ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDLNJKFM_00001 5.6e-114 fruR K transcriptional
HDLNJKFM_00002 5.5e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDLNJKFM_00003 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
HDLNJKFM_00004 5.9e-50 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
HDLNJKFM_00005 4.9e-208 fruA 2.7.1.202 G phosphotransferase system
HDLNJKFM_00006 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HDLNJKFM_00007 8.1e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDLNJKFM_00009 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
HDLNJKFM_00010 3.8e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDLNJKFM_00011 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HDLNJKFM_00012 2.1e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HDLNJKFM_00013 6.4e-29 2.3.1.128 K acetyltransferase
HDLNJKFM_00014 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDLNJKFM_00015 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDLNJKFM_00016 3e-127 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDLNJKFM_00017 2.6e-64 WQ51_03320 S cog cog4835
HDLNJKFM_00018 6.4e-61 XK27_08360 S EDD domain protein, DegV family
HDLNJKFM_00019 3.6e-74 XK27_08360 S EDD domain protein, DegV family
HDLNJKFM_00020 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDLNJKFM_00021 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDLNJKFM_00022 0.0 yfmR S abc transporter atp-binding protein
HDLNJKFM_00023 8.9e-23 U response to pH
HDLNJKFM_00024 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
HDLNJKFM_00025 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
HDLNJKFM_00026 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDLNJKFM_00027 3.3e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDLNJKFM_00028 1.9e-77 K DNA-binding transcription factor activity
HDLNJKFM_00029 0.0 lmrA1 V abc transporter atp-binding protein
HDLNJKFM_00030 0.0 lmrA2 V abc transporter atp-binding protein
HDLNJKFM_00031 1.6e-44 K Acetyltransferase (GNAT) family
HDLNJKFM_00032 3e-117 sptS 2.7.13.3 T Histidine kinase
HDLNJKFM_00033 3.2e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDLNJKFM_00034 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDLNJKFM_00035 1.7e-159 cvfB S Protein conserved in bacteria
HDLNJKFM_00036 7.4e-35 yozE S Belongs to the UPF0346 family
HDLNJKFM_00037 3.3e-117 sip M LysM domain protein
HDLNJKFM_00038 8e-191 phoH T phosphate starvation-inducible protein PhoH
HDLNJKFM_00042 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDLNJKFM_00043 1.2e-166 K transcriptional regulator (lysR family)
HDLNJKFM_00044 1.4e-186 coiA 3.6.4.12 S Competence protein
HDLNJKFM_00045 0.0 pepF E oligoendopeptidase F
HDLNJKFM_00046 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
HDLNJKFM_00047 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
HDLNJKFM_00048 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDLNJKFM_00049 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HDLNJKFM_00050 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HDLNJKFM_00051 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
HDLNJKFM_00052 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HDLNJKFM_00053 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
HDLNJKFM_00054 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDLNJKFM_00055 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDLNJKFM_00056 5.1e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HDLNJKFM_00057 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HDLNJKFM_00058 5.9e-131 yxkH G deacetylase
HDLNJKFM_00059 5.2e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HDLNJKFM_00060 1.7e-151 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDLNJKFM_00061 1e-151 rarD S Transporter
HDLNJKFM_00062 4.4e-16 T peptidase
HDLNJKFM_00063 8.9e-14 coiA 3.6.4.12 S Competence protein
HDLNJKFM_00064 5.7e-106 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HDLNJKFM_00065 5.3e-74 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDLNJKFM_00066 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDLNJKFM_00067 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDLNJKFM_00068 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
HDLNJKFM_00069 2.3e-76 atpF C ATP synthase F(0) sector subunit b
HDLNJKFM_00070 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDLNJKFM_00071 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDLNJKFM_00072 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDLNJKFM_00073 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDLNJKFM_00074 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDLNJKFM_00075 1.4e-229 ftsW D Belongs to the SEDS family
HDLNJKFM_00076 3.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDLNJKFM_00077 3.4e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDLNJKFM_00078 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDLNJKFM_00079 6.4e-162 holB 2.7.7.7 L dna polymerase iii
HDLNJKFM_00080 3e-124 yaaT S stage 0 sporulation protein
HDLNJKFM_00081 9.5e-55 yabA L Involved in initiation control of chromosome replication
HDLNJKFM_00082 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDLNJKFM_00083 4.9e-232 amt P Ammonium Transporter
HDLNJKFM_00084 1.1e-53 glnB K Belongs to the P(II) protein family
HDLNJKFM_00085 4.9e-106 mur1 NU mannosyl-glycoprotein
HDLNJKFM_00086 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
HDLNJKFM_00087 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
HDLNJKFM_00088 3.6e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDLNJKFM_00089 1.8e-53
HDLNJKFM_00090 7.5e-26
HDLNJKFM_00091 3.9e-60
HDLNJKFM_00092 6.1e-63 S membrane
HDLNJKFM_00093 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDLNJKFM_00094 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDLNJKFM_00095 4.5e-39 ynzC S UPF0291 protein
HDLNJKFM_00096 1.8e-254 cycA E permease
HDLNJKFM_00097 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
HDLNJKFM_00098 9.1e-23 pts33BCA G pts system
HDLNJKFM_00099 3.3e-37 pts33BCA G pts system
HDLNJKFM_00100 9e-96 pts33BCA G pts system
HDLNJKFM_00101 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
HDLNJKFM_00102 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDLNJKFM_00107 1.4e-167 fhuR K transcriptional regulator (lysR family)
HDLNJKFM_00108 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDLNJKFM_00109 1.9e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDLNJKFM_00110 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDLNJKFM_00111 4.9e-227 pyrP F uracil Permease
HDLNJKFM_00112 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HDLNJKFM_00113 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
HDLNJKFM_00114 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
HDLNJKFM_00115 7.1e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
HDLNJKFM_00116 4.4e-30 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HDLNJKFM_00117 1.2e-46 V efflux transmembrane transporter activity
HDLNJKFM_00118 3.1e-31 V efflux transmembrane transporter activity
HDLNJKFM_00119 8.2e-28 ytrF V efflux transmembrane transporter activity
HDLNJKFM_00120 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDLNJKFM_00121 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDLNJKFM_00122 2.1e-185 L Transposase
HDLNJKFM_00123 1.6e-18 L Integrase core domain
HDLNJKFM_00124 6e-109 devA 3.6.3.25 V abc transporter atp-binding protein
HDLNJKFM_00125 2.8e-164 hrtB V MacB-like periplasmic core domain
HDLNJKFM_00128 3e-92 S MucBP domain
HDLNJKFM_00129 5.9e-51 M YSIRK type signal peptide
HDLNJKFM_00130 3.4e-288 M the current gene model (or a revised gene model) may contain a
HDLNJKFM_00132 0.0 mdlB V abc transporter atp-binding protein
HDLNJKFM_00133 0.0 lmrA V abc transporter atp-binding protein
HDLNJKFM_00134 2.8e-196 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDLNJKFM_00135 3.7e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDLNJKFM_00136 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
HDLNJKFM_00137 2.5e-132 rr02 KT response regulator
HDLNJKFM_00138 1.3e-218 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HDLNJKFM_00139 2.8e-168 V ABC transporter
HDLNJKFM_00140 5.4e-122 sagI S ABC-2 type transporter
HDLNJKFM_00141 1.5e-196 yceA S Belongs to the UPF0176 family
HDLNJKFM_00142 2.3e-27 XK27_00085 K Transcriptional
HDLNJKFM_00143 7.3e-22
HDLNJKFM_00144 1.4e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
HDLNJKFM_00145 2.5e-113 S VIT family
HDLNJKFM_00146 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDLNJKFM_00147 2.6e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HDLNJKFM_00148 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
HDLNJKFM_00149 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HDLNJKFM_00150 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HDLNJKFM_00151 4.6e-105 GBS0088 J protein conserved in bacteria
HDLNJKFM_00152 7.4e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HDLNJKFM_00153 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HDLNJKFM_00154 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
HDLNJKFM_00155 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDLNJKFM_00156 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDLNJKFM_00157 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
HDLNJKFM_00158 2.1e-07
HDLNJKFM_00159 4.5e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDLNJKFM_00161 3.5e-07 U protein secretion
HDLNJKFM_00162 2.1e-50 U protein secretion
HDLNJKFM_00164 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
HDLNJKFM_00165 4.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HDLNJKFM_00166 2.7e-49 XK27_13030
HDLNJKFM_00167 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDLNJKFM_00168 7.1e-48 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDLNJKFM_00169 1.4e-69 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HDLNJKFM_00170 4e-164 S Protein of unknown function (DUF3114)
HDLNJKFM_00171 3.6e-22 S Protein of unknown function (DUF3114)
HDLNJKFM_00172 1.5e-118 yqfA K protein, Hemolysin III
HDLNJKFM_00173 1e-25 K hmm pf08876
HDLNJKFM_00174 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HDLNJKFM_00175 1.7e-218 mvaS 2.3.3.10 I synthase
HDLNJKFM_00176 6.5e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDLNJKFM_00177 2.2e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDLNJKFM_00178 9.7e-22
HDLNJKFM_00179 2.2e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDLNJKFM_00180 1.5e-109 engB D Necessary for normal cell division and for the maintenance of normal septation
HDLNJKFM_00181 9.2e-248 mmuP E amino acid
HDLNJKFM_00182 1.4e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
HDLNJKFM_00183 1.4e-29 S Domain of unknown function (DUF1912)
HDLNJKFM_00184 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
HDLNJKFM_00185 2.3e-100 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDLNJKFM_00186 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDLNJKFM_00187 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDLNJKFM_00188 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
HDLNJKFM_00189 4.8e-16 S Protein of unknown function (DUF2969)
HDLNJKFM_00192 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
HDLNJKFM_00195 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
HDLNJKFM_00196 1e-69 M Pfam SNARE associated Golgi protein
HDLNJKFM_00197 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
HDLNJKFM_00198 1.6e-08 S oxidoreductase
HDLNJKFM_00199 9.3e-59 S oxidoreductase
HDLNJKFM_00200 9.7e-66 S oxidoreductase
HDLNJKFM_00201 2.4e-47 XK27_09445 S Domain of unknown function (DUF1827)
HDLNJKFM_00202 5.7e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HDLNJKFM_00203 0.0 clpE O Belongs to the ClpA ClpB family
HDLNJKFM_00204 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDLNJKFM_00205 1.3e-34 ykuJ S protein conserved in bacteria
HDLNJKFM_00206 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
HDLNJKFM_00207 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLNJKFM_00208 1.1e-78 feoA P FeoA domain protein
HDLNJKFM_00209 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HDLNJKFM_00210 1.5e-07
HDLNJKFM_00211 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HDLNJKFM_00212 2.2e-45 K sequence-specific DNA binding
HDLNJKFM_00213 2.5e-33 yugF I carboxylic ester hydrolase activity
HDLNJKFM_00214 7.5e-23 I Alpha/beta hydrolase family
HDLNJKFM_00215 3.7e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDLNJKFM_00216 5.4e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDLNJKFM_00217 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
HDLNJKFM_00218 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDLNJKFM_00219 5.4e-43 licT K transcriptional antiterminator
HDLNJKFM_00220 6.8e-53 licT K transcriptional antiterminator
HDLNJKFM_00221 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDLNJKFM_00222 8.3e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HDLNJKFM_00223 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDLNJKFM_00224 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDLNJKFM_00225 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDLNJKFM_00226 4e-128 mdtG EGP Major facilitator Superfamily
HDLNJKFM_00227 9.5e-74 mdtG EGP Major facilitator Superfamily
HDLNJKFM_00228 2e-33 secG U Preprotein translocase subunit SecG
HDLNJKFM_00229 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDLNJKFM_00230 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDLNJKFM_00231 5.3e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDLNJKFM_00232 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
HDLNJKFM_00233 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
HDLNJKFM_00234 4.4e-183 ccpA K Catabolite control protein A
HDLNJKFM_00235 2.8e-28 yyaQ S YjbR
HDLNJKFM_00236 6.6e-101 yyaQ V Protein conserved in bacteria
HDLNJKFM_00237 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDLNJKFM_00238 7.4e-77 yueI S Protein of unknown function (DUF1694)
HDLNJKFM_00239 1.3e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDLNJKFM_00241 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HDLNJKFM_00242 2e-219 ywbD 2.1.1.191 J Methyltransferase
HDLNJKFM_00243 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDLNJKFM_00244 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDLNJKFM_00245 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDLNJKFM_00246 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDLNJKFM_00247 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HDLNJKFM_00248 3.2e-53 yheA S Belongs to the UPF0342 family
HDLNJKFM_00249 3.9e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HDLNJKFM_00250 4.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDLNJKFM_00251 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDLNJKFM_00252 5.1e-153 pheA 4.2.1.51 E Prephenate dehydratase
HDLNJKFM_00253 1.1e-251 msrR K Transcriptional regulator
HDLNJKFM_00254 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
HDLNJKFM_00255 4.1e-203 I acyl-CoA dehydrogenase
HDLNJKFM_00256 4.5e-97 mip S hydroperoxide reductase activity
HDLNJKFM_00257 6.5e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDLNJKFM_00258 1.2e-19
HDLNJKFM_00259 3.2e-46
HDLNJKFM_00260 1e-31 K Cro/C1-type HTH DNA-binding domain
HDLNJKFM_00261 3e-49 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HDLNJKFM_00262 6.3e-33 estA E GDSL-like Lipase/Acylhydrolase
HDLNJKFM_00263 1.1e-94
HDLNJKFM_00264 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDLNJKFM_00265 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLNJKFM_00266 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLNJKFM_00267 4.2e-192 S CRISPR-associated protein Csn2 subfamily St
HDLNJKFM_00268 1.3e-148 ycgQ S TIGR03943 family
HDLNJKFM_00269 3.5e-155 XK27_03015 S permease
HDLNJKFM_00271 0.0 yhgF K Transcriptional accessory protein
HDLNJKFM_00272 9.9e-42 pspC KT PspC domain
HDLNJKFM_00273 5.8e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDLNJKFM_00274 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDLNJKFM_00276 5.5e-69 ytxH S General stress protein
HDLNJKFM_00278 2e-177 yegQ O Peptidase U32
HDLNJKFM_00279 3.4e-252 yegQ O Peptidase U32
HDLNJKFM_00280 3.5e-86 bioY S biotin synthase
HDLNJKFM_00282 1.1e-33 XK27_12190 S protein conserved in bacteria
HDLNJKFM_00283 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
HDLNJKFM_00284 3.3e-12
HDLNJKFM_00285 3.1e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
HDLNJKFM_00286 6.2e-99 L helicase
HDLNJKFM_00287 2.1e-39
HDLNJKFM_00288 6.3e-38
HDLNJKFM_00292 7.8e-19 pvuIIC K Helix-turn-helix domain
HDLNJKFM_00293 6.2e-64
HDLNJKFM_00294 3.7e-161 haeIIIM 2.1.1.37 L C-5 cytosine-specific DNA methylase
HDLNJKFM_00295 4.4e-24 S Protein of unknown function (DUF1643)
HDLNJKFM_00296 7.5e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDLNJKFM_00297 1.9e-15 M LysM domain
HDLNJKFM_00298 3.7e-52 M LysM domain
HDLNJKFM_00299 1.6e-62 M LysM domain
HDLNJKFM_00300 3.4e-16
HDLNJKFM_00301 2.3e-175 S hydrolase
HDLNJKFM_00302 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
HDLNJKFM_00303 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDLNJKFM_00304 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
HDLNJKFM_00305 2.7e-27 P Hemerythrin HHE cation binding domain protein
HDLNJKFM_00306 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HDLNJKFM_00307 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
HDLNJKFM_00308 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
HDLNJKFM_00309 2.4e-40 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLNJKFM_00310 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
HDLNJKFM_00311 6.2e-288 hsdM 2.1.1.72 V N-6 DNA Methylase
HDLNJKFM_00312 1.2e-139 3.1.21.3 V type I restriction modification DNA specificity domain
HDLNJKFM_00314 9.2e-173 spd F DNA RNA non-specific endonuclease
HDLNJKFM_00315 6.5e-91 lemA S LemA family
HDLNJKFM_00316 1.2e-131 htpX O Belongs to the peptidase M48B family
HDLNJKFM_00317 2.1e-74 S Psort location CytoplasmicMembrane, score
HDLNJKFM_00318 5.3e-55 S Domain of unknown function (DUF4430)
HDLNJKFM_00319 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HDLNJKFM_00320 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HDLNJKFM_00321 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
HDLNJKFM_00322 1.3e-185 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
HDLNJKFM_00323 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HDLNJKFM_00324 3.2e-92 dps P Belongs to the Dps family
HDLNJKFM_00325 8.9e-80 perR P Belongs to the Fur family
HDLNJKFM_00326 1.9e-27 yqgQ S protein conserved in bacteria
HDLNJKFM_00327 3e-176 glk 2.7.1.2 G Glucokinase
HDLNJKFM_00328 0.0 typA T GTP-binding protein TypA
HDLNJKFM_00330 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDLNJKFM_00331 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDLNJKFM_00332 5.7e-171 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDLNJKFM_00333 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDLNJKFM_00334 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDLNJKFM_00335 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HDLNJKFM_00336 6.8e-96 sepF D cell septum assembly
HDLNJKFM_00337 4.4e-34 yggT D integral membrane protein
HDLNJKFM_00338 1.6e-143 ylmH T S4 RNA-binding domain
HDLNJKFM_00339 1.8e-135 divIVA D Cell division protein DivIVA
HDLNJKFM_00340 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDLNJKFM_00341 7.9e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
HDLNJKFM_00342 2e-45 rpmE2 J 50S ribosomal protein L31
HDLNJKFM_00343 1.2e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDLNJKFM_00344 7.6e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
HDLNJKFM_00345 2.6e-154 gst O Glutathione S-transferase
HDLNJKFM_00346 6.7e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HDLNJKFM_00347 3.5e-111 tdk 2.7.1.21 F thymidine kinase
HDLNJKFM_00348 2.6e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDLNJKFM_00349 1e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDLNJKFM_00350 2.8e-108 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDLNJKFM_00351 4e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDLNJKFM_00352 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
HDLNJKFM_00353 1.6e-106 pvaA M lytic transglycosylase activity
HDLNJKFM_00356 7.3e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDLNJKFM_00357 8.1e-91 K transcriptional regulator
HDLNJKFM_00358 7.6e-36 yneF S UPF0154 protein
HDLNJKFM_00359 3.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDLNJKFM_00360 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDLNJKFM_00361 3.5e-99 XK27_09740 S Phosphoesterase
HDLNJKFM_00362 5.4e-86 ykuL S CBS domain
HDLNJKFM_00363 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
HDLNJKFM_00364 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDLNJKFM_00365 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDLNJKFM_00366 4.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDLNJKFM_00367 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HDLNJKFM_00368 1.2e-258 trkH P Cation transport protein
HDLNJKFM_00369 1.5e-247 trkA P Potassium transporter peripheral membrane component
HDLNJKFM_00370 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDLNJKFM_00371 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDLNJKFM_00372 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
HDLNJKFM_00373 2.5e-161 K sequence-specific DNA binding
HDLNJKFM_00374 1.9e-33 V protein secretion by the type I secretion system
HDLNJKFM_00375 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLNJKFM_00376 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLNJKFM_00377 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLNJKFM_00378 3.7e-51 yhaI L Membrane
HDLNJKFM_00379 6.7e-36 S Domain of unknown function (DUF4173)
HDLNJKFM_00380 9.2e-132 S Domain of unknown function (DUF4173)
HDLNJKFM_00381 6.8e-95 ureI S AmiS/UreI family transporter
HDLNJKFM_00382 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HDLNJKFM_00383 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HDLNJKFM_00384 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HDLNJKFM_00385 6.6e-78 ureE O enzyme active site formation
HDLNJKFM_00386 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HDLNJKFM_00387 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HDLNJKFM_00388 3.7e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HDLNJKFM_00389 2.7e-177 cbiM P PDGLE domain
HDLNJKFM_00390 1.1e-136 P cobalt transport protein
HDLNJKFM_00391 1.6e-131 cbiO P ABC transporter
HDLNJKFM_00392 7.1e-150 ET amino acid transport
HDLNJKFM_00393 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
HDLNJKFM_00394 1.2e-82 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
HDLNJKFM_00395 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HDLNJKFM_00396 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
HDLNJKFM_00397 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDLNJKFM_00398 8.8e-98 metI P ABC transporter (Permease
HDLNJKFM_00399 6.7e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HDLNJKFM_00400 3.2e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
HDLNJKFM_00401 9.4e-95 S UPF0397 protein
HDLNJKFM_00402 0.0 ykoD P abc transporter atp-binding protein
HDLNJKFM_00403 2e-149 cbiQ P cobalt transport
HDLNJKFM_00404 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDLNJKFM_00405 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
HDLNJKFM_00406 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HDLNJKFM_00407 9.8e-242 P COG0168 Trk-type K transport systems, membrane components
HDLNJKFM_00408 9e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
HDLNJKFM_00409 8.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
HDLNJKFM_00410 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLNJKFM_00411 8e-277 T PhoQ Sensor
HDLNJKFM_00412 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDLNJKFM_00413 1.4e-217 dnaB L Replication initiation and membrane attachment
HDLNJKFM_00414 4e-167 dnaI L Primosomal protein DnaI
HDLNJKFM_00415 5.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDLNJKFM_00417 1.2e-34
HDLNJKFM_00418 3e-27 L Integrase core domain protein
HDLNJKFM_00419 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HDLNJKFM_00420 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDLNJKFM_00421 8.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDLNJKFM_00422 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDLNJKFM_00423 2.7e-48 S glycolate biosynthetic process
HDLNJKFM_00424 3.4e-64 S phosphatase activity
HDLNJKFM_00425 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
HDLNJKFM_00428 7.8e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDLNJKFM_00429 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDLNJKFM_00430 6.4e-37 yeeD O sulfur carrier activity
HDLNJKFM_00431 3.6e-188 yeeE S Sulphur transport
HDLNJKFM_00432 1.8e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDLNJKFM_00433 2.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDLNJKFM_00434 5.4e-09 S Domain of unknown function (DUF4651)
HDLNJKFM_00435 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HDLNJKFM_00436 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDLNJKFM_00437 3.9e-111 S CAAX amino terminal protease family protein
HDLNJKFM_00439 5e-67 V CAAX protease self-immunity
HDLNJKFM_00440 2.6e-26 lanR K sequence-specific DNA binding
HDLNJKFM_00441 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDLNJKFM_00442 5.9e-177 ytxK 2.1.1.72 L DNA methylase
HDLNJKFM_00443 6.8e-13 comGF U Putative Competence protein ComGF
HDLNJKFM_00444 9.9e-71 comGF U Competence protein ComGF
HDLNJKFM_00445 1.4e-15 NU Type II secretory pathway pseudopilin
HDLNJKFM_00446 1.8e-57 cglD NU Competence protein
HDLNJKFM_00447 9.4e-42 comGC U Required for transformation and DNA binding
HDLNJKFM_00448 1.1e-156 cglB U protein transport across the cell outer membrane
HDLNJKFM_00449 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HDLNJKFM_00450 2.9e-68 S cog cog4699
HDLNJKFM_00451 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLNJKFM_00452 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLNJKFM_00453 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDLNJKFM_00454 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDLNJKFM_00455 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HDLNJKFM_00456 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
HDLNJKFM_00457 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
HDLNJKFM_00458 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HDLNJKFM_00459 3.5e-302 yloV S kinase related to dihydroxyacetone kinase
HDLNJKFM_00460 4e-57 asp S cog cog1302
HDLNJKFM_00461 1.1e-223 norN V Mate efflux family protein
HDLNJKFM_00462 2.4e-278 thrC 4.2.3.1 E Threonine synthase
HDLNJKFM_00463 8.8e-63 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDLNJKFM_00464 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
HDLNJKFM_00465 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDLNJKFM_00466 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDLNJKFM_00467 5.3e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
HDLNJKFM_00468 0.0 pepO 3.4.24.71 O Peptidase family M13
HDLNJKFM_00469 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HDLNJKFM_00470 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HDLNJKFM_00471 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HDLNJKFM_00472 1.9e-54 treB 2.7.1.201 G PTS System
HDLNJKFM_00473 5.8e-21 treR K DNA-binding transcription factor activity
HDLNJKFM_00474 8.6e-87 treR K trehalose operon
HDLNJKFM_00475 7.4e-95 ywlG S Belongs to the UPF0340 family
HDLNJKFM_00477 6.9e-262 yfiB1 V abc transporter atp-binding protein
HDLNJKFM_00478 0.0 XK27_10035 V abc transporter atp-binding protein
HDLNJKFM_00479 1.5e-09 S D-Ala-teichoic acid biosynthesis protein
HDLNJKFM_00480 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLNJKFM_00481 3.9e-237 dltB M Membrane protein involved in D-alanine export
HDLNJKFM_00482 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDLNJKFM_00483 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDLNJKFM_00484 7e-33 L Integrase core domain protein
HDLNJKFM_00485 9.6e-32 L transposition
HDLNJKFM_00486 4.2e-10 L transposase activity
HDLNJKFM_00487 3.6e-39 L Transposase
HDLNJKFM_00488 0.0 3.6.3.8 P cation transport ATPase
HDLNJKFM_00489 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
HDLNJKFM_00491 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDLNJKFM_00492 1.1e-164 metF 1.5.1.20 C reductase
HDLNJKFM_00493 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HDLNJKFM_00494 1.1e-93 panT S ECF transporter, substrate-specific component
HDLNJKFM_00495 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDLNJKFM_00496 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
HDLNJKFM_00497 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HDLNJKFM_00498 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLNJKFM_00499 1.4e-39 T PhoQ Sensor
HDLNJKFM_00500 7.2e-42 T PhoQ Sensor
HDLNJKFM_00501 4.3e-124 T PhoQ Sensor
HDLNJKFM_00502 2.1e-30 rpsT J rRNA binding
HDLNJKFM_00503 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
HDLNJKFM_00504 2.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
HDLNJKFM_00505 2.3e-26 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HDLNJKFM_00506 5.1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
HDLNJKFM_00507 1.2e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
HDLNJKFM_00508 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDLNJKFM_00509 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HDLNJKFM_00510 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HDLNJKFM_00511 2.6e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HDLNJKFM_00512 3.5e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HDLNJKFM_00513 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
HDLNJKFM_00514 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
HDLNJKFM_00515 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HDLNJKFM_00516 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDLNJKFM_00517 3.1e-81 ypmB S Protein conserved in bacteria
HDLNJKFM_00518 6.1e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HDLNJKFM_00519 1.2e-260 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HDLNJKFM_00520 2.5e-15
HDLNJKFM_00521 2e-53 L Transposase
HDLNJKFM_00522 5.4e-22
HDLNJKFM_00523 1.5e-12
HDLNJKFM_00524 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
HDLNJKFM_00525 1.3e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HDLNJKFM_00526 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HDLNJKFM_00527 6.7e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HDLNJKFM_00528 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
HDLNJKFM_00529 4.9e-168 XK27_01785 S cog cog1284
HDLNJKFM_00530 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDLNJKFM_00532 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDLNJKFM_00533 5.7e-52 metE 2.1.1.14 E Methionine synthase
HDLNJKFM_00534 7.6e-64 metE 2.1.1.14 E Methionine synthase
HDLNJKFM_00535 9.2e-36 metE 2.1.1.14 E Methionine synthase
HDLNJKFM_00536 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HDLNJKFM_00537 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDLNJKFM_00539 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
HDLNJKFM_00540 2.7e-95 S Hydrophobic domain protein
HDLNJKFM_00542 3.7e-27 S Membrane
HDLNJKFM_00543 3.1e-101
HDLNJKFM_00544 1.8e-23 S Small integral membrane protein
HDLNJKFM_00545 1.1e-71 M Protein conserved in bacteria
HDLNJKFM_00546 4.9e-12 K CsbD-like
HDLNJKFM_00547 1.7e-96 nudL L hydrolase
HDLNJKFM_00548 3.4e-13 nudL L hydrolase
HDLNJKFM_00549 8e-49 K transcriptional regulator, PadR family
HDLNJKFM_00551 1.1e-105 S Putative adhesin
HDLNJKFM_00552 3.6e-159 XK27_06930 V domain protein
HDLNJKFM_00553 3.5e-94 XK27_06935 K transcriptional regulator
HDLNJKFM_00554 9.1e-54 ypaA S membrane
HDLNJKFM_00555 1.8e-08
HDLNJKFM_00556 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDLNJKFM_00557 8.2e-48 veg S Biofilm formation stimulator VEG
HDLNJKFM_00558 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDLNJKFM_00559 2e-69 rplI J binds to the 23S rRNA
HDLNJKFM_00560 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDLNJKFM_00561 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDLNJKFM_00562 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDLNJKFM_00563 0.0 S Bacterial membrane protein, YfhO
HDLNJKFM_00564 1.3e-87 isaA GH23 M Immunodominant staphylococcal antigen A
HDLNJKFM_00565 1.7e-91 lytE M LysM domain protein
HDLNJKFM_00566 3.8e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLNJKFM_00567 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLNJKFM_00568 7.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDLNJKFM_00569 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDLNJKFM_00570 3.7e-138 ymfM S sequence-specific DNA binding
HDLNJKFM_00571 1.4e-242 ymfH S Peptidase M16
HDLNJKFM_00572 5.1e-156 ymfF S Peptidase M16
HDLNJKFM_00573 1.7e-66 ymfF S Peptidase M16
HDLNJKFM_00574 1.6e-45 yaaA S S4 domain protein YaaA
HDLNJKFM_00575 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDLNJKFM_00576 3.8e-31 hmpT S membrane
HDLNJKFM_00577 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
HDLNJKFM_00578 8.5e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDLNJKFM_00579 1.1e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDLNJKFM_00580 9.8e-298 dnaK O Heat shock 70 kDa protein
HDLNJKFM_00581 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDLNJKFM_00582 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDLNJKFM_00583 1.3e-102 acmA 3.2.1.17 NU amidase activity
HDLNJKFM_00584 1.2e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HDLNJKFM_00585 1.5e-129 ais G Phosphoglycerate mutase
HDLNJKFM_00586 1.9e-242 XK27_08635 S UPF0210 protein
HDLNJKFM_00587 3.6e-39 gcvR T UPF0237 protein
HDLNJKFM_00588 9.1e-223 capA M Bacterial capsule synthesis protein
HDLNJKFM_00589 1.5e-121 tnp L Transposase IS66 family
HDLNJKFM_00590 6.8e-76 isp2 S pathogenesis
HDLNJKFM_00592 3.7e-118
HDLNJKFM_00594 8.7e-41 S Helix-turn-helix domain
HDLNJKFM_00595 4.5e-83 int L Belongs to the 'phage' integrase family
HDLNJKFM_00596 8.5e-112 int L Belongs to the 'phage' integrase family
HDLNJKFM_00597 1.8e-70 2.7.7.49 L DNA polymerase
HDLNJKFM_00600 2.8e-09 S Sigma-70, region 4
HDLNJKFM_00601 7.4e-44
HDLNJKFM_00602 4.6e-194 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HDLNJKFM_00603 4.8e-55
HDLNJKFM_00604 5.2e-91 S Plasmid replication protein
HDLNJKFM_00605 8.3e-24
HDLNJKFM_00606 4.8e-188 L Phage integrase family
HDLNJKFM_00607 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HDLNJKFM_00608 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDLNJKFM_00609 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDLNJKFM_00610 4.7e-32 K helix-turn-helix
HDLNJKFM_00611 1.7e-154 degV S DegV family
HDLNJKFM_00612 3.5e-91 yacP S RNA-binding protein containing a PIN domain
HDLNJKFM_00613 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDLNJKFM_00616 5.5e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDLNJKFM_00617 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDLNJKFM_00618 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
HDLNJKFM_00619 6.9e-144 S SseB protein N-terminal domain
HDLNJKFM_00620 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HDLNJKFM_00621 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDLNJKFM_00622 7.8e-28 L transposase activity
HDLNJKFM_00623 2.1e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDLNJKFM_00624 4.2e-62 manO S protein conserved in bacteria
HDLNJKFM_00625 9.6e-169 manN G PTS system mannose fructose sorbose family IID component
HDLNJKFM_00626 3.9e-116 manM G pts system
HDLNJKFM_00627 1.1e-181 manL 2.7.1.191 G pts system
HDLNJKFM_00628 7.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
HDLNJKFM_00629 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HDLNJKFM_00630 8.3e-244 pbuO S permease
HDLNJKFM_00631 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
HDLNJKFM_00632 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
HDLNJKFM_00633 3.4e-217 brpA K Transcriptional
HDLNJKFM_00634 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
HDLNJKFM_00635 3.1e-212 nusA K Participates in both transcription termination and antitermination
HDLNJKFM_00636 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
HDLNJKFM_00637 1.4e-41 ylxQ J ribosomal protein
HDLNJKFM_00638 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDLNJKFM_00639 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDLNJKFM_00640 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
HDLNJKFM_00641 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
HDLNJKFM_00642 4.5e-233 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
HDLNJKFM_00643 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDLNJKFM_00644 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
HDLNJKFM_00645 8.1e-83 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
HDLNJKFM_00646 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
HDLNJKFM_00647 1.1e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HDLNJKFM_00649 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
HDLNJKFM_00650 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDLNJKFM_00651 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDLNJKFM_00652 3.4e-74 ylbF S Belongs to the UPF0342 family
HDLNJKFM_00653 7.1e-46 ylbG S UPF0298 protein
HDLNJKFM_00654 1.2e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
HDLNJKFM_00655 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
HDLNJKFM_00656 2.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
HDLNJKFM_00657 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
HDLNJKFM_00658 1.4e-122 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HDLNJKFM_00659 2.8e-70 acuB S IMP dehydrogenase activity
HDLNJKFM_00660 4.7e-42 acuB S IMP dehydrogenase activity
HDLNJKFM_00661 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDLNJKFM_00662 6.3e-111 yvyE 3.4.13.9 S YigZ family
HDLNJKFM_00663 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HDLNJKFM_00664 7.6e-123 comFC S Competence protein
HDLNJKFM_00665 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDLNJKFM_00666 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
HDLNJKFM_00667 2e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
HDLNJKFM_00668 4.4e-75 XK27_10720 D peptidase activity
HDLNJKFM_00669 3.6e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
HDLNJKFM_00670 1.7e-08
HDLNJKFM_00671 1.5e-24 L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
HDLNJKFM_00672 4.2e-49 L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
HDLNJKFM_00673 9.4e-60
HDLNJKFM_00674 1.1e-250 L Transposase
HDLNJKFM_00675 1e-171 yeiH S Membrane
HDLNJKFM_00676 1.6e-118 mur1 NU muramidase
HDLNJKFM_00677 4.2e-20 L transposase activity
HDLNJKFM_00678 4.5e-166 cpsY K Transcriptional regulator
HDLNJKFM_00679 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDLNJKFM_00680 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
HDLNJKFM_00681 4e-105 artQ P ABC transporter (Permease
HDLNJKFM_00682 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLNJKFM_00683 1.2e-157 aatB ET ABC transporter substrate-binding protein
HDLNJKFM_00684 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLNJKFM_00685 2.1e-07
HDLNJKFM_00686 8.1e-60 adhP 1.1.1.1 C alcohol dehydrogenase
HDLNJKFM_00687 1.6e-21 adhP 1.1.1.1 C alcohol dehydrogenase
HDLNJKFM_00688 5.3e-58 adhP 1.1.1.1 C alcohol dehydrogenase
HDLNJKFM_00689 0.0 res_1 3.1.21.5 S Type III restriction
HDLNJKFM_00690 1.2e-158 sthIM 2.1.1.72 L DNA methylase
HDLNJKFM_00691 8.5e-88 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
HDLNJKFM_00692 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDLNJKFM_00693 2e-126 gntR1 K transcriptional
HDLNJKFM_00694 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDLNJKFM_00695 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDLNJKFM_00696 9.1e-87 niaX
HDLNJKFM_00697 6e-91 niaR S small molecule binding protein (contains 3H domain)
HDLNJKFM_00698 8.1e-128 K DNA-binding helix-turn-helix protein
HDLNJKFM_00699 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDLNJKFM_00700 2.6e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDLNJKFM_00701 4.1e-167 GK ROK family
HDLNJKFM_00702 3.6e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDLNJKFM_00703 3.4e-62 yqhY S protein conserved in bacteria
HDLNJKFM_00704 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDLNJKFM_00705 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
HDLNJKFM_00706 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
HDLNJKFM_00708 8e-44 V 'abc transporter, ATP-binding protein
HDLNJKFM_00709 1e-58 V 'abc transporter, ATP-binding protein
HDLNJKFM_00712 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HDLNJKFM_00713 5e-168 corA P COG0598 Mg2 and Co2 transporters
HDLNJKFM_00714 3.1e-124 XK27_01040 S Pfam PF06570
HDLNJKFM_00716 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDLNJKFM_00717 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDLNJKFM_00718 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
HDLNJKFM_00719 2.8e-41 XK27_05745
HDLNJKFM_00720 2.5e-230 mutY L A G-specific adenine glycosylase
HDLNJKFM_00725 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDLNJKFM_00726 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDLNJKFM_00727 6.7e-93 cvpA S toxin biosynthetic process
HDLNJKFM_00728 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDLNJKFM_00729 1e-159 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDLNJKFM_00730 1.3e-111 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDLNJKFM_00731 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDLNJKFM_00732 8.8e-48 azlD E branched-chain amino acid
HDLNJKFM_00733 8.5e-117 azlC E AzlC protein
HDLNJKFM_00734 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDLNJKFM_00735 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDLNJKFM_00736 1.4e-119 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
HDLNJKFM_00737 2.5e-33 ykzG S Belongs to the UPF0356 family
HDLNJKFM_00738 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDLNJKFM_00739 5.8e-69 nodC 2.4.1.212 GT2 M Glycosyl transferase family 21
HDLNJKFM_00740 2.7e-121 nodC 2.4.1.212 GT2 M Chitin synthase
HDLNJKFM_00741 2.6e-214 ugd 1.1.1.22 M UDP binding domain
HDLNJKFM_00742 1.2e-09 L Transposase
HDLNJKFM_00743 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
HDLNJKFM_00744 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDLNJKFM_00745 2e-140 1.1.1.169 H Ketopantoate reductase
HDLNJKFM_00746 1.6e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDLNJKFM_00747 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDLNJKFM_00748 6.5e-240 purD 6.3.4.13 F Belongs to the GARS family
HDLNJKFM_00749 6.4e-159 S CHAP domain
HDLNJKFM_00750 1.4e-33 L Integrase core domain protein
HDLNJKFM_00751 1.4e-48 L transposition
HDLNJKFM_00752 3.1e-75 L transposase activity
HDLNJKFM_00753 8.1e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HDLNJKFM_00754 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDLNJKFM_00755 1.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HDLNJKFM_00756 8.6e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDLNJKFM_00757 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDLNJKFM_00758 1.2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HDLNJKFM_00759 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDLNJKFM_00760 2.5e-43 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDLNJKFM_00761 8.8e-131 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDLNJKFM_00762 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
HDLNJKFM_00763 5.9e-219 araT 2.6.1.1 E Aminotransferase
HDLNJKFM_00764 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDLNJKFM_00765 5.1e-94 usp 3.5.1.28 CBM50 S CHAP domain
HDLNJKFM_00766 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HDLNJKFM_00767 8e-138 mreC M Involved in formation and maintenance of cell shape
HDLNJKFM_00769 4e-50 L Transposase
HDLNJKFM_00770 8.7e-84 L Transposase
HDLNJKFM_00771 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDLNJKFM_00772 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDLNJKFM_00773 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDLNJKFM_00774 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
HDLNJKFM_00776 2.7e-61 divIC D Septum formation initiator
HDLNJKFM_00777 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HDLNJKFM_00778 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDLNJKFM_00779 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDLNJKFM_00780 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDLNJKFM_00781 1.1e-29 yyzM S Protein conserved in bacteria
HDLNJKFM_00782 8.2e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDLNJKFM_00783 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDLNJKFM_00784 8.5e-134 parB K Belongs to the ParB family
HDLNJKFM_00785 8.7e-197 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
HDLNJKFM_00786 6.2e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDLNJKFM_00787 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
HDLNJKFM_00791 0.0 XK27_10405 S Bacterial membrane protein YfhO
HDLNJKFM_00792 5.7e-305 ybiT S abc transporter atp-binding protein
HDLNJKFM_00793 5.4e-153 yvjA S membrane
HDLNJKFM_00794 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HDLNJKFM_00795 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HDLNJKFM_00796 1.2e-299 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDLNJKFM_00797 4.6e-112 ywaF S Integral membrane protein (intg_mem_TP0381)
HDLNJKFM_00798 8.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDLNJKFM_00801 1.1e-155 cjaA ET ABC transporter substrate-binding protein
HDLNJKFM_00802 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLNJKFM_00803 1.3e-114 P ABC transporter (Permease
HDLNJKFM_00804 1e-114 papP P ABC transporter (Permease
HDLNJKFM_00805 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDLNJKFM_00806 1.8e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
HDLNJKFM_00807 0.0 copA 3.6.3.54 P P-type ATPase
HDLNJKFM_00808 8e-73 copY K Copper transport repressor, CopY TcrY family
HDLNJKFM_00809 2.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDLNJKFM_00810 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDLNJKFM_00811 1.8e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
HDLNJKFM_00812 5.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HDLNJKFM_00813 2.3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDLNJKFM_00814 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
HDLNJKFM_00815 1.4e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HDLNJKFM_00816 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
HDLNJKFM_00817 3.2e-56
HDLNJKFM_00818 0.0 ctpE P E1-E2 ATPase
HDLNJKFM_00819 6.1e-27
HDLNJKFM_00821 1.1e-128 S Protein conserved in bacteria
HDLNJKFM_00822 4.2e-110
HDLNJKFM_00823 3.6e-44
HDLNJKFM_00824 1.8e-17
HDLNJKFM_00826 4.4e-176 dcm_2 2.1.1.37 L C-5 cytosine-specific DNA methylase
HDLNJKFM_00827 1.1e-159 dcm 2.1.1.37 H PFAM C-5 cytosine-specific DNA methylase
HDLNJKFM_00828 1.2e-133 L NgoFVII restriction endonuclease
HDLNJKFM_00829 1.3e-10 L NgoFVII restriction endonuclease
HDLNJKFM_00830 9.2e-24 isp2 S pathogenesis
HDLNJKFM_00831 7.4e-14 isp2 S pathogenesis
HDLNJKFM_00832 9.5e-18 isp2 S pathogenesis
HDLNJKFM_00833 4.8e-14 S Domain of unknown function (DUF3173)
HDLNJKFM_00834 1.1e-81 L Belongs to the 'phage' integrase family
HDLNJKFM_00835 3.8e-86 L Belongs to the 'phage' integrase family
HDLNJKFM_00836 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDLNJKFM_00837 2.1e-28 L transposase activity
HDLNJKFM_00838 3.5e-121 K transcriptional regulator, MerR family
HDLNJKFM_00839 5e-102 dnaQ 2.7.7.7 L DNA polymerase III
HDLNJKFM_00840 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
HDLNJKFM_00841 1.6e-63 XK27_02560 S cog cog2151
HDLNJKFM_00842 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HDLNJKFM_00843 2.2e-226 ytfP S Flavoprotein
HDLNJKFM_00845 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDLNJKFM_00846 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
HDLNJKFM_00847 5.1e-182 ecsB U ABC transporter
HDLNJKFM_00848 2.3e-133 ecsA V abc transporter atp-binding protein
HDLNJKFM_00849 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HDLNJKFM_00850 2.3e-10
HDLNJKFM_00851 1.3e-56 S CD20-like family
HDLNJKFM_00852 3.2e-110
HDLNJKFM_00853 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
HDLNJKFM_00854 1.9e-200 ylbM S Belongs to the UPF0348 family
HDLNJKFM_00855 2e-140 yqeM Q Methyltransferase domain protein
HDLNJKFM_00856 1.3e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDLNJKFM_00857 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HDLNJKFM_00858 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDLNJKFM_00859 3.5e-49 yhbY J RNA-binding protein
HDLNJKFM_00860 4.9e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HDLNJKFM_00861 1.8e-98 yqeG S hydrolase of the HAD superfamily
HDLNJKFM_00862 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDLNJKFM_00863 1.2e-58
HDLNJKFM_00864 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDLNJKFM_00865 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDLNJKFM_00866 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDLNJKFM_00867 2.4e-30 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HDLNJKFM_00868 1e-234 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDLNJKFM_00869 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLNJKFM_00870 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
HDLNJKFM_00871 6.8e-101 pncA Q isochorismatase
HDLNJKFM_00872 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HDLNJKFM_00873 1.1e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
HDLNJKFM_00874 6.9e-75 XK27_03180 T universal stress protein
HDLNJKFM_00876 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDLNJKFM_00877 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
HDLNJKFM_00878 2.6e-08 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HDLNJKFM_00879 3.5e-117 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
HDLNJKFM_00880 0.0 yjcE P NhaP-type Na H and K H antiporters
HDLNJKFM_00882 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
HDLNJKFM_00883 8.4e-184 yhcC S radical SAM protein
HDLNJKFM_00884 8.4e-196 ylbL T Belongs to the peptidase S16 family
HDLNJKFM_00885 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDLNJKFM_00886 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
HDLNJKFM_00887 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDLNJKFM_00888 3.2e-09 S Protein of unknown function (DUF4059)
HDLNJKFM_00889 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
HDLNJKFM_00890 4.7e-163 yxeN P ABC transporter (Permease
HDLNJKFM_00891 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HDLNJKFM_00893 2.3e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLNJKFM_00894 0.0 pflB 2.3.1.54 C formate acetyltransferase'
HDLNJKFM_00895 7.5e-62 cah 4.2.1.1 P carbonic anhydrase
HDLNJKFM_00896 2e-45 cah 4.2.1.1 P carbonic anhydrase
HDLNJKFM_00897 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDLNJKFM_00898 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
HDLNJKFM_00899 2.9e-87 D nuclear chromosome segregation
HDLNJKFM_00900 2.7e-32 L DNA integration
HDLNJKFM_00901 9.3e-124 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
HDLNJKFM_00902 1.5e-127 ybbM S transport system, permease component
HDLNJKFM_00903 1.2e-117 ybbL S abc transporter atp-binding protein
HDLNJKFM_00904 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
HDLNJKFM_00905 4.6e-140 cppA E CppA N-terminal
HDLNJKFM_00906 5e-44 V CAAX protease self-immunity
HDLNJKFM_00907 2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HDLNJKFM_00908 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDLNJKFM_00911 3e-47 spiA K sequence-specific DNA binding
HDLNJKFM_00912 9.5e-140 blpT
HDLNJKFM_00918 8.9e-133 agrA KT phosphorelay signal transduction system
HDLNJKFM_00919 1.3e-238 blpH 2.7.13.3 T protein histidine kinase activity
HDLNJKFM_00921 6.2e-236 mesE M Transport protein ComB
HDLNJKFM_00922 1.3e-279 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLNJKFM_00923 2.8e-108 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDLNJKFM_00924 0.0 mdlB V abc transporter atp-binding protein
HDLNJKFM_00925 0.0 mdlA V abc transporter atp-binding protein
HDLNJKFM_00927 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
HDLNJKFM_00928 5.6e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HDLNJKFM_00929 3.6e-70 yutD J protein conserved in bacteria
HDLNJKFM_00930 5.1e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDLNJKFM_00932 4.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDLNJKFM_00933 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDLNJKFM_00934 0.0 ftsI 3.4.16.4 M penicillin-binding protein
HDLNJKFM_00935 1.2e-46 ftsL D cell division protein FtsL
HDLNJKFM_00936 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDLNJKFM_00937 8.5e-111
HDLNJKFM_00938 8.7e-33 yhaI J Protein of unknown function (DUF805)
HDLNJKFM_00939 1.3e-08 D nuclear chromosome segregation
HDLNJKFM_00940 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDLNJKFM_00941 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDLNJKFM_00942 6.2e-288 XK27_00765
HDLNJKFM_00943 1.4e-133 ecsA_2 V abc transporter atp-binding protein
HDLNJKFM_00944 2.5e-47 S Protein of unknown function (DUF554)
HDLNJKFM_00945 8.5e-32 S Protein of unknown function (DUF554)
HDLNJKFM_00946 1.6e-11 S Protein of unknown function (DUF554)
HDLNJKFM_00947 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDLNJKFM_00948 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
HDLNJKFM_00949 2.4e-55 liaI S membrane
HDLNJKFM_00950 7e-10 XK27_02470 K LytTr DNA-binding domain protein
HDLNJKFM_00951 1.2e-30 KT response to antibiotic
HDLNJKFM_00952 9.3e-31 KT response to antibiotic
HDLNJKFM_00953 9.1e-18 KT response to antibiotic
HDLNJKFM_00954 8.3e-79 yebC M Membrane
HDLNJKFM_00955 1.1e-16 yebC M Membrane
HDLNJKFM_00956 1.6e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
HDLNJKFM_00957 9.4e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HDLNJKFM_00959 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDLNJKFM_00960 6.4e-183 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDLNJKFM_00961 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDLNJKFM_00962 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HDLNJKFM_00963 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HDLNJKFM_00964 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDLNJKFM_00966 3.7e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDLNJKFM_00967 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
HDLNJKFM_00968 0.0 scrA 2.7.1.211 G pts system
HDLNJKFM_00969 6e-290 scrB 3.2.1.26 GH32 G invertase
HDLNJKFM_00970 3.7e-179 scrR K Transcriptional
HDLNJKFM_00973 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
HDLNJKFM_00974 6.4e-108 S Domain of unknown function (DUF1803)
HDLNJKFM_00975 1.3e-101 ygaC J Belongs to the UPF0374 family
HDLNJKFM_00976 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
HDLNJKFM_00977 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDLNJKFM_00978 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
HDLNJKFM_00979 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
HDLNJKFM_00980 1.9e-115 S Haloacid dehalogenase-like hydrolase
HDLNJKFM_00981 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
HDLNJKFM_00982 1.5e-71 marR K Transcriptional regulator, MarR family
HDLNJKFM_00983 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDLNJKFM_00984 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDLNJKFM_00985 2.6e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
HDLNJKFM_00986 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HDLNJKFM_00987 1.6e-126 IQ reductase
HDLNJKFM_00988 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDLNJKFM_00989 2e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDLNJKFM_00990 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDLNJKFM_00991 2.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HDLNJKFM_00992 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDLNJKFM_00993 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HDLNJKFM_00994 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDLNJKFM_00995 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
HDLNJKFM_00996 5.2e-84 L Transposase
HDLNJKFM_00997 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDLNJKFM_00998 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDLNJKFM_00999 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
HDLNJKFM_01000 6.4e-54 fnt P Formate nitrite transporter
HDLNJKFM_01001 1.9e-07 fnt P Formate nitrite transporter
HDLNJKFM_01002 2.3e-141 XK27_09615 C reductase
HDLNJKFM_01003 9e-62 XK27_09615 C reductase
HDLNJKFM_01004 4.3e-77 XK27_09620 S reductase
HDLNJKFM_01005 1.4e-19 XK27_09620 S FMN reductase (NADPH) activity
HDLNJKFM_01006 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HDLNJKFM_01007 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDLNJKFM_01008 8.1e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
HDLNJKFM_01009 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
HDLNJKFM_01010 1.1e-25 WQ51_05710 S Mitochondrial biogenesis AIM24
HDLNJKFM_01011 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HDLNJKFM_01012 9.2e-51 S Protein of unknown function (DUF3397)
HDLNJKFM_01013 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDLNJKFM_01014 2.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDLNJKFM_01015 4.2e-74 amiA E transmembrane transport
HDLNJKFM_01016 6.6e-63 amiA E transmembrane transport
HDLNJKFM_01017 2e-20 amiA E ABC transporter, substrate-binding protein, family 5
HDLNJKFM_01018 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDLNJKFM_01019 1.3e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDLNJKFM_01020 5.4e-264 argH 4.3.2.1 E Argininosuccinate lyase
HDLNJKFM_01021 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDLNJKFM_01022 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDLNJKFM_01023 2e-186 jag S RNA-binding protein
HDLNJKFM_01024 1e-13 rpmH J Ribosomal protein L34
HDLNJKFM_01025 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HDLNJKFM_01026 3.5e-35 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDLNJKFM_01027 2.4e-275 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDLNJKFM_01028 6.6e-61 EGP Major facilitator Superfamily
HDLNJKFM_01029 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
HDLNJKFM_01030 1.3e-212 pqqE C radical SAM domain protein
HDLNJKFM_01033 5.2e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HDLNJKFM_01034 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDLNJKFM_01035 1.9e-100 IQ Acetoin reductase
HDLNJKFM_01036 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDLNJKFM_01037 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HDLNJKFM_01038 3.8e-153 XK27_05470 E Methionine synthase
HDLNJKFM_01039 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDLNJKFM_01040 9e-251 T PhoQ Sensor
HDLNJKFM_01041 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLNJKFM_01042 3.6e-154 S TraX protein
HDLNJKFM_01043 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDLNJKFM_01044 9e-29 dprA LU DNA protecting protein DprA
HDLNJKFM_01045 1.5e-97 ybhL S Belongs to the BI1 family
HDLNJKFM_01046 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
HDLNJKFM_01047 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDLNJKFM_01048 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDLNJKFM_01049 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDLNJKFM_01050 2.5e-83 L Integrase core domain protein
HDLNJKFM_01051 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDLNJKFM_01052 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDLNJKFM_01053 3.5e-82 XK27_09675 K -acetyltransferase
HDLNJKFM_01054 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDLNJKFM_01055 2.5e-23
HDLNJKFM_01056 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
HDLNJKFM_01057 7.2e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
HDLNJKFM_01058 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDLNJKFM_01059 4.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDLNJKFM_01060 4.9e-93 ypsA S Belongs to the UPF0398 family
HDLNJKFM_01061 2.4e-107 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDLNJKFM_01062 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDLNJKFM_01063 3.3e-62 rplQ J ribosomal protein l17
HDLNJKFM_01064 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDLNJKFM_01065 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDLNJKFM_01066 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDLNJKFM_01067 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HDLNJKFM_01068 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDLNJKFM_01069 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDLNJKFM_01070 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDLNJKFM_01071 4.4e-58 rplO J binds to the 23S rRNA
HDLNJKFM_01072 2.5e-23 rpmD J ribosomal protein l30
HDLNJKFM_01073 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDLNJKFM_01074 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDLNJKFM_01075 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDLNJKFM_01076 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDLNJKFM_01077 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDLNJKFM_01078 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDLNJKFM_01079 5.3e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDLNJKFM_01080 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDLNJKFM_01081 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDLNJKFM_01082 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
HDLNJKFM_01083 1e-69 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDLNJKFM_01084 9.8e-115 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDLNJKFM_01085 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDLNJKFM_01086 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDLNJKFM_01087 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDLNJKFM_01088 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDLNJKFM_01089 7.4e-104 rplD J Forms part of the polypeptide exit tunnel
HDLNJKFM_01090 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDLNJKFM_01091 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HDLNJKFM_01092 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDLNJKFM_01093 0.0 XK27_09800 I Acyltransferase
HDLNJKFM_01094 1.7e-35 XK27_09805 S MORN repeat protein
HDLNJKFM_01095 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDLNJKFM_01096 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDLNJKFM_01097 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDLNJKFM_01098 0.0 clpC O Belongs to the ClpA ClpB family
HDLNJKFM_01099 6.2e-76 ctsR K Belongs to the CtsR family
HDLNJKFM_01100 1.1e-83 S Putative small multi-drug export protein
HDLNJKFM_01101 5.1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDLNJKFM_01102 1.2e-135 rpsB J Belongs to the universal ribosomal protein uS2 family
HDLNJKFM_01104 5.4e-09 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HDLNJKFM_01105 1.8e-150 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HDLNJKFM_01107 1.3e-42 L transposition
HDLNJKFM_01108 2e-88 L Integrase core domain protein
HDLNJKFM_01109 1.6e-94 S reductase
HDLNJKFM_01110 2e-42 badR K DNA-binding transcription factor activity
HDLNJKFM_01111 5.5e-36 XK27_02060 S Transglycosylase associated protein
HDLNJKFM_01112 2.8e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HDLNJKFM_01113 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDLNJKFM_01118 1.9e-07
HDLNJKFM_01121 4e-42
HDLNJKFM_01122 7.6e-55 S TM2 domain
HDLNJKFM_01123 4e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDLNJKFM_01124 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDLNJKFM_01125 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
HDLNJKFM_01126 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
HDLNJKFM_01127 3.7e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
HDLNJKFM_01128 1.3e-45 cof Q phosphatase activity
HDLNJKFM_01129 1.9e-31 cof Q phosphatase activity
HDLNJKFM_01130 4.4e-77 glcR K transcriptional regulator (DeoR family)
HDLNJKFM_01131 3.9e-21 glcR K transcriptional regulator (DeoR family)
HDLNJKFM_01132 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDLNJKFM_01133 7.6e-41 K transcriptional
HDLNJKFM_01134 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
HDLNJKFM_01135 6.2e-137 S COG1073 Hydrolases of the alpha beta superfamily
HDLNJKFM_01136 2.4e-278 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDLNJKFM_01137 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDLNJKFM_01138 1.9e-77 yhaI L Membrane
HDLNJKFM_01139 5.1e-259 pepC 3.4.22.40 E aminopeptidase
HDLNJKFM_01140 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
HDLNJKFM_01141 2e-09 L thioesterase
HDLNJKFM_01142 2.5e-141 S Macro domain protein
HDLNJKFM_01143 4.8e-51 trxA O Belongs to the thioredoxin family
HDLNJKFM_01144 1.5e-74 yccU S CoA-binding protein
HDLNJKFM_01145 1.6e-143 tatD L Hydrolase, tatd
HDLNJKFM_01146 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDLNJKFM_01147 5.2e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDLNJKFM_01149 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDLNJKFM_01150 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDLNJKFM_01151 9.2e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDLNJKFM_01152 6.9e-173 rmuC S RmuC domain protein
HDLNJKFM_01153 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
HDLNJKFM_01154 2.4e-142 purR 2.4.2.7 F operon repressor
HDLNJKFM_01155 5.1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDLNJKFM_01156 4.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDLNJKFM_01157 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDLNJKFM_01158 4.3e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDLNJKFM_01159 1.1e-86 L Integrase core domain protein
HDLNJKFM_01160 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
HDLNJKFM_01161 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDLNJKFM_01162 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
HDLNJKFM_01163 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
HDLNJKFM_01164 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDLNJKFM_01166 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDLNJKFM_01168 2.1e-68 K LytTr DNA-binding domain
HDLNJKFM_01169 1.5e-77 S Protein of unknown function (DUF3021)
HDLNJKFM_01170 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDLNJKFM_01171 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HDLNJKFM_01172 8.2e-70 argR K Regulates arginine biosynthesis genes
HDLNJKFM_01174 3.8e-57 T Toxic component of a toxin-antitoxin (TA) module
HDLNJKFM_01177 3.5e-28 3.4.13.21 I Protein conserved in bacteria
HDLNJKFM_01178 9e-89 FNV0100 F Belongs to the Nudix hydrolase family
HDLNJKFM_01179 3.8e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HDLNJKFM_01180 9.7e-30 S Domain of unknown function (DUF4649)
HDLNJKFM_01182 1.1e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
HDLNJKFM_01183 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDLNJKFM_01184 2.8e-44 yrzL S Belongs to the UPF0297 family
HDLNJKFM_01185 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDLNJKFM_01186 4.2e-44 yrzB S Belongs to the UPF0473 family
HDLNJKFM_01187 2.1e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
HDLNJKFM_01188 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HDLNJKFM_01189 7.5e-14
HDLNJKFM_01190 2.6e-91 XK27_10930 K acetyltransferase
HDLNJKFM_01191 1.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDLNJKFM_01192 2.4e-92 pat 2.3.1.183 M acetyltransferase
HDLNJKFM_01193 8.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDLNJKFM_01194 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDLNJKFM_01195 7.1e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDLNJKFM_01196 0.0 smc D Required for chromosome condensation and partitioning
HDLNJKFM_01197 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDLNJKFM_01198 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDLNJKFM_01199 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDLNJKFM_01202 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
HDLNJKFM_01203 1.4e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HDLNJKFM_01205 2e-86 S ECF-type riboflavin transporter, S component
HDLNJKFM_01206 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HDLNJKFM_01207 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
HDLNJKFM_01208 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
HDLNJKFM_01209 9.5e-294 yfmM S abc transporter atp-binding protein
HDLNJKFM_01210 4.4e-258 noxE P NADH oxidase
HDLNJKFM_01211 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDLNJKFM_01212 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDLNJKFM_01213 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
HDLNJKFM_01214 3.9e-53 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
HDLNJKFM_01215 1.8e-165 ypuA S secreted protein
HDLNJKFM_01216 3.3e-26 L Transposase (IS116 IS110 IS902 family)
HDLNJKFM_01217 4.2e-71 L Transposase (IS116 IS110 IS902 family)
HDLNJKFM_01219 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLNJKFM_01220 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDLNJKFM_01221 8.5e-34 nrdH O Glutaredoxin
HDLNJKFM_01222 4.5e-85 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HDLNJKFM_01223 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HDLNJKFM_01224 9.6e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
HDLNJKFM_01225 1.1e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
HDLNJKFM_01226 7.9e-39 ptsH G phosphocarrier protein Hpr
HDLNJKFM_01227 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDLNJKFM_01228 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
HDLNJKFM_01229 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDLNJKFM_01230 8.7e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
HDLNJKFM_01231 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HDLNJKFM_01232 0.0 uup S abc transporter atp-binding protein
HDLNJKFM_01233 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
HDLNJKFM_01234 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDLNJKFM_01235 8.7e-150 cobQ S glutamine amidotransferase
HDLNJKFM_01236 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
HDLNJKFM_01237 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDLNJKFM_01238 6e-169 ybbR S Protein conserved in bacteria
HDLNJKFM_01239 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDLNJKFM_01240 1.7e-70 gtrA S GtrA-like protein
HDLNJKFM_01241 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDLNJKFM_01242 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDLNJKFM_01243 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
HDLNJKFM_01244 6.3e-207 yurR 1.4.5.1 E oxidoreductase
HDLNJKFM_01245 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HDLNJKFM_01246 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HDLNJKFM_01247 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDLNJKFM_01251 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HDLNJKFM_01252 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
HDLNJKFM_01253 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDLNJKFM_01254 1.1e-121 ylfI S tigr01906
HDLNJKFM_01255 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
HDLNJKFM_01256 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HDLNJKFM_01257 1.4e-87 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
HDLNJKFM_01258 2.2e-33 XK27_08085
HDLNJKFM_01259 5.2e-36 L transposase activity
HDLNJKFM_01260 8.2e-22 L Transposase
HDLNJKFM_01261 1.9e-48 L transposition
HDLNJKFM_01262 3.1e-27 L Integrase core domain protein
HDLNJKFM_01263 1.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDLNJKFM_01264 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HDLNJKFM_01265 5.2e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDLNJKFM_01266 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDLNJKFM_01267 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HDLNJKFM_01268 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDLNJKFM_01269 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDLNJKFM_01270 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDLNJKFM_01271 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HDLNJKFM_01272 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
HDLNJKFM_01273 5.6e-240 rodA D Belongs to the SEDS family
HDLNJKFM_01274 5.4e-197 L transposase, IS4 family
HDLNJKFM_01275 5.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDLNJKFM_01276 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HDLNJKFM_01277 1e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDLNJKFM_01278 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLNJKFM_01279 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
HDLNJKFM_01280 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDLNJKFM_01281 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HDLNJKFM_01282 2.9e-125 dnaD
HDLNJKFM_01283 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDLNJKFM_01286 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDLNJKFM_01287 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
HDLNJKFM_01288 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDLNJKFM_01289 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HDLNJKFM_01290 3.7e-73 argR K Regulates arginine biosynthesis genes
HDLNJKFM_01291 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
HDLNJKFM_01292 1e-148 DegV S DegV family
HDLNJKFM_01293 6e-144 ypmR E lipolytic protein G-D-S-L family
HDLNJKFM_01294 2.1e-84 ypmS S Protein conserved in bacteria
HDLNJKFM_01295 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDLNJKFM_01297 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
HDLNJKFM_01298 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDLNJKFM_01299 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HDLNJKFM_01300 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HDLNJKFM_01301 1.3e-42 ysdA L Membrane
HDLNJKFM_01302 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDLNJKFM_01303 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HDLNJKFM_01304 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
HDLNJKFM_01305 0.0 dnaE 2.7.7.7 L DNA polymerase
HDLNJKFM_01306 2.1e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDLNJKFM_01307 6.7e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDLNJKFM_01308 2.9e-94 V VanZ like family
HDLNJKFM_01309 1.1e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HDLNJKFM_01310 3.7e-60 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
HDLNJKFM_01311 3.9e-102 G Belongs to the phosphoglycerate mutase family
HDLNJKFM_01312 1e-196 S hmm pf01594
HDLNJKFM_01313 8.4e-27 bglH 3.2.1.86 GT1 G beta-glucosidase activity
HDLNJKFM_01314 7.7e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDLNJKFM_01315 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
HDLNJKFM_01316 7.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDLNJKFM_01317 4.9e-39 S granule-associated protein
HDLNJKFM_01318 1.2e-291 S unusual protein kinase
HDLNJKFM_01319 3.4e-29 estA E Lysophospholipase L1 and related esterases
HDLNJKFM_01320 5.3e-69 estA E GDSL-like protein
HDLNJKFM_01321 6.7e-156 rssA S Phospholipase, patatin family
HDLNJKFM_01322 4.7e-71
HDLNJKFM_01323 2e-113 3.1.21.3 V type I restriction modification DNA specificity domain protein
HDLNJKFM_01324 9.5e-297 hsdM 2.1.1.72 V HsdM N-terminal domain
HDLNJKFM_01325 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HDLNJKFM_01326 2.4e-26
HDLNJKFM_01327 4.2e-18 D nuclear chromosome segregation
HDLNJKFM_01328 7e-136 yejC S cyclic nucleotide-binding protein
HDLNJKFM_01329 1.2e-163 rapZ S Displays ATPase and GTPase activities
HDLNJKFM_01330 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDLNJKFM_01331 8.7e-162 whiA K May be required for sporulation
HDLNJKFM_01332 6.8e-81 pepD E Dipeptidase
HDLNJKFM_01333 2.6e-44 pepD E Dipeptidase
HDLNJKFM_01334 1.5e-75 tspO T TspO/MBR family
HDLNJKFM_01335 1.9e-59 S Uncharacterised lipoprotein family
HDLNJKFM_01336 6.9e-08 IQ PFAM AMP-dependent synthetase and ligase
HDLNJKFM_01337 5.8e-109 MA20_06410 E LysE type translocator
HDLNJKFM_01338 5.6e-08
HDLNJKFM_01339 2.7e-09
HDLNJKFM_01340 0.0 M family 8
HDLNJKFM_01341 7.2e-86 L transposition
HDLNJKFM_01343 1.5e-39 L Integrase core domain
HDLNJKFM_01344 1.5e-46 waaB GT4 M Glycosyl transferases group 1
HDLNJKFM_01345 1.5e-07 cps2J S Polysaccharide biosynthesis protein
HDLNJKFM_01346 5e-148 L DDE domain
HDLNJKFM_01347 2.1e-42 L Transposase
HDLNJKFM_01348 1.4e-11 L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. orf1 of IS981
HDLNJKFM_01349 5.5e-29 capM K Cell envelope-related transcriptional attenuator domain
HDLNJKFM_01350 2.5e-98 capM K Cell envelope-related transcriptional attenuator domain
HDLNJKFM_01351 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
HDLNJKFM_01352 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
HDLNJKFM_01353 1.1e-109 6.3.2.2 H ergothioneine biosynthetic process
HDLNJKFM_01355 4.8e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
HDLNJKFM_01356 3.6e-132 L DNA integration
HDLNJKFM_01357 1.3e-87 S Fusaric acid resistance protein-like
HDLNJKFM_01358 8.5e-63 glnR K Transcriptional regulator
HDLNJKFM_01359 9.9e-263 glnA 6.3.1.2 E glutamine synthetase
HDLNJKFM_01360 1.1e-41 pscB M CHAP domain protein
HDLNJKFM_01361 8.9e-09 2.4.1.166 GT2 M Glycosyltransferase like family 2
HDLNJKFM_01362 2.3e-15
HDLNJKFM_01363 5.9e-73 M Glycosyltransferase sugar-binding region containing DXD motif
HDLNJKFM_01364 4.3e-41 pssE S Glycosyltransferase family 28 C-terminal domain
HDLNJKFM_01365 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDLNJKFM_01366 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDLNJKFM_01367 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDLNJKFM_01368 0.0 S the current gene model (or a revised gene model) may contain a frame shift
HDLNJKFM_01369 1e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HDLNJKFM_01370 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HDLNJKFM_01371 1.3e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDLNJKFM_01372 0.0 lpdA 1.8.1.4 C Dehydrogenase
HDLNJKFM_01373 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HDLNJKFM_01374 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
HDLNJKFM_01375 3.2e-265 3.5.1.28 NU amidase activity
HDLNJKFM_01376 1.9e-37 3.5.1.28 NU amidase activity
HDLNJKFM_01377 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLNJKFM_01378 1.2e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLNJKFM_01379 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLNJKFM_01380 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLNJKFM_01381 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HDLNJKFM_01382 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
HDLNJKFM_01383 1.5e-233 ycdB P peroxidase
HDLNJKFM_01384 2.6e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
HDLNJKFM_01385 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HDLNJKFM_01386 4.6e-25 tatA U protein secretion
HDLNJKFM_01387 2.3e-23 L Transposase
HDLNJKFM_01388 9.9e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
HDLNJKFM_01389 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDLNJKFM_01390 3.7e-09
HDLNJKFM_01393 3.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
HDLNJKFM_01394 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
HDLNJKFM_01395 0.0 pepN 3.4.11.2 E aminopeptidase
HDLNJKFM_01396 9.2e-113 phoU P Plays a role in the regulation of phosphate uptake
HDLNJKFM_01397 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDLNJKFM_01398 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDLNJKFM_01399 2.9e-154 pstA P phosphate transport system permease
HDLNJKFM_01400 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
HDLNJKFM_01401 3.3e-158 pstS P phosphate
HDLNJKFM_01402 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HDLNJKFM_01403 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HDLNJKFM_01404 1.9e-43 yktA S Belongs to the UPF0223 family
HDLNJKFM_01405 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDLNJKFM_01406 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDLNJKFM_01407 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDLNJKFM_01408 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
HDLNJKFM_01409 5.4e-95 XK27_04775 S hemerythrin HHE cation binding domain
HDLNJKFM_01410 6.3e-32 M1-755 P Hemerythrin HHE cation binding domain protein
HDLNJKFM_01411 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
HDLNJKFM_01412 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDLNJKFM_01413 1.7e-134 S haloacid dehalogenase-like hydrolase
HDLNJKFM_01414 1.7e-240 metY 2.5.1.49 E o-acetylhomoserine
HDLNJKFM_01415 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDLNJKFM_01416 3.4e-239 agcS E (Alanine) symporter
HDLNJKFM_01417 2.9e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDLNJKFM_01418 7.6e-233 L Transposase
HDLNJKFM_01419 1.6e-103 yfiF3 K sequence-specific DNA binding
HDLNJKFM_01420 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
HDLNJKFM_01421 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
HDLNJKFM_01423 2.3e-20 yecS P amino acid transport
HDLNJKFM_01424 1.4e-62 yecS P ABC transporter (Permease
HDLNJKFM_01425 6.1e-266 dtpT E transporter
HDLNJKFM_01426 8.1e-48 nylA 3.5.1.4 J Belongs to the amidase family
HDLNJKFM_01427 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDLNJKFM_01428 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDLNJKFM_01429 9.5e-32 csm6 S Psort location Cytoplasmic, score
HDLNJKFM_01431 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
HDLNJKFM_01432 5.2e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
HDLNJKFM_01433 1.6e-117 csm3 L RAMP superfamily
HDLNJKFM_01434 3.6e-42 csm2 L Csm2 Type III-A
HDLNJKFM_01435 0.0 csm1 S CRISPR-associated protein Csm1 family
HDLNJKFM_01436 1.2e-132 cas6 S CRISPR-associated endoribonuclease Cas6
HDLNJKFM_01437 1.5e-36 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLNJKFM_01438 4e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLNJKFM_01439 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDLNJKFM_01440 1.5e-149 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HDLNJKFM_01441 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
HDLNJKFM_01442 6.4e-54 S TraX protein
HDLNJKFM_01444 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HDLNJKFM_01446 6.3e-12 dinF V Mate efflux family protein
HDLNJKFM_01447 8.8e-55 dinF V Mate efflux family protein
HDLNJKFM_01448 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
HDLNJKFM_01449 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
HDLNJKFM_01450 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
HDLNJKFM_01451 2.6e-143 2.4.2.3 F Phosphorylase superfamily
HDLNJKFM_01454 1.7e-78 S Alpha/beta hydrolase of unknown function (DUF915)
HDLNJKFM_01455 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
HDLNJKFM_01456 6e-08 S Hydrolases of the alpha beta superfamily
HDLNJKFM_01457 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
HDLNJKFM_01458 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HDLNJKFM_01459 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HDLNJKFM_01460 3.1e-159 czcD P cation diffusion facilitator family transporter
HDLNJKFM_01461 9e-98 K Transcriptional regulator, TetR family
HDLNJKFM_01462 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HDLNJKFM_01463 1.3e-115 V ABC transporter (Permease
HDLNJKFM_01464 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDLNJKFM_01465 1.2e-88 adk 2.7.4.3 F topology modulation protein
HDLNJKFM_01466 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDLNJKFM_01467 5e-84 L Transposase
HDLNJKFM_01471 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
HDLNJKFM_01473 2.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HDLNJKFM_01474 1.8e-51 amd 3.5.1.47 E Peptidase dimerisation domain
HDLNJKFM_01475 7.9e-41 L COG1943 Transposase and inactivated derivatives
HDLNJKFM_01476 1.3e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDLNJKFM_01477 3.6e-42 K Cold-Shock Protein
HDLNJKFM_01478 9.3e-32 cspD K Cold shock protein domain
HDLNJKFM_01479 1.7e-25
HDLNJKFM_01481 7.1e-28 L transposase activity
HDLNJKFM_01482 3.9e-122 L Transposase
HDLNJKFM_01483 1.2e-165 L integrase core domain
HDLNJKFM_01484 4.1e-181 L Transposase
HDLNJKFM_01485 2.3e-114 L PFAM Integrase, catalytic core
HDLNJKFM_01486 1.9e-33 L PFAM Integrase, catalytic core
HDLNJKFM_01487 2.2e-244 cps1C S Polysaccharide biosynthesis protein
HDLNJKFM_01488 4.2e-90 2.7.8.12 GT2 M Glycosyltransferase like family 2
HDLNJKFM_01489 4.4e-121 L Transposase DDE domain
HDLNJKFM_01490 8.8e-91 2.7.8.12 GT2 S Glycosyltransferase like family 2
HDLNJKFM_01491 1.8e-139 L Integrase core domain
HDLNJKFM_01492 6.5e-15 L Transposase
HDLNJKFM_01493 6e-123 tnp L DDE domain
HDLNJKFM_01494 9e-09 rgpAc GT4 M group 1 family protein
HDLNJKFM_01495 7.5e-258 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HDLNJKFM_01496 1.1e-117 cpsD D COG0489 ATPases involved in chromosome partitioning
HDLNJKFM_01497 4.7e-107 cps4C M biosynthesis protein
HDLNJKFM_01498 3.9e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
HDLNJKFM_01499 1.6e-253 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
HDLNJKFM_01500 6.9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
HDLNJKFM_01501 5.8e-110 yfeJ 6.3.5.2 F glutamine amidotransferase
HDLNJKFM_01502 7.3e-41 clcA_2 P chloride
HDLNJKFM_01503 3.8e-42 clcA_2 P chloride channel
HDLNJKFM_01504 4.4e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HDLNJKFM_01505 8.1e-41 S Protein of unknown function (DUF1697)
HDLNJKFM_01506 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HDLNJKFM_01507 5e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDLNJKFM_01509 6.1e-22 V Glucan-binding protein C
HDLNJKFM_01510 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
HDLNJKFM_01511 1.5e-274 pepV 3.5.1.18 E Dipeptidase
HDLNJKFM_01512 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HDLNJKFM_01513 5.3e-86 XK27_03610 K Gnat family
HDLNJKFM_01514 2.3e-33 L Transposase
HDLNJKFM_01515 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDLNJKFM_01516 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDLNJKFM_01517 2.3e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDLNJKFM_01518 2.8e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDLNJKFM_01519 2.8e-18 M LysM domain
HDLNJKFM_01520 2.9e-90 ebsA S Family of unknown function (DUF5322)
HDLNJKFM_01521 4.2e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDLNJKFM_01522 4.3e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDLNJKFM_01523 4.5e-222 G COG0457 FOG TPR repeat
HDLNJKFM_01524 6.2e-176 yubA S permease
HDLNJKFM_01525 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
HDLNJKFM_01526 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HDLNJKFM_01527 2.5e-124 ftsE D cell division ATP-binding protein FtsE
HDLNJKFM_01528 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDLNJKFM_01529 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HDLNJKFM_01530 1e-181 yjjH S Calcineurin-like phosphoesterase
HDLNJKFM_01531 3.3e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HDLNJKFM_01532 0.0 pacL 3.6.3.8 P cation transport ATPase
HDLNJKFM_01533 3.4e-67 ywiB S Domain of unknown function (DUF1934)
HDLNJKFM_01534 1.4e-50 XK27_00115 2.3.1.128 K acetyltransferase
HDLNJKFM_01535 9.2e-147 yidA S hydrolases of the HAD superfamily
HDLNJKFM_01536 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
HDLNJKFM_01537 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
HDLNJKFM_01538 1.5e-247 vicK 2.7.13.3 T Histidine kinase
HDLNJKFM_01539 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLNJKFM_01540 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLNJKFM_01541 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
HDLNJKFM_01542 8e-115 gltJ P ABC transporter (Permease
HDLNJKFM_01543 2.5e-110 tcyB_2 P ABC transporter (permease)
HDLNJKFM_01544 1.1e-142 endA F DNA RNA non-specific endonuclease
HDLNJKFM_01545 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
HDLNJKFM_01546 3.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDLNJKFM_01548 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLNJKFM_01549 2.8e-131 G Domain of unknown function (DUF4832)
HDLNJKFM_01550 1.6e-33 P VTC domain
HDLNJKFM_01551 3.9e-47 P VTC domain
HDLNJKFM_01552 4.1e-218 cotH M CotH kinase protein
HDLNJKFM_01553 3.1e-185 pelG M Putative exopolysaccharide Exporter (EPS-E)
HDLNJKFM_01554 1.3e-276 pelF GT4 M Domain of unknown function (DUF3492)
HDLNJKFM_01555 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HDLNJKFM_01556 4.6e-139
HDLNJKFM_01557 4.2e-194 5.1.3.2 GM Psort location CytoplasmicMembrane, score
HDLNJKFM_01558 8.4e-42 5.1.3.2 GM Psort location CytoplasmicMembrane, score
HDLNJKFM_01559 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDLNJKFM_01560 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDLNJKFM_01561 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDLNJKFM_01562 3.9e-87 ytsP 1.8.4.14 T GAF domain-containing protein
HDLNJKFM_01563 7.1e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDLNJKFM_01564 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
HDLNJKFM_01566 3.4e-233 L Transposase
HDLNJKFM_01568 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDLNJKFM_01569 3.4e-217 XK27_05110 P chloride
HDLNJKFM_01570 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
HDLNJKFM_01571 1.9e-281 clcA P Chloride transporter, ClC family
HDLNJKFM_01572 1e-75 fld C Flavodoxin
HDLNJKFM_01573 3.3e-14 XK27_08880
HDLNJKFM_01574 1.1e-124 XK27_08875 O Zinc-dependent metalloprotease
HDLNJKFM_01575 6e-151 estA CE1 S Putative esterase
HDLNJKFM_01576 6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDLNJKFM_01577 1.2e-135 XK27_08845 S abc transporter atp-binding protein
HDLNJKFM_01578 8.9e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
HDLNJKFM_01579 1.1e-173 XK27_08835 S ABC transporter substrate binding protein
HDLNJKFM_01580 3.2e-17 S Domain of unknown function (DUF4649)
HDLNJKFM_01581 1.1e-27 Q the current gene model (or a revised gene model) may contain a frame shift
HDLNJKFM_01582 1.1e-27 Q the current gene model (or a revised gene model) may contain a frame shift
HDLNJKFM_01583 7e-43 L Transposase
HDLNJKFM_01584 1.7e-48 adk 2.7.4.3 F topology modulation protein
HDLNJKFM_01592 1.6e-42 hsdM 2.1.1.72 V type I restriction-modification system
HDLNJKFM_01593 9.6e-43 hsdM 2.1.1.72 V type I restriction-modification system
HDLNJKFM_01594 9.8e-176 EGP Major Facilitator Superfamily
HDLNJKFM_01595 5.5e-258 I radical SAM domain protein
HDLNJKFM_01597 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HDLNJKFM_01598 1.4e-150 L Integrase core domain protein
HDLNJKFM_01599 1.8e-87 L transposase activity
HDLNJKFM_01601 2.8e-85
HDLNJKFM_01602 0.0 sbcC L ATPase involved in DNA repair
HDLNJKFM_01603 1.7e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDLNJKFM_01604 0.0 lacL 3.2.1.23 G -beta-galactosidase
HDLNJKFM_01605 0.0 lacS G transporter
HDLNJKFM_01606 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDLNJKFM_01607 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLNJKFM_01608 7.8e-285 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
HDLNJKFM_01609 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDLNJKFM_01610 2.3e-184 galR K Transcriptional regulator
HDLNJKFM_01611 2.7e-08 L Integrase core domain protein
HDLNJKFM_01612 4.6e-25 L transposition
HDLNJKFM_01613 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HDLNJKFM_01614 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
HDLNJKFM_01615 5.2e-99 V abc transporter atp-binding protein
HDLNJKFM_01616 1.1e-40 V abc transporter atp-binding protein
HDLNJKFM_01617 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
HDLNJKFM_01618 4.6e-73 L Transposase
HDLNJKFM_01619 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDLNJKFM_01620 1.1e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HDLNJKFM_01621 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDLNJKFM_01622 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDLNJKFM_01625 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDLNJKFM_01626 2.9e-174 vraS 2.7.13.3 T Histidine kinase
HDLNJKFM_01627 9.1e-119 yvqF KT membrane
HDLNJKFM_01628 2.9e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
HDLNJKFM_01629 9e-133 stp 3.1.3.16 T phosphatase
HDLNJKFM_01630 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDLNJKFM_01631 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDLNJKFM_01632 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDLNJKFM_01633 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
HDLNJKFM_01634 2.6e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HDLNJKFM_01635 4.1e-211 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDLNJKFM_01636 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
HDLNJKFM_01637 5.3e-147 supH S overlaps another CDS with the same product name
HDLNJKFM_01638 8.6e-63 yvoA_1 K Transcriptional
HDLNJKFM_01639 9.8e-121 skfE V abc transporter atp-binding protein
HDLNJKFM_01640 9.6e-133 V ATPase activity
HDLNJKFM_01641 4.3e-172 oppF P Belongs to the ABC transporter superfamily
HDLNJKFM_01642 2.2e-204 oppD P Belongs to the ABC transporter superfamily
HDLNJKFM_01643 4.1e-167 amiD P ABC transporter (Permease
HDLNJKFM_01644 1.1e-270 amiC P ABC transporter (Permease
HDLNJKFM_01645 0.0 amiA E ABC transporter, substrate-binding protein, family 5
HDLNJKFM_01646 1.2e-24 oppF P Belongs to the ABC transporter superfamily
HDLNJKFM_01647 2.3e-23 oppF P Belongs to the ABC transporter superfamily
HDLNJKFM_01648 1.4e-40 tatD L Hydrolase, tatd
HDLNJKFM_01649 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
HDLNJKFM_01650 1e-110 L Integrase core domain protein
HDLNJKFM_01651 1.1e-23 L transposase activity
HDLNJKFM_01652 8.9e-18 L transposase activity
HDLNJKFM_01653 5.9e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HDLNJKFM_01654 1.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HDLNJKFM_01655 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDLNJKFM_01656 2.1e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
HDLNJKFM_01657 7.6e-103 yjbK S Adenylate cyclase
HDLNJKFM_01658 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDLNJKFM_01659 4.1e-206 iscS 2.8.1.7 E Cysteine desulfurase
HDLNJKFM_01660 9e-59 XK27_04120 S Putative amino acid metabolism
HDLNJKFM_01661 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDLNJKFM_01662 1.6e-131 puuD T peptidase C26
HDLNJKFM_01663 6.2e-120 radC E Belongs to the UPF0758 family
HDLNJKFM_01664 0.0 rgpF M Rhamnan synthesis protein F
HDLNJKFM_01665 3.4e-194 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HDLNJKFM_01666 3.3e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDLNJKFM_01667 1.4e-142 rgpC GM Transport permease protein
HDLNJKFM_01668 6.3e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
HDLNJKFM_01669 7.7e-224 rgpA GT4 M Domain of unknown function (DUF1972)
HDLNJKFM_01670 7.9e-139 S Predicted membrane protein (DUF2142)
HDLNJKFM_01671 2.3e-187 tagF 2.7.8.12 M Glycosyl transferase, family 2
HDLNJKFM_01672 7.3e-215 amrA S polysaccharide biosynthetic process
HDLNJKFM_01673 1.5e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
HDLNJKFM_01674 1.9e-124 ycbB S Glycosyl transferase family 2
HDLNJKFM_01675 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDLNJKFM_01676 3.2e-245
HDLNJKFM_01680 2.6e-10
HDLNJKFM_01683 1e-199 yjbB G Permeases of the major facilitator superfamily
HDLNJKFM_01684 3.6e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
HDLNJKFM_01685 1.6e-97 thiT S Thiamine transporter
HDLNJKFM_01686 2.5e-62 yjqA S Bacterial PH domain
HDLNJKFM_01687 1e-149 corA P CorA-like protein
HDLNJKFM_01688 1e-250 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDLNJKFM_01689 1e-41 yazA L endonuclease containing a URI domain
HDLNJKFM_01690 6e-140 yabB 2.1.1.223 L Methyltransferase
HDLNJKFM_01691 7.1e-137 nodB3 G deacetylase
HDLNJKFM_01692 3.7e-142 plsC 2.3.1.51 I Acyltransferase
HDLNJKFM_01693 7e-95 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
HDLNJKFM_01694 0.0 comEC S Competence protein ComEC
HDLNJKFM_01695 2.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDLNJKFM_01696 1.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
HDLNJKFM_01697 3.3e-231 ytoI K transcriptional regulator containing CBS domains
HDLNJKFM_01698 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
HDLNJKFM_01699 7.4e-164 rbn E Belongs to the UPF0761 family
HDLNJKFM_01700 1.3e-85 ccl S cog cog4708
HDLNJKFM_01701 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDLNJKFM_01702 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HDLNJKFM_01703 1.7e-119 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
HDLNJKFM_01704 2.1e-74 S QueT transporter
HDLNJKFM_01705 1.3e-156 xth 3.1.11.2 L exodeoxyribonuclease III
HDLNJKFM_01706 2.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
HDLNJKFM_01707 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDLNJKFM_01708 4.1e-37 ylqC L Belongs to the UPF0109 family
HDLNJKFM_01709 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDLNJKFM_01710 6.8e-17 ydaO E amino acid
HDLNJKFM_01711 2.8e-163 ydaO E amino acid
HDLNJKFM_01712 5.7e-132 ydaO E amino acid
HDLNJKFM_01713 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
HDLNJKFM_01714 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HDLNJKFM_01715 3e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
HDLNJKFM_01716 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDLNJKFM_01717 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HDLNJKFM_01718 7.8e-171 murB 1.3.1.98 M cell wall formation
HDLNJKFM_01719 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDLNJKFM_01720 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
HDLNJKFM_01721 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
HDLNJKFM_01722 2.3e-206 potD P spermidine putrescine ABC transporter
HDLNJKFM_01723 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
HDLNJKFM_01724 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
HDLNJKFM_01725 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
HDLNJKFM_01726 5.1e-96 GK ROK family
HDLNJKFM_01727 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDLNJKFM_01728 1.5e-103 wecD M Acetyltransferase GNAT family
HDLNJKFM_01729 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDLNJKFM_01730 1e-54 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
HDLNJKFM_01731 3.2e-59 arsC 1.20.4.1 P Belongs to the ArsC family
HDLNJKFM_01733 5e-55 lrgA S Effector of murein hydrolase LrgA
HDLNJKFM_01734 2.2e-117 lrgB M effector of murein hydrolase
HDLNJKFM_01735 1.3e-108 3.1.3.18 S IA, variant 1
HDLNJKFM_01736 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDLNJKFM_01737 1.6e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDLNJKFM_01738 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
HDLNJKFM_01739 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HDLNJKFM_01740 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLNJKFM_01741 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HDLNJKFM_01742 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
HDLNJKFM_01744 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
HDLNJKFM_01746 3e-37 ycaO O OsmC-like protein
HDLNJKFM_01747 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
HDLNJKFM_01750 1.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDLNJKFM_01752 3.7e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDLNJKFM_01753 1.1e-16 XK27_00735
HDLNJKFM_01754 6.3e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
HDLNJKFM_01755 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
HDLNJKFM_01756 3.4e-32 S CAAX amino terminal protease family protein
HDLNJKFM_01758 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDLNJKFM_01759 1.1e-83 mutT 3.6.1.55 F Nudix family
HDLNJKFM_01760 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
HDLNJKFM_01761 9.4e-136 ET ABC transporter
HDLNJKFM_01762 2.6e-200 arcT 2.6.1.1 E Aminotransferase
HDLNJKFM_01763 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
HDLNJKFM_01764 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDLNJKFM_01765 1.9e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDLNJKFM_01766 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDLNJKFM_01767 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDLNJKFM_01768 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
HDLNJKFM_01769 1.4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
HDLNJKFM_01770 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDLNJKFM_01771 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDLNJKFM_01772 3.9e-37 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HDLNJKFM_01773 8.6e-22 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
HDLNJKFM_01774 1.2e-62 bioY S biotin transmembrane transporter activity
HDLNJKFM_01775 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
HDLNJKFM_01776 2.1e-137 proV E abc transporter atp-binding protein
HDLNJKFM_01777 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
HDLNJKFM_01778 3e-111 proWZ P ABC transporter (Permease
HDLNJKFM_01779 1.4e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
HDLNJKFM_01780 5.4e-206 S Protein of unknown function (DUF917)
HDLNJKFM_01781 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HDLNJKFM_01782 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
HDLNJKFM_01783 1.7e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HDLNJKFM_01784 2e-192 desK 2.7.13.3 T Histidine kinase
HDLNJKFM_01785 4.5e-132 yvfS V ABC-2 type transporter
HDLNJKFM_01786 1.5e-158 XK27_09825 V abc transporter atp-binding protein
HDLNJKFM_01790 3.3e-212 EGP Major facilitator Superfamily
HDLNJKFM_01791 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
HDLNJKFM_01792 7.9e-152 mutR K Transcriptional activator, Rgg GadR MutR family
HDLNJKFM_01793 4.6e-42 3.6.1.55 F NUDIX domain
HDLNJKFM_01795 3.7e-122 S An automated process has identified a potential problem with this gene model
HDLNJKFM_01796 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
HDLNJKFM_01797 1.4e-15 liaI KT membrane
HDLNJKFM_01798 2.6e-30 liaI KT membrane
HDLNJKFM_01799 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
HDLNJKFM_01800 0.0 V ABC transporter (permease)
HDLNJKFM_01801 1.9e-133 macB2 V ABC transporter, ATP-binding protein
HDLNJKFM_01802 6.2e-166 T Histidine kinase
HDLNJKFM_01803 3.9e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HDLNJKFM_01804 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDLNJKFM_01806 1.5e-69 pbuX F xanthine permease
HDLNJKFM_01807 1.1e-119 pbuX F xanthine permease
HDLNJKFM_01808 1.5e-247 norM V Multidrug efflux pump
HDLNJKFM_01809 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDLNJKFM_01810 3.3e-234 brnQ E Component of the transport system for branched-chain amino acids
HDLNJKFM_01811 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDLNJKFM_01812 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDLNJKFM_01813 4.8e-25 csbD K CsbD-like
HDLNJKFM_01814 6.2e-228 yfnA E amino acid
HDLNJKFM_01815 5.1e-110 XK27_02070 S nitroreductase
HDLNJKFM_01816 3.7e-154 1.13.11.2 S glyoxalase
HDLNJKFM_01817 5.6e-77 ywnA K Transcriptional regulator
HDLNJKFM_01818 8.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
HDLNJKFM_01819 5.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDLNJKFM_01820 1.4e-110 drgA C Nitroreductase
HDLNJKFM_01821 2.3e-108 yoaK S Protein of unknown function (DUF1275)
HDLNJKFM_01822 6.8e-161 yvgN C reductase
HDLNJKFM_01823 7.3e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDLNJKFM_01824 2.4e-09
HDLNJKFM_01825 1.6e-140 S Abortive infection C-terminus
HDLNJKFM_01826 0.0 L DEAD-like helicases superfamily
HDLNJKFM_01827 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HDLNJKFM_01828 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
HDLNJKFM_01830 1.1e-37 BP1961 P nitric oxide dioxygenase activity
HDLNJKFM_01831 4.8e-55 K response regulator
HDLNJKFM_01832 1.8e-70 S Signal peptide protein, YSIRK family
HDLNJKFM_01834 2.2e-60
HDLNJKFM_01835 7e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDLNJKFM_01836 1.3e-130
HDLNJKFM_01837 2.8e-10 IQ PFAM AMP-dependent synthetase and ligase
HDLNJKFM_01838 1.6e-77 sigH K DNA-templated transcription, initiation
HDLNJKFM_01839 6e-149 ykuT M mechanosensitive ion channel
HDLNJKFM_01840 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDLNJKFM_01841 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDLNJKFM_01842 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDLNJKFM_01843 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
HDLNJKFM_01844 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
HDLNJKFM_01845 9.1e-178 prmA J Ribosomal protein L11 methyltransferase
HDLNJKFM_01846 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDLNJKFM_01847 1.4e-42 F nucleotide catabolic process
HDLNJKFM_01848 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDLNJKFM_01849 2.4e-83 nrdI F Belongs to the NrdI family
HDLNJKFM_01850 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDLNJKFM_01851 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDLNJKFM_01852 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HDLNJKFM_01853 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HDLNJKFM_01854 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HDLNJKFM_01855 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
HDLNJKFM_01856 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HDLNJKFM_01857 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDLNJKFM_01858 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HDLNJKFM_01859 6.5e-202 yhjX P Major Facilitator
HDLNJKFM_01860 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDLNJKFM_01861 5e-94 V VanZ like family
HDLNJKFM_01863 1e-123 glnQ E abc transporter atp-binding protein
HDLNJKFM_01864 5.3e-276 glnP P ABC transporter
HDLNJKFM_01865 2e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDLNJKFM_01866 1.2e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDLNJKFM_01867 1.8e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
HDLNJKFM_01868 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HDLNJKFM_01869 6.3e-235 sufD O assembly protein SufD
HDLNJKFM_01870 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDLNJKFM_01871 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
HDLNJKFM_01872 3.5e-274 sufB O assembly protein SufB
HDLNJKFM_01873 2.4e-19 oppA E ABC transporter substrate-binding protein
HDLNJKFM_01874 1.4e-133 oppA E ABC transporter substrate-binding protein
HDLNJKFM_01875 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLNJKFM_01876 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLNJKFM_01877 5.4e-46 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLNJKFM_01878 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDLNJKFM_01879 8e-28 oppD P Belongs to the ABC transporter superfamily
HDLNJKFM_01880 2.5e-32 oppD P Belongs to the ABC transporter superfamily
HDLNJKFM_01881 4.8e-67 oppD P Belongs to the ABC transporter superfamily
HDLNJKFM_01882 1.7e-30 oppD P Belongs to the ABC transporter superfamily
HDLNJKFM_01883 3.4e-169 oppF P Belongs to the ABC transporter superfamily
HDLNJKFM_01886 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDLNJKFM_01887 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDLNJKFM_01888 1.9e-223 EGP Major facilitator Superfamily
HDLNJKFM_01889 3.1e-72 adcR K transcriptional
HDLNJKFM_01890 6.4e-136 adcC P ABC transporter, ATP-binding protein
HDLNJKFM_01891 1.7e-129 adcB P ABC transporter (Permease
HDLNJKFM_01892 6.2e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HDLNJKFM_01893 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
HDLNJKFM_01894 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
HDLNJKFM_01895 1.1e-81 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDLNJKFM_01896 4.2e-149 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
HDLNJKFM_01897 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
HDLNJKFM_01898 1.9e-127 yeeN K transcriptional regulatory protein
HDLNJKFM_01899 9.8e-50 yajC U protein transport
HDLNJKFM_01900 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDLNJKFM_01901 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
HDLNJKFM_01902 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HDLNJKFM_01903 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDLNJKFM_01904 0.0 WQ51_06230 S ABC transporter substrate binding protein
HDLNJKFM_01905 5.2e-142 cmpC S abc transporter atp-binding protein
HDLNJKFM_01906 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDLNJKFM_01907 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDLNJKFM_01908 4.4e-37 L Transposase
HDLNJKFM_01909 3.2e-17 L transposase activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)