ORF_ID e_value Gene_name EC_number CAZy COGs Description
DOILEAFA_00004 4.6e-45 L Transposase IS66 family
DOILEAFA_00023 9.6e-98
DOILEAFA_00024 6.8e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
DOILEAFA_00025 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DOILEAFA_00026 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
DOILEAFA_00027 4.7e-114 yjbH Q Thioredoxin
DOILEAFA_00028 7.8e-263 pipD E Dipeptidase
DOILEAFA_00029 3.4e-202 coiA 3.6.4.12 S Competence protein
DOILEAFA_00030 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
DOILEAFA_00031 3.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
DOILEAFA_00032 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
DOILEAFA_00033 1.3e-23 XK27_01125 L PFAM IS66 Orf2 family protein
DOILEAFA_00051 8.1e-114 lssY 3.6.1.27 I Acid phosphatase homologues
DOILEAFA_00052 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
DOILEAFA_00053 9.7e-228 clcA_2 P Chloride transporter, ClC family
DOILEAFA_00054 2.3e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DOILEAFA_00055 1.8e-145 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DOILEAFA_00056 2.9e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DOILEAFA_00057 3.6e-51
DOILEAFA_00058 0.0 S SEC-C Motif Domain Protein
DOILEAFA_00059 8.4e-114 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
DOILEAFA_00060 7.7e-76
DOILEAFA_00061 4.2e-175
DOILEAFA_00062 1.7e-174 fecB P Periplasmic binding protein
DOILEAFA_00063 5e-126 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
DOILEAFA_00064 8.6e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DOILEAFA_00065 1e-78 S Flavodoxin
DOILEAFA_00066 9.1e-63 moaE 2.8.1.12 H MoaE protein
DOILEAFA_00067 9.3e-34 moaD 2.8.1.12 H ThiS family
DOILEAFA_00068 7.8e-219 narK P Transporter, major facilitator family protein
DOILEAFA_00069 4.8e-144 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
DOILEAFA_00070 4.3e-175
DOILEAFA_00071 4.6e-18
DOILEAFA_00072 9.8e-115 nreC K PFAM regulatory protein LuxR
DOILEAFA_00073 4.5e-186 comP 2.7.13.3 F Sensor histidine kinase
DOILEAFA_00074 3e-44
DOILEAFA_00075 9.2e-93 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
DOILEAFA_00076 1.3e-74 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
DOILEAFA_00077 9.1e-223 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
DOILEAFA_00078 3.4e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
DOILEAFA_00079 4.8e-185 moeB 2.7.7.73, 2.7.7.80 H ThiF family
DOILEAFA_00080 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DOILEAFA_00081 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
DOILEAFA_00082 3.9e-99 narJ C nitrate reductase molybdenum cofactor assembly chaperone
DOILEAFA_00083 4.3e-129 narI 1.7.5.1 C Nitrate reductase
DOILEAFA_00084 1.5e-153 EG EamA-like transporter family
DOILEAFA_00085 2.5e-118 L Integrase
DOILEAFA_00086 5e-159 rssA S Phospholipase, patatin family
DOILEAFA_00087 3e-238 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
DOILEAFA_00088 4.6e-202 xerS L Belongs to the 'phage' integrase family
DOILEAFA_00090 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOILEAFA_00091 4.2e-77 marR K Transcriptional regulator, MarR family
DOILEAFA_00092 8.4e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DOILEAFA_00093 1.5e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOILEAFA_00094 6.5e-160 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
DOILEAFA_00095 3.5e-129 IQ reductase
DOILEAFA_00096 7.5e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
DOILEAFA_00097 2.9e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
DOILEAFA_00098 3.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
DOILEAFA_00099 1.7e-257 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
DOILEAFA_00100 6.5e-143 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DOILEAFA_00101 8e-140 accA 2.1.3.15, 6.4.1.2 I alpha subunit
DOILEAFA_00102 9.7e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
DOILEAFA_00109 1.8e-283 pipD E Dipeptidase
DOILEAFA_00110 1.9e-242 pbuX F xanthine permease
DOILEAFA_00111 1.1e-251 nhaC C Na H antiporter NhaC
DOILEAFA_00112 1.1e-284 S C4-dicarboxylate anaerobic carrier
DOILEAFA_00113 6.5e-127 pgm3 3.1.3.73 G phosphoglycerate mutase family
DOILEAFA_00114 1.3e-41
DOILEAFA_00115 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DOILEAFA_00116 4.2e-206 gldA 1.1.1.6 C dehydrogenase
DOILEAFA_00117 5.9e-125 S Alpha beta hydrolase
DOILEAFA_00118 7.9e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOILEAFA_00119 5.9e-103
DOILEAFA_00121 1.8e-124 yciB M ErfK YbiS YcfS YnhG
DOILEAFA_00122 1.6e-263 S Putative peptidoglycan binding domain
DOILEAFA_00123 4.6e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
DOILEAFA_00124 3.5e-88
DOILEAFA_00125 1.3e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
DOILEAFA_00126 1.8e-215 yttB EGP Major facilitator Superfamily
DOILEAFA_00127 3.7e-103
DOILEAFA_00128 1e-24
DOILEAFA_00129 1.2e-174 scrR K Transcriptional regulator, LacI family
DOILEAFA_00130 3.9e-240 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DOILEAFA_00131 4.1e-50 czrA K Transcriptional regulator, ArsR family
DOILEAFA_00132 1e-37
DOILEAFA_00133 0.0 yhcA V ABC transporter, ATP-binding protein
DOILEAFA_00134 4.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
DOILEAFA_00135 2.6e-181 hrtB V ABC transporter permease
DOILEAFA_00136 6.8e-87 ygfC K transcriptional regulator (TetR family)
DOILEAFA_00137 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
DOILEAFA_00138 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
DOILEAFA_00139 7.8e-30
DOILEAFA_00140 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DOILEAFA_00142 7.9e-16 V ABC transporter (permease)
DOILEAFA_00144 2.1e-227 yxiO S Vacuole effluxer Atg22 like
DOILEAFA_00145 4.1e-250 npp S type I phosphodiesterase nucleotide pyrophosphatase
DOILEAFA_00146 2.9e-241 E amino acid
DOILEAFA_00147 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOILEAFA_00149 1.8e-220 yxjG_1 E methionine synthase, vitamin-B12 independent
DOILEAFA_00150 1.6e-41 S Cytochrome B5
DOILEAFA_00151 5.4e-09 S Cytochrome B5
DOILEAFA_00152 2.4e-39 S Cytochrome B5
DOILEAFA_00153 6.4e-78 elaA S Gnat family
DOILEAFA_00154 7.8e-120 GM NmrA-like family
DOILEAFA_00155 2.5e-52 hxlR K Transcriptional regulator, HxlR family
DOILEAFA_00156 9.7e-109 XK27_02070 S Nitroreductase family
DOILEAFA_00157 1.8e-83 K Transcriptional regulator, HxlR family
DOILEAFA_00158 2.7e-236
DOILEAFA_00159 7.7e-211 EGP Major facilitator Superfamily
DOILEAFA_00160 4e-256 pepC 3.4.22.40 E aminopeptidase
DOILEAFA_00161 7.6e-112 ylbE GM NAD dependent epimerase dehydratase family protein
DOILEAFA_00162 0.0 pepN 3.4.11.2 E aminopeptidase
DOILEAFA_00163 1.2e-92 folT S ECF transporter, substrate-specific component
DOILEAFA_00164 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
DOILEAFA_00165 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
DOILEAFA_00166 1.8e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
DOILEAFA_00167 9.3e-201 2.7.7.65 T GGDEF domain
DOILEAFA_00168 3.9e-87
DOILEAFA_00169 4.9e-254 pgaC GT2 M Glycosyl transferase
DOILEAFA_00170 2.4e-142 T EAL domain
DOILEAFA_00171 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
DOILEAFA_00172 2.2e-63 yneR
DOILEAFA_00173 5.5e-161 akr5f 1.1.1.346 S reductase
DOILEAFA_00174 3.7e-133 K Transcriptional regulator
DOILEAFA_00175 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
DOILEAFA_00176 6.7e-155 ypuA S Protein of unknown function (DUF1002)
DOILEAFA_00177 8.9e-65 GM NAD(P)H-binding
DOILEAFA_00178 5.9e-94 padR K Virulence activator alpha C-term
DOILEAFA_00179 4.6e-94 padC Q Phenolic acid decarboxylase
DOILEAFA_00180 1.3e-151 S Alpha beta hydrolase
DOILEAFA_00181 5.6e-135 S Hydrolases of the alpha beta superfamily
DOILEAFA_00182 4.1e-87 lacA S transferase hexapeptide repeat
DOILEAFA_00183 2.5e-150 K Transcriptional regulator
DOILEAFA_00185 2.1e-16
DOILEAFA_00186 2.5e-83 C Flavodoxin
DOILEAFA_00188 2.4e-34 yphJ 4.1.1.44 S decarboxylase
DOILEAFA_00189 3.1e-10 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
DOILEAFA_00190 3.3e-114 P nitric oxide dioxygenase activity
DOILEAFA_00191 1.5e-107 S Peptidase propeptide and YPEB domain
DOILEAFA_00192 4.2e-229 T GHKL domain
DOILEAFA_00193 2.8e-120 T Transcriptional regulatory protein, C terminal
DOILEAFA_00194 1.5e-161 mleP3 S Membrane transport protein
DOILEAFA_00195 2.6e-118 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
DOILEAFA_00199 1.5e-223 2.7.13.3 T GHKL domain
DOILEAFA_00200 2.9e-118 K LytTr DNA-binding domain
DOILEAFA_00201 8.7e-26 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DOILEAFA_00202 1e-24
DOILEAFA_00203 2.4e-19 relB L Addiction module antitoxin, RelB DinJ family
DOILEAFA_00204 6.5e-87 XK27_08850 J Aminoacyl-tRNA editing domain
DOILEAFA_00205 1.3e-64 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOILEAFA_00206 1.1e-197 V Beta-lactamase
DOILEAFA_00207 1.9e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DOILEAFA_00208 8.3e-125 yhiD S MgtC family
DOILEAFA_00209 5.4e-118 S GyrI-like small molecule binding domain
DOILEAFA_00210 1.5e-07
DOILEAFA_00211 2.9e-111 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
DOILEAFA_00212 9.3e-43 azlD E Branched-chain amino acid transport
DOILEAFA_00213 1.2e-08
DOILEAFA_00214 1.4e-34 CP ABC-2 family transporter protein
DOILEAFA_00215 4.3e-83 V ABC transporter, ATP-binding protein
DOILEAFA_00216 7.3e-41 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
DOILEAFA_00217 1.9e-302 S amidohydrolase
DOILEAFA_00218 1.2e-165 S reductase
DOILEAFA_00220 8.9e-92 2.3.1.183 M Acetyltransferase GNAT family
DOILEAFA_00221 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DOILEAFA_00222 2.4e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
DOILEAFA_00223 6.9e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DOILEAFA_00224 0.0 asnB 6.3.5.4 E Asparagine synthase
DOILEAFA_00225 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
DOILEAFA_00226 2.8e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DOILEAFA_00227 1.7e-134 jag S R3H domain protein
DOILEAFA_00228 1e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOILEAFA_00229 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DOILEAFA_00230 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DOILEAFA_00231 2.9e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DOILEAFA_00232 8.5e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DOILEAFA_00233 8.4e-34 yaaA S S4 domain protein YaaA
DOILEAFA_00234 4.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DOILEAFA_00235 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOILEAFA_00236 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DOILEAFA_00237 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
DOILEAFA_00238 7e-77 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
DOILEAFA_00239 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DOILEAFA_00240 3.9e-95 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DOILEAFA_00241 1.4e-101 deoR K sugar-binding domain protein
DOILEAFA_00242 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
DOILEAFA_00243 2e-74 rplI J Binds to the 23S rRNA
DOILEAFA_00244 4.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DOILEAFA_00245 6.4e-205 yttB EGP Major facilitator Superfamily
DOILEAFA_00246 3.2e-58
DOILEAFA_00247 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
DOILEAFA_00248 1.3e-123 Z012_01130 S Fic/DOC family
DOILEAFA_00250 4.7e-73 K helix_turn_helix multiple antibiotic resistance protein
DOILEAFA_00251 4.8e-310 lmrA 3.6.3.44 V ABC transporter
DOILEAFA_00253 3.1e-130 K response regulator
DOILEAFA_00254 0.0 vicK 2.7.13.3 T Histidine kinase
DOILEAFA_00255 1.3e-248 yycH S YycH protein
DOILEAFA_00256 5.4e-150 yycI S YycH protein
DOILEAFA_00257 4.5e-154 vicX 3.1.26.11 S domain protein
DOILEAFA_00258 2.7e-217 htrA 3.4.21.107 O serine protease
DOILEAFA_00259 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
DOILEAFA_00260 5.5e-178 ABC-SBP S ABC transporter
DOILEAFA_00261 2.3e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DOILEAFA_00263 2.2e-96 S reductase
DOILEAFA_00264 6.5e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
DOILEAFA_00265 4e-147 E Glyoxalase-like domain
DOILEAFA_00266 4.6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOILEAFA_00267 2e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
DOILEAFA_00268 1.8e-145 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DOILEAFA_00269 3.7e-128 V ABC transporter
DOILEAFA_00270 2.7e-214 bacI V MacB-like periplasmic core domain
DOILEAFA_00271 4.6e-35
DOILEAFA_00272 3.4e-266 S Putative peptidoglycan binding domain
DOILEAFA_00275 8.4e-174 2.7.13.3 T GHKL domain
DOILEAFA_00276 4e-99 K LytTr DNA-binding domain
DOILEAFA_00282 1.7e-240 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
DOILEAFA_00284 8.5e-75 osmC O OsmC-like protein
DOILEAFA_00285 4.7e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOILEAFA_00286 7.7e-219 patA 2.6.1.1 E Aminotransferase
DOILEAFA_00287 2.7e-32
DOILEAFA_00288 0.0 clpL O associated with various cellular activities
DOILEAFA_00289 1.7e-207 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
DOILEAFA_00291 1.4e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
DOILEAFA_00292 9.4e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOILEAFA_00293 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
DOILEAFA_00294 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
DOILEAFA_00295 3.9e-173 malR K Transcriptional regulator, LacI family
DOILEAFA_00296 9.1e-212 phbA 2.3.1.9 I Belongs to the thiolase family
DOILEAFA_00297 6.9e-256 malT G Major Facilitator
DOILEAFA_00298 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
DOILEAFA_00299 2.1e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
DOILEAFA_00300 1.3e-87 2.7.6.5 T Region found in RelA / SpoT proteins
DOILEAFA_00301 4.9e-114 K response regulator
DOILEAFA_00302 5.6e-220 sptS 2.7.13.3 T Histidine kinase
DOILEAFA_00303 5.7e-206 yfeO P Voltage gated chloride channel
DOILEAFA_00304 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
DOILEAFA_00305 7.8e-137 puuD S peptidase C26
DOILEAFA_00306 2.3e-167 yvgN C Aldo keto reductase
DOILEAFA_00307 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
DOILEAFA_00308 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
DOILEAFA_00309 7.1e-261 nox C NADH oxidase
DOILEAFA_00310 4.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOILEAFA_00311 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DOILEAFA_00312 3.9e-86
DOILEAFA_00313 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
DOILEAFA_00315 9.6e-115 K Transcriptional regulator, TetR family
DOILEAFA_00316 2.2e-72
DOILEAFA_00317 2.3e-271 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
DOILEAFA_00318 2.7e-277 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
DOILEAFA_00319 1.2e-292 M domain protein
DOILEAFA_00320 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DOILEAFA_00321 1.5e-266 G Major Facilitator
DOILEAFA_00322 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DOILEAFA_00323 6.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
DOILEAFA_00324 6.8e-259 G Major Facilitator
DOILEAFA_00325 3.9e-179 K Transcriptional regulator, LacI family
DOILEAFA_00326 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOILEAFA_00327 6.4e-102 nqr 1.5.1.36 S reductase
DOILEAFA_00328 1.6e-198 XK27_09615 S reductase
DOILEAFA_00329 6.8e-178 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DOILEAFA_00330 7.8e-24
DOILEAFA_00331 0.0
DOILEAFA_00332 0.0
DOILEAFA_00333 4.4e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
DOILEAFA_00334 1.8e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DOILEAFA_00335 6.3e-102 fic D Fic/DOC family
DOILEAFA_00336 5.6e-71
DOILEAFA_00337 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
DOILEAFA_00338 2.2e-93 L nuclease
DOILEAFA_00339 0.0 sbcC L Putative exonuclease SbcCD, C subunit
DOILEAFA_00340 1.2e-210 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
DOILEAFA_00341 3.6e-176 M Glycosyl hydrolases family 25
DOILEAFA_00342 1.5e-143 ywqE 3.1.3.48 GM PHP domain protein
DOILEAFA_00343 0.0 snf 2.7.11.1 KL domain protein
DOILEAFA_00345 2.7e-32
DOILEAFA_00347 2.6e-250 mmuP E amino acid
DOILEAFA_00348 1.2e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
DOILEAFA_00349 2.1e-70 O Preprotein translocase subunit SecB
DOILEAFA_00351 4.5e-44
DOILEAFA_00352 1.4e-47 XK27_01125 L PFAM IS66 Orf2 family protein
DOILEAFA_00354 5.2e-143 K IrrE N-terminal-like domain
DOILEAFA_00355 5.7e-71
DOILEAFA_00356 1.2e-144 L Transposase
DOILEAFA_00358 5.1e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DOILEAFA_00359 1.7e-159 S Membrane protein involved in the export of O-antigen and teichoic acid
DOILEAFA_00360 1.3e-63 S Core-2/I-Branching enzyme
DOILEAFA_00361 2e-26 M Glycosyltransferase like family 2
DOILEAFA_00363 9.5e-147 M Glycosyl transferases group 1
DOILEAFA_00364 3.1e-160 G Glycosyltransferase Family 4
DOILEAFA_00365 1.4e-146 rgpAc GT4 M Domain of unknown function (DUF1972)
DOILEAFA_00366 2.1e-196 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DOILEAFA_00367 4.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
DOILEAFA_00368 4.1e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DOILEAFA_00369 2.1e-109 rfbP M Bacterial sugar transferase
DOILEAFA_00370 2.8e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
DOILEAFA_00371 1.5e-142 epsB M biosynthesis protein
DOILEAFA_00372 2e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOILEAFA_00373 1.2e-67 K Transcriptional regulator, HxlR family
DOILEAFA_00374 2e-115
DOILEAFA_00375 2.2e-102 K DNA-templated transcription, initiation
DOILEAFA_00376 3.1e-34
DOILEAFA_00377 5.8e-83
DOILEAFA_00378 1.6e-290 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DOILEAFA_00379 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
DOILEAFA_00380 0.0 yjbQ P TrkA C-terminal domain protein
DOILEAFA_00381 3.9e-270 pipD E Dipeptidase
DOILEAFA_00383 1.1e-237 L Transposase
DOILEAFA_00384 1.6e-132 fat 3.1.2.21 I Acyl-ACP thioesterase
DOILEAFA_00385 7.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DOILEAFA_00386 5.9e-58 yabA L Involved in initiation control of chromosome replication
DOILEAFA_00387 5.7e-186 holB 2.7.7.7 L DNA polymerase III
DOILEAFA_00388 2.9e-51 yaaQ S Cyclic-di-AMP receptor
DOILEAFA_00389 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DOILEAFA_00390 4.8e-38 S Protein of unknown function (DUF2508)
DOILEAFA_00391 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DOILEAFA_00392 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DOILEAFA_00393 4.9e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOILEAFA_00394 1.3e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DOILEAFA_00395 9.9e-35 nrdH O Glutaredoxin
DOILEAFA_00396 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOILEAFA_00397 1.1e-197 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DOILEAFA_00398 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DOILEAFA_00399 2.3e-131 S Putative adhesin
DOILEAFA_00400 1.9e-83 XK27_06920 S Protein of unknown function (DUF1700)
DOILEAFA_00401 1.1e-56 K transcriptional regulator PadR family
DOILEAFA_00402 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DOILEAFA_00404 3.4e-48
DOILEAFA_00405 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DOILEAFA_00406 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DOILEAFA_00407 7.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DOILEAFA_00408 3.4e-244 M Glycosyl transferase family group 2
DOILEAFA_00410 4.6e-227 aadAT EK Aminotransferase, class I
DOILEAFA_00411 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DOILEAFA_00412 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DOILEAFA_00413 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
DOILEAFA_00414 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DOILEAFA_00415 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DOILEAFA_00416 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOILEAFA_00417 7.2e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
DOILEAFA_00418 1.3e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOILEAFA_00419 5e-207 yacL S domain protein
DOILEAFA_00420 1.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DOILEAFA_00421 1.4e-98 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
DOILEAFA_00422 3.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
DOILEAFA_00423 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DOILEAFA_00424 1.3e-267 pepC 3.4.22.40 E Peptidase C1-like family
DOILEAFA_00425 1.6e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
DOILEAFA_00426 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOILEAFA_00427 1.1e-119 tcyB E ABC transporter
DOILEAFA_00428 1.7e-215 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
DOILEAFA_00429 3.1e-169 I alpha/beta hydrolase fold
DOILEAFA_00430 1.6e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOILEAFA_00431 0.0 S Bacterial membrane protein, YfhO
DOILEAFA_00432 5.9e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
DOILEAFA_00433 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
DOILEAFA_00434 1.1e-237 L Transposase
DOILEAFA_00435 1.1e-237 L Transposase
DOILEAFA_00436 1.1e-137 K LysR substrate binding domain
DOILEAFA_00437 5.6e-53 azlD S branched-chain amino acid
DOILEAFA_00438 1.9e-140 azlC E AzlC protein
DOILEAFA_00439 1.8e-201 hpk31 2.7.13.3 T Histidine kinase
DOILEAFA_00440 3.8e-125 K response regulator
DOILEAFA_00441 2.7e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
DOILEAFA_00442 1.3e-171 deoR K sugar-binding domain protein
DOILEAFA_00443 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
DOILEAFA_00444 2e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
DOILEAFA_00445 2e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
DOILEAFA_00446 1.3e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DOILEAFA_00447 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
DOILEAFA_00448 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DOILEAFA_00449 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
DOILEAFA_00450 1.6e-152 spo0J K Belongs to the ParB family
DOILEAFA_00451 1.4e-139 soj D Sporulation initiation inhibitor
DOILEAFA_00452 1.1e-149 noc K Belongs to the ParB family
DOILEAFA_00453 1.2e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DOILEAFA_00454 1.9e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
DOILEAFA_00455 2.7e-171 rihC 3.2.2.1 F Nucleoside
DOILEAFA_00456 1e-218 nupG F Nucleoside transporter
DOILEAFA_00457 7.7e-223 cycA E Amino acid permease
DOILEAFA_00458 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOILEAFA_00459 6.7e-265 glnP P ABC transporter
DOILEAFA_00460 9.3e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DOILEAFA_00461 1.1e-237 L Transposase
DOILEAFA_00462 2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOILEAFA_00463 1.1e-265 glnPH2 P ABC transporter permease
DOILEAFA_00464 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
DOILEAFA_00465 2.1e-68 yqeY S YqeY-like protein
DOILEAFA_00466 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DOILEAFA_00467 1.1e-236 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DOILEAFA_00468 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
DOILEAFA_00469 1.5e-90 bioY S BioY family
DOILEAFA_00470 6.6e-176 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
DOILEAFA_00471 6.9e-184 phoH T phosphate starvation-inducible protein PhoH
DOILEAFA_00472 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DOILEAFA_00473 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
DOILEAFA_00474 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DOILEAFA_00475 1.8e-147 recO L Involved in DNA repair and RecF pathway recombination
DOILEAFA_00476 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
DOILEAFA_00477 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
DOILEAFA_00478 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DOILEAFA_00479 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DOILEAFA_00480 9.1e-220 patA 2.6.1.1 E Aminotransferase
DOILEAFA_00481 1.7e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
DOILEAFA_00482 2.3e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DOILEAFA_00483 3.9e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
DOILEAFA_00484 2.3e-30 S Protein of unknown function (DUF2929)
DOILEAFA_00485 0.0 dnaE 2.7.7.7 L DNA polymerase
DOILEAFA_00486 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
DOILEAFA_00487 9.3e-169 cvfB S S1 domain
DOILEAFA_00488 1.4e-164 xerD D recombinase XerD
DOILEAFA_00489 4.7e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
DOILEAFA_00490 2.9e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DOILEAFA_00491 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DOILEAFA_00492 2.9e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DOILEAFA_00493 1.1e-101 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DOILEAFA_00494 2.4e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
DOILEAFA_00495 5.2e-270 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
DOILEAFA_00496 3.3e-26 M Lysin motif
DOILEAFA_00497 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
DOILEAFA_00498 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
DOILEAFA_00499 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
DOILEAFA_00500 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DOILEAFA_00501 1.7e-235 S Tetratricopeptide repeat protein
DOILEAFA_00502 2.4e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DOILEAFA_00503 0.0 yfmR S ABC transporter, ATP-binding protein
DOILEAFA_00504 8.5e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DOILEAFA_00505 1.1e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DOILEAFA_00506 1.2e-112 hlyIII S protein, hemolysin III
DOILEAFA_00507 3.8e-151 DegV S EDD domain protein, DegV family
DOILEAFA_00508 8e-171 ypmR E lipolytic protein G-D-S-L family
DOILEAFA_00509 6.9e-107 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
DOILEAFA_00510 4.4e-35 yozE S Belongs to the UPF0346 family
DOILEAFA_00511 8.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DOILEAFA_00512 8.5e-142 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOILEAFA_00513 2.7e-160 dprA LU DNA protecting protein DprA
DOILEAFA_00514 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DOILEAFA_00515 4.6e-168 lacX 5.1.3.3 G Aldose 1-epimerase
DOILEAFA_00516 2.3e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
DOILEAFA_00517 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOILEAFA_00518 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
DOILEAFA_00519 3.5e-82 F NUDIX domain
DOILEAFA_00520 1.1e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
DOILEAFA_00521 4.1e-68 yqkB S Belongs to the HesB IscA family
DOILEAFA_00522 1.6e-49
DOILEAFA_00524 5.9e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
DOILEAFA_00525 8.7e-63 asp S Asp23 family, cell envelope-related function
DOILEAFA_00526 2.3e-24
DOILEAFA_00527 4.2e-95
DOILEAFA_00528 2.7e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
DOILEAFA_00529 1.2e-183 K Transcriptional regulator, LacI family
DOILEAFA_00530 1.3e-233 gntT EG Gluconate
DOILEAFA_00531 4.5e-296 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
DOILEAFA_00532 4.9e-96 K Acetyltransferase (GNAT) domain
DOILEAFA_00533 4.2e-47
DOILEAFA_00534 2.4e-22
DOILEAFA_00535 9.4e-70 pldB 3.1.1.5 I Serine aminopeptidase, S33
DOILEAFA_00536 5.1e-75 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
DOILEAFA_00537 2.9e-22 K MerR family regulatory protein
DOILEAFA_00538 2.9e-44
DOILEAFA_00539 1.6e-56 yhaI S Protein of unknown function (DUF805)
DOILEAFA_00540 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
DOILEAFA_00541 4.6e-294 hsdM 2.1.1.72 V type I restriction-modification system
DOILEAFA_00542 9.3e-71 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
DOILEAFA_00543 2e-177 L Belongs to the 'phage' integrase family
DOILEAFA_00544 6.9e-68 3.1.21.3 V Type I restriction modification DNA specificity domain
DOILEAFA_00545 5.7e-38 higA K Helix-turn-helix XRE-family like proteins
DOILEAFA_00546 1.8e-44 S RelE-like toxin of type II toxin-antitoxin system HigB
DOILEAFA_00547 7.8e-53 hsdS_1 3.1.21.3 V Type I restriction modification DNA specificity domain
DOILEAFA_00548 3.7e-168 L restriction endonuclease
DOILEAFA_00549 6.3e-60 L restriction endonuclease
DOILEAFA_00550 3.2e-77 mrr L restriction endonuclease
DOILEAFA_00551 0.0 L PLD-like domain
DOILEAFA_00553 6.9e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DOILEAFA_00554 1.8e-182 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DOILEAFA_00555 3.7e-92 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
DOILEAFA_00556 7.2e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
DOILEAFA_00557 2.2e-76 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
DOILEAFA_00558 5.6e-103 T Ion transport 2 domain protein
DOILEAFA_00559 0.0 S Bacterial membrane protein YfhO
DOILEAFA_00560 1.4e-207 G Transporter, major facilitator family protein
DOILEAFA_00561 1e-107 yvrI K sigma factor activity
DOILEAFA_00562 1.7e-63 ydiI Q Thioesterase superfamily
DOILEAFA_00563 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DOILEAFA_00564 1.6e-274 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
DOILEAFA_00565 2.1e-117 L hmm pf00665
DOILEAFA_00566 1.4e-127 L Helix-turn-helix domain
DOILEAFA_00567 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DOILEAFA_00568 1.2e-31 feoA P FeoA domain
DOILEAFA_00569 6.5e-145 sufC O FeS assembly ATPase SufC
DOILEAFA_00570 7.8e-241 sufD O FeS assembly protein SufD
DOILEAFA_00571 3.3e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DOILEAFA_00572 3.2e-80 nifU C SUF system FeS assembly protein, NifU family
DOILEAFA_00573 1.4e-270 sufB O assembly protein SufB
DOILEAFA_00574 8.1e-57 yitW S Iron-sulfur cluster assembly protein
DOILEAFA_00575 2.7e-160 hipB K Helix-turn-helix
DOILEAFA_00576 4.9e-114 nreC K PFAM regulatory protein LuxR
DOILEAFA_00577 9.2e-39 S Cytochrome B5
DOILEAFA_00578 6.4e-156 yitU 3.1.3.104 S hydrolase
DOILEAFA_00579 5.5e-261 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
DOILEAFA_00580 8.9e-148 f42a O Band 7 protein
DOILEAFA_00581 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
DOILEAFA_00582 1.1e-130 lytT K response regulator receiver
DOILEAFA_00583 1.9e-66 lrgA S LrgA family
DOILEAFA_00584 4.5e-124 lrgB M LrgB-like family
DOILEAFA_00585 6.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DOILEAFA_00586 4.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
DOILEAFA_00587 2e-191 galR K Periplasmic binding protein-like domain
DOILEAFA_00588 0.0 rafA 3.2.1.22 G alpha-galactosidase
DOILEAFA_00589 3.8e-87 S Protein of unknown function (DUF1440)
DOILEAFA_00590 2.9e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
DOILEAFA_00591 7.1e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
DOILEAFA_00592 1e-168 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
DOILEAFA_00593 3.9e-173 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
DOILEAFA_00594 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
DOILEAFA_00595 2.9e-85 ypmB S Protein conserved in bacteria
DOILEAFA_00596 3e-125 dnaD L DnaD domain protein
DOILEAFA_00597 3.9e-162 EG EamA-like transporter family
DOILEAFA_00598 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
DOILEAFA_00599 7.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
DOILEAFA_00600 9.8e-103 ypsA S Belongs to the UPF0398 family
DOILEAFA_00601 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
DOILEAFA_00602 1.2e-82 F Belongs to the NrdI family
DOILEAFA_00603 4.3e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
DOILEAFA_00604 1.8e-71 rnhA 3.1.26.4 L Ribonuclease HI
DOILEAFA_00605 1.5e-65 esbA S Family of unknown function (DUF5322)
DOILEAFA_00606 3.7e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DOILEAFA_00607 4.8e-176 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOILEAFA_00608 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
DOILEAFA_00609 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
DOILEAFA_00610 0.0 FbpA K Fibronectin-binding protein
DOILEAFA_00611 6.4e-162 degV S EDD domain protein, DegV family
DOILEAFA_00612 1.9e-92
DOILEAFA_00613 2.3e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOILEAFA_00614 9.5e-77 tlpA2 L Transposase IS200 like
DOILEAFA_00615 3.9e-229 L transposase, IS605 OrfB family
DOILEAFA_00616 1.1e-158 gspA M family 8
DOILEAFA_00617 4.4e-160 S Alpha beta hydrolase
DOILEAFA_00618 5.3e-95 K Acetyltransferase (GNAT) domain
DOILEAFA_00619 8.7e-243 XK27_08635 S UPF0210 protein
DOILEAFA_00620 2.1e-39 gcvR T Belongs to the UPF0237 family
DOILEAFA_00621 2.9e-170 1.1.1.346 C Aldo keto reductase
DOILEAFA_00622 1.6e-160 K LysR substrate binding domain protein
DOILEAFA_00623 7.7e-85 C Flavodoxin
DOILEAFA_00624 1e-80 yphH S Cupin domain
DOILEAFA_00625 4.5e-74 yeaL S UPF0756 membrane protein
DOILEAFA_00626 1.1e-245 EGP Major facilitator Superfamily
DOILEAFA_00627 1.9e-74 copY K Copper transport repressor CopY TcrY
DOILEAFA_00628 8.5e-246 yhdP S Transporter associated domain
DOILEAFA_00629 0.0 ubiB S ABC1 family
DOILEAFA_00630 1.9e-144 S DUF218 domain
DOILEAFA_00631 2.4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DOILEAFA_00632 1.6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOILEAFA_00633 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOILEAFA_00634 0.0 uvrA3 L excinuclease ABC, A subunit
DOILEAFA_00635 5.1e-122 S SNARE associated Golgi protein
DOILEAFA_00636 1.3e-221 N Uncharacterized conserved protein (DUF2075)
DOILEAFA_00637 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DOILEAFA_00639 1e-254 yifK E Amino acid permease
DOILEAFA_00640 1.4e-150 endA V DNA/RNA non-specific endonuclease
DOILEAFA_00641 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOILEAFA_00642 3.5e-42 ybaN S Protein of unknown function (DUF454)
DOILEAFA_00643 2.6e-71 S Protein of unknown function (DUF3290)
DOILEAFA_00644 2e-112 yviA S Protein of unknown function (DUF421)
DOILEAFA_00645 2.6e-163 S Alpha/beta hydrolase of unknown function (DUF915)
DOILEAFA_00646 1.2e-18
DOILEAFA_00647 5.2e-89 ntd 2.4.2.6 F Nucleoside
DOILEAFA_00648 8.1e-151 3.1.3.102, 3.1.3.104 S hydrolase
DOILEAFA_00649 3e-49 yrvD S Pfam:DUF1049
DOILEAFA_00651 1.1e-35 S Phage derived protein Gp49-like (DUF891)
DOILEAFA_00652 8.5e-20 K Helix-turn-helix XRE-family like proteins
DOILEAFA_00653 1.7e-162 I alpha/beta hydrolase fold
DOILEAFA_00654 3.7e-114 frnE Q DSBA-like thioredoxin domain
DOILEAFA_00655 6.2e-55
DOILEAFA_00659 2.8e-19
DOILEAFA_00660 5e-263 dtpT U amino acid peptide transporter
DOILEAFA_00661 5.2e-153 yjjH S Calcineurin-like phosphoesterase
DOILEAFA_00664 7.4e-115
DOILEAFA_00665 7.7e-250 EGP Major facilitator Superfamily
DOILEAFA_00666 8.8e-298 aspT P Predicted Permease Membrane Region
DOILEAFA_00667 3.4e-129 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
DOILEAFA_00668 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
DOILEAFA_00669 9.1e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DOILEAFA_00670 2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
DOILEAFA_00671 0.0 yhgF K Tex-like protein N-terminal domain protein
DOILEAFA_00672 3.3e-85 ydcK S Belongs to the SprT family
DOILEAFA_00674 1.1e-237 L Transposase
DOILEAFA_00675 3.2e-243 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
DOILEAFA_00676 8.6e-08 S MerR HTH family regulatory protein
DOILEAFA_00677 3.6e-37 DJ ParE toxin of type II toxin-antitoxin system, parDE
DOILEAFA_00678 1.4e-20
DOILEAFA_00679 5.7e-51 S Protein conserved in bacteria
DOILEAFA_00680 1.7e-269 V Type II restriction enzyme, methylase subunits
DOILEAFA_00681 1.5e-238 L Transposase
DOILEAFA_00684 8.3e-35 XK27_00515 D Glucan-binding protein C
DOILEAFA_00686 1.9e-13 sdrF M domain protein
DOILEAFA_00688 3.4e-11 ftsZ D Cell surface antigen C-terminus
DOILEAFA_00689 1.1e-92 L Belongs to the 'phage' integrase family
DOILEAFA_00690 3.7e-16 D nuclear chromosome segregation
DOILEAFA_00693 6.6e-32
DOILEAFA_00695 2.9e-83 soj D CobQ CobB MinD ParA nucleotide binding domain protein
DOILEAFA_00696 3.2e-14 S Replication initiator protein A (RepA) N-terminus
DOILEAFA_00697 1.6e-32 srtA 3.4.22.70 M Sortase family
DOILEAFA_00701 8.3e-49 O ATP-dependent Clp protease ATP-binding subunit clpC
DOILEAFA_00707 8.3e-08
DOILEAFA_00709 1.9e-98 2.1.1.37 L C-5 cytosine-specific DNA methylase
DOILEAFA_00710 4.6e-40 M Prophage endopeptidase tail
DOILEAFA_00714 2.5e-92 S Putative peptidoglycan binding domain
DOILEAFA_00717 1.1e-25 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
DOILEAFA_00722 1.7e-22 ftsK D Belongs to the FtsK SpoIIIE SftA family
DOILEAFA_00727 1.8e-22
DOILEAFA_00728 1.3e-17 N HicA toxin of bacterial toxin-antitoxin,
DOILEAFA_00729 1.4e-56 S HicB_like antitoxin of bacterial toxin-antitoxin system
DOILEAFA_00730 3.6e-08
DOILEAFA_00733 4.3e-13 K prlF antitoxin for toxin YhaV_toxin
DOILEAFA_00734 8.5e-33 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
DOILEAFA_00735 1.6e-20
DOILEAFA_00736 3.8e-38 L Transposase IS200 like
DOILEAFA_00737 2e-174 L transposase, IS605 OrfB family
DOILEAFA_00738 2.1e-08
DOILEAFA_00739 2.4e-56 L Lactococcus lactis RepB C-terminus
DOILEAFA_00748 2.2e-15
DOILEAFA_00752 1.6e-13 XK27_11280 S Psort location CytoplasmicMembrane, score
DOILEAFA_00753 3.1e-178 XK27_11280 S Psort location CytoplasmicMembrane, score
DOILEAFA_00775 6.9e-73 XK27_00160 S Domain of unknown function (DUF5052)
DOILEAFA_00776 2.6e-34 S Uncharacterized protein conserved in bacteria (DUF2325)
DOILEAFA_00782 4.8e-23 higA K Addiction module antidote protein, HigA
DOILEAFA_00783 2.7e-57 L Probable transposase
DOILEAFA_00784 1.8e-134 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DOILEAFA_00785 1.7e-64 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DOILEAFA_00786 4.4e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DOILEAFA_00787 1.3e-218 patA 2.6.1.1 E Aminotransferase
DOILEAFA_00788 6.2e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DOILEAFA_00789 3.8e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DOILEAFA_00790 1.6e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
DOILEAFA_00791 6.7e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
DOILEAFA_00792 1.9e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DOILEAFA_00793 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
DOILEAFA_00794 1.4e-181 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DOILEAFA_00795 8.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOILEAFA_00796 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
DOILEAFA_00797 9e-119 S Repeat protein
DOILEAFA_00798 2.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
DOILEAFA_00799 3.9e-217 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
DOILEAFA_00800 7.5e-58 XK27_04120 S Putative amino acid metabolism
DOILEAFA_00801 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
DOILEAFA_00802 1.7e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DOILEAFA_00804 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
DOILEAFA_00805 4.2e-32 cspA K Cold shock protein
DOILEAFA_00806 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DOILEAFA_00807 1.9e-42 divIVA D DivIVA domain protein
DOILEAFA_00808 2.2e-145 ylmH S S4 domain protein
DOILEAFA_00809 3.2e-40 yggT S YGGT family
DOILEAFA_00810 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DOILEAFA_00811 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DOILEAFA_00812 3.3e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
DOILEAFA_00813 3e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
DOILEAFA_00814 7.8e-205 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DOILEAFA_00815 1.9e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DOILEAFA_00816 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DOILEAFA_00817 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
DOILEAFA_00818 1.5e-56 ftsL D Cell division protein FtsL
DOILEAFA_00819 1e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DOILEAFA_00820 3.1e-77 mraZ K Belongs to the MraZ family
DOILEAFA_00821 1.7e-57
DOILEAFA_00822 1.2e-10 S Protein of unknown function (DUF4044)
DOILEAFA_00823 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
DOILEAFA_00824 1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DOILEAFA_00825 2e-160 rrmA 2.1.1.187 H Methyltransferase
DOILEAFA_00826 6.6e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
DOILEAFA_00827 9.7e-169 corA P CorA-like Mg2+ transporter protein
DOILEAFA_00828 2e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
DOILEAFA_00829 2.3e-131 terC P membrane
DOILEAFA_00830 2.1e-54 trxA O Belongs to the thioredoxin family
DOILEAFA_00831 5.4e-237 mepA V MATE efflux family protein
DOILEAFA_00832 6.8e-56 K Transcriptional regulator, ArsR family
DOILEAFA_00833 3.1e-93 P Cadmium resistance transporter
DOILEAFA_00834 3.1e-136 XK27_08845 S ABC transporter, ATP-binding protein
DOILEAFA_00835 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
DOILEAFA_00836 2.9e-182 ABC-SBP S ABC transporter
DOILEAFA_00837 5e-73 M PFAM NLP P60 protein
DOILEAFA_00839 8.6e-13 relB L RelB antitoxin
DOILEAFA_00840 6.6e-48
DOILEAFA_00841 1.9e-273 S ABC transporter, ATP-binding protein
DOILEAFA_00842 3.5e-143 S Putative ABC-transporter type IV
DOILEAFA_00843 2e-106 NU mannosyl-glycoprotein
DOILEAFA_00844 5.4e-248 brnQ U Component of the transport system for branched-chain amino acids
DOILEAFA_00845 5.4e-231 S Uncharacterized protein conserved in bacteria (DUF2325)
DOILEAFA_00846 2.1e-202 nrnB S DHHA1 domain
DOILEAFA_00847 6.3e-50
DOILEAFA_00848 1.6e-137 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DOILEAFA_00849 1.3e-19 S Domain of unknown function (DUF4767)
DOILEAFA_00850 3.6e-54
DOILEAFA_00851 1.4e-116 yrkL S Flavodoxin-like fold
DOILEAFA_00853 4e-65 yeaO S Protein of unknown function, DUF488
DOILEAFA_00854 1.3e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
DOILEAFA_00855 6.8e-204 3.1.3.1 S associated with various cellular activities
DOILEAFA_00856 2.9e-243 S Putative metallopeptidase domain
DOILEAFA_00857 4.6e-48
DOILEAFA_00858 0.0 pepO 3.4.24.71 O Peptidase family M13
DOILEAFA_00859 9.9e-104 K Helix-turn-helix domain
DOILEAFA_00860 2.3e-87 ymdB S Macro domain protein
DOILEAFA_00861 1.6e-197 EGP Major facilitator Superfamily
DOILEAFA_00862 4.9e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DOILEAFA_00863 1.6e-54 K helix_turn_helix, mercury resistance
DOILEAFA_00864 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOILEAFA_00865 3.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
DOILEAFA_00866 0.0 ysaB V FtsX-like permease family
DOILEAFA_00867 4.9e-134 macB2 V ABC transporter, ATP-binding protein
DOILEAFA_00868 7.4e-183 T PhoQ Sensor
DOILEAFA_00869 7.5e-126 K response regulator
DOILEAFA_00870 3.9e-156 ytbE 1.1.1.346 S Aldo keto reductase
DOILEAFA_00871 1.8e-136 pnuC H nicotinamide mononucleotide transporter
DOILEAFA_00872 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOILEAFA_00873 3.9e-204
DOILEAFA_00874 9.1e-53
DOILEAFA_00875 9.1e-36
DOILEAFA_00876 2.4e-92 yxkA S Phosphatidylethanolamine-binding protein
DOILEAFA_00877 8.9e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
DOILEAFA_00878 2.3e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
DOILEAFA_00879 1.7e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DOILEAFA_00880 3.1e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
DOILEAFA_00881 4.5e-180 galR K Transcriptional regulator
DOILEAFA_00882 4.3e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
DOILEAFA_00883 6.8e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DOILEAFA_00884 1.5e-80 K AsnC family
DOILEAFA_00885 3.3e-80 uspA T universal stress protein
DOILEAFA_00886 1.7e-68 ltrA S Bacterial low temperature requirement A protein (LtrA)
DOILEAFA_00887 2.1e-40 ltrA S Bacterial low temperature requirement A protein (LtrA)
DOILEAFA_00888 1.4e-286 lacS G Transporter
DOILEAFA_00889 2.1e-32
DOILEAFA_00890 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DOILEAFA_00891 1.7e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DOILEAFA_00892 5.2e-193 yeaN P Transporter, major facilitator family protein
DOILEAFA_00893 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
DOILEAFA_00894 1.7e-84 nrdI F Belongs to the NrdI family
DOILEAFA_00895 2.1e-241 yhdP S Transporter associated domain
DOILEAFA_00896 3.4e-155 ypdB V (ABC) transporter
DOILEAFA_00897 3e-90 GM epimerase
DOILEAFA_00898 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
DOILEAFA_00899 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
DOILEAFA_00900 4e-133 XK27_07210 6.1.1.6 S B3 4 domain
DOILEAFA_00901 1.8e-172 S AI-2E family transporter
DOILEAFA_00902 1e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
DOILEAFA_00903 1.7e-165
DOILEAFA_00904 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DOILEAFA_00905 5.6e-147 eutJ E Hsp70 protein
DOILEAFA_00906 4.7e-199 K helix_turn_helix, arabinose operon control protein
DOILEAFA_00907 6.2e-42 pduA_4 CQ BMC
DOILEAFA_00908 2.7e-134 pduB E BMC
DOILEAFA_00909 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
DOILEAFA_00910 1.1e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
DOILEAFA_00911 1.1e-76 pduE 4.2.1.28 Q Dehydratase small subunit
DOILEAFA_00912 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
DOILEAFA_00913 6.5e-60 pduH S Dehydratase medium subunit
DOILEAFA_00914 2.8e-73 pduK CQ BMC
DOILEAFA_00915 2.2e-42 pduA_4 CQ BMC
DOILEAFA_00916 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
DOILEAFA_00917 2.7e-88 S Putative propanediol utilisation
DOILEAFA_00918 8.9e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
DOILEAFA_00919 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
DOILEAFA_00920 2.8e-79 pduO S Haem-degrading
DOILEAFA_00921 3.4e-269 pduP 1.2.1.87 C Aldehyde dehydrogenase family
DOILEAFA_00922 4.8e-210 pduQ C Iron-containing alcohol dehydrogenase
DOILEAFA_00923 6.3e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOILEAFA_00924 5.5e-56 pduU E BMC
DOILEAFA_00925 1.4e-147 3.1.3.48 T Pfam:Y_phosphatase3C
DOILEAFA_00926 1.3e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
DOILEAFA_00927 6.7e-80 P Cadmium resistance transporter
DOILEAFA_00928 5.7e-71 eutP E Ethanolamine utilisation - propanediol utilisation
DOILEAFA_00929 3.9e-78 fld C Flavodoxin
DOILEAFA_00930 6.6e-156 XK27_04590 S NADPH-dependent FMN reductase
DOILEAFA_00931 6.3e-102 cobO 2.5.1.17 S Cobalamin adenosyltransferase
DOILEAFA_00932 6.2e-207 cobD 4.1.1.81 E Aminotransferase class I and II
DOILEAFA_00933 1e-262 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
DOILEAFA_00934 3.7e-179 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DOILEAFA_00935 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
DOILEAFA_00936 3.5e-208 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DOILEAFA_00937 9.7e-109 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
DOILEAFA_00938 3.9e-96 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
DOILEAFA_00939 2.9e-134 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
DOILEAFA_00940 5.5e-192 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
DOILEAFA_00941 2.8e-131 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
DOILEAFA_00942 1.1e-133 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
DOILEAFA_00943 4e-259 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
DOILEAFA_00944 2.6e-146 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
DOILEAFA_00945 1.9e-124 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
DOILEAFA_00946 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DOILEAFA_00947 1.9e-52 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DOILEAFA_00948 1.7e-117 cbiQ P Cobalt transport protein
DOILEAFA_00949 1.7e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
DOILEAFA_00950 4.8e-282 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
DOILEAFA_00951 7.9e-79 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
DOILEAFA_00952 1.8e-229 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DOILEAFA_00953 8.5e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
DOILEAFA_00954 1.3e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
DOILEAFA_00955 1.4e-250 hemL 5.4.3.8 H Aminotransferase class-III
DOILEAFA_00956 1.6e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
DOILEAFA_00957 2.2e-134 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DOILEAFA_00958 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
DOILEAFA_00959 5.3e-130 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
DOILEAFA_00960 2.2e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
DOILEAFA_00961 3.1e-60 S Domain of unknown function (DUF4430)
DOILEAFA_00962 1.2e-81 S ECF transporter, substrate-specific component
DOILEAFA_00963 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOILEAFA_00964 1.8e-309 lmrA V ABC transporter, ATP-binding protein
DOILEAFA_00965 0.0 yfiC V ABC transporter
DOILEAFA_00966 7e-283 pipD E Dipeptidase
DOILEAFA_00967 6.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DOILEAFA_00968 4.3e-135 gntR K UbiC transcription regulator-associated domain protein
DOILEAFA_00969 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
DOILEAFA_00970 2.5e-220 yagE E amino acid
DOILEAFA_00971 2e-140 aroD S Serine hydrolase (FSH1)
DOILEAFA_00972 1.1e-242 brnQ U Component of the transport system for branched-chain amino acids
DOILEAFA_00973 1.1e-167 GK ROK family
DOILEAFA_00974 0.0 tetP J elongation factor G
DOILEAFA_00975 8.6e-81 uspA T universal stress protein
DOILEAFA_00976 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
DOILEAFA_00977 7.1e-63
DOILEAFA_00978 5.2e-14
DOILEAFA_00979 3.3e-108
DOILEAFA_00980 4.7e-136 V ABC transporter
DOILEAFA_00981 4.1e-212 EGP Major facilitator Superfamily
DOILEAFA_00982 1.6e-255 G PTS system Galactitol-specific IIC component
DOILEAFA_00983 1.9e-178 1.6.5.5 C Zinc-binding dehydrogenase
DOILEAFA_00984 3.5e-85 K FCD
DOILEAFA_00985 4e-158 S Membrane transport protein
DOILEAFA_00986 3.5e-132 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOILEAFA_00987 7e-161
DOILEAFA_00988 1e-72 K Transcriptional regulator
DOILEAFA_00989 8.2e-190 D Alpha beta
DOILEAFA_00990 2.2e-52 ypaA S Protein of unknown function (DUF1304)
DOILEAFA_00991 0.0 yjcE P Sodium proton antiporter
DOILEAFA_00992 1.6e-52 yvlA
DOILEAFA_00993 4.5e-112 P Cobalt transport protein
DOILEAFA_00994 4.3e-245 cbiO1 S ABC transporter, ATP-binding protein
DOILEAFA_00995 8.7e-96 S ABC-type cobalt transport system, permease component
DOILEAFA_00996 3.3e-133 S membrane transporter protein
DOILEAFA_00997 1.2e-137 IQ KR domain
DOILEAFA_00998 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
DOILEAFA_00999 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
DOILEAFA_01001 3.6e-152 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DOILEAFA_01002 2.1e-115 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DOILEAFA_01003 6.3e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
DOILEAFA_01004 3.8e-249 yagE E amino acid
DOILEAFA_01005 2.6e-85 dps P Belongs to the Dps family
DOILEAFA_01006 0.0 pacL 3.6.3.8 P P-type ATPase
DOILEAFA_01007 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
DOILEAFA_01008 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
DOILEAFA_01009 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DOILEAFA_01010 2.9e-145 potB P ABC transporter permease
DOILEAFA_01011 5.5e-139 potC P ABC transporter permease
DOILEAFA_01012 3.9e-209 potD P ABC transporter
DOILEAFA_01013 6.9e-229
DOILEAFA_01014 1.9e-38 3.6.1.13, 3.6.1.55 F NUDIX domain
DOILEAFA_01015 1e-297 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
DOILEAFA_01016 2.5e-36 copZ P PFAM Heavy metal transport detoxification protein
DOILEAFA_01017 2.4e-98 dps P Belongs to the Dps family
DOILEAFA_01018 4.2e-110 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
DOILEAFA_01019 5.4e-35 L Plasmid pRiA4b ORF-3-like protein
DOILEAFA_01021 0.0 tolA M M26 IgA1-specific Metallo-endopeptidase C-terminal region
DOILEAFA_01022 8.7e-60
DOILEAFA_01023 4.7e-46 sugE U Multidrug resistance protein
DOILEAFA_01024 3e-106 cylB V ABC-2 type transporter
DOILEAFA_01025 4.7e-10 cylB V ABC-2 type transporter
DOILEAFA_01026 3.3e-147 cylA V ABC transporter
DOILEAFA_01027 5.7e-52
DOILEAFA_01028 0.0 XK27_08510 L Type III restriction protein res subunit
DOILEAFA_01029 1.1e-72 S PFAM Archaeal ATPase
DOILEAFA_01030 9.9e-18 S PFAM Archaeal ATPase
DOILEAFA_01031 1.5e-68 S PFAM Archaeal ATPase
DOILEAFA_01032 3.8e-87 3.6.4.12 S PD-(D/E)XK nuclease family transposase
DOILEAFA_01033 1.2e-206 amtB P ammonium transporter
DOILEAFA_01034 4.5e-252 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
DOILEAFA_01035 4.4e-92 S B3 4 domain
DOILEAFA_01036 3.7e-91
DOILEAFA_01037 2.1e-58 K Bacterial regulatory proteins, tetR family
DOILEAFA_01038 1.1e-126 S Alpha/beta hydrolase family
DOILEAFA_01039 1.5e-123 pnb C nitroreductase
DOILEAFA_01040 9.7e-77 ogt 2.1.1.63 L Methyltransferase
DOILEAFA_01041 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
DOILEAFA_01042 7.3e-156 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
DOILEAFA_01043 8e-68 S Protein of unknown function (DUF3021)
DOILEAFA_01044 4.1e-77 K LytTr DNA-binding domain
DOILEAFA_01045 1e-95 K Acetyltransferase (GNAT) family
DOILEAFA_01046 1.8e-21
DOILEAFA_01047 3.2e-201 yhjX P Major Facilitator Superfamily
DOILEAFA_01048 7.6e-121 ybhL S Belongs to the BI1 family
DOILEAFA_01049 5.5e-80 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
DOILEAFA_01050 4.8e-193 S Protein of unknown function (DUF3114)
DOILEAFA_01051 9.1e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
DOILEAFA_01052 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DOILEAFA_01053 6.6e-107 yvdD 3.2.2.10 S Belongs to the LOG family
DOILEAFA_01054 9.1e-62 S Domain of unknown function (DUF4828)
DOILEAFA_01055 1e-190 mocA S Oxidoreductase
DOILEAFA_01056 2.5e-231 yfmL L DEAD DEAH box helicase
DOILEAFA_01058 1.7e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
DOILEAFA_01059 2.5e-56
DOILEAFA_01060 1.9e-74 gtcA S Teichoic acid glycosylation protein
DOILEAFA_01061 6.1e-79 fld C Flavodoxin
DOILEAFA_01062 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
DOILEAFA_01063 1.2e-221 arcT 2.6.1.1 E Aminotransferase
DOILEAFA_01064 1e-257 E Arginine ornithine antiporter
DOILEAFA_01065 4.1e-281 yjeM E Amino Acid
DOILEAFA_01066 1.6e-152 yihY S Belongs to the UPF0761 family
DOILEAFA_01067 6.6e-34 S Protein of unknown function (DUF2922)
DOILEAFA_01068 1.4e-30
DOILEAFA_01069 8.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
DOILEAFA_01070 3e-147 cps1D M Domain of unknown function (DUF4422)
DOILEAFA_01071 3.9e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
DOILEAFA_01072 8.5e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
DOILEAFA_01073 8.9e-85 cps3F
DOILEAFA_01074 2.8e-45 ywqC M biosynthesis protein
DOILEAFA_01075 1.4e-209 glf 5.4.99.9 M UDP-galactopyranose mutase
DOILEAFA_01076 2.3e-241 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
DOILEAFA_01077 3.8e-145 waaB GT4 M Glycosyl transferases group 1
DOILEAFA_01078 9.9e-138 M transferase activity, transferring glycosyl groups
DOILEAFA_01079 2.4e-147 S enterobacterial common antigen metabolic process
DOILEAFA_01080 2.4e-95 acmD M repeat protein
DOILEAFA_01081 9.9e-46 M KxYKxGKxW signal domain protein
DOILEAFA_01082 1.3e-105 M repeat protein
DOILEAFA_01083 1.9e-24
DOILEAFA_01084 4.2e-30 S Acyltransferase family
DOILEAFA_01085 4.7e-50 M NlpC P60 family protein
DOILEAFA_01086 5.7e-57 M Peptidase_C39 like family
DOILEAFA_01087 5e-54 ponA V the current gene model (or a revised gene model) may contain a frame shift
DOILEAFA_01088 9.3e-65 gntR1 K Transcriptional regulator, GntR family
DOILEAFA_01089 3.1e-41 V ABC transporter, ATP-binding protein
DOILEAFA_01090 4.4e-42 V ABC transporter, ATP-binding protein
DOILEAFA_01091 2.1e-115
DOILEAFA_01092 6.6e-97 S TraX protein
DOILEAFA_01093 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
DOILEAFA_01094 7e-99 S Pfam:DUF3816
DOILEAFA_01095 0.0 clpE O Belongs to the ClpA ClpB family
DOILEAFA_01096 2.9e-27
DOILEAFA_01097 2.7e-39 ptsH G phosphocarrier protein HPR
DOILEAFA_01098 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOILEAFA_01099 2.2e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
DOILEAFA_01100 1e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
DOILEAFA_01101 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOILEAFA_01102 2.4e-10 ykuJ S Protein of unknown function (DUF1797)
DOILEAFA_01103 7.7e-205 L Belongs to the 'phage' integrase family
DOILEAFA_01105 2.1e-11
DOILEAFA_01106 1.1e-98 2.3.1.128 K Acetyltransferase (GNAT) domain
DOILEAFA_01107 2.6e-237 lmrB EGP Major facilitator Superfamily
DOILEAFA_01108 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
DOILEAFA_01109 7.6e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DOILEAFA_01110 9.4e-161 sufD O Uncharacterized protein family (UPF0051)
DOILEAFA_01111 1.6e-42 lytE M LysM domain protein
DOILEAFA_01112 0.0 oppD EP Psort location Cytoplasmic, score
DOILEAFA_01113 4.2e-95 lytE M LysM domain protein
DOILEAFA_01114 4.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
DOILEAFA_01115 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DOILEAFA_01116 4.5e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
DOILEAFA_01117 1.2e-152 yeaE S Aldo keto
DOILEAFA_01118 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
DOILEAFA_01119 1.4e-172 L transposase, IS605 OrfB family
DOILEAFA_01120 5.6e-283 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
DOILEAFA_01121 1.5e-79 S Psort location Cytoplasmic, score
DOILEAFA_01122 7.7e-86 S Short repeat of unknown function (DUF308)
DOILEAFA_01123 1e-23
DOILEAFA_01124 4.4e-103 V VanZ like family
DOILEAFA_01125 1.8e-232 cycA E Amino acid permease
DOILEAFA_01126 4.3e-85 perR P Belongs to the Fur family
DOILEAFA_01127 3e-257 EGP Major facilitator Superfamily
DOILEAFA_01128 2.3e-93 tag 3.2.2.20 L glycosylase
DOILEAFA_01129 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DOILEAFA_01130 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOILEAFA_01131 2.4e-40
DOILEAFA_01132 3.8e-256 ytgP S Polysaccharide biosynthesis protein
DOILEAFA_01133 1.2e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DOILEAFA_01134 4.8e-276 pepV 3.5.1.18 E dipeptidase PepV
DOILEAFA_01135 1.9e-86 uspA T Belongs to the universal stress protein A family
DOILEAFA_01136 3.6e-180 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
DOILEAFA_01137 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
DOILEAFA_01138 1.9e-112
DOILEAFA_01139 9e-184 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
DOILEAFA_01140 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOILEAFA_01141 2.1e-32
DOILEAFA_01142 3.2e-110 S CAAX protease self-immunity
DOILEAFA_01143 1.9e-43
DOILEAFA_01145 1.9e-54
DOILEAFA_01146 5.1e-142 S Domain of unknown function DUF1829
DOILEAFA_01147 6.9e-71
DOILEAFA_01148 4.5e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DOILEAFA_01149 7e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
DOILEAFA_01150 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
DOILEAFA_01151 9.4e-231 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DOILEAFA_01152 9.1e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
DOILEAFA_01153 3.9e-215 folP 2.5.1.15 H dihydropteroate synthase
DOILEAFA_01154 1e-43
DOILEAFA_01155 3.3e-40
DOILEAFA_01157 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DOILEAFA_01158 1.6e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DOILEAFA_01159 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DOILEAFA_01160 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
DOILEAFA_01161 2.6e-40 yheA S Belongs to the UPF0342 family
DOILEAFA_01162 1.7e-218 yhaO L Ser Thr phosphatase family protein
DOILEAFA_01163 0.0 L AAA domain
DOILEAFA_01164 8.5e-128 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
DOILEAFA_01166 2.4e-77 hit FG histidine triad
DOILEAFA_01167 1e-136 ecsA V ABC transporter, ATP-binding protein
DOILEAFA_01168 2.3e-218 ecsB U ABC transporter
DOILEAFA_01169 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DOILEAFA_01170 5.1e-184 iolS C Aldo keto reductase
DOILEAFA_01171 1.3e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
DOILEAFA_01172 7.5e-58 ytzB S Small secreted protein
DOILEAFA_01173 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
DOILEAFA_01174 3.2e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOILEAFA_01175 1e-46 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
DOILEAFA_01176 1.6e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
DOILEAFA_01177 3.4e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
DOILEAFA_01178 2.5e-119 ybhL S Belongs to the BI1 family
DOILEAFA_01179 7.5e-118 yoaK S Protein of unknown function (DUF1275)
DOILEAFA_01180 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DOILEAFA_01181 2.2e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
DOILEAFA_01182 1.5e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DOILEAFA_01183 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DOILEAFA_01184 1.8e-208 dnaB L replication initiation and membrane attachment
DOILEAFA_01185 8.1e-171 dnaI L Primosomal protein DnaI
DOILEAFA_01186 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DOILEAFA_01187 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
DOILEAFA_01188 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DOILEAFA_01189 4.8e-96 yqeG S HAD phosphatase, family IIIA
DOILEAFA_01190 5.6e-219 yqeH S Ribosome biogenesis GTPase YqeH
DOILEAFA_01191 1.9e-47 yhbY J RNA-binding protein
DOILEAFA_01192 7.9e-125 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DOILEAFA_01193 3.3e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
DOILEAFA_01194 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DOILEAFA_01195 1.9e-138 yqeM Q Methyltransferase
DOILEAFA_01196 1e-212 ylbM S Belongs to the UPF0348 family
DOILEAFA_01197 2.9e-99 yceD S Uncharacterized ACR, COG1399
DOILEAFA_01198 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DOILEAFA_01199 1.5e-121 K response regulator
DOILEAFA_01200 5.4e-278 arlS 2.7.13.3 T Histidine kinase
DOILEAFA_01201 4.3e-267 yjeM E Amino Acid
DOILEAFA_01202 8.9e-232 V MatE
DOILEAFA_01203 2.5e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DOILEAFA_01204 1.5e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DOILEAFA_01205 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
DOILEAFA_01206 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DOILEAFA_01207 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DOILEAFA_01208 6.7e-59 yodB K Transcriptional regulator, HxlR family
DOILEAFA_01209 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DOILEAFA_01210 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
DOILEAFA_01211 3e-116 rlpA M PFAM NLP P60 protein
DOILEAFA_01212 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
DOILEAFA_01213 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DOILEAFA_01214 7.5e-70 yneR S Belongs to the HesB IscA family
DOILEAFA_01215 0.0 S membrane
DOILEAFA_01216 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
DOILEAFA_01217 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
DOILEAFA_01218 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DOILEAFA_01219 1.6e-112 gluP 3.4.21.105 S Peptidase, S54 family
DOILEAFA_01220 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
DOILEAFA_01221 1.5e-183 glk 2.7.1.2 G Glucokinase
DOILEAFA_01222 1.3e-66 yqhL P Rhodanese-like protein
DOILEAFA_01223 3.2e-20 S Protein of unknown function (DUF3042)
DOILEAFA_01224 3.1e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DOILEAFA_01225 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
DOILEAFA_01226 5.3e-297 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DOILEAFA_01227 3.8e-218 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
DOILEAFA_01228 3.9e-12
DOILEAFA_01229 1.9e-155 P Belongs to the nlpA lipoprotein family
DOILEAFA_01230 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DOILEAFA_01231 1.4e-50 S Iron-sulfur cluster assembly protein
DOILEAFA_01232 1e-151
DOILEAFA_01233 4.1e-184
DOILEAFA_01234 1.9e-89 dut S Protein conserved in bacteria
DOILEAFA_01237 9.8e-112 K Transcriptional regulator
DOILEAFA_01238 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
DOILEAFA_01239 6.2e-54 ysxB J Cysteine protease Prp
DOILEAFA_01240 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
DOILEAFA_01241 8.6e-133 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DOILEAFA_01242 6.6e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DOILEAFA_01243 4.5e-115 J 2'-5' RNA ligase superfamily
DOILEAFA_01244 8.4e-70 yqhY S Asp23 family, cell envelope-related function
DOILEAFA_01245 1.4e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DOILEAFA_01246 1.9e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DOILEAFA_01247 9.3e-221 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOILEAFA_01248 1.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DOILEAFA_01249 1.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOILEAFA_01250 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DOILEAFA_01251 1.1e-77 argR K Regulates arginine biosynthesis genes
DOILEAFA_01252 1.2e-262 recN L May be involved in recombinational repair of damaged DNA
DOILEAFA_01253 1.7e-54
DOILEAFA_01254 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
DOILEAFA_01255 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DOILEAFA_01256 6.2e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DOILEAFA_01257 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DOILEAFA_01258 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DOILEAFA_01259 2.8e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DOILEAFA_01260 2.9e-131 stp 3.1.3.16 T phosphatase
DOILEAFA_01261 0.0 KLT serine threonine protein kinase
DOILEAFA_01262 3.1e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
DOILEAFA_01263 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
DOILEAFA_01264 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
DOILEAFA_01265 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
DOILEAFA_01266 4.7e-58 asp S Asp23 family, cell envelope-related function
DOILEAFA_01267 0.0 yloV S DAK2 domain fusion protein YloV
DOILEAFA_01268 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DOILEAFA_01269 3.6e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
DOILEAFA_01270 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
DOILEAFA_01271 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DOILEAFA_01272 0.0 smc D Required for chromosome condensation and partitioning
DOILEAFA_01273 5.9e-179 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DOILEAFA_01274 1.1e-56 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
DOILEAFA_01275 7.9e-250 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DOILEAFA_01276 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DOILEAFA_01277 4.1e-40 ylqC S Belongs to the UPF0109 family
DOILEAFA_01278 2e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DOILEAFA_01279 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DOILEAFA_01280 1.7e-260 yfnA E amino acid
DOILEAFA_01281 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DOILEAFA_01282 1.8e-209 L Belongs to the 'phage' integrase family
DOILEAFA_01283 4.1e-50
DOILEAFA_01284 3.9e-68 S Domain of unknown function DUF1828
DOILEAFA_01285 8.8e-28
DOILEAFA_01286 6.8e-28 L nuclease
DOILEAFA_01287 3.4e-42
DOILEAFA_01288 4.4e-11
DOILEAFA_01289 7.7e-35
DOILEAFA_01290 3.9e-51 S Mazg nucleotide pyrophosphohydrolase
DOILEAFA_01291 2.5e-160 xth 3.1.11.2 L exodeoxyribonuclease III
DOILEAFA_01292 1.5e-83
DOILEAFA_01293 4.6e-188 lacR K Transcriptional regulator
DOILEAFA_01294 0.0 lacS G Transporter
DOILEAFA_01295 0.0 lacZ 3.2.1.23 G -beta-galactosidase
DOILEAFA_01296 6.5e-179 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
DOILEAFA_01297 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
DOILEAFA_01298 2.6e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
DOILEAFA_01299 2.4e-223 mdtG EGP Major facilitator Superfamily
DOILEAFA_01300 2.6e-168 T Calcineurin-like phosphoesterase superfamily domain
DOILEAFA_01301 9.2e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOILEAFA_01303 2.4e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
DOILEAFA_01304 3.1e-140 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
DOILEAFA_01305 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
DOILEAFA_01306 0.0 trxB2 1.8.1.9 C Thioredoxin domain
DOILEAFA_01307 0.0 M LPXTG-motif cell wall anchor domain protein
DOILEAFA_01308 1.8e-82 M family 8
DOILEAFA_01309 8.5e-149 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
DOILEAFA_01310 1.7e-194 M transferase activity, transferring glycosyl groups
DOILEAFA_01311 7.4e-219 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
DOILEAFA_01312 6.1e-160 asp3 S Accessory Sec secretory system ASP3
DOILEAFA_01313 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOILEAFA_01314 2.9e-226 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
DOILEAFA_01315 7.2e-197 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
DOILEAFA_01317 5.5e-110 dedA S SNARE-like domain protein
DOILEAFA_01318 9.5e-102 S Protein of unknown function (DUF1461)
DOILEAFA_01319 7.2e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
DOILEAFA_01320 9.6e-92 yutD S Protein of unknown function (DUF1027)
DOILEAFA_01321 1.9e-112 S Calcineurin-like phosphoesterase
DOILEAFA_01322 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DOILEAFA_01323 2.5e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
DOILEAFA_01325 1.4e-69
DOILEAFA_01326 2.7e-40
DOILEAFA_01327 5.4e-77 NU general secretion pathway protein
DOILEAFA_01328 7.1e-47 comGC U competence protein ComGC
DOILEAFA_01329 7.1e-184 comGB NU type II secretion system
DOILEAFA_01330 7.9e-185 comGA NU Type II IV secretion system protein
DOILEAFA_01331 3.8e-131 yebC K Transcriptional regulatory protein
DOILEAFA_01332 2.1e-133
DOILEAFA_01333 1.8e-179 ccpA K catabolite control protein A
DOILEAFA_01334 9.4e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
DOILEAFA_01335 1.1e-27
DOILEAFA_01336 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
DOILEAFA_01337 3.4e-147 ykuT M mechanosensitive ion channel
DOILEAFA_01338 1.5e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
DOILEAFA_01339 5.7e-74 ykuL S (CBS) domain
DOILEAFA_01340 6.5e-93 S Phosphoesterase
DOILEAFA_01341 6.6e-102 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DOILEAFA_01342 6.8e-142 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DOILEAFA_01343 4.6e-97 yslB S Protein of unknown function (DUF2507)
DOILEAFA_01344 6.1e-54 trxA O Belongs to the thioredoxin family
DOILEAFA_01345 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
DOILEAFA_01346 1.5e-84 cvpA S Colicin V production protein
DOILEAFA_01347 6.1e-48 yrzB S Belongs to the UPF0473 family
DOILEAFA_01348 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DOILEAFA_01349 4.1e-43 yrzL S Belongs to the UPF0297 family
DOILEAFA_01350 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DOILEAFA_01351 2.4e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
DOILEAFA_01352 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
DOILEAFA_01353 2.8e-31 yajC U Preprotein translocase
DOILEAFA_01354 6.9e-190 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DOILEAFA_01355 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DOILEAFA_01356 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DOILEAFA_01357 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DOILEAFA_01358 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DOILEAFA_01359 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
DOILEAFA_01360 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DOILEAFA_01361 4.9e-232 cinA 3.5.1.42 S Belongs to the CinA family
DOILEAFA_01362 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DOILEAFA_01363 2.5e-141 ymfM S Helix-turn-helix domain
DOILEAFA_01364 3.5e-249 ymfH S Peptidase M16
DOILEAFA_01365 1.7e-229 ymfF S Peptidase M16 inactive domain protein
DOILEAFA_01366 1.3e-159 aatB ET ABC transporter substrate-binding protein
DOILEAFA_01367 3.6e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOILEAFA_01368 3.2e-102 glnP P ABC transporter permease
DOILEAFA_01369 9.6e-92 mreD M rod shape-determining protein MreD
DOILEAFA_01370 5.9e-152 mreC M Involved in formation and maintenance of cell shape
DOILEAFA_01371 1.7e-179 mreB D cell shape determining protein MreB
DOILEAFA_01372 6.8e-121 radC L DNA repair protein
DOILEAFA_01373 1e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
DOILEAFA_01374 9e-231 ndh 1.6.99.3 C NADH dehydrogenase
DOILEAFA_01375 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DOILEAFA_01376 5.1e-309 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
DOILEAFA_01377 4.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
DOILEAFA_01378 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
DOILEAFA_01379 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DOILEAFA_01380 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DOILEAFA_01381 1e-215 iscS2 2.8.1.7 E Aminotransferase class V
DOILEAFA_01382 6.7e-240 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
DOILEAFA_01383 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DOILEAFA_01384 1.7e-290 gadC E amino acid
DOILEAFA_01385 3e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
DOILEAFA_01386 2.1e-285 gadC E amino acid
DOILEAFA_01387 3.8e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
DOILEAFA_01388 1.3e-235 pbuG S permease
DOILEAFA_01389 5.4e-261 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DOILEAFA_01390 1.4e-245 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
DOILEAFA_01391 5.7e-85 L PFAM transposase IS200-family protein
DOILEAFA_01392 1.2e-61 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
DOILEAFA_01393 3e-136 S Belongs to the UPF0246 family
DOILEAFA_01394 1.2e-137 S Membrane
DOILEAFA_01395 8.1e-75 4.4.1.5 E Glyoxalase
DOILEAFA_01396 1.2e-21
DOILEAFA_01397 3.8e-87 yueI S Protein of unknown function (DUF1694)
DOILEAFA_01398 2.6e-236 rarA L recombination factor protein RarA
DOILEAFA_01399 4.4e-46
DOILEAFA_01400 4.3e-83 usp6 T universal stress protein
DOILEAFA_01401 1.2e-205 araR K Transcriptional regulator
DOILEAFA_01402 2.3e-156 ytbE 1.1.1.346 S Aldo keto reductase
DOILEAFA_01403 3.2e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
DOILEAFA_01404 1.1e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
DOILEAFA_01405 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
DOILEAFA_01406 0.0 araB 2.7.1.16 G carbohydrate kinase FGGY
DOILEAFA_01407 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
DOILEAFA_01408 9.6e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
DOILEAFA_01409 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DOILEAFA_01410 1.8e-47 gcvH E glycine cleavage
DOILEAFA_01411 1.1e-220 rodA D Belongs to the SEDS family
DOILEAFA_01412 1e-31 S Protein of unknown function (DUF2969)
DOILEAFA_01413 6.4e-40 yidD S Could be involved in insertion of integral membrane proteins into the membrane
DOILEAFA_01414 1.9e-178 mbl D Cell shape determining protein MreB Mrl
DOILEAFA_01415 5.5e-242 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOILEAFA_01416 1.3e-33 ywzB S Protein of unknown function (DUF1146)
DOILEAFA_01417 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DOILEAFA_01418 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DOILEAFA_01419 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DOILEAFA_01420 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DOILEAFA_01421 6.7e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOILEAFA_01422 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DOILEAFA_01423 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DOILEAFA_01424 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
DOILEAFA_01425 1.3e-232 pyrP F Permease
DOILEAFA_01426 2e-130 yibF S overlaps another CDS with the same product name
DOILEAFA_01427 3.2e-190 yibE S overlaps another CDS with the same product name
DOILEAFA_01428 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DOILEAFA_01429 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DOILEAFA_01430 1.1e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DOILEAFA_01431 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
DOILEAFA_01432 7e-169 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DOILEAFA_01433 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DOILEAFA_01434 1.7e-107 tdk 2.7.1.21 F thymidine kinase
DOILEAFA_01435 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
DOILEAFA_01436 4.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
DOILEAFA_01437 2.1e-223 arcD U Amino acid permease
DOILEAFA_01438 7.5e-261 E Arginine ornithine antiporter
DOILEAFA_01439 2.7e-79 argR K Regulates arginine biosynthesis genes
DOILEAFA_01440 1e-237 arcA 3.5.3.6 E Arginine
DOILEAFA_01441 5.1e-195 ampC V Beta-lactamase
DOILEAFA_01442 1.3e-33
DOILEAFA_01443 0.0 M domain protein
DOILEAFA_01444 7.6e-91
DOILEAFA_01445 2.3e-132 L Belongs to the 'phage' integrase family
DOILEAFA_01447 8.3e-10 K Helix-turn-helix XRE-family like proteins
DOILEAFA_01448 3.1e-13 S Helix-turn-helix domain
DOILEAFA_01449 3e-44 S Phage regulatory protein Rha (Phage_pRha)
DOILEAFA_01452 1.3e-08
DOILEAFA_01455 3.3e-13 L DnaD domain protein
DOILEAFA_01457 7e-71
DOILEAFA_01459 1.5e-64
DOILEAFA_01464 9.4e-71 yjcE P Sodium proton antiporter
DOILEAFA_01465 1.1e-172 yjcE P Sodium proton antiporter
DOILEAFA_01466 3.6e-57
DOILEAFA_01468 6.7e-89
DOILEAFA_01469 0.0 copA 3.6.3.54 P P-type ATPase
DOILEAFA_01470 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DOILEAFA_01471 3.8e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
DOILEAFA_01472 7.7e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
DOILEAFA_01473 1e-162 EG EamA-like transporter family
DOILEAFA_01474 5.6e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
DOILEAFA_01475 5.8e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DOILEAFA_01476 9.5e-155 KT YcbB domain
DOILEAFA_01477 0.0 3.2.1.21 GH3 G hydrolase, family 3
DOILEAFA_01478 1.1e-201 3.2.1.58 G Cellulase (glycosyl hydrolase family 5)
DOILEAFA_01479 1.7e-179 blt G MFS/sugar transport protein
DOILEAFA_01480 3.3e-276 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
DOILEAFA_01481 6e-85 3.2.1.37 GH43 K helix_turn_helix, arabinose operon control protein
DOILEAFA_01482 2.8e-298 xylB 2.7.1.17 G Belongs to the FGGY kinase family
DOILEAFA_01483 2.9e-270 xylA 5.3.1.5 G Belongs to the xylose isomerase family
DOILEAFA_01484 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
DOILEAFA_01485 9.7e-237 xynP G MFS/sugar transport protein
DOILEAFA_01486 3.1e-135 xylR GK ROK family
DOILEAFA_01487 0.0 3.2.1.55 GH51 G Right handed beta helix region
DOILEAFA_01488 1.6e-290 xynT G MFS/sugar transport protein
DOILEAFA_01489 9.5e-172 rhaS2 K Transcriptional regulator, AraC family
DOILEAFA_01490 6.2e-260 xylT EGP Major facilitator Superfamily
DOILEAFA_01492 2.5e-217 xylR GK ROK family
DOILEAFA_01493 1.3e-28
DOILEAFA_01494 1.3e-262 pgi 5.3.1.9 G Belongs to the GPI family
DOILEAFA_01495 2.9e-100 lacA 2.3.1.79 S Transferase hexapeptide repeat
DOILEAFA_01496 3.4e-155 glcU U sugar transport
DOILEAFA_01497 2.4e-273 yclK 2.7.13.3 T Histidine kinase
DOILEAFA_01498 5.1e-133 K response regulator
DOILEAFA_01500 2.8e-79 lytE M Lysin motif
DOILEAFA_01501 7.5e-149 XK27_02985 S Cof-like hydrolase
DOILEAFA_01502 2.3e-81 K Transcriptional regulator
DOILEAFA_01503 0.0 oatA I Acyltransferase
DOILEAFA_01504 8.7e-53
DOILEAFA_01505 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DOILEAFA_01506 1.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DOILEAFA_01507 2e-126 ybbR S YbbR-like protein
DOILEAFA_01508 1.1e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
DOILEAFA_01509 4.8e-249 fucP G Major Facilitator Superfamily
DOILEAFA_01510 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
DOILEAFA_01511 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DOILEAFA_01512 3.6e-168 murB 1.3.1.98 M Cell wall formation
DOILEAFA_01513 2.7e-102 dnaQ 2.7.7.7 L DNA polymerase III
DOILEAFA_01514 6.8e-77 S PAS domain
DOILEAFA_01515 3e-87 K Acetyltransferase (GNAT) domain
DOILEAFA_01516 2.2e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
DOILEAFA_01517 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DOILEAFA_01518 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DOILEAFA_01519 3.7e-105 yxjI
DOILEAFA_01520 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DOILEAFA_01521 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
DOILEAFA_01522 6.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
DOILEAFA_01523 1.8e-34 secG U Preprotein translocase
DOILEAFA_01524 2.1e-293 clcA P chloride
DOILEAFA_01525 7.1e-248 yifK E Amino acid permease
DOILEAFA_01526 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DOILEAFA_01527 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOILEAFA_01528 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
DOILEAFA_01529 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DOILEAFA_01531 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DOILEAFA_01532 2.6e-242 glpT G Major Facilitator Superfamily
DOILEAFA_01533 8.8e-15
DOILEAFA_01535 3.4e-169 whiA K May be required for sporulation
DOILEAFA_01536 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
DOILEAFA_01537 1.1e-161 rapZ S Displays ATPase and GTPase activities
DOILEAFA_01538 2.4e-245 steT E amino acid
DOILEAFA_01539 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DOILEAFA_01540 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DOILEAFA_01541 1.5e-13
DOILEAFA_01542 1.9e-115 yfbR S HD containing hydrolase-like enzyme
DOILEAFA_01543 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
DOILEAFA_01544 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
DOILEAFA_01545 1.2e-160 aatB ET PFAM extracellular solute-binding protein, family 3
DOILEAFA_01546 1.2e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
DOILEAFA_01547 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DOILEAFA_01548 2.6e-157 lutA C Cysteine-rich domain
DOILEAFA_01549 2.6e-288 lutB C 4Fe-4S dicluster domain
DOILEAFA_01550 3.5e-137 yrjD S LUD domain
DOILEAFA_01551 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
DOILEAFA_01552 1e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
DOILEAFA_01553 1.5e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DOILEAFA_01554 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DOILEAFA_01555 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DOILEAFA_01556 2.4e-32 KT PspC domain protein
DOILEAFA_01557 3.3e-186 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DOILEAFA_01558 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DOILEAFA_01559 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DOILEAFA_01560 5.5e-113 comFC S Competence protein
DOILEAFA_01561 3.2e-253 comFA L Helicase C-terminal domain protein
DOILEAFA_01562 5e-108 yvyE 3.4.13.9 S YigZ family
DOILEAFA_01563 1.7e-24 K transcriptional regulator
DOILEAFA_01564 6e-40 C nitroreductase
DOILEAFA_01565 2.8e-74 EGP Major facilitator Superfamily
DOILEAFA_01566 2.1e-121 EGP Major facilitator Superfamily
DOILEAFA_01567 1.1e-66 rmaI K Transcriptional regulator
DOILEAFA_01568 2.7e-39
DOILEAFA_01569 0.0 ydaO E amino acid
DOILEAFA_01570 4.8e-304 ybeC E amino acid
DOILEAFA_01571 3.2e-78 S Aminoacyl-tRNA editing domain
DOILEAFA_01572 5.5e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DOILEAFA_01573 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DOILEAFA_01575 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
DOILEAFA_01576 0.0 uup S ABC transporter, ATP-binding protein
DOILEAFA_01577 7.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DOILEAFA_01578 7.7e-227 mtnE 2.6.1.83 E Aminotransferase
DOILEAFA_01579 1e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
DOILEAFA_01580 6.4e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DOILEAFA_01581 6.9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DOILEAFA_01582 9.8e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DOILEAFA_01583 4.4e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DOILEAFA_01584 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
DOILEAFA_01585 9.5e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
DOILEAFA_01586 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DOILEAFA_01587 8.1e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
DOILEAFA_01588 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DOILEAFA_01589 3.7e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
DOILEAFA_01590 1.1e-237 L Transposase
DOILEAFA_01591 6.1e-143 fhaB M Rib/alpha-like repeat
DOILEAFA_01592 0.0 infB UW LPXTG-motif cell wall anchor domain protein
DOILEAFA_01593 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DOILEAFA_01594 1.5e-152
DOILEAFA_01595 5.1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DOILEAFA_01596 6.7e-245 purD 6.3.4.13 F Belongs to the GARS family
DOILEAFA_01597 3.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DOILEAFA_01598 4.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DOILEAFA_01599 2.8e-196 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DOILEAFA_01600 4.6e-274 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DOILEAFA_01601 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOILEAFA_01602 5.2e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOILEAFA_01603 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DOILEAFA_01604 1.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DOILEAFA_01605 5.2e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DOILEAFA_01606 6.2e-213 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DOILEAFA_01607 1.9e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DOILEAFA_01608 3.7e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
DOILEAFA_01609 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
DOILEAFA_01610 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
DOILEAFA_01611 4.7e-172 K AI-2E family transporter
DOILEAFA_01612 7.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
DOILEAFA_01613 3.7e-114 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
DOILEAFA_01614 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DOILEAFA_01615 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
DOILEAFA_01616 2.8e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DOILEAFA_01617 8.1e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DOILEAFA_01618 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DOILEAFA_01619 1.1e-237 L Transposase
DOILEAFA_01620 2.2e-57
DOILEAFA_01622 3.6e-138 mltD CBM50 M NlpC P60 family protein
DOILEAFA_01623 5.7e-29
DOILEAFA_01624 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
DOILEAFA_01625 9.8e-32 ykzG S Belongs to the UPF0356 family
DOILEAFA_01626 3.6e-82
DOILEAFA_01627 1.8e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DOILEAFA_01628 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
DOILEAFA_01629 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
DOILEAFA_01630 6e-228 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
DOILEAFA_01631 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
DOILEAFA_01632 5.1e-47 yktA S Belongs to the UPF0223 family
DOILEAFA_01633 4.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
DOILEAFA_01634 0.0 typA T GTP-binding protein TypA
DOILEAFA_01635 4.5e-222 ftsW D Belongs to the SEDS family
DOILEAFA_01636 2e-43 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
DOILEAFA_01637 7.2e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
DOILEAFA_01638 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DOILEAFA_01639 1e-198 ylbL T Belongs to the peptidase S16 family
DOILEAFA_01640 6.4e-79 comEA L Competence protein ComEA
DOILEAFA_01641 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
DOILEAFA_01642 0.0 comEC S Competence protein ComEC
DOILEAFA_01643 1.8e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
DOILEAFA_01644 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
DOILEAFA_01645 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DOILEAFA_01646 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOILEAFA_01647 9.3e-164 S Tetratricopeptide repeat
DOILEAFA_01648 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DOILEAFA_01649 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DOILEAFA_01650 8.1e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DOILEAFA_01651 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
DOILEAFA_01652 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
DOILEAFA_01653 4.9e-08
DOILEAFA_01654 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DOILEAFA_01655 6.7e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DOILEAFA_01656 1.1e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
DOILEAFA_01657 3.2e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DOILEAFA_01658 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
DOILEAFA_01659 7.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DOILEAFA_01660 2.5e-88
DOILEAFA_01662 3.5e-128 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DOILEAFA_01663 4.7e-213 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
DOILEAFA_01664 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DOILEAFA_01665 1.3e-35 ynzC S UPF0291 protein
DOILEAFA_01666 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
DOILEAFA_01667 2.7e-117 plsC 2.3.1.51 I Acyltransferase
DOILEAFA_01668 2.4e-141 yabB 2.1.1.223 L Methyltransferase small domain
DOILEAFA_01669 5.4e-49 yazA L GIY-YIG catalytic domain protein
DOILEAFA_01670 8.3e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOILEAFA_01671 3.5e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
DOILEAFA_01672 1.6e-152 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DOILEAFA_01673 1.7e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DOILEAFA_01674 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DOILEAFA_01675 6e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DOILEAFA_01676 4.4e-138 cdsA 2.7.7.41 I Belongs to the CDS family
DOILEAFA_01677 1.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
DOILEAFA_01678 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DOILEAFA_01679 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DOILEAFA_01680 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
DOILEAFA_01681 1e-215 nusA K Participates in both transcription termination and antitermination
DOILEAFA_01682 1e-44 ylxR K Protein of unknown function (DUF448)
DOILEAFA_01683 3.8e-48 ylxQ J ribosomal protein
DOILEAFA_01684 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DOILEAFA_01685 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DOILEAFA_01686 5.2e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DOILEAFA_01687 3.8e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
DOILEAFA_01688 2e-64
DOILEAFA_01689 1.8e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DOILEAFA_01690 5.6e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DOILEAFA_01691 0.0 dnaK O Heat shock 70 kDa protein
DOILEAFA_01692 1.9e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DOILEAFA_01693 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DOILEAFA_01694 6.6e-199 S OPT oligopeptide transporter protein
DOILEAFA_01695 1.7e-23 S Coenzyme PQQ synthesis protein D (PqqD)
DOILEAFA_01696 1.3e-276 pipD E Dipeptidase
DOILEAFA_01697 3.1e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
DOILEAFA_01699 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
DOILEAFA_01701 2.8e-57
DOILEAFA_01702 4.8e-179 prmA J Ribosomal protein L11 methyltransferase
DOILEAFA_01703 9.3e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DOILEAFA_01704 1.2e-52
DOILEAFA_01705 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DOILEAFA_01706 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DOILEAFA_01707 1.8e-169 yniA G Phosphotransferase enzyme family
DOILEAFA_01708 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
DOILEAFA_01709 1.1e-237 L Transposase
DOILEAFA_01710 7e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DOILEAFA_01711 3.8e-70 L PFAM Integrase catalytic region
DOILEAFA_01712 9.3e-20 L transposase activity
DOILEAFA_01713 4.1e-15 L Recombinase zinc beta ribbon domain
DOILEAFA_01714 2.1e-95 L Recombinase zinc beta ribbon domain
DOILEAFA_01715 2e-144 L Recombinase zinc beta ribbon domain
DOILEAFA_01716 8.7e-279 L Recombinase
DOILEAFA_01718 3e-173 S Domain of unknown function (DUF389)
DOILEAFA_01719 4.5e-83 EGP Sugar (and other) transporter
DOILEAFA_01720 4.3e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DOILEAFA_01721 6.7e-187 yegS 2.7.1.107 G Lipid kinase
DOILEAFA_01722 9.1e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOILEAFA_01723 5.9e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DOILEAFA_01724 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DOILEAFA_01725 1.2e-202 camS S sex pheromone
DOILEAFA_01726 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DOILEAFA_01727 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
DOILEAFA_01728 3.6e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DOILEAFA_01729 4.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DOILEAFA_01730 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
DOILEAFA_01731 9.4e-141 IQ reductase
DOILEAFA_01732 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
DOILEAFA_01733 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DOILEAFA_01734 9.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DOILEAFA_01735 2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOILEAFA_01736 5.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOILEAFA_01737 3.3e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DOILEAFA_01738 1.1e-62 rplQ J Ribosomal protein L17
DOILEAFA_01739 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOILEAFA_01740 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DOILEAFA_01741 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DOILEAFA_01742 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DOILEAFA_01743 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DOILEAFA_01744 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DOILEAFA_01745 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DOILEAFA_01746 8.9e-64 rplO J Binds to the 23S rRNA
DOILEAFA_01747 2.9e-24 rpmD J Ribosomal protein L30
DOILEAFA_01748 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DOILEAFA_01749 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DOILEAFA_01750 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DOILEAFA_01751 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DOILEAFA_01752 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DOILEAFA_01753 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DOILEAFA_01754 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DOILEAFA_01755 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DOILEAFA_01756 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DOILEAFA_01757 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
DOILEAFA_01758 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DOILEAFA_01759 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DOILEAFA_01760 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DOILEAFA_01761 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DOILEAFA_01762 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DOILEAFA_01763 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DOILEAFA_01764 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
DOILEAFA_01765 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DOILEAFA_01766 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
DOILEAFA_01767 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DOILEAFA_01768 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DOILEAFA_01769 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DOILEAFA_01770 3.4e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DOILEAFA_01771 2.4e-204 ykiI
DOILEAFA_01772 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOILEAFA_01773 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DOILEAFA_01774 1e-110 K Bacterial regulatory proteins, tetR family
DOILEAFA_01775 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DOILEAFA_01776 3.4e-77 ctsR K Belongs to the CtsR family
DOILEAFA_01777 3.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
DOILEAFA_01778 2.6e-180 S Hydrolases of the alpha beta superfamily
DOILEAFA_01779 2.3e-11
DOILEAFA_01785 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
DOILEAFA_01786 2.3e-276 lysP E amino acid
DOILEAFA_01787 6.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
DOILEAFA_01788 2.3e-119 lssY 3.6.1.27 I phosphatase
DOILEAFA_01789 2.1e-82 S Threonine/Serine exporter, ThrE
DOILEAFA_01790 8.1e-129 thrE S Putative threonine/serine exporter
DOILEAFA_01791 1e-30 cspC K Cold shock protein
DOILEAFA_01792 2.4e-124 sirR K iron dependent repressor
DOILEAFA_01793 9.1e-167 czcD P cation diffusion facilitator family transporter
DOILEAFA_01794 2.9e-117 S membrane
DOILEAFA_01795 4.9e-109 S VIT family
DOILEAFA_01796 2.7e-82 usp1 T Belongs to the universal stress protein A family
DOILEAFA_01797 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
DOILEAFA_01798 2.6e-152 glnH ET ABC transporter
DOILEAFA_01799 3.2e-110 gluC P ABC transporter permease
DOILEAFA_01800 1.4e-108 glnP P ABC transporter permease
DOILEAFA_01801 3.5e-219 S CAAX protease self-immunity
DOILEAFA_01802 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DOILEAFA_01803 1.3e-54
DOILEAFA_01804 3.4e-74 merR K MerR HTH family regulatory protein
DOILEAFA_01805 2e-267 lmrB EGP Major facilitator Superfamily
DOILEAFA_01806 2.3e-117 S Domain of unknown function (DUF4811)
DOILEAFA_01807 1.2e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DOILEAFA_01809 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DOILEAFA_01810 1.5e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
DOILEAFA_01811 6.1e-185 I Alpha beta
DOILEAFA_01812 2.6e-275 emrY EGP Major facilitator Superfamily
DOILEAFA_01813 3.3e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
DOILEAFA_01814 9.4e-253 yjjP S Putative threonine/serine exporter
DOILEAFA_01815 3.9e-159 mleR K LysR family
DOILEAFA_01816 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
DOILEAFA_01817 3.4e-266 frdC 1.3.5.4 C FAD binding domain
DOILEAFA_01818 2.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
DOILEAFA_01819 1.1e-303 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
DOILEAFA_01820 1.3e-157 mleR K LysR family
DOILEAFA_01821 1.7e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DOILEAFA_01822 2.5e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
DOILEAFA_01823 3.4e-299 L PFAM plasmid pRiA4b ORF-3 family protein
DOILEAFA_01824 4.2e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
DOILEAFA_01827 5.8e-22
DOILEAFA_01828 2e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
DOILEAFA_01829 6.7e-75
DOILEAFA_01830 2.5e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
DOILEAFA_01831 7.7e-130 ponA V Beta-lactamase enzyme family
DOILEAFA_01832 6.5e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
DOILEAFA_01833 1.4e-215 uhpT EGP Major facilitator Superfamily
DOILEAFA_01834 4.3e-258 ytjP 3.5.1.18 E Dipeptidase
DOILEAFA_01835 3.7e-274 arcD S C4-dicarboxylate anaerobic carrier
DOILEAFA_01836 8.1e-179 yfeX P Peroxidase
DOILEAFA_01837 4.1e-169 lsa S ABC transporter
DOILEAFA_01838 3e-133 I alpha/beta hydrolase fold
DOILEAFA_01839 4.7e-180 MA20_14895 S Conserved hypothetical protein 698
DOILEAFA_01840 3.8e-96 S NADPH-dependent FMN reductase
DOILEAFA_01841 3.5e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
DOILEAFA_01842 2.1e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
DOILEAFA_01843 1.1e-231 mntH P H( )-stimulated, divalent metal cation uptake system
DOILEAFA_01844 3.1e-43 agrA K LytTr DNA-binding domain
DOILEAFA_01847 1.8e-11
DOILEAFA_01849 4.3e-07 S Domain of unknown function (DUF4767)
DOILEAFA_01850 3.2e-79 Q Methyltransferase
DOILEAFA_01851 6.9e-116 ktrA P domain protein
DOILEAFA_01852 1e-238 ktrB P Potassium uptake protein
DOILEAFA_01853 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
DOILEAFA_01854 8.1e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
DOILEAFA_01855 4.4e-219 G Glycosyl hydrolases family 8
DOILEAFA_01856 1.9e-242 ydaM M Glycosyl transferase
DOILEAFA_01857 1.2e-136
DOILEAFA_01858 6.6e-125 phoU P Plays a role in the regulation of phosphate uptake
DOILEAFA_01859 1.4e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DOILEAFA_01860 9.4e-153 pstA P Phosphate transport system permease protein PstA
DOILEAFA_01861 3.3e-153 pstC P probably responsible for the translocation of the substrate across the membrane
DOILEAFA_01862 2.8e-157 pstS P Phosphate
DOILEAFA_01863 2.1e-131 K Transcriptional regulatory protein, C-terminal domain protein
DOILEAFA_01864 8.6e-136 cbiO P ABC transporter
DOILEAFA_01865 3.8e-135 P Cobalt transport protein
DOILEAFA_01866 1e-182 nikMN P PDGLE domain
DOILEAFA_01867 7.6e-73 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOILEAFA_01868 4.9e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DOILEAFA_01869 2e-160 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DOILEAFA_01870 3.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DOILEAFA_01871 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
DOILEAFA_01872 2.5e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DOILEAFA_01873 0.0 ureC 3.5.1.5 E Amidohydrolase family
DOILEAFA_01874 2.9e-63 ureB 3.5.1.5 E Urease beta subunit
DOILEAFA_01875 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
DOILEAFA_01876 2.5e-97 ureI S AmiS/UreI family transporter
DOILEAFA_01877 4e-223 P ammonium transporter
DOILEAFA_01878 1.7e-16 K Transcriptional regulator, HxlR family
DOILEAFA_01879 3.3e-186
DOILEAFA_01880 4.4e-97 2.3.1.128 K acetyltransferase
DOILEAFA_01881 1.1e-112 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOILEAFA_01882 1.6e-93 lysR5 K LysR substrate binding domain
DOILEAFA_01883 3.7e-142 manA 5.3.1.8 G mannose-6-phosphate isomerase
DOILEAFA_01884 8.9e-159 K LysR substrate binding domain
DOILEAFA_01885 6.3e-207 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
DOILEAFA_01886 2e-64 L Transposase IS200 like
DOILEAFA_01887 1.1e-182 L transposase, IS605 OrfB family
DOILEAFA_01888 7.4e-52 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOILEAFA_01889 4e-163
DOILEAFA_01890 1.9e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DOILEAFA_01891 1.4e-182 S Phosphotransferase system, EIIC
DOILEAFA_01892 0.0 UW LPXTG-motif cell wall anchor domain protein
DOILEAFA_01893 0.0 UW LPXTG-motif cell wall anchor domain protein
DOILEAFA_01894 0.0 UW LPXTG-motif cell wall anchor domain protein
DOILEAFA_01896 9.5e-158 metQ_4 P Belongs to the nlpA lipoprotein family
DOILEAFA_01897 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DOILEAFA_01898 3.8e-125 O Zinc-dependent metalloprotease
DOILEAFA_01899 1.2e-114 S Membrane
DOILEAFA_01900 3.3e-197 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
DOILEAFA_01901 1.9e-77 S Domain of unknown function (DUF4767)
DOILEAFA_01902 4.3e-13
DOILEAFA_01903 1.5e-203 cytX U Belongs to the purine-cytosine permease (2.A.39) family
DOILEAFA_01904 1.2e-94 wecD3 K PFAM GCN5-related N-acetyltransferase
DOILEAFA_01905 1.2e-79
DOILEAFA_01906 3.6e-114 M Lysin motif
DOILEAFA_01907 6.5e-194 EGP Major facilitator Superfamily
DOILEAFA_01908 2.9e-35 D Antitoxin component of a toxin-antitoxin (TA) module
DOILEAFA_01909 8.3e-54 S ParE toxin of type II toxin-antitoxin system, parDE
DOILEAFA_01910 6e-100 ywlG S Belongs to the UPF0340 family
DOILEAFA_01911 2.1e-100 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
DOILEAFA_01912 6.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
DOILEAFA_01913 2.4e-138 pnuC H nicotinamide mononucleotide transporter
DOILEAFA_01914 1e-128 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
DOILEAFA_01915 6.9e-100 crp_2 K Cyclic nucleotide-binding domain
DOILEAFA_01916 2.6e-128 S PFAM Archaeal ATPase
DOILEAFA_01917 7.8e-160 spoU 2.1.1.185 J Methyltransferase
DOILEAFA_01918 1.6e-222 oxlT P Major Facilitator Superfamily
DOILEAFA_01919 3.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DOILEAFA_01921 5.4e-220 S cog cog1373
DOILEAFA_01922 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
DOILEAFA_01923 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
DOILEAFA_01924 9.2e-161 EG EamA-like transporter family
DOILEAFA_01925 4.5e-255 nox C NADH oxidase
DOILEAFA_01926 8.7e-243 nox C NADH oxidase
DOILEAFA_01927 0.0 helD 3.6.4.12 L DNA helicase
DOILEAFA_01928 8.8e-116 dedA S SNARE associated Golgi protein
DOILEAFA_01929 5e-127 3.1.3.73 G phosphoglycerate mutase
DOILEAFA_01930 6.8e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DOILEAFA_01931 1.4e-10
DOILEAFA_01932 2e-31 S Transglycosylase associated protein
DOILEAFA_01934 1.4e-181 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DOILEAFA_01935 1.5e-220 V domain protein
DOILEAFA_01936 1.6e-94 K Transcriptional regulator (TetR family)
DOILEAFA_01937 4.4e-39 pspC KT PspC domain protein
DOILEAFA_01938 1.4e-150
DOILEAFA_01939 3.1e-17 3.2.1.14 GH18
DOILEAFA_01940 1.5e-82 zur P Belongs to the Fur family
DOILEAFA_01941 5.8e-103 gmk2 2.7.4.8 F Guanylate kinase
DOILEAFA_01942 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
DOILEAFA_01943 3e-254 yfnA E Amino Acid
DOILEAFA_01944 1.4e-229 EGP Sugar (and other) transporter
DOILEAFA_01945 8.2e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DOILEAFA_01946 2.9e-231 brpA K Cell envelope-like function transcriptional attenuator common domain protein
DOILEAFA_01947 3.2e-164 S Psort location CytoplasmicMembrane, score
DOILEAFA_01948 1.5e-160 yueF S AI-2E family transporter
DOILEAFA_01949 4.9e-44 S dextransucrase activity
DOILEAFA_01950 4.7e-42 cotH M CotH kinase protein
DOILEAFA_01951 9e-165 ykoT GT2 M Glycosyl transferase family 2
DOILEAFA_01952 2.6e-34
DOILEAFA_01953 1.5e-105 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DOILEAFA_01954 3.3e-98 M Glycosyltransferase like family 2
DOILEAFA_01955 6.8e-36 M Peptidase_C39 like family
DOILEAFA_01956 2.8e-221 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
DOILEAFA_01957 8.9e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
DOILEAFA_01958 3.6e-129 IQ Dehydrogenase reductase
DOILEAFA_01959 2.9e-37
DOILEAFA_01960 7.5e-115 ywnB S NAD(P)H-binding
DOILEAFA_01961 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
DOILEAFA_01962 4e-254 nhaC C Na H antiporter NhaC
DOILEAFA_01963 1.6e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DOILEAFA_01965 1.5e-97 ydeN S Serine hydrolase
DOILEAFA_01966 4.5e-62 psiE S Phosphate-starvation-inducible E
DOILEAFA_01967 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOILEAFA_01969 4.6e-174 S Aldo keto reductase
DOILEAFA_01970 3.8e-82 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
DOILEAFA_01971 0.0 L Helicase C-terminal domain protein
DOILEAFA_01973 1.6e-244 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
DOILEAFA_01974 1.1e-37 S Sugar efflux transporter for intercellular exchange
DOILEAFA_01975 1.2e-126
DOILEAFA_01976 5.8e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
DOILEAFA_01977 0.0 cadA P P-type ATPase
DOILEAFA_01978 5.9e-219 5.4.2.7 G Metalloenzyme superfamily
DOILEAFA_01979 1e-07
DOILEAFA_01980 1e-156 1.6.5.2 GM NAD(P)H-binding
DOILEAFA_01981 5.3e-75 K Transcriptional regulator
DOILEAFA_01982 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
DOILEAFA_01983 1.8e-108 proWZ P ABC transporter permease
DOILEAFA_01984 4.2e-141 proV E ABC transporter, ATP-binding protein
DOILEAFA_01985 4.3e-99 proW P ABC transporter, permease protein
DOILEAFA_01986 2e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
DOILEAFA_01987 5.4e-253 clcA P chloride
DOILEAFA_01988 9.8e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
DOILEAFA_01989 3.1e-103 metI P ABC transporter permease
DOILEAFA_01990 1.6e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DOILEAFA_01991 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
DOILEAFA_01992 6.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DOILEAFA_01993 1.3e-221 norA EGP Major facilitator Superfamily
DOILEAFA_01994 3.3e-43 1.3.5.4 S FMN binding
DOILEAFA_01995 8.4e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DOILEAFA_01996 3.4e-264 yfnA E amino acid
DOILEAFA_01997 5e-254 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DOILEAFA_01999 1.4e-57 K Helix-turn-helix domain
DOILEAFA_02000 4.2e-127 rpfI 3.1.3.48 D nuclear chromosome segregation
DOILEAFA_02006 1.1e-175 repB EP Plasmid replication protein
DOILEAFA_02007 1.2e-233 L Belongs to the 'phage' integrase family
DOILEAFA_02008 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
DOILEAFA_02009 0.0 helD 3.6.4.12 L DNA helicase
DOILEAFA_02010 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
DOILEAFA_02011 2.3e-181 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
DOILEAFA_02012 1.2e-188 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DOILEAFA_02013 1.8e-162 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
DOILEAFA_02014 1.7e-219 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
DOILEAFA_02015 3.5e-177
DOILEAFA_02016 8e-131 cobB K SIR2 family
DOILEAFA_02018 7.4e-163 yunF F Protein of unknown function DUF72
DOILEAFA_02019 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DOILEAFA_02020 4.9e-156 tatD L hydrolase, TatD family
DOILEAFA_02021 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
DOILEAFA_02022 3.4e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DOILEAFA_02023 6.8e-37 veg S Biofilm formation stimulator VEG
DOILEAFA_02024 9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DOILEAFA_02025 3.4e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
DOILEAFA_02026 1.2e-120 fhuC P ABC transporter
DOILEAFA_02027 7.2e-128 znuB U ABC 3 transport family
DOILEAFA_02028 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
DOILEAFA_02029 3.7e-241 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DOILEAFA_02030 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DOILEAFA_02031 8.9e-48
DOILEAFA_02032 2.6e-149 yxeH S hydrolase
DOILEAFA_02033 2.2e-270 ywfO S HD domain protein
DOILEAFA_02034 2.1e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
DOILEAFA_02035 4.6e-67 ywiB S Domain of unknown function (DUF1934)
DOILEAFA_02036 8.6e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
DOILEAFA_02037 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DOILEAFA_02038 5.2e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DOILEAFA_02039 4.6e-41 rpmE2 J Ribosomal protein L31
DOILEAFA_02040 1.6e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
DOILEAFA_02041 3.1e-164 S Alpha/beta hydrolase of unknown function (DUF915)
DOILEAFA_02042 3.3e-124 srtA 3.4.22.70 M sortase family
DOILEAFA_02043 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
DOILEAFA_02044 5.2e-158 3.2.1.55 GH51 G Right handed beta helix region
DOILEAFA_02045 1.2e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DOILEAFA_02046 6.4e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
DOILEAFA_02047 3.9e-119 pgm3 G Belongs to the phosphoglycerate mutase family
DOILEAFA_02048 1.8e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DOILEAFA_02049 1.6e-92 lemA S LemA family
DOILEAFA_02050 1.5e-158 htpX O Belongs to the peptidase M48B family
DOILEAFA_02051 6e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DOILEAFA_02052 9e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
DOILEAFA_02053 0.0 sprD D Domain of Unknown Function (DUF1542)
DOILEAFA_02054 9e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
DOILEAFA_02055 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
DOILEAFA_02056 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOILEAFA_02057 1.3e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
DOILEAFA_02058 3.8e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
DOILEAFA_02060 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DOILEAFA_02061 9e-209 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DOILEAFA_02062 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
DOILEAFA_02063 9.8e-250 U Belongs to the purine-cytosine permease (2.A.39) family
DOILEAFA_02064 6.1e-243 codA 3.5.4.1 F cytosine deaminase
DOILEAFA_02065 3.1e-147 tesE Q hydratase
DOILEAFA_02066 8.1e-114 S (CBS) domain
DOILEAFA_02067 4.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DOILEAFA_02068 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DOILEAFA_02069 2.1e-39 yabO J S4 domain protein
DOILEAFA_02070 5.6e-56 divIC D Septum formation initiator
DOILEAFA_02071 9.8e-67 yabR J RNA binding
DOILEAFA_02072 9.4e-264 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DOILEAFA_02073 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DOILEAFA_02074 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DOILEAFA_02075 8e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DOILEAFA_02076 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DOILEAFA_02077 1e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DOILEAFA_02078 8.3e-88
DOILEAFA_02079 2.7e-57 L Probable transposase
DOILEAFA_02080 4.8e-23 higA K Addiction module antidote protein, HigA
DOILEAFA_02086 2.6e-34 S Uncharacterized protein conserved in bacteria (DUF2325)
DOILEAFA_02087 6.9e-73 XK27_00160 S Domain of unknown function (DUF5052)
DOILEAFA_02109 3.1e-178 XK27_11280 S Psort location CytoplasmicMembrane, score
DOILEAFA_02110 1.6e-13 XK27_11280 S Psort location CytoplasmicMembrane, score
DOILEAFA_02114 2.2e-15
DOILEAFA_02123 2.4e-56 L Lactococcus lactis RepB C-terminus
DOILEAFA_02124 2.1e-08
DOILEAFA_02125 2e-174 L transposase, IS605 OrfB family
DOILEAFA_02126 3.8e-38 L Transposase IS200 like
DOILEAFA_02127 1.6e-20
DOILEAFA_02128 8.5e-33 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
DOILEAFA_02129 4.3e-13 K prlF antitoxin for toxin YhaV_toxin
DOILEAFA_02132 3.6e-08
DOILEAFA_02133 1.7e-40 S HicB_like antitoxin of bacterial toxin-antitoxin system
DOILEAFA_02135 1.2e-07
DOILEAFA_02142 8.9e-12
DOILEAFA_02143 9.6e-66 Q DNA (cytosine-5-)-methyltransferase activity
DOILEAFA_02149 1.9e-238 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)