ORF_ID e_value Gene_name EC_number CAZy COGs Description
HGEILGHP_00001 1.7e-54 K Transcriptional regulator, ArsR family
HGEILGHP_00002 1.1e-93 P Cadmium resistance transporter
HGEILGHP_00003 8.2e-137 XK27_08845 S ABC transporter, ATP-binding protein
HGEILGHP_00004 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HGEILGHP_00005 1.7e-182 ABC-SBP S ABC transporter
HGEILGHP_00007 1.2e-07
HGEILGHP_00008 1.4e-105 S Protein of unknown function (DUF3278)
HGEILGHP_00009 2e-30 WQ51_00220 K Helix-turn-helix domain
HGEILGHP_00010 1.3e-48
HGEILGHP_00011 6.7e-65 K Helix-turn-helix domain
HGEILGHP_00012 1.6e-272 S ABC transporter, ATP-binding protein
HGEILGHP_00013 5.4e-144 S Putative ABC-transporter type IV
HGEILGHP_00014 2e-106 NU mannosyl-glycoprotein
HGEILGHP_00015 2.2e-249 brnQ U Component of the transport system for branched-chain amino acids
HGEILGHP_00016 3.5e-230 S Uncharacterized protein conserved in bacteria (DUF2325)
HGEILGHP_00017 5.1e-201 nrnB S DHHA1 domain
HGEILGHP_00025 2.5e-200 xerS L Belongs to the 'phage' integrase family
HGEILGHP_00027 4.7e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HGEILGHP_00028 1.8e-75 marR K Transcriptional regulator, MarR family
HGEILGHP_00029 1.7e-100 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGEILGHP_00030 8.8e-51 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGEILGHP_00031 2.5e-31 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGEILGHP_00032 2e-148 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HGEILGHP_00033 9.6e-119 IQ reductase
HGEILGHP_00034 3e-58 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HGEILGHP_00035 4e-107 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HGEILGHP_00036 1.5e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGEILGHP_00037 4.8e-88 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HGEILGHP_00038 1.2e-127 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HGEILGHP_00045 4.9e-88
HGEILGHP_00046 1.1e-71 pnb C nitroreductase
HGEILGHP_00047 1.2e-29 XK27_00915 C Luciferase-like monooxygenase
HGEILGHP_00048 2e-137 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HGEILGHP_00049 1e-67 S Protein of unknown function (DUF3021)
HGEILGHP_00050 4.7e-73 K LytTr DNA-binding domain
HGEILGHP_00051 5.5e-21
HGEILGHP_00052 8.4e-120 ybhL S Belongs to the BI1 family
HGEILGHP_00053 1.6e-76 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HGEILGHP_00054 1.3e-190 S Protein of unknown function (DUF3114)
HGEILGHP_00055 4.2e-294 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGEILGHP_00056 2.6e-65 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGEILGHP_00057 4.6e-61 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGEILGHP_00058 8.9e-104 yvdD 3.2.2.10 S Belongs to the LOG family
HGEILGHP_00059 9.1e-62 S Domain of unknown function (DUF4828)
HGEILGHP_00060 1.3e-190 mocA S Oxidoreductase
HGEILGHP_00061 1.5e-231 yfmL L DEAD DEAH box helicase
HGEILGHP_00063 4.9e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGEILGHP_00064 2.1e-38
HGEILGHP_00065 2.3e-67 gtcA S Teichoic acid glycosylation protein
HGEILGHP_00066 3.9e-78 fld C Flavodoxin
HGEILGHP_00067 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HGEILGHP_00068 1.3e-220 arcT 2.6.1.1 E Aminotransferase
HGEILGHP_00069 5e-257 E Arginine ornithine antiporter
HGEILGHP_00070 1.5e-280 yjeM E Amino Acid
HGEILGHP_00071 1.5e-153 yihY S Belongs to the UPF0761 family
HGEILGHP_00072 1.9e-33 S Protein of unknown function (DUF2922)
HGEILGHP_00073 1.9e-30
HGEILGHP_00074 3.1e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
HGEILGHP_00075 4.5e-143 cps1D M Domain of unknown function (DUF4422)
HGEILGHP_00076 7e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HGEILGHP_00077 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
HGEILGHP_00078 0.0 2.7.7.6 M Peptidase family M23
HGEILGHP_00079 0.0 G Peptidase_C39 like family
HGEILGHP_00080 7.2e-24
HGEILGHP_00081 6.1e-101 L Transposase
HGEILGHP_00082 1.4e-71 natA S Domain of unknown function (DUF4162)
HGEILGHP_00083 5.4e-45 ysdA CP transmembrane transport
HGEILGHP_00085 2.4e-125 O Bacterial dnaA protein
HGEILGHP_00086 5.3e-113 L Integrase core domain
HGEILGHP_00088 8.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HGEILGHP_00089 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HGEILGHP_00090 8.8e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HGEILGHP_00091 1e-203 coiA 3.6.4.12 S Competence protein
HGEILGHP_00092 9.2e-264 pipD E Dipeptidase
HGEILGHP_00093 1.2e-114 yjbH Q Thioredoxin
HGEILGHP_00094 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
HGEILGHP_00095 3.9e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGEILGHP_00096 7.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HGEILGHP_00097 5e-53 EGP Major facilitator Superfamily
HGEILGHP_00098 1.6e-86 yaaU EGP Major facilitator Superfamily
HGEILGHP_00099 5.6e-24 yaaU EGP Major facilitator Superfamily
HGEILGHP_00100 2.6e-65 rmaI K Transcriptional regulator
HGEILGHP_00101 3e-38
HGEILGHP_00102 0.0 ydaO E amino acid
HGEILGHP_00103 3.4e-302 ybeC E amino acid
HGEILGHP_00104 8e-42 S Aminoacyl-tRNA editing domain
HGEILGHP_00105 6.5e-31 S YbaK proline--tRNA ligase associated domain protein
HGEILGHP_00106 9.4e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HGEILGHP_00107 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGEILGHP_00108 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HGEILGHP_00109 0.0 uup S ABC transporter, ATP-binding protein
HGEILGHP_00110 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
HGEILGHP_00111 1.1e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGEILGHP_00112 7.7e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
HGEILGHP_00113 1.8e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HGEILGHP_00114 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGEILGHP_00115 2.7e-39 ptsH G phosphocarrier protein HPR
HGEILGHP_00116 6.4e-27
HGEILGHP_00117 0.0 clpE O Belongs to the ClpA ClpB family
HGEILGHP_00118 1.7e-100 S Pfam:DUF3816
HGEILGHP_00119 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HGEILGHP_00120 4.8e-112
HGEILGHP_00121 1.3e-154 V ABC transporter, ATP-binding protein
HGEILGHP_00122 2.7e-64 gntR1 K Transcriptional regulator, GntR family
HGEILGHP_00124 0.0 M NlpC/P60 family
HGEILGHP_00125 9.6e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HGEILGHP_00126 4.7e-226 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGEILGHP_00127 3.3e-163 yueF S AI-2E family transporter
HGEILGHP_00128 2.2e-262 G Peptidase_C39 like family
HGEILGHP_00129 7.5e-152 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGEILGHP_00130 9e-103 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGEILGHP_00135 1.7e-14 arpU S Phage transcriptional regulator, ArpU family
HGEILGHP_00136 4.7e-107 S D5 N terminal like
HGEILGHP_00137 1.1e-46
HGEILGHP_00139 3.3e-12
HGEILGHP_00141 8.2e-14
HGEILGHP_00142 7.2e-19 K sequence-specific DNA binding
HGEILGHP_00143 3.9e-132 L Belongs to the 'phage' integrase family
HGEILGHP_00148 1.7e-14 arpU S Phage transcriptional regulator, ArpU family
HGEILGHP_00149 4.7e-107 S D5 N terminal like
HGEILGHP_00150 6.5e-69
HGEILGHP_00152 3.2e-13 L DnaD domain protein
HGEILGHP_00155 1.1e-07
HGEILGHP_00158 6.9e-46 S Phage regulatory protein Rha (Phage_pRha)
HGEILGHP_00159 3.1e-13 S Helix-turn-helix domain
HGEILGHP_00160 8.2e-10 K Helix-turn-helix XRE-family like proteins
HGEILGHP_00161 3.9e-132 L Belongs to the 'phage' integrase family
HGEILGHP_00164 3.5e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGEILGHP_00165 1.8e-65 K HxlR-like helix-turn-helix
HGEILGHP_00166 4.1e-62 S macrophage migration inhibitory factor
HGEILGHP_00167 2.7e-166 yqiG C Oxidoreductase
HGEILGHP_00169 2.4e-18
HGEILGHP_00170 1.3e-263 dtpT U amino acid peptide transporter
HGEILGHP_00171 1.9e-150 yjjH S Calcineurin-like phosphoesterase
HGEILGHP_00174 2.9e-111
HGEILGHP_00175 2.2e-249 EGP Major facilitator Superfamily
HGEILGHP_00176 4.6e-302 aspT P Predicted Permease Membrane Region
HGEILGHP_00177 1.5e-132 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HGEILGHP_00178 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HGEILGHP_00179 1e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGEILGHP_00180 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HGEILGHP_00181 0.0 yhgF K Tex-like protein N-terminal domain protein
HGEILGHP_00182 3.3e-85 ydcK S Belongs to the SprT family
HGEILGHP_00184 5.4e-77
HGEILGHP_00185 2.8e-179
HGEILGHP_00186 3.2e-181 fecB P Periplasmic binding protein
HGEILGHP_00187 6.8e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HGEILGHP_00188 6.8e-131 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGEILGHP_00189 2e-79 S Flavodoxin
HGEILGHP_00190 2.2e-64 moaE 2.8.1.12 H MoaE protein
HGEILGHP_00191 1.7e-35 moaD 2.8.1.12 H ThiS family
HGEILGHP_00192 7.8e-219 narK P Transporter, major facilitator family protein
HGEILGHP_00193 7.8e-163 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HGEILGHP_00194 1.2e-180
HGEILGHP_00195 6.1e-18
HGEILGHP_00196 4e-116 nreC K PFAM regulatory protein LuxR
HGEILGHP_00197 4.1e-187 comP 2.7.13.3 F Sensor histidine kinase
HGEILGHP_00198 8.8e-44
HGEILGHP_00199 1.5e-103 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HGEILGHP_00200 9.7e-83 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HGEILGHP_00201 6.1e-227 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HGEILGHP_00202 1.3e-79 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HGEILGHP_00203 7.2e-189 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HGEILGHP_00204 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HGEILGHP_00205 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HGEILGHP_00206 1.9e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HGEILGHP_00207 1.5e-129 narI 1.7.5.1 C Nitrate reductase
HGEILGHP_00208 8.5e-154 EG EamA-like transporter family
HGEILGHP_00209 1.2e-117 L Integrase
HGEILGHP_00210 1.9e-158 rssA S Phospholipase, patatin family
HGEILGHP_00211 2.9e-21 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HGEILGHP_00212 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HGEILGHP_00213 6.8e-33 L PFAM Integrase catalytic region
HGEILGHP_00214 9.8e-112 yvyE 3.4.13.9 S YigZ family
HGEILGHP_00215 6.6e-259 comFA L Helicase C-terminal domain protein
HGEILGHP_00216 1.2e-126 comFC S Competence protein
HGEILGHP_00217 3.8e-96 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGEILGHP_00218 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGEILGHP_00219 3.9e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HGEILGHP_00220 5.3e-32 KT PspC domain protein
HGEILGHP_00221 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HGEILGHP_00222 6.6e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HGEILGHP_00223 1.2e-154 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGEILGHP_00224 2.2e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HGEILGHP_00225 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HGEILGHP_00226 6.6e-136 yrjD S LUD domain
HGEILGHP_00227 1.6e-285 lutB C 4Fe-4S dicluster domain
HGEILGHP_00228 5.8e-157 lutA C Cysteine-rich domain
HGEILGHP_00229 1.1e-172 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HGEILGHP_00230 1.2e-211 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HGEILGHP_00231 1.2e-163 aatB ET PFAM extracellular solute-binding protein, family 3
HGEILGHP_00232 3.9e-87 ykhA 3.1.2.20 I Thioesterase superfamily
HGEILGHP_00233 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HGEILGHP_00234 5.1e-116 yfbR S HD containing hydrolase-like enzyme
HGEILGHP_00235 6.9e-14
HGEILGHP_00236 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HGEILGHP_00237 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HGEILGHP_00238 1.1e-245 steT E amino acid
HGEILGHP_00239 2.7e-160 rapZ S Displays ATPase and GTPase activities
HGEILGHP_00240 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HGEILGHP_00241 3.4e-169 whiA K May be required for sporulation
HGEILGHP_00243 8.8e-15
HGEILGHP_00244 1.7e-241 glpT G Major Facilitator Superfamily
HGEILGHP_00245 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HGEILGHP_00247 9.3e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HGEILGHP_00248 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HGEILGHP_00249 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGEILGHP_00250 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HGEILGHP_00251 7.1e-248 yifK E Amino acid permease
HGEILGHP_00252 2.4e-292 clcA P chloride
HGEILGHP_00253 1.8e-34 secG U Preprotein translocase
HGEILGHP_00254 1.7e-145 est 3.1.1.1 S Serine aminopeptidase, S33
HGEILGHP_00255 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HGEILGHP_00256 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HGEILGHP_00257 6.3e-105 yxjI
HGEILGHP_00258 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGEILGHP_00259 4.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HGEILGHP_00260 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HGEILGHP_00261 6.1e-88 K Acetyltransferase (GNAT) domain
HGEILGHP_00262 1.3e-75 S PAS domain
HGEILGHP_00263 3e-101 dnaQ 2.7.7.7 L DNA polymerase III
HGEILGHP_00264 1e-167 murB 1.3.1.98 M Cell wall formation
HGEILGHP_00265 5.9e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGEILGHP_00266 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HGEILGHP_00267 3.7e-249 fucP G Major Facilitator Superfamily
HGEILGHP_00268 2.5e-150 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGEILGHP_00269 1.1e-124 ybbR S YbbR-like protein
HGEILGHP_00270 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGEILGHP_00271 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HGEILGHP_00272 8.7e-53
HGEILGHP_00273 0.0 oatA I Acyltransferase
HGEILGHP_00274 3.5e-79 K Transcriptional regulator
HGEILGHP_00275 1e-145 XK27_02985 S Cof-like hydrolase
HGEILGHP_00276 1.9e-75 lytE M Lysin motif
HGEILGHP_00278 4.4e-132 K response regulator
HGEILGHP_00279 3e-268 yclK 2.7.13.3 T Histidine kinase
HGEILGHP_00280 2e-155 glcU U sugar transport
HGEILGHP_00281 1.5e-101 lacA 2.3.1.79 S Transferase hexapeptide repeat
HGEILGHP_00282 9e-264 pgi 5.3.1.9 G Belongs to the GPI family
HGEILGHP_00283 1.3e-28
HGEILGHP_00284 2.5e-217 xylR GK ROK family
HGEILGHP_00286 2.8e-260 xylT EGP Major facilitator Superfamily
HGEILGHP_00287 8.6e-173 rhaS2 K Transcriptional regulator, AraC family
HGEILGHP_00288 1.6e-290 xynT G MFS/sugar transport protein
HGEILGHP_00289 0.0 3.2.1.55 GH51 G Right handed beta helix region
HGEILGHP_00290 6e-20 pgdA 3.5.1.104 G polysaccharide deacetylase
HGEILGHP_00291 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
HGEILGHP_00292 2e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HGEILGHP_00293 1.9e-302 xylB 2.7.1.17 G Belongs to the FGGY kinase family
HGEILGHP_00294 1.2e-154 KT YcbB domain
HGEILGHP_00295 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGEILGHP_00296 7.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HGEILGHP_00297 3.9e-162 EG EamA-like transporter family
HGEILGHP_00298 1.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HGEILGHP_00299 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HGEILGHP_00300 8.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HGEILGHP_00301 0.0 copA 3.6.3.54 P P-type ATPase
HGEILGHP_00302 1.3e-87
HGEILGHP_00304 3.6e-57
HGEILGHP_00305 2.5e-249 yjcE P Sodium proton antiporter
HGEILGHP_00311 1.7e-14 arpU S Phage transcriptional regulator, ArpU family
HGEILGHP_00312 4.7e-107 S D5 N terminal like
HGEILGHP_00313 7.6e-31 L PFAM transposase IS200-family protein
HGEILGHP_00314 4.9e-65 XK27_06920 S Protein of unknown function (DUF1700)
HGEILGHP_00315 1.7e-55 znuA P Belongs to the bacterial solute-binding protein 9 family
HGEILGHP_00316 4.5e-152 K Transcriptional regulator, LysR family
HGEILGHP_00317 3.8e-246 E Peptidase family M20/M25/M40
HGEILGHP_00318 2.3e-218 G Transporter, major facilitator family protein
HGEILGHP_00319 3.1e-206 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGEILGHP_00320 3.8e-207 L Transposase
HGEILGHP_00321 7.6e-11 M Glycosyl transferase family 8
HGEILGHP_00322 3.9e-47 M family 8
HGEILGHP_00323 2.3e-110 nss M transferase activity, transferring glycosyl groups
HGEILGHP_00324 3e-162 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HGEILGHP_00325 1.6e-197 M transferase activity, transferring glycosyl groups
HGEILGHP_00326 5e-215 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HGEILGHP_00327 3.5e-155 asp3 S Accessory Sec secretory system ASP3
HGEILGHP_00328 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HGEILGHP_00329 1.5e-227 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HGEILGHP_00330 8.2e-193 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HGEILGHP_00333 3.3e-302 M family 8
HGEILGHP_00334 2e-102 cpsJ S glycosyl transferase family 2
HGEILGHP_00335 0.0 M LPXTG-motif cell wall anchor domain protein
HGEILGHP_00336 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HGEILGHP_00337 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
HGEILGHP_00338 2.6e-139 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HGEILGHP_00339 2.5e-118 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HGEILGHP_00341 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGEILGHP_00342 7.1e-166 T Calcineurin-like phosphoesterase superfamily domain
HGEILGHP_00343 3.1e-223 mdtG EGP Major facilitator Superfamily
HGEILGHP_00344 5.7e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HGEILGHP_00345 3e-220 yxjG_1 E methionine synthase, vitamin-B12 independent
HGEILGHP_00346 1.1e-143 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
HGEILGHP_00347 2.6e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HGEILGHP_00348 5.7e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGEILGHP_00349 7.3e-172 lacZ 3.2.1.23 G -beta-galactosidase
HGEILGHP_00350 1e-121 lacZ 3.2.1.23 G -beta-galactosidase
HGEILGHP_00351 0.0 lacS G Transporter
HGEILGHP_00352 2.4e-184 lacR K Transcriptional regulator
HGEILGHP_00353 6.6e-84
HGEILGHP_00354 9.7e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HGEILGHP_00355 1.2e-52 S Mazg nucleotide pyrophosphohydrolase
HGEILGHP_00356 3.8e-34
HGEILGHP_00357 1.4e-264 L Transposase
HGEILGHP_00358 2.8e-224 aadAT EK Aminotransferase, class I
HGEILGHP_00360 1.3e-235 M Glycosyl transferase family group 2
HGEILGHP_00361 8.8e-78 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGEILGHP_00362 6.2e-111 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HGEILGHP_00363 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGEILGHP_00364 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HGEILGHP_00365 1e-47
HGEILGHP_00367 2e-31 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HGEILGHP_00368 2.2e-229 L Integrase core domain
HGEILGHP_00369 1.4e-54
HGEILGHP_00370 4.8e-114 frnE Q DSBA-like thioredoxin domain
HGEILGHP_00371 6.3e-162 I alpha/beta hydrolase fold
HGEILGHP_00372 8.9e-16 XK27_13030
HGEILGHP_00373 3.8e-159 L hmm pf00665
HGEILGHP_00374 5.4e-113 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HGEILGHP_00376 1.9e-115 S GyrI-like small molecule binding domain
HGEILGHP_00377 8e-120 yhiD S MgtC family
HGEILGHP_00378 6.2e-91 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGEILGHP_00379 1.6e-191 V Beta-lactamase
HGEILGHP_00380 5.3e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGEILGHP_00381 1.6e-88 XK27_08850 J Aminoacyl-tRNA editing domain
HGEILGHP_00382 7.6e-20 relB L Addiction module antitoxin, RelB DinJ family
HGEILGHP_00383 8.9e-24
HGEILGHP_00384 3.5e-286 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HGEILGHP_00385 3.3e-117 K LytTr DNA-binding domain
HGEILGHP_00386 1.5e-212 2.7.13.3 T GHKL domain
HGEILGHP_00389 2.8e-07
HGEILGHP_00392 4.4e-161 mleP3 S Membrane transport protein
HGEILGHP_00393 1e-122 T Transcriptional regulatory protein, C terminal
HGEILGHP_00394 1.5e-239 T GHKL domain
HGEILGHP_00395 1.8e-108 S Peptidase propeptide and YPEB domain
HGEILGHP_00396 1.8e-115 P nitric oxide dioxygenase activity
HGEILGHP_00397 2.4e-10 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HGEILGHP_00398 4.2e-53 yphJ 4.1.1.44 S decarboxylase
HGEILGHP_00399 5.6e-115 S Oxidoreductase, aldo keto reductase family protein
HGEILGHP_00400 2.2e-38 C Flavodoxin
HGEILGHP_00401 1.5e-92 padC Q Phenolic acid decarboxylase
HGEILGHP_00402 1.1e-87 padR K Virulence activator alpha C-term
HGEILGHP_00403 1.4e-165 ypuA S Protein of unknown function (DUF1002)
HGEILGHP_00404 6.7e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HGEILGHP_00405 1.3e-151 K Transcriptional regulator
HGEILGHP_00406 5.6e-158 akr5f 1.1.1.346 S reductase
HGEILGHP_00407 4.1e-62 yneR
HGEILGHP_00408 8.5e-130 yfeJ 6.3.5.2 F glutamine amidotransferase
HGEILGHP_00409 1.4e-17
HGEILGHP_00410 5.1e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HGEILGHP_00411 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
HGEILGHP_00412 1.3e-29 yjaB_1 K Acetyltransferase (GNAT) domain
HGEILGHP_00413 2.9e-88 folT S ECF transporter, substrate-specific component
HGEILGHP_00414 0.0 pepN 3.4.11.2 E aminopeptidase
HGEILGHP_00415 1.6e-109 ylbE GM NAD dependent epimerase dehydratase family protein
HGEILGHP_00416 5.4e-253 pepC 3.4.22.40 E aminopeptidase
HGEILGHP_00417 2.5e-209 EGP Major facilitator Superfamily
HGEILGHP_00418 1.3e-227
HGEILGHP_00419 7.3e-77 K Transcriptional regulator, HxlR family
HGEILGHP_00420 4.8e-108 XK27_02070 S Nitroreductase family
HGEILGHP_00421 2.8e-51 hxlR K Transcriptional regulator, HxlR family
HGEILGHP_00422 3e-10 GM NmrA-like family
HGEILGHP_00423 1.5e-71 elaA S Gnat family
HGEILGHP_00424 1.8e-39 S Cytochrome B5
HGEILGHP_00425 5.4e-09 S Cytochrome B5
HGEILGHP_00426 3e-40 S Cytochrome B5
HGEILGHP_00427 8.8e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
HGEILGHP_00429 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGEILGHP_00430 4.1e-240 E amino acid
HGEILGHP_00431 4e-253 npp S type I phosphodiesterase nucleotide pyrophosphatase
HGEILGHP_00432 8.1e-20 yxiO S Vacuole effluxer Atg22 like
HGEILGHP_00433 1.1e-116 yxiO S Vacuole effluxer Atg22 like
HGEILGHP_00434 2.3e-32 yxiO S Vacuole effluxer Atg22 like
HGEILGHP_00436 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGEILGHP_00437 7.8e-22
HGEILGHP_00438 3e-290 mntH P H( )-stimulated, divalent metal cation uptake system
HGEILGHP_00439 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HGEILGHP_00440 7.5e-86 ygfC K transcriptional regulator (TetR family)
HGEILGHP_00441 5.4e-171 hrtB V ABC transporter permease
HGEILGHP_00442 3.9e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HGEILGHP_00443 0.0 yhcA V ABC transporter, ATP-binding protein
HGEILGHP_00444 5.1e-37
HGEILGHP_00445 4.1e-50 czrA K Transcriptional regulator, ArsR family
HGEILGHP_00446 2.7e-241 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGEILGHP_00447 8.7e-173 scrR K Transcriptional regulator, LacI family
HGEILGHP_00448 1e-24
HGEILGHP_00449 1.6e-106
HGEILGHP_00450 2.1e-208 yttB EGP Major facilitator Superfamily
HGEILGHP_00451 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HGEILGHP_00452 8.5e-87
HGEILGHP_00453 9.6e-107 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HGEILGHP_00454 1.5e-258 S Putative peptidoglycan binding domain
HGEILGHP_00455 1.2e-14
HGEILGHP_00456 6.4e-122 yciB M ErfK YbiS YcfS YnhG
HGEILGHP_00458 6.3e-97
HGEILGHP_00459 1.1e-217 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGEILGHP_00460 4.5e-125 S Alpha beta hydrolase
HGEILGHP_00461 2.1e-210 gldA 1.1.1.6 C dehydrogenase
HGEILGHP_00462 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGEILGHP_00463 8.4e-41
HGEILGHP_00464 2.1e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
HGEILGHP_00465 1.1e-281 S C4-dicarboxylate anaerobic carrier
HGEILGHP_00466 1.3e-249 nhaC C Na H antiporter NhaC
HGEILGHP_00467 9.5e-242 pbuX F xanthine permease
HGEILGHP_00468 7.3e-280 pipD E Dipeptidase
HGEILGHP_00469 9.7e-169 corA P CorA-like Mg2+ transporter protein
HGEILGHP_00470 3.6e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGEILGHP_00471 2.3e-131 terC P membrane
HGEILGHP_00472 1.1e-55 trxA O Belongs to the thioredoxin family
HGEILGHP_00473 1.1e-95 L nuclease
HGEILGHP_00474 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HGEILGHP_00475 3.6e-70
HGEILGHP_00476 8.3e-102 fic D Fic/DOC family
HGEILGHP_00477 1.1e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HGEILGHP_00478 1.9e-150 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HGEILGHP_00479 3.8e-227
HGEILGHP_00480 0.0
HGEILGHP_00481 0.0
HGEILGHP_00482 3.5e-24
HGEILGHP_00483 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HGEILGHP_00484 1.8e-47 gcvH E glycine cleavage
HGEILGHP_00485 1.1e-220 rodA D Belongs to the SEDS family
HGEILGHP_00486 2.3e-31 S Protein of unknown function (DUF2969)
HGEILGHP_00487 7.2e-178 mbl D Cell shape determining protein MreB Mrl
HGEILGHP_00488 3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGEILGHP_00489 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HGEILGHP_00490 1.3e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HGEILGHP_00491 2.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGEILGHP_00492 7.4e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGEILGHP_00493 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGEILGHP_00494 1.5e-92 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGEILGHP_00495 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGEILGHP_00496 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGEILGHP_00497 4.7e-123 atpB C it plays a direct role in the translocation of protons across the membrane
HGEILGHP_00498 5.9e-233 pyrP F Permease
HGEILGHP_00499 9.1e-128 yibF S overlaps another CDS with the same product name
HGEILGHP_00500 9.9e-192 yibE S overlaps another CDS with the same product name
HGEILGHP_00501 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGEILGHP_00502 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGEILGHP_00503 6e-230 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGEILGHP_00504 2.7e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HGEILGHP_00505 2.3e-164 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HGEILGHP_00506 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGEILGHP_00507 6e-108 tdk 2.7.1.21 F thymidine kinase
HGEILGHP_00508 5.8e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HGEILGHP_00509 9.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HGEILGHP_00510 5.2e-222 arcD U Amino acid permease
HGEILGHP_00511 2.8e-260 E Arginine ornithine antiporter
HGEILGHP_00512 1e-78 argR K Regulates arginine biosynthesis genes
HGEILGHP_00513 4.1e-239 arcA 3.5.3.6 E Arginine
HGEILGHP_00514 1.6e-17 ampC V Beta-lactamase
HGEILGHP_00515 3.7e-138 ampC V Beta-lactamase
HGEILGHP_00516 2.9e-33
HGEILGHP_00517 0.0 M domain protein
HGEILGHP_00518 2e-91
HGEILGHP_00520 3.9e-132 L Belongs to the 'phage' integrase family
HGEILGHP_00521 3.9e-50 L Bacterial dnaA protein
HGEILGHP_00522 3.5e-87 L Transposase
HGEILGHP_00523 5.9e-238 L Integrase core domain
HGEILGHP_00524 4.5e-132 O Bacterial dnaA protein
HGEILGHP_00525 6.1e-82 L Transposase
HGEILGHP_00526 9e-283 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HGEILGHP_00527 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HGEILGHP_00528 1.7e-149 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGEILGHP_00529 3.8e-159 L hmm pf00665
HGEILGHP_00530 4.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGEILGHP_00531 9.4e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGEILGHP_00532 2.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGEILGHP_00533 7.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGEILGHP_00534 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HGEILGHP_00535 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HGEILGHP_00536 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGEILGHP_00537 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HGEILGHP_00538 9e-103 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGEILGHP_00539 2.1e-76 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGEILGHP_00540 1.8e-59 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HGEILGHP_00541 8.1e-145 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGEILGHP_00542 1.7e-67 L Helix-turn-helix domain
HGEILGHP_00543 9.6e-75 S polysaccharide biosynthetic process
HGEILGHP_00544 6.3e-43 MA20_43635 M Capsular polysaccharide synthesis protein
HGEILGHP_00545 2.6e-41 pglI 2.4.1.293 GT2 M Glycosyltransferase like family 2
HGEILGHP_00547 1.6e-88 lsgF M Glycosyl transferase family 2
HGEILGHP_00548 8.1e-53 pglC M Bacterial sugar transferase
HGEILGHP_00549 7e-117 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HGEILGHP_00550 3.5e-136 epsB M biosynthesis protein
HGEILGHP_00551 1.2e-161 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HGEILGHP_00552 6.5e-69 K Transcriptional regulator, HxlR family
HGEILGHP_00553 2.2e-128
HGEILGHP_00554 5.8e-103 K DNA-templated transcription, initiation
HGEILGHP_00555 2.8e-35
HGEILGHP_00556 2.2e-82
HGEILGHP_00557 4.3e-291 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGEILGHP_00558 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HGEILGHP_00559 0.0 yjbQ P TrkA C-terminal domain protein
HGEILGHP_00560 2.9e-273 pipD E Dipeptidase
HGEILGHP_00563 7.1e-200 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HGEILGHP_00564 2.3e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HGEILGHP_00565 3e-159 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HGEILGHP_00566 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGEILGHP_00567 2.9e-144 rfbJ M Glycosyl transferase family 2
HGEILGHP_00568 1.1e-81
HGEILGHP_00569 2.4e-73 S Acyltransferase family
HGEILGHP_00570 1.1e-79 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HGEILGHP_00571 4.4e-66 S Glycosyltransferase like family
HGEILGHP_00572 6.9e-77 rgpB GT2 M Glycosyl transferase family 2
HGEILGHP_00573 8.7e-28 M biosynthesis protein
HGEILGHP_00574 4.5e-89 cps3F
HGEILGHP_00575 2.3e-75 M transferase activity, transferring glycosyl groups
HGEILGHP_00576 3.9e-209 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HGEILGHP_00577 3.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
HGEILGHP_00578 7.2e-89 L Transposase
HGEILGHP_00579 3.9e-117 5.1.1.13 M Asp/Glu/Hydantoin racemase
HGEILGHP_00580 1.1e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
HGEILGHP_00581 9.9e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HGEILGHP_00582 4.2e-95 dps P Belongs to the Dps family
HGEILGHP_00583 1.1e-33 copZ C Heavy-metal-associated domain
HGEILGHP_00584 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HGEILGHP_00585 1.3e-102
HGEILGHP_00586 6.8e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGEILGHP_00587 2.5e-186 yegS 2.7.1.107 G Lipid kinase
HGEILGHP_00588 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGEILGHP_00589 4.7e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HGEILGHP_00590 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGEILGHP_00591 1.2e-202 camS S sex pheromone
HGEILGHP_00592 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGEILGHP_00593 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HGEILGHP_00594 1.8e-212 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGEILGHP_00595 3.5e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HGEILGHP_00596 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
HGEILGHP_00597 2.7e-140 IQ reductase
HGEILGHP_00598 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HGEILGHP_00599 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HGEILGHP_00600 1.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HGEILGHP_00601 2.8e-140 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGEILGHP_00602 7.8e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGEILGHP_00603 6.3e-143 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGEILGHP_00604 1.1e-62 rplQ J Ribosomal protein L17
HGEILGHP_00605 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGEILGHP_00606 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGEILGHP_00607 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGEILGHP_00608 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HGEILGHP_00609 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGEILGHP_00610 1.5e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HGEILGHP_00611 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HGEILGHP_00612 8.9e-64 rplO J Binds to the 23S rRNA
HGEILGHP_00613 2.9e-24 rpmD J Ribosomal protein L30
HGEILGHP_00614 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGEILGHP_00615 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGEILGHP_00616 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGEILGHP_00617 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGEILGHP_00618 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGEILGHP_00619 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGEILGHP_00620 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGEILGHP_00621 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGEILGHP_00622 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGEILGHP_00623 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HGEILGHP_00624 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HGEILGHP_00625 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGEILGHP_00626 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGEILGHP_00627 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGEILGHP_00628 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGEILGHP_00629 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HGEILGHP_00630 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HGEILGHP_00631 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGEILGHP_00632 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
HGEILGHP_00636 2.2e-141 D CobQ CobB MinD ParA nucleotide binding domain protein
HGEILGHP_00637 2.6e-38
HGEILGHP_00638 3.6e-33 S Flavodoxin-like fold
HGEILGHP_00641 2.3e-120 lanM V Domain of unknown function (DUF4135)
HGEILGHP_00642 2.8e-174 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HGEILGHP_00644 9.3e-17 2.7.13.3 T GHKL domain
HGEILGHP_00645 2.2e-36 K LytTr DNA-binding domain
HGEILGHP_00646 1.6e-42
HGEILGHP_00647 3.3e-93 L Integrase
HGEILGHP_00648 1.7e-29 relB L RelB antitoxin
HGEILGHP_00649 1.8e-42 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HGEILGHP_00656 4.3e-83 usp6 T universal stress protein
HGEILGHP_00657 4.4e-46
HGEILGHP_00658 5e-235 rarA L recombination factor protein RarA
HGEILGHP_00659 6e-85 yueI S Protein of unknown function (DUF1694)
HGEILGHP_00660 2e-21
HGEILGHP_00661 3.1e-74 4.4.1.5 E Glyoxalase
HGEILGHP_00662 1.2e-137 S Membrane
HGEILGHP_00663 3.4e-135 S Belongs to the UPF0246 family
HGEILGHP_00664 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HGEILGHP_00665 4.9e-262 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HGEILGHP_00666 1.3e-235 pbuG S permease
HGEILGHP_00667 3.8e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HGEILGHP_00668 4.3e-286 gadC E amino acid
HGEILGHP_00669 1.1e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
HGEILGHP_00670 6.9e-292 gadC E amino acid
HGEILGHP_00671 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGEILGHP_00672 1.1e-250 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HGEILGHP_00673 1.5e-214 iscS2 2.8.1.7 E Aminotransferase class V
HGEILGHP_00674 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGEILGHP_00675 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HGEILGHP_00676 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
HGEILGHP_00677 1.4e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HGEILGHP_00678 1.7e-307 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HGEILGHP_00679 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HGEILGHP_00680 4.5e-230 ndh 1.6.99.3 C NADH dehydrogenase
HGEILGHP_00681 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGEILGHP_00682 2.1e-122 radC L DNA repair protein
HGEILGHP_00683 1.7e-179 mreB D cell shape determining protein MreB
HGEILGHP_00684 7.7e-152 mreC M Involved in formation and maintenance of cell shape
HGEILGHP_00685 7.3e-92 mreD M rod shape-determining protein MreD
HGEILGHP_00686 3.2e-102 glnP P ABC transporter permease
HGEILGHP_00687 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGEILGHP_00688 1.3e-159 aatB ET ABC transporter substrate-binding protein
HGEILGHP_00689 6.6e-229 ymfF S Peptidase M16 inactive domain protein
HGEILGHP_00690 1.8e-248 ymfH S Peptidase M16
HGEILGHP_00691 2.4e-136 ymfM S Helix-turn-helix domain
HGEILGHP_00692 3.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGEILGHP_00693 3.9e-229 cinA 3.5.1.42 S Belongs to the CinA family
HGEILGHP_00694 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGEILGHP_00695 2.8e-208 rny S Endoribonuclease that initiates mRNA decay
HGEILGHP_00696 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGEILGHP_00697 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGEILGHP_00698 2.5e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HGEILGHP_00699 4.5e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HGEILGHP_00700 1.3e-196 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HGEILGHP_00701 2.8e-31 yajC U Preprotein translocase
HGEILGHP_00702 3.6e-182 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HGEILGHP_00703 1.1e-232 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HGEILGHP_00704 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGEILGHP_00705 4.1e-43 yrzL S Belongs to the UPF0297 family
HGEILGHP_00706 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGEILGHP_00707 6.1e-48 yrzB S Belongs to the UPF0473 family
HGEILGHP_00708 1e-85 cvpA S Colicin V production protein
HGEILGHP_00709 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HGEILGHP_00710 6.1e-54 trxA O Belongs to the thioredoxin family
HGEILGHP_00711 1.3e-96 yslB S Protein of unknown function (DUF2507)
HGEILGHP_00712 5e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HGEILGHP_00713 7e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGEILGHP_00714 6.9e-95 S Phosphoesterase
HGEILGHP_00715 3.6e-76 ykuL S (CBS) domain
HGEILGHP_00716 1e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HGEILGHP_00717 3.1e-148 ykuT M mechanosensitive ion channel
HGEILGHP_00718 1.2e-36 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HGEILGHP_00719 8.3e-28
HGEILGHP_00720 1.2e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HGEILGHP_00721 1.1e-181 ccpA K catabolite control protein A
HGEILGHP_00722 1.9e-134
HGEILGHP_00723 1.6e-132 yebC K Transcriptional regulatory protein
HGEILGHP_00724 3.3e-183 comGA NU Type II IV secretion system protein
HGEILGHP_00725 2.5e-181 comGB NU type II secretion system
HGEILGHP_00726 1.2e-46 comGC U competence protein ComGC
HGEILGHP_00727 1.4e-77 NU general secretion pathway protein
HGEILGHP_00728 1.6e-40
HGEILGHP_00729 3.1e-69
HGEILGHP_00730 1.3e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
HGEILGHP_00731 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGEILGHP_00732 9.7e-117 S Calcineurin-like phosphoesterase
HGEILGHP_00733 4.4e-100 yutD S Protein of unknown function (DUF1027)
HGEILGHP_00734 4.7e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HGEILGHP_00735 1.2e-112 S Protein of unknown function (DUF1461)
HGEILGHP_00736 1.6e-109 dedA S SNARE-like domain protein
HGEILGHP_00737 8.6e-207 yacL S domain protein
HGEILGHP_00738 3.9e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGEILGHP_00739 1.5e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HGEILGHP_00740 7.2e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HGEILGHP_00741 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HGEILGHP_00742 9.5e-266 pepC 3.4.22.40 E Peptidase C1-like family
HGEILGHP_00743 2.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HGEILGHP_00744 7.7e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGEILGHP_00745 3.2e-119 tcyB E ABC transporter
HGEILGHP_00746 5.9e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HGEILGHP_00747 5.4e-169 I alpha/beta hydrolase fold
HGEILGHP_00748 6e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGEILGHP_00749 0.0 S Bacterial membrane protein, YfhO
HGEILGHP_00750 5.9e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HGEILGHP_00751 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HGEILGHP_00752 8.7e-264 L Transposase
HGEILGHP_00753 1.2e-144 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HGEILGHP_00754 2.8e-76 tlpA2 L Transposase IS200 like
HGEILGHP_00755 8.7e-229 L transposase, IS605 OrfB family
HGEILGHP_00756 1.3e-38
HGEILGHP_00757 1.8e-209 L Belongs to the 'phage' integrase family
HGEILGHP_00758 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HGEILGHP_00759 6.8e-262 yfnA E amino acid
HGEILGHP_00760 1.3e-142 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HGEILGHP_00761 7.6e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGEILGHP_00762 2.7e-39 ylqC S Belongs to the UPF0109 family
HGEILGHP_00763 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HGEILGHP_00764 3.9e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGEILGHP_00765 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HGEILGHP_00766 4.8e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HGEILGHP_00767 0.0 smc D Required for chromosome condensation and partitioning
HGEILGHP_00768 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HGEILGHP_00769 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGEILGHP_00770 1.9e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HGEILGHP_00771 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGEILGHP_00772 0.0 yloV S DAK2 domain fusion protein YloV
HGEILGHP_00773 4.7e-58 asp S Asp23 family, cell envelope-related function
HGEILGHP_00774 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HGEILGHP_00775 1.4e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HGEILGHP_00776 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HGEILGHP_00777 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HGEILGHP_00778 0.0 KLT serine threonine protein kinase
HGEILGHP_00779 2.5e-130 stp 3.1.3.16 T phosphatase
HGEILGHP_00780 3.2e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGEILGHP_00781 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGEILGHP_00782 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGEILGHP_00783 3e-210 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGEILGHP_00784 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HGEILGHP_00785 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HGEILGHP_00786 1.7e-54
HGEILGHP_00787 6.1e-262 recN L May be involved in recombinational repair of damaged DNA
HGEILGHP_00788 4.8e-76 argR K Regulates arginine biosynthesis genes
HGEILGHP_00789 8.4e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HGEILGHP_00790 3.8e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HGEILGHP_00791 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGEILGHP_00792 6.7e-227 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HGEILGHP_00793 1.2e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGEILGHP_00794 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGEILGHP_00795 8.4e-70 yqhY S Asp23 family, cell envelope-related function
HGEILGHP_00796 2e-110 J 2'-5' RNA ligase superfamily
HGEILGHP_00797 2e-197 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HGEILGHP_00798 3.8e-128 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGEILGHP_00799 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HGEILGHP_00800 1.6e-54 ysxB J Cysteine protease Prp
HGEILGHP_00801 6.8e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HGEILGHP_00802 5.8e-112 K Transcriptional regulator
HGEILGHP_00805 7.4e-86 dut S Protein conserved in bacteria
HGEILGHP_00806 1e-182
HGEILGHP_00807 1e-151
HGEILGHP_00808 8.2e-51 S Iron-sulfur cluster assembly protein
HGEILGHP_00809 4.2e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGEILGHP_00810 9.7e-155 P Belongs to the nlpA lipoprotein family
HGEILGHP_00811 3.9e-12
HGEILGHP_00812 3.3e-222 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HGEILGHP_00813 1.5e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGEILGHP_00814 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
HGEILGHP_00815 9.1e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGEILGHP_00816 5.9e-22 S Protein of unknown function (DUF3042)
HGEILGHP_00817 5e-66 yqhL P Rhodanese-like protein
HGEILGHP_00818 7.3e-183 glk 2.7.1.2 G Glucokinase
HGEILGHP_00819 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HGEILGHP_00820 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
HGEILGHP_00821 1.4e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGEILGHP_00822 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HGEILGHP_00823 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HGEILGHP_00824 0.0 S membrane
HGEILGHP_00825 8.8e-71 yneR S Belongs to the HesB IscA family
HGEILGHP_00826 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGEILGHP_00827 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HGEILGHP_00828 2.1e-114 rlpA M PFAM NLP P60 protein
HGEILGHP_00829 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGEILGHP_00830 1.5e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGEILGHP_00831 1.5e-58 yodB K Transcriptional regulator, HxlR family
HGEILGHP_00832 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGEILGHP_00833 5.4e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGEILGHP_00834 5e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HGEILGHP_00835 9.1e-170 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGEILGHP_00836 3.5e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HGEILGHP_00837 1.7e-230 V MatE
HGEILGHP_00838 6.2e-266 yjeM E Amino Acid
HGEILGHP_00839 1.2e-277 arlS 2.7.13.3 T Histidine kinase
HGEILGHP_00840 1.5e-121 K response regulator
HGEILGHP_00841 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HGEILGHP_00842 2.4e-98 yceD S Uncharacterized ACR, COG1399
HGEILGHP_00843 3.6e-213 ylbM S Belongs to the UPF0348 family
HGEILGHP_00844 1.9e-138 yqeM Q Methyltransferase
HGEILGHP_00845 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HGEILGHP_00846 8.6e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HGEILGHP_00847 1.1e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGEILGHP_00848 1.9e-47 yhbY J RNA-binding protein
HGEILGHP_00849 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
HGEILGHP_00850 1.7e-96 yqeG S HAD phosphatase, family IIIA
HGEILGHP_00851 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGEILGHP_00852 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HGEILGHP_00853 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGEILGHP_00854 1.1e-172 dnaI L Primosomal protein DnaI
HGEILGHP_00855 4.4e-226 dnaB L replication initiation and membrane attachment
HGEILGHP_00856 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HGEILGHP_00857 2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGEILGHP_00858 8.5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HGEILGHP_00859 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGEILGHP_00860 1e-119 yoaK S Protein of unknown function (DUF1275)
HGEILGHP_00861 5.5e-119 ybhL S Belongs to the BI1 family
HGEILGHP_00862 5.8e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HGEILGHP_00863 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HGEILGHP_00864 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HGEILGHP_00865 7.5e-58 ytzB S Small secreted protein
HGEILGHP_00866 6.3e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
HGEILGHP_00867 2.8e-76 tlpA2 L Transposase IS200 like
HGEILGHP_00868 8.7e-229 L transposase, IS605 OrfB family
HGEILGHP_00872 3e-07
HGEILGHP_00874 1.4e-57 L HNH nucleases
HGEILGHP_00875 1.1e-64 L Phage terminase, small subunit
HGEILGHP_00876 6.6e-289 S overlaps another CDS with the same product name
HGEILGHP_00878 6.8e-199 S Phage portal protein
HGEILGHP_00879 1.2e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HGEILGHP_00880 1.9e-07 S Phage capsid family
HGEILGHP_00881 4.6e-50 S Phage gp6-like head-tail connector protein
HGEILGHP_00882 9.8e-11 S Phage head-tail joining protein
HGEILGHP_00883 9.8e-34 S exonuclease activity
HGEILGHP_00884 2.3e-20 S Protein of unknown function (DUF806)
HGEILGHP_00885 9.6e-80 S Phage tail tube protein
HGEILGHP_00886 5.3e-14 S Phage tail assembly chaperone proteins, TAC
HGEILGHP_00887 9e-231 M Phage tail tape measure protein TP901
HGEILGHP_00888 1.7e-85 S Phage tail protein
HGEILGHP_00889 4.4e-145 ydhO 3.4.14.13 M Prophage endopeptidase tail
HGEILGHP_00890 9.3e-82 GT2,GT4 LM gp58-like protein
HGEILGHP_00897 1e-33 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HGEILGHP_00898 8.4e-151 lysA2 M Glycosyl hydrolases family 25
HGEILGHP_00900 3e-30 S Protein of unknown function (DUF2929)
HGEILGHP_00901 0.0 dnaE 2.7.7.7 L DNA polymerase
HGEILGHP_00902 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HGEILGHP_00903 1.5e-166 cvfB S S1 domain
HGEILGHP_00904 9.1e-164 xerD D recombinase XerD
HGEILGHP_00905 1.6e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HGEILGHP_00906 2.5e-136 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HGEILGHP_00907 6.1e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HGEILGHP_00908 1.5e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HGEILGHP_00909 3.8e-102 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HGEILGHP_00910 4.7e-188 ypbB 5.1.3.1 S Helix-turn-helix domain
HGEILGHP_00911 2.9e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HGEILGHP_00912 8.5e-14 M Lysin motif
HGEILGHP_00913 9.9e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HGEILGHP_00914 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HGEILGHP_00915 1.2e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HGEILGHP_00916 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HGEILGHP_00917 1.5e-236 S Tetratricopeptide repeat protein
HGEILGHP_00918 3.9e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HGEILGHP_00919 0.0 yfmR S ABC transporter, ATP-binding protein
HGEILGHP_00920 2.2e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HGEILGHP_00921 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HGEILGHP_00922 5.3e-113 hlyIII S protein, hemolysin III
HGEILGHP_00923 4.4e-152 DegV S EDD domain protein, DegV family
HGEILGHP_00924 3.4e-169 ypmR E lipolytic protein G-D-S-L family
HGEILGHP_00925 6.9e-107 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HGEILGHP_00926 4.4e-35 yozE S Belongs to the UPF0346 family
HGEILGHP_00927 3.2e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGEILGHP_00928 2.7e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGEILGHP_00929 5.6e-158 dprA LU DNA protecting protein DprA
HGEILGHP_00930 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGEILGHP_00931 1.6e-168 lacX 5.1.3.3 G Aldose 1-epimerase
HGEILGHP_00932 7.9e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HGEILGHP_00933 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGEILGHP_00934 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HGEILGHP_00935 5.4e-83 F NUDIX domain
HGEILGHP_00936 3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HGEILGHP_00937 1.1e-68 yqkB S Belongs to the HesB IscA family
HGEILGHP_00938 4.2e-50
HGEILGHP_00940 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HGEILGHP_00941 2.4e-60 asp S Asp23 family, cell envelope-related function
HGEILGHP_00942 2.1e-25
HGEILGHP_00943 1.2e-94
HGEILGHP_00944 3.7e-290 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HGEILGHP_00945 5.2e-184 K Transcriptional regulator, LacI family
HGEILGHP_00946 1.3e-233 gntT EG Gluconate
HGEILGHP_00947 4.5e-296 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HGEILGHP_00948 3.2e-95 K Acetyltransferase (GNAT) domain
HGEILGHP_00949 5.4e-47
HGEILGHP_00950 2.2e-23
HGEILGHP_00951 2.2e-44
HGEILGHP_00952 8e-53 yhaI S Protein of unknown function (DUF805)
HGEILGHP_00953 1.5e-57 S Uncharacterised protein family (UPF0236)
HGEILGHP_00954 3.3e-250 menF 5.4.4.2 HQ chorismate binding enzyme
HGEILGHP_00955 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HGEILGHP_00956 1.2e-154 menH 2.2.1.9, 4.2.99.20, 6.2.1.26 I Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HGEILGHP_00957 1.1e-204 ydiN G Major Facilitator Superfamily
HGEILGHP_00958 2.3e-207 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGEILGHP_00959 1.2e-230 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HGEILGHP_00960 1.9e-79 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGEILGHP_00961 1.1e-74 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGEILGHP_00962 1.3e-105 yocS S SBF-like CPA transporter family (DUF4137)
HGEILGHP_00963 2.5e-131 L Transposase
HGEILGHP_00964 3.9e-50 L Bacterial dnaA protein
HGEILGHP_00965 8.7e-229 L transposase, IS605 OrfB family
HGEILGHP_00966 2.8e-76 tlpA2 L Transposase IS200 like
HGEILGHP_00967 1.9e-30 S Membrane
HGEILGHP_00969 6.9e-43
HGEILGHP_00970 2.8e-19
HGEILGHP_00971 5.9e-70 S Pfam:DUF955
HGEILGHP_00972 4.4e-26 3.4.21.88 K Helix-turn-helix domain
HGEILGHP_00975 9.5e-66 S DNA binding
HGEILGHP_00982 1.6e-18
HGEILGHP_00986 4.2e-63 S Bacteriophage Mu Gam like protein
HGEILGHP_00987 6.6e-28 S Protein of unknown function (DUF1071)
HGEILGHP_00988 2.2e-72 S Putative HNHc nuclease
HGEILGHP_00989 1.3e-22 ssb L Single-strand binding protein family
HGEILGHP_00990 2.6e-53 ybl78 L DnaD domain protein
HGEILGHP_00991 1.2e-39 pi346 L IstB-like ATP binding protein
HGEILGHP_00995 7.2e-194 L Belongs to the 'phage' integrase family
HGEILGHP_00996 1.7e-122 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HGEILGHP_00997 6.4e-07 S regulation of transcription, DNA-dependent
HGEILGHP_00998 7.6e-29
HGEILGHP_01000 9.1e-81 Q DNA (cytosine-5-)-methyltransferase activity
HGEILGHP_01002 1.8e-29 rusA L Endodeoxyribonuclease RusA
HGEILGHP_01005 1.5e-11
HGEILGHP_01007 1.2e-19
HGEILGHP_01008 3e-76 xtmA L Terminase small subunit
HGEILGHP_01009 4.1e-218 S Terminase-like family
HGEILGHP_01010 5e-215 S Phage portal protein, SPP1 Gp6-like
HGEILGHP_01011 4.3e-152 S Phage Mu protein F like protein
HGEILGHP_01012 3.8e-50 S Domain of unknown function (DUF4355)
HGEILGHP_01013 3.2e-54
HGEILGHP_01014 1e-166 S Phage major capsid protein E
HGEILGHP_01015 3.6e-35
HGEILGHP_01016 3.9e-57
HGEILGHP_01017 2.5e-79
HGEILGHP_01018 4.6e-53
HGEILGHP_01019 1.7e-71 S Phage tail tube protein, TTP
HGEILGHP_01020 5.3e-58
HGEILGHP_01021 7.5e-32
HGEILGHP_01022 0.0 M Phage tail tape measure protein TP901
HGEILGHP_01023 8.4e-52
HGEILGHP_01024 8.7e-229 L transposase, IS605 OrfB family
HGEILGHP_01025 2.8e-76 tlpA2 L Transposase IS200 like
HGEILGHP_01026 1.1e-33
HGEILGHP_01028 6.8e-61 rusA L Endodeoxyribonuclease RusA
HGEILGHP_01031 2.5e-32 V NUMOD4 motif
HGEILGHP_01033 7.7e-80 Q DNA (cytosine-5-)-methyltransferase activity
HGEILGHP_01034 6.3e-22
HGEILGHP_01036 6.6e-57 S VRR_NUC
HGEILGHP_01038 4.7e-124 S Virulence-associated protein E
HGEILGHP_01039 4.9e-84 S Bifunctional DNA primase/polymerase, N-terminal
HGEILGHP_01040 5.6e-34
HGEILGHP_01041 1.4e-87 L AAA domain
HGEILGHP_01042 3.3e-08 S Helix-turn-helix domain
HGEILGHP_01043 1.2e-157 res L Helicase C-terminal domain protein
HGEILGHP_01044 5.4e-33 S Siphovirus Gp157
HGEILGHP_01050 5.5e-24 K Helix-turn-helix XRE-family like proteins
HGEILGHP_01051 2.7e-65 K Cro/C1-type HTH DNA-binding domain
HGEILGHP_01052 9.8e-74 E IrrE N-terminal-like domain
HGEILGHP_01054 9.5e-20
HGEILGHP_01056 8e-10
HGEILGHP_01057 1.6e-93 L Belongs to the 'phage' integrase family
HGEILGHP_01058 6e-238 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HGEILGHP_01059 4.2e-155 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGEILGHP_01060 1.9e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
HGEILGHP_01061 1.2e-219 patA 2.6.1.1 E Aminotransferase
HGEILGHP_01062 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HGEILGHP_01063 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HGEILGHP_01064 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HGEILGHP_01065 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HGEILGHP_01066 4.1e-144 recO L Involved in DNA repair and RecF pathway recombination
HGEILGHP_01067 7.6e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGEILGHP_01068 4.2e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HGEILGHP_01069 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGEILGHP_01070 2.9e-182 phoH T phosphate starvation-inducible protein PhoH
HGEILGHP_01071 3.9e-168 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HGEILGHP_01072 6.9e-80 bioY S BioY family
HGEILGHP_01073 1.8e-259 argH 4.3.2.1 E argininosuccinate lyase
HGEILGHP_01074 3.5e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HGEILGHP_01075 4.9e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HGEILGHP_01076 3.8e-70 yqeY S YqeY-like protein
HGEILGHP_01077 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HGEILGHP_01078 1e-260 glnPH2 P ABC transporter permease
HGEILGHP_01079 2.9e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGEILGHP_01080 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HGEILGHP_01081 3.2e-166 yniA G Phosphotransferase enzyme family
HGEILGHP_01082 8.3e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HGEILGHP_01083 6.9e-27
HGEILGHP_01086 7.6e-266 S Uncharacterized protein conserved in bacteria (DUF2252)
HGEILGHP_01087 3.1e-292 L PFAM plasmid pRiA4b ORF-3 family protein
HGEILGHP_01088 1e-206 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HGEILGHP_01089 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGEILGHP_01090 7e-164 mleR K LysR family
HGEILGHP_01091 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HGEILGHP_01092 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HGEILGHP_01093 4.8e-268 frdC 1.3.5.4 C FAD binding domain
HGEILGHP_01094 3.7e-252 yflS P Sodium:sulfate symporter transmembrane region
HGEILGHP_01095 2.8e-157 mleR K LysR family
HGEILGHP_01096 3e-251 yjjP S Putative threonine/serine exporter
HGEILGHP_01097 1.9e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
HGEILGHP_01098 3.4e-272 emrY EGP Major facilitator Superfamily
HGEILGHP_01099 1.5e-183 I Alpha beta
HGEILGHP_01100 1.2e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HGEILGHP_01101 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGEILGHP_01103 6.8e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HGEILGHP_01104 3e-120 S Domain of unknown function (DUF4811)
HGEILGHP_01105 4.7e-269 lmrB EGP Major facilitator Superfamily
HGEILGHP_01106 5.2e-75 merR K MerR HTH family regulatory protein
HGEILGHP_01107 6.1e-55
HGEILGHP_01108 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGEILGHP_01109 6.1e-216 S CAAX protease self-immunity
HGEILGHP_01110 8e-109 glnP P ABC transporter permease
HGEILGHP_01111 5.4e-110 gluC P ABC transporter permease
HGEILGHP_01112 7.5e-152 glnH ET ABC transporter
HGEILGHP_01113 1.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGEILGHP_01114 5.5e-83 usp1 T Belongs to the universal stress protein A family
HGEILGHP_01115 2.2e-109 S VIT family
HGEILGHP_01116 5e-117 S membrane
HGEILGHP_01117 1.7e-165 czcD P cation diffusion facilitator family transporter
HGEILGHP_01118 3.2e-121 sirR K iron dependent repressor
HGEILGHP_01119 7.9e-31 cspC K Cold shock protein
HGEILGHP_01120 4.3e-130 thrE S Putative threonine/serine exporter
HGEILGHP_01121 2.1e-82 S Threonine/Serine exporter, ThrE
HGEILGHP_01122 2.7e-120 lssY 3.6.1.27 I phosphatase
HGEILGHP_01123 4.6e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
HGEILGHP_01124 1.1e-275 lysP E amino acid
HGEILGHP_01125 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HGEILGHP_01131 3.3e-57 sip L Belongs to the 'phage' integrase family
HGEILGHP_01132 1.3e-17 S sequence-specific DNA binding
HGEILGHP_01133 2.7e-14
HGEILGHP_01134 1e-27
HGEILGHP_01136 2.7e-46 S calcium ion binding
HGEILGHP_01142 8.3e-179 S Hydrolases of the alpha beta superfamily
HGEILGHP_01143 2.7e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HGEILGHP_01144 4.4e-77 ctsR K Belongs to the CtsR family
HGEILGHP_01145 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HGEILGHP_01146 6.7e-110 K Bacterial regulatory proteins, tetR family
HGEILGHP_01147 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGEILGHP_01148 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGEILGHP_01149 8.3e-197 ykiI
HGEILGHP_01150 3.4e-118 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
HGEILGHP_01151 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGEILGHP_01152 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HGEILGHP_01153 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGEILGHP_01154 7.8e-35 L Transposase
HGEILGHP_01155 1.5e-07 T Toxin-antitoxin system, toxin component, MazF family
HGEILGHP_01157 5.9e-30
HGEILGHP_01159 0.0 snf 2.7.11.1 KL domain protein
HGEILGHP_01160 2.2e-142 ywqE 3.1.3.48 GM PHP domain protein
HGEILGHP_01161 1.7e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HGEILGHP_01162 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HGEILGHP_01163 2.1e-149
HGEILGHP_01164 1.2e-16 3.2.1.14 GH18
HGEILGHP_01165 4.3e-82 zur P Belongs to the Fur family
HGEILGHP_01166 2.2e-102 gmk2 2.7.4.8 F Guanylate kinase
HGEILGHP_01167 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HGEILGHP_01168 2.7e-255 yfnA E Amino Acid
HGEILGHP_01169 1.1e-234 EGP Sugar (and other) transporter
HGEILGHP_01170 4.3e-231
HGEILGHP_01171 8.6e-209 potD P ABC transporter
HGEILGHP_01172 5.5e-139 potC P ABC transporter permease
HGEILGHP_01173 1.3e-145 potB P ABC transporter permease
HGEILGHP_01174 1.7e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HGEILGHP_01175 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HGEILGHP_01176 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HGEILGHP_01177 0.0 pacL 3.6.3.8 P P-type ATPase
HGEILGHP_01178 7.6e-85 dps P Belongs to the Dps family
HGEILGHP_01179 8.6e-249 yagE E amino acid
HGEILGHP_01180 4.4e-115 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HGEILGHP_01181 1.3e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HGEILGHP_01182 2.8e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HGEILGHP_01183 1.2e-137 IQ KR domain
HGEILGHP_01184 3.3e-133 S membrane transporter protein
HGEILGHP_01185 3.5e-97 S ABC-type cobalt transport system, permease component
HGEILGHP_01186 9.9e-250 cbiO1 S ABC transporter, ATP-binding protein
HGEILGHP_01187 7.5e-115 P Cobalt transport protein
HGEILGHP_01188 1.6e-52 yvlA
HGEILGHP_01189 0.0 yjcE P Sodium proton antiporter
HGEILGHP_01190 3.8e-52 ypaA S Protein of unknown function (DUF1304)
HGEILGHP_01191 4e-189 D Alpha beta
HGEILGHP_01192 1e-72 K Transcriptional regulator
HGEILGHP_01193 3.5e-160
HGEILGHP_01194 2.1e-132 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGEILGHP_01195 1.4e-158 S Membrane transport protein
HGEILGHP_01196 1e-84 K FCD
HGEILGHP_01197 5.7e-29 1.6.5.5 C Zinc-binding dehydrogenase
HGEILGHP_01198 6.3e-64 1.6.5.5 C Zinc-binding dehydrogenase
HGEILGHP_01199 9.9e-39 1.6.5.5 C Zinc-binding dehydrogenase
HGEILGHP_01200 2.1e-255 G PTS system Galactitol-specific IIC component
HGEILGHP_01201 2.4e-212 EGP Major facilitator Superfamily
HGEILGHP_01202 8.8e-135 V ABC transporter
HGEILGHP_01203 2.8e-107
HGEILGHP_01204 1.8e-14
HGEILGHP_01205 7.1e-63
HGEILGHP_01206 8.7e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HGEILGHP_01207 5.1e-81 uspA T universal stress protein
HGEILGHP_01208 0.0 tetP J elongation factor G
HGEILGHP_01209 8.9e-167 GK ROK family
HGEILGHP_01210 2.2e-241 brnQ U Component of the transport system for branched-chain amino acids
HGEILGHP_01211 2.5e-138 aroD S Serine hydrolase (FSH1)
HGEILGHP_01212 1.7e-241 yagE E amino acid
HGEILGHP_01213 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HGEILGHP_01214 2.3e-133 gntR K UbiC transcription regulator-associated domain protein
HGEILGHP_01215 3.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HGEILGHP_01216 1.8e-259 S Uncharacterised protein family (UPF0236)
HGEILGHP_01217 2e-29 S Acyltransferase family
HGEILGHP_01219 3.6e-48 S Glycosyltransferase like family 2
HGEILGHP_01220 2.7e-28 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HGEILGHP_01221 1.1e-29 M PFAM Glycosyl transferase family 2
HGEILGHP_01222 1.2e-28 M Glycosyltransferase sugar-binding region containing DXD motif
HGEILGHP_01223 7.5e-73 cps2I S Psort location CytoplasmicMembrane, score
HGEILGHP_01225 6e-41 GT2,GT4 M Glycosyltransferase GT-D fold
HGEILGHP_01226 5.7e-66 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HGEILGHP_01227 2.4e-87 GT4 G Glycosyl transferase 4-like
HGEILGHP_01228 4.5e-46 capM M Bacterial sugar transferase
HGEILGHP_01229 1.7e-107 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HGEILGHP_01230 1.3e-97 epsB M biosynthesis protein
HGEILGHP_01231 3.8e-159 L hmm pf00665
HGEILGHP_01232 3.4e-121 L Helix-turn-helix domain
HGEILGHP_01234 4e-49 yrvD S Pfam:DUF1049
HGEILGHP_01235 1.4e-150 3.1.3.102, 3.1.3.104 S hydrolase
HGEILGHP_01236 2.1e-90 ntd 2.4.2.6 F Nucleoside
HGEILGHP_01237 3.4e-21
HGEILGHP_01238 6.1e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HGEILGHP_01239 4.7e-114 yviA S Protein of unknown function (DUF421)
HGEILGHP_01240 2.6e-71 S Protein of unknown function (DUF3290)
HGEILGHP_01241 1.3e-41 ybaN S Protein of unknown function (DUF454)
HGEILGHP_01242 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGEILGHP_01243 3.6e-149 endA V DNA/RNA non-specific endonuclease
HGEILGHP_01244 8.7e-254 yifK E Amino acid permease
HGEILGHP_01246 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGEILGHP_01247 1.2e-230 N Uncharacterized conserved protein (DUF2075)
HGEILGHP_01248 1e-122 S SNARE associated Golgi protein
HGEILGHP_01249 0.0 uvrA3 L excinuclease ABC, A subunit
HGEILGHP_01250 2.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGEILGHP_01251 6e-56 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGEILGHP_01252 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HGEILGHP_01253 2.8e-135 S DUF218 domain
HGEILGHP_01254 0.0 ubiB S ABC1 family
HGEILGHP_01255 1.9e-245 yhdP S Transporter associated domain
HGEILGHP_01256 5e-75 copY K Copper transport repressor CopY TcrY
HGEILGHP_01257 2.4e-243 EGP Major facilitator Superfamily
HGEILGHP_01258 4.5e-74 yeaL S UPF0756 membrane protein
HGEILGHP_01259 8.6e-80 yphH S Cupin domain
HGEILGHP_01260 9e-41 K Transcriptional regulator
HGEILGHP_01261 6.7e-167 1.1.1.346 C Aldo keto reductase
HGEILGHP_01262 3.3e-37 gcvR T Belongs to the UPF0237 family
HGEILGHP_01263 4.8e-82 XK27_08635 S UPF0210 protein
HGEILGHP_01264 1.3e-140 XK27_08635 S UPF0210 protein
HGEILGHP_01265 1.8e-95 K Acetyltransferase (GNAT) domain
HGEILGHP_01266 1.2e-160 S Alpha beta hydrolase
HGEILGHP_01267 9.8e-48 gspA M family 8
HGEILGHP_01268 4e-85 gspA M family 8
HGEILGHP_01269 1.9e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HGEILGHP_01270 9.4e-94
HGEILGHP_01271 3.2e-161 degV S EDD domain protein, DegV family
HGEILGHP_01272 0.0 FbpA K Fibronectin-binding protein
HGEILGHP_01273 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HGEILGHP_01274 1.1e-206 carA 6.3.5.5 F Belongs to the CarA family
HGEILGHP_01275 4.2e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HGEILGHP_01276 2e-71 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGEILGHP_01277 1.5e-65 esbA S Family of unknown function (DUF5322)
HGEILGHP_01278 4e-71 rnhA 3.1.26.4 L Ribonuclease HI
HGEILGHP_01279 1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HGEILGHP_01280 1.1e-83 F Belongs to the NrdI family
HGEILGHP_01281 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HGEILGHP_01282 7.5e-103 ypsA S Belongs to the UPF0398 family
HGEILGHP_01283 2.4e-115 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HGEILGHP_01284 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HGEILGHP_01285 5.7e-161 EG EamA-like transporter family
HGEILGHP_01286 1.4e-122 dnaD L DnaD domain protein
HGEILGHP_01287 1.5e-86 ypmB S Protein conserved in bacteria
HGEILGHP_01288 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HGEILGHP_01289 5.3e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HGEILGHP_01290 2.7e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HGEILGHP_01291 4.6e-213 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HGEILGHP_01292 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HGEILGHP_01293 3.8e-87 S Protein of unknown function (DUF1440)
HGEILGHP_01294 0.0 rafA 3.2.1.22 G alpha-galactosidase
HGEILGHP_01295 2e-191 galR K Periplasmic binding protein-like domain
HGEILGHP_01296 4.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HGEILGHP_01297 1.9e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGEILGHP_01298 4.5e-124 lrgB M LrgB-like family
HGEILGHP_01299 1.9e-66 lrgA S LrgA family
HGEILGHP_01300 9.2e-130 lytT K response regulator receiver
HGEILGHP_01301 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HGEILGHP_01302 3.4e-147 f42a O Band 7 protein
HGEILGHP_01303 7e-264 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HGEILGHP_01304 1.2e-154 yitU 3.1.3.104 S hydrolase
HGEILGHP_01305 9.2e-39 S Cytochrome B5
HGEILGHP_01306 2e-112 nreC K PFAM regulatory protein LuxR
HGEILGHP_01307 1e-159 hipB K Helix-turn-helix
HGEILGHP_01308 4.7e-57 yitW S Iron-sulfur cluster assembly protein
HGEILGHP_01309 3e-270 sufB O assembly protein SufB
HGEILGHP_01310 5.5e-80 nifU C SUF system FeS assembly protein, NifU family
HGEILGHP_01311 3.6e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGEILGHP_01312 1.1e-239 sufD O FeS assembly protein SufD
HGEILGHP_01313 6.5e-145 sufC O FeS assembly ATPase SufC
HGEILGHP_01314 4.2e-32 feoA P FeoA domain
HGEILGHP_01315 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HGEILGHP_01316 8.3e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HGEILGHP_01317 6.5e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGEILGHP_01318 1.2e-64 ydiI Q Thioesterase superfamily
HGEILGHP_01319 1.6e-108 yvrI K RNA polymerase sigma factor, sigma-70 family
HGEILGHP_01320 1.3e-154 G Transporter, major facilitator family protein
HGEILGHP_01321 0.0 S Bacterial membrane protein YfhO
HGEILGHP_01322 1.9e-103 T Ion transport 2 domain protein
HGEILGHP_01323 3.9e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HGEILGHP_01324 1.1e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HGEILGHP_01325 1.2e-95 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HGEILGHP_01326 1e-182 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGEILGHP_01327 3.1e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HGEILGHP_01329 0.0 L PLD-like domain
HGEILGHP_01330 3e-16
HGEILGHP_01333 3.9e-66 mrr L restriction endonuclease
HGEILGHP_01334 2.2e-229 L Integrase core domain
HGEILGHP_01335 1.3e-97 GT2,GT4 LM gp58-like protein
HGEILGHP_01337 4.8e-12
HGEILGHP_01338 3.6e-18 S Bacteriophage holin family
HGEILGHP_01339 2e-185 M lysozyme activity
HGEILGHP_01340 8.8e-15 GT2,GT4 LM gp58-like protein
HGEILGHP_01341 3.3e-64 S Phage tail protein
HGEILGHP_01342 1e-143 S peptidoglycan catabolic process
HGEILGHP_01343 4.6e-20
HGEILGHP_01344 1.4e-45 S Pfam:Phage_TAC_12
HGEILGHP_01345 1.9e-85 S Phage major tail protein 2
HGEILGHP_01346 1.3e-42
HGEILGHP_01347 5.3e-43 S exonuclease activity
HGEILGHP_01348 4.6e-17
HGEILGHP_01349 1.2e-46 S Phage gp6-like head-tail connector protein
HGEILGHP_01350 2.6e-115
HGEILGHP_01351 7.3e-64 S aminoacyl-tRNA ligase activity
HGEILGHP_01353 5.9e-141 S Phage Mu protein F like protein
HGEILGHP_01354 1.4e-206 S Phage portal protein, SPP1 Gp6-like
HGEILGHP_01355 2.3e-216 S Phage terminase, large subunit
HGEILGHP_01356 2.2e-62 L Terminase small subunit
HGEILGHP_01358 3.4e-77 arpU S Phage transcriptional regulator, ArpU family
HGEILGHP_01363 1.9e-12
HGEILGHP_01367 3.2e-83 Q DNA (cytosine-5-)-methyltransferase activity
HGEILGHP_01368 2.7e-58 S VRR_NUC
HGEILGHP_01370 8.8e-234 S Virulence-associated protein E
HGEILGHP_01371 5.5e-144 S Bifunctional DNA primase/polymerase, N-terminal
HGEILGHP_01372 1.1e-92
HGEILGHP_01373 9.3e-141 L AAA domain
HGEILGHP_01374 1.9e-253 res L Helicase C-terminal domain protein
HGEILGHP_01375 8.3e-79 S Siphovirus Gp157
HGEILGHP_01377 8.4e-31
HGEILGHP_01380 7e-37
HGEILGHP_01381 8.8e-08 cro K Helix-turn-helix XRE-family like proteins
HGEILGHP_01382 5.9e-15 3.4.21.88 K Helix-turn-helix
HGEILGHP_01383 5.4e-19 E Pfam:DUF955
HGEILGHP_01384 3.2e-28 S Bacterial PH domain
HGEILGHP_01385 3.3e-18
HGEILGHP_01386 2.3e-212 L Belongs to the 'phage' integrase family
HGEILGHP_01394 2.1e-72 L Integrase core domain
HGEILGHP_01395 1.8e-226 S amidohydrolase
HGEILGHP_01396 2.4e-21 S amidohydrolase
HGEILGHP_01398 1.6e-35 K LysR substrate binding domain
HGEILGHP_01400 1.9e-07 yiiE S Protein of unknown function (DUF1211)
HGEILGHP_01402 1.2e-160 S reductase
HGEILGHP_01403 4.8e-90 2.3.1.183 M Acetyltransferase GNAT family
HGEILGHP_01404 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HGEILGHP_01405 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
HGEILGHP_01406 8.1e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGEILGHP_01407 0.0 asnB 6.3.5.4 E Asparagine synthase
HGEILGHP_01408 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HGEILGHP_01409 3.6e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGEILGHP_01410 1.3e-129 jag S R3H domain protein
HGEILGHP_01411 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HGEILGHP_01412 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HGEILGHP_01413 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HGEILGHP_01414 1.9e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGEILGHP_01415 2.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HGEILGHP_01416 1.7e-34 yaaA S S4 domain protein YaaA
HGEILGHP_01417 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGEILGHP_01418 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGEILGHP_01419 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGEILGHP_01420 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HGEILGHP_01421 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HGEILGHP_01422 2.1e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGEILGHP_01423 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HGEILGHP_01424 2e-74 rplI J Binds to the 23S rRNA
HGEILGHP_01425 1.3e-233 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HGEILGHP_01426 2.6e-206 yttB EGP Major facilitator Superfamily
HGEILGHP_01427 1.7e-54
HGEILGHP_01428 4.3e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HGEILGHP_01429 3.9e-123 Z012_01130 S Fic/DOC family
HGEILGHP_01431 2.6e-71 K helix_turn_helix multiple antibiotic resistance protein
HGEILGHP_01432 4.8e-310 lmrA 3.6.3.44 V ABC transporter
HGEILGHP_01434 5.2e-130 K response regulator
HGEILGHP_01435 0.0 vicK 2.7.13.3 T Histidine kinase
HGEILGHP_01436 1.5e-247 yycH S YycH protein
HGEILGHP_01437 5.4e-150 yycI S YycH protein
HGEILGHP_01438 2.3e-153 vicX 3.1.26.11 S domain protein
HGEILGHP_01439 1.9e-218 htrA 3.4.21.107 O serine protease
HGEILGHP_01440 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HGEILGHP_01441 1.1e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HGEILGHP_01442 2.2e-96 S reductase
HGEILGHP_01443 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HGEILGHP_01444 7.5e-155 glcU U sugar transport
HGEILGHP_01445 9.4e-149 E Glyoxalase-like domain
HGEILGHP_01446 7.8e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGEILGHP_01447 5.7e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HGEILGHP_01448 6.3e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGEILGHP_01449 2.6e-129 V ABC transporter
HGEILGHP_01450 4.6e-214 bacI V MacB-like periplasmic core domain
HGEILGHP_01451 1.2e-38
HGEILGHP_01452 5.9e-51 M NlpC P60 family protein
HGEILGHP_01453 1.8e-230 S Putative peptidoglycan binding domain
HGEILGHP_01456 6e-188 2.7.13.3 T GHKL domain
HGEILGHP_01457 1.1e-133 K LytTr DNA-binding domain
HGEILGHP_01459 9e-250 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HGEILGHP_01461 2.9e-75 osmC O OsmC-like protein
HGEILGHP_01462 1.4e-181 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGEILGHP_01463 1.4e-220 patA 2.6.1.1 E Aminotransferase
HGEILGHP_01464 7.8e-32
HGEILGHP_01465 0.0 clpL O associated with various cellular activities
HGEILGHP_01466 1.7e-207 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HGEILGHP_01468 1.4e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
HGEILGHP_01469 3.6e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGEILGHP_01470 2.1e-166 cpsY K Transcriptional regulator, LysR family
HGEILGHP_01471 1.6e-215 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGEILGHP_01472 2.3e-150 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGEILGHP_01473 7.3e-155 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
HGEILGHP_01474 6.6e-56 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGEILGHP_01475 3.6e-56 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGEILGHP_01477 1.9e-220 L transposase IS116 IS110 IS902 family protein
HGEILGHP_01478 8.5e-151 L Transposase
HGEILGHP_01479 2.4e-250 pipD E Dipeptidase
HGEILGHP_01480 9.5e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HGEILGHP_01481 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGEILGHP_01483 7.5e-58
HGEILGHP_01484 1.2e-180 prmA J Ribosomal protein L11 methyltransferase
HGEILGHP_01485 1.4e-125 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HGEILGHP_01486 1e-51
HGEILGHP_01487 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGEILGHP_01488 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HGEILGHP_01489 6.8e-33 L PFAM Integrase catalytic region
HGEILGHP_01490 6.3e-57 yitW S Pfam:DUF59
HGEILGHP_01491 2.9e-195 moaA 4.1.99.22 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGEILGHP_01492 3.3e-15 K Transcriptional regulator, LacI family
HGEILGHP_01493 7.1e-86 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HGEILGHP_01494 1.5e-90 L Integrase
HGEILGHP_01495 1.4e-42
HGEILGHP_01496 3.4e-90 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HGEILGHP_01497 0.0 S SEC-C Motif Domain Protein
HGEILGHP_01498 8e-51
HGEILGHP_01499 2.4e-139 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HGEILGHP_01500 4.6e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGEILGHP_01501 4.7e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HGEILGHP_01502 9.4e-231 clcA_2 P Chloride transporter, ClC family
HGEILGHP_01503 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HGEILGHP_01504 1.8e-116 lssY 3.6.1.27 I Acid phosphatase homologues
HGEILGHP_01506 3.3e-08
HGEILGHP_01507 5.8e-180 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGEILGHP_01508 2.9e-226 mtnE 2.6.1.83 E Aminotransferase
HGEILGHP_01509 3e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HGEILGHP_01510 5.5e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGEILGHP_01511 9e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGEILGHP_01512 2e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGEILGHP_01513 5.7e-85 L PFAM transposase IS200-family protein
HGEILGHP_01514 1.9e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGEILGHP_01515 4.7e-102 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HGEILGHP_01516 6.1e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HGEILGHP_01517 1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HGEILGHP_01518 1.1e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGEILGHP_01519 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGEILGHP_01520 2.6e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGEILGHP_01521 3.6e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
HGEILGHP_01522 7.5e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGEILGHP_01523 5.9e-58 yabA L Involved in initiation control of chromosome replication
HGEILGHP_01524 1.3e-182 holB 2.7.7.7 L DNA polymerase III
HGEILGHP_01525 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HGEILGHP_01526 2.1e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGEILGHP_01527 9.7e-39 S Protein of unknown function (DUF2508)
HGEILGHP_01528 3.7e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGEILGHP_01529 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGEILGHP_01530 1.6e-279 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGEILGHP_01531 1e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HGEILGHP_01532 3.4e-35 nrdH O Glutaredoxin
HGEILGHP_01533 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGEILGHP_01534 1.3e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGEILGHP_01535 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HGEILGHP_01536 1.2e-135 S Putative adhesin
HGEILGHP_01537 3.6e-79 XK27_06920 S Protein of unknown function (DUF1700)
HGEILGHP_01538 1.1e-56 K transcriptional regulator PadR family
HGEILGHP_01539 3.9e-50 L Bacterial dnaA protein
HGEILGHP_01540 1.3e-160 L Transposase
HGEILGHP_01541 2.9e-47
HGEILGHP_01542 3.2e-95 S N-acetylmuramoyl-L-alanine amidase activity
HGEILGHP_01543 1.1e-74 S Bacteriophage holin family
HGEILGHP_01546 1.6e-92 S peptidoglycan catabolic process
HGEILGHP_01551 4e-58
HGEILGHP_01552 2.6e-74 S Metallo-beta-lactamase superfamily
HGEILGHP_01553 5e-52 K Psort location Cytoplasmic, score
HGEILGHP_01554 4.3e-19 yjdF S Protein of unknown function (DUF2992)
HGEILGHP_01555 2e-88 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HGEILGHP_01556 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HGEILGHP_01557 2.6e-195 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HGEILGHP_01558 0.0 dnaK O Heat shock 70 kDa protein
HGEILGHP_01559 2.7e-76 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGEILGHP_01560 1.2e-194 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HGEILGHP_01561 6.5e-63
HGEILGHP_01562 4.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HGEILGHP_01563 2.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGEILGHP_01564 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGEILGHP_01565 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGEILGHP_01566 4.5e-49 ylxQ J ribosomal protein
HGEILGHP_01567 2.3e-44 ylxR K Protein of unknown function (DUF448)
HGEILGHP_01568 1.2e-214 nusA K Participates in both transcription termination and antitermination
HGEILGHP_01569 9.4e-83 rimP J Required for maturation of 30S ribosomal subunits
HGEILGHP_01570 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGEILGHP_01571 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HGEILGHP_01572 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HGEILGHP_01573 9.9e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HGEILGHP_01574 4.8e-137 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGEILGHP_01575 3.7e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HGEILGHP_01576 2.5e-127 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HGEILGHP_01577 9.3e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGEILGHP_01578 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HGEILGHP_01579 7.7e-180 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGEILGHP_01580 7.1e-49 yazA L GIY-YIG catalytic domain protein
HGEILGHP_01581 8.3e-142 yabB 2.1.1.223 L Methyltransferase small domain
HGEILGHP_01582 7.8e-117 plsC 2.3.1.51 I Acyltransferase
HGEILGHP_01583 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HGEILGHP_01584 4.3e-34 ynzC S UPF0291 protein
HGEILGHP_01585 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGEILGHP_01586 8.9e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HGEILGHP_01587 2.5e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGEILGHP_01589 6.6e-89
HGEILGHP_01590 7.1e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGEILGHP_01591 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HGEILGHP_01592 1.9e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HGEILGHP_01593 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HGEILGHP_01594 4.7e-249 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGEILGHP_01595 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HGEILGHP_01597 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HGEILGHP_01598 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HGEILGHP_01599 4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGEILGHP_01600 8.2e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HGEILGHP_01601 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGEILGHP_01602 3.6e-160 S Tetratricopeptide repeat
HGEILGHP_01603 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGEILGHP_01604 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGEILGHP_01605 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HGEILGHP_01606 6.4e-145 holA 2.7.7.7 L DNA polymerase III delta subunit
HGEILGHP_01607 0.0 comEC S Competence protein ComEC
HGEILGHP_01608 4e-89 comEB 3.5.4.12 F ComE operon protein 2
HGEILGHP_01609 6.4e-79 comEA L Competence protein ComEA
HGEILGHP_01610 7.1e-200 ylbL T Belongs to the peptidase S16 family
HGEILGHP_01611 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGEILGHP_01612 3.8e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HGEILGHP_01613 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HGEILGHP_01614 2.7e-222 ftsW D Belongs to the SEDS family
HGEILGHP_01615 0.0 typA T GTP-binding protein TypA
HGEILGHP_01616 1.4e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HGEILGHP_01617 1.4e-47 yktA S Belongs to the UPF0223 family
HGEILGHP_01618 5.4e-275 lpdA 1.8.1.4 C Dehydrogenase
HGEILGHP_01619 4.6e-228 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HGEILGHP_01620 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HGEILGHP_01621 9.8e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HGEILGHP_01622 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HGEILGHP_01623 4.8e-79
HGEILGHP_01624 9.8e-32 ykzG S Belongs to the UPF0356 family
HGEILGHP_01625 5.1e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HGEILGHP_01626 5.7e-29
HGEILGHP_01627 1.8e-124 mltD CBM50 M NlpC P60 family protein
HGEILGHP_01629 6.5e-57
HGEILGHP_01630 1.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HGEILGHP_01631 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGEILGHP_01632 1.3e-218 patA 2.6.1.1 E Aminotransferase
HGEILGHP_01633 2.5e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HGEILGHP_01634 5.3e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGEILGHP_01635 2.7e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HGEILGHP_01636 6.7e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HGEILGHP_01637 1.1e-250 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HGEILGHP_01638 1.6e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
HGEILGHP_01639 7.3e-186 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGEILGHP_01640 1.2e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGEILGHP_01641 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HGEILGHP_01642 9e-119 S Repeat protein
HGEILGHP_01643 1.7e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HGEILGHP_01644 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HGEILGHP_01645 2.8e-57 XK27_04120 S Putative amino acid metabolism
HGEILGHP_01646 5.4e-217 iscS 2.8.1.7 E Aminotransferase class V
HGEILGHP_01647 6.5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGEILGHP_01649 4.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HGEILGHP_01650 4.2e-32 cspA K Cold shock protein
HGEILGHP_01651 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGEILGHP_01652 1.9e-42 divIVA D DivIVA domain protein
HGEILGHP_01653 2.3e-142 ylmH S S4 domain protein
HGEILGHP_01654 3.2e-40 yggT S YGGT family
HGEILGHP_01655 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HGEILGHP_01656 6.9e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGEILGHP_01657 3.3e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HGEILGHP_01658 3e-140 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HGEILGHP_01659 8.6e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGEILGHP_01660 1.7e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGEILGHP_01661 6.4e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGEILGHP_01662 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HGEILGHP_01663 1.5e-56 ftsL D Cell division protein FtsL
HGEILGHP_01664 9.4e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HGEILGHP_01665 3.1e-77 mraZ K Belongs to the MraZ family
HGEILGHP_01666 7.6e-136 L Transposase
HGEILGHP_01667 8.5e-281 O Arylsulfotransferase (ASST)
HGEILGHP_01668 3.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGEILGHP_01669 1e-153
HGEILGHP_01670 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGEILGHP_01671 5.7e-244 purD 6.3.4.13 F Belongs to the GARS family
HGEILGHP_01672 9.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HGEILGHP_01673 2.1e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGEILGHP_01674 2.6e-194 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HGEILGHP_01675 6.5e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGEILGHP_01676 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGEILGHP_01677 1.7e-125 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGEILGHP_01678 1.3e-35 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGEILGHP_01679 4.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HGEILGHP_01680 1.5e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGEILGHP_01681 3.2e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGEILGHP_01682 2.1e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGEILGHP_01683 1.4e-125 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HGEILGHP_01684 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HGEILGHP_01685 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HGEILGHP_01686 6.4e-177 K AI-2E family transporter
HGEILGHP_01687 1.4e-228 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HGEILGHP_01688 1.8e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HGEILGHP_01689 1.9e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGEILGHP_01690 2.7e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HGEILGHP_01691 1.1e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HGEILGHP_01692 7.6e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HGEILGHP_01693 8.6e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HGEILGHP_01694 1.7e-130 K LysR substrate binding domain
HGEILGHP_01695 9.6e-53 azlD S branched-chain amino acid
HGEILGHP_01696 2e-137 azlC E AzlC protein
HGEILGHP_01697 5.4e-201 hpk31 2.7.13.3 T Histidine kinase
HGEILGHP_01698 3.8e-125 K response regulator
HGEILGHP_01699 1.3e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGEILGHP_01700 4.7e-171 deoR K sugar-binding domain protein
HGEILGHP_01701 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HGEILGHP_01702 3.1e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HGEILGHP_01703 1.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGEILGHP_01704 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGEILGHP_01705 2e-135 XK27_01040 S Protein of unknown function (DUF1129)
HGEILGHP_01706 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HGEILGHP_01707 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
HGEILGHP_01708 1.7e-154 spo0J K Belongs to the ParB family
HGEILGHP_01709 3.9e-139 soj D Sporulation initiation inhibitor
HGEILGHP_01710 4.3e-151 noc K Belongs to the ParB family
HGEILGHP_01711 5e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HGEILGHP_01712 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HGEILGHP_01713 1.7e-170 rihC 3.2.2.1 F Nucleoside
HGEILGHP_01714 1.1e-217 nupG F Nucleoside transporter
HGEILGHP_01715 2.5e-221 cycA E Amino acid permease
HGEILGHP_01716 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HGEILGHP_01717 1.5e-264 glnP P ABC transporter
HGEILGHP_01718 8.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGEILGHP_01719 0.0 infB UW LPXTG-motif cell wall anchor domain protein
HGEILGHP_01720 1.8e-55 fhaB M Rib/alpha-like repeat
HGEILGHP_01721 7.1e-153 spoU 2.1.1.185 J Methyltransferase
HGEILGHP_01722 2.4e-48 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
HGEILGHP_01723 8.6e-23 pnuC H nicotinamide mononucleotide transporter
HGEILGHP_01724 2.1e-56 pnuC H nicotinamide mononucleotide transporter
HGEILGHP_01725 2.4e-50 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGEILGHP_01726 4.5e-163 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGEILGHP_01727 2.1e-100 ywlG S Belongs to the UPF0340 family
HGEILGHP_01728 5.4e-53 S ParE toxin of type II toxin-antitoxin system, parDE
HGEILGHP_01729 3.7e-35 D Antitoxin component of a toxin-antitoxin (TA) module
HGEILGHP_01730 1.8e-196 EGP Major facilitator Superfamily
HGEILGHP_01731 1.2e-109 M Lysin motif
HGEILGHP_01732 1.1e-78
HGEILGHP_01733 1.7e-168 P CorA-like Mg2+ transporter protein
HGEILGHP_01734 5.6e-97 wecD3 K PFAM GCN5-related N-acetyltransferase
HGEILGHP_01735 3.9e-207 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HGEILGHP_01736 4.3e-13
HGEILGHP_01737 1.5e-77 S Domain of unknown function (DUF4767)
HGEILGHP_01738 2e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HGEILGHP_01739 2.1e-111 S Membrane
HGEILGHP_01740 4.9e-125 O Zinc-dependent metalloprotease
HGEILGHP_01741 2.6e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HGEILGHP_01742 3.8e-159 metQ_4 P Belongs to the nlpA lipoprotein family
HGEILGHP_01744 0.0 UW LPXTG-motif cell wall anchor domain protein
HGEILGHP_01745 0.0 UW LPXTG-motif cell wall anchor domain protein
HGEILGHP_01746 0.0 UW LPXTG-motif cell wall anchor domain protein
HGEILGHP_01747 4.9e-183 S Phosphotransferase system, EIIC
HGEILGHP_01748 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGEILGHP_01749 3.2e-165
HGEILGHP_01751 3.4e-25 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGEILGHP_01752 6.6e-23 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGEILGHP_01753 1.4e-95 2.3.1.128 K acetyltransferase
HGEILGHP_01754 6.4e-22
HGEILGHP_01755 1.7e-32
HGEILGHP_01756 6.7e-36
HGEILGHP_01757 7.7e-14 K Transcriptional regulator, HxlR family
HGEILGHP_01758 2.1e-216 P ammonium transporter
HGEILGHP_01759 2.1e-96 ureI S AmiS/UreI family transporter
HGEILGHP_01760 3.7e-48 ureA 3.5.1.5 E Urease, gamma subunit
HGEILGHP_01761 2.1e-69 ureB 3.5.1.5 E Urease beta subunit
HGEILGHP_01762 0.0 ureC 3.5.1.5 E Amidohydrolase family
HGEILGHP_01763 1.9e-77 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HGEILGHP_01764 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HGEILGHP_01765 1.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HGEILGHP_01766 3.2e-166 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HGEILGHP_01767 5.8e-183 nikMN P PDGLE domain
HGEILGHP_01768 8.5e-135 P Cobalt transport protein
HGEILGHP_01769 8.6e-136 cbiO P ABC transporter
HGEILGHP_01770 3e-133 K Transcriptional regulatory protein, C-terminal domain protein
HGEILGHP_01771 9.6e-158 pstS P Phosphate
HGEILGHP_01772 1.2e-152 pstC P probably responsible for the translocation of the substrate across the membrane
HGEILGHP_01773 1.4e-153 pstA P Phosphate transport system permease protein PstA
HGEILGHP_01774 2.3e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HGEILGHP_01775 2.1e-123 phoU P Plays a role in the regulation of phosphate uptake
HGEILGHP_01776 3.8e-135
HGEILGHP_01778 5e-243 ydaM M Glycosyl transferase
HGEILGHP_01779 3.5e-224 G Glycosyl hydrolases family 8
HGEILGHP_01780 2.3e-113 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HGEILGHP_01781 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HGEILGHP_01782 8.4e-238 ktrB P Potassium uptake protein
HGEILGHP_01783 1.4e-116 ktrA P domain protein
HGEILGHP_01784 3.5e-78 Q Methyltransferase
HGEILGHP_01785 3e-232 mntH P H( )-stimulated, divalent metal cation uptake system
HGEILGHP_01786 4e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HGEILGHP_01787 6.3e-168 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGEILGHP_01788 1e-85 S NADPH-dependent FMN reductase
HGEILGHP_01789 3.6e-172 MA20_14895 S Conserved hypothetical protein 698
HGEILGHP_01790 3.4e-166 L transposase, IS605 OrfB family
HGEILGHP_01791 5.5e-111 I alpha/beta hydrolase fold
HGEILGHP_01792 1.8e-126 lsa S ABC transporter
HGEILGHP_01793 1e-173 yfeX P Peroxidase
HGEILGHP_01794 2.2e-143 arcD S C4-dicarboxylate anaerobic carrier
HGEILGHP_01795 1.6e-97 arcD S C4-dicarboxylate anaerobic carrier
HGEILGHP_01796 2.1e-257 ytjP 3.5.1.18 E Dipeptidase
HGEILGHP_01797 1.7e-213 uhpT EGP Major facilitator Superfamily
HGEILGHP_01798 6.5e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HGEILGHP_01799 7.7e-130 ponA V Beta-lactamase enzyme family
HGEILGHP_01800 6.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HGEILGHP_01801 4.3e-74
HGEILGHP_01802 3.8e-30 L PFAM transposase IS200-family protein
HGEILGHP_01803 1.7e-236 lmrB EGP Major facilitator Superfamily
HGEILGHP_01804 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HGEILGHP_01805 2.2e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HGEILGHP_01806 3.1e-156 sufD O Uncharacterized protein family (UPF0051)
HGEILGHP_01807 5.1e-81 lytE M LysM domain protein
HGEILGHP_01808 0.0 oppD EP Psort location Cytoplasmic, score
HGEILGHP_01809 8.7e-93 lytE M LysM domain protein
HGEILGHP_01810 1.6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
HGEILGHP_01811 3.4e-148 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HGEILGHP_01812 8.4e-151 yeaE S Aldo keto
HGEILGHP_01813 2.7e-76 hsp O Belongs to the small heat shock protein (HSP20) family
HGEILGHP_01814 4e-281 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HGEILGHP_01815 4.5e-79 S Psort location Cytoplasmic, score
HGEILGHP_01816 2.9e-85 S Short repeat of unknown function (DUF308)
HGEILGHP_01817 1e-23
HGEILGHP_01818 2.8e-102 V VanZ like family
HGEILGHP_01819 1.3e-230 cycA E Amino acid permease
HGEILGHP_01820 4.3e-85 perR P Belongs to the Fur family
HGEILGHP_01821 6e-258 EGP Major facilitator Superfamily
HGEILGHP_01822 1.1e-95 tag 3.2.2.20 L glycosylase
HGEILGHP_01823 9.8e-214 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGEILGHP_01824 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGEILGHP_01825 4.9e-41
HGEILGHP_01826 3.8e-256 ytgP S Polysaccharide biosynthesis protein
HGEILGHP_01827 3.5e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGEILGHP_01828 3.7e-276 pepV 3.5.1.18 E dipeptidase PepV
HGEILGHP_01829 9.5e-86 uspA T Belongs to the universal stress protein A family
HGEILGHP_01830 3.3e-173 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HGEILGHP_01831 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HGEILGHP_01832 2.2e-113
HGEILGHP_01833 1.9e-186 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HGEILGHP_01834 2.2e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGEILGHP_01835 2.1e-32
HGEILGHP_01836 2.4e-116 S CAAX protease self-immunity
HGEILGHP_01837 5.6e-43
HGEILGHP_01839 1.7e-69
HGEILGHP_01840 2e-55 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGEILGHP_01841 1e-90 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HGEILGHP_01842 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HGEILGHP_01843 3.6e-230 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HGEILGHP_01844 1.3e-102 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HGEILGHP_01845 8.1e-213 folP 2.5.1.15 H dihydropteroate synthase
HGEILGHP_01846 6.7e-43
HGEILGHP_01847 3.3e-40
HGEILGHP_01849 1.6e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HGEILGHP_01850 1.8e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HGEILGHP_01851 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HGEILGHP_01852 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HGEILGHP_01853 9.4e-38 yheA S Belongs to the UPF0342 family
HGEILGHP_01854 2.6e-214 yhaO L Ser Thr phosphatase family protein
HGEILGHP_01855 0.0 L AAA domain
HGEILGHP_01856 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HGEILGHP_01858 8.3e-78 hit FG histidine triad
HGEILGHP_01859 4.8e-134 ecsA V ABC transporter, ATP-binding protein
HGEILGHP_01860 6.9e-215 ecsB U ABC transporter
HGEILGHP_01861 1.2e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HGEILGHP_01867 7.8e-183 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HGEILGHP_01868 3.8e-159 rrmA 2.1.1.187 H Methyltransferase
HGEILGHP_01869 6.7e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HGEILGHP_01870 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HGEILGHP_01871 1.2e-10 S Protein of unknown function (DUF4044)
HGEILGHP_01872 5e-57
HGEILGHP_01873 6.5e-47 L PFAM transposase IS200-family protein
HGEILGHP_01874 1.4e-37 pspC KT PspC domain protein
HGEILGHP_01875 3.5e-94 K Transcriptional regulator (TetR family)
HGEILGHP_01876 1.1e-218 V domain protein
HGEILGHP_01877 4.6e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGEILGHP_01879 6.6e-35 S Transglycosylase associated protein
HGEILGHP_01880 7e-234 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGEILGHP_01881 1.9e-126 G phosphoglycerate mutase
HGEILGHP_01882 8.8e-116 dedA S SNARE associated Golgi protein
HGEILGHP_01883 0.0 helD 3.6.4.12 L DNA helicase
HGEILGHP_01884 2.4e-245 nox C NADH oxidase
HGEILGHP_01885 2.2e-254 nox C NADH oxidase
HGEILGHP_01886 5.1e-159 EG EamA-like transporter family
HGEILGHP_01887 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HGEILGHP_01888 2.6e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HGEILGHP_01889 5e-226 S cog cog1373
HGEILGHP_01891 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HGEILGHP_01892 1.5e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HGEILGHP_01893 1.5e-247 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HGEILGHP_01894 1.2e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HGEILGHP_01896 1.9e-47
HGEILGHP_01897 5.7e-155 cylA V ABC transporter
HGEILGHP_01898 2.8e-146 cylB V ABC-2 type transporter
HGEILGHP_01899 1.3e-73 K LytTr DNA-binding domain
HGEILGHP_01900 1.5e-59 S Protein of unknown function (DUF3021)
HGEILGHP_01902 7.2e-175 L Plasmid pRiA4b ORF-3-like protein
HGEILGHP_01903 1.4e-15 1.6.5.2 S Flavodoxin-like fold
HGEILGHP_01904 3.8e-34 S ABC-2 family transporter protein
HGEILGHP_01905 1.3e-24 V ABC transporter, ATP-binding protein
HGEILGHP_01906 7.1e-29 V ABC transporter, ATP-binding protein
HGEILGHP_01907 5.8e-54 yqkB S Belongs to the HesB IscA family
HGEILGHP_01908 2.9e-20
HGEILGHP_01909 2e-19
HGEILGHP_01910 3.9e-34
HGEILGHP_01911 6.2e-36 S Protein of unknown function (DUF3021)
HGEILGHP_01912 7e-80 1.6.5.2 S NADPH-dependent FMN reductase
HGEILGHP_01913 7.7e-65 K Bacterial regulatory proteins, tetR family
HGEILGHP_01915 2.7e-158 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HGEILGHP_01916 1.9e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
HGEILGHP_01917 3.6e-271 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HGEILGHP_01918 1.2e-100 pncA Q Isochorismatase family
HGEILGHP_01919 1.6e-199 yegU O ADP-ribosylglycohydrolase
HGEILGHP_01920 6.5e-254 F Belongs to the purine-cytosine permease (2.A.39) family
HGEILGHP_01921 8.2e-165 G Belongs to the carbohydrate kinase PfkB family
HGEILGHP_01922 3e-37 hxlR K regulation of RNA biosynthetic process
HGEILGHP_01923 6.1e-241 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HGEILGHP_01924 2.9e-131 IQ Dehydrogenase reductase
HGEILGHP_01925 4.4e-38
HGEILGHP_01926 1.8e-113 ywnB S NAD(P)H-binding
HGEILGHP_01927 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
HGEILGHP_01928 4.5e-258 nhaC C Na H antiporter NhaC
HGEILGHP_01929 5.4e-184 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HGEILGHP_01931 9.2e-44 ydeN S Serine hydrolase
HGEILGHP_01932 1.3e-13 ydeN S Serine hydrolase
HGEILGHP_01933 4.5e-62 psiE S Phosphate-starvation-inducible E
HGEILGHP_01934 7.9e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGEILGHP_01936 1.3e-179 S Aldo keto reductase
HGEILGHP_01937 1.4e-84 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HGEILGHP_01938 0.0 L Helicase C-terminal domain protein
HGEILGHP_01940 3.7e-93 L hmm pf00665
HGEILGHP_01941 1.9e-127 L Helix-turn-helix domain
HGEILGHP_01942 5.5e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HGEILGHP_01943 3.3e-55 S Sugar efflux transporter for intercellular exchange
HGEILGHP_01944 2.1e-126
HGEILGHP_01945 8.2e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HGEILGHP_01946 7.2e-309 cadA P P-type ATPase
HGEILGHP_01947 4.9e-213 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HGEILGHP_01948 6.2e-76 K Transcriptional regulator
HGEILGHP_01949 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
HGEILGHP_01950 1.6e-109 proWZ P ABC transporter permease
HGEILGHP_01951 3.6e-140 proV E ABC transporter, ATP-binding protein
HGEILGHP_01952 4.5e-104 proW P ABC transporter, permease protein
HGEILGHP_01953 3.7e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HGEILGHP_01954 7.7e-216 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HGEILGHP_01955 3.1e-103 metI P ABC transporter permease
HGEILGHP_01956 1.8e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGEILGHP_01957 4.5e-152 metQ1 P Belongs to the nlpA lipoprotein family
HGEILGHP_01958 1.8e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HGEILGHP_01959 1.3e-221 norA EGP Major facilitator Superfamily
HGEILGHP_01960 4e-41 1.3.5.4 S FMN binding
HGEILGHP_01961 3.5e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGEILGHP_01962 4.3e-267 yfnA E amino acid
HGEILGHP_01963 1.3e-254 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HGEILGHP_01965 1e-79 L Transposase, IS116 IS110 IS902 family
HGEILGHP_01966 1.9e-197 clcA P chloride
HGEILGHP_01967 9.4e-201 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HGEILGHP_01968 0.0 helD 3.6.4.12 L DNA helicase
HGEILGHP_01969 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
HGEILGHP_01970 9.8e-180 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HGEILGHP_01971 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HGEILGHP_01972 1.8e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HGEILGHP_01973 7e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HGEILGHP_01974 1.6e-177
HGEILGHP_01975 1.8e-130 cobB K SIR2 family
HGEILGHP_01977 4e-161 yunF F Protein of unknown function DUF72
HGEILGHP_01978 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGEILGHP_01979 4.9e-156 tatD L hydrolase, TatD family
HGEILGHP_01980 2.5e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HGEILGHP_01981 3.8e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HGEILGHP_01982 6.8e-37 veg S Biofilm formation stimulator VEG
HGEILGHP_01983 1.2e-160 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGEILGHP_01984 2.5e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HGEILGHP_01985 5e-122 fhuC P ABC transporter
HGEILGHP_01986 2.3e-118 znuB U ABC 3 transport family
HGEILGHP_01987 2.6e-149 purR 2.4.2.7 F pur operon repressor
HGEILGHP_01988 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGEILGHP_01989 3.2e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGEILGHP_01990 2.1e-49
HGEILGHP_01991 8.4e-148 yxeH S hydrolase
HGEILGHP_01992 3.2e-269 ywfO S HD domain protein
HGEILGHP_01993 1.8e-145 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HGEILGHP_01994 3e-66 ywiB S Domain of unknown function (DUF1934)
HGEILGHP_01995 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HGEILGHP_01996 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HGEILGHP_01997 1.2e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGEILGHP_01998 4.6e-41 rpmE2 J Ribosomal protein L31
HGEILGHP_01999 1.7e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HGEILGHP_02000 2e-166 S Alpha/beta hydrolase of unknown function (DUF915)
HGEILGHP_02001 9.5e-124 srtA 3.4.22.70 M sortase family
HGEILGHP_02002 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HGEILGHP_02003 3.6e-159 3.2.1.55 GH51 G Right handed beta helix region
HGEILGHP_02004 7.5e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HGEILGHP_02005 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HGEILGHP_02006 7.8e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HGEILGHP_02007 6.8e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGEILGHP_02008 7e-93 lemA S LemA family
HGEILGHP_02009 1.5e-158 htpX O Belongs to the peptidase M48B family
HGEILGHP_02010 6.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HGEILGHP_02011 5.3e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HGEILGHP_02012 0.0 sprD D Domain of Unknown Function (DUF1542)
HGEILGHP_02013 6.5e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
HGEILGHP_02014 5.8e-252 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HGEILGHP_02015 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGEILGHP_02016 4.1e-231 dltB M MBOAT, membrane-bound O-acyltransferase family
HGEILGHP_02017 8e-293 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HGEILGHP_02019 5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HGEILGHP_02020 4.3e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGEILGHP_02021 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HGEILGHP_02022 7.5e-250 U Belongs to the purine-cytosine permease (2.A.39) family
HGEILGHP_02023 2.2e-240 codA 3.5.4.1 F cytosine deaminase
HGEILGHP_02024 2e-146 tesE Q hydratase
HGEILGHP_02025 3.4e-112 S (CBS) domain
HGEILGHP_02026 2.1e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HGEILGHP_02027 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGEILGHP_02028 2.1e-39 yabO J S4 domain protein
HGEILGHP_02029 6.6e-57 divIC D Septum formation initiator
HGEILGHP_02030 9.8e-67 yabR J RNA binding
HGEILGHP_02031 1.2e-255 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HGEILGHP_02032 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HGEILGHP_02033 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGEILGHP_02034 2e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGEILGHP_02035 7e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGEILGHP_02036 9.7e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HGEILGHP_02037 1.4e-52 entB 3.5.1.19 Q Isochorismatase family
HGEILGHP_02038 5.4e-46 L Transposase
HGEILGHP_02050 1.3e-19 WQ51_00220 K Helix-turn-helix domain
HGEILGHP_02051 5e-45 L Transposase
HGEILGHP_02052 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HGEILGHP_02053 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HGEILGHP_02054 2.8e-171 malR K Transcriptional regulator, LacI family
HGEILGHP_02055 7e-212 phbA 2.3.1.9 I Belongs to the thiolase family
HGEILGHP_02056 6.9e-256 malT G Major Facilitator
HGEILGHP_02057 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HGEILGHP_02058 1.9e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HGEILGHP_02059 9.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HGEILGHP_02060 3.3e-135 puuD S peptidase C26
HGEILGHP_02061 1.7e-167 yvgN C Aldo keto reductase
HGEILGHP_02062 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
HGEILGHP_02063 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HGEILGHP_02064 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
HGEILGHP_02065 1.1e-261 nox C NADH oxidase
HGEILGHP_02066 3.6e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HGEILGHP_02067 1.5e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGEILGHP_02068 8.8e-78
HGEILGHP_02069 1.4e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGEILGHP_02071 1.1e-13 steT_1 E amino acid
HGEILGHP_02072 6.7e-108 K Transcriptional regulator, TetR family
HGEILGHP_02073 5.4e-71
HGEILGHP_02074 2.4e-265 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HGEILGHP_02075 3.4e-264 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HGEILGHP_02076 1.2e-282 M protein which possibly mediates interactions of S.aureus with components of the extracellular matrix of higher eukaryotes
HGEILGHP_02077 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HGEILGHP_02078 1.5e-266 G Major Facilitator
HGEILGHP_02079 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HGEILGHP_02080 6.7e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HGEILGHP_02081 1.8e-259 G Major Facilitator
HGEILGHP_02082 1.7e-182 K Transcriptional regulator, LacI family
HGEILGHP_02083 7.7e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGEILGHP_02084 6.6e-99 nqr 1.5.1.36 S reductase
HGEILGHP_02085 3.3e-196 XK27_09615 S reductase
HGEILGHP_02086 2.9e-170 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HGEILGHP_02087 5.4e-283 pipD E Dipeptidase
HGEILGHP_02088 0.0 yfiC V ABC transporter
HGEILGHP_02089 2e-308 lmrA V ABC transporter, ATP-binding protein
HGEILGHP_02090 1.9e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGEILGHP_02091 3.5e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HGEILGHP_02092 1.7e-136
HGEILGHP_02093 1e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HGEILGHP_02094 4.3e-163 S AI-2E family transporter
HGEILGHP_02095 8.9e-133 XK27_07210 6.1.1.6 S B3 4 domain
HGEILGHP_02096 8.7e-78 yybA 2.3.1.57 K Transcriptional regulator
HGEILGHP_02097 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
HGEILGHP_02098 6.7e-90 GM epimerase
HGEILGHP_02099 1.4e-153 ypdB V (ABC) transporter
HGEILGHP_02100 2.1e-241 yhdP S Transporter associated domain
HGEILGHP_02101 1.3e-84 nrdI F Belongs to the NrdI family
HGEILGHP_02102 4.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
HGEILGHP_02103 1.4e-190 yeaN P Transporter, major facilitator family protein
HGEILGHP_02104 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGEILGHP_02105 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGEILGHP_02106 6.1e-39
HGEILGHP_02107 0.0 lacS G Transporter
HGEILGHP_02108 1.5e-80 uspA T universal stress protein
HGEILGHP_02109 2.5e-80 K AsnC family
HGEILGHP_02110 4e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HGEILGHP_02111 3.6e-95 dedA 3.1.3.1 S SNARE associated Golgi protein
HGEILGHP_02112 3.8e-179 galR K Transcriptional regulator
HGEILGHP_02113 4e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HGEILGHP_02114 4.5e-227 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HGEILGHP_02115 7.1e-178 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HGEILGHP_02116 8.3e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
HGEILGHP_02117 2e-91 yxkA S Phosphatidylethanolamine-binding protein
HGEILGHP_02118 9.1e-36
HGEILGHP_02119 5.9e-52
HGEILGHP_02120 5.3e-201
HGEILGHP_02121 3.7e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HGEILGHP_02122 4.4e-135 pnuC H nicotinamide mononucleotide transporter
HGEILGHP_02123 8.6e-156 ytbE 1.1.1.346 S Aldo keto reductase
HGEILGHP_02124 1.4e-124 K response regulator
HGEILGHP_02125 1.3e-179 T PhoQ Sensor
HGEILGHP_02126 3.7e-134 macB2 V ABC transporter, ATP-binding protein
HGEILGHP_02127 0.0 ysaB V FtsX-like permease family
HGEILGHP_02128 8.8e-153 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HGEILGHP_02129 1.9e-164 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HGEILGHP_02130 1.1e-52 K helix_turn_helix, mercury resistance
HGEILGHP_02131 8.7e-284 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGEILGHP_02132 7.6e-195 EGP Major facilitator Superfamily
HGEILGHP_02133 4.3e-86 ymdB S Macro domain protein
HGEILGHP_02134 1.9e-110 K Helix-turn-helix domain
HGEILGHP_02135 0.0 pepO 3.4.24.71 O Peptidase family M13
HGEILGHP_02136 3.9e-47
HGEILGHP_02137 1.1e-229 S Putative metallopeptidase domain
HGEILGHP_02138 1.1e-201 3.1.3.1 S associated with various cellular activities
HGEILGHP_02139 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HGEILGHP_02140 5.4e-65 yeaO S Protein of unknown function, DUF488
HGEILGHP_02142 7.1e-116 yrkL S Flavodoxin-like fold
HGEILGHP_02143 3.6e-54
HGEILGHP_02144 4.3e-18 S Domain of unknown function (DUF4767)
HGEILGHP_02145 1.3e-122 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HGEILGHP_02146 3.1e-49

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)