ORF_ID e_value Gene_name EC_number CAZy COGs Description
JOHLMJPM_00001 1.4e-175 L Integrase core domain
JOHLMJPM_00002 7.5e-103 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00003 1.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
JOHLMJPM_00004 8.3e-114 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
JOHLMJPM_00005 2.6e-180 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
JOHLMJPM_00006 3.4e-149 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOHLMJPM_00007 5.2e-136 K Bacterial transcriptional regulator
JOHLMJPM_00008 4.8e-244 gatC G PTS system sugar-specific permease component
JOHLMJPM_00010 5.6e-130 IQ reductase
JOHLMJPM_00011 6.4e-241 mntH P H( )-stimulated, divalent metal cation uptake system
JOHLMJPM_00012 3.7e-154 S Uncharacterised protein, DegV family COG1307
JOHLMJPM_00013 2.5e-269 nox C NADH oxidase
JOHLMJPM_00014 2.3e-56 trxA1 O Belongs to the thioredoxin family
JOHLMJPM_00015 1.3e-38 yrkD S Metal-sensitive transcriptional repressor
JOHLMJPM_00016 3.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOHLMJPM_00017 5.4e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JOHLMJPM_00018 4.2e-150 M1-1017
JOHLMJPM_00019 3.9e-164 I Carboxylesterase family
JOHLMJPM_00020 3.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
JOHLMJPM_00021 4.5e-165
JOHLMJPM_00022 2.5e-250 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOHLMJPM_00023 2.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
JOHLMJPM_00024 1e-156 lysR5 K LysR substrate binding domain
JOHLMJPM_00025 9e-145 yxaA S membrane transporter protein
JOHLMJPM_00026 5.4e-57 ywjH S Protein of unknown function (DUF1634)
JOHLMJPM_00027 7.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
JOHLMJPM_00028 6.8e-226 mdtG EGP Major facilitator Superfamily
JOHLMJPM_00029 8.9e-18 2.7.6.5 S RelA SpoT domain protein
JOHLMJPM_00030 6.6e-53 2.7.6.5 S RelA SpoT domain protein
JOHLMJPM_00031 8.1e-28 S Protein of unknown function (DUF2929)
JOHLMJPM_00032 5.5e-169 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JOHLMJPM_00034 0.0 S membrane
JOHLMJPM_00035 8.5e-125 K cheY-homologous receiver domain
JOHLMJPM_00036 1.1e-245 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
JOHLMJPM_00037 1.8e-181 malR K Transcriptional regulator, LacI family
JOHLMJPM_00038 4.5e-255 malT G Major Facilitator
JOHLMJPM_00039 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
JOHLMJPM_00040 2.4e-77
JOHLMJPM_00041 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JOHLMJPM_00042 2.7e-151 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JOHLMJPM_00043 2.1e-162 S Alpha/beta hydrolase of unknown function (DUF915)
JOHLMJPM_00044 4.3e-152 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
JOHLMJPM_00045 4.6e-64 K MarR family
JOHLMJPM_00046 6.2e-252 yclG M Parallel beta-helix repeats
JOHLMJPM_00047 2.7e-73 spx4 1.20.4.1 P ArsC family
JOHLMJPM_00048 4.1e-144 iap CBM50 M NlpC/P60 family
JOHLMJPM_00049 4.8e-173 K acetyltransferase
JOHLMJPM_00050 5.1e-298 E dipeptidase activity
JOHLMJPM_00051 6.9e-69 S membrane transporter protein
JOHLMJPM_00052 7e-50 S membrane transporter protein
JOHLMJPM_00053 6.1e-126 IQ Enoyl-(Acyl carrier protein) reductase
JOHLMJPM_00054 1.8e-226 G Major Facilitator
JOHLMJPM_00055 0.0 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JOHLMJPM_00056 3e-153 3.2.1.37 GH43 K helix_turn_helix, arabinose operon control protein
JOHLMJPM_00057 1.9e-133 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOHLMJPM_00058 5.7e-155 1.6.5.2 GM NmrA-like family
JOHLMJPM_00059 1.4e-72 K Transcriptional regulator
JOHLMJPM_00060 0.0 2.7.8.12 M glycerophosphotransferase
JOHLMJPM_00061 7.4e-45 2.7.8.12 M glycerophosphotransferase
JOHLMJPM_00062 2.8e-171
JOHLMJPM_00063 6.3e-63 K Transcriptional regulator, HxlR family
JOHLMJPM_00064 3.9e-202 ytbD EGP Major facilitator Superfamily
JOHLMJPM_00065 7.2e-183 S Aldo keto reductase
JOHLMJPM_00066 1.8e-136 cysA V ABC transporter, ATP-binding protein
JOHLMJPM_00067 0.0 Q FtsX-like permease family
JOHLMJPM_00068 3.5e-61 gntR1 K Transcriptional regulator, GntR family
JOHLMJPM_00069 2.7e-70 S Iron-sulphur cluster biosynthesis
JOHLMJPM_00070 1.2e-196 sdrF M Collagen binding domain
JOHLMJPM_00071 0.0 cadA P P-type ATPase
JOHLMJPM_00072 5.6e-121 S SNARE associated Golgi protein
JOHLMJPM_00073 0.0 mco Q Multicopper oxidase
JOHLMJPM_00074 9.4e-53 czrA K Transcriptional regulator, ArsR family
JOHLMJPM_00075 3.6e-103 P Cadmium resistance transporter
JOHLMJPM_00076 2.9e-161 MA20_14895 S Conserved hypothetical protein 698
JOHLMJPM_00077 2.9e-154 K LysR substrate binding domain
JOHLMJPM_00078 5e-210 norA EGP Major facilitator Superfamily
JOHLMJPM_00079 5.9e-160 K helix_turn_helix, arabinose operon control protein
JOHLMJPM_00080 4.5e-311 ybiT S ABC transporter, ATP-binding protein
JOHLMJPM_00081 1.4e-175 L Integrase core domain
JOHLMJPM_00082 8.2e-174 2.7.7.7, 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JOHLMJPM_00083 5.3e-233 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
JOHLMJPM_00084 5.7e-94 L 4.5 Transposon and IS
JOHLMJPM_00085 3.9e-10 L Transposase
JOHLMJPM_00086 2e-192 L Psort location Cytoplasmic, score
JOHLMJPM_00087 6.9e-33
JOHLMJPM_00088 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
JOHLMJPM_00089 1.8e-66
JOHLMJPM_00090 6e-149
JOHLMJPM_00091 1.5e-62
JOHLMJPM_00092 3.9e-255 traK U TraM recognition site of TraD and TraG
JOHLMJPM_00093 2.5e-80
JOHLMJPM_00094 8.4e-55 CO COG0526, thiol-disulfide isomerase and thioredoxins
JOHLMJPM_00095 2.5e-88
JOHLMJPM_00096 1.3e-210 M CHAP domain
JOHLMJPM_00097 8.6e-225 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
JOHLMJPM_00098 0.0 U AAA-like domain
JOHLMJPM_00099 4e-116
JOHLMJPM_00100 2.3e-36
JOHLMJPM_00101 8.3e-49 S Cag pathogenicity island, type IV secretory system
JOHLMJPM_00102 3.1e-102
JOHLMJPM_00103 3.8e-48
JOHLMJPM_00104 0.0 L MobA MobL family protein
JOHLMJPM_00105 3.1e-22
JOHLMJPM_00106 1.1e-20
JOHLMJPM_00107 1.8e-189 L Helix-turn-helix domain
JOHLMJPM_00108 4.6e-38 yyaN K MerR HTH family regulatory protein
JOHLMJPM_00109 2e-108 S Domain of unknown function (DUF4811)
JOHLMJPM_00110 7.9e-269 lmrB EGP Major facilitator Superfamily
JOHLMJPM_00111 6.4e-78 merR K MerR HTH family regulatory protein
JOHLMJPM_00112 4.3e-103 K Acetyltransferase (GNAT) domain
JOHLMJPM_00113 3.1e-159 czcD P cation diffusion facilitator family transporter
JOHLMJPM_00114 5.3e-121 sirR K iron dependent repressor
JOHLMJPM_00115 1.6e-121 thrE S Putative threonine/serine exporter
JOHLMJPM_00116 2.2e-73 S Threonine/Serine exporter, ThrE
JOHLMJPM_00117 9.4e-121 lssY 3.6.1.27 I phosphatase
JOHLMJPM_00118 3.2e-152 I alpha/beta hydrolase fold
JOHLMJPM_00119 2.7e-25 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOHLMJPM_00120 6e-277 lysP E amino acid
JOHLMJPM_00121 7.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
JOHLMJPM_00122 5.2e-213 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JOHLMJPM_00131 4.4e-77 ctsR K Belongs to the CtsR family
JOHLMJPM_00132 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
JOHLMJPM_00133 7.7e-106 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00134 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOHLMJPM_00135 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOHLMJPM_00136 1.3e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
JOHLMJPM_00137 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
JOHLMJPM_00138 6.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
JOHLMJPM_00139 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JOHLMJPM_00140 2.7e-236 mepA V MATE efflux family protein
JOHLMJPM_00141 8.9e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
JOHLMJPM_00142 6.1e-117 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JOHLMJPM_00143 3.2e-107 rplD J Forms part of the polypeptide exit tunnel
JOHLMJPM_00144 2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
JOHLMJPM_00145 6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JOHLMJPM_00146 1.8e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JOHLMJPM_00147 2.4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JOHLMJPM_00148 5.1e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JOHLMJPM_00149 7.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JOHLMJPM_00150 4.8e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
JOHLMJPM_00151 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JOHLMJPM_00152 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JOHLMJPM_00153 1.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JOHLMJPM_00154 2.1e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JOHLMJPM_00155 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JOHLMJPM_00156 3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JOHLMJPM_00157 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
JOHLMJPM_00158 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
JOHLMJPM_00159 3.8e-24 rpmD J Ribosomal protein L30
JOHLMJPM_00160 1.9e-69 rplO J Binds to the 23S rRNA
JOHLMJPM_00161 1.2e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
JOHLMJPM_00162 1.1e-124 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
JOHLMJPM_00163 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JOHLMJPM_00164 1.3e-60 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JOHLMJPM_00165 7.5e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JOHLMJPM_00166 9.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JOHLMJPM_00167 7.4e-62 rplQ J Ribosomal protein L17
JOHLMJPM_00168 9.9e-152 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOHLMJPM_00169 8.4e-162 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOHLMJPM_00170 2.7e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
JOHLMJPM_00171 1.3e-153 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
JOHLMJPM_00172 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JOHLMJPM_00173 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
JOHLMJPM_00174 4.4e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
JOHLMJPM_00175 2.2e-241 ktrB P Potassium uptake protein
JOHLMJPM_00176 8.1e-117 ktrA P domain protein
JOHLMJPM_00177 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JOHLMJPM_00178 3.5e-106 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
JOHLMJPM_00179 6.8e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
JOHLMJPM_00180 1.3e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
JOHLMJPM_00181 1.2e-196 asnA 6.3.1.1 F aspartate--ammonia ligase
JOHLMJPM_00182 2.1e-255 yfnA E Amino Acid
JOHLMJPM_00183 1.3e-193 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
JOHLMJPM_00184 9.5e-160 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JOHLMJPM_00185 1.4e-175 L Integrase core domain
JOHLMJPM_00186 2.9e-134 nlhH I alpha/beta hydrolase fold
JOHLMJPM_00187 2e-177 draG 3.2.2.24 O ADP-ribosylglycohydrolase
JOHLMJPM_00188 2.1e-103 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
JOHLMJPM_00190 4.7e-89 cadD P Cadmium resistance transporter
JOHLMJPM_00191 8.3e-78 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
JOHLMJPM_00192 1.7e-77 gtrA S GtrA-like protein
JOHLMJPM_00193 1.8e-306 E Bacterial extracellular solute-binding proteins, family 5 Middle
JOHLMJPM_00194 1.9e-115 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00195 3.5e-233 XK27_06930 S ABC-2 family transporter protein
JOHLMJPM_00196 3.9e-132 qmcA O prohibitin homologues
JOHLMJPM_00197 5.7e-55 S protein encoded in hypervariable junctions of pilus gene clusters
JOHLMJPM_00198 2.1e-134
JOHLMJPM_00199 7.1e-68 GBS0088 S Nucleotidyltransferase
JOHLMJPM_00200 3.7e-85 yybC S Protein of unknown function (DUF2798)
JOHLMJPM_00201 8.9e-57 ydiI Q Thioesterase superfamily
JOHLMJPM_00202 1e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JOHLMJPM_00203 7.8e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
JOHLMJPM_00204 4.2e-95 S Protein of unknown function (DUF1097)
JOHLMJPM_00205 3.4e-169
JOHLMJPM_00206 6.3e-290 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JOHLMJPM_00207 2.2e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
JOHLMJPM_00208 1.7e-213 lmrP E Major Facilitator Superfamily
JOHLMJPM_00211 2.6e-100 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00212 5.4e-181 1.1.1.1 C nadph quinone reductase
JOHLMJPM_00213 8.9e-107 dhaS K Bacterial regulatory proteins, tetR family
JOHLMJPM_00214 2.9e-279 E amino acid
JOHLMJPM_00215 1.2e-285 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
JOHLMJPM_00216 4.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JOHLMJPM_00217 2e-174
JOHLMJPM_00219 5.3e-56 S Protein of unknown function (DUF2975)
JOHLMJPM_00220 3.7e-28 yozG K Transcriptional regulator
JOHLMJPM_00221 1.8e-202
JOHLMJPM_00222 6.3e-100
JOHLMJPM_00223 5.8e-208 ica2 GT2 M Glycosyl transferase family group 2
JOHLMJPM_00224 6.3e-60 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOHLMJPM_00225 8.5e-114 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOHLMJPM_00226 0.0 yhcA V ABC transporter, ATP-binding protein
JOHLMJPM_00227 1.7e-102 bm3R1 K Psort location Cytoplasmic, score
JOHLMJPM_00228 4.5e-70 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOHLMJPM_00229 2.3e-40 S Mor transcription activator family
JOHLMJPM_00230 2.9e-41 S Mor transcription activator family
JOHLMJPM_00231 5.8e-126 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JOHLMJPM_00232 1.4e-19 S Mor transcription activator family
JOHLMJPM_00233 8.6e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
JOHLMJPM_00234 3.4e-198 ybhR V ABC transporter
JOHLMJPM_00235 1.2e-114 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00236 4e-177 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
JOHLMJPM_00237 5.4e-59 yqkB S Belongs to the HesB IscA family
JOHLMJPM_00238 2e-162 yjcE P Sodium proton antiporter
JOHLMJPM_00239 3.9e-19 yjcE P Sodium proton antiporter
JOHLMJPM_00240 1.6e-33 yeaN P Major Facilitator Superfamily
JOHLMJPM_00241 0.0 kup P Transport of potassium into the cell
JOHLMJPM_00242 3.9e-184 C Zinc-binding dehydrogenase
JOHLMJPM_00243 3.1e-18 1.1.1.219 GM Male sterility protein
JOHLMJPM_00244 2.6e-73 1.1.1.219 GM Male sterility protein
JOHLMJPM_00245 3.8e-78 K helix_turn_helix, mercury resistance
JOHLMJPM_00246 7.2e-66 K MarR family
JOHLMJPM_00247 1.1e-49 S Uncharacterized protein conserved in bacteria (DUF2316)
JOHLMJPM_00248 1e-198 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
JOHLMJPM_00249 1.2e-39 K Transcriptional regulator
JOHLMJPM_00250 7.4e-30 K Transcriptional regulator
JOHLMJPM_00251 1.2e-163 akr5f 1.1.1.346 S reductase
JOHLMJPM_00252 4.2e-166 S Oxidoreductase, aldo keto reductase family protein
JOHLMJPM_00253 1e-81
JOHLMJPM_00254 3.9e-215 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JOHLMJPM_00255 3e-153 yitU 3.1.3.104 S hydrolase
JOHLMJPM_00256 1.4e-269 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
JOHLMJPM_00257 2.3e-190 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
JOHLMJPM_00258 6.4e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
JOHLMJPM_00259 1.5e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
JOHLMJPM_00260 2.5e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
JOHLMJPM_00261 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
JOHLMJPM_00262 9e-84 ypmB S Protein conserved in bacteria
JOHLMJPM_00263 2.4e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
JOHLMJPM_00264 5.5e-124 dnaD L Replication initiation and membrane attachment
JOHLMJPM_00265 4.2e-92 yetL K helix_turn_helix multiple antibiotic resistance protein
JOHLMJPM_00266 3.5e-61 P Rhodanese Homology Domain
JOHLMJPM_00267 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
JOHLMJPM_00268 1.4e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
JOHLMJPM_00269 5e-107 ypsA S Belongs to the UPF0398 family
JOHLMJPM_00270 6.4e-28 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
JOHLMJPM_00272 3.6e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
JOHLMJPM_00273 2.3e-68 FG Scavenger mRNA decapping enzyme C-term binding
JOHLMJPM_00274 5.3e-248 amtB P ammonium transporter
JOHLMJPM_00275 4.8e-28
JOHLMJPM_00276 9.7e-84 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
JOHLMJPM_00277 4e-54
JOHLMJPM_00278 2.6e-126 S CAAX protease self-immunity
JOHLMJPM_00279 3.4e-86 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00280 1.6e-111 XK27_02070 S Nitroreductase family
JOHLMJPM_00281 9.9e-208 yurR 1.4.5.1 E FAD dependent oxidoreductase
JOHLMJPM_00282 6.8e-66 rnhA 3.1.26.4 L Ribonuclease HI
JOHLMJPM_00283 2.4e-56 esbA S Family of unknown function (DUF5322)
JOHLMJPM_00284 7.3e-308 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
JOHLMJPM_00285 5.7e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JOHLMJPM_00286 5.5e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOHLMJPM_00287 6.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JOHLMJPM_00288 1.5e-205 carA 6.3.5.5 F Belongs to the CarA family
JOHLMJPM_00289 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
JOHLMJPM_00290 0.0 FbpA K Fibronectin-binding protein
JOHLMJPM_00291 6.3e-70 K Transcriptional regulator
JOHLMJPM_00292 1.3e-198 npp S type I phosphodiesterase nucleotide pyrophosphatase
JOHLMJPM_00293 9e-234 yxiO S Vacuole effluxer Atg22 like
JOHLMJPM_00294 1.3e-159 degV S EDD domain protein, DegV family
JOHLMJPM_00295 3.2e-87 folT S ECF transporter, substrate-specific component
JOHLMJPM_00296 5.1e-75 gtcA S Teichoic acid glycosylation protein
JOHLMJPM_00297 7.7e-26 V VanZ like family
JOHLMJPM_00298 8.5e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JOHLMJPM_00299 9.1e-147 mta K helix_turn_helix, mercury resistance
JOHLMJPM_00300 1.1e-178 C Zinc-binding dehydrogenase
JOHLMJPM_00301 5e-150 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
JOHLMJPM_00302 4.3e-132 Q Methyltransferase domain
JOHLMJPM_00303 2.6e-266
JOHLMJPM_00304 1.6e-199 xerS L Belongs to the 'phage' integrase family
JOHLMJPM_00305 4.6e-76 3.6.1.55 F NUDIX domain
JOHLMJPM_00306 1.9e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOHLMJPM_00307 1.3e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
JOHLMJPM_00308 4.2e-101 zmp1 O PFAM peptidase M10A and M12B, matrixin and adamalysin
JOHLMJPM_00309 3.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
JOHLMJPM_00310 1.6e-182 K Transcriptional regulator
JOHLMJPM_00311 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOHLMJPM_00312 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
JOHLMJPM_00313 1.3e-100 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
JOHLMJPM_00314 1.9e-169 lacX 5.1.3.3 G Aldose 1-epimerase
JOHLMJPM_00315 6.8e-262 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JOHLMJPM_00316 1.8e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JOHLMJPM_00317 5.8e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
JOHLMJPM_00318 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JOHLMJPM_00319 1.8e-167 dprA LU DNA protecting protein DprA
JOHLMJPM_00320 3.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOHLMJPM_00321 1.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JOHLMJPM_00323 4.1e-74 abiGI K Psort location Cytoplasmic, score
JOHLMJPM_00326 1.8e-189 L Helix-turn-helix domain
JOHLMJPM_00327 0.0 ydgH S MMPL family
JOHLMJPM_00328 1.9e-15
JOHLMJPM_00329 4.5e-135 IQ reductase
JOHLMJPM_00330 2.1e-190 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
JOHLMJPM_00331 8.8e-184 S DUF218 domain
JOHLMJPM_00332 6.9e-110 NU mannosyl-glycoprotein
JOHLMJPM_00333 1.1e-245 pbpX1 V SH3-like domain
JOHLMJPM_00334 5.2e-128 terC P integral membrane protein, YkoY family
JOHLMJPM_00335 9.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
JOHLMJPM_00337 3.3e-138 XK27_08845 S ABC transporter, ATP-binding protein
JOHLMJPM_00338 3e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
JOHLMJPM_00339 2.9e-179 XK27_08835 S ABC transporter
JOHLMJPM_00340 9.1e-164 degV S Uncharacterised protein, DegV family COG1307
JOHLMJPM_00341 3.9e-168 XK27_00670 S ABC transporter
JOHLMJPM_00342 7.1e-170 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
JOHLMJPM_00343 5.2e-122 cmpC S ATPases associated with a variety of cellular activities
JOHLMJPM_00344 6.9e-127 XK27_07075 S CAAX protease self-immunity
JOHLMJPM_00345 4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
JOHLMJPM_00346 2.3e-295 S ABC transporter, ATP-binding protein
JOHLMJPM_00347 4.6e-87 M ErfK YbiS YcfS YnhG
JOHLMJPM_00348 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
JOHLMJPM_00349 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
JOHLMJPM_00350 1.2e-242 yfnA E Amino Acid
JOHLMJPM_00351 2.2e-75 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
JOHLMJPM_00352 2.3e-75 gmk2 2.7.4.8 F Guanylate kinase
JOHLMJPM_00353 4.7e-79 zur P Belongs to the Fur family
JOHLMJPM_00354 5.3e-13 3.2.1.14 GH18
JOHLMJPM_00355 6.6e-173
JOHLMJPM_00356 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JOHLMJPM_00357 2.4e-150 glnH ET ABC transporter substrate-binding protein
JOHLMJPM_00358 1.1e-110 gluC P ABC transporter permease
JOHLMJPM_00359 1.6e-109 glnP P ABC transporter permease
JOHLMJPM_00360 1.6e-225 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JOHLMJPM_00361 5.1e-306 oppA E ABC transporter, substratebinding protein
JOHLMJPM_00362 1e-306 oppA E ABC transporter, substratebinding protein
JOHLMJPM_00363 2.2e-152 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOHLMJPM_00364 2.6e-186 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
JOHLMJPM_00365 3.5e-205 oppD P Belongs to the ABC transporter superfamily
JOHLMJPM_00366 4.4e-180 oppF P Belongs to the ABC transporter superfamily
JOHLMJPM_00367 9.1e-121 G phosphoglycerate mutase
JOHLMJPM_00368 2.6e-179 yjbQ P TrkA C-terminal domain protein
JOHLMJPM_00369 9.7e-100 yjbQ P TrkA C-terminal domain protein
JOHLMJPM_00370 0.0 helD 3.6.4.12 L DNA helicase
JOHLMJPM_00371 2.4e-175 coaA 2.7.1.33 F Pantothenic acid kinase
JOHLMJPM_00372 2.9e-102 aacA4_1 4.1.1.17 K acetyltransferase
JOHLMJPM_00373 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
JOHLMJPM_00374 0.0 rafA 3.2.1.22 G alpha-galactosidase
JOHLMJPM_00375 4.3e-73 S Iron-sulphur cluster biosynthesis
JOHLMJPM_00376 0.0 pepN 3.4.11.2 E aminopeptidase
JOHLMJPM_00377 9.6e-264 arcD E Arginine ornithine antiporter
JOHLMJPM_00378 1.8e-278 pipD E Dipeptidase
JOHLMJPM_00379 9e-96 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
JOHLMJPM_00380 7.3e-71 K Transcriptional regulator
JOHLMJPM_00381 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
JOHLMJPM_00382 1.9e-299 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JOHLMJPM_00383 4e-237 lacY G Oligosaccharide H symporter
JOHLMJPM_00384 1.2e-201 abf G Belongs to the glycosyl hydrolase 43 family
JOHLMJPM_00385 1.9e-74 L Transposase and inactivated derivatives, IS30 family
JOHLMJPM_00387 3e-98 I NUDIX domain
JOHLMJPM_00388 2.8e-114 yviA S Protein of unknown function (DUF421)
JOHLMJPM_00389 4.4e-74 S Protein of unknown function (DUF3290)
JOHLMJPM_00390 6.7e-167 ropB K Helix-turn-helix XRE-family like proteins
JOHLMJPM_00391 8.8e-221 EGP Major facilitator Superfamily
JOHLMJPM_00392 9.8e-255 gshR 1.8.1.7 C Glutathione reductase
JOHLMJPM_00393 9.1e-36 ygbF S Sugar efflux transporter for intercellular exchange
JOHLMJPM_00395 7.5e-198 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
JOHLMJPM_00396 1e-35
JOHLMJPM_00397 1.5e-138 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
JOHLMJPM_00398 1.3e-233 gntT EG Citrate transporter
JOHLMJPM_00399 3.7e-179 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
JOHLMJPM_00400 3.8e-108 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase HUMPS family
JOHLMJPM_00401 1.3e-88 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
JOHLMJPM_00402 1.9e-167 kdgR K helix_turn _helix lactose operon repressor
JOHLMJPM_00403 4.3e-55
JOHLMJPM_00404 8.2e-84
JOHLMJPM_00405 0.0 helD 3.6.4.12 L DNA helicase
JOHLMJPM_00406 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOHLMJPM_00407 5.7e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JOHLMJPM_00408 1.3e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
JOHLMJPM_00409 4.9e-179
JOHLMJPM_00410 1.8e-130 cobB K SIR2 family
JOHLMJPM_00411 3.8e-51
JOHLMJPM_00412 2.1e-162 yunF F Protein of unknown function DUF72
JOHLMJPM_00413 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JOHLMJPM_00414 1.8e-147 tatD L hydrolase, TatD family
JOHLMJPM_00415 4.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
JOHLMJPM_00416 1.3e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
JOHLMJPM_00417 4.3e-36 veg S Biofilm formation stimulator VEG
JOHLMJPM_00418 1.9e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JOHLMJPM_00419 8.4e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
JOHLMJPM_00420 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
JOHLMJPM_00421 2.8e-260 xylP G MFS/sugar transport protein
JOHLMJPM_00422 3.1e-212 xylR GK ROK family
JOHLMJPM_00423 1.3e-295 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
JOHLMJPM_00424 1.4e-167 2.7.1.2 GK ROK family
JOHLMJPM_00425 7.4e-91
JOHLMJPM_00427 2.2e-158 S Prolyl oligopeptidase family
JOHLMJPM_00428 3.6e-171 znuA P Belongs to the bacterial solute-binding protein 9 family
JOHLMJPM_00429 2.7e-131 fhuC P ABC transporter
JOHLMJPM_00430 8.2e-132 znuB U ABC 3 transport family
JOHLMJPM_00432 1.8e-145 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
JOHLMJPM_00433 1.3e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JOHLMJPM_00434 5.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOHLMJPM_00435 9.7e-56 S Domain of unknown function (DUF3899)
JOHLMJPM_00436 2.5e-71 racA K helix_turn_helix, mercury resistance
JOHLMJPM_00437 5.8e-132 gntR K UbiC transcription regulator-associated domain protein
JOHLMJPM_00438 0.0 xpkA 4.1.2.22, 4.1.2.9 G Phosphoketolase
JOHLMJPM_00439 4.6e-146 yxeH S hydrolase
JOHLMJPM_00440 1.3e-267 ywfO S HD domain protein
JOHLMJPM_00441 4.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
JOHLMJPM_00442 1.7e-78 ywiB S Domain of unknown function (DUF1934)
JOHLMJPM_00443 5.8e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
JOHLMJPM_00444 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
JOHLMJPM_00445 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
JOHLMJPM_00446 1.1e-245
JOHLMJPM_00447 2.7e-73 K Transcriptional regulator
JOHLMJPM_00448 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
JOHLMJPM_00449 4e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
JOHLMJPM_00450 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
JOHLMJPM_00451 1.1e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOHLMJPM_00452 4.3e-42 rpmE2 J Ribosomal protein L31
JOHLMJPM_00453 8.7e-117 srtA 3.4.22.70 M sortase family
JOHLMJPM_00454 5.6e-252 XK27_00720 S Leucine-rich repeat (LRR) protein
JOHLMJPM_00455 5.3e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JOHLMJPM_00456 9.9e-95 lemA S LemA family
JOHLMJPM_00457 1.6e-147 htpX O Belongs to the peptidase M48B family
JOHLMJPM_00458 8.6e-150
JOHLMJPM_00459 2.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
JOHLMJPM_00460 1.6e-240 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
JOHLMJPM_00461 7.2e-214 S nuclear-transcribed mRNA catabolic process, no-go decay
JOHLMJPM_00462 2.9e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
JOHLMJPM_00463 1.4e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JOHLMJPM_00465 3.6e-61 ndoA L Toxic component of a toxin-antitoxin (TA) module
JOHLMJPM_00466 1.1e-113 S (CBS) domain
JOHLMJPM_00468 1.9e-256 S Putative peptidoglycan binding domain
JOHLMJPM_00469 2.2e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
JOHLMJPM_00470 8.7e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
JOHLMJPM_00471 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JOHLMJPM_00472 1.4e-295 yabM S Polysaccharide biosynthesis protein
JOHLMJPM_00473 1.6e-39 yabO J S4 domain protein
JOHLMJPM_00474 9.7e-44 divIC D Septum formation initiator
JOHLMJPM_00475 3.9e-237 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
JOHLMJPM_00476 4.2e-71 yabR J RNA binding
JOHLMJPM_00477 5.1e-259 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
JOHLMJPM_00478 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
JOHLMJPM_00479 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JOHLMJPM_00480 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JOHLMJPM_00481 7.9e-196 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOHLMJPM_00482 2.9e-185 L Transposase
JOHLMJPM_00483 2.3e-49
JOHLMJPM_00484 5.3e-169 C Aldo keto reductase
JOHLMJPM_00485 7.5e-70
JOHLMJPM_00486 7e-95 Z012_06855 S Acetyltransferase (GNAT) family
JOHLMJPM_00487 7.6e-253 nhaC C Na H antiporter NhaC
JOHLMJPM_00488 2.3e-190 S Membrane transport protein
JOHLMJPM_00489 7e-189 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOHLMJPM_00490 7.6e-278 yufL 2.7.13.3 T Single cache domain 3
JOHLMJPM_00491 3e-125 malR3 K cheY-homologous receiver domain
JOHLMJPM_00492 2e-178 S ABC-2 family transporter protein
JOHLMJPM_00493 1.4e-101 XK27_06935 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00494 1.8e-124 yliE T Putative diguanylate phosphodiesterase
JOHLMJPM_00495 6.9e-95 wecD K Acetyltransferase (GNAT) family
JOHLMJPM_00496 3.1e-140 S zinc-ribbon domain
JOHLMJPM_00497 1.6e-234 S response to antibiotic
JOHLMJPM_00499 1.2e-85 F NUDIX domain
JOHLMJPM_00501 8.3e-104 padC Q Phenolic acid decarboxylase
JOHLMJPM_00502 1.8e-83 padR K Virulence activator alpha C-term
JOHLMJPM_00503 5.3e-101 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00504 1.4e-187 1.1.1.219 GM Male sterility protein
JOHLMJPM_00505 1.2e-76 elaA S Gnat family
JOHLMJPM_00506 2.1e-79 yybA 2.3.1.57 K Transcriptional regulator
JOHLMJPM_00507 1.2e-73
JOHLMJPM_00508 3.3e-23
JOHLMJPM_00509 4.1e-61
JOHLMJPM_00510 5e-91 P Cadmium resistance transporter
JOHLMJPM_00511 3.1e-121 sirR K Helix-turn-helix diphteria tox regulatory element
JOHLMJPM_00512 1.3e-70 T Universal stress protein family
JOHLMJPM_00513 2.4e-284 mntH P H( )-stimulated, divalent metal cation uptake system
JOHLMJPM_00514 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JOHLMJPM_00515 3.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JOHLMJPM_00516 2.2e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JOHLMJPM_00517 6.1e-97 fadR K Bacterial regulatory proteins, tetR family
JOHLMJPM_00518 3.9e-181 D Alpha beta
JOHLMJPM_00519 1.1e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
JOHLMJPM_00520 5.7e-166 I Alpha beta
JOHLMJPM_00521 0.0 O Pro-kumamolisin, activation domain
JOHLMJPM_00522 1.3e-119 S Membrane
JOHLMJPM_00523 6.2e-134 puuD S peptidase C26
JOHLMJPM_00524 3.7e-38
JOHLMJPM_00525 2.8e-114 magIII L Base excision DNA repair protein, HhH-GPD family
JOHLMJPM_00526 1.4e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JOHLMJPM_00527 3.2e-200 M NlpC/P60 family
JOHLMJPM_00528 1.5e-163 G Peptidase_C39 like family
JOHLMJPM_00529 4.5e-105 pncA Q Isochorismatase family
JOHLMJPM_00530 1.5e-55 K Transcriptional regulator PadR-like family
JOHLMJPM_00531 6.3e-74 XK27_06920 S Protein of unknown function (DUF1700)
JOHLMJPM_00532 4.4e-119 S Putative adhesin
JOHLMJPM_00533 2.7e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JOHLMJPM_00534 7.8e-227 fabV 1.3.1.44, 1.3.1.9 I NAD(P)H binding domain of trans-2-enoyl-CoA reductase
JOHLMJPM_00535 7.4e-74 fld C Flavodoxin
JOHLMJPM_00536 3.9e-98 K Acetyltransferase (GNAT) domain
JOHLMJPM_00537 8.7e-243 yifK E Amino acid permease
JOHLMJPM_00538 1.1e-118
JOHLMJPM_00539 5.5e-104 S WxL domain surface cell wall-binding
JOHLMJPM_00540 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
JOHLMJPM_00541 1.9e-228 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JOHLMJPM_00542 1.2e-188 adhP 1.1.1.1 C alcohol dehydrogenase
JOHLMJPM_00543 1.4e-69 lrpA K AsnC family
JOHLMJPM_00544 1.5e-169 opuBA E ABC transporter, ATP-binding protein
JOHLMJPM_00545 7.5e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JOHLMJPM_00546 8.1e-202 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
JOHLMJPM_00547 2.6e-100 S NADPH-dependent FMN reductase
JOHLMJPM_00548 9.2e-73 K MarR family
JOHLMJPM_00549 0.0 pacL1 P P-type ATPase
JOHLMJPM_00551 2.3e-278 pipD E Dipeptidase
JOHLMJPM_00552 3.3e-155
JOHLMJPM_00553 5.4e-101 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
JOHLMJPM_00554 1.3e-119 S Elongation factor G-binding protein, N-terminal
JOHLMJPM_00555 4e-170 EG EamA-like transporter family
JOHLMJPM_00556 0.0 copB 3.6.3.4 P P-type ATPase
JOHLMJPM_00557 1.7e-78 copR K Copper transport repressor CopY TcrY
JOHLMJPM_00558 6.3e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JOHLMJPM_00559 1.7e-159 S reductase
JOHLMJPM_00560 0.0 ctpA 3.6.3.54 P P-type ATPase
JOHLMJPM_00561 2.5e-67 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
JOHLMJPM_00563 9.3e-158 yxkH G Polysaccharide deacetylase
JOHLMJPM_00564 1.6e-159 xerD L Phage integrase, N-terminal SAM-like domain
JOHLMJPM_00565 4.2e-192 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JOHLMJPM_00566 0.0 oatA I Acyltransferase
JOHLMJPM_00567 7.8e-124
JOHLMJPM_00568 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
JOHLMJPM_00569 2.6e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JOHLMJPM_00570 1.3e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
JOHLMJPM_00571 3.6e-38
JOHLMJPM_00572 2.4e-94 K helix_turn_helix multiple antibiotic resistance protein
JOHLMJPM_00573 8.1e-249 xylP1 G MFS/sugar transport protein
JOHLMJPM_00574 4.6e-99 S Protein of unknown function (DUF1440)
JOHLMJPM_00575 0.0 uvrA2 L ABC transporter
JOHLMJPM_00576 5e-66 S Tautomerase enzyme
JOHLMJPM_00577 3.2e-265
JOHLMJPM_00578 3.8e-222
JOHLMJPM_00579 2.1e-109 opuCD P Binding-protein-dependent transport system inner membrane component
JOHLMJPM_00580 2e-177 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
JOHLMJPM_00581 8e-106 opuCB E ABC transporter permease
JOHLMJPM_00582 2.8e-224 opuCA E ABC transporter, ATP-binding protein
JOHLMJPM_00583 2.1e-45
JOHLMJPM_00584 9.2e-223 mdtG EGP Major facilitator Superfamily
JOHLMJPM_00585 2.5e-183 yfeX P Peroxidase
JOHLMJPM_00586 3.6e-229 patB 4.4.1.8 E Aminotransferase, class I
JOHLMJPM_00587 5.6e-110 M Protein of unknown function (DUF3737)
JOHLMJPM_00588 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JOHLMJPM_00589 7.4e-194 ykoT GT2 M Glycosyl transferase family 2
JOHLMJPM_00590 1.4e-248 M hydrolase, family 25
JOHLMJPM_00591 3.3e-107
JOHLMJPM_00592 3.1e-196 yubA S AI-2E family transporter
JOHLMJPM_00593 7.5e-171 yclI V FtsX-like permease family
JOHLMJPM_00594 8.3e-122 yclH V ABC transporter
JOHLMJPM_00595 0.0 malL 3.2.1.10, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G Alpha amylase, catalytic domain protein
JOHLMJPM_00596 8.6e-57 K Winged helix DNA-binding domain
JOHLMJPM_00597 1.1e-138 pnuC H nicotinamide mononucleotide transporter
JOHLMJPM_00598 8.2e-152 corA P CorA-like Mg2+ transporter protein
JOHLMJPM_00599 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
JOHLMJPM_00600 4.1e-66
JOHLMJPM_00601 6.5e-43
JOHLMJPM_00602 1.8e-248 T PhoQ Sensor
JOHLMJPM_00603 8e-131 K Transcriptional regulatory protein, C terminal
JOHLMJPM_00604 2.3e-34
JOHLMJPM_00605 1.9e-115 ylbE GM NAD(P)H-binding
JOHLMJPM_00606 6.5e-229 ndh 1.6.99.3 C NADH dehydrogenase
JOHLMJPM_00607 8.1e-96 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JOHLMJPM_00608 1.4e-175 L Integrase core domain
JOHLMJPM_00609 1.4e-175 L Integrase core domain
JOHLMJPM_00610 4e-96 tnpR1 L Resolvase, N terminal domain
JOHLMJPM_00611 2.1e-58 S Family of unknown function (DUF5388)
JOHLMJPM_00612 2.7e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
JOHLMJPM_00614 1.4e-220 L Transposase
JOHLMJPM_00615 1.8e-139 IQ reductase
JOHLMJPM_00618 3.1e-56 tnp2PF3 L Transposase DDE domain
JOHLMJPM_00619 1e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
JOHLMJPM_00620 5.6e-43 relB L Addiction module antitoxin, RelB DinJ family
JOHLMJPM_00621 9.7e-86
JOHLMJPM_00622 7.5e-40
JOHLMJPM_00623 5.5e-27
JOHLMJPM_00624 0.0 traA L MobA MobL family protein
JOHLMJPM_00625 4.8e-194 L Psort location Cytoplasmic, score
JOHLMJPM_00626 2.4e-84 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
JOHLMJPM_00627 1.1e-305 hsdM 2.1.1.72 V type I restriction-modification system
JOHLMJPM_00628 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
JOHLMJPM_00629 5.4e-32 L Putative transposase of IS4/5 family (DUF4096)
JOHLMJPM_00630 6.9e-124 L Transposase and inactivated derivatives, IS30 family
JOHLMJPM_00632 8.9e-127 tnp L DDE domain
JOHLMJPM_00633 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
JOHLMJPM_00634 1.1e-240 gshR1 1.8.1.7 C Glutathione reductase
JOHLMJPM_00635 4.3e-52
JOHLMJPM_00636 3.5e-174 L Transposase and inactivated derivatives, IS30 family
JOHLMJPM_00637 1e-217 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
JOHLMJPM_00638 2e-147 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
JOHLMJPM_00639 2.1e-56 M LysM domain protein
JOHLMJPM_00641 6.5e-57 M LysM domain
JOHLMJPM_00643 2.7e-97 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00644 1.7e-167 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JOHLMJPM_00645 1.9e-178 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
JOHLMJPM_00646 1.6e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOHLMJPM_00647 1.1e-57 DR0488 S 3D domain
JOHLMJPM_00648 2.2e-288 M Exporter of polyketide antibiotics
JOHLMJPM_00649 4.2e-169 yjjC V ABC transporter
JOHLMJPM_00650 8.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
JOHLMJPM_00651 3.6e-249 V Polysaccharide biosynthesis C-terminal domain
JOHLMJPM_00652 2.9e-289 uxaC 5.3.1.12 G glucuronate isomerase
JOHLMJPM_00653 1.4e-259 gph G MFS/sugar transport protein
JOHLMJPM_00654 0.0 yicI 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
JOHLMJPM_00655 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
JOHLMJPM_00656 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
JOHLMJPM_00657 1.4e-169 yqhA G Aldose 1-epimerase
JOHLMJPM_00658 3.2e-121 pgm3 G Belongs to the phosphoglycerate mutase family
JOHLMJPM_00659 1.4e-189 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOHLMJPM_00660 2.7e-304 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
JOHLMJPM_00661 2.3e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
JOHLMJPM_00662 2.6e-129 kdgR K FCD domain
JOHLMJPM_00663 8.8e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
JOHLMJPM_00664 2.4e-184 exuR K Periplasmic binding protein domain
JOHLMJPM_00665 4.9e-279 yjmB G MFS/sugar transport protein
JOHLMJPM_00666 4.8e-309 5.1.2.7 S tagaturonate epimerase
JOHLMJPM_00667 4e-294 uxaC 5.3.1.12 G glucuronate isomerase
JOHLMJPM_00668 1.5e-233 S module of peptide synthetase
JOHLMJPM_00670 3.3e-253 EGP Major facilitator Superfamily
JOHLMJPM_00671 1e-16 S Protein of unknown function (DUF3278)
JOHLMJPM_00672 9.7e-15 U Bacterial surface protein 26-residue
JOHLMJPM_00673 1.2e-130
JOHLMJPM_00674 9.9e-91 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JOHLMJPM_00675 2e-132 gntR1 K UbiC transcription regulator-associated domain protein
JOHLMJPM_00676 8.2e-125 O Zinc-dependent metalloprotease
JOHLMJPM_00677 3.9e-84 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JOHLMJPM_00678 1.8e-77
JOHLMJPM_00679 9.2e-141 plnC K LytTr DNA-binding domain
JOHLMJPM_00680 6.2e-241 2.7.13.3 T GHKL domain
JOHLMJPM_00681 5.2e-240 2.1.1.80, 2.7.13.3, 3.1.1.61 T protein histidine kinase activity
JOHLMJPM_00682 1.4e-133 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
JOHLMJPM_00684 2.5e-174 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
JOHLMJPM_00685 1.1e-77 uspA T universal stress protein
JOHLMJPM_00686 1.6e-90 norB EGP Major Facilitator
JOHLMJPM_00687 6.1e-72 norB EGP Major Facilitator
JOHLMJPM_00688 1.7e-11 K transcriptional regulator
JOHLMJPM_00689 2.6e-46 K transcriptional regulator
JOHLMJPM_00690 0.0 oppA1 E ABC transporter substrate-binding protein
JOHLMJPM_00691 1e-173 oppC EP Binding-protein-dependent transport system inner membrane component
JOHLMJPM_00692 9.8e-180 oppB P ABC transporter permease
JOHLMJPM_00693 1.3e-179 oppF P Belongs to the ABC transporter superfamily
JOHLMJPM_00694 2.4e-192 oppD P Belongs to the ABC transporter superfamily
JOHLMJPM_00695 3.9e-81 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
JOHLMJPM_00696 1.6e-196 lplA 6.3.1.20 H Lipoate-protein ligase
JOHLMJPM_00697 2.3e-69
JOHLMJPM_00698 2e-48
JOHLMJPM_00699 1.8e-189 L Helix-turn-helix domain
JOHLMJPM_00700 1.4e-175 L Integrase core domain
JOHLMJPM_00701 6.6e-240 3.1.3.48 T Tyrosine phosphatase family
JOHLMJPM_00702 1.6e-182 pdxB EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
JOHLMJPM_00703 9.3e-283 cydA 1.10.3.14 C ubiquinol oxidase
JOHLMJPM_00704 1.1e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
JOHLMJPM_00705 1.8e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
JOHLMJPM_00706 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JOHLMJPM_00707 2.8e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JOHLMJPM_00708 2e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
JOHLMJPM_00709 5.1e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
JOHLMJPM_00710 8.6e-215 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JOHLMJPM_00711 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
JOHLMJPM_00712 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JOHLMJPM_00713 1.1e-193 camS S sex pheromone
JOHLMJPM_00714 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOHLMJPM_00715 3.8e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
JOHLMJPM_00716 6.5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JOHLMJPM_00717 9.4e-189 yegS 2.7.1.107 G Lipid kinase
JOHLMJPM_00718 1e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOHLMJPM_00719 2.1e-165 mod 2.1.1.72, 3.1.21.5 L DNA methylase
JOHLMJPM_00720 1.4e-175 L Integrase core domain
JOHLMJPM_00721 3.4e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
JOHLMJPM_00722 1e-107 ahpC 1.11.1.15 O Peroxiredoxin
JOHLMJPM_00723 4.8e-60
JOHLMJPM_00724 8.1e-114 ylbE GM NAD(P)H-binding
JOHLMJPM_00725 1.1e-45
JOHLMJPM_00726 6.6e-17 K Helix-turn-helix XRE-family like proteins
JOHLMJPM_00727 3.2e-47 K Helix-turn-helix XRE-family like proteins
JOHLMJPM_00730 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JOHLMJPM_00731 1e-72 K Transcriptional regulator
JOHLMJPM_00732 4.2e-77 elaA S Gnat family
JOHLMJPM_00733 6.2e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JOHLMJPM_00734 2.5e-160 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
JOHLMJPM_00735 2.2e-159 1.1.1.65 C Aldo keto reductase
JOHLMJPM_00736 3e-89
JOHLMJPM_00737 6e-216 yttB EGP Major facilitator Superfamily
JOHLMJPM_00738 4.9e-246 glpT G Major Facilitator Superfamily
JOHLMJPM_00739 5.2e-136 nfrA 1.5.1.39 C nitroreductase
JOHLMJPM_00740 5.3e-86 nrdI F Belongs to the NrdI family
JOHLMJPM_00741 1.2e-269 S ATPases associated with a variety of cellular activities
JOHLMJPM_00742 2.4e-251 lmrB EGP Major facilitator Superfamily
JOHLMJPM_00744 2e-143 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
JOHLMJPM_00745 1.9e-175 K Transcriptional regulator, LacI family
JOHLMJPM_00746 3.3e-242 yhdP S Transporter associated domain
JOHLMJPM_00747 7.6e-61
JOHLMJPM_00748 1.4e-74 hsp O Belongs to the small heat shock protein (HSP20) family
JOHLMJPM_00749 3.2e-262 yjeM E Amino Acid
JOHLMJPM_00750 3.6e-162 ytbE 1.1.1.346 S Aldo keto reductase
JOHLMJPM_00752 0.0 yfgQ P E1-E2 ATPase
JOHLMJPM_00753 2.2e-93 M1-874 K Domain of unknown function (DUF1836)
JOHLMJPM_00754 0.0 glpQ 3.1.4.46 C phosphodiesterase
JOHLMJPM_00755 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
JOHLMJPM_00756 6.1e-52 M LysM domain protein
JOHLMJPM_00757 9.5e-74
JOHLMJPM_00758 4.1e-27 K Transcriptional
JOHLMJPM_00759 2.7e-224 LO Uncharacterized conserved protein (DUF2075)
JOHLMJPM_00760 4.9e-119 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
JOHLMJPM_00761 1.5e-25
JOHLMJPM_00762 7.2e-81
JOHLMJPM_00763 2e-92 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
JOHLMJPM_00764 4.2e-209 pmrB EGP Major facilitator Superfamily
JOHLMJPM_00765 1.6e-73 S COG NOG18757 non supervised orthologous group
JOHLMJPM_00766 6.8e-98 K Bacterial regulatory proteins, tetR family
JOHLMJPM_00767 9.7e-138 IQ reductase
JOHLMJPM_00768 8.7e-234 EK Aminotransferase, class I
JOHLMJPM_00769 0.0 tetP J elongation factor G
JOHLMJPM_00770 4.5e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
JOHLMJPM_00771 1.5e-166 yhaZ L DNA alkylation repair enzyme
JOHLMJPM_00772 2.3e-122 yihL K UTRA
JOHLMJPM_00773 2.6e-191 yegU O ADP-ribosylglycohydrolase
JOHLMJPM_00774 1.3e-257 F Belongs to the purine-cytosine permease (2.A.39) family
JOHLMJPM_00775 2.1e-165 G Belongs to the carbohydrate kinase PfkB family
JOHLMJPM_00776 7.3e-177 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
JOHLMJPM_00777 6.5e-136 S Protein of unknown function
JOHLMJPM_00778 7.5e-217 naiP EGP Major facilitator Superfamily
JOHLMJPM_00779 5.3e-122 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JOHLMJPM_00780 7.6e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JOHLMJPM_00781 3.2e-138 S Belongs to the UPF0246 family
JOHLMJPM_00782 8.8e-308 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
JOHLMJPM_00783 1.2e-157 K Transcriptional regulator
JOHLMJPM_00784 7.8e-14 yjdF S Protein of unknown function (DUF2992)
JOHLMJPM_00785 6.4e-14 S Transglycosylase associated protein
JOHLMJPM_00786 3.6e-39
JOHLMJPM_00787 1.5e-304 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JOHLMJPM_00788 6.3e-157 EG EamA-like transporter family
JOHLMJPM_00789 1.9e-26
JOHLMJPM_00790 2.7e-208 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
JOHLMJPM_00793 1.3e-38
JOHLMJPM_00794 2.2e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOHLMJPM_00795 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
JOHLMJPM_00796 6.8e-262 E Amino acid permease
JOHLMJPM_00797 8.1e-239 nhaC C Na H antiporter NhaC
JOHLMJPM_00798 6.6e-198 ptcA 2.1.3.3, 2.1.3.6 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOHLMJPM_00799 2e-234 aguD E Amino Acid
JOHLMJPM_00800 1e-217 aguA 3.5.3.12 E agmatine deiminase
JOHLMJPM_00801 4.5e-169 arcC 2.7.2.2 E Belongs to the carbamate kinase family
JOHLMJPM_00802 2.8e-139 K Helix-turn-helix domain, rpiR family
JOHLMJPM_00803 1.7e-162 mleR K LysR family
JOHLMJPM_00804 1e-309 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
JOHLMJPM_00805 1.5e-167 mleP S Sodium Bile acid symporter family
JOHLMJPM_00806 4e-84 thiW S Thiamine-precursor transporter protein (ThiW)
JOHLMJPM_00807 6.8e-207 ynfM EGP Major facilitator Superfamily
JOHLMJPM_00808 2.4e-87 ygfC K Bacterial regulatory proteins, tetR family
JOHLMJPM_00809 2.6e-181 hrtB V ABC transporter permease
JOHLMJPM_00810 7.8e-123 devA 3.6.3.25 V ABC transporter, ATP-binding protein
JOHLMJPM_00811 9.2e-224 EGP Major facilitator Superfamily
JOHLMJPM_00812 2.1e-99 S Phosphatidylethanolamine-binding protein
JOHLMJPM_00813 3.7e-69 ycgX S Protein of unknown function (DUF1398)
JOHLMJPM_00814 2.8e-122 S GyrI-like small molecule binding domain
JOHLMJPM_00815 1.8e-135 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
JOHLMJPM_00816 6.3e-221 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
JOHLMJPM_00817 3.1e-173 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JOHLMJPM_00818 8.9e-119 yeiL K Cyclic nucleotide-monophosphate binding domain
JOHLMJPM_00819 2.8e-179 rihB 3.2.2.1, 3.2.2.8 F Nucleoside
JOHLMJPM_00820 1.4e-214 mccF V LD-carboxypeptidase
JOHLMJPM_00821 1.2e-67 K Transcriptional regulator, HxlR family
JOHLMJPM_00822 3.1e-12
JOHLMJPM_00823 1.2e-224 C Oxidoreductase
JOHLMJPM_00824 2.7e-51 K helix_turn_helix, mercury resistance
JOHLMJPM_00825 3.6e-117
JOHLMJPM_00826 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
JOHLMJPM_00827 3e-262 G Major Facilitator
JOHLMJPM_00828 2.5e-178 K Transcriptional regulator, LacI family
JOHLMJPM_00829 2.3e-07
JOHLMJPM_00830 6.8e-84
JOHLMJPM_00831 7.7e-310 E ABC transporter, substratebinding protein
JOHLMJPM_00832 1.7e-173 K transcriptional regulator, ArsR family
JOHLMJPM_00833 2.3e-102 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
JOHLMJPM_00834 5.1e-201 araR K Transcriptional regulator
JOHLMJPM_00835 1.8e-254 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
JOHLMJPM_00836 3.2e-308 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
JOHLMJPM_00837 3.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
JOHLMJPM_00838 1e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
JOHLMJPM_00839 1.5e-90 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
JOHLMJPM_00842 4e-53 S Glycine cleavage H-protein
JOHLMJPM_00843 3e-167 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
JOHLMJPM_00844 7.2e-141 yejC S Protein of unknown function (DUF1003)
JOHLMJPM_00845 3.7e-105 3.2.2.20 K acetyltransferase
JOHLMJPM_00846 3.8e-87 nimA S resistance protein
JOHLMJPM_00847 6e-91 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
JOHLMJPM_00848 2.6e-70
JOHLMJPM_00849 2.4e-220 EGP Major facilitator Superfamily
JOHLMJPM_00850 4.1e-234 pyrP F Permease
JOHLMJPM_00851 4.3e-50 azlD S Branched-chain amino acid transport protein (AzlD)
JOHLMJPM_00852 7.5e-98 azlC E branched-chain amino acid
JOHLMJPM_00853 1.4e-189 L Helix-turn-helix domain
JOHLMJPM_00854 9.1e-175 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHLMJPM_00855 1.2e-185 2.7.7.65 T diguanylate cyclase
JOHLMJPM_00856 7.6e-178 K AI-2E family transporter
JOHLMJPM_00857 2.5e-155 manN G system, mannose fructose sorbose family IID component
JOHLMJPM_00858 1.1e-117 manM G PTS system
JOHLMJPM_00859 6.9e-60 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
JOHLMJPM_00860 4.3e-55 manL 2.7.1.191 G PTS system fructose IIA component
JOHLMJPM_00861 1.8e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant
JOHLMJPM_00862 3e-246 dinF V MatE
JOHLMJPM_00863 6.6e-75 K MarR family
JOHLMJPM_00864 1.6e-100 S Psort location CytoplasmicMembrane, score
JOHLMJPM_00865 5.5e-18 yobS K transcriptional regulator
JOHLMJPM_00866 3.1e-47 4.1.1.52, 4.2.1.83 E amidohydrolase
JOHLMJPM_00868 3.7e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
JOHLMJPM_00869 4e-89 ydcK S Belongs to the SprT family
JOHLMJPM_00870 0.0 yhgF K Tex-like protein N-terminal domain protein
JOHLMJPM_00871 1.4e-72
JOHLMJPM_00872 1.6e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
JOHLMJPM_00873 4.8e-287 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JOHLMJPM_00874 5.3e-141 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
JOHLMJPM_00875 2.3e-95 MA20_25245 K FR47-like protein
JOHLMJPM_00876 1.9e-124 gntR1 K UbiC transcription regulator-associated domain protein
JOHLMJPM_00877 1.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
JOHLMJPM_00878 6.6e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JOHLMJPM_00881 7.7e-151 yjjH S Calcineurin-like phosphoesterase
JOHLMJPM_00882 1.3e-298 dtpT U amino acid peptide transporter
JOHLMJPM_00883 1.7e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
JOHLMJPM_00886 9.1e-175 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHLMJPM_00887 1.8e-259 dapE 3.5.1.18 E Peptidase dimerisation domain
JOHLMJPM_00888 1.3e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
JOHLMJPM_00889 4.1e-89
JOHLMJPM_00890 2e-56 ypaA S Protein of unknown function (DUF1304)
JOHLMJPM_00892 8.3e-24
JOHLMJPM_00893 2.7e-79 O OsmC-like protein
JOHLMJPM_00894 1.9e-25
JOHLMJPM_00895 2.3e-75 K Transcriptional regulator
JOHLMJPM_00896 2.9e-78 S Domain of unknown function (DUF5067)
JOHLMJPM_00897 4.3e-152 licD M LicD family
JOHLMJPM_00898 6.4e-290 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JOHLMJPM_00899 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JOHLMJPM_00900 2.4e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
JOHLMJPM_00901 7.1e-141 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
JOHLMJPM_00902 9.9e-172 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JOHLMJPM_00903 1.2e-163 isdE P Periplasmic binding protein
JOHLMJPM_00904 5.2e-91 M Iron Transport-associated domain
JOHLMJPM_00905 1.8e-178 M Iron Transport-associated domain
JOHLMJPM_00906 1.8e-88 S Iron Transport-associated domain
JOHLMJPM_00907 6.2e-51
JOHLMJPM_00908 7.9e-202 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
JOHLMJPM_00909 1.1e-25 copZ P Heavy-metal-associated domain
JOHLMJPM_00910 1.1e-98 dps P Belongs to the Dps family
JOHLMJPM_00911 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
JOHLMJPM_00912 5.2e-254 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
JOHLMJPM_00913 9.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
JOHLMJPM_00914 1.7e-12
JOHLMJPM_00915 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
JOHLMJPM_00916 1.1e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JOHLMJPM_00917 4.3e-135 ybbR S YbbR-like protein
JOHLMJPM_00918 4.5e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JOHLMJPM_00919 1.2e-123 S Protein of unknown function (DUF1361)
JOHLMJPM_00920 0.0 yjcE P Sodium proton antiporter
JOHLMJPM_00921 5e-165 murB 1.3.1.98 M Cell wall formation
JOHLMJPM_00922 2.4e-152 xth 3.1.11.2 L exodeoxyribonuclease III
JOHLMJPM_00923 6e-102 dnaQ 2.7.7.7 L DNA polymerase III
JOHLMJPM_00924 3e-195 C Aldo keto reductase family protein
JOHLMJPM_00925 1.4e-87 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
JOHLMJPM_00926 1.1e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
JOHLMJPM_00927 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
JOHLMJPM_00928 1.8e-141 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JOHLMJPM_00929 4.4e-103 yxjI
JOHLMJPM_00930 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JOHLMJPM_00931 2.3e-81 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
JOHLMJPM_00932 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
JOHLMJPM_00933 7.1e-141 est 3.1.1.1 S Serine aminopeptidase, S33
JOHLMJPM_00934 4.9e-32 secG U Preprotein translocase
JOHLMJPM_00935 3.9e-287 clcA P chloride
JOHLMJPM_00937 6.1e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
JOHLMJPM_00938 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
JOHLMJPM_00939 4.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
JOHLMJPM_00940 9e-192 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
JOHLMJPM_00941 7.5e-186 cggR K Putative sugar-binding domain
JOHLMJPM_00943 1.4e-107 S ECF transporter, substrate-specific component
JOHLMJPM_00945 1.6e-126 liaI S membrane
JOHLMJPM_00946 2.6e-74 XK27_02470 K LytTr DNA-binding domain
JOHLMJPM_00947 1.7e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
JOHLMJPM_00948 9.9e-169 whiA K May be required for sporulation
JOHLMJPM_00949 3.4e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
JOHLMJPM_00950 4.8e-165 rapZ S Displays ATPase and GTPase activities
JOHLMJPM_00951 2.4e-90 S Short repeat of unknown function (DUF308)
JOHLMJPM_00952 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
JOHLMJPM_00953 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
JOHLMJPM_00954 1.5e-94 K acetyltransferase
JOHLMJPM_00955 6.7e-116 yfbR S HD containing hydrolase-like enzyme
JOHLMJPM_00957 4.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
JOHLMJPM_00958 5.6e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
JOHLMJPM_00959 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
JOHLMJPM_00960 1.1e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JOHLMJPM_00961 9.5e-172 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
JOHLMJPM_00962 5.5e-30 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
JOHLMJPM_00963 1.7e-54 pspC KT PspC domain protein
JOHLMJPM_00964 1.4e-119 phoU P Plays a role in the regulation of phosphate uptake
JOHLMJPM_00965 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOHLMJPM_00966 1.8e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOHLMJPM_00967 5.9e-155 pstA P Phosphate transport system permease protein PstA
JOHLMJPM_00968 2e-158 pstC P probably responsible for the translocation of the substrate across the membrane
JOHLMJPM_00969 2.5e-161 pstS P Phosphate
JOHLMJPM_00970 1.1e-248 phoR 2.7.13.3 T Histidine kinase
JOHLMJPM_00971 2e-129 K response regulator
JOHLMJPM_00972 1e-223 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
JOHLMJPM_00973 8.6e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JOHLMJPM_00974 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
JOHLMJPM_00975 7.9e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JOHLMJPM_00976 1.1e-124 comFC S Competence protein
JOHLMJPM_00977 1.5e-255 comFA L Helicase C-terminal domain protein
JOHLMJPM_00978 1.1e-116 yvyE 3.4.13.9 S YigZ family
JOHLMJPM_00979 3.6e-178 tagO 2.7.8.33, 2.7.8.35 M transferase
JOHLMJPM_00980 1.6e-60 lrgA S LrgA family
JOHLMJPM_00981 3.7e-140 lrgB M LrgB-like family
JOHLMJPM_00982 0.0 ydaO E amino acid
JOHLMJPM_00983 6.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
JOHLMJPM_00984 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JOHLMJPM_00985 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JOHLMJPM_00986 0.0 uup S ABC transporter, ATP-binding protein
JOHLMJPM_00987 7.5e-46 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
JOHLMJPM_00988 2.3e-215 yeaN P Transporter, major facilitator family protein
JOHLMJPM_00989 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JOHLMJPM_00990 1.8e-110 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
JOHLMJPM_00991 3.2e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
JOHLMJPM_00992 4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
JOHLMJPM_00993 9e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JOHLMJPM_00994 1.7e-38 yabA L Involved in initiation control of chromosome replication
JOHLMJPM_00995 3.2e-181 holB 2.7.7.7 L DNA polymerase III
JOHLMJPM_00996 2.2e-54 yaaQ S Cyclic-di-AMP receptor
JOHLMJPM_00997 1.2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JOHLMJPM_00998 1.3e-38 yaaL S Protein of unknown function (DUF2508)
JOHLMJPM_00999 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JOHLMJPM_01000 1.5e-39 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JOHLMJPM_01001 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOHLMJPM_01002 9.8e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
JOHLMJPM_01003 1.9e-112 rsmC 2.1.1.172 J Methyltransferase
JOHLMJPM_01004 4.9e-37 nrdH O Glutaredoxin
JOHLMJPM_01005 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOHLMJPM_01006 8.5e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JOHLMJPM_01007 4.6e-171 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
JOHLMJPM_01008 4.9e-110 yvdD 3.2.2.10 S Belongs to the LOG family
JOHLMJPM_01009 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOHLMJPM_01010 4e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
JOHLMJPM_01011 6.9e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JOHLMJPM_01012 1.2e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
JOHLMJPM_01013 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JOHLMJPM_01014 1.1e-98 nusG K Participates in transcription elongation, termination and antitermination
JOHLMJPM_01015 3.3e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
JOHLMJPM_01016 1.5e-98 sigH K Sigma-70 region 2
JOHLMJPM_01017 1.8e-90 yacP S YacP-like NYN domain
JOHLMJPM_01018 2.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOHLMJPM_01019 7.8e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
JOHLMJPM_01020 7.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOHLMJPM_01021 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JOHLMJPM_01022 3.7e-213 yacL S domain protein
JOHLMJPM_01023 1.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JOHLMJPM_01024 8.7e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
JOHLMJPM_01025 4.1e-56
JOHLMJPM_01026 5.3e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JOHLMJPM_01028 5e-259 pepC 3.4.22.40 E Peptidase C1-like family
JOHLMJPM_01029 4.5e-230 V Beta-lactamase
JOHLMJPM_01030 1.5e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JOHLMJPM_01031 1.3e-174 EG EamA-like transporter family
JOHLMJPM_01032 6.1e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
JOHLMJPM_01033 1.6e-205 brpA K Cell envelope-like function transcriptional attenuator common domain protein
JOHLMJPM_01034 1.9e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
JOHLMJPM_01035 3.9e-213 XK27_06930 V domain protein
JOHLMJPM_01036 2.8e-102 K Bacterial regulatory proteins, tetR family
JOHLMJPM_01037 1.9e-118 yliE T EAL domain
JOHLMJPM_01038 7.3e-21 2.7.7.65 T diguanylate cyclase
JOHLMJPM_01039 9.1e-175 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHLMJPM_01040 1.8e-189 L Helix-turn-helix domain
JOHLMJPM_01041 1e-37 S Cytochrome B5
JOHLMJPM_01042 2.1e-31 cspC K Cold shock protein
JOHLMJPM_01043 1.6e-111 XK27_00220 S Dienelactone hydrolase family
JOHLMJPM_01044 4.4e-52
JOHLMJPM_01045 6.7e-220 mutY L A G-specific adenine glycosylase
JOHLMJPM_01046 4.7e-307 E Bacterial extracellular solute-binding proteins, family 5 Middle
JOHLMJPM_01047 0.0 pelX M domain, Protein
JOHLMJPM_01048 1.1e-52
JOHLMJPM_01049 4.7e-196 6.3.1.20 H Lipoate-protein ligase
JOHLMJPM_01050 9.7e-67 gcvH E glycine cleavage
JOHLMJPM_01051 5.1e-184 tas C Aldo/keto reductase family
JOHLMJPM_01052 2.1e-32
JOHLMJPM_01053 1.6e-177 EG EamA-like transporter family
JOHLMJPM_01054 8.6e-114 metI P ABC transporter permease
JOHLMJPM_01055 2e-194 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JOHLMJPM_01056 3.5e-146 P Belongs to the nlpA lipoprotein family
JOHLMJPM_01057 4.4e-100 tag 3.2.2.20 L glycosylase
JOHLMJPM_01058 0.0 E ABC transporter, substratebinding protein
JOHLMJPM_01060 0.0 3.2.1.21 GH3 G hydrolase, family 3
JOHLMJPM_01061 1.3e-192 pva1 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
JOHLMJPM_01062 0.0 sbcC L Putative exonuclease SbcCD, C subunit
JOHLMJPM_01063 1e-212 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
JOHLMJPM_01064 5.8e-108 tag 3.2.2.20 L glycosylase
JOHLMJPM_01065 2e-153 S Zinc-dependent metalloprotease
JOHLMJPM_01066 7.7e-169 XK27_00880 3.5.1.28 M hydrolase, family 25
JOHLMJPM_01067 3.8e-207 G Glycosyl hydrolases family 8
JOHLMJPM_01068 8.6e-56 yphJ 4.1.1.44 S decarboxylase
JOHLMJPM_01069 5.1e-80 yphH S Cupin domain
JOHLMJPM_01070 2e-76 K helix_turn_helix, mercury resistance
JOHLMJPM_01071 2e-100 yobS K Bacterial regulatory proteins, tetR family
JOHLMJPM_01072 1.2e-09 K MarR family
JOHLMJPM_01073 1.9e-231
JOHLMJPM_01074 3.4e-160 dkgB S reductase
JOHLMJPM_01075 7e-204 EGP Major facilitator Superfamily
JOHLMJPM_01076 3.2e-196 EGP Major facilitator Superfamily
JOHLMJPM_01077 2.1e-137 C Oxidoreductase
JOHLMJPM_01078 3.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
JOHLMJPM_01079 2e-19 K helix_turn_helix, arabinose operon control protein
JOHLMJPM_01080 6.7e-27 K helix_turn_helix, arabinose operon control protein
JOHLMJPM_01081 5.2e-61 S Domain of unknown function (DUF4430)
JOHLMJPM_01082 5.9e-178 U FFAT motif binding
JOHLMJPM_01083 3.6e-114 S ECF-type riboflavin transporter, S component
JOHLMJPM_01084 1.5e-308 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
JOHLMJPM_01085 1.1e-161 P ABC-type cobalt transport system permease component CbiQ and related transporters
JOHLMJPM_01086 4.9e-72
JOHLMJPM_01087 1.5e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
JOHLMJPM_01088 1.2e-285 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
JOHLMJPM_01089 3.5e-160 K LysR substrate binding domain
JOHLMJPM_01090 2.4e-71 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
JOHLMJPM_01091 0.0 epsA I PAP2 superfamily
JOHLMJPM_01092 7.6e-58 S Domain of unknown function (DU1801)
JOHLMJPM_01093 3.2e-110 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
JOHLMJPM_01094 6.8e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JOHLMJPM_01095 0.0 lmrA 3.6.3.44 V ABC transporter
JOHLMJPM_01096 2e-97 rmaB K Transcriptional regulator, MarR family
JOHLMJPM_01097 5.7e-124 S membrane transporter protein
JOHLMJPM_01098 1.5e-141 3.1.3.48 T Tyrosine phosphatase family
JOHLMJPM_01099 1.4e-125
JOHLMJPM_01100 1e-125 skfE V ATPases associated with a variety of cellular activities
JOHLMJPM_01101 1.9e-62 yvoA_1 K Transcriptional regulator, GntR family
JOHLMJPM_01102 6.4e-179 3.5.2.6 V Beta-lactamase enzyme family
JOHLMJPM_01103 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
JOHLMJPM_01104 3.3e-130 S haloacid dehalogenase-like hydrolase
JOHLMJPM_01105 7.4e-206 bcr1 EGP Major facilitator Superfamily
JOHLMJPM_01106 5.9e-146 S Sucrose-6F-phosphate phosphohydrolase
JOHLMJPM_01107 1.6e-156 map 3.4.11.18 E Methionine Aminopeptidase
JOHLMJPM_01108 1e-101
JOHLMJPM_01110 7.5e-132 ydfG S KR domain
JOHLMJPM_01111 8e-66 hxlR K HxlR-like helix-turn-helix
JOHLMJPM_01112 7.4e-60 asp2 S Asp23 family, cell envelope-related function
JOHLMJPM_01113 4.3e-71 asp S Asp23 family, cell envelope-related function
JOHLMJPM_01114 3.4e-25
JOHLMJPM_01115 5.7e-92
JOHLMJPM_01116 8.8e-19 S Transglycosylase associated protein
JOHLMJPM_01117 3.1e-159
JOHLMJPM_01118 1.4e-271 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
JOHLMJPM_01119 5.1e-138 chaT1 U Major Facilitator Superfamily
JOHLMJPM_01120 2.8e-37 chaT1 EGP Major facilitator Superfamily
JOHLMJPM_01121 2e-95 laaE K Transcriptional regulator PadR-like family
JOHLMJPM_01122 1.5e-65 lysM M LysM domain
JOHLMJPM_01123 3.8e-128 XK27_07210 6.1.1.6 S B3 4 domain
JOHLMJPM_01124 3.1e-119 iprA K Cyclic nucleotide-monophosphate binding domain
JOHLMJPM_01125 3.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
JOHLMJPM_01126 6.8e-217 arcT 2.6.1.1 E Aminotransferase
JOHLMJPM_01127 3.8e-257 arcD E Arginine ornithine antiporter
JOHLMJPM_01128 3.3e-197 argF 2.1.3.3, 2.1.3.6, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOHLMJPM_01129 2.3e-237 arcA 3.5.3.6 E Arginine
JOHLMJPM_01130 9.4e-281 S C4-dicarboxylate anaerobic carrier
JOHLMJPM_01131 1.2e-225 2.1.1.80, 2.7.13.3, 3.1.1.61 T histidine kinase DNA gyrase B
JOHLMJPM_01132 2.7e-149 KT YcbB domain
JOHLMJPM_01133 1.2e-280 arcD S C4-dicarboxylate anaerobic carrier
JOHLMJPM_01134 7e-261 ytjP 3.5.1.18 E Dipeptidase
JOHLMJPM_01136 2.9e-210 ykiI
JOHLMJPM_01137 2.5e-109 thiJ-2 3.5.1.124 S DJ-1/PfpI family
JOHLMJPM_01138 9.8e-164 3.1.3.48 T Tyrosine phosphatase family
JOHLMJPM_01139 1.4e-175 L Integrase core domain
JOHLMJPM_01140 1.5e-112 tra L Transposase and inactivated derivatives, IS30 family
JOHLMJPM_01142 1.3e-100 S Polysaccharide biosynthesis protein
JOHLMJPM_01143 1.2e-72 C Polysaccharide pyruvyl transferase
JOHLMJPM_01144 3.3e-32 M Glycosyltransferase group 2 family protein
JOHLMJPM_01145 6.1e-33 cpsJ S Glycosyltransferase like family 2
JOHLMJPM_01146 2e-115 M Glycosyl transferases group 1
JOHLMJPM_01147 5.8e-96 lsgF M Glycosyltransferase, group 2 family protein
JOHLMJPM_01148 6.9e-67 tuaA M Bacterial sugar transferase
JOHLMJPM_01149 4.7e-42 cps2D 5.1.3.2 M RmlD substrate binding domain
JOHLMJPM_01150 8.6e-17 cps2D 5.1.3.2 M RmlD substrate binding domain
JOHLMJPM_01151 7.8e-119 L Transposase and inactivated derivatives, IS30 family
JOHLMJPM_01152 1.3e-36 L Transposase and inactivated derivatives
JOHLMJPM_01153 1.4e-38 L transposase activity
JOHLMJPM_01154 2e-101 L HTH-like domain
JOHLMJPM_01155 5.6e-155 L COG2801 Transposase and inactivated derivatives
JOHLMJPM_01156 1e-63 tuaA M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
JOHLMJPM_01157 9.1e-106 cps2D 5.1.3.2 M RmlD substrate binding domain
JOHLMJPM_01158 6.4e-121 ywqE 3.1.3.48 GM PHP domain protein
JOHLMJPM_01159 3.5e-127 ywqD 2.7.10.1 D Capsular exopolysaccharide family
JOHLMJPM_01160 1e-89 epsB M biosynthesis protein
JOHLMJPM_01161 1.2e-108 L Transposase and inactivated derivatives, IS30 family
JOHLMJPM_01162 0.0 L Transposase
JOHLMJPM_01163 3.5e-223 EGP Major facilitator Superfamily
JOHLMJPM_01164 6e-39 S Protein of unknown function (DUF3781)
JOHLMJPM_01165 7.5e-39
JOHLMJPM_01166 5.3e-89 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
JOHLMJPM_01167 1.2e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JOHLMJPM_01168 4.3e-283 M domain protein
JOHLMJPM_01169 2.7e-170 K AI-2E family transporter
JOHLMJPM_01170 3e-215 xylR GK ROK family
JOHLMJPM_01171 1e-125
JOHLMJPM_01172 9.8e-238 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JOHLMJPM_01173 4.3e-53 azlD S branched-chain amino acid
JOHLMJPM_01174 8.5e-137 azlC E AzlC protein
JOHLMJPM_01175 1.4e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
JOHLMJPM_01176 2.9e-254 gor 1.8.1.7 C Glutathione reductase
JOHLMJPM_01177 1e-36
JOHLMJPM_01178 5.4e-163 V domain protein
JOHLMJPM_01179 4.4e-239 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JOHLMJPM_01180 5.1e-215 hpk31 2.7.13.3 T Histidine kinase
JOHLMJPM_01181 3.5e-123 K response regulator
JOHLMJPM_01182 2.8e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
JOHLMJPM_01183 1e-107
JOHLMJPM_01184 3.1e-133 XK27_01040 S Protein of unknown function (DUF1129)
JOHLMJPM_01185 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
JOHLMJPM_01186 8.5e-33 yyzM S Bacterial protein of unknown function (DUF951)
JOHLMJPM_01187 3.4e-155 spo0J K Belongs to the ParB family
JOHLMJPM_01188 4.1e-136 soj D Sporulation initiation inhibitor
JOHLMJPM_01189 5e-148 noc K Belongs to the ParB family
JOHLMJPM_01190 1.7e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
JOHLMJPM_01191 1.6e-165 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
JOHLMJPM_01192 2.8e-168 rihC 3.2.2.1, 3.2.2.8 F Nucleoside
JOHLMJPM_01193 9.8e-215 pbuO_1 S Permease family
JOHLMJPM_01194 5.3e-226 nupG F Nucleoside
JOHLMJPM_01195 3.6e-154 5.4.2.7 G Metalloenzyme superfamily
JOHLMJPM_01196 1.5e-112 GM NmrA-like family
JOHLMJPM_01197 8.2e-44
JOHLMJPM_01198 2.8e-89
JOHLMJPM_01199 4.1e-40
JOHLMJPM_01200 1.1e-62 K HxlR-like helix-turn-helix
JOHLMJPM_01201 3.5e-34
JOHLMJPM_01202 1e-116
JOHLMJPM_01203 4.3e-195
JOHLMJPM_01204 4.7e-102
JOHLMJPM_01205 4e-94
JOHLMJPM_01206 6.6e-68
JOHLMJPM_01207 5.3e-223 EK Aminotransferase, class I
JOHLMJPM_01208 4.9e-165 K LysR substrate binding domain
JOHLMJPM_01209 6.2e-11 S Protein of unknown function (DUF2922)
JOHLMJPM_01210 5.1e-27
JOHLMJPM_01211 6.4e-99 K DNA-templated transcription, initiation
JOHLMJPM_01212 7.3e-203
JOHLMJPM_01213 5.5e-65
JOHLMJPM_01214 1.2e-54
JOHLMJPM_01215 1.5e-194 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
JOHLMJPM_01216 1e-229 macB3 V ABC transporter, ATP-binding protein
JOHLMJPM_01217 6.8e-20 macB3 V ABC transporter, ATP-binding protein
JOHLMJPM_01218 2.1e-109 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
JOHLMJPM_01219 4.9e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOHLMJPM_01220 3.4e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JOHLMJPM_01221 2.7e-149 vdlC S Enoyl-(Acyl carrier protein) reductase
JOHLMJPM_01222 2.8e-129 ybbM S Uncharacterised protein family (UPF0014)
JOHLMJPM_01223 4.2e-118 ybbL S ABC transporter, ATP-binding protein
JOHLMJPM_01224 2.5e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JOHLMJPM_01225 3.7e-74
JOHLMJPM_01226 3.5e-88 rmeB K transcriptional regulator, MerR family
JOHLMJPM_01227 4.6e-96 J glyoxalase III activity
JOHLMJPM_01228 1.2e-133 XK27_00890 S Domain of unknown function (DUF368)
JOHLMJPM_01229 2.8e-134 K helix_turn_helix, mercury resistance
JOHLMJPM_01230 1.8e-223 xylR GK ROK family
JOHLMJPM_01231 2.9e-159 akr5f 1.1.1.346 C Aldo keto reductase
JOHLMJPM_01232 5.2e-248 rarA L recombination factor protein RarA
JOHLMJPM_01233 1.8e-279 rny S Endoribonuclease that initiates mRNA decay
JOHLMJPM_01234 5.4e-127 yoaK S Protein of unknown function (DUF1275)
JOHLMJPM_01235 2e-177 D Alpha beta
JOHLMJPM_01236 0.0 pepF2 E Oligopeptidase F
JOHLMJPM_01237 5.4e-74 K Transcriptional regulator
JOHLMJPM_01238 8.7e-164
JOHLMJPM_01239 3.3e-192 S DUF218 domain
JOHLMJPM_01240 1.5e-253 brnQ U Component of the transport system for branched-chain amino acids
JOHLMJPM_01241 1.6e-160 nanK 2.7.1.2 GK ROK family
JOHLMJPM_01242 1.8e-256 frlA E Amino acid permease
JOHLMJPM_01243 1.5e-253 brnQ U Component of the transport system for branched-chain amino acids
JOHLMJPM_01244 1e-21 S SEC-C Motif Domain Protein
JOHLMJPM_01245 2.2e-20 yecA S SEC-C Motif Domain Protein
JOHLMJPM_01246 2.6e-196 S DNA/RNA non-specific endonuclease
JOHLMJPM_01248 2e-52
JOHLMJPM_01249 3e-78 K Winged helix DNA-binding domain
JOHLMJPM_01250 1.3e-111 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
JOHLMJPM_01251 7.9e-105 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
JOHLMJPM_01252 7.9e-114
JOHLMJPM_01253 4.2e-191 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
JOHLMJPM_01254 3.8e-84 iap CBM50 M NlpC P60 family
JOHLMJPM_01255 1.7e-240 L Transposase
JOHLMJPM_01256 2.9e-293 ytgP S Polysaccharide biosynthesis protein
JOHLMJPM_01257 3.8e-60 K Helix-turn-helix domain
JOHLMJPM_01258 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
JOHLMJPM_01259 3.1e-170 panE2 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JOHLMJPM_01260 8.8e-44
JOHLMJPM_01261 1.9e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JOHLMJPM_01262 0.0 yjcE P Sodium proton antiporter
JOHLMJPM_01263 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
JOHLMJPM_01264 1.2e-308 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
JOHLMJPM_01265 5.2e-119 yoaK S Protein of unknown function (DUF1275)
JOHLMJPM_01266 6.6e-157 rihA F Inosine-uridine preferring nucleoside hydrolase
JOHLMJPM_01268 1.9e-178 K helix_turn _helix lactose operon repressor
JOHLMJPM_01269 6.1e-29 mcbG S Pentapeptide repeats (8 copies)
JOHLMJPM_01270 1e-99 ywlG S Belongs to the UPF0340 family
JOHLMJPM_01271 4e-84 hmpT S ECF-type riboflavin transporter, S component
JOHLMJPM_01272 7.4e-141 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H Phosphomethylpyrimidine kinase
JOHLMJPM_01273 1.1e-261 norG_2 K Aminotransferase class I and II
JOHLMJPM_01274 3.9e-223 lytR5 K Cell envelope-related transcriptional attenuator domain
JOHLMJPM_01275 1e-139 P ATPases associated with a variety of cellular activities
JOHLMJPM_01276 1.9e-144 opuAB P Binding-protein-dependent transport system inner membrane component
JOHLMJPM_01277 1e-159 opuAB P Binding-protein-dependent transport system inner membrane component
JOHLMJPM_01278 2.5e-228 rodA D Cell cycle protein
JOHLMJPM_01279 4.3e-95
JOHLMJPM_01281 8e-72 4.4.1.5 E Glyoxalase
JOHLMJPM_01282 1.9e-141 S Membrane
JOHLMJPM_01283 2.8e-185 tdh 1.1.1.14 C Zinc-binding dehydrogenase
JOHLMJPM_01284 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
JOHLMJPM_01285 4.4e-76
JOHLMJPM_01286 4.1e-206 gldA 1.1.1.6 C dehydrogenase
JOHLMJPM_01287 5.7e-55 ykkC P Small Multidrug Resistance protein
JOHLMJPM_01288 9.7e-52 sugE P Multidrug resistance protein
JOHLMJPM_01289 4.2e-108 speG J Acetyltransferase (GNAT) domain
JOHLMJPM_01290 3.6e-146 G Belongs to the phosphoglycerate mutase family
JOHLMJPM_01292 5.8e-279 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
JOHLMJPM_01293 1.7e-63 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
JOHLMJPM_01294 1.6e-199 nlhH_1 I alpha/beta hydrolase fold
JOHLMJPM_01295 9.5e-253 xylP2 G symporter
JOHLMJPM_01296 9.1e-175 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHLMJPM_01297 1.8e-189 L Helix-turn-helix domain
JOHLMJPM_01298 1.3e-257 ydiC1 EGP Major facilitator Superfamily
JOHLMJPM_01299 1.6e-91 K Transcriptional regulator PadR-like family
JOHLMJPM_01300 2.7e-82 merR K MerR family regulatory protein
JOHLMJPM_01301 4.8e-63 iap CBM50 M NlpC P60 family
JOHLMJPM_01302 8.3e-78 yjcF K protein acetylation
JOHLMJPM_01303 9e-124 pgm3 G phosphoglycerate mutase family
JOHLMJPM_01304 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JOHLMJPM_01305 2.9e-182 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
JOHLMJPM_01306 2.1e-145 S Alpha/beta hydrolase of unknown function (DUF915)
JOHLMJPM_01307 2.7e-191 S Protease prsW family
JOHLMJPM_01308 3.1e-178 iunH2 3.2.2.1, 3.2.2.8 F nucleoside hydrolase
JOHLMJPM_01309 1.6e-07 yvlA
JOHLMJPM_01310 2.7e-88
JOHLMJPM_01311 2.4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
JOHLMJPM_01312 4.2e-155 S Alpha/beta hydrolase of unknown function (DUF915)
JOHLMJPM_01313 6.8e-237 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
JOHLMJPM_01314 2.2e-142 S Uncharacterized protein conserved in bacteria (DUF2087)
JOHLMJPM_01315 4.1e-61 S LuxR family transcriptional regulator
JOHLMJPM_01316 7.4e-134 cat 2.3.1.28 V Chloramphenicol acetyltransferase
JOHLMJPM_01317 2.6e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JOHLMJPM_01318 1.9e-169 dacA 3.4.16.4 M Belongs to the peptidase S11 family
JOHLMJPM_01319 4.4e-95 S ABC transporter permease
JOHLMJPM_01320 7.7e-258 P ABC transporter
JOHLMJPM_01321 7.5e-115 P Cobalt transport protein
JOHLMJPM_01322 1.2e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JOHLMJPM_01323 6.6e-60
JOHLMJPM_01324 1.1e-08
JOHLMJPM_01326 5.5e-32
JOHLMJPM_01327 7.1e-217
JOHLMJPM_01328 6e-188 ansA 3.5.1.1 EJ Asparaginase
JOHLMJPM_01329 2.9e-25
JOHLMJPM_01330 2.7e-247 pbuX F xanthine permease
JOHLMJPM_01331 7.2e-169 natA S ABC transporter, ATP-binding protein
JOHLMJPM_01332 3.5e-214 natB CP ABC-2 family transporter protein
JOHLMJPM_01334 9.3e-253 yjjP S Putative threonine/serine exporter
JOHLMJPM_01335 2e-160 degV S Uncharacterised protein, DegV family COG1307
JOHLMJPM_01336 7.7e-154 1.1.1.2, 1.1.1.307 C Aldo keto reductase
JOHLMJPM_01337 1.5e-64 S Protein of unknown function (DUF1722)
JOHLMJPM_01338 2.6e-69 yqeB S Pyrimidine dimer DNA glycosylase
JOHLMJPM_01339 3.1e-283 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
JOHLMJPM_01340 5.8e-126 K Crp-like helix-turn-helix domain
JOHLMJPM_01341 1.1e-239 larA 5.1.2.1 S Domain of unknown function (DUF2088)
JOHLMJPM_01342 1.2e-132 cpmA S AIR carboxylase
JOHLMJPM_01343 1.6e-230 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
JOHLMJPM_01344 2.4e-150 larE S NAD synthase
JOHLMJPM_01345 7.7e-123 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JOHLMJPM_01346 4.5e-180 hoxN U High-affinity nickel-transport protein
JOHLMJPM_01347 3.2e-42 aroD S Serine hydrolase (FSH1)
JOHLMJPM_01348 1.4e-32 aroD S Serine hydrolase (FSH1)
JOHLMJPM_01349 5.4e-42 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
JOHLMJPM_01351 3.1e-209 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
JOHLMJPM_01352 5.9e-149 potB P ABC transporter permease
JOHLMJPM_01353 6.8e-134 potC P ABC transporter permease
JOHLMJPM_01354 6.8e-206 potD P ABC transporter
JOHLMJPM_01355 4.8e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
JOHLMJPM_01356 4.7e-144 pstA P Phosphate transport system permease protein PstA
JOHLMJPM_01357 1e-168 pstC P probably responsible for the translocation of the substrate across the membrane
JOHLMJPM_01358 2.4e-156 pstS P Phosphate
JOHLMJPM_01359 4.5e-58
JOHLMJPM_01360 2.1e-31
JOHLMJPM_01361 1.8e-43
JOHLMJPM_01362 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
JOHLMJPM_01363 1.7e-125
JOHLMJPM_01364 7.9e-179 sepS16B
JOHLMJPM_01365 9.8e-286 V ABC transporter transmembrane region
JOHLMJPM_01366 0.0 KLT Protein kinase domain
JOHLMJPM_01368 1e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
JOHLMJPM_01369 4.8e-81 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JOHLMJPM_01370 1e-298 E amino acid
JOHLMJPM_01371 5.4e-119 S membrane
JOHLMJPM_01372 4.6e-115 S VIT family
JOHLMJPM_01373 5.7e-91 perR P Belongs to the Fur family
JOHLMJPM_01374 4.1e-179 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
JOHLMJPM_01376 1e-126 yibF S overlaps another CDS with the same product name
JOHLMJPM_01377 2.8e-202 yibE S overlaps another CDS with the same product name
JOHLMJPM_01379 9.6e-83 uspA T Belongs to the universal stress protein A family
JOHLMJPM_01380 7e-132
JOHLMJPM_01381 1.5e-86 K helix_turn_helix multiple antibiotic resistance protein
JOHLMJPM_01382 0.0 pepO 3.4.24.71 O Peptidase family M13
JOHLMJPM_01384 7.5e-54
JOHLMJPM_01385 7.7e-97
JOHLMJPM_01386 0.0 M domain protein
JOHLMJPM_01387 1.4e-175 L Integrase core domain
JOHLMJPM_01388 9.1e-175 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHLMJPM_01391 9e-147 K response regulator
JOHLMJPM_01392 3.5e-269 T PhoQ Sensor
JOHLMJPM_01393 1.5e-211 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
JOHLMJPM_01394 1.3e-154 glcU U sugar transport
JOHLMJPM_01395 7.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
JOHLMJPM_01396 0.0 S Bacterial membrane protein YfhO
JOHLMJPM_01397 5.2e-81 tspO T TspO/MBR family
JOHLMJPM_01398 3.8e-99 S Protein of unknown function (DUF1211)
JOHLMJPM_01401 5.8e-164 S NAD:arginine ADP-ribosyltransferase
JOHLMJPM_01402 9.8e-200 ybiR P Citrate transporter
JOHLMJPM_01403 4.9e-122 yliE T Putative diguanylate phosphodiesterase
JOHLMJPM_01404 1.8e-53 2.7.7.65 T diguanylate cyclase activity
JOHLMJPM_01405 4.5e-169 arcC 2.7.2.2 E Belongs to the carbamate kinase family
JOHLMJPM_01406 1e-217 aguA 3.5.3.12 E agmatine deiminase
JOHLMJPM_01407 2e-234 aguD E Amino Acid
JOHLMJPM_01408 6.6e-198 ptcA 2.1.3.3, 2.1.3.6 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JOHLMJPM_01409 8.1e-239 nhaC C Na H antiporter NhaC
JOHLMJPM_01410 6.8e-262 E Amino acid permease
JOHLMJPM_01411 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
JOHLMJPM_01412 2.2e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JOHLMJPM_01413 1.3e-38
JOHLMJPM_01416 2.7e-208 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
JOHLMJPM_01417 1.9e-26
JOHLMJPM_01418 6.3e-157 EG EamA-like transporter family
JOHLMJPM_01419 1.5e-304 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
JOHLMJPM_01420 3.6e-39
JOHLMJPM_01421 6.4e-14 S Transglycosylase associated protein
JOHLMJPM_01422 7.8e-14 yjdF S Protein of unknown function (DUF2992)
JOHLMJPM_01423 1.2e-157 K Transcriptional regulator
JOHLMJPM_01424 8.8e-308 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
JOHLMJPM_01425 3.2e-138 S Belongs to the UPF0246 family
JOHLMJPM_01426 7.6e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JOHLMJPM_01427 5.3e-122 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
JOHLMJPM_01428 7.5e-217 naiP EGP Major facilitator Superfamily
JOHLMJPM_01429 6.5e-136 S Protein of unknown function
JOHLMJPM_01430 7.3e-177 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
JOHLMJPM_01431 2.1e-165 G Belongs to the carbohydrate kinase PfkB family
JOHLMJPM_01432 1.3e-257 F Belongs to the purine-cytosine permease (2.A.39) family
JOHLMJPM_01433 2.6e-191 yegU O ADP-ribosylglycohydrolase
JOHLMJPM_01434 2.3e-122 yihL K UTRA
JOHLMJPM_01435 1.5e-166 yhaZ L DNA alkylation repair enzyme
JOHLMJPM_01436 4.5e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
JOHLMJPM_01437 0.0 tetP J elongation factor G
JOHLMJPM_01438 8.7e-234 EK Aminotransferase, class I
JOHLMJPM_01439 9.7e-138 IQ reductase
JOHLMJPM_01440 6.8e-98 K Bacterial regulatory proteins, tetR family
JOHLMJPM_01441 1.6e-73 S COG NOG18757 non supervised orthologous group
JOHLMJPM_01442 4.2e-209 pmrB EGP Major facilitator Superfamily
JOHLMJPM_01443 1.9e-115 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
JOHLMJPM_01444 7.2e-81
JOHLMJPM_01445 1.5e-25
JOHLMJPM_01446 4.9e-119 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
JOHLMJPM_01447 2.7e-224 LO Uncharacterized conserved protein (DUF2075)
JOHLMJPM_01448 4.1e-27 K Transcriptional
JOHLMJPM_01449 9.5e-74
JOHLMJPM_01450 0.0 M Mycoplasma protein of unknown function, DUF285
JOHLMJPM_01451 4.9e-113 S NADPH-dependent FMN reductase
JOHLMJPM_01452 1.7e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JOHLMJPM_01453 2.9e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JOHLMJPM_01454 2e-35 yaaA S S4 domain protein YaaA
JOHLMJPM_01455 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JOHLMJPM_01456 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOHLMJPM_01457 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOHLMJPM_01458 1.9e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
JOHLMJPM_01459 3e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JOHLMJPM_01460 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JOHLMJPM_01461 4.7e-232 Q Imidazolonepropionase and related amidohydrolases
JOHLMJPM_01462 4e-303 E ABC transporter, substratebinding protein
JOHLMJPM_01463 2.4e-144
JOHLMJPM_01464 9.7e-230 Q Imidazolonepropionase and related amidohydrolases
JOHLMJPM_01465 2.8e-304 E ABC transporter, substratebinding protein
JOHLMJPM_01466 1e-99 K Bacterial regulatory proteins, tetR family
JOHLMJPM_01467 1e-38 S response to heat
JOHLMJPM_01468 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JOHLMJPM_01469 7.2e-64 rplI J Binds to the 23S rRNA
JOHLMJPM_01471 6e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JOHLMJPM_01472 3.8e-101 S NADPH-dependent FMN reductase
JOHLMJPM_01473 1.1e-212 yttB EGP Major facilitator Superfamily
JOHLMJPM_01474 1.1e-22
JOHLMJPM_01475 2.8e-304 E ABC transporter, substratebinding protein
JOHLMJPM_01476 1.3e-38
JOHLMJPM_01477 1.1e-130 E Matrixin
JOHLMJPM_01479 5.7e-132 K response regulator
JOHLMJPM_01480 0.0 vicK 2.7.13.3 T Histidine kinase
JOHLMJPM_01481 1.1e-239 yycH S YycH protein
JOHLMJPM_01482 2.6e-152 yycI S YycH protein
JOHLMJPM_01483 3.4e-157 vicX 3.1.26.11 S domain protein
JOHLMJPM_01484 4e-195 htrA 3.4.21.107 O serine protease
JOHLMJPM_01485 7.3e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JOHLMJPM_01486 8.2e-23 S Protein of unknown function (DUF2971)
JOHLMJPM_01488 1.2e-82
JOHLMJPM_01489 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
JOHLMJPM_01490 6.5e-79 K Acetyltransferase (GNAT) domain
JOHLMJPM_01491 1.6e-42 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JOHLMJPM_01492 1.6e-42 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
JOHLMJPM_01493 5.4e-71 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHLMJPM_01494 9.1e-175 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHLMJPM_01495 5.3e-62
JOHLMJPM_01496 1.5e-121
JOHLMJPM_01497 9.8e-214 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JOHLMJPM_01498 3.9e-260 bmr3 EGP Major facilitator Superfamily
JOHLMJPM_01499 1.8e-56 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
JOHLMJPM_01500 4.5e-120 dck 2.7.1.74 F Deoxynucleoside kinase
JOHLMJPM_01501 1.2e-143 S haloacid dehalogenase-like hydrolase
JOHLMJPM_01502 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
JOHLMJPM_01503 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
JOHLMJPM_01504 5.9e-177 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOHLMJPM_01505 1.1e-37
JOHLMJPM_01506 2.3e-122 S CAAX protease self-immunity
JOHLMJPM_01507 9.4e-83 ohrR K Transcriptional regulator
JOHLMJPM_01508 1.2e-83 V VanZ like family
JOHLMJPM_01509 5.1e-47
JOHLMJPM_01511 1.9e-126 L Helix-turn-helix domain
JOHLMJPM_01512 0.0 uvrA3 L ABC transporter
JOHLMJPM_01515 0.0
JOHLMJPM_01516 1.3e-37
JOHLMJPM_01517 3.1e-275 pipD E Peptidase family C69
JOHLMJPM_01518 4.9e-120 ntcA2 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
JOHLMJPM_01519 0.0 asnB 6.3.5.4 E Asparagine synthase
JOHLMJPM_01520 2.3e-253 yxbA 6.3.1.12 S ATP-grasp enzyme
JOHLMJPM_01521 1.6e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JOHLMJPM_01522 8.6e-54 S Protein of unknown function (DUF1516)
JOHLMJPM_01523 4e-98 1.5.1.3 H RibD C-terminal domain
JOHLMJPM_01524 1.1e-231 3.2.1.96, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JOHLMJPM_01525 1.1e-17
JOHLMJPM_01527 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
JOHLMJPM_01528 4.7e-79 argR K Regulates arginine biosynthesis genes
JOHLMJPM_01529 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
JOHLMJPM_01530 1.3e-52 yheA S Belongs to the UPF0342 family
JOHLMJPM_01531 1.9e-233 yhaO L Ser Thr phosphatase family protein
JOHLMJPM_01532 0.0 L AAA domain
JOHLMJPM_01533 7.1e-186 S Metal dependent phosphohydrolases with conserved 'HD' motif.
JOHLMJPM_01534 9.1e-151 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
JOHLMJPM_01535 1.9e-50
JOHLMJPM_01536 3.1e-83 hit FG histidine triad
JOHLMJPM_01537 3e-135 ecsA V ABC transporter, ATP-binding protein
JOHLMJPM_01538 5.9e-222 ecsB U ABC transporter
JOHLMJPM_01539 1.9e-149 ytmP 2.7.1.89 M Choline/ethanolamine kinase
JOHLMJPM_01540 1.6e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
JOHLMJPM_01541 1.5e-208 coiA 3.6.4.12 S Competence protein
JOHLMJPM_01542 0.0 pepF E oligoendopeptidase F
JOHLMJPM_01543 2.5e-158 degV S DegV family
JOHLMJPM_01544 1.4e-113 yjbH Q Thioredoxin
JOHLMJPM_01545 3.3e-118 yjbM 2.7.6.5 S RelA SpoT domain protein
JOHLMJPM_01546 1.4e-150 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JOHLMJPM_01547 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
JOHLMJPM_01548 1.1e-68 3.1.3.18 S Pfam Methyltransferase
JOHLMJPM_01549 8.4e-60 alr 5.1.1.1, 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JOHLMJPM_01550 1.3e-63 S Pfam Methyltransferase
JOHLMJPM_01551 5.8e-29
JOHLMJPM_01552 5.6e-270 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
JOHLMJPM_01553 2.1e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
JOHLMJPM_01554 5.5e-16 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
JOHLMJPM_01555 3.9e-108 cutC P Participates in the control of copper homeostasis
JOHLMJPM_01556 1.6e-203 XK27_05220 S AI-2E family transporter
JOHLMJPM_01557 4.8e-162 rrmA 2.1.1.187 H Methyltransferase
JOHLMJPM_01558 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
JOHLMJPM_01559 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
JOHLMJPM_01560 2.2e-12 S Protein of unknown function (DUF4044)
JOHLMJPM_01561 7.5e-61 S Protein of unknown function (DUF3397)
JOHLMJPM_01562 2e-79 mraZ K Belongs to the MraZ family
JOHLMJPM_01563 2.6e-177 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
JOHLMJPM_01564 7.6e-62 ftsL D Cell division protein FtsL
JOHLMJPM_01565 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
JOHLMJPM_01566 1.9e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JOHLMJPM_01567 1.1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JOHLMJPM_01568 1.1e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JOHLMJPM_01569 1.8e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
JOHLMJPM_01570 2e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
JOHLMJPM_01571 1.1e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JOHLMJPM_01572 1.7e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
JOHLMJPM_01573 4.1e-41 yggT S YGGT family
JOHLMJPM_01574 1.5e-146 ylmH S S4 domain protein
JOHLMJPM_01575 3.3e-92 divIVA D DivIVA domain protein
JOHLMJPM_01576 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JOHLMJPM_01577 2.2e-34 cspA K Cold shock protein
JOHLMJPM_01578 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
JOHLMJPM_01579 5.2e-31
JOHLMJPM_01580 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JOHLMJPM_01581 1.4e-223 iscS 2.8.1.7 E Aminotransferase class V
JOHLMJPM_01582 1.5e-58 XK27_04120 S Putative amino acid metabolism
JOHLMJPM_01583 6.1e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
JOHLMJPM_01584 3.5e-120 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
JOHLMJPM_01585 7.3e-121 S Repeat protein
JOHLMJPM_01586 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
JOHLMJPM_01587 1.4e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JOHLMJPM_01588 1.2e-126 yoaK S Protein of unknown function (DUF1275)
JOHLMJPM_01589 2.5e-121 yecS E ABC transporter permease
JOHLMJPM_01590 1.3e-159 yckB ET Belongs to the bacterial solute-binding protein 3 family
JOHLMJPM_01591 1.2e-280 nylA 3.5.1.4 J Belongs to the amidase family
JOHLMJPM_01592 1.5e-308 E ABC transporter, substratebinding protein
JOHLMJPM_01593 9e-159 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JOHLMJPM_01594 1.1e-189 yghZ C Aldo keto reductase family protein
JOHLMJPM_01595 3.6e-185 rbsR K helix_turn _helix lactose operon repressor
JOHLMJPM_01596 2.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JOHLMJPM_01597 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JOHLMJPM_01598 2.6e-171 ykfC 3.4.14.13 M NlpC/P60 family
JOHLMJPM_01599 2.3e-166 ypuA S Protein of unknown function (DUF1002)
JOHLMJPM_01600 2.5e-119 mltD CBM50 M NlpC P60 family protein
JOHLMJPM_01601 1.3e-28
JOHLMJPM_01602 5.7e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
JOHLMJPM_01603 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOHLMJPM_01604 1.2e-32 ykzG S Belongs to the UPF0356 family
JOHLMJPM_01605 6.2e-69
JOHLMJPM_01606 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
JOHLMJPM_01607 7e-214 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
JOHLMJPM_01608 2.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
JOHLMJPM_01609 2.9e-206 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
JOHLMJPM_01610 2e-269 lpdA 1.8.1.4 C Dehydrogenase
JOHLMJPM_01611 7.1e-164 1.1.1.27 C L-malate dehydrogenase activity
JOHLMJPM_01612 7.9e-45 yktA S Belongs to the UPF0223 family
JOHLMJPM_01613 1.6e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
JOHLMJPM_01614 0.0 typA T GTP-binding protein TypA
JOHLMJPM_01615 1.9e-209 ftsW D Belongs to the SEDS family
JOHLMJPM_01616 4.4e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
JOHLMJPM_01617 2.2e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
JOHLMJPM_01618 7.3e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JOHLMJPM_01619 3e-198 ylbL T Belongs to the peptidase S16 family
JOHLMJPM_01620 9.7e-121 comEA L Competence protein ComEA
JOHLMJPM_01621 4.4e-88 comEB 3.5.4.12 F ComE operon protein 2
JOHLMJPM_01622 0.0 comEC S Competence protein ComEC
JOHLMJPM_01623 1.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
JOHLMJPM_01624 2.1e-33 rpsT J Binds directly to 16S ribosomal RNA
JOHLMJPM_01625 1.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JOHLMJPM_01626 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JOHLMJPM_01627 1.1e-167 S Tetratricopeptide repeat
JOHLMJPM_01628 1.9e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JOHLMJPM_01629 2.2e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
JOHLMJPM_01630 6.9e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JOHLMJPM_01631 6.6e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
JOHLMJPM_01632 3.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
JOHLMJPM_01633 1.1e-15
JOHLMJPM_01634 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
JOHLMJPM_01635 3.3e-247 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JOHLMJPM_01636 6.2e-105
JOHLMJPM_01637 3.8e-28
JOHLMJPM_01638 5.7e-180 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
JOHLMJPM_01639 2.1e-56 yrvD S Pfam:DUF1049
JOHLMJPM_01640 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
JOHLMJPM_01641 3.2e-92 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JOHLMJPM_01642 1.1e-77 T Universal stress protein family
JOHLMJPM_01644 3.9e-74
JOHLMJPM_01645 2.2e-165 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
JOHLMJPM_01646 1.3e-69 S MTH538 TIR-like domain (DUF1863)
JOHLMJPM_01650 1.6e-82 ndk 2.7.4.6 F Belongs to the NDK family
JOHLMJPM_01651 3.4e-25 KT PspC domain
JOHLMJPM_01652 5.3e-124 G phosphoglycerate mutase
JOHLMJPM_01653 4.3e-166 S Polyphosphate nucleotide phosphotransferase, PPK2 family
JOHLMJPM_01654 6.5e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
JOHLMJPM_01655 4.1e-80
JOHLMJPM_01656 4.2e-77 F nucleoside 2-deoxyribosyltransferase
JOHLMJPM_01657 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JOHLMJPM_01658 1.8e-37 ynzC S UPF0291 protein
JOHLMJPM_01659 1.6e-32 yneF S Uncharacterised protein family (UPF0154)
JOHLMJPM_01660 9.9e-287 mdlA V ABC transporter
JOHLMJPM_01661 0.0 mdlB V ABC transporter
JOHLMJPM_01662 4e-121 plsC 2.3.1.51 I Acyltransferase
JOHLMJPM_01663 2.1e-137 yabB 2.1.1.223 L Methyltransferase small domain
JOHLMJPM_01664 3.4e-45 yazA L GIY-YIG catalytic domain protein
JOHLMJPM_01665 4.7e-185 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOHLMJPM_01666 2.2e-136 S Haloacid dehalogenase-like hydrolase
JOHLMJPM_01667 3.8e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
JOHLMJPM_01668 1.9e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JOHLMJPM_01669 1.7e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
JOHLMJPM_01670 2.4e-85 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
JOHLMJPM_01671 3.2e-74
JOHLMJPM_01672 2.1e-148 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JOHLMJPM_01673 5.3e-139 cdsA 2.7.7.41 I Belongs to the CDS family
JOHLMJPM_01674 5.9e-233 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
JOHLMJPM_01675 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
JOHLMJPM_01676 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JOHLMJPM_01677 1.4e-38
JOHLMJPM_01678 1.8e-81 rimP J Required for maturation of 30S ribosomal subunits
JOHLMJPM_01679 1.2e-190 nusA K Participates in both transcription termination and antitermination
JOHLMJPM_01680 2.3e-47 ylxR K Protein of unknown function (DUF448)
JOHLMJPM_01681 1.4e-44 ylxQ J ribosomal protein
JOHLMJPM_01682 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JOHLMJPM_01683 9.4e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JOHLMJPM_01684 6.7e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JOHLMJPM_01685 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
JOHLMJPM_01686 7.8e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
JOHLMJPM_01687 1.8e-83 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JOHLMJPM_01688 0.0 dnaK O Heat shock 70 kDa protein
JOHLMJPM_01689 1.3e-178 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
JOHLMJPM_01690 1.7e-17 dltX S D-Ala-teichoic acid biosynthesis protein
JOHLMJPM_01691 1.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOHLMJPM_01692 3.8e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
JOHLMJPM_01693 5.2e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
JOHLMJPM_01694 2.9e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
JOHLMJPM_01695 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
JOHLMJPM_01696 4.3e-135 3.6.4.12 L Belongs to the 'phage' integrase family
JOHLMJPM_01699 1.7e-73 S Domain of unknown function DUF1829
JOHLMJPM_01700 1.2e-44
JOHLMJPM_01701 5.6e-34
JOHLMJPM_01702 3.2e-17
JOHLMJPM_01703 1.6e-16
JOHLMJPM_01706 7.1e-17
JOHLMJPM_01708 4.5e-24 S Domain of unknown function (DUF4145)
JOHLMJPM_01709 4.2e-71 S Pfam:Peptidase_M78
JOHLMJPM_01710 1.7e-26 K Helix-turn-helix domain
JOHLMJPM_01714 3.9e-15 S Hypothetical protein (DUF2513)
JOHLMJPM_01716 1.5e-17 K Cro/C1-type HTH DNA-binding domain
JOHLMJPM_01721 2.7e-07
JOHLMJPM_01726 1.4e-84 recT L RecT family
JOHLMJPM_01727 1e-44 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
JOHLMJPM_01728 1e-90 3.1.3.16 L DnaD domain protein
JOHLMJPM_01729 1.4e-63 S ORF6C domain
JOHLMJPM_01730 2.6e-42 S Endodeoxyribonuclease RusA
JOHLMJPM_01732 6e-39 S DNA N-6-adenine-methyltransferase (Dam)
JOHLMJPM_01735 2.5e-35 S YopX protein
JOHLMJPM_01736 2.7e-08
JOHLMJPM_01737 9.7e-12
JOHLMJPM_01741 5.7e-11
JOHLMJPM_01744 3.1e-107 S DNA packaging
JOHLMJPM_01745 3.8e-166 S Phage terminase large subunit
JOHLMJPM_01746 9.4e-261 S Protein of unknown function (DUF1073)
JOHLMJPM_01747 2.5e-131 S Phage Mu protein F like protein
JOHLMJPM_01749 2.6e-176 S Uncharacterized protein conserved in bacteria (DUF2213)
JOHLMJPM_01750 4.1e-75
JOHLMJPM_01751 3.2e-161 S Uncharacterized protein conserved in bacteria (DUF2184)
JOHLMJPM_01752 1.2e-58
JOHLMJPM_01753 7.7e-52 S Protein of unknown function (DUF4054)
JOHLMJPM_01754 8.4e-97
JOHLMJPM_01755 4.1e-65
JOHLMJPM_01756 1.7e-60
JOHLMJPM_01757 9e-139 S Protein of unknown function (DUF3383)
JOHLMJPM_01758 2.6e-70
JOHLMJPM_01759 1.1e-62
JOHLMJPM_01761 1.9e-145 M Phage tail tape measure protein TP901
JOHLMJPM_01762 1.5e-107 S N-acetylmuramoyl-L-alanine amidase activity
JOHLMJPM_01763 6e-67
JOHLMJPM_01764 3.8e-208
JOHLMJPM_01765 3.5e-55
JOHLMJPM_01766 4.7e-11 S Protein of unknown function (DUF2634)
JOHLMJPM_01767 2.2e-181 S Baseplate J-like protein
JOHLMJPM_01768 3.2e-73
JOHLMJPM_01769 1.3e-32
JOHLMJPM_01771 3.3e-34
JOHLMJPM_01773 1.7e-27
JOHLMJPM_01776 2.5e-184 M Glycosyl hydrolases family 25
JOHLMJPM_01777 3.7e-25 S Transglycosylase associated protein
JOHLMJPM_01778 5.5e-71
JOHLMJPM_01779 1.6e-22
JOHLMJPM_01780 1.2e-65 asp S Asp23 family, cell envelope-related function
JOHLMJPM_01781 1e-53 asp2 S Asp23 family, cell envelope-related function
JOHLMJPM_01782 8.1e-09
JOHLMJPM_01783 4.3e-135 3.6.4.12 L Belongs to the 'phage' integrase family
JOHLMJPM_01786 1.7e-73 S Domain of unknown function DUF1829
JOHLMJPM_01787 1.2e-44
JOHLMJPM_01788 5.6e-34
JOHLMJPM_01789 3.2e-17
JOHLMJPM_01790 1.6e-16
JOHLMJPM_01793 7.1e-17
JOHLMJPM_01795 4.5e-24 S Domain of unknown function (DUF4145)
JOHLMJPM_01796 4.2e-71 S Pfam:Peptidase_M78
JOHLMJPM_01797 1.7e-26 K Helix-turn-helix domain
JOHLMJPM_01801 3.9e-15 S Hypothetical protein (DUF2513)
JOHLMJPM_01803 9.1e-175 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
JOHLMJPM_01804 8.2e-38 asnB 6.3.5.4 E Protein of unknown function (DUF3923)
JOHLMJPM_01807 8.2e-38 asnB 6.3.5.4 E Protein of unknown function (DUF3923)
JOHLMJPM_01809 9.8e-214 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
JOHLMJPM_01811 3.3e-42
JOHLMJPM_01813 2.8e-63
JOHLMJPM_01814 9.1e-28 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
JOHLMJPM_01815 1.2e-54
JOHLMJPM_01816 9.7e-180 prmA J Ribosomal protein L11 methyltransferase
JOHLMJPM_01817 3.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
JOHLMJPM_01818 2.7e-60
JOHLMJPM_01819 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JOHLMJPM_01820 3.6e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
JOHLMJPM_01821 8.7e-116 3.1.3.18 S HAD-hyrolase-like
JOHLMJPM_01822 3.5e-165 yniA G Fructosamine kinase
JOHLMJPM_01823 5.8e-160 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JOHLMJPM_01824 6.1e-99
JOHLMJPM_01825 8.7e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
JOHLMJPM_01826 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
JOHLMJPM_01827 4.4e-97 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JOHLMJPM_01828 1.7e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOHLMJPM_01829 1.5e-190 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
JOHLMJPM_01830 8e-151 tagG U Transport permease protein
JOHLMJPM_01831 1.8e-242 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
JOHLMJPM_01832 4.6e-174 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JOHLMJPM_01833 1.3e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
JOHLMJPM_01834 1.3e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
JOHLMJPM_01835 2e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
JOHLMJPM_01836 3.4e-67 hxlR K Transcriptional regulator, HxlR family
JOHLMJPM_01837 7e-72 yqeY S YqeY-like protein
JOHLMJPM_01838 1.4e-181 phoH T phosphate starvation-inducible protein PhoH
JOHLMJPM_01839 8.5e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JOHLMJPM_01840 3.4e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
JOHLMJPM_01841 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JOHLMJPM_01842 8.6e-150 recO L Involved in DNA repair and RecF pathway recombination
JOHLMJPM_01843 1.5e-177 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
JOHLMJPM_01844 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
JOHLMJPM_01845 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
JOHLMJPM_01846 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
JOHLMJPM_01847 1.6e-88 K Transcriptional regulator
JOHLMJPM_01848 0.0 ydgH S MMPL family
JOHLMJPM_01849 2.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
JOHLMJPM_01850 3.1e-155 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JOHLMJPM_01851 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
JOHLMJPM_01852 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
JOHLMJPM_01853 0.0 dnaE 2.7.7.7 L DNA polymerase
JOHLMJPM_01854 2.5e-127 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
JOHLMJPM_01855 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
JOHLMJPM_01856 9.3e-169 cvfB S S1 domain
JOHLMJPM_01857 9.8e-166 xerD D recombinase XerD
JOHLMJPM_01858 3.1e-71 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
JOHLMJPM_01859 7.4e-133 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JOHLMJPM_01860 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JOHLMJPM_01861 2.7e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
JOHLMJPM_01862 6.5e-94 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
JOHLMJPM_01863 4.1e-184 ypbB 5.1.3.1 S Helix-turn-helix domain
JOHLMJPM_01864 9.8e-253 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
JOHLMJPM_01865 8e-26 M Lysin motif
JOHLMJPM_01866 6.4e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
JOHLMJPM_01867 1.1e-210 rpsA 1.17.7.4 J Ribosomal protein S1
JOHLMJPM_01868 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
JOHLMJPM_01869 1.5e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
JOHLMJPM_01870 6.3e-235 S Tetratricopeptide repeat protein
JOHLMJPM_01871 1.3e-171 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOHLMJPM_01872 1.1e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
JOHLMJPM_01873 0.0 yfmR S ABC transporter, ATP-binding protein
JOHLMJPM_01874 7.4e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JOHLMJPM_01875 8.8e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JOHLMJPM_01876 2.8e-114 hlyIII S protein, hemolysin III
JOHLMJPM_01877 3.6e-149 DegV S EDD domain protein, DegV family
JOHLMJPM_01878 1.2e-166 ypmR E GDSL-like Lipase/Acylhydrolase
JOHLMJPM_01879 6.5e-105 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
JOHLMJPM_01880 5.8e-35 yozE S Belongs to the UPF0346 family
JOHLMJPM_01881 5.7e-129
JOHLMJPM_01882 1.4e-175 L Integrase core domain
JOHLMJPM_01883 1.5e-141 U Binding-protein-dependent transport system inner membrane component
JOHLMJPM_01884 2.6e-152 U Binding-protein-dependent transport system inner membrane component
JOHLMJPM_01885 1.2e-249 G Bacterial extracellular solute-binding protein
JOHLMJPM_01886 1.9e-214 P Belongs to the ABC transporter superfamily
JOHLMJPM_01887 3.4e-172 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
JOHLMJPM_01888 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
JOHLMJPM_01889 9.8e-71 K Transcriptional regulator
JOHLMJPM_01890 1.9e-94 qorB 1.6.5.2 GM NmrA-like family
JOHLMJPM_01891 1.7e-211 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JOHLMJPM_01892 5.8e-76 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JOHLMJPM_01894 1.1e-141 K Helix-turn-helix domain
JOHLMJPM_01895 4.7e-168
JOHLMJPM_01896 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
JOHLMJPM_01897 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
JOHLMJPM_01898 9.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
JOHLMJPM_01899 6.2e-185 xynD 3.5.1.104 G polysaccharide deacetylase
JOHLMJPM_01900 1.3e-58
JOHLMJPM_01901 4.6e-103 GM NAD(P)H-binding
JOHLMJPM_01902 5.7e-183 iolS C Aldo keto reductase
JOHLMJPM_01903 5.9e-228 pbuG S permease
JOHLMJPM_01904 1.7e-93 K helix_turn_helix multiple antibiotic resistance protein
JOHLMJPM_01905 2.7e-166 drrA V ABC transporter
JOHLMJPM_01906 7e-120 drrB U ABC-2 type transporter
JOHLMJPM_01907 1.5e-169 2.5.1.74 H UbiA prenyltransferase family
JOHLMJPM_01908 0.0 S Bacterial membrane protein YfhO
JOHLMJPM_01909 1.2e-86 ccl S QueT transporter
JOHLMJPM_01911 2.2e-32
JOHLMJPM_01912 0.0 S Predicted membrane protein (DUF2207)
JOHLMJPM_01913 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
JOHLMJPM_01914 2.7e-282 xynT G MFS/sugar transport protein
JOHLMJPM_01915 6.2e-152 rhaS2 K Transcriptional regulator, AraC family
JOHLMJPM_01916 9.7e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JOHLMJPM_01917 5.2e-22
JOHLMJPM_01918 4.1e-150 F DNA/RNA non-specific endonuclease
JOHLMJPM_01919 4.5e-89
JOHLMJPM_01922 1.2e-51
JOHLMJPM_01923 6.3e-114 L haloacid dehalogenase-like hydrolase
JOHLMJPM_01924 1.5e-255 pepC 3.4.22.40 E aminopeptidase
JOHLMJPM_01925 1.6e-79 K helix_turn_helix multiple antibiotic resistance protein
JOHLMJPM_01926 4.2e-109 lepB 3.4.21.89 U Belongs to the peptidase S26 family
JOHLMJPM_01927 5.3e-218 tcaB EGP Major facilitator Superfamily
JOHLMJPM_01928 1.6e-227 S module of peptide synthetase
JOHLMJPM_01929 1.2e-91 ykhA 3.1.2.20 I Thioesterase superfamily
JOHLMJPM_01930 1.4e-98 J Acetyltransferase (GNAT) domain
JOHLMJPM_01931 5.1e-116 ywnB S NAD(P)H-binding
JOHLMJPM_01932 5.5e-245 brnQ U Component of the transport system for branched-chain amino acids
JOHLMJPM_01933 4.3e-37
JOHLMJPM_01934 2.6e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
JOHLMJPM_01935 1e-37
JOHLMJPM_01936 5.2e-55
JOHLMJPM_01937 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
JOHLMJPM_01938 3.2e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JOHLMJPM_01939 5.9e-111 jag S R3H domain protein
JOHLMJPM_01940 1e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOHLMJPM_01941 3.2e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
JOHLMJPM_01942 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
JOHLMJPM_01943 1.7e-257 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JOHLMJPM_01944 2.9e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
JOHLMJPM_01945 2e-35 yaaA S S4 domain protein YaaA
JOHLMJPM_01946 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JOHLMJPM_01947 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOHLMJPM_01948 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JOHLMJPM_01949 1.9e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
JOHLMJPM_01950 3e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
JOHLMJPM_01951 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JOHLMJPM_01952 4.7e-232 Q Imidazolonepropionase and related amidohydrolases
JOHLMJPM_01953 4e-303 E ABC transporter, substratebinding protein
JOHLMJPM_01954 2.4e-144
JOHLMJPM_01955 9.7e-230 Q Imidazolonepropionase and related amidohydrolases
JOHLMJPM_01956 2.8e-304 E ABC transporter, substratebinding protein
JOHLMJPM_01957 1e-99 K Bacterial regulatory proteins, tetR family
JOHLMJPM_01958 1e-38 S response to heat
JOHLMJPM_01959 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
JOHLMJPM_01960 7.2e-64 rplI J Binds to the 23S rRNA
JOHLMJPM_01962 6e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
JOHLMJPM_01963 3.8e-101 S NADPH-dependent FMN reductase
JOHLMJPM_01964 1.1e-212 yttB EGP Major facilitator Superfamily
JOHLMJPM_01965 1.1e-22
JOHLMJPM_01966 2.8e-304 E ABC transporter, substratebinding protein
JOHLMJPM_01967 1.3e-38
JOHLMJPM_01968 1.1e-130 E Matrixin
JOHLMJPM_01970 5.7e-132 K response regulator
JOHLMJPM_01971 0.0 vicK 2.7.13.3 T Histidine kinase
JOHLMJPM_01972 1.1e-239 yycH S YycH protein
JOHLMJPM_01973 2.6e-152 yycI S YycH protein
JOHLMJPM_01974 3.4e-157 vicX 3.1.26.11 S domain protein
JOHLMJPM_01975 4e-195 htrA 3.4.21.107 O serine protease
JOHLMJPM_01976 7.3e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JOHLMJPM_01977 5.3e-19 S Protein of unknown function (DUF2971)
JOHLMJPM_01978 1.4e-175 L Integrase core domain
JOHLMJPM_01979 9.9e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JOHLMJPM_01980 1.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
JOHLMJPM_01981 4.7e-155 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
JOHLMJPM_01982 6.3e-276 pipD E Dipeptidase
JOHLMJPM_01983 7.7e-280 yjeM E Amino Acid
JOHLMJPM_01984 2.2e-148 K Helix-turn-helix
JOHLMJPM_01985 1.5e-10 K Bacterial regulatory proteins, tetR family
JOHLMJPM_01986 6.2e-70
JOHLMJPM_01987 2.1e-102 rimL J Acetyltransferase (GNAT) domain
JOHLMJPM_01988 4.8e-295 katA 1.11.1.6 C Belongs to the catalase family
JOHLMJPM_01989 4e-198 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JOHLMJPM_01990 8.9e-192 C Aldo/keto reductase family
JOHLMJPM_01991 1.6e-26 adhR K MerR, DNA binding
JOHLMJPM_01992 1.7e-148 K LysR substrate binding domain
JOHLMJPM_01993 2.3e-209 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
JOHLMJPM_01994 1.4e-118 ydeA 3.5.1.124 S DJ-1/PfpI family
JOHLMJPM_01997 1.1e-178 S Cysteine-rich secretory protein family
JOHLMJPM_01998 2.4e-50 N PFAM Uncharacterised protein family UPF0150
JOHLMJPM_01999 8.7e-75 K LytTr DNA-binding domain
JOHLMJPM_02000 6.1e-79 S Protein of unknown function (DUF3021)
JOHLMJPM_02001 1.1e-92 entB 3.5.1.19 Q Isochorismatase family
JOHLMJPM_02002 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
JOHLMJPM_02003 2.2e-85 bioY S BioY family
JOHLMJPM_02004 8.4e-145 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
JOHLMJPM_02005 5.3e-128 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
JOHLMJPM_02006 5.9e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
JOHLMJPM_02007 4.2e-155 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JOHLMJPM_02008 1.2e-266 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
JOHLMJPM_02009 3.8e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
JOHLMJPM_02010 3e-72 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
JOHLMJPM_02011 1.1e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
JOHLMJPM_02012 3.2e-122 IQ reductase
JOHLMJPM_02013 2.2e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
JOHLMJPM_02014 2e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOHLMJPM_02015 1.7e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JOHLMJPM_02016 4.3e-80 marR K Transcriptional regulator
JOHLMJPM_02017 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
JOHLMJPM_02018 2.7e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
JOHLMJPM_02019 2.4e-144 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
JOHLMJPM_02020 4.1e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JOHLMJPM_02021 1.9e-40 ylqC S Belongs to the UPF0109 family
JOHLMJPM_02022 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
JOHLMJPM_02023 2.1e-48
JOHLMJPM_02024 4.5e-252 S Putative metallopeptidase domain
JOHLMJPM_02025 1.8e-215 3.1.3.1 S associated with various cellular activities
JOHLMJPM_02026 0.0 pacL 3.6.3.8 P P-type ATPase
JOHLMJPM_02027 6.4e-207 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JOHLMJPM_02028 2.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
JOHLMJPM_02029 3.6e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
JOHLMJPM_02030 0.0 smc D Required for chromosome condensation and partitioning
JOHLMJPM_02031 2.8e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
JOHLMJPM_02032 6.4e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
JOHLMJPM_02033 4.7e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
JOHLMJPM_02034 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JOHLMJPM_02035 0.0 yloV S DAK2 domain fusion protein YloV
JOHLMJPM_02036 5.2e-57 asp S Asp23 family, cell envelope-related function
JOHLMJPM_02037 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
JOHLMJPM_02038 4.7e-128 thiN 2.7.6.2 H thiamine pyrophosphokinase
JOHLMJPM_02039 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
JOHLMJPM_02040 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
JOHLMJPM_02041 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
JOHLMJPM_02042 7.7e-132 stp 3.1.3.16 T phosphatase
JOHLMJPM_02043 1.6e-228 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JOHLMJPM_02044 1.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JOHLMJPM_02045 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JOHLMJPM_02046 3.7e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JOHLMJPM_02047 4.9e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
JOHLMJPM_02048 3.3e-104 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
JOHLMJPM_02049 3.4e-52
JOHLMJPM_02051 2.1e-310 recN L May be involved in recombinational repair of damaged DNA
JOHLMJPM_02052 3.7e-76 argR K Regulates arginine biosynthesis genes
JOHLMJPM_02053 2.6e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
JOHLMJPM_02054 7.6e-166 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
JOHLMJPM_02055 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOHLMJPM_02056 2.5e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
JOHLMJPM_02057 6.2e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JOHLMJPM_02058 7.2e-74 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JOHLMJPM_02059 4.8e-73 yqhY S Asp23 family, cell envelope-related function
JOHLMJPM_02060 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JOHLMJPM_02061 2.8e-191 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JOHLMJPM_02062 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
JOHLMJPM_02063 2.2e-57 ysxB J Cysteine protease Prp
JOHLMJPM_02064 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
JOHLMJPM_02065 4.1e-95 K Transcriptional regulator
JOHLMJPM_02066 2.2e-96 dut S Protein conserved in bacteria
JOHLMJPM_02067 1.8e-178
JOHLMJPM_02068 8.1e-157
JOHLMJPM_02069 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
JOHLMJPM_02070 2.1e-64 glnR K Transcriptional regulator
JOHLMJPM_02071 1.2e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JOHLMJPM_02072 1.9e-141 glpQ 3.1.4.46 C phosphodiesterase
JOHLMJPM_02073 3.1e-23 WQ51_02665 S Protein of unknown function (DUF3042)
JOHLMJPM_02074 2.1e-70 yqhL P Rhodanese-like protein
JOHLMJPM_02075 6.9e-181 glk 2.7.1.2 G Glucokinase
JOHLMJPM_02076 9.3e-36 yqgQ S Bacterial protein of unknown function (DUF910)
JOHLMJPM_02077 4e-119 gluP 3.4.21.105 S Peptidase, S54 family
JOHLMJPM_02078 1.4e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JOHLMJPM_02079 2.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
JOHLMJPM_02080 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
JOHLMJPM_02081 6.5e-28 CP_0775 S Domain of unknown function (DUF378)
JOHLMJPM_02082 0.0 S membrane
JOHLMJPM_02083 1.7e-56 yneR S Belongs to the HesB IscA family
JOHLMJPM_02084 6.3e-71 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
JOHLMJPM_02085 1e-119 udk 2.7.1.48 F Cytidine monophosphokinase
JOHLMJPM_02086 1.7e-207 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JOHLMJPM_02087 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOHLMJPM_02088 5.8e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JOHLMJPM_02089 3.9e-68 yodB K Transcriptional regulator, HxlR family
JOHLMJPM_02090 4e-92 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
JOHLMJPM_02091 9.4e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JOHLMJPM_02092 8.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
JOHLMJPM_02093 3.1e-135 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
JOHLMJPM_02094 9.2e-71 S Protein of unknown function (DUF1093)
JOHLMJPM_02095 1.1e-292 arlS 2.7.13.3 T Histidine kinase
JOHLMJPM_02096 2.8e-120 K response regulator
JOHLMJPM_02097 1.9e-194 adhP 1.1.1.1 C alcohol dehydrogenase
JOHLMJPM_02098 1.5e-115 zmp3 O Zinc-dependent metalloprotease
JOHLMJPM_02099 2.3e-53 K Transcriptional regulator, ArsR family
JOHLMJPM_02100 3.4e-149 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
JOHLMJPM_02101 6.9e-29 rpmF J Belongs to the bacterial ribosomal protein bL32 family
JOHLMJPM_02102 8.6e-96 yceD S Uncharacterized ACR, COG1399
JOHLMJPM_02103 6.3e-218 ylbM S Belongs to the UPF0348 family
JOHLMJPM_02104 1.5e-140 yqeM Q Methyltransferase
JOHLMJPM_02105 5.4e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
JOHLMJPM_02106 3.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
JOHLMJPM_02107 5.9e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JOHLMJPM_02108 1.3e-48 yhbY J RNA-binding protein
JOHLMJPM_02109 8.5e-223 yqeH S Ribosome biogenesis GTPase YqeH
JOHLMJPM_02110 3.2e-103 yqeG S HAD phosphatase, family IIIA
JOHLMJPM_02111 3.7e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JOHLMJPM_02112 5.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
JOHLMJPM_02113 4.4e-79 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JOHLMJPM_02114 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JOHLMJPM_02115 1.3e-165 dnaI L Primosomal protein DnaI
JOHLMJPM_02116 4.9e-249 dnaB L replication initiation and membrane attachment
JOHLMJPM_02117 7.8e-88 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JOHLMJPM_02118 2.8e-111 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JOHLMJPM_02119 2.3e-164 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
JOHLMJPM_02120 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JOHLMJPM_02121 9e-264 guaD 3.5.4.3 F Amidohydrolase family
JOHLMJPM_02122 8.5e-238 F Permease
JOHLMJPM_02123 7.1e-119 ybhL S Belongs to the BI1 family
JOHLMJPM_02124 6.2e-134 pnuC H nicotinamide mononucleotide transporter
JOHLMJPM_02125 4.3e-258 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
JOHLMJPM_02126 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
JOHLMJPM_02127 1.4e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
JOHLMJPM_02128 4e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
JOHLMJPM_02129 2e-55 ytzB S Small secreted protein
JOHLMJPM_02130 1.8e-248 cycA E Amino acid permease
JOHLMJPM_02131 1.2e-202 ald 1.4.1.1 C Belongs to the AlaDH PNT family
JOHLMJPM_02132 8.2e-85 uspA T Belongs to the universal stress protein A family
JOHLMJPM_02133 2.4e-272 pepV 3.5.1.18 E dipeptidase PepV
JOHLMJPM_02134 1.3e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JOHLMJPM_02135 1.3e-125 rluB 5.4.99.19, 5.4.99.20, 5.4.99.21, 5.4.99.22 J pseudouridine synthase activity
JOHLMJPM_02136 8.8e-298 ytgP S Polysaccharide biosynthesis protein
JOHLMJPM_02137 4.4e-52
JOHLMJPM_02138 4.8e-145 S NADPH-dependent FMN reductase
JOHLMJPM_02139 2.2e-122 P ABC-type multidrug transport system ATPase component
JOHLMJPM_02140 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
JOHLMJPM_02141 1.3e-116 pgpB1 3.6.1.27 I Acid phosphatase homologues
JOHLMJPM_02142 3.7e-102 ytqB J Putative rRNA methylase
JOHLMJPM_02144 2.2e-251 pgaC GT2 M Glycosyl transferase
JOHLMJPM_02145 2.6e-91
JOHLMJPM_02146 1.2e-83 T EAL domain
JOHLMJPM_02147 1.7e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
JOHLMJPM_02148 1e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
JOHLMJPM_02149 8.4e-139 yhfI S Metallo-beta-lactamase superfamily
JOHLMJPM_02150 1.8e-92 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
JOHLMJPM_02151 1.9e-233 N Uncharacterized conserved protein (DUF2075)
JOHLMJPM_02161 1.2e-07
JOHLMJPM_02170 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
JOHLMJPM_02171 4.3e-36 ykuJ S Protein of unknown function (DUF1797)
JOHLMJPM_02172 1.9e-184 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
JOHLMJPM_02173 3.6e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
JOHLMJPM_02174 2.7e-224 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
JOHLMJPM_02175 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JOHLMJPM_02176 7.2e-40 ptsH G phosphocarrier protein HPR
JOHLMJPM_02177 3.9e-30
JOHLMJPM_02178 0.0 clpE O Belongs to the ClpA ClpB family
JOHLMJPM_02179 1.1e-214 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
JOHLMJPM_02180 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
JOHLMJPM_02181 9.2e-283 pipD E Dipeptidase
JOHLMJPM_02182 7.4e-258 nox 1.6.3.4 C NADH oxidase
JOHLMJPM_02183 1.6e-61 XK27_00720 S Leucine-rich repeat (LRR) protein
JOHLMJPM_02184 5.5e-286 XK27_00720 S Leucine-rich repeat (LRR) protein
JOHLMJPM_02185 1.3e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JOHLMJPM_02186 3.1e-90
JOHLMJPM_02187 0.0 2.7.8.12 M glycerophosphotransferase
JOHLMJPM_02188 3.7e-157
JOHLMJPM_02189 2.6e-76 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
JOHLMJPM_02190 1.4e-180 yueF S AI-2E family transporter
JOHLMJPM_02191 4.4e-108 ygaC J Belongs to the UPF0374 family
JOHLMJPM_02192 5.6e-39 S Bacteriocin-protection, YdeI or OmpD-Associated
JOHLMJPM_02193 5e-218 pbpX2 V Beta-lactamase
JOHLMJPM_02194 1.2e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
JOHLMJPM_02195 1e-78 fld C Flavodoxin
JOHLMJPM_02196 9e-159 yihY S Belongs to the UPF0761 family
JOHLMJPM_02197 2.1e-157 S Nuclease-related domain
JOHLMJPM_02198 1.8e-212 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
JOHLMJPM_02199 2.5e-159 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
JOHLMJPM_02200 4.1e-232 gntP EG Gluconate
JOHLMJPM_02201 5.6e-77 T Universal stress protein family
JOHLMJPM_02204 3.5e-212 yfmL 3.6.4.13 L DEAD DEAH box helicase
JOHLMJPM_02205 3.9e-187 mocA S Oxidoreductase
JOHLMJPM_02206 5.7e-64 S Domain of unknown function (DUF4828)
JOHLMJPM_02207 8.7e-147 lys M Glycosyl hydrolases family 25
JOHLMJPM_02208 3.2e-150 gntR K rpiR family
JOHLMJPM_02209 2.1e-304 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
JOHLMJPM_02210 4.3e-213 gntP EG Gluconate
JOHLMJPM_02211 2.8e-233 potE E amino acid
JOHLMJPM_02212 4.3e-250 fucP G Major Facilitator Superfamily
JOHLMJPM_02213 2.5e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
JOHLMJPM_02214 2.4e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
JOHLMJPM_02215 8.7e-240 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
JOHLMJPM_02216 5.2e-173 deoR K sugar-binding domain protein
JOHLMJPM_02217 1.7e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
JOHLMJPM_02218 3.8e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
JOHLMJPM_02219 1.3e-120 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JOHLMJPM_02220 4.6e-38 cro K Helix-turn-helix XRE-family like proteins
JOHLMJPM_02221 1.2e-58 K Helix-turn-helix XRE-family like proteins
JOHLMJPM_02222 1.3e-145 3.1.3.48 T Pfam:Y_phosphatase3C
JOHLMJPM_02223 1.8e-195 C Oxidoreductase
JOHLMJPM_02224 7.8e-55 pduU E BMC
JOHLMJPM_02225 6.3e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOHLMJPM_02226 2.1e-210 pduQ C Iron-containing alcohol dehydrogenase
JOHLMJPM_02227 5.4e-267 pduP 1.2.1.87 C Aldehyde dehydrogenase family
JOHLMJPM_02228 1.4e-81 pduO S Haem-degrading
JOHLMJPM_02229 5.8e-103 pduO 2.5.1.17 S Cobalamin adenosyltransferase
JOHLMJPM_02230 6e-42 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
JOHLMJPM_02231 3e-90 S Putative propanediol utilisation
JOHLMJPM_02232 1.6e-114 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
JOHLMJPM_02233 4.9e-42 pduA_4 CQ BMC
JOHLMJPM_02234 9.7e-83 pduK CQ BMC
JOHLMJPM_02235 6e-58 pduH S Dehydratase medium subunit
JOHLMJPM_02236 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
JOHLMJPM_02237 3e-90 pduE 4.2.1.28 Q Dehydratase small subunit
JOHLMJPM_02238 2e-129 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
JOHLMJPM_02239 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
JOHLMJPM_02240 4.1e-130 pduB E BMC
JOHLMJPM_02241 5.2e-41 pduA_4 CQ BMC
JOHLMJPM_02242 2.8e-207 K helix_turn_helix, arabinose operon control protein
JOHLMJPM_02243 9.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
JOHLMJPM_02244 3.3e-42 eutP E Ethanolamine utilisation - propanediol utilisation
JOHLMJPM_02245 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
JOHLMJPM_02246 5.8e-160 mod 2.1.1.72 L DNA methylase
JOHLMJPM_02247 1.4e-175 L Integrase core domain
JOHLMJPM_02248 5.2e-71 yugI 5.3.1.9 J general stress protein
JOHLMJPM_02249 3.5e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JOHLMJPM_02250 6.1e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
JOHLMJPM_02251 2.9e-122 dedA S SNARE-like domain protein
JOHLMJPM_02252 3.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
JOHLMJPM_02253 1.8e-251 yfnA E Amino Acid
JOHLMJPM_02254 1.7e-268 M domain protein
JOHLMJPM_02255 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
JOHLMJPM_02256 6.9e-89 S WxL domain surface cell wall-binding
JOHLMJPM_02257 7.7e-117 S Protein of unknown function (DUF1461)
JOHLMJPM_02258 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
JOHLMJPM_02259 1.1e-86 yutD S Protein of unknown function (DUF1027)
JOHLMJPM_02260 2.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
JOHLMJPM_02261 5.3e-115 S Calcineurin-like phosphoesterase
JOHLMJPM_02262 8.7e-156 yeaE S Aldo keto
JOHLMJPM_02263 2e-258 cycA E Amino acid permease
JOHLMJPM_02264 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JOHLMJPM_02265 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
JOHLMJPM_02266 1.1e-74
JOHLMJPM_02268 3.4e-82
JOHLMJPM_02269 7.6e-49 comGC U competence protein ComGC
JOHLMJPM_02270 3.1e-170 comGB NU type II secretion system
JOHLMJPM_02271 1.2e-172 comGA NU Type II IV secretion system protein
JOHLMJPM_02272 2.6e-132 yebC K Transcriptional regulatory protein
JOHLMJPM_02273 9.5e-267 glnPH2 P ABC transporter permease
JOHLMJPM_02274 5.7e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JOHLMJPM_02275 2.7e-133
JOHLMJPM_02276 1.6e-180 ccpA K catabolite control protein A
JOHLMJPM_02277 2.7e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
JOHLMJPM_02278 9.5e-43
JOHLMJPM_02279 6.9e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
JOHLMJPM_02280 4.1e-156 ykuT M mechanosensitive ion channel
JOHLMJPM_02281 1.8e-251 U Major Facilitator Superfamily
JOHLMJPM_02282 4.7e-48 K helix_turn_helix, Arsenical Resistance Operon Repressor
JOHLMJPM_02284 4.6e-85 ykuL S (CBS) domain
JOHLMJPM_02285 1.9e-100 S Phosphoesterase
JOHLMJPM_02286 9.6e-109 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JOHLMJPM_02287 2.2e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
JOHLMJPM_02288 7.2e-92 yslB S Protein of unknown function (DUF2507)
JOHLMJPM_02289 2.7e-54 trxA O Belongs to the thioredoxin family
JOHLMJPM_02290 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
JOHLMJPM_02291 6.4e-88 cvpA S Colicin V production protein
JOHLMJPM_02292 1.2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JOHLMJPM_02293 1.6e-51 yrzB S Belongs to the UPF0473 family
JOHLMJPM_02294 1.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JOHLMJPM_02295 6.4e-44 yrzL S Belongs to the UPF0297 family
JOHLMJPM_02296 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JOHLMJPM_02297 6.1e-252 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
JOHLMJPM_02298 4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
JOHLMJPM_02299 3.5e-181 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JOHLMJPM_02300 1.1e-26 yajC U Preprotein translocase
JOHLMJPM_02301 3e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
JOHLMJPM_02302 4.1e-200 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JOHLMJPM_02303 6.5e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
JOHLMJPM_02304 2.8e-108 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
JOHLMJPM_02305 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JOHLMJPM_02306 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JOHLMJPM_02307 1.3e-150 ymdB S YmdB-like protein
JOHLMJPM_02308 4e-223 rny S Endoribonuclease that initiates mRNA decay
JOHLMJPM_02310 4.7e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JOHLMJPM_02311 1.6e-227 cinA 3.5.1.42 S Belongs to the CinA family
JOHLMJPM_02312 1e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JOHLMJPM_02313 2.6e-65 ymfM S Domain of unknown function (DUF4115)
JOHLMJPM_02314 1.2e-246 ymfH S Peptidase M16
JOHLMJPM_02315 3.4e-236 ymfF S Peptidase M16 inactive domain protein
JOHLMJPM_02316 1.3e-159 aatB ET ABC transporter substrate-binding protein
JOHLMJPM_02317 3.5e-93 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
JOHLMJPM_02318 2.5e-110 glnP P ABC transporter permease
JOHLMJPM_02319 4.1e-147 minD D Belongs to the ParA family
JOHLMJPM_02320 2.8e-117 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
JOHLMJPM_02321 3.2e-92 mreD M rod shape-determining protein MreD
JOHLMJPM_02322 9.7e-139 mreC M Involved in formation and maintenance of cell shape
JOHLMJPM_02323 9.6e-162 mreB D cell shape determining protein MreB
JOHLMJPM_02324 5.6e-118 radC L DNA repair protein
JOHLMJPM_02325 2.1e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
JOHLMJPM_02326 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
JOHLMJPM_02327 3.5e-91 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
JOHLMJPM_02328 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JOHLMJPM_02329 3.8e-215 iscS2 2.8.1.7 E Aminotransferase class V
JOHLMJPM_02330 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
JOHLMJPM_02331 2.4e-83 ytsP 1.8.4.14 T GAF domain-containing protein
JOHLMJPM_02332 9.7e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JOHLMJPM_02333 7.1e-61 KLT serine threonine protein kinase
JOHLMJPM_02334 1.3e-113 yktB S Belongs to the UPF0637 family
JOHLMJPM_02335 1.9e-80 yueI S Protein of unknown function (DUF1694)
JOHLMJPM_02336 2.1e-238 rarA L recombination factor protein RarA
JOHLMJPM_02337 3.2e-41
JOHLMJPM_02338 1e-81 usp6 T universal stress protein
JOHLMJPM_02339 7.9e-160 2.3.1.19 K Helix-turn-helix XRE-family like proteins
JOHLMJPM_02340 1.1e-305 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
JOHLMJPM_02341 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
JOHLMJPM_02342 4.2e-178 S Protein of unknown function (DUF2785)
JOHLMJPM_02343 9.3e-142 f42a O Band 7 protein
JOHLMJPM_02344 1.9e-49 gcsH2 E glycine cleavage
JOHLMJPM_02345 1.1e-220 rodA D Belongs to the SEDS family
JOHLMJPM_02346 1.1e-33 S Protein of unknown function (DUF2969)
JOHLMJPM_02347 1.1e-52 yidD S Could be involved in insertion of integral membrane proteins into the membrane
JOHLMJPM_02348 4.6e-180 mbl D Cell shape determining protein MreB Mrl
JOHLMJPM_02349 5.9e-244 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JOHLMJPM_02350 4.3e-33 ywzB S Protein of unknown function (DUF1146)
JOHLMJPM_02351 8.3e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
JOHLMJPM_02352 1.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JOHLMJPM_02353 7.3e-161 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JOHLMJPM_02354 1.7e-287 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JOHLMJPM_02355 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOHLMJPM_02356 1.6e-56 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JOHLMJPM_02357 7.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JOHLMJPM_02358 6.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
JOHLMJPM_02359 8e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JOHLMJPM_02360 5.4e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JOHLMJPM_02361 6.5e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
JOHLMJPM_02362 7.9e-157 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
JOHLMJPM_02363 5.5e-187 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JOHLMJPM_02364 8.5e-110 tdk 2.7.1.21 F thymidine kinase
JOHLMJPM_02365 1.4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
JOHLMJPM_02366 1e-133 cobQ S glutamine amidotransferase
JOHLMJPM_02367 5.5e-197 ampC V Beta-lactamase
JOHLMJPM_02368 0.0 yfiC V ABC transporter
JOHLMJPM_02369 0.0 lmrA V ABC transporter, ATP-binding protein
JOHLMJPM_02370 8.9e-56
JOHLMJPM_02371 8.7e-09
JOHLMJPM_02372 2.5e-152 2.7.7.65 T diguanylate cyclase
JOHLMJPM_02373 6.3e-90 L Transposase and inactivated derivatives, IS30 family
JOHLMJPM_02374 1.1e-17
JOHLMJPM_02375 1.1e-231 3.2.1.96, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
JOHLMJPM_02376 4e-98 1.5.1.3 H RibD C-terminal domain
JOHLMJPM_02377 8.6e-54 S Protein of unknown function (DUF1516)
JOHLMJPM_02378 1.6e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
JOHLMJPM_02379 2.3e-253 yxbA 6.3.1.12 S ATP-grasp enzyme
JOHLMJPM_02380 0.0 asnB 6.3.5.4 E Asparagine synthase
JOHLMJPM_02381 4.9e-120 ntcA2 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
JOHLMJPM_02382 3.1e-275 pipD E Peptidase family C69
JOHLMJPM_02383 1.3e-37
JOHLMJPM_02384 0.0
JOHLMJPM_02387 0.0 uvrA3 L ABC transporter
JOHLMJPM_02388 1.9e-126 L Helix-turn-helix domain
JOHLMJPM_02390 5.1e-47
JOHLMJPM_02391 1.2e-83 V VanZ like family
JOHLMJPM_02392 9.4e-83 ohrR K Transcriptional regulator
JOHLMJPM_02393 2.3e-122 S CAAX protease self-immunity
JOHLMJPM_02394 1.1e-37
JOHLMJPM_02395 5.9e-177 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JOHLMJPM_02396 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
JOHLMJPM_02397 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
JOHLMJPM_02398 1.2e-143 S haloacid dehalogenase-like hydrolase
JOHLMJPM_02399 4.5e-120 dck 2.7.1.74 F Deoxynucleoside kinase
JOHLMJPM_02400 1.8e-56 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
JOHLMJPM_02401 3.9e-260 bmr3 EGP Major facilitator Superfamily
JOHLMJPM_02402 9.8e-214 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JOHLMJPM_02403 1.5e-121
JOHLMJPM_02404 5.3e-62
JOHLMJPM_02405 4.7e-105
JOHLMJPM_02406 2.6e-52 ybjQ S Belongs to the UPF0145 family
JOHLMJPM_02407 3.6e-91 zmp2 O Zinc-dependent metalloprotease
JOHLMJPM_02420 1.4e-175 L Integrase core domain
JOHLMJPM_02421 1.3e-44 pepO 3.4.24.71 O Peptidase family M13
JOHLMJPM_02422 9.5e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
JOHLMJPM_02423 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
JOHLMJPM_02425 3.3e-186 galR K Transcriptional regulator
JOHLMJPM_02426 4.1e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
JOHLMJPM_02427 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
JOHLMJPM_02428 5.1e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JOHLMJPM_02429 5.2e-254 gph G Transporter
JOHLMJPM_02430 2.4e-37
JOHLMJPM_02431 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
JOHLMJPM_02432 1.4e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
JOHLMJPM_02433 2.2e-207 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
JOHLMJPM_02434 1.1e-144 etfB C Electron transfer flavoprotein domain
JOHLMJPM_02435 1.3e-176 etfA C Electron transfer flavoprotein FAD-binding domain
JOHLMJPM_02436 3.3e-186 1.1.1.1 C nadph quinone reductase
JOHLMJPM_02437 3.8e-54 K Transcriptional
JOHLMJPM_02438 1.2e-126 hchA 3.5.1.124 S DJ-1/PfpI family
JOHLMJPM_02439 0.0 oppD EP Psort location Cytoplasmic, score
JOHLMJPM_02440 4.3e-82 6.3.3.2 S ASCH
JOHLMJPM_02441 1.4e-246 EGP Major facilitator Superfamily
JOHLMJPM_02442 2.3e-23
JOHLMJPM_02443 1.9e-152 map 3.4.11.18 E Methionine Aminopeptidase
JOHLMJPM_02444 7.4e-140 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
JOHLMJPM_02445 1.4e-158 hipB K Helix-turn-helix
JOHLMJPM_02446 1.3e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
JOHLMJPM_02447 7.5e-70 yeaO S Protein of unknown function, DUF488
JOHLMJPM_02448 5.5e-124 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S HAD-hyrolase-like
JOHLMJPM_02449 7.9e-79 usp1 T Universal stress protein family
JOHLMJPM_02450 6.2e-264 U Belongs to the BCCT transporter (TC 2.A.15) family
JOHLMJPM_02451 9.1e-115 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
JOHLMJPM_02452 2.5e-83 S 3-demethylubiquinone-9 3-methyltransferase
JOHLMJPM_02453 2.6e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JOHLMJPM_02454 4.5e-85
JOHLMJPM_02455 6.4e-240 codA 3.5.4.1 F cytosine deaminase
JOHLMJPM_02456 1.4e-47
JOHLMJPM_02457 1.1e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
JOHLMJPM_02458 5.2e-18
JOHLMJPM_02459 1.1e-124 yrkL S Flavodoxin-like fold
JOHLMJPM_02461 6.2e-30
JOHLMJPM_02463 1.8e-189 L Helix-turn-helix domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)