ORF_ID e_value Gene_name EC_number CAZy COGs Description
GKHACAHP_00001 2.2e-136 S double-stranded DNA endodeoxyribonuclease activity
GKHACAHP_00002 2.1e-304 hsdM 2.1.1.72 V type I restriction-modification system
GKHACAHP_00003 3.5e-124 S Protein conserved in bacteria
GKHACAHP_00004 2.9e-188 S KAP family P-loop domain
GKHACAHP_00005 1.3e-88 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
GKHACAHP_00006 1.7e-12
GKHACAHP_00007 2.4e-133 L Reverse transcriptase (RNA-dependent DNA polymerase)
GKHACAHP_00008 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
GKHACAHP_00010 3.9e-131 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GKHACAHP_00011 6.8e-212 MA20_36090 S Protein of unknown function (DUF2974)
GKHACAHP_00012 2.6e-104 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKHACAHP_00013 1.1e-153 5.2.1.8 G hydrolase
GKHACAHP_00014 1.3e-26 P Hemerythrin HHE cation binding domain protein
GKHACAHP_00015 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
GKHACAHP_00016 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GKHACAHP_00017 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
GKHACAHP_00018 5.2e-175 S hydrolase
GKHACAHP_00019 8.4e-23
GKHACAHP_00020 3.7e-137 M LysM domain
GKHACAHP_00021 2.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GKHACAHP_00022 3.7e-14
GKHACAHP_00023 8.7e-13
GKHACAHP_00024 8.1e-233 mntH P H( )-stimulated, divalent metal cation uptake system
GKHACAHP_00025 1.1e-33 XK27_12190 S protein conserved in bacteria
GKHACAHP_00027 2.5e-87 bioY S biotin synthase
GKHACAHP_00028 1.7e-251 yegQ O Peptidase U32
GKHACAHP_00029 9.8e-177 yegQ O Peptidase U32
GKHACAHP_00031 3e-67 ytxH S General stress protein
GKHACAHP_00032 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GKHACAHP_00033 1.2e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GKHACAHP_00034 2.2e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GKHACAHP_00035 2.2e-41 pspC KT PspC domain
GKHACAHP_00036 0.0 yhgF K Transcriptional accessory protein
GKHACAHP_00038 1e-154 XK27_03015 S permease
GKHACAHP_00039 2.2e-148 ycgQ S TIGR03943 family
GKHACAHP_00040 1.9e-284 sulP P Sulfate permease and related transporters (MFS superfamily)
GKHACAHP_00041 2.9e-100
GKHACAHP_00042 1.4e-110 estA E GDSL-like Lipase/Acylhydrolase
GKHACAHP_00043 4.3e-96 S CAAX protease self-immunity
GKHACAHP_00044 5e-52
GKHACAHP_00046 2.4e-62 yqeB S Pyrimidine dimer DNA glycosylase
GKHACAHP_00047 2.4e-60 S Protein of unknown function (DUF1722)
GKHACAHP_00048 6.5e-19 M Bacterial lipoprotein
GKHACAHP_00049 2.2e-09
GKHACAHP_00050 1.7e-126 V CAAX protease self-immunity
GKHACAHP_00051 1.8e-45
GKHACAHP_00052 1.3e-73 K TetR family transcriptional regulator
GKHACAHP_00053 1.1e-80 Q Methyltransferase domain
GKHACAHP_00054 1.6e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKHACAHP_00055 1.3e-174 acoB C dehydrogenase E1 component
GKHACAHP_00056 2.8e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
GKHACAHP_00057 1.3e-174 pdhD 1.8.1.4 C Dehydrogenase
GKHACAHP_00058 3.3e-08 K CsbD-like
GKHACAHP_00059 3.3e-08 K CsbD-like
GKHACAHP_00060 7.7e-68 S Asp23 family, cell envelope-related function
GKHACAHP_00061 1.5e-22 S Small integral membrane protein
GKHACAHP_00062 4.7e-97
GKHACAHP_00063 5.5e-31 S Membrane
GKHACAHP_00064 4.7e-172 S Domain of unknown function (DUF389)
GKHACAHP_00065 2.8e-157 yegS 2.7.1.107 I Diacylglycerol kinase
GKHACAHP_00066 3.9e-122 ybbA S Putative esterase
GKHACAHP_00067 1.3e-174 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GKHACAHP_00068 2.9e-134 fecE 3.6.3.34 HP ABC transporter
GKHACAHP_00069 5.1e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GKHACAHP_00070 2e-119 V CAAX protease self-immunity
GKHACAHP_00071 9.9e-152 S Domain of unknown function (DUF4300)
GKHACAHP_00072 3.9e-19 S Domain of unknown function (DUF4767)
GKHACAHP_00074 8.1e-114 cutC P Participates in the control of copper homeostasis
GKHACAHP_00075 2e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
GKHACAHP_00076 3e-148 yitS S EDD domain protein, DegV family
GKHACAHP_00077 7e-204 yeaN P transporter
GKHACAHP_00078 2.1e-129 S Domain of unknown function (DUF4336)
GKHACAHP_00079 1.8e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GKHACAHP_00080 1.1e-117
GKHACAHP_00081 1.3e-80 3.1.3.16 S Protein of unknown function (DUF1643)
GKHACAHP_00082 4.9e-24 L PFAM Integrase catalytic region
GKHACAHP_00084 1.8e-120 S CAAX amino terminal protease family protein
GKHACAHP_00085 9.5e-53 K Transcriptional regulator
GKHACAHP_00086 5.4e-33 S Protein of unknown function (DUF1648)
GKHACAHP_00087 1.8e-255 6.1.1.6 S Psort location CytoplasmicMembrane, score
GKHACAHP_00088 1.1e-130 ecsA V AAA domain, putative AbiEii toxin, Type IV TA system
GKHACAHP_00089 2.7e-106 K Transcriptional regulator
GKHACAHP_00090 4e-96
GKHACAHP_00091 3.8e-55 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKHACAHP_00092 1.2e-18 S alpha beta
GKHACAHP_00093 1.5e-52 K TfoX N-terminal domain
GKHACAHP_00094 6.7e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKHACAHP_00095 2e-97 mip S hydroperoxide reductase activity
GKHACAHP_00096 4.2e-200 I acyl-CoA dehydrogenase
GKHACAHP_00097 4.2e-151 ydiA P C4-dicarboxylate transporter malic acid transport protein
GKHACAHP_00098 7.8e-250 msrR K Transcriptional regulator
GKHACAHP_00099 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
GKHACAHP_00100 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GKHACAHP_00101 8.3e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GKHACAHP_00102 3.2e-151 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
GKHACAHP_00103 4.2e-53 yheA S Belongs to the UPF0342 family
GKHACAHP_00104 2.7e-205 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
GKHACAHP_00105 3.8e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GKHACAHP_00106 5e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GKHACAHP_00107 1.7e-154 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GKHACAHP_00108 4.4e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GKHACAHP_00109 3e-215 ywbD 2.1.1.191 J Methyltransferase
GKHACAHP_00110 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GKHACAHP_00111 4.6e-25 WQ51_00785
GKHACAHP_00112 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GKHACAHP_00113 3.1e-75 yueI S Protein of unknown function (DUF1694)
GKHACAHP_00114 1.4e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GKHACAHP_00115 3.6e-199 yyaQ S YjbR
GKHACAHP_00116 2.4e-181 ccpA K Catabolite control protein A
GKHACAHP_00117 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
GKHACAHP_00118 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
GKHACAHP_00119 1.1e-275 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKHACAHP_00120 6.6e-81 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
GKHACAHP_00121 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GKHACAHP_00122 2e-33 secG U Preprotein translocase subunit SecG
GKHACAHP_00123 2.3e-218 mdtG EGP Major facilitator Superfamily
GKHACAHP_00124 1.3e-94 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GKHACAHP_00125 1.8e-145 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GKHACAHP_00126 3.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GKHACAHP_00127 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GKHACAHP_00128 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GKHACAHP_00129 6.8e-145 licT K antiterminator
GKHACAHP_00130 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GKHACAHP_00131 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
GKHACAHP_00132 1.4e-142 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GKHACAHP_00133 2.4e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GKHACAHP_00134 1.8e-147 I Alpha/beta hydrolase family
GKHACAHP_00135 6.6e-08
GKHACAHP_00136 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
GKHACAHP_00137 4.5e-77 feoA P FeoA domain protein
GKHACAHP_00138 1.7e-128 glnQ 3.6.3.21 E abc transporter atp-binding protein
GKHACAHP_00139 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
GKHACAHP_00140 1e-34 ykuJ S protein conserved in bacteria
GKHACAHP_00141 1.1e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GKHACAHP_00142 0.0 clpE O Belongs to the ClpA ClpB family
GKHACAHP_00143 1.8e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
GKHACAHP_00144 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
GKHACAHP_00145 2.6e-172 S oxidoreductase
GKHACAHP_00146 5.6e-228 murN 2.3.2.16 V FemAB family
GKHACAHP_00147 1.9e-116 M Pfam SNARE associated Golgi protein
GKHACAHP_00148 3.9e-105 S Domain of Unknown Function with PDB structure (DUF3862)
GKHACAHP_00151 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
GKHACAHP_00154 1.4e-15 S Protein of unknown function (DUF2969)
GKHACAHP_00155 2.4e-200 ilvE 2.6.1.42 E Aminotransferase
GKHACAHP_00156 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKHACAHP_00157 4.2e-147 aadK G adenylyltransferase
GKHACAHP_00158 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GKHACAHP_00159 7.4e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GKHACAHP_00160 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
GKHACAHP_00161 2.2e-30 S Domain of unknown function (DUF1912)
GKHACAHP_00162 2.3e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
GKHACAHP_00163 5.8e-250 mmuP E amino acid
GKHACAHP_00164 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
GKHACAHP_00165 4.4e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GKHACAHP_00166 9.7e-22
GKHACAHP_00167 5.8e-91 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GKHACAHP_00168 2.2e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GKHACAHP_00169 3.7e-213 mvaS 2.3.3.10 I synthase
GKHACAHP_00170 2.9e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
GKHACAHP_00171 3e-78 K hmm pf08876
GKHACAHP_00172 5.2e-119 yqfA K protein, Hemolysin III
GKHACAHP_00173 4.1e-29 pspC KT PspC domain protein
GKHACAHP_00174 5.5e-200 S Protein of unknown function (DUF3114)
GKHACAHP_00175 1.5e-161 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GKHACAHP_00176 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GKHACAHP_00177 1.7e-13
GKHACAHP_00178 2.6e-247 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
GKHACAHP_00179 2.6e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
GKHACAHP_00180 0.0 U protein secretion
GKHACAHP_00181 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GKHACAHP_00182 1.1e-24
GKHACAHP_00183 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
GKHACAHP_00184 3.2e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GKHACAHP_00185 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
GKHACAHP_00186 5.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GKHACAHP_00187 4.9e-166 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
GKHACAHP_00188 1e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
GKHACAHP_00189 1e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
GKHACAHP_00190 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GKHACAHP_00191 3e-179 ybdK T ATPase histidine kinase DNA gyrase B HSP90 domain protein
GKHACAHP_00192 1.3e-109 T Response regulator receiver domain protein
GKHACAHP_00193 5.5e-50 T peptidase
GKHACAHP_00194 5.6e-120 E alpha/beta hydrolase fold
GKHACAHP_00196 6.6e-196 ald 1.4.1.1 C Belongs to the AlaDH PNT family
GKHACAHP_00197 2.2e-218 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GKHACAHP_00198 6.1e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GKHACAHP_00199 3.9e-114 S VIT family
GKHACAHP_00200 1.3e-195 yceA S Belongs to the UPF0176 family
GKHACAHP_00201 9.5e-124 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GKHACAHP_00202 1.3e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GKHACAHP_00203 0.0 lmrA V abc transporter atp-binding protein
GKHACAHP_00204 0.0 mdlB V abc transporter atp-binding protein
GKHACAHP_00205 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GKHACAHP_00206 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GKHACAHP_00207 1.4e-202 V permease protein
GKHACAHP_00208 3.1e-122 macB V ABC transporter, ATP-binding protein
GKHACAHP_00209 6.8e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GKHACAHP_00210 1.7e-123 rsmJ 2.1.1.242 J Putative SAM-dependent methyltransferase
GKHACAHP_00211 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
GKHACAHP_00212 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
GKHACAHP_00213 2.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GKHACAHP_00214 3.6e-222 pyrP F uracil Permease
GKHACAHP_00215 1.8e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GKHACAHP_00216 1.1e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GKHACAHP_00217 1.3e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GKHACAHP_00218 4.7e-168 fhuR K transcriptional regulator (lysR family)
GKHACAHP_00220 3.9e-43
GKHACAHP_00221 1.5e-69 K Helix-turn-helix
GKHACAHP_00225 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GKHACAHP_00226 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GKHACAHP_00227 6e-08 uvrX 2.7.7.7 L impB/mucB/samB family
GKHACAHP_00228 7.9e-255 cycA E permease
GKHACAHP_00229 1.7e-38 ynzC S UPF0291 protein
GKHACAHP_00230 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GKHACAHP_00231 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GKHACAHP_00232 4.6e-222 S membrane
GKHACAHP_00233 4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GKHACAHP_00234 3.5e-294 nptA P COG1283 Na phosphate symporter
GKHACAHP_00235 9.8e-112 3.4.17.14, 3.5.1.28 NU amidase activity
GKHACAHP_00236 2.2e-80 S Bacterial inner membrane protein
GKHACAHP_00237 1.9e-144 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
GKHACAHP_00238 1.2e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
GKHACAHP_00239 1.9e-53 glnB K Belongs to the P(II) protein family
GKHACAHP_00240 2.8e-227 amt P Ammonium Transporter
GKHACAHP_00241 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GKHACAHP_00242 1.2e-54 yabA L Involved in initiation control of chromosome replication
GKHACAHP_00243 1.3e-132 yaaT S stage 0 sporulation protein
GKHACAHP_00244 3.9e-159 holB 2.7.7.7 L dna polymerase iii
GKHACAHP_00245 2.3e-108 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GKHACAHP_00247 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GKHACAHP_00248 9.9e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GKHACAHP_00249 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GKHACAHP_00250 1.2e-217 ftsW D Belongs to the SEDS family
GKHACAHP_00251 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GKHACAHP_00252 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GKHACAHP_00253 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GKHACAHP_00254 2.9e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GKHACAHP_00255 3.9e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKHACAHP_00256 3.6e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GKHACAHP_00257 3.4e-121 atpB C it plays a direct role in the translocation of protons across the membrane
GKHACAHP_00258 2.4e-16 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GKHACAHP_00259 3.1e-83 L HNH nucleases
GKHACAHP_00261 0.0 T Histidine kinase
GKHACAHP_00262 9.6e-245 V site-specific DNA-methyltransferase (adenine-specific) activity
GKHACAHP_00263 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GKHACAHP_00264 5.6e-98 F Shikimate kinase
GKHACAHP_00265 6.5e-99 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
GKHACAHP_00266 2.6e-103 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GKHACAHP_00269 3e-14 coiA 3.6.4.12 S Competence protein
GKHACAHP_00270 8.3e-15 T peptidase
GKHACAHP_00271 3.1e-148 rarD S Transporter
GKHACAHP_00272 2e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GKHACAHP_00273 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
GKHACAHP_00274 1.4e-132 yxkH G deacetylase
GKHACAHP_00275 8.2e-202 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
GKHACAHP_00276 8.7e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
GKHACAHP_00277 7.8e-219 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GKHACAHP_00278 3.1e-184 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GKHACAHP_00279 2.6e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
GKHACAHP_00280 1.2e-140 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GKHACAHP_00281 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
GKHACAHP_00282 1.5e-14
GKHACAHP_00283 4.6e-228 2.7.13.3 T GHKL domain
GKHACAHP_00284 2.4e-133 agrA KT phosphorelay signal transduction system
GKHACAHP_00286 3e-136 agrA KT response regulator
GKHACAHP_00287 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
GKHACAHP_00288 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GKHACAHP_00289 2.7e-85 yxjI S LURP-one-related
GKHACAHP_00290 6.2e-165 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
GKHACAHP_00291 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
GKHACAHP_00292 3.8e-213 oxlT P COG0477 Permeases of the major facilitator superfamily
GKHACAHP_00293 0.0 pepF E oligoendopeptidase F
GKHACAHP_00294 7.2e-175 coiA 3.6.4.12 S Competence protein
GKHACAHP_00295 4.4e-256 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GKHACAHP_00296 4.2e-106 S CAAX amino terminal protease family protein
GKHACAHP_00297 4.7e-168 K transcriptional regulator (lysR family)
GKHACAHP_00298 3.8e-159 S reductase
GKHACAHP_00299 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GKHACAHP_00303 3.1e-187 phoH T phosphate starvation-inducible protein PhoH
GKHACAHP_00304 7.7e-124 sip M LysM domain protein
GKHACAHP_00305 3.7e-34 yozE S Belongs to the UPF0346 family
GKHACAHP_00306 6.5e-159 cvfB S Protein conserved in bacteria
GKHACAHP_00307 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GKHACAHP_00308 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GKHACAHP_00309 1.3e-216 sptS 2.7.13.3 T Histidine kinase
GKHACAHP_00310 2.9e-117 T response regulator
GKHACAHP_00311 3.7e-111 2.7.6.5 S Region found in RelA / SpoT proteins
GKHACAHP_00312 1.9e-112 K Acetyltransferase (GNAT) family
GKHACAHP_00313 0.0 lmrA2 V abc transporter atp-binding protein
GKHACAHP_00314 0.0 lmrA1 V abc transporter atp-binding protein
GKHACAHP_00315 4.1e-72 K DNA-binding transcription factor activity
GKHACAHP_00316 4.6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
GKHACAHP_00317 1.7e-280 S Psort location CytoplasmicMembrane, score
GKHACAHP_00318 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
GKHACAHP_00319 5.5e-211 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
GKHACAHP_00320 3.1e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
GKHACAHP_00321 1.3e-26 U response to pH
GKHACAHP_00322 0.0 yfmR S abc transporter atp-binding protein
GKHACAHP_00323 9.6e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GKHACAHP_00324 3.9e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GKHACAHP_00325 9.6e-147 XK27_08360 S EDD domain protein, DegV family
GKHACAHP_00326 5e-63 WQ51_03320 S cog cog4835
GKHACAHP_00327 9.4e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GKHACAHP_00328 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GKHACAHP_00329 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
GKHACAHP_00330 2.4e-90 2.3.1.128 K acetyltransferase
GKHACAHP_00331 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GKHACAHP_00332 9.7e-291 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GKHACAHP_00333 9.7e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GKHACAHP_00334 3.5e-208 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
GKHACAHP_00336 4.3e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GKHACAHP_00337 4.6e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GKHACAHP_00338 0.0 fruA 2.7.1.202 G phosphotransferase system
GKHACAHP_00339 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GKHACAHP_00340 1.4e-112 fruR K transcriptional
GKHACAHP_00341 1.9e-207 rny D Endoribonuclease that initiates mRNA decay
GKHACAHP_00342 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GKHACAHP_00343 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GKHACAHP_00344 3.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GKHACAHP_00345 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GKHACAHP_00346 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GKHACAHP_00347 1.6e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GKHACAHP_00348 1.3e-232 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GKHACAHP_00349 1.1e-125 IQ reductase
GKHACAHP_00350 3.3e-161 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
GKHACAHP_00351 9.9e-172 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
GKHACAHP_00352 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKHACAHP_00353 1.1e-170 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GKHACAHP_00354 5.2e-72 marR K Transcriptional regulator, MarR family
GKHACAHP_00355 3.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
GKHACAHP_00356 8.1e-114 S HAD hydrolase, family IA, variant 3
GKHACAHP_00357 3.1e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
GKHACAHP_00358 8.8e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
GKHACAHP_00359 4.5e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GKHACAHP_00360 5.4e-136 recX 2.4.1.337 GT4 S Regulatory protein RecX
GKHACAHP_00361 7.8e-102 ygaC J Belongs to the UPF0374 family
GKHACAHP_00362 1.5e-104 S Domain of unknown function (DUF1803)
GKHACAHP_00363 3.9e-165 ppaC 3.6.1.1 C inorganic pyrophosphatase
GKHACAHP_00364 0.0 3.5.1.28 NU amidase activity
GKHACAHP_00365 0.0 lpdA 1.8.1.4 C Dehydrogenase
GKHACAHP_00366 5.8e-210 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GKHACAHP_00367 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GKHACAHP_00368 8.6e-184 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
GKHACAHP_00369 2.5e-207 hpk9 2.7.13.3 T protein histidine kinase activity
GKHACAHP_00370 2.9e-227 2.7.13.3 T protein histidine kinase activity
GKHACAHP_00371 0.0 S the current gene model (or a revised gene model) may contain a frame shift
GKHACAHP_00372 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GKHACAHP_00373 2.9e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GKHACAHP_00374 2.4e-215 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GKHACAHP_00375 1.5e-247 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
GKHACAHP_00376 3.6e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
GKHACAHP_00377 1.1e-155 rssA S Phospholipase, patatin family
GKHACAHP_00378 4.8e-103 estA E Lysophospholipase L1 and related esterases
GKHACAHP_00379 5.2e-287 S unusual protein kinase
GKHACAHP_00380 4.9e-39 S granule-associated protein
GKHACAHP_00381 4.4e-285 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GKHACAHP_00382 2.7e-197 S hmm pf01594
GKHACAHP_00383 8.1e-108 G Belongs to the phosphoglycerate mutase family
GKHACAHP_00384 1.4e-107 G Belongs to the phosphoglycerate mutase family
GKHACAHP_00385 1.4e-107 pgm G Belongs to the phosphoglycerate mutase family
GKHACAHP_00386 1.1e-152 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GKHACAHP_00388 5.7e-181 wbbI M transferase activity, transferring glycosyl groups
GKHACAHP_00389 1.4e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
GKHACAHP_00390 7.5e-245 epsU S Polysaccharide biosynthesis protein
GKHACAHP_00391 6.3e-173
GKHACAHP_00392 1.9e-154 M Glycosyltransferase like family 2
GKHACAHP_00393 2.3e-128 M Glycosyltransferase, group 2 family protein
GKHACAHP_00394 2.1e-117 Z012_10770 M Domain of unknown function (DUF1919)
GKHACAHP_00395 9.2e-189 sacB GT2,GT4 M Stealth protein CR3, conserved region 3
GKHACAHP_00396 2.6e-211 wcoF M Glycosyltransferase, group 1 family protein
GKHACAHP_00397 9.7e-222 rgpAc GT4 M group 1 family protein
GKHACAHP_00398 7.2e-253 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
GKHACAHP_00399 3.4e-116 cpsD D COG0489 ATPases involved in chromosome partitioning
GKHACAHP_00400 3.5e-110 cps4C M biosynthesis protein
GKHACAHP_00401 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
GKHACAHP_00402 4.7e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
GKHACAHP_00403 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
GKHACAHP_00404 6.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
GKHACAHP_00405 4.5e-177 clcA_2 P Chloride transporter, ClC family
GKHACAHP_00406 1.1e-50 S LemA family
GKHACAHP_00407 1.9e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GKHACAHP_00408 1.1e-95 S Protein of unknown function (DUF1697)
GKHACAHP_00409 5.1e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GKHACAHP_00410 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GKHACAHP_00411 2.5e-253 V Glucan-binding protein C
GKHACAHP_00412 5.5e-226 V Glucan-binding protein C
GKHACAHP_00413 3.6e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
GKHACAHP_00414 2.1e-271 pepV 3.5.1.18 E Dipeptidase
GKHACAHP_00415 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
GKHACAHP_00416 5.5e-92 yybC
GKHACAHP_00417 1.9e-83 XK27_03610 K Gnat family
GKHACAHP_00418 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GKHACAHP_00419 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GKHACAHP_00420 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GKHACAHP_00421 1.6e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GKHACAHP_00422 2.5e-17 M LysM domain
GKHACAHP_00423 8.6e-87 ebsA S Family of unknown function (DUF5322)
GKHACAHP_00424 3.1e-231 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GKHACAHP_00425 8.5e-24 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GKHACAHP_00426 6e-307 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
GKHACAHP_00427 4.8e-117 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
GKHACAHP_00428 0.0 L DEAD-like helicases superfamily
GKHACAHP_00429 3.1e-107 S Abortive infection C-terminus
GKHACAHP_00430 3.2e-219
GKHACAHP_00431 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GKHACAHP_00432 2.7e-157 yvgN C reductase
GKHACAHP_00433 1.9e-30 XK27_10490
GKHACAHP_00434 4e-40 DJ nuclease activity
GKHACAHP_00435 1.1e-100 yoaK S Protein of unknown function (DUF1275)
GKHACAHP_00436 6.6e-108 drgA C nitroreductase
GKHACAHP_00437 1.9e-121 T Xre family transcriptional regulator
GKHACAHP_00438 1.7e-130 T PhoQ Sensor
GKHACAHP_00439 9.4e-45 S Domain of unknown function (DUF4352)
GKHACAHP_00440 9.9e-127 S ABC-2 family transporter protein
GKHACAHP_00441 4.1e-167 bcrA V abc transporter atp-binding protein
GKHACAHP_00442 1.2e-225 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKHACAHP_00443 9.2e-153 E Alpha/beta hydrolase of unknown function (DUF915)
GKHACAHP_00444 8.9e-75 ywnA K Transcriptional regulator
GKHACAHP_00445 8.5e-151 1.13.11.2 S glyoxalase
GKHACAHP_00446 1.2e-100 XK27_02070 S nitroreductase
GKHACAHP_00447 6.8e-170 ydhF S Aldo keto reductase
GKHACAHP_00448 1.8e-96 K WHG domain
GKHACAHP_00449 1.6e-123 V abc transporter atp-binding protein
GKHACAHP_00450 3.6e-205 P FtsX-like permease family
GKHACAHP_00451 8.2e-15 XK27_10130
GKHACAHP_00453 1.5e-42 S Sugar efflux transporter for intercellular exchange
GKHACAHP_00454 1.1e-81 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
GKHACAHP_00455 0.0 S dextransucrase activity
GKHACAHP_00456 2.1e-215 yfnA E amino acid
GKHACAHP_00457 2.6e-50 XK27_01300 P Protein conserved in bacteria
GKHACAHP_00458 2.5e-84 S Carbohydrate-binding domain-containing protein Cthe_2159
GKHACAHP_00459 5.9e-15 csbD K CsbD-like
GKHACAHP_00460 6e-101 S Protein of unknown function (DUF421)
GKHACAHP_00461 2e-58 S Protein of unknown function (DUF3290)
GKHACAHP_00462 1.9e-180 manA 5.3.1.8 G mannose-6-phosphate isomerase
GKHACAHP_00463 6.4e-230 brnQ E Component of the transport system for branched-chain amino acids
GKHACAHP_00464 5.3e-186 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GKHACAHP_00466 4.6e-244 norM V Multidrug efflux pump
GKHACAHP_00467 4.9e-59 pdxH S pyridoxamine 5'-phosphate oxidase
GKHACAHP_00468 8.5e-224 pbuX F xanthine permease
GKHACAHP_00469 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GKHACAHP_00470 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKHACAHP_00471 5.3e-149 T Histidine kinase
GKHACAHP_00472 2.5e-130 macB2 V ABC transporter, ATP-binding protein
GKHACAHP_00473 0.0 V ABC transporter (permease)
GKHACAHP_00474 6.1e-93 XK27_05000 S metal cluster binding
GKHACAHP_00475 2.2e-29 liaI KT membrane
GKHACAHP_00476 1.4e-15 liaI KT membrane
GKHACAHP_00477 4.5e-155 XK27_09825 V abc transporter atp-binding protein
GKHACAHP_00478 3.1e-117 yvfS V Transporter
GKHACAHP_00479 2.2e-81 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
GKHACAHP_00480 2.3e-165 yocS S Transporter
GKHACAHP_00483 8.2e-157 XK27_09825 V 'abc transporter, ATP-binding protein
GKHACAHP_00484 2.8e-134 yvfS V ABC-2 type transporter
GKHACAHP_00485 4.6e-186 desK 2.7.13.3 T Histidine kinase
GKHACAHP_00486 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKHACAHP_00487 1.1e-186 S abc transporter atp-binding protein
GKHACAHP_00488 5.3e-142 S ABC-2 family transporter protein
GKHACAHP_00489 1.9e-141 S ABC-2 family transporter protein
GKHACAHP_00490 1.4e-75 K Acetyltransferase (GNAT) domain
GKHACAHP_00491 0.0 prtA 3.2.1.23 O Belongs to the peptidase S8 family
GKHACAHP_00492 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GKHACAHP_00493 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GKHACAHP_00494 5.3e-234 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GKHACAHP_00495 1.7e-235 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
GKHACAHP_00497 3e-60 divIC D Septum formation initiator
GKHACAHP_00498 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GKHACAHP_00499 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GKHACAHP_00500 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GKHACAHP_00501 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GKHACAHP_00502 1.1e-29 yyzM S Protein conserved in bacteria
GKHACAHP_00503 2.7e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GKHACAHP_00504 1.3e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GKHACAHP_00505 1.4e-133 parB K Belongs to the ParB family
GKHACAHP_00506 5.1e-205 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
GKHACAHP_00507 8e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GKHACAHP_00508 6.2e-120 yoaK S Protein of unknown function (DUF1275)
GKHACAHP_00512 0.0 XK27_10405 S Bacterial membrane protein YfhO
GKHACAHP_00513 3.3e-305 ybiT S abc transporter atp-binding protein
GKHACAHP_00514 7.1e-153 yvjA S membrane
GKHACAHP_00515 4.5e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
GKHACAHP_00516 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GKHACAHP_00517 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GKHACAHP_00518 4.9e-58 yaaA S S4 domain protein YaaA
GKHACAHP_00519 3.5e-230 ymfF S Peptidase M16
GKHACAHP_00520 5.9e-233 ymfH S Peptidase M16
GKHACAHP_00521 1.4e-129 S sequence-specific DNA binding
GKHACAHP_00522 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GKHACAHP_00523 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKHACAHP_00524 6.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKHACAHP_00525 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GKHACAHP_00526 1e-70 lytE M LysM domain protein
GKHACAHP_00527 8.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
GKHACAHP_00528 0.0 S Bacterial membrane protein, YfhO
GKHACAHP_00529 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GKHACAHP_00530 5.4e-99 yvbG U UPF0056 membrane protein
GKHACAHP_00531 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GKHACAHP_00532 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GKHACAHP_00533 2.2e-73 rplI J binds to the 23S rRNA
GKHACAHP_00534 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GKHACAHP_00535 1.8e-47 veg S Biofilm formation stimulator VEG
GKHACAHP_00536 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GKHACAHP_00537 0.0 ctpC 3.6.3.10, 3.6.3.4 P p-ATPase superfamily P-type ATPase copper transporter
GKHACAHP_00538 2.6e-40
GKHACAHP_00539 1.6e-105 L Transposase
GKHACAHP_00540 3.8e-52 S membrane protein of uknown function UCP014873
GKHACAHP_00541 3e-31 int L DNA integration
GKHACAHP_00542 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
GKHACAHP_00543 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GKHACAHP_00544 5.1e-22 K Transcriptional
GKHACAHP_00546 5.4e-153 degV S DegV family
GKHACAHP_00547 2.7e-91 yacP S RNA-binding protein containing a PIN domain
GKHACAHP_00548 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKHACAHP_00550 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GKHACAHP_00551 9e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GKHACAHP_00553 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
GKHACAHP_00554 1.4e-139 S SseB protein N-terminal domain
GKHACAHP_00555 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GKHACAHP_00556 2.6e-225 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GKHACAHP_00557 4.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GKHACAHP_00558 0.0 clpC O Belongs to the ClpA ClpB family
GKHACAHP_00559 1.8e-75 ctsR K Belongs to the CtsR family
GKHACAHP_00560 1.6e-82 S Putative small multi-drug export protein
GKHACAHP_00561 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GKHACAHP_00562 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
GKHACAHP_00563 3.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
GKHACAHP_00564 1.3e-287 ahpF O alkyl hydroperoxide reductase
GKHACAHP_00566 3.6e-94 S reductase
GKHACAHP_00567 3.9e-72 badR K Transcriptional regulator, marr family
GKHACAHP_00568 1.2e-35 XK27_02060 S Transglycosylase associated protein
GKHACAHP_00569 5.6e-236 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
GKHACAHP_00570 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKHACAHP_00571 3.6e-49 qacC P COG2076 Membrane transporters of cations and cationic drugs
GKHACAHP_00572 1e-75 K Transcriptional
GKHACAHP_00573 2.7e-74
GKHACAHP_00574 7e-228 L Replication initiation factor
GKHACAHP_00575 3.4e-67
GKHACAHP_00576 3.5e-28 S Domain of unknown function (DUF3173)
GKHACAHP_00577 4.2e-198 L Belongs to the 'phage' integrase family
GKHACAHP_00581 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
GKHACAHP_00582 1.6e-194 ylbM S Belongs to the UPF0348 family
GKHACAHP_00583 1.9e-138 yqeM Q Methyltransferase domain protein
GKHACAHP_00584 2e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GKHACAHP_00585 4.1e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
GKHACAHP_00586 4.5e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GKHACAHP_00587 3.8e-48 yhbY J RNA-binding protein
GKHACAHP_00588 7.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GKHACAHP_00589 1.4e-98 yqeG S hydrolase of the HAD superfamily
GKHACAHP_00590 2.3e-154 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GKHACAHP_00591 4.6e-64
GKHACAHP_00592 5.3e-216 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GKHACAHP_00593 3.2e-57
GKHACAHP_00594 1.7e-40 celC 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
GKHACAHP_00595 2.9e-279 celR 2.7.1.194, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
GKHACAHP_00596 1.6e-46 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIB subunit
GKHACAHP_00597 4.1e-283 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GKHACAHP_00599 2.3e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKHACAHP_00600 2.2e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GKHACAHP_00601 2.6e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GKHACAHP_00602 9.6e-235 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
GKHACAHP_00603 5.4e-189 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
GKHACAHP_00604 8.2e-157 H COG0463 Glycosyltransferases involved in cell wall biogenesis
GKHACAHP_00605 6.7e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
GKHACAHP_00606 2.6e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GKHACAHP_00607 2e-100 pncA Q isochorismatase
GKHACAHP_00608 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GKHACAHP_00615 2.6e-10
GKHACAHP_00621 2e-96 mreC M Involved in formation and maintenance of cell shape
GKHACAHP_00622 7.9e-83 mreD M rod shape-determining protein MreD
GKHACAHP_00623 1.1e-84 usp 3.5.1.28 CBM50 S CHAP domain
GKHACAHP_00624 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKHACAHP_00625 9.4e-217 araT 2.6.1.1 E Aminotransferase
GKHACAHP_00626 1e-139 recO L Involved in DNA repair and RecF pathway recombination
GKHACAHP_00627 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GKHACAHP_00628 2.4e-29 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GKHACAHP_00629 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GKHACAHP_00630 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GKHACAHP_00631 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GKHACAHP_00632 7.2e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GKHACAHP_00633 1.2e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GKHACAHP_00634 5.6e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GKHACAHP_00635 1.1e-153 S CHAP domain
GKHACAHP_00637 3.6e-238 purD 6.3.4.13 F Belongs to the GARS family
GKHACAHP_00638 3.8e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GKHACAHP_00639 2.3e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GKHACAHP_00640 1.2e-169 1.1.1.169 H Ketopantoate reductase
GKHACAHP_00641 3.3e-33
GKHACAHP_00642 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GKHACAHP_00643 2.1e-230 XK27_09615 C reductase
GKHACAHP_00644 3.1e-107 XK27_09620 S FMN reductase (NADPH) activity
GKHACAHP_00645 5e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
GKHACAHP_00646 8.7e-74 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GKHACAHP_00647 1.4e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GKHACAHP_00648 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
GKHACAHP_00649 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
GKHACAHP_00650 1.2e-50 S Protein of unknown function (DUF3397)
GKHACAHP_00651 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GKHACAHP_00652 1.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GKHACAHP_00653 0.0 amiA E ABC transporter, substrate-binding protein, family 5
GKHACAHP_00654 6.7e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GKHACAHP_00655 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
GKHACAHP_00656 1.2e-150 hpk9 2.7.13.3 T protein histidine kinase activity
GKHACAHP_00657 1.9e-207 hpk9 2.7.13.3 T protein histidine kinase activity
GKHACAHP_00658 6.8e-224 fasC 2.7.13.3 T protein histidine kinase activity
GKHACAHP_00659 7.2e-130 fasA KT Response regulator of the LytR AlgR family
GKHACAHP_00660 1.7e-229 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GKHACAHP_00661 7.8e-263 argH 4.3.2.1 E Argininosuccinate lyase
GKHACAHP_00662 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GKHACAHP_00663 6.3e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKHACAHP_00664 3.2e-168 jag S RNA-binding protein
GKHACAHP_00665 4.5e-98 K Transcriptional regulator
GKHACAHP_00666 1.7e-99 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
GKHACAHP_00667 3.4e-14 rpmH J Ribosomal protein L34
GKHACAHP_00668 1.4e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GKHACAHP_00669 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GKHACAHP_00670 1.2e-222 G COG0457 FOG TPR repeat
GKHACAHP_00671 7.3e-177 yubA S permease
GKHACAHP_00672 1.9e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
GKHACAHP_00673 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GKHACAHP_00674 3.2e-124 ftsE D cell division ATP-binding protein FtsE
GKHACAHP_00675 1.6e-182 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GKHACAHP_00676 1.9e-203 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GKHACAHP_00677 1.4e-153 yjjH S Calcineurin-like phosphoesterase
GKHACAHP_00678 4.2e-130 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
GKHACAHP_00679 0.0 pacL 3.6.3.8 P cation transport ATPase
GKHACAHP_00680 5.3e-68 ywiB S Domain of unknown function (DUF1934)
GKHACAHP_00681 5.4e-145 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
GKHACAHP_00682 7.8e-146 yidA S hydrolases of the HAD superfamily
GKHACAHP_00683 2.3e-226 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
GKHACAHP_00684 6.7e-57 S Protein of unknown function (DUF454)
GKHACAHP_00685 1.7e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
GKHACAHP_00686 3.6e-228 vicK 2.7.13.3 T Histidine kinase
GKHACAHP_00687 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKHACAHP_00688 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
GKHACAHP_00689 1.1e-78 hmpT S cog cog4720
GKHACAHP_00690 4.5e-135 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
GKHACAHP_00691 3.8e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GKHACAHP_00692 8e-189 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GKHACAHP_00694 6e-303 dnaK O Heat shock 70 kDa protein
GKHACAHP_00695 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GKHACAHP_00696 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GKHACAHP_00697 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
GKHACAHP_00698 4.7e-135 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GKHACAHP_00699 1.9e-132 ais G Phosphoglycerate mutase
GKHACAHP_00700 2.3e-243 XK27_08635 S UPF0210 protein
GKHACAHP_00701 1e-38 gcvR T UPF0237 protein
GKHACAHP_00702 1.3e-232 capA M Bacterial capsule synthesis protein
GKHACAHP_00703 4.6e-149 srtB 3.4.22.70 S Sortase family
GKHACAHP_00705 1.5e-29 K Helix-turn-helix domain
GKHACAHP_00706 1.9e-16
GKHACAHP_00707 4.5e-55 cadC K Bacterial regulatory protein, arsR family
GKHACAHP_00708 1.5e-101 cadD P cadmium resistance
GKHACAHP_00709 1.6e-112 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
GKHACAHP_00710 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
GKHACAHP_00711 0.0
GKHACAHP_00712 1.5e-07
GKHACAHP_00715 1.8e-115 nudL L hydrolase
GKHACAHP_00716 1.6e-52 K transcriptional regulator, PadR family
GKHACAHP_00717 2.3e-70 XK27_06920 S Protein of unknown function (DUF1700)
GKHACAHP_00718 1.1e-105 S Putative adhesin
GKHACAHP_00719 1.6e-159 XK27_06930 V domain protein
GKHACAHP_00720 9.9e-97 XK27_06935 K transcriptional regulator
GKHACAHP_00721 4.1e-54 ypaA M Membrane
GKHACAHP_00722 1.9e-10
GKHACAHP_00723 5e-227 vncS 2.7.13.3 T Histidine kinase
GKHACAHP_00724 2.2e-114 K Response regulator receiver domain protein
GKHACAHP_00725 2.6e-234 vex3 V Efflux ABC transporter, permease protein
GKHACAHP_00726 1.7e-108 vex2 V abc transporter atp-binding protein
GKHACAHP_00727 1.3e-179 vex1 V Efflux ABC transporter, permease protein
GKHACAHP_00728 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
GKHACAHP_00730 3.8e-196 gldA 1.1.1.6 C glycerol dehydrogenase
GKHACAHP_00731 1.8e-176 XK27_10475 S oxidoreductase
GKHACAHP_00732 1.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
GKHACAHP_00733 3.8e-94 dhaL 2.7.1.121 S Dihydroxyacetone kinase
GKHACAHP_00734 1.4e-176 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
GKHACAHP_00735 7.7e-225 thrE K Psort location CytoplasmicMembrane, score
GKHACAHP_00736 3.6e-26 M Putative cell wall binding repeat
GKHACAHP_00737 0.0 M Putative cell wall binding repeat
GKHACAHP_00738 4.1e-34 S Immunity protein 41
GKHACAHP_00739 0.0 pepO 3.4.24.71 O Peptidase family M13
GKHACAHP_00740 9e-08 S Enterocin A Immunity
GKHACAHP_00741 1.4e-192 mccF V LD-carboxypeptidase
GKHACAHP_00742 1.8e-14 S integral membrane protein
GKHACAHP_00743 1.1e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
GKHACAHP_00744 1.7e-107 yhfC S Putative membrane peptidase family (DUF2324)
GKHACAHP_00746 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GKHACAHP_00748 3.3e-66
GKHACAHP_00749 1.2e-235 S dextransucrase activity
GKHACAHP_00750 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GKHACAHP_00751 0.0 S dextransucrase activity
GKHACAHP_00752 0.0 S dextransucrase activity
GKHACAHP_00753 1.1e-89 S dextransucrase activity
GKHACAHP_00754 0.0 S dextransucrase activity
GKHACAHP_00755 8.4e-97 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GKHACAHP_00756 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GKHACAHP_00757 0.0 M Putative cell wall binding repeat
GKHACAHP_00758 0.0 M Putative cell wall binding repeat
GKHACAHP_00759 0.0 M Putative cell wall binding repeat
GKHACAHP_00760 1.5e-173 S dextransucrase activity
GKHACAHP_00761 3.9e-304 S dextransucrase activity
GKHACAHP_00762 0.0 M Putative cell wall binding repeat
GKHACAHP_00764 2.6e-136 L Transposase and inactivated derivatives
GKHACAHP_00765 9.6e-76 L Transposase
GKHACAHP_00766 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
GKHACAHP_00768 7.4e-283 S Protein of unknown function (DUF3114)
GKHACAHP_00769 1.1e-98 2.3.1.128 K Acetyltransferase GNAT Family
GKHACAHP_00770 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GKHACAHP_00771 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
GKHACAHP_00772 6.4e-178 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
GKHACAHP_00773 1.2e-187 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GKHACAHP_00774 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GKHACAHP_00775 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
GKHACAHP_00776 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GKHACAHP_00777 1.9e-186 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GKHACAHP_00778 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GKHACAHP_00779 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GKHACAHP_00782 1.8e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GKHACAHP_00783 1.3e-169 vraS 2.7.13.3 T Histidine kinase
GKHACAHP_00784 1.6e-115 yvqF S Membrane
GKHACAHP_00785 4.1e-104 kcsA P Ion transport protein
GKHACAHP_00786 1.4e-291 prkC 2.7.11.1 KLT serine threonine protein kinase
GKHACAHP_00787 1.3e-134 stp 3.1.3.16 T phosphatase
GKHACAHP_00788 2.7e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GKHACAHP_00789 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GKHACAHP_00790 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GKHACAHP_00791 1.4e-45 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
GKHACAHP_00792 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GKHACAHP_00793 2.4e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GKHACAHP_00794 2.7e-146 XK27_02985 S overlaps another CDS with the same product name
GKHACAHP_00795 4.5e-146 supH S overlaps another CDS with the same product name
GKHACAHP_00796 5.6e-62 yvoA_1 K Transcriptional
GKHACAHP_00797 1.8e-119 skfE V abc transporter atp-binding protein
GKHACAHP_00798 1.1e-128 V Psort location CytoplasmicMembrane, score
GKHACAHP_00799 1.6e-171 oppF P Belongs to the ABC transporter superfamily
GKHACAHP_00800 4.6e-202 oppD P Belongs to the ABC transporter superfamily
GKHACAHP_00801 3.8e-165 amiD P ABC transporter (Permease
GKHACAHP_00802 1.1e-275 amiC P ABC transporter (Permease
GKHACAHP_00803 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
GKHACAHP_00804 0.0 amiA E ABC transporter, substrate-binding protein, family 5
GKHACAHP_00805 1e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
GKHACAHP_00806 1e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
GKHACAHP_00807 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GKHACAHP_00808 3e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
GKHACAHP_00809 5.4e-101 yjbK S Adenylate cyclase
GKHACAHP_00810 1.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GKHACAHP_00811 6.6e-204 iscS 2.8.1.7 E Cysteine desulfurase
GKHACAHP_00812 1.4e-59 XK27_04120 S Putative amino acid metabolism
GKHACAHP_00813 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GKHACAHP_00814 1.8e-127 puuD T peptidase C26
GKHACAHP_00815 6.9e-119 radC E Belongs to the UPF0758 family
GKHACAHP_00816 0.0 rgpF M Rhamnan synthesis protein F
GKHACAHP_00817 1.6e-183 rgpEc GT2 M Glycosyl transferase family 2
GKHACAHP_00818 8.1e-224 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GKHACAHP_00819 2.6e-141 rgpC GM Transport permease protein
GKHACAHP_00820 1.1e-170 rgpB GT2 M Glycosyltransferase, group 2 family protein
GKHACAHP_00821 6.6e-215 rgpA GT4 M Domain of unknown function (DUF1972)
GKHACAHP_00822 2.1e-139 S Predicted membrane protein (DUF2142)
GKHACAHP_00823 1.7e-179 tagF 2.7.8.12 M Glycosyl transferase, family 2
GKHACAHP_00824 1.6e-214 amrA S polysaccharide biosynthetic process
GKHACAHP_00825 4.5e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
GKHACAHP_00826 6.5e-125 ycbB S Glycosyl transferase family 2
GKHACAHP_00827 8.4e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GKHACAHP_00828 5.7e-215 S Predicted membrane protein (DUF2142)
GKHACAHP_00829 2e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
GKHACAHP_00830 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
GKHACAHP_00831 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GKHACAHP_00832 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GKHACAHP_00833 6.4e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GKHACAHP_00834 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GKHACAHP_00835 5.7e-133 gltS ET Belongs to the bacterial solute-binding protein 3 family
GKHACAHP_00836 8.9e-209 arcT 2.6.1.1 E Aminotransferase
GKHACAHP_00837 5e-137 ET Belongs to the bacterial solute-binding protein 3 family
GKHACAHP_00838 3.2e-139 ET ABC transporter
GKHACAHP_00839 1.8e-83 mutT 3.6.1.55 F Nudix family
GKHACAHP_00840 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GKHACAHP_00842 1.6e-163 S CAAX amino terminal protease family protein
GKHACAHP_00843 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
GKHACAHP_00844 1e-136 glnQ 3.6.3.21 E abc transporter atp-binding protein
GKHACAHP_00845 1.7e-17 XK27_00735
GKHACAHP_00846 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GKHACAHP_00848 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GKHACAHP_00849 4.4e-10 O ADP-ribosylglycohydrolase
GKHACAHP_00850 6.7e-63 paaI Q protein possibly involved in aromatic compounds catabolism
GKHACAHP_00851 1e-60 ycaO O OsmC-like protein
GKHACAHP_00853 4.2e-153 EG Permeases of the drug metabolite transporter (DMT) superfamily
GKHACAHP_00854 5.9e-07 N PFAM Uncharacterised protein family UPF0150
GKHACAHP_00855 9.1e-113 serB 3.1.3.3 E phosphoserine phosphatase
GKHACAHP_00856 8.4e-299 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GKHACAHP_00857 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKHACAHP_00858 4.1e-93 3.1.3.18 S IA, variant 1
GKHACAHP_00859 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GKHACAHP_00860 3.5e-56 lrgA S Effector of murein hydrolase LrgA
GKHACAHP_00862 2.1e-67 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
GKHACAHP_00863 3.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GKHACAHP_00864 3e-104 wecD M Acetyltransferase (GNAT) domain
GKHACAHP_00865 3e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GKHACAHP_00866 9.8e-158 GK ROK family
GKHACAHP_00867 1.8e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
GKHACAHP_00868 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
GKHACAHP_00869 1.7e-204 potD P spermidine putrescine ABC transporter
GKHACAHP_00870 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
GKHACAHP_00871 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
GKHACAHP_00872 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
GKHACAHP_00873 6.2e-168 murB 1.3.1.98 M cell wall formation
GKHACAHP_00874 3.7e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GKHACAHP_00875 1.7e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GKHACAHP_00876 2.4e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
GKHACAHP_00877 4.5e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GKHACAHP_00878 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
GKHACAHP_00879 0.0 ydaO E amino acid
GKHACAHP_00880 2e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GKHACAHP_00881 1.5e-36 ylqC L Belongs to the UPF0109 family
GKHACAHP_00882 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GKHACAHP_00884 4.8e-201 2.7.13.3 T protein histidine kinase activity
GKHACAHP_00885 2.6e-124 agrA KT phosphorelay signal transduction system
GKHACAHP_00886 1.1e-165 O protein import
GKHACAHP_00887 1.5e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
GKHACAHP_00888 3.7e-17 yjdB S Domain of unknown function (DUF4767)
GKHACAHP_00889 2.7e-199 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GKHACAHP_00891 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
GKHACAHP_00892 3.4e-72 S QueT transporter
GKHACAHP_00894 2.3e-171 yfjR K regulation of single-species biofilm formation
GKHACAHP_00896 8.4e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GKHACAHP_00897 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GKHACAHP_00898 1.7e-85 ccl S cog cog4708
GKHACAHP_00899 4.8e-163 rbn E Belongs to the UPF0761 family
GKHACAHP_00900 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
GKHACAHP_00901 3e-232 ytoI K transcriptional regulator containing CBS domains
GKHACAHP_00902 7e-98 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
GKHACAHP_00903 2.3e-229 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKHACAHP_00904 0.0 comEC S Competence protein ComEC
GKHACAHP_00905 1.5e-92 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
GKHACAHP_00906 2.9e-142 plsC 2.3.1.51 I Acyltransferase
GKHACAHP_00907 8.1e-147 nodB3 G Polysaccharide deacetylase
GKHACAHP_00908 3.5e-140 yabB 2.1.1.223 L Methyltransferase
GKHACAHP_00909 6.6e-41 yazA L endonuclease containing a URI domain
GKHACAHP_00910 1.4e-244 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GKHACAHP_00911 1.6e-152 corA P CorA-like protein
GKHACAHP_00912 3.3e-62 yjqA S Bacterial PH domain
GKHACAHP_00913 1.7e-99 thiT S Thiamine transporter
GKHACAHP_00914 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GKHACAHP_00915 1.5e-115 ywaF S Integral membrane protein (intg_mem_TP0381)
GKHACAHP_00916 4.1e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GKHACAHP_00920 3.3e-155 cjaA ET ABC transporter substrate-binding protein
GKHACAHP_00921 1.5e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
GKHACAHP_00922 4.6e-107 P ABC transporter (Permease
GKHACAHP_00923 8.6e-114 papP P ABC transporter (Permease
GKHACAHP_00924 1e-190 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GKHACAHP_00925 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
GKHACAHP_00926 0.0 copA 3.6.3.54 P P-type ATPase
GKHACAHP_00927 6.1e-73 copY K negative regulation of transcription, DNA-templated
GKHACAHP_00928 2.1e-155 EGP Major facilitator Superfamily
GKHACAHP_00930 1.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GKHACAHP_00931 1.4e-228 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GKHACAHP_00932 5.1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
GKHACAHP_00933 1.6e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
GKHACAHP_00934 3e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GKHACAHP_00935 8e-105 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
GKHACAHP_00936 2.8e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GKHACAHP_00937 1.3e-39 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase type II
GKHACAHP_00938 2e-58
GKHACAHP_00939 0.0 ctpE P E1-E2 ATPase
GKHACAHP_00940 3.8e-45
GKHACAHP_00941 3.5e-51
GKHACAHP_00942 3.3e-91 V Restriction endonuclease
GKHACAHP_00944 1.4e-42
GKHACAHP_00945 2.6e-181 D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GKHACAHP_00946 1.5e-53
GKHACAHP_00947 3.6e-84 S Plasmid replication protein
GKHACAHP_00948 5.6e-20 S Domain of unknown function (DUF3173)
GKHACAHP_00949 1.5e-190 L Pfam:Integrase_AP2
GKHACAHP_00950 3.9e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GKHACAHP_00952 1.9e-124 V abc transporter atp-binding protein
GKHACAHP_00953 0.0 V ABC transporter (Permease
GKHACAHP_00954 9.9e-124 K transcriptional regulator, MerR family
GKHACAHP_00955 1.2e-103 dnaQ 2.7.7.7 L DNA polymerase III
GKHACAHP_00956 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
GKHACAHP_00957 9.6e-64 XK27_02560 S cog cog2151
GKHACAHP_00958 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GKHACAHP_00959 1.4e-220 ytfP S Flavoprotein
GKHACAHP_00961 2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GKHACAHP_00962 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
GKHACAHP_00963 1e-174 ecsB U Bacterial ABC transporter protein EcsB
GKHACAHP_00964 3.7e-131 ecsA V abc transporter atp-binding protein
GKHACAHP_00965 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GKHACAHP_00966 4.6e-07
GKHACAHP_00967 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GKHACAHP_00968 3.1e-69 argR K Regulates arginine biosynthesis genes
GKHACAHP_00969 2.2e-55 ymcA 3.6.3.21 S Belongs to the UPF0342 family
GKHACAHP_00970 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GKHACAHP_00971 1.2e-79 S Protein of unknown function (DUF3021)
GKHACAHP_00972 8.4e-70 K LytTr DNA-binding domain
GKHACAHP_00974 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GKHACAHP_00976 3e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GKHACAHP_00977 2.3e-104 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
GKHACAHP_00978 4e-229 cinA 3.5.1.42 S Belongs to the CinA family
GKHACAHP_00979 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GKHACAHP_00980 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
GKHACAHP_00981 1.5e-12
GKHACAHP_00983 1.7e-221 L transposase IS116 IS110 IS902 family
GKHACAHP_00984 6.5e-111 tcyB_2 P ABC transporter (permease)
GKHACAHP_00985 1.9e-116 gltJ P ABC transporter (Permease
GKHACAHP_00986 5.2e-119 glnQ 3.6.3.21 E abc transporter atp-binding protein
GKHACAHP_00989 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GKHACAHP_00990 2.2e-82 comFC S Competence protein
GKHACAHP_00991 2.1e-249 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GKHACAHP_00992 2.9e-108 yvyE 3.4.13.9 S YigZ family
GKHACAHP_00993 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GKHACAHP_00994 1.6e-112 acuB S CBS domain
GKHACAHP_00995 5.6e-124 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
GKHACAHP_00996 4e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
GKHACAHP_00997 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
GKHACAHP_00998 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
GKHACAHP_00999 2.6e-211 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
GKHACAHP_01000 1.9e-46 ylbG S UPF0298 protein
GKHACAHP_01001 6.4e-73 ylbF S Belongs to the UPF0342 family
GKHACAHP_01002 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GKHACAHP_01003 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GKHACAHP_01004 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
GKHACAHP_01005 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
GKHACAHP_01006 2.5e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GKHACAHP_01007 3.3e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
GKHACAHP_01008 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
GKHACAHP_01009 2.2e-288 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
GKHACAHP_01010 5.8e-269 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GKHACAHP_01011 1e-99 yvdD 3.2.2.10 S Belongs to the LOG family
GKHACAHP_01012 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GKHACAHP_01013 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GKHACAHP_01014 1.4e-41 ylxQ J ribosomal protein
GKHACAHP_01015 2.3e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
GKHACAHP_01016 4e-199 nusA K Participates in both transcription termination and antitermination
GKHACAHP_01017 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
GKHACAHP_01018 5.7e-188 brpA K Transcriptional
GKHACAHP_01019 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
GKHACAHP_01020 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
GKHACAHP_01021 1.6e-247 pbuO S permease
GKHACAHP_01022 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
GKHACAHP_01023 7.8e-137 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
GKHACAHP_01024 1.2e-167 manL 2.7.1.191 G pts system
GKHACAHP_01025 4.1e-131 manY G pts system
GKHACAHP_01026 9.1e-159 manN G PTS system mannose fructose sorbose family IID component
GKHACAHP_01027 1e-66 manO S Protein conserved in bacteria
GKHACAHP_01028 4.9e-174 manL 2.7.1.191 G pts system
GKHACAHP_01029 9.4e-115 manM G pts system
GKHACAHP_01030 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
GKHACAHP_01031 1.9e-62 manO S protein conserved in bacteria
GKHACAHP_01032 1.4e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GKHACAHP_01033 1e-113
GKHACAHP_01034 5.7e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GKHACAHP_01035 4.4e-166 dnaI L Primosomal protein DnaI
GKHACAHP_01036 4.4e-214 dnaB L Replication initiation and membrane attachment
GKHACAHP_01037 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GKHACAHP_01038 6.6e-279 T PhoQ Sensor
GKHACAHP_01039 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKHACAHP_01040 6.9e-90 yceD K metal-binding, possibly nucleic acid-binding protein
GKHACAHP_01041 1.6e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
GKHACAHP_01042 2.9e-233 P COG0168 Trk-type K transport systems, membrane components
GKHACAHP_01043 3.7e-117 ktrA P COG0569 K transport systems, NAD-binding component
GKHACAHP_01044 1.9e-147 cbiQ P cobalt transport
GKHACAHP_01045 9.6e-308 ykoD P abc transporter atp-binding protein
GKHACAHP_01046 8e-94 S UPF0397 protein
GKHACAHP_01047 6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
GKHACAHP_01048 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GKHACAHP_01049 1.2e-99 metI P ABC transporter (Permease
GKHACAHP_01050 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GKHACAHP_01051 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
GKHACAHP_01052 1.6e-163 metQ M Belongs to the NlpA lipoprotein family
GKHACAHP_01053 6.3e-138 ET ABC transporter substrate-binding protein
GKHACAHP_01054 7.7e-129 cbiO P ABC transporter
GKHACAHP_01055 1.1e-136 P cobalt transport protein
GKHACAHP_01056 3.9e-176 cbiM P biosynthesis protein CbiM
GKHACAHP_01057 1.6e-157 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GKHACAHP_01058 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
GKHACAHP_01059 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
GKHACAHP_01060 6.6e-78 ureE O enzyme active site formation
GKHACAHP_01061 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GKHACAHP_01062 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
GKHACAHP_01063 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
GKHACAHP_01064 6.8e-95 ureI S AmiS/UreI family transporter
GKHACAHP_01065 2e-250 S Domain of unknown function (DUF4173)
GKHACAHP_01066 2.9e-54 yhaI L Membrane
GKHACAHP_01067 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
GKHACAHP_01068 2.3e-154 K sequence-specific DNA binding
GKHACAHP_01069 1.4e-100 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
GKHACAHP_01070 6e-89 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GKHACAHP_01071 1.1e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GKHACAHP_01072 3.8e-246 trkA P Potassium transporter peripheral membrane component
GKHACAHP_01073 4.2e-259 trkH P Cation transport protein
GKHACAHP_01074 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
GKHACAHP_01075 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GKHACAHP_01076 1.5e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GKHACAHP_01077 1.4e-122 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GKHACAHP_01078 6.8e-131 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
GKHACAHP_01079 2.7e-85 ykuL S CBS domain
GKHACAHP_01080 7.4e-97 XK27_09740 S Phosphoesterase
GKHACAHP_01081 1.7e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GKHACAHP_01082 1.5e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GKHACAHP_01083 1.6e-36 yneF S UPF0154 protein
GKHACAHP_01084 1.8e-90 K transcriptional regulator
GKHACAHP_01085 5.3e-242 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GKHACAHP_01086 4.2e-12 ycdA S Domain of unknown function (DUF4352)
GKHACAHP_01087 4.8e-96 ybhL S Belongs to the BI1 family
GKHACAHP_01088 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
GKHACAHP_01089 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GKHACAHP_01090 1.3e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GKHACAHP_01091 7.7e-166 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GKHACAHP_01092 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GKHACAHP_01093 1.7e-303 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GKHACAHP_01094 3.2e-86 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
GKHACAHP_01095 1.2e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GKHACAHP_01096 9.6e-23
GKHACAHP_01097 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
GKHACAHP_01098 7.5e-275 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
GKHACAHP_01099 9.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GKHACAHP_01100 5.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GKHACAHP_01101 5.2e-95 ypsA S Belongs to the UPF0398 family
GKHACAHP_01102 4.8e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GKHACAHP_01103 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GKHACAHP_01104 1.3e-254 pepC 3.4.22.40 E aminopeptidase
GKHACAHP_01105 2e-74 yhaI S Protein of unknown function (DUF805)
GKHACAHP_01106 2.9e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GKHACAHP_01107 4.3e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GKHACAHP_01108 6e-217 macB_2 V FtsX-like permease family
GKHACAHP_01109 4.7e-120 yhcA V abc transporter atp-binding protein
GKHACAHP_01110 9.6e-124 mta K Transcriptional
GKHACAHP_01111 8.9e-32 S Protein of unknown function (DUF3021)
GKHACAHP_01112 7.6e-74 K COG3279 Response regulator of the LytR AlgR family
GKHACAHP_01113 3.4e-128 cylB V ABC-2 type transporter
GKHACAHP_01114 6e-152 cylA V abc transporter atp-binding protein
GKHACAHP_01115 2.5e-231 S COG1073 Hydrolases of the alpha beta superfamily
GKHACAHP_01116 5.8e-74 K helix_turn_helix multiple antibiotic resistance protein
GKHACAHP_01117 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GKHACAHP_01118 3.6e-132 glcR K transcriptional regulator (DeoR family)
GKHACAHP_01119 2.7e-146 cof S Sucrose-6F-phosphate phosphohydrolase
GKHACAHP_01120 2.9e-71 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
GKHACAHP_01121 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
GKHACAHP_01122 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
GKHACAHP_01123 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GKHACAHP_01124 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GKHACAHP_01125 1.5e-163 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GKHACAHP_01126 5.8e-55 S TM2 domain
GKHACAHP_01127 1.9e-44
GKHACAHP_01129 2.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GKHACAHP_01130 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GKHACAHP_01131 1.4e-142 cmpC S abc transporter atp-binding protein
GKHACAHP_01132 0.0 WQ51_06230 S ABC transporter
GKHACAHP_01133 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GKHACAHP_01134 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
GKHACAHP_01135 2.1e-143 cdsA 2.7.7.41 S Belongs to the CDS family
GKHACAHP_01136 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GKHACAHP_01137 4.4e-47 yajC U protein transport
GKHACAHP_01138 6.1e-126 yeeN K transcriptional regulatory protein
GKHACAHP_01139 3.6e-280 V ABC transporter
GKHACAHP_01140 1.4e-153 Z012_04635 K sequence-specific DNA binding
GKHACAHP_01141 8.2e-219 L the current gene model (or a revised gene model) may contain a frame shift
GKHACAHP_01142 1.3e-305 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKHACAHP_01143 1.1e-108 L Transposase IS116 IS110 IS902
GKHACAHP_01144 9.2e-59 L MULE transposase domain
GKHACAHP_01145 8.1e-16 tnp* L An automated process has identified a potential problem with this gene model
GKHACAHP_01146 4.2e-59 srlB 2.7.1.198 G sorbitol-specific, IIA component
GKHACAHP_01147 3.8e-179 srlE 2.7.1.198 G PTS sorbitol transporter subunit IIB
GKHACAHP_01148 1.1e-95 srlA G PTS system glucitol sorbitol-specific
GKHACAHP_01149 6.8e-84 gutM K phosphoenolpyruvate-dependent sugar phosphotransferase system
GKHACAHP_01150 0.0 srlM 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
GKHACAHP_01151 1.4e-142 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GKHACAHP_01152 4.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
GKHACAHP_01153 4.6e-154 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
GKHACAHP_01154 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GKHACAHP_01155 5.5e-159 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
GKHACAHP_01156 1.9e-128 adcB P ABC transporter (Permease
GKHACAHP_01157 7.1e-135 adcC P ABC transporter, ATP-binding protein
GKHACAHP_01158 1e-70 adcR K transcriptional
GKHACAHP_01159 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GKHACAHP_01160 7.3e-158 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GKHACAHP_01161 4.7e-26
GKHACAHP_01162 2.9e-273 sufB O assembly protein SufB
GKHACAHP_01163 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
GKHACAHP_01164 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GKHACAHP_01165 6.9e-234 sufD O assembly protein SufD
GKHACAHP_01166 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GKHACAHP_01167 1.5e-182 tagO 2.7.8.33, 2.7.8.35 M transferase
GKHACAHP_01168 2.2e-126 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
GKHACAHP_01169 4.8e-18 S Protein of unknown function (DUF3021)
GKHACAHP_01170 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GKHACAHP_01171 2.7e-272 glnP P ABC transporter
GKHACAHP_01172 5e-123 glnQ E abc transporter atp-binding protein
GKHACAHP_01173 1.4e-177 D nuclear chromosome segregation
GKHACAHP_01174 4.4e-82 V VanZ like family
GKHACAHP_01175 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GKHACAHP_01176 2.6e-182 yhjX P Major Facilitator
GKHACAHP_01177 3.1e-105 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
GKHACAHP_01178 2.5e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GKHACAHP_01179 2.5e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GKHACAHP_01180 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
GKHACAHP_01181 2.4e-72 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GKHACAHP_01182 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GKHACAHP_01183 3.1e-83 nrdI F Belongs to the NrdI family
GKHACAHP_01184 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
GKHACAHP_01185 1.4e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GKHACAHP_01186 1e-176 prmA J Ribosomal protein L11 methyltransferase
GKHACAHP_01187 1.9e-75 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
GKHACAHP_01188 1.1e-83 XK27_03960 S Protein of unknown function (DUF3013)
GKHACAHP_01189 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GKHACAHP_01190 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GKHACAHP_01191 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GKHACAHP_01192 5.8e-138 ykuT M mechanosensitive ion channel
GKHACAHP_01193 4.3e-86 sigH K DNA-templated transcription, initiation
GKHACAHP_01194 1.9e-88 L COG1943 Transposase and inactivated derivatives
GKHACAHP_01195 2.4e-84 L the current gene model (or a revised gene model) may contain a frame shift
GKHACAHP_01196 5.2e-150 cbiO2 P Zeta toxin
GKHACAHP_01197 3.5e-157 P abc transporter atp-binding protein
GKHACAHP_01198 1.3e-132 cbiQ P Cobalt transport protein
GKHACAHP_01199 2.2e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
GKHACAHP_01200 1.6e-143 S Phenazine biosynthesis protein
GKHACAHP_01201 1.7e-108 magIII L Base excision DNA repair protein, HhH-GPD family
GKHACAHP_01202 1.2e-259 proWX P ABC transporter
GKHACAHP_01203 1.1e-127 proV E abc transporter atp-binding protein
GKHACAHP_01204 6.3e-138 1.6.5.2 GM epimerase
GKHACAHP_01205 1.1e-67 mgrA K Transcriptional regulator, MarR family
GKHACAHP_01206 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
GKHACAHP_01207 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GKHACAHP_01210 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GKHACAHP_01212 2.4e-136 IQ Acetoin reductase
GKHACAHP_01213 9.1e-44 pspE P Rhodanese-like protein
GKHACAHP_01214 1.4e-71 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GKHACAHP_01215 2.9e-223 XK27_05470 E Methionine synthase
GKHACAHP_01216 4.8e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GKHACAHP_01217 2.4e-227 T PhoQ Sensor
GKHACAHP_01218 8.6e-119 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKHACAHP_01219 1.2e-141 S TraX protein
GKHACAHP_01221 4.1e-53 V ABC-2 family transporter protein
GKHACAHP_01222 2.3e-82 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
GKHACAHP_01223 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GKHACAHP_01224 1.2e-157 dprA LU DNA protecting protein DprA
GKHACAHP_01225 3.3e-169 GK ROK family
GKHACAHP_01226 3.2e-133 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKHACAHP_01227 3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GKHACAHP_01228 5.3e-127 K DNA-binding helix-turn-helix protein
GKHACAHP_01229 6e-91 niaR S small molecule binding protein (contains 3H domain)
GKHACAHP_01230 2.7e-86
GKHACAHP_01231 1e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GKHACAHP_01232 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GKHACAHP_01233 8.5e-125 gntR1 K transcriptional
GKHACAHP_01234 5.1e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GKHACAHP_01235 8.8e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GKHACAHP_01236 9.4e-189 adhP 1.1.1.1 C alcohol dehydrogenase
GKHACAHP_01237 1e-44
GKHACAHP_01238 2.2e-70 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKHACAHP_01239 2.1e-179 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKHACAHP_01240 1.3e-156 aatB ET ABC transporter substrate-binding protein
GKHACAHP_01241 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
GKHACAHP_01242 3.1e-105 artQ P ABC transporter (Permease
GKHACAHP_01243 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
GKHACAHP_01244 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GKHACAHP_01245 8.4e-165 cpsY K Transcriptional regulator
GKHACAHP_01246 2.7e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
GKHACAHP_01247 4e-168 yeiH S Membrane
GKHACAHP_01249 2.6e-09
GKHACAHP_01250 8.1e-285 adcA P Belongs to the bacterial solute-binding protein 9 family
GKHACAHP_01251 1.8e-145 XK27_10720 D peptidase activity
GKHACAHP_01252 9.6e-277 pepD E Dipeptidase
GKHACAHP_01253 5.7e-161 whiA K May be required for sporulation
GKHACAHP_01254 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GKHACAHP_01255 3.8e-162 rapZ S Displays ATPase and GTPase activities
GKHACAHP_01256 9.1e-136 yejC S cyclic nucleotide-binding protein
GKHACAHP_01257 5.2e-196 D nuclear chromosome segregation
GKHACAHP_01258 1.4e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
GKHACAHP_01259 2.7e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GKHACAHP_01260 2.4e-80 queD 4.1.2.50, 4.2.3.12 H synthase
GKHACAHP_01261 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GKHACAHP_01262 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
GKHACAHP_01263 5.3e-18
GKHACAHP_01264 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
GKHACAHP_01265 9.1e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GKHACAHP_01266 1.1e-81 ypmB S Protein conserved in bacteria
GKHACAHP_01267 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GKHACAHP_01268 4.7e-114 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
GKHACAHP_01269 3.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
GKHACAHP_01270 1.7e-180 yufP S Belongs to the binding-protein-dependent transport system permease family
GKHACAHP_01271 1.6e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
GKHACAHP_01272 3.2e-187 tcsA S membrane
GKHACAHP_01273 1.1e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GKHACAHP_01274 1e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GKHACAHP_01275 4.7e-230 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
GKHACAHP_01276 3.5e-103 rsmC 2.1.1.172 J Methyltransferase small domain protein
GKHACAHP_01277 1.6e-171 coaA 2.7.1.33 F Pantothenic acid kinase
GKHACAHP_01278 1e-29 rpsT J Binds directly to 16S ribosomal RNA
GKHACAHP_01279 1.7e-241 T PhoQ Sensor
GKHACAHP_01280 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GKHACAHP_01281 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
GKHACAHP_01282 9e-111 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
GKHACAHP_01283 1.4e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GKHACAHP_01284 7.8e-92 panT S ECF transporter, substrate-specific component
GKHACAHP_01285 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
GKHACAHP_01286 5.3e-164 metF 1.5.1.20 E reductase
GKHACAHP_01287 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GKHACAHP_01289 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
GKHACAHP_01290 0.0 3.6.3.8 P cation transport ATPase
GKHACAHP_01291 5.3e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GKHACAHP_01292 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKHACAHP_01293 5.6e-236 dltB M Membrane protein involved in D-alanine export
GKHACAHP_01294 1.5e-294 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GKHACAHP_01295 0.0 XK27_10035 V abc transporter atp-binding protein
GKHACAHP_01296 8.5e-291 yfiB1 V abc transporter atp-binding protein
GKHACAHP_01297 1.4e-99 pvaA M lytic transglycosylase activity
GKHACAHP_01298 5.5e-178 ndpA S 37-kD nucleoid-associated bacterial protein
GKHACAHP_01299 2.7e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GKHACAHP_01300 4.5e-106 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GKHACAHP_01301 8.3e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GKHACAHP_01302 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GKHACAHP_01303 5.1e-110 tdk 2.7.1.21 F thymidine kinase
GKHACAHP_01304 7.6e-183 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GKHACAHP_01305 4.9e-153 gst O Glutathione S-transferase
GKHACAHP_01306 1.7e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
GKHACAHP_01307 2e-169 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
GKHACAHP_01308 4.4e-45 rpmE2 J 50S ribosomal protein L31
GKHACAHP_01309 4.3e-203 mntH P Mn2 and Fe2 transporters of the NRAMP family
GKHACAHP_01310 2.7e-16 mntH P Mn2 and Fe2 transporters of the NRAMP family
GKHACAHP_01311 6.4e-163 ypuA S secreted protein
GKHACAHP_01312 3.7e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
GKHACAHP_01313 4.6e-132 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
GKHACAHP_01314 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GKHACAHP_01315 9.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GKHACAHP_01316 1.2e-255 noxE P NADH oxidase
GKHACAHP_01317 1.1e-294 yfmM S abc transporter atp-binding protein
GKHACAHP_01318 8e-83 XK27_01265 S ECF-type riboflavin transporter, S component
GKHACAHP_01319 1.7e-154 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
GKHACAHP_01320 8.2e-85 S ECF-type riboflavin transporter, S component
GKHACAHP_01322 3.3e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GKHACAHP_01323 2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
GKHACAHP_01325 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKHACAHP_01326 9.2e-92 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKHACAHP_01327 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GKHACAHP_01328 1.3e-22 WQ51_00220 K Helix-turn-helix domain
GKHACAHP_01329 3.7e-91 S Protein of unknown function (DUF3278)
GKHACAHP_01330 0.0 smc D Required for chromosome condensation and partitioning
GKHACAHP_01331 2.7e-123 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GKHACAHP_01332 1.9e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GKHACAHP_01333 2.8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GKHACAHP_01334 8.8e-124 alkD L DNA alkylation repair enzyme
GKHACAHP_01335 3.3e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKHACAHP_01336 5.2e-87 pat 2.3.1.183 M acetyltransferase
GKHACAHP_01337 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GKHACAHP_01338 2.6e-152 L PFAM Integrase catalytic region
GKHACAHP_01339 7.4e-278 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GKHACAHP_01340 3.4e-36 P (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GKHACAHP_01341 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GKHACAHP_01342 3.2e-98 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
GKHACAHP_01343 1.5e-18 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
GKHACAHP_01344 3e-119 sdaAB 4.3.1.17 E L-serine dehydratase
GKHACAHP_01345 5.8e-147 sdaAA 4.3.1.17 E L-serine dehydratase
GKHACAHP_01346 2.1e-123 tktC 2.2.1.1 G Transketolase, pyrimidine binding domain
GKHACAHP_01347 1.2e-123 tktN 2.2.1.1 G 1-deoxy-D-xylulose-5-phosphate synthase
GKHACAHP_01348 2e-215 ulaA 2.7.1.194 S PTS system sugar-specific permease component
GKHACAHP_01349 3.7e-42 ulaB 2.7.1.194 G COG3414 Phosphotransferase system galactitol-specific IIB component
GKHACAHP_01350 9.8e-222 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
GKHACAHP_01351 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
GKHACAHP_01352 5.7e-132 L Integrase
GKHACAHP_01353 3.5e-202 S Protein of unknown function DUF262
GKHACAHP_01354 1.2e-151 S Protein of unknown function DUF262
GKHACAHP_01355 1.7e-63 mutT 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GKHACAHP_01356 3.4e-78 3.4.21.89 S RDD family
GKHACAHP_01357 8.3e-30 K sequence-specific DNA binding
GKHACAHP_01358 6.6e-50 ywrO S general stress protein
GKHACAHP_01363 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
GKHACAHP_01364 1.5e-60 L thioesterase
GKHACAHP_01365 5.7e-39 L COG1943 Transposase and inactivated derivatives
GKHACAHP_01366 6e-143 S Macro domain protein
GKHACAHP_01367 2.4e-50 trxA O Belongs to the thioredoxin family
GKHACAHP_01368 2.7e-73 yccU S CoA-binding protein
GKHACAHP_01369 6.1e-143 tatD L Hydrolase, tatd
GKHACAHP_01370 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GKHACAHP_01371 5.8e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GKHACAHP_01373 1.2e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GKHACAHP_01374 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GKHACAHP_01375 2.3e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
GKHACAHP_01376 2.5e-170 rmuC S RmuC domain protein
GKHACAHP_01377 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
GKHACAHP_01378 4e-142 purR 2.4.2.7 F operon repressor
GKHACAHP_01379 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GKHACAHP_01380 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GKHACAHP_01381 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GKHACAHP_01382 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
GKHACAHP_01383 5.6e-124
GKHACAHP_01384 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GKHACAHP_01385 8.7e-87 S Fusaric acid resistance protein-like
GKHACAHP_01386 2.5e-62 glnR K Transcriptional regulator
GKHACAHP_01387 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
GKHACAHP_01388 8e-114 pscB M CHAP domain protein
GKHACAHP_01389 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKHACAHP_01390 4.3e-33 ykzG S Belongs to the UPF0356 family
GKHACAHP_01391 7.9e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
GKHACAHP_01392 1.5e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GKHACAHP_01393 1.6e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GKHACAHP_01394 1.4e-111 azlC E AzlC protein
GKHACAHP_01395 2.2e-46 azlD S branched-chain amino acid
GKHACAHP_01396 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GKHACAHP_01397 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
GKHACAHP_01398 2.1e-152 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GKHACAHP_01399 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GKHACAHP_01400 6.1e-94 cvpA S toxin biosynthetic process
GKHACAHP_01401 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GKHACAHP_01402 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GKHACAHP_01404 4.9e-34
GKHACAHP_01406 3.3e-222 mutY L A G-specific adenine glycosylase
GKHACAHP_01407 9.5e-42 XK27_05745
GKHACAHP_01408 2.3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
GKHACAHP_01409 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKHACAHP_01410 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GKHACAHP_01412 3.8e-122 XK27_01040 S Protein of unknown function (DUF1129)
GKHACAHP_01413 6.5e-168 corA P COG0598 Mg2 and Co2 transporters
GKHACAHP_01414 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GKHACAHP_01418 1.6e-32 blpT
GKHACAHP_01419 1.1e-144 V 'abc transporter, ATP-binding protein
GKHACAHP_01421 4.1e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
GKHACAHP_01422 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
GKHACAHP_01423 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GKHACAHP_01424 1.7e-61 yqhY S protein conserved in bacteria
GKHACAHP_01425 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GKHACAHP_01426 1.2e-177 scrR K Transcriptional regulator
GKHACAHP_01427 1.2e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
GKHACAHP_01428 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GKHACAHP_01429 7.7e-171 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
GKHACAHP_01430 4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
GKHACAHP_01432 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GKHACAHP_01433 1.1e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GKHACAHP_01434 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GKHACAHP_01435 4.7e-61 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GKHACAHP_01436 2.1e-202 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GKHACAHP_01437 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GKHACAHP_01441 2.9e-31 yozG K Transcriptional regulator
GKHACAHP_01443 3.7e-168 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GKHACAHP_01444 8.9e-259 XK27_03190 5.2.1.8 S hydrolases of the HAD superfamily
GKHACAHP_01445 2.4e-95 yebC M Membrane
GKHACAHP_01446 1.2e-310 KT response to antibiotic
GKHACAHP_01447 1.3e-73 XK27_02470 K LytTr DNA-binding domain
GKHACAHP_01448 5.3e-119 liaI S membrane
GKHACAHP_01449 8.7e-78 mccF V LD-carboxypeptidase
GKHACAHP_01450 5.3e-43 S Sugar efflux transporter for intercellular exchange
GKHACAHP_01451 2.6e-194 mccF V LD-carboxypeptidase
GKHACAHP_01452 1.7e-298 O MreB/Mbl protein
GKHACAHP_01454 5.8e-146 V Psort location CytoplasmicMembrane, score
GKHACAHP_01457 1.5e-13
GKHACAHP_01458 8.5e-235 dcuS 2.7.13.3 T protein histidine kinase activity
GKHACAHP_01459 6e-239 2.7.13.3 T protein histidine kinase activity
GKHACAHP_01460 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GKHACAHP_01461 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GKHACAHP_01462 3.6e-126 S Protein of unknown function (DUF554)
GKHACAHP_01463 1.5e-132 ecsA_2 V abc transporter atp-binding protein
GKHACAHP_01464 1.7e-266 XK27_00765
GKHACAHP_01465 1.7e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GKHACAHP_01466 2.7e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GKHACAHP_01467 1e-58 yhaI J Membrane
GKHACAHP_01468 3.8e-61 yhaI J Protein of unknown function (DUF805)
GKHACAHP_01469 1.3e-48 yhaI J Protein of unknown function (DUF805)
GKHACAHP_01471 4.2e-96
GKHACAHP_01472 1.5e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GKHACAHP_01473 2.4e-45 ftsL D cell division protein FtsL
GKHACAHP_01474 0.0 ftsI 3.4.16.4 M penicillin-binding protein
GKHACAHP_01475 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GKHACAHP_01476 6.7e-211 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GKHACAHP_01478 1.2e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GKHACAHP_01479 6.2e-62 yutD J protein conserved in bacteria
GKHACAHP_01480 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GKHACAHP_01481 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
GKHACAHP_01484 0.0 mdlA V abc transporter atp-binding protein
GKHACAHP_01485 0.0 mdlB V abc transporter atp-binding protein
GKHACAHP_01494 3.1e-44 spiA K sequence-specific DNA binding
GKHACAHP_01495 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
GKHACAHP_01496 9.5e-150 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
GKHACAHP_01497 2.1e-95 V CAAX protease self-immunity
GKHACAHP_01498 3.1e-136 cppA E CppA N-terminal
GKHACAHP_01499 1.3e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
GKHACAHP_01501 5.4e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GKHACAHP_01502 3.3e-141 cah 4.2.1.1 P carbonic anhydrase
GKHACAHP_01503 0.0 pflB 2.3.1.54 C formate acetyltransferase'
GKHACAHP_01504 2.8e-202 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GKHACAHP_01505 3.6e-35
GKHACAHP_01506 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
GKHACAHP_01507 8e-163 yxeN P ABC transporter (Permease
GKHACAHP_01508 1.6e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
GKHACAHP_01509 5e-10 S Protein of unknown function (DUF4059)
GKHACAHP_01510 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GKHACAHP_01511 1.1e-104 rsmD 2.1.1.171 L Methyltransferase
GKHACAHP_01512 1.1e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GKHACAHP_01513 7.1e-187 ylbL T Belongs to the peptidase S16 family
GKHACAHP_01514 1.3e-181 yhcC S radical SAM protein
GKHACAHP_01515 3.2e-95 ytqB J (SAM)-dependent
GKHACAHP_01517 0.0 yjcE P NhaP-type Na H and K H antiporters
GKHACAHP_01518 1.8e-24
GKHACAHP_01520 1.2e-140 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
GKHACAHP_01521 3.2e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
GKHACAHP_01522 3.3e-10 MU outer membrane autotransporter barrel domain protein
GKHACAHP_01523 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKHACAHP_01525 1.2e-74 XK27_03180 T universal stress protein
GKHACAHP_01526 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
GKHACAHP_01527 5.3e-139 fnt P Formate nitrite transporter
GKHACAHP_01528 7.9e-97 XK27_08585 S Psort location CytoplasmicMembrane, score
GKHACAHP_01529 9.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GKHACAHP_01530 2.5e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GKHACAHP_01531 1.3e-117 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
GKHACAHP_01532 2.9e-93 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GKHACAHP_01533 1.9e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GKHACAHP_01534 2e-57 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GKHACAHP_01535 4.4e-135 S HAD hydrolase, family IA, variant
GKHACAHP_01536 7.8e-157 rrmA 2.1.1.187 Q methyltransferase
GKHACAHP_01540 6.6e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GKHACAHP_01541 4.3e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GKHACAHP_01542 1.2e-112 S CAAX protease self-immunity
GKHACAHP_01543 5.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GKHACAHP_01544 2.6e-09 S NTF2 fold immunity protein
GKHACAHP_01545 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GKHACAHP_01546 1.7e-07 S Domain of unknown function (DUF4651)
GKHACAHP_01547 1.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
GKHACAHP_01548 5.7e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GKHACAHP_01549 3.7e-101 S CAAX amino terminal protease family protein
GKHACAHP_01551 2e-107 V CAAX protease self-immunity
GKHACAHP_01552 8.8e-27 lanR K sequence-specific DNA binding
GKHACAHP_01553 4.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GKHACAHP_01554 2.2e-176 ytxK 2.1.1.72 L DNA methylase
GKHACAHP_01555 1.5e-12 comGF U Putative Competence protein ComGF
GKHACAHP_01556 9.9e-71 comGF U Competence protein ComGF
GKHACAHP_01557 5.3e-15 NU Type II secretory pathway pseudopilin
GKHACAHP_01558 1.4e-69 cglD NU Competence protein
GKHACAHP_01559 2.2e-43 comGC U Required for transformation and DNA binding
GKHACAHP_01560 1e-154 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GKHACAHP_01561 1.6e-174 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GKHACAHP_01562 1e-68 S cog cog4699
GKHACAHP_01563 1.1e-215 L the current gene model (or a revised gene model) may contain a frame shift
GKHACAHP_01564 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKHACAHP_01565 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKHACAHP_01566 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GKHACAHP_01567 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GKHACAHP_01568 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GKHACAHP_01569 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
GKHACAHP_01570 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
GKHACAHP_01571 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GKHACAHP_01572 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
GKHACAHP_01573 1.4e-57 asp S cog cog1302
GKHACAHP_01574 1.2e-225 norN V Mate efflux family protein
GKHACAHP_01575 1.3e-276 thrC 4.2.3.1 E Threonine synthase
GKHACAHP_01578 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
GKHACAHP_01579 0.0 pepO 3.4.24.71 O Peptidase family M13
GKHACAHP_01580 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
GKHACAHP_01581 4.7e-290 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GKHACAHP_01582 3.9e-125 treR K trehalose operon
GKHACAHP_01583 1.9e-95 ywlG S Belongs to the UPF0340 family
GKHACAHP_01586 8.2e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
GKHACAHP_01588 6e-241 6.3.2.2 H gamma-glutamylcysteine synthetase
GKHACAHP_01589 4.4e-62 rplQ J ribosomal protein l17
GKHACAHP_01590 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GKHACAHP_01591 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GKHACAHP_01592 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GKHACAHP_01593 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GKHACAHP_01594 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GKHACAHP_01595 6.2e-114 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GKHACAHP_01596 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GKHACAHP_01597 5.7e-58 rplO J binds to the 23S rRNA
GKHACAHP_01598 1.9e-23 rpmD J ribosomal protein l30
GKHACAHP_01599 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GKHACAHP_01600 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GKHACAHP_01601 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GKHACAHP_01602 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GKHACAHP_01603 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GKHACAHP_01604 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GKHACAHP_01605 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GKHACAHP_01606 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GKHACAHP_01607 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GKHACAHP_01608 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
GKHACAHP_01609 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GKHACAHP_01610 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GKHACAHP_01611 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GKHACAHP_01612 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GKHACAHP_01613 1.5e-152 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GKHACAHP_01614 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GKHACAHP_01615 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
GKHACAHP_01616 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GKHACAHP_01617 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
GKHACAHP_01618 3.3e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GKHACAHP_01619 0.0 XK27_09800 I Acyltransferase
GKHACAHP_01620 4.8e-35 XK27_09805 S MORN repeat protein
GKHACAHP_01621 3.4e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GKHACAHP_01622 2.7e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GKHACAHP_01623 1.9e-89 adk 2.7.4.3 F topology modulation protein
GKHACAHP_01624 5.6e-81 S Short repeat of unknown function (DUF308)
GKHACAHP_01625 7.7e-91 K TRANSCRIPTIONal
GKHACAHP_01626 2.8e-144 L Replication initiation factor
GKHACAHP_01627 1.9e-18 S Domain of unknown function (DUF3173)
GKHACAHP_01628 2.9e-215 int L Belongs to the 'phage' integrase family
GKHACAHP_01630 1.8e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
GKHACAHP_01631 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GKHACAHP_01632 6.3e-44 yrzL S Belongs to the UPF0297 family
GKHACAHP_01633 2.3e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GKHACAHP_01634 3.2e-44 yrzB S Belongs to the UPF0473 family
GKHACAHP_01635 4.4e-297 ccs S the current gene model (or a revised gene model) may contain a frame shift
GKHACAHP_01636 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
GKHACAHP_01637 7.5e-14
GKHACAHP_01638 1.9e-89 XK27_10930 K acetyltransferase
GKHACAHP_01639 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GKHACAHP_01640 3.6e-123 yaaA S Belongs to the UPF0246 family
GKHACAHP_01641 3.2e-167 XK27_01785 S cog cog1284
GKHACAHP_01642 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
GKHACAHP_01644 1.9e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
GKHACAHP_01645 4.1e-75 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GKHACAHP_01646 9.2e-102 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
GKHACAHP_01647 1.2e-218 metE 2.1.1.14 E Methionine synthase
GKHACAHP_01648 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GKHACAHP_01649 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GKHACAHP_01650 4.3e-127 P ATPases associated with a variety of cellular activities
GKHACAHP_01651 7.4e-231
GKHACAHP_01652 5.2e-281 L DNA integration
GKHACAHP_01654 1e-198 L Replication initiation factor
GKHACAHP_01655 5.4e-61
GKHACAHP_01656 2e-13
GKHACAHP_01658 2.9e-64
GKHACAHP_01659 7e-262 mloB K Transcriptional regulator
GKHACAHP_01660 2.9e-218 KLT Protein tyrosine kinase
GKHACAHP_01661 3e-62 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
GKHACAHP_01662 4.5e-186 L Transposase
GKHACAHP_01663 1.5e-60 fruR K transcriptional
GKHACAHP_01664 4.3e-36 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
GKHACAHP_01665 5.8e-162 T Diguanylate cyclase
GKHACAHP_01669 5.3e-95 XK27_05505 S Psort location CytoplasmicMembrane, score
GKHACAHP_01670 2.3e-142 P molecular chaperone
GKHACAHP_01671 1.6e-97 S Carbohydrate-binding domain-containing protein Cthe_2159
GKHACAHP_01672 1e-179 XK27_08075 M glycosyl transferase family 2
GKHACAHP_01673 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GKHACAHP_01674 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GKHACAHP_01675 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
GKHACAHP_01676 3.5e-226 rodA D Belongs to the SEDS family
GKHACAHP_01677 3.2e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GKHACAHP_01678 1.3e-108 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
GKHACAHP_01679 5.9e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GKHACAHP_01680 4.8e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GKHACAHP_01681 3.5e-07 Q Methyltransferase domain
GKHACAHP_01682 4e-66 GnaT 2.5.1.16 K acetyltransferase
GKHACAHP_01683 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
GKHACAHP_01684 9.9e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GKHACAHP_01685 2.7e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GKHACAHP_01686 1.3e-125 dnaD
GKHACAHP_01687 1.3e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GKHACAHP_01688 1.8e-06 KT response to antibiotic
GKHACAHP_01689 4.3e-234 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKHACAHP_01690 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GKHACAHP_01691 1.3e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GKHACAHP_01692 1.1e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
GKHACAHP_01693 2.8e-73 argR K Regulates arginine biosynthesis genes
GKHACAHP_01694 1.8e-301 recN L May be involved in recombinational repair of damaged DNA
GKHACAHP_01695 8.7e-148 DegV S DegV family
GKHACAHP_01696 3e-159 ypmR E COG2755 Lysophospholipase L1 and related esterases
GKHACAHP_01697 2e-95 ypmS S Protein conserved in bacteria
GKHACAHP_01698 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GKHACAHP_01700 4e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
GKHACAHP_01701 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GKHACAHP_01702 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GKHACAHP_01703 8.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GKHACAHP_01704 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKHACAHP_01705 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GKHACAHP_01706 0.0 dnaE 2.7.7.7 L DNA polymerase
GKHACAHP_01707 2.6e-186 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GKHACAHP_01708 4.6e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GKHACAHP_01709 0.0 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
GKHACAHP_01710 1.7e-18 S Domain of unknown function (DUF4649)
GKHACAHP_01711 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
GKHACAHP_01712 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
GKHACAHP_01713 8.9e-136 XK27_08845 S abc transporter atp-binding protein
GKHACAHP_01714 1.3e-309 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GKHACAHP_01715 4e-147 estA CE1 S Esterase
GKHACAHP_01716 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
GKHACAHP_01717 3.4e-19 XK27_08880
GKHACAHP_01718 3.9e-75 fld C Flavodoxin
GKHACAHP_01719 2.3e-279 clcA P Chloride transporter, ClC family
GKHACAHP_01720 4.8e-39 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
GKHACAHP_01721 4.3e-212 XK27_05110 P Chloride transporter ClC family
GKHACAHP_01722 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GKHACAHP_01725 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
GKHACAHP_01726 6.5e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GKHACAHP_01727 2.3e-87 ytsP 1.8.4.14 T GAF domain-containing protein
GKHACAHP_01728 5.2e-298 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GKHACAHP_01729 1.6e-171 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GKHACAHP_01730 1.2e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GKHACAHP_01731 1e-275 5.1.3.2 GM Psort location CytoplasmicMembrane, score
GKHACAHP_01732 2.6e-145
GKHACAHP_01733 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
GKHACAHP_01734 2.4e-267 pelF GT4 M Domain of unknown function (DUF3492)
GKHACAHP_01735 4.2e-182 pelG M Putative exopolysaccharide Exporter (EPS-E)
GKHACAHP_01736 2.2e-222 cotH M CotH kinase protein
GKHACAHP_01737 8.7e-96 P VTC domain
GKHACAHP_01738 5.4e-84 S membrane
GKHACAHP_01739 2e-133 G Domain of unknown function (DUF4832)
GKHACAHP_01740 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GKHACAHP_01741 3.7e-11 S Protein of unknown function (DUF1146)
GKHACAHP_01742 5e-232 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GKHACAHP_01743 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
GKHACAHP_01744 4.6e-152 endA F DNA RNA non-specific endonuclease
GKHACAHP_01746 9.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
GKHACAHP_01747 2e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GKHACAHP_01748 8.1e-137 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GKHACAHP_01749 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GKHACAHP_01750 2.3e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GKHACAHP_01751 6.7e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
GKHACAHP_01752 1.4e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GKHACAHP_01753 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GKHACAHP_01754 2.9e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GKHACAHP_01755 1.9e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GKHACAHP_01756 4.9e-61 XK27_08085
GKHACAHP_01757 1.6e-147 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
GKHACAHP_01758 5.5e-138 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
GKHACAHP_01759 5.5e-118 ylfI S tigr01906
GKHACAHP_01760 4.4e-138 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GKHACAHP_01761 2.4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
GKHACAHP_01762 8.5e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
GKHACAHP_01763 1.7e-30 KT response to antibiotic
GKHACAHP_01765 2.8e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GKHACAHP_01766 1e-110 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
GKHACAHP_01767 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GKHACAHP_01768 1.9e-258 S phospholipase Carboxylesterase
GKHACAHP_01769 7.4e-200 yurR 1.4.5.1 E oxidoreductase
GKHACAHP_01770 1.1e-142 zupT P Mediates zinc uptake. May also transport other divalent cations
GKHACAHP_01771 1.7e-142 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GKHACAHP_01772 5.6e-121 trmK 2.1.1.217 S SAM-dependent methyltransferase
GKHACAHP_01773 1.3e-64 gtrA S GtrA-like protein
GKHACAHP_01774 5.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GKHACAHP_01775 3.8e-163 ybbR S Protein conserved in bacteria
GKHACAHP_01776 1.5e-147 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GKHACAHP_01777 1.7e-254 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
GKHACAHP_01778 8.7e-150 cobQ S glutamine amidotransferase
GKHACAHP_01779 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GKHACAHP_01780 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
GKHACAHP_01781 1.6e-39 MA20_06245 S yiaA/B two helix domain
GKHACAHP_01782 0.0 uup S abc transporter atp-binding protein
GKHACAHP_01783 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
GKHACAHP_01784 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
GKHACAHP_01785 3.8e-226 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
GKHACAHP_01786 1e-152 XK27_05675 S Esterase
GKHACAHP_01787 6.1e-162 XK27_05670 S Putative esterase
GKHACAHP_01788 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
GKHACAHP_01789 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GKHACAHP_01790 3e-38 ptsH G phosphocarrier protein Hpr
GKHACAHP_01791 7.4e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
GKHACAHP_01792 1.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
GKHACAHP_01793 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GKHACAHP_01794 6.5e-34 nrdH O Glutaredoxin
GKHACAHP_01795 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKHACAHP_01796 3.8e-184 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GKHACAHP_01797 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GKHACAHP_01798 8.4e-138 divIVA D Cell division initiation protein
GKHACAHP_01799 2.7e-143 ylmH S conserved protein, contains S4-like domain
GKHACAHP_01800 2.9e-30 yggT D integral membrane protein
GKHACAHP_01801 1.8e-99 sepF D cell septum assembly
GKHACAHP_01802 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GKHACAHP_01803 7.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GKHACAHP_01804 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GKHACAHP_01805 1.5e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GKHACAHP_01806 1.2e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GKHACAHP_01807 3.9e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GKHACAHP_01809 0.0 typA T GTP-binding protein TypA
GKHACAHP_01810 2.7e-177 glk 2.7.1.2 G Glucokinase
GKHACAHP_01811 3.5e-26 yqgQ S protein conserved in bacteria
GKHACAHP_01812 2.2e-78 perR P Belongs to the Fur family
GKHACAHP_01813 1.1e-89 dps P Belongs to the Dps family
GKHACAHP_01814 2.7e-104 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
GKHACAHP_01815 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
GKHACAHP_01816 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
GKHACAHP_01817 5.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
GKHACAHP_01818 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GKHACAHP_01819 5.6e-65 S Domain of unknown function (DUF4430)
GKHACAHP_01820 4.1e-73 S Psort location CytoplasmicMembrane, score
GKHACAHP_01821 1.6e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
GKHACAHP_01822 1.7e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
GKHACAHP_01823 8e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
GKHACAHP_01824 5e-119 sirR K iron dependent repressor
GKHACAHP_01825 4e-135 htpX O Belongs to the peptidase M48B family
GKHACAHP_01826 7.7e-92 lemA S LemA family
GKHACAHP_01827 1.7e-174 spd F DNA RNA non-specific endonuclease
GKHACAHP_01828 1.2e-33 2.4.1.21 GT5 M Right handed beta helix region
GKHACAHP_01829 2.8e-32 lytC 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GKHACAHP_01830 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
GKHACAHP_01831 4.9e-146 ycdO P periplasmic lipoprotein involved in iron transport
GKHACAHP_01832 1.8e-231 ycdB P peroxidase
GKHACAHP_01833 5.9e-289 ywbL P COG0672 High-affinity Fe2 Pb2 permease
GKHACAHP_01834 6e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GKHACAHP_01835 3e-24 tatA U protein secretion
GKHACAHP_01836 1.8e-212 msmX P Belongs to the ABC transporter superfamily
GKHACAHP_01837 9.8e-152 malG P ABC transporter (Permease
GKHACAHP_01838 8.2e-249 malF P ABC transporter (Permease
GKHACAHP_01839 9.6e-228 malX G ABC transporter
GKHACAHP_01840 1.7e-171 malR K Transcriptional regulator
GKHACAHP_01841 1.2e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
GKHACAHP_01842 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GKHACAHP_01843 3e-39
GKHACAHP_01844 5.5e-186 lplA 6.3.1.20 H Lipoate-protein ligase
GKHACAHP_01845 3.5e-194 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
GKHACAHP_01846 0.0 pepN 3.4.11.2 E aminopeptidase
GKHACAHP_01847 7.1e-113 phoU P Plays a role in the regulation of phosphate uptake
GKHACAHP_01848 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKHACAHP_01849 1.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GKHACAHP_01850 1.5e-155 pstA P phosphate transport system permease
GKHACAHP_01851 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
GKHACAHP_01852 1.1e-156 pstS P phosphate
GKHACAHP_01853 2e-252 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
GKHACAHP_01854 5.9e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
GKHACAHP_01855 1e-44 yktA S Belongs to the UPF0223 family
GKHACAHP_01856 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GKHACAHP_01857 1.5e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GKHACAHP_01858 3e-148 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GKHACAHP_01859 2.5e-245 XK27_04775 S hemerythrin HHE cation binding domain
GKHACAHP_01860 2.3e-34 M1-755 P Hemerythrin HHE cation binding domain protein
GKHACAHP_01861 1.4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
GKHACAHP_01862 3.6e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GKHACAHP_01863 2.5e-138 S haloacid dehalogenase-like hydrolase
GKHACAHP_01864 3.3e-239 metY 2.5.1.49 E o-acetylhomoserine
GKHACAHP_01865 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GKHACAHP_01866 1.2e-239 agcS E (Alanine) symporter
GKHACAHP_01867 2.3e-243 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GKHACAHP_01868 1.6e-174 bglC K Transcriptional regulator
GKHACAHP_01869 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
GKHACAHP_01870 4.9e-82 yecS P ABC transporter (Permease
GKHACAHP_01871 2.5e-147 yckB ET Belongs to the bacterial solute-binding protein 3 family
GKHACAHP_01872 2.9e-236 nylA 3.5.1.4 J Belongs to the amidase family
GKHACAHP_01873 9.8e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GKHACAHP_01874 1e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GKHACAHP_01875 1e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GKHACAHP_01876 3.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GKHACAHP_01877 7.5e-92 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
GKHACAHP_01878 4.8e-132 S TraX protein
GKHACAHP_01879 2.5e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
GKHACAHP_01880 4.5e-259 S Psort location CytoplasmicMembrane, score
GKHACAHP_01881 1.2e-231 dinF V Mate efflux family protein
GKHACAHP_01882 1.3e-176 yclQ P ABC-type enterochelin transport system, periplasmic component
GKHACAHP_01883 1.2e-154 S von Willebrand factor (vWF) type A domain
GKHACAHP_01884 0.0 V Type III restriction enzyme, res subunit
GKHACAHP_01885 1.1e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
GKHACAHP_01886 7e-242 S the current gene model (or a revised gene model) may contain a frame shift
GKHACAHP_01887 3.4e-186 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
GKHACAHP_01888 2.3e-193 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GKHACAHP_01889 4.9e-157 czcD P cation diffusion facilitator family transporter
GKHACAHP_01890 1e-93 K Transcriptional regulator, TetR family
GKHACAHP_01891 3.1e-70 S Protein of unknown function with HXXEE motif
GKHACAHP_01892 4.2e-45

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)