0 sporulation protein
COEIJKGJ_04048 1.1e-181 holB 2.7.7.7 L DNA polymerase III
COEIJKGJ_04049 1.5e-71 yaaR S protein conserved in bacteria
COEIJKGJ_04050 2.2e-54 yaaQ S protein conserved in bacteria
COEIJKGJ_04051 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COEIJKGJ_04052 2.7e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
COEIJKGJ_04053 1.4e-201 yaaN P Belongs to the TelA family
COEIJKGJ_04054 2.4e-102 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
COEIJKGJ_04055 1.7e-30 csfB S Inhibitor of sigma-G Gin
COEIJKGJ_04056 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
COEIJKGJ_04057 7.9e-32 yaaL S Protein of unknown function (DUF2508)
COEIJKGJ_04058 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COEIJKGJ_04059 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COEIJKGJ_04060 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COEIJKGJ_04061 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COEIJKGJ_04062 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
COEIJKGJ_04063 5.6e-215 yaaH M Glycoside Hydrolase Family
COEIJKGJ_04064 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
COEIJKGJ_04065 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
COEIJKGJ_04066 1.3e-09
COEIJKGJ_04067 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COEIJKGJ_04068 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
COEIJKGJ_04069 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
COEIJKGJ_04070 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COEIJKGJ_04071 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
COEIJKGJ_04072 1e-181 yaaC S YaaC-like Protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)