ORF_ID e_value Gene_name EC_number CAZy COGs Description
HFFHMGJP_00001 1.9e-194 lplA 6.3.1.20 H Lipoate-protein ligase
HFFHMGJP_00002 5.1e-81 uspA T universal stress protein
HFFHMGJP_00003 0.0 tetP J elongation factor G
HFFHMGJP_00004 8.9e-167 GK ROK family
HFFHMGJP_00005 1.8e-240 brnQ U Component of the transport system for branched-chain amino acids
HFFHMGJP_00006 7.7e-140 aroD S Serine hydrolase (FSH1)
HFFHMGJP_00007 2.8e-241 yagE E amino acid
HFFHMGJP_00008 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HFFHMGJP_00009 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HFFHMGJP_00010 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HFFHMGJP_00011 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HFFHMGJP_00012 2e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFHMGJP_00013 2.7e-48 yazA L GIY-YIG catalytic domain protein
HFFHMGJP_00014 1e-139 yabB 2.1.1.223 L Methyltransferase small domain
HFFHMGJP_00015 4.6e-117 plsC 2.3.1.51 I Acyltransferase
HFFHMGJP_00016 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HFFHMGJP_00017 1.3e-35 ynzC S UPF0291 protein
HFFHMGJP_00018 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFFHMGJP_00019 4e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HFFHMGJP_00020 5.1e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFFHMGJP_00022 4.8e-87
HFFHMGJP_00023 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HFFHMGJP_00024 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HFFHMGJP_00025 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HFFHMGJP_00026 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HFFHMGJP_00027 1.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HFFHMGJP_00028 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HFFHMGJP_00029 7.6e-09
HFFHMGJP_00030 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HFFHMGJP_00031 6.1e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HFFHMGJP_00032 1.1e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HFFHMGJP_00033 1.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HFFHMGJP_00034 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HFFHMGJP_00035 3e-162 S Tetratricopeptide repeat
HFFHMGJP_00036 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFFHMGJP_00037 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HFFHMGJP_00038 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HFFHMGJP_00039 4.5e-225 L Transposase
HFFHMGJP_00040 7.6e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
HFFHMGJP_00041 0.0 comEC S Competence protein ComEC
HFFHMGJP_00042 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
HFFHMGJP_00043 6.9e-81 comEA L Competence protein ComEA
HFFHMGJP_00044 7.9e-199 ylbL T Belongs to the peptidase S16 family
HFFHMGJP_00045 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HFFHMGJP_00046 1.4e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HFFHMGJP_00047 3.9e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HFFHMGJP_00048 1.2e-222 ftsW D Belongs to the SEDS family
HFFHMGJP_00049 0.0 typA T GTP-binding protein TypA
HFFHMGJP_00050 1.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HFFHMGJP_00051 3.3e-46 yktA S Belongs to the UPF0223 family
HFFHMGJP_00052 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
HFFHMGJP_00053 1.8e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HFFHMGJP_00054 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HFFHMGJP_00055 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HFFHMGJP_00056 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HFFHMGJP_00057 4e-81
HFFHMGJP_00058 9.8e-32 ykzG S Belongs to the UPF0356 family
HFFHMGJP_00059 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HFFHMGJP_00060 1.8e-82 L Helix-turn-helix domain
HFFHMGJP_00061 3.3e-145 L PFAM Integrase catalytic region
HFFHMGJP_00062 5.7e-29
HFFHMGJP_00063 3.6e-138 mltD CBM50 M NlpC P60 family protein
HFFHMGJP_00065 7.7e-58
HFFHMGJP_00066 2.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HFFHMGJP_00067 1.5e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HFFHMGJP_00068 1.5e-217 patA 2.6.1.1 E Aminotransferase
HFFHMGJP_00069 4.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HFFHMGJP_00070 1e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFFHMGJP_00071 8.5e-223 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HFFHMGJP_00072 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HFFHMGJP_00073 4.4e-247 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HFFHMGJP_00074 9.7e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
HFFHMGJP_00075 2.9e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HFFHMGJP_00076 2.3e-32 UW LPXTG-motif cell wall anchor domain protein
HFFHMGJP_00077 1.4e-132 infB UW LPXTG-motif cell wall anchor domain protein
HFFHMGJP_00078 1.5e-204 hsdM 2.1.1.72 V type I restriction-modification system
HFFHMGJP_00079 1.3e-22 3.1.21.3 V Type I restriction modification DNA specificity domain
HFFHMGJP_00080 1e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFFHMGJP_00081 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HFFHMGJP_00082 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HFFHMGJP_00083 1.5e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HFFHMGJP_00084 1.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HFFHMGJP_00085 1.5e-125 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HFFHMGJP_00086 4.9e-34 yaaA S S4 domain protein YaaA
HFFHMGJP_00087 1.1e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HFFHMGJP_00088 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFFHMGJP_00089 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HFFHMGJP_00090 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HFFHMGJP_00091 2.2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFFHMGJP_00092 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HFFHMGJP_00093 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HFFHMGJP_00094 2e-74 rplI J Binds to the 23S rRNA
HFFHMGJP_00095 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HFFHMGJP_00096 1.4e-204 yttB EGP Major facilitator Superfamily
HFFHMGJP_00097 2.5e-58
HFFHMGJP_00098 4.3e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HFFHMGJP_00099 1.2e-97 K DNA-binding helix-turn-helix protein
HFFHMGJP_00100 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_00102 1.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
HFFHMGJP_00103 3.3e-286 L Transposase IS66 family
HFFHMGJP_00104 7.7e-15 K HxlR-like helix-turn-helix
HFFHMGJP_00105 1.4e-70 M1-798 K Rhodanese Homology Domain
HFFHMGJP_00106 3.7e-24 CO cell redox homeostasis
HFFHMGJP_00107 1.2e-139 trxB 1.8.1.9 O Glucose inhibited division protein A
HFFHMGJP_00108 1e-95 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HFFHMGJP_00110 9.4e-39 trxA O Belongs to the thioredoxin family
HFFHMGJP_00111 9e-37 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HFFHMGJP_00112 5.6e-54 L Transposase
HFFHMGJP_00113 3.7e-57
HFFHMGJP_00114 1.2e-129 IQ Dehydrogenase reductase
HFFHMGJP_00115 2.9e-37
HFFHMGJP_00116 2.2e-114 ywnB S NAD(P)H-binding
HFFHMGJP_00117 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
HFFHMGJP_00118 1.4e-254 nhaC C Na H antiporter NhaC
HFFHMGJP_00119 1.6e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HFFHMGJP_00121 3.3e-100 ydeN S Serine hydrolase
HFFHMGJP_00122 2.7e-62 psiE S Phosphate-starvation-inducible E
HFFHMGJP_00123 1.2e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFFHMGJP_00125 1.6e-141 K helix_turn_helix, arabinose operon control protein
HFFHMGJP_00126 1.2e-85 S Membrane
HFFHMGJP_00127 0.0 rafA 3.2.1.22 G alpha-galactosidase
HFFHMGJP_00128 6.5e-176 S Aldo keto reductase
HFFHMGJP_00129 3.6e-77 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HFFHMGJP_00130 0.0 L Helicase C-terminal domain protein
HFFHMGJP_00132 1e-125 L Helix-turn-helix domain
HFFHMGJP_00133 3.2e-121 L hmm pf00665
HFFHMGJP_00134 1.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
HFFHMGJP_00136 4.6e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
HFFHMGJP_00137 5.7e-237 lmrB EGP Major facilitator Superfamily
HFFHMGJP_00138 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HFFHMGJP_00139 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HFFHMGJP_00140 3.6e-160 sufD O Uncharacterized protein family (UPF0051)
HFFHMGJP_00141 1.6e-42 lytE M LysM domain protein
HFFHMGJP_00142 0.0 oppD EP Psort location Cytoplasmic, score
HFFHMGJP_00143 1.1e-87 lytE M LysM domain protein
HFFHMGJP_00144 7.1e-149 xth 3.1.11.2 L exodeoxyribonuclease III
HFFHMGJP_00145 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HFFHMGJP_00146 2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
HFFHMGJP_00147 6.9e-153 yeaE S Aldo keto
HFFHMGJP_00148 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HFFHMGJP_00149 1.5e-283 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HFFHMGJP_00150 1.5e-79 S Psort location Cytoplasmic, score
HFFHMGJP_00151 7.7e-86 S Short repeat of unknown function (DUF308)
HFFHMGJP_00152 1e-23
HFFHMGJP_00153 4.1e-101 V VanZ like family
HFFHMGJP_00154 9e-232 cycA E Amino acid permease
HFFHMGJP_00155 4.3e-85 perR P Belongs to the Fur family
HFFHMGJP_00156 2.4e-259 EGP Major facilitator Superfamily
HFFHMGJP_00157 7.9e-94 tag 3.2.2.20 L glycosylase
HFFHMGJP_00158 1.6e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HFFHMGJP_00159 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFFHMGJP_00160 1.9e-40
HFFHMGJP_00161 6e-302 ytgP S Polysaccharide biosynthesis protein
HFFHMGJP_00162 7.7e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFFHMGJP_00163 2.8e-276 pepV 3.5.1.18 E dipeptidase PepV
HFFHMGJP_00164 9.5e-86 uspA T Belongs to the universal stress protein A family
HFFHMGJP_00165 8.6e-182 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFFHMGJP_00166 1.5e-115 dck 2.7.1.74 F deoxynucleoside kinase
HFFHMGJP_00167 5.9e-114
HFFHMGJP_00168 8.2e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HFFHMGJP_00169 1.8e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFFHMGJP_00170 6.9e-31
HFFHMGJP_00171 2e-115 S CAAX protease self-immunity
HFFHMGJP_00172 1.9e-43
HFFHMGJP_00174 4.9e-10 M LysM domain
HFFHMGJP_00175 7.2e-54
HFFHMGJP_00176 1.7e-142 S Domain of unknown function DUF1829
HFFHMGJP_00177 4.3e-73
HFFHMGJP_00178 5.3e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HFFHMGJP_00179 7e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HFFHMGJP_00180 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HFFHMGJP_00181 5.1e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFFHMGJP_00182 4.5e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HFFHMGJP_00183 4.8e-213 folP 2.5.1.15 H dihydropteroate synthase
HFFHMGJP_00184 1e-43
HFFHMGJP_00185 3.3e-40
HFFHMGJP_00187 5.4e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFFHMGJP_00188 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFFHMGJP_00189 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HFFHMGJP_00190 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HFFHMGJP_00191 9.4e-38 yheA S Belongs to the UPF0342 family
HFFHMGJP_00192 5.9e-219 yhaO L Ser Thr phosphatase family protein
HFFHMGJP_00193 0.0 L AAA domain
HFFHMGJP_00194 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HFFHMGJP_00196 8.3e-78 hit FG histidine triad
HFFHMGJP_00197 1.1e-135 ecsA V ABC transporter, ATP-binding protein
HFFHMGJP_00198 1.3e-218 ecsB U ABC transporter
HFFHMGJP_00199 6.9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HFFHMGJP_00200 1.5e-27 S YSIRK type signal peptide
HFFHMGJP_00201 0.0 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HFFHMGJP_00202 1e-125 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HFFHMGJP_00203 1.5e-116 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HFFHMGJP_00204 2.5e-183 iolS C Aldo keto reductase
HFFHMGJP_00205 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
HFFHMGJP_00206 7.5e-58 ytzB S Small secreted protein
HFFHMGJP_00207 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HFFHMGJP_00208 3.6e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFFHMGJP_00209 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HFFHMGJP_00210 1.9e-119 ybhL S Belongs to the BI1 family
HFFHMGJP_00211 3.2e-121 L hmm pf00665
HFFHMGJP_00212 1e-125 L Helix-turn-helix domain
HFFHMGJP_00213 5.8e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HFFHMGJP_00214 2.7e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFFHMGJP_00215 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
HFFHMGJP_00216 4.7e-114 yjbH Q Thioredoxin
HFFHMGJP_00217 2.3e-262 pipD E Dipeptidase
HFFHMGJP_00218 1.2e-202 coiA 3.6.4.12 S Competence protein
HFFHMGJP_00219 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HFFHMGJP_00220 3.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HFFHMGJP_00221 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HFFHMGJP_00241 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00242 5.4e-130 agrA K LytTr DNA-binding domain
HFFHMGJP_00243 1.9e-19 S Domain of unknown function (DUF4767)
HFFHMGJP_00245 3.8e-36 D nuclear chromosome segregation
HFFHMGJP_00246 5.8e-118
HFFHMGJP_00248 8.9e-09 S Domain of unknown function (DUF5067)
HFFHMGJP_00249 7.1e-24 S Domain of unknown function (DUF4767)
HFFHMGJP_00251 1.8e-151 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFFHMGJP_00252 2.9e-34 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFFHMGJP_00253 2.1e-115 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFFHMGJP_00254 2.2e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HFFHMGJP_00255 4.7e-255 yagE E amino acid
HFFHMGJP_00256 2.6e-85 dps P Belongs to the Dps family
HFFHMGJP_00257 0.0 pacL 3.6.3.8 P P-type ATPase
HFFHMGJP_00258 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HFFHMGJP_00259 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HFFHMGJP_00260 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HFFHMGJP_00261 1.3e-145 potB P ABC transporter permease
HFFHMGJP_00262 4.9e-140 potC P ABC transporter permease
HFFHMGJP_00263 1.6e-207 potD P ABC transporter
HFFHMGJP_00264 3.3e-231
HFFHMGJP_00265 7.2e-234 EGP Sugar (and other) transporter
HFFHMGJP_00266 3.9e-254 yfnA E Amino Acid
HFFHMGJP_00267 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HFFHMGJP_00268 1.3e-102 gmk2 2.7.4.8 F Guanylate kinase
HFFHMGJP_00269 1.5e-82 zur P Belongs to the Fur family
HFFHMGJP_00270 1.2e-16 3.2.1.14 GH18
HFFHMGJP_00271 3.7e-151
HFFHMGJP_00272 4.4e-39 pspC KT PspC domain protein
HFFHMGJP_00273 1.6e-94 K Transcriptional regulator (TetR family)
HFFHMGJP_00274 1.2e-217 V domain protein
HFFHMGJP_00276 1.9e-110 lssY 3.6.1.27 I Acid phosphatase homologues
HFFHMGJP_00277 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HFFHMGJP_00278 6.7e-229 clcA_2 P Chloride transporter, ClC family
HFFHMGJP_00279 7.2e-118 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HFFHMGJP_00280 1.1e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HFFHMGJP_00281 2.8e-64 L Belongs to the 'phage' integrase family
HFFHMGJP_00285 2.7e-17 S Short C-terminal domain
HFFHMGJP_00286 3.6e-69 3.4.21.88 K Peptidase S24-like
HFFHMGJP_00287 1.3e-09 K Helix-turn-helix XRE-family like proteins
HFFHMGJP_00292 2e-29
HFFHMGJP_00296 1.7e-152 recT L RecT family
HFFHMGJP_00297 5.3e-158 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HFFHMGJP_00298 4.6e-40 L Psort location Cytoplasmic, score
HFFHMGJP_00299 1.8e-56
HFFHMGJP_00309 5.4e-08
HFFHMGJP_00313 4.3e-33
HFFHMGJP_00318 7e-60 S HicB_like antitoxin of bacterial toxin-antitoxin system
HFFHMGJP_00319 5.9e-62 ps333 L Terminase small subunit
HFFHMGJP_00320 9e-173 ps334 S Terminase-like family
HFFHMGJP_00321 1.5e-183 S Phage portal protein, SPP1 Gp6-like
HFFHMGJP_00322 2.2e-99 S Phage Mu protein F like protein
HFFHMGJP_00323 6e-08 S Domain of unknown function (DUF4355)
HFFHMGJP_00324 1.5e-88 gpG
HFFHMGJP_00325 1.1e-38 S Phage gp6-like head-tail connector protein
HFFHMGJP_00326 1e-41
HFFHMGJP_00327 2.3e-50
HFFHMGJP_00328 2.6e-33
HFFHMGJP_00329 1.1e-76
HFFHMGJP_00330 3.6e-34 S Phage tail assembly chaperone protein, TAC
HFFHMGJP_00331 4e-14
HFFHMGJP_00332 1.5e-254 D NLP P60 protein
HFFHMGJP_00333 4.4e-155 S Phage tail protein
HFFHMGJP_00334 0.0 S Peptidase family M23
HFFHMGJP_00335 3.1e-34 spoIVFA GT2,GT4 D peptidase
HFFHMGJP_00338 2.1e-32 S GDSL-like Lipase/Acylhydrolase
HFFHMGJP_00339 2.1e-189
HFFHMGJP_00343 3.4e-31
HFFHMGJP_00344 7.7e-29 hol S COG5546 Small integral membrane protein
HFFHMGJP_00346 1e-36 S HNH endonuclease
HFFHMGJP_00347 3e-88 3.5.1.28 M Glycosyl hydrolases family 25
HFFHMGJP_00348 3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HFFHMGJP_00349 1.2e-51
HFFHMGJP_00350 0.0 S SEC-C Motif Domain Protein
HFFHMGJP_00351 2.9e-114 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HFFHMGJP_00352 5.5e-74
HFFHMGJP_00353 1.3e-176
HFFHMGJP_00354 2.2e-174 fecB P Periplasmic binding protein
HFFHMGJP_00355 1.2e-124 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HFFHMGJP_00356 1.3e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFFHMGJP_00357 3e-78 S Flavodoxin
HFFHMGJP_00358 9.1e-63 moaE 2.8.1.12 H MoaE protein
HFFHMGJP_00359 1.1e-31 moaD 2.8.1.12 H ThiS family
HFFHMGJP_00360 1.5e-217 narK P Transporter, major facilitator family protein
HFFHMGJP_00361 1.4e-143 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HFFHMGJP_00362 1.4e-173
HFFHMGJP_00363 3.6e-18
HFFHMGJP_00364 4.9e-114 nreC K PFAM regulatory protein LuxR
HFFHMGJP_00365 1.2e-183 comP 2.7.13.3 F Sensor histidine kinase
HFFHMGJP_00366 1.8e-41
HFFHMGJP_00367 7.6e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HFFHMGJP_00368 7.5e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HFFHMGJP_00369 1.1e-225 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HFFHMGJP_00370 1.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HFFHMGJP_00371 7.7e-183 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HFFHMGJP_00372 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HFFHMGJP_00373 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HFFHMGJP_00374 2.5e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HFFHMGJP_00375 3.3e-129 narI 1.7.5.1 C Nitrate reductase
HFFHMGJP_00376 6.5e-154 EG EamA-like transporter family
HFFHMGJP_00377 3.2e-118 L Integrase
HFFHMGJP_00378 1.2e-157 rssA S Phospholipase, patatin family
HFFHMGJP_00379 1e-23 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HFFHMGJP_00380 4.6e-202 xerS L Belongs to the 'phage' integrase family
HFFHMGJP_00382 2.8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFFHMGJP_00383 4.2e-77 marR K Transcriptional regulator, MarR family
HFFHMGJP_00384 3.7e-174 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HFFHMGJP_00385 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFFHMGJP_00386 5.5e-159 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HFFHMGJP_00387 1.7e-128 IQ reductase
HFFHMGJP_00388 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HFFHMGJP_00389 2.9e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HFFHMGJP_00390 1.1e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HFFHMGJP_00391 5.7e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HFFHMGJP_00392 9.3e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HFFHMGJP_00393 4.4e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HFFHMGJP_00394 7.1e-133 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HFFHMGJP_00401 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
HFFHMGJP_00402 3.9e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFFHMGJP_00403 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
HFFHMGJP_00404 5e-229 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HFFHMGJP_00405 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFFHMGJP_00406 2.7e-39 ptsH G phosphocarrier protein HPR
HFFHMGJP_00407 2.9e-27
HFFHMGJP_00408 0.0 clpE O Belongs to the ClpA ClpB family
HFFHMGJP_00409 1.7e-100 S Pfam:DUF3816
HFFHMGJP_00410 2.3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HFFHMGJP_00411 1.7e-23
HFFHMGJP_00412 2.9e-221
HFFHMGJP_00413 4.6e-138
HFFHMGJP_00414 0.0
HFFHMGJP_00415 6.4e-151 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HFFHMGJP_00416 8.6e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HFFHMGJP_00417 3.7e-102 fic D Fic/DOC family
HFFHMGJP_00418 7.3e-71
HFFHMGJP_00419 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HFFHMGJP_00420 2.5e-81 L nuclease
HFFHMGJP_00421 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HFFHMGJP_00422 6.2e-210 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HFFHMGJP_00423 1.7e-178 M Glycosyl hydrolases family 25
HFFHMGJP_00424 3.8e-142 ywqE 3.1.3.48 GM PHP domain protein
HFFHMGJP_00426 4e-37
HFFHMGJP_00427 1.5e-67 T Toxin-antitoxin system, toxin component, MazF family
HFFHMGJP_00429 3.4e-250 mmuP E amino acid
HFFHMGJP_00430 8.1e-171 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HFFHMGJP_00431 1.3e-70 O Preprotein translocase subunit SecB
HFFHMGJP_00433 2.3e-61
HFFHMGJP_00434 2.2e-28 S Protein of unknown function (DUF4065)
HFFHMGJP_00436 5.3e-130 1.6.5.2 GM NAD(P)H-binding
HFFHMGJP_00439 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
HFFHMGJP_00440 2.7e-296 L Transposase IS66 family
HFFHMGJP_00441 4.9e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFFHMGJP_00442 7.4e-165
HFFHMGJP_00443 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFFHMGJP_00444 2.3e-245 purD 6.3.4.13 F Belongs to the GARS family
HFFHMGJP_00445 1.5e-294 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HFFHMGJP_00446 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFFHMGJP_00447 1.5e-194 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HFFHMGJP_00448 4e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HFFHMGJP_00449 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFHMGJP_00450 9.8e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFHMGJP_00451 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFFHMGJP_00452 3.5e-129 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HFFHMGJP_00453 2.4e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFFHMGJP_00454 2.1e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFFHMGJP_00455 5.6e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HFFHMGJP_00456 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HFFHMGJP_00457 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HFFHMGJP_00458 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HFFHMGJP_00459 4.7e-172 K AI-2E family transporter
HFFHMGJP_00460 7.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HFFHMGJP_00461 5.3e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HFFHMGJP_00462 8.7e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HFFHMGJP_00463 1.3e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HFFHMGJP_00464 3.3e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HFFHMGJP_00465 2.8e-246 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HFFHMGJP_00466 8.6e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HFFHMGJP_00467 5.3e-140 K LysR substrate binding domain
HFFHMGJP_00468 3.6e-52 azlD S branched-chain amino acid
HFFHMGJP_00469 1.9e-140 azlC E AzlC protein
HFFHMGJP_00470 1.8e-201 hpk31 2.7.13.3 T Histidine kinase
HFFHMGJP_00471 3.8e-125 K response regulator
HFFHMGJP_00472 2e-208 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFFHMGJP_00473 1.4e-170 deoR K sugar-binding domain protein
HFFHMGJP_00474 1.5e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HFFHMGJP_00475 2.6e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HFFHMGJP_00476 2.4e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HFFHMGJP_00477 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HFFHMGJP_00478 4.5e-135 XK27_01040 S Protein of unknown function (DUF1129)
HFFHMGJP_00479 5.7e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HFFHMGJP_00480 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
HFFHMGJP_00481 6.5e-154 spo0J K Belongs to the ParB family
HFFHMGJP_00482 3.9e-139 soj D Sporulation initiation inhibitor
HFFHMGJP_00483 4.5e-148 noc K Belongs to the ParB family
HFFHMGJP_00484 3.3e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HFFHMGJP_00485 7.7e-163 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HFFHMGJP_00486 2.7e-171 rihC 3.2.2.1 F Nucleoside
HFFHMGJP_00487 1e-218 nupG F Nucleoside transporter
HFFHMGJP_00488 7.7e-223 cycA E Amino acid permease
HFFHMGJP_00489 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFFHMGJP_00490 1.2e-264 glnP P ABC transporter
HFFHMGJP_00491 2.5e-250 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HFFHMGJP_00492 1.4e-186 infB UW LPXTG-motif cell wall anchor domain protein
HFFHMGJP_00500 1.8e-133 L Belongs to the 'phage' integrase family
HFFHMGJP_00501 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HFFHMGJP_00503 1.4e-42 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HFFHMGJP_00504 5.4e-08 UW LPXTG-motif cell wall anchor domain protein
HFFHMGJP_00505 2.4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFFHMGJP_00506 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HFFHMGJP_00507 3.4e-118 S Repeat protein
HFFHMGJP_00508 8.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HFFHMGJP_00509 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HFFHMGJP_00510 7.5e-58 XK27_04120 S Putative amino acid metabolism
HFFHMGJP_00511 2.1e-216 iscS 2.8.1.7 E Aminotransferase class V
HFFHMGJP_00512 5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFFHMGJP_00514 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HFFHMGJP_00515 1.6e-31 cspA K Cold shock protein
HFFHMGJP_00516 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFFHMGJP_00517 1.9e-42 divIVA D DivIVA domain protein
HFFHMGJP_00518 2.3e-142 ylmH S S4 domain protein
HFFHMGJP_00519 3.2e-40 yggT S YGGT family
HFFHMGJP_00520 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HFFHMGJP_00521 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFFHMGJP_00522 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HFFHMGJP_00523 9.3e-150 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HFFHMGJP_00524 1.7e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HFFHMGJP_00525 2.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HFFHMGJP_00526 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HFFHMGJP_00527 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HFFHMGJP_00528 1.5e-56 ftsL D Cell division protein FtsL
HFFHMGJP_00529 1e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HFFHMGJP_00530 3.1e-77 mraZ K Belongs to the MraZ family
HFFHMGJP_00531 1.7e-57
HFFHMGJP_00532 1.2e-10 S Protein of unknown function (DUF4044)
HFFHMGJP_00533 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HFFHMGJP_00534 1e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HFFHMGJP_00535 4.5e-160 rrmA 2.1.1.187 H Methyltransferase
HFFHMGJP_00536 1.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HFFHMGJP_00540 2.1e-302 L Transposase
HFFHMGJP_00541 1.1e-53 L PFAM Integrase catalytic region
HFFHMGJP_00542 3.6e-92 L PFAM Integrase catalytic region
HFFHMGJP_00543 2.7e-296 S amidohydrolase
HFFHMGJP_00544 4.6e-125 S Alpha/beta hydrolase of unknown function (DUF915)
HFFHMGJP_00545 4.3e-146 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFHMGJP_00547 7e-161 S reductase
HFFHMGJP_00548 5.9e-88 2.3.1.183 M Acetyltransferase GNAT family
HFFHMGJP_00549 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HFFHMGJP_00550 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HFFHMGJP_00551 3.6e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFFHMGJP_00552 0.0 asnB 6.3.5.4 E Asparagine synthase
HFFHMGJP_00553 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HFFHMGJP_00554 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HFFHMGJP_00555 7.2e-133 jag S R3H domain protein
HFFHMGJP_00558 2.2e-302 L Transposase
HFFHMGJP_00559 2e-30
HFFHMGJP_00560 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HFFHMGJP_00561 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HFFHMGJP_00562 4.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HFFHMGJP_00563 1e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HFFHMGJP_00564 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HFFHMGJP_00565 3.1e-32 KT PspC domain protein
HFFHMGJP_00566 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HFFHMGJP_00567 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFFHMGJP_00568 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HFFHMGJP_00569 1.9e-116 comFC S Competence protein
HFFHMGJP_00570 1.3e-254 comFA L Helicase C-terminal domain protein
HFFHMGJP_00571 8.6e-108 yvyE 3.4.13.9 S YigZ family
HFFHMGJP_00572 1.4e-13 hxlR1 K transcriptional
HFFHMGJP_00573 1.9e-38 C nitroreductase
HFFHMGJP_00574 4.6e-62 EGP Major facilitator Superfamily
HFFHMGJP_00575 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00576 2.1e-302 L Transposase
HFFHMGJP_00577 0.0 uup S ABC transporter, ATP-binding protein
HFFHMGJP_00578 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HFFHMGJP_00580 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HFFHMGJP_00581 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HFFHMGJP_00582 1.8e-84 S Aminoacyl-tRNA editing domain
HFFHMGJP_00583 9.6e-305 ybeC E amino acid
HFFHMGJP_00584 0.0 ydaO E amino acid
HFFHMGJP_00585 9.2e-40
HFFHMGJP_00586 3.3e-68 rmaI K Transcriptional regulator
HFFHMGJP_00587 3.3e-133 EGP Major facilitator Superfamily
HFFHMGJP_00588 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00589 0.0 ilvD 4.2.1.9 EG Belongs to the IlvD Edd family
HFFHMGJP_00590 1.2e-39 S Iron-sulfur cluster assembly protein
HFFHMGJP_00591 3e-155 yocS S SBF-like CPA transporter family (DUF4137)
HFFHMGJP_00593 1.4e-119 azlC E azaleucine resistance protein AzlC
HFFHMGJP_00594 7.1e-50 azlD E Branched-chain amino acid transport
HFFHMGJP_00595 8.6e-119 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HFFHMGJP_00597 1.9e-149 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFFHMGJP_00598 3.9e-127 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HFFHMGJP_00599 5.2e-113 S GyrI-like small molecule binding domain
HFFHMGJP_00600 2.7e-123 yhiD S MgtC family
HFFHMGJP_00601 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFFHMGJP_00602 7.9e-196 V Beta-lactamase
HFFHMGJP_00603 8.8e-56 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HFFHMGJP_00604 1.1e-89 XK27_08850 J Aminoacyl-tRNA editing domain
HFFHMGJP_00605 3.1e-19 relB L Addiction module antitoxin, RelB DinJ family
HFFHMGJP_00606 8e-25
HFFHMGJP_00607 1.4e-120 K LytTr DNA-binding domain
HFFHMGJP_00608 6.8e-213 2.7.13.3 T GHKL domain
HFFHMGJP_00613 1.6e-120 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
HFFHMGJP_00614 5.8e-161 mleP3 S Membrane transport protein
HFFHMGJP_00615 3.3e-105 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFFHMGJP_00616 2.6e-51 K transcriptional
HFFHMGJP_00617 3.1e-119 T Transcriptional regulatory protein, C terminal
HFFHMGJP_00618 1.8e-232 T GHKL domain
HFFHMGJP_00619 3.1e-92 S Peptidase propeptide and YPEB domain
HFFHMGJP_00620 2.4e-225 4.4.1.8 E Aminotransferase, class I
HFFHMGJP_00621 4.4e-99 M Protein of unknown function (DUF3737)
HFFHMGJP_00622 8.6e-56 yphJ 4.1.1.44 S decarboxylase
HFFHMGJP_00623 1.3e-84 K Bacterial regulatory proteins, tetR family
HFFHMGJP_00624 3.8e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFFHMGJP_00625 2.3e-168 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HFFHMGJP_00626 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
HFFHMGJP_00627 3.5e-85 C Flavodoxin
HFFHMGJP_00628 8.1e-149 K Transcriptional regulator
HFFHMGJP_00629 7.5e-40 lacA S transferase hexapeptide repeat
HFFHMGJP_00630 6.2e-39 lacA S transferase hexapeptide repeat
HFFHMGJP_00631 2.5e-135 S Hydrolases of the alpha beta superfamily
HFFHMGJP_00632 3.5e-152 S Alpha beta hydrolase
HFFHMGJP_00633 7.9e-94 padC Q Phenolic acid decarboxylase
HFFHMGJP_00634 2.9e-93 padR K Virulence activator alpha C-term
HFFHMGJP_00635 4.7e-66 GM NAD(P)H-binding
HFFHMGJP_00636 3e-155 ypuA S Protein of unknown function (DUF1002)
HFFHMGJP_00637 1.5e-183 ansA 3.5.1.1 EJ L-asparaginase, type I
HFFHMGJP_00638 1.8e-132 K Transcriptional regulator
HFFHMGJP_00639 6.4e-162 akr5f 1.1.1.346 S reductase
HFFHMGJP_00640 5.3e-104 K Transcriptional regulator C-terminal region
HFFHMGJP_00641 2e-187 S membrane
HFFHMGJP_00642 2e-112 GM NAD(P)H-binding
HFFHMGJP_00643 1.1e-64 yneR
HFFHMGJP_00644 4.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HFFHMGJP_00645 2.4e-142 T EAL domain
HFFHMGJP_00646 6.8e-248 pgaC GT2 M Glycosyl transferase
HFFHMGJP_00647 7.3e-86
HFFHMGJP_00648 3.1e-193 2.7.7.65 T GGDEF domain
HFFHMGJP_00649 1.1e-121 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HFFHMGJP_00650 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HFFHMGJP_00651 4.9e-198 asnA 6.3.1.1 F aspartate--ammonia ligase
HFFHMGJP_00652 1.5e-92 folT S ECF transporter, substrate-specific component
HFFHMGJP_00653 0.0 pepN 3.4.11.2 E aminopeptidase
HFFHMGJP_00654 4.5e-112 ylbE GM NAD dependent epimerase dehydratase family protein
HFFHMGJP_00655 6.8e-256 pepC 3.4.22.40 E aminopeptidase
HFFHMGJP_00656 7.7e-211 EGP Major facilitator Superfamily
HFFHMGJP_00657 5.3e-237
HFFHMGJP_00658 3.1e-83 K Transcriptional regulator, HxlR family
HFFHMGJP_00659 2.4e-107 XK27_02070 S Nitroreductase family
HFFHMGJP_00660 2.5e-52 hxlR K Transcriptional regulator, HxlR family
HFFHMGJP_00661 7.8e-120 GM NmrA-like family
HFFHMGJP_00662 1.4e-77 elaA S Gnat family
HFFHMGJP_00663 2.4e-39 S Cytochrome B5
HFFHMGJP_00664 7e-09 S Cytochrome B5
HFFHMGJP_00665 1.6e-41 S Cytochrome B5
HFFHMGJP_00666 3.3e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
HFFHMGJP_00668 8e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFFHMGJP_00669 2.9e-241 E amino acid
HFFHMGJP_00670 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_00671 1.9e-58 M Collagen binding domain
HFFHMGJP_00672 2.7e-205 L Psort location Cytoplasmic, score
HFFHMGJP_00673 2.4e-33
HFFHMGJP_00674 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HFFHMGJP_00675 1.3e-69
HFFHMGJP_00676 3.3e-147
HFFHMGJP_00677 2e-62
HFFHMGJP_00678 8.7e-263 traK U TraM recognition site of TraD and TraG
HFFHMGJP_00680 7.4e-80
HFFHMGJP_00681 3.3e-88
HFFHMGJP_00682 1.8e-193 M CHAP domain
HFFHMGJP_00683 5.8e-221 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HFFHMGJP_00684 0.0 traE U AAA-like domain
HFFHMGJP_00685 8.1e-117
HFFHMGJP_00686 1.7e-36
HFFHMGJP_00687 2.7e-52 S Cag pathogenicity island, type IV secretory system
HFFHMGJP_00688 5.4e-107
HFFHMGJP_00689 2.1e-51
HFFHMGJP_00690 0.0 L MobA MobL family protein
HFFHMGJP_00691 3.2e-27
HFFHMGJP_00692 8.9e-41
HFFHMGJP_00693 4.1e-116 S protein conserved in bacteria
HFFHMGJP_00694 1.2e-25
HFFHMGJP_00695 1.1e-39 relB L Addiction module antitoxin, RelB DinJ family
HFFHMGJP_00696 1.2e-132 S Fic/DOC family
HFFHMGJP_00697 4e-27
HFFHMGJP_00698 2.2e-167 repA S Replication initiator protein A
HFFHMGJP_00699 8.5e-35
HFFHMGJP_00700 4.9e-148 D CobQ CobB MinD ParA nucleotide binding domain protein
HFFHMGJP_00701 1.3e-221 L Probable transposase
HFFHMGJP_00702 5.7e-17 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HFFHMGJP_00703 1.4e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HFFHMGJP_00704 2.1e-97 K Bacterial regulatory proteins, tetR family
HFFHMGJP_00705 3.3e-285 norB EGP Major Facilitator
HFFHMGJP_00708 3.7e-94 K Transcriptional regulator
HFFHMGJP_00709 1.8e-206 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HFFHMGJP_00710 3.2e-124 H ThiF family
HFFHMGJP_00711 3.4e-59 MA20_41110 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFFHMGJP_00712 8.2e-233 stp_1 EGP Major facilitator Superfamily
HFFHMGJP_00713 1.6e-102 tag 3.2.2.20 L glycosylase
HFFHMGJP_00714 9.4e-126 S Alpha/beta hydrolase of unknown function (DUF915)
HFFHMGJP_00715 1.5e-146 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFHMGJP_00716 2.4e-168 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HFFHMGJP_00717 1.3e-46 yiiE S Protein of unknown function (DUF1211)
HFFHMGJP_00718 2.8e-67 adhR K helix_turn_helix, mercury resistance
HFFHMGJP_00719 1.3e-52 K Transcriptional regulator
HFFHMGJP_00720 4e-67 C Flavodoxin
HFFHMGJP_00721 1.3e-19 darA C Flavodoxin
HFFHMGJP_00722 7.8e-69 C Flavodoxin
HFFHMGJP_00723 4e-87 P esterase
HFFHMGJP_00724 8.7e-46 fldA C Flavodoxin
HFFHMGJP_00725 2.6e-115 GM NmrA-like family
HFFHMGJP_00726 6.9e-147 C Aldo keto reductase
HFFHMGJP_00728 1.1e-101 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HFFHMGJP_00729 2.5e-197 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HFFHMGJP_00730 6.4e-24
HFFHMGJP_00731 8.5e-44 L 4.5 Transposon and IS
HFFHMGJP_00732 7.2e-155 L 4.5 Transposon and IS
HFFHMGJP_00733 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00734 1.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HFFHMGJP_00736 2e-219 S cog cog1373
HFFHMGJP_00737 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HFFHMGJP_00738 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFFHMGJP_00739 3e-159 EG EamA-like transporter family
HFFHMGJP_00740 5.9e-255 nox C NADH oxidase
HFFHMGJP_00741 1e-243 nox C NADH oxidase
HFFHMGJP_00742 0.0 helD 3.6.4.12 L DNA helicase
HFFHMGJP_00743 6.8e-116 dedA S SNARE associated Golgi protein
HFFHMGJP_00744 1.6e-125 3.1.3.73 G phosphoglycerate mutase
HFFHMGJP_00745 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFFHMGJP_00746 2e-31 S Transglycosylase associated protein
HFFHMGJP_00748 2.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFHMGJP_00749 2.3e-143 L PFAM Integrase catalytic region
HFFHMGJP_00750 3.3e-41 L Helix-turn-helix domain
HFFHMGJP_00752 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00753 1e-37
HFFHMGJP_00754 0.0 yhcA V ABC transporter, ATP-binding protein
HFFHMGJP_00755 6.3e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HFFHMGJP_00756 1.7e-172 hrtB V ABC transporter permease
HFFHMGJP_00757 2.6e-86 ygfC K transcriptional regulator (TetR family)
HFFHMGJP_00758 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HFFHMGJP_00759 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
HFFHMGJP_00760 5.6e-36
HFFHMGJP_00761 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HFFHMGJP_00763 1.2e-227 yxiO S Vacuole effluxer Atg22 like
HFFHMGJP_00764 1.5e-255 npp S type I phosphodiesterase nucleotide pyrophosphatase
HFFHMGJP_00765 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_00766 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00768 8.5e-170 1.1.1.346 C Aldo keto reductase
HFFHMGJP_00769 5.5e-161 K LysR substrate binding domain protein
HFFHMGJP_00770 7.2e-83 C Flavodoxin
HFFHMGJP_00771 1e-80 yphH S Cupin domain
HFFHMGJP_00772 4.5e-74 yeaL S UPF0756 membrane protein
HFFHMGJP_00773 9.6e-245 EGP Major facilitator Superfamily
HFFHMGJP_00774 1.9e-74 copY K Copper transport repressor CopY TcrY
HFFHMGJP_00775 8.5e-246 yhdP S Transporter associated domain
HFFHMGJP_00776 0.0 ubiB S ABC1 family
HFFHMGJP_00777 1.9e-144 S DUF218 domain
HFFHMGJP_00778 4.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HFFHMGJP_00779 2.4e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFFHMGJP_00780 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HFFHMGJP_00781 0.0 uvrA3 L excinuclease ABC, A subunit
HFFHMGJP_00782 5.1e-122 S SNARE associated Golgi protein
HFFHMGJP_00783 1.3e-229 N Uncharacterized conserved protein (DUF2075)
HFFHMGJP_00784 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HFFHMGJP_00786 5.1e-254 yifK E Amino acid permease
HFFHMGJP_00787 3.6e-157 endA V DNA/RNA non-specific endonuclease
HFFHMGJP_00788 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFFHMGJP_00789 3.5e-42 ybaN S Protein of unknown function (DUF454)
HFFHMGJP_00790 4.1e-72 S Protein of unknown function (DUF3290)
HFFHMGJP_00791 1.8e-113 yviA S Protein of unknown function (DUF421)
HFFHMGJP_00792 5.2e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HFFHMGJP_00793 7e-19
HFFHMGJP_00794 4e-89 ntd 2.4.2.6 F Nucleoside
HFFHMGJP_00795 1.6e-154 3.1.3.102, 3.1.3.104 S hydrolase
HFFHMGJP_00796 3.7e-47 yrvD S Pfam:DUF1049
HFFHMGJP_00798 2.1e-141 L Belongs to the 'phage' integrase family
HFFHMGJP_00799 8.6e-95 K SIR2-like domain
HFFHMGJP_00800 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_00801 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00802 1.4e-139 T GHKL domain
HFFHMGJP_00803 5.3e-85 S Double zinc ribbon
HFFHMGJP_00804 2.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HFFHMGJP_00805 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
HFFHMGJP_00806 2.5e-138 IQ KR domain
HFFHMGJP_00807 3.3e-133 S membrane transporter protein
HFFHMGJP_00808 1.9e-95 S ABC-type cobalt transport system, permease component
HFFHMGJP_00809 6.4e-249 cbiO1 S ABC transporter, ATP-binding protein
HFFHMGJP_00810 6.3e-114 P Cobalt transport protein
HFFHMGJP_00811 1.6e-52 yvlA
HFFHMGJP_00812 0.0 yjcE P Sodium proton antiporter
HFFHMGJP_00813 2.2e-52 ypaA S Protein of unknown function (DUF1304)
HFFHMGJP_00814 3.8e-187 D Alpha beta
HFFHMGJP_00815 1e-72 K Transcriptional regulator
HFFHMGJP_00816 9.1e-161
HFFHMGJP_00817 2.8e-174 1.6.5.5 C Zinc-binding dehydrogenase
HFFHMGJP_00818 5.9e-258 G PTS system Galactitol-specific IIC component
HFFHMGJP_00819 3.1e-212 EGP Major facilitator Superfamily
HFFHMGJP_00820 4.4e-134 V ABC transporter
HFFHMGJP_00821 3.7e-107
HFFHMGJP_00822 1.8e-14
HFFHMGJP_00823 7.1e-63
HFFHMGJP_00824 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00825 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HFFHMGJP_00826 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HFFHMGJP_00827 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HFFHMGJP_00828 1.9e-239 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HFFHMGJP_00829 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HFFHMGJP_00830 3.5e-236 pbuG S permease
HFFHMGJP_00831 2.3e-270 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HFFHMGJP_00832 2e-184 gadC E amino acid
HFFHMGJP_00833 1.9e-96 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFFHMGJP_00834 8.3e-262 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HFFHMGJP_00835 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HFFHMGJP_00836 2.7e-140 S Belongs to the UPF0246 family
HFFHMGJP_00837 2.5e-138 S Membrane
HFFHMGJP_00838 1.8e-74 4.4.1.5 E Glyoxalase
HFFHMGJP_00839 1.5e-21
HFFHMGJP_00840 7.9e-85 yueI S Protein of unknown function (DUF1694)
HFFHMGJP_00841 1.3e-243 rarA L recombination factor protein RarA
HFFHMGJP_00842 5.7e-46
HFFHMGJP_00843 4.3e-83 usp6 T universal stress protein
HFFHMGJP_00844 1.7e-207 araR K Transcriptional regulator
HFFHMGJP_00845 4.6e-157 ytbE 1.1.1.346 S Aldo keto reductase
HFFHMGJP_00846 1.3e-99 maa 2.3.1.79 S Maltose O-acetyltransferase
HFFHMGJP_00847 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HFFHMGJP_00848 4.9e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HFFHMGJP_00849 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HFFHMGJP_00850 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HFFHMGJP_00851 2.5e-145 K transcriptional regulator, ArsR family
HFFHMGJP_00852 4e-173 abf G Belongs to the glycosyl hydrolase 43 family
HFFHMGJP_00853 3.5e-217 lacY G Oligosaccharide H symporter
HFFHMGJP_00854 7.9e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HFFHMGJP_00855 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HFFHMGJP_00856 3e-47 gcvH E glycine cleavage
HFFHMGJP_00857 1.1e-220 rodA D Belongs to the SEDS family
HFFHMGJP_00858 1e-31 S Protein of unknown function (DUF2969)
HFFHMGJP_00859 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HFFHMGJP_00860 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFFHMGJP_00861 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HFFHMGJP_00862 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HFFHMGJP_00863 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HFFHMGJP_00864 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HFFHMGJP_00865 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HFFHMGJP_00866 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFFHMGJP_00867 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HFFHMGJP_00868 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HFFHMGJP_00869 7.6e-121 atpB C it plays a direct role in the translocation of protons across the membrane
HFFHMGJP_00870 5.9e-233 pyrP F Permease
HFFHMGJP_00871 2.2e-129 yibF S overlaps another CDS with the same product name
HFFHMGJP_00872 4.4e-192 yibE S overlaps another CDS with the same product name
HFFHMGJP_00873 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFFHMGJP_00874 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HFFHMGJP_00875 2.5e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HFFHMGJP_00876 1.6e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HFFHMGJP_00877 1e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HFFHMGJP_00878 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HFFHMGJP_00879 6e-108 tdk 2.7.1.21 F thymidine kinase
HFFHMGJP_00880 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HFFHMGJP_00881 4.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HFFHMGJP_00882 1.2e-221 arcD U Amino acid permease
HFFHMGJP_00883 9.8e-261 E Arginine ornithine antiporter
HFFHMGJP_00884 2.7e-79 argR K Regulates arginine biosynthesis genes
HFFHMGJP_00885 5.9e-238 arcA 3.5.3.6 E Arginine
HFFHMGJP_00886 1.3e-195 ampC V Beta-lactamase
HFFHMGJP_00887 7.7e-34
HFFHMGJP_00888 0.0 M domain protein
HFFHMGJP_00889 7.6e-91
HFFHMGJP_00890 3.9e-132 L Belongs to the 'phage' integrase family
HFFHMGJP_00891 1.8e-27 K Cro/C1-type HTH DNA-binding domain
HFFHMGJP_00892 4.6e-17 S Helix-turn-helix domain
HFFHMGJP_00893 6.9e-46 S Phage regulatory protein Rha (Phage_pRha)
HFFHMGJP_00896 3.9e-08
HFFHMGJP_00903 1.4e-66
HFFHMGJP_00908 3.3e-254 yjcE P Sodium proton antiporter
HFFHMGJP_00909 3.6e-57
HFFHMGJP_00911 1.1e-88
HFFHMGJP_00912 0.0 copA 3.6.3.54 P P-type ATPase
HFFHMGJP_00913 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HFFHMGJP_00914 8.7e-52 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HFFHMGJP_00915 3.8e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HFFHMGJP_00916 5.1e-162 EG EamA-like transporter family
HFFHMGJP_00917 5.6e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HFFHMGJP_00918 5.8e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HFFHMGJP_00919 9.5e-155 KT YcbB domain
HFFHMGJP_00922 2.7e-26
HFFHMGJP_00923 3.4e-263 pgi 5.3.1.9 G Belongs to the GPI family
HFFHMGJP_00924 6.8e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
HFFHMGJP_00925 2e-155 glcU U sugar transport
HFFHMGJP_00926 2.4e-273 yclK 2.7.13.3 T Histidine kinase
HFFHMGJP_00927 3e-133 K response regulator
HFFHMGJP_00929 2.8e-79 lytE M Lysin motif
HFFHMGJP_00930 1.4e-147 XK27_02985 S Cof-like hydrolase
HFFHMGJP_00931 2.3e-81 K Transcriptional regulator
HFFHMGJP_00932 0.0 oatA I Acyltransferase
HFFHMGJP_00933 8.7e-53
HFFHMGJP_00934 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HFFHMGJP_00935 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFFHMGJP_00936 2e-126 ybbR S YbbR-like protein
HFFHMGJP_00937 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HFFHMGJP_00938 3.1e-248 fucP G Major Facilitator Superfamily
HFFHMGJP_00939 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HFFHMGJP_00940 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFFHMGJP_00941 2.1e-168 murB 1.3.1.98 M Cell wall formation
HFFHMGJP_00942 6e-102 dnaQ 2.7.7.7 L DNA polymerase III
HFFHMGJP_00943 4.4e-76 S PAS domain
HFFHMGJP_00944 1.1e-86 K Acetyltransferase (GNAT) domain
HFFHMGJP_00945 2.2e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HFFHMGJP_00946 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HFFHMGJP_00947 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HFFHMGJP_00948 1.8e-104 yxjI
HFFHMGJP_00949 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HFFHMGJP_00950 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HFFHMGJP_00951 8.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
HFFHMGJP_00952 1.8e-34 secG U Preprotein translocase
HFFHMGJP_00953 5.6e-294 clcA P chloride
HFFHMGJP_00954 7.1e-248 yifK E Amino acid permease
HFFHMGJP_00955 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HFFHMGJP_00956 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFFHMGJP_00957 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HFFHMGJP_00958 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HFFHMGJP_00960 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HFFHMGJP_00961 2.6e-242 glpT G Major Facilitator Superfamily
HFFHMGJP_00962 8.8e-15
HFFHMGJP_00964 4e-170 whiA K May be required for sporulation
HFFHMGJP_00965 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HFFHMGJP_00966 1.1e-161 rapZ S Displays ATPase and GTPase activities
HFFHMGJP_00967 1.6e-244 steT E amino acid
HFFHMGJP_00968 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HFFHMGJP_00969 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HFFHMGJP_00970 1.5e-13
HFFHMGJP_00971 2.3e-116 yfbR S HD containing hydrolase-like enzyme
HFFHMGJP_00972 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HFFHMGJP_00973 3e-87 ykhA 3.1.2.20 I Thioesterase superfamily
HFFHMGJP_00974 2e-158 aatB ET PFAM extracellular solute-binding protein, family 3
HFFHMGJP_00975 9.3e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HFFHMGJP_00976 4.6e-174 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HFFHMGJP_00977 4.6e-163 lutA C Cysteine-rich domain
HFFHMGJP_00978 2.4e-286 lutB C 4Fe-4S dicluster domain
HFFHMGJP_00979 3.9e-136 yrjD S LUD domain
HFFHMGJP_00980 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_00981 1.9e-113 mloB K Putative ATP-dependent DNA helicase recG C-terminal
HFFHMGJP_00984 2e-159 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HFFHMGJP_00985 1.8e-43 hxlR K Transcriptional regulator, HxlR family
HFFHMGJP_00986 4.3e-158 spoU 2.1.1.185 J Methyltransferase
HFFHMGJP_00987 6e-100 ywlG S Belongs to the UPF0340 family
HFFHMGJP_00988 1.5e-195 EGP Major facilitator Superfamily
HFFHMGJP_00989 9.8e-112 M Lysin motif
HFFHMGJP_00990 1.2e-79
HFFHMGJP_00991 1.5e-157 L hmm pf00665
HFFHMGJP_00992 1.7e-128 L Helix-turn-helix domain
HFFHMGJP_00993 1.8e-167 P CorA-like Mg2+ transporter protein
HFFHMGJP_00994 6.6e-98 wecD3 K PFAM GCN5-related N-acetyltransferase
HFFHMGJP_00995 6.6e-202 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HFFHMGJP_00996 4.3e-13
HFFHMGJP_00997 5.9e-79 S Domain of unknown function (DUF4767)
HFFHMGJP_00998 1.3e-196 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HFFHMGJP_00999 2.7e-114 S Membrane
HFFHMGJP_01000 1.4e-124 O Zinc-dependent metalloprotease
HFFHMGJP_01001 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HFFHMGJP_01002 7.5e-155 metQ_4 P Belongs to the nlpA lipoprotein family
HFFHMGJP_01003 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_01004 1.8e-232 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HFFHMGJP_01005 5.1e-173 scrR K Transcriptional regulator, LacI family
HFFHMGJP_01006 1e-24
HFFHMGJP_01007 5.5e-107
HFFHMGJP_01008 2.4e-215 yttB EGP Major facilitator Superfamily
HFFHMGJP_01009 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HFFHMGJP_01010 1.3e-87
HFFHMGJP_01011 4.2e-110 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HFFHMGJP_01012 7.2e-79 L hmm pf00665
HFFHMGJP_01013 2.4e-55 L Helix-turn-helix domain
HFFHMGJP_01014 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_01015 7.8e-275 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HFFHMGJP_01016 2.1e-39 gcvR T Belongs to the UPF0237 family
HFFHMGJP_01017 8.7e-243 XK27_08635 S UPF0210 protein
HFFHMGJP_01018 2.4e-95 K Acetyltransferase (GNAT) domain
HFFHMGJP_01019 2e-160 S Alpha beta hydrolase
HFFHMGJP_01020 9.9e-160 gspA M family 8
HFFHMGJP_01021 8.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFFHMGJP_01022 1.8e-92
HFFHMGJP_01023 6.4e-162 degV S EDD domain protein, DegV family
HFFHMGJP_01024 0.0 FbpA K Fibronectin-binding protein
HFFHMGJP_01025 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HFFHMGJP_01026 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
HFFHMGJP_01027 9e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFFHMGJP_01028 2.2e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HFFHMGJP_01029 1.5e-65 esbA S Family of unknown function (DUF5322)
HFFHMGJP_01030 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
HFFHMGJP_01031 1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HFFHMGJP_01032 9.4e-83 F Belongs to the NrdI family
HFFHMGJP_01033 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HFFHMGJP_01034 3.2e-101 ypsA S Belongs to the UPF0398 family
HFFHMGJP_01035 7.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HFFHMGJP_01036 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HFFHMGJP_01038 0.0 M LPXTG-motif cell wall anchor domain protein
HFFHMGJP_01039 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HFFHMGJP_01040 1.2e-105 ahpC 1.11.1.15 O Peroxiredoxin
HFFHMGJP_01041 3e-143 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HFFHMGJP_01042 2.9e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HFFHMGJP_01044 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFFHMGJP_01045 2.4e-166 T Calcineurin-like phosphoesterase superfamily domain
HFFHMGJP_01046 1.1e-223 mdtG EGP Major facilitator Superfamily
HFFHMGJP_01047 8.9e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HFFHMGJP_01048 6.8e-159 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HFFHMGJP_01049 2.7e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFFHMGJP_01050 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HFFHMGJP_01051 0.0 lacS G Transporter
HFFHMGJP_01052 2.3e-143 L PFAM Integrase catalytic region
HFFHMGJP_01053 3.3e-41 L Helix-turn-helix domain
HFFHMGJP_01055 0.0 UW LPXTG-motif cell wall anchor domain protein
HFFHMGJP_01056 0.0 UW LPXTG-motif cell wall anchor domain protein
HFFHMGJP_01057 0.0 UW LPXTG-motif cell wall anchor domain protein
HFFHMGJP_01058 4.6e-181 S Phosphotransferase system, EIIC
HFFHMGJP_01059 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HFFHMGJP_01060 4.3e-181
HFFHMGJP_01061 1.1e-64 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFFHMGJP_01062 1.6e-205 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HFFHMGJP_01063 5.2e-159 K LysR substrate binding domain
HFFHMGJP_01064 1.1e-107 manA 5.3.1.8 G mannose-6-phosphate isomerase
HFFHMGJP_01065 4.4e-97 2.3.1.128 K acetyltransferase
HFFHMGJP_01066 3.8e-182
HFFHMGJP_01067 4.4e-17 K Transcriptional regulator, HxlR family
HFFHMGJP_01068 4e-223 P ammonium transporter
HFFHMGJP_01069 5.6e-97 ureI S AmiS/UreI family transporter
HFFHMGJP_01070 3.7e-48 ureA 3.5.1.5 E Urease, gamma subunit
HFFHMGJP_01071 2.1e-69 ureB 3.5.1.5 E Urease beta subunit
HFFHMGJP_01072 0.0 ureC 3.5.1.5 E Amidohydrolase family
HFFHMGJP_01073 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HFFHMGJP_01074 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HFFHMGJP_01075 3.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HFFHMGJP_01076 3.2e-166 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
HFFHMGJP_01077 8.2e-185 nikMN P PDGLE domain
HFFHMGJP_01078 6.5e-135 P Cobalt transport protein
HFFHMGJP_01079 8.6e-136 cbiO P ABC transporter
HFFHMGJP_01080 3.5e-134 K Transcriptional regulatory protein, C-terminal domain protein
HFFHMGJP_01081 1.5e-158 pstS P Phosphate
HFFHMGJP_01082 1.9e-153 pstC P probably responsible for the translocation of the substrate across the membrane
HFFHMGJP_01083 6.5e-154 pstA P Phosphate transport system permease protein PstA
HFFHMGJP_01084 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HFFHMGJP_01085 3.9e-125 phoU P Plays a role in the regulation of phosphate uptake
HFFHMGJP_01086 1.5e-134
HFFHMGJP_01088 1.4e-242 ydaM M Glycosyl transferase
HFFHMGJP_01089 3.6e-221 G Glycosyl hydrolases family 8
HFFHMGJP_01090 3.6e-137 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HFFHMGJP_01091 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HFFHMGJP_01092 2e-239 ktrB P Potassium uptake protein
HFFHMGJP_01093 1.4e-116 ktrA P domain protein
HFFHMGJP_01094 2.7e-81 Q Methyltransferase
HFFHMGJP_01098 1.8e-11
HFFHMGJP_01101 1.2e-26 agrA K LytTr DNA-binding domain
HFFHMGJP_01103 3.3e-07 agrA K LytTr DNA-binding domain
HFFHMGJP_01104 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
HFFHMGJP_01105 3.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HFFHMGJP_01106 1.6e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFFHMGJP_01107 1.4e-95 S NADPH-dependent FMN reductase
HFFHMGJP_01108 2.1e-180 MA20_14895 S Conserved hypothetical protein 698
HFFHMGJP_01109 1.1e-135 I alpha/beta hydrolase fold
HFFHMGJP_01110 3.1e-169 lsa S ABC transporter
HFFHMGJP_01111 1.6e-179 yfeX P Peroxidase
HFFHMGJP_01112 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
HFFHMGJP_01113 6.6e-259 ytjP 3.5.1.18 E Dipeptidase
HFFHMGJP_01114 5.8e-214 uhpT EGP Major facilitator Superfamily
HFFHMGJP_01115 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HFFHMGJP_01116 3.5e-130 ponA V Beta-lactamase enzyme family
HFFHMGJP_01117 7.3e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HFFHMGJP_01118 3e-75
HFFHMGJP_01119 1.6e-292 fhaB M Rib/alpha-like repeat
HFFHMGJP_01120 4.1e-11 fhaB M Rib/alpha-like repeat
HFFHMGJP_01121 0.0 fhaB M Rib/alpha-like repeat
HFFHMGJP_01122 4.1e-11 fhaB M Rib/alpha-like repeat
HFFHMGJP_01124 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
HFFHMGJP_01125 2.7e-296 L Transposase IS66 family
HFFHMGJP_01126 1.2e-12 QT PucR C-terminal helix-turn-helix domain
HFFHMGJP_01127 1.9e-89 3.1.11.5 L A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HFFHMGJP_01129 8.3e-137 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HFFHMGJP_01130 3.3e-197 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HFFHMGJP_01132 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01133 2.7e-296 L Transposase IS66 family
HFFHMGJP_01134 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
HFFHMGJP_01137 2.8e-19
HFFHMGJP_01138 1.3e-263 dtpT U amino acid peptide transporter
HFFHMGJP_01139 2e-157 yjjH S Calcineurin-like phosphoesterase
HFFHMGJP_01142 2.4e-113
HFFHMGJP_01143 2.6e-250 EGP Major facilitator Superfamily
HFFHMGJP_01144 6.7e-298 aspT P Predicted Permease Membrane Region
HFFHMGJP_01145 3.4e-129 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HFFHMGJP_01146 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HFFHMGJP_01147 1.3e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFFHMGJP_01148 4.4e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HFFHMGJP_01149 0.0 yhgF K Tex-like protein N-terminal domain protein
HFFHMGJP_01150 1.9e-85 ydcK S Belongs to the SprT family
HFFHMGJP_01152 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HFFHMGJP_01153 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HFFHMGJP_01154 0.0 S Bacterial membrane protein, YfhO
HFFHMGJP_01155 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFFHMGJP_01156 1.3e-167 I alpha/beta hydrolase fold
HFFHMGJP_01157 7.7e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HFFHMGJP_01158 1.1e-119 tcyB E ABC transporter
HFFHMGJP_01159 4.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFFHMGJP_01160 4.3e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HFFHMGJP_01161 1.3e-267 pepC 3.4.22.40 E Peptidase C1-like family
HFFHMGJP_01162 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HFFHMGJP_01163 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
HFFHMGJP_01164 4.7e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HFFHMGJP_01165 1.6e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HFFHMGJP_01166 1.7e-207 yacL S domain protein
HFFHMGJP_01167 1.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFFHMGJP_01168 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HFFHMGJP_01169 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFFHMGJP_01170 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFFHMGJP_01171 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HFFHMGJP_01172 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HFFHMGJP_01173 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HFFHMGJP_01174 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HFFHMGJP_01175 7.8e-227 aadAT EK Aminotransferase, class I
HFFHMGJP_01177 2.6e-244 M Glycosyl transferase family group 2
HFFHMGJP_01178 1.7e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFFHMGJP_01179 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HFFHMGJP_01180 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HFFHMGJP_01181 7.7e-48
HFFHMGJP_01183 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HFFHMGJP_01184 2.4e-56 K transcriptional regulator PadR family
HFFHMGJP_01185 5.1e-73 XK27_06920 S Protein of unknown function (DUF1700)
HFFHMGJP_01186 4.6e-132 S Putative adhesin
HFFHMGJP_01187 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HFFHMGJP_01188 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01189 3.3e-41 L Helix-turn-helix domain
HFFHMGJP_01190 2.3e-143 L PFAM Integrase catalytic region
HFFHMGJP_01191 1.6e-112
HFFHMGJP_01192 5.4e-153 V ABC transporter, ATP-binding protein
HFFHMGJP_01193 9.3e-65 gntR1 K Transcriptional regulator, GntR family
HFFHMGJP_01194 3.5e-55 ponA V the current gene model (or a revised gene model) may contain a frame shift
HFFHMGJP_01195 1.7e-56 M Peptidase_C39 like family
HFFHMGJP_01196 1.8e-52 M NlpC P60 family protein
HFFHMGJP_01197 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
HFFHMGJP_01198 2.6e-39 S dextransucrase activity
HFFHMGJP_01199 3.7e-309 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFFHMGJP_01200 3.4e-216 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFFHMGJP_01201 3.3e-161 S Psort location CytoplasmicMembrane, score
HFFHMGJP_01202 5.9e-160 yueF S AI-2E family transporter
HFFHMGJP_01203 3.5e-53 S dextransucrase activity
HFFHMGJP_01205 2.2e-47 L PFAM transposase IS200-family protein
HFFHMGJP_01206 3.1e-149 M Glycosyltransferase like family 2
HFFHMGJP_01207 1.1e-26
HFFHMGJP_01208 4.3e-108 M repeat protein
HFFHMGJP_01209 1.5e-59 M KxYKxGKxW signal domain protein
HFFHMGJP_01210 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01211 1.5e-121 K response regulator
HFFHMGJP_01212 4.1e-278 arlS 2.7.13.3 T Histidine kinase
HFFHMGJP_01213 2.3e-268 yjeM E Amino Acid
HFFHMGJP_01214 1.3e-230 V MatE
HFFHMGJP_01215 7.4e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HFFHMGJP_01216 7.2e-167 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HFFHMGJP_01217 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HFFHMGJP_01218 4.8e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFFHMGJP_01219 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HFFHMGJP_01220 6.7e-59 yodB K Transcriptional regulator, HxlR family
HFFHMGJP_01221 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HFFHMGJP_01222 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HFFHMGJP_01223 1e-116 rlpA M PFAM NLP P60 protein
HFFHMGJP_01224 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HFFHMGJP_01225 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFFHMGJP_01226 2.6e-70 yneR S Belongs to the HesB IscA family
HFFHMGJP_01227 0.0 S membrane
HFFHMGJP_01228 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HFFHMGJP_01229 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HFFHMGJP_01230 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFFHMGJP_01231 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
HFFHMGJP_01232 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HFFHMGJP_01233 1.5e-183 glk 2.7.1.2 G Glucokinase
HFFHMGJP_01234 3.4e-67 yqhL P Rhodanese-like protein
HFFHMGJP_01235 5.9e-22 S Protein of unknown function (DUF3042)
HFFHMGJP_01236 1.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HFFHMGJP_01237 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01238 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01239 1.1e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HFFHMGJP_01240 1.5e-103 T Ion transport 2 domain protein
HFFHMGJP_01241 0.0 S Bacterial membrane protein YfhO
HFFHMGJP_01242 2.5e-201 G Transporter, major facilitator family protein
HFFHMGJP_01243 2.4e-109 yvrI K sigma factor activity
HFFHMGJP_01244 4.5e-64 ydiI Q Thioesterase superfamily
HFFHMGJP_01245 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HFFHMGJP_01246 7.2e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HFFHMGJP_01247 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HFFHMGJP_01248 1.2e-31 feoA P FeoA domain
HFFHMGJP_01249 6.5e-145 sufC O FeS assembly ATPase SufC
HFFHMGJP_01250 2.8e-238 sufD O FeS assembly protein SufD
HFFHMGJP_01251 8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFFHMGJP_01252 1.2e-79 nifU C SUF system FeS assembly protein, NifU family
HFFHMGJP_01253 2.3e-270 sufB O assembly protein SufB
HFFHMGJP_01254 2.8e-57 yitW S Iron-sulfur cluster assembly protein
HFFHMGJP_01255 4.2e-161 hipB K Helix-turn-helix
HFFHMGJP_01256 3.4e-115 nreC K PFAM regulatory protein LuxR
HFFHMGJP_01257 9.2e-39 S Cytochrome B5
HFFHMGJP_01258 6.4e-156 yitU 3.1.3.104 S hydrolase
HFFHMGJP_01259 1.5e-258 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HFFHMGJP_01260 4e-148 f42a O Band 7 protein
HFFHMGJP_01261 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HFFHMGJP_01262 1.1e-130 lytT K response regulator receiver
HFFHMGJP_01263 1.9e-66 lrgA S LrgA family
HFFHMGJP_01264 2.6e-124 lrgB M LrgB-like family
HFFHMGJP_01265 1.1e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFFHMGJP_01266 4.9e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HFFHMGJP_01267 4.8e-185 galR K Periplasmic binding protein-like domain
HFFHMGJP_01268 0.0 rafA 3.2.1.22 G alpha-galactosidase
HFFHMGJP_01269 3.8e-87 S Protein of unknown function (DUF1440)
HFFHMGJP_01270 3.8e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HFFHMGJP_01271 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HFFHMGJP_01272 1.2e-161 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HFFHMGJP_01273 2e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HFFHMGJP_01274 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HFFHMGJP_01275 7.6e-86 ypmB S Protein conserved in bacteria
HFFHMGJP_01276 7.3e-124 dnaD L DnaD domain protein
HFFHMGJP_01277 1.4e-162 EG EamA-like transporter family
HFFHMGJP_01278 2.3e-143 L PFAM Integrase catalytic region
HFFHMGJP_01279 3.3e-41 L Helix-turn-helix domain
HFFHMGJP_01280 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01281 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFFHMGJP_01282 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFFHMGJP_01283 3.4e-35 nrdH O Glutaredoxin
HFFHMGJP_01284 2.3e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HFFHMGJP_01285 6.4e-281 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFFHMGJP_01286 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HFFHMGJP_01287 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFFHMGJP_01288 9.7e-39 S Protein of unknown function (DUF2508)
HFFHMGJP_01289 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HFFHMGJP_01290 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HFFHMGJP_01291 8.2e-185 holB 2.7.7.7 L DNA polymerase III
HFFHMGJP_01292 5.9e-58 yabA L Involved in initiation control of chromosome replication
HFFHMGJP_01293 1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HFFHMGJP_01294 4.8e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
HFFHMGJP_01295 6.3e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFFHMGJP_01296 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HFFHMGJP_01297 3.3e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFFHMGJP_01298 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HFFHMGJP_01299 7.3e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HFFHMGJP_01300 4.3e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HFFHMGJP_01301 4.2e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HFFHMGJP_01302 3.6e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFFHMGJP_01303 2.8e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HFFHMGJP_01304 3.8e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HFFHMGJP_01305 5.1e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HFFHMGJP_01306 2.9e-226 mtnE 2.6.1.83 E Aminotransferase
HFFHMGJP_01307 3.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HFFHMGJP_01308 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01309 2.4e-09 5.1.1.1, 5.1.1.18 I Acyltransferase family
HFFHMGJP_01310 1.7e-135 S polysaccharide biosynthetic process
HFFHMGJP_01311 4.5e-49 MA20_43635 M Capsular polysaccharide synthesis protein
HFFHMGJP_01313 7.3e-21 tagF 2.7.8.12 M Glycosyltransferase like family 2
HFFHMGJP_01314 2e-34 M transferase activity, transferring glycosyl groups
HFFHMGJP_01315 3.9e-54 M transferase activity, transferring glycosyl groups
HFFHMGJP_01316 7.6e-91 tuaA M Bacterial sugar transferase
HFFHMGJP_01317 4e-138 cps2D 5.1.3.2 M RmlD substrate binding domain
HFFHMGJP_01318 1.2e-119 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HFFHMGJP_01319 1.1e-140 epsB M biosynthesis protein
HFFHMGJP_01320 1.9e-165 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HFFHMGJP_01321 4.2e-68 K Transcriptional regulator, HxlR family
HFFHMGJP_01322 2.5e-127
HFFHMGJP_01323 1.3e-102 K DNA-templated transcription, initiation
HFFHMGJP_01324 3.3e-36
HFFHMGJP_01325 4.5e-83
HFFHMGJP_01326 1.4e-289 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFFHMGJP_01327 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HFFHMGJP_01328 1e-310 yjbQ P TrkA C-terminal domain protein
HFFHMGJP_01329 1.3e-270 pipD E Dipeptidase
HFFHMGJP_01331 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01332 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
HFFHMGJP_01333 4e-146 L Belongs to the 'phage' integrase family
HFFHMGJP_01334 1.1e-42
HFFHMGJP_01335 9e-17
HFFHMGJP_01336 4.1e-40 E Zn peptidase
HFFHMGJP_01337 2.6e-36 K Helix-turn-helix XRE-family like proteins
HFFHMGJP_01339 3e-67 S DNA binding
HFFHMGJP_01347 1.4e-11 S Bacteriophage Mu Gam like protein
HFFHMGJP_01348 6.9e-43 S ERF superfamily
HFFHMGJP_01349 5.3e-92 S Putative HNHc nuclease
HFFHMGJP_01350 2.3e-44 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HFFHMGJP_01351 4.7e-58 S calcium ion binding
HFFHMGJP_01352 1.3e-52 dnaC 3.4.21.53 L IstB-like ATP binding protein
HFFHMGJP_01360 7.3e-56 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HFFHMGJP_01363 2.4e-24
HFFHMGJP_01365 6.7e-22 S Mazg nucleotide pyrophosphohydrolase
HFFHMGJP_01367 2.4e-29 rusA L Endodeoxyribonuclease RusA
HFFHMGJP_01370 1.5e-11
HFFHMGJP_01372 1.2e-19
HFFHMGJP_01373 6.6e-76 xtmA L Terminase small subunit
HFFHMGJP_01374 9.7e-191 S Terminase-like family
HFFHMGJP_01375 2.8e-183 S Phage portal protein, SPP1 Gp6-like
HFFHMGJP_01376 1.3e-92
HFFHMGJP_01378 3.6e-29 S Domain of unknown function (DUF4355)
HFFHMGJP_01379 1.9e-98
HFFHMGJP_01380 2e-18
HFFHMGJP_01381 2.5e-29
HFFHMGJP_01382 6.2e-49 Z012_02125
HFFHMGJP_01384 2.8e-23
HFFHMGJP_01385 5.9e-104 Z012_02110 S Protein of unknown function (DUF3383)
HFFHMGJP_01386 4.5e-38
HFFHMGJP_01387 6.4e-14
HFFHMGJP_01389 6.2e-29
HFFHMGJP_01390 7e-53 3.5.1.28 M LysM domain
HFFHMGJP_01391 3e-35
HFFHMGJP_01392 3.2e-89
HFFHMGJP_01393 1.9e-27
HFFHMGJP_01394 1.7e-09 S Protein of unknown function (DUF2634)
HFFHMGJP_01395 9.4e-119 Z012_12235 S Baseplate J-like protein
HFFHMGJP_01396 9.7e-28
HFFHMGJP_01397 5.1e-99 G cellulose 1,4-beta-cellobiosidase activity
HFFHMGJP_01400 1e-39
HFFHMGJP_01401 1.9e-27 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HFFHMGJP_01402 2.9e-96 S N-acetylmuramoyl-L-alanine amidase activity
HFFHMGJP_01403 1.2e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFFHMGJP_01404 3.2e-121 L hmm pf00665
HFFHMGJP_01405 1e-125 L Helix-turn-helix domain
HFFHMGJP_01406 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01407 4.1e-14 S SIR2-like domain
HFFHMGJP_01408 2e-18
HFFHMGJP_01409 2.3e-12
HFFHMGJP_01410 1.8e-79 3.4.21.88 K Peptidase S24-like
HFFHMGJP_01411 2.8e-10 K Helix-turn-helix XRE-family like proteins
HFFHMGJP_01412 7.2e-20
HFFHMGJP_01414 2.5e-13 K Cro/C1-type HTH DNA-binding domain
HFFHMGJP_01415 4.3e-20
HFFHMGJP_01418 7e-111 L DnaD domain protein
HFFHMGJP_01419 1.4e-86 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HFFHMGJP_01420 8.3e-139 L Belongs to the 'phage' integrase family
HFFHMGJP_01422 2.2e-09
HFFHMGJP_01423 2.9e-41 S HNH endonuclease
HFFHMGJP_01425 2.2e-67
HFFHMGJP_01426 2.1e-129
HFFHMGJP_01428 7.9e-18
HFFHMGJP_01432 4.2e-83 arpU S Phage transcriptional regulator, ArpU family
HFFHMGJP_01433 1.9e-14
HFFHMGJP_01434 1.2e-08
HFFHMGJP_01435 7.1e-152 L HNH nucleases
HFFHMGJP_01436 3.4e-77 terS L Phage terminase, small subunit
HFFHMGJP_01437 0.0 terL S overlaps another CDS with the same product name
HFFHMGJP_01439 7.1e-239 S Phage portal protein
HFFHMGJP_01440 2.4e-113 pi136 S Caudovirus prohead serine protease
HFFHMGJP_01441 7e-209 S Phage capsid family
HFFHMGJP_01442 9.7e-68 S Phage gp6-like head-tail connector protein
HFFHMGJP_01443 6.6e-40 S Phage head-tail joining protein
HFFHMGJP_01444 8.5e-63 S Bacteriophage HK97-gp10, putative tail-component
HFFHMGJP_01445 7.5e-76
HFFHMGJP_01446 8e-114
HFFHMGJP_01447 7.9e-23
HFFHMGJP_01448 1.5e-19
HFFHMGJP_01449 0.0 M Phage tail tape measure protein TP901
HFFHMGJP_01450 3.2e-158 S Phage tail protein
HFFHMGJP_01451 7.5e-143
HFFHMGJP_01452 1.8e-259 3.4.24.40 M Peptidase family M23
HFFHMGJP_01455 2.7e-49 cotH M CotH kinase protein
HFFHMGJP_01459 5.8e-36 S Bacteriophage holin family
HFFHMGJP_01460 1.5e-55 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HFFHMGJP_01461 8e-202 3.5.1.104 M hydrolase, family 25
HFFHMGJP_01465 2.7e-160 I alpha/beta hydrolase fold
HFFHMGJP_01466 9.7e-115 frnE Q DSBA-like thioredoxin domain
HFFHMGJP_01467 2.3e-54
HFFHMGJP_01468 8.6e-196 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HFFHMGJP_01471 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01472 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HFFHMGJP_01473 2.9e-99 yceD S Uncharacterized ACR, COG1399
HFFHMGJP_01474 1.4e-212 ylbM S Belongs to the UPF0348 family
HFFHMGJP_01475 1.7e-139 yqeM Q Methyltransferase
HFFHMGJP_01476 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HFFHMGJP_01477 2.5e-112 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HFFHMGJP_01478 1.1e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HFFHMGJP_01479 1.9e-47 yhbY J RNA-binding protein
HFFHMGJP_01480 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
HFFHMGJP_01481 6.3e-96 yqeG S HAD phosphatase, family IIIA
HFFHMGJP_01482 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HFFHMGJP_01483 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HFFHMGJP_01484 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HFFHMGJP_01485 9e-170 dnaI L Primosomal protein DnaI
HFFHMGJP_01486 1.6e-204 dnaB L replication initiation and membrane attachment
HFFHMGJP_01487 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFFHMGJP_01488 1.5e-101 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFFHMGJP_01489 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HFFHMGJP_01490 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFFHMGJP_01491 8.3e-117 yoaK S Protein of unknown function (DUF1275)
HFFHMGJP_01492 1e-125 L Helix-turn-helix domain
HFFHMGJP_01493 3.2e-121 L hmm pf00665
HFFHMGJP_01494 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01496 1.2e-73 K helix_turn_helix multiple antibiotic resistance protein
HFFHMGJP_01497 4.8e-311 lmrA 3.6.3.44 V ABC transporter
HFFHMGJP_01499 3.1e-130 K response regulator
HFFHMGJP_01500 0.0 vicK 2.7.13.3 T Histidine kinase
HFFHMGJP_01501 1e-248 yycH S YycH protein
HFFHMGJP_01502 5.4e-150 yycI S YycH protein
HFFHMGJP_01503 4.5e-154 vicX 3.1.26.11 S domain protein
HFFHMGJP_01504 7.1e-218 htrA 3.4.21.107 O serine protease
HFFHMGJP_01505 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HFFHMGJP_01506 2.1e-177 ABC-SBP S ABC transporter
HFFHMGJP_01507 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HFFHMGJP_01509 2.4e-95 S reductase
HFFHMGJP_01510 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HFFHMGJP_01511 7.5e-155 glcU U sugar transport
HFFHMGJP_01512 2.7e-148 E Glyoxalase-like domain
HFFHMGJP_01513 6e-146 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HFFHMGJP_01514 8.9e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HFFHMGJP_01515 2e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFFHMGJP_01516 6.3e-128 V ABC transporter
HFFHMGJP_01517 6e-214 bacI V MacB-like periplasmic core domain
HFFHMGJP_01518 6.8e-31
HFFHMGJP_01519 1.4e-264 S Putative peptidoglycan binding domain
HFFHMGJP_01523 1.1e-144 2.7.13.3 T GHKL domain
HFFHMGJP_01524 3.4e-135 K LytTr DNA-binding domain
HFFHMGJP_01525 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01526 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01527 1e-78 V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HFFHMGJP_01528 1e-128 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HFFHMGJP_01530 5e-75 osmC O OsmC-like protein
HFFHMGJP_01531 1e-176 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFHMGJP_01532 1.2e-219 patA 2.6.1.1 E Aminotransferase
HFFHMGJP_01533 2.7e-32
HFFHMGJP_01534 0.0 clpL O associated with various cellular activities
HFFHMGJP_01536 6.7e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
HFFHMGJP_01537 2e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFFHMGJP_01538 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HFFHMGJP_01539 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HFFHMGJP_01540 3.3e-172 malR K Transcriptional regulator, LacI family
HFFHMGJP_01541 7.7e-211 phbA 2.3.1.9 I Belongs to the thiolase family
HFFHMGJP_01542 1.1e-256 malT G Major Facilitator
HFFHMGJP_01543 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HFFHMGJP_01544 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HFFHMGJP_01545 1.4e-70
HFFHMGJP_01546 1.3e-87 2.7.6.5 T Region found in RelA / SpoT proteins
HFFHMGJP_01547 7.6e-115 K response regulator
HFFHMGJP_01548 1e-221 sptS 2.7.13.3 T Histidine kinase
HFFHMGJP_01549 4.9e-205 yfeO P Voltage gated chloride channel
HFFHMGJP_01550 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HFFHMGJP_01551 7.8e-137 puuD S peptidase C26
HFFHMGJP_01552 2.9e-167 yvgN C Aldo keto reductase
HFFHMGJP_01553 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HFFHMGJP_01554 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
HFFHMGJP_01555 5.3e-181 nox C NADH oxidase
HFFHMGJP_01556 1.1e-59 nox C NADH oxidase
HFFHMGJP_01557 4.2e-186 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HFFHMGJP_01558 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFFHMGJP_01559 2.2e-84
HFFHMGJP_01560 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HFFHMGJP_01562 9.9e-112 K Transcriptional regulator, TetR family
HFFHMGJP_01563 1e-69
HFFHMGJP_01564 5.3e-268 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HFFHMGJP_01565 1.9e-267 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HFFHMGJP_01566 1.1e-288 M domain protein
HFFHMGJP_01567 8.2e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFFHMGJP_01568 8.2e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFFHMGJP_01569 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HFFHMGJP_01570 2e-266 G Major Facilitator
HFFHMGJP_01571 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HFFHMGJP_01572 1e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HFFHMGJP_01573 4.7e-260 G Major Facilitator
HFFHMGJP_01574 1.6e-177 K Transcriptional regulator, LacI family
HFFHMGJP_01575 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFFHMGJP_01577 4.1e-101 nqr 1.5.1.36 S reductase
HFFHMGJP_01578 2.1e-198 XK27_09615 S reductase
HFFHMGJP_01579 2.2e-176 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HFFHMGJP_01580 8.2e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFFHMGJP_01581 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HFFHMGJP_01582 6.7e-54
HFFHMGJP_01583 4.9e-73 merR K MerR HTH family regulatory protein
HFFHMGJP_01584 2.7e-269 lmrB EGP Major facilitator Superfamily
HFFHMGJP_01585 2.3e-120 S Domain of unknown function (DUF4811)
HFFHMGJP_01586 4e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HFFHMGJP_01588 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HFFHMGJP_01589 5.7e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HFFHMGJP_01590 8.5e-187 I Alpha beta
HFFHMGJP_01591 8.2e-277 emrY EGP Major facilitator Superfamily
HFFHMGJP_01592 4.2e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
HFFHMGJP_01593 9.4e-253 yjjP S Putative threonine/serine exporter
HFFHMGJP_01594 1.4e-159 mleR K LysR family
HFFHMGJP_01595 7e-251 yflS P Sodium:sulfate symporter transmembrane region
HFFHMGJP_01596 1.3e-265 frdC 1.3.5.4 C FAD binding domain
HFFHMGJP_01597 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HFFHMGJP_01598 2.5e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HFFHMGJP_01599 7.5e-158 mleR K LysR family
HFFHMGJP_01600 1.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFFHMGJP_01601 1.3e-206 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HFFHMGJP_01602 1.3e-298 L PFAM plasmid pRiA4b ORF-3 family protein
HFFHMGJP_01603 1.3e-265 S Uncharacterized protein conserved in bacteria (DUF2252)
HFFHMGJP_01606 1.7e-21
HFFHMGJP_01607 5.4e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HFFHMGJP_01608 1e-125 L Helix-turn-helix domain
HFFHMGJP_01609 3.2e-121 L hmm pf00665
HFFHMGJP_01610 5e-167 map 3.4.11.18 E Methionine Aminopeptidase
HFFHMGJP_01611 6.1e-79 fld C Flavodoxin
HFFHMGJP_01612 1.3e-67 gtcA S Teichoic acid glycosylation protein
HFFHMGJP_01613 5.4e-56
HFFHMGJP_01614 4.4e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HFFHMGJP_01616 1.5e-231 yfmL L DEAD DEAH box helicase
HFFHMGJP_01617 4.5e-191 mocA S Oxidoreductase
HFFHMGJP_01618 9.1e-62 S Domain of unknown function (DUF4828)
HFFHMGJP_01619 1.7e-110 yvdD 3.2.2.10 S Belongs to the LOG family
HFFHMGJP_01620 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HFFHMGJP_01621 1.3e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HFFHMGJP_01622 6.3e-201 S Protein of unknown function (DUF3114)
HFFHMGJP_01623 5.8e-82 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HFFHMGJP_01624 1.6e-118 ybhL S Belongs to the BI1 family
HFFHMGJP_01625 1.4e-21
HFFHMGJP_01626 6.3e-93 K Acetyltransferase (GNAT) family
HFFHMGJP_01627 3.5e-76 K LytTr DNA-binding domain
HFFHMGJP_01628 7.3e-69 S Protein of unknown function (DUF3021)
HFFHMGJP_01629 1.5e-156 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HFFHMGJP_01630 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
HFFHMGJP_01631 2.4e-75 ogt 2.1.1.63 L Methyltransferase
HFFHMGJP_01632 4.4e-123 pnb C nitroreductase
HFFHMGJP_01633 1.1e-90
HFFHMGJP_01634 1.3e-91 S B3 4 domain
HFFHMGJP_01635 1.6e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HFFHMGJP_01636 1.7e-205 amtB P ammonium transporter
HFFHMGJP_01637 1.7e-90 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HFFHMGJP_01639 9.3e-61 XK27_04080 H Riboflavin biosynthesis protein RibD
HFFHMGJP_01640 5.1e-173 L Plasmid pRiA4b ORF-3-like protein
HFFHMGJP_01641 5.5e-87 S overlaps another CDS with the same product name
HFFHMGJP_01642 3.9e-56 S overlaps another CDS with the same product name
HFFHMGJP_01643 3.5e-27
HFFHMGJP_01644 1e-44 DJ ParE toxin of type II toxin-antitoxin system, parDE
HFFHMGJP_01645 1.3e-80 L Helix-turn-helix domain
HFFHMGJP_01646 1.1e-24 L PFAM Integrase catalytic region
HFFHMGJP_01647 5.4e-111 3.6.1.13, 3.6.1.55 F NUDIX domain
HFFHMGJP_01648 2e-229 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HFFHMGJP_01649 5.6e-79 pncA Q Isochorismatase family
HFFHMGJP_01650 1.8e-60 pldB 3.1.1.5 I Serine aminopeptidase, S33
HFFHMGJP_01652 2e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HFFHMGJP_01653 5.5e-95 dps P Belongs to the Dps family
HFFHMGJP_01654 1.3e-34 copZ C Heavy-metal-associated domain
HFFHMGJP_01655 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HFFHMGJP_01656 6.2e-102
HFFHMGJP_01657 1.9e-261 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HFFHMGJP_01658 3.5e-188 yegS 2.7.1.107 G Lipid kinase
HFFHMGJP_01659 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFFHMGJP_01660 5.9e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HFFHMGJP_01661 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFFHMGJP_01662 1.2e-202 camS S sex pheromone
HFFHMGJP_01663 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HFFHMGJP_01664 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HFFHMGJP_01665 3.6e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HFFHMGJP_01666 1.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HFFHMGJP_01667 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
HFFHMGJP_01668 9.4e-141 IQ reductase
HFFHMGJP_01669 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HFFHMGJP_01670 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HFFHMGJP_01671 7.2e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HFFHMGJP_01672 4.4e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFHMGJP_01673 5.9e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFHMGJP_01674 6.7e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HFFHMGJP_01675 1.1e-62 rplQ J Ribosomal protein L17
HFFHMGJP_01676 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFHMGJP_01677 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HFFHMGJP_01678 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HFFHMGJP_01679 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HFFHMGJP_01680 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HFFHMGJP_01681 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HFFHMGJP_01682 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HFFHMGJP_01683 8.9e-64 rplO J Binds to the 23S rRNA
HFFHMGJP_01684 2.9e-24 rpmD J Ribosomal protein L30
HFFHMGJP_01685 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HFFHMGJP_01686 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HFFHMGJP_01687 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HFFHMGJP_01688 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HFFHMGJP_01689 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HFFHMGJP_01690 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HFFHMGJP_01691 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HFFHMGJP_01692 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HFFHMGJP_01693 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HFFHMGJP_01694 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HFFHMGJP_01695 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HFFHMGJP_01696 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HFFHMGJP_01697 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HFFHMGJP_01698 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HFFHMGJP_01699 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HFFHMGJP_01700 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HFFHMGJP_01701 7.2e-107 rplD J Forms part of the polypeptide exit tunnel
HFFHMGJP_01702 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HFFHMGJP_01703 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HFFHMGJP_01704 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HFFHMGJP_01705 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HFFHMGJP_01706 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HFFHMGJP_01707 9.8e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HFFHMGJP_01708 6.1e-200 ykiI
HFFHMGJP_01709 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFHMGJP_01710 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HFFHMGJP_01711 1e-110 K Bacterial regulatory proteins, tetR family
HFFHMGJP_01712 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HFFHMGJP_01713 1.3e-76 ctsR K Belongs to the CtsR family
HFFHMGJP_01714 3.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HFFHMGJP_01715 1.7e-179 S Hydrolases of the alpha beta superfamily
HFFHMGJP_01721 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HFFHMGJP_01722 2.3e-276 lysP E amino acid
HFFHMGJP_01723 5.9e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
HFFHMGJP_01724 2.3e-119 lssY 3.6.1.27 I phosphatase
HFFHMGJP_01725 2.1e-82 S Threonine/Serine exporter, ThrE
HFFHMGJP_01726 1.1e-128 thrE S Putative threonine/serine exporter
HFFHMGJP_01727 1e-30 cspC K Cold shock protein
HFFHMGJP_01728 2.4e-124 sirR K iron dependent repressor
HFFHMGJP_01729 9.1e-167 czcD P cation diffusion facilitator family transporter
HFFHMGJP_01730 2.9e-117 S membrane
HFFHMGJP_01731 4.9e-109 S VIT family
HFFHMGJP_01732 2.7e-82 usp1 T Belongs to the universal stress protein A family
HFFHMGJP_01733 1.5e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFFHMGJP_01734 5.7e-152 glnH ET ABC transporter
HFFHMGJP_01735 3.2e-110 gluC P ABC transporter permease
HFFHMGJP_01736 1.4e-108 glnP P ABC transporter permease
HFFHMGJP_01737 9.2e-220 S CAAX protease self-immunity
HFFHMGJP_01738 8.2e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFFHMGJP_01739 1e-125 L Helix-turn-helix domain
HFFHMGJP_01740 3.2e-121 L hmm pf00665
HFFHMGJP_01741 3.4e-230 ndh 1.6.99.3 C NADH dehydrogenase
HFFHMGJP_01742 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HFFHMGJP_01743 6.7e-309 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HFFHMGJP_01744 4.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HFFHMGJP_01745 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
HFFHMGJP_01746 1.1e-250 L PFAM transposase, IS4 family protein
HFFHMGJP_01747 3.2e-121 L hmm pf00665
HFFHMGJP_01748 1e-125 L Helix-turn-helix domain
HFFHMGJP_01749 5.9e-219 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HFFHMGJP_01750 8.2e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFFHMGJP_01751 3.2e-121 L hmm pf00665
HFFHMGJP_01752 1e-125 L Helix-turn-helix domain
HFFHMGJP_01753 3.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HFFHMGJP_01754 6.8e-121 radC L DNA repair protein
HFFHMGJP_01755 1.7e-179 mreB D cell shape determining protein MreB
HFFHMGJP_01756 5.9e-152 mreC M Involved in formation and maintenance of cell shape
HFFHMGJP_01757 8.7e-93 mreD M rod shape-determining protein MreD
HFFHMGJP_01758 3.2e-102 glnP P ABC transporter permease
HFFHMGJP_01759 3.6e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFFHMGJP_01760 2.6e-160 aatB ET ABC transporter substrate-binding protein
HFFHMGJP_01761 1.7e-229 ymfF S Peptidase M16 inactive domain protein
HFFHMGJP_01762 3.5e-249 ymfH S Peptidase M16
HFFHMGJP_01763 1.1e-139 ymfM S Helix-turn-helix domain
HFFHMGJP_01764 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFFHMGJP_01765 5.3e-226 cinA 3.5.1.42 S Belongs to the CinA family
HFFHMGJP_01766 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HFFHMGJP_01767 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HFFHMGJP_01768 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HFFHMGJP_01769 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFFHMGJP_01770 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HFFHMGJP_01771 3.8e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HFFHMGJP_01772 3.1e-190 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HFFHMGJP_01773 1.8e-30 yajC U Preprotein translocase
HFFHMGJP_01774 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HFFHMGJP_01775 8.3e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HFFHMGJP_01776 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HFFHMGJP_01777 4.1e-43 yrzL S Belongs to the UPF0297 family
HFFHMGJP_01778 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFFHMGJP_01779 6.1e-48 yrzB S Belongs to the UPF0473 family
HFFHMGJP_01780 3.5e-86 cvpA S Colicin V production protein
HFFHMGJP_01781 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HFFHMGJP_01782 6.1e-54 trxA O Belongs to the thioredoxin family
HFFHMGJP_01783 3e-96 yslB S Protein of unknown function (DUF2507)
HFFHMGJP_01784 1.2e-141 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HFFHMGJP_01785 9.5e-101 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HFFHMGJP_01786 5.9e-94 S Phosphoesterase
HFFHMGJP_01787 1.8e-75 ykuL S (CBS) domain
HFFHMGJP_01788 2.3e-153 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HFFHMGJP_01789 3.4e-147 ykuT M mechanosensitive ion channel
HFFHMGJP_01790 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HFFHMGJP_01791 1.1e-27
HFFHMGJP_01792 3.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFFHMGJP_01793 8.4e-182 ccpA K catabolite control protein A
HFFHMGJP_01794 5.8e-136
HFFHMGJP_01795 3.5e-132 yebC K Transcriptional regulatory protein
HFFHMGJP_01796 3.4e-180 comGA NU Type II IV secretion system protein
HFFHMGJP_01797 6e-183 comGB NU type II secretion system
HFFHMGJP_01798 7.1e-47 comGC U competence protein ComGC
HFFHMGJP_01799 9.2e-77 NU general secretion pathway protein
HFFHMGJP_01800 8.4e-42
HFFHMGJP_01801 4.1e-69
HFFHMGJP_01803 4.2e-144 ytxK 2.1.1.72 L N-6 DNA Methylase
HFFHMGJP_01804 5.8e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFFHMGJP_01805 7.7e-114 S Calcineurin-like phosphoesterase
HFFHMGJP_01806 2.7e-94 yutD S Protein of unknown function (DUF1027)
HFFHMGJP_01807 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HFFHMGJP_01808 7e-105 S Protein of unknown function (DUF1461)
HFFHMGJP_01809 5.5e-110 dedA S SNARE-like domain protein
HFFHMGJP_01811 1.5e-36
HFFHMGJP_01812 9.5e-87 S Psort location CytoplasmicMembrane, score
HFFHMGJP_01813 1.1e-83 M biosynthesis protein
HFFHMGJP_01814 2.3e-186 cps3F
HFFHMGJP_01815 6.2e-103 S enterobacterial common antigen metabolic process
HFFHMGJP_01817 4.3e-97 acmD M repeat protein
HFFHMGJP_01818 4.8e-132 M transferase activity, transferring glycosyl groups
HFFHMGJP_01819 1.6e-151 waaB GT4 M Glycosyl transferases group 1
HFFHMGJP_01820 3.3e-240 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HFFHMGJP_01821 8.9e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
HFFHMGJP_01822 3.8e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
HFFHMGJP_01823 2.3e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HFFHMGJP_01824 2.3e-147 cps1D M Domain of unknown function (DUF4422)
HFFHMGJP_01825 2.8e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
HFFHMGJP_01826 4.9e-31
HFFHMGJP_01827 9.5e-33 S Protein of unknown function (DUF2922)
HFFHMGJP_01828 1.8e-151 yihY S Belongs to the UPF0761 family
HFFHMGJP_01829 5.3e-281 yjeM E Amino Acid
HFFHMGJP_01830 1.3e-257 E Arginine ornithine antiporter
HFFHMGJP_01831 1.7e-220 arcT 2.6.1.1 E Aminotransferase
HFFHMGJP_01832 8.2e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFFHMGJP_01833 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFFHMGJP_01834 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HFFHMGJP_01835 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HFFHMGJP_01836 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HFFHMGJP_01837 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFFHMGJP_01838 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HFFHMGJP_01839 1e-215 nusA K Participates in both transcription termination and antitermination
HFFHMGJP_01840 1e-44 ylxR K Protein of unknown function (DUF448)
HFFHMGJP_01841 4.5e-49 ylxQ J ribosomal protein
HFFHMGJP_01842 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HFFHMGJP_01843 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HFFHMGJP_01844 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFFHMGJP_01845 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HFFHMGJP_01846 2e-64
HFFHMGJP_01847 1.8e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HFFHMGJP_01848 1.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HFFHMGJP_01849 0.0 dnaK O Heat shock 70 kDa protein
HFFHMGJP_01850 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HFFHMGJP_01851 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HFFHMGJP_01852 1.1e-69 3.6.4.12 L Belongs to the 'phage' integrase family
HFFHMGJP_01853 1.7e-27 3.6.4.12 L Belongs to the 'phage' integrase family
HFFHMGJP_01855 8.2e-17
HFFHMGJP_01856 7.6e-115 3.4.21.88 K Peptidase S24-like
HFFHMGJP_01859 2e-14
HFFHMGJP_01860 1.2e-197 S OPT oligopeptide transporter protein
HFFHMGJP_01861 1e-23 S Coenzyme PQQ synthesis protein D (PqqD)
HFFHMGJP_01862 5.3e-275 pipD E Dipeptidase
HFFHMGJP_01863 3.6e-199 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HFFHMGJP_01864 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HFFHMGJP_01866 2.8e-57
HFFHMGJP_01867 2.7e-177 prmA J Ribosomal protein L11 methyltransferase
HFFHMGJP_01868 1.2e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HFFHMGJP_01869 1.3e-51
HFFHMGJP_01870 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFFHMGJP_01871 2.4e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HFFHMGJP_01872 1.7e-164 yniA G Phosphotransferase enzyme family
HFFHMGJP_01873 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HFFHMGJP_01874 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HFFHMGJP_01875 7e-265 glnPH2 P ABC transporter permease
HFFHMGJP_01876 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HFFHMGJP_01877 7.3e-69 yqeY S YqeY-like protein
HFFHMGJP_01878 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HFFHMGJP_01879 1.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HFFHMGJP_01880 9.2e-264 argH 4.3.2.1 E argininosuccinate lyase
HFFHMGJP_01881 6.7e-88 bioY S BioY family
HFFHMGJP_01882 5.1e-176 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HFFHMGJP_01883 6.9e-184 phoH T phosphate starvation-inducible protein PhoH
HFFHMGJP_01884 2.1e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HFFHMGJP_01885 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HFFHMGJP_01886 5.1e-170 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFFHMGJP_01887 2.6e-146 recO L Involved in DNA repair and RecF pathway recombination
HFFHMGJP_01888 7.7e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HFFHMGJP_01889 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HFFHMGJP_01890 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HFFHMGJP_01891 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HFFHMGJP_01892 4.8e-221 patA 2.6.1.1 E Aminotransferase
HFFHMGJP_01893 2.4e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
HFFHMGJP_01894 7.6e-157 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFFHMGJP_01895 1.1e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HFFHMGJP_01896 2.3e-30 S Protein of unknown function (DUF2929)
HFFHMGJP_01897 0.0 dnaE 2.7.7.7 L DNA polymerase
HFFHMGJP_01898 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HFFHMGJP_01899 9.3e-169 cvfB S S1 domain
HFFHMGJP_01900 1.7e-165 xerD D recombinase XerD
HFFHMGJP_01901 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HFFHMGJP_01902 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFFHMGJP_01903 2.2e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFFHMGJP_01904 5.8e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HFFHMGJP_01905 2e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HFFHMGJP_01906 3.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
HFFHMGJP_01907 4e-270 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HFFHMGJP_01908 8.5e-14 M Lysin motif
HFFHMGJP_01909 9.9e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HFFHMGJP_01910 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HFFHMGJP_01911 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HFFHMGJP_01912 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HFFHMGJP_01913 6.3e-235 S Tetratricopeptide repeat protein
HFFHMGJP_01914 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HFFHMGJP_01915 0.0 yfmR S ABC transporter, ATP-binding protein
HFFHMGJP_01916 4.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HFFHMGJP_01917 7.4e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFFHMGJP_01918 5.3e-113 hlyIII S protein, hemolysin III
HFFHMGJP_01919 3.1e-153 DegV S EDD domain protein, DegV family
HFFHMGJP_01920 9.5e-172 ypmR E lipolytic protein G-D-S-L family
HFFHMGJP_01921 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HFFHMGJP_01922 4.4e-35 yozE S Belongs to the UPF0346 family
HFFHMGJP_01923 6.4e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HFFHMGJP_01924 3.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFFHMGJP_01925 2.7e-160 dprA LU DNA protecting protein DprA
HFFHMGJP_01926 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HFFHMGJP_01927 3.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
HFFHMGJP_01928 1.2e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HFFHMGJP_01929 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFFHMGJP_01930 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HFFHMGJP_01931 4.9e-84 F NUDIX domain
HFFHMGJP_01932 2.3e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HFFHMGJP_01933 4.1e-68 yqkB S Belongs to the HesB IscA family
HFFHMGJP_01934 2.7e-49
HFFHMGJP_01936 1.6e-88 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HFFHMGJP_01937 8.7e-63 asp S Asp23 family, cell envelope-related function
HFFHMGJP_01938 6.1e-25
HFFHMGJP_01939 3e-93
HFFHMGJP_01940 7.7e-288 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HFFHMGJP_01941 4.4e-183 K Transcriptional regulator, LacI family
HFFHMGJP_01942 5.3e-232 gntT EG Gluconate
HFFHMGJP_01943 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HFFHMGJP_01944 2.9e-96 K Acetyltransferase (GNAT) domain
HFFHMGJP_01945 4.2e-47
HFFHMGJP_01946 0.0 nylA 3.5.1.4 J Belongs to the amidase family
HFFHMGJP_01947 2.2e-44
HFFHMGJP_01948 3.3e-54 yhaI S Protein of unknown function (DUF805)
HFFHMGJP_01949 1.3e-10 yfjM S Protein of unknown function DUF262
HFFHMGJP_01950 4.5e-21
HFFHMGJP_01951 0.0 yeeA V Type II restriction enzyme, methylase subunits
HFFHMGJP_01952 0.0 yeeB L DEAD-like helicases superfamily
HFFHMGJP_01953 3e-133 pstS P T5orf172
HFFHMGJP_01954 2.4e-34 higA K addiction module antidote protein HigA
HFFHMGJP_01955 5.5e-21
HFFHMGJP_01956 0.0 L PLD-like domain
HFFHMGJP_01958 3.1e-178 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HFFHMGJP_01959 4.5e-194 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFFHMGJP_01960 3.7e-100 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HFFHMGJP_01961 8.8e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HFFHMGJP_01962 4e-189 L PFAM Integrase catalytic region
HFFHMGJP_01964 8.6e-195 nss M transferase activity, transferring glycosyl groups
HFFHMGJP_01965 1.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HFFHMGJP_01966 1.1e-286 M transferase activity, transferring glycosyl groups
HFFHMGJP_01967 2.6e-288 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HFFHMGJP_01968 9.1e-164 asp3 S Accessory Sec secretory system ASP3
HFFHMGJP_01969 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HFFHMGJP_01970 7.3e-294 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HFFHMGJP_01971 3.5e-260 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HFFHMGJP_01973 0.0 GT2,GT4 M Pfam:DUF1792
HFFHMGJP_01974 0.0 M family 8
HFFHMGJP_01975 4e-284 GT2,GT4 M family 8
HFFHMGJP_01977 7.8e-86
HFFHMGJP_01978 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HFFHMGJP_01979 4.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFFHMGJP_01980 3.6e-171 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFFHMGJP_01981 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFFHMGJP_01982 1e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HFFHMGJP_01983 2.5e-264 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HFFHMGJP_01984 9.8e-67 yabR J RNA binding
HFFHMGJP_01985 5.6e-56 divIC D Septum formation initiator
HFFHMGJP_01986 2.1e-39 yabO J S4 domain protein
HFFHMGJP_01987 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFFHMGJP_01988 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HFFHMGJP_01989 1.8e-113 S (CBS) domain
HFFHMGJP_01990 3.1e-147 tesE Q hydratase
HFFHMGJP_01991 6.8e-242 codA 3.5.4.1 F cytosine deaminase
HFFHMGJP_01992 1.2e-250 U Belongs to the purine-cytosine permease (2.A.39) family
HFFHMGJP_01993 9.4e-62 L Toxic component of a toxin-antitoxin (TA) module
HFFHMGJP_01994 4.8e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFFHMGJP_01995 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HFFHMGJP_01997 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFFHMGJP_01998 3e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HFFHMGJP_01999 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HFFHMGJP_02000 1.2e-254 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HFFHMGJP_02001 2.3e-96 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFFHMGJP_02009 2.6e-291 L Transposase IS66 family
HFFHMGJP_02010 1.7e-65 XK27_01125 L PFAM IS66 Orf2 family protein
HFFHMGJP_02012 2.4e-55 L Helix-turn-helix domain
HFFHMGJP_02013 7.2e-79 L hmm pf00665
HFFHMGJP_02015 6.1e-157 1.6.5.2 GM NAD(P)H-binding
HFFHMGJP_02016 1.8e-75 K Transcriptional regulator
HFFHMGJP_02017 3.1e-159 proX M ABC transporter, substrate-binding protein, QAT family
HFFHMGJP_02018 8.2e-109 proWZ P ABC transporter permease
HFFHMGJP_02019 2.3e-139 proV E ABC transporter, ATP-binding protein
HFFHMGJP_02020 1.4e-102 proW P ABC transporter, permease protein
HFFHMGJP_02021 5.7e-79 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HFFHMGJP_02022 1e-251 clcA P chloride
HFFHMGJP_02023 5.7e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HFFHMGJP_02024 3.1e-103 metI P ABC transporter permease
HFFHMGJP_02025 4.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFFHMGJP_02026 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HFFHMGJP_02027 3.6e-121 scrR3 K Transcriptional regulator, LacI family
HFFHMGJP_02028 4e-156 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HFFHMGJP_02029 2.6e-42 S Sugar efflux transporter for intercellular exchange
HFFHMGJP_02030 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HFFHMGJP_02031 1.4e-220 norA EGP Major facilitator Superfamily
HFFHMGJP_02032 4.3e-43 1.3.5.4 S FMN binding
HFFHMGJP_02033 8.4e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFFHMGJP_02034 1.8e-265 yfnA E amino acid
HFFHMGJP_02035 3.1e-256 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFFHMGJP_02037 3.1e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HFFHMGJP_02038 0.0 helD 3.6.4.12 L DNA helicase
HFFHMGJP_02039 6.3e-81 ndk 2.7.4.6 F Belongs to the NDK family
HFFHMGJP_02040 5.5e-183 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HFFHMGJP_02041 1.3e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HFFHMGJP_02042 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HFFHMGJP_02043 2.8e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HFFHMGJP_02044 1.4e-178
HFFHMGJP_02045 5.2e-130 cobB K SIR2 family
HFFHMGJP_02047 4e-161 yunF F Protein of unknown function DUF72
HFFHMGJP_02048 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFFHMGJP_02049 1.9e-155 tatD L hydrolase, TatD family
HFFHMGJP_02050 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HFFHMGJP_02051 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HFFHMGJP_02052 6.8e-37 veg S Biofilm formation stimulator VEG
HFFHMGJP_02053 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HFFHMGJP_02054 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HFFHMGJP_02055 2.2e-122 fhuC P ABC transporter
HFFHMGJP_02056 1.6e-127 znuB U ABC 3 transport family
HFFHMGJP_02057 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HFFHMGJP_02058 1.8e-240 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HFFHMGJP_02059 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFFHMGJP_02060 5.6e-50
HFFHMGJP_02061 4.6e-204 rarA L recombination factor protein RarA
HFFHMGJP_02062 1.9e-147 yxeH S hydrolase
HFFHMGJP_02063 5.9e-271 ywfO S HD domain protein
HFFHMGJP_02064 1.3e-151 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HFFHMGJP_02065 1.2e-67 ywiB S Domain of unknown function (DUF1934)
HFFHMGJP_02066 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HFFHMGJP_02067 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HFFHMGJP_02068 1.4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFFHMGJP_02069 4.6e-41 rpmE2 J Ribosomal protein L31
HFFHMGJP_02070 1.1e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HFFHMGJP_02071 2e-166 S Alpha/beta hydrolase of unknown function (DUF915)
HFFHMGJP_02072 5.1e-125 srtA 3.4.22.70 M sortase family
HFFHMGJP_02073 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HFFHMGJP_02074 6.1e-159 3.2.1.55 GH51 G Right handed beta helix region
HFFHMGJP_02075 2.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HFFHMGJP_02076 1.7e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HFFHMGJP_02077 5.4e-121 pgm3 G Belongs to the phosphoglycerate mutase family
HFFHMGJP_02078 6.8e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFFHMGJP_02079 7e-93 lemA S LemA family
HFFHMGJP_02080 1.5e-158 htpX O Belongs to the peptidase M48B family
HFFHMGJP_02081 1.3e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HFFHMGJP_02082 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HFFHMGJP_02083 0.0 sprD D Domain of Unknown Function (DUF1542)
HFFHMGJP_02084 9e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
HFFHMGJP_02085 2.4e-55 L Helix-turn-helix domain
HFFHMGJP_02086 7.2e-79 L hmm pf00665
HFFHMGJP_02087 1e-151
HFFHMGJP_02088 3e-179
HFFHMGJP_02089 6.5e-90 dut S Protein conserved in bacteria
HFFHMGJP_02092 4.4e-112 K Transcriptional regulator
HFFHMGJP_02093 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HFFHMGJP_02094 7.4e-55 ysxB J Cysteine protease Prp
HFFHMGJP_02095 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HFFHMGJP_02096 3.4e-129 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HFFHMGJP_02097 2.1e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HFFHMGJP_02098 1.4e-116 J 2'-5' RNA ligase superfamily
HFFHMGJP_02099 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HFFHMGJP_02100 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HFFHMGJP_02101 8e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HFFHMGJP_02102 3.2e-221 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFFHMGJP_02103 2.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HFFHMGJP_02104 1.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HFFHMGJP_02105 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HFFHMGJP_02106 3.3e-77 argR K Regulates arginine biosynthesis genes
HFFHMGJP_02107 3.3e-263 recN L May be involved in recombinational repair of damaged DNA
HFFHMGJP_02108 1.7e-54
HFFHMGJP_02109 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HFFHMGJP_02110 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HFFHMGJP_02111 2.4e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFFHMGJP_02112 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFFHMGJP_02113 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HFFHMGJP_02114 2.8e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HFFHMGJP_02115 2.9e-131 stp 3.1.3.16 T phosphatase
HFFHMGJP_02116 0.0 KLT serine threonine protein kinase
HFFHMGJP_02117 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HFFHMGJP_02118 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HFFHMGJP_02119 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HFFHMGJP_02120 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HFFHMGJP_02121 4.7e-58 asp S Asp23 family, cell envelope-related function
HFFHMGJP_02122 0.0 yloV S DAK2 domain fusion protein YloV
HFFHMGJP_02123 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFFHMGJP_02124 2.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HFFHMGJP_02125 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFFHMGJP_02126 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HFFHMGJP_02127 0.0 smc D Required for chromosome condensation and partitioning
HFFHMGJP_02128 5e-178 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HFFHMGJP_02129 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HFFHMGJP_02130 7.9e-250 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFFHMGJP_02131 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HFFHMGJP_02132 2e-39 ylqC S Belongs to the UPF0109 family
HFFHMGJP_02133 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFFHMGJP_02134 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HFFHMGJP_02135 3.4e-261 yfnA E amino acid
HFFHMGJP_02136 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HFFHMGJP_02137 1.5e-208 L Belongs to the 'phage' integrase family
HFFHMGJP_02138 4.5e-49
HFFHMGJP_02139 6.6e-31 S Membrane
HFFHMGJP_02141 1.8e-62 S Short C-terminal domain
HFFHMGJP_02142 1.6e-70 S Pfam:DUF955
HFFHMGJP_02143 8.4e-33 3.4.21.88 K Helix-turn-helix domain
HFFHMGJP_02146 8.5e-70 S Phage antirepressor protein KilAC domain
HFFHMGJP_02149 1.8e-17
HFFHMGJP_02152 2e-22
HFFHMGJP_02153 3.2e-14 K Cro/C1-type HTH DNA-binding domain
HFFHMGJP_02162 3.2e-159 recT L RecT family
HFFHMGJP_02163 9.3e-163 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HFFHMGJP_02164 1.8e-45 ybl78 L Conserved phage C-terminus (Phg_2220_C)
HFFHMGJP_02165 3.3e-26
HFFHMGJP_02168 6.8e-50 S ORF6C domain
HFFHMGJP_02171 2.5e-14
HFFHMGJP_02172 5.7e-63 rusA L Endodeoxyribonuclease RusA
HFFHMGJP_02175 1.1e-36
HFFHMGJP_02181 7.8e-69 S Domain of unknown function (DUF4417)
HFFHMGJP_02183 3.1e-116 xtmA L Terminase small subunit
HFFHMGJP_02184 4.9e-219 S Terminase-like family
HFFHMGJP_02185 2.4e-217 S Phage portal protein, SPP1 Gp6-like
HFFHMGJP_02186 5.2e-150 S Phage Mu protein F like protein
HFFHMGJP_02187 3.4e-51 S Domain of unknown function (DUF4355)
HFFHMGJP_02188 1.4e-52
HFFHMGJP_02189 1.6e-167 S Phage major capsid protein E
HFFHMGJP_02190 1.7e-35
HFFHMGJP_02191 1.2e-58
HFFHMGJP_02192 2.5e-79
HFFHMGJP_02193 4.6e-53
HFFHMGJP_02194 1.7e-71 S Phage tail tube protein, TTP
HFFHMGJP_02195 9e-58
HFFHMGJP_02196 1.5e-32
HFFHMGJP_02197 0.0 M Phage tail tape measure protein TP901
HFFHMGJP_02198 4.9e-21
HFFHMGJP_02199 0.0 GT2,GT4 LM gp58-like protein
HFFHMGJP_02201 4.8e-12
HFFHMGJP_02202 7.4e-55 S Bacteriophage holin family
HFFHMGJP_02203 8.6e-65 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HFFHMGJP_02204 3.3e-180 M Glycosyl hydrolases family 25
HFFHMGJP_02205 4.7e-10 T PFAM SpoVT AbrB
HFFHMGJP_02206 6e-23 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HFFHMGJP_02207 7.7e-35
HFFHMGJP_02208 3.5e-52 S Mazg nucleotide pyrophosphohydrolase
HFFHMGJP_02209 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
HFFHMGJP_02210 7.3e-83
HFFHMGJP_02211 7.9e-188 lacR K Transcriptional regulator
HFFHMGJP_02212 7.2e-79 L hmm pf00665
HFFHMGJP_02213 2.4e-55 L Helix-turn-helix domain
HFFHMGJP_02214 4.1e-50 S Iron-sulfur cluster assembly protein
HFFHMGJP_02215 1.8e-98 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HFFHMGJP_02216 3.3e-155 P Belongs to the nlpA lipoprotein family
HFFHMGJP_02217 3.9e-12
HFFHMGJP_02218 8.2e-201 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
HFFHMGJP_02219 7.2e-79 L hmm pf00665
HFFHMGJP_02220 2.4e-55 L Helix-turn-helix domain
HFFHMGJP_02221 1e-262 S Putative peptidoglycan binding domain
HFFHMGJP_02222 1.8e-124 yciB M ErfK YbiS YcfS YnhG
HFFHMGJP_02224 6.5e-102
HFFHMGJP_02225 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HFFHMGJP_02226 3.6e-125 S Alpha beta hydrolase
HFFHMGJP_02227 1.6e-205 gldA 1.1.1.6 C dehydrogenase
HFFHMGJP_02228 1.9e-132 ydiN G Major Facilitator Superfamily
HFFHMGJP_02229 3.9e-127 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HFFHMGJP_02230 8.5e-54 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HFFHMGJP_02231 1e-12 ydiN 5.4.99.5 G Major Facilitator
HFFHMGJP_02232 1e-162 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HFFHMGJP_02233 3.8e-35
HFFHMGJP_02234 5.4e-157 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HFFHMGJP_02235 3.5e-109 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HFFHMGJP_02236 3.4e-35 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HFFHMGJP_02237 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HFFHMGJP_02238 1.3e-41
HFFHMGJP_02239 6.5e-127 pgm3 3.1.3.73 G phosphoglycerate mutase family
HFFHMGJP_02240 2.1e-285 S C4-dicarboxylate anaerobic carrier
HFFHMGJP_02241 4.1e-251 nhaC C Na H antiporter NhaC
HFFHMGJP_02242 7.3e-242 pbuX F xanthine permease
HFFHMGJP_02243 3.2e-281 pipD E Dipeptidase
HFFHMGJP_02244 9.7e-169 corA P CorA-like Mg2+ transporter protein
HFFHMGJP_02245 1.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HFFHMGJP_02246 2.3e-131 terC P membrane
HFFHMGJP_02247 2.1e-54 trxA O Belongs to the thioredoxin family
HFFHMGJP_02248 6.4e-238 mepA V MATE efflux family protein
HFFHMGJP_02249 1.5e-92 M domain protein
HFFHMGJP_02250 8.9e-56 K Transcriptional regulator, ArsR family
HFFHMGJP_02251 5.9e-92 P Cadmium resistance transporter
HFFHMGJP_02252 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
HFFHMGJP_02253 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HFFHMGJP_02254 3.7e-182 ABC-SBP S ABC transporter
HFFHMGJP_02255 9.9e-226 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HFFHMGJP_02256 1.7e-73 M PFAM NLP P60 protein
HFFHMGJP_02257 1.4e-99 S Protein of unknown function (DUF3278)
HFFHMGJP_02258 6.7e-31 WQ51_00220 K Helix-turn-helix domain
HFFHMGJP_02259 1.3e-48
HFFHMGJP_02260 1.9e-273 S ABC transporter, ATP-binding protein
HFFHMGJP_02261 5.9e-143 S Putative ABC-transporter type IV
HFFHMGJP_02262 2e-106 NU mannosyl-glycoprotein
HFFHMGJP_02263 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
HFFHMGJP_02264 4.1e-231 S Uncharacterized protein conserved in bacteria (DUF2325)
HFFHMGJP_02265 2.9e-204 nrnB S DHHA1 domain
HFFHMGJP_02267 1.7e-12 K Helix-turn-helix domain
HFFHMGJP_02271 6.3e-50
HFFHMGJP_02272 7.3e-136 2.1.1.72 D peptidase
HFFHMGJP_02273 8.7e-19 S Domain of unknown function (DUF4767)
HFFHMGJP_02274 6.8e-53
HFFHMGJP_02275 3.2e-116 yrkL S Flavodoxin-like fold
HFFHMGJP_02277 5.4e-65 yeaO S Protein of unknown function, DUF488
HFFHMGJP_02278 3.4e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HFFHMGJP_02279 2.1e-205 3.1.3.1 S associated with various cellular activities
HFFHMGJP_02280 1.5e-231 S Putative metallopeptidase domain
HFFHMGJP_02281 1.8e-47
HFFHMGJP_02282 5.3e-172 L transposase, IS605 OrfB family
HFFHMGJP_02283 0.0 pepO 3.4.24.71 O Peptidase family M13
HFFHMGJP_02284 3.3e-104 K Helix-turn-helix XRE-family like proteins
HFFHMGJP_02285 2.7e-88 ymdB S Macro domain protein
HFFHMGJP_02286 3.3e-198 EGP Major facilitator Superfamily
HFFHMGJP_02287 3.8e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFFHMGJP_02288 2.5e-43 K helix_turn_helix, mercury resistance
HFFHMGJP_02289 8.8e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HFFHMGJP_02290 6.9e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HFFHMGJP_02291 0.0 ysaB V FtsX-like permease family
HFFHMGJP_02292 2.6e-135 macB2 V ABC transporter, ATP-binding protein
HFFHMGJP_02293 7.4e-183 T PhoQ Sensor
HFFHMGJP_02294 1.4e-124 K response regulator
HFFHMGJP_02295 8.6e-156 ytbE 1.1.1.346 S Aldo keto reductase
HFFHMGJP_02296 1.8e-136 pnuC H nicotinamide mononucleotide transporter
HFFHMGJP_02297 7.5e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HFFHMGJP_02298 1.9e-203
HFFHMGJP_02299 9.1e-53
HFFHMGJP_02300 9.1e-36
HFFHMGJP_02301 6.3e-93 yxkA S Phosphatidylethanolamine-binding protein
HFFHMGJP_02302 2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
HFFHMGJP_02303 5.6e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HFFHMGJP_02304 2.9e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HFFHMGJP_02305 9e-286 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HFFHMGJP_02306 1.2e-180 galR K Transcriptional regulator
HFFHMGJP_02307 7e-99 dedA 3.1.3.1 S SNARE associated Golgi protein
HFFHMGJP_02308 3e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HFFHMGJP_02309 1.5e-80 K AsnC family
HFFHMGJP_02310 3.3e-80 uspA T universal stress protein
HFFHMGJP_02311 3.8e-49 ltrA S Bacterial low temperature requirement A protein (LtrA)
HFFHMGJP_02312 8.3e-63 ltrA S Bacterial low temperature requirement A protein (LtrA)
HFFHMGJP_02313 0.0 lacS G Transporter
HFFHMGJP_02314 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HFFHMGJP_02315 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HFFHMGJP_02316 8.9e-193 yeaN P Transporter, major facilitator family protein
HFFHMGJP_02317 1.2e-73 S 3-demethylubiquinone-9 3-methyltransferase
HFFHMGJP_02318 1.3e-84 nrdI F Belongs to the NrdI family
HFFHMGJP_02319 2.3e-240 yhdP S Transporter associated domain
HFFHMGJP_02320 1.5e-155 ypdB V (ABC) transporter
HFFHMGJP_02321 4.3e-89 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
HFFHMGJP_02322 4e-90 M1-874 K Domain of unknown function (DUF1836)
HFFHMGJP_02323 2.1e-76 yybA 2.3.1.57 K Transcriptional regulator
HFFHMGJP_02324 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
HFFHMGJP_02325 6.9e-169 S AI-2E family transporter
HFFHMGJP_02326 2.5e-155 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HFFHMGJP_02327 3.9e-162
HFFHMGJP_02328 1.6e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HFFHMGJP_02329 7.8e-149 eutJ E Hsp70 protein
HFFHMGJP_02330 4.7e-199 K helix_turn_helix, arabinose operon control protein
HFFHMGJP_02331 6.2e-42 pduA_4 CQ BMC
HFFHMGJP_02332 2.7e-134 pduB E BMC
HFFHMGJP_02333 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HFFHMGJP_02334 1.1e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HFFHMGJP_02335 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
HFFHMGJP_02336 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
HFFHMGJP_02337 4.2e-59 pduH S Dehydratase medium subunit
HFFHMGJP_02338 1.4e-72 pduK CQ BMC
HFFHMGJP_02339 2.2e-42 pduA_4 CQ BMC
HFFHMGJP_02340 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HFFHMGJP_02341 6.4e-90 S Putative propanediol utilisation
HFFHMGJP_02342 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HFFHMGJP_02343 2.8e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HFFHMGJP_02344 7.4e-80 pduO S Haem-degrading
HFFHMGJP_02345 6.8e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HFFHMGJP_02346 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
HFFHMGJP_02347 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFFHMGJP_02348 5.5e-56 pduU E BMC
HFFHMGJP_02349 1.4e-147 3.1.3.48 T Pfam:Y_phosphatase3C
HFFHMGJP_02350 6.5e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
HFFHMGJP_02351 6.7e-80 P Cadmium resistance transporter
HFFHMGJP_02352 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
HFFHMGJP_02353 1.9e-77 fld C Flavodoxin
HFFHMGJP_02354 6.6e-156 XK27_04590 S NADPH-dependent FMN reductase
HFFHMGJP_02355 1.1e-101 cobO 2.5.1.17 S Cobalamin adenosyltransferase
HFFHMGJP_02356 2.1e-207 cobD 4.1.1.81 E Aminotransferase class I and II
HFFHMGJP_02357 1e-262 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
HFFHMGJP_02358 5.7e-180 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HFFHMGJP_02359 9.2e-124 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
HFFHMGJP_02360 4.3e-206 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HFFHMGJP_02361 6.3e-108 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFFHMGJP_02362 1.7e-96 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
HFFHMGJP_02363 2.9e-134 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFFHMGJP_02364 5.5e-192 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
HFFHMGJP_02365 1.3e-131 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFFHMGJP_02366 6.4e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
HFFHMGJP_02367 4e-259 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFFHMGJP_02368 2.6e-146 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
HFFHMGJP_02369 5.7e-124 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
HFFHMGJP_02370 2.4e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HFFHMGJP_02371 4.3e-52 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HFFHMGJP_02372 2.9e-117 cbiQ P Cobalt transport protein
HFFHMGJP_02373 1.7e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
HFFHMGJP_02374 5.1e-276 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
HFFHMGJP_02375 6.7e-78 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
HFFHMGJP_02376 2.3e-229 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HFFHMGJP_02377 8.5e-165 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HFFHMGJP_02378 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
HFFHMGJP_02379 1.4e-250 hemL 5.4.3.8 H Aminotransferase class-III
HFFHMGJP_02380 7.8e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
HFFHMGJP_02381 9.9e-135 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HFFHMGJP_02382 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
HFFHMGJP_02383 5.8e-129 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HFFHMGJP_02384 6.5e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
HFFHMGJP_02385 9.6e-62 S Domain of unknown function (DUF4430)
HFFHMGJP_02386 3.4e-81 S ECF transporter, substrate-specific component
HFFHMGJP_02387 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HFFHMGJP_02388 1.2e-308 lmrA V ABC transporter, ATP-binding protein
HFFHMGJP_02389 0.0 yfiC V ABC transporter
HFFHMGJP_02390 4.9e-284 pipD E Dipeptidase
HFFHMGJP_02391 4.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFFHMGJP_02392 1.6e-134 gntR K UbiC transcription regulator-associated domain protein
HFFHMGJP_02393 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HFFHMGJP_02394 7.2e-79 L hmm pf00665
HFFHMGJP_02395 2.4e-55 L Helix-turn-helix domain
HFFHMGJP_02396 6.8e-215 5.4.2.7 G Metalloenzyme superfamily
HFFHMGJP_02397 0.0 cadA P P-type ATPase
HFFHMGJP_02398 1.2e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HFFHMGJP_02399 4.4e-129
HFFHMGJP_02400 1.8e-53 S Sugar efflux transporter for intercellular exchange
HFFHMGJP_02401 4.7e-244 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HFFHMGJP_02402 3.2e-121 L hmm pf00665
HFFHMGJP_02403 1e-125 L Helix-turn-helix domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)