ORF_ID e_value Gene_name EC_number CAZy COGs Description
EPNMAIED_00001 4e-39 S G5
EPNMAIED_00002 2e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
EPNMAIED_00003 1.1e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EPNMAIED_00004 7.7e-109 S LytR cell envelope-related transcriptional attenuator
EPNMAIED_00005 1.7e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
EPNMAIED_00006 6.3e-122 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
EPNMAIED_00007 0.0 M Conserved repeat domain
EPNMAIED_00008 2.1e-305 murJ KLT MviN-like protein
EPNMAIED_00009 0.0 murJ KLT MviN-like protein
EPNMAIED_00010 4e-13 S Domain of unknown function (DUF4143)
EPNMAIED_00011 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
EPNMAIED_00013 7e-14 S Psort location Extracellular, score 8.82
EPNMAIED_00014 3.2e-73 K FCD
EPNMAIED_00015 6.7e-125 EGP Major facilitator Superfamily
EPNMAIED_00016 0.0 IQ Peptidase S15
EPNMAIED_00017 4.3e-166 potA 3.6.3.30, 3.6.3.31 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
EPNMAIED_00018 1.1e-115 potC U Binding-protein-dependent transport system inner membrane component
EPNMAIED_00019 8.3e-130 U Binding-protein-dependent transport system inner membrane component
EPNMAIED_00020 2.1e-154 potD E Required for the activity of the bacterial periplasmic transport system of putrescine
EPNMAIED_00021 2.7e-146 hisC 2.6.1.9 E Aminotransferase class I and II
EPNMAIED_00022 2.5e-106 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
EPNMAIED_00023 3.1e-181 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
EPNMAIED_00024 1.5e-202 parB K Belongs to the ParB family
EPNMAIED_00025 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
EPNMAIED_00026 1.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
EPNMAIED_00027 3.6e-91 jag S Putative single-stranded nucleic acids-binding domain
EPNMAIED_00028 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
EPNMAIED_00029 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
EPNMAIED_00030 2.9e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EPNMAIED_00031 3e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
EPNMAIED_00032 3.7e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EPNMAIED_00033 6.2e-90 S Protein of unknown function (DUF721)
EPNMAIED_00034 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPNMAIED_00035 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EPNMAIED_00036 8.2e-67 S Transmembrane domain of unknown function (DUF3566)
EPNMAIED_00037 2.1e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
EPNMAIED_00038 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
EPNMAIED_00042 3.7e-101 S Protein of unknown function DUF45
EPNMAIED_00043 9e-189 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
EPNMAIED_00044 1e-240 ytfL P Transporter associated domain
EPNMAIED_00045 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
EPNMAIED_00046 1.1e-38
EPNMAIED_00047 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EPNMAIED_00048 0.0 yjjP S Threonine/Serine exporter, ThrE
EPNMAIED_00049 9.4e-300 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EPNMAIED_00050 2.2e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
EPNMAIED_00051 1.4e-41 S Protein of unknown function (DUF3073)
EPNMAIED_00052 1.7e-63 I Sterol carrier protein
EPNMAIED_00053 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
EPNMAIED_00054 3.4e-35
EPNMAIED_00055 1.4e-147 gluP 3.4.21.105 S Rhomboid family
EPNMAIED_00056 3.3e-240 L ribosomal rna small subunit methyltransferase
EPNMAIED_00057 3.1e-57 crgA D Involved in cell division
EPNMAIED_00058 6.8e-142 S Bacterial protein of unknown function (DUF881)
EPNMAIED_00059 6.7e-209 srtA 3.4.22.70 M Sortase family
EPNMAIED_00060 1.3e-116 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
EPNMAIED_00061 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
EPNMAIED_00062 5.8e-177 T Protein tyrosine kinase
EPNMAIED_00063 8.8e-265 pbpA M penicillin-binding protein
EPNMAIED_00064 1.7e-261 rodA D Belongs to the SEDS family
EPNMAIED_00065 6.7e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
EPNMAIED_00066 5.2e-71 fhaB T Inner membrane component of T3SS, cytoplasmic domain
EPNMAIED_00067 1.2e-131 fhaA T Protein of unknown function (DUF2662)
EPNMAIED_00068 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
EPNMAIED_00069 6.2e-222 2.7.13.3 T Histidine kinase
EPNMAIED_00070 3.2e-113 K helix_turn_helix, Lux Regulon
EPNMAIED_00071 7.8e-194 pldB 3.1.1.5 I Serine aminopeptidase, S33
EPNMAIED_00072 8.8e-160 yicL EG EamA-like transporter family
EPNMAIED_00079 1.2e-36 K helix_turn_helix, Lux Regulon
EPNMAIED_00080 4.7e-268 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
EPNMAIED_00081 2.7e-285 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
EPNMAIED_00082 0.0 cadA P E1-E2 ATPase
EPNMAIED_00083 9.3e-189 ansA 3.5.1.1 EJ Asparaginase
EPNMAIED_00084 6.9e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
EPNMAIED_00085 4.7e-162 htpX O Belongs to the peptidase M48B family
EPNMAIED_00087 9.4e-65 K Helix-turn-helix XRE-family like proteins
EPNMAIED_00088 1.6e-169 yddG EG EamA-like transporter family
EPNMAIED_00089 0.0 pip S YhgE Pip domain protein
EPNMAIED_00090 0.0 pip S YhgE Pip domain protein
EPNMAIED_00091 1.6e-205 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
EPNMAIED_00092 7.8e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EPNMAIED_00093 1e-295 clcA P Voltage gated chloride channel
EPNMAIED_00094 3.9e-129 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPNMAIED_00095 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPNMAIED_00096 1.4e-29 E Receptor family ligand binding region
EPNMAIED_00097 1.8e-198 K helix_turn _helix lactose operon repressor
EPNMAIED_00098 1e-295 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
EPNMAIED_00099 1.5e-115 S Protein of unknown function, DUF624
EPNMAIED_00100 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
EPNMAIED_00101 1.4e-218 G Bacterial extracellular solute-binding protein
EPNMAIED_00102 2.9e-162 amyD3 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00103 1.6e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00104 1.7e-277 scrT G Transporter major facilitator family protein
EPNMAIED_00105 1.5e-242 yhjE EGP Sugar (and other) transporter
EPNMAIED_00106 1.3e-201 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EPNMAIED_00107 5.8e-202 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EPNMAIED_00108 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
EPNMAIED_00109 2.3e-154 E GDSL-like Lipase/Acylhydrolase family
EPNMAIED_00110 7.7e-255 bglA 3.2.1.21 G Glycosyl hydrolase family 1
EPNMAIED_00111 8.1e-220 G Bacterial extracellular solute-binding protein
EPNMAIED_00112 2e-170 ycjO_3 U Binding-protein-dependent transport system inner membrane component
EPNMAIED_00113 5.7e-76 malG U Binding-protein-dependent transport system inner membrane component
EPNMAIED_00114 1.7e-51 malG U Binding-protein-dependent transport system inner membrane component
EPNMAIED_00115 0.0 3.2.1.25 G beta-mannosidase
EPNMAIED_00116 6e-183 K helix_turn _helix lactose operon repressor
EPNMAIED_00117 3.2e-83 S Protein of unknown function, DUF624
EPNMAIED_00118 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
EPNMAIED_00119 1.2e-100
EPNMAIED_00120 4.4e-270 aroP E aromatic amino acid transport protein AroP K03293
EPNMAIED_00121 0.0 V FtsX-like permease family
EPNMAIED_00122 2.7e-229 P Sodium/hydrogen exchanger family
EPNMAIED_00123 1.3e-76 S Psort location Cytoplasmic, score 8.87
EPNMAIED_00124 8.4e-183 3.4.22.70 M Sortase family
EPNMAIED_00125 1.6e-121 Q von Willebrand factor (vWF) type A domain
EPNMAIED_00126 1.4e-201 M LPXTG cell wall anchor motif
EPNMAIED_00127 2.5e-89 S Psort location Cytoplasmic, score 8.87
EPNMAIED_00128 3.2e-273 cycA E Amino acid permease
EPNMAIED_00129 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
EPNMAIED_00130 6.5e-128 thiF 2.7.7.73, 2.7.7.80 H ThiF family
EPNMAIED_00131 3.8e-26 thiS 2.8.1.10 H ThiS family
EPNMAIED_00132 1.4e-192 1.1.1.65 C Aldo/keto reductase family
EPNMAIED_00133 1.9e-57 ydgJ K helix_turn_helix multiple antibiotic resistance protein
EPNMAIED_00134 2.7e-285 lmrA1 V ABC transporter, ATP-binding protein
EPNMAIED_00135 0.0 lmrA2 V ABC transporter transmembrane region
EPNMAIED_00136 1.1e-117 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
EPNMAIED_00137 9.8e-237 G MFS/sugar transport protein
EPNMAIED_00138 3.7e-294 efeU_1 P Iron permease FTR1 family
EPNMAIED_00139 1.4e-92 tpd P Fe2+ transport protein
EPNMAIED_00140 3.2e-231 S Predicted membrane protein (DUF2318)
EPNMAIED_00141 1.8e-219 macB_2 V ABC transporter permease
EPNMAIED_00143 4.5e-201 Z012_06715 V FtsX-like permease family
EPNMAIED_00144 2.2e-148 macB V ABC transporter, ATP-binding protein
EPNMAIED_00145 1.1e-61 S FMN_bind
EPNMAIED_00146 1.2e-88 K Psort location Cytoplasmic, score 8.87
EPNMAIED_00147 1.1e-274 pip S YhgE Pip domain protein
EPNMAIED_00148 0.0 pip S YhgE Pip domain protein
EPNMAIED_00149 4.1e-226 S Putative ABC-transporter type IV
EPNMAIED_00150 6e-38 nrdH O Glutaredoxin
EPNMAIED_00152 1.3e-304 pepD E Peptidase family C69
EPNMAIED_00153 4e-195 XK27_01805 M Glycosyltransferase like family 2
EPNMAIED_00154 1.1e-107 icaR K Bacterial regulatory proteins, tetR family
EPNMAIED_00156 7.3e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
EPNMAIED_00157 1.5e-236 amt U Ammonium Transporter Family
EPNMAIED_00158 1e-54 glnB K Nitrogen regulatory protein P-II
EPNMAIED_00159 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
EPNMAIED_00160 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
EPNMAIED_00161 2.3e-252 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
EPNMAIED_00162 6.2e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
EPNMAIED_00163 1e-27 S granule-associated protein
EPNMAIED_00164 0.0 ubiB S ABC1 family
EPNMAIED_00165 2e-191 K Periplasmic binding protein domain
EPNMAIED_00166 1.1e-242 G Bacterial extracellular solute-binding protein
EPNMAIED_00167 1.5e-07 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00168 3.1e-167 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00169 9.3e-147 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_00170 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
EPNMAIED_00171 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
EPNMAIED_00172 0.0 G Bacterial Ig-like domain (group 4)
EPNMAIED_00173 3.2e-208 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
EPNMAIED_00174 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EPNMAIED_00175 5e-91
EPNMAIED_00176 2.3e-223 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
EPNMAIED_00177 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EPNMAIED_00178 1.1e-141 cpaE D bacterial-type flagellum organization
EPNMAIED_00179 1.8e-184 cpaF U Type II IV secretion system protein
EPNMAIED_00180 1.1e-125 U Type ii secretion system
EPNMAIED_00181 2.2e-88 gspF NU Type II secretion system (T2SS), protein F
EPNMAIED_00182 1.3e-42 S Protein of unknown function (DUF4244)
EPNMAIED_00183 5.1e-60 U TadE-like protein
EPNMAIED_00184 3e-55 S TIGRFAM helicase secretion neighborhood TadE-like protein
EPNMAIED_00185 1.9e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
EPNMAIED_00186 1.6e-193 S Psort location CytoplasmicMembrane, score
EPNMAIED_00187 1.1e-96 K Bacterial regulatory proteins, tetR family
EPNMAIED_00188 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
EPNMAIED_00189 4.5e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EPNMAIED_00190 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
EPNMAIED_00191 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
EPNMAIED_00192 1.8e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EPNMAIED_00193 2.7e-48 yitI S Acetyltransferase (GNAT) domain
EPNMAIED_00194 2.4e-115
EPNMAIED_00195 1.5e-302 S Calcineurin-like phosphoesterase
EPNMAIED_00196 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EPNMAIED_00197 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
EPNMAIED_00198 2.1e-256 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
EPNMAIED_00199 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
EPNMAIED_00200 1.1e-195 K helix_turn _helix lactose operon repressor
EPNMAIED_00201 1.3e-203 abf G Glycosyl hydrolases family 43
EPNMAIED_00202 1.1e-292 G Bacterial extracellular solute-binding protein
EPNMAIED_00203 4.6e-169 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_00204 1.7e-163 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_00205 1.2e-183 G beta-fructofuranosidase activity
EPNMAIED_00206 8.5e-101 S Protein of unknown function, DUF624
EPNMAIED_00207 1.1e-25 S Beta-L-arabinofuranosidase, GH127
EPNMAIED_00208 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
EPNMAIED_00209 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
EPNMAIED_00210 1.3e-234 glf 5.4.99.9 M UDP-galactopyranose mutase
EPNMAIED_00211 6.9e-188 3.6.1.27 I PAP2 superfamily
EPNMAIED_00212 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EPNMAIED_00213 3.2e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EPNMAIED_00214 9.3e-193 holB 2.7.7.7 L DNA polymerase III
EPNMAIED_00215 1.1e-184 K helix_turn _helix lactose operon repressor
EPNMAIED_00216 6e-39 ptsH G PTS HPr component phosphorylation site
EPNMAIED_00217 1.4e-298 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EPNMAIED_00218 4.9e-107 S Phosphatidylethanolamine-binding protein
EPNMAIED_00219 0.0 pepD E Peptidase family C69
EPNMAIED_00220 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
EPNMAIED_00221 6.7e-62 S Macrophage migration inhibitory factor (MIF)
EPNMAIED_00222 6.4e-96 S GtrA-like protein
EPNMAIED_00223 2.1e-263 EGP Major facilitator Superfamily
EPNMAIED_00224 4.1e-121 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
EPNMAIED_00225 7e-184
EPNMAIED_00226 4.1e-99 S Protein of unknown function (DUF805)
EPNMAIED_00227 1.2e-296 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EPNMAIED_00230 1.6e-269 S Calcineurin-like phosphoesterase
EPNMAIED_00231 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
EPNMAIED_00232 3.6e-271 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPNMAIED_00233 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EPNMAIED_00234 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
EPNMAIED_00235 2.3e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EPNMAIED_00236 2.7e-176 plsC2 2.3.1.51 I Phosphate acyltransferases
EPNMAIED_00237 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
EPNMAIED_00238 5.2e-220 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
EPNMAIED_00239 2.4e-174 S CAAX protease self-immunity
EPNMAIED_00240 1.7e-137 M Mechanosensitive ion channel
EPNMAIED_00241 5e-229 MA20_36090 S Psort location Cytoplasmic, score 8.87
EPNMAIED_00242 2.4e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
EPNMAIED_00243 3.7e-125 K Bacterial regulatory proteins, tetR family
EPNMAIED_00244 8.8e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
EPNMAIED_00245 5.2e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
EPNMAIED_00247 6e-228 gnuT EG GntP family permease
EPNMAIED_00248 2.1e-83 gntK 2.7.1.12 F Shikimate kinase
EPNMAIED_00249 1.6e-126 gntR K FCD
EPNMAIED_00250 1.1e-229 yxiO S Vacuole effluxer Atg22 like
EPNMAIED_00251 0.0 S Psort location Cytoplasmic, score 8.87
EPNMAIED_00252 8.4e-30 rpmB J Ribosomal L28 family
EPNMAIED_00253 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
EPNMAIED_00254 1.9e-104 rsmD 2.1.1.171 L Conserved hypothetical protein 95
EPNMAIED_00255 1.5e-149 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
EPNMAIED_00256 6.8e-107 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EPNMAIED_00257 1.8e-34 CP_0960 S Belongs to the UPF0109 family
EPNMAIED_00258 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
EPNMAIED_00259 2e-178 S Endonuclease/Exonuclease/phosphatase family
EPNMAIED_00260 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EPNMAIED_00261 2.1e-302 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
EPNMAIED_00262 1.9e-152 guaA1 6.3.5.2 F Peptidase C26
EPNMAIED_00263 0.0 yjjK S ABC transporter
EPNMAIED_00264 1.1e-95
EPNMAIED_00265 5.7e-92 ilvN 2.2.1.6 E ACT domain
EPNMAIED_00266 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
EPNMAIED_00267 3.7e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
EPNMAIED_00268 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
EPNMAIED_00269 8.8e-113 yceD S Uncharacterized ACR, COG1399
EPNMAIED_00270 8.5e-134
EPNMAIED_00271 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EPNMAIED_00272 6.1e-57 S Protein of unknown function (DUF3039)
EPNMAIED_00273 1.7e-195 yghZ C Aldo/keto reductase family
EPNMAIED_00274 3.2e-77 soxR K MerR, DNA binding
EPNMAIED_00275 3.6e-120 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EPNMAIED_00276 1e-139 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EPNMAIED_00277 2.1e-249 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EPNMAIED_00278 4.9e-219 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
EPNMAIED_00279 1.5e-220 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
EPNMAIED_00282 5.4e-181 S Auxin Efflux Carrier
EPNMAIED_00283 0.0 pgi 5.3.1.9 G Belongs to the GPI family
EPNMAIED_00284 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
EPNMAIED_00285 1.1e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
EPNMAIED_00286 2.1e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPNMAIED_00287 5e-128 V ATPases associated with a variety of cellular activities
EPNMAIED_00288 2.5e-270 V Efflux ABC transporter, permease protein
EPNMAIED_00289 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
EPNMAIED_00290 4e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
EPNMAIED_00291 1.5e-308 rne 3.1.26.12 J Ribonuclease E/G family
EPNMAIED_00292 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
EPNMAIED_00293 2.6e-39 rpmA J Ribosomal L27 protein
EPNMAIED_00294 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EPNMAIED_00295 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EPNMAIED_00296 3.3e-233 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
EPNMAIED_00298 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
EPNMAIED_00299 1.1e-128 nusG K Participates in transcription elongation, termination and antitermination
EPNMAIED_00300 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EPNMAIED_00301 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
EPNMAIED_00302 5.9e-143 QT PucR C-terminal helix-turn-helix domain
EPNMAIED_00303 0.0
EPNMAIED_00304 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
EPNMAIED_00305 9.6e-77 bioY S BioY family
EPNMAIED_00306 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
EPNMAIED_00307 0.0 pccB I Carboxyl transferase domain
EPNMAIED_00308 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
EPNMAIED_00310 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
EPNMAIED_00311 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
EPNMAIED_00313 2.4e-116
EPNMAIED_00314 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EPNMAIED_00315 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
EPNMAIED_00316 8.5e-91 lemA S LemA family
EPNMAIED_00317 0.0 S Predicted membrane protein (DUF2207)
EPNMAIED_00318 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
EPNMAIED_00319 7e-297 yegQ O Peptidase family U32 C-terminal domain
EPNMAIED_00320 4.1e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
EPNMAIED_00321 2.5e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
EPNMAIED_00322 1e-125 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EPNMAIED_00323 5e-50 D nuclear chromosome segregation
EPNMAIED_00324 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
EPNMAIED_00325 3.7e-210 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPNMAIED_00326 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EPNMAIED_00327 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EPNMAIED_00328 1.1e-219 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
EPNMAIED_00329 3.4e-129 KT Transcriptional regulatory protein, C terminal
EPNMAIED_00330 1.6e-197 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
EPNMAIED_00331 3.4e-164 pstC P probably responsible for the translocation of the substrate across the membrane
EPNMAIED_00332 4e-168 pstA P Phosphate transport system permease
EPNMAIED_00333 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
EPNMAIED_00334 5.2e-143 P Zinc-uptake complex component A periplasmic
EPNMAIED_00335 1.3e-246 pbuO S Permease family
EPNMAIED_00336 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EPNMAIED_00337 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
EPNMAIED_00338 3.6e-175 T Forkhead associated domain
EPNMAIED_00339 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
EPNMAIED_00340 4.8e-36
EPNMAIED_00341 6.5e-93 flgA NO SAF
EPNMAIED_00342 1.3e-29 fmdB S Putative regulatory protein
EPNMAIED_00343 1.6e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
EPNMAIED_00344 6.7e-113 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
EPNMAIED_00345 1.7e-152
EPNMAIED_00346 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EPNMAIED_00350 5.5e-25 rpmG J Ribosomal protein L33
EPNMAIED_00351 9.3e-204 murB 1.3.1.98 M Cell wall formation
EPNMAIED_00352 1.3e-266 E aromatic amino acid transport protein AroP K03293
EPNMAIED_00353 8.3e-59 fdxA C 4Fe-4S binding domain
EPNMAIED_00354 5.2e-212 dapC E Aminotransferase class I and II
EPNMAIED_00355 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
EPNMAIED_00356 3.1e-181 EP Binding-protein-dependent transport system inner membrane component
EPNMAIED_00357 1.1e-140 EP Binding-protein-dependent transport system inner membrane component
EPNMAIED_00358 5.1e-156 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
EPNMAIED_00359 2.8e-151 dppF E ABC transporter
EPNMAIED_00360 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EPNMAIED_00361 0.0 G Psort location Cytoplasmic, score 8.87
EPNMAIED_00362 1e-231 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
EPNMAIED_00363 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
EPNMAIED_00364 9.6e-296 CE10 I Belongs to the type-B carboxylesterase lipase family
EPNMAIED_00366 7.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EPNMAIED_00367 1e-251 M Bacterial capsule synthesis protein PGA_cap
EPNMAIED_00368 9.4e-186 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EPNMAIED_00369 2.1e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
EPNMAIED_00370 6.9e-122
EPNMAIED_00371 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
EPNMAIED_00372 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EPNMAIED_00373 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
EPNMAIED_00374 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EPNMAIED_00375 1.4e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
EPNMAIED_00376 1e-215 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
EPNMAIED_00377 7.2e-239 EGP Major facilitator Superfamily
EPNMAIED_00378 3.3e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
EPNMAIED_00379 1.1e-181 rhaR_1 K helix_turn_helix, arabinose operon control protein
EPNMAIED_00380 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
EPNMAIED_00381 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
EPNMAIED_00382 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EPNMAIED_00383 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
EPNMAIED_00384 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
EPNMAIED_00385 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EPNMAIED_00386 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EPNMAIED_00387 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EPNMAIED_00388 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EPNMAIED_00389 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EPNMAIED_00390 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
EPNMAIED_00391 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EPNMAIED_00392 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EPNMAIED_00393 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EPNMAIED_00394 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EPNMAIED_00395 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EPNMAIED_00396 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EPNMAIED_00397 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EPNMAIED_00398 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EPNMAIED_00399 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EPNMAIED_00400 3.4e-25 rpmD J Ribosomal protein L30p/L7e
EPNMAIED_00401 9.8e-74 rplO J binds to the 23S rRNA
EPNMAIED_00402 9.9e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
EPNMAIED_00403 2.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
EPNMAIED_00404 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EPNMAIED_00405 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
EPNMAIED_00406 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EPNMAIED_00407 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EPNMAIED_00408 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPNMAIED_00409 1.3e-66 rplQ J Ribosomal protein L17
EPNMAIED_00410 9.8e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
EPNMAIED_00412 2.8e-77
EPNMAIED_00413 6.1e-191 nusA K Participates in both transcription termination and antitermination
EPNMAIED_00414 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EPNMAIED_00415 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EPNMAIED_00416 3.9e-188 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EPNMAIED_00417 3e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
EPNMAIED_00418 4.1e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EPNMAIED_00419 1.9e-107
EPNMAIED_00421 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EPNMAIED_00422 1.1e-212 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EPNMAIED_00423 3e-251 T GHKL domain
EPNMAIED_00424 2.1e-151 T LytTr DNA-binding domain
EPNMAIED_00425 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
EPNMAIED_00426 0.0 crr G pts system, glucose-specific IIABC component
EPNMAIED_00427 2.8e-157 arbG K CAT RNA binding domain
EPNMAIED_00428 8.3e-199 I Diacylglycerol kinase catalytic domain
EPNMAIED_00429 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EPNMAIED_00431 4.6e-188 yegU O ADP-ribosylglycohydrolase
EPNMAIED_00432 1.9e-189 yegV G pfkB family carbohydrate kinase
EPNMAIED_00433 1.1e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
EPNMAIED_00434 4.3e-103 Q Isochorismatase family
EPNMAIED_00435 2.3e-214 S Choline/ethanolamine kinase
EPNMAIED_00436 2.5e-275 eat E Amino acid permease
EPNMAIED_00437 2e-263 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
EPNMAIED_00438 3.9e-142 yidP K UTRA
EPNMAIED_00439 5.6e-121 degU K helix_turn_helix, Lux Regulon
EPNMAIED_00440 5.7e-273 tcsS3 KT PspC domain
EPNMAIED_00441 6.6e-60 pspC KT PspC domain
EPNMAIED_00442 4.4e-162 pspC KT PspC domain
EPNMAIED_00443 1.6e-92
EPNMAIED_00444 8.8e-116 S Protein of unknown function (DUF4125)
EPNMAIED_00445 0.0 S Domain of unknown function (DUF4037)
EPNMAIED_00446 9.2e-212 araJ EGP Major facilitator Superfamily
EPNMAIED_00448 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
EPNMAIED_00449 3.9e-190 K helix_turn _helix lactose operon repressor
EPNMAIED_00450 2.2e-249 G Psort location CytoplasmicMembrane, score 10.00
EPNMAIED_00451 1.2e-98 S Serine aminopeptidase, S33
EPNMAIED_00452 1.1e-206 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
EPNMAIED_00453 2.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EPNMAIED_00454 0.0 4.2.1.53 S MCRA family
EPNMAIED_00455 7.4e-89 phoU P Plays a role in the regulation of phosphate uptake
EPNMAIED_00456 9e-215 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EPNMAIED_00457 6.2e-41
EPNMAIED_00458 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EPNMAIED_00459 1.1e-164 usp 3.5.1.28 CBM50 S CHAP domain
EPNMAIED_00460 1.3e-79 M NlpC/P60 family
EPNMAIED_00461 2.3e-190 T Universal stress protein family
EPNMAIED_00462 1e-72 attW O OsmC-like protein
EPNMAIED_00463 8.4e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EPNMAIED_00464 6.4e-130 folA 1.5.1.3 H dihydrofolate reductase
EPNMAIED_00465 6.8e-84 ptpA 3.1.3.48 T low molecular weight
EPNMAIED_00467 9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
EPNMAIED_00468 7.7e-171 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
EPNMAIED_00472 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
EPNMAIED_00473 2.2e-160
EPNMAIED_00474 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
EPNMAIED_00475 3.5e-282 pelF GT4 M Domain of unknown function (DUF3492)
EPNMAIED_00476 2.1e-285 pelG S Putative exopolysaccharide Exporter (EPS-E)
EPNMAIED_00477 8.8e-307 cotH M CotH kinase protein
EPNMAIED_00478 1.4e-158 P VTC domain
EPNMAIED_00479 8.5e-111 S Domain of unknown function (DUF4956)
EPNMAIED_00480 0.0 yliE T Putative diguanylate phosphodiesterase
EPNMAIED_00481 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
EPNMAIED_00482 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
EPNMAIED_00483 1.3e-237 S AI-2E family transporter
EPNMAIED_00484 6.3e-232 epsG M Glycosyl transferase family 21
EPNMAIED_00485 5.7e-232 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
EPNMAIED_00486 1.5e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
EPNMAIED_00487 3.9e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
EPNMAIED_00488 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EPNMAIED_00489 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
EPNMAIED_00490 6.9e-156 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EPNMAIED_00491 1.4e-273 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EPNMAIED_00492 6.2e-94 S Protein of unknown function (DUF3180)
EPNMAIED_00493 8.5e-165 tesB I Thioesterase-like superfamily
EPNMAIED_00494 0.0 yjjK S ATP-binding cassette protein, ChvD family
EPNMAIED_00495 2.2e-181 V Beta-lactamase
EPNMAIED_00496 2.5e-74 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
EPNMAIED_00497 1.5e-81 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
EPNMAIED_00498 1.8e-155 L PFAM Integrase catalytic
EPNMAIED_00499 5.5e-12 L PFAM Integrase catalytic
EPNMAIED_00500 0.0 O Highly conserved protein containing a thioredoxin domain
EPNMAIED_00501 4.6e-229 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
EPNMAIED_00502 0.0 3.2.1.8 G Glycosyl hydrolase family 10
EPNMAIED_00503 2.9e-118 L Integrase core domain
EPNMAIED_00505 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
EPNMAIED_00506 1.2e-224 bdhA C Iron-containing alcohol dehydrogenase
EPNMAIED_00507 1.1e-24 ykoE S ABC-type cobalt transport system, permease component
EPNMAIED_00508 1.7e-16 ydcZ S Putative inner membrane exporter, YdcZ
EPNMAIED_00509 8.3e-35 S Membrane
EPNMAIED_00511 3.1e-51 S Membrane
EPNMAIED_00512 9.2e-270 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
EPNMAIED_00513 9.2e-250 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
EPNMAIED_00514 8.7e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
EPNMAIED_00515 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
EPNMAIED_00516 2.5e-181 K Bacterial regulatory proteins, lacI family
EPNMAIED_00517 9.4e-239 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
EPNMAIED_00518 1.7e-185 MA20_14025 U Binding-protein-dependent transport system inner membrane component
EPNMAIED_00519 2.4e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00520 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
EPNMAIED_00521 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
EPNMAIED_00522 4.8e-08 CE10 I Belongs to the type-B carboxylesterase lipase family
EPNMAIED_00523 4.7e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
EPNMAIED_00524 6.5e-287 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
EPNMAIED_00525 5e-221 xylR GK ROK family
EPNMAIED_00527 1.5e-35 rpmE J Binds the 23S rRNA
EPNMAIED_00528 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EPNMAIED_00529 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
EPNMAIED_00530 1.7e-218 livK E Receptor family ligand binding region
EPNMAIED_00531 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
EPNMAIED_00532 1.4e-196 livM U Belongs to the binding-protein-dependent transport system permease family
EPNMAIED_00533 4.8e-151 E Branched-chain amino acid ATP-binding cassette transporter
EPNMAIED_00534 1.9e-124 livF E ATPases associated with a variety of cellular activities
EPNMAIED_00535 3.8e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
EPNMAIED_00536 4.9e-194 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
EPNMAIED_00537 2.2e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
EPNMAIED_00538 8.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
EPNMAIED_00539 4.5e-163 supH S Sucrose-6F-phosphate phosphohydrolase
EPNMAIED_00540 1.9e-269 recD2 3.6.4.12 L PIF1-like helicase
EPNMAIED_00541 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
EPNMAIED_00542 2e-97 L Single-strand binding protein family
EPNMAIED_00543 0.0 pepO 3.4.24.71 O Peptidase family M13
EPNMAIED_00544 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
EPNMAIED_00545 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
EPNMAIED_00546 2.9e-142 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
EPNMAIED_00547 1.2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EPNMAIED_00548 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
EPNMAIED_00549 2.3e-168 ftsE D Cell division ATP-binding protein FtsE
EPNMAIED_00550 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
EPNMAIED_00551 8.5e-148 usp 3.5.1.28 CBM50 D CHAP domain protein
EPNMAIED_00552 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
EPNMAIED_00553 5.7e-156 pknD ET ABC transporter, substrate-binding protein, family 3
EPNMAIED_00554 8.9e-32 pknD ET ABC transporter, substrate-binding protein, family 3
EPNMAIED_00555 1.6e-150 pknD ET ABC transporter, substrate-binding protein, family 3
EPNMAIED_00556 2.2e-126 yecS E Binding-protein-dependent transport system inner membrane component
EPNMAIED_00557 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
EPNMAIED_00558 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
EPNMAIED_00559 2.1e-145 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
EPNMAIED_00560 9e-229 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EPNMAIED_00561 1.4e-189 K Periplasmic binding protein domain
EPNMAIED_00562 1.1e-164 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_00563 2.6e-167 G ABC transporter permease
EPNMAIED_00564 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EPNMAIED_00565 2.2e-311 abfA1 3.2.1.55 GH51 G arabinose metabolic process
EPNMAIED_00566 1.6e-191 G Bacterial extracellular solute-binding protein
EPNMAIED_00567 2e-42 G Bacterial extracellular solute-binding protein
EPNMAIED_00568 1.2e-274 G Bacterial extracellular solute-binding protein
EPNMAIED_00569 5.9e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EPNMAIED_00570 7e-242 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EPNMAIED_00571 3.9e-293 E ABC transporter, substrate-binding protein, family 5
EPNMAIED_00572 1.3e-166 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00573 1.2e-139 EP Binding-protein-dependent transport system inner membrane component
EPNMAIED_00574 7.1e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
EPNMAIED_00575 1e-139 sapF E ATPases associated with a variety of cellular activities
EPNMAIED_00576 9.9e-191 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
EPNMAIED_00577 7e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EPNMAIED_00578 0.0 macB_2 V ATPases associated with a variety of cellular activities
EPNMAIED_00579 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
EPNMAIED_00580 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
EPNMAIED_00581 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EPNMAIED_00582 4e-270 yhdG E aromatic amino acid transport protein AroP K03293
EPNMAIED_00583 1.3e-306 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EPNMAIED_00584 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
EPNMAIED_00585 4e-215 ybiR P Citrate transporter
EPNMAIED_00587 0.0 tetP J Elongation factor G, domain IV
EPNMAIED_00591 2e-101 K acetyltransferase
EPNMAIED_00592 4.7e-109 papP E Binding-protein-dependent transport system inner membrane component
EPNMAIED_00593 3.6e-120 E Binding-protein-dependent transport system inner membrane component
EPNMAIED_00594 1.5e-152 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
EPNMAIED_00595 6.9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
EPNMAIED_00596 1.4e-200 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EPNMAIED_00597 4.3e-158 metQ M NLPA lipoprotein
EPNMAIED_00598 6.5e-193 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPNMAIED_00599 4.9e-98 metI P Psort location CytoplasmicMembrane, score 9.99
EPNMAIED_00600 4.8e-221 mtnE 2.6.1.83 E Aminotransferase class I and II
EPNMAIED_00601 3.2e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EPNMAIED_00602 1.4e-43 XAC3035 O Glutaredoxin
EPNMAIED_00603 3.1e-127 XK27_08050 O prohibitin homologues
EPNMAIED_00604 6.9e-15 S Domain of unknown function (DUF4143)
EPNMAIED_00605 7.4e-75
EPNMAIED_00606 9.6e-135 V ATPases associated with a variety of cellular activities
EPNMAIED_00607 1.1e-145 M Conserved repeat domain
EPNMAIED_00608 7.5e-256 macB_8 V MacB-like periplasmic core domain
EPNMAIED_00609 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EPNMAIED_00610 1.3e-182 adh3 C Zinc-binding dehydrogenase
EPNMAIED_00611 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EPNMAIED_00612 6.4e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EPNMAIED_00613 6.8e-89 zur P Belongs to the Fur family
EPNMAIED_00614 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
EPNMAIED_00615 4.2e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
EPNMAIED_00616 9.1e-189 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
EPNMAIED_00617 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
EPNMAIED_00618 1.1e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
EPNMAIED_00619 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EPNMAIED_00620 2.1e-247 EGP Major facilitator Superfamily
EPNMAIED_00621 6.3e-235 purD 6.3.4.13 F Belongs to the GARS family
EPNMAIED_00622 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
EPNMAIED_00623 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EPNMAIED_00624 2.3e-311 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
EPNMAIED_00625 1.9e-36
EPNMAIED_00626 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
EPNMAIED_00627 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
EPNMAIED_00628 4.3e-228 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EPNMAIED_00629 6.5e-226 M Glycosyl transferase 4-like domain
EPNMAIED_00630 2.9e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
EPNMAIED_00632 8.4e-105 yocS S SBF-like CPA transporter family (DUF4137)
EPNMAIED_00633 4.8e-73 yocS S SBF-like CPA transporter family (DUF4137)
EPNMAIED_00634 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EPNMAIED_00635 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
EPNMAIED_00636 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EPNMAIED_00637 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EPNMAIED_00638 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EPNMAIED_00639 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EPNMAIED_00640 4.1e-239 carA 6.3.5.5 F Belongs to the CarA family
EPNMAIED_00641 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
EPNMAIED_00642 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
EPNMAIED_00643 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
EPNMAIED_00645 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
EPNMAIED_00646 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
EPNMAIED_00647 4.2e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EPNMAIED_00648 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EPNMAIED_00649 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EPNMAIED_00650 2.4e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EPNMAIED_00651 1.6e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
EPNMAIED_00652 2.2e-282 arc O AAA ATPase forming ring-shaped complexes
EPNMAIED_00653 1.2e-302 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
EPNMAIED_00654 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
EPNMAIED_00655 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
EPNMAIED_00656 6.7e-281 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
EPNMAIED_00657 9.7e-141 C FMN binding
EPNMAIED_00658 1.8e-57
EPNMAIED_00659 1.4e-41 hup L Belongs to the bacterial histone-like protein family
EPNMAIED_00660 0.0 S Lysylphosphatidylglycerol synthase TM region
EPNMAIED_00661 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
EPNMAIED_00662 3.5e-277 S PGAP1-like protein
EPNMAIED_00663 3.2e-61
EPNMAIED_00664 1.9e-181 S von Willebrand factor (vWF) type A domain
EPNMAIED_00665 1.6e-191 S von Willebrand factor (vWF) type A domain
EPNMAIED_00666 3.6e-91
EPNMAIED_00667 1.6e-174 S Protein of unknown function DUF58
EPNMAIED_00668 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
EPNMAIED_00669 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EPNMAIED_00670 8.5e-77 S LytR cell envelope-related transcriptional attenuator
EPNMAIED_00671 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
EPNMAIED_00673 1.3e-124
EPNMAIED_00674 2.6e-132 KT Response regulator receiver domain protein
EPNMAIED_00675 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EPNMAIED_00676 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
EPNMAIED_00677 1.2e-182 S Protein of unknown function (DUF3027)
EPNMAIED_00678 4.6e-188 uspA T Belongs to the universal stress protein A family
EPNMAIED_00679 0.0 clpC O ATPase family associated with various cellular activities (AAA)
EPNMAIED_00680 1.3e-254 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
EPNMAIED_00681 4.7e-285 purR QT Purine catabolism regulatory protein-like family
EPNMAIED_00682 1.1e-245 proP EGP Sugar (and other) transporter
EPNMAIED_00683 4.6e-140 3.5.2.10 S Creatinine amidohydrolase
EPNMAIED_00684 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
EPNMAIED_00685 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
EPNMAIED_00686 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EPNMAIED_00687 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
EPNMAIED_00688 6.7e-139 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
EPNMAIED_00689 6.2e-137 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
EPNMAIED_00690 4e-153 gluB ET Belongs to the bacterial solute-binding protein 3 family
EPNMAIED_00691 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
EPNMAIED_00692 5e-199 gluD E Binding-protein-dependent transport system inner membrane component
EPNMAIED_00693 1.3e-190 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
EPNMAIED_00694 0.0 L DEAD DEAH box helicase
EPNMAIED_00695 3.1e-251 rarA L Recombination factor protein RarA
EPNMAIED_00696 4.9e-258 EGP Major facilitator Superfamily
EPNMAIED_00697 0.0 E ABC transporter, substrate-binding protein, family 5
EPNMAIED_00698 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPNMAIED_00699 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
EPNMAIED_00700 6.1e-241 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EPNMAIED_00703 3.9e-246 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EPNMAIED_00704 4.8e-117 safC S O-methyltransferase
EPNMAIED_00705 7.5e-177 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
EPNMAIED_00706 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
EPNMAIED_00707 1e-254 dprA 5.99.1.2 LU DNA recombination-mediator protein A
EPNMAIED_00708 1e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
EPNMAIED_00709 3.1e-83 yraN L Belongs to the UPF0102 family
EPNMAIED_00710 5.6e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
EPNMAIED_00711 5.9e-252 metY 2.5.1.49 E Aminotransferase class-V
EPNMAIED_00712 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
EPNMAIED_00713 4.6e-307 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
EPNMAIED_00714 5.8e-149 P Cobalt transport protein
EPNMAIED_00715 8.2e-193 K helix_turn_helix ASNC type
EPNMAIED_00716 5.1e-142 V ABC transporter, ATP-binding protein
EPNMAIED_00717 0.0 MV MacB-like periplasmic core domain
EPNMAIED_00718 1.2e-129 K helix_turn_helix, Lux Regulon
EPNMAIED_00719 0.0 tcsS2 T Histidine kinase
EPNMAIED_00720 1.7e-267 pip 3.4.11.5 S alpha/beta hydrolase fold
EPNMAIED_00721 1.4e-142 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EPNMAIED_00722 3.9e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
EPNMAIED_00723 5.9e-12
EPNMAIED_00724 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
EPNMAIED_00725 1.8e-29
EPNMAIED_00726 1e-94
EPNMAIED_00727 1.1e-165 MA20_14895 S Conserved hypothetical protein 698
EPNMAIED_00728 5.6e-186 C Na H antiporter family protein
EPNMAIED_00729 6.1e-163 korD 1.2.7.3 C Domain of unknown function (DUF362)
EPNMAIED_00730 1.4e-112 2.7.1.48 F uridine kinase
EPNMAIED_00731 1.9e-93 S ECF transporter, substrate-specific component
EPNMAIED_00732 1.4e-137 S Sulfite exporter TauE/SafE
EPNMAIED_00733 7e-141 K helix_turn_helix, arabinose operon control protein
EPNMAIED_00734 1.4e-155 3.1.3.73 G Phosphoglycerate mutase family
EPNMAIED_00735 2.9e-227 rutG F Permease family
EPNMAIED_00736 1.6e-126 S Enoyl-(Acyl carrier protein) reductase
EPNMAIED_00737 6e-275 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
EPNMAIED_00738 1.8e-134 ybbM V Uncharacterised protein family (UPF0014)
EPNMAIED_00739 9.2e-142 ybbL V ATPases associated with a variety of cellular activities
EPNMAIED_00740 5.9e-242 S Putative esterase
EPNMAIED_00741 0.0 lysX S Uncharacterised conserved protein (DUF2156)
EPNMAIED_00742 1.2e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EPNMAIED_00743 5.3e-147 S Belongs to the short-chain dehydrogenases reductases (SDR) family
EPNMAIED_00744 8.2e-237 patB 4.4.1.8 E Aminotransferase, class I II
EPNMAIED_00745 3.6e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EPNMAIED_00746 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
EPNMAIED_00747 3.4e-146 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
EPNMAIED_00748 1.6e-82 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPNMAIED_00749 1.3e-79 M Protein of unknown function (DUF3737)
EPNMAIED_00750 7.9e-143 azlC E AzlC protein
EPNMAIED_00751 5.5e-53 azlD E Branched-chain amino acid transport protein (AzlD)
EPNMAIED_00752 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
EPNMAIED_00753 6.2e-40 ybdD S Selenoprotein, putative
EPNMAIED_00754 1e-176 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
EPNMAIED_00755 0.0 S Uncharacterised protein family (UPF0182)
EPNMAIED_00756 1.2e-99 2.3.1.183 M Acetyltransferase (GNAT) domain
EPNMAIED_00757 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
EPNMAIED_00758 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EPNMAIED_00759 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
EPNMAIED_00760 2e-71 divIC D Septum formation initiator
EPNMAIED_00761 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
EPNMAIED_00762 4.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
EPNMAIED_00764 9.5e-71 P Major Facilitator Superfamily
EPNMAIED_00765 1.8e-91
EPNMAIED_00766 6.5e-284 sdaA 4.3.1.17 E Serine dehydratase alpha chain
EPNMAIED_00767 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
EPNMAIED_00768 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
EPNMAIED_00769 2.7e-144 yplQ S Haemolysin-III related
EPNMAIED_00770 6e-277 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EPNMAIED_00771 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
EPNMAIED_00772 0.0 D FtsK/SpoIIIE family
EPNMAIED_00773 9.9e-169 K Cell envelope-related transcriptional attenuator domain
EPNMAIED_00775 5.7e-208 K Cell envelope-related transcriptional attenuator domain
EPNMAIED_00776 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
EPNMAIED_00777 0.0 S Glycosyl transferase, family 2
EPNMAIED_00778 9.7e-222
EPNMAIED_00779 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
EPNMAIED_00780 2.5e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
EPNMAIED_00781 8.5e-139 ctsW S Phosphoribosyl transferase domain
EPNMAIED_00782 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
EPNMAIED_00783 2e-129 T Response regulator receiver domain protein
EPNMAIED_00784 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EPNMAIED_00785 3e-102 carD K CarD-like/TRCF domain
EPNMAIED_00786 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
EPNMAIED_00787 1e-140 znuB U ABC 3 transport family
EPNMAIED_00788 2e-160 znuC P ATPases associated with a variety of cellular activities
EPNMAIED_00789 2e-173 P Zinc-uptake complex component A periplasmic
EPNMAIED_00790 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EPNMAIED_00791 4.1e-254 rpsA J Ribosomal protein S1
EPNMAIED_00792 1.5e-115 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EPNMAIED_00793 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPNMAIED_00794 5.4e-14 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
EPNMAIED_00795 3.5e-152 terC P Integral membrane protein, TerC family
EPNMAIED_00796 2.5e-305 pyk 2.7.1.40 G Pyruvate kinase
EPNMAIED_00798 2.9e-18 relB L RelB antitoxin
EPNMAIED_00800 7.2e-196 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
EPNMAIED_00801 3.2e-115 3.6.3.21 E ATPases associated with a variety of cellular activities
EPNMAIED_00802 1.4e-121 tcyA ET Bacterial periplasmic substrate-binding proteins
EPNMAIED_00803 8.2e-101 E Binding-protein-dependent transport system inner membrane component
EPNMAIED_00804 5.1e-37 pcrA1 3.6.4.12 F DNA helicase
EPNMAIED_00805 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
EPNMAIED_00806 2.6e-243 hsdM 2.1.1.72 V HsdM N-terminal domain
EPNMAIED_00807 1.6e-57 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
EPNMAIED_00808 9.2e-70 hsdS 3.1.21.3 V type i restriction
EPNMAIED_00809 8.4e-107 L Belongs to the 'phage' integrase family
EPNMAIED_00810 6.8e-164 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
EPNMAIED_00811 9.4e-101 pdtaR T Response regulator receiver domain protein
EPNMAIED_00812 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EPNMAIED_00813 1.7e-173 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
EPNMAIED_00814 1.5e-123 3.6.1.13 L NUDIX domain
EPNMAIED_00815 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EPNMAIED_00816 4.1e-212 ykiI
EPNMAIED_00818 7.8e-252 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
EPNMAIED_00819 0.0 S Psort location CytoplasmicMembrane, score 9.99
EPNMAIED_00820 6.2e-241 V ABC transporter permease
EPNMAIED_00821 3.9e-138 V ABC transporter
EPNMAIED_00822 5.1e-150 T HD domain
EPNMAIED_00823 1e-167 S Glutamine amidotransferase domain
EPNMAIED_00824 0.0 kup P Transport of potassium into the cell
EPNMAIED_00825 2.2e-184 tatD L TatD related DNase
EPNMAIED_00826 0.0 G Alpha-L-arabinofuranosidase C-terminus
EPNMAIED_00827 6.6e-233 G Alpha galactosidase A
EPNMAIED_00828 1.4e-223 K helix_turn _helix lactose operon repressor
EPNMAIED_00829 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
EPNMAIED_00830 1.8e-125
EPNMAIED_00831 0.0 yknV V ABC transporter
EPNMAIED_00832 0.0 mdlA2 V ABC transporter
EPNMAIED_00833 1.2e-205 lipA I Hydrolase, alpha beta domain protein
EPNMAIED_00834 5e-27 S Psort location Cytoplasmic, score 8.87
EPNMAIED_00835 3.8e-156 I alpha/beta hydrolase fold
EPNMAIED_00836 1.5e-230 M Protein of unknown function (DUF2961)
EPNMAIED_00837 3.2e-153 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00838 3.2e-159 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_00839 5.1e-256 G Bacterial extracellular solute-binding protein
EPNMAIED_00840 2.2e-190 K helix_turn _helix lactose operon repressor
EPNMAIED_00841 0.0 M probably involved in cell wall
EPNMAIED_00842 3.2e-250 3.2.1.14 GH18 S Carbohydrate binding domain
EPNMAIED_00843 0.0 T Diguanylate cyclase, GGDEF domain
EPNMAIED_00844 2.3e-187 lacR K Transcriptional regulator, LacI family
EPNMAIED_00845 1.7e-230 nagA 3.5.1.25 G Amidohydrolase family
EPNMAIED_00846 7.6e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
EPNMAIED_00847 0.0 G Glycosyl hydrolase family 20, domain 2
EPNMAIED_00848 1.9e-172 2.7.1.2 GK ROK family
EPNMAIED_00849 4.4e-164 G ABC transporter permease
EPNMAIED_00850 7.5e-147 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_00851 1.4e-27 G Bacterial extracellular solute-binding protein
EPNMAIED_00852 6.4e-196 G Bacterial extracellular solute-binding protein
EPNMAIED_00853 3.6e-210 GK ROK family
EPNMAIED_00854 2.6e-262 lacS G Psort location CytoplasmicMembrane, score 10.00
EPNMAIED_00855 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EPNMAIED_00856 6.6e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
EPNMAIED_00857 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
EPNMAIED_00858 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EPNMAIED_00859 6.6e-107
EPNMAIED_00860 6.1e-191 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EPNMAIED_00861 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
EPNMAIED_00862 9e-127 dedA S SNARE associated Golgi protein
EPNMAIED_00864 8.7e-130 S HAD hydrolase, family IA, variant 3
EPNMAIED_00865 8.6e-47
EPNMAIED_00866 4.5e-115 hspR K transcriptional regulator, MerR family
EPNMAIED_00867 1.5e-162 dnaJ1 O DnaJ molecular chaperone homology domain
EPNMAIED_00868 2.1e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EPNMAIED_00869 0.0 dnaK O Heat shock 70 kDa protein
EPNMAIED_00870 1.3e-145 S Mitochondrial biogenesis AIM24
EPNMAIED_00871 5.3e-47 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
EPNMAIED_00872 4.5e-121 S membrane transporter protein
EPNMAIED_00873 8.3e-193 K Psort location Cytoplasmic, score
EPNMAIED_00874 6e-129 traX S TraX protein
EPNMAIED_00875 3.5e-143 S HAD-hyrolase-like
EPNMAIED_00876 2.6e-294 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
EPNMAIED_00877 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
EPNMAIED_00878 1.7e-13 S Transposon-encoded protein TnpV
EPNMAIED_00879 2.2e-108 pepE 3.4.13.21 E Peptidase family S51
EPNMAIED_00880 6.5e-105 S Protein of unknown function, DUF624
EPNMAIED_00881 4e-153 rafG G ABC transporter permease
EPNMAIED_00882 3.7e-154 msmF G Binding-protein-dependent transport system inner membrane component
EPNMAIED_00883 3.2e-181 K Psort location Cytoplasmic, score
EPNMAIED_00884 1.8e-187 K Periplasmic binding protein-like domain
EPNMAIED_00885 1.4e-264 amyE G Bacterial extracellular solute-binding protein
EPNMAIED_00886 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
EPNMAIED_00887 4e-256 amyE G Bacterial extracellular solute-binding protein
EPNMAIED_00888 2.9e-136 G Phosphoglycerate mutase family
EPNMAIED_00889 1.9e-62 S Protein of unknown function (DUF4235)
EPNMAIED_00890 1e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
EPNMAIED_00891 1.6e-44
EPNMAIED_00892 1.8e-83 K Cro/C1-type HTH DNA-binding domain
EPNMAIED_00893 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
EPNMAIED_00894 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EPNMAIED_00895 1.8e-122 S Short repeat of unknown function (DUF308)
EPNMAIED_00896 8.4e-36 manR K PRD domain
EPNMAIED_00897 4.5e-13 S Psort location Extracellular, score 8.82
EPNMAIED_00898 2.9e-232 EGP Major facilitator Superfamily
EPNMAIED_00899 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EPNMAIED_00900 2e-269 KLT Domain of unknown function (DUF4032)
EPNMAIED_00901 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
EPNMAIED_00902 1.2e-129 K LytTr DNA-binding domain
EPNMAIED_00903 9.1e-230 T GHKL domain
EPNMAIED_00904 1.7e-71
EPNMAIED_00905 1.2e-215 clcA_2 P Voltage gated chloride channel
EPNMAIED_00906 6.1e-49 S Psort location Cytoplasmic, score
EPNMAIED_00907 3.8e-137
EPNMAIED_00908 3.4e-159 3.4.22.70 M Sortase family
EPNMAIED_00909 2.8e-115 M LPXTG-motif cell wall anchor domain protein
EPNMAIED_00910 0.0 S LPXTG-motif cell wall anchor domain protein
EPNMAIED_00911 3.9e-72 S GtrA-like protein
EPNMAIED_00912 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
EPNMAIED_00913 3.5e-118 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
EPNMAIED_00914 7.1e-77 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
EPNMAIED_00915 3.4e-112 vex2 V ABC transporter, ATP-binding protein
EPNMAIED_00916 2.9e-213 vex1 V Efflux ABC transporter, permease protein
EPNMAIED_00917 3.4e-242 vex3 V ABC transporter permease
EPNMAIED_00918 6.1e-25 G Major facilitator Superfamily
EPNMAIED_00919 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EPNMAIED_00920 1.4e-181 lacR K Transcriptional regulator, LacI family
EPNMAIED_00921 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
EPNMAIED_00922 4e-167 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
EPNMAIED_00923 4.3e-160 S Amidohydrolase
EPNMAIED_00924 3.8e-145 IQ KR domain
EPNMAIED_00925 2.3e-245 4.2.1.68 M Enolase C-terminal domain-like
EPNMAIED_00926 4.4e-266 G Bacterial extracellular solute-binding protein
EPNMAIED_00927 1.1e-175 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00928 1.1e-156 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_00929 5.4e-192 K Bacterial regulatory proteins, lacI family
EPNMAIED_00930 2.3e-53 lacZ5 3.2.1.23 G beta-galactosidase activity
EPNMAIED_00931 4.9e-262 G Bacterial extracellular solute-binding protein
EPNMAIED_00932 2.2e-169 K helix_turn _helix lactose operon repressor
EPNMAIED_00933 2.9e-168 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_00934 1.4e-149 G ABC transporter permease
EPNMAIED_00935 4.1e-11 S Psort location Extracellular, score 8.82
EPNMAIED_00936 0.0 trxB1 1.8.1.9 C Thioredoxin domain
EPNMAIED_00937 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
EPNMAIED_00938 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
EPNMAIED_00939 0.0 KLT Protein tyrosine kinase
EPNMAIED_00940 7.5e-151 O Thioredoxin
EPNMAIED_00942 5.7e-89 S G5
EPNMAIED_00943 7.8e-143 L IstB-like ATP binding protein
EPNMAIED_00944 7.1e-198 L PFAM Integrase catalytic
EPNMAIED_00945 4.2e-32 ltrBE1 U Relaxase/Mobilisation nuclease domain
EPNMAIED_00946 3.2e-54 ltrBE1 U Relaxase/Mobilisation nuclease domain
EPNMAIED_00947 3.3e-28 S Bacterial mobilisation protein (MobC)
EPNMAIED_00949 0.0 V Type II restriction enzyme, methylase subunits
EPNMAIED_00954 2.1e-101
EPNMAIED_00955 1.9e-10
EPNMAIED_00956 6.6e-119 L Phage integrase, N-terminal SAM-like domain
EPNMAIED_00958 7.4e-51 EGP Major facilitator Superfamily
EPNMAIED_00959 5.3e-94 EGP Major facilitator Superfamily
EPNMAIED_00960 2.3e-37 yxeN P amino acid ABC transporter
EPNMAIED_00961 4.3e-36 E Binding-protein-dependent transport system inner membrane component
EPNMAIED_00962 6.2e-73 3.6.3.21 E ABC transporter
EPNMAIED_00963 3e-68 odh 1.5.1.28 I glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EPNMAIED_00964 2.3e-18 ET Bacterial periplasmic substrate-binding proteins
EPNMAIED_00965 5.6e-238 bglA 3.2.1.21 G Glycosyl hydrolase family 1
EPNMAIED_00966 8.7e-159 U Binding-protein-dependent transport system inner membrane component
EPNMAIED_00967 1e-162 U Binding-protein-dependent transport system inner membrane component
EPNMAIED_00968 5.6e-239 malE G Bacterial extracellular solute-binding protein
EPNMAIED_00969 6.7e-204 rbsR K helix_turn _helix lactose operon repressor
EPNMAIED_00972 1.1e-63 ydhQ 2.7.11.1 MU cell adhesion
EPNMAIED_00976 9.4e-10 S Helix-turn-helix domain
EPNMAIED_00977 1.8e-59 S Helix-turn-helix domain
EPNMAIED_00979 1.5e-181 L Phage integrase family
EPNMAIED_00980 6.3e-38
EPNMAIED_00988 7.9e-11
EPNMAIED_00991 1.3e-10
EPNMAIED_00993 1.9e-81 L helicase
EPNMAIED_00994 1e-150 recQ 3.6.4.12, 5.99.1.2 F RecQ zinc-binding
EPNMAIED_00996 1.2e-161 S Fic/DOC family
EPNMAIED_00997 1.3e-47 L PFAM Integrase catalytic
EPNMAIED_00998 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
EPNMAIED_00999 1.2e-154 ypfH S Phospholipase/Carboxylesterase
EPNMAIED_01000 0.0 yjcE P Sodium/hydrogen exchanger family
EPNMAIED_01001 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
EPNMAIED_01002 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
EPNMAIED_01003 8.4e-229 nagC GK ROK family
EPNMAIED_01004 6.9e-245 msmE7 G Bacterial extracellular solute-binding protein
EPNMAIED_01005 1.2e-158 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_01006 2.6e-155 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_01007 3.3e-26
EPNMAIED_01008 3.1e-15 S COG NOG14600 non supervised orthologous group
EPNMAIED_01009 5.2e-65 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
EPNMAIED_01010 1e-75 yiaC K Acetyltransferase (GNAT) domain
EPNMAIED_01011 9.7e-25
EPNMAIED_01012 5.6e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
EPNMAIED_01013 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
EPNMAIED_01014 2.7e-302 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
EPNMAIED_01015 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EPNMAIED_01016 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
EPNMAIED_01017 4.7e-244 pbuX F Permease family
EPNMAIED_01018 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
EPNMAIED_01019 0.0 pcrA 3.6.4.12 L DNA helicase
EPNMAIED_01020 1.4e-60 S Domain of unknown function (DUF4418)
EPNMAIED_01021 1.4e-215 V FtsX-like permease family
EPNMAIED_01022 5.4e-150 lolD V ABC transporter
EPNMAIED_01023 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EPNMAIED_01024 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
EPNMAIED_01025 5.6e-129 pgm3 G Phosphoglycerate mutase family
EPNMAIED_01026 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
EPNMAIED_01027 2.5e-36
EPNMAIED_01028 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EPNMAIED_01029 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EPNMAIED_01030 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EPNMAIED_01031 9.3e-57 3.4.23.43 S Type IV leader peptidase family
EPNMAIED_01032 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EPNMAIED_01033 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EPNMAIED_01034 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
EPNMAIED_01035 9.4e-54 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
EPNMAIED_01036 4.1e-53 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
EPNMAIED_01037 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
EPNMAIED_01038 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
EPNMAIED_01039 0.0 S L,D-transpeptidase catalytic domain
EPNMAIED_01040 8.1e-290 sufB O FeS assembly protein SufB
EPNMAIED_01041 1.5e-233 sufD O FeS assembly protein SufD
EPNMAIED_01042 1e-142 sufC O FeS assembly ATPase SufC
EPNMAIED_01043 1e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EPNMAIED_01044 3.4e-100 iscU C SUF system FeS assembly protein, NifU family
EPNMAIED_01045 3e-107 yitW S Iron-sulfur cluster assembly protein
EPNMAIED_01046 6.8e-242 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EPNMAIED_01047 1.7e-162 spoU 2.1.1.185 J SpoU rRNA Methylase family
EPNMAIED_01049 6.5e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
EPNMAIED_01050 5.3e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
EPNMAIED_01051 5.9e-208 phoH T PhoH-like protein
EPNMAIED_01052 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EPNMAIED_01053 1.2e-250 corC S CBS domain
EPNMAIED_01054 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EPNMAIED_01055 0.0 fadD 6.2.1.3 I AMP-binding enzyme
EPNMAIED_01056 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
EPNMAIED_01057 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
EPNMAIED_01058 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EPNMAIED_01059 3.6e-268 S Psort location Cytoplasmic, score 8.87
EPNMAIED_01061 3.5e-225 G Transmembrane secretion effector
EPNMAIED_01062 5.4e-121 K Bacterial regulatory proteins, tetR family
EPNMAIED_01063 1.1e-39 nrdH O Glutaredoxin
EPNMAIED_01064 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
EPNMAIED_01065 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPNMAIED_01067 8.2e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EPNMAIED_01068 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EPNMAIED_01069 2.6e-30 EGP Major facilitator Superfamily
EPNMAIED_01070 1.3e-25 yhjX EGP Major facilitator Superfamily
EPNMAIED_01071 8.5e-195 S alpha beta
EPNMAIED_01072 1e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EPNMAIED_01073 4.8e-93 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPNMAIED_01074 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EPNMAIED_01075 7.7e-73 K Acetyltransferase (GNAT) domain
EPNMAIED_01077 1.9e-227 ilvE 2.6.1.42 E Amino-transferase class IV
EPNMAIED_01078 1.1e-133 S UPF0126 domain
EPNMAIED_01079 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
EPNMAIED_01080 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
EPNMAIED_01081 3e-234 hemN H Involved in the biosynthesis of porphyrin-containing compound
EPNMAIED_01082 5e-145 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
EPNMAIED_01083 1.5e-288 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
EPNMAIED_01084 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
EPNMAIED_01085 2.5e-234 F Psort location CytoplasmicMembrane, score 10.00
EPNMAIED_01086 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
EPNMAIED_01087 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
EPNMAIED_01088 2e-74
EPNMAIED_01089 2.2e-248 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
EPNMAIED_01090 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
EPNMAIED_01091 1.8e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
EPNMAIED_01092 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
EPNMAIED_01093 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EPNMAIED_01094 1.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
EPNMAIED_01095 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
EPNMAIED_01096 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
EPNMAIED_01097 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
EPNMAIED_01098 5.2e-278 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
EPNMAIED_01099 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
EPNMAIED_01100 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
EPNMAIED_01101 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
EPNMAIED_01102 5.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPNMAIED_01103 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
EPNMAIED_01104 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EPNMAIED_01105 8.8e-109 J Acetyltransferase (GNAT) domain
EPNMAIED_01106 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EPNMAIED_01107 5.6e-219 yxjG_1 E Psort location Cytoplasmic, score 8.87
EPNMAIED_01108 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
EPNMAIED_01109 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
EPNMAIED_01110 2.3e-139 S SdpI/YhfL protein family
EPNMAIED_01111 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
EPNMAIED_01112 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EPNMAIED_01113 5e-125 XK27_06785 V ABC transporter
EPNMAIED_01115 2.7e-17
EPNMAIED_01120 3.2e-17 S Helix-turn-helix domain
EPNMAIED_01121 1.7e-15 S Transcription factor WhiB
EPNMAIED_01124 8e-31 parA D VirC1 protein
EPNMAIED_01126 3.4e-22
EPNMAIED_01127 4.5e-49
EPNMAIED_01128 8.9e-38
EPNMAIED_01129 0.0 XK27_00515 D Cell surface antigen C-terminus
EPNMAIED_01130 7.5e-253 U Spy0128-like isopeptide containing domain
EPNMAIED_01132 2.3e-20
EPNMAIED_01133 1.2e-09
EPNMAIED_01134 3.1e-33
EPNMAIED_01135 1.7e-29
EPNMAIED_01136 1.4e-143
EPNMAIED_01137 4.4e-187
EPNMAIED_01138 2.2e-200 traD S COG0433 Predicted ATPase
EPNMAIED_01141 4.8e-07
EPNMAIED_01142 5.1e-23
EPNMAIED_01143 1.5e-229 U TraM recognition site of TraD and TraG
EPNMAIED_01144 3.4e-47 S Domain of unknown function (DUF4913)
EPNMAIED_01145 2.1e-40
EPNMAIED_01147 2.2e-86 2.7.11.1 S HipA-like C-terminal domain
EPNMAIED_01148 9.7e-138 L PFAM Relaxase mobilization nuclease family protein
EPNMAIED_01149 1.9e-144 S Fic/DOC family
EPNMAIED_01150 2.3e-112 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
EPNMAIED_01151 2.9e-70 ecoRIIR 3.1.21.4 L EcoRII C terminal
EPNMAIED_01152 4.1e-16 K Bacterial mobilisation protein (MobC)
EPNMAIED_01155 2.9e-240 topB 5.99.1.2 L DNA topoisomerase
EPNMAIED_01158 1.7e-67
EPNMAIED_01159 5.1e-84 M G5 domain protein
EPNMAIED_01160 2.5e-07
EPNMAIED_01161 1e-55 ard S Antirestriction protein (ArdA)
EPNMAIED_01163 1.1e-227 2.7.7.7 L Transposase and inactivated derivatives
EPNMAIED_01164 1e-156 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
EPNMAIED_01165 4.4e-111
EPNMAIED_01166 1.1e-227 2.7.7.7 L Transposase and inactivated derivatives
EPNMAIED_01168 2.7e-102 S Fic/DOC family
EPNMAIED_01169 1.6e-87 K Psort location Cytoplasmic, score
EPNMAIED_01170 1.8e-130 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
EPNMAIED_01172 6.4e-176 xerH L Phage integrase family
EPNMAIED_01174 1.6e-61
EPNMAIED_01175 3.3e-96 M Peptidase family M23
EPNMAIED_01176 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
EPNMAIED_01177 3.1e-268 G ABC transporter substrate-binding protein
EPNMAIED_01178 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
EPNMAIED_01179 1.1e-209 guaB 1.1.1.205 F IMP dehydrogenase family protein
EPNMAIED_01180 8e-108 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
EPNMAIED_01181 4.5e-71 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
EPNMAIED_01182 2.9e-241 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EPNMAIED_01183 3.1e-66 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
EPNMAIED_01184 6.2e-142 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EPNMAIED_01185 2.1e-117
EPNMAIED_01187 1.1e-63 L Phage integrase family
EPNMAIED_01191 1.4e-41 D FtsK/SpoIIIE family
EPNMAIED_01195 4.1e-142 S Protein conserved in bacteria
EPNMAIED_01196 4.5e-233 XK27_00240 K Fic/DOC family
EPNMAIED_01197 2.7e-70 pdxH S Pfam:Pyridox_oxidase
EPNMAIED_01198 2.7e-302 M domain protein
EPNMAIED_01199 8.1e-82 3.4.22.70 M Sortase family
EPNMAIED_01200 5.7e-64 3.4.22.70 M Sortase family
EPNMAIED_01201 2.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
EPNMAIED_01202 5.7e-172 corA P CorA-like Mg2+ transporter protein
EPNMAIED_01203 1.5e-142 ET Bacterial periplasmic substrate-binding proteins
EPNMAIED_01204 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
EPNMAIED_01205 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
EPNMAIED_01206 0.0 comE S Competence protein
EPNMAIED_01207 6.5e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
EPNMAIED_01208 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
EPNMAIED_01209 1.3e-148 yeaZ 2.3.1.234 O Glycoprotease family
EPNMAIED_01210 2.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
EPNMAIED_01211 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EPNMAIED_01213 2.6e-119 yoaP E YoaP-like
EPNMAIED_01214 4.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
EPNMAIED_01215 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
EPNMAIED_01216 6.7e-72 K MerR family regulatory protein
EPNMAIED_01217 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
EPNMAIED_01218 2e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
EPNMAIED_01219 2.7e-221 yxjG_1 E Psort location Cytoplasmic, score 8.87
EPNMAIED_01220 3.6e-76 S Psort location CytoplasmicMembrane, score
EPNMAIED_01221 1e-182 cat P Cation efflux family
EPNMAIED_01224 7.4e-113
EPNMAIED_01225 3.7e-152
EPNMAIED_01226 9.8e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
EPNMAIED_01227 2.5e-280 pepC 3.4.22.40 E Peptidase C1-like family
EPNMAIED_01228 1.2e-120 S IMP dehydrogenase activity
EPNMAIED_01229 1.9e-300 ybiT S ABC transporter
EPNMAIED_01230 4.7e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
EPNMAIED_01231 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EPNMAIED_01233 2e-13
EPNMAIED_01234 6.9e-274 S Psort location Cytoplasmic, score 8.87
EPNMAIED_01235 9.5e-141 S Domain of unknown function (DUF4194)
EPNMAIED_01236 0.0 S Psort location Cytoplasmic, score 8.87
EPNMAIED_01237 3.2e-220 S Psort location Cytoplasmic, score 8.87
EPNMAIED_01238 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
EPNMAIED_01239 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
EPNMAIED_01240 6e-182 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
EPNMAIED_01241 1.1e-170 rapZ S Displays ATPase and GTPase activities
EPNMAIED_01242 1.3e-171 whiA K May be required for sporulation
EPNMAIED_01243 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
EPNMAIED_01244 1.6e-148 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
EPNMAIED_01245 2.4e-32 secG U Preprotein translocase SecG subunit
EPNMAIED_01246 3.3e-163 S Sucrose-6F-phosphate phosphohydrolase
EPNMAIED_01247 2.6e-299 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
EPNMAIED_01248 6.2e-10 pnuC H Nicotinamide mononucleotide transporter
EPNMAIED_01249 1.7e-28 pnuC H Nicotinamide mononucleotide transporter
EPNMAIED_01250 1.4e-62 pnuC H Nicotinamide mononucleotide transporter
EPNMAIED_01251 1.2e-32 nadR H ATPase kinase involved in NAD metabolism
EPNMAIED_01252 1.6e-39 nadR H ATPase kinase involved in NAD metabolism
EPNMAIED_01253 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EPNMAIED_01254 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
EPNMAIED_01255 4.7e-197 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
EPNMAIED_01256 4.7e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
EPNMAIED_01257 5.1e-158 G Fructosamine kinase
EPNMAIED_01258 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
EPNMAIED_01259 1.6e-156 S PAC2 family
EPNMAIED_01264 9.4e-36
EPNMAIED_01265 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
EPNMAIED_01266 9.7e-112 K helix_turn_helix, mercury resistance
EPNMAIED_01267 4.6e-61
EPNMAIED_01268 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
EPNMAIED_01269 1.1e-61 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
EPNMAIED_01270 0.0 helY L DEAD DEAH box helicase
EPNMAIED_01271 2.1e-54
EPNMAIED_01272 0.0 pafB K WYL domain
EPNMAIED_01273 3.7e-265 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
EPNMAIED_01275 3.1e-69
EPNMAIED_01276 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
EPNMAIED_01277 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
EPNMAIED_01278 2.4e-138 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
EPNMAIED_01279 8.2e-34
EPNMAIED_01280 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
EPNMAIED_01281 3e-246
EPNMAIED_01282 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EPNMAIED_01283 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
EPNMAIED_01284 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EPNMAIED_01285 9.4e-60 yajC U Preprotein translocase subunit
EPNMAIED_01286 2.8e-199 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
EPNMAIED_01287 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
EPNMAIED_01288 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EPNMAIED_01289 5.2e-128 yebC K transcriptional regulatory protein
EPNMAIED_01290 1.8e-100 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
EPNMAIED_01291 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EPNMAIED_01292 6.5e-140 S Bacterial protein of unknown function (DUF881)
EPNMAIED_01293 4.2e-45 sbp S Protein of unknown function (DUF1290)
EPNMAIED_01294 1.7e-171 S Bacterial protein of unknown function (DUF881)
EPNMAIED_01295 1.4e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPNMAIED_01296 1.9e-155 hisG 2.4.2.17 F ATP phosphoribosyltransferase
EPNMAIED_01297 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
EPNMAIED_01298 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
EPNMAIED_01299 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EPNMAIED_01300 8.4e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
EPNMAIED_01301 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
EPNMAIED_01302 1.4e-292 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EPNMAIED_01303 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EPNMAIED_01304 1.5e-138 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
EPNMAIED_01305 8.2e-221 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
EPNMAIED_01306 7.5e-175 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
EPNMAIED_01307 7.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
EPNMAIED_01308 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
EPNMAIED_01310 8.5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EPNMAIED_01311 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
EPNMAIED_01312 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPNMAIED_01313 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
EPNMAIED_01314 1.8e-121
EPNMAIED_01315 4.7e-157 mltE2 M Bacteriophage peptidoglycan hydrolase
EPNMAIED_01318 3.5e-102
EPNMAIED_01319 3.2e-206
EPNMAIED_01320 2.4e-45
EPNMAIED_01325 1.8e-46
EPNMAIED_01326 5.1e-37
EPNMAIED_01327 3.6e-27
EPNMAIED_01328 7.2e-105
EPNMAIED_01331 1.7e-67
EPNMAIED_01332 0.0 XK27_00515 D Cell surface antigen C-terminus
EPNMAIED_01333 8.6e-22 M domain protein
EPNMAIED_01336 1.8e-256 U Type IV secretory pathway, VirB4
EPNMAIED_01339 1.7e-287 U TraM recognition site of TraD and TraG
EPNMAIED_01344 1e-47
EPNMAIED_01346 2.6e-23 S Bacterial toxin of type II toxin-antitoxin system, YafQ
EPNMAIED_01347 2.9e-52 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
EPNMAIED_01348 3.2e-272 V N-6 DNA Methylase
EPNMAIED_01349 4.4e-82 pin L Resolvase, N terminal domain
EPNMAIED_01351 1.3e-60 V Psort location Cytoplasmic, score
EPNMAIED_01352 8e-38
EPNMAIED_01354 4e-42
EPNMAIED_01356 1.2e-77
EPNMAIED_01358 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EPNMAIED_01361 2.1e-20
EPNMAIED_01363 2.4e-197 topB 5.99.1.2 L DNA topoisomerase
EPNMAIED_01365 4.2e-76 XK27_08505 D nucleotidyltransferase activity
EPNMAIED_01366 9.2e-37 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
EPNMAIED_01367 1e-30 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
EPNMAIED_01368 2.3e-32
EPNMAIED_01369 0.0 traA 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
EPNMAIED_01370 6.6e-07
EPNMAIED_01371 2.8e-62
EPNMAIED_01372 2.1e-38 S Fic/DOC family
EPNMAIED_01373 1.8e-52 L single-stranded DNA binding
EPNMAIED_01375 1.6e-98 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
EPNMAIED_01376 2.5e-95 S Protein of unknown function (DUF2786)
EPNMAIED_01381 6.8e-24
EPNMAIED_01382 8.3e-47 VY92_07350 S Phage derived protein Gp49-like (DUF891)
EPNMAIED_01383 3.8e-32 K Helix-turn-helix domain
EPNMAIED_01385 1.5e-24 S Domain of unknown function (DUF3846)
EPNMAIED_01388 3.9e-09 3.1.21.4 L Restriction endonuclease XhoI
EPNMAIED_01389 4.2e-90 I alpha/beta hydrolase fold
EPNMAIED_01390 2.6e-143 cobB2 K Sir2 family
EPNMAIED_01391 2.7e-230 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
EPNMAIED_01392 5e-31 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
EPNMAIED_01393 5.3e-11 L DNA restriction-modification system
EPNMAIED_01395 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPNMAIED_01396 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EPNMAIED_01397 3.2e-101
EPNMAIED_01398 2.9e-243 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EPNMAIED_01399 6.5e-251 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EPNMAIED_01400 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
EPNMAIED_01401 4.6e-233 EGP Major facilitator Superfamily
EPNMAIED_01402 5e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
EPNMAIED_01403 2.1e-173 G Fic/DOC family
EPNMAIED_01404 2.2e-144
EPNMAIED_01405 9.1e-164 IQ Enoyl-(Acyl carrier protein) reductase
EPNMAIED_01406 5.3e-167 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPNMAIED_01407 2.3e-57 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPNMAIED_01409 9.5e-92 bcp 1.11.1.15 O Redoxin
EPNMAIED_01410 9.2e-29 S Psort location Cytoplasmic, score 8.87
EPNMAIED_01411 1.6e-94 S Pyridoxamine 5'-phosphate oxidase
EPNMAIED_01412 0.0 S Histidine phosphatase superfamily (branch 2)
EPNMAIED_01413 7.9e-44 L transposition
EPNMAIED_01414 1.1e-23 C Acetamidase/Formamidase family
EPNMAIED_01415 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
EPNMAIED_01416 2.3e-173 V ATPases associated with a variety of cellular activities
EPNMAIED_01417 7.9e-118 S ABC-2 family transporter protein
EPNMAIED_01418 4.4e-123 S Haloacid dehalogenase-like hydrolase
EPNMAIED_01419 1.4e-261 recN L May be involved in recombinational repair of damaged DNA
EPNMAIED_01420 4.4e-177 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EPNMAIED_01421 3.1e-262 trkB P Cation transport protein
EPNMAIED_01422 3e-116 trkA P TrkA-N domain
EPNMAIED_01423 1.5e-68 K RNA polymerase sigma factor, sigma-70 family
EPNMAIED_01424 3.9e-53 yjdF S Protein of unknown function (DUF2992)
EPNMAIED_01425 6.4e-64 K Transcriptional regulator PadR-like family
EPNMAIED_01426 5e-60 K Psort location Cytoplasmic, score
EPNMAIED_01427 9.3e-125 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
EPNMAIED_01428 7.5e-186 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
EPNMAIED_01429 7e-150 L Tetratricopeptide repeat
EPNMAIED_01430 5e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EPNMAIED_01431 0.0 S Protein of unknown function (DUF975)
EPNMAIED_01432 8.6e-137 S Putative ABC-transporter type IV
EPNMAIED_01433 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
EPNMAIED_01434 1.3e-279 argH 4.3.2.1 E argininosuccinate lyase
EPNMAIED_01435 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
EPNMAIED_01436 1.9e-84 argR K Regulates arginine biosynthesis genes
EPNMAIED_01437 7.1e-186 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EPNMAIED_01438 1e-240 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
EPNMAIED_01439 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
EPNMAIED_01440 8.8e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EPNMAIED_01441 5e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EPNMAIED_01442 3.5e-97
EPNMAIED_01443 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
EPNMAIED_01444 5.9e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EPNMAIED_01446 2.7e-94 yvdD 3.2.2.10 S Possible lysine decarboxylase
EPNMAIED_01447 2.9e-17
EPNMAIED_01449 1.5e-17 L HNH endonuclease
EPNMAIED_01450 8.3e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
EPNMAIED_01451 4e-42 V DNA modification
EPNMAIED_01452 7.8e-282 glnA 6.3.1.2 E glutamine synthetase
EPNMAIED_01453 6e-143 S Domain of unknown function (DUF4191)
EPNMAIED_01454 8.4e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EPNMAIED_01455 3.6e-93 S Protein of unknown function (DUF3043)
EPNMAIED_01456 1.9e-253 argE E Peptidase dimerisation domain
EPNMAIED_01457 1.4e-145 cbiQ P Cobalt transport protein
EPNMAIED_01458 1.8e-265 ykoD P ATPases associated with a variety of cellular activities
EPNMAIED_01459 2.2e-84 ykoE S ABC-type cobalt transport system, permease component
EPNMAIED_01460 2.4e-212 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
EPNMAIED_01461 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EPNMAIED_01462 0.0 S Tetratricopeptide repeat
EPNMAIED_01463 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EPNMAIED_01464 8.1e-307 2.8.2.22 S Arylsulfotransferase Ig-like domain
EPNMAIED_01465 1.9e-144 bioM P ATPases associated with a variety of cellular activities
EPNMAIED_01466 8.1e-221 E Aminotransferase class I and II
EPNMAIED_01467 1.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
EPNMAIED_01468 6.3e-201 S Glycosyltransferase, group 2 family protein
EPNMAIED_01469 1.8e-144 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EPNMAIED_01470 2.4e-47 yhbY J CRS1_YhbY
EPNMAIED_01471 0.0 ecfA GP ABC transporter, ATP-binding protein
EPNMAIED_01472 3.9e-108 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
EPNMAIED_01473 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
EPNMAIED_01474 5.1e-39 pepC 3.4.22.40 E homocysteine catabolic process
EPNMAIED_01475 1.3e-113 kcsA U Ion channel
EPNMAIED_01476 1.1e-186 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
EPNMAIED_01477 6.6e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
EPNMAIED_01478 1.2e-123 3.2.1.8 S alpha beta
EPNMAIED_01479 6.7e-45 S Protein of unknown function DUF262
EPNMAIED_01480 0.0 S Protein of unknown function DUF262
EPNMAIED_01483 9.2e-08 E Zn peptidase
EPNMAIED_01484 2.1e-14
EPNMAIED_01487 2.8e-27 S AAA domain, putative AbiEii toxin, Type IV TA system
EPNMAIED_01488 9.7e-28 S AAA domain, putative AbiEii toxin, Type IV TA system
EPNMAIED_01489 0.0 L UvrD-like helicase C-terminal domain
EPNMAIED_01490 0.0 L DEAD-like helicases superfamily
EPNMAIED_01491 0.0 V Type II restriction enzyme, methylase
EPNMAIED_01492 0.0 hepA L SNF2 family N-terminal domain
EPNMAIED_01493 2.4e-102 K Psort location Cytoplasmic, score
EPNMAIED_01494 5.7e-53
EPNMAIED_01495 3.8e-207
EPNMAIED_01496 1.2e-148 S phosphoesterase or phosphohydrolase
EPNMAIED_01497 5.6e-82 4.1.1.44 S Cupin domain
EPNMAIED_01498 6e-167 C Aldo/keto reductase family
EPNMAIED_01499 2.9e-128 E Psort location Cytoplasmic, score 8.87
EPNMAIED_01500 7.7e-132 yebE S DUF218 domain
EPNMAIED_01501 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
EPNMAIED_01502 2e-236 rnd 3.1.13.5 J 3'-5' exonuclease
EPNMAIED_01503 9.9e-80 S Protein of unknown function (DUF3000)
EPNMAIED_01504 7.4e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPNMAIED_01505 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
EPNMAIED_01506 4.5e-31
EPNMAIED_01507 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EPNMAIED_01508 1.2e-224 S Peptidase dimerisation domain
EPNMAIED_01509 1.7e-156 S Sucrose-6F-phosphate phosphohydrolase
EPNMAIED_01510 4.8e-146 metQ P NLPA lipoprotein
EPNMAIED_01511 2.1e-146 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EPNMAIED_01512 6.8e-111 metI P Binding-protein-dependent transport system inner membrane component
EPNMAIED_01513 1.1e-74
EPNMAIED_01515 4.3e-237 L Phage integrase family
EPNMAIED_01517 1.7e-16 3.1.21.4 L Restriction endonuclease XhoI
EPNMAIED_01518 1.8e-15 3.1.21.4 L Restriction endonuclease XhoI
EPNMAIED_01519 5.2e-224 S HipA-like C-terminal domain
EPNMAIED_01520 4.2e-07 3.1.21.4 V restriction endonuclease
EPNMAIED_01521 9.6e-175 S Fic/DOC family
EPNMAIED_01522 1e-67
EPNMAIED_01523 1.3e-64
EPNMAIED_01524 2.2e-68
EPNMAIED_01526 0.0 topB 5.99.1.2 L DNA topoisomerase
EPNMAIED_01527 4.5e-55
EPNMAIED_01528 1.2e-30
EPNMAIED_01530 2.1e-44 S Domain of unknown function (DUF4160)
EPNMAIED_01531 2.5e-42 K Protein of unknown function (DUF2442)
EPNMAIED_01532 1.5e-43 S Bacterial mobilisation protein (MobC)
EPNMAIED_01533 2.9e-248 ltrBE1 U Relaxase/Mobilisation nuclease domain
EPNMAIED_01534 3.8e-161 S Protein of unknown function (DUF3801)
EPNMAIED_01535 9.8e-277
EPNMAIED_01536 0.0 XK27_00500 KL Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EPNMAIED_01537 2.5e-36
EPNMAIED_01538 1.5e-33
EPNMAIED_01539 0.0 U Type IV secretory system Conjugative DNA transfer
EPNMAIED_01541 1.4e-98 K Helix-turn-helix domain protein
EPNMAIED_01543 1.1e-65
EPNMAIED_01544 1.7e-96
EPNMAIED_01545 1.1e-213 isp2 3.2.1.96 M CHAP domain
EPNMAIED_01546 0.0 trsE U type IV secretory pathway VirB4
EPNMAIED_01547 9.7e-61 S PrgI family protein
EPNMAIED_01548 4.5e-136
EPNMAIED_01549 3.4e-25
EPNMAIED_01550 1.5e-143
EPNMAIED_01551 9.5e-39 M Listeria-Bacteroides repeat domain (List_Bact_rpt)
EPNMAIED_01555 1.2e-18
EPNMAIED_01556 5.5e-113 parA D AAA domain
EPNMAIED_01557 1.9e-81 S Transcription factor WhiB
EPNMAIED_01558 1e-35
EPNMAIED_01559 1.2e-181 S Helix-turn-helix domain
EPNMAIED_01560 8e-15
EPNMAIED_01561 3.3e-26
EPNMAIED_01562 5.6e-119
EPNMAIED_01563 2.4e-65
EPNMAIED_01564 5.1e-07
EPNMAIED_01565 6.6e-135 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EPNMAIED_01566 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EPNMAIED_01567 8.5e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
EPNMAIED_01568 1e-47 S Domain of unknown function (DUF4193)
EPNMAIED_01569 4.1e-147 S Protein of unknown function (DUF3071)
EPNMAIED_01570 3e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
EPNMAIED_01571 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
EPNMAIED_01572 0.0 lhr L DEAD DEAH box helicase
EPNMAIED_01573 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
EPNMAIED_01574 2.4e-79 S Protein of unknown function (DUF2975)
EPNMAIED_01575 6.6e-243 T PhoQ Sensor
EPNMAIED_01576 6.9e-223 G Major Facilitator Superfamily
EPNMAIED_01577 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
EPNMAIED_01578 9.7e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
EPNMAIED_01579 9.5e-118
EPNMAIED_01580 2.2e-196 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
EPNMAIED_01581 0.0 pknL 2.7.11.1 KLT PASTA
EPNMAIED_01582 1.9e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
EPNMAIED_01583 1.4e-96
EPNMAIED_01584 6.5e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EPNMAIED_01585 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
EPNMAIED_01586 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EPNMAIED_01587 3.5e-123 recX S Modulates RecA activity
EPNMAIED_01588 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EPNMAIED_01589 4.3e-46 S Protein of unknown function (DUF3046)
EPNMAIED_01590 1.6e-80 K Helix-turn-helix XRE-family like proteins
EPNMAIED_01591 5.5e-98 cinA 3.5.1.42 S Belongs to the CinA family
EPNMAIED_01592 1.3e-122 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EPNMAIED_01593 0.0 ftsK D FtsK SpoIIIE family protein
EPNMAIED_01594 1.9e-192 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EPNMAIED_01595 1e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EPNMAIED_01596 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
EPNMAIED_01597 1.8e-176 ydeD EG EamA-like transporter family
EPNMAIED_01598 1.7e-127 ybhL S Belongs to the BI1 family
EPNMAIED_01599 7.4e-59 S Domain of unknown function (DUF5067)
EPNMAIED_01600 5.1e-243 T Histidine kinase
EPNMAIED_01601 1.8e-127 K helix_turn_helix, Lux Regulon
EPNMAIED_01602 0.0 S Protein of unknown function DUF262
EPNMAIED_01603 2.6e-115 K helix_turn_helix, Lux Regulon
EPNMAIED_01604 1.2e-244 T Histidine kinase
EPNMAIED_01605 4.4e-191 V ATPases associated with a variety of cellular activities
EPNMAIED_01606 7.7e-225 V ABC-2 family transporter protein
EPNMAIED_01607 8.9e-229 V ABC-2 family transporter protein
EPNMAIED_01608 3e-206 rhaR1 K helix_turn_helix, arabinose operon control protein
EPNMAIED_01609 5.2e-108 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
EPNMAIED_01610 9.9e-250 VP1224 V Psort location CytoplasmicMembrane, score 9.99
EPNMAIED_01611 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EPNMAIED_01612 0.0 ctpE P E1-E2 ATPase
EPNMAIED_01613 1.5e-98
EPNMAIED_01614 6.3e-243 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EPNMAIED_01615 2.4e-133 S Protein of unknown function (DUF3159)
EPNMAIED_01616 1.7e-151 S Protein of unknown function (DUF3710)
EPNMAIED_01617 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
EPNMAIED_01618 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
EPNMAIED_01619 4.1e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
EPNMAIED_01620 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
EPNMAIED_01621 0.0 E ABC transporter, substrate-binding protein, family 5
EPNMAIED_01622 0.0 E ABC transporter, substrate-binding protein, family 5
EPNMAIED_01623 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
EPNMAIED_01624 5.2e-08
EPNMAIED_01625 2.8e-34
EPNMAIED_01626 8.9e-195 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
EPNMAIED_01627 1.3e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
EPNMAIED_01628 4e-104
EPNMAIED_01629 0.0 typA T Elongation factor G C-terminus
EPNMAIED_01630 1.1e-248 naiP U Sugar (and other) transporter
EPNMAIED_01631 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
EPNMAIED_01632 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
EPNMAIED_01633 2e-177 xerD D recombinase XerD
EPNMAIED_01634 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EPNMAIED_01635 2.1e-25 rpmI J Ribosomal protein L35
EPNMAIED_01636 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EPNMAIED_01637 4.9e-110 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
EPNMAIED_01638 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
EPNMAIED_01639 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EPNMAIED_01640 3.9e-171 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EPNMAIED_01641 4.3e-188 galM 5.1.3.3 G Aldose 1-epimerase
EPNMAIED_01642 3.5e-36
EPNMAIED_01643 1.3e-97 sigH K Belongs to the sigma-70 factor family. ECF subfamily
EPNMAIED_01644 2.7e-280 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPNMAIED_01645 2.5e-186 V Acetyltransferase (GNAT) domain
EPNMAIED_01646 2.5e-289 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
EPNMAIED_01647 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
EPNMAIED_01648 5.8e-94 3.6.1.55 F NUDIX domain
EPNMAIED_01649 0.0 P Belongs to the ABC transporter superfamily
EPNMAIED_01650 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
EPNMAIED_01651 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
EPNMAIED_01652 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
EPNMAIED_01653 1.7e-218 GK ROK family
EPNMAIED_01654 1.1e-164 2.7.1.4 G pfkB family carbohydrate kinase
EPNMAIED_01655 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
EPNMAIED_01656 1.6e-27
EPNMAIED_01657 8.4e-248 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
EPNMAIED_01658 2.3e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
EPNMAIED_01659 2.3e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
EPNMAIED_01660 6.3e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EPNMAIED_01661 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
EPNMAIED_01662 2.1e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EPNMAIED_01663 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EPNMAIED_01664 6.4e-263 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
EPNMAIED_01665 1.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EPNMAIED_01666 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
EPNMAIED_01667 1.8e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EPNMAIED_01668 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
EPNMAIED_01669 1.6e-91 mraZ K Belongs to the MraZ family
EPNMAIED_01670 0.0 L DNA helicase
EPNMAIED_01671 8.7e-218 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
EPNMAIED_01672 8.5e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EPNMAIED_01673 2.3e-53 M Lysin motif
EPNMAIED_01674 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EPNMAIED_01675 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EPNMAIED_01676 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
EPNMAIED_01677 1.1e-270 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EPNMAIED_01678 1.9e-112 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
EPNMAIED_01679 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
EPNMAIED_01680 1.4e-190
EPNMAIED_01681 5.5e-156 V N-Acetylmuramoyl-L-alanine amidase
EPNMAIED_01682 1.7e-80
EPNMAIED_01683 8.5e-119 ytrE V ATPases associated with a variety of cellular activities
EPNMAIED_01684 5.5e-220 EGP Major facilitator Superfamily
EPNMAIED_01685 3.6e-139 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
EPNMAIED_01686 5.6e-219 S Domain of unknown function (DUF5067)
EPNMAIED_01687 3.1e-264 glnA2 6.3.1.2 E glutamine synthetase
EPNMAIED_01688 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
EPNMAIED_01689 4.1e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EPNMAIED_01690 1.5e-122
EPNMAIED_01691 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
EPNMAIED_01692 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EPNMAIED_01693 2.4e-259 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EPNMAIED_01694 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
EPNMAIED_01695 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
EPNMAIED_01696 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EPNMAIED_01697 4.5e-31 3.1.21.3 V DivIVA protein
EPNMAIED_01698 6.9e-41 yggT S YGGT family
EPNMAIED_01699 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
EPNMAIED_01700 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EPNMAIED_01701 1.9e-244 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EPNMAIED_01702 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
EPNMAIED_01703 1e-105 S Pilus assembly protein, PilO
EPNMAIED_01704 8.1e-166 pilN NU PFAM Fimbrial assembly family protein
EPNMAIED_01705 8.7e-190 pilM NU Type IV pilus assembly protein PilM;
EPNMAIED_01706 2.4e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
EPNMAIED_01707 0.0
EPNMAIED_01708 7.3e-231 pilC U Type II secretion system (T2SS), protein F
EPNMAIED_01709 2.4e-46 pilA NU Prokaryotic N-terminal methylation motif
EPNMAIED_01710 2.1e-104 S Prokaryotic N-terminal methylation motif
EPNMAIED_01711 5.4e-136 ppdC NU Prokaryotic N-terminal methylation motif
EPNMAIED_01712 0.0 pulE NU Type II/IV secretion system protein
EPNMAIED_01713 0.0 pilT NU Type II/IV secretion system protein
EPNMAIED_01714 0.0
EPNMAIED_01715 2.2e-154 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EPNMAIED_01716 1.1e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
EPNMAIED_01717 2.9e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
EPNMAIED_01718 3e-60 S Thiamine-binding protein
EPNMAIED_01719 1.1e-192 K helix_turn _helix lactose operon repressor
EPNMAIED_01720 2.8e-241 lacY P LacY proton/sugar symporter
EPNMAIED_01721 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
EPNMAIED_01722 1.4e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_01723 9.1e-206 P NMT1/THI5 like
EPNMAIED_01724 2.1e-217 iunH1 3.2.2.1 F nucleoside hydrolase
EPNMAIED_01725 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EPNMAIED_01726 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
EPNMAIED_01727 0.0 I acetylesterase activity
EPNMAIED_01728 9.5e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EPNMAIED_01729 5.3e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
EPNMAIED_01730 4.6e-227 2.7.11.1 NU Tfp pilus assembly protein FimV
EPNMAIED_01732 6.5e-75 S Protein of unknown function (DUF3052)
EPNMAIED_01733 1.4e-156 lon T Belongs to the peptidase S16 family
EPNMAIED_01734 3.3e-294 S Zincin-like metallopeptidase
EPNMAIED_01735 3.6e-282 uvrD2 3.6.4.12 L DNA helicase
EPNMAIED_01736 1.8e-268 mphA S Aminoglycoside phosphotransferase
EPNMAIED_01737 3.6e-32 S Protein of unknown function (DUF3107)
EPNMAIED_01738 5e-173 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
EPNMAIED_01739 4.8e-117 S Vitamin K epoxide reductase
EPNMAIED_01740 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
EPNMAIED_01741 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
EPNMAIED_01742 3.5e-21 S Patatin-like phospholipase
EPNMAIED_01743 2.3e-311 E ABC transporter, substrate-binding protein, family 5
EPNMAIED_01744 4.9e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
EPNMAIED_01745 1.9e-155 S Patatin-like phospholipase
EPNMAIED_01746 7.4e-186 K LysR substrate binding domain protein
EPNMAIED_01747 2.1e-240 patB 4.4.1.8 E Aminotransferase, class I II
EPNMAIED_01748 6.1e-120 S Phospholipase/Carboxylesterase
EPNMAIED_01749 9.3e-33 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPNMAIED_01750 7.6e-154 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
EPNMAIED_01751 1.8e-95 cas4 3.1.12.1 L Domain of unknown function DUF83
EPNMAIED_01752 1.1e-143 cas7c L CRISPR-associated protein Cas7
EPNMAIED_01753 2e-218 csd1 S CRISPR-associated protein (Cas_Csd1)
EPNMAIED_01754 2.8e-101 cas5d S CRISPR-associated protein (Cas_Cas5)
EPNMAIED_01755 2.9e-302 L DEAD-like helicases superfamily
EPNMAIED_01756 3.3e-125 S Fic/DOC family
EPNMAIED_01757 1.1e-18 S Fic/DOC family
EPNMAIED_01758 4.7e-88 S Phospholipase/Carboxylesterase
EPNMAIED_01760 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EPNMAIED_01761 8.7e-257 lacS G Psort location CytoplasmicMembrane, score 10.00
EPNMAIED_01762 2.8e-185 lacR K Transcriptional regulator, LacI family
EPNMAIED_01763 0.0 V ABC transporter transmembrane region
EPNMAIED_01764 0.0 V ABC transporter, ATP-binding protein
EPNMAIED_01765 3.2e-98 K MarR family
EPNMAIED_01766 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
EPNMAIED_01767 2.8e-105 K Bacterial regulatory proteins, tetR family
EPNMAIED_01768 9.5e-201 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
EPNMAIED_01769 6.4e-182 G Transporter major facilitator family protein
EPNMAIED_01770 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
EPNMAIED_01771 1.3e-214 EGP Major facilitator Superfamily
EPNMAIED_01772 2.2e-116 K Periplasmic binding protein domain
EPNMAIED_01773 4.3e-14 K helix_turn_helix, mercury resistance
EPNMAIED_01774 8.8e-220 lmrB U Major Facilitator Superfamily
EPNMAIED_01775 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
EPNMAIED_01776 5.4e-110 K Bacterial regulatory proteins, tetR family
EPNMAIED_01777 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
EPNMAIED_01778 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
EPNMAIED_01779 1.9e-233 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
EPNMAIED_01780 4.1e-237 G Transporter major facilitator family protein
EPNMAIED_01781 4.4e-104 K Bacterial regulatory proteins, tetR family
EPNMAIED_01782 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
EPNMAIED_01783 1.9e-115 K Bacterial regulatory proteins, tetR family
EPNMAIED_01784 4.4e-252 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
EPNMAIED_01785 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
EPNMAIED_01786 3.9e-156 hgdC I BadF/BadG/BcrA/BcrD ATPase family
EPNMAIED_01787 1.6e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EPNMAIED_01788 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
EPNMAIED_01789 8.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPNMAIED_01790 7e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
EPNMAIED_01792 2.5e-195 S Endonuclease/Exonuclease/phosphatase family
EPNMAIED_01793 4.6e-43 V ATPases associated with a variety of cellular activities
EPNMAIED_01794 3.8e-23
EPNMAIED_01795 3.4e-22 M cell wall anchor domain protein
EPNMAIED_01796 2.9e-99 tmp1 S Domain of unknown function (DUF4391)
EPNMAIED_01797 6.7e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
EPNMAIED_01798 2.5e-233 aspB E Aminotransferase class-V
EPNMAIED_01799 1.5e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
EPNMAIED_01800 2.4e-184 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
EPNMAIED_01801 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
EPNMAIED_01802 3.4e-21 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
EPNMAIED_01803 7.8e-221 L Psort location Cytoplasmic, score 8.87
EPNMAIED_01804 4.1e-71 L Transposase IS200 like
EPNMAIED_01805 1.6e-301 KL Domain of unknown function (DUF3427)
EPNMAIED_01806 1.5e-76
EPNMAIED_01807 2e-71 S Bacterial PH domain
EPNMAIED_01808 2.4e-245 S zinc finger
EPNMAIED_01809 1.7e-290 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
EPNMAIED_01810 5.2e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
EPNMAIED_01811 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EPNMAIED_01812 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
EPNMAIED_01814 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EPNMAIED_01815 9.5e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EPNMAIED_01816 0.0 pacS 3.6.3.54 P E1-E2 ATPase
EPNMAIED_01817 1.1e-38 csoR S Metal-sensitive transcriptional repressor
EPNMAIED_01818 1.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
EPNMAIED_01819 2.3e-246 G Major Facilitator Superfamily
EPNMAIED_01820 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
EPNMAIED_01821 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
EPNMAIED_01822 6.8e-262 KLT Protein tyrosine kinase
EPNMAIED_01823 0.0 S Fibronectin type 3 domain
EPNMAIED_01824 1.2e-231 S ATPase family associated with various cellular activities (AAA)
EPNMAIED_01825 8.3e-221 S Protein of unknown function DUF58
EPNMAIED_01826 0.0 E Transglutaminase-like superfamily
EPNMAIED_01827 5.8e-163 3.1.3.16 T Sigma factor PP2C-like phosphatases
EPNMAIED_01828 1.3e-104 B Belongs to the OprB family
EPNMAIED_01829 2.4e-101 T Forkhead associated domain
EPNMAIED_01830 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPNMAIED_01831 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EPNMAIED_01832 4.4e-99
EPNMAIED_01833 2.4e-178 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
EPNMAIED_01834 4.3e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
EPNMAIED_01835 2.1e-252 S UPF0210 protein
EPNMAIED_01836 7.1e-43 gcvR T Belongs to the UPF0237 family
EPNMAIED_01837 1.1e-23 lmrB EGP Major facilitator Superfamily
EPNMAIED_01838 9e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
EPNMAIED_01839 1.1e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
EPNMAIED_01840 3.4e-141 glpR K DeoR C terminal sensor domain
EPNMAIED_01841 2.8e-226 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
EPNMAIED_01842 1.4e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
EPNMAIED_01843 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
EPNMAIED_01844 2.3e-133 glxR K helix_turn_helix, cAMP Regulatory protein
EPNMAIED_01845 7.7e-216 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
EPNMAIED_01846 2.9e-86 J TM2 domain
EPNMAIED_01847 8.4e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
EPNMAIED_01848 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
EPNMAIED_01849 2.1e-235 S Uncharacterized conserved protein (DUF2183)
EPNMAIED_01850 2.7e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
EPNMAIED_01851 8.7e-209 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
EPNMAIED_01852 1.4e-158 mhpC I Alpha/beta hydrolase family
EPNMAIED_01853 3.5e-114 F Domain of unknown function (DUF4916)
EPNMAIED_01854 3.9e-60 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
EPNMAIED_01855 1.6e-169 S G5
EPNMAIED_01856 2.1e-88
EPNMAIED_01858 2.1e-262 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
EPNMAIED_01859 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
EPNMAIED_01860 6.5e-148 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_01861 1.7e-162 P Binding-protein-dependent transport system inner membrane component
EPNMAIED_01862 6.6e-270 G Bacterial extracellular solute-binding protein
EPNMAIED_01863 1.4e-184 K Psort location Cytoplasmic, score
EPNMAIED_01864 2.4e-181 K helix_turn _helix lactose operon repressor
EPNMAIED_01865 2e-77 G Bacterial extracellular solute-binding protein
EPNMAIED_01866 3.1e-98 G Bacterial extracellular solute-binding protein
EPNMAIED_01867 1.4e-162 G PFAM binding-protein-dependent transport systems inner membrane component
EPNMAIED_01868 6.6e-145 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_01869 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
EPNMAIED_01870 4.9e-55 yccF S Inner membrane component domain
EPNMAIED_01871 1e-107 S Psort location CytoplasmicMembrane, score 9.99
EPNMAIED_01872 8.2e-115 ysdA S Protein of unknown function (DUF1294)
EPNMAIED_01873 3.2e-29 S AAA domain, putative AbiEii toxin, Type IV TA system
EPNMAIED_01875 2e-53
EPNMAIED_01877 8.2e-31 S enterobacterial common antigen metabolic process
EPNMAIED_01878 4.5e-103 S enterobacterial common antigen metabolic process
EPNMAIED_01879 3.9e-170 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EPNMAIED_01880 2e-261 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
EPNMAIED_01881 8.1e-196 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPNMAIED_01882 6.5e-204 cps2J S Polysaccharide biosynthesis protein
EPNMAIED_01883 5.2e-288 menD 2.2.1.9 H Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
EPNMAIED_01884 8.9e-124 IQ Enoyl-(Acyl carrier protein) reductase
EPNMAIED_01885 3.4e-174 S slime layer polysaccharide biosynthetic process
EPNMAIED_01886 5.2e-51
EPNMAIED_01887 2.6e-76 GT2 M Glycosyl transferase, group 2 family protein
EPNMAIED_01888 7.2e-185 rgpAc GT4 M Domain of unknown function (DUF1972)
EPNMAIED_01889 4.6e-17 tnp7109-21 L Integrase core domain
EPNMAIED_01890 1.5e-102 L PFAM Integrase catalytic
EPNMAIED_01891 3.6e-37 L Psort location Cytoplasmic, score 8.87
EPNMAIED_01892 3.2e-66 L Integrase core domain
EPNMAIED_01893 6.7e-15 L Transposase, Mutator family
EPNMAIED_01894 4e-50 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
EPNMAIED_01896 1.5e-154
EPNMAIED_01897 3e-16
EPNMAIED_01898 2.4e-190 wcoI DM Psort location CytoplasmicMembrane, score
EPNMAIED_01899 1.8e-222 pflA S Protein of unknown function (DUF4012)
EPNMAIED_01900 2e-85 3.1.3.48 T Low molecular weight phosphatase family
EPNMAIED_01901 4.2e-181 S Endonuclease/Exonuclease/phosphatase family
EPNMAIED_01902 1.3e-46
EPNMAIED_01903 8.9e-284 EGP Major facilitator Superfamily
EPNMAIED_01904 2.1e-241 T Diguanylate cyclase (GGDEF) domain protein
EPNMAIED_01905 2.1e-116 L Protein of unknown function (DUF1524)
EPNMAIED_01906 9.3e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
EPNMAIED_01907 2.1e-241 mntH P H( )-stimulated, divalent metal cation uptake system
EPNMAIED_01908 8.9e-198 K helix_turn _helix lactose operon repressor
EPNMAIED_01909 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
EPNMAIED_01910 1.6e-164 G ABC transporter permease
EPNMAIED_01911 2.3e-165 G Binding-protein-dependent transport system inner membrane component
EPNMAIED_01912 1.1e-256 G Bacterial extracellular solute-binding protein
EPNMAIED_01913 5.2e-114 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
EPNMAIED_01914 1.2e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
EPNMAIED_01915 0.0 cydD V ABC transporter transmembrane region
EPNMAIED_01916 0.0 fadD 6.2.1.3 I AMP-binding enzyme
EPNMAIED_01917 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
EPNMAIED_01918 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
EPNMAIED_01919 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
EPNMAIED_01920 4e-209 K helix_turn _helix lactose operon repressor
EPNMAIED_01921 1.7e-284 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
EPNMAIED_01922 3.2e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
EPNMAIED_01923 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
EPNMAIED_01924 5.9e-299 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
EPNMAIED_01925 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
EPNMAIED_01926 4.8e-271 mmuP E amino acid
EPNMAIED_01927 8e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
EPNMAIED_01929 4.7e-122 cyaA 4.6.1.1 S CYTH
EPNMAIED_01930 1.2e-169 trxA2 O Tetratricopeptide repeat
EPNMAIED_01931 5e-179
EPNMAIED_01932 1.6e-195
EPNMAIED_01933 2e-148 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
EPNMAIED_01934 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
EPNMAIED_01935 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
EPNMAIED_01936 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EPNMAIED_01937 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EPNMAIED_01938 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EPNMAIED_01939 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPNMAIED_01940 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EPNMAIED_01941 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EPNMAIED_01942 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
EPNMAIED_01943 4.5e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EPNMAIED_01945 4.1e-94 L Phage integrase family
EPNMAIED_01946 2.4e-43 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
EPNMAIED_01947 7.2e-38
EPNMAIED_01948 2.2e-28 S Putative phage holin Dp-1
EPNMAIED_01949 4e-109 M Glycosyl hydrolases family 25
EPNMAIED_01950 3.5e-17
EPNMAIED_01952 5.3e-85 L reverse transcriptase
EPNMAIED_01953 6.4e-136
EPNMAIED_01954 4.3e-39
EPNMAIED_01957 4.7e-198 S Prophage endopeptidase tail
EPNMAIED_01958 5.2e-70 S phage tail
EPNMAIED_01959 3.2e-83 NT phage tail tape measure protein
EPNMAIED_01960 1e-29
EPNMAIED_01961 5.8e-28
EPNMAIED_01962 4.7e-60 eae N domain, Protein
EPNMAIED_01963 2.4e-22
EPNMAIED_01964 3.4e-08
EPNMAIED_01965 6.5e-30
EPNMAIED_01966 1e-46 S Phage protein Gp19/Gp15/Gp42
EPNMAIED_01968 3.3e-145 V Phage capsid family
EPNMAIED_01969 7.4e-28
EPNMAIED_01970 6.1e-168
EPNMAIED_01971 8.8e-183 S Phage portal protein, SPP1 Gp6-like
EPNMAIED_01972 2.8e-239 S Terminase
EPNMAIED_01973 1.4e-07
EPNMAIED_01974 2.6e-35 L HNH endonuclease
EPNMAIED_01976 5.8e-19
EPNMAIED_01981 1.6e-07
EPNMAIED_01987 4.2e-41 S Protein of unknwon function (DUF3310)
EPNMAIED_01990 1.1e-19 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
EPNMAIED_01991 7.5e-33 V HNH endonuclease
EPNMAIED_01994 4.1e-08
EPNMAIED_01995 2.8e-51 ssb1 L single-stranded DNA-binding protein
EPNMAIED_02000 8.3e-40 O prohibitin homologues
EPNMAIED_02005 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
EPNMAIED_02006 3.7e-191 yfdV S Membrane transport protein
EPNMAIED_02007 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
EPNMAIED_02008 1.6e-174 M LPXTG-motif cell wall anchor domain protein
EPNMAIED_02009 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
EPNMAIED_02010 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EPNMAIED_02011 9.4e-98 mntP P Probably functions as a manganese efflux pump
EPNMAIED_02012 4.9e-134
EPNMAIED_02013 4.9e-134 KT Transcriptional regulatory protein, C terminal
EPNMAIED_02014 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EPNMAIED_02015 7.1e-289 E Bacterial extracellular solute-binding proteins, family 5 Middle
EPNMAIED_02016 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
EPNMAIED_02017 0.0 S domain protein
EPNMAIED_02018 1e-69 tyrA 5.4.99.5 E Chorismate mutase type II
EPNMAIED_02019 3.5e-85 K helix_turn_helix ASNC type
EPNMAIED_02020 1.9e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EPNMAIED_02021 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
EPNMAIED_02022 2.1e-51 S Protein of unknown function (DUF2469)
EPNMAIED_02023 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
EPNMAIED_02024 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPNMAIED_02025 1.1e-286 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
EPNMAIED_02026 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EPNMAIED_02027 6.2e-134 K Psort location Cytoplasmic, score
EPNMAIED_02028 3.1e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
EPNMAIED_02029 2.7e-104 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EPNMAIED_02030 5.4e-168 rmuC S RmuC family
EPNMAIED_02031 6.8e-135 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
EPNMAIED_02032 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
EPNMAIED_02033 1.7e-162 fahA Q Fumarylacetoacetate (FAA) hydrolase family
EPNMAIED_02034 6.5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EPNMAIED_02035 2.5e-80
EPNMAIED_02036 7.4e-211 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
EPNMAIED_02037 1.3e-83 M Protein of unknown function (DUF3152)
EPNMAIED_02038 9.2e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
EPNMAIED_02040 1.7e-70 rplI J Binds to the 23S rRNA
EPNMAIED_02041 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EPNMAIED_02042 9.7e-70 ssb1 L Single-stranded DNA-binding protein
EPNMAIED_02043 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
EPNMAIED_02044 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EPNMAIED_02045 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EPNMAIED_02046 1.1e-259 EGP Major Facilitator Superfamily
EPNMAIED_02047 4.7e-166 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
EPNMAIED_02048 1.1e-197 K helix_turn _helix lactose operon repressor
EPNMAIED_02049 1.6e-61
EPNMAIED_02050 6.4e-232 S AAA domain
EPNMAIED_02051 1e-201 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
EPNMAIED_02052 4.4e-307 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
EPNMAIED_02053 3.7e-64 S oligosaccharyl transferase activity
EPNMAIED_02054 1e-131 ykoT 2.4.1.83 GT2 M Glycosyl transferase family 2
EPNMAIED_02055 3.2e-207 1.1.1.22 M UDP binding domain
EPNMAIED_02056 0.0 wbbM M Glycosyl transferase family 8
EPNMAIED_02057 1.1e-137 rgpC U Transport permease protein
EPNMAIED_02058 1.3e-171 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
EPNMAIED_02059 7.1e-36 M Glycosyltransferase like family 2
EPNMAIED_02060 0.0 wbbM M Glycosyl transferase family 8
EPNMAIED_02061 1e-94
EPNMAIED_02063 5.2e-45 M Glycosyl transferase family 2
EPNMAIED_02064 6.2e-62 M Glycosyl transferase family 2
EPNMAIED_02065 4.6e-56 M Glycosyl transferases group 1
EPNMAIED_02066 1.5e-83 S enterobacterial common antigen metabolic process
EPNMAIED_02068 4.1e-82 lytC 3.2.1.17, 3.2.1.96, 3.2.1.97 GH101 M Glycosyl hydrolases family 25
EPNMAIED_02069 1.8e-34 lytC 3.2.1.17, 3.2.1.96, 3.2.1.97 GH101 M Glycosyl hydrolases family 25
EPNMAIED_02070 3.7e-36 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
EPNMAIED_02071 4.4e-258 S AAA domain
EPNMAIED_02072 6.6e-70
EPNMAIED_02073 1e-10
EPNMAIED_02074 1.3e-299 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
EPNMAIED_02075 2.8e-58
EPNMAIED_02077 5.7e-25 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
EPNMAIED_02078 6.1e-16 S BrnA antitoxin of type II toxin-antitoxin system
EPNMAIED_02079 5.2e-43 K Cro/C1-type HTH DNA-binding domain
EPNMAIED_02080 2.1e-15

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)