ORF_ID e_value Gene_name EC_number CAZy COGs Description
MBEFOJME_00001 2e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
MBEFOJME_00002 2.4e-144 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
MBEFOJME_00003 0.0 yjcE P NhaP-type Na H and K H antiporters
MBEFOJME_00005 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
MBEFOJME_00006 1.3e-184 yhcC S radical SAM protein
MBEFOJME_00007 2.2e-196 ylbL T Belongs to the peptidase S16 family
MBEFOJME_00008 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MBEFOJME_00009 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
MBEFOJME_00010 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MBEFOJME_00011 1.9e-09 S Protein of unknown function (DUF4059)
MBEFOJME_00012 4.5e-132 tcyN 3.6.3.21 E abc transporter atp-binding protein
MBEFOJME_00013 1e-162 yxeN P ABC transporter (Permease
MBEFOJME_00014 5.7e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MBEFOJME_00016 3.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MBEFOJME_00017 0.0 pflB 2.3.1.54 C formate acetyltransferase'
MBEFOJME_00018 5.2e-147 cah 4.2.1.1 P carbonic anhydrase
MBEFOJME_00019 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MBEFOJME_00020 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
MBEFOJME_00021 2.9e-87 D nuclear chromosome segregation
MBEFOJME_00022 1.5e-127 ybbM S transport system, permease component
MBEFOJME_00023 1.2e-117 ybbL S abc transporter atp-binding protein
MBEFOJME_00024 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
MBEFOJME_00025 4.6e-140 cppA E CppA N-terminal
MBEFOJME_00026 5e-44 V CAAX protease self-immunity
MBEFOJME_00027 2.3e-164 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MBEFOJME_00028 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MBEFOJME_00031 3e-47 spiA K sequence-specific DNA binding
MBEFOJME_00032 2.9e-28 blpT
MBEFOJME_00033 6.7e-98 blpT
MBEFOJME_00039 6.7e-26 S Bacteriocin class II with double-glycine leader peptide
MBEFOJME_00043 7.4e-135 agrA KT phosphorelay signal transduction system
MBEFOJME_00044 3.4e-239 blpH 2.7.13.3 T protein histidine kinase activity
MBEFOJME_00046 7.3e-237 mesE M Transport protein ComB
MBEFOJME_00047 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MBEFOJME_00048 0.0 mdlB V abc transporter atp-binding protein
MBEFOJME_00049 0.0 mdlA V abc transporter atp-binding protein
MBEFOJME_00051 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
MBEFOJME_00052 3e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MBEFOJME_00053 1e-64 yutD J protein conserved in bacteria
MBEFOJME_00054 2.1e-268 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MBEFOJME_00056 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MBEFOJME_00057 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MBEFOJME_00058 0.0 ftsI 3.4.16.4 M penicillin-binding protein
MBEFOJME_00059 4.3e-47 ftsL D cell division protein FtsL
MBEFOJME_00060 3e-157 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MBEFOJME_00061 1.6e-65
MBEFOJME_00062 7.4e-27
MBEFOJME_00063 2.6e-30
MBEFOJME_00065 8.7e-33 yhaI J Protein of unknown function (DUF805)
MBEFOJME_00066 2e-22 D nuclear chromosome segregation
MBEFOJME_00067 7.6e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MBEFOJME_00068 4.9e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MBEFOJME_00069 6.4e-285 XK27_00765
MBEFOJME_00070 1.2e-106 ecsA_2 V abc transporter atp-binding protein
MBEFOJME_00071 5.2e-125 S Protein of unknown function (DUF554)
MBEFOJME_00072 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MBEFOJME_00073 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MBEFOJME_00074 2.6e-121 liaI S membrane
MBEFOJME_00075 5.2e-75 XK27_02470 K LytTr DNA-binding domain
MBEFOJME_00076 3.6e-66 KT response to antibiotic
MBEFOJME_00077 5.2e-81 yebC M Membrane
MBEFOJME_00078 2.9e-18 yebC M Membrane
MBEFOJME_00079 8.1e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
MBEFOJME_00080 3.8e-173 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MBEFOJME_00082 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MBEFOJME_00083 4e-185 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MBEFOJME_00084 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MBEFOJME_00085 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MBEFOJME_00086 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MBEFOJME_00087 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MBEFOJME_00089 3e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
MBEFOJME_00090 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
MBEFOJME_00091 0.0 scrA 2.7.1.208, 2.7.1.211 G pts system
MBEFOJME_00092 1.2e-290 scrB 3.2.1.26 GH32 G invertase
MBEFOJME_00093 7.5e-180 scrR K Transcriptional
MBEFOJME_00094 2.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MBEFOJME_00095 3.4e-62 yqhY S protein conserved in bacteria
MBEFOJME_00096 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MBEFOJME_00097 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
MBEFOJME_00098 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
MBEFOJME_00100 8e-44 V 'abc transporter, ATP-binding protein
MBEFOJME_00101 1e-58 V 'abc transporter, ATP-binding protein
MBEFOJME_00103 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MBEFOJME_00104 2e-169 corA P COG0598 Mg2 and Co2 transporters
MBEFOJME_00105 3.1e-124 XK27_01040 S Pfam PF06570
MBEFOJME_00107 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MBEFOJME_00108 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MBEFOJME_00109 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
MBEFOJME_00110 9.5e-42 XK27_05745
MBEFOJME_00111 2.5e-230 mutY L A G-specific adenine glycosylase
MBEFOJME_00116 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MBEFOJME_00117 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MBEFOJME_00118 1e-93 cvpA S toxin biosynthetic process
MBEFOJME_00119 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MBEFOJME_00120 4.7e-160 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MBEFOJME_00121 1.3e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MBEFOJME_00122 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MBEFOJME_00123 2e-47 azlD E branched-chain amino acid
MBEFOJME_00124 1.8e-114 azlC E AzlC protein
MBEFOJME_00125 1.1e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MBEFOJME_00126 8.2e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MBEFOJME_00127 5.6e-121 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
MBEFOJME_00128 2.5e-33 ykzG S Belongs to the UPF0356 family
MBEFOJME_00129 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MBEFOJME_00130 2.7e-40 pscB M CHAP domain protein
MBEFOJME_00131 1.5e-263 glnA 6.3.1.2 E glutamine synthetase
MBEFOJME_00132 8.5e-63 glnR K Transcriptional regulator
MBEFOJME_00133 1.3e-87 S Fusaric acid resistance protein-like
MBEFOJME_00134 9.9e-19 S Domain of unknown function (DUF4649)
MBEFOJME_00135 1.8e-56 amd 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MBEFOJME_00136 1.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MBEFOJME_00137 1e-84
MBEFOJME_00138 1.6e-77 sigH K DNA-templated transcription, initiation
MBEFOJME_00139 3e-148 ykuT M mechanosensitive ion channel
MBEFOJME_00140 1.4e-218 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MBEFOJME_00141 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MBEFOJME_00142 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MBEFOJME_00143 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
MBEFOJME_00144 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
MBEFOJME_00145 2e-177 prmA J Ribosomal protein L11 methyltransferase
MBEFOJME_00146 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MBEFOJME_00147 1.4e-42 F nucleotide catabolic process
MBEFOJME_00148 5.4e-139 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MBEFOJME_00149 7.7e-140 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MBEFOJME_00150 2.3e-51 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MBEFOJME_00151 1.8e-83 nrdI F Belongs to the NrdI family
MBEFOJME_00152 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MBEFOJME_00153 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MBEFOJME_00154 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MBEFOJME_00155 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MBEFOJME_00156 5.6e-59 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MBEFOJME_00157 1.1e-45 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
MBEFOJME_00158 2.3e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MBEFOJME_00159 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MBEFOJME_00160 1.2e-112 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
MBEFOJME_00161 9.3e-201 yhjX P Major Facilitator
MBEFOJME_00162 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MBEFOJME_00163 5e-94 V VanZ like family
MBEFOJME_00166 1e-123 glnQ E abc transporter atp-binding protein
MBEFOJME_00167 2.9e-274 glnP P ABC transporter
MBEFOJME_00168 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MBEFOJME_00169 2.3e-136 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MBEFOJME_00170 1.1e-185 tagO 2.7.8.33, 2.7.8.35 M transferase
MBEFOJME_00171 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MBEFOJME_00172 6.3e-235 sufD O assembly protein SufD
MBEFOJME_00173 2.3e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MBEFOJME_00174 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
MBEFOJME_00175 2.2e-273 sufB O assembly protein SufB
MBEFOJME_00176 7e-10 oppA E ABC transporter substrate-binding protein
MBEFOJME_00177 2e-138 oppA E ABC transporter substrate-binding protein
MBEFOJME_00178 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MBEFOJME_00179 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MBEFOJME_00180 1.7e-33 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MBEFOJME_00181 1.4e-38 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MBEFOJME_00182 3e-27 oppD P Belongs to the ABC transporter superfamily
MBEFOJME_00183 2.5e-32 oppD P Belongs to the ABC transporter superfamily
MBEFOJME_00184 1.7e-61 oppD P Belongs to the ABC transporter superfamily
MBEFOJME_00185 3.1e-43 oppD P Belongs to the ABC transporter superfamily
MBEFOJME_00186 7.5e-62 oppF P Belongs to the ABC transporter superfamily
MBEFOJME_00187 4.7e-64 oppF P Belongs to the ABC transporter superfamily
MBEFOJME_00190 1.9e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MBEFOJME_00191 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MBEFOJME_00192 1.9e-223 EGP Major facilitator Superfamily
MBEFOJME_00193 3.1e-72 adcR K transcriptional
MBEFOJME_00194 6.4e-136 adcC P ABC transporter, ATP-binding protein
MBEFOJME_00195 1.6e-127 adcB P ABC transporter (Permease
MBEFOJME_00196 1.4e-162 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MBEFOJME_00197 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
MBEFOJME_00198 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
MBEFOJME_00199 3.6e-106 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MBEFOJME_00200 6.8e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
MBEFOJME_00201 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
MBEFOJME_00202 1.9e-127 yeeN K transcriptional regulatory protein
MBEFOJME_00203 9.8e-50 yajC U protein transport
MBEFOJME_00204 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MBEFOJME_00205 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
MBEFOJME_00206 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MBEFOJME_00207 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MBEFOJME_00209 8.4e-205 rpsA 1.17.7.4 J ribosomal protein S1
MBEFOJME_00212 4.8e-16 S Protein of unknown function (DUF2969)
MBEFOJME_00213 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
MBEFOJME_00214 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MBEFOJME_00215 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MBEFOJME_00216 7.1e-102 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MBEFOJME_00217 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
MBEFOJME_00218 5.5e-29 S Domain of unknown function (DUF1912)
MBEFOJME_00219 4.4e-172 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
MBEFOJME_00220 1.9e-248 mmuP E amino acid
MBEFOJME_00221 3e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
MBEFOJME_00222 2e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MBEFOJME_00223 9.7e-22
MBEFOJME_00224 3.4e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MBEFOJME_00225 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MBEFOJME_00226 1.7e-218 mvaS 2.3.3.10 I synthase
MBEFOJME_00227 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MBEFOJME_00228 1e-25 K hmm pf08876
MBEFOJME_00229 1.5e-118 yqfA K protein, Hemolysin III
MBEFOJME_00230 1.2e-22 S Protein of unknown function (DUF3114)
MBEFOJME_00231 2.4e-161 S Protein of unknown function (DUF3114)
MBEFOJME_00232 3.6e-70 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MBEFOJME_00233 1.9e-48 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MBEFOJME_00234 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MBEFOJME_00236 4.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MBEFOJME_00237 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
MBEFOJME_00238 1.9e-11 U protein secretion
MBEFOJME_00239 2.3e-49 U protein secretion
MBEFOJME_00240 3.5e-07 U protein secretion
MBEFOJME_00242 2e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MBEFOJME_00243 2.5e-21
MBEFOJME_00244 4.5e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
MBEFOJME_00245 5.6e-253 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MBEFOJME_00246 2.6e-191 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MBEFOJME_00247 3.3e-178 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
MBEFOJME_00248 1.9e-172 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MBEFOJME_00249 1.7e-138 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MBEFOJME_00250 4.6e-105 GBS0088 J protein conserved in bacteria
MBEFOJME_00251 5.7e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MBEFOJME_00252 1.5e-45 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MBEFOJME_00253 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
MBEFOJME_00254 2.4e-217 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MBEFOJME_00255 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MBEFOJME_00256 7.5e-113 S VIT family
MBEFOJME_00257 4.1e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
MBEFOJME_00258 4.3e-22
MBEFOJME_00259 1e-195 yceA S Belongs to the UPF0176 family
MBEFOJME_00260 5.4e-122 sagI S ABC-2 type transporter
MBEFOJME_00261 1.1e-167 V ABC transporter
MBEFOJME_00262 6.2e-34 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MBEFOJME_00263 8.5e-173 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MBEFOJME_00264 1.3e-131 rr02 KT response regulator
MBEFOJME_00265 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
MBEFOJME_00266 3.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MBEFOJME_00267 6e-199 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MBEFOJME_00268 0.0 lmrA V abc transporter atp-binding protein
MBEFOJME_00269 0.0 mdlB V abc transporter atp-binding protein
MBEFOJME_00271 6.3e-28 L Transposase
MBEFOJME_00272 3.7e-106 L Transposase
MBEFOJME_00273 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MBEFOJME_00274 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MBEFOJME_00275 7.2e-239 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MBEFOJME_00276 5.1e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
MBEFOJME_00278 2.7e-61 divIC D Septum formation initiator
MBEFOJME_00279 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MBEFOJME_00280 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MBEFOJME_00281 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MBEFOJME_00282 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MBEFOJME_00283 1.1e-29 yyzM S Protein conserved in bacteria
MBEFOJME_00284 6.3e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MBEFOJME_00285 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MBEFOJME_00286 8.5e-134 parB K Belongs to the ParB family
MBEFOJME_00287 2.6e-193 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
MBEFOJME_00288 3.3e-86 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MBEFOJME_00289 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
MBEFOJME_00293 0.0 XK27_10405 S Bacterial membrane protein YfhO
MBEFOJME_00294 6.7e-306 ybiT S abc transporter atp-binding protein
MBEFOJME_00295 4.2e-153 yvjA S membrane
MBEFOJME_00296 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MBEFOJME_00297 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MBEFOJME_00298 7.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MBEFOJME_00299 4.7e-45 yaaA S S4 domain protein YaaA
MBEFOJME_00300 4.8e-134 ymfF S Peptidase M16
MBEFOJME_00301 1e-72 ymfF S Peptidase M16
MBEFOJME_00302 3.1e-242 ymfH S Peptidase M16
MBEFOJME_00303 6.3e-138 ymfM S sequence-specific DNA binding
MBEFOJME_00304 3.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MBEFOJME_00305 1.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MBEFOJME_00306 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MBEFOJME_00307 2e-138 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MBEFOJME_00308 5.3e-85 lytE M LysM domain protein
MBEFOJME_00309 1.5e-91 isaA GH23 M Immunodominant staphylococcal antigen A
MBEFOJME_00310 0.0 S Bacterial membrane protein, YfhO
MBEFOJME_00311 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MBEFOJME_00312 1.5e-77 F NUDIX domain
MBEFOJME_00313 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MBEFOJME_00314 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MBEFOJME_00315 3.9e-70 rplI J binds to the 23S rRNA
MBEFOJME_00316 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MBEFOJME_00317 8.2e-48 veg S Biofilm formation stimulator VEG
MBEFOJME_00318 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MBEFOJME_00319 2.7e-08
MBEFOJME_00320 4.8e-55 ypaA M Membrane
MBEFOJME_00321 6.4e-96 XK27_06935 K transcriptional regulator
MBEFOJME_00322 2.5e-160 XK27_06930 V domain protein
MBEFOJME_00323 1.8e-88 S Putative adhesin
MBEFOJME_00324 1.8e-19 XK27_06920 S Protein of unknown function (DUF1700)
MBEFOJME_00326 1.7e-23 K negative regulation of transcription, DNA-templated
MBEFOJME_00327 2.6e-18 K negative regulation of transcription, DNA-templated
MBEFOJME_00328 3.4e-13 nudL L hydrolase
MBEFOJME_00329 1.7e-96 nudL L hydrolase
MBEFOJME_00330 4.9e-12 K CsbD-like
MBEFOJME_00331 1.1e-71 M Protein conserved in bacteria
MBEFOJME_00332 1.8e-23 S Small integral membrane protein
MBEFOJME_00333 3.1e-101
MBEFOJME_00334 3.7e-27 S Membrane
MBEFOJME_00335 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MBEFOJME_00336 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MBEFOJME_00337 3e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MBEFOJME_00338 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MBEFOJME_00339 1.6e-21 S glycolate biosynthetic process
MBEFOJME_00340 1.5e-64 S phosphatase activity
MBEFOJME_00341 2e-157 rrmA 2.1.1.187 Q methyltransferase
MBEFOJME_00344 2.7e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MBEFOJME_00345 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MBEFOJME_00346 6.4e-37 yeeD O sulfur carrier activity
MBEFOJME_00347 5.6e-189 yeeE S Sulphur transport
MBEFOJME_00348 7.9e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MBEFOJME_00349 4.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MBEFOJME_00350 4.1e-09 S Domain of unknown function (DUF4651)
MBEFOJME_00351 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MBEFOJME_00352 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MBEFOJME_00353 3.3e-110 S CAAX amino terminal protease family protein
MBEFOJME_00355 5e-67 V CAAX protease self-immunity
MBEFOJME_00356 1.4e-33 V CAAX protease self-immunity
MBEFOJME_00357 8.8e-27 lanR K sequence-specific DNA binding
MBEFOJME_00358 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MBEFOJME_00359 5.9e-177 ytxK 2.1.1.72 L DNA methylase
MBEFOJME_00360 6.8e-13 comGF U Putative Competence protein ComGF
MBEFOJME_00361 4e-72 comGF U Competence protein ComGF
MBEFOJME_00362 1.4e-15 NU Type II secretory pathway pseudopilin
MBEFOJME_00363 4e-57 cglD NU Competence protein
MBEFOJME_00364 8.5e-43 comGC U Required for transformation and DNA binding
MBEFOJME_00365 1.8e-156 cglB U protein transport across the cell outer membrane
MBEFOJME_00366 2.1e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MBEFOJME_00367 2.9e-68 S cog cog4699
MBEFOJME_00368 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MBEFOJME_00369 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MBEFOJME_00370 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MBEFOJME_00371 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MBEFOJME_00372 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MBEFOJME_00373 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
MBEFOJME_00374 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
MBEFOJME_00375 4.4e-280 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MBEFOJME_00376 3.3e-11 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MBEFOJME_00377 1.7e-304 yloV S kinase related to dihydroxyacetone kinase
MBEFOJME_00378 1.4e-57 asp S cog cog1302
MBEFOJME_00379 9.3e-226 norN V Mate efflux family protein
MBEFOJME_00380 6.4e-279 thrC 4.2.3.1 E Threonine synthase
MBEFOJME_00381 3.8e-99 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MBEFOJME_00382 3.5e-76 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MBEFOJME_00383 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MBEFOJME_00384 1.4e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
MBEFOJME_00385 0.0 pepO 3.4.24.71 O Peptidase family M13
MBEFOJME_00386 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MBEFOJME_00387 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MBEFOJME_00388 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MBEFOJME_00389 1.4e-54 treB 2.7.1.201 G PTS System
MBEFOJME_00390 5.8e-21 treR K DNA-binding transcription factor activity
MBEFOJME_00391 8.6e-87 treR K trehalose operon
MBEFOJME_00392 5.7e-95 ywlG S Belongs to the UPF0340 family
MBEFOJME_00395 6.9e-242 yfjK F helicase superfamily c-terminal domain
MBEFOJME_00396 5.3e-34
MBEFOJME_00397 4.1e-215 dcm 2.1.1.37 H cytosine-specific methyltransferase
MBEFOJME_00398 1.1e-265
MBEFOJME_00399 1.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MBEFOJME_00400 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
MBEFOJME_00401 2.3e-76 atpF C ATP synthase F(0) sector subunit b
MBEFOJME_00402 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MBEFOJME_00403 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MBEFOJME_00404 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MBEFOJME_00405 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MBEFOJME_00406 5.2e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MBEFOJME_00407 6.8e-229 ftsW D Belongs to the SEDS family
MBEFOJME_00408 9.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MBEFOJME_00409 1.4e-136 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MBEFOJME_00410 2.8e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MBEFOJME_00411 5.4e-161 holB 2.7.7.7 L dna polymerase iii
MBEFOJME_00412 1.2e-135 yaaT S stage 0 sporulation protein
MBEFOJME_00413 9.5e-55 yabA L Involved in initiation control of chromosome replication
MBEFOJME_00414 4.6e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MBEFOJME_00415 6.8e-226 amt P Ammonium Transporter
MBEFOJME_00416 1.1e-53 glnB K Belongs to the P(II) protein family
MBEFOJME_00417 1.3e-103 mur1 NU mannosyl-glycoprotein
MBEFOJME_00418 5.8e-149 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
MBEFOJME_00419 7.7e-69 nptA P sodium-dependent phosphate transmembrane transporter activity
MBEFOJME_00420 2.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MBEFOJME_00421 4.9e-51
MBEFOJME_00422 2.2e-25
MBEFOJME_00423 3.9e-60
MBEFOJME_00424 6.1e-63 S membrane
MBEFOJME_00425 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MBEFOJME_00426 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MBEFOJME_00427 4.5e-39 ynzC S UPF0291 protein
MBEFOJME_00428 1.8e-254 cycA E permease
MBEFOJME_00429 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
MBEFOJME_00430 1.7e-70 pts33BCA G pts system
MBEFOJME_00431 1.1e-76 pts33BCA G pts system
MBEFOJME_00432 4.7e-68 pts33BCA G pts system
MBEFOJME_00433 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MBEFOJME_00438 1.8e-167 fhuR K transcriptional regulator (lysR family)
MBEFOJME_00439 8.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MBEFOJME_00440 5e-162 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MBEFOJME_00441 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MBEFOJME_00442 4.9e-227 pyrP F uracil Permease
MBEFOJME_00443 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MBEFOJME_00444 5.5e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
MBEFOJME_00445 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
MBEFOJME_00446 4.6e-132 2.1.1.223 S Putative SAM-dependent methyltransferase
MBEFOJME_00447 7.6e-21 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MBEFOJME_00448 6.9e-37 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MBEFOJME_00449 3.6e-35 V efflux transmembrane transporter activity
MBEFOJME_00450 1.7e-29 V efflux transmembrane transporter activity
MBEFOJME_00451 8.2e-28 ytrF V efflux transmembrane transporter activity
MBEFOJME_00452 8.2e-77 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MBEFOJME_00453 3e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MBEFOJME_00454 0.0 pepN 3.4.11.2 E aminopeptidase
MBEFOJME_00455 2.4e-113 phoU P Plays a role in the regulation of phosphate uptake
MBEFOJME_00456 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MBEFOJME_00457 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MBEFOJME_00458 1.2e-155 pstA P phosphate transport system permease
MBEFOJME_00459 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
MBEFOJME_00460 3.3e-158 pstS P phosphate
MBEFOJME_00461 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MBEFOJME_00462 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MBEFOJME_00463 1.9e-43 yktA S Belongs to the UPF0223 family
MBEFOJME_00464 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MBEFOJME_00465 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MBEFOJME_00466 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MBEFOJME_00467 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
MBEFOJME_00468 1.7e-96 XK27_04775 S hemerythrin HHE cation binding domain
MBEFOJME_00469 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
MBEFOJME_00470 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MBEFOJME_00471 7.8e-61 S haloacid dehalogenase-like hydrolase
MBEFOJME_00472 1.8e-31 S haloacid dehalogenase-like hydrolase
MBEFOJME_00473 4.6e-241 metY 2.5.1.49 E o-acetylhomoserine
MBEFOJME_00474 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MBEFOJME_00475 5.3e-240 agcS E (Alanine) symporter
MBEFOJME_00476 1.6e-247 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MBEFOJME_00477 1.4e-104 yfiF3 K sequence-specific DNA binding
MBEFOJME_00478 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
MBEFOJME_00479 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
MBEFOJME_00481 1.8e-67 yecS P ABC transporter (Permease
MBEFOJME_00482 8.8e-134 yckB ET Belongs to the bacterial solute-binding protein 3 family
MBEFOJME_00483 1e-103 nylA 3.5.1.4 J Belongs to the amidase family
MBEFOJME_00484 7.9e-266 dtpT E transporter
MBEFOJME_00485 7.5e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MBEFOJME_00486 9.1e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MBEFOJME_00487 5.6e-146 csm6 S Psort location Cytoplasmic, score
MBEFOJME_00488 2.8e-38 csm6 S Psort location Cytoplasmic, score
MBEFOJME_00489 3.4e-60 csm6 S Psort location Cytoplasmic, score
MBEFOJME_00490 2.9e-204 csm5 L CRISPR-associated RAMP protein, Csm5 family
MBEFOJME_00491 5.2e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
MBEFOJME_00492 1.6e-117 csm3 L RAMP superfamily
MBEFOJME_00493 9.9e-38 csm2 L Csm2 Type III-A
MBEFOJME_00494 0.0 csm1 S CRISPR-associated protein Csm1 family
MBEFOJME_00495 9.9e-132 cas6 S Pfam:DUF2276
MBEFOJME_00496 9.8e-55 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBEFOJME_00497 2.3e-187 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBEFOJME_00498 9.3e-175 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MBEFOJME_00499 1.8e-147 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MBEFOJME_00500 5.9e-97 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
MBEFOJME_00501 1.1e-87 S TraX protein
MBEFOJME_00502 9.2e-311 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MBEFOJME_00503 7.8e-38 tnp L DDE domain
MBEFOJME_00504 8e-23 L Transposase
MBEFOJME_00505 4.7e-140 L Integrase core domain
MBEFOJME_00506 2.1e-92 2.7.8.12 GT2 S Glycosyltransferase like family 2
MBEFOJME_00507 2.5e-17 tnp L DDE domain
MBEFOJME_00508 7.1e-08 tnp L DDE domain
MBEFOJME_00509 7.8e-242 cps1C S Polysaccharide biosynthesis protein
MBEFOJME_00510 7.1e-13 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MBEFOJME_00511 3.6e-157 L Transposase
MBEFOJME_00512 8.8e-46 L Transposase
MBEFOJME_00513 2.9e-94 V VanZ like family
MBEFOJME_00514 1e-86 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MBEFOJME_00515 1.6e-44 G alpha-ribazole phosphatase activity
MBEFOJME_00516 1.3e-199 S hmm pf01594
MBEFOJME_00517 2e-18 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MBEFOJME_00518 7.1e-139 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MBEFOJME_00519 7.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MBEFOJME_00520 4.9e-39 S granule-associated protein
MBEFOJME_00521 5.9e-291 S unusual protein kinase
MBEFOJME_00522 3.4e-29 estA E Lysophospholipase L1 and related esterases
MBEFOJME_00523 2.8e-70 estA E GDSL-like protein
MBEFOJME_00524 1.9e-158 rssA S Phospholipase, patatin family
MBEFOJME_00525 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MBEFOJME_00526 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MBEFOJME_00527 8.2e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MBEFOJME_00528 2.8e-65 S the current gene model (or a revised gene model) may contain a frame shift
MBEFOJME_00529 5e-38 P membrane protein (DUF2207)
MBEFOJME_00530 6e-185 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MBEFOJME_00531 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MBEFOJME_00532 1e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MBEFOJME_00533 0.0 lpdA 1.8.1.4 C Dehydrogenase
MBEFOJME_00534 9.9e-12 3.5.1.28 NU amidase activity
MBEFOJME_00535 2.7e-67 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MBEFOJME_00536 1.9e-186 3.5.1.28 M GBS Bsp-like repeat
MBEFOJME_00537 4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00538 1.5e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00539 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00540 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00541 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00542 2.3e-151 ycdO P periplasmic lipoprotein involved in iron transport
MBEFOJME_00543 5.6e-233 ycdB P peroxidase
MBEFOJME_00544 3.9e-301 ywbL P COG0672 High-affinity Fe2 Pb2 permease
MBEFOJME_00545 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MBEFOJME_00546 4.6e-25 tatA U protein secretion
MBEFOJME_00547 2.3e-23 L Transposase
MBEFOJME_00548 3.4e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
MBEFOJME_00549 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MBEFOJME_00550 3.7e-09
MBEFOJME_00551 1.5e-17
MBEFOJME_00552 8.5e-187 lplA 6.3.1.20 H Lipoate-protein ligase
MBEFOJME_00553 7e-195 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
MBEFOJME_00554 3.5e-32 L Integrase core domain protein
MBEFOJME_00556 2.1e-196 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MBEFOJME_00557 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MBEFOJME_00558 2.3e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MBEFOJME_00559 3.5e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MBEFOJME_00560 1.5e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MBEFOJME_00561 4.4e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MBEFOJME_00562 1.9e-127 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MBEFOJME_00563 8.9e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MBEFOJME_00564 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MBEFOJME_00565 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
MBEFOJME_00566 5.6e-240 rodA D Belongs to the SEDS family
MBEFOJME_00567 1.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MBEFOJME_00568 4.2e-118 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MBEFOJME_00569 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MBEFOJME_00570 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MBEFOJME_00571 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
MBEFOJME_00572 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MBEFOJME_00573 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MBEFOJME_00574 2.9e-125 dnaD
MBEFOJME_00575 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MBEFOJME_00578 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MBEFOJME_00579 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
MBEFOJME_00580 6.6e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MBEFOJME_00581 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MBEFOJME_00582 3.7e-73 argR K Regulates arginine biosynthesis genes
MBEFOJME_00583 1.7e-304 recN L May be involved in recombinational repair of damaged DNA
MBEFOJME_00584 1e-148 DegV S DegV family
MBEFOJME_00585 6e-144 ypmR E lipolytic protein G-D-S-L family
MBEFOJME_00586 1.7e-83 ypmS S Protein conserved in bacteria
MBEFOJME_00587 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MBEFOJME_00589 3.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MBEFOJME_00590 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MBEFOJME_00591 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MBEFOJME_00592 7.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MBEFOJME_00593 2.5e-43 ysdA L Membrane
MBEFOJME_00594 4.4e-274 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MBEFOJME_00595 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MBEFOJME_00596 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
MBEFOJME_00597 0.0 dnaE 2.7.7.7 L DNA polymerase
MBEFOJME_00598 1.2e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MBEFOJME_00599 6.7e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MBEFOJME_00602 2.7e-26 Q the current gene model (or a revised gene model) may contain a frame shift
MBEFOJME_00603 8.1e-42 Q the current gene model (or a revised gene model) may contain a frame shift
MBEFOJME_00605 3.5e-172 yeiH S Membrane
MBEFOJME_00606 1.6e-118 mur1 NU muramidase
MBEFOJME_00607 4.2e-20 L transposase activity
MBEFOJME_00608 4.5e-166 cpsY K Transcriptional regulator
MBEFOJME_00609 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MBEFOJME_00610 1.2e-57 phnA P Alkylphosphonate utilization operon protein PhnA
MBEFOJME_00611 5.3e-105 artQ P ABC transporter (Permease
MBEFOJME_00612 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBEFOJME_00613 1.2e-157 aatB ET ABC transporter substrate-binding protein
MBEFOJME_00614 7.1e-147 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MBEFOJME_00615 1.7e-57 adhP 1.1.1.1 C alcohol dehydrogenase
MBEFOJME_00616 1.3e-106 adhP 1.1.1.1 C alcohol dehydrogenase
MBEFOJME_00617 2.8e-49 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
MBEFOJME_00618 3.9e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MBEFOJME_00619 4.5e-126 gntR1 K transcriptional
MBEFOJME_00620 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MBEFOJME_00621 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MBEFOJME_00622 4.1e-87 niaX
MBEFOJME_00623 8.6e-90 niaR S small molecule binding protein (contains 3H domain)
MBEFOJME_00624 1.8e-127 K DNA-binding helix-turn-helix protein
MBEFOJME_00625 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MBEFOJME_00626 1.4e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MBEFOJME_00627 8.2e-168 GK ROK family
MBEFOJME_00628 8.3e-159 dprA LU DNA protecting protein DprA
MBEFOJME_00629 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MBEFOJME_00630 6.9e-150 S TraX protein
MBEFOJME_00631 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBEFOJME_00632 2.8e-252 T PhoQ Sensor
MBEFOJME_00633 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MBEFOJME_00634 7.2e-152 XK27_05470 E Methionine synthase
MBEFOJME_00635 7.5e-21 XK27_05470 E Methionine synthase
MBEFOJME_00636 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MBEFOJME_00637 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MBEFOJME_00638 2.2e-49 IQ Acetoin reductase
MBEFOJME_00639 3.9e-19 IQ Acetoin reductase
MBEFOJME_00640 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MBEFOJME_00641 6.7e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MBEFOJME_00644 2.5e-30 hmpT S membrane
MBEFOJME_00645 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
MBEFOJME_00646 2.5e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MBEFOJME_00647 4.2e-190 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MBEFOJME_00648 9.8e-298 dnaK O Heat shock 70 kDa protein
MBEFOJME_00649 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MBEFOJME_00650 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MBEFOJME_00651 1.3e-102 acmA 3.2.1.17 NU amidase activity
MBEFOJME_00652 2.1e-143 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MBEFOJME_00653 5.4e-135 ais G Phosphoglycerate mutase
MBEFOJME_00654 8.7e-243 XK27_08635 S UPF0210 protein
MBEFOJME_00655 6.1e-39 gcvR T UPF0237 protein
MBEFOJME_00656 2.5e-225 capA M Bacterial capsule synthesis protein
MBEFOJME_00657 2.9e-125 tnp L Transposase IS66 family
MBEFOJME_00658 1e-30 dhaL 2.7.1.121 G Dihydroxyacetone kinase
MBEFOJME_00659 3.3e-247 G polysaccharide deacetylase
MBEFOJME_00660 2.9e-125 tnp L Transposase IS66 family
MBEFOJME_00661 6.8e-76 isp2 S pathogenesis
MBEFOJME_00663 1.7e-54
MBEFOJME_00664 7e-124 tnp L DDE domain
MBEFOJME_00665 2.3e-27 S Protein of unknown function (DUF2568)
MBEFOJME_00666 1.8e-79 tnpR L Resolvase, N terminal domain
MBEFOJME_00667 7e-124 tnp L DDE domain
MBEFOJME_00668 6.4e-55
MBEFOJME_00670 8.7e-41 S Helix-turn-helix domain
MBEFOJME_00671 4.5e-83 int L Belongs to the 'phage' integrase family
MBEFOJME_00672 8.5e-112 int L Belongs to the 'phage' integrase family
MBEFOJME_00673 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MBEFOJME_00674 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MBEFOJME_00675 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MBEFOJME_00676 1.8e-31 K helix-turn-helix
MBEFOJME_00677 3.4e-155 degV S DegV family
MBEFOJME_00678 3.5e-91 yacP S RNA-binding protein containing a PIN domain
MBEFOJME_00679 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MBEFOJME_00682 4.2e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MBEFOJME_00683 1.7e-259 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MBEFOJME_00684 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
MBEFOJME_00685 6.9e-144 S SseB protein N-terminal domain
MBEFOJME_00686 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MBEFOJME_00687 2.1e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MBEFOJME_00688 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MBEFOJME_00689 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBEFOJME_00690 3.5e-52 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBEFOJME_00691 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
MBEFOJME_00693 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
MBEFOJME_00695 6.6e-30 ycaO O OsmC-like protein
MBEFOJME_00696 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
MBEFOJME_00699 7.3e-135 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MBEFOJME_00701 1.4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MBEFOJME_00702 2.4e-16 XK27_00735
MBEFOJME_00703 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBEFOJME_00704 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
MBEFOJME_00705 2.4e-33 S CAAX amino terminal protease family protein
MBEFOJME_00706 4.3e-82 S CAAX amino terminal protease family protein
MBEFOJME_00708 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MBEFOJME_00709 2.3e-81 mutT 3.6.1.55 F Nudix family
MBEFOJME_00710 2.8e-143 ET Belongs to the bacterial solute-binding protein 3 family
MBEFOJME_00711 1.6e-135 ET ABC transporter
MBEFOJME_00712 2.1e-202 arcT 2.6.1.1 E Aminotransferase
MBEFOJME_00713 2.7e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
MBEFOJME_00714 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MBEFOJME_00715 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MBEFOJME_00716 1.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MBEFOJME_00717 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
MBEFOJME_00718 9.5e-172 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
MBEFOJME_00719 2.9e-246
MBEFOJME_00720 4.5e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MBEFOJME_00721 2.2e-125 ycbB S Glycosyl transferase family 2
MBEFOJME_00722 5.3e-48 XK27_09090 S Uncharacterized conserved protein (DUF2304)
MBEFOJME_00723 9.8e-220 amrA S polysaccharide biosynthetic process
MBEFOJME_00724 5.6e-186 tagF 2.7.8.12 M Glycosyl transferase, family 2
MBEFOJME_00725 4.6e-139 S Predicted membrane protein (DUF2142)
MBEFOJME_00726 4.4e-227 rgpA GT4 M Domain of unknown function (DUF1972)
MBEFOJME_00727 6.3e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
MBEFOJME_00728 1.4e-142 rgpC GM Transport permease protein
MBEFOJME_00729 8.7e-226 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MBEFOJME_00730 3.1e-195 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MBEFOJME_00731 0.0 rgpF M Rhamnan synthesis protein F
MBEFOJME_00732 6.2e-120 radC E Belongs to the UPF0758 family
MBEFOJME_00733 3.9e-130 puuD T peptidase C26
MBEFOJME_00734 3.6e-117 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MBEFOJME_00735 2e-58 XK27_04120 S Putative amino acid metabolism
MBEFOJME_00736 7e-206 iscS 2.8.1.7 E Cysteine desulfurase
MBEFOJME_00737 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MBEFOJME_00738 1.5e-103 yjbK S Adenylate cyclase
MBEFOJME_00739 5.5e-121 yjbM 2.7.6.5 S Gtp pyrophosphokinase
MBEFOJME_00740 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MBEFOJME_00741 1.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MBEFOJME_00742 5.9e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MBEFOJME_00743 8.9e-18 L transposase activity
MBEFOJME_00744 1.1e-23 L transposase activity
MBEFOJME_00745 1e-110 L Integrase core domain protein
MBEFOJME_00746 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
MBEFOJME_00747 1.4e-40 tatD L Hydrolase, tatd
MBEFOJME_00748 6.5e-45 oppF P Belongs to the ABC transporter superfamily
MBEFOJME_00749 1.2e-24 oppF P Belongs to the ABC transporter superfamily
MBEFOJME_00750 4.1e-158 L COG2801 Transposase and inactivated derivatives
MBEFOJME_00751 8.1e-45 L Transposase
MBEFOJME_00752 0.0 amiA E ABC transporter, substrate-binding protein, family 5
MBEFOJME_00753 1.1e-270 amiC P ABC transporter (Permease
MBEFOJME_00754 2.4e-167 amiD P ABC transporter (Permease
MBEFOJME_00755 7.9e-202 oppD P Belongs to the ABC transporter superfamily
MBEFOJME_00756 7.3e-172 oppF P Belongs to the ABC transporter superfamily
MBEFOJME_00757 5.6e-133 V ATPase activity
MBEFOJME_00758 9.8e-121 skfE V abc transporter atp-binding protein
MBEFOJME_00759 8.6e-63 yvoA_1 K Transcriptional
MBEFOJME_00760 2.1e-148 supH S overlaps another CDS with the same product name
MBEFOJME_00761 5.3e-150 XK27_02985 S overlaps another CDS with the same product name
MBEFOJME_00762 2e-213 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MBEFOJME_00763 9.8e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MBEFOJME_00764 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
MBEFOJME_00765 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MBEFOJME_00766 2.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MBEFOJME_00767 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MBEFOJME_00768 2e-132 stp 3.1.3.16 T phosphatase
MBEFOJME_00769 1.6e-306 prkC 2.7.11.1 KLT serine threonine protein kinase
MBEFOJME_00770 9.1e-119 yvqF KT membrane
MBEFOJME_00771 5.8e-175 vraS 2.7.13.3 T Histidine kinase
MBEFOJME_00772 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MBEFOJME_00775 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MBEFOJME_00776 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MBEFOJME_00777 1.6e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MBEFOJME_00778 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MBEFOJME_00779 1.7e-120 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00780 1.8e-33 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00781 6.5e-75 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00782 4.6e-58 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
MBEFOJME_00783 6.4e-62 L Transposase
MBEFOJME_00784 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
MBEFOJME_00785 2.8e-39 V (ABC) transporter
MBEFOJME_00786 9.6e-56 V abc transporter atp-binding protein
MBEFOJME_00787 5.2e-38 V abc transporter atp-binding protein
MBEFOJME_00788 1.4e-179 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
MBEFOJME_00789 3.3e-74 M translation initiation factor activity
MBEFOJME_00790 1.2e-25 L transposition
MBEFOJME_00791 2.7e-08 L Integrase core domain protein
MBEFOJME_00792 2.3e-184 galR K Transcriptional regulator
MBEFOJME_00793 1.6e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MBEFOJME_00794 2.1e-293 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
MBEFOJME_00795 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MBEFOJME_00796 2.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MBEFOJME_00797 0.0 lacS G transporter
MBEFOJME_00798 0.0 lacL 3.2.1.23 G -beta-galactosidase
MBEFOJME_00799 2e-230 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MBEFOJME_00800 0.0 sbcC L ATPase involved in DNA repair
MBEFOJME_00801 3.5e-52
MBEFOJME_00803 1.8e-87 L transposase activity
MBEFOJME_00804 1.4e-150 L Integrase core domain protein
MBEFOJME_00805 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MBEFOJME_00807 5.5e-258 I radical SAM domain protein
MBEFOJME_00808 1.2e-176 EGP Major Facilitator Superfamily
MBEFOJME_00809 3.9e-110 C Fe-S oxidoreductases
MBEFOJME_00811 1.5e-150 V MatE
MBEFOJME_00812 8e-37 L transposase activity
MBEFOJME_00813 7.4e-21 XK27_08085
MBEFOJME_00814 5.6e-92 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MBEFOJME_00815 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
MBEFOJME_00816 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MBEFOJME_00817 1.1e-121 ylfI S tigr01906
MBEFOJME_00818 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MBEFOJME_00819 5.7e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
MBEFOJME_00820 1.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
MBEFOJME_00823 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MBEFOJME_00824 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MBEFOJME_00825 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MBEFOJME_00826 1.6e-207 yurR 1.4.5.1 E oxidoreductase
MBEFOJME_00827 6.4e-29 zupT P transporter
MBEFOJME_00828 2.3e-14 zupT P Mediates zinc uptake. May also transport other divalent cations
MBEFOJME_00829 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MBEFOJME_00830 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
MBEFOJME_00831 1.7e-70 gtrA S GtrA-like protein
MBEFOJME_00832 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MBEFOJME_00833 6e-169 ybbR S Protein conserved in bacteria
MBEFOJME_00834 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MBEFOJME_00835 2.2e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
MBEFOJME_00836 8.7e-150 cobQ S glutamine amidotransferase
MBEFOJME_00837 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MBEFOJME_00838 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
MBEFOJME_00839 0.0 uup S abc transporter atp-binding protein
MBEFOJME_00840 6.2e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MBEFOJME_00841 3.5e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
MBEFOJME_00842 2.1e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MBEFOJME_00843 3.3e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
MBEFOJME_00844 1.9e-197 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
MBEFOJME_00845 3.1e-172 yxaM EGP Major facilitator Superfamily
MBEFOJME_00846 1.4e-41 adk 2.7.4.3 F topology modulation protein
MBEFOJME_00847 5.4e-197 L transposase, IS4 family
MBEFOJME_00848 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MBEFOJME_00849 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MBEFOJME_00850 1.7e-35 XK27_09805 S MORN repeat protein
MBEFOJME_00851 0.0 XK27_09800 I Acyltransferase
MBEFOJME_00852 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MBEFOJME_00853 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
MBEFOJME_00854 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MBEFOJME_00855 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
MBEFOJME_00856 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MBEFOJME_00857 8.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MBEFOJME_00858 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MBEFOJME_00859 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MBEFOJME_00860 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MBEFOJME_00861 7.2e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MBEFOJME_00862 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
MBEFOJME_00863 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MBEFOJME_00864 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MBEFOJME_00865 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MBEFOJME_00866 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MBEFOJME_00867 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MBEFOJME_00868 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MBEFOJME_00869 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MBEFOJME_00870 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MBEFOJME_00871 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MBEFOJME_00872 2.5e-23 rpmD J ribosomal protein l30
MBEFOJME_00873 4.4e-58 rplO J binds to the 23S rRNA
MBEFOJME_00874 9.6e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MBEFOJME_00875 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MBEFOJME_00876 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MBEFOJME_00877 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MBEFOJME_00878 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MBEFOJME_00879 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MBEFOJME_00880 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MBEFOJME_00881 3.3e-62 rplQ J ribosomal protein l17
MBEFOJME_00882 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MBEFOJME_00885 2.4e-75 XK27_03180 T universal stress protein
MBEFOJME_00886 3.7e-240 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
MBEFOJME_00887 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MBEFOJME_00888 6.8e-101 pncA Q isochorismatase
MBEFOJME_00889 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
MBEFOJME_00890 4.7e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MBEFOJME_00891 5e-98 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MBEFOJME_00892 8.3e-151 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MBEFOJME_00893 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MBEFOJME_00894 1e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MBEFOJME_00895 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MBEFOJME_00896 1.2e-58
MBEFOJME_00897 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MBEFOJME_00898 1.8e-98 yqeG S hydrolase of the HAD superfamily
MBEFOJME_00899 1.7e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MBEFOJME_00900 3.5e-49 yhbY J RNA-binding protein
MBEFOJME_00901 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MBEFOJME_00902 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MBEFOJME_00903 6e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MBEFOJME_00904 2e-140 yqeM Q Methyltransferase domain protein
MBEFOJME_00905 6.9e-206 ylbM S Belongs to the UPF0348 family
MBEFOJME_00906 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
MBEFOJME_00907 5.1e-259 pepC 3.4.22.40 E aminopeptidase
MBEFOJME_00908 3.2e-77 yhaI L Membrane
MBEFOJME_00909 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MBEFOJME_00910 1.3e-276 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MBEFOJME_00911 1e-139 S COG1073 Hydrolases of the alpha beta superfamily
MBEFOJME_00912 2.6e-76 S thiolester hydrolase activity
MBEFOJME_00914 3.8e-40 K transcriptional
MBEFOJME_00915 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MBEFOJME_00916 1.6e-137 glcR K transcriptional regulator (DeoR family)
MBEFOJME_00917 6.2e-35 cof Q phosphatase activity
MBEFOJME_00918 6e-55 cof Q phosphatase activity
MBEFOJME_00919 4.6e-85 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
MBEFOJME_00920 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
MBEFOJME_00921 5.7e-25 secE U Belongs to the SecE SEC61-gamma family
MBEFOJME_00922 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MBEFOJME_00923 1.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MBEFOJME_00924 6.8e-56 S TM2 domain
MBEFOJME_00925 6.1e-43
MBEFOJME_00928 6.4e-18 L transposase activity
MBEFOJME_00929 4.4e-37 L Transposase
MBEFOJME_00930 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MBEFOJME_00931 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MBEFOJME_00932 5.2e-142 cmpC S abc transporter atp-binding protein
MBEFOJME_00933 0.0 WQ51_06230 S ABC transporter substrate binding protein
MBEFOJME_00935 2.7e-95 S Hydrophobic domain protein
MBEFOJME_00936 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
MBEFOJME_00939 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MBEFOJME_00940 1e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MBEFOJME_00941 1.4e-14 metE 2.1.1.14 E Methionine synthase
MBEFOJME_00942 5.2e-55 metE 2.1.1.14 E Methionine synthase
MBEFOJME_00943 1.4e-53 metE 2.1.1.14 E Methionine synthase
MBEFOJME_00944 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
MBEFOJME_00946 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MBEFOJME_00947 9.3e-167 XK27_01785 S cog cog1284
MBEFOJME_00948 1.8e-147 yaaA S Belongs to the UPF0246 family
MBEFOJME_00949 3.7e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MBEFOJME_00950 3.4e-91 XK27_10930 K acetyltransferase
MBEFOJME_00951 7.5e-14
MBEFOJME_00952 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MBEFOJME_00953 2.6e-297 ccs S the current gene model (or a revised gene model) may contain a frame shift
MBEFOJME_00954 4.2e-44 yrzB S Belongs to the UPF0473 family
MBEFOJME_00955 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MBEFOJME_00956 2.8e-44 yrzL S Belongs to the UPF0297 family
MBEFOJME_00957 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MBEFOJME_00958 5.2e-237 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
MBEFOJME_00960 2.2e-132 int L Belongs to the 'phage' integrase family
MBEFOJME_00961 2.5e-89 K sequence-specific DNA binding
MBEFOJME_00962 3.9e-287 V ABC transporter transmembrane region
MBEFOJME_00963 3.4e-191 C Radical SAM
MBEFOJME_00964 1.8e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MBEFOJME_00965 7.4e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MBEFOJME_00966 2.2e-27 XK27_08585 S Psort location CytoplasmicMembrane, score
MBEFOJME_00967 1.2e-23 XK27_08585 S Psort location CytoplasmicMembrane, score
MBEFOJME_00968 8.5e-33 fnt P Formate nitrite transporter
MBEFOJME_00969 7.9e-72 fnt P Formate nitrite transporter
MBEFOJME_00970 2.5e-135 XK27_09615 C reductase
MBEFOJME_00971 8.3e-75 XK27_09615 C reductase
MBEFOJME_00972 2.8e-76 XK27_09620 S reductase
MBEFOJME_00973 4.7e-20 XK27_09620 S FMN reductase (NADPH) activity
MBEFOJME_00974 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MBEFOJME_00975 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MBEFOJME_00976 6.2e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
MBEFOJME_00977 7.3e-59 WQ51_05710 S Mitochondrial biogenesis AIM24
MBEFOJME_00978 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MBEFOJME_00979 9.2e-51 S Protein of unknown function (DUF3397)
MBEFOJME_00980 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MBEFOJME_00981 4.8e-120 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MBEFOJME_00982 1.6e-68 amiA E transmembrane transport
MBEFOJME_00983 1.4e-81 amiA E transmembrane transport
MBEFOJME_00984 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MBEFOJME_00985 2e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MBEFOJME_00986 4.1e-264 argH 4.3.2.1 E Argininosuccinate lyase
MBEFOJME_00987 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MBEFOJME_00988 1.7e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MBEFOJME_00989 1.4e-184 jag S RNA-binding protein
MBEFOJME_00990 1e-13 rpmH J Ribosomal protein L34
MBEFOJME_00991 1e-33 L Transposase
MBEFOJME_00992 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MBEFOJME_00993 2.3e-161 S CHAP domain
MBEFOJME_00994 3.4e-241 purD 6.3.4.13 F Belongs to the GARS family
MBEFOJME_00995 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MBEFOJME_00996 3.8e-204 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MBEFOJME_00997 3.2e-46 1.1.1.169 H Ketopantoate reductase
MBEFOJME_00998 5.6e-86 1.1.1.169 H Ketopantoate reductase
MBEFOJME_00999 6.6e-34
MBEFOJME_01000 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MBEFOJME_01001 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MBEFOJME_01002 8.2e-70 argR K Regulates arginine biosynthesis genes
MBEFOJME_01003 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MBEFOJME_01004 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MBEFOJME_01005 1.1e-77 S Protein of unknown function (DUF3021)
MBEFOJME_01006 5.4e-69 K LytTr DNA-binding domain
MBEFOJME_01008 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MBEFOJME_01010 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MBEFOJME_01011 2.4e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
MBEFOJME_01012 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
MBEFOJME_01013 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MBEFOJME_01014 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
MBEFOJME_01015 2.8e-93 pat 2.3.1.183 M acetyltransferase
MBEFOJME_01016 7.3e-82 alkD L Dna alkylation repair
MBEFOJME_01017 7.3e-200 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MBEFOJME_01018 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MBEFOJME_01019 8.4e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MBEFOJME_01020 0.0 smc D Required for chromosome condensation and partitioning
MBEFOJME_01021 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MBEFOJME_01022 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MBEFOJME_01023 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MBEFOJME_01025 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
MBEFOJME_01026 7.7e-241 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MBEFOJME_01028 2e-86 S ECF-type riboflavin transporter, S component
MBEFOJME_01029 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MBEFOJME_01030 8.7e-85 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
MBEFOJME_01031 3.3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
MBEFOJME_01032 1.9e-294 yfmM S abc transporter atp-binding protein
MBEFOJME_01033 3.4e-258 noxE P NADH oxidase
MBEFOJME_01034 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MBEFOJME_01035 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MBEFOJME_01036 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
MBEFOJME_01037 3.9e-53 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
MBEFOJME_01038 1.8e-165 ypuA S secreted protein
MBEFOJME_01039 3.6e-61 L Transposase (IS116 IS110 IS902 family)
MBEFOJME_01040 1.9e-71 L Transposase (IS116 IS110 IS902 family)
MBEFOJME_01042 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MBEFOJME_01043 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MBEFOJME_01044 8.5e-34 nrdH O Glutaredoxin
MBEFOJME_01045 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MBEFOJME_01046 5.1e-212 citZ 2.3.3.1 C Belongs to the citrate synthase family
MBEFOJME_01047 2e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
MBEFOJME_01048 7.9e-39 ptsH G phosphocarrier protein Hpr
MBEFOJME_01049 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MBEFOJME_01050 1.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MBEFOJME_01051 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MBEFOJME_01052 4.8e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MBEFOJME_01053 1.3e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MBEFOJME_01054 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MBEFOJME_01055 3.4e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MBEFOJME_01056 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MBEFOJME_01057 1.3e-179 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MBEFOJME_01058 7e-144 recO L Involved in DNA repair and RecF pathway recombination
MBEFOJME_01059 2.9e-218 araT 2.6.1.1 E Aminotransferase
MBEFOJME_01060 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MBEFOJME_01061 5.5e-94 usp 3.5.1.28 CBM50 S CHAP domain
MBEFOJME_01062 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MBEFOJME_01063 5.5e-139 mreC M Involved in formation and maintenance of cell shape
MBEFOJME_01065 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MBEFOJME_01066 1.7e-122 comFC S Competence protein
MBEFOJME_01067 4.5e-252 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MBEFOJME_01068 1.1e-110 yvyE 3.4.13.9 S YigZ family
MBEFOJME_01069 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MBEFOJME_01070 3.3e-43 acuB S IMP dehydrogenase activity
MBEFOJME_01071 9.5e-71 acuB S IMP dehydrogenase activity
MBEFOJME_01072 4.8e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
MBEFOJME_01073 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
MBEFOJME_01074 1.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
MBEFOJME_01075 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
MBEFOJME_01076 9.1e-212 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
MBEFOJME_01077 4.6e-45 ylbG S UPF0298 protein
MBEFOJME_01078 1.3e-73 ylbF S Belongs to the UPF0342 family
MBEFOJME_01079 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MBEFOJME_01080 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MBEFOJME_01081 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
MBEFOJME_01083 6.6e-223 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MBEFOJME_01084 6.1e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
MBEFOJME_01085 3.3e-96 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
MBEFOJME_01086 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
MBEFOJME_01087 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MBEFOJME_01088 2.6e-225 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
MBEFOJME_01090 7.6e-74 yvdD 3.2.2.10 S Belongs to the LOG family
MBEFOJME_01091 6.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MBEFOJME_01092 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MBEFOJME_01093 1.4e-41 ylxQ J ribosomal protein
MBEFOJME_01094 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
MBEFOJME_01095 3.1e-212 nusA K Participates in both transcription termination and antitermination
MBEFOJME_01096 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
MBEFOJME_01097 2.5e-220 brpA K Transcriptional
MBEFOJME_01098 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
MBEFOJME_01099 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
MBEFOJME_01100 2.1e-247 pbuO S permease
MBEFOJME_01101 5.6e-152 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MBEFOJME_01102 9.8e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
MBEFOJME_01103 1.3e-174 manL 2.7.1.191 G pts system
MBEFOJME_01104 2.3e-116 manM G pts system
MBEFOJME_01105 6.2e-168 manN G PTS system mannose fructose sorbose family IID component
MBEFOJME_01106 4.2e-62 manO S protein conserved in bacteria
MBEFOJME_01107 8.6e-232 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MBEFOJME_01108 7.8e-28 L transposase activity
MBEFOJME_01109 5.7e-23 L Transposase
MBEFOJME_01110 6.7e-49 L transposition
MBEFOJME_01111 3e-27 L Integrase core domain protein
MBEFOJME_01112 6.7e-14 yrdC 3.5.1.19 Q isochorismatase
MBEFOJME_01113 1.2e-34
MBEFOJME_01115 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MBEFOJME_01116 5.2e-167 dnaI L Primosomal protein DnaI
MBEFOJME_01117 6.5e-218 dnaB L Replication initiation and membrane attachment
MBEFOJME_01118 4.7e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MBEFOJME_01119 2.8e-282 T PhoQ Sensor
MBEFOJME_01120 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBEFOJME_01121 2.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
MBEFOJME_01122 1.1e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
MBEFOJME_01123 5.2e-243 P COG0168 Trk-type K transport systems, membrane components
MBEFOJME_01124 5.5e-121 ktrA P COG0569 K transport systems, NAD-binding component
MBEFOJME_01125 9.7e-13 ulaG S L-ascorbate 6-phosphate lactonase
MBEFOJME_01126 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MBEFOJME_01127 1.2e-146 cbiQ P cobalt transport
MBEFOJME_01128 0.0 ykoD P abc transporter atp-binding protein
MBEFOJME_01129 9.4e-95 S UPF0397 protein
MBEFOJME_01130 3.2e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
MBEFOJME_01131 4.6e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MBEFOJME_01132 3e-98 metI P ABC transporter (Permease
MBEFOJME_01133 1.2e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MBEFOJME_01134 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
MBEFOJME_01135 1.2e-61 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
MBEFOJME_01136 1.1e-86 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
MBEFOJME_01137 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
MBEFOJME_01138 4e-153 ET amino acid transport
MBEFOJME_01139 3.8e-205 EGP Transmembrane secretion effector
MBEFOJME_01140 0.0 3.3.1.1, 3.6.1.55, 3.6.1.67 F NUDIX domain
MBEFOJME_01141 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MBEFOJME_01142 2.3e-116 ET amino acid transport
MBEFOJME_01143 1.6e-22 ET amino acid transport
MBEFOJME_01144 3.1e-130 cbiO P ABC transporter
MBEFOJME_01145 6e-135 P cobalt transport protein
MBEFOJME_01146 2.7e-177 cbiM P PDGLE domain
MBEFOJME_01147 1.3e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MBEFOJME_01148 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MBEFOJME_01149 1.5e-129 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MBEFOJME_01150 6.6e-78 ureE O enzyme active site formation
MBEFOJME_01151 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MBEFOJME_01152 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MBEFOJME_01153 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MBEFOJME_01154 6.8e-95 ureI S AmiS/UreI family transporter
MBEFOJME_01155 9.4e-54 S Domain of unknown function (DUF4173)
MBEFOJME_01156 3.7e-22 yhaI L Membrane
MBEFOJME_01157 6.4e-67 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MBEFOJME_01158 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MBEFOJME_01159 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MBEFOJME_01160 1.9e-33 V protein secretion by the type I secretion system
MBEFOJME_01161 3.3e-161 K sequence-specific DNA binding
MBEFOJME_01162 2.4e-113 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
MBEFOJME_01163 3.9e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MBEFOJME_01164 7.9e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MBEFOJME_01165 1.5e-247 trkA P Potassium transporter peripheral membrane component
MBEFOJME_01166 1.2e-258 trkH P Cation transport protein
MBEFOJME_01167 1.2e-39 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MBEFOJME_01168 6.1e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MBEFOJME_01169 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MBEFOJME_01170 3.8e-120 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MBEFOJME_01171 4.5e-135 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
MBEFOJME_01172 7.8e-85 ykuL S CBS domain
MBEFOJME_01173 3.5e-99 XK27_09740 S Phosphoesterase
MBEFOJME_01174 6.6e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MBEFOJME_01175 1.9e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MBEFOJME_01176 7.6e-36 yneF S UPF0154 protein
MBEFOJME_01177 1e-88 K transcriptional regulator
MBEFOJME_01178 1.6e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MBEFOJME_01181 1.5e-97 ybhL S Belongs to the BI1 family
MBEFOJME_01182 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
MBEFOJME_01183 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MBEFOJME_01184 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MBEFOJME_01185 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MBEFOJME_01186 5.2e-59 L Integrase core domain protein
MBEFOJME_01187 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MBEFOJME_01188 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MBEFOJME_01189 3.5e-82 XK27_09675 K -acetyltransferase
MBEFOJME_01190 9.8e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MBEFOJME_01191 2.5e-23
MBEFOJME_01192 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
MBEFOJME_01193 1.2e-295 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
MBEFOJME_01194 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MBEFOJME_01195 5.1e-51 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MBEFOJME_01196 4.9e-93 ypsA S Belongs to the UPF0398 family
MBEFOJME_01197 2.4e-107 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MBEFOJME_01198 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MBEFOJME_01199 8.6e-15 dinF V Mate efflux family protein
MBEFOJME_01200 3.3e-19 yclQ P ABC-type enterochelin transport system, periplasmic component
MBEFOJME_01201 9.4e-15 yclQ P ABC-type enterochelin transport system, periplasmic component
MBEFOJME_01202 9.2e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
MBEFOJME_01203 1.2e-143 2.4.2.3 F Phosphorylase superfamily
MBEFOJME_01206 4.5e-79 S Alpha/beta hydrolase of unknown function (DUF915)
MBEFOJME_01207 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
MBEFOJME_01208 6e-08 S Hydrolases of the alpha beta superfamily
MBEFOJME_01209 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
MBEFOJME_01210 2.7e-210 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MBEFOJME_01211 1.8e-159 czcD P cation diffusion facilitator family transporter
MBEFOJME_01212 9e-98 K Transcriptional regulator, TetR family
MBEFOJME_01213 1.6e-10
MBEFOJME_01214 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MBEFOJME_01215 6.4e-104 V ABC transporter (Permease
MBEFOJME_01216 3.9e-159 L Transposase
MBEFOJME_01217 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MBEFOJME_01218 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MBEFOJME_01219 6.6e-61 EGP Major facilitator Superfamily
MBEFOJME_01220 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
MBEFOJME_01221 3.6e-88 T PhoQ Sensor
MBEFOJME_01222 2.2e-43 T PhoQ Sensor
MBEFOJME_01223 7.9e-37 T PhoQ Sensor
MBEFOJME_01224 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBEFOJME_01225 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MBEFOJME_01226 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
MBEFOJME_01227 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MBEFOJME_01228 1.7e-94 panT S ECF transporter, substrate-specific component
MBEFOJME_01229 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MBEFOJME_01230 7.3e-166 metF 1.5.1.20 E reductase
MBEFOJME_01231 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MBEFOJME_01233 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
MBEFOJME_01234 0.0 3.6.3.8 P cation transport ATPase
MBEFOJME_01235 2.1e-30 rpsT J rRNA binding
MBEFOJME_01236 5.5e-172 coaA 2.7.1.33 F Pantothenic acid kinase
MBEFOJME_01237 5.7e-106 rsmC 2.1.1.172 J Methyltransferase small domain protein
MBEFOJME_01238 1.2e-57 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MBEFOJME_01239 1.3e-97 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
MBEFOJME_01240 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MBEFOJME_01241 1.3e-39 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MBEFOJME_01242 1.6e-191 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MBEFOJME_01243 3.7e-282 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MBEFOJME_01244 4.7e-191 yufP S Belongs to the binding-protein-dependent transport system permease family
MBEFOJME_01245 6.3e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
MBEFOJME_01246 8.9e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MBEFOJME_01247 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MBEFOJME_01248 3.1e-81 ypmB S Protein conserved in bacteria
MBEFOJME_01249 1.6e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MBEFOJME_01250 4.2e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
MBEFOJME_01251 1.5e-07
MBEFOJME_01252 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
MBEFOJME_01253 2e-09 L thioesterase
MBEFOJME_01254 6.6e-142 S Macro domain protein
MBEFOJME_01255 4.8e-51 trxA O Belongs to the thioredoxin family
MBEFOJME_01256 7.2e-74 yccU S CoA-binding protein
MBEFOJME_01257 1.6e-143 tatD L Hydrolase, tatd
MBEFOJME_01258 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MBEFOJME_01259 8.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MBEFOJME_01261 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MBEFOJME_01262 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MBEFOJME_01263 3.1e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
MBEFOJME_01264 6.9e-173 rmuC S RmuC domain protein
MBEFOJME_01265 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
MBEFOJME_01266 1.1e-142 purR 2.4.2.7 F operon repressor
MBEFOJME_01267 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MBEFOJME_01268 6.7e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MBEFOJME_01269 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MBEFOJME_01270 2.1e-205 GT4 M Glycosyltransferase, group 1 family protein
MBEFOJME_01271 2.4e-102 S Polysaccharide biosynthesis C-terminal domain
MBEFOJME_01272 4.7e-15 S Polysaccharide pyruvyl transferase
MBEFOJME_01273 2.6e-08 pssE S Glycosyltransferase family 28 C-terminal domain
MBEFOJME_01274 3.7e-40 pssE S Glycosyltransferase family 28 C-terminal domain
MBEFOJME_01275 9.8e-82 cpsF M Oligosaccharide biosynthesis protein Alg14 like
MBEFOJME_01276 2.6e-180 cpsE M Bacterial sugar transferase
MBEFOJME_01278 5.5e-112 XK27_06780 V FtsX-like permease family
MBEFOJME_01279 5.2e-45 XK27_06780 V FtsX-like permease family
MBEFOJME_01280 3.8e-55 XK27_06780 V FtsX-like permease family
MBEFOJME_01281 1.2e-24 XK27_06780 V FtsX-like permease family
MBEFOJME_01282 2.1e-219 L Transposase
MBEFOJME_01283 1.7e-08
MBEFOJME_01284 4.7e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
MBEFOJME_01285 1.6e-77 XK27_10720 D peptidase activity
MBEFOJME_01286 5.9e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
MBEFOJME_01287 1.8e-08 4.2.1.53 S Myosin-crossreactive antigen
MBEFOJME_01288 4.2e-20
MBEFOJME_01289 1.5e-40 M Glycosyltransferase like family 2
MBEFOJME_01290 9.5e-15 M O-antigen ligase
MBEFOJME_01291 7.6e-73 MA20_17390 GT4 M Glycosyl transferases group 1
MBEFOJME_01292 7.7e-56 M Glycosyl transferases group 1
MBEFOJME_01293 4.3e-11 waaB GT4 M Glycosyl transferases group 1
MBEFOJME_01295 7.7e-46 pssE S Glycosyltransferase family 28 C-terminal domain
MBEFOJME_01296 3.2e-64 cpsF M Oligosaccharide biosynthesis protein Alg14 like
MBEFOJME_01297 1.6e-23 rgpAc GT4 M group 1 family protein
MBEFOJME_01298 2.6e-250 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MBEFOJME_01299 2.9e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
MBEFOJME_01300 5e-101 cps4C M biosynthesis protein
MBEFOJME_01301 3.9e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
MBEFOJME_01302 8.3e-255 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
MBEFOJME_01303 8e-42 K Cold-Shock Protein
MBEFOJME_01304 5.4e-32 cspD K Cold shock protein domain
MBEFOJME_01305 8.4e-168 pepD E Dipeptidase
MBEFOJME_01306 8.7e-162 whiA K May be required for sporulation
MBEFOJME_01307 3.6e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MBEFOJME_01308 1.2e-163 rapZ S Displays ATPase and GTPase activities
MBEFOJME_01309 2.8e-137 yejC S cyclic nucleotide-binding protein
MBEFOJME_01310 2.2e-19 D nuclear chromosome segregation
MBEFOJME_01311 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
MBEFOJME_01312 3.9e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MBEFOJME_01313 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MBEFOJME_01314 2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MBEFOJME_01315 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
MBEFOJME_01317 7.9e-76 yocD 3.4.17.13 V carboxypeptidase activity
MBEFOJME_01318 4.6e-91 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MBEFOJME_01320 1.3e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
MBEFOJME_01321 1.9e-181 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MBEFOJME_01322 1.1e-83 S Putative small multi-drug export protein
MBEFOJME_01323 6.2e-76 ctsR K Belongs to the CtsR family
MBEFOJME_01324 0.0 clpC O Belongs to the ClpA ClpB family
MBEFOJME_01325 3.2e-151 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MBEFOJME_01326 1.8e-32 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MBEFOJME_01327 1.7e-28 potC P Binding-protein-dependent transport system inner membrane component
MBEFOJME_01328 8.9e-206 potD P spermidine putrescine ABC transporter
MBEFOJME_01329 3.1e-268 clcA P Chloride transporter, ClC family
MBEFOJME_01330 0.0 prtS 3.4.21.96 O Belongs to the peptidase S8 family
MBEFOJME_01331 1.9e-21 L Helix-turn-helix domain
MBEFOJME_01332 2.5e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
MBEFOJME_01333 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
MBEFOJME_01334 7.4e-109 6.3.2.2 H ergothioneine biosynthetic process
MBEFOJME_01336 9e-164 fba 4.1.2.13, 4.1.2.29 G aldolase
MBEFOJME_01337 2.2e-282 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
MBEFOJME_01339 5.7e-217 S MvaI/BcnI restriction endonuclease family
MBEFOJME_01341 7.7e-13
MBEFOJME_01342 1.3e-31 S Hypothetical protein (DUF2513)
MBEFOJME_01343 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
MBEFOJME_01344 1.9e-115 S Haloacid dehalogenase-like hydrolase
MBEFOJME_01345 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
MBEFOJME_01346 4e-72 marR K Transcriptional regulator, MarR family
MBEFOJME_01347 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MBEFOJME_01348 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MBEFOJME_01349 5.8e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
MBEFOJME_01350 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MBEFOJME_01351 1.6e-126 IQ reductase
MBEFOJME_01352 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MBEFOJME_01353 7.7e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MBEFOJME_01354 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MBEFOJME_01355 1.7e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MBEFOJME_01356 1.6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MBEFOJME_01357 3e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MBEFOJME_01358 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MBEFOJME_01359 9.9e-91 tnp L Transposase
MBEFOJME_01360 1.4e-60 S Bacterial PH domain
MBEFOJME_01364 1.5e-27 S Antidote-toxin recognition MazE, bacterial antitoxin
MBEFOJME_01365 7.4e-155 L COG2801 Transposase and inactivated derivatives
MBEFOJME_01366 6.6e-38 L transposase activity
MBEFOJME_01367 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
MBEFOJME_01368 1.8e-84 L Transposase
MBEFOJME_01369 5.6e-114 fruR K transcriptional
MBEFOJME_01370 5.5e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MBEFOJME_01371 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
MBEFOJME_01372 2.2e-49 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
MBEFOJME_01373 2.7e-126 fruA 2.7.1.202 G phosphotransferase system
MBEFOJME_01374 5.3e-35 fruA 2.7.1.202 G phosphotransferase system
MBEFOJME_01375 1.4e-261 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MBEFOJME_01376 3.1e-242 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MBEFOJME_01378 6.1e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
MBEFOJME_01379 8e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MBEFOJME_01380 5.5e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MBEFOJME_01381 8e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MBEFOJME_01382 6.4e-29 2.3.1.128 K acetyltransferase
MBEFOJME_01383 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MBEFOJME_01384 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MBEFOJME_01385 1.7e-133 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MBEFOJME_01386 2.6e-64 WQ51_03320 S cog cog4835
MBEFOJME_01387 9.8e-91 XK27_08360 S EDD domain protein, DegV family
MBEFOJME_01388 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MBEFOJME_01389 2.6e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MBEFOJME_01390 0.0 yfmR S abc transporter atp-binding protein
MBEFOJME_01391 1.6e-24 U response to pH
MBEFOJME_01392 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
MBEFOJME_01393 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
MBEFOJME_01394 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MBEFOJME_01395 1e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MBEFOJME_01396 1.9e-77 K DNA-binding transcription factor activity
MBEFOJME_01397 0.0 lmrA1 V abc transporter atp-binding protein
MBEFOJME_01398 0.0 lmrA2 V abc transporter atp-binding protein
MBEFOJME_01399 5.4e-45 K Acetyltransferase (GNAT) family
MBEFOJME_01400 3.2e-78 sptS 2.7.13.3 T Histidine kinase
MBEFOJME_01401 4.9e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MBEFOJME_01402 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MBEFOJME_01403 5.3e-161 cvfB S Protein conserved in bacteria
MBEFOJME_01404 7.4e-35 yozE S Belongs to the UPF0346 family
MBEFOJME_01405 4.3e-117 sip M LysM domain protein
MBEFOJME_01406 1e-190 phoH T phosphate starvation-inducible protein PhoH
MBEFOJME_01410 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MBEFOJME_01411 1.8e-164 K transcriptional regulator (lysR family)
MBEFOJME_01412 1.4e-186 coiA 3.6.4.12 S Competence protein
MBEFOJME_01413 0.0 pepF E oligoendopeptidase F
MBEFOJME_01414 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
MBEFOJME_01415 1.1e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
MBEFOJME_01416 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MBEFOJME_01417 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MBEFOJME_01418 2.9e-153 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
MBEFOJME_01419 1.8e-30 3.4.17.14, 3.5.1.28 NU amidase activity
MBEFOJME_01420 7.9e-88 3.4.17.14, 3.5.1.28 NU amidase activity
MBEFOJME_01421 1.2e-146 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MBEFOJME_01422 5.3e-228 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
MBEFOJME_01423 1.5e-191 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MBEFOJME_01424 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MBEFOJME_01425 1.9e-130 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MBEFOJME_01426 4.8e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MBEFOJME_01427 4.1e-132 yxkH G deacetylase
MBEFOJME_01428 1.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MBEFOJME_01429 2.8e-154 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MBEFOJME_01430 1.2e-152 rarD S Transporter
MBEFOJME_01431 2.2e-15 T peptidase
MBEFOJME_01432 8.9e-14 coiA 3.6.4.12 S Competence protein
MBEFOJME_01433 4.1e-112 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MBEFOJME_01434 8.3e-75 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MBEFOJME_01435 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MBEFOJME_01436 6e-118 S Domain of unknown function (DUF1837)
MBEFOJME_01437 1.9e-07
MBEFOJME_01442 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MBEFOJME_01443 1.2e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MBEFOJME_01444 5.5e-36 XK27_02060 S Transglycosylase associated protein
MBEFOJME_01445 2.6e-55 badR K DNA-binding transcription factor activity
MBEFOJME_01446 3.5e-97 S reductase
MBEFOJME_01447 1.1e-33 L Integrase core domain protein
MBEFOJME_01448 6.5e-31
MBEFOJME_01449 1e-39
MBEFOJME_01454 6.4e-136 HJ the current gene model (or a revised gene model) may contain a frame shift
MBEFOJME_01455 1.2e-126 gltT C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MBEFOJME_01456 2.5e-13 2.3.1.82 M Acetyltransferase GNAT Family
MBEFOJME_01457 3.3e-46 K Putative DNA-binding domain
MBEFOJME_01458 3.4e-155 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MBEFOJME_01459 0.0 KLT serine threonine protein kinase
MBEFOJME_01460 2.1e-280 V ABC transporter
MBEFOJME_01461 2.7e-12 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MBEFOJME_01462 1.4e-127 Z012_04635 K sequence-specific DNA binding
MBEFOJME_01464 6.3e-16 C Radical SAM
MBEFOJME_01466 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
MBEFOJME_01467 6.4e-108 S Domain of unknown function (DUF1803)
MBEFOJME_01468 7.8e-102 ygaC J Belongs to the UPF0374 family
MBEFOJME_01469 1.2e-130 recX 2.4.1.337 GT4 S Regulatory protein RecX
MBEFOJME_01470 6.7e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MBEFOJME_01471 2.3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
MBEFOJME_01473 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MBEFOJME_01474 9.1e-220 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MBEFOJME_01475 1.7e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
MBEFOJME_01476 3.7e-54 hsdS 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
MBEFOJME_01477 1.7e-111 hsdM 2.1.1.72 V type I restriction-modification system
MBEFOJME_01478 3.7e-157 glcU U Glucose uptake
MBEFOJME_01479 3.1e-159 amiA E ABC transporter, substrate-binding protein, family 5
MBEFOJME_01480 0.0 copB 3.6.3.4 P haloacid dehalogenase-like hydrolase
MBEFOJME_01481 4.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
MBEFOJME_01482 6.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MBEFOJME_01483 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MBEFOJME_01484 2.8e-108 3.1.3.18 S IA, variant 1
MBEFOJME_01485 2.2e-117 lrgB M effector of murein hydrolase
MBEFOJME_01486 1.7e-55 lrgA S Effector of murein hydrolase LrgA
MBEFOJME_01488 6.4e-60 arsC 1.20.4.1 P Belongs to the ArsC family
MBEFOJME_01489 3.1e-56 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
MBEFOJME_01490 7e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MBEFOJME_01491 3.9e-104 wecD M Acetyltransferase GNAT family
MBEFOJME_01492 1.3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MBEFOJME_01493 5.1e-96 GK ROK family
MBEFOJME_01494 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
MBEFOJME_01495 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
MBEFOJME_01496 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
MBEFOJME_01497 2.3e-206 potD P spermidine putrescine ABC transporter
MBEFOJME_01498 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
MBEFOJME_01499 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
MBEFOJME_01500 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MBEFOJME_01501 7.8e-171 murB 1.3.1.98 M cell wall formation
MBEFOJME_01502 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MBEFOJME_01503 1.2e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MBEFOJME_01504 1.2e-298 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MBEFOJME_01505 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MBEFOJME_01506 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
MBEFOJME_01507 0.0 ydaO E amino acid
MBEFOJME_01508 1.1e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MBEFOJME_01509 4.1e-37 ylqC L Belongs to the UPF0109 family
MBEFOJME_01510 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MBEFOJME_01511 6.9e-172 tehB 2.1.1.265 PQ tellurite resistance protein tehb
MBEFOJME_01512 8.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
MBEFOJME_01513 2.1e-74 S QueT transporter
MBEFOJME_01514 1.9e-55 L Transposase
MBEFOJME_01515 5.7e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MBEFOJME_01516 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MBEFOJME_01517 3.7e-85 ccl S cog cog4708
MBEFOJME_01518 7.4e-164 rbn E Belongs to the UPF0761 family
MBEFOJME_01519 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
MBEFOJME_01520 3.3e-231 ytoI K transcriptional regulator containing CBS domains
MBEFOJME_01521 2.4e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
MBEFOJME_01522 1e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MBEFOJME_01523 0.0 comEC S Competence protein ComEC
MBEFOJME_01524 3e-98 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
MBEFOJME_01525 3.7e-142 plsC 2.3.1.51 I Acyltransferase
MBEFOJME_01526 6e-78 nodB3 G polysaccharide deacetylase
MBEFOJME_01527 4.1e-22 nodB3 G polysaccharide deacetylase
MBEFOJME_01528 2.3e-139 yabB 2.1.1.223 L Methyltransferase
MBEFOJME_01529 1e-41 yazA L endonuclease containing a URI domain
MBEFOJME_01530 3.2e-252 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MBEFOJME_01531 2.3e-154 corA P CorA-like protein
MBEFOJME_01532 1.9e-62 yjqA S Bacterial PH domain
MBEFOJME_01533 7.8e-100 thiT S Thiamine transporter
MBEFOJME_01534 8e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MBEFOJME_01535 1.9e-201 yjbB G Permeases of the major facilitator superfamily
MBEFOJME_01536 3.1e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MBEFOJME_01537 1.4e-121 ywaF S Integral membrane protein (intg_mem_TP0381)
MBEFOJME_01538 3e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MBEFOJME_01542 1.1e-155 cjaA ET ABC transporter substrate-binding protein
MBEFOJME_01543 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBEFOJME_01544 1.3e-114 P ABC transporter (Permease
MBEFOJME_01545 6.6e-114 papP P ABC transporter (Permease
MBEFOJME_01546 1.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MBEFOJME_01547 4.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
MBEFOJME_01548 0.0 copA 3.6.3.54 P P-type ATPase
MBEFOJME_01549 2.7e-73 copY K Copper transport repressor, CopY TcrY family
MBEFOJME_01550 4.6e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MBEFOJME_01551 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MBEFOJME_01552 3.3e-98 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
MBEFOJME_01553 3.2e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MBEFOJME_01554 7.8e-180 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MBEFOJME_01555 1.2e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
MBEFOJME_01556 2.2e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MBEFOJME_01557 1.8e-41 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
MBEFOJME_01558 3.2e-56
MBEFOJME_01559 0.0 ctpE P E1-E2 ATPase
MBEFOJME_01560 6.2e-28
MBEFOJME_01561 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MBEFOJME_01562 9.7e-28 L transposase activity
MBEFOJME_01563 9.2e-122 K transcriptional regulator, MerR family
MBEFOJME_01564 1.2e-103 dnaQ 2.7.7.7 L DNA polymerase III
MBEFOJME_01565 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
MBEFOJME_01566 1.6e-63 XK27_02560 S cog cog2151
MBEFOJME_01567 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MBEFOJME_01568 1.5e-225 ytfP S Flavoprotein
MBEFOJME_01570 6.9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MBEFOJME_01571 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
MBEFOJME_01572 3e-182 ecsB U ABC transporter
MBEFOJME_01573 2.3e-133 ecsA V abc transporter atp-binding protein
MBEFOJME_01574 3.3e-71 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MBEFOJME_01575 2.3e-10
MBEFOJME_01576 2.7e-57 S CD20-like family
MBEFOJME_01577 2e-104
MBEFOJME_01578 1.9e-46 L transposase activity
MBEFOJME_01579 3.2e-42 L Transposase
MBEFOJME_01580 2e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MBEFOJME_01581 3e-92 S MucBP domain
MBEFOJME_01582 1.9e-49 M YSIRK type signal peptide
MBEFOJME_01583 1.2e-165 L integrase core domain
MBEFOJME_01584 3.9e-122 L Transposase
MBEFOJME_01585 1.6e-249 L Transposase
MBEFOJME_01586 1.9e-50 L Helix-turn-helix domain
MBEFOJME_01587 5.1e-114 L Integrase core domain protein
MBEFOJME_01588 6.5e-34 L Integrase core domain protein
MBEFOJME_01591 5.4e-19 L Integrase core domain
MBEFOJME_01592 5.3e-35 hrtB V ABC transporter (Permease
MBEFOJME_01594 2.6e-101 S Domain of Unknown Function with PDB structure (DUF3862)
MBEFOJME_01595 6.1e-70 M Pfam SNARE associated Golgi protein
MBEFOJME_01596 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
MBEFOJME_01597 9.3e-59 S oxidoreductase
MBEFOJME_01598 9.7e-66 S oxidoreductase
MBEFOJME_01599 3.7e-48 XK27_09445 S Domain of unknown function (DUF1827)
MBEFOJME_01600 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MBEFOJME_01601 0.0 clpE O Belongs to the ClpA ClpB family
MBEFOJME_01602 6.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MBEFOJME_01603 1.3e-34 ykuJ S protein conserved in bacteria
MBEFOJME_01604 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
MBEFOJME_01605 4.2e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBEFOJME_01606 1.1e-78 feoA P FeoA domain protein
MBEFOJME_01607 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MBEFOJME_01608 6.6e-08
MBEFOJME_01609 1.5e-35 yugF I carboxylic ester hydrolase activity
MBEFOJME_01610 7.5e-23 I Alpha/beta hydrolase family
MBEFOJME_01611 3.9e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MBEFOJME_01612 7.8e-149 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MBEFOJME_01613 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
MBEFOJME_01614 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MBEFOJME_01615 1.7e-63 licT K transcriptional antiterminator
MBEFOJME_01616 6.8e-53 licT K transcriptional antiterminator
MBEFOJME_01617 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MBEFOJME_01618 1.7e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MBEFOJME_01619 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MBEFOJME_01620 1.9e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MBEFOJME_01621 1.1e-104 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MBEFOJME_01622 2.5e-220 mdtG EGP Major facilitator Superfamily
MBEFOJME_01623 2e-33 secG U Preprotein translocase subunit SecG
MBEFOJME_01624 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MBEFOJME_01625 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MBEFOJME_01626 9.6e-277 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MBEFOJME_01627 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
MBEFOJME_01628 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
MBEFOJME_01629 4.4e-183 ccpA K Catabolite control protein A
MBEFOJME_01630 6.2e-21 yyaQ S YjbR
MBEFOJME_01631 8.4e-142 yyaQ S YjbR
MBEFOJME_01632 1.6e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MBEFOJME_01633 1e-78 yueI S Protein of unknown function (DUF1694)
MBEFOJME_01634 9.6e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MBEFOJME_01635 2e-25 WQ51_00785
MBEFOJME_01636 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MBEFOJME_01637 2e-219 ywbD 2.1.1.191 J Methyltransferase
MBEFOJME_01638 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MBEFOJME_01639 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MBEFOJME_01640 1.3e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MBEFOJME_01641 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MBEFOJME_01642 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MBEFOJME_01643 3.2e-53 yheA S Belongs to the UPF0342 family
MBEFOJME_01644 3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MBEFOJME_01645 1.4e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MBEFOJME_01646 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MBEFOJME_01647 2.3e-153 pheA 4.2.1.51 E Prephenate dehydratase
MBEFOJME_01648 6.4e-252 msrR K Transcriptional regulator
MBEFOJME_01649 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
MBEFOJME_01650 2.4e-203 I acyl-CoA dehydrogenase
MBEFOJME_01651 5.9e-97 mip S hydroperoxide reductase activity
MBEFOJME_01652 2.8e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MBEFOJME_01653 8.9e-20
MBEFOJME_01654 2.7e-45
MBEFOJME_01655 1e-31 K Cro/C1-type HTH DNA-binding domain
MBEFOJME_01656 7.8e-50 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
MBEFOJME_01657 5.7e-34 estA E GDSL-like Lipase/Acylhydrolase
MBEFOJME_01658 3.3e-96
MBEFOJME_01659 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MBEFOJME_01660 3.2e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBEFOJME_01661 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MBEFOJME_01662 1.3e-185 S CRISPR-associated protein Csn2 subfamily St
MBEFOJME_01663 2.9e-148 ycgQ S TIGR03943 family
MBEFOJME_01664 2.4e-156 XK27_03015 S permease
MBEFOJME_01666 0.0 yhgF K Transcriptional accessory protein
MBEFOJME_01667 9.9e-42 pspC KT PspC domain
MBEFOJME_01668 1e-170 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MBEFOJME_01669 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MBEFOJME_01671 5.5e-69 ytxH S General stress protein
MBEFOJME_01673 2e-177 yegQ O Peptidase U32
MBEFOJME_01674 6.4e-251 yegQ O Peptidase U32
MBEFOJME_01675 8.1e-46 S CHY zinc finger
MBEFOJME_01676 1e-102 L Transposase
MBEFOJME_01677 1e-61 L PFAM Integrase, catalytic core
MBEFOJME_01679 3.6e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MBEFOJME_01680 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MBEFOJME_01681 3.9e-237 dltB M Membrane protein involved in D-alanine export
MBEFOJME_01682 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MBEFOJME_01683 1.7e-09 S D-Ala-teichoic acid biosynthesis protein
MBEFOJME_01684 0.0 XK27_10035 V abc transporter atp-binding protein
MBEFOJME_01685 0.0 yfiB1 V abc transporter atp-binding protein
MBEFOJME_01686 6.6e-105 pvaA M lytic transglycosylase activity
MBEFOJME_01687 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
MBEFOJME_01688 1.8e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MBEFOJME_01689 9.7e-109 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MBEFOJME_01690 1.8e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MBEFOJME_01691 3e-193 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MBEFOJME_01692 4.5e-111 tdk 2.7.1.21 F thymidine kinase
MBEFOJME_01693 4.6e-188 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MBEFOJME_01694 8.9e-155 gst O Glutathione S-transferase
MBEFOJME_01695 1e-184 nrnA 3.1.13.3, 3.1.3.7 S domain protein
MBEFOJME_01696 9.8e-177 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MBEFOJME_01697 2e-45 rpmE2 J 50S ribosomal protein L31
MBEFOJME_01698 4.3e-214 mntH P Mn2 and Fe2 transporters of the NRAMP family
MBEFOJME_01699 2.5e-09
MBEFOJME_01700 5.5e-30
MBEFOJME_01701 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MBEFOJME_01702 1.8e-135 divIVA D Cell division protein DivIVA
MBEFOJME_01703 6.1e-143 ylmH T S4 RNA-binding domain
MBEFOJME_01704 2e-34 yggT D integral membrane protein
MBEFOJME_01705 6.8e-96 sepF D cell septum assembly
MBEFOJME_01706 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MBEFOJME_01707 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MBEFOJME_01708 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MBEFOJME_01709 1.8e-177 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MBEFOJME_01710 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MBEFOJME_01711 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MBEFOJME_01713 0.0 typA T GTP-binding protein TypA
MBEFOJME_01714 2.2e-179 glk 2.7.1.2 G Glucokinase
MBEFOJME_01715 8.4e-28 yqgQ S protein conserved in bacteria
MBEFOJME_01716 1.1e-80 perR P Belongs to the Fur family
MBEFOJME_01717 3.2e-92 dps P Belongs to the Dps family
MBEFOJME_01718 4.4e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MBEFOJME_01719 2e-186 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
MBEFOJME_01720 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
MBEFOJME_01721 1.2e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
MBEFOJME_01722 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MBEFOJME_01723 6.2e-56 S Domain of unknown function (DUF4430)
MBEFOJME_01724 4.2e-75 S Psort location CytoplasmicMembrane, score
MBEFOJME_01725 2.3e-130 htpX O Belongs to the peptidase M48B family
MBEFOJME_01726 1.3e-91 lemA S LemA family
MBEFOJME_01727 4.9e-174 spd F DNA RNA non-specific endonuclease
MBEFOJME_01728 3.9e-38
MBEFOJME_01729 2.5e-44
MBEFOJME_01730 3.3e-131 3.1.21.3 V type I restriction modification DNA specificity domain
MBEFOJME_01731 7.3e-289 hsdM 2.1.1.72 V N-6 DNA Methylase
MBEFOJME_01732 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
MBEFOJME_01733 4.8e-34 MA20_36090 S Protein of unknown function (DUF2974)
MBEFOJME_01734 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MBEFOJME_01735 2.7e-27 P Hemerythrin HHE cation binding domain protein
MBEFOJME_01736 2e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
MBEFOJME_01737 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MBEFOJME_01738 2.8e-114 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
MBEFOJME_01739 7.5e-174 S hydrolase
MBEFOJME_01740 7.6e-16
MBEFOJME_01741 1e-163 M LysM domain
MBEFOJME_01742 9.9e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MBEFOJME_01743 0.0 L helicase
MBEFOJME_01744 1.3e-66 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
MBEFOJME_01745 4e-10
MBEFOJME_01746 7.8e-236 mntH P H( )-stimulated, divalent metal cation uptake system
MBEFOJME_01747 1.1e-33 XK27_12190 S protein conserved in bacteria
MBEFOJME_01749 8.4e-88 bioY S biotin synthase
MBEFOJME_01758 6.9e-09 L transposition
MBEFOJME_01759 1.3e-11 L transposition
MBEFOJME_01761 0.0 M family 8
MBEFOJME_01762 2.7e-09
MBEFOJME_01763 5.6e-08
MBEFOJME_01764 5.8e-109 MA20_06410 E LysE type translocator
MBEFOJME_01765 2.7e-12 IQ PFAM AMP-dependent synthetase and ligase
MBEFOJME_01766 5.3e-12 IQ PFAM AMP-dependent synthetase and ligase
MBEFOJME_01767 1e-137
MBEFOJME_01768 1.8e-270 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MBEFOJME_01769 4.5e-61
MBEFOJME_01771 9.3e-72 S Signal peptide protein, YSIRK family
MBEFOJME_01772 2.2e-42 K response regulator
MBEFOJME_01773 1.1e-37 BP1961 P nitric oxide dioxygenase activity
MBEFOJME_01775 6.6e-284 XK27_07020 S Belongs to the UPF0371 family
MBEFOJME_01776 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
MBEFOJME_01777 0.0 L DEAD-like helicases superfamily
MBEFOJME_01778 6.8e-139 S Abortive infection C-terminus
MBEFOJME_01779 1.5e-08
MBEFOJME_01780 1.9e-100 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MBEFOJME_01781 6.8e-161 yvgN C reductase
MBEFOJME_01782 2.3e-108 yoaK S Protein of unknown function (DUF1275)
MBEFOJME_01783 1.4e-110 drgA C Nitroreductase
MBEFOJME_01784 2e-228 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MBEFOJME_01785 9.5e-158 E Alpha/beta hydrolase of unknown function (DUF915)
MBEFOJME_01786 5.6e-77 ywnA K Transcriptional regulator
MBEFOJME_01787 9.5e-150 1.13.11.2 S glyoxalase
MBEFOJME_01788 7.4e-109 XK27_02070 S nitroreductase
MBEFOJME_01789 6.2e-228 yfnA E amino acid
MBEFOJME_01791 9.6e-26 csbD K CsbD-like
MBEFOJME_01792 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
MBEFOJME_01793 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
MBEFOJME_01794 1.7e-235 brnQ E Component of the transport system for branched-chain amino acids
MBEFOJME_01795 1.3e-187 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MBEFOJME_01796 4.5e-247 norM V Multidrug efflux pump
MBEFOJME_01797 9.2e-119 pbuX F xanthine permease
MBEFOJME_01798 1.5e-69 pbuX F xanthine permease
MBEFOJME_01800 3.2e-78 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MBEFOJME_01801 4.6e-123 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBEFOJME_01802 6.2e-166 T Histidine kinase
MBEFOJME_01803 1.9e-133 macB2 V ABC transporter, ATP-binding protein
MBEFOJME_01804 0.0 V ABC transporter (permease)
MBEFOJME_01805 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
MBEFOJME_01806 3.8e-29 liaI KT membrane
MBEFOJME_01807 3.1e-15 liaI KT membrane
MBEFOJME_01808 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
MBEFOJME_01809 2.4e-121 S An automated process has identified a potential problem with this gene model
MBEFOJME_01811 4.6e-42 3.6.1.55 F NUDIX domain
MBEFOJME_01812 3.5e-152 mutR K Transcriptional activator, Rgg GadR MutR family
MBEFOJME_01813 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
MBEFOJME_01814 3.3e-212 EGP Major facilitator Superfamily
MBEFOJME_01818 1.6e-157 XK27_09825 V abc transporter atp-binding protein
MBEFOJME_01819 2.6e-132 yvfS V ABC-2 type transporter
MBEFOJME_01820 1.5e-192 desK 2.7.13.3 T Histidine kinase
MBEFOJME_01821 4.4e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MBEFOJME_01822 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
MBEFOJME_01823 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MBEFOJME_01824 1.6e-205 S Protein of unknown function (DUF917)
MBEFOJME_01825 2.6e-280 hutH 4.3.1.3 E Histidine ammonia-lyase
MBEFOJME_01826 8.7e-111 proWZ P ABC transporter (Permease
MBEFOJME_01827 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
MBEFOJME_01828 1.5e-138 proV E abc transporter atp-binding protein
MBEFOJME_01829 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
MBEFOJME_01830 1.8e-13 bioY S biotin synthase
MBEFOJME_01831 3.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
MBEFOJME_01832 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MBEFOJME_01833 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MBEFOJME_01834 2e-129 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
MBEFOJME_01835 1.5e-119 yfeJ 6.3.5.2 F glutamine amidotransferase
MBEFOJME_01836 7.3e-41 clcA_2 P chloride
MBEFOJME_01837 3.8e-42 clcA_2 P chloride channel
MBEFOJME_01838 5.8e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MBEFOJME_01839 1.3e-41 S Protein of unknown function (DUF1697)
MBEFOJME_01840 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MBEFOJME_01841 5e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MBEFOJME_01843 4e-21 V Glucan-binding protein C
MBEFOJME_01844 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
MBEFOJME_01845 1.3e-273 pepV 3.5.1.18 E Dipeptidase
MBEFOJME_01846 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MBEFOJME_01847 8.6e-23 XK27_03610 K Gnat family
MBEFOJME_01848 1.6e-24 L Transposase
MBEFOJME_01849 5.8e-42 L Transposase
MBEFOJME_01850 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MBEFOJME_01851 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MBEFOJME_01852 3.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MBEFOJME_01853 2.5e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MBEFOJME_01854 2.8e-18 M LysM domain
MBEFOJME_01855 2.9e-90 ebsA S Family of unknown function (DUF5322)
MBEFOJME_01856 1.1e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MBEFOJME_01857 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MBEFOJME_01858 2.4e-223 G COG0457 FOG TPR repeat
MBEFOJME_01859 6.2e-176 yubA S permease
MBEFOJME_01860 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
MBEFOJME_01861 3.6e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MBEFOJME_01862 2.5e-124 ftsE D cell division ATP-binding protein FtsE
MBEFOJME_01863 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MBEFOJME_01864 2.3e-201 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MBEFOJME_01865 1.9e-180 yjjH S Calcineurin-like phosphoesterase
MBEFOJME_01866 5.2e-136 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MBEFOJME_01867 0.0 pacL 3.6.3.8 P cation transport ATPase
MBEFOJME_01868 2.6e-67 ywiB S Domain of unknown function (DUF1934)
MBEFOJME_01869 6.3e-51 XK27_00115 2.3.1.128 K acetyltransferase
MBEFOJME_01870 9.2e-147 yidA S hydrolases of the HAD superfamily
MBEFOJME_01871 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
MBEFOJME_01872 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
MBEFOJME_01873 1.4e-245 vicK 2.7.13.3 T Histidine kinase
MBEFOJME_01874 2.9e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MBEFOJME_01875 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
MBEFOJME_01876 4.5e-149 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
MBEFOJME_01877 7.7e-118 gltJ P ABC transporter (Permease
MBEFOJME_01878 4.2e-110 tcyB_2 P ABC transporter (permease)
MBEFOJME_01879 2.4e-124 endA F DNA RNA non-specific endonuclease
MBEFOJME_01880 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
MBEFOJME_01881 1.1e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MBEFOJME_01883 2.7e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MBEFOJME_01884 5.9e-26 G Domain of unknown function (DUF4832)
MBEFOJME_01885 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MBEFOJME_01886 1.2e-174 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MBEFOJME_01887 4.1e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MBEFOJME_01888 1.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MBEFOJME_01889 4.2e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MBEFOJME_01890 7.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
MBEFOJME_01891 7.7e-35
MBEFOJME_01894 5.4e-203 S Phage integrase family
MBEFOJME_01896 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MBEFOJME_01897 6.1e-219 XK27_05110 P chloride
MBEFOJME_01898 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
MBEFOJME_01899 1.3e-282 clcA P Chloride transporter, ClC family
MBEFOJME_01900 2.3e-75 fld C Flavodoxin
MBEFOJME_01901 3.3e-14 XK27_08880
MBEFOJME_01902 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
MBEFOJME_01903 1e-150 estA CE1 S Putative esterase
MBEFOJME_01904 2.3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MBEFOJME_01905 4.4e-135 XK27_08845 S abc transporter atp-binding protein
MBEFOJME_01906 2e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
MBEFOJME_01907 9.5e-178 XK27_08835 S ABC transporter substrate binding protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)