ORF_ID e_value Gene_name EC_number CAZy COGs Description
MHPFIANA_00001 6.1e-282 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHPFIANA_00002 1e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHPFIANA_00003 6.3e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHPFIANA_00004 6.2e-90 S Protein of unknown function (DUF721)
MHPFIANA_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHPFIANA_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHPFIANA_00007 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
MHPFIANA_00008 6e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHPFIANA_00009 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHPFIANA_00013 3.1e-101 S Protein of unknown function DUF45
MHPFIANA_00014 5e-187 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MHPFIANA_00015 2.8e-241 ytfL P Transporter associated domain
MHPFIANA_00016 5.3e-119 cah 4.2.1.1 P Reversible hydration of carbon dioxide
MHPFIANA_00017 5e-181
MHPFIANA_00018 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MHPFIANA_00019 0.0 yjjP S Threonine/Serine exporter, ThrE
MHPFIANA_00020 9.4e-300 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPFIANA_00021 5.9e-205 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPFIANA_00022 1.4e-41 S Protein of unknown function (DUF3073)
MHPFIANA_00023 1.7e-63 I Sterol carrier protein
MHPFIANA_00024 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHPFIANA_00025 3.4e-35
MHPFIANA_00026 8.5e-129 gluP 3.4.21.105 S Rhomboid family
MHPFIANA_00027 1.9e-240 L ribosomal rna small subunit methyltransferase
MHPFIANA_00028 3.1e-57 crgA D Involved in cell division
MHPFIANA_00029 6.8e-142 S Bacterial protein of unknown function (DUF881)
MHPFIANA_00030 6.7e-209 srtA 3.4.22.70 M Sortase family
MHPFIANA_00031 9.3e-118 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
MHPFIANA_00032 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
MHPFIANA_00033 5.8e-177 T Protein tyrosine kinase
MHPFIANA_00034 3e-265 pbpA M penicillin-binding protein
MHPFIANA_00035 1.2e-251 rodA D Belongs to the SEDS family
MHPFIANA_00036 6.8e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
MHPFIANA_00037 5.2e-71 fhaB T Inner membrane component of T3SS, cytoplasmic domain
MHPFIANA_00038 1.2e-131 fhaA T Protein of unknown function (DUF2662)
MHPFIANA_00039 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
MHPFIANA_00040 3.3e-223 2.7.13.3 T Histidine kinase
MHPFIANA_00041 3.3e-95 K helix_turn_helix, Lux Regulon
MHPFIANA_00042 7.5e-197 pldB 3.1.1.5 I Serine aminopeptidase, S33
MHPFIANA_00043 8.8e-160 yicL EG EamA-like transporter family
MHPFIANA_00048 1.8e-22 2.7.13.3 T Histidine kinase
MHPFIANA_00049 2e-36 K helix_turn_helix, Lux Regulon
MHPFIANA_00050 3e-267 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHPFIANA_00051 4.2e-262 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
MHPFIANA_00052 0.0 cadA P E1-E2 ATPase
MHPFIANA_00053 7.9e-188 ansA 3.5.1.1 EJ Asparaginase
MHPFIANA_00054 3.1e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
MHPFIANA_00055 3e-169 htpX O Belongs to the peptidase M48B family
MHPFIANA_00057 7.2e-186 K Helix-turn-helix XRE-family like proteins
MHPFIANA_00058 1.8e-170 yddG EG EamA-like transporter family
MHPFIANA_00059 0.0 pip S YhgE Pip domain protein
MHPFIANA_00060 0.0 pip S YhgE Pip domain protein
MHPFIANA_00061 1.6e-205 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MHPFIANA_00062 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHPFIANA_00063 1.1e-297 clcA P Voltage gated chloride channel
MHPFIANA_00064 5.2e-152 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPFIANA_00065 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPFIANA_00066 1.4e-29 E Receptor family ligand binding region
MHPFIANA_00067 1.8e-198 K helix_turn _helix lactose operon repressor
MHPFIANA_00068 3.1e-297 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
MHPFIANA_00069 1.5e-115 S Protein of unknown function, DUF624
MHPFIANA_00070 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
MHPFIANA_00071 9.3e-218 G Bacterial extracellular solute-binding protein
MHPFIANA_00072 2.9e-162 amyD3 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_00073 1.6e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_00074 3.3e-270 scrT G Transporter major facilitator family protein
MHPFIANA_00075 3.5e-252 yhjE EGP Sugar (and other) transporter
MHPFIANA_00076 1.8e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHPFIANA_00077 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MHPFIANA_00078 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
MHPFIANA_00079 7e-38 G beta-mannosidase
MHPFIANA_00080 2.5e-189 K helix_turn _helix lactose operon repressor
MHPFIANA_00081 8.3e-12 S Protein of unknown function, DUF624
MHPFIANA_00082 5.4e-270 aroP E aromatic amino acid transport protein AroP K03293
MHPFIANA_00083 0.0 V FtsX-like permease family
MHPFIANA_00084 1.1e-225 P Sodium/hydrogen exchanger family
MHPFIANA_00085 1.3e-76 S Psort location Cytoplasmic, score 8.87
MHPFIANA_00086 5e-175 3.4.22.70 M Sortase family
MHPFIANA_00087 3.5e-137 Q von Willebrand factor (vWF) type A domain
MHPFIANA_00088 1.4e-177 M LPXTG cell wall anchor motif
MHPFIANA_00089 2.8e-80 S Psort location Cytoplasmic, score 8.87
MHPFIANA_00090 3.5e-280 cycA E Amino acid permease
MHPFIANA_00091 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MHPFIANA_00092 3.2e-127 thiF 2.7.7.73, 2.7.7.80 H ThiF family
MHPFIANA_00093 2.5e-26 thiS 2.8.1.10 H ThiS family
MHPFIANA_00094 1.4e-154 1.1.1.65 C Aldo/keto reductase family
MHPFIANA_00095 1.1e-57 ydgJ K helix_turn_helix multiple antibiotic resistance protein
MHPFIANA_00096 1.3e-284 lmrA1 V ABC transporter, ATP-binding protein
MHPFIANA_00097 6.5e-310 lmrA2 V ABC transporter transmembrane region
MHPFIANA_00098 1.5e-116 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHPFIANA_00099 2.6e-237 G MFS/sugar transport protein
MHPFIANA_00100 1.7e-294 efeU_1 P Iron permease FTR1 family
MHPFIANA_00101 4.1e-92 tpd P Fe2+ transport protein
MHPFIANA_00102 1.5e-231 S Predicted membrane protein (DUF2318)
MHPFIANA_00103 1.4e-219 macB_2 V ABC transporter permease
MHPFIANA_00105 7e-202 Z012_06715 V FtsX-like permease family
MHPFIANA_00106 9e-150 macB V ABC transporter, ATP-binding protein
MHPFIANA_00107 1.1e-61 S FMN_bind
MHPFIANA_00108 4.1e-89 K Psort location Cytoplasmic, score 8.87
MHPFIANA_00109 1.1e-274 pip S YhgE Pip domain protein
MHPFIANA_00110 0.0 pip S YhgE Pip domain protein
MHPFIANA_00111 1.6e-225 S Putative ABC-transporter type IV
MHPFIANA_00112 6e-38 nrdH O Glutaredoxin
MHPFIANA_00113 6.4e-265 M cell wall binding repeat
MHPFIANA_00115 7.3e-308 pepD E Peptidase family C69
MHPFIANA_00116 5.7e-194 XK27_01805 M Glycosyltransferase like family 2
MHPFIANA_00118 4.9e-108 icaR K Bacterial regulatory proteins, tetR family
MHPFIANA_00119 5.6e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHPFIANA_00120 4.5e-236 amt U Ammonium Transporter Family
MHPFIANA_00121 1e-54 glnB K Nitrogen regulatory protein P-II
MHPFIANA_00122 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
MHPFIANA_00123 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MHPFIANA_00124 7.8e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
MHPFIANA_00125 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MHPFIANA_00126 1e-27 S granule-associated protein
MHPFIANA_00127 0.0 ubiB S ABC1 family
MHPFIANA_00128 1.4e-192 K Periplasmic binding protein domain
MHPFIANA_00129 2.5e-242 G Bacterial extracellular solute-binding protein
MHPFIANA_00130 3.3e-07 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_00131 3.1e-167 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_00132 9.3e-147 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_00133 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
MHPFIANA_00134 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
MHPFIANA_00135 0.0 G Bacterial Ig-like domain (group 4)
MHPFIANA_00136 3.2e-208 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MHPFIANA_00137 6e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHPFIANA_00138 3.9e-91
MHPFIANA_00139 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
MHPFIANA_00140 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MHPFIANA_00142 5.5e-141 cpaE D bacterial-type flagellum organization
MHPFIANA_00143 1.6e-185 cpaF U Type II IV secretion system protein
MHPFIANA_00144 1.2e-132 U Type ii secretion system
MHPFIANA_00145 1.5e-86 gspF NU Type II secretion system (T2SS), protein F
MHPFIANA_00146 1.3e-42 S Protein of unknown function (DUF4244)
MHPFIANA_00147 5.1e-60 U TadE-like protein
MHPFIANA_00148 3e-55 S TIGRFAM helicase secretion neighborhood TadE-like protein
MHPFIANA_00149 4.9e-218 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
MHPFIANA_00150 3.5e-193 S Psort location CytoplasmicMembrane, score
MHPFIANA_00151 1.1e-96 K Bacterial regulatory proteins, tetR family
MHPFIANA_00152 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
MHPFIANA_00153 4.5e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHPFIANA_00154 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MHPFIANA_00155 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
MHPFIANA_00156 1.8e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHPFIANA_00157 2.7e-48 yitI S Acetyltransferase (GNAT) domain
MHPFIANA_00158 2.4e-115
MHPFIANA_00159 1.4e-300 S Calcineurin-like phosphoesterase
MHPFIANA_00160 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MHPFIANA_00161 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
MHPFIANA_00162 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
MHPFIANA_00163 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
MHPFIANA_00164 1.1e-195 K helix_turn _helix lactose operon repressor
MHPFIANA_00165 2e-207 abf G Glycosyl hydrolases family 43
MHPFIANA_00166 8.2e-246 G Bacterial extracellular solute-binding protein
MHPFIANA_00167 9.1e-170 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_00168 1.9e-156 U Binding-protein-dependent transport system inner membrane component
MHPFIANA_00169 0.0 S Beta-L-arabinofuranosidase, GH127
MHPFIANA_00170 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MHPFIANA_00171 1.1e-214 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
MHPFIANA_00172 3.1e-228 glf 5.4.99.9 M UDP-galactopyranose mutase
MHPFIANA_00173 3e-195 3.6.1.27 I PAP2 superfamily
MHPFIANA_00174 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHPFIANA_00175 4.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHPFIANA_00176 1.2e-192 holB 2.7.7.7 L DNA polymerase III
MHPFIANA_00177 5.4e-184 K helix_turn _helix lactose operon repressor
MHPFIANA_00178 6e-39 ptsH G PTS HPr component phosphorylation site
MHPFIANA_00179 1e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHPFIANA_00180 1.1e-106 S Phosphatidylethanolamine-binding protein
MHPFIANA_00181 0.0 pepD E Peptidase family C69
MHPFIANA_00182 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
MHPFIANA_00183 6.7e-62 S Macrophage migration inhibitory factor (MIF)
MHPFIANA_00184 2.4e-95 S GtrA-like protein
MHPFIANA_00185 3.6e-263 EGP Major facilitator Superfamily
MHPFIANA_00186 1.7e-122 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
MHPFIANA_00187 7e-184
MHPFIANA_00188 7.7e-98 S Protein of unknown function (DUF805)
MHPFIANA_00189 5.5e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHPFIANA_00192 1.5e-278 S Calcineurin-like phosphoesterase
MHPFIANA_00193 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
MHPFIANA_00194 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHPFIANA_00195 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MHPFIANA_00196 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
MHPFIANA_00197 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHPFIANA_00198 1.2e-176 plsC2 2.3.1.51 I Phosphate acyltransferases
MHPFIANA_00199 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
MHPFIANA_00200 1.2e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MHPFIANA_00201 1.7e-218 P Bacterial extracellular solute-binding protein
MHPFIANA_00202 2e-156 U Binding-protein-dependent transport system inner membrane component
MHPFIANA_00203 6.2e-141 U Binding-protein-dependent transport system inner membrane component
MHPFIANA_00204 2.6e-214 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHPFIANA_00205 4.3e-179 S CAAX protease self-immunity
MHPFIANA_00206 1.7e-137 M Mechanosensitive ion channel
MHPFIANA_00207 5.3e-231 MA20_36090 S Psort location Cytoplasmic, score 8.87
MHPFIANA_00208 2.4e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
MHPFIANA_00209 1.3e-125 K Bacterial regulatory proteins, tetR family
MHPFIANA_00210 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
MHPFIANA_00211 5.2e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
MHPFIANA_00213 6e-228 gnuT EG GntP family permease
MHPFIANA_00214 2.1e-83 gntK 2.7.1.12 F Shikimate kinase
MHPFIANA_00215 2.3e-120 gntR K FCD
MHPFIANA_00216 3.5e-228 yxiO S Vacuole effluxer Atg22 like
MHPFIANA_00217 0.0 S Psort location Cytoplasmic, score 8.87
MHPFIANA_00218 8.4e-30 rpmB J Ribosomal L28 family
MHPFIANA_00219 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
MHPFIANA_00220 2.4e-91 rsmD 2.1.1.171 L Conserved hypothetical protein 95
MHPFIANA_00221 1.5e-90 K helix_turn_helix, arabinose operon control protein
MHPFIANA_00222 3.2e-138 uhpT EGP Major facilitator Superfamily
MHPFIANA_00223 2.1e-148 I alpha/beta hydrolase fold
MHPFIANA_00224 1.6e-145 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MHPFIANA_00225 3.6e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHPFIANA_00226 1.8e-34 CP_0960 S Belongs to the UPF0109 family
MHPFIANA_00227 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MHPFIANA_00228 2e-178 S Endonuclease/Exonuclease/phosphatase family
MHPFIANA_00229 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHPFIANA_00230 3.9e-301 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPFIANA_00231 1.1e-152 guaA1 6.3.5.2 F Peptidase C26
MHPFIANA_00232 0.0 yjjK S ABC transporter
MHPFIANA_00233 6.4e-96
MHPFIANA_00234 5.7e-92 ilvN 2.2.1.6 E ACT domain
MHPFIANA_00235 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
MHPFIANA_00236 7.5e-136 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHPFIANA_00237 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MHPFIANA_00238 1.8e-113 yceD S Uncharacterized ACR, COG1399
MHPFIANA_00239 8.5e-134
MHPFIANA_00240 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHPFIANA_00241 7.2e-58 S Protein of unknown function (DUF3039)
MHPFIANA_00242 7.3e-194 yghZ C Aldo/keto reductase family
MHPFIANA_00243 9.2e-77 soxR K MerR, DNA binding
MHPFIANA_00244 1.8e-119 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHPFIANA_00245 3e-139 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MHPFIANA_00246 1.7e-251 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHPFIANA_00247 1.7e-243 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
MHPFIANA_00248 1.8e-221 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
MHPFIANA_00251 5.4e-181 S Auxin Efflux Carrier
MHPFIANA_00252 0.0 pgi 5.3.1.9 G Belongs to the GPI family
MHPFIANA_00253 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHPFIANA_00254 1.1e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MHPFIANA_00255 7.2e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPFIANA_00256 6.6e-128 V ATPases associated with a variety of cellular activities
MHPFIANA_00257 2.5e-270 V Efflux ABC transporter, permease protein
MHPFIANA_00258 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
MHPFIANA_00259 3.1e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
MHPFIANA_00260 1.9e-308 rne 3.1.26.12 J Ribonuclease E/G family
MHPFIANA_00261 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
MHPFIANA_00262 2.6e-39 rpmA J Ribosomal L27 protein
MHPFIANA_00263 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHPFIANA_00264 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHPFIANA_00265 4.8e-232 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
MHPFIANA_00267 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHPFIANA_00268 2.9e-129 nusG K Participates in transcription elongation, termination and antitermination
MHPFIANA_00269 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHPFIANA_00270 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHPFIANA_00271 5.9e-143 QT PucR C-terminal helix-turn-helix domain
MHPFIANA_00272 0.0
MHPFIANA_00273 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
MHPFIANA_00274 2.1e-79 bioY S BioY family
MHPFIANA_00275 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
MHPFIANA_00276 0.0 pccB I Carboxyl transferase domain
MHPFIANA_00277 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
MHPFIANA_00279 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHPFIANA_00280 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
MHPFIANA_00282 2.4e-116
MHPFIANA_00283 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHPFIANA_00284 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MHPFIANA_00285 1.7e-91 lemA S LemA family
MHPFIANA_00286 0.0 S Predicted membrane protein (DUF2207)
MHPFIANA_00287 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
MHPFIANA_00288 7e-297 yegQ O Peptidase family U32 C-terminal domain
MHPFIANA_00289 4.5e-183 yfiH Q Multi-copper polyphenol oxidoreductase laccase
MHPFIANA_00290 2.5e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHPFIANA_00291 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MHPFIANA_00292 1.3e-58 D nuclear chromosome segregation
MHPFIANA_00293 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
MHPFIANA_00294 2.8e-210 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MHPFIANA_00295 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MHPFIANA_00296 5.2e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHPFIANA_00297 2.4e-219 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MHPFIANA_00298 3.4e-129 KT Transcriptional regulatory protein, C terminal
MHPFIANA_00299 7.2e-198 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
MHPFIANA_00300 1.5e-164 pstC P probably responsible for the translocation of the substrate across the membrane
MHPFIANA_00301 5.2e-168 pstA P Phosphate transport system permease
MHPFIANA_00302 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHPFIANA_00303 4.3e-145 P Zinc-uptake complex component A periplasmic
MHPFIANA_00304 1.3e-246 pbuO S Permease family
MHPFIANA_00305 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHPFIANA_00306 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHPFIANA_00307 3.6e-175 T Forkhead associated domain
MHPFIANA_00308 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
MHPFIANA_00309 2.4e-35
MHPFIANA_00310 4e-90 flgA NO SAF
MHPFIANA_00311 6.1e-30 fmdB S Putative regulatory protein
MHPFIANA_00312 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
MHPFIANA_00313 2.9e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
MHPFIANA_00314 1.6e-147
MHPFIANA_00315 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHPFIANA_00319 5.5e-25 rpmG J Ribosomal protein L33
MHPFIANA_00320 1.9e-204 murB 1.3.1.98 M Cell wall formation
MHPFIANA_00321 2.8e-266 E aromatic amino acid transport protein AroP K03293
MHPFIANA_00322 8.3e-59 fdxA C 4Fe-4S binding domain
MHPFIANA_00323 4.6e-208 dapC E Aminotransferase class I and II
MHPFIANA_00324 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
MHPFIANA_00325 1.1e-181 EP Binding-protein-dependent transport system inner membrane component
MHPFIANA_00326 5.1e-141 EP Binding-protein-dependent transport system inner membrane component
MHPFIANA_00327 1.9e-155 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
MHPFIANA_00328 7.4e-152 dppF E ABC transporter
MHPFIANA_00329 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MHPFIANA_00331 0.0 G Psort location Cytoplasmic, score 8.87
MHPFIANA_00332 4.1e-233 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
MHPFIANA_00333 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
MHPFIANA_00334 1.3e-295 CE10 I Belongs to the type-B carboxylesterase lipase family
MHPFIANA_00336 4.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHPFIANA_00337 1e-251 M Bacterial capsule synthesis protein PGA_cap
MHPFIANA_00338 1.2e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPFIANA_00339 2.1e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
MHPFIANA_00340 3.1e-122
MHPFIANA_00341 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MHPFIANA_00342 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHPFIANA_00343 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
MHPFIANA_00344 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MHPFIANA_00345 1.4e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPFIANA_00346 2e-216 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
MHPFIANA_00347 4.2e-239 EGP Major facilitator Superfamily
MHPFIANA_00348 3.3e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
MHPFIANA_00349 1.5e-183 rhaR_1 K helix_turn_helix, arabinose operon control protein
MHPFIANA_00350 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MHPFIANA_00351 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
MHPFIANA_00352 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHPFIANA_00353 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
MHPFIANA_00354 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHPFIANA_00355 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHPFIANA_00356 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHPFIANA_00357 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHPFIANA_00358 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHPFIANA_00359 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHPFIANA_00360 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
MHPFIANA_00361 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHPFIANA_00362 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHPFIANA_00363 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHPFIANA_00364 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHPFIANA_00365 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHPFIANA_00366 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHPFIANA_00367 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHPFIANA_00368 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHPFIANA_00369 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHPFIANA_00370 3.4e-25 rpmD J Ribosomal protein L30p/L7e
MHPFIANA_00371 9.8e-74 rplO J binds to the 23S rRNA
MHPFIANA_00372 3.8e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHPFIANA_00373 5.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHPFIANA_00374 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHPFIANA_00375 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MHPFIANA_00376 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHPFIANA_00377 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHPFIANA_00378 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPFIANA_00379 1.3e-66 rplQ J Ribosomal protein L17
MHPFIANA_00380 4.4e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHPFIANA_00381 8.1e-43 gcs2 S A circularly permuted ATPgrasp
MHPFIANA_00382 1.5e-45 E Transglutaminase/protease-like homologues
MHPFIANA_00384 1.2e-102
MHPFIANA_00385 6.1e-191 nusA K Participates in both transcription termination and antitermination
MHPFIANA_00386 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHPFIANA_00387 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHPFIANA_00388 5.1e-188 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHPFIANA_00389 2e-217 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
MHPFIANA_00390 2.4e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHPFIANA_00391 3.8e-108
MHPFIANA_00393 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHPFIANA_00394 3e-210 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPFIANA_00395 3e-251 T GHKL domain
MHPFIANA_00396 7.2e-152 T LytTr DNA-binding domain
MHPFIANA_00397 3.6e-07 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MHPFIANA_00398 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
MHPFIANA_00399 0.0 crr G pts system, glucose-specific IIABC component
MHPFIANA_00400 2.8e-157 arbG K CAT RNA binding domain
MHPFIANA_00401 9.8e-200 I Diacylglycerol kinase catalytic domain
MHPFIANA_00402 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHPFIANA_00404 4.6e-188 yegU O ADP-ribosylglycohydrolase
MHPFIANA_00405 8.3e-190 yegV G pfkB family carbohydrate kinase
MHPFIANA_00406 4.5e-269 U Permease for cytosine/purines, uracil, thiamine, allantoin
MHPFIANA_00407 1.5e-103 Q Isochorismatase family
MHPFIANA_00408 2.3e-214 S Choline/ethanolamine kinase
MHPFIANA_00409 2.5e-275 eat E Amino acid permease
MHPFIANA_00410 5.3e-264 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
MHPFIANA_00411 1.9e-141 yidP K UTRA
MHPFIANA_00412 1.3e-120 degU K helix_turn_helix, Lux Regulon
MHPFIANA_00413 4.2e-249 tcsS3 KT PspC domain
MHPFIANA_00414 4.9e-146 pspC KT PspC domain
MHPFIANA_00415 1.1e-90
MHPFIANA_00416 6.7e-116 S Protein of unknown function (DUF4125)
MHPFIANA_00417 0.0 S Domain of unknown function (DUF4037)
MHPFIANA_00418 1.3e-210 araJ EGP Major facilitator Superfamily
MHPFIANA_00420 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MHPFIANA_00421 3.9e-190 K helix_turn _helix lactose operon repressor
MHPFIANA_00422 6.3e-249 G Psort location CytoplasmicMembrane, score 10.00
MHPFIANA_00423 4.1e-99 S Serine aminopeptidase, S33
MHPFIANA_00424 3.5e-132 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MHPFIANA_00425 2.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHPFIANA_00426 0.0 4.2.1.53 S MCRA family
MHPFIANA_00427 1.3e-88 phoU P Plays a role in the regulation of phosphate uptake
MHPFIANA_00428 1.4e-215 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHPFIANA_00429 6.2e-41
MHPFIANA_00430 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHPFIANA_00431 1.9e-164 usp 3.5.1.28 CBM50 S CHAP domain
MHPFIANA_00432 1.3e-79 M NlpC/P60 family
MHPFIANA_00433 1.3e-190 T Universal stress protein family
MHPFIANA_00434 7.7e-73 attW O OsmC-like protein
MHPFIANA_00435 3.8e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHPFIANA_00436 6.4e-130 folA 1.5.1.3 H dihydrofolate reductase
MHPFIANA_00437 3.6e-85 ptpA 3.1.3.48 T low molecular weight
MHPFIANA_00439 9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MHPFIANA_00440 2.2e-170 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHPFIANA_00444 5.8e-272 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
MHPFIANA_00445 7.2e-121 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
MHPFIANA_00446 2e-161
MHPFIANA_00447 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
MHPFIANA_00448 2e-277 pelF GT4 M Domain of unknown function (DUF3492)
MHPFIANA_00449 3.5e-280 pelG S Putative exopolysaccharide Exporter (EPS-E)
MHPFIANA_00450 7.2e-309 cotH M CotH kinase protein
MHPFIANA_00451 5.3e-158 P VTC domain
MHPFIANA_00452 2.2e-111 S Domain of unknown function (DUF4956)
MHPFIANA_00453 0.0 yliE T Putative diguanylate phosphodiesterase
MHPFIANA_00454 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
MHPFIANA_00455 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
MHPFIANA_00456 1e-234 S AI-2E family transporter
MHPFIANA_00457 6.3e-232 epsG M Glycosyl transferase family 21
MHPFIANA_00458 1.1e-232 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
MHPFIANA_00459 3.3e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHPFIANA_00460 3.9e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MHPFIANA_00461 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHPFIANA_00462 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
MHPFIANA_00463 6.9e-156 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MHPFIANA_00464 4.1e-273 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHPFIANA_00465 2.3e-93 S Protein of unknown function (DUF3180)
MHPFIANA_00466 1.3e-168 tesB I Thioesterase-like superfamily
MHPFIANA_00467 0.0 yjjK S ATP-binding cassette protein, ChvD family
MHPFIANA_00468 2.2e-181 V Beta-lactamase
MHPFIANA_00469 2.5e-74 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MHPFIANA_00470 1.5e-81 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
MHPFIANA_00471 3.5e-183 L PFAM Integrase catalytic
MHPFIANA_00472 0.0 O Highly conserved protein containing a thioredoxin domain
MHPFIANA_00473 2.4e-116 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
MHPFIANA_00474 1.3e-16 ydcZ S Putative inner membrane exporter, YdcZ
MHPFIANA_00475 4.5e-107 S Membrane
MHPFIANA_00476 3.6e-266 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
MHPFIANA_00477 1.3e-248 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
MHPFIANA_00478 6.6e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MHPFIANA_00479 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
MHPFIANA_00480 7.2e-189 K Bacterial regulatory proteins, lacI family
MHPFIANA_00481 2.4e-242 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
MHPFIANA_00482 1.5e-186 MA20_14025 U Binding-protein-dependent transport system inner membrane component
MHPFIANA_00483 2.4e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_00484 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MHPFIANA_00485 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
MHPFIANA_00486 6.3e-08 CE10 I Belongs to the type-B carboxylesterase lipase family
MHPFIANA_00487 2.8e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MHPFIANA_00488 4.5e-288 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
MHPFIANA_00489 5.7e-225 xylR GK ROK family
MHPFIANA_00491 1.5e-35 rpmE J Binds the 23S rRNA
MHPFIANA_00492 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHPFIANA_00493 4.7e-171 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHPFIANA_00494 7.8e-219 livK E Receptor family ligand binding region
MHPFIANA_00495 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
MHPFIANA_00496 1.5e-195 livM U Belongs to the binding-protein-dependent transport system permease family
MHPFIANA_00497 4.8e-151 E Branched-chain amino acid ATP-binding cassette transporter
MHPFIANA_00498 1.9e-124 livF E ATPases associated with a variety of cellular activities
MHPFIANA_00499 1.9e-113 ywlC 2.7.7.87 J Belongs to the SUA5 family
MHPFIANA_00500 1.7e-194 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
MHPFIANA_00501 2.2e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MHPFIANA_00502 3.1e-121 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MHPFIANA_00503 5e-162 supH S Sucrose-6F-phosphate phosphohydrolase
MHPFIANA_00504 1e-270 recD2 3.6.4.12 L PIF1-like helicase
MHPFIANA_00505 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHPFIANA_00506 1.4e-98 L Single-strand binding protein family
MHPFIANA_00507 0.0 pepO 3.4.24.71 O Peptidase family M13
MHPFIANA_00508 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
MHPFIANA_00509 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
MHPFIANA_00510 5.8e-143 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
MHPFIANA_00511 1.2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHPFIANA_00512 3.2e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHPFIANA_00513 2.3e-168 ftsE D Cell division ATP-binding protein FtsE
MHPFIANA_00514 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
MHPFIANA_00515 8.9e-150 usp 3.5.1.28 CBM50 D CHAP domain protein
MHPFIANA_00516 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MHPFIANA_00517 3e-157 pknD ET ABC transporter, substrate-binding protein, family 3
MHPFIANA_00518 8.9e-32 pknD ET ABC transporter, substrate-binding protein, family 3
MHPFIANA_00519 1.2e-150 pknD ET ABC transporter, substrate-binding protein, family 3
MHPFIANA_00520 2.2e-142 yecS E Binding-protein-dependent transport system inner membrane component
MHPFIANA_00521 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
MHPFIANA_00522 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHPFIANA_00523 5.5e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
MHPFIANA_00524 3.4e-228 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MHPFIANA_00525 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MHPFIANA_00526 7.2e-272 G Bacterial extracellular solute-binding protein
MHPFIANA_00527 2.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MHPFIANA_00528 2e-241 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHPFIANA_00529 1e-293 E ABC transporter, substrate-binding protein, family 5
MHPFIANA_00530 2.2e-166 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_00531 1.2e-139 EP Binding-protein-dependent transport system inner membrane component
MHPFIANA_00532 1.4e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
MHPFIANA_00533 1.3e-137 sapF E ATPases associated with a variety of cellular activities
MHPFIANA_00534 1.3e-190 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
MHPFIANA_00535 1e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MHPFIANA_00536 0.0 macB_2 V ATPases associated with a variety of cellular activities
MHPFIANA_00537 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MHPFIANA_00538 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHPFIANA_00539 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHPFIANA_00540 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
MHPFIANA_00541 2e-307 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHPFIANA_00542 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHPFIANA_00543 2e-214 ybiR P Citrate transporter
MHPFIANA_00545 7.5e-175 ydcZ S Putative inner membrane exporter, YdcZ
MHPFIANA_00547 0.0 tetP J Elongation factor G, domain IV
MHPFIANA_00551 1e-113 K acetyltransferase
MHPFIANA_00552 5.2e-54 papP E Binding-protein-dependent transport system inner membrane component
MHPFIANA_00553 3.6e-120 E Binding-protein-dependent transport system inner membrane component
MHPFIANA_00554 1.5e-152 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
MHPFIANA_00555 9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
MHPFIANA_00556 1.4e-200 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHPFIANA_00557 3.4e-155 metQ M NLPA lipoprotein
MHPFIANA_00558 6.5e-193 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHPFIANA_00559 4.9e-98 metI P Psort location CytoplasmicMembrane, score 9.99
MHPFIANA_00560 5.3e-220 mtnE 2.6.1.83 E Aminotransferase class I and II
MHPFIANA_00561 3.2e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MHPFIANA_00562 4.1e-14 P Belongs to the ABC transporter superfamily
MHPFIANA_00563 1.4e-43 XAC3035 O Glutaredoxin
MHPFIANA_00564 3.1e-127 XK27_08050 O prohibitin homologues
MHPFIANA_00565 2.6e-14 S Domain of unknown function (DUF4143)
MHPFIANA_00566 7.4e-75
MHPFIANA_00567 9.6e-135 V ATPases associated with a variety of cellular activities
MHPFIANA_00568 4.4e-147 M Conserved repeat domain
MHPFIANA_00569 6.8e-257 macB_8 V MacB-like periplasmic core domain
MHPFIANA_00570 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHPFIANA_00571 1.2e-183 adh3 C Zinc-binding dehydrogenase
MHPFIANA_00572 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHPFIANA_00573 4.9e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHPFIANA_00574 8.8e-89 zur P Belongs to the Fur family
MHPFIANA_00575 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MHPFIANA_00576 9.4e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
MHPFIANA_00577 2e-188 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
MHPFIANA_00578 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
MHPFIANA_00579 1.1e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
MHPFIANA_00580 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MHPFIANA_00581 5.6e-248 EGP Major facilitator Superfamily
MHPFIANA_00582 2.8e-235 purD 6.3.4.13 F Belongs to the GARS family
MHPFIANA_00583 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MHPFIANA_00584 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHPFIANA_00585 1.7e-309 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
MHPFIANA_00586 5.4e-36
MHPFIANA_00587 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
MHPFIANA_00588 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MHPFIANA_00589 4.6e-230 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHPFIANA_00590 6.5e-226 M Glycosyl transferase 4-like domain
MHPFIANA_00591 1.5e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
MHPFIANA_00593 8.9e-187 yocS S SBF-like CPA transporter family (DUF4137)
MHPFIANA_00595 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHPFIANA_00596 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHPFIANA_00597 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHPFIANA_00598 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHPFIANA_00599 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHPFIANA_00600 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHPFIANA_00601 1.1e-239 carA 6.3.5.5 F Belongs to the CarA family
MHPFIANA_00602 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
MHPFIANA_00603 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MHPFIANA_00604 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
MHPFIANA_00606 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
MHPFIANA_00607 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHPFIANA_00608 1e-226 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHPFIANA_00609 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHPFIANA_00610 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MHPFIANA_00611 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHPFIANA_00612 1.6e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
MHPFIANA_00613 1.3e-282 arc O AAA ATPase forming ring-shaped complexes
MHPFIANA_00614 3.5e-302 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
MHPFIANA_00615 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
MHPFIANA_00616 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
MHPFIANA_00617 6.7e-281 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
MHPFIANA_00618 9.7e-141 C FMN binding
MHPFIANA_00619 1.8e-57
MHPFIANA_00620 1.4e-41 hup L Belongs to the bacterial histone-like protein family
MHPFIANA_00621 0.0 S Lysylphosphatidylglycerol synthase TM region
MHPFIANA_00622 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
MHPFIANA_00623 1.6e-277 S PGAP1-like protein
MHPFIANA_00624 1.3e-62
MHPFIANA_00625 5e-182 S von Willebrand factor (vWF) type A domain
MHPFIANA_00626 4.7e-191 S von Willebrand factor (vWF) type A domain
MHPFIANA_00627 1.4e-90
MHPFIANA_00628 1.2e-174 S Protein of unknown function DUF58
MHPFIANA_00629 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
MHPFIANA_00630 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHPFIANA_00631 8.5e-77 S LytR cell envelope-related transcriptional attenuator
MHPFIANA_00632 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHPFIANA_00634 1.3e-124
MHPFIANA_00635 6.8e-133 KT Response regulator receiver domain protein
MHPFIANA_00636 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHPFIANA_00637 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
MHPFIANA_00638 1.2e-182 S Protein of unknown function (DUF3027)
MHPFIANA_00639 4.6e-188 uspA T Belongs to the universal stress protein A family
MHPFIANA_00640 0.0 clpC O ATPase family associated with various cellular activities (AAA)
MHPFIANA_00641 1.3e-254 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
MHPFIANA_00642 1.1e-284 purR QT Purine catabolism regulatory protein-like family
MHPFIANA_00643 5e-246 proP EGP Sugar (and other) transporter
MHPFIANA_00644 1.6e-140 3.5.2.10 S Creatinine amidohydrolase
MHPFIANA_00645 7.4e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
MHPFIANA_00646 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
MHPFIANA_00647 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MHPFIANA_00648 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
MHPFIANA_00649 3.3e-138 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
MHPFIANA_00650 1.4e-136 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
MHPFIANA_00651 6.8e-153 gluB ET Belongs to the bacterial solute-binding protein 3 family
MHPFIANA_00652 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
MHPFIANA_00653 1.7e-199 gluD E Binding-protein-dependent transport system inner membrane component
MHPFIANA_00654 4.3e-191 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
MHPFIANA_00655 0.0 L DEAD DEAH box helicase
MHPFIANA_00656 1.4e-251 rarA L Recombination factor protein RarA
MHPFIANA_00657 4.8e-134 KT Transcriptional regulatory protein, C terminal
MHPFIANA_00658 2.4e-287 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MHPFIANA_00659 0.0 lpqB S Lipoprotein LpqB beta-propeller domain
MHPFIANA_00660 2.4e-165 G Periplasmic binding protein domain
MHPFIANA_00661 6e-288 ytfR 3.6.3.17 G ATPases associated with a variety of cellular activities
MHPFIANA_00662 1.5e-181 ytfT U Branched-chain amino acid transport system / permease component
MHPFIANA_00663 1.6e-172 yjfF U Branched-chain amino acid transport system / permease component
MHPFIANA_00664 1.5e-251 EGP Major facilitator Superfamily
MHPFIANA_00665 2.3e-311 E ABC transporter, substrate-binding protein, family 5
MHPFIANA_00666 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHPFIANA_00667 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHPFIANA_00668 2.3e-240 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHPFIANA_00671 7.3e-245 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MHPFIANA_00672 4.8e-117 safC S O-methyltransferase
MHPFIANA_00673 1.5e-177 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
MHPFIANA_00674 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
MHPFIANA_00675 2.7e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
MHPFIANA_00676 1e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
MHPFIANA_00677 1.2e-82 yraN L Belongs to the UPF0102 family
MHPFIANA_00678 2.1e-165 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MHPFIANA_00679 5.9e-252 metY 2.5.1.49 E Aminotransferase class-V
MHPFIANA_00680 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
MHPFIANA_00681 5.1e-306 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
MHPFIANA_00682 4.5e-149 P Cobalt transport protein
MHPFIANA_00683 8.2e-193 K helix_turn_helix ASNC type
MHPFIANA_00684 5.1e-142 V ABC transporter, ATP-binding protein
MHPFIANA_00685 0.0 MV MacB-like periplasmic core domain
MHPFIANA_00686 1.9e-130 K helix_turn_helix, Lux Regulon
MHPFIANA_00687 0.0 tcsS2 T Histidine kinase
MHPFIANA_00688 5.8e-263 pip 3.4.11.5 S alpha/beta hydrolase fold
MHPFIANA_00689 1.6e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHPFIANA_00690 3.9e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHPFIANA_00691 1.9e-15 yccF S Inner membrane component domain
MHPFIANA_00692 5.9e-12
MHPFIANA_00693 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
MHPFIANA_00694 7e-85 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MHPFIANA_00695 1e-94
MHPFIANA_00696 1.1e-165 MA20_14895 S Conserved hypothetical protein 698
MHPFIANA_00697 2.1e-185 C Na H antiporter family protein
MHPFIANA_00698 6.5e-157 korD 1.2.7.3 C Domain of unknown function (DUF362)
MHPFIANA_00699 4.9e-79 2.7.1.48 F uridine kinase
MHPFIANA_00700 8.5e-70 S ECF transporter, substrate-specific component
MHPFIANA_00701 1.3e-143 S Sulfite exporter TauE/SafE
MHPFIANA_00702 1.5e-135 K helix_turn_helix, arabinose operon control protein
MHPFIANA_00703 1.4e-155 3.1.3.73 G Phosphoglycerate mutase family
MHPFIANA_00704 2.9e-227 rutG F Permease family
MHPFIANA_00705 2.1e-126 S Enoyl-(Acyl carrier protein) reductase
MHPFIANA_00706 6e-275 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
MHPFIANA_00707 1.8e-134 ybbM V Uncharacterised protein family (UPF0014)
MHPFIANA_00708 3.2e-142 ybbL V ATPases associated with a variety of cellular activities
MHPFIANA_00709 7.7e-242 S Putative esterase
MHPFIANA_00710 0.0 lysX S Uncharacterised conserved protein (DUF2156)
MHPFIANA_00711 2.6e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHPFIANA_00712 5.3e-147 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPFIANA_00713 8.2e-237 patB 4.4.1.8 E Aminotransferase, class I II
MHPFIANA_00714 3.6e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHPFIANA_00715 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
MHPFIANA_00716 2.9e-145 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
MHPFIANA_00717 1.8e-81 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHPFIANA_00718 1.3e-87 M Protein of unknown function (DUF3737)
MHPFIANA_00719 3.9e-142 azlC E AzlC protein
MHPFIANA_00720 1e-51 azlD E Branched-chain amino acid transport protein (AzlD)
MHPFIANA_00721 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
MHPFIANA_00722 6.2e-40 ybdD S Selenoprotein, putative
MHPFIANA_00723 4e-178 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
MHPFIANA_00724 0.0 S Uncharacterised protein family (UPF0182)
MHPFIANA_00725 3.6e-99 2.3.1.183 M Acetyltransferase (GNAT) domain
MHPFIANA_00726 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHPFIANA_00727 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHPFIANA_00728 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHPFIANA_00729 2e-71 divIC D Septum formation initiator
MHPFIANA_00730 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
MHPFIANA_00731 4.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MHPFIANA_00733 1.9e-71 P Major Facilitator Superfamily
MHPFIANA_00734 1.8e-91
MHPFIANA_00735 6.5e-284 sdaA 4.3.1.17 E Serine dehydratase alpha chain
MHPFIANA_00736 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
MHPFIANA_00737 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHPFIANA_00738 1e-143 yplQ S Haemolysin-III related
MHPFIANA_00739 6e-277 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHPFIANA_00740 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MHPFIANA_00741 0.0 D FtsK/SpoIIIE family
MHPFIANA_00742 1.9e-164 K Cell envelope-related transcriptional attenuator domain
MHPFIANA_00744 4.2e-219 K Cell envelope-related transcriptional attenuator domain
MHPFIANA_00745 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
MHPFIANA_00746 0.0 S Glycosyl transferase, family 2
MHPFIANA_00747 9.7e-222
MHPFIANA_00748 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
MHPFIANA_00749 2.5e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
MHPFIANA_00750 8.5e-139 ctsW S Phosphoribosyl transferase domain
MHPFIANA_00751 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
MHPFIANA_00752 2e-129 T Response regulator receiver domain protein
MHPFIANA_00753 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHPFIANA_00754 3e-102 carD K CarD-like/TRCF domain
MHPFIANA_00755 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MHPFIANA_00756 3.9e-140 znuB U ABC 3 transport family
MHPFIANA_00757 2e-160 znuC P ATPases associated with a variety of cellular activities
MHPFIANA_00758 2.2e-172 P Zinc-uptake complex component A periplasmic
MHPFIANA_00759 7.1e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHPFIANA_00760 8.3e-255 rpsA J Ribosomal protein S1
MHPFIANA_00761 2e-115 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHPFIANA_00762 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHPFIANA_00763 5.4e-14 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHPFIANA_00764 3.3e-158 terC P Integral membrane protein, TerC family
MHPFIANA_00765 2.5e-305 pyk 2.7.1.40 G Pyruvate kinase
MHPFIANA_00767 1.3e-18 relB L RelB antitoxin
MHPFIANA_00769 7.2e-196 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MHPFIANA_00770 3.2e-115 3.6.3.21 E ATPases associated with a variety of cellular activities
MHPFIANA_00771 1.4e-121 tcyA ET Bacterial periplasmic substrate-binding proteins
MHPFIANA_00772 8.2e-101 E Binding-protein-dependent transport system inner membrane component
MHPFIANA_00773 1.3e-37 pcrA1 3.6.4.12 F DNA helicase
MHPFIANA_00774 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
MHPFIANA_00775 2.3e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
MHPFIANA_00776 4.6e-49 2.1.1.72, 3.1.21.3 L Type I restriction modification DNA specificity domain
MHPFIANA_00777 3.1e-38 3.1.21.3 L Type I restriction modification DNA specificity domain
MHPFIANA_00778 1.4e-106 L Belongs to the 'phage' integrase family
MHPFIANA_00779 3e-164 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
MHPFIANA_00780 9.4e-101 pdtaR T Response regulator receiver domain protein
MHPFIANA_00781 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHPFIANA_00782 3.8e-165 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
MHPFIANA_00783 7.1e-121 3.6.1.13 L NUDIX domain
MHPFIANA_00784 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MHPFIANA_00785 3.1e-212 ykiI
MHPFIANA_00787 1.6e-129 L Phage integrase family
MHPFIANA_00788 7.6e-52
MHPFIANA_00789 1e-60 S HIRAN domain
MHPFIANA_00790 1.7e-13
MHPFIANA_00792 2.4e-21
MHPFIANA_00797 1.2e-63 ssb1 L single-stranded DNA-binding protein
MHPFIANA_00798 2.7e-48
MHPFIANA_00799 3.8e-09 S Helix-turn-helix domain
MHPFIANA_00800 9.5e-176 K ParB-like nuclease domain
MHPFIANA_00802 1.5e-49 V HNH endonuclease
MHPFIANA_00803 2.9e-78 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
MHPFIANA_00808 5e-12
MHPFIANA_00809 7.6e-50
MHPFIANA_00812 6.6e-17 msi109 K Helix-turn-helix domain
MHPFIANA_00813 1.7e-135 J tRNA 5'-leader removal
MHPFIANA_00814 1.6e-26 J tRNA 5'-leader removal
MHPFIANA_00815 1.4e-27 K Transcriptional regulator
MHPFIANA_00819 3.7e-62
MHPFIANA_00820 1.6e-262 S Terminase
MHPFIANA_00821 1.9e-105 S Phage portal protein, SPP1 Gp6-like
MHPFIANA_00822 1.7e-69
MHPFIANA_00824 6e-46 S Phage capsid family
MHPFIANA_00825 1.6e-11
MHPFIANA_00826 5.6e-44
MHPFIANA_00827 9.2e-49
MHPFIANA_00828 1.1e-66
MHPFIANA_00829 1.7e-85
MHPFIANA_00830 3.8e-82
MHPFIANA_00831 2e-08
MHPFIANA_00832 0.0 S Phage-related minor tail protein
MHPFIANA_00833 1.1e-150
MHPFIANA_00834 3.5e-219 S Psort location Cytoplasmic, score
MHPFIANA_00836 1.2e-122
MHPFIANA_00837 1.4e-29
MHPFIANA_00840 3.4e-28
MHPFIANA_00841 1.6e-144 L DNA integration
MHPFIANA_00842 1.4e-10 MU outer membrane autotransporter barrel domain protein
MHPFIANA_00843 3.8e-181
MHPFIANA_00844 3.1e-97 L reverse transcriptase
MHPFIANA_00847 2.2e-19
MHPFIANA_00848 2.4e-197 M Glycosyl hydrolases family 25
MHPFIANA_00849 5.8e-28 S Putative phage holin Dp-1
MHPFIANA_00850 1.4e-256 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHPFIANA_00852 3.8e-70 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
MHPFIANA_00853 4.9e-75 yiaC K Acetyltransferase (GNAT) domain
MHPFIANA_00854 5.1e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MHPFIANA_00855 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
MHPFIANA_00856 5.6e-300 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MHPFIANA_00857 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHPFIANA_00858 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
MHPFIANA_00859 2.8e-244 pbuX F Permease family
MHPFIANA_00860 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHPFIANA_00861 0.0 pcrA 3.6.4.12 L DNA helicase
MHPFIANA_00862 1.7e-61 S Domain of unknown function (DUF4418)
MHPFIANA_00863 1.8e-215 V FtsX-like permease family
MHPFIANA_00864 1.9e-150 lolD V ABC transporter
MHPFIANA_00865 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHPFIANA_00866 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MHPFIANA_00867 5.6e-129 pgm3 G Phosphoglycerate mutase family
MHPFIANA_00868 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
MHPFIANA_00869 2.5e-36
MHPFIANA_00870 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHPFIANA_00871 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHPFIANA_00872 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHPFIANA_00873 9.3e-57 3.4.23.43 S Type IV leader peptidase family
MHPFIANA_00874 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHPFIANA_00875 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHPFIANA_00876 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MHPFIANA_00877 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
MHPFIANA_00878 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHPFIANA_00879 0.0 S L,D-transpeptidase catalytic domain
MHPFIANA_00880 9.6e-291 sufB O FeS assembly protein SufB
MHPFIANA_00881 1e-234 sufD O FeS assembly protein SufD
MHPFIANA_00882 1e-142 sufC O FeS assembly ATPase SufC
MHPFIANA_00883 9.4e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHPFIANA_00884 2.6e-97 iscU C SUF system FeS assembly protein, NifU family
MHPFIANA_00885 2.7e-108 yitW S Iron-sulfur cluster assembly protein
MHPFIANA_00886 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHPFIANA_00887 3.5e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
MHPFIANA_00889 2e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHPFIANA_00890 1.8e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
MHPFIANA_00891 6.5e-207 phoH T PhoH-like protein
MHPFIANA_00892 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHPFIANA_00893 4.1e-251 corC S CBS domain
MHPFIANA_00894 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHPFIANA_00895 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MHPFIANA_00896 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
MHPFIANA_00897 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
MHPFIANA_00898 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MHPFIANA_00899 1.9e-269 S Psort location Cytoplasmic, score 8.87
MHPFIANA_00901 4.6e-225 G Transmembrane secretion effector
MHPFIANA_00902 1e-119 K Bacterial regulatory proteins, tetR family
MHPFIANA_00903 1.1e-39 nrdH O Glutaredoxin
MHPFIANA_00904 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
MHPFIANA_00905 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPFIANA_00907 8.2e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPFIANA_00908 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MHPFIANA_00910 2.6e-30 EGP Major facilitator Superfamily
MHPFIANA_00911 1.3e-25 yhjX EGP Major facilitator Superfamily
MHPFIANA_00912 8.5e-195 S alpha beta
MHPFIANA_00913 6.5e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MHPFIANA_00914 4.1e-92 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPFIANA_00915 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPFIANA_00916 2.6e-73 K Acetyltransferase (GNAT) domain
MHPFIANA_00918 1.9e-227 ilvE 2.6.1.42 E Amino-transferase class IV
MHPFIANA_00919 1.1e-133 S UPF0126 domain
MHPFIANA_00920 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
MHPFIANA_00921 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHPFIANA_00922 1.5e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
MHPFIANA_00923 3.2e-144 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MHPFIANA_00924 6.9e-289 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
MHPFIANA_00925 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
MHPFIANA_00926 8.7e-235 F Psort location CytoplasmicMembrane, score 10.00
MHPFIANA_00927 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
MHPFIANA_00928 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MHPFIANA_00929 2e-74
MHPFIANA_00930 2.9e-248 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
MHPFIANA_00931 7.9e-157 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
MHPFIANA_00932 1.9e-197 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MHPFIANA_00933 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
MHPFIANA_00934 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHPFIANA_00935 1.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
MHPFIANA_00936 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
MHPFIANA_00937 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MHPFIANA_00938 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
MHPFIANA_00939 5.2e-278 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHPFIANA_00940 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
MHPFIANA_00941 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
MHPFIANA_00942 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHPFIANA_00943 2.7e-123 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHPFIANA_00944 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
MHPFIANA_00945 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MHPFIANA_00946 8.8e-109 J Acetyltransferase (GNAT) domain
MHPFIANA_00947 2.6e-67 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHPFIANA_00948 8.1e-218 yxjG_1 E Psort location Cytoplasmic, score 8.87
MHPFIANA_00949 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MHPFIANA_00950 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPFIANA_00951 1.4e-139 S SdpI/YhfL protein family
MHPFIANA_00952 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MHPFIANA_00953 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHPFIANA_00954 5e-125 XK27_06785 V ABC transporter
MHPFIANA_00957 4.3e-63
MHPFIANA_00958 1.6e-95 M Peptidase family M23
MHPFIANA_00959 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
MHPFIANA_00960 5.2e-268 G ABC transporter substrate-binding protein
MHPFIANA_00961 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
MHPFIANA_00962 1.1e-209 guaB 1.1.1.205 F IMP dehydrogenase family protein
MHPFIANA_00963 6.1e-108 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
MHPFIANA_00964 3.4e-71 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPFIANA_00965 2.6e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHPFIANA_00966 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHPFIANA_00967 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MHPFIANA_00968 6.2e-117
MHPFIANA_00970 1.3e-232 XK27_00240 K Fic/DOC family
MHPFIANA_00971 9.2e-71 pdxH S Pfam:Pyridox_oxidase
MHPFIANA_00972 2.7e-302 M domain protein
MHPFIANA_00973 5.2e-65 3.4.22.70 M Sortase family
MHPFIANA_00974 2.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MHPFIANA_00975 5.7e-172 corA P CorA-like Mg2+ transporter protein
MHPFIANA_00976 1.5e-142 ET Bacterial periplasmic substrate-binding proteins
MHPFIANA_00977 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPFIANA_00978 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
MHPFIANA_00979 0.0 comE S Competence protein
MHPFIANA_00980 6.5e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
MHPFIANA_00981 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
MHPFIANA_00982 6.4e-148 yeaZ 2.3.1.234 O Glycoprotease family
MHPFIANA_00983 7.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
MHPFIANA_00984 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHPFIANA_00986 4.6e-119 yoaP E YoaP-like
MHPFIANA_00987 4.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHPFIANA_00988 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
MHPFIANA_00989 4.4e-198 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MHPFIANA_00990 2.4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
MHPFIANA_00991 6e-221 yxjG_1 E Psort location Cytoplasmic, score 8.87
MHPFIANA_00992 3.6e-76 S Psort location CytoplasmicMembrane, score
MHPFIANA_00993 1e-182 cat P Cation efflux family
MHPFIANA_00996 3.5e-99
MHPFIANA_00997 2.9e-130
MHPFIANA_00998 5.7e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
MHPFIANA_00999 6.7e-278 pepC 3.4.22.40 E Peptidase C1-like family
MHPFIANA_01000 1e-173 S IMP dehydrogenase activity
MHPFIANA_01001 1.3e-298 ybiT S ABC transporter
MHPFIANA_01002 4.7e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
MHPFIANA_01003 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MHPFIANA_01005 2e-13
MHPFIANA_01006 6.4e-272 S Psort location Cytoplasmic, score 8.87
MHPFIANA_01007 4.7e-140 S Domain of unknown function (DUF4194)
MHPFIANA_01008 0.0 S Psort location Cytoplasmic, score 8.87
MHPFIANA_01009 1e-218 S Psort location Cytoplasmic, score 8.87
MHPFIANA_01010 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHPFIANA_01011 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHPFIANA_01012 6e-182 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
MHPFIANA_01013 1.1e-170 rapZ S Displays ATPase and GTPase activities
MHPFIANA_01014 1.3e-171 whiA K May be required for sporulation
MHPFIANA_01015 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
MHPFIANA_01016 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHPFIANA_01017 2.4e-32 secG U Preprotein translocase SecG subunit
MHPFIANA_01018 3.3e-163 S Sucrose-6F-phosphate phosphohydrolase
MHPFIANA_01019 8e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
MHPFIANA_01020 1.2e-08 pnuC H Nicotinamide mononucleotide transporter
MHPFIANA_01021 5.6e-112 pnuC H Nicotinamide mononucleotide transporter
MHPFIANA_01022 2.5e-49 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H ATPase kinase involved in NAD metabolism
MHPFIANA_01023 2.2e-41 nadR H ATPase kinase involved in NAD metabolism
MHPFIANA_01024 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHPFIANA_01025 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
MHPFIANA_01026 3.9e-196 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHPFIANA_01027 4.7e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHPFIANA_01028 3.3e-157 G Fructosamine kinase
MHPFIANA_01029 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHPFIANA_01030 1.6e-156 S PAC2 family
MHPFIANA_01038 5.4e-36
MHPFIANA_01039 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
MHPFIANA_01040 9.7e-112 K helix_turn_helix, mercury resistance
MHPFIANA_01041 4.6e-61
MHPFIANA_01042 1.5e-140 pgp 3.1.3.18 S HAD-hyrolase-like
MHPFIANA_01043 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
MHPFIANA_01044 0.0 helY L DEAD DEAH box helicase
MHPFIANA_01045 2.1e-54
MHPFIANA_01046 0.0 pafB K WYL domain
MHPFIANA_01047 3.7e-265 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
MHPFIANA_01049 1.1e-69
MHPFIANA_01050 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
MHPFIANA_01051 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHPFIANA_01052 2.2e-160 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MHPFIANA_01053 8.2e-34
MHPFIANA_01054 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MHPFIANA_01055 1.8e-246
MHPFIANA_01056 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MHPFIANA_01057 4.9e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MHPFIANA_01058 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHPFIANA_01059 1.8e-50 yajC U Preprotein translocase subunit
MHPFIANA_01060 5.6e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHPFIANA_01061 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHPFIANA_01062 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MHPFIANA_01063 5.2e-128 yebC K transcriptional regulatory protein
MHPFIANA_01064 3.5e-112 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
MHPFIANA_01065 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHPFIANA_01066 1.6e-141 S Bacterial protein of unknown function (DUF881)
MHPFIANA_01067 4.2e-45 sbp S Protein of unknown function (DUF1290)
MHPFIANA_01068 4.9e-171 S Bacterial protein of unknown function (DUF881)
MHPFIANA_01069 1e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHPFIANA_01070 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
MHPFIANA_01071 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
MHPFIANA_01072 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
MHPFIANA_01073 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHPFIANA_01074 9.3e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHPFIANA_01075 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHPFIANA_01076 2.1e-293 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MHPFIANA_01077 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MHPFIANA_01078 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHPFIANA_01079 3.2e-225 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MHPFIANA_01080 6.1e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
MHPFIANA_01081 5.8e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHPFIANA_01082 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MHPFIANA_01084 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHPFIANA_01085 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
MHPFIANA_01086 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHPFIANA_01087 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
MHPFIANA_01088 1.8e-121
MHPFIANA_01090 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHPFIANA_01091 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHPFIANA_01092 3.2e-101
MHPFIANA_01093 2.9e-243 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHPFIANA_01094 6.5e-251 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHPFIANA_01095 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
MHPFIANA_01096 1e-232 EGP Major facilitator Superfamily
MHPFIANA_01097 1e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
MHPFIANA_01098 7.4e-174 G Fic/DOC family
MHPFIANA_01099 3.8e-144
MHPFIANA_01100 6.9e-164 IQ Enoyl-(Acyl carrier protein) reductase
MHPFIANA_01101 5.3e-167 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MHPFIANA_01102 7.4e-77 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MHPFIANA_01103 1.9e-95 bcp 1.11.1.15 O Redoxin
MHPFIANA_01104 2.7e-24 S Psort location Cytoplasmic, score 8.87
MHPFIANA_01105 1.1e-95 S Pyridoxamine 5'-phosphate oxidase
MHPFIANA_01106 0.0 S Histidine phosphatase superfamily (branch 2)
MHPFIANA_01107 6e-44 L transposition
MHPFIANA_01108 1.1e-23 C Acetamidase/Formamidase family
MHPFIANA_01109 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
MHPFIANA_01110 2.3e-173 V ATPases associated with a variety of cellular activities
MHPFIANA_01111 4.4e-116 S ABC-2 family transporter protein
MHPFIANA_01112 2.4e-121 S Haloacid dehalogenase-like hydrolase
MHPFIANA_01113 3.7e-262 recN L May be involved in recombinational repair of damaged DNA
MHPFIANA_01114 2e-177 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHPFIANA_01115 2.1e-266 trkB P Cation transport protein
MHPFIANA_01116 3e-116 trkA P TrkA-N domain
MHPFIANA_01117 2.9e-134 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MHPFIANA_01118 1.1e-192 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MHPFIANA_01119 1.9e-141 L Tetratricopeptide repeat
MHPFIANA_01120 1.3e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHPFIANA_01121 0.0 S Protein of unknown function (DUF975)
MHPFIANA_01122 8.6e-137 S Putative ABC-transporter type IV
MHPFIANA_01123 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MHPFIANA_01124 1.3e-279 argH 4.3.2.1 E argininosuccinate lyase
MHPFIANA_01125 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHPFIANA_01126 2.3e-82 argR K Regulates arginine biosynthesis genes
MHPFIANA_01127 1e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHPFIANA_01128 6.4e-243 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
MHPFIANA_01129 1.8e-178 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MHPFIANA_01130 8.8e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHPFIANA_01131 2.2e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHPFIANA_01132 1.9e-98
MHPFIANA_01133 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
MHPFIANA_01134 2.4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHPFIANA_01135 3.3e-158 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHPFIANA_01136 1.5e-97 yvdD 3.2.2.10 S Possible lysine decarboxylase
MHPFIANA_01138 4.5e-18
MHPFIANA_01140 1.5e-17 L HNH endonuclease
MHPFIANA_01141 2.2e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
MHPFIANA_01142 4e-42 V DNA modification
MHPFIANA_01143 7.8e-282 glnA 6.3.1.2 E glutamine synthetase
MHPFIANA_01144 6e-143 S Domain of unknown function (DUF4191)
MHPFIANA_01145 8.4e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MHPFIANA_01146 3.6e-93 S Protein of unknown function (DUF3043)
MHPFIANA_01147 1e-251 argE E Peptidase dimerisation domain
MHPFIANA_01148 3.1e-145 cbiQ P Cobalt transport protein
MHPFIANA_01149 1.2e-264 ykoD P ATPases associated with a variety of cellular activities
MHPFIANA_01150 2.9e-84 ykoE S ABC-type cobalt transport system, permease component
MHPFIANA_01151 2.6e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MHPFIANA_01152 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHPFIANA_01153 0.0 S Tetratricopeptide repeat
MHPFIANA_01154 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHPFIANA_01155 1.6e-302 2.8.2.22 S Arylsulfotransferase Ig-like domain
MHPFIANA_01156 4.4e-141 bioM P ATPases associated with a variety of cellular activities
MHPFIANA_01157 8.8e-215 E Aminotransferase class I and II
MHPFIANA_01158 9.3e-141 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
MHPFIANA_01159 3e-195 S Glycosyltransferase, group 2 family protein
MHPFIANA_01160 3.4e-143 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MHPFIANA_01161 2.4e-47 yhbY J CRS1_YhbY
MHPFIANA_01162 0.0 ecfA GP ABC transporter, ATP-binding protein
MHPFIANA_01163 6.1e-109 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHPFIANA_01164 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
MHPFIANA_01165 1.4e-112 kcsA U Ion channel
MHPFIANA_01166 2.2e-187 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHPFIANA_01167 6.6e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHPFIANA_01168 1.2e-123 3.2.1.8 S alpha beta
MHPFIANA_01169 4.3e-25
MHPFIANA_01170 3.9e-269 L Uncharacterized conserved protein (DUF2075)
MHPFIANA_01171 2.5e-14 mazG S MazG-like family
MHPFIANA_01172 4.9e-50 S Putative inner membrane protein (DUF1819)
MHPFIANA_01173 8e-12 S Putative inner membrane protein (DUF1819)
MHPFIANA_01174 1.1e-130 K Helix-turn-helix domain protein
MHPFIANA_01176 4.8e-210
MHPFIANA_01177 7.8e-148 S phosphoesterase or phosphohydrolase
MHPFIANA_01178 7e-41 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHPFIANA_01179 1.4e-71 4.1.1.44 S Cupin domain
MHPFIANA_01180 2.3e-166 C Aldo/keto reductase family
MHPFIANA_01181 3.2e-127 E Psort location Cytoplasmic, score 8.87
MHPFIANA_01182 2.7e-132 yebE S DUF218 domain
MHPFIANA_01183 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHPFIANA_01184 2.6e-236 rnd 3.1.13.5 J 3'-5' exonuclease
MHPFIANA_01185 9.9e-80 S Protein of unknown function (DUF3000)
MHPFIANA_01186 7.4e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHPFIANA_01187 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MHPFIANA_01188 4.5e-31
MHPFIANA_01189 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MHPFIANA_01190 1.2e-211 S Peptidase dimerisation domain
MHPFIANA_01191 1.3e-93 metI P Binding-protein-dependent transport system inner membrane component
MHPFIANA_01192 2.5e-174 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHPFIANA_01193 3.7e-150 metQ P NLPA lipoprotein
MHPFIANA_01195 5.1e-113 S Sucrose-6F-phosphate phosphohydrolase
MHPFIANA_01196 0.0 S LPXTG-motif cell wall anchor domain protein
MHPFIANA_01197 4.1e-243 dinF V MatE
MHPFIANA_01198 1.2e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHPFIANA_01199 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHPFIANA_01200 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
MHPFIANA_01201 1e-47 S Domain of unknown function (DUF4193)
MHPFIANA_01202 4.1e-147 S Protein of unknown function (DUF3071)
MHPFIANA_01203 3e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
MHPFIANA_01204 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MHPFIANA_01205 0.0 lhr L DEAD DEAH box helicase
MHPFIANA_01206 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
MHPFIANA_01207 9.2e-79 S Protein of unknown function (DUF2975)
MHPFIANA_01208 7.3e-242 T PhoQ Sensor
MHPFIANA_01209 3.4e-222 G Major Facilitator Superfamily
MHPFIANA_01210 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
MHPFIANA_01211 9.7e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHPFIANA_01212 1.1e-118
MHPFIANA_01213 3.4e-197 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
MHPFIANA_01214 0.0 pknL 2.7.11.1 KLT PASTA
MHPFIANA_01215 4.3e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
MHPFIANA_01216 1.4e-96
MHPFIANA_01217 6.5e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHPFIANA_01218 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHPFIANA_01219 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHPFIANA_01220 3.5e-123 recX S Modulates RecA activity
MHPFIANA_01221 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHPFIANA_01222 4.3e-46 S Protein of unknown function (DUF3046)
MHPFIANA_01223 1.6e-80 K Helix-turn-helix XRE-family like proteins
MHPFIANA_01224 5.5e-98 cinA 3.5.1.42 S Belongs to the CinA family
MHPFIANA_01225 1.6e-123 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHPFIANA_01226 0.0 ftsK D FtsK SpoIIIE family protein
MHPFIANA_01227 1.9e-192 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHPFIANA_01228 1e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MHPFIANA_01229 4.2e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
MHPFIANA_01230 8e-177 ydeD EG EamA-like transporter family
MHPFIANA_01231 6.4e-127 ybhL S Belongs to the BI1 family
MHPFIANA_01232 1.4e-57 S Domain of unknown function (DUF5067)
MHPFIANA_01233 5.1e-243 T Histidine kinase
MHPFIANA_01234 1.8e-127 K helix_turn_helix, Lux Regulon
MHPFIANA_01235 0.0 S Protein of unknown function DUF262
MHPFIANA_01236 9e-116 K helix_turn_helix, Lux Regulon
MHPFIANA_01237 4.6e-244 T Histidine kinase
MHPFIANA_01238 2.9e-190 V ATPases associated with a variety of cellular activities
MHPFIANA_01239 7.7e-225 V ABC-2 family transporter protein
MHPFIANA_01240 8.9e-229 V ABC-2 family transporter protein
MHPFIANA_01241 3.7e-212 rhaR1 K helix_turn_helix, arabinose operon control protein
MHPFIANA_01242 6.3e-106 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
MHPFIANA_01243 7.8e-247 VP1224 V Psort location CytoplasmicMembrane, score 9.99
MHPFIANA_01244 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MHPFIANA_01245 0.0 ctpE P E1-E2 ATPase
MHPFIANA_01246 2e-74
MHPFIANA_01247 2.8e-243 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHPFIANA_01248 2.4e-133 S Protein of unknown function (DUF3159)
MHPFIANA_01249 2.4e-150 S Protein of unknown function (DUF3710)
MHPFIANA_01250 3e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
MHPFIANA_01251 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
MHPFIANA_01252 1.4e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
MHPFIANA_01253 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
MHPFIANA_01254 0.0 E ABC transporter, substrate-binding protein, family 5
MHPFIANA_01255 0.0 E ABC transporter, substrate-binding protein, family 5
MHPFIANA_01256 1.8e-170 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MHPFIANA_01257 5.2e-08
MHPFIANA_01258 2.8e-34
MHPFIANA_01259 3.4e-194 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
MHPFIANA_01260 4.8e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
MHPFIANA_01261 1.7e-102
MHPFIANA_01262 0.0 typA T Elongation factor G C-terminus
MHPFIANA_01263 1.7e-249 naiP U Sugar (and other) transporter
MHPFIANA_01264 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
MHPFIANA_01265 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MHPFIANA_01266 1.3e-176 xerD D recombinase XerD
MHPFIANA_01267 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHPFIANA_01268 2.1e-25 rpmI J Ribosomal protein L35
MHPFIANA_01269 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHPFIANA_01270 9.2e-109 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
MHPFIANA_01271 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHPFIANA_01272 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHPFIANA_01273 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MHPFIANA_01274 4.3e-188 galM 5.1.3.3 G Aldose 1-epimerase
MHPFIANA_01275 4.1e-37
MHPFIANA_01276 1.3e-97 sigH K Belongs to the sigma-70 factor family. ECF subfamily
MHPFIANA_01277 5.8e-275 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHPFIANA_01278 6.6e-187 V Acetyltransferase (GNAT) domain
MHPFIANA_01279 2.5e-289 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
MHPFIANA_01280 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
MHPFIANA_01281 2e-94 3.6.1.55 F NUDIX domain
MHPFIANA_01282 0.0 P Belongs to the ABC transporter superfamily
MHPFIANA_01283 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
MHPFIANA_01284 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
MHPFIANA_01285 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
MHPFIANA_01286 1.7e-218 GK ROK family
MHPFIANA_01287 1.1e-164 2.7.1.4 G pfkB family carbohydrate kinase
MHPFIANA_01288 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
MHPFIANA_01289 1.6e-27
MHPFIANA_01290 8.4e-248 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
MHPFIANA_01291 1.7e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
MHPFIANA_01292 2.3e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
MHPFIANA_01293 6.3e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHPFIANA_01294 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
MHPFIANA_01295 2.1e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHPFIANA_01296 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHPFIANA_01297 6.4e-263 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHPFIANA_01298 1.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHPFIANA_01299 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
MHPFIANA_01300 1.8e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MHPFIANA_01301 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHPFIANA_01302 7e-92 mraZ K Belongs to the MraZ family
MHPFIANA_01303 0.0 L DNA helicase
MHPFIANA_01304 4.3e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
MHPFIANA_01305 8.5e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHPFIANA_01306 2.3e-53 M Lysin motif
MHPFIANA_01307 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHPFIANA_01308 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPFIANA_01309 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
MHPFIANA_01310 1.9e-270 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHPFIANA_01311 2.9e-113 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
MHPFIANA_01312 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
MHPFIANA_01313 4.7e-191
MHPFIANA_01314 9.5e-184 V N-Acetylmuramoyl-L-alanine amidase
MHPFIANA_01315 1.7e-80
MHPFIANA_01316 3.2e-118 ytrE V ATPases associated with a variety of cellular activities
MHPFIANA_01317 9.5e-220 EGP Major facilitator Superfamily
MHPFIANA_01318 3.6e-139 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
MHPFIANA_01319 9.9e-216 S Domain of unknown function (DUF5067)
MHPFIANA_01320 3.1e-264 glnA2 6.3.1.2 E glutamine synthetase
MHPFIANA_01321 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
MHPFIANA_01322 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHPFIANA_01323 1.5e-122
MHPFIANA_01324 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
MHPFIANA_01325 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHPFIANA_01326 4.5e-258 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHPFIANA_01327 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
MHPFIANA_01328 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MHPFIANA_01329 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHPFIANA_01330 4.5e-31 3.1.21.3 V DivIVA protein
MHPFIANA_01331 6.9e-41 yggT S YGGT family
MHPFIANA_01332 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHPFIANA_01333 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHPFIANA_01334 1.9e-244 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHPFIANA_01335 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
MHPFIANA_01336 1e-105 S Pilus assembly protein, PilO
MHPFIANA_01337 8.1e-166 pilN NU PFAM Fimbrial assembly family protein
MHPFIANA_01338 8.7e-190 pilM NU Type IV pilus assembly protein PilM;
MHPFIANA_01339 2.4e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MHPFIANA_01340 0.0
MHPFIANA_01341 4.7e-230 pilC U Type II secretion system (T2SS), protein F
MHPFIANA_01342 2.4e-46 pilA NU Prokaryotic N-terminal methylation motif
MHPFIANA_01343 2.1e-104 S Prokaryotic N-terminal methylation motif
MHPFIANA_01344 4.9e-137 ppdC NU Prokaryotic N-terminal methylation motif
MHPFIANA_01345 0.0 pulE NU Type II/IV secretion system protein
MHPFIANA_01346 0.0 pilT NU Type II/IV secretion system protein
MHPFIANA_01347 0.0
MHPFIANA_01348 9.9e-155 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHPFIANA_01349 2e-132 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHPFIANA_01350 2.9e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHPFIANA_01351 3e-60 S Thiamine-binding protein
MHPFIANA_01352 3.7e-193 K helix_turn _helix lactose operon repressor
MHPFIANA_01353 2.8e-241 lacY P LacY proton/sugar symporter
MHPFIANA_01354 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MHPFIANA_01355 3.2e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_01356 5.3e-206 P NMT1/THI5 like
MHPFIANA_01357 2.1e-217 iunH1 3.2.2.1 F nucleoside hydrolase
MHPFIANA_01358 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHPFIANA_01359 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
MHPFIANA_01360 0.0 I acetylesterase activity
MHPFIANA_01361 5.6e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MHPFIANA_01362 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MHPFIANA_01363 1.1e-236 2.7.11.1 NU Tfp pilus assembly protein FimV
MHPFIANA_01365 6.5e-75 S Protein of unknown function (DUF3052)
MHPFIANA_01366 1.3e-154 lon T Belongs to the peptidase S16 family
MHPFIANA_01367 3.3e-294 S Zincin-like metallopeptidase
MHPFIANA_01368 1.8e-281 uvrD2 3.6.4.12 L DNA helicase
MHPFIANA_01369 9.4e-270 mphA S Aminoglycoside phosphotransferase
MHPFIANA_01370 3.6e-32 S Protein of unknown function (DUF3107)
MHPFIANA_01371 5e-173 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
MHPFIANA_01372 2.1e-117 S Vitamin K epoxide reductase
MHPFIANA_01373 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
MHPFIANA_01374 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MHPFIANA_01375 2.1e-21 S lipid catabolic process
MHPFIANA_01376 3e-301 E ABC transporter, substrate-binding protein, family 5
MHPFIANA_01377 4.9e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
MHPFIANA_01378 6.5e-156 S Patatin-like phospholipase
MHPFIANA_01379 2.5e-186 K LysR substrate binding domain protein
MHPFIANA_01380 1.6e-240 patB 4.4.1.8 E Aminotransferase, class I II
MHPFIANA_01381 1.1e-121 S Phospholipase/Carboxylesterase
MHPFIANA_01382 7.8e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHPFIANA_01383 3.3e-197 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
MHPFIANA_01384 4.5e-131 cas4 3.1.12.1 L Domain of unknown function DUF83
MHPFIANA_01385 4.5e-152 csd2 L CRISPR-associated protein Cas7
MHPFIANA_01386 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
MHPFIANA_01387 1.5e-137 cas5d S CRISPR-associated protein (Cas_Cas5)
MHPFIANA_01388 0.0 cas3 L DEAD-like helicases superfamily
MHPFIANA_01389 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHPFIANA_01390 1.1e-256 lacS G Psort location CytoplasmicMembrane, score 10.00
MHPFIANA_01391 9e-184 lacR K Transcriptional regulator, LacI family
MHPFIANA_01392 0.0 V ABC transporter transmembrane region
MHPFIANA_01393 0.0 V ABC transporter, ATP-binding protein
MHPFIANA_01394 1.3e-96 K MarR family
MHPFIANA_01395 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
MHPFIANA_01396 1.5e-106 K Bacterial regulatory proteins, tetR family
MHPFIANA_01397 4.8e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MHPFIANA_01398 9.3e-181 G Transporter major facilitator family protein
MHPFIANA_01399 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
MHPFIANA_01400 2.2e-214 EGP Major facilitator Superfamily
MHPFIANA_01401 8.9e-118 K Periplasmic binding protein domain
MHPFIANA_01402 4.5e-14 K helix_turn_helix, mercury resistance
MHPFIANA_01403 8e-221 lmrB U Major Facilitator Superfamily
MHPFIANA_01404 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
MHPFIANA_01405 2.3e-113 K Bacterial regulatory proteins, tetR family
MHPFIANA_01406 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
MHPFIANA_01407 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
MHPFIANA_01408 1.9e-233 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
MHPFIANA_01409 7.5e-239 G Transporter major facilitator family protein
MHPFIANA_01410 2.3e-105 K Bacterial regulatory proteins, tetR family
MHPFIANA_01411 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
MHPFIANA_01412 4.2e-115 K Bacterial regulatory proteins, tetR family
MHPFIANA_01413 8.9e-253 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
MHPFIANA_01414 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
MHPFIANA_01415 5.2e-156 hgdC I BadF/BadG/BcrA/BcrD ATPase family
MHPFIANA_01416 1.6e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHPFIANA_01417 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
MHPFIANA_01418 8.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHPFIANA_01419 7e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHPFIANA_01421 1.2e-197 S Endonuclease/Exonuclease/phosphatase family
MHPFIANA_01423 4.6e-43 V ATPases associated with a variety of cellular activities
MHPFIANA_01424 1.1e-22
MHPFIANA_01425 2e-86 tmp1 S Domain of unknown function (DUF4391)
MHPFIANA_01426 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
MHPFIANA_01427 4.7e-232 aspB E Aminotransferase class-V
MHPFIANA_01428 8.6e-74 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
MHPFIANA_01429 2e-191 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
MHPFIANA_01430 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
MHPFIANA_01431 8.4e-201 V Domain of unknown function (DUF3427)
MHPFIANA_01432 1.5e-76
MHPFIANA_01433 7.5e-71 S Bacterial PH domain
MHPFIANA_01434 1.5e-247 S zinc finger
MHPFIANA_01436 2.7e-291 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
MHPFIANA_01437 5.2e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHPFIANA_01438 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHPFIANA_01439 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
MHPFIANA_01440 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHPFIANA_01441 9.5e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHPFIANA_01442 0.0 pacS 3.6.3.54 P E1-E2 ATPase
MHPFIANA_01443 1.1e-38 csoR S Metal-sensitive transcriptional repressor
MHPFIANA_01444 1.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHPFIANA_01445 1.7e-246 G Major Facilitator Superfamily
MHPFIANA_01446 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
MHPFIANA_01447 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
MHPFIANA_01448 1.4e-262 KLT Protein tyrosine kinase
MHPFIANA_01449 0.0 S Fibronectin type 3 domain
MHPFIANA_01450 1.2e-231 S ATPase family associated with various cellular activities (AAA)
MHPFIANA_01451 2.4e-220 S Protein of unknown function DUF58
MHPFIANA_01452 0.0 E Transglutaminase-like superfamily
MHPFIANA_01453 4.4e-163 3.1.3.16 T Sigma factor PP2C-like phosphatases
MHPFIANA_01454 1.1e-102 B Belongs to the OprB family
MHPFIANA_01455 1.1e-101 T Forkhead associated domain
MHPFIANA_01456 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPFIANA_01457 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPFIANA_01458 1.5e-99
MHPFIANA_01459 9.3e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
MHPFIANA_01460 3.3e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHPFIANA_01461 4.7e-252 S UPF0210 protein
MHPFIANA_01462 7.1e-43 gcvR T Belongs to the UPF0237 family
MHPFIANA_01463 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
MHPFIANA_01464 1.6e-178 K helix_turn _helix lactose operon repressor
MHPFIANA_01465 3.5e-115 S Protein of unknown function, DUF624
MHPFIANA_01466 3.4e-169 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01467 1.6e-177 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01468 2.2e-309 G Bacterial extracellular solute-binding protein
MHPFIANA_01469 9e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
MHPFIANA_01470 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
MHPFIANA_01471 3.4e-141 glpR K DeoR C terminal sensor domain
MHPFIANA_01472 8.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
MHPFIANA_01473 3.9e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
MHPFIANA_01474 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
MHPFIANA_01475 2.3e-133 glxR K helix_turn_helix, cAMP Regulatory protein
MHPFIANA_01476 3.5e-216 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
MHPFIANA_01477 1.6e-84 J TM2 domain
MHPFIANA_01478 2.2e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MHPFIANA_01479 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
MHPFIANA_01480 1.5e-236 S Uncharacterized conserved protein (DUF2183)
MHPFIANA_01481 1e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
MHPFIANA_01482 1.8e-206 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MHPFIANA_01483 3.8e-159 mhpC I Alpha/beta hydrolase family
MHPFIANA_01484 1.7e-113 F Domain of unknown function (DUF4916)
MHPFIANA_01485 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
MHPFIANA_01486 5.6e-170 S G5
MHPFIANA_01487 2.1e-88
MHPFIANA_01488 0.0 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MHPFIANA_01489 2.1e-224 C Polysaccharide pyruvyl transferase
MHPFIANA_01490 3.9e-209 GT2 M Glycosyltransferase like family 2
MHPFIANA_01491 7.1e-192 1.13.11.79 C Psort location Cytoplasmic, score 8.87
MHPFIANA_01492 4.7e-207 wbbI M transferase activity, transferring glycosyl groups
MHPFIANA_01493 6.9e-287 S Psort location CytoplasmicMembrane, score 9.99
MHPFIANA_01494 6e-255 S Psort location CytoplasmicMembrane, score 9.99
MHPFIANA_01495 1.1e-189 2.4.1.166 GT2 M Glycosyltransferase like family 2
MHPFIANA_01496 1.8e-158 cps1D M Domain of unknown function (DUF4422)
MHPFIANA_01497 0.0 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
MHPFIANA_01498 2.9e-72
MHPFIANA_01499 1.6e-28 K Cro/C1-type HTH DNA-binding domain
MHPFIANA_01500 6.5e-74
MHPFIANA_01501 3.7e-96 3.1.3.48 T Low molecular weight phosphatase family
MHPFIANA_01502 5.5e-246 wcoI DM Psort location CytoplasmicMembrane, score
MHPFIANA_01503 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MHPFIANA_01504 6.5e-148 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_01505 1.7e-162 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_01506 3e-270 G Bacterial extracellular solute-binding protein
MHPFIANA_01507 1.4e-184 K Psort location Cytoplasmic, score
MHPFIANA_01508 7e-97 K Psort location Cytoplasmic, score
MHPFIANA_01509 1.6e-47 L Integrase core domain
MHPFIANA_01510 2.8e-21 L Psort location Cytoplasmic, score 8.87
MHPFIANA_01511 8e-15 2.7.7.7 L Transposase, Mutator family
MHPFIANA_01514 8.5e-71 S AAA domain, putative AbiEii toxin, Type IV TA system
MHPFIANA_01515 2.1e-41 L Transposase, Mutator family
MHPFIANA_01516 2e-25 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MHPFIANA_01517 1.1e-84 pac 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHPFIANA_01518 4.2e-22 S protein conserved in bacteria
MHPFIANA_01519 2e-56 yccF S Inner membrane component domain
MHPFIANA_01520 1e-260 S Psort location CytoplasmicMembrane, score 9.99
MHPFIANA_01521 3.1e-77
MHPFIANA_01522 2.6e-39 S Psort location Cytoplasmic, score
MHPFIANA_01523 1e-71 S Psort location Cytoplasmic, score
MHPFIANA_01524 8.1e-29 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHPFIANA_01526 3.2e-45
MHPFIANA_01528 1.4e-17
MHPFIANA_01529 4.3e-107 cps2J S Polysaccharide biosynthesis protein
MHPFIANA_01530 2.6e-37 tagF 2.7.8.12 M Glycosyl transferase, family 2
MHPFIANA_01531 1.4e-49 S slime layer polysaccharide biosynthetic process
MHPFIANA_01532 2.5e-86 lpg2 2.4.1.337 GT4 M Glycosyl transferases group 1
MHPFIANA_01533 7.7e-59 I transferase activity, transferring acyl groups other than amino-acyl groups
MHPFIANA_01534 4.5e-37 rfaJ 2.4.1.44, 2.4.1.58 GT8 M Glycosyl transferase family 8
MHPFIANA_01536 1.8e-203 M Glycosyl transferase 4-like domain
MHPFIANA_01537 1e-215 M Domain of unknown function (DUF1972)
MHPFIANA_01538 6.6e-204 GT4 M Psort location Cytoplasmic, score 8.87
MHPFIANA_01539 2.2e-243 MA20_17390 GT4 M Glycosyl transferases group 1
MHPFIANA_01540 2e-250 cps2J S Polysaccharide biosynthesis protein
MHPFIANA_01541 9.5e-197 S Glycosyltransferase like family 2
MHPFIANA_01542 1e-109 H Hexapeptide repeat of succinyl-transferase
MHPFIANA_01543 6.1e-210 S Polysaccharide pyruvyl transferase
MHPFIANA_01544 2.2e-193 1.13.11.79 C Psort location Cytoplasmic, score 8.87
MHPFIANA_01546 1.9e-176 wzy S EpsG family
MHPFIANA_01547 4e-17 pslL G PFAM Acyltransferase
MHPFIANA_01548 7.7e-08 gumF G Fucose 4-O-acetylase and related acetyltransferases
MHPFIANA_01549 6.3e-168 S enterobacterial common antigen metabolic process
MHPFIANA_01550 1.2e-09
MHPFIANA_01551 9.4e-15
MHPFIANA_01552 2.1e-48
MHPFIANA_01553 1.7e-55
MHPFIANA_01554 1.1e-37
MHPFIANA_01555 2.1e-108 K helix_turn _helix lactose operon repressor
MHPFIANA_01556 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
MHPFIANA_01557 8.5e-127 msmF G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01558 4.2e-126 rafG G ABC transporter permease
MHPFIANA_01559 2.6e-186 amyE G Bacterial extracellular solute-binding protein
MHPFIANA_01560 1.9e-202
MHPFIANA_01561 0.0 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
MHPFIANA_01562 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
MHPFIANA_01563 3e-187 S Endonuclease/Exonuclease/phosphatase family
MHPFIANA_01564 1.3e-46
MHPFIANA_01565 1.2e-283 EGP Major facilitator Superfamily
MHPFIANA_01566 3.2e-242 T Diguanylate cyclase (GGDEF) domain protein
MHPFIANA_01567 3.5e-116 L Protein of unknown function (DUF1524)
MHPFIANA_01568 4.6e-165 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
MHPFIANA_01569 2.1e-241 mntH P H( )-stimulated, divalent metal cation uptake system
MHPFIANA_01570 8.9e-198 K helix_turn _helix lactose operon repressor
MHPFIANA_01571 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MHPFIANA_01572 3.8e-166 G ABC transporter permease
MHPFIANA_01573 6.9e-154 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01574 9.1e-240 G Bacterial extracellular solute-binding protein
MHPFIANA_01575 6.1e-129 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MHPFIANA_01576 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MHPFIANA_01577 0.0 cydD V ABC transporter transmembrane region
MHPFIANA_01578 0.0 fadD 6.2.1.3 I AMP-binding enzyme
MHPFIANA_01579 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MHPFIANA_01580 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
MHPFIANA_01581 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
MHPFIANA_01582 9.6e-211 K helix_turn _helix lactose operon repressor
MHPFIANA_01583 2.4e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
MHPFIANA_01584 1.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHPFIANA_01585 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
MHPFIANA_01586 9.1e-300 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHPFIANA_01587 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MHPFIANA_01588 4.8e-271 mmuP E amino acid
MHPFIANA_01589 8e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
MHPFIANA_01591 4.7e-122 cyaA 4.6.1.1 S CYTH
MHPFIANA_01592 1.2e-169 trxA2 O Tetratricopeptide repeat
MHPFIANA_01593 1.7e-179
MHPFIANA_01594 4.8e-195
MHPFIANA_01595 6.8e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
MHPFIANA_01596 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MHPFIANA_01597 2.1e-45 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MHPFIANA_01598 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHPFIANA_01599 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHPFIANA_01600 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHPFIANA_01601 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHPFIANA_01602 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHPFIANA_01603 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHPFIANA_01604 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
MHPFIANA_01605 4.5e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MHPFIANA_01607 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MHPFIANA_01608 3.3e-192 yfdV S Membrane transport protein
MHPFIANA_01609 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
MHPFIANA_01610 7.1e-175 M LPXTG-motif cell wall anchor domain protein
MHPFIANA_01611 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
MHPFIANA_01612 9.7e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MHPFIANA_01613 9.4e-98 mntP P Probably functions as a manganese efflux pump
MHPFIANA_01614 4.9e-134
MHPFIANA_01615 4.9e-134 KT Transcriptional regulatory protein, C terminal
MHPFIANA_01616 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHPFIANA_01617 1.6e-288 E Bacterial extracellular solute-binding proteins, family 5 Middle
MHPFIANA_01618 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHPFIANA_01619 0.0 S domain protein
MHPFIANA_01620 1.8e-69 tyrA 5.4.99.5 E Chorismate mutase type II
MHPFIANA_01621 1.3e-79 K helix_turn_helix ASNC type
MHPFIANA_01622 2.7e-246 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHPFIANA_01623 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
MHPFIANA_01624 2.1e-51 S Protein of unknown function (DUF2469)
MHPFIANA_01625 5.9e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
MHPFIANA_01626 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHPFIANA_01627 2.5e-286 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHPFIANA_01628 5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHPFIANA_01630 6.2e-134 K Psort location Cytoplasmic, score
MHPFIANA_01631 3.1e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
MHPFIANA_01632 2.7e-104 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHPFIANA_01633 1.2e-167 rmuC S RmuC family
MHPFIANA_01634 1.7e-133 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
MHPFIANA_01635 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHPFIANA_01636 3.3e-163 fahA Q Fumarylacetoacetate (FAA) hydrolase family
MHPFIANA_01637 6.5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MHPFIANA_01638 8e-79
MHPFIANA_01639 1.4e-209 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPFIANA_01640 2e-43 M Protein of unknown function (DUF3152)
MHPFIANA_01641 2.4e-08 M Protein of unknown function (DUF3152)
MHPFIANA_01642 1.4e-125 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
MHPFIANA_01643 7.5e-31 S zinc-ribbon domain
MHPFIANA_01646 3.3e-167 T Pfam Adenylate and Guanylate cyclase catalytic domain
MHPFIANA_01647 0.0 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MHPFIANA_01648 1.7e-70 rplI J Binds to the 23S rRNA
MHPFIANA_01649 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHPFIANA_01650 9.7e-70 ssb1 L Single-stranded DNA-binding protein
MHPFIANA_01651 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MHPFIANA_01652 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHPFIANA_01653 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHPFIANA_01654 1.1e-259 EGP Major Facilitator Superfamily
MHPFIANA_01655 3.3e-167 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MHPFIANA_01656 1.1e-197 K helix_turn _helix lactose operon repressor
MHPFIANA_01657 1e-60
MHPFIANA_01658 1.1e-17 relB L RelB antitoxin
MHPFIANA_01659 6.4e-24 S Addiction module toxin, RelE StbE family
MHPFIANA_01660 1.6e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MHPFIANA_01661 2.2e-254 S Domain of unknown function (DUF4143)
MHPFIANA_01662 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
MHPFIANA_01663 5e-234 glf 5.4.99.9 M UDP-galactopyranose mutase
MHPFIANA_01664 0.0 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
MHPFIANA_01665 3.8e-101 3.2.1.97 GH101 M Cell wall-binding repeat protein
MHPFIANA_01666 7.4e-207 S Predicted membrane protein (DUF2142)
MHPFIANA_01667 3.9e-259 3.2.1.97 GH101 S Psort location Extracellular, score
MHPFIANA_01668 1.1e-239 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
MHPFIANA_01669 4.2e-147 rgpC U Transport permease protein
MHPFIANA_01670 3.4e-181 GM GDP-mannose 4,6 dehydratase
MHPFIANA_01671 7.9e-137 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MHPFIANA_01672 3.7e-210 M LicD family
MHPFIANA_01673 0.0 2.4.1.288 GT2 S Glycosyltransferase like family 2
MHPFIANA_01674 2.5e-200 cps3I G Psort location CytoplasmicMembrane, score 9.99
MHPFIANA_01675 4.5e-196 3.1.1.5, 3.2.1.97 GH101 E GDSL-like Lipase/Acylhydrolase family
MHPFIANA_01676 1.1e-300
MHPFIANA_01677 7.2e-175 ykoT 2.4.1.83 GT2 M Glycosyl transferase family 2
MHPFIANA_01678 2.8e-250 lytC 3.2.1.17, 3.2.1.96, 3.2.1.97 GH101 M Glycosyl hydrolases family 25
MHPFIANA_01679 2.2e-257 S AAA domain
MHPFIANA_01680 4.3e-69
MHPFIANA_01681 2.4e-10
MHPFIANA_01682 4.4e-300 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
MHPFIANA_01683 1.1e-57
MHPFIANA_01685 2.3e-91 EGP Major facilitator Superfamily
MHPFIANA_01686 5.8e-59 EGP Major facilitator Superfamily
MHPFIANA_01688 0.0 S Psort location CytoplasmicMembrane, score 9.99
MHPFIANA_01689 3.6e-241 V ABC transporter permease
MHPFIANA_01690 4.2e-156 V ABC transporter
MHPFIANA_01691 5.1e-150 T HD domain
MHPFIANA_01692 1e-167 S Glutamine amidotransferase domain
MHPFIANA_01693 0.0 kup P Transport of potassium into the cell
MHPFIANA_01694 2.2e-184 tatD L TatD related DNase
MHPFIANA_01695 0.0 G Alpha-L-arabinofuranosidase C-terminus
MHPFIANA_01696 1.1e-232 G Alpha galactosidase A
MHPFIANA_01697 4.1e-223 K helix_turn _helix lactose operon repressor
MHPFIANA_01698 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
MHPFIANA_01699 3e-125
MHPFIANA_01700 0.0 yknV V ABC transporter
MHPFIANA_01701 0.0 mdlA2 V ABC transporter
MHPFIANA_01702 9.7e-216 lipA I Hydrolase, alpha beta domain protein
MHPFIANA_01703 5e-27 S Psort location Cytoplasmic, score 8.87
MHPFIANA_01704 3.8e-156 I alpha/beta hydrolase fold
MHPFIANA_01705 5.5e-233 M Protein of unknown function (DUF2961)
MHPFIANA_01706 3.2e-153 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_01707 8.5e-190 K helix_turn _helix lactose operon repressor
MHPFIANA_01708 2.6e-188 M probably involved in cell wall
MHPFIANA_01709 1.8e-237 M probably involved in cell wall
MHPFIANA_01710 2.1e-249 3.2.1.14 GH18 S Carbohydrate binding domain
MHPFIANA_01711 0.0 T Diguanylate cyclase, GGDEF domain
MHPFIANA_01712 1.5e-186 lacR K Transcriptional regulator, LacI family
MHPFIANA_01713 5.7e-231 nagA 3.5.1.25 G Amidohydrolase family
MHPFIANA_01714 1.2e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHPFIANA_01715 0.0 G Glycosyl hydrolase family 20, domain 2
MHPFIANA_01716 3e-173 2.7.1.2 GK ROK family
MHPFIANA_01717 4.4e-164 G ABC transporter permease
MHPFIANA_01718 7.5e-147 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01719 4.2e-242 G Bacterial extracellular solute-binding protein
MHPFIANA_01720 1.4e-209 GK ROK family
MHPFIANA_01721 1.6e-259 lacS G Psort location CytoplasmicMembrane, score 10.00
MHPFIANA_01722 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MHPFIANA_01723 6.6e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
MHPFIANA_01724 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MHPFIANA_01725 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHPFIANA_01726 6.6e-107
MHPFIANA_01727 8.8e-190 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHPFIANA_01728 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
MHPFIANA_01729 5.8e-126 dedA S SNARE associated Golgi protein
MHPFIANA_01731 3.3e-129 S HAD hydrolase, family IA, variant 3
MHPFIANA_01732 8.6e-47
MHPFIANA_01733 4.5e-115 hspR K transcriptional regulator, MerR family
MHPFIANA_01734 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
MHPFIANA_01735 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHPFIANA_01736 0.0 dnaK O Heat shock 70 kDa protein
MHPFIANA_01737 1.3e-145 S Mitochondrial biogenesis AIM24
MHPFIANA_01738 8.1e-54 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
MHPFIANA_01739 7e-127 S membrane transporter protein
MHPFIANA_01740 8.3e-193 K Psort location Cytoplasmic, score
MHPFIANA_01741 7.9e-129 traX S TraX protein
MHPFIANA_01742 7e-144 S HAD-hyrolase-like
MHPFIANA_01743 5.4e-292 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MHPFIANA_01744 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
MHPFIANA_01745 1.7e-13 S Transposon-encoded protein TnpV
MHPFIANA_01746 2.2e-108 pepE 3.4.13.21 E Peptidase family S51
MHPFIANA_01747 3.4e-106 S Protein of unknown function, DUF624
MHPFIANA_01748 7.6e-152 rafG G ABC transporter permease
MHPFIANA_01749 1.8e-153 msmF G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01750 1.7e-182 K Psort location Cytoplasmic, score
MHPFIANA_01751 1.8e-187 K Periplasmic binding protein-like domain
MHPFIANA_01752 3.2e-264 amyE G Bacterial extracellular solute-binding protein
MHPFIANA_01753 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
MHPFIANA_01754 3.9e-259 amyE G Bacterial extracellular solute-binding protein
MHPFIANA_01755 2.9e-136 G Phosphoglycerate mutase family
MHPFIANA_01756 1.9e-62 S Protein of unknown function (DUF4235)
MHPFIANA_01757 3.9e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
MHPFIANA_01758 1.7e-44
MHPFIANA_01759 4.4e-15
MHPFIANA_01760 5.7e-85 K Cro/C1-type HTH DNA-binding domain
MHPFIANA_01761 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
MHPFIANA_01762 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MHPFIANA_01763 1.7e-125 S Short repeat of unknown function (DUF308)
MHPFIANA_01764 2.7e-49 S Antitoxin component of a toxin-antitoxin (TA) module
MHPFIANA_01765 7.5e-55 DJ Addiction module toxin, RelE StbE family
MHPFIANA_01766 4.5e-13 S Psort location Extracellular, score 8.82
MHPFIANA_01767 3.3e-231 EGP Major facilitator Superfamily
MHPFIANA_01768 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHPFIANA_01769 2e-269 KLT Domain of unknown function (DUF4032)
MHPFIANA_01770 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
MHPFIANA_01771 1.1e-130 K LytTr DNA-binding domain
MHPFIANA_01772 3.5e-21 T GHKL domain
MHPFIANA_01773 3.7e-172 T GHKL domain
MHPFIANA_01774 2e-72
MHPFIANA_01775 8.4e-217 clcA_2 P Voltage gated chloride channel
MHPFIANA_01776 5.2e-48 S Psort location Cytoplasmic, score
MHPFIANA_01777 3.8e-137
MHPFIANA_01778 7.2e-178 3.4.22.70 M Sortase family
MHPFIANA_01779 3.2e-268 M LPXTG-motif cell wall anchor domain protein
MHPFIANA_01780 0.0 S LPXTG-motif cell wall anchor domain protein
MHPFIANA_01781 1.3e-72 S GtrA-like protein
MHPFIANA_01782 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
MHPFIANA_01783 3.2e-113 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
MHPFIANA_01784 2.1e-81 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
MHPFIANA_01785 1.1e-113 vex2 V ABC transporter, ATP-binding protein
MHPFIANA_01786 4.5e-214 vex1 V Efflux ABC transporter, permease protein
MHPFIANA_01787 2.9e-241 vex3 V ABC transporter permease
MHPFIANA_01788 1.8e-24 G Major facilitator Superfamily
MHPFIANA_01789 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
MHPFIANA_01790 2.7e-188 lacR K Transcriptional regulator, LacI family
MHPFIANA_01791 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
MHPFIANA_01792 4e-167 dapA 4.1.2.28, 4.3.3.7 EM Dihydrodipicolinate synthetase family
MHPFIANA_01793 4.3e-160 S Amidohydrolase
MHPFIANA_01794 4.9e-145 IQ KR domain
MHPFIANA_01795 6.8e-245 4.2.1.68 M Enolase C-terminal domain-like
MHPFIANA_01796 4.4e-266 G Bacterial extracellular solute-binding protein
MHPFIANA_01797 3.3e-175 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_01798 1.2e-155 P Binding-protein-dependent transport system inner membrane component
MHPFIANA_01799 6e-191 K Bacterial regulatory proteins, lacI family
MHPFIANA_01800 2.3e-53 lacZ5 3.2.1.23 G beta-galactosidase activity
MHPFIANA_01801 1.2e-263 G Bacterial extracellular solute-binding protein
MHPFIANA_01802 6.1e-132 K helix_turn _helix lactose operon repressor
MHPFIANA_01803 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MHPFIANA_01804 2.9e-168 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01805 7.6e-151 G ABC transporter permease
MHPFIANA_01806 3.8e-12 S Psort location Extracellular, score 8.82
MHPFIANA_01807 0.0 trxB1 1.8.1.9 C Thioredoxin domain
MHPFIANA_01808 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MHPFIANA_01809 1.2e-48 I alpha/beta hydrolase fold
MHPFIANA_01810 1.5e-71 I alpha/beta hydrolase fold
MHPFIANA_01811 1.1e-30 I alpha/beta hydrolase fold
MHPFIANA_01812 2.8e-145 cobB2 K Sir2 family
MHPFIANA_01813 2.6e-233 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
MHPFIANA_01814 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MHPFIANA_01815 8.8e-159 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01816 1.2e-158 G Binding-protein-dependent transport system inner membrane component
MHPFIANA_01817 1.5e-244 msmE7 G Bacterial extracellular solute-binding protein
MHPFIANA_01818 1.5e-230 nagC GK ROK family
MHPFIANA_01819 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
MHPFIANA_01820 2.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHPFIANA_01821 0.0 yjcE P Sodium/hydrogen exchanger family
MHPFIANA_01822 1.2e-154 ypfH S Phospholipase/Carboxylesterase
MHPFIANA_01823 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
MHPFIANA_01824 3.4e-28
MHPFIANA_01826 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
MHPFIANA_01827 0.0 KLT Protein tyrosine kinase
MHPFIANA_01828 7.5e-151 O Thioredoxin
MHPFIANA_01830 2.1e-197 S G5
MHPFIANA_01831 1.7e-165 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHPFIANA_01832 9.6e-169 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHPFIANA_01833 2.6e-109 S LytR cell envelope-related transcriptional attenuator
MHPFIANA_01834 6.5e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
MHPFIANA_01835 1.8e-121 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
MHPFIANA_01836 0.0 M Conserved repeat domain
MHPFIANA_01837 2.1e-305 murJ KLT MviN-like protein
MHPFIANA_01838 0.0 murJ KLT MviN-like protein
MHPFIANA_01839 4e-13 S Domain of unknown function (DUF4143)
MHPFIANA_01840 4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
MHPFIANA_01841 9.1e-14 S Psort location Extracellular, score 8.82
MHPFIANA_01842 3.1e-181 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHPFIANA_01843 6.8e-203 parB K Belongs to the ParB family
MHPFIANA_01844 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
MHPFIANA_01845 7.6e-125 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MHPFIANA_01846 8e-91 jag S Putative single-stranded nucleic acids-binding domain
MHPFIANA_01847 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
MHPFIANA_01848 1.5e-43 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHPFIANA_01849 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MHPFIANA_01850 1.2e-49 L Initiator Replication protein
MHPFIANA_01854 5.2e-56 L Psort location Cytoplasmic, score 8.96

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)