ORF_ID e_value Gene_name EC_number CAZy COGs Description
KCOEDOJP_00001 3.7e-179 scrR K Transcriptional
KCOEDOJP_00002 6e-290 scrB 3.2.1.26 GH32 G invertase
KCOEDOJP_00003 0.0 scrA 2.7.1.211 G pts system
KCOEDOJP_00004 4.1e-172 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
KCOEDOJP_00005 3.7e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCOEDOJP_00007 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KCOEDOJP_00008 3.8e-198 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCOEDOJP_00009 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KCOEDOJP_00010 4.1e-62 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KCOEDOJP_00011 6.4e-183 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KCOEDOJP_00012 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KCOEDOJP_00014 9.4e-172 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KCOEDOJP_00015 1.6e-260 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
KCOEDOJP_00016 1.1e-16 yebC M Membrane
KCOEDOJP_00017 8.3e-79 yebC M Membrane
KCOEDOJP_00018 9.1e-18 KT response to antibiotic
KCOEDOJP_00019 9.3e-31 KT response to antibiotic
KCOEDOJP_00020 1.2e-30 KT response to antibiotic
KCOEDOJP_00021 7e-10 XK27_02470 K LytTr DNA-binding domain protein
KCOEDOJP_00022 2.4e-55 liaI S membrane
KCOEDOJP_00023 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
KCOEDOJP_00024 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KCOEDOJP_00025 1.6e-11 S Protein of unknown function (DUF554)
KCOEDOJP_00026 8.5e-32 S Protein of unknown function (DUF554)
KCOEDOJP_00027 2.5e-47 S Protein of unknown function (DUF554)
KCOEDOJP_00028 1.4e-133 ecsA_2 V abc transporter atp-binding protein
KCOEDOJP_00029 6.2e-288 XK27_00765
KCOEDOJP_00030 5.7e-141 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KCOEDOJP_00031 2e-225 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KCOEDOJP_00032 1.3e-08 D nuclear chromosome segregation
KCOEDOJP_00033 8.7e-33 yhaI J Protein of unknown function (DUF805)
KCOEDOJP_00034 8.5e-111
KCOEDOJP_00035 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KCOEDOJP_00036 1.2e-46 ftsL D cell division protein FtsL
KCOEDOJP_00037 0.0 ftsI 3.4.16.4 M penicillin-binding protein
KCOEDOJP_00038 6.3e-185 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KCOEDOJP_00039 4.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KCOEDOJP_00041 5.1e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KCOEDOJP_00042 3.6e-70 yutD J protein conserved in bacteria
KCOEDOJP_00043 5.6e-222 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KCOEDOJP_00044 1.7e-93 XK27_09885 V Glycopeptide antibiotics resistance protein
KCOEDOJP_00046 0.0 mdlA V abc transporter atp-binding protein
KCOEDOJP_00047 0.0 mdlB V abc transporter atp-binding protein
KCOEDOJP_00048 2.8e-108 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCOEDOJP_00049 1.3e-279 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCOEDOJP_00050 6.2e-236 mesE M Transport protein ComB
KCOEDOJP_00052 1.3e-238 blpH 2.7.13.3 T protein histidine kinase activity
KCOEDOJP_00053 8.9e-133 agrA KT phosphorelay signal transduction system
KCOEDOJP_00056 4.3e-25 S Bacteriocin class II with double-glycine leader peptide
KCOEDOJP_00065 9.5e-140 blpT
KCOEDOJP_00066 3e-47 spiA K sequence-specific DNA binding
KCOEDOJP_00069 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KCOEDOJP_00070 2e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KCOEDOJP_00071 5e-44 V CAAX protease self-immunity
KCOEDOJP_00072 4.6e-140 cppA E CppA N-terminal
KCOEDOJP_00073 4.5e-185 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
KCOEDOJP_00074 1.2e-117 ybbL S abc transporter atp-binding protein
KCOEDOJP_00075 1.5e-127 ybbM S transport system, permease component
KCOEDOJP_00076 9.3e-124 XK27_05540 S Gram-negative-bacterium-type cell wall biogenesis
KCOEDOJP_00077 2.7e-32 L DNA integration
KCOEDOJP_00078 2.9e-87 D nuclear chromosome segregation
KCOEDOJP_00079 1e-44 hsdS_1 3.1.21.3 V type I restriction modification DNA specificity domain
KCOEDOJP_00080 2.1e-85 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCOEDOJP_00081 4.8e-41 cah 4.2.1.1 P carbonate dehydratase activity
KCOEDOJP_00082 7.5e-62 cah 4.2.1.1 P carbonic anhydrase
KCOEDOJP_00083 0.0 pflB 2.3.1.54 C formate acetyltransferase'
KCOEDOJP_00084 2.3e-201 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCOEDOJP_00086 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCOEDOJP_00087 4.7e-163 yxeN P ABC transporter (Permease
KCOEDOJP_00088 6.5e-131 tcyN 3.6.3.21 E abc transporter atp-binding protein
KCOEDOJP_00089 3.2e-09 S Protein of unknown function (DUF4059)
KCOEDOJP_00090 1.9e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KCOEDOJP_00091 5.1e-93 rsmD 2.1.1.171 L Methyltransferase
KCOEDOJP_00092 2.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KCOEDOJP_00093 8.4e-196 ylbL T Belongs to the peptidase S16 family
KCOEDOJP_00094 8.4e-184 yhcC S radical SAM protein
KCOEDOJP_00095 1.4e-98 ytqB 2.1.1.176 J (SAM)-dependent
KCOEDOJP_00097 0.0 yjcE P NhaP-type Na H and K H antiporters
KCOEDOJP_00098 3.5e-117 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KCOEDOJP_00099 2.6e-08 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
KCOEDOJP_00100 7.6e-239 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
KCOEDOJP_00101 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCOEDOJP_00103 6.9e-75 XK27_03180 T universal stress protein
KCOEDOJP_00104 1.1e-239 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
KCOEDOJP_00105 1.2e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KCOEDOJP_00106 6.8e-101 pncA Q isochorismatase
KCOEDOJP_00107 3.7e-154 hlpA M Belongs to the NlpA lipoprotein family
KCOEDOJP_00108 3.6e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCOEDOJP_00109 1e-234 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCOEDOJP_00110 2.4e-30 M lipopolysaccharide 3-alpha-galactosyltransferase activity
KCOEDOJP_00111 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCOEDOJP_00112 1.6e-269 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KCOEDOJP_00113 7.8e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KCOEDOJP_00114 1.2e-58
KCOEDOJP_00115 3.7e-152 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KCOEDOJP_00116 1.8e-98 yqeG S hydrolase of the HAD superfamily
KCOEDOJP_00117 4.9e-215 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KCOEDOJP_00118 3.5e-49 yhbY J RNA-binding protein
KCOEDOJP_00119 3.1e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KCOEDOJP_00120 1.4e-107 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KCOEDOJP_00121 1.3e-57 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KCOEDOJP_00122 2e-140 yqeM Q Methyltransferase domain protein
KCOEDOJP_00123 1.9e-200 ylbM S Belongs to the UPF0348 family
KCOEDOJP_00124 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
KCOEDOJP_00125 3.2e-110
KCOEDOJP_00126 1.3e-56 S CD20-like family
KCOEDOJP_00127 2.3e-10
KCOEDOJP_00128 3.9e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KCOEDOJP_00129 2.3e-133 ecsA V abc transporter atp-binding protein
KCOEDOJP_00130 5.1e-182 ecsB U ABC transporter
KCOEDOJP_00131 1.2e-151 ytmP 2.7.1.89 M Phosphotransferase
KCOEDOJP_00132 3.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KCOEDOJP_00134 2.2e-226 ytfP S Flavoprotein
KCOEDOJP_00135 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCOEDOJP_00136 1.6e-63 XK27_02560 S cog cog2151
KCOEDOJP_00137 1.2e-41 WQ51_02910 S Protein of unknown function, DUF536
KCOEDOJP_00138 5e-102 dnaQ 2.7.7.7 L DNA polymerase III
KCOEDOJP_00139 3.5e-121 K transcriptional regulator, MerR family
KCOEDOJP_00140 2.1e-28 L transposase activity
KCOEDOJP_00141 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KCOEDOJP_00142 3.8e-86 L Belongs to the 'phage' integrase family
KCOEDOJP_00143 1.1e-81 L Belongs to the 'phage' integrase family
KCOEDOJP_00144 4.8e-14 S Domain of unknown function (DUF3173)
KCOEDOJP_00145 9.5e-18 isp2 S pathogenesis
KCOEDOJP_00146 7.4e-14 isp2 S pathogenesis
KCOEDOJP_00147 9.2e-24 isp2 S pathogenesis
KCOEDOJP_00148 1.3e-10 L NgoFVII restriction endonuclease
KCOEDOJP_00149 1.2e-133 L NgoFVII restriction endonuclease
KCOEDOJP_00150 1.1e-159 dcm 2.1.1.37 H PFAM C-5 cytosine-specific DNA methylase
KCOEDOJP_00151 4.4e-176 dcm_2 2.1.1.37 L C-5 cytosine-specific DNA methylase
KCOEDOJP_00153 1.8e-17
KCOEDOJP_00154 3.6e-44
KCOEDOJP_00155 4.2e-110
KCOEDOJP_00156 1.1e-128 S Protein conserved in bacteria
KCOEDOJP_00158 6.1e-27
KCOEDOJP_00159 0.0 ctpE P E1-E2 ATPase
KCOEDOJP_00160 3.2e-56
KCOEDOJP_00161 3.7e-42 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
KCOEDOJP_00162 1.4e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KCOEDOJP_00163 3.6e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
KCOEDOJP_00164 2.3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KCOEDOJP_00165 5.5e-133 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KCOEDOJP_00166 1.8e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
KCOEDOJP_00167 1.1e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KCOEDOJP_00168 2.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KCOEDOJP_00169 8e-73 copY K Copper transport repressor, CopY TcrY family
KCOEDOJP_00170 0.0 copA 3.6.3.54 P P-type ATPase
KCOEDOJP_00171 1.8e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
KCOEDOJP_00172 6.4e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCOEDOJP_00173 1e-114 papP P ABC transporter (Permease
KCOEDOJP_00174 1.3e-114 P ABC transporter (Permease
KCOEDOJP_00175 1.4e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCOEDOJP_00176 1.1e-155 cjaA ET ABC transporter substrate-binding protein
KCOEDOJP_00179 8.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KCOEDOJP_00180 4.6e-112 ywaF S Integral membrane protein (intg_mem_TP0381)
KCOEDOJP_00181 1.2e-299 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KCOEDOJP_00182 2e-197 L Transposase
KCOEDOJP_00183 1e-199 yjbB G Permeases of the major facilitator superfamily
KCOEDOJP_00184 3.6e-157 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCOEDOJP_00185 1.6e-97 thiT S Thiamine transporter
KCOEDOJP_00186 2.5e-62 yjqA S Bacterial PH domain
KCOEDOJP_00187 1e-149 corA P CorA-like protein
KCOEDOJP_00188 2.7e-251 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KCOEDOJP_00189 1e-41 yazA L endonuclease containing a URI domain
KCOEDOJP_00190 6e-140 yabB 2.1.1.223 L Methyltransferase
KCOEDOJP_00191 7.1e-137 nodB3 G deacetylase
KCOEDOJP_00192 3.7e-142 plsC 2.3.1.51 I Acyltransferase
KCOEDOJP_00193 7e-95 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
KCOEDOJP_00194 0.0 comEC S Competence protein ComEC
KCOEDOJP_00195 2.6e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCOEDOJP_00196 1.5e-97 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
KCOEDOJP_00197 3.3e-231 ytoI K transcriptional regulator containing CBS domains
KCOEDOJP_00198 1.5e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
KCOEDOJP_00199 7.4e-164 rbn E Belongs to the UPF0761 family
KCOEDOJP_00200 1.3e-85 ccl S cog cog4708
KCOEDOJP_00201 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KCOEDOJP_00202 1.9e-186 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KCOEDOJP_00203 1.7e-119 ribD 1.1.1.193, 3.5.4.26 L Transposase DDE domain
KCOEDOJP_00204 2.1e-74 S QueT transporter
KCOEDOJP_00205 1.3e-156 xth 3.1.11.2 L exodeoxyribonuclease III
KCOEDOJP_00206 2.6e-171 tehB 2.1.1.265 PQ tellurite resistance protein tehb
KCOEDOJP_00207 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KCOEDOJP_00208 4.1e-37 ylqC L Belongs to the UPF0109 family
KCOEDOJP_00209 5.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCOEDOJP_00210 6.8e-17 ydaO E amino acid
KCOEDOJP_00211 2.8e-163 ydaO E amino acid
KCOEDOJP_00212 5.7e-132 ydaO E amino acid
KCOEDOJP_00213 1e-99 folE 3.5.4.16 F gtp cyclohydrolase
KCOEDOJP_00214 7e-147 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KCOEDOJP_00215 3e-297 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
KCOEDOJP_00216 7.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KCOEDOJP_00217 2.9e-87 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KCOEDOJP_00218 7.8e-171 murB 1.3.1.98 M cell wall formation
KCOEDOJP_00219 1.2e-213 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KCOEDOJP_00220 3.7e-140 potB P ABC-type spermidine putrescine transport system, permease component I
KCOEDOJP_00221 3e-134 potC P ABC-type spermidine putrescine transport system, permease component II
KCOEDOJP_00222 2.3e-206 potD P spermidine putrescine ABC transporter
KCOEDOJP_00223 1.3e-19 XK27_08050 O HflC and HflK could regulate a protease
KCOEDOJP_00224 1.7e-47 XK27_08050 O stress-induced mitochondrial fusion
KCOEDOJP_00225 8.1e-72 gloA 4.4.1.5 E Lactoylglutathione lyase
KCOEDOJP_00226 5.1e-96 GK ROK family
KCOEDOJP_00227 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KCOEDOJP_00228 1.5e-103 wecD M Acetyltransferase GNAT family
KCOEDOJP_00229 1.1e-220 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KCOEDOJP_00230 1e-54 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
KCOEDOJP_00231 3.2e-59 arsC 1.20.4.1 P Belongs to the ArsC family
KCOEDOJP_00233 5e-55 lrgA S Effector of murein hydrolase LrgA
KCOEDOJP_00234 2.2e-117 lrgB M effector of murein hydrolase
KCOEDOJP_00235 1.3e-108 3.1.3.18 S IA, variant 1
KCOEDOJP_00236 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCOEDOJP_00237 1.6e-302 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KCOEDOJP_00238 7.4e-115 serB 3.1.3.3 E phosphoserine phosphatase
KCOEDOJP_00239 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KCOEDOJP_00240 1.5e-163 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCOEDOJP_00241 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCOEDOJP_00242 5.6e-110 csn2 S CRISPR-associated protein (Cas_Csn2)
KCOEDOJP_00244 1.7e-154 EG Permeases of the drug metabolite transporter (DMT) superfamily
KCOEDOJP_00246 3e-37 ycaO O OsmC-like protein
KCOEDOJP_00247 5.5e-65 paaI Q protein possibly involved in aromatic compounds catabolism
KCOEDOJP_00250 1.8e-133 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCOEDOJP_00252 3.7e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KCOEDOJP_00253 1.1e-16 XK27_00735
KCOEDOJP_00254 6.3e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCOEDOJP_00255 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
KCOEDOJP_00256 3.4e-32 S CAAX amino terminal protease family protein
KCOEDOJP_00258 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KCOEDOJP_00259 1.1e-83 mutT 3.6.1.55 F Nudix family
KCOEDOJP_00260 3.7e-143 ET Belongs to the bacterial solute-binding protein 3 family
KCOEDOJP_00261 9.4e-136 ET ABC transporter
KCOEDOJP_00262 2.6e-200 arcT 2.6.1.1 E Aminotransferase
KCOEDOJP_00263 1.6e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
KCOEDOJP_00264 5.5e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KCOEDOJP_00265 1.9e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KCOEDOJP_00266 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KCOEDOJP_00267 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KCOEDOJP_00268 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
KCOEDOJP_00269 1.4e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
KCOEDOJP_00270 2.1e-235 L Helix-turn-helix domain of transposase family ISL3
KCOEDOJP_00271 3.2e-245
KCOEDOJP_00272 1.2e-160 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KCOEDOJP_00273 1.9e-124 ycbB S Glycosyl transferase family 2
KCOEDOJP_00274 1.5e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
KCOEDOJP_00275 7.3e-215 amrA S polysaccharide biosynthetic process
KCOEDOJP_00276 2.3e-187 tagF 2.7.8.12 M Glycosyl transferase, family 2
KCOEDOJP_00277 7.9e-139 S Predicted membrane protein (DUF2142)
KCOEDOJP_00278 7.7e-224 rgpA GT4 M Domain of unknown function (DUF1972)
KCOEDOJP_00279 6.3e-179 rgpB GT2 M Glycosyltransferase, group 2 family protein
KCOEDOJP_00280 1.4e-142 rgpC GM Transport permease protein
KCOEDOJP_00281 3.3e-225 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KCOEDOJP_00282 3.4e-194 rgpEc GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KCOEDOJP_00283 0.0 rgpF M Rhamnan synthesis protein F
KCOEDOJP_00284 6.2e-120 radC E Belongs to the UPF0758 family
KCOEDOJP_00285 1.6e-131 puuD T peptidase C26
KCOEDOJP_00286 5.7e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KCOEDOJP_00287 9e-59 XK27_04120 S Putative amino acid metabolism
KCOEDOJP_00288 4.1e-206 iscS 2.8.1.7 E Cysteine desulfurase
KCOEDOJP_00289 2.1e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCOEDOJP_00290 7.6e-103 yjbK S Adenylate cyclase
KCOEDOJP_00291 2.1e-120 yjbM 2.7.6.5 S Gtp pyrophosphokinase
KCOEDOJP_00292 5.4e-150 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KCOEDOJP_00293 1.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KCOEDOJP_00294 5.9e-180 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KCOEDOJP_00295 8.9e-18 L transposase activity
KCOEDOJP_00296 1.1e-23 L transposase activity
KCOEDOJP_00297 1e-110 L Integrase core domain protein
KCOEDOJP_00298 6.7e-218 oxlT P COG0477 Permeases of the major facilitator superfamily
KCOEDOJP_00299 1.4e-40 tatD L Hydrolase, tatd
KCOEDOJP_00300 2.3e-23 oppF P Belongs to the ABC transporter superfamily
KCOEDOJP_00301 1.2e-24 oppF P Belongs to the ABC transporter superfamily
KCOEDOJP_00302 0.0 amiA E ABC transporter, substrate-binding protein, family 5
KCOEDOJP_00303 1.1e-270 amiC P ABC transporter (Permease
KCOEDOJP_00304 4.1e-167 amiD P ABC transporter (Permease
KCOEDOJP_00305 2.2e-204 oppD P Belongs to the ABC transporter superfamily
KCOEDOJP_00306 4.3e-172 oppF P Belongs to the ABC transporter superfamily
KCOEDOJP_00307 9.6e-133 V ATPase activity
KCOEDOJP_00308 9.8e-121 skfE V abc transporter atp-binding protein
KCOEDOJP_00309 8.6e-63 yvoA_1 K Transcriptional
KCOEDOJP_00310 5.3e-147 supH S overlaps another CDS with the same product name
KCOEDOJP_00311 1.8e-150 XK27_02985 S overlaps another CDS with the same product name
KCOEDOJP_00312 4.1e-211 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KCOEDOJP_00313 2.6e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KCOEDOJP_00314 2.7e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
KCOEDOJP_00315 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KCOEDOJP_00316 1.9e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KCOEDOJP_00317 4e-248 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KCOEDOJP_00318 9e-133 stp 3.1.3.16 T phosphatase
KCOEDOJP_00319 2.9e-305 prkC 2.7.11.1 KLT serine threonine protein kinase
KCOEDOJP_00320 9.1e-119 yvqF KT membrane
KCOEDOJP_00321 2.9e-174 vraS 2.7.13.3 T Histidine kinase
KCOEDOJP_00322 2.2e-114 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCOEDOJP_00325 5.8e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KCOEDOJP_00326 1.4e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KCOEDOJP_00327 1.1e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KCOEDOJP_00328 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KCOEDOJP_00329 4.6e-73 L Transposase
KCOEDOJP_00330 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
KCOEDOJP_00331 1.1e-40 V abc transporter atp-binding protein
KCOEDOJP_00332 5.2e-99 V abc transporter atp-binding protein
KCOEDOJP_00333 6.7e-17 rtxA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KCOEDOJP_00334 3.5e-228 zmpB M M26 IgA1-specific Metallo-endopeptidase C-terminal region
KCOEDOJP_00335 4.6e-25 L transposition
KCOEDOJP_00336 2.7e-08 L Integrase core domain protein
KCOEDOJP_00337 2.3e-184 galR K Transcriptional regulator
KCOEDOJP_00338 4.8e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KCOEDOJP_00339 7.8e-285 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KCOEDOJP_00340 6.6e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCOEDOJP_00341 6.4e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KCOEDOJP_00342 0.0 lacS G transporter
KCOEDOJP_00343 0.0 lacL 3.2.1.23 G -beta-galactosidase
KCOEDOJP_00344 1.7e-229 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KCOEDOJP_00345 0.0 sbcC L ATPase involved in DNA repair
KCOEDOJP_00346 2.8e-85
KCOEDOJP_00348 1.8e-87 L transposase activity
KCOEDOJP_00349 1.4e-150 L Integrase core domain protein
KCOEDOJP_00350 6.5e-159 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCOEDOJP_00352 5.5e-258 I radical SAM domain protein
KCOEDOJP_00353 9.8e-176 EGP Major Facilitator Superfamily
KCOEDOJP_00354 2.8e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KCOEDOJP_00355 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KCOEDOJP_00356 8.7e-220 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KCOEDOJP_00357 8.1e-59 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KCOEDOJP_00358 2.7e-48 S glycolate biosynthetic process
KCOEDOJP_00359 3.4e-64 S phosphatase activity
KCOEDOJP_00360 6.3e-159 rrmA 2.1.1.187 Q methyltransferase
KCOEDOJP_00363 7.8e-91 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KCOEDOJP_00364 5.1e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCOEDOJP_00365 6.4e-37 yeeD O sulfur carrier activity
KCOEDOJP_00366 3.6e-188 yeeE S Sulphur transport
KCOEDOJP_00367 1.8e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCOEDOJP_00368 2.7e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KCOEDOJP_00369 5.4e-09 S Domain of unknown function (DUF4651)
KCOEDOJP_00370 2e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KCOEDOJP_00371 3.9e-131 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KCOEDOJP_00372 3.9e-111 S CAAX amino terminal protease family protein
KCOEDOJP_00374 5e-67 V CAAX protease self-immunity
KCOEDOJP_00375 2.6e-26 lanR K sequence-specific DNA binding
KCOEDOJP_00376 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KCOEDOJP_00377 5.9e-177 ytxK 2.1.1.72 L DNA methylase
KCOEDOJP_00378 6.8e-13 comGF U Putative Competence protein ComGF
KCOEDOJP_00379 9.9e-71 comGF U Competence protein ComGF
KCOEDOJP_00380 1.4e-15 NU Type II secretory pathway pseudopilin
KCOEDOJP_00381 1.8e-57 cglD NU Competence protein
KCOEDOJP_00382 9.4e-42 comGC U Required for transformation and DNA binding
KCOEDOJP_00383 5.4e-156 cglB U protein transport across the cell outer membrane
KCOEDOJP_00384 2.2e-176 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KCOEDOJP_00385 2.9e-68 S cog cog4699
KCOEDOJP_00386 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCOEDOJP_00387 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCOEDOJP_00388 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCOEDOJP_00389 1.2e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KCOEDOJP_00390 1.6e-196 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KCOEDOJP_00391 7.7e-77 ilvN 2.2.1.6 E Acetolactate synthase
KCOEDOJP_00392 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
KCOEDOJP_00393 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KCOEDOJP_00394 3.5e-302 yloV S kinase related to dihydroxyacetone kinase
KCOEDOJP_00395 4e-57 asp S cog cog1302
KCOEDOJP_00396 1.1e-223 norN V Mate efflux family protein
KCOEDOJP_00397 2.4e-278 thrC 4.2.3.1 E Threonine synthase
KCOEDOJP_00398 8.8e-63 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCOEDOJP_00399 8e-35 adhE 1.1.1.1, 1.2.1.10 C hydroxyacid-oxoacid transhydrogenase activity
KCOEDOJP_00400 1.1e-65 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCOEDOJP_00401 1.3e-135 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KCOEDOJP_00402 5.3e-63 adhE 1.1.1.1, 1.2.1.10 C Dehydrogenase
KCOEDOJP_00403 0.0 pepO 3.4.24.71 O Peptidase family M13
KCOEDOJP_00404 2.8e-38 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCOEDOJP_00405 1.2e-69 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCOEDOJP_00406 5.9e-66 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KCOEDOJP_00407 1.9e-54 treB 2.7.1.201 G PTS System
KCOEDOJP_00408 5.8e-21 treR K DNA-binding transcription factor activity
KCOEDOJP_00409 8.6e-87 treR K trehalose operon
KCOEDOJP_00410 7.4e-95 ywlG S Belongs to the UPF0340 family
KCOEDOJP_00412 3.8e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KCOEDOJP_00413 9.7e-30 S Domain of unknown function (DUF4649)
KCOEDOJP_00415 1.1e-236 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
KCOEDOJP_00416 5.5e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KCOEDOJP_00417 2.8e-44 yrzL S Belongs to the UPF0297 family
KCOEDOJP_00418 1.2e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KCOEDOJP_00419 4.2e-44 yrzB S Belongs to the UPF0473 family
KCOEDOJP_00420 2.1e-299 ccs S the current gene model (or a revised gene model) may contain a frame shift
KCOEDOJP_00421 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KCOEDOJP_00422 7.5e-14
KCOEDOJP_00423 2.6e-91 XK27_10930 K acetyltransferase
KCOEDOJP_00424 1.1e-115 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KCOEDOJP_00425 3.9e-142 L Transposase
KCOEDOJP_00426 5.5e-147 yaaA S Belongs to the UPF0246 family
KCOEDOJP_00427 4.9e-168 XK27_01785 S cog cog1284
KCOEDOJP_00428 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KCOEDOJP_00430 1.6e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
KCOEDOJP_00431 5.7e-52 metE 2.1.1.14 E Methionine synthase
KCOEDOJP_00432 7.6e-64 metE 2.1.1.14 E Methionine synthase
KCOEDOJP_00433 9.2e-36 metE 2.1.1.14 E Methionine synthase
KCOEDOJP_00434 2e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KCOEDOJP_00435 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KCOEDOJP_00437 3.1e-20 yegS 2.7.1.107 I lipid kinase activity
KCOEDOJP_00438 2.7e-95 S Hydrophobic domain protein
KCOEDOJP_00440 3.7e-27 S Membrane
KCOEDOJP_00441 3.1e-101
KCOEDOJP_00442 1.8e-23 S Small integral membrane protein
KCOEDOJP_00443 1.1e-71 M Protein conserved in bacteria
KCOEDOJP_00444 4.9e-12 K CsbD-like
KCOEDOJP_00445 1.7e-96 nudL L hydrolase
KCOEDOJP_00446 3.4e-13 nudL L hydrolase
KCOEDOJP_00447 8e-49 K transcriptional regulator, PadR family
KCOEDOJP_00449 1.1e-105 S Putative adhesin
KCOEDOJP_00450 3.6e-159 XK27_06930 V domain protein
KCOEDOJP_00451 3.5e-94 XK27_06935 K transcriptional regulator
KCOEDOJP_00452 9.1e-54 ypaA S membrane
KCOEDOJP_00453 1.8e-08
KCOEDOJP_00454 9.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KCOEDOJP_00455 8.2e-48 veg S Biofilm formation stimulator VEG
KCOEDOJP_00456 1.5e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KCOEDOJP_00457 2e-69 rplI J binds to the 23S rRNA
KCOEDOJP_00458 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KCOEDOJP_00459 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KCOEDOJP_00460 8.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KCOEDOJP_00461 0.0 S Bacterial membrane protein, YfhO
KCOEDOJP_00462 1.3e-87 isaA GH23 M Immunodominant staphylococcal antigen A
KCOEDOJP_00463 1.7e-91 lytE M LysM domain protein
KCOEDOJP_00464 3.8e-137 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCOEDOJP_00465 5.2e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCOEDOJP_00466 7.5e-152 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KCOEDOJP_00467 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KCOEDOJP_00468 3.7e-138 ymfM S sequence-specific DNA binding
KCOEDOJP_00469 1.4e-242 ymfH S Peptidase M16
KCOEDOJP_00470 5.1e-156 ymfF S Peptidase M16
KCOEDOJP_00471 1.7e-66 ymfF S Peptidase M16
KCOEDOJP_00472 1.6e-45 yaaA S S4 domain protein YaaA
KCOEDOJP_00473 5.9e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KCOEDOJP_00474 3.8e-31 hmpT S membrane
KCOEDOJP_00475 1.6e-137 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
KCOEDOJP_00476 8.5e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KCOEDOJP_00477 1.1e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KCOEDOJP_00478 9.8e-298 dnaK O Heat shock 70 kDa protein
KCOEDOJP_00479 1.3e-71 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KCOEDOJP_00480 5.3e-198 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KCOEDOJP_00481 1.3e-102 acmA 3.2.1.17 NU amidase activity
KCOEDOJP_00482 1.2e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KCOEDOJP_00483 1.5e-129 ais G Phosphoglycerate mutase
KCOEDOJP_00484 1.9e-242 XK27_08635 S UPF0210 protein
KCOEDOJP_00485 3.6e-39 gcvR T UPF0237 protein
KCOEDOJP_00486 9.1e-223 capA M Bacterial capsule synthesis protein
KCOEDOJP_00487 1.5e-121 tnp L Transposase IS66 family
KCOEDOJP_00488 6.8e-76 isp2 S pathogenesis
KCOEDOJP_00490 3.7e-118
KCOEDOJP_00492 8.7e-41 S Helix-turn-helix domain
KCOEDOJP_00493 4.5e-83 int L Belongs to the 'phage' integrase family
KCOEDOJP_00494 8.5e-112 int L Belongs to the 'phage' integrase family
KCOEDOJP_00495 1.8e-70 2.7.7.49 L DNA polymerase
KCOEDOJP_00498 2.8e-09 S Sigma-70, region 4
KCOEDOJP_00499 7.4e-44
KCOEDOJP_00500 4.6e-194 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KCOEDOJP_00501 4.8e-55
KCOEDOJP_00502 5.2e-91 S Plasmid replication protein
KCOEDOJP_00503 8.3e-24
KCOEDOJP_00504 4.8e-188 L Phage integrase family
KCOEDOJP_00505 9.5e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KCOEDOJP_00506 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KCOEDOJP_00507 1.6e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KCOEDOJP_00508 4.7e-32 K helix-turn-helix
KCOEDOJP_00509 1.7e-154 degV S DegV family
KCOEDOJP_00510 3.5e-91 yacP S RNA-binding protein containing a PIN domain
KCOEDOJP_00511 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCOEDOJP_00514 5.5e-68 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KCOEDOJP_00515 1.5e-258 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCOEDOJP_00516 1.1e-112 cysE 2.3.1.30 E serine acetyltransferase
KCOEDOJP_00517 6.9e-144 S SseB protein N-terminal domain
KCOEDOJP_00518 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KCOEDOJP_00519 4.2e-231 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCOEDOJP_00520 2.1e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KCOEDOJP_00521 7.6e-123 comFC S Competence protein
KCOEDOJP_00522 1.3e-254 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KCOEDOJP_00523 6.3e-111 yvyE 3.4.13.9 S YigZ family
KCOEDOJP_00524 4.9e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KCOEDOJP_00525 4.7e-42 acuB S IMP dehydrogenase activity
KCOEDOJP_00526 2.8e-70 acuB S IMP dehydrogenase activity
KCOEDOJP_00527 1.4e-122 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
KCOEDOJP_00528 9.6e-138 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
KCOEDOJP_00529 2.4e-138 livM E Belongs to the binding-protein-dependent transport system permease family
KCOEDOJP_00530 1.9e-145 livH E Belongs to the binding-protein-dependent transport system permease family
KCOEDOJP_00531 1.2e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
KCOEDOJP_00532 7.1e-46 ylbG S UPF0298 protein
KCOEDOJP_00533 3.4e-74 ylbF S Belongs to the UPF0342 family
KCOEDOJP_00534 2.9e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KCOEDOJP_00535 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KCOEDOJP_00536 1.2e-08 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
KCOEDOJP_00538 1.1e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KCOEDOJP_00539 4.7e-202 metB 2.5.1.48, 4.4.1.8 E cystathionine
KCOEDOJP_00540 8.1e-83 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
KCOEDOJP_00541 4.5e-283 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
KCOEDOJP_00542 4.9e-276 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KCOEDOJP_00543 4.5e-233 femA 2.3.2.10, 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
KCOEDOJP_00544 3.4e-37 yvdD 3.2.2.10 L Belongs to the LOG family
KCOEDOJP_00545 2e-22 yvdD 3.2.2.10 S Belongs to the LOG family
KCOEDOJP_00546 1.7e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KCOEDOJP_00547 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KCOEDOJP_00548 1.4e-41 ylxQ J ribosomal protein
KCOEDOJP_00549 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
KCOEDOJP_00550 3.1e-212 nusA K Participates in both transcription termination and antitermination
KCOEDOJP_00551 3.9e-81 rimP S Required for maturation of 30S ribosomal subunits
KCOEDOJP_00552 3.4e-217 brpA K Transcriptional
KCOEDOJP_00553 2.4e-92 XK27_05885 2.3.1.82 M Acetyltransferase GNAT Family
KCOEDOJP_00554 1.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
KCOEDOJP_00555 8.3e-244 pbuO S permease
KCOEDOJP_00556 1e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KCOEDOJP_00557 7.5e-140 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
KCOEDOJP_00558 1.1e-181 manL 2.7.1.191 G pts system
KCOEDOJP_00559 3.9e-116 manM G pts system
KCOEDOJP_00560 9.6e-169 manN G PTS system mannose fructose sorbose family IID component
KCOEDOJP_00561 4.2e-62 manO S protein conserved in bacteria
KCOEDOJP_00562 2.1e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KCOEDOJP_00563 7.8e-28 L transposase activity
KCOEDOJP_00564 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
KCOEDOJP_00565 6.7e-133 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KCOEDOJP_00566 2.2e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KCOEDOJP_00567 1.3e-122 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KCOEDOJP_00568 3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
KCOEDOJP_00569 2.7e-31 L Transposase
KCOEDOJP_00570 2e-53 L Transposase
KCOEDOJP_00571 2.5e-15
KCOEDOJP_00572 1.2e-260 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KCOEDOJP_00573 6.1e-216 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KCOEDOJP_00574 3.1e-81 ypmB S Protein conserved in bacteria
KCOEDOJP_00575 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KCOEDOJP_00576 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KCOEDOJP_00577 4.8e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
KCOEDOJP_00578 3e-190 yufP S Belongs to the binding-protein-dependent transport system permease family
KCOEDOJP_00579 3.5e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KCOEDOJP_00580 2.6e-189 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KCOEDOJP_00581 2.2e-47 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KCOEDOJP_00582 4e-63 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCOEDOJP_00583 1.4e-22 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KCOEDOJP_00584 1.2e-98 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KCOEDOJP_00585 5.1e-23 pdp 2.4.2.2, 2.4.2.4 F phosphorylase activity
KCOEDOJP_00586 2.3e-26 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
KCOEDOJP_00587 2.4e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
KCOEDOJP_00588 1.1e-172 coaA 2.7.1.33 F Pantothenic acid kinase
KCOEDOJP_00589 2.1e-30 rpsT J rRNA binding
KCOEDOJP_00590 4.3e-124 T PhoQ Sensor
KCOEDOJP_00591 7.2e-42 T PhoQ Sensor
KCOEDOJP_00592 1.4e-39 T PhoQ Sensor
KCOEDOJP_00593 6.4e-66 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCOEDOJP_00594 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KCOEDOJP_00595 1.2e-120 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
KCOEDOJP_00596 4.8e-94 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KCOEDOJP_00597 1.1e-93 panT S ECF transporter, substrate-specific component
KCOEDOJP_00598 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KCOEDOJP_00599 1.1e-164 metF 1.5.1.20 C reductase
KCOEDOJP_00600 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KCOEDOJP_00602 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
KCOEDOJP_00603 0.0 3.6.3.8 P cation transport ATPase
KCOEDOJP_00604 3.6e-39 L Transposase
KCOEDOJP_00605 4.2e-10 L transposase activity
KCOEDOJP_00606 4.1e-167 GK ROK family
KCOEDOJP_00607 2.6e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCOEDOJP_00608 1.1e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KCOEDOJP_00609 8.1e-128 K DNA-binding helix-turn-helix protein
KCOEDOJP_00610 6e-91 niaR S small molecule binding protein (contains 3H domain)
KCOEDOJP_00611 9.1e-87 niaX
KCOEDOJP_00612 1.6e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KCOEDOJP_00613 1.1e-53 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KCOEDOJP_00614 2e-126 gntR1 K transcriptional
KCOEDOJP_00615 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KCOEDOJP_00616 8.5e-88 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
KCOEDOJP_00617 1.2e-158 sthIM 2.1.1.72 L DNA methylase
KCOEDOJP_00618 0.0 res_1 3.1.21.5 S Type III restriction
KCOEDOJP_00619 5.3e-58 adhP 1.1.1.1 C alcohol dehydrogenase
KCOEDOJP_00620 1.6e-21 adhP 1.1.1.1 C alcohol dehydrogenase
KCOEDOJP_00621 8.1e-60 adhP 1.1.1.1 C alcohol dehydrogenase
KCOEDOJP_00622 2.1e-07
KCOEDOJP_00623 1.2e-146 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCOEDOJP_00624 1.2e-157 aatB ET ABC transporter substrate-binding protein
KCOEDOJP_00625 1.5e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCOEDOJP_00626 4e-105 artQ P ABC transporter (Permease
KCOEDOJP_00627 2.5e-58 phnA P Alkylphosphonate utilization operon protein PhnA
KCOEDOJP_00628 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KCOEDOJP_00629 4.5e-166 cpsY K Transcriptional regulator
KCOEDOJP_00630 4.2e-20 L transposase activity
KCOEDOJP_00631 1.6e-118 mur1 NU muramidase
KCOEDOJP_00632 1e-171 yeiH S Membrane
KCOEDOJP_00633 1.1e-250 L Transposase
KCOEDOJP_00634 9.4e-60
KCOEDOJP_00635 4.2e-49 L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
KCOEDOJP_00636 1.5e-24 L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. BELONGS TO THE IS30 FAMILY OF TRANSPOSASE. There are 15 such elements in the chromosome
KCOEDOJP_00637 1.7e-08
KCOEDOJP_00638 3.6e-293 adcA P Belongs to the bacterial solute-binding protein 9 family
KCOEDOJP_00639 4.4e-75 XK27_10720 D peptidase activity
KCOEDOJP_00640 2e-79 hsdM 2.1.1.72 V HsdM N-terminal domain
KCOEDOJP_00641 1.1e-08 mycA 4.2.1.53 S Myosin-crossreactive antigen
KCOEDOJP_00642 1.3e-115 V ABC transporter (Permease
KCOEDOJP_00643 2.8e-115 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KCOEDOJP_00644 9e-98 K Transcriptional regulator, TetR family
KCOEDOJP_00645 3.1e-159 czcD P cation diffusion facilitator family transporter
KCOEDOJP_00646 1.5e-52 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KCOEDOJP_00647 6.7e-144 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KCOEDOJP_00648 6.2e-196 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
KCOEDOJP_00649 6e-08 S Hydrolases of the alpha beta superfamily
KCOEDOJP_00650 7.9e-17 S Alpha/beta hydrolase of unknown function (DUF915)
KCOEDOJP_00651 1.7e-78 S Alpha/beta hydrolase of unknown function (DUF915)
KCOEDOJP_00654 2.6e-143 2.4.2.3 F Phosphorylase superfamily
KCOEDOJP_00655 8.3e-119 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
KCOEDOJP_00656 3.6e-14 yclQ P ABC-type enterochelin transport system, periplasmic component
KCOEDOJP_00657 1.2e-18 yclQ P ABC-type enterochelin transport system, periplasmic component
KCOEDOJP_00658 8.8e-55 dinF V Mate efflux family protein
KCOEDOJP_00660 2.3e-309 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KCOEDOJP_00662 6.4e-54 S TraX protein
KCOEDOJP_00663 1.3e-96 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
KCOEDOJP_00664 1.5e-149 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KCOEDOJP_00665 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KCOEDOJP_00666 4e-184 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCOEDOJP_00667 1.5e-36 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCOEDOJP_00668 1.2e-132 cas6 S CRISPR-associated endoribonuclease Cas6
KCOEDOJP_00669 0.0 csm1 S CRISPR-associated protein Csm1 family
KCOEDOJP_00670 3.6e-42 csm2 L Csm2 Type III-A
KCOEDOJP_00671 1.6e-117 csm3 L RAMP superfamily
KCOEDOJP_00672 5.2e-167 csm4 L CRISPR-associated RAMP protein, Csm4 family
KCOEDOJP_00673 2e-205 csm5 L CRISPR-associated RAMP protein, Csm5 family
KCOEDOJP_00675 9.5e-32 csm6 S Psort location Cytoplasmic, score
KCOEDOJP_00676 2.4e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KCOEDOJP_00677 5.7e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KCOEDOJP_00678 8.1e-48 nylA 3.5.1.4 J Belongs to the amidase family
KCOEDOJP_00679 6.1e-266 dtpT E transporter
KCOEDOJP_00680 1.4e-62 yecS P ABC transporter (Permease
KCOEDOJP_00681 2.3e-20 yecS P amino acid transport
KCOEDOJP_00683 8.1e-114 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
KCOEDOJP_00684 9.8e-35 3.1.3.6, 3.1.4.16 F nucleotide catabolic process
KCOEDOJP_00685 1.6e-103 yfiF3 K sequence-specific DNA binding
KCOEDOJP_00686 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCOEDOJP_00687 2.5e-33 ykzG S Belongs to the UPF0356 family
KCOEDOJP_00688 1.4e-119 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
KCOEDOJP_00689 4.8e-73 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KCOEDOJP_00690 1.9e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KCOEDOJP_00691 8.5e-117 azlC E AzlC protein
KCOEDOJP_00692 8.8e-48 azlD E branched-chain amino acid
KCOEDOJP_00693 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KCOEDOJP_00694 1.3e-111 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCOEDOJP_00695 1e-159 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KCOEDOJP_00696 2.3e-13 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KCOEDOJP_00697 6.7e-93 cvpA S toxin biosynthetic process
KCOEDOJP_00698 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KCOEDOJP_00699 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KCOEDOJP_00704 2.5e-230 mutY L A G-specific adenine glycosylase
KCOEDOJP_00705 2.8e-41 XK27_05745
KCOEDOJP_00706 3.9e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
KCOEDOJP_00707 2.7e-91 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KCOEDOJP_00708 9.7e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KCOEDOJP_00710 3.1e-124 XK27_01040 S Pfam PF06570
KCOEDOJP_00711 5e-168 corA P COG0598 Mg2 and Co2 transporters
KCOEDOJP_00712 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KCOEDOJP_00715 1e-58 V 'abc transporter, ATP-binding protein
KCOEDOJP_00716 8e-44 V 'abc transporter, ATP-binding protein
KCOEDOJP_00718 5e-193 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
KCOEDOJP_00719 3.7e-84 comEB 3.5.4.12 F ComE operon protein 2
KCOEDOJP_00720 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KCOEDOJP_00721 3.4e-62 yqhY S protein conserved in bacteria
KCOEDOJP_00722 3.6e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KCOEDOJP_00724 8e-138 mreC M Involved in formation and maintenance of cell shape
KCOEDOJP_00725 8.2e-88 mreD M Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KCOEDOJP_00726 5.1e-94 usp 3.5.1.28 CBM50 S CHAP domain
KCOEDOJP_00727 4.3e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KCOEDOJP_00728 5.9e-219 araT 2.6.1.1 E Aminotransferase
KCOEDOJP_00729 1.6e-143 recO L Involved in DNA repair and RecF pathway recombination
KCOEDOJP_00730 8.8e-131 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KCOEDOJP_00731 2.5e-43 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KCOEDOJP_00732 4.2e-34 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCOEDOJP_00733 1.2e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KCOEDOJP_00734 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KCOEDOJP_00735 8.6e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KCOEDOJP_00736 1.8e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KCOEDOJP_00737 1.4e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KCOEDOJP_00738 8.1e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KCOEDOJP_00739 3.1e-75 L transposase activity
KCOEDOJP_00740 1.4e-48 L transposition
KCOEDOJP_00741 1.4e-33 L Integrase core domain protein
KCOEDOJP_00742 6.4e-159 S CHAP domain
KCOEDOJP_00743 6.5e-240 purD 6.3.4.13 F Belongs to the GARS family
KCOEDOJP_00744 4.9e-76 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KCOEDOJP_00745 1.6e-202 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KCOEDOJP_00746 2e-140 1.1.1.169 H Ketopantoate reductase
KCOEDOJP_00747 8.7e-248 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KCOEDOJP_00748 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
KCOEDOJP_00749 1.2e-09 L Transposase
KCOEDOJP_00750 2.6e-214 ugd 1.1.1.22 M UDP binding domain
KCOEDOJP_00751 2.7e-121 nodC 2.4.1.212 GT2 M Chitin synthase
KCOEDOJP_00752 5.8e-69 nodC 2.4.1.212 GT2 M Glycosyl transferase family 21
KCOEDOJP_00753 4.3e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KCOEDOJP_00754 6.3e-193 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KCOEDOJP_00755 5.4e-153 yvjA S membrane
KCOEDOJP_00756 5.7e-305 ybiT S abc transporter atp-binding protein
KCOEDOJP_00757 0.0 XK27_10405 S Bacterial membrane protein YfhO
KCOEDOJP_00761 6.2e-120 yoaK S Psort location CytoplasmicMembrane, score
KCOEDOJP_00762 6.2e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KCOEDOJP_00763 8.7e-197 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
KCOEDOJP_00764 8.5e-134 parB K Belongs to the ParB family
KCOEDOJP_00765 1.3e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KCOEDOJP_00766 8.2e-202 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KCOEDOJP_00767 1.1e-29 yyzM S Protein conserved in bacteria
KCOEDOJP_00768 8.6e-204 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KCOEDOJP_00769 1.4e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KCOEDOJP_00770 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KCOEDOJP_00771 1.7e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KCOEDOJP_00772 2.7e-61 divIC D Septum formation initiator
KCOEDOJP_00774 1.3e-240 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
KCOEDOJP_00775 5e-240 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KCOEDOJP_00776 3.4e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KCOEDOJP_00777 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KCOEDOJP_00778 8.7e-84 L Transposase
KCOEDOJP_00779 4e-50 L Transposase
KCOEDOJP_00780 1.6e-106 pvaA M lytic transglycosylase activity
KCOEDOJP_00781 1.2e-177 ndpA S 37-kD nucleoid-associated bacterial protein
KCOEDOJP_00782 4e-234 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KCOEDOJP_00783 2.8e-108 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KCOEDOJP_00784 1e-153 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KCOEDOJP_00785 2.6e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KCOEDOJP_00786 3.5e-111 tdk 2.7.1.21 F thymidine kinase
KCOEDOJP_00787 6.7e-187 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KCOEDOJP_00788 2.6e-154 gst O Glutathione S-transferase
KCOEDOJP_00789 7.6e-177 nrnA 3.1.13.3, 3.1.3.7 S domain protein
KCOEDOJP_00790 1.2e-174 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KCOEDOJP_00791 2e-45 rpmE2 J 50S ribosomal protein L31
KCOEDOJP_00792 7.9e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
KCOEDOJP_00793 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KCOEDOJP_00794 1.8e-135 divIVA D Cell division protein DivIVA
KCOEDOJP_00795 1.6e-143 ylmH T S4 RNA-binding domain
KCOEDOJP_00796 4.4e-34 yggT D integral membrane protein
KCOEDOJP_00797 6.8e-96 sepF D cell septum assembly
KCOEDOJP_00798 2.3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KCOEDOJP_00799 5.4e-237 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KCOEDOJP_00800 8e-252 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KCOEDOJP_00801 5.7e-171 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KCOEDOJP_00802 1e-201 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KCOEDOJP_00803 1.6e-252 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KCOEDOJP_00805 0.0 typA T GTP-binding protein TypA
KCOEDOJP_00806 3e-176 glk 2.7.1.2 G Glucokinase
KCOEDOJP_00807 1.9e-27 yqgQ S protein conserved in bacteria
KCOEDOJP_00808 8.9e-80 perR P Belongs to the Fur family
KCOEDOJP_00809 3.2e-92 dps P Belongs to the Dps family
KCOEDOJP_00810 1.5e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KCOEDOJP_00811 1.3e-185 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
KCOEDOJP_00812 8.5e-113 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
KCOEDOJP_00813 2.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
KCOEDOJP_00814 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KCOEDOJP_00815 5.3e-55 S Domain of unknown function (DUF4430)
KCOEDOJP_00816 2.1e-74 S Psort location CytoplasmicMembrane, score
KCOEDOJP_00817 1.2e-131 htpX O Belongs to the peptidase M48B family
KCOEDOJP_00818 6.5e-91 lemA S LemA family
KCOEDOJP_00819 9.2e-173 spd F DNA RNA non-specific endonuclease
KCOEDOJP_00820 2.6e-70
KCOEDOJP_00822 1.2e-139 3.1.21.3 V type I restriction modification DNA specificity domain
KCOEDOJP_00823 6.2e-288 hsdM 2.1.1.72 V N-6 DNA Methylase
KCOEDOJP_00824 0.0 hsdR 3.1.21.3 V Type I restriction enzyme R protein N terminus (HSDR_N)
KCOEDOJP_00825 2.4e-40 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCOEDOJP_00826 1.2e-21 MA20_36090 S Protein of unknown function (DUF2974)
KCOEDOJP_00827 7.2e-23 MA20_36090 S Protein of unknown function (DUF2974)
KCOEDOJP_00828 5.2e-113 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KCOEDOJP_00829 2.7e-27 P Hemerythrin HHE cation binding domain protein
KCOEDOJP_00830 4.5e-145 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
KCOEDOJP_00831 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KCOEDOJP_00832 3.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
KCOEDOJP_00833 2.3e-175 S hydrolase
KCOEDOJP_00834 3.4e-16
KCOEDOJP_00835 1.6e-62 M LysM domain
KCOEDOJP_00836 3.7e-52 M LysM domain
KCOEDOJP_00837 1.9e-15 M LysM domain
KCOEDOJP_00838 7.5e-288 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KCOEDOJP_00839 4.4e-24 S Protein of unknown function (DUF1643)
KCOEDOJP_00840 3.7e-161 haeIIIM 2.1.1.37 L C-5 cytosine-specific DNA methylase
KCOEDOJP_00841 6.2e-64
KCOEDOJP_00842 7.8e-19 pvuIIC K Helix-turn-helix domain
KCOEDOJP_00846 6.3e-38
KCOEDOJP_00847 2.1e-39
KCOEDOJP_00848 6.2e-99 L helicase
KCOEDOJP_00849 3.1e-68 nudG 3.6.1.55, 3.6.1.65 L Belongs to the Nudix hydrolase family
KCOEDOJP_00850 3.3e-12
KCOEDOJP_00851 3e-235 mntH P H( )-stimulated, divalent metal cation uptake system
KCOEDOJP_00852 1.1e-33 XK27_12190 S protein conserved in bacteria
KCOEDOJP_00854 3.5e-86 bioY S biotin synthase
KCOEDOJP_00855 3.4e-252 yegQ O Peptidase U32
KCOEDOJP_00856 4.4e-177 yegQ O Peptidase U32
KCOEDOJP_00858 5.5e-69 ytxH S General stress protein
KCOEDOJP_00860 4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KCOEDOJP_00861 5.8e-169 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KCOEDOJP_00862 9.9e-42 pspC KT PspC domain
KCOEDOJP_00863 0.0 yhgF K Transcriptional accessory protein
KCOEDOJP_00865 3.5e-155 XK27_03015 S permease
KCOEDOJP_00866 1.3e-148 ycgQ S TIGR03943 family
KCOEDOJP_00867 4.2e-192 S CRISPR-associated protein Csn2 subfamily St
KCOEDOJP_00868 1.8e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCOEDOJP_00869 1.1e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KCOEDOJP_00870 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KCOEDOJP_00871 1.1e-94
KCOEDOJP_00872 6.3e-33 estA E GDSL-like Lipase/Acylhydrolase
KCOEDOJP_00873 3e-49 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KCOEDOJP_00874 1e-31 K Cro/C1-type HTH DNA-binding domain
KCOEDOJP_00875 3.2e-46
KCOEDOJP_00876 1.2e-19
KCOEDOJP_00877 6.5e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCOEDOJP_00878 4.5e-97 mip S hydroperoxide reductase activity
KCOEDOJP_00879 4.1e-203 I acyl-CoA dehydrogenase
KCOEDOJP_00880 3.5e-150 ydiA P C4-dicarboxylate transporter malic acid transport protein
KCOEDOJP_00881 1.1e-251 msrR K Transcriptional regulator
KCOEDOJP_00882 5.1e-153 pheA 4.2.1.51 E Prephenate dehydratase
KCOEDOJP_00883 1.7e-87 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KCOEDOJP_00884 4.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KCOEDOJP_00885 3.9e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KCOEDOJP_00886 3.2e-53 yheA S Belongs to the UPF0342 family
KCOEDOJP_00887 2.2e-207 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KCOEDOJP_00888 4.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KCOEDOJP_00889 3.5e-202 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KCOEDOJP_00890 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KCOEDOJP_00891 8.6e-122 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KCOEDOJP_00892 2e-219 ywbD 2.1.1.191 J Methyltransferase
KCOEDOJP_00893 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KCOEDOJP_00895 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KCOEDOJP_00896 7.4e-77 yueI S Protein of unknown function (DUF1694)
KCOEDOJP_00897 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KCOEDOJP_00898 6.6e-101 yyaQ V Protein conserved in bacteria
KCOEDOJP_00899 2.8e-28 yyaQ S YjbR
KCOEDOJP_00900 4.4e-183 ccpA K Catabolite control protein A
KCOEDOJP_00901 4.2e-211 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
KCOEDOJP_00902 1.7e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
KCOEDOJP_00903 5.3e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCOEDOJP_00904 1.1e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KCOEDOJP_00905 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KCOEDOJP_00906 2e-33 secG U Preprotein translocase subunit SecG
KCOEDOJP_00907 9.5e-74 mdtG EGP Major facilitator Superfamily
KCOEDOJP_00908 4e-128 mdtG EGP Major facilitator Superfamily
KCOEDOJP_00909 1.3e-105 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KCOEDOJP_00910 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KCOEDOJP_00911 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KCOEDOJP_00912 8.3e-64 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KCOEDOJP_00913 5.9e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KCOEDOJP_00914 6.8e-53 licT K transcriptional antiterminator
KCOEDOJP_00915 5.4e-43 licT K transcriptional antiterminator
KCOEDOJP_00916 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KCOEDOJP_00917 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
KCOEDOJP_00918 5.4e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KCOEDOJP_00919 3.7e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KCOEDOJP_00920 7.5e-23 I Alpha/beta hydrolase family
KCOEDOJP_00921 2.5e-33 yugF I carboxylic ester hydrolase activity
KCOEDOJP_00922 2.2e-45 K sequence-specific DNA binding
KCOEDOJP_00923 2.4e-104 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCOEDOJP_00924 1.5e-07
KCOEDOJP_00925 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KCOEDOJP_00926 1.1e-78 feoA P FeoA domain protein
KCOEDOJP_00927 2.2e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCOEDOJP_00928 7.5e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
KCOEDOJP_00929 1.3e-34 ykuJ S protein conserved in bacteria
KCOEDOJP_00930 1.3e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KCOEDOJP_00931 0.0 clpE O Belongs to the ClpA ClpB family
KCOEDOJP_00932 5.7e-85 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KCOEDOJP_00933 2.4e-47 XK27_09445 S Domain of unknown function (DUF1827)
KCOEDOJP_00934 9.7e-66 S oxidoreductase
KCOEDOJP_00935 9.3e-59 S oxidoreductase
KCOEDOJP_00936 1.6e-08 S oxidoreductase
KCOEDOJP_00937 1.3e-232 murN 2.3.2.10, 2.3.2.16 V FemAB family
KCOEDOJP_00938 1e-69 M Pfam SNARE associated Golgi protein
KCOEDOJP_00939 1e-100 S Domain of Unknown Function with PDB structure (DUF3862)
KCOEDOJP_00942 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
KCOEDOJP_00945 4.8e-16 S Protein of unknown function (DUF2969)
KCOEDOJP_00946 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
KCOEDOJP_00947 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCOEDOJP_00948 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KCOEDOJP_00949 2.3e-100 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KCOEDOJP_00950 4.9e-15 L Helix-hairpin-helix DNA-binding motif class 1
KCOEDOJP_00951 1.4e-29 S Domain of unknown function (DUF1912)
KCOEDOJP_00952 1.4e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
KCOEDOJP_00953 9.2e-248 mmuP E amino acid
KCOEDOJP_00954 1.5e-109 engB D Necessary for normal cell division and for the maintenance of normal septation
KCOEDOJP_00955 2.2e-224 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KCOEDOJP_00956 9.7e-22
KCOEDOJP_00957 2.2e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KCOEDOJP_00958 6.5e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KCOEDOJP_00959 1.7e-218 mvaS 2.3.3.10 I synthase
KCOEDOJP_00960 2.7e-233 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KCOEDOJP_00961 1e-25 K hmm pf08876
KCOEDOJP_00962 1.5e-118 yqfA K protein, Hemolysin III
KCOEDOJP_00963 3.6e-22 S Protein of unknown function (DUF3114)
KCOEDOJP_00964 4e-164 S Protein of unknown function (DUF3114)
KCOEDOJP_00965 1.4e-69 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KCOEDOJP_00966 7.1e-48 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KCOEDOJP_00967 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KCOEDOJP_00968 2.7e-49 XK27_13030
KCOEDOJP_00969 4.4e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KCOEDOJP_00970 1.1e-192 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
KCOEDOJP_00972 2.1e-50 U protein secretion
KCOEDOJP_00973 3.5e-07 U protein secretion
KCOEDOJP_00975 4.5e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KCOEDOJP_00976 2.1e-07
KCOEDOJP_00977 1e-96 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
KCOEDOJP_00978 5.1e-254 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KCOEDOJP_00979 8.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KCOEDOJP_00980 4.6e-180 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I GHMP kinases N terminal domain
KCOEDOJP_00981 6e-174 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KCOEDOJP_00982 7.4e-142 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KCOEDOJP_00983 4.6e-105 GBS0088 J protein conserved in bacteria
KCOEDOJP_00984 8e-249 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCOEDOJP_00985 1.7e-46 ald 1.4.1.1 C Belongs to the AlaDH PNT family
KCOEDOJP_00986 3.4e-17 ald 1.4.1.1 E alanine dehydrogenase activity
KCOEDOJP_00987 2.6e-219 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KCOEDOJP_00988 7.4e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCOEDOJP_00989 2.5e-113 S VIT family
KCOEDOJP_00990 1.4e-144 deoD_1 2.4.2.3 F Phosphorylase superfamily
KCOEDOJP_00991 7.3e-22
KCOEDOJP_00992 2.3e-27 XK27_00085 K Transcriptional
KCOEDOJP_00993 1.5e-196 yceA S Belongs to the UPF0176 family
KCOEDOJP_00994 5.4e-122 sagI S ABC-2 type transporter
KCOEDOJP_00995 2.8e-168 V ABC transporter
KCOEDOJP_00996 1.3e-218 2.7.7.73, 2.7.7.80 H Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KCOEDOJP_00997 2.5e-132 rr02 KT response regulator
KCOEDOJP_00998 3.3e-215 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
KCOEDOJP_00999 3.7e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KCOEDOJP_01000 2.8e-196 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KCOEDOJP_01001 0.0 lmrA V abc transporter atp-binding protein
KCOEDOJP_01002 0.0 mdlB V abc transporter atp-binding protein
KCOEDOJP_01004 2.2e-244 cps1C S Polysaccharide biosynthesis protein
KCOEDOJP_01005 4.2e-90 2.7.8.12 GT2 M Glycosyltransferase like family 2
KCOEDOJP_01006 4.4e-121 L Transposase DDE domain
KCOEDOJP_01007 8.8e-91 2.7.8.12 GT2 S Glycosyltransferase like family 2
KCOEDOJP_01008 1.8e-139 L Integrase core domain
KCOEDOJP_01009 6.5e-15 L Transposase
KCOEDOJP_01010 6e-123 tnp L DDE domain
KCOEDOJP_01011 9e-09 rgpAc GT4 M group 1 family protein
KCOEDOJP_01012 7.5e-258 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KCOEDOJP_01013 1.1e-117 cpsD D COG0489 ATPases involved in chromosome partitioning
KCOEDOJP_01014 4.7e-107 cps4C M biosynthesis protein
KCOEDOJP_01015 3.9e-136 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
KCOEDOJP_01016 1.6e-253 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
KCOEDOJP_01017 6.9e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
KCOEDOJP_01018 5.8e-110 yfeJ 6.3.5.2 F glutamine amidotransferase
KCOEDOJP_01019 7.3e-41 clcA_2 P chloride
KCOEDOJP_01020 3.8e-42 clcA_2 P chloride channel
KCOEDOJP_01021 4.4e-149 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KCOEDOJP_01022 8.1e-41 S Protein of unknown function (DUF1697)
KCOEDOJP_01023 2.9e-237 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KCOEDOJP_01024 5e-122 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KCOEDOJP_01026 6.1e-22 V Glucan-binding protein C
KCOEDOJP_01027 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
KCOEDOJP_01028 1.5e-274 pepV 3.5.1.18 E Dipeptidase
KCOEDOJP_01029 6.4e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KCOEDOJP_01030 5.3e-86 XK27_03610 K Gnat family
KCOEDOJP_01033 2.1e-166 ppaC 3.6.1.1 C inorganic pyrophosphatase
KCOEDOJP_01034 6.4e-108 S Domain of unknown function (DUF1803)
KCOEDOJP_01035 1.3e-101 ygaC J Belongs to the UPF0374 family
KCOEDOJP_01036 7.3e-133 recX 2.4.1.337 GT4 S Regulatory protein RecX
KCOEDOJP_01037 1.4e-259 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KCOEDOJP_01038 8e-193 asnA 6.3.1.1 E aspartate--ammonia ligase
KCOEDOJP_01039 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
KCOEDOJP_01040 1.9e-115 S Haloacid dehalogenase-like hydrolase
KCOEDOJP_01041 2.4e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
KCOEDOJP_01042 1.5e-71 marR K Transcriptional regulator, MarR family
KCOEDOJP_01043 2.3e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KCOEDOJP_01044 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KCOEDOJP_01045 2.6e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
KCOEDOJP_01046 8.5e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KCOEDOJP_01047 1.6e-126 IQ reductase
KCOEDOJP_01048 1.5e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KCOEDOJP_01049 2e-56 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KCOEDOJP_01050 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KCOEDOJP_01051 2.8e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KCOEDOJP_01052 1.3e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KCOEDOJP_01053 6.7e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KCOEDOJP_01054 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KCOEDOJP_01055 8.1e-203 rny D Endoribonuclease that initiates mRNA decay
KCOEDOJP_01056 5.2e-84 L Transposase
KCOEDOJP_01057 5.1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KCOEDOJP_01058 2e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KCOEDOJP_01059 7.2e-64 XK27_08585 S Psort location CytoplasmicMembrane, score
KCOEDOJP_01060 6.4e-54 fnt P Formate nitrite transporter
KCOEDOJP_01061 1.9e-07 fnt P Formate nitrite transporter
KCOEDOJP_01062 2.3e-141 XK27_09615 C reductase
KCOEDOJP_01063 9e-62 XK27_09615 C reductase
KCOEDOJP_01064 4.3e-77 XK27_09620 S reductase
KCOEDOJP_01065 1.4e-19 XK27_09620 S FMN reductase (NADPH) activity
KCOEDOJP_01066 1.1e-80 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KCOEDOJP_01067 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KCOEDOJP_01068 8.1e-12 WQ51_05710 S Mitochondrial biogenesis AIM24
KCOEDOJP_01069 1.4e-36 WQ51_05710 S Mitochondrial biogenesis AIM24
KCOEDOJP_01070 1.1e-25 WQ51_05710 S Mitochondrial biogenesis AIM24
KCOEDOJP_01071 2e-88 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KCOEDOJP_01072 9.2e-51 S Protein of unknown function (DUF3397)
KCOEDOJP_01073 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KCOEDOJP_01074 2.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KCOEDOJP_01075 4.2e-74 amiA E transmembrane transport
KCOEDOJP_01076 6.6e-63 amiA E transmembrane transport
KCOEDOJP_01077 2e-20 amiA E ABC transporter, substrate-binding protein, family 5
KCOEDOJP_01078 2.1e-282 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KCOEDOJP_01079 1.3e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KCOEDOJP_01080 5.4e-264 argH 4.3.2.1 E Argininosuccinate lyase
KCOEDOJP_01081 5.9e-55 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KCOEDOJP_01082 7.5e-141 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCOEDOJP_01083 2e-186 jag S RNA-binding protein
KCOEDOJP_01084 1e-13 rpmH J Ribosomal protein L34
KCOEDOJP_01085 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KCOEDOJP_01086 3.5e-35 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KCOEDOJP_01087 2.4e-275 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KCOEDOJP_01088 6.6e-61 EGP Major facilitator Superfamily
KCOEDOJP_01089 3.9e-136 speB 3.5.3.11 E hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
KCOEDOJP_01090 1.3e-212 pqqE C radical SAM domain protein
KCOEDOJP_01093 5.2e-156 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
KCOEDOJP_01094 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KCOEDOJP_01095 1.9e-100 IQ Acetoin reductase
KCOEDOJP_01096 1e-47 pspE P Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCOEDOJP_01097 1.7e-75 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KCOEDOJP_01098 3.8e-153 XK27_05470 E Methionine synthase
KCOEDOJP_01099 6.6e-259 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KCOEDOJP_01100 9e-251 T PhoQ Sensor
KCOEDOJP_01101 2.2e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCOEDOJP_01102 3.6e-154 S TraX protein
KCOEDOJP_01103 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KCOEDOJP_01104 9e-29 dprA LU DNA protecting protein DprA
KCOEDOJP_01105 1.5e-97 ybhL S Belongs to the BI1 family
KCOEDOJP_01106 4.7e-93 XK27_09705 6.1.1.14 S HD superfamily hydrolase
KCOEDOJP_01107 6.4e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KCOEDOJP_01108 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KCOEDOJP_01109 2.9e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KCOEDOJP_01110 2.5e-83 L Integrase core domain protein
KCOEDOJP_01111 1.6e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KCOEDOJP_01112 0.0 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KCOEDOJP_01113 3.5e-82 XK27_09675 K -acetyltransferase
KCOEDOJP_01114 2.6e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KCOEDOJP_01115 2.5e-23
KCOEDOJP_01116 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
KCOEDOJP_01117 7.2e-296 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
KCOEDOJP_01118 1.5e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KCOEDOJP_01119 4.3e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KCOEDOJP_01120 4.9e-93 ypsA S Belongs to the UPF0398 family
KCOEDOJP_01121 2.4e-107 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KCOEDOJP_01122 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCOEDOJP_01123 3.3e-62 rplQ J ribosomal protein l17
KCOEDOJP_01124 4.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KCOEDOJP_01125 9.6e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KCOEDOJP_01126 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KCOEDOJP_01127 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KCOEDOJP_01128 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KCOEDOJP_01129 9.2e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KCOEDOJP_01130 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KCOEDOJP_01131 4.4e-58 rplO J binds to the 23S rRNA
KCOEDOJP_01132 2.5e-23 rpmD J ribosomal protein l30
KCOEDOJP_01133 1.7e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KCOEDOJP_01134 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KCOEDOJP_01135 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KCOEDOJP_01136 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KCOEDOJP_01137 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KCOEDOJP_01138 1.2e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KCOEDOJP_01139 5.3e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KCOEDOJP_01140 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KCOEDOJP_01141 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KCOEDOJP_01142 2.7e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
KCOEDOJP_01143 1e-69 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KCOEDOJP_01144 9.8e-115 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KCOEDOJP_01145 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KCOEDOJP_01146 4.9e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KCOEDOJP_01147 2.6e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KCOEDOJP_01148 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KCOEDOJP_01149 7.4e-104 rplD J Forms part of the polypeptide exit tunnel
KCOEDOJP_01150 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KCOEDOJP_01151 1.3e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
KCOEDOJP_01152 7.8e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KCOEDOJP_01153 0.0 XK27_09800 I Acyltransferase
KCOEDOJP_01154 1.7e-35 XK27_09805 S MORN repeat protein
KCOEDOJP_01155 1e-80 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KCOEDOJP_01156 4.4e-53 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCOEDOJP_01157 7e-127 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KCOEDOJP_01158 0.0 clpC O Belongs to the ClpA ClpB family
KCOEDOJP_01159 6.2e-76 ctsR K Belongs to the CtsR family
KCOEDOJP_01160 1.1e-83 S Putative small multi-drug export protein
KCOEDOJP_01161 5.1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KCOEDOJP_01162 1.2e-135 rpsB J Belongs to the universal ribosomal protein uS2 family
KCOEDOJP_01164 5.4e-09 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KCOEDOJP_01165 1.8e-150 yocD 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KCOEDOJP_01167 1.3e-42 L transposition
KCOEDOJP_01168 2e-88 L Integrase core domain protein
KCOEDOJP_01169 1.6e-94 S reductase
KCOEDOJP_01170 2e-42 badR K DNA-binding transcription factor activity
KCOEDOJP_01171 5.5e-36 XK27_02060 S Transglycosylase associated protein
KCOEDOJP_01172 2.8e-235 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KCOEDOJP_01173 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCOEDOJP_01178 1.9e-07
KCOEDOJP_01179 5.1e-259 pepC 3.4.22.40 E aminopeptidase
KCOEDOJP_01180 1.9e-77 yhaI L Membrane
KCOEDOJP_01181 2.1e-151 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KCOEDOJP_01182 2.4e-278 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KCOEDOJP_01183 6.2e-137 S COG1073 Hydrolases of the alpha beta superfamily
KCOEDOJP_01184 2e-24 S COG1073 Hydrolases of the alpha beta superfamily
KCOEDOJP_01185 7.6e-41 K transcriptional
KCOEDOJP_01186 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KCOEDOJP_01187 3.9e-21 glcR K transcriptional regulator (DeoR family)
KCOEDOJP_01188 4.4e-77 glcR K transcriptional regulator (DeoR family)
KCOEDOJP_01189 1.9e-31 cof Q phosphatase activity
KCOEDOJP_01190 1.3e-45 cof Q phosphatase activity
KCOEDOJP_01191 3.7e-73 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
KCOEDOJP_01192 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
KCOEDOJP_01193 1.6e-24 secE U Belongs to the SecE SEC61-gamma family
KCOEDOJP_01194 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KCOEDOJP_01195 4e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCOEDOJP_01196 7.6e-55 S TM2 domain
KCOEDOJP_01197 4.6e-37
KCOEDOJP_01200 2.2e-54 bta 1.8.1.8 CO cell redox homeostasis
KCOEDOJP_01201 2e-09 L thioesterase
KCOEDOJP_01202 2.5e-141 S Macro domain protein
KCOEDOJP_01203 4.8e-51 trxA O Belongs to the thioredoxin family
KCOEDOJP_01204 1.5e-74 yccU S CoA-binding protein
KCOEDOJP_01205 1.6e-143 tatD L Hydrolase, tatd
KCOEDOJP_01206 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KCOEDOJP_01207 5.2e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KCOEDOJP_01209 1.3e-162 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KCOEDOJP_01210 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KCOEDOJP_01211 9.2e-118 thiN 2.7.6.2 H thiamine pyrophosphokinase
KCOEDOJP_01212 6.9e-173 rmuC S RmuC domain protein
KCOEDOJP_01213 3.6e-179 cbf S 3'-5' exoribonuclease yhaM
KCOEDOJP_01214 2.4e-142 purR 2.4.2.7 F operon repressor
KCOEDOJP_01215 5.1e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KCOEDOJP_01216 4.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KCOEDOJP_01217 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KCOEDOJP_01218 4.3e-186 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KCOEDOJP_01219 1.1e-86 L Integrase core domain protein
KCOEDOJP_01220 2.3e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
KCOEDOJP_01221 4.7e-205 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KCOEDOJP_01222 6.5e-232 cinA 3.5.1.42 S Belongs to the CinA family
KCOEDOJP_01223 1.9e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
KCOEDOJP_01224 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KCOEDOJP_01226 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KCOEDOJP_01228 2.1e-68 K LytTr DNA-binding domain
KCOEDOJP_01229 1.5e-77 S Protein of unknown function (DUF3021)
KCOEDOJP_01230 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KCOEDOJP_01231 1e-57 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KCOEDOJP_01232 8.2e-70 argR K Regulates arginine biosynthesis genes
KCOEDOJP_01234 3.8e-57 T Toxic component of a toxin-antitoxin (TA) module
KCOEDOJP_01237 3.5e-28 3.4.13.21 I Protein conserved in bacteria
KCOEDOJP_01238 9e-89 FNV0100 F Belongs to the Nudix hydrolase family
KCOEDOJP_01239 5.6e-114 fruR K transcriptional
KCOEDOJP_01240 5.5e-164 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
KCOEDOJP_01241 3.9e-54 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
KCOEDOJP_01242 5.9e-50 fruA 2.7.1.202 GT PTS system, Lactose/Cellobiose specific IIB subunit
KCOEDOJP_01243 4.9e-208 fruA 2.7.1.202 G phosphotransferase system
KCOEDOJP_01244 2.7e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KCOEDOJP_01245 8.1e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KCOEDOJP_01247 8e-213 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
KCOEDOJP_01248 3.8e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KCOEDOJP_01249 4.9e-295 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KCOEDOJP_01250 2.1e-257 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
KCOEDOJP_01251 6.4e-29 2.3.1.128 K acetyltransferase
KCOEDOJP_01252 1.3e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
KCOEDOJP_01253 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KCOEDOJP_01254 3e-127 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCOEDOJP_01255 2.6e-64 WQ51_03320 S cog cog4835
KCOEDOJP_01256 6.4e-61 XK27_08360 S EDD domain protein, DegV family
KCOEDOJP_01257 3.6e-74 XK27_08360 S EDD domain protein, DegV family
KCOEDOJP_01258 3e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KCOEDOJP_01259 1.9e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KCOEDOJP_01260 0.0 yfmR S abc transporter atp-binding protein
KCOEDOJP_01261 8.9e-23 U response to pH
KCOEDOJP_01262 1.1e-141 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
KCOEDOJP_01263 1.7e-212 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
KCOEDOJP_01264 1.8e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KCOEDOJP_01265 3.3e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KCOEDOJP_01266 1.9e-77 K DNA-binding transcription factor activity
KCOEDOJP_01267 0.0 lmrA1 V abc transporter atp-binding protein
KCOEDOJP_01268 0.0 lmrA2 V abc transporter atp-binding protein
KCOEDOJP_01269 1.6e-44 K Acetyltransferase (GNAT) family
KCOEDOJP_01270 3e-117 sptS 2.7.13.3 T Histidine kinase
KCOEDOJP_01271 3.2e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KCOEDOJP_01272 1.3e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KCOEDOJP_01273 1.7e-159 cvfB S Protein conserved in bacteria
KCOEDOJP_01274 7.4e-35 yozE S Belongs to the UPF0346 family
KCOEDOJP_01275 3.3e-117 sip M LysM domain protein
KCOEDOJP_01276 8e-191 phoH T phosphate starvation-inducible protein PhoH
KCOEDOJP_01280 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KCOEDOJP_01281 1.2e-166 K transcriptional regulator (lysR family)
KCOEDOJP_01282 1.4e-186 coiA 3.6.4.12 S Competence protein
KCOEDOJP_01283 0.0 pepF E oligoendopeptidase F
KCOEDOJP_01284 5.4e-127 yrrM 2.1.1.104 S O-Methyltransferase
KCOEDOJP_01285 1.3e-167 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
KCOEDOJP_01286 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KCOEDOJP_01287 7.9e-24 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCOEDOJP_01288 6.9e-179 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCOEDOJP_01289 3.9e-120 3.4.17.14, 3.5.1.28 NU amidase activity
KCOEDOJP_01290 4.9e-145 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KCOEDOJP_01291 1.7e-226 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
KCOEDOJP_01292 1.4e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KCOEDOJP_01293 1.5e-222 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KCOEDOJP_01294 5.1e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KCOEDOJP_01295 1.6e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KCOEDOJP_01296 5.9e-131 yxkH G deacetylase
KCOEDOJP_01297 5.2e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
KCOEDOJP_01298 1.7e-151 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KCOEDOJP_01299 1e-151 rarD S Transporter
KCOEDOJP_01300 4.4e-16 T peptidase
KCOEDOJP_01301 8.9e-14 coiA 3.6.4.12 S Competence protein
KCOEDOJP_01302 5.7e-106 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KCOEDOJP_01303 5.3e-74 2.3.1.128, 5.2.1.8 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KCOEDOJP_01304 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KCOEDOJP_01305 3.2e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCOEDOJP_01306 1.6e-123 atpB C it plays a direct role in the translocation of protons across the membrane
KCOEDOJP_01307 2.3e-76 atpF C ATP synthase F(0) sector subunit b
KCOEDOJP_01308 1e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KCOEDOJP_01309 3.8e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KCOEDOJP_01310 2.5e-158 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KCOEDOJP_01311 2.7e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KCOEDOJP_01312 2e-66 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KCOEDOJP_01313 1.4e-229 ftsW D Belongs to the SEDS family
KCOEDOJP_01314 3.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KCOEDOJP_01315 3.4e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KCOEDOJP_01316 1.7e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KCOEDOJP_01317 6.4e-162 holB 2.7.7.7 L dna polymerase iii
KCOEDOJP_01318 3e-124 yaaT S stage 0 sporulation protein
KCOEDOJP_01319 9.5e-55 yabA L Involved in initiation control of chromosome replication
KCOEDOJP_01320 2.7e-160 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KCOEDOJP_01321 4.9e-232 amt P Ammonium Transporter
KCOEDOJP_01322 1.1e-53 glnB K Belongs to the P(II) protein family
KCOEDOJP_01323 4.9e-106 mur1 NU mannosyl-glycoprotein
KCOEDOJP_01324 2.2e-148 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
KCOEDOJP_01325 2.9e-68 nptA P sodium-dependent phosphate transmembrane transporter activity
KCOEDOJP_01326 3.6e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KCOEDOJP_01327 1.8e-53
KCOEDOJP_01328 7.5e-26
KCOEDOJP_01329 3.9e-60
KCOEDOJP_01330 6.1e-63 S membrane
KCOEDOJP_01331 4.8e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KCOEDOJP_01332 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KCOEDOJP_01333 4.5e-39 ynzC S UPF0291 protein
KCOEDOJP_01334 1.8e-254 cycA E permease
KCOEDOJP_01335 1.1e-09 uvrX 2.7.7.7 L ImpB mucB samB family
KCOEDOJP_01336 9.1e-23 pts33BCA G pts system
KCOEDOJP_01337 3.3e-37 pts33BCA G pts system
KCOEDOJP_01338 9e-96 pts33BCA G pts system
KCOEDOJP_01339 9.7e-77 2.7.1.199, 2.7.1.211 G PTS glucose transporter subunit IIA
KCOEDOJP_01340 3.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KCOEDOJP_01345 1.4e-167 fhuR K transcriptional regulator (lysR family)
KCOEDOJP_01346 1.5e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KCOEDOJP_01347 1.9e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KCOEDOJP_01348 3.7e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KCOEDOJP_01349 4.9e-227 pyrP F uracil Permease
KCOEDOJP_01350 1e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KCOEDOJP_01351 1.1e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
KCOEDOJP_01352 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
KCOEDOJP_01353 7.1e-133 2.1.1.223 S Putative SAM-dependent methyltransferase
KCOEDOJP_01354 4.4e-30 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KCOEDOJP_01355 1.2e-46 V efflux transmembrane transporter activity
KCOEDOJP_01356 3.1e-31 V efflux transmembrane transporter activity
KCOEDOJP_01357 8.2e-28 ytrF V efflux transmembrane transporter activity
KCOEDOJP_01358 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KCOEDOJP_01359 3.9e-52 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KCOEDOJP_01360 2.1e-185 L Transposase
KCOEDOJP_01361 1.6e-18 L Integrase core domain
KCOEDOJP_01362 6e-109 devA 3.6.3.25 V abc transporter atp-binding protein
KCOEDOJP_01363 2.8e-164 hrtB V MacB-like periplasmic core domain
KCOEDOJP_01366 3e-92 S MucBP domain
KCOEDOJP_01367 5.9e-51 M YSIRK type signal peptide
KCOEDOJP_01369 1.5e-39 L Integrase core domain
KCOEDOJP_01370 1.5e-46 waaB GT4 M Glycosyl transferases group 1
KCOEDOJP_01371 1.5e-07 cps2J S Polysaccharide biosynthesis protein
KCOEDOJP_01372 5e-148 L DDE domain
KCOEDOJP_01373 2.1e-42 L Transposase
KCOEDOJP_01374 1.4e-11 L EVIDENCE BY HOMOLOGY BIO14.04 Transposon related functions. orf1 of IS981
KCOEDOJP_01375 5.5e-29 capM K Cell envelope-related transcriptional attenuator domain
KCOEDOJP_01376 2.5e-98 capM K Cell envelope-related transcriptional attenuator domain
KCOEDOJP_01377 2.6e-112 L Transposase
KCOEDOJP_01378 2e-71 L Transposase
KCOEDOJP_01379 2.9e-94 V VanZ like family
KCOEDOJP_01380 1.1e-15 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KCOEDOJP_01381 3.7e-60 supH 3.1.3.102, 3.1.3.104 Q phosphatase activity
KCOEDOJP_01382 3.9e-102 G Belongs to the phosphoglycerate mutase family
KCOEDOJP_01383 1e-196 S hmm pf01594
KCOEDOJP_01384 8.4e-27 bglH 3.2.1.86 GT1 G beta-glucosidase activity
KCOEDOJP_01385 7.7e-67 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCOEDOJP_01386 3.8e-43 bglH 3.2.1.86 GT1 G beta-glucosidase activity
KCOEDOJP_01387 7.1e-36 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KCOEDOJP_01388 4.9e-39 S granule-associated protein
KCOEDOJP_01389 1.2e-291 S unusual protein kinase
KCOEDOJP_01390 3.4e-29 estA E Lysophospholipase L1 and related esterases
KCOEDOJP_01391 5.3e-69 estA E GDSL-like protein
KCOEDOJP_01392 6.7e-156 rssA S Phospholipase, patatin family
KCOEDOJP_01393 4.7e-71
KCOEDOJP_01394 2e-113 3.1.21.3 V type I restriction modification DNA specificity domain protein
KCOEDOJP_01395 9.5e-297 hsdM 2.1.1.72 V HsdM N-terminal domain
KCOEDOJP_01396 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KCOEDOJP_01397 2.4e-26
KCOEDOJP_01398 6.9e-262 yfiB1 V abc transporter atp-binding protein
KCOEDOJP_01399 0.0 XK27_10035 V abc transporter atp-binding protein
KCOEDOJP_01400 1.5e-09 S D-Ala-teichoic acid biosynthesis protein
KCOEDOJP_01401 1.4e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCOEDOJP_01402 3.9e-237 dltB M Membrane protein involved in D-alanine export
KCOEDOJP_01403 1.7e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KCOEDOJP_01404 4.7e-230 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KCOEDOJP_01405 7e-33 L Integrase core domain protein
KCOEDOJP_01406 1.9e-59 S Uncharacterised lipoprotein family
KCOEDOJP_01407 1.5e-75 tspO T TspO/MBR family
KCOEDOJP_01408 2.6e-44 pepD E Dipeptidase
KCOEDOJP_01409 6.8e-81 pepD E Dipeptidase
KCOEDOJP_01410 8.7e-162 whiA K May be required for sporulation
KCOEDOJP_01411 2.8e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KCOEDOJP_01412 1.2e-163 rapZ S Displays ATPase and GTPase activities
KCOEDOJP_01413 7e-136 yejC S cyclic nucleotide-binding protein
KCOEDOJP_01414 4.2e-18 D nuclear chromosome segregation
KCOEDOJP_01415 7.9e-41 L COG1943 Transposase and inactivated derivatives
KCOEDOJP_01416 1.3e-221 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KCOEDOJP_01417 2.4e-30
KCOEDOJP_01418 1.5e-12
KCOEDOJP_01419 1.3e-87 S Fusaric acid resistance protein-like
KCOEDOJP_01420 8.5e-63 glnR K Transcriptional regulator
KCOEDOJP_01421 9.9e-263 glnA 6.3.1.2 E glutamine synthetase
KCOEDOJP_01422 1.1e-41 pscB M CHAP domain protein
KCOEDOJP_01423 7.2e-86 L transposition
KCOEDOJP_01424 0.0 M family 8
KCOEDOJP_01425 2.7e-09
KCOEDOJP_01426 5.6e-08
KCOEDOJP_01427 5.8e-109 MA20_06410 E LysE type translocator
KCOEDOJP_01428 6.9e-08 IQ PFAM AMP-dependent synthetase and ligase
KCOEDOJP_01430 3.2e-12 6.3.2.2 H gamma-glutamylcysteine synthetase
KCOEDOJP_01431 1.5e-65 6.3.2.2 H gamma-glutamylcysteine synthetase
KCOEDOJP_01432 1.1e-109 6.3.2.2 H ergothioneine biosynthetic process
KCOEDOJP_01434 4.8e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
KCOEDOJP_01435 3.6e-132 L DNA integration
KCOEDOJP_01436 4.3e-41 pssE S Glycosyltransferase family 28 C-terminal domain
KCOEDOJP_01437 5.9e-73 M Glycosyltransferase sugar-binding region containing DXD motif
KCOEDOJP_01438 2.3e-15
KCOEDOJP_01439 8.9e-09 2.4.1.166 GT2 M Glycosyltransferase like family 2
KCOEDOJP_01440 2.4e-92 pat 2.3.1.183 M acetyltransferase
KCOEDOJP_01441 8.1e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KCOEDOJP_01442 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KCOEDOJP_01443 7.1e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KCOEDOJP_01444 0.0 smc D Required for chromosome condensation and partitioning
KCOEDOJP_01445 9.6e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KCOEDOJP_01446 9.9e-94 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KCOEDOJP_01447 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KCOEDOJP_01450 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
KCOEDOJP_01451 1.4e-239 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KCOEDOJP_01453 2e-86 S ECF-type riboflavin transporter, S component
KCOEDOJP_01454 5.5e-42 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KCOEDOJP_01455 9.3e-87 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
KCOEDOJP_01456 5.6e-84 XK27_01265 S ECF-type riboflavin transporter, S component
KCOEDOJP_01457 9.5e-294 yfmM S abc transporter atp-binding protein
KCOEDOJP_01458 4.4e-258 noxE P NADH oxidase
KCOEDOJP_01459 1.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KCOEDOJP_01460 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KCOEDOJP_01461 1.7e-134 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
KCOEDOJP_01462 3.9e-53 yaeR E COG0346 LactoylglutaTHIone lyase and related lyases
KCOEDOJP_01463 1.8e-165 ypuA S secreted protein
KCOEDOJP_01464 3.3e-26 L Transposase (IS116 IS110 IS902 family)
KCOEDOJP_01465 4.2e-71 L Transposase (IS116 IS110 IS902 family)
KCOEDOJP_01467 1.7e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCOEDOJP_01468 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KCOEDOJP_01469 8.5e-34 nrdH O Glutaredoxin
KCOEDOJP_01470 4.5e-85 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCOEDOJP_01471 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KCOEDOJP_01472 9.6e-211 citZ 2.3.3.1 C Belongs to the citrate synthase family
KCOEDOJP_01473 1.1e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
KCOEDOJP_01474 7.9e-39 ptsH G phosphocarrier protein Hpr
KCOEDOJP_01475 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KCOEDOJP_01476 1.9e-264 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
KCOEDOJP_01477 4.8e-28 6.3.2.2, 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KCOEDOJP_01478 8.7e-177 yfmL 3.6.4.13 L DEAD DEAH box helicase
KCOEDOJP_01479 2.1e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KCOEDOJP_01480 0.0 uup S abc transporter atp-binding protein
KCOEDOJP_01481 2.2e-131 pip 1.11.1.10 S Alpha beta hydrolase
KCOEDOJP_01482 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KCOEDOJP_01483 8.7e-150 cobQ S glutamine amidotransferase
KCOEDOJP_01484 7.5e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
KCOEDOJP_01485 5.6e-124 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KCOEDOJP_01486 6e-169 ybbR S Protein conserved in bacteria
KCOEDOJP_01487 1.5e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KCOEDOJP_01488 1.7e-70 gtrA S GtrA-like protein
KCOEDOJP_01489 2.7e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
KCOEDOJP_01490 9.6e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KCOEDOJP_01491 5.7e-102 zupT P Mediates zinc uptake. May also transport other divalent cations
KCOEDOJP_01492 6.3e-207 yurR 1.4.5.1 E oxidoreductase
KCOEDOJP_01493 1.9e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KCOEDOJP_01494 8.3e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KCOEDOJP_01495 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KCOEDOJP_01499 4.1e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KCOEDOJP_01500 1.5e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
KCOEDOJP_01501 5.9e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KCOEDOJP_01502 1.1e-121 ylfI S tigr01906
KCOEDOJP_01503 2e-140 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
KCOEDOJP_01504 2.3e-09 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KCOEDOJP_01505 1.4e-87 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
KCOEDOJP_01506 2.2e-33 XK27_08085
KCOEDOJP_01507 5.2e-36 L transposase activity
KCOEDOJP_01508 8.2e-22 L Transposase
KCOEDOJP_01509 1.9e-48 L transposition
KCOEDOJP_01510 3.1e-27 L Integrase core domain protein
KCOEDOJP_01512 1.1e-195 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KCOEDOJP_01513 5.7e-183 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KCOEDOJP_01514 5.2e-116 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KCOEDOJP_01515 1.1e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KCOEDOJP_01516 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KCOEDOJP_01517 9.8e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KCOEDOJP_01518 1.7e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KCOEDOJP_01519 9.6e-138 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KCOEDOJP_01520 5.5e-61 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KCOEDOJP_01521 1.8e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP
KCOEDOJP_01522 5.6e-240 rodA D Belongs to the SEDS family
KCOEDOJP_01523 5.4e-197 L transposase, IS4 family
KCOEDOJP_01524 5.4e-223 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KCOEDOJP_01525 1e-116 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
KCOEDOJP_01526 1e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KCOEDOJP_01527 6.7e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KCOEDOJP_01528 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
KCOEDOJP_01529 2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KCOEDOJP_01530 9.3e-183 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KCOEDOJP_01531 2.9e-125 dnaD
KCOEDOJP_01532 3.4e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KCOEDOJP_01535 1.2e-247 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KCOEDOJP_01536 3.5e-29 xseB 3.1.11.6 L exodeoxyribonuclease VII activity
KCOEDOJP_01537 3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KCOEDOJP_01538 5e-159 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KCOEDOJP_01539 3.7e-73 argR K Regulates arginine biosynthesis genes
KCOEDOJP_01540 5.8e-305 recN L May be involved in recombinational repair of damaged DNA
KCOEDOJP_01541 1e-148 DegV S DegV family
KCOEDOJP_01542 6e-144 ypmR E lipolytic protein G-D-S-L family
KCOEDOJP_01543 2.1e-84 ypmS S Protein conserved in bacteria
KCOEDOJP_01544 2.8e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KCOEDOJP_01546 2.5e-180 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
KCOEDOJP_01547 4.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KCOEDOJP_01548 5.9e-291 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KCOEDOJP_01549 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KCOEDOJP_01550 1.3e-42 ysdA L Membrane
KCOEDOJP_01551 6.8e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCOEDOJP_01552 3.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KCOEDOJP_01553 1.4e-152 sua5 2.7.7.87 J Belongs to the SUA5 family
KCOEDOJP_01554 0.0 dnaE 2.7.7.7 L DNA polymerase
KCOEDOJP_01555 2.1e-188 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KCOEDOJP_01556 6.7e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KCOEDOJP_01557 1.2e-88 adk 2.7.4.3 F topology modulation protein
KCOEDOJP_01558 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KCOEDOJP_01559 7.1e-28 L transposase activity
KCOEDOJP_01561 1.7e-25
KCOEDOJP_01562 9.3e-32 cspD K Cold shock protein domain
KCOEDOJP_01563 3.6e-42 K Cold-Shock Protein
KCOEDOJP_01564 2.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KCOEDOJP_01565 1.8e-51 amd 3.5.1.47 E Peptidase dimerisation domain
KCOEDOJP_01566 1.7e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KCOEDOJP_01567 1.2e-165 L integrase core domain
KCOEDOJP_01568 1.1e-121 L Transposase
KCOEDOJP_01569 4.1e-181 L Transposase
KCOEDOJP_01570 2.1e-115 L PFAM Integrase, catalytic core
KCOEDOJP_01571 1.9e-33 L PFAM Integrase, catalytic core
KCOEDOJP_01572 7e-43 L Transposase
KCOEDOJP_01573 1.7e-48 adk 2.7.4.3 F topology modulation protein
KCOEDOJP_01574 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KCOEDOJP_01575 2.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KCOEDOJP_01576 2.3e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KCOEDOJP_01577 2.8e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KCOEDOJP_01578 2.8e-18 M LysM domain
KCOEDOJP_01579 2.9e-90 ebsA S Family of unknown function (DUF5322)
KCOEDOJP_01580 4.2e-228 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KCOEDOJP_01581 4.3e-95 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KCOEDOJP_01582 4.5e-222 G COG0457 FOG TPR repeat
KCOEDOJP_01583 6.2e-176 yubA S permease
KCOEDOJP_01584 4.6e-93 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
KCOEDOJP_01585 4.7e-163 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KCOEDOJP_01586 2.5e-124 ftsE D cell division ATP-binding protein FtsE
KCOEDOJP_01587 7.4e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KCOEDOJP_01588 1.2e-202 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KCOEDOJP_01589 1e-181 yjjH S Calcineurin-like phosphoesterase
KCOEDOJP_01590 3.3e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KCOEDOJP_01591 0.0 pacL 3.6.3.8 P cation transport ATPase
KCOEDOJP_01592 3.4e-67 ywiB S Domain of unknown function (DUF1934)
KCOEDOJP_01593 1.4e-50 XK27_00115 2.3.1.128 K acetyltransferase
KCOEDOJP_01594 9.2e-147 yidA S hydrolases of the HAD superfamily
KCOEDOJP_01595 9e-231 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
KCOEDOJP_01596 1e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
KCOEDOJP_01597 1.5e-247 vicK 2.7.13.3 T Histidine kinase
KCOEDOJP_01598 9.9e-129 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCOEDOJP_01599 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
KCOEDOJP_01600 9.2e-150 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
KCOEDOJP_01601 8e-115 gltJ P ABC transporter (Permease
KCOEDOJP_01602 2.5e-110 tcyB_2 P ABC transporter (permease)
KCOEDOJP_01603 1.1e-142 endA F DNA RNA non-specific endonuclease
KCOEDOJP_01604 1.2e-25 epuA S DNA-directed RNA polymerase subunit beta
KCOEDOJP_01605 3.2e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KCOEDOJP_01607 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCOEDOJP_01608 2.8e-131 G Domain of unknown function (DUF4832)
KCOEDOJP_01609 1.6e-33 P VTC domain
KCOEDOJP_01610 3.9e-47 P VTC domain
KCOEDOJP_01611 4.1e-218 cotH M CotH kinase protein
KCOEDOJP_01612 3.1e-185 pelG M Putative exopolysaccharide Exporter (EPS-E)
KCOEDOJP_01613 1.3e-276 pelF GT4 M Domain of unknown function (DUF3492)
KCOEDOJP_01614 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KCOEDOJP_01615 4.6e-139
KCOEDOJP_01616 4.2e-194 5.1.3.2 GM Psort location CytoplasmicMembrane, score
KCOEDOJP_01617 8.4e-42 5.1.3.2 GM Psort location CytoplasmicMembrane, score
KCOEDOJP_01618 2.1e-203 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KCOEDOJP_01619 4.2e-175 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KCOEDOJP_01620 3.2e-295 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KCOEDOJP_01621 3.9e-87 ytsP 1.8.4.14 T GAF domain-containing protein
KCOEDOJP_01622 7.1e-164 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KCOEDOJP_01623 1.2e-19 WQ51_02665 S Protein of unknown function (DUF3042)
KCOEDOJP_01625 1.6e-230 L Transposase
KCOEDOJP_01627 8.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KCOEDOJP_01628 3.4e-217 XK27_05110 P chloride
KCOEDOJP_01629 8.7e-41 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
KCOEDOJP_01630 1.9e-281 clcA P Chloride transporter, ClC family
KCOEDOJP_01631 1e-75 fld C Flavodoxin
KCOEDOJP_01632 3.3e-14 XK27_08880
KCOEDOJP_01633 1.1e-124 XK27_08875 O Zinc-dependent metalloprotease
KCOEDOJP_01634 6e-151 estA CE1 S Putative esterase
KCOEDOJP_01635 6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KCOEDOJP_01636 1.2e-135 XK27_08845 S abc transporter atp-binding protein
KCOEDOJP_01637 8.9e-148 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
KCOEDOJP_01638 1.1e-173 XK27_08835 S ABC transporter substrate binding protein
KCOEDOJP_01639 3.2e-17 S Domain of unknown function (DUF4649)
KCOEDOJP_01640 1.1e-27 Q the current gene model (or a revised gene model) may contain a frame shift
KCOEDOJP_01641 1.1e-27 Q the current gene model (or a revised gene model) may contain a frame shift
KCOEDOJP_01649 1.6e-42 hsdM 2.1.1.72 V type I restriction-modification system
KCOEDOJP_01650 9.6e-43 hsdM 2.1.1.72 V type I restriction-modification system
KCOEDOJP_01651 9e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KCOEDOJP_01652 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KCOEDOJP_01653 3.9e-37 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KCOEDOJP_01654 8.6e-22 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
KCOEDOJP_01655 1.2e-62 bioY S biotin transmembrane transporter activity
KCOEDOJP_01656 9.8e-88 proW P Binding-protein-dependent transport system inner membrane component
KCOEDOJP_01657 2.1e-137 proV E abc transporter atp-binding protein
KCOEDOJP_01658 2e-169 proX M ABC transporter, substrate-binding protein, QAT family
KCOEDOJP_01659 3e-111 proWZ P ABC transporter (Permease
KCOEDOJP_01660 1.4e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
KCOEDOJP_01661 5.4e-206 S Protein of unknown function (DUF917)
KCOEDOJP_01662 1.3e-309 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KCOEDOJP_01663 1.6e-59 sdaAB 4.3.1.17 E L-serine dehydratase
KCOEDOJP_01664 1.7e-100 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KCOEDOJP_01665 2e-192 desK 2.7.13.3 T Histidine kinase
KCOEDOJP_01666 4.5e-132 yvfS V ABC-2 type transporter
KCOEDOJP_01667 1.5e-158 XK27_09825 V abc transporter atp-binding protein
KCOEDOJP_01671 3.3e-212 EGP Major facilitator Superfamily
KCOEDOJP_01672 0.0 2.7.7.73, 2.7.7.80 E metalloendopeptidase activity
KCOEDOJP_01673 7.9e-152 mutR K Transcriptional activator, Rgg GadR MutR family
KCOEDOJP_01674 4.6e-42 3.6.1.55 F NUDIX domain
KCOEDOJP_01676 3.7e-122 S An automated process has identified a potential problem with this gene model
KCOEDOJP_01677 6.1e-26 XK27_09825 V 'abc transporter, ATP-binding protein
KCOEDOJP_01678 1.4e-15 liaI KT membrane
KCOEDOJP_01679 2.6e-30 liaI KT membrane
KCOEDOJP_01680 6e-99 XK27_05000 S Fe-S-cluster oxidoreductase
KCOEDOJP_01681 0.0 V ABC transporter (permease)
KCOEDOJP_01682 1.9e-133 macB2 V ABC transporter, ATP-binding protein
KCOEDOJP_01683 6.2e-166 T Histidine kinase
KCOEDOJP_01684 3.9e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCOEDOJP_01685 2e-77 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KCOEDOJP_01687 1.5e-69 pbuX F xanthine permease
KCOEDOJP_01688 1.1e-119 pbuX F xanthine permease
KCOEDOJP_01689 1.5e-247 norM V Multidrug efflux pump
KCOEDOJP_01690 9.7e-188 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KCOEDOJP_01691 3.3e-234 brnQ E Component of the transport system for branched-chain amino acids
KCOEDOJP_01692 9.4e-65 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCOEDOJP_01693 8.2e-57 manA 5.3.1.8 G mannose-6-phosphate isomerase
KCOEDOJP_01694 4.8e-25 csbD K CsbD-like
KCOEDOJP_01695 6.2e-228 yfnA E amino acid
KCOEDOJP_01696 5.1e-110 XK27_02070 S nitroreductase
KCOEDOJP_01697 3.7e-154 1.13.11.2 S glyoxalase
KCOEDOJP_01698 5.6e-77 ywnA K Transcriptional regulator
KCOEDOJP_01699 8.6e-159 E Alpha/beta hydrolase of unknown function (DUF915)
KCOEDOJP_01700 5.6e-231 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KCOEDOJP_01701 1.4e-110 drgA C Nitroreductase
KCOEDOJP_01702 2.3e-108 yoaK S Protein of unknown function (DUF1275)
KCOEDOJP_01703 6.8e-161 yvgN C reductase
KCOEDOJP_01704 7.3e-103 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KCOEDOJP_01705 2.4e-09
KCOEDOJP_01706 1.6e-140 S Abortive infection C-terminus
KCOEDOJP_01707 0.0 L DEAD-like helicases superfamily
KCOEDOJP_01708 1.4e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KCOEDOJP_01709 3.6e-282 XK27_07020 S Belongs to the UPF0371 family
KCOEDOJP_01711 1.1e-37 BP1961 P nitric oxide dioxygenase activity
KCOEDOJP_01712 4.8e-55 K response regulator
KCOEDOJP_01713 1.8e-70 S Signal peptide protein, YSIRK family
KCOEDOJP_01715 2.2e-60
KCOEDOJP_01716 7e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KCOEDOJP_01717 1.3e-130
KCOEDOJP_01718 2.8e-10 IQ PFAM AMP-dependent synthetase and ligase
KCOEDOJP_01719 2.3e-33 L Transposase
KCOEDOJP_01723 2.6e-10
KCOEDOJP_01726 1.6e-77 sigH K DNA-templated transcription, initiation
KCOEDOJP_01727 6e-149 ykuT M mechanosensitive ion channel
KCOEDOJP_01728 6.4e-219 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KCOEDOJP_01729 4.8e-73 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KCOEDOJP_01730 7.6e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KCOEDOJP_01731 1.3e-84 XK27_03960 S Protein of unknown function (DUF3013)
KCOEDOJP_01732 3.7e-81 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
KCOEDOJP_01733 9.1e-178 prmA J Ribosomal protein L11 methyltransferase
KCOEDOJP_01734 4.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KCOEDOJP_01735 1.4e-42 F nucleotide catabolic process
KCOEDOJP_01736 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KCOEDOJP_01737 2.4e-83 nrdI F Belongs to the NrdI family
KCOEDOJP_01738 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KCOEDOJP_01739 2.3e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KCOEDOJP_01740 1.4e-09 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCOEDOJP_01741 2e-27 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCOEDOJP_01742 2.1e-58 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCOEDOJP_01743 3.9e-46 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
KCOEDOJP_01744 1.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KCOEDOJP_01745 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KCOEDOJP_01746 1.1e-113 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
KCOEDOJP_01747 6.5e-202 yhjX P Major Facilitator
KCOEDOJP_01748 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KCOEDOJP_01749 5e-94 V VanZ like family
KCOEDOJP_01751 1e-123 glnQ E abc transporter atp-binding protein
KCOEDOJP_01752 5.3e-276 glnP P ABC transporter
KCOEDOJP_01753 2e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KCOEDOJP_01754 1.2e-135 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KCOEDOJP_01755 1.8e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
KCOEDOJP_01756 9.5e-144 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KCOEDOJP_01757 6.3e-235 sufD O assembly protein SufD
KCOEDOJP_01758 7.7e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KCOEDOJP_01759 2.5e-74 nifU C SUF system FeS assembly protein, NifU family
KCOEDOJP_01760 3.5e-274 sufB O assembly protein SufB
KCOEDOJP_01761 2.4e-19 oppA E ABC transporter substrate-binding protein
KCOEDOJP_01762 1.4e-133 oppA E ABC transporter substrate-binding protein
KCOEDOJP_01763 4.2e-27 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCOEDOJP_01764 6.6e-11 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCOEDOJP_01765 5.4e-46 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCOEDOJP_01766 5.3e-60 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
KCOEDOJP_01767 8e-28 oppD P Belongs to the ABC transporter superfamily
KCOEDOJP_01768 2.5e-32 oppD P Belongs to the ABC transporter superfamily
KCOEDOJP_01769 4.8e-67 oppD P Belongs to the ABC transporter superfamily
KCOEDOJP_01770 1.7e-30 oppD P Belongs to the ABC transporter superfamily
KCOEDOJP_01771 3.4e-169 oppF P Belongs to the ABC transporter superfamily
KCOEDOJP_01774 4.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KCOEDOJP_01775 7.4e-183 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KCOEDOJP_01776 1.9e-223 EGP Major facilitator Superfamily
KCOEDOJP_01777 3.1e-72 adcR K transcriptional
KCOEDOJP_01778 6.4e-136 adcC P ABC transporter, ATP-binding protein
KCOEDOJP_01779 1.7e-129 adcB P ABC transporter (Permease
KCOEDOJP_01780 6.2e-163 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
KCOEDOJP_01781 5.6e-65 ptsG 2.7.1.199, 2.7.1.208 G pts system
KCOEDOJP_01782 6e-150 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G pts system
KCOEDOJP_01783 1.1e-81 ptsG 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KCOEDOJP_01784 4.2e-149 rgfB 3.1.3.90 L endonuclease exonuclease phosphatase family protein
KCOEDOJP_01785 2.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
KCOEDOJP_01786 1.9e-127 yeeN K transcriptional regulatory protein
KCOEDOJP_01787 9.8e-50 yajC U protein transport
KCOEDOJP_01788 1.1e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KCOEDOJP_01789 2.2e-145 cdsA 2.7.7.41 S Belongs to the CDS family
KCOEDOJP_01790 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KCOEDOJP_01791 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KCOEDOJP_01792 0.0 WQ51_06230 S ABC transporter substrate binding protein
KCOEDOJP_01793 5.2e-142 cmpC S abc transporter atp-binding protein
KCOEDOJP_01794 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KCOEDOJP_01795 4.1e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KCOEDOJP_01796 4.4e-37 L Transposase
KCOEDOJP_01797 3.2e-17 L transposase activity
KCOEDOJP_01798 2.5e-115 L Transposase
KCOEDOJP_01799 2.9e-246 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KCOEDOJP_01800 3.4e-239 agcS E (Alanine) symporter
KCOEDOJP_01801 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KCOEDOJP_01802 1.7e-240 metY 2.5.1.49 E o-acetylhomoserine
KCOEDOJP_01803 1.7e-134 S haloacid dehalogenase-like hydrolase
KCOEDOJP_01804 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KCOEDOJP_01805 1.1e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
KCOEDOJP_01806 6.3e-32 M1-755 P Hemerythrin HHE cation binding domain protein
KCOEDOJP_01807 5.4e-95 XK27_04775 S hemerythrin HHE cation binding domain
KCOEDOJP_01808 2.6e-49 XK27_04775 S hemerythrin HHE cation binding domain
KCOEDOJP_01809 4.9e-151 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KCOEDOJP_01810 5.3e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KCOEDOJP_01811 1.4e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KCOEDOJP_01812 1.9e-43 yktA S Belongs to the UPF0223 family
KCOEDOJP_01813 5e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KCOEDOJP_01814 3e-256 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KCOEDOJP_01815 3.3e-158 pstS P phosphate
KCOEDOJP_01816 2.5e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KCOEDOJP_01817 2.9e-154 pstA P phosphate transport system permease
KCOEDOJP_01818 5.2e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCOEDOJP_01819 1.7e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KCOEDOJP_01820 9.2e-113 phoU P Plays a role in the regulation of phosphate uptake
KCOEDOJP_01821 0.0 pepN 3.4.11.2 E aminopeptidase
KCOEDOJP_01822 1.6e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
KCOEDOJP_01823 3.2e-186 lplA 6.3.1.20 H Lipoate-protein ligase
KCOEDOJP_01826 3.7e-09
KCOEDOJP_01827 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KCOEDOJP_01828 9.9e-304 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
KCOEDOJP_01829 2.3e-23 L Transposase
KCOEDOJP_01830 4.6e-25 tatA U protein secretion
KCOEDOJP_01831 5.8e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KCOEDOJP_01832 2.6e-300 ywbL P COG0672 High-affinity Fe2 Pb2 permease
KCOEDOJP_01833 1.5e-233 ycdB P peroxidase
KCOEDOJP_01834 2.1e-152 ycdO P periplasmic lipoprotein involved in iron transport
KCOEDOJP_01835 3e-34 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCOEDOJP_01836 3.7e-85 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCOEDOJP_01837 1.7e-60 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCOEDOJP_01838 1.2e-65 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCOEDOJP_01839 2.4e-134 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
KCOEDOJP_01840 1.9e-37 3.5.1.28 NU amidase activity
KCOEDOJP_01841 3.2e-265 3.5.1.28 NU amidase activity
KCOEDOJP_01842 3.6e-82 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCOEDOJP_01843 2.6e-20 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
KCOEDOJP_01844 0.0 lpdA 1.8.1.4 C Dehydrogenase
KCOEDOJP_01845 1.3e-198 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KCOEDOJP_01846 3.7e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KCOEDOJP_01847 1e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KCOEDOJP_01848 0.0 S the current gene model (or a revised gene model) may contain a frame shift
KCOEDOJP_01849 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KCOEDOJP_01850 2.9e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KCOEDOJP_01851 8.6e-218 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KCOEDOJP_01852 3e-27 L Integrase core domain protein
KCOEDOJP_01853 1.2e-34
KCOEDOJP_01855 5.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KCOEDOJP_01856 4e-167 dnaI L Primosomal protein DnaI
KCOEDOJP_01857 1.4e-217 dnaB L Replication initiation and membrane attachment
KCOEDOJP_01858 2.8e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KCOEDOJP_01859 8e-277 T PhoQ Sensor
KCOEDOJP_01860 1.8e-122 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KCOEDOJP_01861 8.1e-91 yceD K metal-binding, possibly nucleic acid-binding protein
KCOEDOJP_01862 9e-130 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
KCOEDOJP_01863 9.8e-242 P COG0168 Trk-type K transport systems, membrane components
KCOEDOJP_01864 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
KCOEDOJP_01865 1.4e-11 ulaG S L-ascorbate 6-phosphate lactonase
KCOEDOJP_01866 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KCOEDOJP_01867 2e-149 cbiQ P cobalt transport
KCOEDOJP_01868 0.0 ykoD P abc transporter atp-binding protein
KCOEDOJP_01869 9.4e-95 S UPF0397 protein
KCOEDOJP_01870 3.2e-158 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
KCOEDOJP_01871 6.7e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KCOEDOJP_01872 8.8e-98 metI P ABC transporter (Permease
KCOEDOJP_01873 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KCOEDOJP_01874 1e-63 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KCOEDOJP_01875 1.4e-62 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase activity
KCOEDOJP_01876 1.2e-82 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
KCOEDOJP_01877 3.7e-165 metQ M Belongs to the NlpA lipoprotein family
KCOEDOJP_01878 7.1e-150 ET amino acid transport
KCOEDOJP_01879 1.6e-131 cbiO P ABC transporter
KCOEDOJP_01880 1.1e-136 P cobalt transport protein
KCOEDOJP_01881 2.7e-177 cbiM P PDGLE domain
KCOEDOJP_01882 3.7e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KCOEDOJP_01883 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KCOEDOJP_01884 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KCOEDOJP_01885 6.6e-78 ureE O enzyme active site formation
KCOEDOJP_01886 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KCOEDOJP_01887 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KCOEDOJP_01888 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KCOEDOJP_01889 6.8e-95 ureI S AmiS/UreI family transporter
KCOEDOJP_01890 9.2e-132 S Domain of unknown function (DUF4173)
KCOEDOJP_01891 6.7e-36 S Domain of unknown function (DUF4173)
KCOEDOJP_01892 3.7e-51 yhaI L Membrane
KCOEDOJP_01893 3.4e-68 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCOEDOJP_01894 1.1e-36 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCOEDOJP_01895 3.4e-62 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
KCOEDOJP_01896 1.9e-33 V protein secretion by the type I secretion system
KCOEDOJP_01897 2.5e-161 K sequence-specific DNA binding
KCOEDOJP_01898 8.3e-114 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
KCOEDOJP_01899 6.4e-91 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KCOEDOJP_01900 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KCOEDOJP_01901 1.5e-247 trkA P Potassium transporter peripheral membrane component
KCOEDOJP_01902 1.2e-258 trkH P Cation transport protein
KCOEDOJP_01903 8e-41 yidD S Could be involved in insertion of integral membrane proteins into the membrane
KCOEDOJP_01904 4.6e-140 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KCOEDOJP_01905 3e-99 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KCOEDOJP_01906 3.1e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KCOEDOJP_01907 3.7e-137 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
KCOEDOJP_01908 5.4e-86 ykuL S CBS domain
KCOEDOJP_01909 3.5e-99 XK27_09740 S Phosphoesterase
KCOEDOJP_01910 7.1e-186 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KCOEDOJP_01911 3.2e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KCOEDOJP_01912 7.6e-36 yneF S UPF0154 protein
KCOEDOJP_01913 8.1e-91 K transcriptional regulator
KCOEDOJP_01914 7.3e-244 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)