ORF_ID e_value Gene_name EC_number CAZy COGs Description
KLIOFDBM_00001 1.2e-243 bglA 3.2.1.21 G Glycosyl hydrolase family 1
KLIOFDBM_00002 8e-160 U Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00003 2.7e-163 malC U Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00004 3.5e-241 malE G Bacterial extracellular solute-binding protein
KLIOFDBM_00005 9e-217 rbsR K helix_turn _helix lactose operon repressor
KLIOFDBM_00006 4.4e-21
KLIOFDBM_00008 1.6e-60 S EamA-like transporter family
KLIOFDBM_00009 2.5e-20 S EamA-like transporter family
KLIOFDBM_00010 1.4e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KLIOFDBM_00011 5.7e-222 dapC E Aminotransferase class I and II
KLIOFDBM_00012 2.9e-59 fdxA C 4Fe-4S binding domain
KLIOFDBM_00013 1.4e-268 E aromatic amino acid transport protein AroP K03293
KLIOFDBM_00014 1.3e-213 murB 1.3.1.98 M Cell wall formation
KLIOFDBM_00015 4.1e-25 rpmG J Ribosomal protein L33
KLIOFDBM_00019 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLIOFDBM_00020 1.6e-134
KLIOFDBM_00021 2.6e-85 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
KLIOFDBM_00022 7.3e-56 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
KLIOFDBM_00023 4.3e-31 fmdB S Putative regulatory protein
KLIOFDBM_00024 7e-93 flgA NO SAF
KLIOFDBM_00025 4.8e-28 L Superfamily I DNA and RNA helicases and helicase subunits
KLIOFDBM_00026 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
KLIOFDBM_00027 3.8e-185 T Forkhead associated domain
KLIOFDBM_00028 9.3e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KLIOFDBM_00029 2.4e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLIOFDBM_00030 6.4e-145 3.2.1.8 S alpha beta
KLIOFDBM_00031 1.1e-251 pbuO S Permease family
KLIOFDBM_00032 1.2e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLIOFDBM_00033 1.3e-171 pstA P Phosphate transport system permease
KLIOFDBM_00034 1.2e-156 pstC P probably responsible for the translocation of the substrate across the membrane
KLIOFDBM_00035 2.8e-202 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
KLIOFDBM_00036 3.8e-142 KT Transcriptional regulatory protein, C terminal
KLIOFDBM_00037 7.1e-205 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KLIOFDBM_00038 9.7e-239 EGP Sugar (and other) transporter
KLIOFDBM_00039 7.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLIOFDBM_00040 1.9e-236 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLIOFDBM_00041 4.1e-217 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KLIOFDBM_00042 4.1e-86 ebgC G YhcH YjgK YiaL family protein
KLIOFDBM_00043 0.0 ebgA 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KLIOFDBM_00044 4.8e-114 pgmB 5.4.2.6 S phosphonoacetaldehyde hydrolase activity
KLIOFDBM_00045 1.2e-155 EG EamA-like transporter family
KLIOFDBM_00046 0.0 kojP 2.4.1.230 GH65 G Glycosyl hydrolase family 65 central catalytic domain
KLIOFDBM_00047 5.7e-152 P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00048 2.6e-169 malC U Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00049 3.1e-237 G Bacterial extracellular solute-binding protein
KLIOFDBM_00050 4.6e-188 K Periplasmic binding protein domain
KLIOFDBM_00051 6.8e-99 U MarC family integral membrane protein
KLIOFDBM_00052 1.7e-262 pepC 3.4.22.40 E Peptidase C1-like family
KLIOFDBM_00053 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
KLIOFDBM_00054 8.9e-44 D nuclear chromosome segregation
KLIOFDBM_00055 2.6e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KLIOFDBM_00056 2.1e-149 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KLIOFDBM_00057 1.3e-196 yfiH Q Multi-copper polyphenol oxidoreductase laccase
KLIOFDBM_00058 4e-300 yegQ O Peptidase family U32 C-terminal domain
KLIOFDBM_00059 5.3e-178 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KLIOFDBM_00060 1.7e-102 rsmD 2.1.1.171 L Conserved hypothetical protein 95
KLIOFDBM_00061 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
KLIOFDBM_00062 2.5e-29 rpmB J Ribosomal L28 family
KLIOFDBM_00063 7.4e-194 yegV G pfkB family carbohydrate kinase
KLIOFDBM_00064 4.5e-236 yxiO S Vacuole effluxer Atg22 like
KLIOFDBM_00065 2.5e-130 K helix_turn_helix, mercury resistance
KLIOFDBM_00066 6.3e-69 T Toxic component of a toxin-antitoxin (TA) module
KLIOFDBM_00067 1.8e-53 relB L RelB antitoxin
KLIOFDBM_00068 2.3e-21 yxiO G Major facilitator Superfamily
KLIOFDBM_00069 7.5e-181 K Helix-turn-helix XRE-family like proteins
KLIOFDBM_00074 9.5e-46 XK27_04590 S NADPH-dependent FMN reductase
KLIOFDBM_00075 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
KLIOFDBM_00076 4.5e-294 pccB I Carboxyl transferase domain
KLIOFDBM_00077 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KLIOFDBM_00079 1.2e-90 bioY S BioY family
KLIOFDBM_00080 2.2e-163 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
KLIOFDBM_00081 0.0
KLIOFDBM_00082 3.2e-164 QT PucR C-terminal helix-turn-helix domain
KLIOFDBM_00083 2.7e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KLIOFDBM_00084 4e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLIOFDBM_00085 2.1e-145 K Psort location Cytoplasmic, score
KLIOFDBM_00086 7e-110 nusG K Participates in transcription elongation, termination and antitermination
KLIOFDBM_00087 1.4e-31 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KLIOFDBM_00089 3.8e-229 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
KLIOFDBM_00090 1.5e-215 G polysaccharide deacetylase
KLIOFDBM_00091 1.4e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLIOFDBM_00092 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLIOFDBM_00093 5.8e-39 rpmA J Ribosomal L27 protein
KLIOFDBM_00094 1.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
KLIOFDBM_00095 0.0 rne 3.1.26.12 J Ribonuclease E/G family
KLIOFDBM_00096 2.4e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
KLIOFDBM_00097 1.9e-167 mdcF S Transporter, auxin efflux carrier (AEC) family protein
KLIOFDBM_00098 1.7e-165 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
KLIOFDBM_00099 3.2e-149 S Amidohydrolase
KLIOFDBM_00100 5.4e-202 fucP G Major Facilitator Superfamily
KLIOFDBM_00101 2.8e-148 IQ KR domain
KLIOFDBM_00102 2.7e-249 4.2.1.68 M Enolase C-terminal domain-like
KLIOFDBM_00103 1.2e-191 K Bacterial regulatory proteins, lacI family
KLIOFDBM_00104 2e-221 V Efflux ABC transporter, permease protein
KLIOFDBM_00105 3.6e-130 V ATPases associated with a variety of cellular activities
KLIOFDBM_00106 7.2e-29 S Protein of unknown function (DUF1778)
KLIOFDBM_00107 3.2e-89 K Acetyltransferase (GNAT) family
KLIOFDBM_00108 9e-270 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
KLIOFDBM_00109 1.4e-185 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KLIOFDBM_00110 1.8e-237 hom 1.1.1.3 E Homoserine dehydrogenase
KLIOFDBM_00112 3.8e-231 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
KLIOFDBM_00113 2.5e-57 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KLIOFDBM_00114 1.5e-302 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KLIOFDBM_00115 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KLIOFDBM_00116 8.1e-131 K Bacterial regulatory proteins, tetR family
KLIOFDBM_00117 2.1e-222 G Transmembrane secretion effector
KLIOFDBM_00118 6.8e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLIOFDBM_00119 7.6e-255 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
KLIOFDBM_00120 2.1e-157 ET Bacterial periplasmic substrate-binding proteins
KLIOFDBM_00121 1.1e-119 ytmL P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00122 2.6e-138 P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00123 9.5e-103 S L-2-amino-thiazoline-4-carboxylic acid hydrolase
KLIOFDBM_00124 4.5e-132 yxeO 3.6.3.21 E ATPases associated with a variety of cellular activities
KLIOFDBM_00125 9e-220 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
KLIOFDBM_00126 4.3e-40 2.7.13.3 T Histidine kinase
KLIOFDBM_00127 2.5e-19 S Bacterial PH domain
KLIOFDBM_00128 9.3e-132 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KLIOFDBM_00129 4.2e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KLIOFDBM_00130 2.2e-140 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
KLIOFDBM_00131 2.8e-257 S Calcineurin-like phosphoesterase
KLIOFDBM_00132 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KLIOFDBM_00133 2.3e-233 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
KLIOFDBM_00134 4.7e-130
KLIOFDBM_00135 0.0 G N-terminal domain of (some) glycogen debranching enzymes
KLIOFDBM_00136 1.6e-49 P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00137 3.4e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLIOFDBM_00138 2.8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLIOFDBM_00139 3.7e-215 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KLIOFDBM_00140 2e-216 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLIOFDBM_00142 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KLIOFDBM_00143 1.2e-163 S Auxin Efflux Carrier
KLIOFDBM_00144 4e-158 fahA Q Fumarylacetoacetate (FAA) hydrolase family
KLIOFDBM_00145 9.2e-106 S Domain of unknown function (DUF4190)
KLIOFDBM_00146 5.1e-162
KLIOFDBM_00147 7.8e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
KLIOFDBM_00148 8.2e-64 K Helix-turn-helix domain
KLIOFDBM_00150 5.9e-47 5.3.1.27 G sugar phosphate isomerase involved in capsule formation
KLIOFDBM_00151 1.9e-57 G Branched-chain amino acid transport system / permease component
KLIOFDBM_00152 1.9e-72 P branched-chain amino acid ABC transporter, permease protein
KLIOFDBM_00153 1.1e-119 G ATPases associated with a variety of cellular activities
KLIOFDBM_00154 2.1e-79 G ABC-type sugar transport system periplasmic component
KLIOFDBM_00155 6.6e-167 xylB 1.1.1.57, 2.7.1.17 G Belongs to the FGGY kinase family
KLIOFDBM_00156 4.7e-76 xylR GK ROK family
KLIOFDBM_00157 5.5e-43
KLIOFDBM_00158 6.6e-53 S Helix-turn-helix domain
KLIOFDBM_00159 1.4e-20
KLIOFDBM_00160 2.6e-11
KLIOFDBM_00162 4.5e-161 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KLIOFDBM_00165 2.1e-262 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
KLIOFDBM_00166 1.2e-203 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
KLIOFDBM_00167 2.3e-178 3.4.14.13 M Glycosyltransferase like family 2
KLIOFDBM_00168 2.8e-272 S AI-2E family transporter
KLIOFDBM_00169 2.3e-234 epsG M Glycosyl transferase family 21
KLIOFDBM_00170 3.1e-190 natA V ATPases associated with a variety of cellular activities
KLIOFDBM_00171 4e-298
KLIOFDBM_00172 3.7e-250 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
KLIOFDBM_00173 1.5e-206 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KLIOFDBM_00174 2.7e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLIOFDBM_00175 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLIOFDBM_00177 5.8e-106 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
KLIOFDBM_00178 1.3e-159 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KLIOFDBM_00179 6.1e-263 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KLIOFDBM_00180 2.5e-92 S Protein of unknown function (DUF3180)
KLIOFDBM_00181 1.5e-169 tesB I Thioesterase-like superfamily
KLIOFDBM_00182 0.0 yjjK S ATP-binding cassette protein, ChvD family
KLIOFDBM_00183 2.8e-305 EGP Major Facilitator Superfamily
KLIOFDBM_00186 1.5e-177 glkA 2.7.1.2 G ROK family
KLIOFDBM_00187 3.4e-86 K Winged helix DNA-binding domain
KLIOFDBM_00188 1.5e-18 lmrB U Major Facilitator Superfamily
KLIOFDBM_00189 4.2e-166 dkgB S Oxidoreductase, aldo keto reductase family protein
KLIOFDBM_00190 5e-72 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KLIOFDBM_00191 2.4e-147
KLIOFDBM_00192 3.2e-66 yebQ EGP Major facilitator Superfamily
KLIOFDBM_00194 1.3e-36 rpmE J Binds the 23S rRNA
KLIOFDBM_00195 4.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLIOFDBM_00196 6.5e-154 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KLIOFDBM_00197 2.6e-206 livK E Receptor family ligand binding region
KLIOFDBM_00198 5.4e-111 U Belongs to the binding-protein-dependent transport system permease family
KLIOFDBM_00199 1e-188 livM U Belongs to the binding-protein-dependent transport system permease family
KLIOFDBM_00200 1.8e-161 E Branched-chain amino acid ATP-binding cassette transporter
KLIOFDBM_00201 3.3e-124 livF E ATPases associated with a variety of cellular activities
KLIOFDBM_00202 1.5e-118 ywlC 2.7.7.87 J Belongs to the SUA5 family
KLIOFDBM_00203 2.1e-211 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
KLIOFDBM_00204 4.8e-293 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KLIOFDBM_00205 4.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KLIOFDBM_00206 4.1e-267 recD2 3.6.4.12 L PIF1-like helicase
KLIOFDBM_00207 5.1e-258 S AMMECR1
KLIOFDBM_00208 1.7e-200 pflA 1.97.1.4 O Radical SAM superfamily
KLIOFDBM_00209 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KLIOFDBM_00210 2.2e-117 L Single-strand binding protein family
KLIOFDBM_00211 0.0 pepO 3.4.24.71 O Peptidase family M13
KLIOFDBM_00212 1e-138 S Short repeat of unknown function (DUF308)
KLIOFDBM_00213 6e-151 map 3.4.11.18 E Methionine aminopeptidase
KLIOFDBM_00214 7.8e-249 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
KLIOFDBM_00215 3.4e-146 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KLIOFDBM_00216 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
KLIOFDBM_00217 4.5e-100 XK27_03610 K Acetyltransferase (GNAT) domain
KLIOFDBM_00218 7.4e-88 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KLIOFDBM_00219 6.5e-201 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
KLIOFDBM_00220 1e-234 aspB E Aminotransferase class-V
KLIOFDBM_00221 2.9e-179 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KLIOFDBM_00222 1.6e-200 S Endonuclease/Exonuclease/phosphatase family
KLIOFDBM_00224 1.4e-77 F Nucleoside 2-deoxyribosyltransferase
KLIOFDBM_00225 8.8e-63 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KLIOFDBM_00226 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KLIOFDBM_00227 4.1e-95 ywrO 1.6.5.2 S Flavodoxin-like fold
KLIOFDBM_00228 3.7e-42 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLIOFDBM_00229 1.8e-256 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLIOFDBM_00230 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
KLIOFDBM_00231 7.7e-137 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLIOFDBM_00232 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
KLIOFDBM_00233 2.1e-254 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
KLIOFDBM_00234 2.1e-142 K Bacterial regulatory proteins, tetR family
KLIOFDBM_00235 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
KLIOFDBM_00237 1.6e-45 S Nucleotidyltransferase domain
KLIOFDBM_00238 1.3e-69 S Nucleotidyltransferase substrate binding protein like
KLIOFDBM_00239 1.6e-240 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
KLIOFDBM_00240 2.6e-37 zntA 3.6.3.3, 3.6.3.5 P Confers resistance to zinc, cadmium and lead. Couples the hydrolysis of ATP with the export of zinc, cadmium or lead, with highest activity when the metals are present as metal-thiolate complexes. Can also bind nickel, copper, cobalt and mercury
KLIOFDBM_00241 6.7e-25 msrA 1.8.4.11 O an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLIOFDBM_00242 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KLIOFDBM_00243 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KLIOFDBM_00244 2.1e-285 lsgC M transferase activity, transferring glycosyl groups
KLIOFDBM_00245 1.8e-234 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
KLIOFDBM_00246 7.4e-144 rgpC U Transport permease protein
KLIOFDBM_00247 0.0 rgpF M Rhamnan synthesis protein F
KLIOFDBM_00248 5.8e-183 M Glycosyltransferase like family 2
KLIOFDBM_00249 1.5e-29 M Glycosyltransferase like family 2
KLIOFDBM_00250 1.6e-171 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KLIOFDBM_00251 1.9e-288 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLIOFDBM_00252 1.2e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLIOFDBM_00253 0.0
KLIOFDBM_00254 5.6e-172 rfbJ M Glycosyl transferase family 2
KLIOFDBM_00255 1.7e-193 lytC 3.1.4.46, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
KLIOFDBM_00256 6.8e-230 K Cell envelope-related transcriptional attenuator domain
KLIOFDBM_00257 3.3e-256 V ABC transporter permease
KLIOFDBM_00258 8.1e-184 V ABC transporter
KLIOFDBM_00259 6e-140 T HD domain
KLIOFDBM_00260 1.8e-159 S Glutamine amidotransferase domain
KLIOFDBM_00261 0.0 kup P Transport of potassium into the cell
KLIOFDBM_00262 2e-185 tatD L TatD related DNase
KLIOFDBM_00263 0.0 yknV V ABC transporter
KLIOFDBM_00264 0.0 mdlA2 V ABC transporter
KLIOFDBM_00265 8.7e-270 S ATPase domain predominantly from Archaea
KLIOFDBM_00266 1.2e-252 S Domain of unknown function (DUF4143)
KLIOFDBM_00267 3.7e-192 G Glycosyl hydrolases family 43
KLIOFDBM_00268 1.4e-153 U Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00269 1.3e-176 U Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00270 1.8e-242 G Bacterial extracellular solute-binding protein
KLIOFDBM_00271 8.1e-196 K helix_turn _helix lactose operon repressor
KLIOFDBM_00272 0.0 lacZ 3.2.1.23 G Beta-galactosidase trimerisation domain
KLIOFDBM_00273 1.5e-266 S AAA domain
KLIOFDBM_00274 3.1e-54 EGP Major facilitator Superfamily
KLIOFDBM_00275 4e-34 EGP Major facilitator Superfamily
KLIOFDBM_00276 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
KLIOFDBM_00277 0.0 oppD P Belongs to the ABC transporter superfamily
KLIOFDBM_00278 3.2e-173 dppC EP N-terminal TM domain of oligopeptide transport permease C
KLIOFDBM_00279 1.8e-176 appB EP Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00280 1.2e-277 pepC 3.4.22.40 E Peptidase C1-like family
KLIOFDBM_00281 2.5e-46
KLIOFDBM_00282 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLIOFDBM_00283 9.4e-121
KLIOFDBM_00284 6.5e-182 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLIOFDBM_00286 1.1e-256 G MFS/sugar transport protein
KLIOFDBM_00287 8.1e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KLIOFDBM_00288 0.0 lmrA2 V ABC transporter transmembrane region
KLIOFDBM_00289 0.0 lmrA1 V ABC transporter, ATP-binding protein
KLIOFDBM_00290 1.2e-91 ydgJ K helix_turn_helix multiple antibiotic resistance protein
KLIOFDBM_00291 9.5e-278 cycA E Amino acid permease
KLIOFDBM_00292 0.0 V FtsX-like permease family
KLIOFDBM_00293 7.5e-129 V ABC transporter
KLIOFDBM_00294 3.8e-268 aroP E aromatic amino acid transport protein AroP K03293
KLIOFDBM_00295 1.1e-104 S Protein of unknown function, DUF624
KLIOFDBM_00296 6.8e-153 rafG G ABC transporter permease
KLIOFDBM_00297 4.4e-147 malC G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00298 5.3e-184 K Psort location Cytoplasmic, score
KLIOFDBM_00299 2.9e-254 amyE G Bacterial extracellular solute-binding protein
KLIOFDBM_00300 8.4e-136 G Phosphoglycerate mutase family
KLIOFDBM_00301 1.2e-59 S Protein of unknown function (DUF4235)
KLIOFDBM_00302 5.7e-138 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
KLIOFDBM_00303 0.0 pip S YhgE Pip domain protein
KLIOFDBM_00304 3.8e-278 pip S YhgE Pip domain protein
KLIOFDBM_00305 1.8e-40
KLIOFDBM_00306 2.3e-34 malT K Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3'
KLIOFDBM_00307 1.6e-271 aspA 4.3.1.1 E Fumarase C C-terminus
KLIOFDBM_00308 1.2e-135 M Mechanosensitive ion channel
KLIOFDBM_00309 3.7e-185 S CAAX protease self-immunity
KLIOFDBM_00310 9.7e-239 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KLIOFDBM_00311 6.9e-151 U Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00312 9.9e-161 U Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00313 2.9e-218 P Bacterial extracellular solute-binding protein
KLIOFDBM_00314 9.1e-228 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KLIOFDBM_00315 4.6e-180 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KLIOFDBM_00316 8.8e-189 plsC2 2.3.1.51 I Phosphate acyltransferases
KLIOFDBM_00317 3.6e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
KLIOFDBM_00320 6.9e-118 cyaA 4.6.1.1 S CYTH
KLIOFDBM_00321 1.1e-170 trxA2 O Tetratricopeptide repeat
KLIOFDBM_00322 2.5e-178
KLIOFDBM_00323 6.1e-179
KLIOFDBM_00324 3.6e-158 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
KLIOFDBM_00325 5.2e-130 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KLIOFDBM_00326 9.4e-49 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KLIOFDBM_00327 6.1e-282 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLIOFDBM_00328 6.1e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLIOFDBM_00329 1.3e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLIOFDBM_00330 3.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLIOFDBM_00331 1.8e-58 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KLIOFDBM_00332 1.7e-29 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLIOFDBM_00333 1.9e-144 atpB C it plays a direct role in the translocation of protons across the membrane
KLIOFDBM_00334 2.3e-206 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KLIOFDBM_00336 0.0 K RNA polymerase II activating transcription factor binding
KLIOFDBM_00337 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KLIOFDBM_00338 2.8e-90 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KLIOFDBM_00339 1.1e-96 mntP P Probably functions as a manganese efflux pump
KLIOFDBM_00340 1.1e-116
KLIOFDBM_00341 4e-139 KT Transcriptional regulatory protein, C terminal
KLIOFDBM_00342 5.7e-126 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLIOFDBM_00343 2.7e-280 E Bacterial extracellular solute-binding proteins, family 5 Middle
KLIOFDBM_00344 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KLIOFDBM_00345 0.0 S domain protein
KLIOFDBM_00346 1e-63 tyrA 5.4.99.5 E Chorismate mutase type II
KLIOFDBM_00347 5.4e-50 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
KLIOFDBM_00348 1.6e-35 L Helix-turn-helix domain
KLIOFDBM_00349 5.7e-21 L Helix-turn-helix domain
KLIOFDBM_00350 3.2e-131 rafA 3.2.1.22 G alpha-galactosidase
KLIOFDBM_00351 2.2e-114 araQ U Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00352 1.2e-120 lacF P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00353 2.8e-153 araN G Bacterial extracellular solute-binding protein
KLIOFDBM_00354 5.1e-50 K helix_turn_helix, arabinose operon control protein
KLIOFDBM_00355 5.5e-116 L Transposase
KLIOFDBM_00356 1.3e-46 pabC 2.6.1.42, 4.1.3.38 EH Amino-transferase class IV
KLIOFDBM_00357 3.3e-291 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KLIOFDBM_00358 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
KLIOFDBM_00359 3.3e-52 S Protein of unknown function (DUF2469)
KLIOFDBM_00360 4e-195 2.3.1.57 J Acetyltransferase (GNAT) domain
KLIOFDBM_00361 5.6e-283 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLIOFDBM_00362 4.6e-288 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KLIOFDBM_00363 4.1e-51 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLIOFDBM_00364 3.3e-160 K Psort location Cytoplasmic, score
KLIOFDBM_00365 4.5e-178
KLIOFDBM_00366 5.4e-167 V ABC transporter
KLIOFDBM_00367 6.2e-155 spoU 2.1.1.185 J RNA methyltransferase TrmH family
KLIOFDBM_00368 1.6e-109 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLIOFDBM_00369 1.6e-210 rmuC S RmuC family
KLIOFDBM_00370 9.6e-43 csoR S Metal-sensitive transcriptional repressor
KLIOFDBM_00371 0.0 pacS 1.9.3.1, 3.6.3.54 P E1-E2 ATPase
KLIOFDBM_00372 4e-117 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KLIOFDBM_00374 2.7e-71 rplI J Binds to the 23S rRNA
KLIOFDBM_00375 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KLIOFDBM_00376 6.8e-76 ssb1 L Single-stranded DNA-binding protein
KLIOFDBM_00377 4.6e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KLIOFDBM_00379 1.3e-89 lemA S LemA family
KLIOFDBM_00380 0.0 S Predicted membrane protein (DUF2207)
KLIOFDBM_00381 9.9e-12 S Predicted membrane protein (DUF2207)
KLIOFDBM_00382 8.2e-59 S Predicted membrane protein (DUF2207)
KLIOFDBM_00383 4.4e-58 S Predicted membrane protein (DUF2207)
KLIOFDBM_00384 3.1e-20
KLIOFDBM_00385 4.1e-169 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
KLIOFDBM_00386 1.9e-200 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KLIOFDBM_00387 6.4e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLIOFDBM_00388 1e-34 CP_0960 S Belongs to the UPF0109 family
KLIOFDBM_00389 7e-62 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KLIOFDBM_00390 4.2e-213 S Endonuclease/Exonuclease/phosphatase family
KLIOFDBM_00391 9e-266 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLIOFDBM_00392 2.3e-162 P Cation efflux family
KLIOFDBM_00393 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLIOFDBM_00394 7.1e-137 guaA1 6.3.5.2 F Peptidase C26
KLIOFDBM_00395 0.0 yjjK S ABC transporter
KLIOFDBM_00396 7.8e-73 vapC S Toxic component of a toxin-antitoxin (TA) module. An RNase
KLIOFDBM_00397 3.9e-44 stbC S Plasmid stability protein
KLIOFDBM_00398 1.5e-92 ilvN 2.2.1.6 E ACT domain
KLIOFDBM_00399 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
KLIOFDBM_00400 6.3e-134 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KLIOFDBM_00401 9.3e-21 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KLIOFDBM_00402 7.6e-117 yceD S Uncharacterized ACR, COG1399
KLIOFDBM_00403 6.3e-76
KLIOFDBM_00404 4.3e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLIOFDBM_00405 1.4e-47 S Protein of unknown function (DUF3039)
KLIOFDBM_00406 1.9e-197 yghZ C Aldo/keto reductase family
KLIOFDBM_00407 6.3e-78 soxR K MerR, DNA binding
KLIOFDBM_00408 4.5e-117
KLIOFDBM_00409 1.5e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLIOFDBM_00410 7e-144 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KLIOFDBM_00411 6.6e-126 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLIOFDBM_00412 2.4e-176 S Auxin Efflux Carrier
KLIOFDBM_00415 0.0 pgi 5.3.1.9 G Belongs to the GPI family
KLIOFDBM_00416 5.3e-259 abcT3 P ATPases associated with a variety of cellular activities
KLIOFDBM_00417 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00418 1.5e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KLIOFDBM_00419 7.2e-164 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KLIOFDBM_00420 1e-159 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLIOFDBM_00421 3.6e-210 K helix_turn _helix lactose operon repressor
KLIOFDBM_00422 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KLIOFDBM_00423 3.6e-55 araE EGP Major facilitator Superfamily
KLIOFDBM_00426 0.0 cydD V ABC transporter transmembrane region
KLIOFDBM_00427 5.2e-38 EGP Major facilitator Superfamily
KLIOFDBM_00428 7.1e-261 G Bacterial extracellular solute-binding protein
KLIOFDBM_00429 1.1e-102 malC G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00430 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KLIOFDBM_00431 3.6e-191 K helix_turn _helix lactose operon repressor
KLIOFDBM_00432 1.6e-165 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
KLIOFDBM_00433 2.1e-140 L Protein of unknown function (DUF1524)
KLIOFDBM_00434 1.8e-150 S Domain of unknown function (DUF4143)
KLIOFDBM_00435 2.6e-231 mntH P H( )-stimulated, divalent metal cation uptake system
KLIOFDBM_00436 3.3e-281 EGP Major facilitator Superfamily
KLIOFDBM_00437 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
KLIOFDBM_00438 2.8e-310 rfbP 2.7.8.6 M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
KLIOFDBM_00439 5.7e-109 3.1.3.48 T Low molecular weight phosphatase family
KLIOFDBM_00440 1.3e-37 L Transposase and inactivated derivatives IS30 family
KLIOFDBM_00441 7.9e-101 cps1D M Domain of unknown function (DUF4422)
KLIOFDBM_00442 1.4e-223 glf 5.4.99.9 M UDP-galactopyranose mutase
KLIOFDBM_00443 1.2e-27 L Integrase core domain
KLIOFDBM_00444 6.1e-31 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLIOFDBM_00445 5e-84 L Transposase and inactivated derivatives IS30 family
KLIOFDBM_00446 6.5e-12 S Psort location Extracellular, score 8.82
KLIOFDBM_00448 8.1e-36 K Bacterial regulatory proteins, lacI family
KLIOFDBM_00449 2.6e-85 K Bacterial regulatory proteins, lacI family
KLIOFDBM_00450 1.1e-156 P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00451 1.1e-175 P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00452 4.4e-266 G Bacterial extracellular solute-binding protein
KLIOFDBM_00453 6.8e-245 4.2.1.68 M Enolase C-terminal domain-like
KLIOFDBM_00454 5.8e-146 IQ KR domain
KLIOFDBM_00455 4.1e-111 S Amidohydrolase
KLIOFDBM_00456 7.7e-163 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
KLIOFDBM_00457 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
KLIOFDBM_00458 2.2e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
KLIOFDBM_00459 1.1e-53 acyP 3.6.1.7 C Acylphosphatase
KLIOFDBM_00460 1.1e-253 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KLIOFDBM_00461 1.8e-220 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KLIOFDBM_00462 2.7e-111 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
KLIOFDBM_00463 2.3e-99
KLIOFDBM_00464 3.4e-120 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KLIOFDBM_00465 8.3e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
KLIOFDBM_00466 1.6e-279 S Uncharacterized protein conserved in bacteria (DUF2252)
KLIOFDBM_00467 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
KLIOFDBM_00468 1.9e-217 EGP Major facilitator Superfamily
KLIOFDBM_00469 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
KLIOFDBM_00470 3.4e-123 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
KLIOFDBM_00471 6.9e-273 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KLIOFDBM_00472 1.5e-175 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
KLIOFDBM_00473 4.1e-162 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLIOFDBM_00474 8.4e-128 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLIOFDBM_00475 7.4e-46 M Lysin motif
KLIOFDBM_00476 8.4e-78 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLIOFDBM_00477 7.5e-230 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KLIOFDBM_00478 0.0 L DNA helicase
KLIOFDBM_00479 1.3e-93 mraZ K Belongs to the MraZ family
KLIOFDBM_00480 1.8e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KLIOFDBM_00481 1.3e-65 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KLIOFDBM_00482 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
KLIOFDBM_00483 2.6e-155 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLIOFDBM_00484 2e-240 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KLIOFDBM_00485 1.7e-204 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLIOFDBM_00486 4.3e-272 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KLIOFDBM_00487 1.5e-225 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
KLIOFDBM_00488 1.1e-217 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLIOFDBM_00489 7.5e-283 murC 6.3.2.8 M Belongs to the MurCDEF family
KLIOFDBM_00490 8.1e-172 ftsQ 6.3.2.4 D Cell division protein FtsQ
KLIOFDBM_00491 7e-15
KLIOFDBM_00492 9.5e-44 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLIOFDBM_00493 2.3e-167 2.7.1.4 G pfkB family carbohydrate kinase
KLIOFDBM_00494 5e-221 GK ROK family
KLIOFDBM_00495 2.2e-165 2.7.1.2 GK ROK family
KLIOFDBM_00496 1.5e-208 GK ROK family
KLIOFDBM_00497 1.8e-150 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLIOFDBM_00498 6.1e-246 nagA 3.5.1.25 G Amidohydrolase family
KLIOFDBM_00499 3.1e-95 3.6.1.55 F NUDIX domain
KLIOFDBM_00500 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
KLIOFDBM_00501 3.4e-302 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
KLIOFDBM_00502 0.0 smc D Required for chromosome condensation and partitioning
KLIOFDBM_00503 1.1e-44 V Acetyltransferase (GNAT) domain
KLIOFDBM_00504 6.9e-192 V Acetyltransferase (GNAT) domain
KLIOFDBM_00505 5.2e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLIOFDBM_00506 1.4e-30 entF 6.3.2.14 Q Activates the carboxylate group of L-serine via ATP- dependent PPi exchange reactions to the aminoacyladenylate, preparing that molecule for the final stages of enterobactin synthesis. Holo-EntF acts as the catalyst for the formation of the three amide and three ester bonds present in the cyclic (2,3- dihydroxybenzoyl)serine trimer enterobactin, using seryladenylate and acyl-holo-EntB (acylated with 2,3-dihydroxybenzoate by EntE)
KLIOFDBM_00507 3.2e-34 mdtJ P Catalyzes the excretion of spermidine
KLIOFDBM_00508 8.7e-24 rhtB E Conducts the efflux of homoserine and homoserine lactone
KLIOFDBM_00509 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
KLIOFDBM_00510 8e-174 3.4.22.70 M Sortase family
KLIOFDBM_00511 0.0 M domain protein
KLIOFDBM_00512 0.0 M cell wall anchor domain protein
KLIOFDBM_00513 1.5e-186 K Psort location Cytoplasmic, score
KLIOFDBM_00514 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
KLIOFDBM_00515 3.7e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KLIOFDBM_00516 2.4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KLIOFDBM_00517 1.8e-251 yhjE EGP Sugar (and other) transporter
KLIOFDBM_00518 3.7e-180 K helix_turn _helix lactose operon repressor
KLIOFDBM_00519 1.7e-277 scrT G Transporter major facilitator family protein
KLIOFDBM_00520 4.1e-297 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
KLIOFDBM_00521 6e-202 K helix_turn _helix lactose operon repressor
KLIOFDBM_00522 7.2e-51 natB E Receptor family ligand binding region
KLIOFDBM_00523 8.7e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLIOFDBM_00524 4.4e-141 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLIOFDBM_00525 4.5e-280 clcA P Voltage gated chloride channel
KLIOFDBM_00526 2e-244 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLIOFDBM_00527 2.4e-195 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
KLIOFDBM_00528 1.2e-166 yicL EG EamA-like transporter family
KLIOFDBM_00530 9.9e-169 htpX O Belongs to the peptidase M48B family
KLIOFDBM_00531 1e-276 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
KLIOFDBM_00532 0.0 cadA P E1-E2 ATPase
KLIOFDBM_00533 1.4e-228 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
KLIOFDBM_00534 1e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KLIOFDBM_00536 8.3e-146 yplQ S Haemolysin-III related
KLIOFDBM_00537 3.7e-88 yjcF Q Acetyltransferase (GNAT) domain
KLIOFDBM_00538 3.5e-52 ybjQ S Putative heavy-metal-binding
KLIOFDBM_00539 3.4e-166 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KLIOFDBM_00540 3e-125 S Domain of unknown function (DUF4928)
KLIOFDBM_00541 1.2e-173 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
KLIOFDBM_00542 2.1e-259 L Z1 domain
KLIOFDBM_00543 3.4e-32 S Putative PD-(D/E)XK family member, (DUF4420)
KLIOFDBM_00544 1e-32 S Putative PD-(D/E)XK family member, (DUF4420)
KLIOFDBM_00545 2.3e-241 S AIPR protein
KLIOFDBM_00546 1e-175 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
KLIOFDBM_00547 8.3e-164 M Glycosyltransferase like family 2
KLIOFDBM_00548 8.8e-198 S Fic/DOC family
KLIOFDBM_00549 1.1e-130 S Pyridoxamine 5'-phosphate oxidase
KLIOFDBM_00550 6.9e-200 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLIOFDBM_00551 0.0 lysX S Uncharacterised conserved protein (DUF2156)
KLIOFDBM_00552 4.3e-253 S Putative esterase
KLIOFDBM_00553 7.1e-20
KLIOFDBM_00554 7.2e-170 yddG EG EamA-like transporter family
KLIOFDBM_00555 3.4e-91 hsp20 O Hsp20/alpha crystallin family
KLIOFDBM_00556 2.9e-212 pldB 3.1.1.5 I Serine aminopeptidase, S33
KLIOFDBM_00557 1.7e-142 3.5.2.10 S Creatinine amidohydrolase
KLIOFDBM_00558 0.0 3.1.3.5 F 5'-nucleotidase, C-terminal domain
KLIOFDBM_00559 1.2e-210 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
KLIOFDBM_00560 4.3e-253 hisS 6.1.1.21 J Histidyl-tRNA synthetase
KLIOFDBM_00561 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KLIOFDBM_00562 5.2e-101 S Aminoacyl-tRNA editing domain
KLIOFDBM_00563 7.6e-152 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
KLIOFDBM_00564 1.1e-144 gluB ET Belongs to the bacterial solute-binding protein 3 family
KLIOFDBM_00565 3.4e-110 gluC E Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00566 1.2e-194 gluD E Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00567 9.9e-291 phoN I PAP2 superfamily
KLIOFDBM_00568 5.1e-111 argO S LysE type translocator
KLIOFDBM_00569 3.5e-285 ydfD EK Alanine-glyoxylate amino-transferase
KLIOFDBM_00570 1.5e-197 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
KLIOFDBM_00571 0.0 helY L DEAD DEAH box helicase
KLIOFDBM_00572 7.5e-250 rarA L Recombination factor protein RarA
KLIOFDBM_00573 6.9e-11 KT Transcriptional regulatory protein, C terminal
KLIOFDBM_00574 2.1e-34 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KLIOFDBM_00575 5.5e-251 EGP Major facilitator Superfamily
KLIOFDBM_00576 3.8e-187 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KLIOFDBM_00577 6.9e-52
KLIOFDBM_00578 1.6e-53 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KLIOFDBM_00579 3.1e-47 yhbY J CRS1_YhbY
KLIOFDBM_00580 0.0 ecfA GP ABC transporter, ATP-binding protein
KLIOFDBM_00581 1.3e-93 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KLIOFDBM_00582 6.4e-198 S Glycosyltransferase, group 2 family protein
KLIOFDBM_00583 2.5e-149 C Putative TM nitroreductase
KLIOFDBM_00584 3.2e-141 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
KLIOFDBM_00585 3e-303 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
KLIOFDBM_00586 6.2e-241 lacY P LacY proton/sugar symporter
KLIOFDBM_00587 1.8e-195 K helix_turn _helix lactose operon repressor
KLIOFDBM_00588 6.6e-257 O SERine Proteinase INhibitors
KLIOFDBM_00589 1.3e-190
KLIOFDBM_00590 6.1e-123 K helix_turn_helix, Lux Regulon
KLIOFDBM_00591 8.3e-215 2.7.13.3 T Histidine kinase
KLIOFDBM_00592 7.1e-248 ydjK G Sugar (and other) transporter
KLIOFDBM_00593 4.7e-61 S Thiamine-binding protein
KLIOFDBM_00594 1e-140 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLIOFDBM_00595 1.6e-227 O AAA domain (Cdc48 subfamily)
KLIOFDBM_00596 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KLIOFDBM_00597 1e-157 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KLIOFDBM_00598 3.3e-296 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KLIOFDBM_00599 2.8e-248 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLIOFDBM_00600 1.2e-211 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KLIOFDBM_00601 6.6e-68 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KLIOFDBM_00602 4.9e-45 yggT S YGGT family
KLIOFDBM_00603 4.9e-20 tccB2 V DivIVA protein
KLIOFDBM_00604 1.6e-89 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KLIOFDBM_00605 9e-178 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KLIOFDBM_00606 2.4e-200 K WYL domain
KLIOFDBM_00607 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
KLIOFDBM_00608 5.3e-68 yneG S Domain of unknown function (DUF4186)
KLIOFDBM_00609 1e-167 dkgA 1.1.1.346 C Aldo/keto reductase family
KLIOFDBM_00610 0.0 4.2.1.53 S MCRA family
KLIOFDBM_00611 1.1e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLIOFDBM_00612 4.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KLIOFDBM_00613 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
KLIOFDBM_00614 1.2e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLIOFDBM_00615 4.3e-132 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KLIOFDBM_00616 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLIOFDBM_00617 1.4e-117 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
KLIOFDBM_00618 2.5e-124 apl 3.1.3.1 S SNARE associated Golgi protein
KLIOFDBM_00619 2.6e-286 arc O AAA ATPase forming ring-shaped complexes
KLIOFDBM_00620 1.8e-133 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KLIOFDBM_00621 5.8e-280 manR K PRD domain
KLIOFDBM_00622 2.6e-71 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KLIOFDBM_00623 4e-78 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KLIOFDBM_00624 2.1e-46 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
KLIOFDBM_00625 4.8e-162 G Phosphotransferase System
KLIOFDBM_00626 6.1e-134 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
KLIOFDBM_00627 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
KLIOFDBM_00628 8.9e-175 hisN 3.1.3.25 G Inositol monophosphatase family
KLIOFDBM_00630 1.5e-283 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KLIOFDBM_00631 8.1e-42 hup L Belongs to the bacterial histone-like protein family
KLIOFDBM_00632 0.0 S Lysylphosphatidylglycerol synthase TM region
KLIOFDBM_00633 2.7e-277 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
KLIOFDBM_00634 2.9e-111 ykoE S ABC-type cobalt transport system, permease component
KLIOFDBM_00635 4.4e-254 S PGAP1-like protein
KLIOFDBM_00636 3.1e-56
KLIOFDBM_00637 2.5e-152 S von Willebrand factor (vWF) type A domain
KLIOFDBM_00638 8.8e-190 S von Willebrand factor (vWF) type A domain
KLIOFDBM_00639 2.6e-84
KLIOFDBM_00640 1.3e-163 S Protein of unknown function DUF58
KLIOFDBM_00641 1.4e-187 moxR S ATPase family associated with various cellular activities (AAA)
KLIOFDBM_00642 1.9e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLIOFDBM_00643 3.1e-84 S LytR cell envelope-related transcriptional attenuator
KLIOFDBM_00644 6.1e-38 K 'Cold-shock' DNA-binding domain
KLIOFDBM_00645 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLIOFDBM_00646 4.2e-33 S Proteins of 100 residues with WXG
KLIOFDBM_00647 5.1e-100
KLIOFDBM_00648 4.4e-132 KT Response regulator receiver domain protein
KLIOFDBM_00649 1.6e-309 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KLIOFDBM_00650 1.7e-66 cspB K 'Cold-shock' DNA-binding domain
KLIOFDBM_00651 9e-179 S Protein of unknown function (DUF3027)
KLIOFDBM_00652 5.4e-178 uspA T Belongs to the universal stress protein A family
KLIOFDBM_00653 0.0 clpC O ATPase family associated with various cellular activities (AAA)
KLIOFDBM_00654 5.7e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
KLIOFDBM_00655 1.4e-281 purR QT Purine catabolism regulatory protein-like family
KLIOFDBM_00656 4e-251 proP EGP Sugar (and other) transporter
KLIOFDBM_00657 6.6e-39 L Psort location Cytoplasmic, score 8.87
KLIOFDBM_00658 3.4e-50 S Appr-1'-p processing enzyme
KLIOFDBM_00659 7.1e-86 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLIOFDBM_00660 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
KLIOFDBM_00661 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
KLIOFDBM_00662 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
KLIOFDBM_00663 3e-245 srrA1 G Bacterial extracellular solute-binding protein
KLIOFDBM_00664 4.3e-172 malC G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00665 6.7e-156 lacG G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_00666 1.9e-263 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
KLIOFDBM_00667 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KLIOFDBM_00668 0.0 3.2.1.96 G Glycosyl hydrolase family 85
KLIOFDBM_00669 6e-205 K helix_turn _helix lactose operon repressor
KLIOFDBM_00670 6.1e-243 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KLIOFDBM_00671 1.7e-256 S Metal-independent alpha-mannosidase (GH125)
KLIOFDBM_00672 1.1e-31
KLIOFDBM_00673 2.6e-129 C Putative TM nitroreductase
KLIOFDBM_00674 4.9e-168 EG EamA-like transporter family
KLIOFDBM_00675 2e-70 pdxH S Pfam:Pyridox_oxidase
KLIOFDBM_00676 2.9e-232 L ribosomal rna small subunit methyltransferase
KLIOFDBM_00677 5.4e-166 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KLIOFDBM_00678 5.3e-170 corA P CorA-like Mg2+ transporter protein
KLIOFDBM_00679 2.3e-159 ET Bacterial periplasmic substrate-binding proteins
KLIOFDBM_00680 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLIOFDBM_00681 4.9e-81 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
KLIOFDBM_00682 2.6e-308 comE S Competence protein
KLIOFDBM_00683 9e-173 holA 2.7.7.7 L DNA polymerase III delta subunit
KLIOFDBM_00684 2.6e-87 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
KLIOFDBM_00685 1.9e-158 yeaZ 2.3.1.234 O Glycoprotease family
KLIOFDBM_00686 1.4e-104 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
KLIOFDBM_00687 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLIOFDBM_00689 0.0 V FtsX-like permease family
KLIOFDBM_00690 3.3e-124 V ABC transporter
KLIOFDBM_00691 7.7e-109 K Bacterial regulatory proteins, tetR family
KLIOFDBM_00692 1e-136 L PFAM Relaxase mobilization nuclease family protein
KLIOFDBM_00693 5.1e-142 S Fic/DOC family
KLIOFDBM_00698 9e-87 2.7.11.1 S HipA-like C-terminal domain
KLIOFDBM_00699 3.7e-18 L Belongs to the 'phage' integrase family
KLIOFDBM_00700 1.6e-28 uup S ABC transporter, ATP-binding protein
KLIOFDBM_00701 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
KLIOFDBM_00702 2e-129 fhaA T Protein of unknown function (DUF2662)
KLIOFDBM_00703 1e-74 fhaB T Inner membrane component of T3SS, cytoplasmic domain
KLIOFDBM_00704 1.8e-271 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
KLIOFDBM_00705 1e-277 rodA D Belongs to the SEDS family
KLIOFDBM_00706 4.5e-261 pbpA M penicillin-binding protein
KLIOFDBM_00707 1.3e-171 T Protein tyrosine kinase
KLIOFDBM_00708 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
KLIOFDBM_00709 2.9e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
KLIOFDBM_00710 3.8e-229 srtA 3.4.22.70 M Sortase family
KLIOFDBM_00711 1.8e-118 S Bacterial protein of unknown function (DUF881)
KLIOFDBM_00712 7.5e-69 crgA D Involved in cell division
KLIOFDBM_00713 3e-120 gluP 3.4.21.105 S Rhomboid family
KLIOFDBM_00714 4.5e-35
KLIOFDBM_00715 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KLIOFDBM_00716 3.7e-72 I Sterol carrier protein
KLIOFDBM_00717 2.5e-224 EGP Major Facilitator Superfamily
KLIOFDBM_00718 3.2e-209 2.7.13.3 T Histidine kinase
KLIOFDBM_00719 5.5e-113 K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KLIOFDBM_00720 1.2e-38 S Protein of unknown function (DUF3073)
KLIOFDBM_00721 5.5e-203 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLIOFDBM_00722 3.3e-289 S Amidohydrolase family
KLIOFDBM_00723 9.2e-157 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KLIOFDBM_00724 4e-44 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KLIOFDBM_00725 0.0 yjjP S Threonine/Serine exporter, ThrE
KLIOFDBM_00726 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KLIOFDBM_00727 1.9e-308 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KLIOFDBM_00728 2.5e-92 S AAA domain
KLIOFDBM_00729 0.0 yliE T Putative diguanylate phosphodiesterase
KLIOFDBM_00730 2.3e-108 S Domain of unknown function (DUF4956)
KLIOFDBM_00731 7.4e-152 P VTC domain
KLIOFDBM_00732 3.1e-304 cotH M CotH kinase protein
KLIOFDBM_00733 2.1e-272 pelG S Putative exopolysaccharide Exporter (EPS-E)
KLIOFDBM_00734 4.5e-252 pelF GT4 M Domain of unknown function (DUF3492)
KLIOFDBM_00735 1.3e-14 pelF GT4 M Domain of unknown function (DUF3492)
KLIOFDBM_00736 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
KLIOFDBM_00737 5.7e-161
KLIOFDBM_00738 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
KLIOFDBM_00739 1.6e-127
KLIOFDBM_00740 8.5e-100
KLIOFDBM_00741 1.5e-19 S Psort location CytoplasmicMembrane, score
KLIOFDBM_00742 8e-94 rpoE4 K Sigma-70 region 2
KLIOFDBM_00743 4.6e-26 2.7.13.3 T Histidine kinase
KLIOFDBM_00744 1.4e-49 S Bacterial toxin of type II toxin-antitoxin system, YafQ
KLIOFDBM_00745 2.1e-39 relB L RelB antitoxin
KLIOFDBM_00746 2.5e-43 V MacB-like periplasmic core domain
KLIOFDBM_00747 3.3e-100 S Acetyltransferase (GNAT) domain
KLIOFDBM_00748 4.5e-25 S Uncharacterized protein conserved in bacteria (DUF2316)
KLIOFDBM_00749 1.5e-35 cefD 5.1.1.17 E Aminotransferase class-V
KLIOFDBM_00750 4e-14 cefD 5.1.1.17 E Aminotransferase, class V
KLIOFDBM_00751 3.5e-188 V VanZ like family
KLIOFDBM_00753 2.6e-258 mmuP E amino acid
KLIOFDBM_00754 6.3e-154 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KLIOFDBM_00755 6.5e-133 S SOS response associated peptidase (SRAP)
KLIOFDBM_00756 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KLIOFDBM_00757 4.6e-160 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KLIOFDBM_00758 5.3e-186 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KLIOFDBM_00759 9.4e-113 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
KLIOFDBM_00760 9.9e-42 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
KLIOFDBM_00761 8.7e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
KLIOFDBM_00762 7.3e-104 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLIOFDBM_00763 3.9e-168 S Bacterial protein of unknown function (DUF881)
KLIOFDBM_00764 3.9e-35 sbp S Protein of unknown function (DUF1290)
KLIOFDBM_00765 2.2e-140 S Bacterial protein of unknown function (DUF881)
KLIOFDBM_00766 6.7e-75 garA T Inner membrane component of T3SS, cytoplasmic domain
KLIOFDBM_00767 1.1e-110 K helix_turn_helix, mercury resistance
KLIOFDBM_00768 1.5e-65
KLIOFDBM_00769 2.6e-35
KLIOFDBM_00770 1.1e-138 pgp 3.1.3.18 S HAD-hyrolase-like
KLIOFDBM_00771 5.1e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KLIOFDBM_00772 0.0 helY L DEAD DEAH box helicase
KLIOFDBM_00773 6.8e-53
KLIOFDBM_00774 0.0 pafB K WYL domain
KLIOFDBM_00775 2.5e-291 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
KLIOFDBM_00776 1.6e-162 supH S Sucrose-6F-phosphate phosphohydrolase
KLIOFDBM_00778 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
KLIOFDBM_00779 4.5e-143 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLIOFDBM_00780 4.7e-118 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KLIOFDBM_00781 4.1e-31
KLIOFDBM_00782 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KLIOFDBM_00783 4.7e-233
KLIOFDBM_00784 2.9e-165 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KLIOFDBM_00785 3.1e-223 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KLIOFDBM_00786 3e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLIOFDBM_00787 3.6e-52 yajC U Preprotein translocase subunit
KLIOFDBM_00788 2e-197 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KLIOFDBM_00789 2.7e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KLIOFDBM_00790 2.7e-100 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KLIOFDBM_00791 2e-111 yebC K transcriptional regulatory protein
KLIOFDBM_00792 1.2e-111 hit 2.7.7.53 FG HIT domain
KLIOFDBM_00793 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLIOFDBM_00799 2.2e-135 S PAC2 family
KLIOFDBM_00800 1.8e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KLIOFDBM_00801 9.6e-157 G Fructosamine kinase
KLIOFDBM_00802 6.8e-212 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KLIOFDBM_00803 3.7e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KLIOFDBM_00804 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
KLIOFDBM_00805 3.6e-202 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KLIOFDBM_00806 3.3e-234 brnQ U Component of the transport system for branched-chain amino acids
KLIOFDBM_00807 2.5e-185
KLIOFDBM_00808 1.2e-299 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
KLIOFDBM_00809 4.9e-159 S Sucrose-6F-phosphate phosphohydrolase
KLIOFDBM_00810 2.5e-175 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLIOFDBM_00811 2.7e-33 secG U Preprotein translocase SecG subunit
KLIOFDBM_00812 6e-146 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLIOFDBM_00813 1e-218 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
KLIOFDBM_00814 3.5e-169 whiA K May be required for sporulation
KLIOFDBM_00815 1.1e-178 rapZ S Displays ATPase and GTPase activities
KLIOFDBM_00816 6.2e-190 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
KLIOFDBM_00817 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KLIOFDBM_00818 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KLIOFDBM_00819 5.5e-233 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
KLIOFDBM_00820 1.1e-89 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
KLIOFDBM_00821 6.1e-21 G ATPases associated with a variety of cellular activities
KLIOFDBM_00822 1.2e-129 S Enoyl-(Acyl carrier protein) reductase
KLIOFDBM_00823 6.4e-301 ybiT S ABC transporter
KLIOFDBM_00824 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KLIOFDBM_00825 9.4e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KLIOFDBM_00826 9.4e-172 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
KLIOFDBM_00827 2.4e-217 MA20_36090 S Psort location Cytoplasmic, score 8.87
KLIOFDBM_00828 9e-29
KLIOFDBM_00829 5e-125 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLIOFDBM_00830 4e-181 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KLIOFDBM_00831 6.9e-158 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KLIOFDBM_00832 2.7e-174 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
KLIOFDBM_00833 9.1e-289 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KLIOFDBM_00834 7e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KLIOFDBM_00835 1.6e-177 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KLIOFDBM_00836 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KLIOFDBM_00837 4.8e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KLIOFDBM_00838 1.6e-162 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
KLIOFDBM_00839 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KLIOFDBM_00841 5.8e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
KLIOFDBM_00842 9.4e-200 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KLIOFDBM_00843 1.3e-133 S Phospholipase/Carboxylesterase
KLIOFDBM_00845 2e-140 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KLIOFDBM_00846 9.3e-146 S phosphoesterase or phosphohydrolase
KLIOFDBM_00847 5e-90 S Appr-1'-p processing enzyme
KLIOFDBM_00848 1.5e-177 I alpha/beta hydrolase fold
KLIOFDBM_00849 4.4e-25
KLIOFDBM_00851 2.2e-82 L Transposase, Mutator family
KLIOFDBM_00852 1.2e-141
KLIOFDBM_00853 3.6e-94 bcp 1.11.1.15 O Redoxin
KLIOFDBM_00854 1e-156 S Sucrose-6F-phosphate phosphohydrolase
KLIOFDBM_00855 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
KLIOFDBM_00856 7.3e-244 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
KLIOFDBM_00857 8.6e-81
KLIOFDBM_00858 0.0 S Glycosyl hydrolases related to GH101 family, GH129
KLIOFDBM_00859 0.0 E ABC transporter, substrate-binding protein, family 5
KLIOFDBM_00860 5.4e-44
KLIOFDBM_00862 1.4e-305 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KLIOFDBM_00863 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
KLIOFDBM_00864 1.2e-191 K helix_turn _helix lactose operon repressor
KLIOFDBM_00866 4.1e-253 hemN H Involved in the biosynthesis of porphyrin-containing compound
KLIOFDBM_00867 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KLIOFDBM_00868 5.8e-34 rpsT J Binds directly to 16S ribosomal RNA
KLIOFDBM_00869 8.8e-139 S UPF0126 domain
KLIOFDBM_00870 2.2e-141 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
KLIOFDBM_00871 1.6e-226 ilvE 2.6.1.42 E Amino-transferase class IV
KLIOFDBM_00872 2.7e-93 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KLIOFDBM_00873 9.2e-234 yhjX EGP Major facilitator Superfamily
KLIOFDBM_00874 3.3e-232 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KLIOFDBM_00875 3e-42 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
KLIOFDBM_00876 9e-204 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
KLIOFDBM_00877 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KLIOFDBM_00878 2.8e-185 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KLIOFDBM_00879 4.3e-248 corC S CBS domain
KLIOFDBM_00880 4.7e-102 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLIOFDBM_00881 2.7e-216 phoH T PhoH-like protein
KLIOFDBM_00882 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
KLIOFDBM_00883 6.8e-148 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KLIOFDBM_00885 3.3e-166 spoU 2.1.1.185 J SpoU rRNA Methylase family
KLIOFDBM_00886 4.4e-241 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KLIOFDBM_00887 3.2e-109 yitW S Iron-sulfur cluster assembly protein
KLIOFDBM_00888 4e-101 iscU C SUF system FeS assembly protein, NifU family
KLIOFDBM_00889 5.5e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLIOFDBM_00890 7e-144 sufC O FeS assembly ATPase SufC
KLIOFDBM_00891 7.3e-236 sufD O FeS assembly protein SufD
KLIOFDBM_00892 1.5e-291 sufB O FeS assembly protein SufB
KLIOFDBM_00893 4.5e-311 S L,D-transpeptidase catalytic domain
KLIOFDBM_00894 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KLIOFDBM_00895 1.3e-94 K Psort location Cytoplasmic, score
KLIOFDBM_00896 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KLIOFDBM_00897 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KLIOFDBM_00898 4.7e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KLIOFDBM_00899 1.8e-70 3.4.23.43 S Type IV leader peptidase family
KLIOFDBM_00900 1.1e-193 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KLIOFDBM_00901 2.7e-71 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLIOFDBM_00902 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLIOFDBM_00903 1.6e-35
KLIOFDBM_00904 2.3e-55 WQ51_05790 S Bacterial protein of unknown function (DUF948)
KLIOFDBM_00905 1.9e-129 pgm3 G Phosphoglycerate mutase family
KLIOFDBM_00906 1.2e-48 relB L RelB antitoxin
KLIOFDBM_00907 3e-65 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KLIOFDBM_00908 1.2e-111 E Transglutaminase-like superfamily
KLIOFDBM_00909 1.5e-45 sdpI S SdpI/YhfL protein family
KLIOFDBM_00910 5.7e-70 3.5.4.5 F cytidine deaminase activity
KLIOFDBM_00911 1.3e-150 S Peptidase C26
KLIOFDBM_00912 1.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLIOFDBM_00913 4.1e-151 lolD V ABC transporter
KLIOFDBM_00914 8.2e-216 V FtsX-like permease family
KLIOFDBM_00915 6.9e-63 S Domain of unknown function (DUF4418)
KLIOFDBM_00916 0.0 pcrA 3.6.4.12 L DNA helicase
KLIOFDBM_00917 1.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KLIOFDBM_00918 3.7e-241 pbuX F Permease family
KLIOFDBM_00919 3.4e-45 S Protein of unknown function (DUF2975)
KLIOFDBM_00920 1.1e-152 I Serine aminopeptidase, S33
KLIOFDBM_00921 3.1e-162 M pfam nlp p60
KLIOFDBM_00922 1e-105 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
KLIOFDBM_00923 1.1e-110 3.4.13.21 E Peptidase family S51
KLIOFDBM_00924 1.9e-196
KLIOFDBM_00925 2e-47 E lipolytic protein G-D-S-L family
KLIOFDBM_00926 1e-281 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KLIOFDBM_00927 3.6e-226 V ABC-2 family transporter protein
KLIOFDBM_00928 3.3e-220 V ABC-2 family transporter protein
KLIOFDBM_00929 5.1e-176 V ATPases associated with a variety of cellular activities
KLIOFDBM_00930 1.8e-10 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
KLIOFDBM_00931 1.1e-216 T Histidine kinase
KLIOFDBM_00932 1.8e-113 K helix_turn_helix, Lux Regulon
KLIOFDBM_00933 4.3e-112 MA20_27875 P Protein of unknown function DUF47
KLIOFDBM_00934 2.8e-188 pit P Phosphate transporter family
KLIOFDBM_00935 6.2e-254 nplT G Alpha amylase, catalytic domain
KLIOFDBM_00936 1.8e-308 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
KLIOFDBM_00937 4.2e-234 rutG F Permease family
KLIOFDBM_00938 1.4e-161 3.1.3.73 G Phosphoglycerate mutase family
KLIOFDBM_00939 1.5e-106 3.1.3.27 E haloacid dehalogenase-like hydrolase
KLIOFDBM_00940 6.2e-236 EGP Major facilitator Superfamily
KLIOFDBM_00942 1.4e-62 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLIOFDBM_00943 8.3e-131 S Sulfite exporter TauE/SafE
KLIOFDBM_00944 2.4e-14 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KLIOFDBM_00945 1.1e-43 K Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KLIOFDBM_00946 6e-99 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
KLIOFDBM_00947 5.6e-54 sdpI S SdpI/YhfL protein family
KLIOFDBM_00948 1.5e-67 2.7.13.3 T Histidine kinase
KLIOFDBM_00949 9.2e-95 K helix_turn_helix, Lux Regulon
KLIOFDBM_00950 3.5e-90 ydaF_1 J Acetyltransferase (GNAT) domain
KLIOFDBM_00951 1.2e-46 S Protein of unknown function (DUF2089)
KLIOFDBM_00952 2.6e-37
KLIOFDBM_00953 4.3e-129 S EamA-like transporter family
KLIOFDBM_00954 1.8e-102
KLIOFDBM_00955 4.6e-129
KLIOFDBM_00956 6.4e-122 V ATPases associated with a variety of cellular activities
KLIOFDBM_00957 2.5e-15 fic D Fic/DOC family
KLIOFDBM_00958 1.5e-22
KLIOFDBM_00959 5.4e-93
KLIOFDBM_00960 3e-31 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KLIOFDBM_00961 2.9e-116 XK27_07525 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
KLIOFDBM_00962 3.1e-92 yidC U Membrane protein insertase, YidC Oxa1 family
KLIOFDBM_00963 1.4e-41 2.6.1.76 EGP Major Facilitator Superfamily
KLIOFDBM_00964 6.3e-20 G Major facilitator Superfamily
KLIOFDBM_00965 2.3e-295 mmuP E amino acid
KLIOFDBM_00967 1.9e-64 yeaO K Protein of unknown function, DUF488
KLIOFDBM_00968 2.7e-73
KLIOFDBM_00969 6.5e-158 3.6.4.12
KLIOFDBM_00970 1.1e-91 yijF S Domain of unknown function (DUF1287)
KLIOFDBM_00971 5.4e-297 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KLIOFDBM_00972 1.5e-70 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KLIOFDBM_00973 3.9e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KLIOFDBM_00974 7.9e-16 3.5.1.124 S DJ-1/PfpI family
KLIOFDBM_00975 1.2e-52 3.5.1.124 S DJ-1/PfpI family
KLIOFDBM_00976 5.1e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KLIOFDBM_00977 2.4e-173 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
KLIOFDBM_00978 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KLIOFDBM_00979 6.3e-134 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KLIOFDBM_00980 8.5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLIOFDBM_00981 4.1e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
KLIOFDBM_00982 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLIOFDBM_00983 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
KLIOFDBM_00984 3.3e-91
KLIOFDBM_00985 3.8e-207 guaB 1.1.1.205 F IMP dehydrogenase family protein
KLIOFDBM_00986 6.7e-242 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
KLIOFDBM_00987 2.3e-256 G ABC transporter substrate-binding protein
KLIOFDBM_00988 1.3e-93 M Peptidase family M23
KLIOFDBM_00989 2.9e-84 L Phage integrase family
KLIOFDBM_00990 1.4e-69 L Phage integrase family
KLIOFDBM_00992 1.3e-224
KLIOFDBM_00993 3.8e-184 pstIR 2.1.1.72, 3.1.21.4 L BsuBI/PstI restriction endonuclease C-terminus
KLIOFDBM_00994 1.4e-267 hsdBM 2.1.1.72 L Eco57I restriction-modification methylase
KLIOFDBM_00995 0.0 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
KLIOFDBM_00996 6.6e-206 dcm 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KLIOFDBM_00997 0.0 topB 5.99.1.2 L DNA topoisomerase
KLIOFDBM_00999 2.3e-24 xerH L Phage integrase family
KLIOFDBM_01000 8.1e-39 M Bacterial capsule synthesis protein PGA_cap
KLIOFDBM_01001 1.7e-15 M Bacterial capsule synthesis protein PGA_cap
KLIOFDBM_01002 5e-182 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLIOFDBM_01003 1.1e-110 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
KLIOFDBM_01004 8.4e-117
KLIOFDBM_01005 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
KLIOFDBM_01006 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLIOFDBM_01007 3.7e-82 rpsI J Belongs to the universal ribosomal protein uS9 family
KLIOFDBM_01008 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KLIOFDBM_01009 2.3e-179 tdh 1.1.1.14 C Zinc-binding dehydrogenase
KLIOFDBM_01010 2.2e-233 EGP Major facilitator Superfamily
KLIOFDBM_01011 6e-75 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLIOFDBM_01012 1.6e-213 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KLIOFDBM_01013 2.7e-196 EGP Major facilitator Superfamily
KLIOFDBM_01014 2.2e-193 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
KLIOFDBM_01015 3.1e-170 rhaR_1 K helix_turn_helix, arabinose operon control protein
KLIOFDBM_01016 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLIOFDBM_01017 4.3e-145 ywiC S YwiC-like protein
KLIOFDBM_01018 8.2e-137 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KLIOFDBM_01019 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
KLIOFDBM_01020 8.7e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLIOFDBM_01021 3.1e-116 rplD J Forms part of the polypeptide exit tunnel
KLIOFDBM_01022 7.5e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KLIOFDBM_01023 1.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLIOFDBM_01024 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLIOFDBM_01025 5.7e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KLIOFDBM_01026 1.7e-100 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLIOFDBM_01027 2.2e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLIOFDBM_01028 4.1e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
KLIOFDBM_01029 6.4e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLIOFDBM_01030 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLIOFDBM_01031 1.3e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLIOFDBM_01032 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLIOFDBM_01033 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLIOFDBM_01034 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLIOFDBM_01035 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLIOFDBM_01036 2.4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KLIOFDBM_01037 6.7e-96 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLIOFDBM_01038 9.2e-26 rpmD J Ribosomal protein L30p/L7e
KLIOFDBM_01039 8.1e-76 rplO J binds to the 23S rRNA
KLIOFDBM_01040 1.4e-245 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KLIOFDBM_01041 1.1e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KLIOFDBM_01042 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLIOFDBM_01043 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KLIOFDBM_01044 9.5e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLIOFDBM_01045 1.5e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLIOFDBM_01046 3.4e-183 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLIOFDBM_01047 1.6e-62 rplQ J Ribosomal protein L17
KLIOFDBM_01048 5.7e-51 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
KLIOFDBM_01049 8.1e-31
KLIOFDBM_01050 4.1e-142
KLIOFDBM_01051 1.1e-65 S PrgI family protein
KLIOFDBM_01052 0.0 trsE U type IV secretory pathway VirB4
KLIOFDBM_01053 1e-258 isp2 3.2.1.96 M CHAP domain
KLIOFDBM_01054 2e-185
KLIOFDBM_01056 3.4e-65 S Putative amidase domain
KLIOFDBM_01057 1.5e-99 S Putative amidase domain
KLIOFDBM_01058 0.0 U Type IV secretory system Conjugative DNA transfer
KLIOFDBM_01059 6.6e-59
KLIOFDBM_01060 3.5e-46
KLIOFDBM_01061 9.9e-124
KLIOFDBM_01062 9.4e-259 ard S Antirestriction protein (ArdA)
KLIOFDBM_01063 7.1e-165
KLIOFDBM_01064 1.5e-161 S Protein of unknown function (DUF3801)
KLIOFDBM_01065 1.6e-271 rlx U Relaxase/Mobilisation nuclease domain
KLIOFDBM_01066 3.5e-70 S Bacterial mobilisation protein (MobC)
KLIOFDBM_01067 1.1e-84
KLIOFDBM_01068 1.3e-46
KLIOFDBM_01069 1.4e-265 K ParB-like nuclease domain
KLIOFDBM_01070 1.1e-107 S Domain of unknown function (DUF4192)
KLIOFDBM_01071 1.6e-233 T Histidine kinase
KLIOFDBM_01072 1.9e-124 K helix_turn_helix, Lux Regulon
KLIOFDBM_01073 1.9e-121 V ABC transporter
KLIOFDBM_01074 1.4e-17
KLIOFDBM_01075 4.1e-292 E Asparagine synthase
KLIOFDBM_01076 3.2e-35 E Asparagine synthase
KLIOFDBM_01077 2.7e-308 V ABC transporter transmembrane region
KLIOFDBM_01079 3.7e-164 spaB S Thiopeptide-type bacteriocin biosynthesis domain protein
KLIOFDBM_01080 5.4e-107 V Psort location Cytoplasmic, score
KLIOFDBM_01082 8.1e-116 V VanZ like family
KLIOFDBM_01083 5.3e-96 rpoE4 K Sigma-70 region 2
KLIOFDBM_01084 5.5e-22 S Psort location CytoplasmicMembrane, score
KLIOFDBM_01085 7.2e-42 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
KLIOFDBM_01087 4.4e-238 patB 4.4.1.8 E Aminotransferase, class I II
KLIOFDBM_01088 7.4e-221 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KLIOFDBM_01089 8.9e-167 fmt2 3.2.2.10 S Belongs to the LOG family
KLIOFDBM_01090 2.1e-112 safC S O-methyltransferase
KLIOFDBM_01091 2.7e-182 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
KLIOFDBM_01092 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
KLIOFDBM_01093 0.0 dprA 5.99.1.2 LU DNA recombination-mediator protein A
KLIOFDBM_01094 9.8e-291 comM O Magnesium chelatase, subunit ChlI C-terminal
KLIOFDBM_01095 8.3e-75 yraN L Belongs to the UPF0102 family
KLIOFDBM_01096 4.7e-23 L Transposase and inactivated derivatives IS30 family
KLIOFDBM_01097 2.8e-165 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KLIOFDBM_01098 4.5e-252 metY 2.5.1.49 E Aminotransferase class-V
KLIOFDBM_01099 1.7e-168 V ABC transporter, ATP-binding protein
KLIOFDBM_01100 0.0 MV MacB-like periplasmic core domain
KLIOFDBM_01101 1.1e-139 K helix_turn_helix, Lux Regulon
KLIOFDBM_01102 0.0 tcsS2 T Histidine kinase
KLIOFDBM_01103 1.2e-288 pip 3.4.11.5 S alpha/beta hydrolase fold
KLIOFDBM_01104 1.4e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLIOFDBM_01105 4.8e-154 cjaA ET Bacterial periplasmic substrate-binding proteins
KLIOFDBM_01106 1.2e-138 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
KLIOFDBM_01107 1.2e-118 E Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01108 7.4e-110 papP E Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01109 1.3e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KLIOFDBM_01110 6.9e-242 S HipA-like C-terminal domain
KLIOFDBM_01111 5.4e-17 K addiction module antidote protein HigA
KLIOFDBM_01112 3.5e-217 G Transmembrane secretion effector
KLIOFDBM_01113 1.6e-118 K Bacterial regulatory proteins, tetR family
KLIOFDBM_01114 1e-11
KLIOFDBM_01115 1e-42 cysB 4.2.1.22 EGP Major facilitator Superfamily
KLIOFDBM_01116 1.3e-25 cysB 4.2.1.22 EGP Major facilitator Superfamily
KLIOFDBM_01117 6.4e-31 L PFAM Integrase catalytic
KLIOFDBM_01118 1.8e-16 L Helix-turn-helix domain
KLIOFDBM_01119 1.2e-247 S Psort location CytoplasmicMembrane, score 9.99
KLIOFDBM_01120 1.1e-69
KLIOFDBM_01121 7.6e-237 wcoI DM Psort location CytoplasmicMembrane, score
KLIOFDBM_01122 5.1e-129
KLIOFDBM_01123 5e-171 S G5
KLIOFDBM_01124 3.3e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
KLIOFDBM_01125 9.3e-121 F Domain of unknown function (DUF4916)
KLIOFDBM_01126 1.3e-159 mhpC I Alpha/beta hydrolase family
KLIOFDBM_01127 1.3e-211 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
KLIOFDBM_01128 1.7e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KLIOFDBM_01129 1.6e-224 S Uncharacterized conserved protein (DUF2183)
KLIOFDBM_01130 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
KLIOFDBM_01131 2.7e-191 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KLIOFDBM_01132 4e-212 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
KLIOFDBM_01133 1.4e-130 glxR K helix_turn_helix, cAMP Regulatory protein
KLIOFDBM_01134 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KLIOFDBM_01135 1.8e-229 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
KLIOFDBM_01136 1.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KLIOFDBM_01137 6.3e-123 glpR K DeoR C terminal sensor domain
KLIOFDBM_01138 6.6e-253 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
KLIOFDBM_01139 1.3e-232 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
KLIOFDBM_01140 1.4e-15 lmrB EGP Major facilitator Superfamily
KLIOFDBM_01141 6.4e-44 gcvR T Belongs to the UPF0237 family
KLIOFDBM_01142 3.2e-253 S UPF0210 protein
KLIOFDBM_01143 3.7e-11 S Toxin Ldr, type I toxin-antitoxin system
KLIOFDBM_01144 3.2e-36 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KLIOFDBM_01145 2.1e-185 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
KLIOFDBM_01146 8.9e-90 K MarR family
KLIOFDBM_01147 0.0 V ABC transporter, ATP-binding protein
KLIOFDBM_01148 0.0 V ABC transporter transmembrane region
KLIOFDBM_01149 2.7e-135 rbsR K helix_turn _helix lactose operon repressor
KLIOFDBM_01150 6.8e-139 rihA_2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KLIOFDBM_01151 3.9e-169 EGP Major Facilitator Superfamily
KLIOFDBM_01152 1.1e-135 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLIOFDBM_01153 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLIOFDBM_01154 6.3e-61 L Transposase
KLIOFDBM_01155 0.0 cas3 L DEAD-like helicases superfamily
KLIOFDBM_01156 1.5e-137 cas5d S CRISPR-associated protein (Cas_Cas5)
KLIOFDBM_01157 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
KLIOFDBM_01158 8.7e-156 csd2 L CRISPR-associated protein Cas7
KLIOFDBM_01159 2.1e-131 cas4 3.1.12.1 L Domain of unknown function DUF83
KLIOFDBM_01160 4.2e-197 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLIOFDBM_01161 4.2e-49 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLIOFDBM_01164 4.7e-31 vapC S PIN domain
KLIOFDBM_01165 3.4e-14 kdgT U The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KLIOFDBM_01166 8.1e-138 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KLIOFDBM_01167 1.4e-192 opcA G Glucose-6-phosphate dehydrogenase subunit
KLIOFDBM_01168 5e-303 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLIOFDBM_01169 3.4e-290 3.5.2.6 V Beta-lactamase enzyme family
KLIOFDBM_01171 5.1e-300 pepD E Peptidase family C69
KLIOFDBM_01172 2.8e-196 XK27_01805 M Glycosyltransferase like family 2
KLIOFDBM_01173 1.4e-150 icaR K Bacterial regulatory proteins, tetR family
KLIOFDBM_01174 2.2e-171 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KLIOFDBM_01175 1e-227 amt U Ammonium Transporter Family
KLIOFDBM_01176 1e-54 glnB K Nitrogen regulatory protein P-II
KLIOFDBM_01177 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
KLIOFDBM_01178 1.3e-238 dinF V MatE
KLIOFDBM_01179 3.1e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KLIOFDBM_01180 1e-257 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
KLIOFDBM_01181 3.5e-140 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KLIOFDBM_01182 5.5e-38 S granule-associated protein
KLIOFDBM_01183 0.0 ubiB S ABC1 family
KLIOFDBM_01184 3.5e-71 K Periplasmic binding protein domain
KLIOFDBM_01185 1.2e-238 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
KLIOFDBM_01186 4.5e-155 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KLIOFDBM_01187 1.3e-187 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLIOFDBM_01188 2.2e-21 ulaR K Represses ulaG and the ulaABCDEF operon
KLIOFDBM_01189 2.1e-151 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
KLIOFDBM_01190 4.8e-45
KLIOFDBM_01191 1.1e-116 lacS G Psort location CytoplasmicMembrane, score 10.00
KLIOFDBM_01193 2e-120 V ATPases associated with a variety of cellular activities
KLIOFDBM_01194 2.2e-99
KLIOFDBM_01195 6.8e-81
KLIOFDBM_01196 3.2e-29 spaB S Lantibiotic dehydratase, C terminus
KLIOFDBM_01197 4.1e-18 V Lanthionine synthetase C-like protein
KLIOFDBM_01198 9.6e-41 V ATPase activity
KLIOFDBM_01199 4.9e-47 V ABC-2 type transporter
KLIOFDBM_01200 0.0 sprF 4.6.1.1 M Cell surface antigen C-terminus
KLIOFDBM_01202 7.8e-126 K Helix-turn-helix domain protein
KLIOFDBM_01203 2.1e-12
KLIOFDBM_01204 9.2e-71
KLIOFDBM_01205 1.7e-35
KLIOFDBM_01206 2.1e-103 parA D AAA domain
KLIOFDBM_01207 8e-83 S Transcription factor WhiB
KLIOFDBM_01208 7.4e-28 S Protein of unknown function (DUF3159)
KLIOFDBM_01209 4e-40 cysG 1.3.1.76, 2.1.1.107, 2.1.1.131, 3.7.1.12, 4.2.1.75, 4.99.1.3, 4.99.1.4 H Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KLIOFDBM_01210 2.6e-230 S AAA domain
KLIOFDBM_01211 3.1e-204 EGP Major Facilitator Superfamily
KLIOFDBM_01212 7.4e-31 L Transposase DDE domain
KLIOFDBM_01213 3.8e-12 L Transposase DDE domain
KLIOFDBM_01214 1.9e-105 K Bacterial regulatory proteins, tetR family
KLIOFDBM_01215 4.7e-257 MA20_36090 S Psort location Cytoplasmic, score 8.87
KLIOFDBM_01216 1.4e-89 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KLIOFDBM_01217 1.9e-81 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KLIOFDBM_01218 9.2e-72 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
KLIOFDBM_01219 2.8e-112 P Sodium/hydrogen exchanger family
KLIOFDBM_01221 4.9e-11
KLIOFDBM_01222 1.1e-97
KLIOFDBM_01223 0.0 1.3.98.1, 3.2.1.21 GH3 M Conserved repeat domain
KLIOFDBM_01224 2.1e-277 M LPXTG cell wall anchor motif
KLIOFDBM_01226 5.5e-86
KLIOFDBM_01227 1.6e-107
KLIOFDBM_01228 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLIOFDBM_01229 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KLIOFDBM_01230 1.1e-87 mtnE 2.6.1.83 E Aminotransferase class I and II
KLIOFDBM_01231 2.2e-218 M Glycosyl transferase 4-like domain
KLIOFDBM_01232 2.3e-195 ltaE 4.1.2.48 E Beta-eliminating lyase
KLIOFDBM_01234 6.6e-111 yocS S SBF-like CPA transporter family (DUF4137)
KLIOFDBM_01235 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLIOFDBM_01236 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KLIOFDBM_01237 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLIOFDBM_01238 6.2e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLIOFDBM_01239 1e-128 tmp1 S Domain of unknown function (DUF4391)
KLIOFDBM_01240 3e-145 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
KLIOFDBM_01241 1e-185 MA20_14895 S Conserved hypothetical protein 698
KLIOFDBM_01243 2.9e-30 S Psort location CytoplasmicMembrane, score
KLIOFDBM_01244 7.3e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLIOFDBM_01245 8.4e-88 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLIOFDBM_01246 1.8e-75 K MerR family regulatory protein
KLIOFDBM_01247 1.1e-197 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
KLIOFDBM_01248 1.1e-253 S Domain of unknown function (DUF4143)
KLIOFDBM_01249 7.9e-35
KLIOFDBM_01250 2.7e-77 KT Transcriptional regulatory protein, C terminal
KLIOFDBM_01251 7.1e-174 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
KLIOFDBM_01252 4.2e-147 E GDSL-like Lipase/Acylhydrolase family
KLIOFDBM_01253 1.1e-237 bglA 3.2.1.21 G Glycosyl hydrolase family 1
KLIOFDBM_01254 6.4e-299 E Bacterial extracellular solute-binding proteins, family 5 Middle
KLIOFDBM_01255 1.3e-174 EP Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01256 5.3e-155 EP Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01257 5e-141 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
KLIOFDBM_01258 2.7e-138 dppF E ABC transporter
KLIOFDBM_01259 0.0 3.2.1.25 G beta-mannosidase
KLIOFDBM_01260 9.2e-144 K helix_turn _helix lactose operon repressor
KLIOFDBM_01262 9.9e-217 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
KLIOFDBM_01263 7.3e-156 K LysR substrate binding domain
KLIOFDBM_01264 9.5e-216 EGP Major Facilitator Superfamily
KLIOFDBM_01265 3.8e-138 K LysR substrate binding domain
KLIOFDBM_01266 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KLIOFDBM_01267 5.7e-242 vbsD V MatE
KLIOFDBM_01268 5.1e-122 magIII L endonuclease III
KLIOFDBM_01270 5.7e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KLIOFDBM_01271 2.4e-40 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
KLIOFDBM_01272 1.6e-183 S Membrane transport protein
KLIOFDBM_01273 7.4e-48 4.1.1.44 L Cupin 2, conserved barrel domain protein
KLIOFDBM_01275 0.0 M probably involved in cell wall
KLIOFDBM_01276 9.1e-253 3.2.1.14 GH18 S Carbohydrate binding domain
KLIOFDBM_01277 0.0 T Diguanylate cyclase, GGDEF domain
KLIOFDBM_01278 7.1e-136 ybbM V Uncharacterised protein family (UPF0014)
KLIOFDBM_01279 1.4e-127 ybbL V ATPases associated with a variety of cellular activities
KLIOFDBM_01280 3.9e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLIOFDBM_01281 1.5e-92 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLIOFDBM_01282 2.2e-240 carA 6.3.5.5 F Belongs to the CarA family
KLIOFDBM_01283 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KLIOFDBM_01284 5.7e-169 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KLIOFDBM_01285 2.4e-104 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KLIOFDBM_01286 3.7e-136 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
KLIOFDBM_01288 0.0 tetP J Elongation factor G, domain IV
KLIOFDBM_01289 7.9e-126 ypfH S Phospholipase/Carboxylesterase
KLIOFDBM_01290 2.6e-233 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KLIOFDBM_01291 1.2e-41 XAC3035 O Glutaredoxin
KLIOFDBM_01292 2.7e-08 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
KLIOFDBM_01293 7.2e-116 XK27_08050 O prohibitin homologues
KLIOFDBM_01294 5.1e-59 S Domain of unknown function (DUF4143)
KLIOFDBM_01295 2.9e-159 S Patatin-like phospholipase
KLIOFDBM_01296 5.7e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KLIOFDBM_01297 6e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KLIOFDBM_01298 3.8e-128 S Vitamin K epoxide reductase
KLIOFDBM_01299 1.5e-169 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
KLIOFDBM_01300 4.7e-32 S Protein of unknown function (DUF3107)
KLIOFDBM_01301 5.5e-300 mphA S Aminoglycoside phosphotransferase
KLIOFDBM_01302 3.8e-290 uvrD2 3.6.4.12 L DNA helicase
KLIOFDBM_01303 3.1e-293 S Zincin-like metallopeptidase
KLIOFDBM_01304 1.7e-157 lon T Belongs to the peptidase S16 family
KLIOFDBM_01305 1.6e-73 S Protein of unknown function (DUF3052)
KLIOFDBM_01307 1e-205 2.7.11.1 NU Tfp pilus assembly protein FimV
KLIOFDBM_01308 1.7e-221 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KLIOFDBM_01309 5.3e-231 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KLIOFDBM_01310 0.0 I acetylesterase activity
KLIOFDBM_01311 8.5e-128 recO L Involved in DNA repair and RecF pathway recombination
KLIOFDBM_01312 3.1e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLIOFDBM_01313 3.8e-134 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01314 1.5e-189 P NMT1/THI5 like
KLIOFDBM_01315 1.4e-223 E Aminotransferase class I and II
KLIOFDBM_01316 3.7e-140 bioM P ATPases associated with a variety of cellular activities
KLIOFDBM_01317 1e-18 2.8.2.22 S Arylsulfotransferase Ig-like domain
KLIOFDBM_01318 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KLIOFDBM_01319 0.0 S Tetratricopeptide repeat
KLIOFDBM_01320 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLIOFDBM_01321 8.1e-202 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KLIOFDBM_01322 2.3e-281 glnA 6.3.1.2 E glutamine synthetase
KLIOFDBM_01323 8.6e-142 S Domain of unknown function (DUF4191)
KLIOFDBM_01324 7.6e-272 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLIOFDBM_01325 2e-101 S Protein of unknown function (DUF3043)
KLIOFDBM_01326 4.4e-258 argE E Peptidase dimerisation domain
KLIOFDBM_01327 1.8e-107 ykoE S ABC-type cobalt transport system, permease component
KLIOFDBM_01328 7e-278 ykoD P ATPases associated with a variety of cellular activities
KLIOFDBM_01329 1.8e-162 cbiQ P Cobalt transport protein
KLIOFDBM_01330 7.9e-160 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLIOFDBM_01331 5e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLIOFDBM_01332 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
KLIOFDBM_01333 4.8e-93
KLIOFDBM_01334 3e-201 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KLIOFDBM_01335 2.6e-211 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KLIOFDBM_01336 8.2e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KLIOFDBM_01337 1.3e-248 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
KLIOFDBM_01338 3.9e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KLIOFDBM_01339 5.9e-83 argR K Regulates arginine biosynthesis genes
KLIOFDBM_01340 1.2e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KLIOFDBM_01341 3e-281 argH 4.3.2.1 E argininosuccinate lyase
KLIOFDBM_01342 7.9e-28 thiS 2.8.1.10 H ThiS family
KLIOFDBM_01343 1.8e-156 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KLIOFDBM_01344 5e-145 moeB 2.7.7.80 H ThiF family
KLIOFDBM_01345 3.3e-64 M1-798 P Rhodanese Homology Domain
KLIOFDBM_01346 4.6e-102 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLIOFDBM_01347 3.9e-139 S Putative ABC-transporter type IV
KLIOFDBM_01348 9.1e-82 S Protein of unknown function (DUF975)
KLIOFDBM_01349 2.6e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLIOFDBM_01350 3.6e-18 L Tetratricopeptide repeat
KLIOFDBM_01352 5.6e-158 S Sucrose-6F-phosphate phosphohydrolase
KLIOFDBM_01353 5.1e-176 metQ P NLPA lipoprotein
KLIOFDBM_01354 1.4e-220 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLIOFDBM_01355 7.4e-113 metI P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01356 4.1e-225 S Peptidase dimerisation domain
KLIOFDBM_01357 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KLIOFDBM_01358 1e-37
KLIOFDBM_01359 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KLIOFDBM_01360 8.7e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLIOFDBM_01361 1.4e-118 S Protein of unknown function (DUF3000)
KLIOFDBM_01362 3.4e-252 rnd 3.1.13.5 J 3'-5' exonuclease
KLIOFDBM_01363 4.4e-234 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLIOFDBM_01364 2.4e-243 clcA_2 P Voltage gated chloride channel
KLIOFDBM_01365 3.4e-59
KLIOFDBM_01366 6.5e-116 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLIOFDBM_01367 7.3e-121 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLIOFDBM_01368 1.3e-249 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLIOFDBM_01369 9.8e-12 adhC 1.1.1.1, 1.1.1.284 C Has high formaldehyde dehydrogenase activity in the presence of glutathione and catalyzes the oxidation of normal alcohols in a reaction that is not GSH-dependent
KLIOFDBM_01370 5e-27 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLIOFDBM_01371 5.1e-33 cpdA 2.1.2.2, 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KLIOFDBM_01372 4.9e-70 L IstB-like ATP binding protein
KLIOFDBM_01373 1.7e-59 L IstB-like ATP binding protein
KLIOFDBM_01374 9.3e-176 5.1.3.37 P Domain of unknown function (DUF4143)
KLIOFDBM_01375 1.4e-49 L Transposase
KLIOFDBM_01376 2.1e-24 L PFAM Integrase catalytic
KLIOFDBM_01377 1.4e-131 L IstB-like ATP binding protein
KLIOFDBM_01378 5.2e-211 L PFAM Integrase catalytic
KLIOFDBM_01379 5.3e-79 L PFAM Integrase catalytic
KLIOFDBM_01380 9.4e-97 K Transposase IS116 IS110 IS902
KLIOFDBM_01381 1.5e-43 L Psort location Cytoplasmic, score
KLIOFDBM_01382 1.3e-89 L Transposase
KLIOFDBM_01383 5.6e-48 L Transposase, Mutator family
KLIOFDBM_01384 8.8e-67
KLIOFDBM_01385 7.9e-87
KLIOFDBM_01386 6.9e-14 L PFAM Integrase catalytic
KLIOFDBM_01387 1.6e-65 L Helix-turn-helix domain
KLIOFDBM_01388 5.9e-53 L Helix-turn-helix domain
KLIOFDBM_01389 4.6e-106 S Sulfite exporter TauE/SafE
KLIOFDBM_01390 1.2e-271 aslB C Iron-sulfur cluster-binding domain
KLIOFDBM_01391 2.1e-311 P Domain of unknown function (DUF4976)
KLIOFDBM_01392 1.4e-251 gtr U Sugar (and other) transporter
KLIOFDBM_01393 2.4e-158 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
KLIOFDBM_01394 5.5e-217 GK ROK family
KLIOFDBM_01395 3.1e-173 2.7.1.2 GK ROK family
KLIOFDBM_01396 1.2e-146 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLIOFDBM_01397 2.8e-243 nagA 3.5.1.25 G Amidohydrolase family
KLIOFDBM_01398 1.1e-251 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KLIOFDBM_01399 2.4e-20 EGP Transmembrane secretion effector
KLIOFDBM_01402 9.1e-107 pepE 3.4.13.21 E Belongs to the peptidase S51 family
KLIOFDBM_01403 4.6e-70 S Putative DNA-binding domain
KLIOFDBM_01404 5.2e-28
KLIOFDBM_01406 3.7e-16
KLIOFDBM_01407 1.1e-300 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KLIOFDBM_01408 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KLIOFDBM_01409 3e-262 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLIOFDBM_01410 6.5e-66 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KLIOFDBM_01411 2.7e-134 3.1.3.85 G Phosphoglycerate mutase family
KLIOFDBM_01412 4.1e-18 L Helix-turn-helix domain
KLIOFDBM_01413 1.1e-180 C Polysaccharide pyruvyl transferase
KLIOFDBM_01414 2.2e-132 GT2 M Glycosyltransferase like family 2
KLIOFDBM_01415 2.8e-148 1.13.11.79 C Psort location Cytoplasmic, score 8.87
KLIOFDBM_01416 6.1e-175 wbbI M transferase activity, transferring glycosyl groups
KLIOFDBM_01417 4.2e-222 S Psort location CytoplasmicMembrane, score 9.99
KLIOFDBM_01418 2.4e-27 S Psort location CytoplasmicMembrane, score 9.99
KLIOFDBM_01419 8.6e-155 S Glycosyl transferase family 2
KLIOFDBM_01420 9.2e-26 cps1D M Domain of unknown function (DUF4422)
KLIOFDBM_01421 2.2e-19 cps1D M Domain of unknown function (DUF4422)
KLIOFDBM_01422 1.6e-32 L Psort location Cytoplasmic, score 8.87
KLIOFDBM_01423 1e-87 L IstB-like ATP binding protein
KLIOFDBM_01425 2.4e-50 L Transposase and inactivated derivatives IS30 family
KLIOFDBM_01426 2.5e-218 L Transposase, Mutator family
KLIOFDBM_01427 2.2e-51 S Phage derived protein Gp49-like (DUF891)
KLIOFDBM_01428 3.3e-38 K Addiction module
KLIOFDBM_01430 5e-80 ybfG M Domain of unknown function (DUF1906)
KLIOFDBM_01431 7e-153 P Belongs to the ABC transporter superfamily
KLIOFDBM_01432 2.1e-88 appC EP PFAM binding-protein-dependent transport systems inner membrane component
KLIOFDBM_01433 4.7e-121 appB P PFAM binding-protein-dependent transport systems inner membrane component
KLIOFDBM_01434 3.4e-191 oppA5 E family 5
KLIOFDBM_01435 3.1e-22 trxB1 1.8.1.9 C Thioredoxin domain
KLIOFDBM_01436 1.1e-81 trxB1 1.8.1.9 C Thioredoxin domain
KLIOFDBM_01437 6e-29 engB D Necessary for normal cell division and for the maintenance of normal septation
KLIOFDBM_01438 3.2e-166 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
KLIOFDBM_01439 1.3e-232 malE G Bacterial extracellular solute-binding protein
KLIOFDBM_01440 2.4e-251 malF G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01441 2.6e-161 malG G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01442 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KLIOFDBM_01443 3.1e-173 S HAD-hyrolase-like
KLIOFDBM_01444 4.2e-144 traX S TraX protein
KLIOFDBM_01445 2.6e-194 K Psort location Cytoplasmic, score
KLIOFDBM_01446 2.5e-56
KLIOFDBM_01447 2.2e-20
KLIOFDBM_01448 3.5e-32
KLIOFDBM_01450 4.8e-39 S AAA domain, putative AbiEii toxin, Type IV TA system
KLIOFDBM_01451 1.1e-30 S AAA domain, putative AbiEii toxin, Type IV TA system
KLIOFDBM_01452 4.7e-103 insK L Integrase core domain
KLIOFDBM_01454 1.6e-07 lldD 1.1.2.3 C Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain
KLIOFDBM_01455 6.8e-18 mtlD 1.1.1.17 G Mannitol dehydrogenase Rossmann domain
KLIOFDBM_01456 4.8e-65 S Predicted membrane protein (DUF2142)
KLIOFDBM_01457 1.1e-172 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KLIOFDBM_01459 1.7e-190 M Glycosyltransferase like family 2
KLIOFDBM_01460 7.6e-115 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KLIOFDBM_01461 9.2e-186 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
KLIOFDBM_01462 5.3e-125
KLIOFDBM_01463 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLIOFDBM_01464 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLIOFDBM_01465 0.0 E Transglutaminase-like superfamily
KLIOFDBM_01466 1.1e-237 S Protein of unknown function DUF58
KLIOFDBM_01467 0.0 S Fibronectin type 3 domain
KLIOFDBM_01468 1.2e-221 KLT Protein tyrosine kinase
KLIOFDBM_01469 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
KLIOFDBM_01470 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
KLIOFDBM_01471 6.1e-233 G Major Facilitator Superfamily
KLIOFDBM_01472 7.1e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLIOFDBM_01473 1.7e-165 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KLIOFDBM_01474 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLIOFDBM_01475 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
KLIOFDBM_01476 8.9e-259 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLIOFDBM_01477 1.1e-121 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLIOFDBM_01478 8.5e-268 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
KLIOFDBM_01479 1e-204 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KLIOFDBM_01480 4.8e-192 ftsE D Cell division ATP-binding protein FtsE
KLIOFDBM_01481 9.8e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
KLIOFDBM_01482 3.2e-144 usp 3.5.1.28 CBM50 D CHAP domain protein
KLIOFDBM_01483 9.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KLIOFDBM_01484 1.6e-142 pknD ET ABC transporter, substrate-binding protein, family 3
KLIOFDBM_01485 5.8e-169 pknD ET ABC transporter, substrate-binding protein, family 3
KLIOFDBM_01486 8e-153 yecS E Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01487 1.4e-150 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
KLIOFDBM_01488 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KLIOFDBM_01489 5.3e-158 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
KLIOFDBM_01490 3.3e-186 K Periplasmic binding protein domain
KLIOFDBM_01491 1.4e-167 malC G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01492 1.2e-167 G ABC transporter permease
KLIOFDBM_01493 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KLIOFDBM_01494 1.7e-259 G Bacterial extracellular solute-binding protein
KLIOFDBM_01495 4e-278 G Bacterial extracellular solute-binding protein
KLIOFDBM_01496 4.5e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KLIOFDBM_01497 1.9e-292 E ABC transporter, substrate-binding protein, family 5
KLIOFDBM_01498 7.4e-167 P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01499 1.1e-146 EP Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01500 5.5e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
KLIOFDBM_01501 2.4e-136 sapF E ATPases associated with a variety of cellular activities
KLIOFDBM_01502 1.8e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
KLIOFDBM_01503 3.5e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KLIOFDBM_01504 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KLIOFDBM_01505 2.7e-93 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KLIOFDBM_01506 6.5e-104 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KLIOFDBM_01507 4.3e-272 yhdG E aromatic amino acid transport protein AroP K03293
KLIOFDBM_01508 2.9e-262 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLIOFDBM_01509 2.9e-243 dgt 3.1.5.1 F Phosphohydrolase-associated domain
KLIOFDBM_01510 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KLIOFDBM_01511 1.8e-69 S PIN domain
KLIOFDBM_01512 1e-34
KLIOFDBM_01513 3.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KLIOFDBM_01514 1.1e-115 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KLIOFDBM_01515 1.6e-293 EK Alanine-glyoxylate amino-transferase
KLIOFDBM_01516 3.8e-210 ybiR P Citrate transporter
KLIOFDBM_01517 3.3e-30
KLIOFDBM_01518 3.5e-42 G Alpha-L-arabinofuranosidase C-terminal domain
KLIOFDBM_01519 3.1e-156 K Helix-turn-helix domain, rpiR family
KLIOFDBM_01522 4.3e-258 G Bacterial extracellular solute-binding protein
KLIOFDBM_01523 9.9e-225 K helix_turn _helix lactose operon repressor
KLIOFDBM_01524 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KLIOFDBM_01525 4.5e-13 L Psort location Cytoplasmic, score 8.87
KLIOFDBM_01526 0.0 E ABC transporter, substrate-binding protein, family 5
KLIOFDBM_01527 1.9e-86 msrA 1.8.4.11, 1.8.4.12 O peptide-methionine (S)-S-oxide reductase activity
KLIOFDBM_01528 4e-134 V ATPases associated with a variety of cellular activities
KLIOFDBM_01529 8e-177 M Conserved repeat domain
KLIOFDBM_01530 5.6e-278 macB_8 V MacB-like periplasmic core domain
KLIOFDBM_01531 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KLIOFDBM_01532 2.4e-181 adh3 C Zinc-binding dehydrogenase
KLIOFDBM_01533 6.2e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KLIOFDBM_01534 1.1e-222 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLIOFDBM_01535 8.9e-69 zur P Belongs to the Fur family
KLIOFDBM_01536 3.2e-143 P Zinc-uptake complex component A periplasmic
KLIOFDBM_01537 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KLIOFDBM_01538 1.5e-294 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
KLIOFDBM_01539 9.1e-242 purD 6.3.4.13 F Belongs to the GARS family
KLIOFDBM_01540 1.6e-183 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KLIOFDBM_01541 7.9e-293 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KLIOFDBM_01542 1.2e-299 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
KLIOFDBM_01543 3.5e-32
KLIOFDBM_01544 1.2e-13 C Aldo/keto reductase family
KLIOFDBM_01545 1.1e-101 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
KLIOFDBM_01546 6.6e-111 Q D-alanine [D-alanyl carrier protein] ligase activity
KLIOFDBM_01547 2.8e-252 Q D-alanine [D-alanyl carrier protein] ligase activity
KLIOFDBM_01548 8.2e-222 I alpha/beta hydrolase fold
KLIOFDBM_01549 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
KLIOFDBM_01550 3.6e-137 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KLIOFDBM_01551 3.6e-225 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KLIOFDBM_01552 1.9e-45 L Integrase core domain
KLIOFDBM_01553 2.1e-118 EGP Major Facilitator Superfamily
KLIOFDBM_01554 5.5e-137 EGP Major Facilitator Superfamily
KLIOFDBM_01556 1.9e-115 K WHG domain
KLIOFDBM_01557 6.5e-111 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
KLIOFDBM_01558 2.2e-60 L PFAM Integrase catalytic
KLIOFDBM_01559 2.9e-15 S COG NOG14600 non supervised orthologous group
KLIOFDBM_01560 9.8e-296 L PFAM Integrase catalytic
KLIOFDBM_01561 3.6e-148 L IstB-like ATP binding protein
KLIOFDBM_01562 4.3e-171 G Acyltransferase family
KLIOFDBM_01563 1.1e-209 EGP Transmembrane secretion effector
KLIOFDBM_01564 8.6e-56 KLT Protein tyrosine kinase
KLIOFDBM_01567 3e-228 2.7.7.7 L Transposase and inactivated derivatives
KLIOFDBM_01568 5.5e-186 insH5 L COG3039 Transposase and inactivated derivatives IS5 family
KLIOFDBM_01569 6.6e-30 argK E Binds and hydrolyzes GTP. Likely functions as a G-protein chaperone that assists AdoCbl cofactor delivery to the methylmalonyl-CoA mutase (MCM) ScpA and reactivation of the enzyme during catalysis
KLIOFDBM_01570 0.0 trxB2 1.8.1.9 C Thioredoxin domain
KLIOFDBM_01571 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
KLIOFDBM_01572 2.4e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KLIOFDBM_01573 5.5e-206 S AAA ATPase domain
KLIOFDBM_01574 5.7e-234 ytfL P Transporter associated domain
KLIOFDBM_01575 1.2e-82 dps P Belongs to the Dps family
KLIOFDBM_01576 6.7e-256 S Domain of unknown function (DUF4143)
KLIOFDBM_01577 9.3e-121 S Protein of unknown function DUF45
KLIOFDBM_01580 7.4e-17 S Domain of unknown function (DUF4143)
KLIOFDBM_01581 5.3e-197 S Psort location CytoplasmicMembrane, score
KLIOFDBM_01582 2.8e-257 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KLIOFDBM_01583 5.2e-203 V VanZ like family
KLIOFDBM_01584 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KLIOFDBM_01585 1.4e-15 lacS G Psort location CytoplasmicMembrane, score 10.00
KLIOFDBM_01586 4.5e-183 lacR K Transcriptional regulator, LacI family
KLIOFDBM_01587 9.3e-50 S Transmembrane domain of unknown function (DUF3566)
KLIOFDBM_01588 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLIOFDBM_01589 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLIOFDBM_01590 4.2e-83 S Protein of unknown function (DUF721)
KLIOFDBM_01591 1.1e-201 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLIOFDBM_01592 5.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KLIOFDBM_01593 3.3e-280 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KLIOFDBM_01594 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KLIOFDBM_01595 2.9e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KLIOFDBM_01596 9.3e-181 yidC U Membrane protein insertase, YidC Oxa1 family
KLIOFDBM_01597 3e-93 jag S Putative single-stranded nucleic acids-binding domain
KLIOFDBM_01598 3.4e-123 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KLIOFDBM_01599 8.1e-174 parA D CobQ CobB MinD ParA nucleotide binding domain protein
KLIOFDBM_01600 1e-221 parB K Belongs to the ParB family
KLIOFDBM_01601 3.5e-175 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KLIOFDBM_01602 0.0 murJ KLT MviN-like protein
KLIOFDBM_01603 0.0
KLIOFDBM_01604 2.3e-160 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
KLIOFDBM_01605 2.7e-282 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
KLIOFDBM_01606 3.1e-110 S LytR cell envelope-related transcriptional attenuator
KLIOFDBM_01607 1.3e-173 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KLIOFDBM_01608 2.2e-168 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KLIOFDBM_01609 4.8e-215 S G5
KLIOFDBM_01611 2e-135 O Thioredoxin
KLIOFDBM_01612 0.0 KLT Protein tyrosine kinase
KLIOFDBM_01613 3.9e-119 3.2.1.21 GH3 G Fibronectin type III-like domain
KLIOFDBM_01614 2.7e-118 T LytTr DNA-binding domain
KLIOFDBM_01615 1.7e-134 T GHKL domain
KLIOFDBM_01616 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
KLIOFDBM_01617 7.7e-50 kcsA U Ion channel
KLIOFDBM_01618 3.8e-125 S Protein of unknown function (DUF3990)
KLIOFDBM_01619 3.1e-121 K Helix-turn-helix XRE-family like proteins
KLIOFDBM_01620 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
KLIOFDBM_01621 8.3e-122 S Psort location CytoplasmicMembrane, score
KLIOFDBM_01623 2e-42 nrdH O Glutaredoxin
KLIOFDBM_01624 6e-88 nrdI F Probably involved in ribonucleotide reductase function
KLIOFDBM_01625 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLIOFDBM_01627 1.3e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLIOFDBM_01628 1.2e-216 2.4.1.166 GT2 M Glycosyltransferase like family 2
KLIOFDBM_01629 2.1e-73 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KLIOFDBM_01630 1.1e-44 ulaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
KLIOFDBM_01631 4.9e-241 ulaA 2.7.1.194 S PTS system sugar-specific permease component
KLIOFDBM_01632 6e-137 K UTRA domain
KLIOFDBM_01633 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
KLIOFDBM_01634 9.1e-26 tnp3514b L Winged helix-turn helix
KLIOFDBM_01636 2.2e-185
KLIOFDBM_01637 3.8e-142 U Branched-chain amino acid transport system / permease component
KLIOFDBM_01638 7.9e-179 3.6.3.17 G ATPases associated with a variety of cellular activities
KLIOFDBM_01639 4.2e-146 G Periplasmic binding protein domain
KLIOFDBM_01640 1.5e-131 K helix_turn _helix lactose operon repressor
KLIOFDBM_01641 7.6e-18 tnp7109-21 L Integrase core domain
KLIOFDBM_01642 1.3e-287 S LPXTG-motif cell wall anchor domain protein
KLIOFDBM_01643 8.4e-261 M LPXTG-motif cell wall anchor domain protein
KLIOFDBM_01644 8.5e-179 3.4.22.70 M Sortase family
KLIOFDBM_01645 4.2e-136
KLIOFDBM_01646 2.3e-270 KLT Domain of unknown function (DUF4032)
KLIOFDBM_01647 4.2e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KLIOFDBM_01648 1.8e-164 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
KLIOFDBM_01649 6.4e-174 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLIOFDBM_01650 7.4e-43
KLIOFDBM_01651 7.7e-125 I alpha/beta hydrolase fold
KLIOFDBM_01652 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
KLIOFDBM_01653 8.6e-25
KLIOFDBM_01654 1e-110 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
KLIOFDBM_01655 1.1e-150
KLIOFDBM_01656 1.1e-146 ypfH S Phospholipase/Carboxylesterase
KLIOFDBM_01657 4.7e-119 S membrane transporter protein
KLIOFDBM_01658 0.0 yjcE P Sodium/hydrogen exchanger family
KLIOFDBM_01659 9.8e-79 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KLIOFDBM_01660 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
KLIOFDBM_01661 3.8e-229 nagC GK ROK family
KLIOFDBM_01662 3.8e-243 msmE7 G Bacterial extracellular solute-binding protein
KLIOFDBM_01663 4.7e-147 malC G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01664 2.9e-154 G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01665 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KLIOFDBM_01666 1.5e-231 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
KLIOFDBM_01667 6.4e-142 cobB2 K Sir2 family
KLIOFDBM_01668 2.5e-106 L Transposase and inactivated derivatives IS30 family
KLIOFDBM_01670 6.1e-48 L IS1 transposase
KLIOFDBM_01671 4.6e-67 L Integrase core domain
KLIOFDBM_01672 5.6e-38 KT Primase C terminal 1 (PriCT-1)
KLIOFDBM_01673 5.8e-30 artP P Part of the ABC transporter complex ArtPIQMJ involved in arginine transport. Probably responsible for energy coupling to the transport system
KLIOFDBM_01674 1e-26 L PFAM Integrase catalytic
KLIOFDBM_01676 4.9e-137 L Tetratricopeptide repeat
KLIOFDBM_01677 3.2e-200 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KLIOFDBM_01679 5.5e-141 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KLIOFDBM_01680 1.4e-95
KLIOFDBM_01681 1.3e-49 trkA P TrkA-N domain
KLIOFDBM_01682 1.9e-41 trkB P Cation transport protein
KLIOFDBM_01683 9.6e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLIOFDBM_01684 0.0 recN L May be involved in recombinational repair of damaged DNA
KLIOFDBM_01685 5e-119 S Haloacid dehalogenase-like hydrolase
KLIOFDBM_01686 6e-13 J Acetyltransferase (GNAT) domain
KLIOFDBM_01687 2.3e-18 J Acetyltransferase (GNAT) domain
KLIOFDBM_01688 4.8e-58 K helix_turn_helix gluconate operon transcriptional repressor
KLIOFDBM_01689 1.1e-172 V ATPases associated with a variety of cellular activities
KLIOFDBM_01690 1.7e-120 S ABC-2 family transporter protein
KLIOFDBM_01691 3.7e-107
KLIOFDBM_01692 8.8e-25 pacL2 3.6.3.8 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KLIOFDBM_01693 7.8e-71 K helix_turn_helix gluconate operon transcriptional repressor
KLIOFDBM_01694 3.1e-196 S Protein of unknown function (DUF1648)
KLIOFDBM_01695 8.6e-284 thrC 4.2.3.1 E Threonine synthase N terminus
KLIOFDBM_01696 2.9e-235 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLIOFDBM_01697 3e-96
KLIOFDBM_01698 7.8e-137 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLIOFDBM_01699 8e-130 S TIGRFAM TIGR03943 family protein
KLIOFDBM_01700 6.4e-167 ycgR S Predicted permease
KLIOFDBM_01702 1.8e-151 P Zinc-uptake complex component A periplasmic
KLIOFDBM_01703 8.6e-12 P Zinc-uptake complex component A periplasmic
KLIOFDBM_01704 0.0 S Uncharacterised protein family (UPF0182)
KLIOFDBM_01705 4.3e-90 2.3.1.183 M Acetyltransferase (GNAT) domain
KLIOFDBM_01706 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KLIOFDBM_01707 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLIOFDBM_01708 1e-178 1.1.1.65 C Aldo/keto reductase family
KLIOFDBM_01709 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KLIOFDBM_01710 1.6e-63 divIC D Septum formation initiator
KLIOFDBM_01711 6.3e-102 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
KLIOFDBM_01712 5.8e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KLIOFDBM_01714 2.6e-81 L HTH-like domain
KLIOFDBM_01715 2.8e-80 insK L Integrase core domain
KLIOFDBM_01716 9.2e-45 L Helix-turn-helix domain
KLIOFDBM_01717 2.4e-88 pin L Resolvase, N terminal domain
KLIOFDBM_01718 8.6e-211 G Bacterial extracellular solute-binding protein
KLIOFDBM_01719 3.3e-126 P Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01720 4.4e-128 P Binding-protein-dependent transport systems inner membrane component
KLIOFDBM_01721 7.4e-258 M Protein of unknown function (DUF2961)
KLIOFDBM_01722 7.9e-237 bfrA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
KLIOFDBM_01723 3.8e-147 K helix_turn _helix lactose operon repressor
KLIOFDBM_01724 8.8e-49 L PFAM Integrase catalytic
KLIOFDBM_01725 3.9e-87 L PFAM Integrase catalytic
KLIOFDBM_01727 1.6e-121 XK27_00240 K Fic/DOC family
KLIOFDBM_01728 2.3e-07
KLIOFDBM_01729 1.1e-33
KLIOFDBM_01732 1.3e-07
KLIOFDBM_01735 2.6e-87 int8 L Phage integrase family
KLIOFDBM_01736 2.5e-40 int8 L Phage integrase family
KLIOFDBM_01737 3.2e-93
KLIOFDBM_01738 6.7e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
KLIOFDBM_01739 1.4e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
KLIOFDBM_01740 4.4e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLIOFDBM_01741 5.9e-145 yplQ S Haemolysin-III related
KLIOFDBM_01742 7.5e-280 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KLIOFDBM_01743 4.9e-47 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KLIOFDBM_01744 0.0 D FtsK/SpoIIIE family
KLIOFDBM_01745 2.1e-204 K Cell envelope-related transcriptional attenuator domain
KLIOFDBM_01746 1.8e-55 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KLIOFDBM_01747 0.0 S Glycosyl transferase, family 2
KLIOFDBM_01748 1.1e-262
KLIOFDBM_01749 6.3e-78 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
KLIOFDBM_01750 2.2e-148 cof 5.2.1.8 T Eukaryotic phosphomannomutase
KLIOFDBM_01751 2e-129 ctsW S Phosphoribosyl transferase domain
KLIOFDBM_01752 9.8e-197 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KLIOFDBM_01753 1e-128 T Response regulator receiver domain protein
KLIOFDBM_01754 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KLIOFDBM_01755 2.1e-100 carD K CarD-like/TRCF domain
KLIOFDBM_01756 1.1e-87 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KLIOFDBM_01757 4.4e-136 znuB U ABC 3 transport family
KLIOFDBM_01758 1.9e-161 znuC P ATPases associated with a variety of cellular activities
KLIOFDBM_01759 3e-183 P Zinc-uptake complex component A periplasmic
KLIOFDBM_01760 1.1e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KLIOFDBM_01761 1.2e-253 rpsA J Ribosomal protein S1
KLIOFDBM_01762 2.3e-105 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KLIOFDBM_01763 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KLIOFDBM_01764 2.1e-177 terC P Integral membrane protein, TerC family
KLIOFDBM_01765 2.7e-274 pyk 2.7.1.40 G Pyruvate kinase
KLIOFDBM_01766 9.1e-107 aspA 3.6.1.13 L NUDIX domain
KLIOFDBM_01768 1.2e-122 pdtaR T Response regulator receiver domain protein
KLIOFDBM_01769 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLIOFDBM_01770 5.1e-178 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
KLIOFDBM_01771 4e-127 3.6.1.13 L NUDIX domain
KLIOFDBM_01772 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KLIOFDBM_01773 1.3e-25 zntR K bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
KLIOFDBM_01774 6.9e-89 K Putative zinc ribbon domain
KLIOFDBM_01775 3.5e-120 S GyrI-like small molecule binding domain
KLIOFDBM_01777 6.2e-20 tag 3.2.2.20 L Methyladenine glycosylase
KLIOFDBM_01779 1.9e-214 ykiI
KLIOFDBM_01780 6.6e-251 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KLIOFDBM_01781 1.1e-231 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLIOFDBM_01782 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KLIOFDBM_01784 3.2e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLIOFDBM_01785 0.0 XK27_09800 I Psort location CytoplasmicMembrane, score 9.99
KLIOFDBM_01787 2.3e-176 V Abi-like protein
KLIOFDBM_01788 3.2e-27 yjdF S Protein of unknown function (DUF2992)
KLIOFDBM_01789 7.2e-36 S Conjugal transfer protein TraD
KLIOFDBM_01790 4e-66 rsmJ 2.1.1.242 J Specifically methylates the guanosine in position 1516 of 16S rRNA
KLIOFDBM_01791 2.5e-09 pyk 2.7.1.40 G Belongs to the pyruvate kinase family
KLIOFDBM_01792 3.6e-137 sigH K Belongs to the sigma-70 factor family. ECF subfamily
KLIOFDBM_01793 5.6e-52
KLIOFDBM_01794 1.1e-186 galM 5.1.3.3 G Aldose 1-epimerase
KLIOFDBM_01795 2.1e-190 galM 5.1.3.3 G Aldose 1-epimerase
KLIOFDBM_01796 7.5e-183 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KLIOFDBM_01797 4.2e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KLIOFDBM_01798 1.4e-195 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLIOFDBM_01799 1.6e-134 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
KLIOFDBM_01800 1.1e-11 S Spermine/spermidine synthase domain
KLIOFDBM_01801 1.7e-113 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KLIOFDBM_01802 6.2e-25 rpmI J Ribosomal protein L35
KLIOFDBM_01803 2.1e-61 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KLIOFDBM_01804 1.5e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KLIOFDBM_01805 7.6e-145 xerD D recombinase XerD
KLIOFDBM_01806 1.4e-149 soj D CobQ CobB MinD ParA nucleotide binding domain protein
KLIOFDBM_01807 2.4e-151 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KLIOFDBM_01808 4.4e-116 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KLIOFDBM_01809 1.8e-153 nrtR 3.6.1.55 F NUDIX hydrolase
KLIOFDBM_01810 7e-250 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KLIOFDBM_01811 2.8e-296 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KLIOFDBM_01812 1.5e-161 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
KLIOFDBM_01813 8.1e-238 iscS1 2.8.1.7 E Aminotransferase class-V
KLIOFDBM_01814 4.5e-19 naiP U Sugar (and other) transporter
KLIOFDBM_01815 0.0 V FtsX-like permease family
KLIOFDBM_01816 1.1e-136 V ATPases associated with a variety of cellular activities
KLIOFDBM_01817 2.6e-106 K Virulence activator alpha C-term
KLIOFDBM_01818 0.0 typA T Elongation factor G C-terminus
KLIOFDBM_01819 1.4e-77
KLIOFDBM_01820 1.5e-188 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
KLIOFDBM_01821 1.2e-188 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
KLIOFDBM_01822 1.7e-41
KLIOFDBM_01823 0.0 MV MacB-like periplasmic core domain
KLIOFDBM_01824 4.9e-148 V ABC transporter, ATP-binding protein
KLIOFDBM_01825 2.1e-188 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KLIOFDBM_01826 2.9e-309 E ABC transporter, substrate-binding protein, family 5
KLIOFDBM_01827 8.9e-154 dppB EP Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01828 1.9e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
KLIOFDBM_01829 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
KLIOFDBM_01830 3.3e-171 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
KLIOFDBM_01831 4e-145 S Protein of unknown function (DUF3710)
KLIOFDBM_01832 3.8e-134 S Protein of unknown function (DUF3159)
KLIOFDBM_01833 1.2e-241 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLIOFDBM_01834 1.4e-96
KLIOFDBM_01835 0.0 ctpE P E1-E2 ATPase
KLIOFDBM_01836 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KLIOFDBM_01837 1.1e-118 E Psort location Cytoplasmic, score 8.87
KLIOFDBM_01838 1.4e-81 K helix_turn_helix, Lux Regulon
KLIOFDBM_01839 9.7e-136 ybhL S Belongs to the BI1 family
KLIOFDBM_01840 3.1e-165 ydeD EG EamA-like transporter family
KLIOFDBM_01841 6.9e-145 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
KLIOFDBM_01842 1.3e-276 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KLIOFDBM_01843 2.1e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLIOFDBM_01844 2.2e-151 fic D Fic/DOC family
KLIOFDBM_01845 0.0 ftsK D FtsK SpoIIIE family protein
KLIOFDBM_01846 3.5e-117 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLIOFDBM_01847 7.4e-95 cinA 3.5.1.42 S Belongs to the CinA family
KLIOFDBM_01848 7.6e-78 K Helix-turn-helix XRE-family like proteins
KLIOFDBM_01849 7e-39 S Protein of unknown function (DUF3046)
KLIOFDBM_01850 1.1e-196 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLIOFDBM_01851 1.1e-101 recX S Modulates RecA activity
KLIOFDBM_01852 2.4e-113 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLIOFDBM_01853 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KLIOFDBM_01854 6.7e-190 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KLIOFDBM_01855 2e-118
KLIOFDBM_01856 6.2e-131 plsC2 2.3.1.51 I Phosphate acyltransferases
KLIOFDBM_01857 0.0 pknL 2.7.11.1 KLT PASTA
KLIOFDBM_01858 2.1e-194 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
KLIOFDBM_01859 3.2e-110
KLIOFDBM_01860 1.4e-190 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KLIOFDBM_01861 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KLIOFDBM_01862 2.2e-221 G Major Facilitator Superfamily
KLIOFDBM_01863 8.3e-171 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLIOFDBM_01864 0.0 lhr L DEAD DEAH box helicase
KLIOFDBM_01865 1.2e-48 K Psort location Cytoplasmic, score
KLIOFDBM_01866 5.2e-43 K Psort location Cytoplasmic, score
KLIOFDBM_01867 2.3e-42 K AraC-like ligand binding domain
KLIOFDBM_01868 3.1e-104 G Bacterial extracellular solute-binding protein
KLIOFDBM_01869 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KLIOFDBM_01870 1.5e-233 S Type I phosphodiesterase / nucleotide pyrophosphatase
KLIOFDBM_01871 1.3e-148 S Protein of unknown function (DUF3071)
KLIOFDBM_01872 1.4e-47 S Domain of unknown function (DUF4193)
KLIOFDBM_01873 5.5e-83 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KLIOFDBM_01874 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLIOFDBM_01875 1.6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLIOFDBM_01876 2.3e-74
KLIOFDBM_01878 6.3e-238 S HipA-like C-terminal domain
KLIOFDBM_01879 5e-50 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KLIOFDBM_01881 3.3e-26
KLIOFDBM_01882 5.9e-143 fic D Fic/DOC family
KLIOFDBM_01883 2.8e-30 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KLIOFDBM_01884 2.3e-23 hinT FG Hydrolyzes purine nucleotide phosphoramidates, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate), guanosine 5'monophosphomorpholidate (GMP-morpholidate) and tryptamine 5'guanosine monophosphate (TpGd). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha- acetyl lysine methyl ester)) generated by lysine--tRNA ligase, and lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)). Is essential for the activity of the enzyme D- alanine dehydrogenase (DadA) and is required for E.coli to grow on D-alanine as a sole carbon source. Is also required for growth at high salt concentrations
KLIOFDBM_01885 1.4e-12 psuG 4.2.1.70 Q Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway
KLIOFDBM_01886 2.2e-26 KT Primase C terminal 1 (PriCT-1)
KLIOFDBM_01887 8.8e-15 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLIOFDBM_01888 1.6e-168 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KLIOFDBM_01889 0.0 gcs2 S A circularly permuted ATPgrasp
KLIOFDBM_01890 7.4e-149 E Transglutaminase/protease-like homologues
KLIOFDBM_01892 2.6e-101 K helix_turn _helix lactose operon repressor
KLIOFDBM_01893 8.9e-125
KLIOFDBM_01894 1.4e-184 nusA K Participates in both transcription termination and antitermination
KLIOFDBM_01895 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLIOFDBM_01896 4e-81 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KLIOFDBM_01897 5.4e-220 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLIOFDBM_01898 2.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
KLIOFDBM_01899 3.6e-261 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLIOFDBM_01900 1e-97
KLIOFDBM_01902 9.1e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KLIOFDBM_01903 1e-172 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLIOFDBM_01904 3.3e-275 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KLIOFDBM_01905 2.1e-73 K Transcriptional regulator
KLIOFDBM_01906 1.5e-197 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KLIOFDBM_01907 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KLIOFDBM_01908 0.0 crr 2.7.1.193 G pts system, glucose-specific IIABC component
KLIOFDBM_01909 5.9e-163 arbG K CAT RNA binding domain
KLIOFDBM_01910 6.5e-200 I Diacylglycerol kinase catalytic domain
KLIOFDBM_01911 3.3e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLIOFDBM_01913 5.5e-250 G Bacterial extracellular solute-binding protein
KLIOFDBM_01914 6.9e-173 malC G Binding-protein-dependent transport system inner membrane component
KLIOFDBM_01915 2.5e-167 G ABC transporter permease
KLIOFDBM_01916 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
KLIOFDBM_01917 6.3e-204 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
KLIOFDBM_01918 4.5e-167 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLIOFDBM_01919 4.4e-118 degU K helix_turn_helix, Lux Regulon
KLIOFDBM_01920 7.6e-236 tcsS3 KT PspC domain
KLIOFDBM_01921 4.8e-283 pspC KT PspC domain
KLIOFDBM_01922 1.9e-66
KLIOFDBM_01923 0.0 S alpha beta
KLIOFDBM_01924 1.4e-110 S Protein of unknown function (DUF4125)
KLIOFDBM_01925 0.0 S Domain of unknown function (DUF4037)
KLIOFDBM_01926 8.9e-215 araJ EGP Major facilitator Superfamily
KLIOFDBM_01928 4.7e-311 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KLIOFDBM_01929 1.2e-174 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KLIOFDBM_01930 1.1e-138 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLIOFDBM_01931 5.4e-116 phoU P Plays a role in the regulation of phosphate uptake
KLIOFDBM_01932 6.9e-170 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KLIOFDBM_01933 8.1e-33
KLIOFDBM_01934 4.4e-211 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KLIOFDBM_01935 1.7e-168 usp 3.5.1.28 CBM50 S CHAP domain
KLIOFDBM_01936 1.4e-101 M NlpC/P60 family
KLIOFDBM_01937 1.5e-103 M NlpC/P60 family
KLIOFDBM_01938 1.6e-10 M NlpC/P60 family
KLIOFDBM_01939 2.1e-188 T Universal stress protein family
KLIOFDBM_01940 3.4e-73 attW O OsmC-like protein
KLIOFDBM_01941 7.8e-168 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLIOFDBM_01942 7.3e-126 folA 1.5.1.3 H dihydrofolate reductase
KLIOFDBM_01943 1.5e-97 ptpA 3.1.3.48 T low molecular weight
KLIOFDBM_01944 4.1e-110 vex2 V ABC transporter, ATP-binding protein
KLIOFDBM_01945 4.4e-209 vex1 V Efflux ABC transporter, permease protein
KLIOFDBM_01946 5.2e-219 vex3 V ABC transporter permease
KLIOFDBM_01947 3.5e-09 L HTH-like domain
KLIOFDBM_01948 0.0 G Glycosyl hydrolase family 20, domain 2
KLIOFDBM_01949 4.5e-219 GK ROK family
KLIOFDBM_01950 1.3e-243 G Bacterial extracellular solute-binding protein
KLIOFDBM_01951 6.3e-22 L Helix-turn-helix domain
KLIOFDBM_01952 4.8e-185 lacR K Transcriptional regulator, LacI family
KLIOFDBM_01953 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KLIOFDBM_01954 9.5e-267 lacS G Psort location CytoplasmicMembrane, score 10.00
KLIOFDBM_01955 7.9e-15 L Phage integrase family
KLIOFDBM_01956 1.3e-26 S PIN domain
KLIOFDBM_01957 2.4e-44 S Helix-turn-helix domain
KLIOFDBM_01958 0.0 XK27_00515 D Cell surface antigen C-terminus
KLIOFDBM_01959 1.3e-119 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
KLIOFDBM_01960 3.4e-94 K FR47-like protein
KLIOFDBM_01961 1.8e-281 S ATPases associated with a variety of cellular activities
KLIOFDBM_01962 6.8e-40
KLIOFDBM_01963 3.3e-101 parA D AAA domain
KLIOFDBM_01964 1.3e-81 S Transcription factor WhiB
KLIOFDBM_01965 4.7e-214 S Helix-turn-helix domain
KLIOFDBM_01966 5.6e-10 S Helix-turn-helix domain
KLIOFDBM_01968 6e-68
KLIOFDBM_01969 3.1e-234 L Phage integrase family
KLIOFDBM_01970 1.6e-80
KLIOFDBM_01971 3.9e-128
KLIOFDBM_01972 3.6e-20 S Protein of unknown function (DUF2599)
KLIOFDBM_01974 4.1e-245 L Phage integrase family
KLIOFDBM_01975 1.4e-35 G Glycosyl hydrolase family 20, domain 2
KLIOFDBM_01976 1.8e-59 G Glycosyl hydrolase family 20, domain 2
KLIOFDBM_01977 1.4e-140 G Glycosyl hydrolase family 20, domain 2
KLIOFDBM_01978 5.7e-65
KLIOFDBM_01979 1e-15 phnI 2.7.8.37 P Phosphonate
KLIOFDBM_01980 1.1e-61 yagW S Part of the ecpRABCDE operon, which encodes the E.coli common pilus (ECP). ECP is found in both commensal and pathogenic strains and plays a dual role in early-stage biofilm development and host cell recognition. Tip pilus adhesin, which is required for assembly of EcpA into fibers (By similarity)
KLIOFDBM_01981 4.5e-22 hscB O Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KLIOFDBM_01982 1.2e-27 modF 3.6.3.21, 3.6.3.34 P Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers
KLIOFDBM_01983 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
KLIOFDBM_01984 0.0 dnaK O Heat shock 70 kDa protein
KLIOFDBM_01985 5.2e-58 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLIOFDBM_01986 9.4e-157 dnaJ1 O DnaJ molecular chaperone homology domain
KLIOFDBM_01987 2.7e-103 hspR K transcriptional regulator, MerR family
KLIOFDBM_01988 3.1e-17 F Psort location CytoplasmicMembrane, score 10.00
KLIOFDBM_01989 3.3e-114 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
KLIOFDBM_01990 2.8e-140 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
KLIOFDBM_01991 6.7e-127 S HAD hydrolase, family IA, variant 3
KLIOFDBM_01992 1e-133 dedA S SNARE associated Golgi protein
KLIOFDBM_01993 6e-122 cpaE D bacterial-type flagellum organization
KLIOFDBM_01994 5.5e-189 cpaF U Type II IV secretion system protein
KLIOFDBM_01995 9.8e-74 U Type ii secretion system
KLIOFDBM_01996 5.8e-115 gspF NU Type II secretion system (T2SS), protein F
KLIOFDBM_01997 1.1e-41 S Protein of unknown function (DUF4244)
KLIOFDBM_01998 1.4e-57 U TadE-like protein
KLIOFDBM_01999 6.5e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
KLIOFDBM_02000 1.1e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
KLIOFDBM_02001 3.5e-95 K Bacterial regulatory proteins, tetR family
KLIOFDBM_02002 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
KLIOFDBM_02003 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLIOFDBM_02004 8.6e-31 S ATPase domain predominantly from Archaea
KLIOFDBM_02005 6.6e-197 3.4.22.70 M Sortase family
KLIOFDBM_02006 4.8e-69 V Abi-like protein
KLIOFDBM_02007 3.6e-193 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KLIOFDBM_02008 1.3e-134 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KLIOFDBM_02009 1.8e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
KLIOFDBM_02010 2.9e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLIOFDBM_02011 2.5e-112
KLIOFDBM_02012 1.5e-174 L Domain of unknown function (DUF4862)
KLIOFDBM_02013 4.1e-168 2.7.1.2 GK ROK family
KLIOFDBM_02014 1.3e-125 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
KLIOFDBM_02015 3.7e-159 3.5.1.106 I carboxylic ester hydrolase activity
KLIOFDBM_02016 3.1e-300 E Bacterial extracellular solute-binding proteins, family 5 Middle
KLIOFDBM_02017 4.6e-153 oppB6 EP Binding-protein-dependent transport system inner membrane component
KLIOFDBM_02018 0.0 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
KLIOFDBM_02019 6.5e-148 oppF E ATPases associated with a variety of cellular activities
KLIOFDBM_02020 9.8e-180 nanL 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
KLIOFDBM_02021 4.6e-146 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KLIOFDBM_02022 3.5e-13 nagA 3.5.1.25 G Amidohydrolase family
KLIOFDBM_02023 0.0 nanI 3.2.1.18 GH33 G BNR repeat-like domain
KLIOFDBM_02024 1.2e-246 P Domain of unknown function (DUF4143)
KLIOFDBM_02025 9e-153 K FCD
KLIOFDBM_02026 6e-16 S Calcineurin-like phosphoesterase
KLIOFDBM_02027 8.8e-273 S Calcineurin-like phosphoesterase
KLIOFDBM_02028 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KLIOFDBM_02029 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KLIOFDBM_02030 1.6e-165 3.6.1.27 I PAP2 superfamily
KLIOFDBM_02031 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLIOFDBM_02032 4.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLIOFDBM_02033 3.9e-207 holB 2.7.7.7 L DNA polymerase III
KLIOFDBM_02034 3e-105 K helix_turn _helix lactose operon repressor
KLIOFDBM_02035 3.3e-37 ptsH G PTS HPr component phosphorylation site
KLIOFDBM_02036 3.9e-293 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLIOFDBM_02037 3.1e-104 S Phosphatidylethanolamine-binding protein
KLIOFDBM_02038 2.7e-310 pepD E Peptidase family C69
KLIOFDBM_02039 2.5e-286 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
KLIOFDBM_02040 6.7e-62 S Macrophage migration inhibitory factor (MIF)
KLIOFDBM_02041 8.4e-96 S GtrA-like protein
KLIOFDBM_02042 4.8e-247 EGP Major facilitator Superfamily
KLIOFDBM_02043 2.6e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
KLIOFDBM_02044 6.3e-118
KLIOFDBM_02045 1.4e-228 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KLIOFDBM_02046 2.2e-145 S Protein of unknown function (DUF805)
KLIOFDBM_02048 2.7e-293 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLIOFDBM_02051 2.7e-31 L Phage integrase, N-terminal SAM-like domain
KLIOFDBM_02052 1.9e-22 L Phage integrase, N-terminal SAM-like domain
KLIOFDBM_02054 0.0 efeU_1 P Iron permease FTR1 family
KLIOFDBM_02055 1.6e-99 tpd P Fe2+ transport protein
KLIOFDBM_02056 3.2e-231 S Predicted membrane protein (DUF2318)
KLIOFDBM_02057 6.5e-227 macB_2 V ABC transporter permease
KLIOFDBM_02058 2.1e-199 Z012_06715 V FtsX-like permease family
KLIOFDBM_02059 1.7e-145 macB V ABC transporter, ATP-binding protein
KLIOFDBM_02060 2.4e-61 S FMN_bind
KLIOFDBM_02061 7.1e-101 K Psort location Cytoplasmic, score 8.87
KLIOFDBM_02062 2.2e-304 pip S YhgE Pip domain protein
KLIOFDBM_02063 0.0 pip S YhgE Pip domain protein
KLIOFDBM_02064 5.1e-251 S Putative ABC-transporter type IV
KLIOFDBM_02065 2.2e-271 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLIOFDBM_02066 2.2e-17 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLIOFDBM_02068 6e-51 tnpA L Transposase
KLIOFDBM_02069 2.7e-10 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLIOFDBM_02070 1.9e-53 wecA 2.7.8.33, 2.7.8.35, 5.1.3.14 M Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55)
KLIOFDBM_02071 1.5e-25 tnpA L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)