ORF_ID e_value Gene_name EC_number CAZy COGs Description
NLLIHHGE_00002 2.5e-29 L PFAM transposase IS200-family protein
NLLIHHGE_00014 8.4e-30 L PFAM transposase IS200-family protein
NLLIHHGE_00015 1.8e-113 S (CBS) domain
NLLIHHGE_00016 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NLLIHHGE_00017 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NLLIHHGE_00018 2.1e-39 yabO J S4 domain protein
NLLIHHGE_00019 5.6e-56 divIC D Septum formation initiator
NLLIHHGE_00020 9.8e-67 yabR J RNA binding
NLLIHHGE_00021 3e-262 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NLLIHHGE_00022 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NLLIHHGE_00023 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NLLIHHGE_00024 3e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NLLIHHGE_00025 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NLLIHHGE_00026 4.7e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NLLIHHGE_00027 7.8e-86
NLLIHHGE_00029 5.5e-69 K Bacterial transcriptional regulator
NLLIHHGE_00030 5.5e-161 K LysR substrate binding domain protein
NLLIHHGE_00031 1.5e-83 C Flavodoxin
NLLIHHGE_00032 3.8e-80 yphH S Cupin domain
NLLIHHGE_00033 4.5e-74 yeaL S UPF0756 membrane protein
NLLIHHGE_00034 1.2e-242 EGP Major facilitator Superfamily
NLLIHHGE_00035 1.9e-74 copY K Copper transport repressor CopY TcrY
NLLIHHGE_00036 8.5e-246 yhdP S Transporter associated domain
NLLIHHGE_00037 0.0 ubiB S ABC1 family
NLLIHHGE_00038 2.8e-143 S DUF218 domain
NLLIHHGE_00039 4.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NLLIHHGE_00040 2.4e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLLIHHGE_00041 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLLIHHGE_00042 0.0 uvrA3 L excinuclease ABC, A subunit
NLLIHHGE_00043 5.1e-122 S SNARE associated Golgi protein
NLLIHHGE_00044 1.3e-229 N Uncharacterized conserved protein (DUF2075)
NLLIHHGE_00045 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NLLIHHGE_00047 5.1e-254 yifK E Amino acid permease
NLLIHHGE_00048 6.5e-151 endA V DNA/RNA non-specific endonuclease
NLLIHHGE_00049 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLLIHHGE_00050 3.5e-42 ybaN S Protein of unknown function (DUF454)
NLLIHHGE_00051 4.1e-72 S Protein of unknown function (DUF3290)
NLLIHHGE_00052 1.2e-112 yviA S Protein of unknown function (DUF421)
NLLIHHGE_00053 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
NLLIHHGE_00054 7e-19
NLLIHHGE_00055 4e-89 ntd 2.4.2.6 F Nucleoside
NLLIHHGE_00056 4.8e-151 3.1.3.102, 3.1.3.104 S hydrolase
NLLIHHGE_00057 6.8e-49 yrvD S Pfam:DUF1049
NLLIHHGE_00059 1.9e-08
NLLIHHGE_00062 2.9e-30 L PFAM transposase IS200-family protein
NLLIHHGE_00065 2.6e-217 L Integrase core domain
NLLIHHGE_00066 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_00067 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NLLIHHGE_00068 2.6e-217 L Integrase core domain
NLLIHHGE_00069 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_00072 2.7e-206 2.7.13.3 T GHKL domain
NLLIHHGE_00073 1e-118 K LytTr DNA-binding domain
NLLIHHGE_00074 1e-24
NLLIHHGE_00075 7.6e-20 relB L Addiction module antitoxin, RelB DinJ family
NLLIHHGE_00076 6.3e-90 XK27_08850 J Aminoacyl-tRNA editing domain
NLLIHHGE_00077 1e-56 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NLLIHHGE_00078 2.2e-193 V Beta-lactamase
NLLIHHGE_00079 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NLLIHHGE_00080 1.2e-123 yhiD S MgtC family
NLLIHHGE_00081 6.7e-110 S GyrI-like small molecule binding domain
NLLIHHGE_00083 8.3e-122 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NLLIHHGE_00084 4.2e-50 azlD E Branched-chain amino acid transport
NLLIHHGE_00085 3.1e-119 azlC E azaleucine resistance protein AzlC
NLLIHHGE_00086 6.5e-257 K Aminotransferase class I and II
NLLIHHGE_00087 2e-299 S amidohydrolase
NLLIHHGE_00088 1.6e-125 S Alpha/beta hydrolase of unknown function (DUF915)
NLLIHHGE_00089 6e-148 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLIHHGE_00091 1.8e-161 S reductase
NLLIHHGE_00092 4.1e-89 2.3.1.183 M Acetyltransferase GNAT family
NLLIHHGE_00093 3.8e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NLLIHHGE_00094 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
NLLIHHGE_00095 1.1e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NLLIHHGE_00096 0.0 asnB 6.3.5.4 E Asparagine synthase
NLLIHHGE_00097 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NLLIHHGE_00098 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NLLIHHGE_00099 2.7e-132 jag S R3H domain protein
NLLIHHGE_00100 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLLIHHGE_00101 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NLLIHHGE_00102 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NLLIHHGE_00103 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NLLIHHGE_00104 1.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NLLIHHGE_00105 7.4e-125 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NLLIHHGE_00106 1.7e-34 yaaA S S4 domain protein YaaA
NLLIHHGE_00107 4.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NLLIHHGE_00108 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLLIHHGE_00109 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NLLIHHGE_00110 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
NLLIHHGE_00111 2.2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLLIHHGE_00112 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NLLIHHGE_00113 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NLLIHHGE_00114 2e-74 rplI J Binds to the 23S rRNA
NLLIHHGE_00115 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NLLIHHGE_00116 8.4e-205 yttB EGP Major facilitator Superfamily
NLLIHHGE_00117 8.5e-59
NLLIHHGE_00118 4.3e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
NLLIHHGE_00119 1.9e-74 K DNA-binding helix-turn-helix protein
NLLIHHGE_00121 1.2e-73 K helix_turn_helix multiple antibiotic resistance protein
NLLIHHGE_00122 4.8e-311 lmrA 3.6.3.44 V ABC transporter
NLLIHHGE_00124 3.1e-130 K response regulator
NLLIHHGE_00125 0.0 vicK 2.7.13.3 T Histidine kinase
NLLIHHGE_00126 6e-249 yycH S YycH protein
NLLIHHGE_00127 8.4e-151 yycI S YycH protein
NLLIHHGE_00128 4.5e-154 vicX 3.1.26.11 S domain protein
NLLIHHGE_00129 1.2e-217 htrA 3.4.21.107 O serine protease
NLLIHHGE_00130 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NLLIHHGE_00131 3.6e-177 ABC-SBP S ABC transporter
NLLIHHGE_00132 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NLLIHHGE_00134 2.4e-95 S reductase
NLLIHHGE_00135 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NLLIHHGE_00136 7.5e-155 glcU U sugar transport
NLLIHHGE_00137 2.7e-148 E Glyoxalase-like domain
NLLIHHGE_00138 1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLLIHHGE_00139 4.9e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NLLIHHGE_00140 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NLLIHHGE_00141 2.2e-128 V ABC transporter
NLLIHHGE_00142 2.1e-214 bacI V MacB-like periplasmic core domain
NLLIHHGE_00143 8.1e-32
NLLIHHGE_00144 3.4e-258 S Putative peptidoglycan binding domain
NLLIHHGE_00146 8.7e-54 L An automated process has identified a potential problem with this gene model
NLLIHHGE_00147 2.5e-86 K FR47-like protein
NLLIHHGE_00148 1.1e-121 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
NLLIHHGE_00150 5e-75 osmC O OsmC-like protein
NLLIHHGE_00151 3.7e-174 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLLIHHGE_00152 2e-219 patA 2.6.1.1 E Aminotransferase
NLLIHHGE_00153 2.7e-32
NLLIHHGE_00154 0.0 clpL O associated with various cellular activities
NLLIHHGE_00155 2.2e-156 L hmm pf00665
NLLIHHGE_00156 2.2e-128 L Helix-turn-helix domain
NLLIHHGE_00157 2.6e-217 L Integrase core domain
NLLIHHGE_00158 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_00159 1.2e-81 S ECF transporter, substrate-specific component
NLLIHHGE_00160 8.1e-61 S Domain of unknown function (DUF4430)
NLLIHHGE_00161 6.5e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
NLLIHHGE_00162 5.8e-129 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NLLIHHGE_00163 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
NLLIHHGE_00164 7.1e-133 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NLLIHHGE_00165 4.6e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
NLLIHHGE_00166 1.4e-250 hemL 5.4.3.8 H Aminotransferase class-III
NLLIHHGE_00167 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
NLLIHHGE_00168 5.5e-164 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NLLIHHGE_00169 2.3e-229 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NLLIHHGE_00170 3e-78 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
NLLIHHGE_00171 3.3e-275 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
NLLIHHGE_00172 1.7e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
NLLIHHGE_00173 5.8e-118 cbiQ P Cobalt transport protein
NLLIHHGE_00174 1.9e-52 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NLLIHHGE_00175 7e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
NLLIHHGE_00176 5.7e-124 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NLLIHHGE_00177 2e-146 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
NLLIHHGE_00178 5.3e-259 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NLLIHHGE_00179 2.9e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
NLLIHHGE_00180 2.2e-131 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NLLIHHGE_00181 3e-190 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
NLLIHHGE_00182 2e-135 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NLLIHHGE_00183 2.1e-94 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
NLLIHHGE_00184 1e-110 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
NLLIHHGE_00185 4.3e-206 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NLLIHHGE_00186 2.1e-123 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
NLLIHHGE_00187 1.7e-179 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NLLIHHGE_00188 8e-260 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
NLLIHHGE_00189 1.5e-205 cobD 4.1.1.81 E Aminotransferase class I and II
NLLIHHGE_00190 1.8e-101 cobO 2.5.1.17 S Cobalamin adenosyltransferase
NLLIHHGE_00191 6.6e-156 XK27_04590 S NADPH-dependent FMN reductase
NLLIHHGE_00192 1.5e-77 fld C Flavodoxin
NLLIHHGE_00193 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
NLLIHHGE_00194 6.7e-80 P Cadmium resistance transporter
NLLIHHGE_00195 6.5e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
NLLIHHGE_00196 4.1e-147 3.1.3.48 T Pfam:Y_phosphatase3C
NLLIHHGE_00197 5.5e-56 pduU E BMC
NLLIHHGE_00198 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLLIHHGE_00199 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
NLLIHHGE_00200 6.8e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
NLLIHHGE_00201 7.4e-80 pduO S Haem-degrading
NLLIHHGE_00202 3.7e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
NLLIHHGE_00203 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
NLLIHHGE_00204 6.4e-90 S Putative propanediol utilisation
NLLIHHGE_00205 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
NLLIHHGE_00206 2.2e-42 pduA_4 CQ BMC
NLLIHHGE_00207 1.4e-72 pduK CQ BMC
NLLIHHGE_00208 6.5e-60 pduH S Dehydratase medium subunit
NLLIHHGE_00209 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
NLLIHHGE_00210 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
NLLIHHGE_00211 1.1e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
NLLIHHGE_00212 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
NLLIHHGE_00213 4.6e-134 pduB E BMC
NLLIHHGE_00214 6.2e-42 pduA_4 CQ BMC
NLLIHHGE_00215 4.7e-199 K helix_turn_helix, arabinose operon control protein
NLLIHHGE_00216 2.3e-148 eutJ E Hsp70 protein
NLLIHHGE_00217 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NLLIHHGE_00218 2.1e-163
NLLIHHGE_00219 1.1e-158 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NLLIHHGE_00220 1e-172 S AI-2E family transporter
NLLIHHGE_00221 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
NLLIHHGE_00222 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
NLLIHHGE_00223 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
NLLIHHGE_00224 6.7e-90 GM epimerase
NLLIHHGE_00225 9.8e-155 ypdB V (ABC) transporter
NLLIHHGE_00226 1.9e-242 yhdP S Transporter associated domain
NLLIHHGE_00227 9.9e-85 nrdI F Belongs to the NrdI family
NLLIHHGE_00228 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
NLLIHHGE_00229 2.6e-192 yeaN P Transporter, major facilitator family protein
NLLIHHGE_00230 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NLLIHHGE_00231 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NLLIHHGE_00232 4.2e-40
NLLIHHGE_00233 4.9e-287 lacS G Transporter
NLLIHHGE_00234 4e-09 ltrA S Bacterial low temperature requirement A protein (LtrA)
NLLIHHGE_00235 3.3e-80 uspA T universal stress protein
NLLIHHGE_00236 1.5e-80 K AsnC family
NLLIHHGE_00237 3e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NLLIHHGE_00238 1.6e-98 dedA 3.1.3.1 S SNARE associated Golgi protein
NLLIHHGE_00239 1.2e-180 galR K Transcriptional regulator
NLLIHHGE_00240 1.5e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NLLIHHGE_00241 3.2e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NLLIHHGE_00242 2.8e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NLLIHHGE_00243 1.5e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
NLLIHHGE_00244 6.3e-93 yxkA S Phosphatidylethanolamine-binding protein
NLLIHHGE_00245 9.1e-36
NLLIHHGE_00246 2.6e-52
NLLIHHGE_00247 1.5e-203
NLLIHHGE_00248 3.7e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLLIHHGE_00249 1.8e-136 pnuC H nicotinamide mononucleotide transporter
NLLIHHGE_00250 8.6e-156 ytbE 1.1.1.346 S Aldo keto reductase
NLLIHHGE_00251 1.4e-124 K response regulator
NLLIHHGE_00252 2.5e-183 T PhoQ Sensor
NLLIHHGE_00253 7.5e-135 macB2 V ABC transporter, ATP-binding protein
NLLIHHGE_00254 0.0 ysaB V FtsX-like permease family
NLLIHHGE_00255 1.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NLLIHHGE_00256 9.1e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLLIHHGE_00257 3.6e-54 K helix_turn_helix, mercury resistance
NLLIHHGE_00258 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLLIHHGE_00259 2.4e-196 EGP Major facilitator Superfamily
NLLIHHGE_00260 8.4e-90 ymdB S Macro domain protein
NLLIHHGE_00261 3.3e-104 K Helix-turn-helix XRE-family like proteins
NLLIHHGE_00262 0.0 pepO 3.4.24.71 O Peptidase family M13
NLLIHHGE_00263 4.6e-48
NLLIHHGE_00264 2.6e-236 S Putative metallopeptidase domain
NLLIHHGE_00265 1.2e-203 3.1.3.1 S associated with various cellular activities
NLLIHHGE_00266 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NLLIHHGE_00267 1.4e-65 yeaO S Protein of unknown function, DUF488
NLLIHHGE_00269 2.4e-116 yrkL S Flavodoxin-like fold
NLLIHHGE_00270 3.6e-54
NLLIHHGE_00271 1e-19 S Domain of unknown function (DUF4767)
NLLIHHGE_00272 2.5e-136 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NLLIHHGE_00273 6.3e-50
NLLIHHGE_00277 1.7e-12 K Helix-turn-helix domain
NLLIHHGE_00279 1.7e-204 nrnB S DHHA1 domain
NLLIHHGE_00280 1.9e-214 S Uncharacterized protein conserved in bacteria (DUF2325)
NLLIHHGE_00281 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
NLLIHHGE_00282 1.3e-105 NU mannosyl-glycoprotein
NLLIHHGE_00283 2e-143 S Putative ABC-transporter type IV
NLLIHHGE_00284 4.2e-273 S ABC transporter, ATP-binding protein
NLLIHHGE_00285 2.9e-11
NLLIHHGE_00287 8.1e-08 S Domain of unknown function (DUF296)
NLLIHHGE_00288 2.7e-71 M PFAM NLP P60 protein
NLLIHHGE_00289 9.8e-183 ABC-SBP S ABC transporter
NLLIHHGE_00290 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NLLIHHGE_00291 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
NLLIHHGE_00292 1e-91 P Cadmium resistance transporter
NLLIHHGE_00293 1.2e-55 K Transcriptional regulator, ArsR family
NLLIHHGE_00294 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_00295 2.6e-217 L Integrase core domain
NLLIHHGE_00296 8.4e-111 3.1.21.3 L Type I restriction modification DNA specificity domain
NLLIHHGE_00297 1.1e-08 L restriction endonuclease
NLLIHHGE_00299 6.1e-80 K Putative DNA-binding domain
NLLIHHGE_00300 7e-10 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NLLIHHGE_00301 1e-20 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
NLLIHHGE_00303 9.1e-34 higA K addiction module antidote protein HigA
NLLIHHGE_00304 2.1e-20
NLLIHHGE_00305 0.0 L PLD-like domain
NLLIHHGE_00307 5.6e-180 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NLLIHHGE_00308 5.3e-195 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NLLIHHGE_00309 9.7e-93 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NLLIHHGE_00310 8e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NLLIHHGE_00311 8.8e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NLLIHHGE_00312 1.5e-103 T Ion transport 2 domain protein
NLLIHHGE_00313 0.0 S Bacterial membrane protein YfhO
NLLIHHGE_00314 5e-202 G Transporter, major facilitator family protein
NLLIHHGE_00315 2.4e-109 yvrI K sigma factor activity
NLLIHHGE_00316 8.5e-63 ydiI Q Thioesterase superfamily
NLLIHHGE_00317 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NLLIHHGE_00318 2.5e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NLLIHHGE_00319 2.6e-158 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NLLIHHGE_00320 1.7e-196 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NLLIHHGE_00321 1.2e-31 feoA P FeoA domain
NLLIHHGE_00322 6.5e-145 sufC O FeS assembly ATPase SufC
NLLIHHGE_00323 2.5e-239 sufD O FeS assembly protein SufD
NLLIHHGE_00324 2.3e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NLLIHHGE_00325 1.2e-79 nifU C SUF system FeS assembly protein, NifU family
NLLIHHGE_00326 2.3e-270 sufB O assembly protein SufB
NLLIHHGE_00327 2.8e-57 yitW S Iron-sulfur cluster assembly protein
NLLIHHGE_00328 4.2e-161 hipB K Helix-turn-helix
NLLIHHGE_00329 4.9e-114 nreC K PFAM regulatory protein LuxR
NLLIHHGE_00330 9.2e-39 S Cytochrome B5
NLLIHHGE_00331 5.8e-157 yitU 3.1.3.104 S hydrolase
NLLIHHGE_00332 3.6e-260 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NLLIHHGE_00333 4e-148 f42a O Band 7 protein
NLLIHHGE_00334 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
NLLIHHGE_00335 1.6e-129 lytT K response regulator receiver
NLLIHHGE_00336 1.9e-66 lrgA S LrgA family
NLLIHHGE_00337 2.6e-124 lrgB M LrgB-like family
NLLIHHGE_00338 6.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NLLIHHGE_00339 1.7e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NLLIHHGE_00340 2.3e-187 galR K Periplasmic binding protein-like domain
NLLIHHGE_00341 0.0 rafA 3.2.1.22 G alpha-galactosidase
NLLIHHGE_00342 3.8e-87 S Protein of unknown function (DUF1440)
NLLIHHGE_00343 3.8e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NLLIHHGE_00344 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NLLIHHGE_00345 4.2e-162 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NLLIHHGE_00346 2e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NLLIHHGE_00347 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NLLIHHGE_00348 2.9e-85 ypmB S Protein conserved in bacteria
NLLIHHGE_00349 7.3e-124 dnaD L DnaD domain protein
NLLIHHGE_00350 1.4e-162 EG EamA-like transporter family
NLLIHHGE_00351 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NLLIHHGE_00352 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NLLIHHGE_00353 8.9e-104 ypsA S Belongs to the UPF0398 family
NLLIHHGE_00354 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NLLIHHGE_00355 3.2e-83 F Belongs to the NrdI family
NLLIHHGE_00356 1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NLLIHHGE_00357 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
NLLIHHGE_00358 1.5e-65 esbA S Family of unknown function (DUF5322)
NLLIHHGE_00359 2.2e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NLLIHHGE_00360 3.1e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLLIHHGE_00361 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
NLLIHHGE_00362 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NLLIHHGE_00363 0.0 FbpA K Fibronectin-binding protein
NLLIHHGE_00364 6.4e-162 degV S EDD domain protein, DegV family
NLLIHHGE_00365 7.6e-94
NLLIHHGE_00366 2.3e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NLLIHHGE_00367 8.4e-159 gspA M family 8
NLLIHHGE_00368 3.4e-160 S Alpha beta hydrolase
NLLIHHGE_00369 2.4e-95 K Acetyltransferase (GNAT) domain
NLLIHHGE_00370 8.7e-243 XK27_08635 S UPF0210 protein
NLLIHHGE_00371 2.1e-39 gcvR T Belongs to the UPF0237 family
NLLIHHGE_00372 5.5e-169 1.1.1.346 C Aldo keto reductase
NLLIHHGE_00373 2.7e-95 exuR K Periplasmic binding protein domain
NLLIHHGE_00374 1.4e-220 yjmB G MFS/sugar transport protein
NLLIHHGE_00375 3.6e-226 uxaC 5.3.1.12 G glucuronate isomerase
NLLIHHGE_00376 1.2e-94 S module of peptide synthetase
NLLIHHGE_00378 6.3e-151 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NLLIHHGE_00379 4.3e-126 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NLLIHHGE_00380 1.8e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
NLLIHHGE_00381 9.3e-161 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NLLIHHGE_00382 2.1e-124 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
NLLIHHGE_00383 1.5e-52 kdgR K FCD domain
NLLIHHGE_00384 1.1e-210 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
NLLIHHGE_00385 4.4e-181 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NLLIHHGE_00386 1.2e-214 uxuT G MFS/sugar transport protein
NLLIHHGE_00387 8.1e-218 uxaC 5.3.1.12 G glucuronate isomerase
NLLIHHGE_00388 1.1e-134 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NLLIHHGE_00389 2.3e-129 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NLLIHHGE_00390 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_00391 2.6e-217 L Integrase core domain
NLLIHHGE_00392 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NLLIHHGE_00393 5.2e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NLLIHHGE_00394 5.2e-203 coiA 3.6.4.12 S Competence protein
NLLIHHGE_00395 2.6e-266 pipD E Dipeptidase
NLLIHHGE_00396 4.7e-114 yjbH Q Thioredoxin
NLLIHHGE_00397 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
NLLIHHGE_00398 6e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NLLIHHGE_00399 4.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NLLIHHGE_00401 9.5e-194 nss M transferase activity, transferring glycosyl groups
NLLIHHGE_00402 4e-103 cpsJ S glycosyl transferase family 2
NLLIHHGE_00403 1.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
NLLIHHGE_00404 3.1e-289 M transferase activity, transferring glycosyl groups
NLLIHHGE_00405 1.5e-288 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
NLLIHHGE_00406 7e-164 asp3 S Accessory Sec secretory system ASP3
NLLIHHGE_00407 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLLIHHGE_00408 6.8e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
NLLIHHGE_00409 3.9e-259 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
NLLIHHGE_00411 6.7e-70 M family 8
NLLIHHGE_00412 5e-202 M family 8
NLLIHHGE_00413 1.4e-284 GT2,GT4 M family 8
NLLIHHGE_00415 4.5e-165 L Transposase
NLLIHHGE_00417 8.8e-15
NLLIHHGE_00418 5.7e-242 glpT G Major Facilitator Superfamily
NLLIHHGE_00419 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NLLIHHGE_00421 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NLLIHHGE_00422 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NLLIHHGE_00423 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLLIHHGE_00424 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NLLIHHGE_00425 7.1e-248 yifK E Amino acid permease
NLLIHHGE_00426 5.6e-294 clcA P chloride
NLLIHHGE_00427 1.8e-34 secG U Preprotein translocase
NLLIHHGE_00428 8.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
NLLIHHGE_00429 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NLLIHHGE_00430 4.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NLLIHHGE_00431 3.7e-105 yxjI
NLLIHHGE_00432 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NLLIHHGE_00433 8.4e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NLLIHHGE_00434 2.2e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NLLIHHGE_00435 3.9e-87 K Acetyltransferase (GNAT) domain
NLLIHHGE_00436 4.4e-76 S PAS domain
NLLIHHGE_00437 1.7e-101 dnaQ 2.7.7.7 L DNA polymerase III
NLLIHHGE_00438 1.6e-168 murB 1.3.1.98 M Cell wall formation
NLLIHHGE_00439 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLLIHHGE_00440 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NLLIHHGE_00441 3.7e-249 fucP G Major Facilitator Superfamily
NLLIHHGE_00442 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NLLIHHGE_00443 2e-126 ybbR S YbbR-like protein
NLLIHHGE_00444 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NLLIHHGE_00445 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NLLIHHGE_00446 8.7e-53
NLLIHHGE_00447 0.0 oatA I Acyltransferase
NLLIHHGE_00448 2.3e-81 K Transcriptional regulator
NLLIHHGE_00449 7e-147 XK27_02985 S Cof-like hydrolase
NLLIHHGE_00450 1.8e-78 lytE M Lysin motif
NLLIHHGE_00452 3e-133 K response regulator
NLLIHHGE_00453 2.4e-273 yclK 2.7.13.3 T Histidine kinase
NLLIHHGE_00454 3.4e-155 glcU U sugar transport
NLLIHHGE_00455 4e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
NLLIHHGE_00456 1.3e-262 pgi 5.3.1.9 G Belongs to the GPI family
NLLIHHGE_00457 2.7e-26
NLLIHHGE_00458 2.7e-119 L Transposase
NLLIHHGE_00459 4e-170 whiA K May be required for sporulation
NLLIHHGE_00460 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NLLIHHGE_00461 1.1e-161 rapZ S Displays ATPase and GTPase activities
NLLIHHGE_00462 7.1e-245 steT E amino acid
NLLIHHGE_00463 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NLLIHHGE_00464 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NLLIHHGE_00465 1.5e-13
NLLIHHGE_00466 6.6e-116 yfbR S HD containing hydrolase-like enzyme
NLLIHHGE_00467 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NLLIHHGE_00468 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
NLLIHHGE_00469 1.1e-161 aatB ET PFAM extracellular solute-binding protein, family 3
NLLIHHGE_00470 1e-215 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NLLIHHGE_00471 1e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NLLIHHGE_00472 4e-158 lutA C Cysteine-rich domain
NLLIHHGE_00473 5.8e-288 lutB C 4Fe-4S dicluster domain
NLLIHHGE_00474 3.9e-136 yrjD S LUD domain
NLLIHHGE_00475 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NLLIHHGE_00476 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NLLIHHGE_00477 1.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NLLIHHGE_00478 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NLLIHHGE_00479 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NLLIHHGE_00480 3.1e-32 KT PspC domain protein
NLLIHHGE_00481 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NLLIHHGE_00482 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NLLIHHGE_00483 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NLLIHHGE_00484 6.5e-114 comFC S Competence protein
NLLIHHGE_00485 1.3e-254 comFA L Helicase C-terminal domain protein
NLLIHHGE_00486 2.3e-108 yvyE 3.4.13.9 S YigZ family
NLLIHHGE_00487 3e-39 C nitroreductase
NLLIHHGE_00488 3.7e-236 EGP Major facilitator Superfamily
NLLIHHGE_00489 3.3e-68 rmaI K Transcriptional regulator
NLLIHHGE_00490 7.8e-39
NLLIHHGE_00491 0.0 ydaO E amino acid
NLLIHHGE_00492 1.3e-304 ybeC E amino acid
NLLIHHGE_00493 1.8e-84 S Aminoacyl-tRNA editing domain
NLLIHHGE_00494 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NLLIHHGE_00495 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NLLIHHGE_00497 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NLLIHHGE_00498 0.0 uup S ABC transporter, ATP-binding protein
NLLIHHGE_00499 3.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLLIHHGE_00500 8.5e-226 mtnE 2.6.1.83 E Aminotransferase
NLLIHHGE_00501 4.6e-143 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NLLIHHGE_00502 3.8e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NLLIHHGE_00503 2.1e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NLLIHHGE_00504 3.6e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NLLIHHGE_00505 4.2e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NLLIHHGE_00506 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NLLIHHGE_00507 2.3e-125 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NLLIHHGE_00508 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NLLIHHGE_00509 3.3e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NLLIHHGE_00510 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NLLIHHGE_00511 6.3e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NLLIHHGE_00512 4.8e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
NLLIHHGE_00513 6.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NLLIHHGE_00514 5.9e-58 yabA L Involved in initiation control of chromosome replication
NLLIHHGE_00515 8.2e-185 holB 2.7.7.7 L DNA polymerase III
NLLIHHGE_00516 7.6e-52 yaaQ S Cyclic-di-AMP receptor
NLLIHHGE_00517 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NLLIHHGE_00518 9.7e-39 S Protein of unknown function (DUF2508)
NLLIHHGE_00519 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NLLIHHGE_00520 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NLLIHHGE_00521 8.6e-302 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLLIHHGE_00522 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NLLIHHGE_00523 3.4e-35 nrdH O Glutaredoxin
NLLIHHGE_00524 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLLIHHGE_00525 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NLLIHHGE_00526 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NLLIHHGE_00527 3.9e-131 S Putative adhesin
NLLIHHGE_00528 1.1e-70 XK27_06920 S Protein of unknown function (DUF1700)
NLLIHHGE_00529 1.2e-55 K transcriptional regulator PadR family
NLLIHHGE_00530 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NLLIHHGE_00532 7.7e-48
NLLIHHGE_00533 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NLLIHHGE_00534 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NLLIHHGE_00535 3.1e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NLLIHHGE_00536 4e-245 M Glycosyl transferase family group 2
NLLIHHGE_00538 1e-226 aadAT EK Aminotransferase, class I
NLLIHHGE_00539 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NLLIHHGE_00540 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NLLIHHGE_00541 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
NLLIHHGE_00542 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NLLIHHGE_00543 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLLIHHGE_00544 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLLIHHGE_00545 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NLLIHHGE_00546 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLLIHHGE_00547 1.7e-207 yacL S domain protein
NLLIHHGE_00548 2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NLLIHHGE_00549 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NLLIHHGE_00550 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
NLLIHHGE_00551 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NLLIHHGE_00552 6.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
NLLIHHGE_00553 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NLLIHHGE_00554 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLLIHHGE_00555 1.1e-119 tcyB E ABC transporter
NLLIHHGE_00556 7.7e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NLLIHHGE_00557 1.2e-168 I alpha/beta hydrolase fold
NLLIHHGE_00558 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLLIHHGE_00559 0.0 S Bacterial membrane protein, YfhO
NLLIHHGE_00560 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NLLIHHGE_00561 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NLLIHHGE_00563 7.3e-85 ydcK S Belongs to the SprT family
NLLIHHGE_00564 0.0 yhgF K Tex-like protein N-terminal domain protein
NLLIHHGE_00565 3.3e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NLLIHHGE_00566 1.2e-282 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NLLIHHGE_00567 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
NLLIHHGE_00568 6.9e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NLLIHHGE_00569 1e-298 aspT P Predicted Permease Membrane Region
NLLIHHGE_00570 2.6e-250 EGP Major facilitator Superfamily
NLLIHHGE_00571 1.4e-110
NLLIHHGE_00574 9.1e-150 yjjH S Calcineurin-like phosphoesterase
NLLIHHGE_00575 1.3e-263 dtpT U amino acid peptide transporter
NLLIHHGE_00576 2.8e-19
NLLIHHGE_00580 3.4e-178 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NLLIHHGE_00581 2.2e-159 rrmA 2.1.1.187 H Methyltransferase
NLLIHHGE_00582 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NLLIHHGE_00583 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NLLIHHGE_00584 1.2e-10 S Protein of unknown function (DUF4044)
NLLIHHGE_00585 1.7e-57
NLLIHHGE_00586 3.1e-77 mraZ K Belongs to the MraZ family
NLLIHHGE_00587 6.8e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NLLIHHGE_00588 1.5e-56 ftsL D Cell division protein FtsL
NLLIHHGE_00589 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NLLIHHGE_00590 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NLLIHHGE_00591 2.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NLLIHHGE_00592 4.3e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NLLIHHGE_00593 1.6e-149 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NLLIHHGE_00594 9.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NLLIHHGE_00595 1.5e-225 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NLLIHHGE_00596 1.2e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NLLIHHGE_00597 8.3e-41 yggT S YGGT family
NLLIHHGE_00598 1.9e-144 ylmH S S4 domain protein
NLLIHHGE_00599 1.9e-42 divIVA D DivIVA domain protein
NLLIHHGE_00600 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NLLIHHGE_00601 4.2e-32 cspA K Cold shock protein
NLLIHHGE_00602 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NLLIHHGE_00604 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NLLIHHGE_00605 3.5e-216 iscS 2.8.1.7 E Aminotransferase class V
NLLIHHGE_00606 7.5e-58 XK27_04120 S Putative amino acid metabolism
NLLIHHGE_00607 1.6e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NLLIHHGE_00608 3.7e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NLLIHHGE_00609 9e-119 S Repeat protein
NLLIHHGE_00610 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NLLIHHGE_00611 8.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLLIHHGE_00612 3.8e-280 UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_00613 1.3e-156 UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_00614 5.2e-168 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NLLIHHGE_00615 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NLLIHHGE_00616 1.4e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NLLIHHGE_00617 6.7e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NLLIHHGE_00618 4.2e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NLLIHHGE_00619 2.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NLLIHHGE_00620 7.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NLLIHHGE_00621 1.6e-219 patA 2.6.1.1 E Aminotransferase
NLLIHHGE_00622 3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NLLIHHGE_00623 1.4e-83 KT Putative sugar diacid recognition
NLLIHHGE_00624 7.6e-220 EG GntP family permease
NLLIHHGE_00625 1.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NLLIHHGE_00626 2.2e-57
NLLIHHGE_00628 9.1e-137 mltD CBM50 M NlpC P60 family protein
NLLIHHGE_00629 5.7e-29
NLLIHHGE_00630 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
NLLIHHGE_00631 9.8e-32 ykzG S Belongs to the UPF0356 family
NLLIHHGE_00632 4.7e-82
NLLIHHGE_00633 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NLLIHHGE_00634 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NLLIHHGE_00635 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NLLIHHGE_00636 8.7e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NLLIHHGE_00637 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
NLLIHHGE_00638 1.4e-47 yktA S Belongs to the UPF0223 family
NLLIHHGE_00639 4.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NLLIHHGE_00640 0.0 typA T GTP-binding protein TypA
NLLIHHGE_00641 1.2e-222 ftsW D Belongs to the SEDS family
NLLIHHGE_00642 6.7e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NLLIHHGE_00643 1.4e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NLLIHHGE_00644 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NLLIHHGE_00645 2.3e-198 ylbL T Belongs to the peptidase S16 family
NLLIHHGE_00646 6.9e-81 comEA L Competence protein ComEA
NLLIHHGE_00647 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
NLLIHHGE_00648 0.0 comEC S Competence protein ComEC
NLLIHHGE_00649 7.6e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
NLLIHHGE_00650 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
NLLIHHGE_00651 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NLLIHHGE_00652 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLLIHHGE_00653 1.3e-162 S Tetratricopeptide repeat
NLLIHHGE_00654 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NLLIHHGE_00655 1.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NLLIHHGE_00656 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NLLIHHGE_00657 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
NLLIHHGE_00658 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NLLIHHGE_00659 4.9e-08
NLLIHHGE_00660 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NLLIHHGE_00661 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NLLIHHGE_00662 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NLLIHHGE_00663 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLIHHGE_00664 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NLLIHHGE_00665 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NLLIHHGE_00666 2.5e-88
NLLIHHGE_00667 3.5e-133 L Belongs to the 'phage' integrase family
NLLIHHGE_00668 3.2e-12 xre K sequence-specific DNA binding
NLLIHHGE_00669 2.2e-14
NLLIHHGE_00670 1.5e-43 S Phage regulatory protein Rha (Phage_pRha)
NLLIHHGE_00673 6.6e-08
NLLIHHGE_00677 3.3e-13 L DnaD domain protein
NLLIHHGE_00679 3.8e-69
NLLIHHGE_00680 3e-07
NLLIHHGE_00681 1.4e-164 D NLP P60 protein
NLLIHHGE_00682 2.1e-191 D NLP P60 protein
NLLIHHGE_00684 3.1e-57
NLLIHHGE_00686 1.1e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLLIHHGE_00687 1.2e-211 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NLLIHHGE_00688 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NLLIHHGE_00689 1.3e-35 ynzC S UPF0291 protein
NLLIHHGE_00690 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
NLLIHHGE_00691 1.6e-117 plsC 2.3.1.51 I Acyltransferase
NLLIHHGE_00692 3e-139 yabB 2.1.1.223 L Methyltransferase small domain
NLLIHHGE_00693 2.1e-48 yazA L GIY-YIG catalytic domain protein
NLLIHHGE_00694 2e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLLIHHGE_00695 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
NLLIHHGE_00696 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NLLIHHGE_00697 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NLLIHHGE_00698 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NLLIHHGE_00699 8.4e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NLLIHHGE_00700 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
NLLIHHGE_00701 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NLLIHHGE_00702 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NLLIHHGE_00703 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NLLIHHGE_00704 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NLLIHHGE_00705 4.6e-211 nusA K Participates in both transcription termination and antitermination
NLLIHHGE_00706 1e-44 ylxR K Protein of unknown function (DUF448)
NLLIHHGE_00707 3.8e-48 ylxQ J ribosomal protein
NLLIHHGE_00708 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NLLIHHGE_00709 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NLLIHHGE_00710 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NLLIHHGE_00711 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NLLIHHGE_00712 7.6e-64
NLLIHHGE_00713 1.8e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NLLIHHGE_00714 1.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NLLIHHGE_00715 0.0 dnaK O Heat shock 70 kDa protein
NLLIHHGE_00716 7.3e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NLLIHHGE_00717 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NLLIHHGE_00718 1.1e-69 3.6.4.12 L Belongs to the 'phage' integrase family
NLLIHHGE_00719 1.7e-27 3.6.4.12 L Belongs to the 'phage' integrase family
NLLIHHGE_00720 2.6e-217 L Integrase core domain
NLLIHHGE_00721 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_00722 2.2e-156 L hmm pf00665
NLLIHHGE_00723 2.2e-128 L Helix-turn-helix domain
NLLIHHGE_00725 3.7e-105 wecD3 K PFAM GCN5-related N-acetyltransferase
NLLIHHGE_00726 2.6e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NLLIHHGE_00727 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NLLIHHGE_00728 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NLLIHHGE_00729 3.5e-174 malR K Transcriptional regulator, LacI family
NLLIHHGE_00730 3.2e-209 phbA 2.3.1.9 I Belongs to the thiolase family
NLLIHHGE_00731 6.9e-256 malT G Major Facilitator
NLLIHHGE_00732 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NLLIHHGE_00733 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NLLIHHGE_00734 4.2e-70
NLLIHHGE_00735 1.3e-87 2.7.6.5 T Region found in RelA / SpoT proteins
NLLIHHGE_00736 7.6e-115 K response regulator
NLLIHHGE_00737 1e-221 sptS 2.7.13.3 T Histidine kinase
NLLIHHGE_00738 4.4e-206 yfeO P Voltage gated chloride channel
NLLIHHGE_00739 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NLLIHHGE_00740 5e-136 puuD S peptidase C26
NLLIHHGE_00741 2.3e-167 yvgN C Aldo keto reductase
NLLIHHGE_00742 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NLLIHHGE_00743 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
NLLIHHGE_00744 3.5e-260 nox C NADH oxidase
NLLIHHGE_00745 8.4e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLLIHHGE_00746 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NLLIHHGE_00747 1.4e-86
NLLIHHGE_00748 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NLLIHHGE_00750 9e-113 K Transcriptional regulator, TetR family
NLLIHHGE_00751 1e-69
NLLIHHGE_00752 4.8e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NLLIHHGE_00753 3.9e-268 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NLLIHHGE_00754 3.3e-288 M domain protein
NLLIHHGE_00755 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
NLLIHHGE_00756 1.5e-266 G Major Facilitator
NLLIHHGE_00757 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NLLIHHGE_00758 4.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NLLIHHGE_00759 3.6e-260 G Major Facilitator
NLLIHHGE_00760 7.1e-181 K Transcriptional regulator, LacI family
NLLIHHGE_00761 4.8e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLLIHHGE_00763 4.9e-102 nqr 1.5.1.36 S reductase
NLLIHHGE_00764 1.9e-199 XK27_09615 S reductase
NLLIHHGE_00765 1.2e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NLLIHHGE_00766 2.2e-128 L Helix-turn-helix domain
NLLIHHGE_00767 2.2e-156 L hmm pf00665
NLLIHHGE_00768 8e-120 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
NLLIHHGE_00769 1.9e-159 mleP3 S Membrane transport protein
NLLIHHGE_00770 2.7e-224 4.4.1.8 E Aminotransferase, class I
NLLIHHGE_00771 4.4e-99 M Protein of unknown function (DUF3737)
NLLIHHGE_00772 8.6e-56 yphJ 4.1.1.44 S decarboxylase
NLLIHHGE_00773 2.3e-164 S Oxidoreductase, aldo keto reductase family protein
NLLIHHGE_00774 4.2e-86 C Flavodoxin
NLLIHHGE_00775 9.4e-17
NLLIHHGE_00776 4.8e-149 K Transcriptional regulator
NLLIHHGE_00777 7e-87 lacA S transferase hexapeptide repeat
NLLIHHGE_00778 3.3e-135 S Hydrolases of the alpha beta superfamily
NLLIHHGE_00779 1.5e-150 S Alpha beta hydrolase
NLLIHHGE_00780 7.7e-171 L transposase, IS605 OrfB family
NLLIHHGE_00781 2.7e-94 padC Q Phenolic acid decarboxylase
NLLIHHGE_00782 5.9e-94 padR K Virulence activator alpha C-term
NLLIHHGE_00783 1.1e-65 GM NAD(P)H-binding
NLLIHHGE_00784 4.3e-154 ypuA S Protein of unknown function (DUF1002)
NLLIHHGE_00785 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
NLLIHHGE_00786 9.3e-137 K Transcriptional regulator
NLLIHHGE_00787 2.9e-162 akr5f 1.1.1.346 S reductase
NLLIHHGE_00788 1.8e-104 K Transcriptional regulator C-terminal region
NLLIHHGE_00789 6.2e-189 S membrane
NLLIHHGE_00790 1.2e-112 GM NAD(P)H-binding
NLLIHHGE_00791 1.1e-64 yneR
NLLIHHGE_00792 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NLLIHHGE_00793 2.4e-142 T EAL domain
NLLIHHGE_00794 3.4e-247 pgaC GT2 M Glycosyl transferase
NLLIHHGE_00795 8e-85
NLLIHHGE_00796 7.1e-201 2.7.7.65 T GGDEF domain
NLLIHHGE_00797 1.8e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NLLIHHGE_00798 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NLLIHHGE_00799 1.4e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
NLLIHHGE_00800 1.5e-92 folT S ECF transporter, substrate-specific component
NLLIHHGE_00801 0.0 pepN 3.4.11.2 E aminopeptidase
NLLIHHGE_00802 1.5e-112 ylbE GM NAD dependent epimerase dehydratase family protein
NLLIHHGE_00803 1.5e-255 pepC 3.4.22.40 E aminopeptidase
NLLIHHGE_00804 1e-210 EGP Major facilitator Superfamily
NLLIHHGE_00805 6.5e-235
NLLIHHGE_00806 6.2e-84 K Transcriptional regulator, HxlR family
NLLIHHGE_00807 9.7e-109 XK27_02070 S Nitroreductase family
NLLIHHGE_00808 2.5e-52 hxlR K Transcriptional regulator, HxlR family
NLLIHHGE_00809 7.8e-120 GM NmrA-like family
NLLIHHGE_00810 1.6e-76 elaA S Gnat family
NLLIHHGE_00811 2.4e-39 S Cytochrome B5
NLLIHHGE_00812 5.4e-09 S Cytochrome B5
NLLIHHGE_00813 3.5e-41 S Cytochrome B5
NLLIHHGE_00814 2.3e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
NLLIHHGE_00816 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NLLIHHGE_00817 2.4e-240 E amino acid
NLLIHHGE_00818 6.4e-262 npp S type I phosphodiesterase nucleotide pyrophosphatase
NLLIHHGE_00819 1.2e-227 yxiO S Vacuole effluxer Atg22 like
NLLIHHGE_00821 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NLLIHHGE_00822 5.2e-34
NLLIHHGE_00823 3.9e-290 mntH P H( )-stimulated, divalent metal cation uptake system
NLLIHHGE_00824 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
NLLIHHGE_00825 2.6e-86 ygfC K transcriptional regulator (TetR family)
NLLIHHGE_00826 6.8e-174 hrtB V ABC transporter permease
NLLIHHGE_00827 1.2e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NLLIHHGE_00828 5.6e-175 yhcA V ABC transporter, ATP-binding protein
NLLIHHGE_00829 3.4e-159 yhcA V ABC transporter, ATP-binding protein
NLLIHHGE_00830 1e-37
NLLIHHGE_00831 4.1e-50 czrA K Transcriptional regulator, ArsR family
NLLIHHGE_00832 3.3e-239 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLLIHHGE_00833 2.5e-167 scrR K Transcriptional regulator, LacI family
NLLIHHGE_00834 1e-24
NLLIHHGE_00835 5.5e-107
NLLIHHGE_00836 9e-207 yttB EGP Major facilitator Superfamily
NLLIHHGE_00837 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
NLLIHHGE_00838 3.5e-88
NLLIHHGE_00839 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
NLLIHHGE_00840 1.2e-263 S Putative peptidoglycan binding domain
NLLIHHGE_00841 1.4e-124 yciB M ErfK YbiS YcfS YnhG
NLLIHHGE_00843 4.6e-100
NLLIHHGE_00844 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLLIHHGE_00845 7e-126 S Alpha beta hydrolase
NLLIHHGE_00846 7.6e-208 gldA 1.1.1.6 C dehydrogenase
NLLIHHGE_00847 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NLLIHHGE_00848 1.3e-41
NLLIHHGE_00849 5.5e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
NLLIHHGE_00850 5.3e-284 S C4-dicarboxylate anaerobic carrier
NLLIHHGE_00851 2.7e-250 nhaC C Na H antiporter NhaC
NLLIHHGE_00852 3.6e-241 pbuX F xanthine permease
NLLIHHGE_00853 7e-283 pipD E Dipeptidase
NLLIHHGE_00854 9.7e-169 corA P CorA-like Mg2+ transporter protein
NLLIHHGE_00855 2e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NLLIHHGE_00856 2.3e-131 terC P membrane
NLLIHHGE_00857 2.1e-54 trxA O Belongs to the thioredoxin family
NLLIHHGE_00858 2.7e-236 mepA V MATE efflux family protein
NLLIHHGE_00859 1.1e-92 M domain protein
NLLIHHGE_00860 3.1e-147 tesE Q hydratase
NLLIHHGE_00861 8.1e-243 codA 3.5.4.1 F cytosine deaminase
NLLIHHGE_00862 8.9e-251 U Belongs to the purine-cytosine permease (2.A.39) family
NLLIHHGE_00863 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
NLLIHHGE_00864 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NLLIHHGE_00865 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NLLIHHGE_00867 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLIHHGE_00868 3e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
NLLIHHGE_00869 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NLLIHHGE_00870 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NLLIHHGE_00871 9e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
NLLIHHGE_00872 0.0 sprD D Domain of Unknown Function (DUF1542)
NLLIHHGE_00873 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NLLIHHGE_00874 3.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NLLIHHGE_00875 1.5e-158 htpX O Belongs to the peptidase M48B family
NLLIHHGE_00876 7e-93 lemA S LemA family
NLLIHHGE_00877 5.2e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLLIHHGE_00878 5.4e-121 pgm3 G Belongs to the phosphoglycerate mutase family
NLLIHHGE_00879 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NLLIHHGE_00880 1.2e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLLIHHGE_00881 1.9e-160 3.2.1.55 GH51 G Right handed beta helix region
NLLIHHGE_00882 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NLLIHHGE_00883 5.1e-125 srtA 3.4.22.70 M sortase family
NLLIHHGE_00884 5.7e-166 S Alpha/beta hydrolase of unknown function (DUF915)
NLLIHHGE_00885 1.1e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NLLIHHGE_00886 4.6e-41 rpmE2 J Ribosomal protein L31
NLLIHHGE_00887 1.4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLLIHHGE_00888 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NLLIHHGE_00889 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NLLIHHGE_00890 2.7e-67 ywiB S Domain of unknown function (DUF1934)
NLLIHHGE_00891 5.1e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NLLIHHGE_00892 5.9e-271 ywfO S HD domain protein
NLLIHHGE_00893 1.9e-147 yxeH S hydrolase
NLLIHHGE_00894 1.7e-203 rarA L recombination factor protein RarA
NLLIHHGE_00895 4.3e-50
NLLIHHGE_00896 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NLLIHHGE_00897 1.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NLLIHHGE_00898 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NLLIHHGE_00899 1.6e-127 znuB U ABC 3 transport family
NLLIHHGE_00900 2.2e-122 fhuC P ABC transporter
NLLIHHGE_00901 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
NLLIHHGE_00902 9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NLLIHHGE_00903 6.8e-37 veg S Biofilm formation stimulator VEG
NLLIHHGE_00904 4e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NLLIHHGE_00905 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NLLIHHGE_00906 2.9e-156 tatD L hydrolase, TatD family
NLLIHHGE_00907 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NLLIHHGE_00908 4e-161 yunF F Protein of unknown function DUF72
NLLIHHGE_00910 1.1e-119 cobB K SIR2 family
NLLIHHGE_00911 4.1e-178
NLLIHHGE_00912 2.6e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NLLIHHGE_00913 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NLLIHHGE_00914 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLLIHHGE_00915 5.5e-183 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NLLIHHGE_00916 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
NLLIHHGE_00917 0.0 helD 3.6.4.12 L DNA helicase
NLLIHHGE_00918 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NLLIHHGE_00920 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NLLIHHGE_00921 1.8e-265 yfnA E amino acid
NLLIHHGE_00922 8.4e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NLLIHHGE_00923 4.3e-43 1.3.5.4 S FMN binding
NLLIHHGE_00924 7.1e-220 norA EGP Major facilitator Superfamily
NLLIHHGE_00925 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NLLIHHGE_00926 2.6e-42 S Sugar efflux transporter for intercellular exchange
NLLIHHGE_00927 4e-156 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NLLIHHGE_00928 9.5e-122 scrR3 K Transcriptional regulator, LacI family
NLLIHHGE_00929 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
NLLIHHGE_00930 4.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NLLIHHGE_00931 2.2e-101 metI P ABC transporter permease
NLLIHHGE_00932 1.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NLLIHHGE_00933 2.1e-252 clcA P chloride
NLLIHHGE_00934 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NLLIHHGE_00935 1.6e-98 proW P ABC transporter, permease protein
NLLIHHGE_00936 7.9e-140 proV E ABC transporter, ATP-binding protein
NLLIHHGE_00937 8.2e-109 proWZ P ABC transporter permease
NLLIHHGE_00938 2.3e-159 proX M ABC transporter, substrate-binding protein, QAT family
NLLIHHGE_00939 1.8e-75 K Transcriptional regulator
NLLIHHGE_00940 7.9e-157 1.6.5.2 GM NAD(P)H-binding
NLLIHHGE_00942 1.4e-212 5.4.2.7 G Metalloenzyme superfamily
NLLIHHGE_00943 0.0 cadA P P-type ATPase
NLLIHHGE_00944 2.2e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NLLIHHGE_00945 8.3e-128
NLLIHHGE_00946 1.8e-53 S Sugar efflux transporter for intercellular exchange
NLLIHHGE_00947 8.8e-243 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
NLLIHHGE_00949 0.0 L Helicase C-terminal domain protein
NLLIHHGE_00950 1e-79 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
NLLIHHGE_00951 4.2e-175 S Aldo keto reductase
NLLIHHGE_00952 0.0 rafA 3.2.1.22 G alpha-galactosidase
NLLIHHGE_00953 5.4e-86 S Membrane
NLLIHHGE_00954 9.7e-144 K helix_turn_helix, arabinose operon control protein
NLLIHHGE_00956 9.4e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NLLIHHGE_00957 5.9e-62 psiE S Phosphate-starvation-inducible E
NLLIHHGE_00958 2.5e-100 ydeN S Serine hydrolase
NLLIHHGE_00960 1.6e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NLLIHHGE_00961 2.1e-255 nhaC C Na H antiporter NhaC
NLLIHHGE_00962 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
NLLIHHGE_00963 2.2e-114 ywnB S NAD(P)H-binding
NLLIHHGE_00964 2.9e-37
NLLIHHGE_00965 7.9e-129 IQ Dehydrogenase reductase
NLLIHHGE_00966 3.7e-57
NLLIHHGE_00967 1.6e-53 L Transposase
NLLIHHGE_00968 9e-37 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NLLIHHGE_00969 9.4e-39 trxA O Belongs to the thioredoxin family
NLLIHHGE_00971 1e-95 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NLLIHHGE_00972 1.2e-139 trxB 1.8.1.9 O Glucose inhibited division protein A
NLLIHHGE_00973 3.7e-24 CO cell redox homeostasis
NLLIHHGE_00974 1.4e-70 M1-798 K Rhodanese Homology Domain
NLLIHHGE_00975 6.6e-47 L Transposase IS66 family
NLLIHHGE_00976 0.0 fhaB M Rib/alpha-like repeat
NLLIHHGE_00977 3.8e-64 infB UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_00978 1.5e-57 infB UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_00999 9.5e-155 KT YcbB domain
NLLIHHGE_01000 5.8e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NLLIHHGE_01001 5.6e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
NLLIHHGE_01002 4.3e-161 EG EamA-like transporter family
NLLIHHGE_01003 8.5e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NLLIHHGE_01004 3.3e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NLLIHHGE_01005 2.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NLLIHHGE_01006 0.0 copA 3.6.3.54 P P-type ATPase
NLLIHHGE_01007 3e-89
NLLIHHGE_01009 3.6e-57
NLLIHHGE_01010 2.6e-254 yjcE P Sodium proton antiporter
NLLIHHGE_01012 7.6e-91
NLLIHHGE_01013 0.0 M domain protein
NLLIHHGE_01014 7.7e-34
NLLIHHGE_01015 3.9e-195 ampC V Beta-lactamase
NLLIHHGE_01016 5.9e-238 arcA 3.5.3.6 E Arginine
NLLIHHGE_01017 2.7e-79 argR K Regulates arginine biosynthesis genes
NLLIHHGE_01018 9.8e-261 E Arginine ornithine antiporter
NLLIHHGE_01019 1.2e-221 arcD U Amino acid permease
NLLIHHGE_01020 4.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
NLLIHHGE_01021 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
NLLIHHGE_01022 6e-108 tdk 2.7.1.21 F thymidine kinase
NLLIHHGE_01023 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NLLIHHGE_01024 1e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NLLIHHGE_01025 1.6e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NLLIHHGE_01026 2.5e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NLLIHHGE_01027 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NLLIHHGE_01028 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLLIHHGE_01029 4.4e-192 yibE S overlaps another CDS with the same product name
NLLIHHGE_01030 2.2e-129 yibF S overlaps another CDS with the same product name
NLLIHHGE_01031 5.9e-233 pyrP F Permease
NLLIHHGE_01032 7.6e-121 atpB C it plays a direct role in the translocation of protons across the membrane
NLLIHHGE_01033 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLLIHHGE_01034 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NLLIHHGE_01035 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NLLIHHGE_01036 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NLLIHHGE_01037 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NLLIHHGE_01038 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NLLIHHGE_01039 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NLLIHHGE_01040 1.3e-33 ywzB S Protein of unknown function (DUF1146)
NLLIHHGE_01041 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NLLIHHGE_01042 1.9e-178 mbl D Cell shape determining protein MreB Mrl
NLLIHHGE_01043 1e-31 S Protein of unknown function (DUF2969)
NLLIHHGE_01044 1.1e-220 rodA D Belongs to the SEDS family
NLLIHHGE_01045 3e-47 gcvH E glycine cleavage
NLLIHHGE_01046 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NLLIHHGE_01047 7.9e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NLLIHHGE_01048 3.5e-217 lacY G Oligosaccharide H symporter
NLLIHHGE_01049 1.3e-168 abf G Belongs to the glycosyl hydrolase 43 family
NLLIHHGE_01050 2.5e-145 K transcriptional regulator, ArsR family
NLLIHHGE_01051 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NLLIHHGE_01052 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
NLLIHHGE_01053 4.9e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NLLIHHGE_01054 6.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NLLIHHGE_01055 1.3e-99 maa 2.3.1.79 S Maltose O-acetyltransferase
NLLIHHGE_01056 6e-157 ytbE 1.1.1.346 S Aldo keto reductase
NLLIHHGE_01057 2.2e-207 araR K Transcriptional regulator
NLLIHHGE_01058 4.3e-83 usp6 T universal stress protein
NLLIHHGE_01059 4.4e-46
NLLIHHGE_01060 3.4e-244 rarA L recombination factor protein RarA
NLLIHHGE_01061 6e-85 yueI S Protein of unknown function (DUF1694)
NLLIHHGE_01062 1.5e-21
NLLIHHGE_01063 8.1e-75 4.4.1.5 E Glyoxalase
NLLIHHGE_01064 2.5e-138 S Membrane
NLLIHHGE_01065 2.7e-140 S Belongs to the UPF0246 family
NLLIHHGE_01066 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NLLIHHGE_01067 4.4e-263 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NLLIHHGE_01068 1.3e-235 pbuG S permease
NLLIHHGE_01070 2.7e-119 L Transposase
NLLIHHGE_01071 1e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NLLIHHGE_01072 4.3e-286 gadC E amino acid
NLLIHHGE_01073 3e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
NLLIHHGE_01074 1.7e-290 gadC E amino acid
NLLIHHGE_01075 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NLLIHHGE_01076 1.7e-251 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NLLIHHGE_01077 3.5e-216 iscS2 2.8.1.7 E Aminotransferase class V
NLLIHHGE_01078 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NLLIHHGE_01079 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NLLIHHGE_01080 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
NLLIHHGE_01081 4.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NLLIHHGE_01082 2e-308 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NLLIHHGE_01083 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NLLIHHGE_01084 9e-231 ndh 1.6.99.3 C NADH dehydrogenase
NLLIHHGE_01085 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLLIHHGE_01086 6.8e-121 radC L DNA repair protein
NLLIHHGE_01087 1.7e-179 mreB D cell shape determining protein MreB
NLLIHHGE_01088 5.9e-152 mreC M Involved in formation and maintenance of cell shape
NLLIHHGE_01089 8.7e-93 mreD M rod shape-determining protein MreD
NLLIHHGE_01090 3.2e-102 glnP P ABC transporter permease
NLLIHHGE_01091 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLLIHHGE_01092 2.6e-160 aatB ET ABC transporter substrate-binding protein
NLLIHHGE_01093 7.8e-230 ymfF S Peptidase M16 inactive domain protein
NLLIHHGE_01094 3.5e-249 ymfH S Peptidase M16
NLLIHHGE_01095 1.1e-139 ymfM S Helix-turn-helix domain
NLLIHHGE_01096 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NLLIHHGE_01097 2.3e-229 cinA 3.5.1.42 S Belongs to the CinA family
NLLIHHGE_01098 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NLLIHHGE_01099 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
NLLIHHGE_01100 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NLLIHHGE_01101 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NLLIHHGE_01102 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NLLIHHGE_01103 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NLLIHHGE_01104 9e-190 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NLLIHHGE_01105 2.8e-31 yajC U Preprotein translocase
NLLIHHGE_01106 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NLLIHHGE_01107 8.3e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NLLIHHGE_01108 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NLLIHHGE_01109 4.1e-43 yrzL S Belongs to the UPF0297 family
NLLIHHGE_01110 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NLLIHHGE_01111 6.1e-48 yrzB S Belongs to the UPF0473 family
NLLIHHGE_01112 1.6e-86 cvpA S Colicin V production protein
NLLIHHGE_01113 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NLLIHHGE_01114 6.1e-54 trxA O Belongs to the thioredoxin family
NLLIHHGE_01115 4.6e-97 yslB S Protein of unknown function (DUF2507)
NLLIHHGE_01116 1.2e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NLLIHHGE_01117 3.3e-101 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NLLIHHGE_01118 5.9e-94 S Phosphoesterase
NLLIHHGE_01119 1.8e-75 ykuL S (CBS) domain
NLLIHHGE_01120 1.2e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
NLLIHHGE_01121 1.7e-146 ykuT M mechanosensitive ion channel
NLLIHHGE_01122 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NLLIHHGE_01123 1.5e-29
NLLIHHGE_01124 3.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NLLIHHGE_01125 2.2e-182 ccpA K catabolite control protein A
NLLIHHGE_01126 4.2e-134
NLLIHHGE_01127 3.5e-132 yebC K Transcriptional regulatory protein
NLLIHHGE_01128 1.2e-180 comGA NU Type II IV secretion system protein
NLLIHHGE_01129 5.4e-184 comGB NU type II secretion system
NLLIHHGE_01130 7.1e-47 comGC U competence protein ComGC
NLLIHHGE_01131 3.7e-78 NU general secretion pathway protein
NLLIHHGE_01132 2.4e-41
NLLIHHGE_01133 4.9e-70
NLLIHHGE_01135 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
NLLIHHGE_01136 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NLLIHHGE_01137 3.8e-113 S Calcineurin-like phosphoesterase
NLLIHHGE_01138 6e-94 yutD S Protein of unknown function (DUF1027)
NLLIHHGE_01139 2.5e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NLLIHHGE_01140 1.8e-105 S Protein of unknown function (DUF1461)
NLLIHHGE_01141 2.1e-109 dedA S SNARE-like domain protein
NLLIHHGE_01142 2.2e-37 XK27_01125 L PFAM IS66 Orf2 family protein
NLLIHHGE_01143 6.5e-153 L Transposase IS66 family
NLLIHHGE_01144 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_01145 2.6e-217 L Integrase core domain
NLLIHHGE_01146 5.2e-169 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NLLIHHGE_01148 5.4e-138 G Peptidase family M23
NLLIHHGE_01149 3.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NLLIHHGE_01150 4.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NLLIHHGE_01151 2.1e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NLLIHHGE_01152 2.7e-149 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NLLIHHGE_01153 6.4e-254 G Peptidase_C39 like family
NLLIHHGE_01154 4.3e-163 yueF S AI-2E family transporter
NLLIHHGE_01155 3.6e-226 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NLLIHHGE_01156 7.4e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NLLIHHGE_01157 0.0 M NlpC/P60 family
NLLIHHGE_01158 0.0 S Peptidase, M23
NLLIHHGE_01159 9.3e-65 gntR1 K Transcriptional regulator, GntR family
NLLIHHGE_01160 4.7e-157 V ABC transporter, ATP-binding protein
NLLIHHGE_01161 5.6e-113
NLLIHHGE_01162 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
NLLIHHGE_01163 2.2e-100 S Pfam:DUF3816
NLLIHHGE_01164 0.0 clpE O Belongs to the ClpA ClpB family
NLLIHHGE_01165 2.9e-27
NLLIHHGE_01166 2.7e-39 ptsH G phosphocarrier protein HPR
NLLIHHGE_01167 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NLLIHHGE_01168 1.9e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NLLIHHGE_01169 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
NLLIHHGE_01170 3.9e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLLIHHGE_01171 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
NLLIHHGE_01172 5.2e-169 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NLLIHHGE_01173 1.5e-236 S Tetratricopeptide repeat protein
NLLIHHGE_01174 6.9e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NLLIHHGE_01175 0.0 yfmR S ABC transporter, ATP-binding protein
NLLIHHGE_01176 4.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NLLIHHGE_01177 2.2e-72 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NLLIHHGE_01178 5.3e-113 hlyIII S protein, hemolysin III
NLLIHHGE_01179 1.4e-150 DegV S EDD domain protein, DegV family
NLLIHHGE_01180 5.2e-170 ypmR E lipolytic protein G-D-S-L family
NLLIHHGE_01181 7.4e-109 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NLLIHHGE_01182 4.4e-35 yozE S Belongs to the UPF0346 family
NLLIHHGE_01183 1.2e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NLLIHHGE_01184 1.7e-142 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NLLIHHGE_01185 9.9e-163 dprA LU DNA protecting protein DprA
NLLIHHGE_01186 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NLLIHHGE_01187 6.4e-170 lacX 5.1.3.3 G Aldose 1-epimerase
NLLIHHGE_01188 3.2e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NLLIHHGE_01189 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLLIHHGE_01190 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NLLIHHGE_01191 2.2e-84 F NUDIX domain
NLLIHHGE_01192 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
NLLIHHGE_01193 4.1e-68 yqkB S Belongs to the HesB IscA family
NLLIHHGE_01194 1.6e-49
NLLIHHGE_01196 1.4e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NLLIHHGE_01197 1.3e-61 asp S Asp23 family, cell envelope-related function
NLLIHHGE_01198 2.3e-24
NLLIHHGE_01199 5.2e-93
NLLIHHGE_01200 1.4e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NLLIHHGE_01201 4.4e-183 K Transcriptional regulator, LacI family
NLLIHHGE_01202 6.3e-233 gntT EG Gluconate
NLLIHHGE_01203 3.8e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NLLIHHGE_01204 2.2e-96 K Acetyltransferase (GNAT) domain
NLLIHHGE_01205 4.2e-47
NLLIHHGE_01206 0.0 nylA 3.5.1.4 J Belongs to the amidase family
NLLIHHGE_01207 2.2e-44
NLLIHHGE_01208 2.8e-58 yhaI S Protein of unknown function (DUF805)
NLLIHHGE_01209 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
NLLIHHGE_01210 6.6e-293 hsdM 2.1.1.72 V type I restriction-modification system
NLLIHHGE_01211 6.9e-74 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
NLLIHHGE_01212 5.8e-177 L Belongs to the 'phage' integrase family
NLLIHHGE_01213 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_01214 2.6e-217 L Integrase core domain
NLLIHHGE_01215 5.2e-169 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
NLLIHHGE_01216 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NLLIHHGE_01217 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NLLIHHGE_01218 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NLLIHHGE_01219 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NLLIHHGE_01220 8.5e-14 M Lysin motif
NLLIHHGE_01221 1.2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NLLIHHGE_01222 1.2e-191 ypbB 5.1.3.1 S Helix-turn-helix domain
NLLIHHGE_01223 2e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NLLIHHGE_01224 5.8e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NLLIHHGE_01225 2.2e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NLLIHHGE_01226 8.4e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NLLIHHGE_01227 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NLLIHHGE_01228 1.7e-165 xerD D recombinase XerD
NLLIHHGE_01229 7.9e-168 cvfB S S1 domain
NLLIHHGE_01230 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NLLIHHGE_01231 0.0 dnaE 2.7.7.7 L DNA polymerase
NLLIHHGE_01232 2.3e-30 S Protein of unknown function (DUF2929)
NLLIHHGE_01234 8.1e-11
NLLIHHGE_01236 3.9e-132 lysA2 M Glycosyl hydrolases family 25
NLLIHHGE_01237 8.7e-42 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NLLIHHGE_01238 3e-10
NLLIHHGE_01239 5.1e-63 S Domain of unknown function (DUF2479)
NLLIHHGE_01240 2.4e-76 3.2.1.11 GH66 G Glycosyl hydrolase family 66
NLLIHHGE_01242 2.1e-27
NLLIHHGE_01243 7.2e-288 M Prophage endopeptidase tail
NLLIHHGE_01244 1.6e-141 S Phage tail protein
NLLIHHGE_01245 1.7e-220 M Phage tail tape measure protein TP901
NLLIHHGE_01246 4.7e-19
NLLIHHGE_01247 2.4e-66 S Phage tail tube protein
NLLIHHGE_01248 3e-26
NLLIHHGE_01249 7.5e-21
NLLIHHGE_01250 3.1e-38 S Phage head-tail joining protein
NLLIHHGE_01251 2.6e-45 S Phage gp6-like head-tail connector protein
NLLIHHGE_01252 1.5e-131 S Phage capsid family
NLLIHHGE_01253 2.3e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NLLIHHGE_01254 4.9e-145 S portal protein
NLLIHHGE_01255 5.5e-269 S Phage Terminase
NLLIHHGE_01256 4.2e-80 L Phage terminase, small subunit
NLLIHHGE_01257 4.6e-52 L HNH nucleases
NLLIHHGE_01270 5.3e-37
NLLIHHGE_01272 1.1e-133 pnuC H nicotinamide mononucleotide transporter
NLLIHHGE_01283 8.8e-208 XK27_11280 S Psort location CytoplasmicMembrane, score
NLLIHHGE_01284 0.0
NLLIHHGE_01286 1.9e-74 S Transcriptional regulator, RinA family
NLLIHHGE_01290 1.1e-84 S nucleoside kinase activity
NLLIHHGE_01296 2e-135
NLLIHHGE_01302 2.4e-72 rusA L Endodeoxyribonuclease RusA
NLLIHHGE_01303 1.4e-32
NLLIHHGE_01304 5.4e-94 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
NLLIHHGE_01306 5.4e-124 L Psort location Cytoplasmic, score
NLLIHHGE_01307 2.5e-129 S Putative HNHc nuclease
NLLIHHGE_01308 1.2e-54 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NLLIHHGE_01313 2.4e-08
NLLIHHGE_01315 3e-112 S Protein of unknown function (DUF3102)
NLLIHHGE_01316 6.5e-17 K Helix-turn-helix XRE-family like proteins
NLLIHHGE_01317 4.3e-47 K Cro/C1-type HTH DNA-binding domain
NLLIHHGE_01318 6.1e-76 E IrrE N-terminal-like domain
NLLIHHGE_01324 4.3e-94 L Belongs to the 'phage' integrase family
NLLIHHGE_01325 9.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NLLIHHGE_01326 1.7e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NLLIHHGE_01327 3.2e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
NLLIHHGE_01328 4.8e-221 patA 2.6.1.1 E Aminotransferase
NLLIHHGE_01329 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NLLIHHGE_01330 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NLLIHHGE_01331 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NLLIHHGE_01332 4.5e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NLLIHHGE_01333 2.6e-146 recO L Involved in DNA repair and RecF pathway recombination
NLLIHHGE_01334 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NLLIHHGE_01335 1.7e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NLLIHHGE_01336 7.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NLLIHHGE_01337 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
NLLIHHGE_01338 9.3e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NLLIHHGE_01339 4.3e-90 bioY S BioY family
NLLIHHGE_01340 4.1e-264 argH 4.3.2.1 E argininosuccinate lyase
NLLIHHGE_01341 2.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NLLIHHGE_01342 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NLLIHHGE_01343 4.7e-68 yqeY S YqeY-like protein
NLLIHHGE_01344 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NLLIHHGE_01345 1.1e-265 glnPH2 P ABC transporter permease
NLLIHHGE_01346 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLLIHHGE_01347 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NLLIHHGE_01348 2.7e-165 yniA G Phosphotransferase enzyme family
NLLIHHGE_01349 2.7e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NLLIHHGE_01350 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NLLIHHGE_01351 1.3e-51
NLLIHHGE_01352 1.9e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NLLIHHGE_01353 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
NLLIHHGE_01354 2.8e-57
NLLIHHGE_01356 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NLLIHHGE_01357 3.6e-199 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NLLIHHGE_01358 1.8e-275 pipD E Dipeptidase
NLLIHHGE_01359 1e-23 S Coenzyme PQQ synthesis protein D (PqqD)
NLLIHHGE_01360 3e-196 S OPT oligopeptide transporter protein
NLLIHHGE_01361 2e-14
NLLIHHGE_01364 8.4e-114 3.4.21.88 K Peptidase S24-like
NLLIHHGE_01365 8.2e-17
NLLIHHGE_01366 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_01367 2.6e-217 L Integrase core domain
NLLIHHGE_01368 6.1e-199 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NLLIHHGE_01369 1.2e-114 S Membrane
NLLIHHGE_01370 3.4e-126 O Zinc-dependent metalloprotease
NLLIHHGE_01371 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NLLIHHGE_01372 9.5e-158 metQ_4 P Belongs to the nlpA lipoprotein family
NLLIHHGE_01374 0.0 UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_01375 0.0 UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_01376 0.0 UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_01377 0.0 UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_01378 1.4e-182 S Phosphotransferase system, EIIC
NLLIHHGE_01379 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NLLIHHGE_01380 2.9e-169
NLLIHHGE_01381 4.2e-52 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NLLIHHGE_01382 7e-206 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NLLIHHGE_01383 1e-159 K LysR substrate binding domain
NLLIHHGE_01384 1.5e-143 manA 5.3.1.8 G mannose-6-phosphate isomerase
NLLIHHGE_01385 1.1e-92 lysR5 K LysR substrate binding domain
NLLIHHGE_01386 3e-110 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NLLIHHGE_01387 4.4e-97 2.3.1.128 K acetyltransferase
NLLIHHGE_01388 9e-184
NLLIHHGE_01389 2.6e-17 K Transcriptional regulator, HxlR family
NLLIHHGE_01390 1.4e-223 P ammonium transporter
NLLIHHGE_01391 1.9e-97 ureI S AmiS/UreI family transporter
NLLIHHGE_01392 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
NLLIHHGE_01393 2.9e-63 ureB 3.5.1.5 E Urease beta subunit
NLLIHHGE_01394 0.0 ureC 3.5.1.5 E Amidohydrolase family
NLLIHHGE_01395 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
NLLIHHGE_01396 2.1e-131 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NLLIHHGE_01397 4.7e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
NLLIHHGE_01398 2.8e-162 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
NLLIHHGE_01399 8.4e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLLIHHGE_01400 6.9e-74 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NLLIHHGE_01401 2.2e-182 nikMN P PDGLE domain
NLLIHHGE_01402 3.8e-135 P Cobalt transport protein
NLLIHHGE_01403 1.1e-135 cbiO P ABC transporter
NLLIHHGE_01404 1.3e-128 K Transcriptional regulatory protein, C-terminal domain protein
NLLIHHGE_01405 1.5e-158 pstS P Phosphate
NLLIHHGE_01406 6.6e-154 pstC P probably responsible for the translocation of the substrate across the membrane
NLLIHHGE_01407 6.5e-154 pstA P Phosphate transport system permease protein PstA
NLLIHHGE_01408 1.2e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NLLIHHGE_01409 3.9e-125 phoU P Plays a role in the regulation of phosphate uptake
NLLIHHGE_01410 1e-143
NLLIHHGE_01411 7.7e-244 ydaM M Glycosyl transferase
NLLIHHGE_01412 4.4e-219 G Glycosyl hydrolases family 8
NLLIHHGE_01413 1.9e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NLLIHHGE_01414 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NLLIHHGE_01415 2e-239 ktrB P Potassium uptake protein
NLLIHHGE_01416 1.4e-116 ktrA P domain protein
NLLIHHGE_01417 4.5e-81 Q Methyltransferase
NLLIHHGE_01420 1.1e-11
NLLIHHGE_01424 4.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
NLLIHHGE_01425 1.9e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NLLIHHGE_01426 1.6e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NLLIHHGE_01427 1.9e-95 S NADPH-dependent FMN reductase
NLLIHHGE_01428 1.6e-180 MA20_14895 S Conserved hypothetical protein 698
NLLIHHGE_01429 3.2e-135 I alpha/beta hydrolase fold
NLLIHHGE_01430 1.1e-169 lsa S ABC transporter
NLLIHHGE_01431 2.8e-179 yfeX P Peroxidase
NLLIHHGE_01432 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
NLLIHHGE_01433 7.8e-260 ytjP 3.5.1.18 E Dipeptidase
NLLIHHGE_01434 6.3e-216 uhpT EGP Major facilitator Superfamily
NLLIHHGE_01435 6.5e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
NLLIHHGE_01436 7.7e-130 ponA V Beta-lactamase enzyme family
NLLIHHGE_01437 1.5e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NLLIHHGE_01438 6.7e-75
NLLIHHGE_01439 1.6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NLLIHHGE_01440 5.8e-22
NLLIHHGE_01443 6.4e-265 S Uncharacterized protein conserved in bacteria (DUF2252)
NLLIHHGE_01444 3.7e-298 L PFAM plasmid pRiA4b ORF-3 family protein
NLLIHHGE_01445 5.1e-206 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
NLLIHHGE_01446 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NLLIHHGE_01447 7.8e-155 mleR K LysR family
NLLIHHGE_01448 1.4e-306 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NLLIHHGE_01449 2.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NLLIHHGE_01450 6.4e-265 frdC 1.3.5.4 C FAD binding domain
NLLIHHGE_01451 7e-251 yflS P Sodium:sulfate symporter transmembrane region
NLLIHHGE_01452 1.4e-159 mleR K LysR family
NLLIHHGE_01453 4.7e-252 yjjP S Putative threonine/serine exporter
NLLIHHGE_01454 4.2e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
NLLIHHGE_01455 1.1e-276 emrY EGP Major facilitator Superfamily
NLLIHHGE_01456 1.9e-186 I Alpha beta
NLLIHHGE_01457 6.3e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NLLIHHGE_01458 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NLLIHHGE_01460 5.2e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NLLIHHGE_01461 3.3e-119 S Domain of unknown function (DUF4811)
NLLIHHGE_01462 2.7e-269 lmrB EGP Major facilitator Superfamily
NLLIHHGE_01463 5.7e-74 merR K MerR HTH family regulatory protein
NLLIHHGE_01464 1.8e-54
NLLIHHGE_01465 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NLLIHHGE_01466 9.2e-220 S CAAX protease self-immunity
NLLIHHGE_01467 1.4e-108 glnP P ABC transporter permease
NLLIHHGE_01468 3.2e-110 gluC P ABC transporter permease
NLLIHHGE_01469 5.7e-152 glnH ET ABC transporter
NLLIHHGE_01470 5.9e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLLIHHGE_01471 2.7e-82 usp1 T Belongs to the universal stress protein A family
NLLIHHGE_01472 6.4e-109 S VIT family
NLLIHHGE_01473 2.9e-117 S membrane
NLLIHHGE_01474 9.1e-167 czcD P cation diffusion facilitator family transporter
NLLIHHGE_01475 2.4e-124 sirR K iron dependent repressor
NLLIHHGE_01476 1e-30 cspC K Cold shock protein
NLLIHHGE_01477 8.1e-129 thrE S Putative threonine/serine exporter
NLLIHHGE_01478 3.9e-81 S Threonine/Serine exporter, ThrE
NLLIHHGE_01479 2.3e-119 lssY 3.6.1.27 I phosphatase
NLLIHHGE_01480 1.4e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
NLLIHHGE_01481 2.3e-276 lysP E amino acid
NLLIHHGE_01482 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NLLIHHGE_01488 8.8e-181 S Hydrolases of the alpha beta superfamily
NLLIHHGE_01489 3.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
NLLIHHGE_01490 1.3e-76 ctsR K Belongs to the CtsR family
NLLIHHGE_01491 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NLLIHHGE_01492 1e-110 K Bacterial regulatory proteins, tetR family
NLLIHHGE_01493 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLLIHHGE_01494 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLLIHHGE_01495 6.1e-200 ykiI
NLLIHHGE_01496 3.4e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NLLIHHGE_01497 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NLLIHHGE_01498 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NLLIHHGE_01499 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NLLIHHGE_01500 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NLLIHHGE_01501 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NLLIHHGE_01502 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NLLIHHGE_01503 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NLLIHHGE_01504 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NLLIHHGE_01505 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NLLIHHGE_01506 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NLLIHHGE_01507 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NLLIHHGE_01508 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NLLIHHGE_01509 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
NLLIHHGE_01510 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NLLIHHGE_01511 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NLLIHHGE_01512 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NLLIHHGE_01513 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NLLIHHGE_01514 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NLLIHHGE_01515 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NLLIHHGE_01516 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NLLIHHGE_01517 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NLLIHHGE_01518 2.9e-24 rpmD J Ribosomal protein L30
NLLIHHGE_01519 8.9e-64 rplO J Binds to the 23S rRNA
NLLIHHGE_01520 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NLLIHHGE_01521 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NLLIHHGE_01522 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NLLIHHGE_01523 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NLLIHHGE_01524 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NLLIHHGE_01525 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NLLIHHGE_01526 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NLLIHHGE_01527 1.1e-62 rplQ J Ribosomal protein L17
NLLIHHGE_01528 1.5e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLLIHHGE_01529 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLLIHHGE_01530 1.2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NLLIHHGE_01531 6.5e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NLLIHHGE_01532 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NLLIHHGE_01533 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NLLIHHGE_01534 9.4e-141 IQ reductase
NLLIHHGE_01535 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
NLLIHHGE_01536 1.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NLLIHHGE_01537 1.2e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NLLIHHGE_01538 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NLLIHHGE_01539 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NLLIHHGE_01540 1.2e-202 camS S sex pheromone
NLLIHHGE_01541 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLLIHHGE_01542 3.5e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NLLIHHGE_01543 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NLLIHHGE_01544 3.5e-188 yegS 2.7.1.107 G Lipid kinase
NLLIHHGE_01545 4.5e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NLLIHHGE_01546 6.1e-226 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
NLLIHHGE_01547 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
NLLIHHGE_01548 6.6e-24
NLLIHHGE_01551 2.2e-171 L Plasmid pRiA4b ORF-3-like protein
NLLIHHGE_01552 1.9e-61 XK27_04080 H Riboflavin biosynthesis protein RibD
NLLIHHGE_01553 6.6e-44 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
NLLIHHGE_01554 2.9e-58 S Protein of unknown function (DUF3021)
NLLIHHGE_01555 5.8e-74 K LytTr DNA-binding domain
NLLIHHGE_01556 2.4e-145 cylB V ABC-2 type transporter
NLLIHHGE_01557 5.7e-155 cylA V ABC transporter
NLLIHHGE_01558 2.9e-48
NLLIHHGE_01560 5.8e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NLLIHHGE_01561 2.2e-205 amtB P ammonium transporter
NLLIHHGE_01562 8.6e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
NLLIHHGE_01563 1.4e-90 S B3 4 domain
NLLIHHGE_01564 1.1e-90
NLLIHHGE_01565 4.4e-123 pnb C nitroreductase
NLLIHHGE_01566 4.1e-75 ogt 2.1.1.63 L Methyltransferase
NLLIHHGE_01567 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
NLLIHHGE_01568 2.8e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NLLIHHGE_01569 7.3e-69 S Protein of unknown function (DUF3021)
NLLIHHGE_01570 6.4e-78 K LytTr DNA-binding domain
NLLIHHGE_01571 4.8e-93 K Acetyltransferase (GNAT) family
NLLIHHGE_01572 3.7e-22
NLLIHHGE_01573 1.1e-119 ybhL S Belongs to the BI1 family
NLLIHHGE_01574 2.2e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NLLIHHGE_01575 4.2e-197 S Protein of unknown function (DUF3114)
NLLIHHGE_01576 1.8e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NLLIHHGE_01577 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NLLIHHGE_01578 5e-110 yvdD 3.2.2.10 S Belongs to the LOG family
NLLIHHGE_01579 9.1e-62 S Domain of unknown function (DUF4828)
NLLIHHGE_01580 1.3e-190 mocA S Oxidoreductase
NLLIHHGE_01581 6.7e-232 yfmL L DEAD DEAH box helicase
NLLIHHGE_01583 2.4e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NLLIHHGE_01584 4.9e-57
NLLIHHGE_01585 1.5e-74 gtcA S Teichoic acid glycosylation protein
NLLIHHGE_01586 4.7e-79 fld C Flavodoxin
NLLIHHGE_01587 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
NLLIHHGE_01588 7.1e-222 arcT 2.6.1.1 E Aminotransferase
NLLIHHGE_01589 1e-257 E Arginine ornithine antiporter
NLLIHHGE_01590 1.4e-281 yjeM E Amino Acid
NLLIHHGE_01591 1.6e-152 yihY S Belongs to the UPF0761 family
NLLIHHGE_01592 6.6e-34 S Protein of unknown function (DUF2922)
NLLIHHGE_01593 4.9e-31
NLLIHHGE_01594 3.7e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
NLLIHHGE_01595 8.7e-147 cps1D M Domain of unknown function (DUF4422)
NLLIHHGE_01596 1.2e-174 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NLLIHHGE_01597 1.3e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
NLLIHHGE_01598 0.0 2.7.7.6 M Peptidase family M23
NLLIHHGE_01599 0.0 G Peptidase_C39 like family
NLLIHHGE_01600 2.7e-25
NLLIHHGE_01601 1.4e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
NLLIHHGE_01602 1.7e-215 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NLLIHHGE_01603 3.1e-77 rgpB GT2 M Glycosyl transferase family 2
NLLIHHGE_01604 5e-118 S Glycosyltransferase like family 2
NLLIHHGE_01605 7.1e-103 M Glycosyltransferase like family 2
NLLIHHGE_01606 9.4e-92 cps3F
NLLIHHGE_01607 4.8e-42 M biosynthesis protein
NLLIHHGE_01608 1.8e-86 M Domain of unknown function (DUF4422)
NLLIHHGE_01609 3.1e-83 S Glycosyltransferase like family
NLLIHHGE_01610 1.4e-132 S CytoplasmicMembrane, score 9.99
NLLIHHGE_01611 1.1e-72 S Bacterial membrane protein, YfhO
NLLIHHGE_01612 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLLIHHGE_01614 2.6e-217 L Integrase core domain
NLLIHHGE_01615 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_01616 7.8e-24
NLLIHHGE_01617 4e-75
NLLIHHGE_01618 1.1e-30
NLLIHHGE_01619 9.4e-141 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NLLIHHGE_01620 3.9e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NLLIHHGE_01621 9.8e-103 fic D Fic/DOC family
NLLIHHGE_01622 1.3e-70
NLLIHHGE_01623 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
NLLIHHGE_01624 2.7e-91 L nuclease
NLLIHHGE_01625 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NLLIHHGE_01626 1.5e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NLLIHHGE_01627 2.5e-177 M Glycosyl hydrolases family 25
NLLIHHGE_01628 1.8e-144 ywqE 3.1.3.48 GM PHP domain protein
NLLIHHGE_01630 4e-37
NLLIHHGE_01631 1.5e-67 T Toxin-antitoxin system, toxin component, MazF family
NLLIHHGE_01633 3.4e-250 mmuP E amino acid
NLLIHHGE_01634 8.9e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NLLIHHGE_01635 5.3e-283 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NLLIHHGE_01636 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
NLLIHHGE_01637 0.0 ganB 3.2.1.89 G arabinogalactan
NLLIHHGE_01638 1.8e-24 S Acyltransferase family
NLLIHHGE_01640 4.6e-48 S Glycosyltransferase like family 2
NLLIHHGE_01641 1.3e-30 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NLLIHHGE_01642 2.7e-31 2.7.8.12 M Glycosyltransferase, group 2 family protein
NLLIHHGE_01643 1.7e-30 M Glycosyltransferase sugar-binding region containing DXD motif
NLLIHHGE_01644 4.8e-72 cps2I S Psort location CytoplasmicMembrane, score
NLLIHHGE_01646 3.6e-38 GT2,GT4 M Glycosyltransferase GT-D fold
NLLIHHGE_01647 4e-67 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
NLLIHHGE_01648 7e-87 GT4 G Glycosyl transferase 4-like
NLLIHHGE_01649 4.2e-48 pglC M Bacterial sugar transferase
NLLIHHGE_01650 3.1e-104 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NLLIHHGE_01651 5.2e-99 epsB M biosynthesis protein
NLLIHHGE_01655 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NLLIHHGE_01656 1.3e-153
NLLIHHGE_01657 5.1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NLLIHHGE_01658 2.5e-244 purD 6.3.4.13 F Belongs to the GARS family
NLLIHHGE_01659 1e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NLLIHHGE_01660 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NLLIHHGE_01661 5.8e-194 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NLLIHHGE_01662 4e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NLLIHHGE_01663 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLLIHHGE_01664 8.9e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLLIHHGE_01665 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NLLIHHGE_01666 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NLLIHHGE_01667 2.4e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NLLIHHGE_01668 2.3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NLLIHHGE_01669 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NLLIHHGE_01670 1.5e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
NLLIHHGE_01671 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NLLIHHGE_01672 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NLLIHHGE_01673 4.7e-172 K AI-2E family transporter
NLLIHHGE_01674 7.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NLLIHHGE_01675 5.3e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
NLLIHHGE_01676 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NLLIHHGE_01677 1.3e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NLLIHHGE_01678 2.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NLLIHHGE_01679 1.1e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NLLIHHGE_01680 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NLLIHHGE_01681 1.5e-139 K LysR substrate binding domain
NLLIHHGE_01682 3.6e-52 azlD S branched-chain amino acid
NLLIHHGE_01683 1.9e-140 azlC E AzlC protein
NLLIHHGE_01684 3.7e-202 hpk31 2.7.13.3 T Histidine kinase
NLLIHHGE_01685 3.8e-125 K response regulator
NLLIHHGE_01686 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NLLIHHGE_01687 1.6e-171 deoR K sugar-binding domain protein
NLLIHHGE_01688 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NLLIHHGE_01689 2.6e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
NLLIHHGE_01690 4.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NLLIHHGE_01691 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NLLIHHGE_01692 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
NLLIHHGE_01693 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NLLIHHGE_01694 2e-31 yyzM S Bacterial protein of unknown function (DUF951)
NLLIHHGE_01695 8.5e-154 spo0J K Belongs to the ParB family
NLLIHHGE_01696 3.6e-140 soj D Sporulation initiation inhibitor
NLLIHHGE_01697 2.5e-146 noc K Belongs to the ParB family
NLLIHHGE_01698 1.2e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NLLIHHGE_01699 1.9e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
NLLIHHGE_01700 6.6e-170 rihC 3.2.2.1 F Nucleoside
NLLIHHGE_01701 1e-218 nupG F Nucleoside transporter
NLLIHHGE_01702 1.5e-221 cycA E Amino acid permease
NLLIHHGE_01703 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NLLIHHGE_01704 1.8e-265 glnP P ABC transporter
NLLIHHGE_01705 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NLLIHHGE_01706 3.3e-221 UW LPXTG-motif cell wall anchor domain protein
NLLIHHGE_01708 5.8e-112 lssY 3.6.1.27 I Acid phosphatase homologues
NLLIHHGE_01709 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NLLIHHGE_01710 2.7e-230 clcA_2 P Chloride transporter, ClC family
NLLIHHGE_01711 1.4e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NLLIHHGE_01712 1.9e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NLLIHHGE_01713 7.5e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NLLIHHGE_01714 1.2e-51
NLLIHHGE_01715 0.0 S SEC-C Motif Domain Protein
NLLIHHGE_01716 1.7e-87 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NLLIHHGE_01717 6.9e-13 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NLLIHHGE_01718 2.5e-74
NLLIHHGE_01719 5e-176
NLLIHHGE_01720 4.5e-175 fecB P Periplasmic binding protein
NLLIHHGE_01721 1.7e-126 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
NLLIHHGE_01722 1e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NLLIHHGE_01723 3.5e-79 S Flavodoxin
NLLIHHGE_01724 9.1e-63 moaE 2.8.1.12 H MoaE protein
NLLIHHGE_01725 1.1e-31 moaD 2.8.1.12 H ThiS family
NLLIHHGE_01726 1.5e-217 narK P Transporter, major facilitator family protein
NLLIHHGE_01727 3.7e-144 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
NLLIHHGE_01728 1.8e-173
NLLIHHGE_01729 3.6e-18
NLLIHHGE_01730 4.9e-114 nreC K PFAM regulatory protein LuxR
NLLIHHGE_01731 8e-183 comP 2.7.13.3 F Sensor histidine kinase
NLLIHHGE_01732 6.3e-42
NLLIHHGE_01733 7.6e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NLLIHHGE_01734 7.5e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NLLIHHGE_01735 3.3e-225 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
NLLIHHGE_01736 1.2e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NLLIHHGE_01737 5.7e-186 moeB 2.7.7.73, 2.7.7.80 H ThiF family
NLLIHHGE_01738 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NLLIHHGE_01739 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
NLLIHHGE_01740 2.5e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
NLLIHHGE_01741 3.3e-129 narI 1.7.5.1 C Nitrate reductase
NLLIHHGE_01742 6.5e-154 EG EamA-like transporter family
NLLIHHGE_01743 2.5e-118 L Integrase
NLLIHHGE_01744 5e-159 rssA S Phospholipase, patatin family
NLLIHHGE_01745 4.6e-202 xerS L Belongs to the 'phage' integrase family
NLLIHHGE_01747 2.8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLLIHHGE_01748 1.6e-76 marR K Transcriptional regulator, MarR family
NLLIHHGE_01749 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NLLIHHGE_01750 1.5e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLLIHHGE_01751 5.2e-157 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NLLIHHGE_01752 1.6e-129 IQ reductase
NLLIHHGE_01753 4.4e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NLLIHHGE_01754 1.3e-70 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NLLIHHGE_01755 2.5e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NLLIHHGE_01756 7.5e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NLLIHHGE_01757 9.3e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NLLIHHGE_01758 3.4e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NLLIHHGE_01759 7.1e-133 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NLLIHHGE_01768 1.1e-54
NLLIHHGE_01769 9.7e-115 frnE Q DSBA-like thioredoxin domain
NLLIHHGE_01770 3.7e-162 I alpha/beta hydrolase fold
NLLIHHGE_01771 8.5e-20 K Helix-turn-helix XRE-family like proteins
NLLIHHGE_01772 3.3e-35 S Phage derived protein Gp49-like (DUF891)
NLLIHHGE_01774 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_01775 2.6e-217 L Integrase core domain
NLLIHHGE_01776 1e-125 L Transposase IS66 family
NLLIHHGE_01777 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
NLLIHHGE_01779 7.8e-55 L Transposase IS66 family
NLLIHHGE_01780 4.6e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
NLLIHHGE_01781 2.2e-236 lmrB EGP Major facilitator Superfamily
NLLIHHGE_01782 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NLLIHHGE_01783 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NLLIHHGE_01784 3.6e-160 sufD O Uncharacterized protein family (UPF0051)
NLLIHHGE_01785 1.6e-42 lytE M LysM domain protein
NLLIHHGE_01786 0.0 oppD EP Psort location Cytoplasmic, score
NLLIHHGE_01787 1.1e-87 lytE M LysM domain protein
NLLIHHGE_01788 7.1e-149 xth 3.1.11.2 L exodeoxyribonuclease III
NLLIHHGE_01789 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
NLLIHHGE_01790 2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
NLLIHHGE_01791 1.5e-152 yeaE S Aldo keto
NLLIHHGE_01792 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
NLLIHHGE_01793 1.8e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NLLIHHGE_01794 4.5e-79 S Psort location Cytoplasmic, score
NLLIHHGE_01795 7.7e-86 S Short repeat of unknown function (DUF308)
NLLIHHGE_01796 1e-23
NLLIHHGE_01797 8.2e-102 V VanZ like family
NLLIHHGE_01798 8.2e-233 cycA E Amino acid permease
NLLIHHGE_01799 4.3e-85 perR P Belongs to the Fur family
NLLIHHGE_01800 2.4e-259 EGP Major facilitator Superfamily
NLLIHHGE_01801 7.9e-94 tag 3.2.2.20 L glycosylase
NLLIHHGE_01802 1.6e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NLLIHHGE_01803 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NLLIHHGE_01804 1.7e-41
NLLIHHGE_01805 3e-301 ytgP S Polysaccharide biosynthesis protein
NLLIHHGE_01806 1.6e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NLLIHHGE_01807 4.8e-276 pepV 3.5.1.18 E dipeptidase PepV
NLLIHHGE_01808 1.9e-86 uspA T Belongs to the universal stress protein A family
NLLIHHGE_01809 5.7e-178 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NLLIHHGE_01810 1.5e-115 dck 2.7.1.74 F deoxynucleoside kinase
NLLIHHGE_01811 7.2e-112
NLLIHHGE_01812 4.8e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
NLLIHHGE_01813 1.8e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NLLIHHGE_01814 2.1e-32
NLLIHHGE_01815 1.2e-118 S CAAX protease self-immunity
NLLIHHGE_01816 1.9e-43
NLLIHHGE_01818 1.2e-25
NLLIHHGE_01819 5.9e-24
NLLIHHGE_01820 1.3e-142 S Domain of unknown function DUF1829
NLLIHHGE_01821 3.6e-72
NLLIHHGE_01822 5.3e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NLLIHHGE_01823 7e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NLLIHHGE_01824 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NLLIHHGE_01825 5.1e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NLLIHHGE_01826 9.1e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NLLIHHGE_01827 2.3e-215 folP 2.5.1.15 H dihydropteroate synthase
NLLIHHGE_01828 1e-43
NLLIHHGE_01829 3.3e-40
NLLIHHGE_01831 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NLLIHHGE_01832 2.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NLLIHHGE_01833 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NLLIHHGE_01834 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NLLIHHGE_01835 9.4e-38 yheA S Belongs to the UPF0342 family
NLLIHHGE_01836 2.2e-218 yhaO L Ser Thr phosphatase family protein
NLLIHHGE_01837 0.0 L AAA domain
NLLIHHGE_01838 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NLLIHHGE_01840 8.3e-78 hit FG histidine triad
NLLIHHGE_01841 3.9e-136 ecsA V ABC transporter, ATP-binding protein
NLLIHHGE_01842 4.3e-217 ecsB U ABC transporter
NLLIHHGE_01843 8.1e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NLLIHHGE_01844 0.0 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
NLLIHHGE_01845 1.8e-260 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NLLIHHGE_01846 4.3e-183 iolS C Aldo keto reductase
NLLIHHGE_01847 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
NLLIHHGE_01848 7.5e-58 ytzB S Small secreted protein
NLLIHHGE_01849 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NLLIHHGE_01850 2.7e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLLIHHGE_01851 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NLLIHHGE_01852 1.9e-119 ybhL S Belongs to the BI1 family
NLLIHHGE_01853 8.3e-117 yoaK S Protein of unknown function (DUF1275)
NLLIHHGE_01854 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NLLIHHGE_01855 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NLLIHHGE_01856 3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NLLIHHGE_01857 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NLLIHHGE_01858 4.4e-226 dnaB L replication initiation and membrane attachment
NLLIHHGE_01859 2.4e-170 dnaI L Primosomal protein DnaI
NLLIHHGE_01860 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NLLIHHGE_01861 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NLLIHHGE_01862 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NLLIHHGE_01863 1.3e-96 yqeG S HAD phosphatase, family IIIA
NLLIHHGE_01864 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
NLLIHHGE_01865 1.9e-47 yhbY J RNA-binding protein
NLLIHHGE_01866 6.7e-124 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NLLIHHGE_01867 3.5e-114 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NLLIHHGE_01868 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NLLIHHGE_01869 1.7e-139 yqeM Q Methyltransferase
NLLIHHGE_01870 5.1e-212 ylbM S Belongs to the UPF0348 family
NLLIHHGE_01871 2.9e-99 yceD S Uncharacterized ACR, COG1399
NLLIHHGE_01872 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NLLIHHGE_01873 1.5e-121 K response regulator
NLLIHHGE_01874 4.1e-278 arlS 2.7.13.3 T Histidine kinase
NLLIHHGE_01875 4.3e-267 yjeM E Amino Acid
NLLIHHGE_01876 8.3e-230 V MatE
NLLIHHGE_01877 7.4e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NLLIHHGE_01878 2.9e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NLLIHHGE_01879 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NLLIHHGE_01880 4.8e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NLLIHHGE_01881 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NLLIHHGE_01882 6.7e-59 yodB K Transcriptional regulator, HxlR family
NLLIHHGE_01883 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NLLIHHGE_01884 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NLLIHHGE_01885 3e-116 rlpA M PFAM NLP P60 protein
NLLIHHGE_01886 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
NLLIHHGE_01887 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NLLIHHGE_01888 2.6e-70 yneR S Belongs to the HesB IscA family
NLLIHHGE_01889 0.0 S membrane
NLLIHHGE_01890 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NLLIHHGE_01891 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NLLIHHGE_01892 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NLLIHHGE_01893 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
NLLIHHGE_01894 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NLLIHHGE_01895 1.5e-183 glk 2.7.1.2 G Glucokinase
NLLIHHGE_01896 3.4e-67 yqhL P Rhodanese-like protein
NLLIHHGE_01897 5.9e-22 S Protein of unknown function (DUF3042)
NLLIHHGE_01898 3.1e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NLLIHHGE_01899 1.4e-264 glnA 6.3.1.2 E glutamine synthetase
NLLIHHGE_01900 1.2e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NLLIHHGE_01901 1.1e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NLLIHHGE_01902 3.9e-12
NLLIHHGE_01903 3.3e-155 P Belongs to the nlpA lipoprotein family
NLLIHHGE_01904 1.6e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NLLIHHGE_01905 1.4e-50 S Iron-sulfur cluster assembly protein
NLLIHHGE_01906 1e-151
NLLIHHGE_01907 4.4e-178
NLLIHHGE_01908 2.5e-89 dut S Protein conserved in bacteria
NLLIHHGE_01911 2.6e-112 K Transcriptional regulator
NLLIHHGE_01912 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
NLLIHHGE_01913 7.4e-55 ysxB J Cysteine protease Prp
NLLIHHGE_01914 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NLLIHHGE_01915 2.4e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NLLIHHGE_01916 2.4e-203 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NLLIHHGE_01917 1.6e-115 J 2'-5' RNA ligase superfamily
NLLIHHGE_01918 2.2e-70 yqhY S Asp23 family, cell envelope-related function
NLLIHHGE_01919 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NLLIHHGE_01920 2.7e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NLLIHHGE_01921 1.5e-223 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLLIHHGE_01922 2.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NLLIHHGE_01923 1.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NLLIHHGE_01924 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NLLIHHGE_01925 3.3e-77 argR K Regulates arginine biosynthesis genes
NLLIHHGE_01926 3.3e-263 recN L May be involved in recombinational repair of damaged DNA
NLLIHHGE_01927 1.7e-54
NLLIHHGE_01928 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NLLIHHGE_01929 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NLLIHHGE_01930 2.4e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NLLIHHGE_01931 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NLLIHHGE_01932 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NLLIHHGE_01933 2.8e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NLLIHHGE_01934 2.9e-131 stp 3.1.3.16 T phosphatase
NLLIHHGE_01935 0.0 KLT serine threonine protein kinase
NLLIHHGE_01936 5.3e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NLLIHHGE_01937 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NLLIHHGE_01938 5.3e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NLLIHHGE_01939 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NLLIHHGE_01940 4.7e-58 asp S Asp23 family, cell envelope-related function
NLLIHHGE_01941 0.0 yloV S DAK2 domain fusion protein YloV
NLLIHHGE_01942 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NLLIHHGE_01943 2.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NLLIHHGE_01944 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NLLIHHGE_01945 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NLLIHHGE_01946 0.0 smc D Required for chromosome condensation and partitioning
NLLIHHGE_01947 1.8e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NLLIHHGE_01948 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NLLIHHGE_01949 1e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NLLIHHGE_01950 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NLLIHHGE_01951 4.1e-40 ylqC S Belongs to the UPF0109 family
NLLIHHGE_01952 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NLLIHHGE_01953 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NLLIHHGE_01954 1.3e-260 yfnA E amino acid
NLLIHHGE_01955 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NLLIHHGE_01956 1.7e-34
NLLIHHGE_01957 3.5e-52 S Mazg nucleotide pyrophosphohydrolase
NLLIHHGE_01958 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
NLLIHHGE_01959 1.5e-83
NLLIHHGE_01960 1e-187 lacR K Transcriptional regulator
NLLIHHGE_01961 0.0 lacS G Transporter
NLLIHHGE_01962 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NLLIHHGE_01963 1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NLLIHHGE_01964 3.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NLLIHHGE_01965 3.9e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
NLLIHHGE_01966 5.5e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
NLLIHHGE_01967 5.2e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NLLIHHGE_01968 8.2e-224 mdtG EGP Major facilitator Superfamily
NLLIHHGE_01969 6.4e-167 T Calcineurin-like phosphoesterase superfamily domain
NLLIHHGE_01970 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NLLIHHGE_01972 9.9e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NLLIHHGE_01973 2e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NLLIHHGE_01974 1.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
NLLIHHGE_01975 0.0 trxB2 1.8.1.9 C Thioredoxin domain
NLLIHHGE_01976 0.0 M LPXTG-motif cell wall anchor domain protein
NLLIHHGE_01979 1.6e-126 O Bacterial dnaA protein
NLLIHHGE_01980 2.6e-217 L Integrase core domain
NLLIHHGE_01981 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLLIHHGE_01982 1.1e-309 lmrA V ABC transporter, ATP-binding protein
NLLIHHGE_01983 0.0 yfiC V ABC transporter
NLLIHHGE_01984 4.9e-284 pipD E Dipeptidase
NLLIHHGE_01985 4.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NLLIHHGE_01986 4e-133 gntR K UbiC transcription regulator-associated domain protein
NLLIHHGE_01987 1.9e-126 I transferase activity, transferring acyl groups other than amino-acyl groups
NLLIHHGE_01988 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NLLIHHGE_01989 2.7e-244 yagE E amino acid
NLLIHHGE_01990 1.3e-139 aroD S Serine hydrolase (FSH1)
NLLIHHGE_01991 1.3e-241 brnQ U Component of the transport system for branched-chain amino acids
NLLIHHGE_01992 1.1e-167 GK ROK family
NLLIHHGE_01993 0.0 tetP J elongation factor G
NLLIHHGE_01994 5.1e-81 uspA T universal stress protein
NLLIHHGE_01995 1.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
NLLIHHGE_01996 1.3e-61
NLLIHHGE_01997 5.2e-14
NLLIHHGE_01998 4.3e-108
NLLIHHGE_01999 3e-135 V ABC transporter
NLLIHHGE_02000 2.4e-212 EGP Major facilitator Superfamily
NLLIHHGE_02001 5e-257 G PTS system Galactitol-specific IIC component
NLLIHHGE_02002 2.4e-181 1.6.5.5 C Zinc-binding dehydrogenase
NLLIHHGE_02003 6.3e-162
NLLIHHGE_02004 1e-72 K Transcriptional regulator
NLLIHHGE_02005 2.2e-185 D Alpha beta
NLLIHHGE_02006 8.4e-52 ypaA S Protein of unknown function (DUF1304)
NLLIHHGE_02007 0.0 yjcE P Sodium proton antiporter
NLLIHHGE_02008 1.6e-52 yvlA
NLLIHHGE_02009 1.3e-114 P Cobalt transport protein
NLLIHHGE_02010 6.4e-249 cbiO1 S ABC transporter, ATP-binding protein
NLLIHHGE_02011 1.9e-95 S ABC-type cobalt transport system, permease component
NLLIHHGE_02012 3.3e-133 S membrane transporter protein
NLLIHHGE_02013 2.5e-138 IQ KR domain
NLLIHHGE_02014 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
NLLIHHGE_02015 2.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NLLIHHGE_02016 5.3e-85 S Double zinc ribbon
NLLIHHGE_02017 1.4e-139 T GHKL domain
NLLIHHGE_02018 5.4e-130 agrA K LytTr DNA-binding domain
NLLIHHGE_02019 1.9e-19 S Domain of unknown function (DUF4767)
NLLIHHGE_02020 1.6e-24 D nuclear chromosome segregation
NLLIHHGE_02021 3.1e-09
NLLIHHGE_02022 5.8e-118
NLLIHHGE_02024 8.9e-09 S Domain of unknown function (DUF5067)
NLLIHHGE_02025 7.1e-24 S Domain of unknown function (DUF4767)
NLLIHHGE_02027 1.8e-151 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NLLIHHGE_02028 1.9e-33 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NLLIHHGE_02029 2.1e-115 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NLLIHHGE_02030 2.2e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NLLIHHGE_02031 4.7e-255 yagE E amino acid
NLLIHHGE_02032 2.6e-85 dps P Belongs to the Dps family
NLLIHHGE_02033 0.0 pacL 3.6.3.8 P P-type ATPase
NLLIHHGE_02034 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NLLIHHGE_02035 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NLLIHHGE_02036 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NLLIHHGE_02037 1.3e-145 potB P ABC transporter permease
NLLIHHGE_02038 4.9e-140 potC P ABC transporter permease
NLLIHHGE_02039 3.3e-208 potD P ABC transporter
NLLIHHGE_02040 6.2e-230
NLLIHHGE_02041 3.6e-233 EGP Sugar (and other) transporter
NLLIHHGE_02042 7.9e-255 yfnA E Amino Acid
NLLIHHGE_02043 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NLLIHHGE_02044 3.8e-102 gmk2 2.7.4.8 F Guanylate kinase
NLLIHHGE_02045 1.5e-82 zur P Belongs to the Fur family
NLLIHHGE_02046 1.2e-16 3.2.1.14 GH18
NLLIHHGE_02047 4.9e-151
NLLIHHGE_02048 4.4e-39 pspC KT PspC domain protein
NLLIHHGE_02049 1.6e-94 K Transcriptional regulator (TetR family)
NLLIHHGE_02050 1.5e-220 V domain protein
NLLIHHGE_02051 2.7e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NLLIHHGE_02053 2e-31 S Transglycosylase associated protein
NLLIHHGE_02054 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NLLIHHGE_02055 5.5e-126 3.1.3.73 G phosphoglycerate mutase
NLLIHHGE_02056 6.8e-116 dedA S SNARE associated Golgi protein
NLLIHHGE_02057 0.0 helD 3.6.4.12 L DNA helicase
NLLIHHGE_02058 1e-243 nox C NADH oxidase
NLLIHHGE_02059 5.9e-255 nox C NADH oxidase
NLLIHHGE_02060 9.2e-161 EG EamA-like transporter family
NLLIHHGE_02061 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NLLIHHGE_02062 7.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NLLIHHGE_02063 1.3e-221 S cog cog1373
NLLIHHGE_02065 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NLLIHHGE_02066 2.8e-219 oxlT P Major Facilitator Superfamily
NLLIHHGE_02067 1.6e-157 spoU 2.1.1.185 J Methyltransferase
NLLIHHGE_02068 2.3e-66 rmeB K transcriptional regulator, MerR family
NLLIHHGE_02069 2.7e-117 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
NLLIHHGE_02070 2.9e-51 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NLLIHHGE_02071 1.2e-99 crp_2 K Cyclic nucleotide-binding domain
NLLIHHGE_02072 1.3e-128 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
NLLIHHGE_02073 9.1e-138 pnuC H nicotinamide mononucleotide transporter
NLLIHHGE_02074 8.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NLLIHHGE_02075 6.1e-100 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NLLIHHGE_02076 4.3e-98 ywlG S Belongs to the UPF0340 family
NLLIHHGE_02077 4.5e-195 EGP Major facilitator Superfamily
NLLIHHGE_02078 3.9e-121 M Lysin motif
NLLIHHGE_02079 1.6e-79
NLLIHHGE_02080 2.3e-165 P CorA-like Mg2+ transporter protein
NLLIHHGE_02081 3.1e-95 wecD3 K PFAM GCN5-related N-acetyltransferase
NLLIHHGE_02082 4e-100 ltrA S Bacterial low temperature requirement A protein (LtrA)
NLLIHHGE_02083 2.7e-200 cytX U Belongs to the purine-cytosine permease (2.A.39) family
NLLIHHGE_02084 4.3e-13
NLLIHHGE_02085 9.4e-77 S Domain of unknown function (DUF4767)
NLLIHHGE_02089 1.3e-270 pipD E Dipeptidase
NLLIHHGE_02090 0.0 yjbQ P TrkA C-terminal domain protein
NLLIHHGE_02091 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NLLIHHGE_02092 5.3e-289 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NLLIHHGE_02093 9.9e-83
NLLIHHGE_02094 2.5e-36
NLLIHHGE_02095 4.9e-102 K DNA-templated transcription, initiation
NLLIHHGE_02096 1.7e-128
NLLIHHGE_02097 5.1e-66 K Transcriptional regulator, HxlR family
NLLIHHGE_02098 9.5e-162 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NLLIHHGE_02099 3.7e-133 epsB M biosynthesis protein
NLLIHHGE_02100 1.3e-115 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NLLIHHGE_02101 3.4e-137 cps2D 5.1.3.2 M RmlD substrate binding domain
NLLIHHGE_02102 8.8e-84 tuaA M Bacterial sugar transferase
NLLIHHGE_02103 5.2e-76 lsgF M Glycosyl transferase family 2
NLLIHHGE_02104 1.3e-42 M Glycosyl transferases group 1
NLLIHHGE_02105 4.2e-58 S Glycosyltransferase like family 2
NLLIHHGE_02106 9e-62 M Glycosyltransferase sugar-binding region containing DXD motif
NLLIHHGE_02107 4.4e-34 M Glycosyltransferase like family 2
NLLIHHGE_02109 1.4e-41 S Polysaccharide pyruvyl transferase
NLLIHHGE_02110 5.5e-123 cps2J S Polysaccharide biosynthesis protein
NLLIHHGE_02111 1e-10 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
NLLIHHGE_02112 6.4e-63 S Core-2/I-Branching enzyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)