ORF_ID e_value Gene_name EC_number CAZy COGs Description
KLGPHHPM_00007 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KLGPHHPM_00008 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
KLGPHHPM_00009 7.7e-133 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KLGPHHPM_00010 6.8e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
KLGPHHPM_00011 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLGPHHPM_00012 1.3e-16 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KLGPHHPM_00013 1.9e-66 2.7.13.3 T GHKL domain
KLGPHHPM_00014 4.8e-132 ponA V Beta-lactamase enzyme family
KLGPHHPM_00015 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
KLGPHHPM_00016 5.3e-215 uhpT EGP Major facilitator Superfamily
KLGPHHPM_00017 2.6e-255 ytjP 3.5.1.18 E Dipeptidase
KLGPHHPM_00018 8.2e-274 arcD S C4-dicarboxylate anaerobic carrier
KLGPHHPM_00019 7.4e-40 L Integrase core domain
KLGPHHPM_00020 1.1e-40
KLGPHHPM_00022 3.5e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KLGPHHPM_00023 5.6e-277 pepV 3.5.1.18 E dipeptidase PepV
KLGPHHPM_00024 5.2e-84 uspA T Belongs to the universal stress protein A family
KLGPHHPM_00025 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLGPHHPM_00026 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
KLGPHHPM_00027 3.8e-113
KLGPHHPM_00028 1.8e-184 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
KLGPHHPM_00029 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLGPHHPM_00030 2.1e-32
KLGPHHPM_00031 2.6e-118 S CAAX protease self-immunity
KLGPHHPM_00032 1.6e-42
KLGPHHPM_00034 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KLGPHHPM_00035 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
KLGPHHPM_00036 1.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
KLGPHHPM_00037 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLGPHHPM_00038 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
KLGPHHPM_00039 9.3e-217 folP 2.5.1.15 H dihydropteroate synthase
KLGPHHPM_00040 1.8e-43
KLGPHHPM_00041 3.3e-40
KLGPHHPM_00043 1e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLGPHHPM_00044 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLGPHHPM_00045 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KLGPHHPM_00046 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KLGPHHPM_00047 3.5e-40 yheA S Belongs to the UPF0342 family
KLGPHHPM_00048 1.8e-220 yhaO L Ser Thr phosphatase family protein
KLGPHHPM_00049 0.0 L AAA domain
KLGPHHPM_00050 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KLGPHHPM_00052 1.2e-76 hit FG histidine triad
KLGPHHPM_00053 4.3e-135 ecsA V ABC transporter, ATP-binding protein
KLGPHHPM_00054 5.1e-218 ecsB U ABC transporter
KLGPHHPM_00055 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KLGPHHPM_00056 7.7e-27 S YSIRK type signal peptide
KLGPHHPM_00057 3.8e-66 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
KLGPHHPM_00058 5.2e-254 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
KLGPHHPM_00059 1.3e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KLGPHHPM_00060 8.8e-184 iolS C Aldo keto reductase
KLGPHHPM_00061 1.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
KLGPHHPM_00062 7.5e-58 ytzB S Small secreted protein
KLGPHHPM_00063 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KLGPHHPM_00064 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLGPHHPM_00065 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
KLGPHHPM_00066 1.3e-21 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
KLGPHHPM_00067 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KLGPHHPM_00068 1.9e-119 ybhL S Belongs to the BI1 family
KLGPHHPM_00070 8.9e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
KLGPHHPM_00071 1.9e-130 IQ Dehydrogenase reductase
KLGPHHPM_00072 4.1e-37 S Uncharacterised protein family (UPF0236)
KLGPHHPM_00073 9.2e-149 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLGPHHPM_00074 5.6e-79 pncA Q Isochorismatase family
KLGPHHPM_00075 7.9e-61 pldB 3.1.1.5 I Serine aminopeptidase, S33
KLGPHHPM_00077 1.7e-25 K TRANSCRIPTIONal
KLGPHHPM_00078 2.4e-86 cotH M CotH kinase protein
KLGPHHPM_00080 3.4e-36 S Bacteriophage holin family
KLGPHHPM_00081 4.4e-55 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KLGPHHPM_00082 7.3e-203 3.5.1.104 M hydrolase, family 25
KLGPHHPM_00083 9.8e-44 S Bacteriophage abortive infection AbiH
KLGPHHPM_00085 2e-112 pi136 S Caudovirus prohead serine protease
KLGPHHPM_00086 7.1e-239 S Phage portal protein
KLGPHHPM_00089 0.0 terL S overlaps another CDS with the same product name
KLGPHHPM_00090 2e-77 terS L Phage terminase, small subunit
KLGPHHPM_00091 8.3e-151 L HNH nucleases
KLGPHHPM_00092 1.2e-08
KLGPHHPM_00094 3.2e-83 arpU S Phage transcriptional regulator, ArpU family
KLGPHHPM_00101 2.8e-134
KLGPHHPM_00102 2.4e-69
KLGPHHPM_00104 1.8e-124 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
KLGPHHPM_00105 1.4e-189 L Belongs to the 'phage' integrase family
KLGPHHPM_00106 1.4e-119 L DnaD domain protein
KLGPHHPM_00109 1e-14
KLGPHHPM_00114 6.3e-10 K Helix-turn-helix XRE-family like proteins
KLGPHHPM_00115 2.3e-79 3.4.21.88 K Peptidase S24-like
KLGPHHPM_00116 9.3e-09
KLGPHHPM_00119 1.7e-20
KLGPHHPM_00121 1.5e-38
KLGPHHPM_00123 8.7e-122 V Abi-like protein
KLGPHHPM_00124 3.5e-224 3.6.4.12 L Belongs to the 'phage' integrase family
KLGPHHPM_00125 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KLGPHHPM_00126 1.5e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KLGPHHPM_00127 0.0 dnaK O Heat shock 70 kDa protein
KLGPHHPM_00128 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KLGPHHPM_00129 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KLGPHHPM_00130 5.8e-64
KLGPHHPM_00131 6.5e-202 ykiI
KLGPHHPM_00132 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
KLGPHHPM_00133 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KLGPHHPM_00134 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KLGPHHPM_00135 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KLGPHHPM_00136 9.1e-62 S Domain of unknown function (DUF4828)
KLGPHHPM_00137 7.7e-191 mocA S Oxidoreductase
KLGPHHPM_00138 2.6e-228 yfmL L DEAD DEAH box helicase
KLGPHHPM_00140 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLGPHHPM_00141 9.3e-56
KLGPHHPM_00142 2.3e-67 gtcA S Teichoic acid glycosylation protein
KLGPHHPM_00143 6.1e-79 fld C Flavodoxin
KLGPHHPM_00144 6.5e-167 map 3.4.11.18 E Methionine Aminopeptidase
KLGPHHPM_00145 1.7e-220 arcT 2.6.1.1 E Aminotransferase
KLGPHHPM_00146 3.6e-255 E Arginine ornithine antiporter
KLGPHHPM_00147 1.1e-281 yjeM E Amino Acid
KLGPHHPM_00148 3.2e-153 yihY S Belongs to the UPF0761 family
KLGPHHPM_00149 6.6e-34 S Protein of unknown function (DUF2922)
KLGPHHPM_00150 4.9e-31
KLGPHHPM_00151 7.4e-125 recX 2.4.1.337 GT4 S Regulatory protein RecX
KLGPHHPM_00152 3.3e-146 cps1D M Domain of unknown function (DUF4422)
KLGPHHPM_00153 2.4e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
KLGPHHPM_00154 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
KLGPHHPM_00155 0.0 2.7.7.6 M Peptidase family M23
KLGPHHPM_00156 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KLGPHHPM_00157 5.3e-83 K Bacterial regulatory proteins, tetR family
KLGPHHPM_00158 4.3e-55 yphJ 4.1.1.44 S decarboxylase
KLGPHHPM_00159 2e-74 P FAD-binding domain
KLGPHHPM_00160 4.7e-109 S Peptidase propeptide and YPEB domain
KLGPHHPM_00161 6.4e-238 T GHKL domain
KLGPHHPM_00162 2.1e-120 T Transcriptional regulatory protein, C terminal
KLGPHHPM_00163 3.9e-27 mleP3 S Membrane transport protein
KLGPHHPM_00164 4.4e-100 L Helix-turn-helix domain
KLGPHHPM_00165 2.5e-158 L hmm pf00665
KLGPHHPM_00166 7.1e-13 UW LPXTG-motif cell wall anchor domain protein
KLGPHHPM_00167 6.5e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KLGPHHPM_00168 4.3e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
KLGPHHPM_00169 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KLGPHHPM_00170 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KLGPHHPM_00171 8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KLGPHHPM_00172 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KLGPHHPM_00173 1.3e-137 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KLGPHHPM_00174 5.5e-217 patA 2.6.1.1 E Aminotransferase
KLGPHHPM_00175 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KLGPHHPM_00176 8.5e-84 KT Putative sugar diacid recognition
KLGPHHPM_00177 2.2e-219 EG GntP family permease
KLGPHHPM_00178 1e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KLGPHHPM_00179 7.7e-58
KLGPHHPM_00181 1.2e-133 mltD CBM50 M NlpC P60 family protein
KLGPHHPM_00182 5.7e-29
KLGPHHPM_00183 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
KLGPHHPM_00184 9.8e-32 ykzG S Belongs to the UPF0356 family
KLGPHHPM_00185 2.4e-78
KLGPHHPM_00186 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KLGPHHPM_00187 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
KLGPHHPM_00188 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
KLGPHHPM_00189 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KLGPHHPM_00190 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
KLGPHHPM_00191 1.4e-47 yktA S Belongs to the UPF0223 family
KLGPHHPM_00192 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
KLGPHHPM_00193 0.0 typA T GTP-binding protein TypA
KLGPHHPM_00194 2e-222 ftsW D Belongs to the SEDS family
KLGPHHPM_00195 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
KLGPHHPM_00196 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
KLGPHHPM_00197 3.3e-89 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KLGPHHPM_00198 2.5e-197 ylbL T Belongs to the peptidase S16 family
KLGPHHPM_00199 2.6e-80 comEA L Competence protein ComEA
KLGPHHPM_00200 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
KLGPHHPM_00201 0.0 comEC S Competence protein ComEC
KLGPHHPM_00202 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
KLGPHHPM_00203 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
KLGPHHPM_00204 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KLGPHHPM_00205 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLGPHHPM_00206 3.5e-163 S Tetratricopeptide repeat
KLGPHHPM_00207 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KLGPHHPM_00208 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KLGPHHPM_00209 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KLGPHHPM_00210 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
KLGPHHPM_00211 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
KLGPHHPM_00212 1.3e-08
KLGPHHPM_00213 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KLGPHHPM_00214 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KLGPHHPM_00215 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KLGPHHPM_00216 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KLGPHHPM_00217 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KLGPHHPM_00218 7.8e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KLGPHHPM_00219 2.1e-87
KLGPHHPM_00221 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLGPHHPM_00222 2.8e-213 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
KLGPHHPM_00223 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KLGPHHPM_00224 1.3e-35 ynzC S UPF0291 protein
KLGPHHPM_00225 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
KLGPHHPM_00226 4.6e-117 plsC 2.3.1.51 I Acyltransferase
KLGPHHPM_00227 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
KLGPHHPM_00228 5.4e-49 yazA L GIY-YIG catalytic domain protein
KLGPHHPM_00229 9.8e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLGPHHPM_00230 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
KLGPHHPM_00231 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KLGPHHPM_00232 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KLGPHHPM_00233 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KLGPHHPM_00234 3.5e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KLGPHHPM_00235 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
KLGPHHPM_00236 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
KLGPHHPM_00237 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KLGPHHPM_00238 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLGPHHPM_00239 4.4e-100 L Helix-turn-helix domain
KLGPHHPM_00240 2.5e-158 L hmm pf00665
KLGPHHPM_00241 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KLGPHHPM_00242 3e-34
KLGPHHPM_00243 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
KLGPHHPM_00244 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
KLGPHHPM_00245 2.6e-86 ygfC K transcriptional regulator (TetR family)
KLGPHHPM_00246 2.1e-183 hrtB V ABC transporter permease
KLGPHHPM_00247 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
KLGPHHPM_00248 0.0 yhcA V ABC transporter, ATP-binding protein
KLGPHHPM_00249 4.6e-38
KLGPHHPM_00250 3.5e-49 czrA K Transcriptional regulator, ArsR family
KLGPHHPM_00251 2e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLGPHHPM_00252 5.1e-173 scrR K Transcriptional regulator, LacI family
KLGPHHPM_00253 3e-24
KLGPHHPM_00254 8.2e-103
KLGPHHPM_00255 2.6e-214 yttB EGP Major facilitator Superfamily
KLGPHHPM_00256 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KLGPHHPM_00257 2.2e-87
KLGPHHPM_00258 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
KLGPHHPM_00259 6.6e-262 S Putative peptidoglycan binding domain
KLGPHHPM_00262 1.3e-260 3.4.24.40 M Peptidase family M23
KLGPHHPM_00263 6e-157 S Phage tail protein
KLGPHHPM_00264 0.0 M Phage tail tape measure protein TP901
KLGPHHPM_00265 1.5e-19
KLGPHHPM_00266 6e-23
KLGPHHPM_00267 2.2e-116
KLGPHHPM_00268 9.5e-71
KLGPHHPM_00269 1.2e-45 S Bacteriophage HK97-gp10, putative tail-component
KLGPHHPM_00270 1.9e-39 S Phage head-tail joining protein
KLGPHHPM_00271 3.4e-65 S Phage gp6-like head-tail connector protein
KLGPHHPM_00272 4.2e-139 S peptidase activity
KLGPHHPM_00273 1.4e-20
KLGPHHPM_00274 0.0 L Helicase C-terminal domain protein
KLGPHHPM_00275 9.5e-47 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
KLGPHHPM_00276 5.9e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLGPHHPM_00277 5.1e-187 yegS 2.7.1.107 G Lipid kinase
KLGPHHPM_00278 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLGPHHPM_00279 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KLGPHHPM_00280 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KLGPHHPM_00281 2.1e-202 camS S sex pheromone
KLGPHHPM_00282 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KLGPHHPM_00283 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KLGPHHPM_00284 5.7e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KLGPHHPM_00285 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KLGPHHPM_00286 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
KLGPHHPM_00287 6.1e-140 IQ reductase
KLGPHHPM_00288 6.7e-278 pipD E Dipeptidase
KLGPHHPM_00289 0.0 yjbQ P TrkA C-terminal domain protein
KLGPHHPM_00290 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
KLGPHHPM_00291 2e-288 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KLGPHHPM_00292 1.3e-82
KLGPHHPM_00294 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
KLGPHHPM_00295 5.2e-309 lmrA 3.6.3.44 V ABC transporter
KLGPHHPM_00297 6.8e-130 K response regulator
KLGPHHPM_00298 0.0 vicK 2.7.13.3 T Histidine kinase
KLGPHHPM_00299 2.1e-246 yycH S YycH protein
KLGPHHPM_00300 2.7e-149 yycI S YycH protein
KLGPHHPM_00301 4.5e-154 vicX 3.1.26.11 S domain protein
KLGPHHPM_00302 2.5e-215 htrA 3.4.21.107 O serine protease
KLGPHHPM_00303 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
KLGPHHPM_00304 1.7e-179 ABC-SBP S ABC transporter
KLGPHHPM_00305 1.4e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KLGPHHPM_00306 4.5e-48 L PFAM transposase IS200-family protein
KLGPHHPM_00307 7.4e-134 K LysR substrate binding domain
KLGPHHPM_00308 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KLGPHHPM_00309 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KLGPHHPM_00310 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KLGPHHPM_00311 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KLGPHHPM_00312 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KLGPHHPM_00313 9.6e-115 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
KLGPHHPM_00314 6.7e-95 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KLGPHHPM_00315 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
KLGPHHPM_00316 4.9e-177 K AI-2E family transporter
KLGPHHPM_00317 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
KLGPHHPM_00318 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KLGPHHPM_00319 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
KLGPHHPM_00320 4.3e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KLGPHHPM_00321 4.7e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KLGPHHPM_00322 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KLGPHHPM_00323 9.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KLGPHHPM_00324 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLGPHHPM_00325 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLGPHHPM_00326 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KLGPHHPM_00327 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KLGPHHPM_00328 4e-195 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KLGPHHPM_00329 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KLGPHHPM_00330 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KLGPHHPM_00331 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
KLGPHHPM_00332 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLGPHHPM_00333 9.7e-173
KLGPHHPM_00334 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KLGPHHPM_00335 1.6e-52 azlD S branched-chain amino acid
KLGPHHPM_00336 3.7e-136 azlC E AzlC protein
KLGPHHPM_00337 4.2e-198 hpk31 2.7.13.3 T Histidine kinase
KLGPHHPM_00338 1.2e-123 K response regulator
KLGPHHPM_00339 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLGPHHPM_00340 2.8e-171 deoR K sugar-binding domain protein
KLGPHHPM_00341 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KLGPHHPM_00342 1.1e-234 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
KLGPHHPM_00343 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KLGPHHPM_00344 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KLGPHHPM_00345 2.2e-134 XK27_01040 S Protein of unknown function (DUF1129)
KLGPHHPM_00346 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KLGPHHPM_00347 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
KLGPHHPM_00348 1.7e-154 spo0J K Belongs to the ParB family
KLGPHHPM_00349 2.6e-138 soj D Sporulation initiation inhibitor
KLGPHHPM_00350 9.6e-151 noc K Belongs to the ParB family
KLGPHHPM_00351 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KLGPHHPM_00352 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
KLGPHHPM_00353 5.6e-169 rihC 3.2.2.1 F Nucleoside
KLGPHHPM_00354 2.3e-218 nupG F Nucleoside transporter
KLGPHHPM_00355 7.2e-221 cycA E Amino acid permease
KLGPHHPM_00357 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLGPHHPM_00358 1.2e-264 glnP P ABC transporter
KLGPHHPM_00359 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KLGPHHPM_00360 2.5e-158 L hmm pf00665
KLGPHHPM_00361 4.4e-100 L Helix-turn-helix domain
KLGPHHPM_00362 1.1e-217 S CAAX protease self-immunity
KLGPHHPM_00363 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KLGPHHPM_00364 3.5e-42
KLGPHHPM_00365 9.2e-264 pipD E Dipeptidase
KLGPHHPM_00366 5.2e-203 coiA 3.6.4.12 S Competence protein
KLGPHHPM_00367 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
KLGPHHPM_00368 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KLGPHHPM_00369 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KLGPHHPM_00370 4.1e-37 S Uncharacterised protein family (UPF0236)
KLGPHHPM_00371 5.4e-158 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLGPHHPM_00372 0.0 G Peptidase_C39 like family
KLGPHHPM_00373 2.1e-25
KLGPHHPM_00374 0.0 ganB 3.2.1.89 G arabinogalactan
KLGPHHPM_00375 3.6e-218 glf 5.4.99.9 M UDP-galactopyranose mutase
KLGPHHPM_00376 2.3e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
KLGPHHPM_00377 1.4e-75 M transferase activity, transferring glycosyl groups
KLGPHHPM_00378 1.3e-88 cps3F
KLGPHHPM_00379 6.6e-28 M biosynthesis protein
KLGPHHPM_00380 2e-76 rgpB GT2 M Glycosyl transferase family 2
KLGPHHPM_00381 3.4e-66 S Glycosyltransferase like family
KLGPHHPM_00382 3.7e-80 glfT1 1.1.1.133 S Glycosyltransferase like family 2
KLGPHHPM_00383 2e-29 S Acyltransferase family
KLGPHHPM_00384 6.5e-37 S Acyltransferase family
KLGPHHPM_00385 2.8e-35
KLGPHHPM_00386 3.2e-72 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KLGPHHPM_00387 2.6e-164 ykoT GT2 M Glycosyl transferase family 2
KLGPHHPM_00388 7.1e-63 S integral membrane protein
KLGPHHPM_00389 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KLGPHHPM_00390 3.6e-17 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
KLGPHHPM_00392 2.3e-78 O Bacterial dnaA protein
KLGPHHPM_00393 2.3e-162
KLGPHHPM_00394 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
KLGPHHPM_00395 2.8e-170 S AI-2E family transporter
KLGPHHPM_00396 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
KLGPHHPM_00397 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
KLGPHHPM_00398 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
KLGPHHPM_00399 4.8e-88 GM epimerase
KLGPHHPM_00400 1.7e-154 ypdB V (ABC) transporter
KLGPHHPM_00401 6.2e-241 yhdP S Transporter associated domain
KLGPHHPM_00402 9.9e-85 nrdI F Belongs to the NrdI family
KLGPHHPM_00403 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
KLGPHHPM_00404 3.1e-193 yeaN P Transporter, major facilitator family protein
KLGPHHPM_00405 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KLGPHHPM_00406 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KLGPHHPM_00407 5.5e-28
KLGPHHPM_00408 5.6e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KLGPHHPM_00409 5.5e-40 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KLGPHHPM_00410 2.2e-156 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KLGPHHPM_00411 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
KLGPHHPM_00412 1.1e-90 bioY S BioY family
KLGPHHPM_00413 5.6e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KLGPHHPM_00414 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
KLGPHHPM_00415 5.6e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KLGPHHPM_00416 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KLGPHHPM_00417 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KLGPHHPM_00418 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
KLGPHHPM_00419 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KLGPHHPM_00420 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KLGPHHPM_00421 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KLGPHHPM_00422 1.9e-206 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KLGPHHPM_00423 1.2e-219 patA 2.6.1.1 E Aminotransferase
KLGPHHPM_00424 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
KLGPHHPM_00425 2e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KLGPHHPM_00426 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KLGPHHPM_00427 3e-30 S Protein of unknown function (DUF2929)
KLGPHHPM_00428 0.0 dnaE 2.7.7.7 L DNA polymerase
KLGPHHPM_00429 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KLGPHHPM_00430 2.3e-167 cvfB S S1 domain
KLGPHHPM_00431 1.2e-163 xerD D recombinase XerD
KLGPHHPM_00432 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KLGPHHPM_00433 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KLGPHHPM_00434 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KLGPHHPM_00435 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KLGPHHPM_00436 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KLGPHHPM_00437 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
KLGPHHPM_00438 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
KLGPHHPM_00439 8.5e-14 M Lysin motif
KLGPHHPM_00440 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KLGPHHPM_00441 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KLGPHHPM_00442 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KLGPHHPM_00443 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KLGPHHPM_00444 1.5e-236 S Tetratricopeptide repeat protein
KLGPHHPM_00445 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KLGPHHPM_00446 0.0 yfmR S ABC transporter, ATP-binding protein
KLGPHHPM_00447 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KLGPHHPM_00448 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KLGPHHPM_00449 5.3e-113 hlyIII S protein, hemolysin III
KLGPHHPM_00450 1.7e-151 DegV S EDD domain protein, DegV family
KLGPHHPM_00451 9.5e-172 ypmR E lipolytic protein G-D-S-L family
KLGPHHPM_00452 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
KLGPHHPM_00453 4.4e-35 yozE S Belongs to the UPF0346 family
KLGPHHPM_00454 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KLGPHHPM_00455 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KLGPHHPM_00456 2.4e-161 dprA LU DNA protecting protein DprA
KLGPHHPM_00457 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KLGPHHPM_00458 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
KLGPHHPM_00459 1.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KLGPHHPM_00460 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLGPHHPM_00461 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KLGPHHPM_00462 1.7e-84 F NUDIX domain
KLGPHHPM_00463 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
KLGPHHPM_00464 4.1e-37 S Uncharacterised protein family (UPF0236)
KLGPHHPM_00465 8.6e-59 lsa S ABC transporter
KLGPHHPM_00466 7.5e-168 lsa S ABC transporter
KLGPHHPM_00467 3.5e-134 I alpha/beta hydrolase fold
KLGPHHPM_00468 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
KLGPHHPM_00469 2.6e-224 G Belongs to the glycosyl hydrolase family 6
KLGPHHPM_00470 1.3e-96 S NADPH-dependent FMN reductase
KLGPHHPM_00471 7.4e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLGPHHPM_00472 2.6e-68 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KLGPHHPM_00473 5.7e-82 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KLGPHHPM_00474 9.1e-229 mntH P H( )-stimulated, divalent metal cation uptake system
KLGPHHPM_00475 1.2e-81 Q Methyltransferase
KLGPHHPM_00476 1.4e-116 ktrA P domain protein
KLGPHHPM_00477 4.9e-238 ktrB P Potassium uptake protein
KLGPHHPM_00478 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
KLGPHHPM_00479 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
KLGPHHPM_00480 1.4e-217 G Glycosyl hydrolases family 8
KLGPHHPM_00481 2.2e-243 ydaM M Glycosyl transferase
KLGPHHPM_00482 1.2e-141
KLGPHHPM_00483 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
KLGPHHPM_00484 2e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KLGPHHPM_00485 5.5e-153 pstA P Phosphate transport system permease protein PstA
KLGPHHPM_00486 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
KLGPHHPM_00487 8.6e-159 pstS P Phosphate
KLGPHHPM_00488 1.5e-132 K Transcriptional regulatory protein, C-terminal domain protein
KLGPHHPM_00489 4.1e-37 S Uncharacterised protein family (UPF0236)
KLGPHHPM_00490 2.1e-208 rny S Endoribonuclease that initiates mRNA decay
KLGPHHPM_00491 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KLGPHHPM_00492 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KLGPHHPM_00493 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KLGPHHPM_00494 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KLGPHHPM_00495 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KLGPHHPM_00496 2.8e-31 yajC U Preprotein translocase
KLGPHHPM_00497 3.6e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
KLGPHHPM_00498 6.4e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KLGPHHPM_00499 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KLGPHHPM_00500 4.1e-43 yrzL S Belongs to the UPF0297 family
KLGPHHPM_00501 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KLGPHHPM_00502 6.1e-48 yrzB S Belongs to the UPF0473 family
KLGPHHPM_00503 1e-85 cvpA S Colicin V production protein
KLGPHHPM_00504 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KLGPHHPM_00505 6.1e-54 trxA O Belongs to the thioredoxin family
KLGPHHPM_00506 1.3e-96 yslB S Protein of unknown function (DUF2507)
KLGPHHPM_00507 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KLGPHHPM_00508 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KLGPHHPM_00509 4.4e-94 S Phosphoesterase
KLGPHHPM_00510 3.6e-76 ykuL S (CBS) domain
KLGPHHPM_00511 5.2e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
KLGPHHPM_00512 3.4e-147 ykuT M mechanosensitive ion channel
KLGPHHPM_00513 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KLGPHHPM_00514 1.3e-25
KLGPHHPM_00515 1.2e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KLGPHHPM_00516 1.4e-181 ccpA K catabolite control protein A
KLGPHHPM_00517 1.9e-134
KLGPHHPM_00518 3.5e-132 yebC K Transcriptional regulatory protein
KLGPHHPM_00519 2.6e-180 comGA NU Type II IV secretion system protein
KLGPHHPM_00520 9.5e-181 comGB NU type II secretion system
KLGPHHPM_00521 7.1e-47 comGC U competence protein ComGC
KLGPHHPM_00522 8.3e-78 NU general secretion pathway protein
KLGPHHPM_00523 2.7e-40
KLGPHHPM_00524 6.3e-70
KLGPHHPM_00526 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
KLGPHHPM_00527 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KLGPHHPM_00528 2.2e-113 S Calcineurin-like phosphoesterase
KLGPHHPM_00529 1.3e-93 yutD S Protein of unknown function (DUF1027)
KLGPHHPM_00530 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KLGPHHPM_00531 2.4e-105 S Protein of unknown function (DUF1461)
KLGPHHPM_00532 5.5e-110 dedA S SNARE-like domain protein
KLGPHHPM_00533 1.3e-46
KLGPHHPM_00535 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLGPHHPM_00536 7.9e-158 amtB P ammonium transporter
KLGPHHPM_00537 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
KLGPHHPM_00538 1.4e-90 S B3 4 domain
KLGPHHPM_00539 2.1e-91
KLGPHHPM_00540 4.8e-122 pnb C nitroreductase
KLGPHHPM_00541 2e-74 ogt 2.1.1.63 L Methyltransferase
KLGPHHPM_00542 3.2e-171 XK27_00915 C Luciferase-like monooxygenase
KLGPHHPM_00543 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
KLGPHHPM_00544 7.3e-69 S Protein of unknown function (DUF3021)
KLGPHHPM_00545 6.4e-78 K LytTr DNA-binding domain
KLGPHHPM_00546 2.6e-91 K Acetyltransferase (GNAT) family
KLGPHHPM_00547 3.1e-21
KLGPHHPM_00548 1.7e-120 ybhL S Belongs to the BI1 family
KLGPHHPM_00549 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
KLGPHHPM_00550 9.3e-197 S Protein of unknown function (DUF3114)
KLGPHHPM_00551 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KLGPHHPM_00552 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLGPHHPM_00553 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KLGPHHPM_00554 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KLGPHHPM_00555 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
KLGPHHPM_00556 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KLGPHHPM_00557 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
KLGPHHPM_00558 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
KLGPHHPM_00559 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
KLGPHHPM_00560 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KLGPHHPM_00561 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KLGPHHPM_00562 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
KLGPHHPM_00563 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KLGPHHPM_00564 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KLGPHHPM_00565 1.9e-109 L Transposase
KLGPHHPM_00566 1.2e-35 L Transposase
KLGPHHPM_00567 2.1e-191 L Transposase
KLGPHHPM_00568 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KLGPHHPM_00569 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KLGPHHPM_00570 4.2e-261 nox C NADH oxidase
KLGPHHPM_00571 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
KLGPHHPM_00572 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
KLGPHHPM_00573 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
KLGPHHPM_00574 3.8e-167 yvgN C Aldo keto reductase
KLGPHHPM_00575 6.6e-136 puuD S peptidase C26
KLGPHHPM_00576 5.1e-66 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KLGPHHPM_00577 2e-63 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
KLGPHHPM_00578 1e-207 yfeO P Voltage gated chloride channel
KLGPHHPM_00579 5.3e-226 sptS 2.7.13.3 T Histidine kinase
KLGPHHPM_00580 3.3e-118 K response regulator
KLGPHHPM_00581 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
KLGPHHPM_00582 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
KLGPHHPM_00583 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
KLGPHHPM_00584 1.1e-256 malT G Major Facilitator
KLGPHHPM_00585 4.1e-37 S Uncharacterised protein family (UPF0236)
KLGPHHPM_00587 5.5e-220 M Glycosyl transferase family group 2
KLGPHHPM_00588 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KLGPHHPM_00589 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KLGPHHPM_00590 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KLGPHHPM_00591 5.7e-38
KLGPHHPM_00592 1e-107 L Bacterial dnaA protein
KLGPHHPM_00593 1.4e-09 L Bacterial dnaA protein
KLGPHHPM_00594 1e-116 L Integrase core domain
KLGPHHPM_00595 2.9e-99 L Integrase core domain
KLGPHHPM_00597 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
KLGPHHPM_00598 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
KLGPHHPM_00599 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KLGPHHPM_00600 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KLGPHHPM_00601 1.2e-10 S Protein of unknown function (DUF4044)
KLGPHHPM_00602 7.3e-56
KLGPHHPM_00603 3.1e-77 mraZ K Belongs to the MraZ family
KLGPHHPM_00604 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KLGPHHPM_00605 2.6e-56 ftsL D Cell division protein FtsL
KLGPHHPM_00606 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KLGPHHPM_00607 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KLGPHHPM_00608 5.5e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KLGPHHPM_00609 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KLGPHHPM_00610 2.5e-147 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KLGPHHPM_00611 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KLGPHHPM_00612 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KLGPHHPM_00613 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KLGPHHPM_00614 3.2e-40 yggT S YGGT family
KLGPHHPM_00615 5.1e-142 ylmH S S4 domain protein
KLGPHHPM_00616 1.9e-42 divIVA D DivIVA domain protein
KLGPHHPM_00617 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KLGPHHPM_00618 4.2e-32 cspA K Cold shock protein
KLGPHHPM_00619 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
KLGPHHPM_00621 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KLGPHHPM_00622 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
KLGPHHPM_00623 1.3e-57 XK27_04120 S Putative amino acid metabolism
KLGPHHPM_00624 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KLGPHHPM_00625 2.4e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
KLGPHHPM_00626 9e-119 S Repeat protein
KLGPHHPM_00627 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KLGPHHPM_00628 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLGPHHPM_00630 4.4e-100 L Helix-turn-helix domain
KLGPHHPM_00631 2.5e-158 L hmm pf00665
KLGPHHPM_00632 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
KLGPHHPM_00633 8.7e-140 L hmm pf00665
KLGPHHPM_00634 1.7e-105 L Helix-turn-helix domain
KLGPHHPM_00635 8.6e-202 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
KLGPHHPM_00636 1.3e-130 2.4.1.52 GT4 M Glycosyl transferases group 1
KLGPHHPM_00637 7e-14 L Integrase core domain
KLGPHHPM_00638 2e-192 L Integrase core domain
KLGPHHPM_00639 8.2e-126 O Bacterial dnaA protein
KLGPHHPM_00640 3.2e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
KLGPHHPM_00643 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KLGPHHPM_00644 1.4e-197 XK27_09615 S reductase
KLGPHHPM_00645 4.9e-102 nqr 1.5.1.36 S reductase
KLGPHHPM_00646 8.2e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KLGPHHPM_00647 1.2e-189 1.3.5.4 C FAD binding domain
KLGPHHPM_00648 1.6e-51 K LysR substrate binding domain
KLGPHHPM_00649 1.1e-178 K Transcriptional regulator, LacI family
KLGPHHPM_00650 4.7e-260 G Major Facilitator
KLGPHHPM_00651 1e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KLGPHHPM_00652 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KLGPHHPM_00653 5.2e-267 G Major Facilitator
KLGPHHPM_00654 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
KLGPHHPM_00655 7.1e-277 M domain protein
KLGPHHPM_00656 4.6e-261 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
KLGPHHPM_00657 3.4e-267 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
KLGPHHPM_00658 2.2e-72
KLGPHHPM_00659 6.2e-76 K Transcriptional regulator, TetR family
KLGPHHPM_00660 1e-235 pbuG S permease
KLGPHHPM_00661 4.1e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
KLGPHHPM_00662 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
KLGPHHPM_00663 2.5e-135 S Belongs to the UPF0246 family
KLGPHHPM_00664 2.5e-138 S Membrane
KLGPHHPM_00665 8.1e-75 4.4.1.5 E Glyoxalase
KLGPHHPM_00666 1.5e-21
KLGPHHPM_00667 7.1e-86 yueI S Protein of unknown function (DUF1694)
KLGPHHPM_00668 1.7e-235 rarA L recombination factor protein RarA
KLGPHHPM_00669 4.4e-46
KLGPHHPM_00670 4.3e-83 usp6 T universal stress protein
KLGPHHPM_00671 2.8e-207 araR K Transcriptional regulator
KLGPHHPM_00672 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
KLGPHHPM_00673 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
KLGPHHPM_00674 1.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KLGPHHPM_00675 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
KLGPHHPM_00676 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
KLGPHHPM_00677 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
KLGPHHPM_00678 1.7e-105 L Helix-turn-helix domain
KLGPHHPM_00679 8.7e-140 L hmm pf00665
KLGPHHPM_00680 1.6e-115 S membrane
KLGPHHPM_00681 8.4e-109 S VIT family
KLGPHHPM_00682 5.5e-83 usp1 T Belongs to the universal stress protein A family
KLGPHHPM_00683 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLGPHHPM_00684 5.7e-152 glnH ET ABC transporter
KLGPHHPM_00685 2.4e-110 gluC P ABC transporter permease
KLGPHHPM_00686 1.4e-108 glnP P ABC transporter permease
KLGPHHPM_00687 8.5e-73 M PFAM NLP P60 protein
KLGPHHPM_00688 2.2e-182 ABC-SBP S ABC transporter
KLGPHHPM_00689 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
KLGPHHPM_00690 1.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
KLGPHHPM_00691 1.2e-92 P Cadmium resistance transporter
KLGPHHPM_00692 6.8e-56 K Transcriptional regulator, ArsR family
KLGPHHPM_00693 4.2e-55 M Leucine-rich repeat (LRR) protein
KLGPHHPM_00694 1.6e-236 mepA V MATE efflux family protein
KLGPHHPM_00695 2.1e-54 trxA O Belongs to the thioredoxin family
KLGPHHPM_00696 2.3e-131 terC P membrane
KLGPHHPM_00697 2.2e-165 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLGPHHPM_00698 4.1e-167 corA P CorA-like Mg2+ transporter protein
KLGPHHPM_00699 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
KLGPHHPM_00700 1.4e-121 fhuC P ABC transporter
KLGPHHPM_00701 1.2e-117 znuB U ABC 3 transport family
KLGPHHPM_00702 2.6e-149 purR 2.4.2.7 F pur operon repressor
KLGPHHPM_00703 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KLGPHHPM_00704 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KLGPHHPM_00705 2.1e-49
KLGPHHPM_00706 2.5e-147 yxeH S hydrolase
KLGPHHPM_00707 5e-270 ywfO S HD domain protein
KLGPHHPM_00708 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
KLGPHHPM_00709 3e-66 ywiB S Domain of unknown function (DUF1934)
KLGPHHPM_00710 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KLGPHHPM_00711 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KLGPHHPM_00712 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLGPHHPM_00713 4.6e-41 rpmE2 J Ribosomal protein L31
KLGPHHPM_00714 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KLGPHHPM_00715 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
KLGPHHPM_00716 5.1e-125 srtA 3.4.22.70 M sortase family
KLGPHHPM_00717 9.5e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
KLGPHHPM_00718 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLGPHHPM_00719 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
KLGPHHPM_00720 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
KLGPHHPM_00721 1.5e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KLGPHHPM_00722 7e-93 lemA S LemA family
KLGPHHPM_00723 2.6e-158 htpX O Belongs to the peptidase M48B family
KLGPHHPM_00724 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KLGPHHPM_00725 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KLGPHHPM_00726 3.1e-126 L PFAM Integrase catalytic region
KLGPHHPM_00727 1e-141 sprD D Domain of Unknown Function (DUF1542)
KLGPHHPM_00728 2.5e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
KLGPHHPM_00729 1.5e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KLGPHHPM_00730 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLGPHHPM_00731 2.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
KLGPHHPM_00732 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KLGPHHPM_00734 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KLGPHHPM_00735 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KLGPHHPM_00736 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
KLGPHHPM_00737 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
KLGPHHPM_00738 4.7e-243 codA 3.5.4.1 F cytosine deaminase
KLGPHHPM_00739 3.1e-147 tesE Q hydratase
KLGPHHPM_00740 4e-113 S (CBS) domain
KLGPHHPM_00741 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KLGPHHPM_00742 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KLGPHHPM_00743 8.1e-39 yabO J S4 domain protein
KLGPHHPM_00744 3.3e-56 divIC D Septum formation initiator
KLGPHHPM_00745 9.8e-67 yabR J RNA binding
KLGPHHPM_00746 3.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KLGPHHPM_00747 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLGPHHPM_00748 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KLGPHHPM_00749 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KLGPHHPM_00750 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KLGPHHPM_00751 6.1e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KLGPHHPM_00752 5.5e-280 O Arylsulfotransferase (ASST)
KLGPHHPM_00753 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KLGPHHPM_00754 1.6e-54 ysxB J Cysteine protease Prp
KLGPHHPM_00755 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
KLGPHHPM_00756 1.8e-110 K Transcriptional regulator
KLGPHHPM_00759 2.5e-89 dut S Protein conserved in bacteria
KLGPHHPM_00760 6.6e-174
KLGPHHPM_00761 1e-151
KLGPHHPM_00762 3.7e-51 S Iron-sulfur cluster assembly protein
KLGPHHPM_00763 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KLGPHHPM_00764 2.2e-154 P Belongs to the nlpA lipoprotein family
KLGPHHPM_00765 3.9e-12
KLGPHHPM_00766 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
KLGPHHPM_00767 3.4e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KLGPHHPM_00768 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
KLGPHHPM_00769 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KLGPHHPM_00770 5.9e-22 S Protein of unknown function (DUF3042)
KLGPHHPM_00771 3.4e-67 yqhL P Rhodanese-like protein
KLGPHHPM_00772 9.6e-183 glk 2.7.1.2 G Glucokinase
KLGPHHPM_00773 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
KLGPHHPM_00774 3.8e-46 gluP 3.4.21.105 S Peptidase, S54 family
KLGPHHPM_00775 3.8e-11 gluP 3.4.21.105 S Peptidase, S54 family
KLGPHHPM_00776 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KLGPHHPM_00777 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLGPHHPM_00778 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
KLGPHHPM_00779 0.0 S membrane
KLGPHHPM_00780 8.8e-71 yneR S Belongs to the HesB IscA family
KLGPHHPM_00781 4.5e-48 L PFAM transposase IS200-family protein
KLGPHHPM_00782 6.5e-165 czcD P cation diffusion facilitator family transporter
KLGPHHPM_00783 2.4e-124 sirR K iron dependent repressor
KLGPHHPM_00784 3.5e-31 cspC K Cold shock protein
KLGPHHPM_00785 3.6e-129 thrE S Putative threonine/serine exporter
KLGPHHPM_00786 6.7e-81 S Threonine/Serine exporter, ThrE
KLGPHHPM_00787 2.7e-120 lssY 3.6.1.27 I phosphatase
KLGPHHPM_00788 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
KLGPHHPM_00789 1.5e-275 lysP E amino acid
KLGPHHPM_00790 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
KLGPHHPM_00796 4.8e-131 S Hydrolases of the alpha beta superfamily
KLGPHHPM_00797 1.3e-16 S Hydrolases of the alpha beta superfamily
KLGPHHPM_00798 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
KLGPHHPM_00799 3.4e-77 ctsR K Belongs to the CtsR family
KLGPHHPM_00800 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KLGPHHPM_00801 1e-110 K Bacterial regulatory proteins, tetR family
KLGPHHPM_00802 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLGPHHPM_00803 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLGPHHPM_00804 1.4e-166 pipD E Dipeptidase
KLGPHHPM_00805 1e-107 L Bacterial dnaA protein
KLGPHHPM_00806 1.4e-09 L Bacterial dnaA protein
KLGPHHPM_00807 1e-116 L Integrase core domain
KLGPHHPM_00808 2.9e-99 L Integrase core domain
KLGPHHPM_00810 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KLGPHHPM_00811 4e-56 K transcriptional regulator PadR family
KLGPHHPM_00812 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
KLGPHHPM_00813 6.4e-126 S Putative adhesin
KLGPHHPM_00814 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KLGPHHPM_00815 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLGPHHPM_00816 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KLGPHHPM_00817 3.4e-35 nrdH O Glutaredoxin
KLGPHHPM_00818 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KLGPHHPM_00819 6.2e-292 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KLGPHHPM_00820 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KLGPHHPM_00821 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KLGPHHPM_00822 9.7e-39 S Protein of unknown function (DUF2508)
KLGPHHPM_00823 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KLGPHHPM_00824 7.6e-52 yaaQ S Cyclic-di-AMP receptor
KLGPHHPM_00825 2.8e-185 holB 2.7.7.7 L DNA polymerase III
KLGPHHPM_00826 5.9e-58 yabA L Involved in initiation control of chromosome replication
KLGPHHPM_00827 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KLGPHHPM_00828 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
KLGPHHPM_00829 3.2e-278 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLGPHHPM_00830 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KLGPHHPM_00831 1.8e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLGPHHPM_00832 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KLGPHHPM_00833 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
KLGPHHPM_00834 7.9e-35 copZ C Heavy-metal-associated domain
KLGPHHPM_00835 6.7e-93 dps P Belongs to the Dps family
KLGPHHPM_00836 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
KLGPHHPM_00837 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KLGPHHPM_00838 5.8e-184 S Phosphotransferase system, EIIC
KLGPHHPM_00839 4.1e-22 L PFAM Integrase catalytic region
KLGPHHPM_00840 0.0 M domain protein
KLGPHHPM_00841 4.5e-91
KLGPHHPM_00843 1.9e-159 yjcE P Sodium proton antiporter
KLGPHHPM_00844 1e-73 yjcE P Sodium proton antiporter
KLGPHHPM_00846 5.2e-56
KLGPHHPM_00848 4.5e-85
KLGPHHPM_00849 0.0 copA 3.6.3.54 P P-type ATPase
KLGPHHPM_00850 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KLGPHHPM_00851 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
KLGPHHPM_00852 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KLGPHHPM_00853 3.3e-161 EG EamA-like transporter family
KLGPHHPM_00854 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
KLGPHHPM_00855 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KLGPHHPM_00856 8.1e-154 KT YcbB domain
KLGPHHPM_00857 6.7e-300 xylB 2.7.1.17 G Belongs to the FGGY kinase family
KLGPHHPM_00858 5.6e-164 xylR GK ROK family
KLGPHHPM_00859 1.3e-28
KLGPHHPM_00860 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
KLGPHHPM_00861 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
KLGPHHPM_00862 2.6e-155 glcU U sugar transport
KLGPHHPM_00863 6.8e-273 yclK 2.7.13.3 T Histidine kinase
KLGPHHPM_00864 1.5e-132 K response regulator
KLGPHHPM_00866 2.8e-79 lytE M Lysin motif
KLGPHHPM_00867 2e-149 XK27_02985 S Cof-like hydrolase
KLGPHHPM_00868 6.6e-81 K Transcriptional regulator
KLGPHHPM_00869 0.0 oatA I Acyltransferase
KLGPHHPM_00870 8.7e-53
KLGPHHPM_00871 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KLGPHHPM_00872 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KLGPHHPM_00873 2e-126 ybbR S YbbR-like protein
KLGPHHPM_00874 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KLGPHHPM_00875 6.1e-244 fucP G Major Facilitator Superfamily
KLGPHHPM_00876 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KLGPHHPM_00877 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KLGPHHPM_00878 3.6e-168 murB 1.3.1.98 M Cell wall formation
KLGPHHPM_00879 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
KLGPHHPM_00880 4.4e-76 S PAS domain
KLGPHHPM_00881 2.6e-86 K Acetyltransferase (GNAT) domain
KLGPHHPM_00882 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
KLGPHHPM_00883 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KLGPHHPM_00884 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KLGPHHPM_00885 6.3e-105 yxjI
KLGPHHPM_00886 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KLGPHHPM_00887 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KLGPHHPM_00888 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
KLGPHHPM_00889 1.8e-34 secG U Preprotein translocase
KLGPHHPM_00890 2.6e-291 clcA P chloride
KLGPHHPM_00891 7.1e-248 yifK E Amino acid permease
KLGPHHPM_00892 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KLGPHHPM_00893 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLGPHHPM_00894 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KLGPHHPM_00895 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KLGPHHPM_00897 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KLGPHHPM_00898 8.8e-15
KLGPHHPM_00900 4e-170 whiA K May be required for sporulation
KLGPHHPM_00901 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KLGPHHPM_00902 1.1e-161 rapZ S Displays ATPase and GTPase activities
KLGPHHPM_00903 5.4e-245 steT E amino acid
KLGPHHPM_00904 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KLGPHHPM_00905 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KLGPHHPM_00906 1.5e-13
KLGPHHPM_00907 2.3e-116 yfbR S HD containing hydrolase-like enzyme
KLGPHHPM_00908 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
KLGPHHPM_00909 1.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
KLGPHHPM_00910 1.3e-157 aatB ET PFAM extracellular solute-binding protein, family 3
KLGPHHPM_00911 2.5e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KLGPHHPM_00912 1.5e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KLGPHHPM_00913 3.9e-162 lutA C Cysteine-rich domain
KLGPHHPM_00914 7.5e-288 lutB C 4Fe-4S dicluster domain
KLGPHHPM_00915 3.9e-136 yrjD S LUD domain
KLGPHHPM_00916 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KLGPHHPM_00917 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KLGPHHPM_00918 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KLGPHHPM_00919 1.7e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KLGPHHPM_00920 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KLGPHHPM_00921 3.1e-32 KT PspC domain protein
KLGPHHPM_00922 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KLGPHHPM_00923 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KLGPHHPM_00924 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KLGPHHPM_00925 1.3e-114 comFC S Competence protein
KLGPHHPM_00926 1.4e-256 comFA L Helicase C-terminal domain protein
KLGPHHPM_00927 2.9e-111 yvyE 3.4.13.9 S YigZ family
KLGPHHPM_00928 4e-235 EGP Major facilitator Superfamily
KLGPHHPM_00929 7.4e-68 rmaI K Transcriptional regulator
KLGPHHPM_00930 9.2e-40
KLGPHHPM_00931 0.0 ydaO E amino acid
KLGPHHPM_00932 7.3e-305 ybeC E amino acid
KLGPHHPM_00933 1.1e-81 S YbaK proline--tRNA ligase associated domain protein
KLGPHHPM_00934 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KLGPHHPM_00935 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KLGPHHPM_00937 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KLGPHHPM_00938 6.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KLGPHHPM_00939 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
KLGPHHPM_00940 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KLGPHHPM_00941 6.9e-103 metI P ABC transporter permease
KLGPHHPM_00942 7e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
KLGPHHPM_00943 1.2e-252 clcA P chloride
KLGPHHPM_00944 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KLGPHHPM_00945 4.5e-104 proW P ABC transporter, permease protein
KLGPHHPM_00946 1e-139 proV E ABC transporter, ATP-binding protein
KLGPHHPM_00947 6.3e-109 proWZ P ABC transporter permease
KLGPHHPM_00948 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
KLGPHHPM_00949 9e-75 K Transcriptional regulator
KLGPHHPM_00950 4.8e-154 1.6.5.2 GM NAD(P)H-binding
KLGPHHPM_00952 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
KLGPHHPM_00953 0.0 cadA P P-type ATPase
KLGPHHPM_00954 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
KLGPHHPM_00955 2.1e-126
KLGPHHPM_00956 3.3e-55 S Sugar efflux transporter for intercellular exchange
KLGPHHPM_00957 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
KLGPHHPM_00959 0.0 L Helicase C-terminal domain protein
KLGPHHPM_00960 1.2e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
KLGPHHPM_00961 5.9e-177 S Aldo keto reductase
KLGPHHPM_00963 1.1e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KLGPHHPM_00964 4.5e-62 psiE S Phosphate-starvation-inducible E
KLGPHHPM_00965 2.1e-102 ydeN S Serine hydrolase
KLGPHHPM_00967 1.3e-182 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KLGPHHPM_00968 7.2e-256 nhaC C Na H antiporter NhaC
KLGPHHPM_00969 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
KLGPHHPM_00970 4.8e-114 ywnB S NAD(P)H-binding
KLGPHHPM_00971 2.9e-37
KLGPHHPM_00972 6.8e-121 radC L DNA repair protein
KLGPHHPM_00973 1.7e-179 mreB D cell shape determining protein MreB
KLGPHHPM_00974 8.5e-151 mreC M Involved in formation and maintenance of cell shape
KLGPHHPM_00975 1.2e-91 mreD M rod shape-determining protein MreD
KLGPHHPM_00976 9.4e-102 glnP P ABC transporter permease
KLGPHHPM_00977 1.8e-116 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLGPHHPM_00978 2.6e-160 aatB ET ABC transporter substrate-binding protein
KLGPHHPM_00979 1.3e-229 ymfF S Peptidase M16 inactive domain protein
KLGPHHPM_00980 9.3e-250 ymfH S Peptidase M16
KLGPHHPM_00981 7.4e-141 ymfM S Helix-turn-helix domain
KLGPHHPM_00982 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KLGPHHPM_00983 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
KLGPHHPM_00984 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KLGPHHPM_00985 6.2e-20 cotH M CotH kinase protein
KLGPHHPM_00986 6.5e-34
KLGPHHPM_00987 5e-73 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KLGPHHPM_00988 9.4e-180 M Glycosyl hydrolases family 25
KLGPHHPM_00989 1.1e-54 V Abi-like protein
KLGPHHPM_00990 1.9e-206 L Belongs to the 'phage' integrase family
KLGPHHPM_00991 1e-48
KLGPHHPM_00994 1.2e-13 L nuclease
KLGPHHPM_00995 4.2e-70 3.4.21.88 K Peptidase S24-like
KLGPHHPM_00996 1.7e-09 K Helix-turn-helix XRE-family like proteins
KLGPHHPM_01003 9.2e-159 recT L RecT family
KLGPHHPM_01004 7.6e-157 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
KLGPHHPM_01005 2.7e-48 L Psort location Cytoplasmic, score
KLGPHHPM_01006 2.9e-54
KLGPHHPM_01010 5.7e-21
KLGPHHPM_01016 3.9e-34
KLGPHHPM_01017 1.5e-82
KLGPHHPM_01018 6.4e-07
KLGPHHPM_01020 5.7e-22
KLGPHHPM_01021 6.7e-139 S Pfam:Terminase_3C
KLGPHHPM_01022 3.6e-23 L HNH endonuclease
KLGPHHPM_01023 2.2e-133 S Phage portal protein, SPP1 Gp6-like
KLGPHHPM_01024 4.6e-91 S Phage minor capsid protein 2
KLGPHHPM_01025 3e-19 S Phage minor structural protein GP20
KLGPHHPM_01026 4.8e-101
KLGPHHPM_01027 9.2e-13
KLGPHHPM_01028 1.8e-30 S Minor capsid protein
KLGPHHPM_01029 4.2e-13 S Minor capsid protein
KLGPHHPM_01030 4.2e-15 S Minor capsid protein from bacteriophage
KLGPHHPM_01031 4.3e-39 N domain, Protein
KLGPHHPM_01033 3.5e-37 S Bacteriophage Gp15 protein
KLGPHHPM_01034 7.9e-115 S peptidoglycan catabolic process
KLGPHHPM_01035 4.1e-70 S Phage tail protein
KLGPHHPM_01036 3.1e-61 M Prophage endopeptidase tail
KLGPHHPM_01039 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KLGPHHPM_01040 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KLGPHHPM_01041 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KLGPHHPM_01042 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KLGPHHPM_01043 4.5e-49 ylxQ J ribosomal protein
KLGPHHPM_01044 1e-44 ylxR K Protein of unknown function (DUF448)
KLGPHHPM_01045 6.8e-215 nusA K Participates in both transcription termination and antitermination
KLGPHHPM_01046 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
KLGPHHPM_01048 1.5e-200 3.5.1.104 M hydrolase, family 25
KLGPHHPM_01049 6.8e-64 S Bacteriophage holin of superfamily 6 (Holin_LLH)
KLGPHHPM_01050 5.3e-15
KLGPHHPM_01051 0.0 cotH M CotH kinase protein
KLGPHHPM_01054 1.7e-85 3.4.24.40 M Peptidase family M23
KLGPHHPM_01055 3.3e-36
KLGPHHPM_01056 3.5e-295 M Prophage endopeptidase tail
KLGPHHPM_01057 1.1e-139 S Phage tail protein
KLGPHHPM_01058 1.9e-214 M Phage tail tape measure protein TP901
KLGPHHPM_01060 1.4e-18
KLGPHHPM_01061 3.1e-66 S Phage tail tube protein
KLGPHHPM_01062 2.2e-24
KLGPHHPM_01063 5.7e-21
KLGPHHPM_01064 2.6e-37 S Phage head-tail joining protein
KLGPHHPM_01065 1.7e-44 S Phage gp6-like head-tail connector protein
KLGPHHPM_01066 1.5e-131 S Phage capsid family
KLGPHHPM_01067 2.3e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
KLGPHHPM_01068 5.7e-146 S portal protein
KLGPHHPM_01069 2.1e-276 S Phage Terminase
KLGPHHPM_01070 1.1e-75 L Phage terminase, small subunit
KLGPHHPM_01071 4.2e-53 L HNH nucleases
KLGPHHPM_01083 1.2e-48
KLGPHHPM_01084 2.4e-24 E Zn peptidase
KLGPHHPM_01085 2.7e-38 S HicB_like antitoxin of bacterial toxin-antitoxin system
KLGPHHPM_01091 1.3e-131 pnuC H nicotinamide mononucleotide transporter
KLGPHHPM_01106 4.3e-207 XK27_11280 S Psort location CytoplasmicMembrane, score
KLGPHHPM_01107 6.6e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KLGPHHPM_01108 6.4e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
KLGPHHPM_01109 3e-238 S polysaccharide biosynthetic process
KLGPHHPM_01110 2e-233 S Psort location CytoplasmicMembrane, score 9.99
KLGPHHPM_01111 3.7e-182 M Glycosyl transferase, family 2
KLGPHHPM_01112 5.4e-181 GT2 M Glycosyltransferase like family 2
KLGPHHPM_01113 4e-184 M family 8
KLGPHHPM_01114 2e-194 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLGPHHPM_01115 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KLGPHHPM_01116 3.7e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KLGPHHPM_01117 7.5e-115 rfbP M Bacterial sugar transferase
KLGPHHPM_01118 8.5e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
KLGPHHPM_01119 3.8e-146 epsB M biosynthesis protein
KLGPHHPM_01120 9e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KLGPHHPM_01121 2.3e-66 K Transcriptional regulator, HxlR family
KLGPHHPM_01122 6.1e-91
KLGPHHPM_01123 7.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
KLGPHHPM_01124 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KLGPHHPM_01125 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
KLGPHHPM_01126 4.7e-114 yjbH Q Thioredoxin
KLGPHHPM_01127 5.9e-114 L PFAM Integrase catalytic region
KLGPHHPM_01128 2.5e-158 L hmm pf00665
KLGPHHPM_01129 4.4e-100 L Helix-turn-helix domain
KLGPHHPM_01131 5.9e-191 V Beta-lactamase
KLGPHHPM_01132 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KLGPHHPM_01133 1.1e-121 yhiD S MgtC family
KLGPHHPM_01134 6.4e-39 S GyrI-like small molecule binding domain
KLGPHHPM_01135 2.7e-70 S GyrI-like small molecule binding domain
KLGPHHPM_01137 6.1e-117 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
KLGPHHPM_01138 7.1e-50 azlD E Branched-chain amino acid transport
KLGPHHPM_01139 7.5e-83 azlC E azaleucine resistance protein AzlC
KLGPHHPM_01140 2.1e-260 K Aminotransferase class I and II
KLGPHHPM_01141 3.6e-288 S amidohydrolase
KLGPHHPM_01143 1.8e-161 S reductase
KLGPHHPM_01144 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
KLGPHHPM_01145 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KLGPHHPM_01146 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
KLGPHHPM_01147 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KLGPHHPM_01148 0.0 asnB 6.3.5.4 E Asparagine synthase
KLGPHHPM_01149 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KLGPHHPM_01150 1.3e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KLGPHHPM_01151 9.7e-130 jag S R3H domain protein
KLGPHHPM_01152 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLGPHHPM_01153 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KLGPHHPM_01154 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KLGPHHPM_01155 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KLGPHHPM_01156 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KLGPHHPM_01157 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
KLGPHHPM_01158 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
KLGPHHPM_01159 1.7e-34 yaaA S S4 domain protein YaaA
KLGPHHPM_01160 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KLGPHHPM_01161 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLGPHHPM_01162 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KLGPHHPM_01163 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KLGPHHPM_01164 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLGPHHPM_01165 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KLGPHHPM_01166 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KLGPHHPM_01167 2e-74 rplI J Binds to the 23S rRNA
KLGPHHPM_01168 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KLGPHHPM_01169 9.9e-206 yttB EGP Major facilitator Superfamily
KLGPHHPM_01170 3.7e-54
KLGPHHPM_01171 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
KLGPHHPM_01172 9.8e-09 K DNA-binding helix-turn-helix protein
KLGPHHPM_01173 2.3e-78 O Bacterial dnaA protein
KLGPHHPM_01174 2.5e-158 L hmm pf00665
KLGPHHPM_01175 4.4e-100 L Helix-turn-helix domain
KLGPHHPM_01177 3.1e-226 yxiO S Vacuole effluxer Atg22 like
KLGPHHPM_01178 9.7e-216 npp S type I phosphodiesterase nucleotide pyrophosphatase
KLGPHHPM_01179 1.1e-240 E amino acid
KLGPHHPM_01180 6.7e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLGPHHPM_01182 6.7e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
KLGPHHPM_01183 7.8e-41 S Cytochrome B5
KLGPHHPM_01184 5.4e-09 S Cytochrome B5
KLGPHHPM_01185 1.8e-39 S Cytochrome B5
KLGPHHPM_01186 1.7e-70 elaA S Gnat family
KLGPHHPM_01187 3e-119 GM NmrA-like family
KLGPHHPM_01188 2.5e-52 hxlR K Transcriptional regulator, HxlR family
KLGPHHPM_01189 3.7e-108 XK27_02070 S Nitroreductase family
KLGPHHPM_01190 7.8e-79 K Transcriptional regulator, HxlR family
KLGPHHPM_01191 1.6e-228
KLGPHHPM_01192 6.5e-210 EGP Major facilitator Superfamily
KLGPHHPM_01193 4.8e-254 pepC 3.4.22.40 E aminopeptidase
KLGPHHPM_01194 5.8e-112 ylbE GM NAD dependent epimerase dehydratase family protein
KLGPHHPM_01195 0.0 pepN 3.4.11.2 E aminopeptidase
KLGPHHPM_01196 2e-92 folT S ECF transporter, substrate-specific component
KLGPHHPM_01197 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
KLGPHHPM_01198 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
KLGPHHPM_01199 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
KLGPHHPM_01200 1.2e-203 2.7.7.65 T GGDEF domain
KLGPHHPM_01201 5.2e-84
KLGPHHPM_01202 1e-251 pgaC GT2 M Glycosyl transferase
KLGPHHPM_01203 3.7e-140 T EAL domain
KLGPHHPM_01204 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
KLGPHHPM_01205 1.1e-64 yneR
KLGPHHPM_01206 1.2e-112 GM NAD(P)H-binding
KLGPHHPM_01207 6.1e-88 S membrane
KLGPHHPM_01208 1e-73 S membrane
KLGPHHPM_01209 1.8e-104 K Transcriptional regulator C-terminal region
KLGPHHPM_01210 3.2e-118 akr5f 1.1.1.346 S reductase
KLGPHHPM_01211 6.5e-28 akr5f 1.1.1.346 S reductase
KLGPHHPM_01212 4.3e-40 K Transcriptional regulator
KLGPHHPM_01213 4.3e-59 K Transcriptional regulator
KLGPHHPM_01214 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
KLGPHHPM_01215 2.3e-155 ypuA S Protein of unknown function (DUF1002)
KLGPHHPM_01216 4.7e-66 GM NAD(P)H-binding
KLGPHHPM_01217 3.3e-92 padR K Virulence activator alpha C-term
KLGPHHPM_01218 2.3e-93 padC Q Phenolic acid decarboxylase
KLGPHHPM_01219 2e-152 S Alpha beta hydrolase
KLGPHHPM_01220 9.4e-32 S thiolester hydrolase activity
KLGPHHPM_01221 6.3e-88 lacA S transferase hexapeptide repeat
KLGPHHPM_01222 5.6e-158 K Transcriptional regulator
KLGPHHPM_01223 2.7e-85 C Flavodoxin
KLGPHHPM_01224 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
KLGPHHPM_01225 1.7e-163 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
KLGPHHPM_01227 3.4e-250 mmuP E amino acid
KLGPHHPM_01228 5.2e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
KLGPHHPM_01229 3.8e-44
KLGPHHPM_01231 1.8e-09
KLGPHHPM_01232 1.7e-70 pipD E Dipeptidase
KLGPHHPM_01233 1.6e-241 pbuX F xanthine permease
KLGPHHPM_01234 4.1e-251 nhaC C Na H antiporter NhaC
KLGPHHPM_01235 1.4e-284 S C4-dicarboxylate anaerobic carrier
KLGPHHPM_01236 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
KLGPHHPM_01237 3.8e-41
KLGPHHPM_01238 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLGPHHPM_01239 1.7e-207 gldA 1.1.1.6 C dehydrogenase
KLGPHHPM_01240 7.5e-123 S Alpha beta hydrolase
KLGPHHPM_01241 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLGPHHPM_01242 2.1e-100
KLGPHHPM_01244 1.4e-124 yciB M ErfK YbiS YcfS YnhG
KLGPHHPM_01245 2.8e-162 yueF S AI-2E family transporter
KLGPHHPM_01246 9.2e-230 brpA K Cell envelope-like function transcriptional attenuator common domain protein
KLGPHHPM_01247 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KLGPHHPM_01248 2.2e-34 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
KLGPHHPM_01249 5e-241 M NlpC/P60 family
KLGPHHPM_01250 3.1e-245 M NlpC/P60 family
KLGPHHPM_01251 0.0 sbcC L Putative exonuclease SbcCD, C subunit
KLGPHHPM_01252 2.2e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KLGPHHPM_01253 1.4e-170 M Glycosyl hydrolases family 25
KLGPHHPM_01254 4.5e-143 ywqE 3.1.3.48 GM PHP domain protein
KLGPHHPM_01255 0.0 snf 2.7.11.1 KL domain protein
KLGPHHPM_01257 8.9e-37
KLGPHHPM_01258 1.9e-34 T Toxin-antitoxin system, toxin component, MazF family
KLGPHHPM_01259 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
KLGPHHPM_01260 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KLGPHHPM_01261 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KLGPHHPM_01262 2.2e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLGPHHPM_01263 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLGPHHPM_01264 8.8e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KLGPHHPM_01265 1.1e-62 rplQ J Ribosomal protein L17
KLGPHHPM_01266 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KLGPHHPM_01267 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KLGPHHPM_01268 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KLGPHHPM_01269 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KLGPHHPM_01270 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KLGPHHPM_01271 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KLGPHHPM_01272 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KLGPHHPM_01273 8.9e-64 rplO J Binds to the 23S rRNA
KLGPHHPM_01274 2.9e-24 rpmD J Ribosomal protein L30
KLGPHHPM_01275 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KLGPHHPM_01276 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KLGPHHPM_01277 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KLGPHHPM_01278 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KLGPHHPM_01279 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLGPHHPM_01280 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KLGPHHPM_01281 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KLGPHHPM_01282 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KLGPHHPM_01283 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KLGPHHPM_01284 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
KLGPHHPM_01285 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KLGPHHPM_01286 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KLGPHHPM_01287 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KLGPHHPM_01288 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KLGPHHPM_01289 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KLGPHHPM_01290 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KLGPHHPM_01291 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
KLGPHHPM_01292 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KLGPHHPM_01293 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KLGPHHPM_01301 1.7e-09
KLGPHHPM_01302 5.8e-18 K Cro/C1-type HTH DNA-binding domain
KLGPHHPM_01304 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
KLGPHHPM_01305 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KLGPHHPM_01306 6e-123 O Zinc-dependent metalloprotease
KLGPHHPM_01307 1.4e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
KLGPHHPM_01308 1.5e-180 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KLGPHHPM_01309 3.5e-186 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KLGPHHPM_01310 9.7e-93 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
KLGPHHPM_01311 2.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
KLGPHHPM_01312 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KLGPHHPM_01313 8.1e-102 T Ion transport 2 domain protein
KLGPHHPM_01314 0.0 S Bacterial membrane protein YfhO
KLGPHHPM_01315 5e-202 G Transporter, major facilitator family protein
KLGPHHPM_01316 2.4e-109 yvrI K sigma factor activity
KLGPHHPM_01317 3.5e-64 ydiI Q Thioesterase superfamily
KLGPHHPM_01318 7e-27 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KLGPHHPM_01319 6.4e-122 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KLGPHHPM_01320 4.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KLGPHHPM_01321 5.5e-19
KLGPHHPM_01322 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
KLGPHHPM_01323 4.2e-32 feoA P FeoA domain
KLGPHHPM_01324 6.5e-145 sufC O FeS assembly ATPase SufC
KLGPHHPM_01325 1.2e-236 sufD O FeS assembly protein SufD
KLGPHHPM_01326 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KLGPHHPM_01327 1.9e-80 nifU C SUF system FeS assembly protein, NifU family
KLGPHHPM_01328 1.6e-271 sufB O assembly protein SufB
KLGPHHPM_01329 2.8e-57 yitW S Iron-sulfur cluster assembly protein
KLGPHHPM_01330 6.1e-160 hipB K Helix-turn-helix
KLGPHHPM_01331 9.8e-115 nreC K PFAM regulatory protein LuxR
KLGPHHPM_01332 9.2e-39 S Cytochrome B5
KLGPHHPM_01333 6.4e-156 yitU 3.1.3.104 S hydrolase
KLGPHHPM_01334 1.5e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
KLGPHHPM_01335 4e-148 f42a O Band 7 protein
KLGPHHPM_01336 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
KLGPHHPM_01337 2.4e-130 lytT K response regulator receiver
KLGPHHPM_01338 1.9e-66 lrgA S LrgA family
KLGPHHPM_01339 2.6e-124 lrgB M LrgB-like family
KLGPHHPM_01340 1.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLGPHHPM_01341 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
KLGPHHPM_01342 1.2e-188 galR K Periplasmic binding protein-like domain
KLGPHHPM_01343 0.0 rafA 3.2.1.22 G alpha-galactosidase
KLGPHHPM_01344 3.8e-87 S Protein of unknown function (DUF1440)
KLGPHHPM_01345 1.9e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KLGPHHPM_01346 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
KLGPHHPM_01347 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
KLGPHHPM_01348 5.7e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
KLGPHHPM_01349 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KLGPHHPM_01350 2.9e-85 ypmB S Protein conserved in bacteria
KLGPHHPM_01351 3e-125 dnaD L DnaD domain protein
KLGPHHPM_01352 2e-161 EG EamA-like transporter family
KLGPHHPM_01353 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
KLGPHHPM_01354 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KLGPHHPM_01355 2.8e-105 ypsA S Belongs to the UPF0398 family
KLGPHHPM_01356 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KLGPHHPM_01357 3.8e-66 yqkB S Belongs to the HesB IscA family
KLGPHHPM_01358 2.7e-49
KLGPHHPM_01360 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
KLGPHHPM_01361 1.3e-61 asp S Asp23 family, cell envelope-related function
KLGPHHPM_01362 2.1e-25
KLGPHHPM_01363 8e-94
KLGPHHPM_01364 1.6e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLGPHHPM_01365 9.9e-183 K Transcriptional regulator, LacI family
KLGPHHPM_01366 1.3e-225 gntT EG Gluconate
KLGPHHPM_01367 2.2e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
KLGPHHPM_01368 2.9e-96 K Acetyltransferase (GNAT) domain
KLGPHHPM_01369 5.4e-47
KLGPHHPM_01370 2.4e-22
KLGPHHPM_01371 2.2e-44
KLGPHHPM_01372 5.4e-57 yhaI S Protein of unknown function (DUF805)
KLGPHHPM_01373 2.6e-106 L Uncharacterized conserved protein (DUF2075)
KLGPHHPM_01374 0.0 L PLD-like domain
KLGPHHPM_01376 5e-75 osmC O OsmC-like protein
KLGPHHPM_01377 1.2e-175 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLGPHHPM_01378 6.1e-216 patA 2.6.1.1 E Aminotransferase
KLGPHHPM_01379 7.8e-32
KLGPHHPM_01380 0.0 clpL O associated with various cellular activities
KLGPHHPM_01382 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
KLGPHHPM_01383 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLGPHHPM_01384 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
KLGPHHPM_01385 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KLGPHHPM_01386 1.5e-172 malR K Transcriptional regulator, LacI family
KLGPHHPM_01387 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
KLGPHHPM_01388 1.3e-226 aadAT EK Aminotransferase, class I
KLGPHHPM_01389 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KLGPHHPM_01390 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KLGPHHPM_01391 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
KLGPHHPM_01392 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KLGPHHPM_01393 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KLGPHHPM_01394 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLGPHHPM_01395 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KLGPHHPM_01396 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLGPHHPM_01397 1.7e-207 yacL S domain protein
KLGPHHPM_01398 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KLGPHHPM_01399 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
KLGPHHPM_01400 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
KLGPHHPM_01401 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KLGPHHPM_01402 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
KLGPHHPM_01403 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KLGPHHPM_01404 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLGPHHPM_01405 2.4e-119 tcyB E ABC transporter
KLGPHHPM_01406 4.2e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KLGPHHPM_01407 3.1e-169 I alpha/beta hydrolase fold
KLGPHHPM_01408 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KLGPHHPM_01409 0.0 S Bacterial membrane protein, YfhO
KLGPHHPM_01410 1.3e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
KLGPHHPM_01411 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
KLGPHHPM_01414 2.7e-24
KLGPHHPM_01415 1e-51
KLGPHHPM_01416 4e-182 M LPXTG-motif cell wall anchor domain protein
KLGPHHPM_01417 0.0 M LPXTG-motif cell wall anchor domain protein
KLGPHHPM_01418 1.1e-19 M LPXTG-motif cell wall anchor domain protein
KLGPHHPM_01420 0.0
KLGPHHPM_01422 4.2e-74 S Transcriptional regulator, RinA family
KLGPHHPM_01427 7.4e-79 S nucleoside kinase activity
KLGPHHPM_01433 3.9e-139
KLGPHHPM_01437 3.3e-80 Q DNA (cytosine-5-)-methyltransferase activity
KLGPHHPM_01446 1.6e-76 rusA L Endodeoxyribonuclease RusA
KLGPHHPM_01447 3.9e-30
KLGPHHPM_01448 2.6e-23
KLGPHHPM_01456 5.4e-94 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KLGPHHPM_01459 4.9e-133 L Psort location Cytoplasmic, score
KLGPHHPM_01460 1.1e-129 S Putative HNHc nuclease
KLGPHHPM_01461 5.4e-57 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KLGPHHPM_01466 5.4e-08
KLGPHHPM_01468 1.1e-109 S Protein of unknown function (DUF3102)
KLGPHHPM_01469 1.6e-18
KLGPHHPM_01470 6e-57 K addiction module antidote protein HigA
KLGPHHPM_01471 1.3e-73 E IrrE N-terminal-like domain
KLGPHHPM_01474 6.1e-59 L Belongs to the 'phage' integrase family
KLGPHHPM_01477 1.3e-260 S Putative peptidoglycan binding domain
KLGPHHPM_01478 4e-28 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KLGPHHPM_01479 7.9e-188 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
KLGPHHPM_01480 2e-53
KLGPHHPM_01481 1.1e-113 frnE Q DSBA-like thioredoxin domain
KLGPHHPM_01482 1.7e-78 I alpha/beta hydrolase fold
KLGPHHPM_01483 8.5e-20 K Helix-turn-helix XRE-family like proteins
KLGPHHPM_01484 1.1e-35 S Phage derived protein Gp49-like (DUF891)
KLGPHHPM_01486 1.6e-45 yrvD S Pfam:DUF1049
KLGPHHPM_01487 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
KLGPHHPM_01488 8.1e-90 ntd 2.4.2.6 F Nucleoside
KLGPHHPM_01489 1.3e-20
KLGPHHPM_01490 4e-164 S Alpha/beta hydrolase of unknown function (DUF915)
KLGPHHPM_01491 6.2e-114 yviA S Protein of unknown function (DUF421)
KLGPHHPM_01492 3.1e-72 S Protein of unknown function (DUF3290)
KLGPHHPM_01493 6.2e-41 ybaN S Protein of unknown function (DUF454)
KLGPHHPM_01495 1.9e-225 L Transposase IS66 family
KLGPHHPM_01497 6.8e-22 K Helix-turn-helix domain
KLGPHHPM_01498 9.3e-21 D nuclear chromosome segregation
KLGPHHPM_01502 2e-62 repB EP Plasmid replication protein
KLGPHHPM_01503 5.5e-16
KLGPHHPM_01504 1.1e-130 L Belongs to the 'phage' integrase family
KLGPHHPM_01505 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KLGPHHPM_01506 2.4e-65 K HxlR-like helix-turn-helix
KLGPHHPM_01507 8.5e-54 S macrophage migration inhibitory factor
KLGPHHPM_01508 1.1e-50 yqiG C Oxidoreductase
KLGPHHPM_01509 7.8e-20 yqiG C Oxidoreductase
KLGPHHPM_01510 3.7e-91 yqiG C Oxidoreductase
KLGPHHPM_01512 3.7e-19
KLGPHHPM_01513 5e-263 dtpT U amino acid peptide transporter
KLGPHHPM_01514 1.4e-158 yjjH S Calcineurin-like phosphoesterase
KLGPHHPM_01517 5.5e-110
KLGPHHPM_01518 2.8e-252 EGP Major facilitator Superfamily
KLGPHHPM_01519 9.5e-300 aspT P Predicted Permease Membrane Region
KLGPHHPM_01520 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KLGPHHPM_01521 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
KLGPHHPM_01522 1.7e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KLGPHHPM_01523 5.1e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KLGPHHPM_01524 0.0 yhgF K Tex-like protein N-terminal domain protein
KLGPHHPM_01525 1.9e-85 ydcK S Belongs to the SprT family
KLGPHHPM_01527 6.7e-56 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KLGPHHPM_01528 2.7e-48 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KLGPHHPM_01529 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLGPHHPM_01530 3.6e-310 lmrA V ABC transporter, ATP-binding protein
KLGPHHPM_01531 0.0 yfiC V ABC transporter
KLGPHHPM_01532 1.1e-283 pipD E Dipeptidase
KLGPHHPM_01533 3.9e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KLGPHHPM_01534 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
KLGPHHPM_01535 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
KLGPHHPM_01536 2.7e-244 yagE E amino acid
KLGPHHPM_01537 6.5e-139 aroD S Serine hydrolase (FSH1)
KLGPHHPM_01538 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
KLGPHHPM_01539 5.2e-167 GK ROK family
KLGPHHPM_01540 0.0 tetP J elongation factor G
KLGPHHPM_01541 5.1e-81 uspA T universal stress protein
KLGPHHPM_01542 3.3e-194 lplA 6.3.1.20 H Lipoate-protein ligase
KLGPHHPM_01543 7.1e-63
KLGPHHPM_01544 5.2e-14
KLGPHHPM_01545 2.8e-107
KLGPHHPM_01546 8.8e-135 V ABC transporter
KLGPHHPM_01547 2.4e-212 EGP Major facilitator Superfamily
KLGPHHPM_01548 1.3e-257 G PTS system Galactitol-specific IIC component
KLGPHHPM_01549 1.3e-179 1.6.5.5 C Zinc-binding dehydrogenase
KLGPHHPM_01550 1.1e-161
KLGPHHPM_01551 1e-72 K Transcriptional regulator
KLGPHHPM_01552 3.7e-190 D Alpha beta
KLGPHHPM_01553 2.2e-52 ypaA S Protein of unknown function (DUF1304)
KLGPHHPM_01554 0.0 yjcE P Sodium proton antiporter
KLGPHHPM_01555 1.6e-52 yvlA
KLGPHHPM_01556 2.1e-106 P Cobalt transport protein
KLGPHHPM_01557 1e-246 cbiO1 S ABC transporter, ATP-binding protein
KLGPHHPM_01558 3e-96 S ABC-type cobalt transport system, permease component
KLGPHHPM_01559 3.3e-133 S membrane transporter protein
KLGPHHPM_01560 4.6e-117 IQ KR domain
KLGPHHPM_01561 1.3e-08 IQ KR domain
KLGPHHPM_01562 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
KLGPHHPM_01563 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
KLGPHHPM_01564 3.3e-149 L hmm pf00665
KLGPHHPM_01565 2.5e-127 L Helix-turn-helix domain
KLGPHHPM_01566 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLGPHHPM_01567 3.2e-138 csd1 3.5.1.28 G domain, Protein
KLGPHHPM_01568 3e-133 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KLGPHHPM_01569 2.7e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
KLGPHHPM_01570 3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KLGPHHPM_01571 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KLGPHHPM_01572 6.8e-37 veg S Biofilm formation stimulator VEG
KLGPHHPM_01573 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KLGPHHPM_01574 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KLGPHHPM_01575 1.9e-155 tatD L hydrolase, TatD family
KLGPHHPM_01576 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KLGPHHPM_01577 3.6e-162 yunF F Protein of unknown function DUF72
KLGPHHPM_01579 3e-130 cobB K SIR2 family
KLGPHHPM_01580 1.6e-177
KLGPHHPM_01581 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
KLGPHHPM_01582 1.3e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
KLGPHHPM_01583 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLGPHHPM_01584 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KLGPHHPM_01585 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
KLGPHHPM_01586 0.0 helD 3.6.4.12 L DNA helicase
KLGPHHPM_01587 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KLGPHHPM_01589 2e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KLGPHHPM_01590 1e-265 yfnA E amino acid
KLGPHHPM_01591 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KLGPHHPM_01592 5.8e-40 1.3.5.4 S FMN binding
KLGPHHPM_01593 1.6e-219 norA EGP Major facilitator Superfamily
KLGPHHPM_01594 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KLGPHHPM_01595 1.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
KLGPHHPM_01596 4.7e-106 J 2'-5' RNA ligase superfamily
KLGPHHPM_01597 2.2e-70 yqhY S Asp23 family, cell envelope-related function
KLGPHHPM_01598 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KLGPHHPM_01599 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KLGPHHPM_01600 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLGPHHPM_01601 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KLGPHHPM_01602 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLGPHHPM_01603 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KLGPHHPM_01604 3.3e-77 argR K Regulates arginine biosynthesis genes
KLGPHHPM_01605 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
KLGPHHPM_01606 1.7e-54
KLGPHHPM_01607 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KLGPHHPM_01608 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KLGPHHPM_01609 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KLGPHHPM_01610 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KLGPHHPM_01611 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KLGPHHPM_01612 9.6e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KLGPHHPM_01613 2.9e-131 stp 3.1.3.16 T phosphatase
KLGPHHPM_01614 0.0 KLT serine threonine protein kinase
KLGPHHPM_01615 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KLGPHHPM_01616 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KLGPHHPM_01617 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
KLGPHHPM_01618 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KLGPHHPM_01619 4.7e-58 asp S Asp23 family, cell envelope-related function
KLGPHHPM_01620 0.0 yloV S DAK2 domain fusion protein YloV
KLGPHHPM_01621 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KLGPHHPM_01622 3e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KLGPHHPM_01623 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLGPHHPM_01624 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KLGPHHPM_01625 0.0 smc D Required for chromosome condensation and partitioning
KLGPHHPM_01626 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KLGPHHPM_01627 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KLGPHHPM_01628 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KLGPHHPM_01629 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KLGPHHPM_01630 2e-39 ylqC S Belongs to the UPF0109 family
KLGPHHPM_01631 1.5e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KLGPHHPM_01632 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KLGPHHPM_01633 9.9e-261 yfnA E amino acid
KLGPHHPM_01634 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KLGPHHPM_01635 2.9e-34
KLGPHHPM_01636 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
KLGPHHPM_01637 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
KLGPHHPM_01638 9.5e-83
KLGPHHPM_01639 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KLGPHHPM_01640 7.5e-113 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLGPHHPM_01641 1.7e-37 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KLGPHHPM_01642 3e-50 S CRISPR-associated protein (Cas_Csn2)
KLGPHHPM_01643 1.1e-186 lacR K Transcriptional regulator
KLGPHHPM_01644 2.1e-107 lacS G Transporter
KLGPHHPM_01645 1.4e-223 lacS G Transporter
KLGPHHPM_01646 0.0 lacZ 3.2.1.23 G -beta-galactosidase
KLGPHHPM_01647 1.8e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KLGPHHPM_01648 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
KLGPHHPM_01649 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KLGPHHPM_01650 3.1e-223 mdtG EGP Major facilitator Superfamily
KLGPHHPM_01651 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
KLGPHHPM_01652 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KLGPHHPM_01655 8.4e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
KLGPHHPM_01656 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
KLGPHHPM_01657 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
KLGPHHPM_01658 0.0 trxB2 1.8.1.9 C Thioredoxin domain
KLGPHHPM_01659 4.6e-54 S Domain of unknown function (DUF4767)
KLGPHHPM_01660 1.6e-12
KLGPHHPM_01661 6.7e-134 cytX U Belongs to the purine-cytosine permease (2.A.39) family
KLGPHHPM_01662 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KLGPHHPM_01663 3.3e-46 gcvH E glycine cleavage
KLGPHHPM_01664 4.1e-220 rodA D Belongs to the SEDS family
KLGPHHPM_01665 1e-31 S Protein of unknown function (DUF2969)
KLGPHHPM_01666 1.9e-178 mbl D Cell shape determining protein MreB Mrl
KLGPHHPM_01667 2.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KLGPHHPM_01668 1.3e-33 ywzB S Protein of unknown function (DUF1146)
KLGPHHPM_01669 4.5e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KLGPHHPM_01670 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KLGPHHPM_01671 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KLGPHHPM_01672 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KLGPHHPM_01673 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLGPHHPM_01674 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KLGPHHPM_01675 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KLGPHHPM_01676 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
KLGPHHPM_01677 2.5e-231 pyrP F Permease
KLGPHHPM_01678 6.3e-129 yibF S overlaps another CDS with the same product name
KLGPHHPM_01679 9.9e-192 yibE S overlaps another CDS with the same product name
KLGPHHPM_01680 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLGPHHPM_01681 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KLGPHHPM_01682 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KLGPHHPM_01683 3.4e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KLGPHHPM_01684 7.5e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KLGPHHPM_01685 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KLGPHHPM_01686 6e-108 tdk 2.7.1.21 F thymidine kinase
KLGPHHPM_01687 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
KLGPHHPM_01688 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KLGPHHPM_01689 2.7e-223 arcD U Amino acid permease
KLGPHHPM_01690 2e-261 E Arginine ornithine antiporter
KLGPHHPM_01691 4.7e-79 argR K Regulates arginine biosynthesis genes
KLGPHHPM_01692 4.1e-239 arcA 3.5.3.6 E Arginine
KLGPHHPM_01693 3.9e-187 ampC V Beta-lactamase
KLGPHHPM_01694 1.9e-32
KLGPHHPM_01695 9.8e-29
KLGPHHPM_01696 4.5e-28
KLGPHHPM_01712 6.2e-31 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
KLGPHHPM_01713 5.3e-102 ica2 GT2 M Glycosyl transferase family group 2
KLGPHHPM_01714 3.9e-41
KLGPHHPM_01715 3.1e-95 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KLGPHHPM_01716 2.4e-23
KLGPHHPM_01717 1.1e-158 spoU 2.1.1.185 J Methyltransferase
KLGPHHPM_01718 4.9e-224 oxlT P Major Facilitator Superfamily
KLGPHHPM_01719 0.0 S SEC-C Motif Domain Protein
KLGPHHPM_01720 5.2e-50
KLGPHHPM_01721 6e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KLGPHHPM_01722 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KLGPHHPM_01723 5.7e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KLGPHHPM_01724 1.8e-226 clcA_2 P Chloride transporter, ClC family
KLGPHHPM_01725 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
KLGPHHPM_01726 7.6e-112 lssY 3.6.1.27 I Acid phosphatase homologues
KLGPHHPM_01728 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KLGPHHPM_01730 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLGPHHPM_01731 3.8e-159 endA V DNA/RNA non-specific endonuclease
KLGPHHPM_01732 1e-254 yifK E Amino acid permease
KLGPHHPM_01734 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KLGPHHPM_01735 1.1e-228 N Uncharacterized conserved protein (DUF2075)
KLGPHHPM_01736 4.6e-123 S SNARE associated Golgi protein
KLGPHHPM_01737 0.0 uvrA3 L excinuclease ABC, A subunit
KLGPHHPM_01738 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLGPHHPM_01739 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KLGPHHPM_01740 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KLGPHHPM_01741 8.1e-143 S DUF218 domain
KLGPHHPM_01742 0.0 ubiB S ABC1 family
KLGPHHPM_01743 2.2e-246 yhdP S Transporter associated domain
KLGPHHPM_01744 1.1e-74 copY K Copper transport repressor CopY TcrY
KLGPHHPM_01745 1.9e-245 EGP Major facilitator Superfamily
KLGPHHPM_01746 1e-73 yeaL S UPF0756 membrane protein
KLGPHHPM_01747 5.6e-79 yphH S Cupin domain
KLGPHHPM_01748 3.2e-83 C Flavodoxin
KLGPHHPM_01749 1.1e-158 K LysR substrate binding domain protein
KLGPHHPM_01750 1.9e-169 1.1.1.346 C Aldo keto reductase
KLGPHHPM_01751 2.1e-39 gcvR T Belongs to the UPF0237 family
KLGPHHPM_01752 8.5e-73 XK27_08635 S UPF0210 protein
KLGPHHPM_01753 3.9e-148 XK27_08635 S UPF0210 protein
KLGPHHPM_01754 1.5e-94 K Acetyltransferase (GNAT) domain
KLGPHHPM_01755 1.2e-160 S Alpha beta hydrolase
KLGPHHPM_01756 1.1e-158 gspA M family 8
KLGPHHPM_01757 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLGPHHPM_01758 3.8e-93
KLGPHHPM_01759 1.9e-161 degV S EDD domain protein, DegV family
KLGPHHPM_01760 0.0 FbpA K Fibronectin-binding protein
KLGPHHPM_01761 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
KLGPHHPM_01762 6.2e-207 carA 6.3.5.5 F Belongs to the CarA family
KLGPHHPM_01763 3.8e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KLGPHHPM_01764 2.9e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KLGPHHPM_01765 1.5e-65 esbA S Family of unknown function (DUF5322)
KLGPHHPM_01766 4.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
KLGPHHPM_01767 4.5e-185 M lysozyme activity
KLGPHHPM_01768 8.8e-16 S Bacteriophage holin family
KLGPHHPM_01769 4.8e-12
KLGPHHPM_01771 0.0 GT2,GT4 LM gp58-like protein
KLGPHHPM_01772 4.9e-52
KLGPHHPM_01773 0.0 M Phage tail tape measure protein TP901
KLGPHHPM_01774 5.2e-33
KLGPHHPM_01775 9e-58
KLGPHHPM_01776 6.5e-71 S Phage tail tube protein, TTP
KLGPHHPM_01777 2.1e-50
KLGPHHPM_01778 2.8e-78
KLGPHHPM_01779 3.5e-58
KLGPHHPM_01780 4.7e-35
KLGPHHPM_01781 9.4e-168 S Phage major capsid protein E
KLGPHHPM_01782 9.2e-54
KLGPHHPM_01783 4e-52 S Domain of unknown function (DUF4355)
KLGPHHPM_01784 7.3e-152 S Phage Mu protein F like protein
KLGPHHPM_01785 4e-220 S Phage portal protein, SPP1 Gp6-like
KLGPHHPM_01786 2.1e-217 S Terminase-like family
KLGPHHPM_01787 4.3e-118 xtmA L Terminase small subunit
KLGPHHPM_01789 3.4e-64 K Domain of unknown function (DUF4417)
KLGPHHPM_01796 1.7e-37
KLGPHHPM_01799 1.1e-61 rusA L Endodeoxyribonuclease RusA
KLGPHHPM_01800 3.1e-24
KLGPHHPM_01803 5.2e-78 Q DNA (cytosine-5-)-methyltransferase activity
KLGPHHPM_01805 4.7e-13
KLGPHHPM_01809 1.8e-50 S ORF6C domain
KLGPHHPM_01811 2.3e-27
KLGPHHPM_01812 5.4e-31 K Conserved phage C-terminus (Phg_2220_C)
KLGPHHPM_01813 1.8e-74 S Putative HNHc nuclease
KLGPHHPM_01814 1.7e-36 S Protein of unknown function (DUF669)
KLGPHHPM_01815 2.1e-83 S AAA domain
KLGPHHPM_01816 4.3e-84 S Bacteriophage Mu Gam like protein
KLGPHHPM_01819 5.3e-29 S sequence-specific DNA binding transcription factor activity
KLGPHHPM_01821 4.2e-32
KLGPHHPM_01828 4.4e-26 3.4.21.88 K Helix-turn-helix domain
KLGPHHPM_01829 8.6e-69 S Pfam:DUF955
KLGPHHPM_01830 1.7e-24 K transcriptional
KLGPHHPM_01831 1.4e-11 K Cro/C1-type HTH DNA-binding domain
KLGPHHPM_01833 2.6e-18
KLGPHHPM_01834 3.1e-38
KLGPHHPM_01835 1.5e-44
KLGPHHPM_01836 4.6e-104 L Belongs to the 'phage' integrase family
KLGPHHPM_01837 1.9e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KLGPHHPM_01838 1.1e-83 F Belongs to the NrdI family
KLGPHHPM_01839 3.5e-35
KLGPHHPM_01840 3.8e-70 yqeY S YqeY-like protein
KLGPHHPM_01841 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KLGPHHPM_01842 1.2e-264 glnPH2 P ABC transporter permease
KLGPHHPM_01843 1.2e-129 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
KLGPHHPM_01844 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
KLGPHHPM_01845 1e-164 yniA G Phosphotransferase enzyme family
KLGPHHPM_01846 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KLGPHHPM_01847 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KLGPHHPM_01848 1.2e-52
KLGPHHPM_01849 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KLGPHHPM_01850 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
KLGPHHPM_01851 2.8e-57
KLGPHHPM_01853 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KLGPHHPM_01855 3.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KLGPHHPM_01856 5.3e-275 pipD E Dipeptidase
KLGPHHPM_01857 0.0 S Peptidase, M23
KLGPHHPM_01858 0.0 bamA GM domain, Protein
KLGPHHPM_01859 7.9e-64 gntR1 K Transcriptional regulator, GntR family
KLGPHHPM_01860 2.5e-158 V ABC transporter, ATP-binding protein
KLGPHHPM_01861 3.7e-112
KLGPHHPM_01862 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
KLGPHHPM_01863 2.4e-99 S Pfam:DUF3816
KLGPHHPM_01864 0.0 clpE O Belongs to the ClpA ClpB family
KLGPHHPM_01865 2.9e-27
KLGPHHPM_01866 2.7e-39 ptsH G phosphocarrier protein HPR
KLGPHHPM_01867 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KLGPHHPM_01868 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
KLGPHHPM_01869 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
KLGPHHPM_01870 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLGPHHPM_01871 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
KLGPHHPM_01872 5.4e-181 galR K Transcriptional regulator
KLGPHHPM_01873 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KLGPHHPM_01874 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KLGPHHPM_01875 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
KLGPHHPM_01876 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
KLGPHHPM_01877 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
KLGPHHPM_01878 9.1e-36
KLGPHHPM_01879 2.6e-52
KLGPHHPM_01880 2.3e-204
KLGPHHPM_01881 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLGPHHPM_01882 8.9e-136 pnuC H nicotinamide mononucleotide transporter
KLGPHHPM_01883 3.2e-138 ytbE 1.1.1.346 S Aldo keto reductase
KLGPHHPM_01884 4.9e-125 K response regulator
KLGPHHPM_01885 5.5e-178 T PhoQ Sensor
KLGPHHPM_01886 9.8e-135 macB2 V ABC transporter, ATP-binding protein
KLGPHHPM_01887 0.0 ysaB V FtsX-like permease family
KLGPHHPM_01888 5.3e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
KLGPHHPM_01889 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KLGPHHPM_01890 4.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KLGPHHPM_01891 2.1e-197 EGP Major facilitator Superfamily
KLGPHHPM_01892 5.6e-86 ymdB S Macro domain protein
KLGPHHPM_01893 3.2e-110 K Helix-turn-helix domain
KLGPHHPM_01894 0.0 pepO 3.4.24.71 O Peptidase family M13
KLGPHHPM_01895 1.8e-47
KLGPHHPM_01896 2.5e-239 S Putative metallopeptidase domain
KLGPHHPM_01897 4.7e-205 3.1.3.1 S associated with various cellular activities
KLGPHHPM_01898 5.7e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KLGPHHPM_01899 5.4e-65 yeaO S Protein of unknown function, DUF488
KLGPHHPM_01901 2.9e-117 yrkL S Flavodoxin-like fold
KLGPHHPM_01902 9.5e-55
KLGPHHPM_01903 2e-15 S Domain of unknown function (DUF4767)
KLGPHHPM_01904 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLGPHHPM_01905 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
KLGPHHPM_01906 6.9e-49
KLGPHHPM_01907 7.6e-205 nrnB S DHHA1 domain
KLGPHHPM_01908 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
KLGPHHPM_01909 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
KLGPHHPM_01910 5.8e-106 NU mannosyl-glycoprotein
KLGPHHPM_01911 2.3e-142 S Putative ABC-transporter type IV
KLGPHHPM_01912 7.8e-272 S ABC transporter, ATP-binding protein
KLGPHHPM_01913 8.2e-48
KLGPHHPM_01914 4.1e-303 ytgP S Polysaccharide biosynthesis protein
KLGPHHPM_01915 4.9e-41
KLGPHHPM_01916 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KLGPHHPM_01917 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KLGPHHPM_01918 9.6e-92 tag 3.2.2.20 L glycosylase
KLGPHHPM_01919 1.5e-253 EGP Major facilitator Superfamily
KLGPHHPM_01920 4.3e-85 perR P Belongs to the Fur family
KLGPHHPM_01921 4.8e-233 cycA E Amino acid permease
KLGPHHPM_01922 2.8e-102 V VanZ like family
KLGPHHPM_01923 1e-23
KLGPHHPM_01924 7.7e-86 S Short repeat of unknown function (DUF308)
KLGPHHPM_01925 2.9e-78 S Psort location Cytoplasmic, score
KLGPHHPM_01926 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
KLGPHHPM_01927 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
KLGPHHPM_01928 8.1e-154 yeaE S Aldo keto
KLGPHHPM_01929 2.3e-93 lytE M LysM domain protein
KLGPHHPM_01930 0.0 oppD EP Psort location Cytoplasmic, score
KLGPHHPM_01931 3.6e-79 lytE M LysM domain protein
KLGPHHPM_01932 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
KLGPHHPM_01933 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KLGPHHPM_01934 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
KLGPHHPM_01935 1.5e-237 lmrB EGP Major facilitator Superfamily
KLGPHHPM_01936 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
KLGPHHPM_01944 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KLGPHHPM_01945 2.8e-117 udk 2.7.1.48 F Cytidine monophosphokinase
KLGPHHPM_01946 5.6e-115 rlpA M PFAM NLP P60 protein
KLGPHHPM_01947 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KLGPHHPM_01948 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KLGPHHPM_01949 2e-58 yodB K Transcriptional regulator, HxlR family
KLGPHHPM_01950 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KLGPHHPM_01951 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KLGPHHPM_01952 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KLGPHHPM_01953 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KLGPHHPM_01954 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KLGPHHPM_01955 4.4e-231 V MatE
KLGPHHPM_01956 7.4e-267 yjeM E Amino Acid
KLGPHHPM_01957 4.1e-278 arlS 2.7.13.3 T Histidine kinase
KLGPHHPM_01958 1.5e-121 K response regulator
KLGPHHPM_01959 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KLGPHHPM_01960 2.9e-99 yceD S Uncharacterized ACR, COG1399
KLGPHHPM_01961 6.1e-213 ylbM S Belongs to the UPF0348 family
KLGPHHPM_01962 1.7e-139 yqeM Q Methyltransferase
KLGPHHPM_01963 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KLGPHHPM_01964 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
KLGPHHPM_01965 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KLGPHHPM_01966 1.9e-47 yhbY J RNA-binding protein
KLGPHHPM_01967 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
KLGPHHPM_01968 1.8e-95 yqeG S HAD phosphatase, family IIIA
KLGPHHPM_01969 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KLGPHHPM_01970 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KLGPHHPM_01971 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KLGPHHPM_01972 1.1e-170 dnaI L Primosomal protein DnaI
KLGPHHPM_01973 1.4e-203 dnaB L replication initiation and membrane attachment
KLGPHHPM_01974 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KLGPHHPM_01975 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KLGPHHPM_01976 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KLGPHHPM_01977 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KLGPHHPM_01978 4.1e-116 yoaK S Protein of unknown function (DUF1275)
KLGPHHPM_01981 4.8e-39 L Integrase core domain
KLGPHHPM_01983 1.7e-103 dedA 3.1.3.1 S SNARE associated Golgi protein
KLGPHHPM_01984 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KLGPHHPM_01985 1.5e-80 K AsnC family
KLGPHHPM_01986 1.5e-80 uspA T universal stress protein
KLGPHHPM_01987 1.9e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
KLGPHHPM_01988 0.0 lacS G Transporter
KLGPHHPM_01989 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KLGPHHPM_01991 1.5e-225 S cog cog1373
KLGPHHPM_01992 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
KLGPHHPM_01993 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
KLGPHHPM_01994 4.7e-157 EG EamA-like transporter family
KLGPHHPM_01995 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
KLGPHHPM_01996 0.0 helD 3.6.4.12 L DNA helicase
KLGPHHPM_01997 1.2e-115 dedA S SNARE associated Golgi protein
KLGPHHPM_01998 4.2e-126 3.1.3.73 G phosphoglycerate mutase
KLGPHHPM_01999 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KLGPHHPM_02000 6.6e-35 S Transglycosylase associated protein
KLGPHHPM_02002 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KLGPHHPM_02003 3.2e-226 V domain protein
KLGPHHPM_02004 1.6e-94 K Transcriptional regulator (TetR family)
KLGPHHPM_02005 9.8e-39 pspC KT positive regulation of macromolecule biosynthetic process
KLGPHHPM_02006 2e-152
KLGPHHPM_02007 4e-17 3.2.1.14 GH18
KLGPHHPM_02008 1.5e-82 zur P Belongs to the Fur family
KLGPHHPM_02009 5.8e-103 gmk2 2.7.4.8 F Guanylate kinase
KLGPHHPM_02010 2.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
KLGPHHPM_02011 3e-254 yfnA E Amino Acid
KLGPHHPM_02012 3.6e-233 EGP Sugar (and other) transporter
KLGPHHPM_02013 9.9e-55
KLGPHHPM_02014 3.7e-43
KLGPHHPM_02015 1.8e-108
KLGPHHPM_02016 4.7e-207 potD P ABC transporter
KLGPHHPM_02017 6.5e-140 potC P ABC transporter permease
KLGPHHPM_02018 4.5e-146 potB P ABC transporter permease
KLGPHHPM_02019 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
KLGPHHPM_02020 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
KLGPHHPM_02021 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
KLGPHHPM_02022 0.0 pacL 3.6.3.8 P P-type ATPase
KLGPHHPM_02023 3.4e-85 dps P Belongs to the Dps family
KLGPHHPM_02024 2.8e-255 yagE E amino acid
KLGPHHPM_02025 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
KLGPHHPM_02026 0.0 uup S ABC transporter, ATP-binding protein
KLGPHHPM_02027 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KLGPHHPM_02028 1.6e-224 mtnE 2.6.1.83 E Aminotransferase
KLGPHHPM_02029 6.6e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KLGPHHPM_02030 1.2e-135 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KLGPHHPM_02031 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KLGPHHPM_02032 4.7e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KLGPHHPM_02033 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KLGPHHPM_02034 1.2e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
KLGPHHPM_02035 7e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
KLGPHHPM_02036 7.4e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KLGPHHPM_02037 3e-75
KLGPHHPM_02038 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
KLGPHHPM_02039 1.5e-25
KLGPHHPM_02040 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
KLGPHHPM_02041 7.2e-169 L transposase, IS605 OrfB family
KLGPHHPM_02042 9.4e-295 L PFAM plasmid pRiA4b ORF-3 family protein
KLGPHHPM_02043 2.1e-204 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
KLGPHHPM_02044 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KLGPHHPM_02045 1.9e-161 mleR K LysR family
KLGPHHPM_02046 4.8e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
KLGPHHPM_02047 1.4e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KLGPHHPM_02048 1.8e-267 frdC 1.3.5.4 C FAD binding domain
KLGPHHPM_02049 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
KLGPHHPM_02050 1e-159 mleR K LysR family
KLGPHHPM_02051 2e-250 yjjP S Putative threonine/serine exporter
KLGPHHPM_02052 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
KLGPHHPM_02053 7.2e-281 emrY EGP Major facilitator Superfamily
KLGPHHPM_02054 3.4e-188 I Alpha beta
KLGPHHPM_02055 4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
KLGPHHPM_02056 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KLGPHHPM_02058 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KLGPHHPM_02059 9.5e-119 S Domain of unknown function (DUF4811)
KLGPHHPM_02060 1.8e-268 lmrB EGP Major facilitator Superfamily
KLGPHHPM_02061 4.9e-73 merR K MerR HTH family regulatory protein
KLGPHHPM_02063 8.5e-20 QT PucR C-terminal helix-turn-helix domain
KLGPHHPM_02064 1.4e-96
KLGPHHPM_02065 1.1e-38 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
KLGPHHPM_02066 6.3e-25
KLGPHHPM_02067 4.8e-81 prrC S Protein conserved in bacteria
KLGPHHPM_02068 3.4e-171 L Integrase core domain
KLGPHHPM_02069 1.9e-46 L Transposase
KLGPHHPM_02070 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KLGPHHPM_02071 4.2e-130 IQ reductase
KLGPHHPM_02072 2e-150 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
KLGPHHPM_02073 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KLGPHHPM_02074 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KLGPHHPM_02075 4.2e-77 marR K Transcriptional regulator, MarR family
KLGPHHPM_02076 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KLGPHHPM_02078 9.6e-200 xerS L Belongs to the 'phage' integrase family
KLGPHHPM_02079 2.6e-242 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
KLGPHHPM_02080 1.4e-158 rssA S Phospholipase, patatin family
KLGPHHPM_02081 2.5e-118 L Integrase
KLGPHHPM_02082 1.2e-152 EG EamA-like transporter family
KLGPHHPM_02083 7.2e-30
KLGPHHPM_02084 4.2e-101 K DNA-templated transcription, initiation
KLGPHHPM_02085 7.3e-36

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)