ORF_ID e_value Gene_name EC_number CAZy COGs Description
PAKAOEHF_00001 2.5e-29 L PFAM transposase IS200-family protein
PAKAOEHF_00004 7.8e-24
PAKAOEHF_00005 4e-75
PAKAOEHF_00006 1.1e-30
PAKAOEHF_00007 9.4e-141 3.1.3.73 G Belongs to the phosphoglycerate mutase family
PAKAOEHF_00008 3.9e-125 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PAKAOEHF_00009 9.8e-103 fic D Fic/DOC family
PAKAOEHF_00010 1.3e-70
PAKAOEHF_00011 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
PAKAOEHF_00012 2.7e-91 L nuclease
PAKAOEHF_00013 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PAKAOEHF_00014 1.5e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PAKAOEHF_00015 2.5e-177 M Glycosyl hydrolases family 25
PAKAOEHF_00016 1.8e-144 ywqE 3.1.3.48 GM PHP domain protein
PAKAOEHF_00018 4e-37
PAKAOEHF_00019 1.5e-67 T Toxin-antitoxin system, toxin component, MazF family
PAKAOEHF_00021 3.4e-250 mmuP E amino acid
PAKAOEHF_00022 8.9e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
PAKAOEHF_00023 5.3e-283 2.4.1.5 GH13 G Glycosyl hydrolase family 70
PAKAOEHF_00024 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
PAKAOEHF_00025 0.0 ganB 3.2.1.89 G arabinogalactan
PAKAOEHF_00026 1.8e-24 S Acyltransferase family
PAKAOEHF_00028 4.6e-48 S Glycosyltransferase like family 2
PAKAOEHF_00029 1.3e-30 S COG0463 Glycosyltransferases involved in cell wall biogenesis
PAKAOEHF_00030 2.7e-31 2.7.8.12 M Glycosyltransferase, group 2 family protein
PAKAOEHF_00031 1.7e-30 M Glycosyltransferase sugar-binding region containing DXD motif
PAKAOEHF_00032 4.8e-72 cps2I S Psort location CytoplasmicMembrane, score
PAKAOEHF_00034 3.6e-38 GT2,GT4 M Glycosyltransferase GT-D fold
PAKAOEHF_00035 4e-67 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
PAKAOEHF_00036 7e-87 GT4 G Glycosyl transferase 4-like
PAKAOEHF_00037 4.2e-48 pglC M Bacterial sugar transferase
PAKAOEHF_00038 3.1e-104 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PAKAOEHF_00039 5.2e-99 epsB M biosynthesis protein
PAKAOEHF_00052 8.4e-30 L PFAM transposase IS200-family protein
PAKAOEHF_00053 3.3e-129 narI 1.7.5.1 C Nitrate reductase
PAKAOEHF_00054 2.5e-98 narJ C nitrate reductase molybdenum cofactor assembly chaperone
PAKAOEHF_00055 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
PAKAOEHF_00056 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PAKAOEHF_00057 5.7e-186 moeB 2.7.7.73, 2.7.7.80 H ThiF family
PAKAOEHF_00058 1.2e-83 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PAKAOEHF_00059 3.3e-225 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
PAKAOEHF_00060 7.5e-75 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PAKAOEHF_00061 7.6e-95 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PAKAOEHF_00062 6.3e-42
PAKAOEHF_00063 8e-183 comP 2.7.13.3 F Sensor histidine kinase
PAKAOEHF_00064 4.9e-114 nreC K PFAM regulatory protein LuxR
PAKAOEHF_00065 3.6e-18
PAKAOEHF_00066 1.8e-173
PAKAOEHF_00067 3.7e-144 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
PAKAOEHF_00068 1.5e-217 narK P Transporter, major facilitator family protein
PAKAOEHF_00069 1.1e-31 moaD 2.8.1.12 H ThiS family
PAKAOEHF_00070 9.1e-63 moaE 2.8.1.12 H MoaE protein
PAKAOEHF_00071 3.5e-79 S Flavodoxin
PAKAOEHF_00072 1e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PAKAOEHF_00073 1.7e-126 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
PAKAOEHF_00074 4.5e-175 fecB P Periplasmic binding protein
PAKAOEHF_00075 5e-176
PAKAOEHF_00076 2.5e-74
PAKAOEHF_00077 6.9e-13 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
PAKAOEHF_00078 1.7e-87 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
PAKAOEHF_00079 0.0 S SEC-C Motif Domain Protein
PAKAOEHF_00080 1.2e-51
PAKAOEHF_00081 7.5e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PAKAOEHF_00082 1.9e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PAKAOEHF_00083 1.4e-116 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PAKAOEHF_00084 2.7e-230 clcA_2 P Chloride transporter, ClC family
PAKAOEHF_00085 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
PAKAOEHF_00086 5.8e-112 lssY 3.6.1.27 I Acid phosphatase homologues
PAKAOEHF_00089 5.5e-69 K Bacterial transcriptional regulator
PAKAOEHF_00090 5.5e-161 K LysR substrate binding domain protein
PAKAOEHF_00091 1.5e-83 C Flavodoxin
PAKAOEHF_00092 3.8e-80 yphH S Cupin domain
PAKAOEHF_00093 4.5e-74 yeaL S UPF0756 membrane protein
PAKAOEHF_00094 1.2e-242 EGP Major facilitator Superfamily
PAKAOEHF_00095 1.9e-74 copY K Copper transport repressor CopY TcrY
PAKAOEHF_00096 8.5e-246 yhdP S Transporter associated domain
PAKAOEHF_00097 0.0 ubiB S ABC1 family
PAKAOEHF_00098 2.8e-143 S DUF218 domain
PAKAOEHF_00099 4.1e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PAKAOEHF_00100 2.4e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAKAOEHF_00101 4.5e-55 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAKAOEHF_00102 0.0 uvrA3 L excinuclease ABC, A subunit
PAKAOEHF_00103 5.1e-122 S SNARE associated Golgi protein
PAKAOEHF_00104 1.3e-229 N Uncharacterized conserved protein (DUF2075)
PAKAOEHF_00105 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PAKAOEHF_00107 5.1e-254 yifK E Amino acid permease
PAKAOEHF_00108 6.5e-151 endA V DNA/RNA non-specific endonuclease
PAKAOEHF_00109 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAKAOEHF_00110 3.5e-42 ybaN S Protein of unknown function (DUF454)
PAKAOEHF_00111 4.1e-72 S Protein of unknown function (DUF3290)
PAKAOEHF_00112 1.2e-112 yviA S Protein of unknown function (DUF421)
PAKAOEHF_00113 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
PAKAOEHF_00114 7e-19
PAKAOEHF_00115 4e-89 ntd 2.4.2.6 F Nucleoside
PAKAOEHF_00116 4.8e-151 3.1.3.102, 3.1.3.104 S hydrolase
PAKAOEHF_00117 6.8e-49 yrvD S Pfam:DUF1049
PAKAOEHF_00119 1.9e-08
PAKAOEHF_00122 2.9e-30 L PFAM transposase IS200-family protein
PAKAOEHF_00126 2.3e-129 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PAKAOEHF_00127 1.1e-134 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PAKAOEHF_00128 8.1e-218 uxaC 5.3.1.12 G glucuronate isomerase
PAKAOEHF_00129 1.2e-214 uxuT G MFS/sugar transport protein
PAKAOEHF_00130 4.4e-181 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
PAKAOEHF_00131 1.1e-210 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
PAKAOEHF_00132 1.5e-52 kdgR K FCD domain
PAKAOEHF_00133 2.1e-124 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
PAKAOEHF_00134 9.3e-161 uxaA 4.2.1.7, 4.4.1.24 G Altronate
PAKAOEHF_00135 1.8e-68 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
PAKAOEHF_00136 4.3e-126 uxaA 4.2.1.7, 4.4.1.24 G Altronate
PAKAOEHF_00137 6.3e-151 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
PAKAOEHF_00139 1.2e-94 S module of peptide synthetase
PAKAOEHF_00140 3.6e-226 uxaC 5.3.1.12 G glucuronate isomerase
PAKAOEHF_00141 1.4e-220 yjmB G MFS/sugar transport protein
PAKAOEHF_00142 2.7e-95 exuR K Periplasmic binding protein domain
PAKAOEHF_00143 5.5e-169 1.1.1.346 C Aldo keto reductase
PAKAOEHF_00144 2.1e-39 gcvR T Belongs to the UPF0237 family
PAKAOEHF_00145 8.7e-243 XK27_08635 S UPF0210 protein
PAKAOEHF_00146 2.4e-95 K Acetyltransferase (GNAT) domain
PAKAOEHF_00147 3.4e-160 S Alpha beta hydrolase
PAKAOEHF_00148 8.4e-159 gspA M family 8
PAKAOEHF_00149 2.3e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PAKAOEHF_00150 7.6e-94
PAKAOEHF_00151 6.4e-162 degV S EDD domain protein, DegV family
PAKAOEHF_00152 0.0 FbpA K Fibronectin-binding protein
PAKAOEHF_00153 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PAKAOEHF_00154 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
PAKAOEHF_00155 3.1e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PAKAOEHF_00156 2.2e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PAKAOEHF_00157 1.5e-65 esbA S Family of unknown function (DUF5322)
PAKAOEHF_00158 1.7e-69 rnhA 3.1.26.4 L Ribonuclease HI
PAKAOEHF_00159 1e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PAKAOEHF_00160 3.2e-83 F Belongs to the NrdI family
PAKAOEHF_00161 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PAKAOEHF_00162 8.9e-104 ypsA S Belongs to the UPF0398 family
PAKAOEHF_00163 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PAKAOEHF_00164 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PAKAOEHF_00165 1.4e-162 EG EamA-like transporter family
PAKAOEHF_00166 7.3e-124 dnaD L DnaD domain protein
PAKAOEHF_00167 2.9e-85 ypmB S Protein conserved in bacteria
PAKAOEHF_00168 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PAKAOEHF_00169 2e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PAKAOEHF_00170 4.2e-162 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PAKAOEHF_00171 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PAKAOEHF_00172 3.8e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PAKAOEHF_00173 3.8e-87 S Protein of unknown function (DUF1440)
PAKAOEHF_00174 0.0 rafA 3.2.1.22 G alpha-galactosidase
PAKAOEHF_00175 2.3e-187 galR K Periplasmic binding protein-like domain
PAKAOEHF_00176 1.7e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PAKAOEHF_00177 6.4e-179 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PAKAOEHF_00178 2.6e-124 lrgB M LrgB-like family
PAKAOEHF_00179 1.9e-66 lrgA S LrgA family
PAKAOEHF_00180 1.6e-129 lytT K response regulator receiver
PAKAOEHF_00181 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
PAKAOEHF_00182 4e-148 f42a O Band 7 protein
PAKAOEHF_00183 3.6e-260 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PAKAOEHF_00184 5.8e-157 yitU 3.1.3.104 S hydrolase
PAKAOEHF_00185 9.2e-39 S Cytochrome B5
PAKAOEHF_00186 4.9e-114 nreC K PFAM regulatory protein LuxR
PAKAOEHF_00187 4.2e-161 hipB K Helix-turn-helix
PAKAOEHF_00188 2.8e-57 yitW S Iron-sulfur cluster assembly protein
PAKAOEHF_00189 2.3e-270 sufB O assembly protein SufB
PAKAOEHF_00190 1.2e-79 nifU C SUF system FeS assembly protein, NifU family
PAKAOEHF_00191 2.3e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PAKAOEHF_00192 2.5e-239 sufD O FeS assembly protein SufD
PAKAOEHF_00193 6.5e-145 sufC O FeS assembly ATPase SufC
PAKAOEHF_00194 1.2e-31 feoA P FeoA domain
PAKAOEHF_00195 1.7e-196 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PAKAOEHF_00196 2.6e-158 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PAKAOEHF_00197 2.5e-272 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PAKAOEHF_00198 2.9e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PAKAOEHF_00199 8.5e-63 ydiI Q Thioesterase superfamily
PAKAOEHF_00200 2.4e-109 yvrI K sigma factor activity
PAKAOEHF_00201 5e-202 G Transporter, major facilitator family protein
PAKAOEHF_00202 0.0 S Bacterial membrane protein YfhO
PAKAOEHF_00203 1.5e-103 T Ion transport 2 domain protein
PAKAOEHF_00204 8.8e-78 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PAKAOEHF_00205 8e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
PAKAOEHF_00206 9.7e-93 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
PAKAOEHF_00207 5.3e-195 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PAKAOEHF_00208 5.6e-180 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PAKAOEHF_00210 0.0 L PLD-like domain
PAKAOEHF_00211 2.1e-20
PAKAOEHF_00212 9.1e-34 higA K addiction module antidote protein HigA
PAKAOEHF_00214 1e-20 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
PAKAOEHF_00215 7e-10 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
PAKAOEHF_00216 6.1e-80 K Putative DNA-binding domain
PAKAOEHF_00218 1.1e-08 L restriction endonuclease
PAKAOEHF_00219 8.4e-111 3.1.21.3 L Type I restriction modification DNA specificity domain
PAKAOEHF_00220 2.6e-217 L Integrase core domain
PAKAOEHF_00221 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_00222 2.6e-217 L Integrase core domain
PAKAOEHF_00223 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_00224 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PAKAOEHF_00225 2.6e-217 L Integrase core domain
PAKAOEHF_00226 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_00227 6.5e-153 L Transposase IS66 family
PAKAOEHF_00228 2.2e-37 XK27_01125 L PFAM IS66 Orf2 family protein
PAKAOEHF_00229 2.6e-217 L Integrase core domain
PAKAOEHF_00230 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_00233 2.7e-206 2.7.13.3 T GHKL domain
PAKAOEHF_00234 1e-118 K LytTr DNA-binding domain
PAKAOEHF_00235 1e-24
PAKAOEHF_00236 7.6e-20 relB L Addiction module antitoxin, RelB DinJ family
PAKAOEHF_00237 6.3e-90 XK27_08850 J Aminoacyl-tRNA editing domain
PAKAOEHF_00238 1e-56 yphI 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PAKAOEHF_00239 2.2e-193 V Beta-lactamase
PAKAOEHF_00240 3.2e-95 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PAKAOEHF_00241 1.2e-123 yhiD S MgtC family
PAKAOEHF_00242 6.7e-110 S GyrI-like small molecule binding domain
PAKAOEHF_00244 8.3e-122 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
PAKAOEHF_00245 4.2e-50 azlD E Branched-chain amino acid transport
PAKAOEHF_00246 3.1e-119 azlC E azaleucine resistance protein AzlC
PAKAOEHF_00247 6.5e-257 K Aminotransferase class I and II
PAKAOEHF_00248 2e-299 S amidohydrolase
PAKAOEHF_00249 1.6e-125 S Alpha/beta hydrolase of unknown function (DUF915)
PAKAOEHF_00250 6e-148 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKAOEHF_00252 1.8e-161 S reductase
PAKAOEHF_00253 4.1e-89 2.3.1.183 M Acetyltransferase GNAT family
PAKAOEHF_00254 3.8e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PAKAOEHF_00255 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
PAKAOEHF_00256 1.1e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PAKAOEHF_00257 0.0 asnB 6.3.5.4 E Asparagine synthase
PAKAOEHF_00258 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PAKAOEHF_00259 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PAKAOEHF_00260 2.7e-132 jag S R3H domain protein
PAKAOEHF_00261 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PAKAOEHF_00262 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PAKAOEHF_00263 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PAKAOEHF_00264 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PAKAOEHF_00265 1.5e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PAKAOEHF_00266 7.4e-125 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
PAKAOEHF_00267 1.7e-34 yaaA S S4 domain protein YaaA
PAKAOEHF_00268 4.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PAKAOEHF_00269 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAKAOEHF_00270 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PAKAOEHF_00271 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
PAKAOEHF_00272 2.2e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PAKAOEHF_00273 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PAKAOEHF_00274 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PAKAOEHF_00275 2e-74 rplI J Binds to the 23S rRNA
PAKAOEHF_00276 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PAKAOEHF_00277 8.4e-205 yttB EGP Major facilitator Superfamily
PAKAOEHF_00278 8.5e-59
PAKAOEHF_00279 4.3e-158 S Polyphosphate nucleotide phosphotransferase, PPK2 family
PAKAOEHF_00280 1.9e-74 K DNA-binding helix-turn-helix protein
PAKAOEHF_00282 1.2e-73 K helix_turn_helix multiple antibiotic resistance protein
PAKAOEHF_00283 4.8e-311 lmrA 3.6.3.44 V ABC transporter
PAKAOEHF_00285 3.1e-130 K response regulator
PAKAOEHF_00286 0.0 vicK 2.7.13.3 T Histidine kinase
PAKAOEHF_00287 6e-249 yycH S YycH protein
PAKAOEHF_00288 8.4e-151 yycI S YycH protein
PAKAOEHF_00289 4.5e-154 vicX 3.1.26.11 S domain protein
PAKAOEHF_00290 1.2e-217 htrA 3.4.21.107 O serine protease
PAKAOEHF_00291 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PAKAOEHF_00292 3.6e-177 ABC-SBP S ABC transporter
PAKAOEHF_00293 1e-87 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PAKAOEHF_00295 2.4e-95 S reductase
PAKAOEHF_00296 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
PAKAOEHF_00297 7.5e-155 glcU U sugar transport
PAKAOEHF_00298 2.7e-148 E Glyoxalase-like domain
PAKAOEHF_00299 1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAKAOEHF_00300 4.9e-257 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PAKAOEHF_00301 4.4e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PAKAOEHF_00302 2.2e-128 V ABC transporter
PAKAOEHF_00303 2.1e-214 bacI V MacB-like periplasmic core domain
PAKAOEHF_00304 8.1e-32
PAKAOEHF_00305 3.4e-258 S Putative peptidoglycan binding domain
PAKAOEHF_00307 8.7e-54 L An automated process has identified a potential problem with this gene model
PAKAOEHF_00308 2.5e-86 K FR47-like protein
PAKAOEHF_00309 1.1e-121 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PAKAOEHF_00311 5e-75 osmC O OsmC-like protein
PAKAOEHF_00312 3.7e-174 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAKAOEHF_00313 2e-219 patA 2.6.1.1 E Aminotransferase
PAKAOEHF_00314 2.7e-32
PAKAOEHF_00315 0.0 clpL O associated with various cellular activities
PAKAOEHF_00316 2.2e-156 L hmm pf00665
PAKAOEHF_00317 2.2e-128 L Helix-turn-helix domain
PAKAOEHF_00318 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PAKAOEHF_00319 1.3e-153
PAKAOEHF_00320 5.1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PAKAOEHF_00321 2.5e-244 purD 6.3.4.13 F Belongs to the GARS family
PAKAOEHF_00322 1e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PAKAOEHF_00323 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PAKAOEHF_00324 5.8e-194 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PAKAOEHF_00325 4e-278 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PAKAOEHF_00326 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAKAOEHF_00327 8.9e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAKAOEHF_00328 1.3e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PAKAOEHF_00329 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PAKAOEHF_00330 2.4e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PAKAOEHF_00331 2.3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PAKAOEHF_00332 1.6e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PAKAOEHF_00333 1.5e-132 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PAKAOEHF_00334 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PAKAOEHF_00335 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PAKAOEHF_00336 4.7e-172 K AI-2E family transporter
PAKAOEHF_00337 7.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PAKAOEHF_00338 5.3e-113 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
PAKAOEHF_00339 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PAKAOEHF_00340 1.3e-128 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PAKAOEHF_00341 2.5e-172 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PAKAOEHF_00342 1.1e-247 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PAKAOEHF_00343 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PAKAOEHF_00344 1.5e-139 K LysR substrate binding domain
PAKAOEHF_00345 3.6e-52 azlD S branched-chain amino acid
PAKAOEHF_00346 1.9e-140 azlC E AzlC protein
PAKAOEHF_00347 3.7e-202 hpk31 2.7.13.3 T Histidine kinase
PAKAOEHF_00348 3.8e-125 K response regulator
PAKAOEHF_00349 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PAKAOEHF_00350 1.6e-171 deoR K sugar-binding domain protein
PAKAOEHF_00351 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PAKAOEHF_00352 2.6e-236 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
PAKAOEHF_00353 4.1e-236 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PAKAOEHF_00354 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PAKAOEHF_00355 3.1e-136 XK27_01040 S Protein of unknown function (DUF1129)
PAKAOEHF_00356 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PAKAOEHF_00357 2e-31 yyzM S Bacterial protein of unknown function (DUF951)
PAKAOEHF_00358 8.5e-154 spo0J K Belongs to the ParB family
PAKAOEHF_00359 3.6e-140 soj D Sporulation initiation inhibitor
PAKAOEHF_00360 2.5e-146 noc K Belongs to the ParB family
PAKAOEHF_00361 1.2e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PAKAOEHF_00362 1.9e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
PAKAOEHF_00363 6.6e-170 rihC 3.2.2.1 F Nucleoside
PAKAOEHF_00364 1e-218 nupG F Nucleoside transporter
PAKAOEHF_00365 1.5e-221 cycA E Amino acid permease
PAKAOEHF_00366 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKAOEHF_00367 1.8e-265 glnP P ABC transporter
PAKAOEHF_00368 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PAKAOEHF_00369 3.3e-221 UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_00370 4.6e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
PAKAOEHF_00371 2.2e-236 lmrB EGP Major facilitator Superfamily
PAKAOEHF_00372 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PAKAOEHF_00373 9e-112 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PAKAOEHF_00374 3.6e-160 sufD O Uncharacterized protein family (UPF0051)
PAKAOEHF_00375 1.6e-42 lytE M LysM domain protein
PAKAOEHF_00376 0.0 oppD EP Psort location Cytoplasmic, score
PAKAOEHF_00377 1.1e-87 lytE M LysM domain protein
PAKAOEHF_00378 7.1e-149 xth 3.1.11.2 L exodeoxyribonuclease III
PAKAOEHF_00379 9.5e-236 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PAKAOEHF_00380 2e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
PAKAOEHF_00381 1.5e-152 yeaE S Aldo keto
PAKAOEHF_00382 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
PAKAOEHF_00383 1.8e-284 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
PAKAOEHF_00384 4.5e-79 S Psort location Cytoplasmic, score
PAKAOEHF_00385 7.7e-86 S Short repeat of unknown function (DUF308)
PAKAOEHF_00386 1e-23
PAKAOEHF_00387 8.2e-102 V VanZ like family
PAKAOEHF_00388 8.2e-233 cycA E Amino acid permease
PAKAOEHF_00389 4.3e-85 perR P Belongs to the Fur family
PAKAOEHF_00390 2.4e-259 EGP Major facilitator Superfamily
PAKAOEHF_00391 7.9e-94 tag 3.2.2.20 L glycosylase
PAKAOEHF_00392 1.6e-216 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PAKAOEHF_00393 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PAKAOEHF_00394 1.7e-41
PAKAOEHF_00395 3e-301 ytgP S Polysaccharide biosynthesis protein
PAKAOEHF_00396 1.6e-152 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PAKAOEHF_00397 4.8e-276 pepV 3.5.1.18 E dipeptidase PepV
PAKAOEHF_00398 1.9e-86 uspA T Belongs to the universal stress protein A family
PAKAOEHF_00399 5.7e-178 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PAKAOEHF_00400 1.5e-115 dck 2.7.1.74 F deoxynucleoside kinase
PAKAOEHF_00401 7.2e-112
PAKAOEHF_00402 4.8e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
PAKAOEHF_00403 1.8e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAKAOEHF_00404 2.1e-32
PAKAOEHF_00405 1.2e-118 S CAAX protease self-immunity
PAKAOEHF_00406 1.9e-43
PAKAOEHF_00408 1.2e-25
PAKAOEHF_00409 5.9e-24
PAKAOEHF_00410 1.3e-142 S Domain of unknown function DUF1829
PAKAOEHF_00411 3.6e-72
PAKAOEHF_00412 5.3e-56 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PAKAOEHF_00413 7e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
PAKAOEHF_00414 6.2e-105 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
PAKAOEHF_00415 5.1e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PAKAOEHF_00416 9.1e-104 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
PAKAOEHF_00417 2.3e-215 folP 2.5.1.15 H dihydropteroate synthase
PAKAOEHF_00418 1e-43
PAKAOEHF_00419 3.3e-40
PAKAOEHF_00421 1.1e-167 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PAKAOEHF_00422 2.8e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PAKAOEHF_00423 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PAKAOEHF_00424 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PAKAOEHF_00425 9.4e-38 yheA S Belongs to the UPF0342 family
PAKAOEHF_00426 2.2e-218 yhaO L Ser Thr phosphatase family protein
PAKAOEHF_00427 0.0 L AAA domain
PAKAOEHF_00428 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PAKAOEHF_00430 8.3e-78 hit FG histidine triad
PAKAOEHF_00431 3.9e-136 ecsA V ABC transporter, ATP-binding protein
PAKAOEHF_00432 4.3e-217 ecsB U ABC transporter
PAKAOEHF_00433 8.1e-122 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PAKAOEHF_00434 0.0 2.7.7.7, 3.4.21.110 D Leucine-rich repeat (LRR) protein
PAKAOEHF_00435 1.8e-260 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PAKAOEHF_00436 4.3e-183 iolS C Aldo keto reductase
PAKAOEHF_00437 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
PAKAOEHF_00438 7.5e-58 ytzB S Small secreted protein
PAKAOEHF_00439 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PAKAOEHF_00440 2.7e-117 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PAKAOEHF_00441 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PAKAOEHF_00442 1.9e-119 ybhL S Belongs to the BI1 family
PAKAOEHF_00443 8.3e-117 yoaK S Protein of unknown function (DUF1275)
PAKAOEHF_00444 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PAKAOEHF_00445 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PAKAOEHF_00446 3e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PAKAOEHF_00447 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PAKAOEHF_00448 4.4e-226 dnaB L replication initiation and membrane attachment
PAKAOEHF_00449 2.4e-170 dnaI L Primosomal protein DnaI
PAKAOEHF_00450 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PAKAOEHF_00451 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PAKAOEHF_00452 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PAKAOEHF_00453 1.3e-96 yqeG S HAD phosphatase, family IIIA
PAKAOEHF_00454 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
PAKAOEHF_00455 1.9e-47 yhbY J RNA-binding protein
PAKAOEHF_00456 6.7e-124 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PAKAOEHF_00457 3.5e-114 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PAKAOEHF_00458 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PAKAOEHF_00459 1.7e-139 yqeM Q Methyltransferase
PAKAOEHF_00460 5.1e-212 ylbM S Belongs to the UPF0348 family
PAKAOEHF_00461 2.9e-99 yceD S Uncharacterized ACR, COG1399
PAKAOEHF_00462 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PAKAOEHF_00463 1.5e-121 K response regulator
PAKAOEHF_00464 4.1e-278 arlS 2.7.13.3 T Histidine kinase
PAKAOEHF_00465 4.3e-267 yjeM E Amino Acid
PAKAOEHF_00466 8.3e-230 V MatE
PAKAOEHF_00467 7.4e-68 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PAKAOEHF_00468 2.9e-168 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PAKAOEHF_00469 1e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PAKAOEHF_00470 4.8e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAKAOEHF_00471 5.3e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PAKAOEHF_00472 6.7e-59 yodB K Transcriptional regulator, HxlR family
PAKAOEHF_00473 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PAKAOEHF_00474 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PAKAOEHF_00475 3e-116 rlpA M PFAM NLP P60 protein
PAKAOEHF_00476 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
PAKAOEHF_00477 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PAKAOEHF_00478 2.6e-70 yneR S Belongs to the HesB IscA family
PAKAOEHF_00479 0.0 S membrane
PAKAOEHF_00480 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PAKAOEHF_00481 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PAKAOEHF_00482 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PAKAOEHF_00483 2.4e-113 gluP 3.4.21.105 S Peptidase, S54 family
PAKAOEHF_00484 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
PAKAOEHF_00485 1.5e-183 glk 2.7.1.2 G Glucokinase
PAKAOEHF_00486 3.4e-67 yqhL P Rhodanese-like protein
PAKAOEHF_00487 5.9e-22 S Protein of unknown function (DUF3042)
PAKAOEHF_00488 3.1e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PAKAOEHF_00489 1.4e-264 glnA 6.3.1.2 E glutamine synthetase
PAKAOEHF_00490 1.2e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PAKAOEHF_00491 1.1e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PAKAOEHF_00492 3.9e-12
PAKAOEHF_00493 3.3e-155 P Belongs to the nlpA lipoprotein family
PAKAOEHF_00494 1.6e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PAKAOEHF_00495 1.4e-50 S Iron-sulfur cluster assembly protein
PAKAOEHF_00496 1e-151
PAKAOEHF_00497 4.4e-178
PAKAOEHF_00498 2.5e-89 dut S Protein conserved in bacteria
PAKAOEHF_00501 2.6e-112 K Transcriptional regulator
PAKAOEHF_00502 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
PAKAOEHF_00503 7.4e-55 ysxB J Cysteine protease Prp
PAKAOEHF_00504 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PAKAOEHF_00505 2.4e-130 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PAKAOEHF_00506 2.4e-203 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PAKAOEHF_00507 1.6e-115 J 2'-5' RNA ligase superfamily
PAKAOEHF_00508 2.2e-70 yqhY S Asp23 family, cell envelope-related function
PAKAOEHF_00509 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PAKAOEHF_00510 2.7e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PAKAOEHF_00511 1.5e-223 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PAKAOEHF_00512 2.5e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PAKAOEHF_00513 1.3e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PAKAOEHF_00514 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PAKAOEHF_00515 3.3e-77 argR K Regulates arginine biosynthesis genes
PAKAOEHF_00516 3.3e-263 recN L May be involved in recombinational repair of damaged DNA
PAKAOEHF_00517 1.7e-54
PAKAOEHF_00518 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PAKAOEHF_00519 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PAKAOEHF_00520 2.4e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PAKAOEHF_00521 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PAKAOEHF_00522 3.6e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PAKAOEHF_00523 2.8e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PAKAOEHF_00524 2.9e-131 stp 3.1.3.16 T phosphatase
PAKAOEHF_00525 0.0 KLT serine threonine protein kinase
PAKAOEHF_00526 5.3e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PAKAOEHF_00527 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PAKAOEHF_00528 5.3e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
PAKAOEHF_00529 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PAKAOEHF_00530 4.7e-58 asp S Asp23 family, cell envelope-related function
PAKAOEHF_00531 0.0 yloV S DAK2 domain fusion protein YloV
PAKAOEHF_00532 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PAKAOEHF_00533 2.1e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PAKAOEHF_00534 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAKAOEHF_00535 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PAKAOEHF_00536 0.0 smc D Required for chromosome condensation and partitioning
PAKAOEHF_00537 1.8e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PAKAOEHF_00538 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PAKAOEHF_00539 1e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PAKAOEHF_00540 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PAKAOEHF_00541 4.1e-40 ylqC S Belongs to the UPF0109 family
PAKAOEHF_00542 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PAKAOEHF_00543 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PAKAOEHF_00544 1.3e-260 yfnA E amino acid
PAKAOEHF_00545 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PAKAOEHF_00546 1.7e-34
PAKAOEHF_00547 3.5e-52 S Mazg nucleotide pyrophosphohydrolase
PAKAOEHF_00548 3.3e-160 xth 3.1.11.2 L exodeoxyribonuclease III
PAKAOEHF_00549 1.5e-83
PAKAOEHF_00550 1e-187 lacR K Transcriptional regulator
PAKAOEHF_00551 0.0 lacS G Transporter
PAKAOEHF_00552 0.0 lacZ 3.2.1.23 G -beta-galactosidase
PAKAOEHF_00553 1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PAKAOEHF_00554 3.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PAKAOEHF_00555 3.9e-144 XK27_00940 1.2.1.70, 3.5.1.9 S Putative cyclase
PAKAOEHF_00556 5.5e-222 yxjG_1 E methionine synthase, vitamin-B12 independent
PAKAOEHF_00557 5.2e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PAKAOEHF_00558 8.2e-224 mdtG EGP Major facilitator Superfamily
PAKAOEHF_00559 6.4e-167 T Calcineurin-like phosphoesterase superfamily domain
PAKAOEHF_00560 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PAKAOEHF_00562 9.9e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PAKAOEHF_00563 2e-142 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PAKAOEHF_00564 1.6e-105 ahpC 1.11.1.15 O Peroxiredoxin
PAKAOEHF_00565 0.0 trxB2 1.8.1.9 C Thioredoxin domain
PAKAOEHF_00566 0.0 M LPXTG-motif cell wall anchor domain protein
PAKAOEHF_00569 4e-170 whiA K May be required for sporulation
PAKAOEHF_00570 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PAKAOEHF_00571 1.1e-161 rapZ S Displays ATPase and GTPase activities
PAKAOEHF_00572 7.1e-245 steT E amino acid
PAKAOEHF_00573 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PAKAOEHF_00574 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PAKAOEHF_00575 1.5e-13
PAKAOEHF_00576 6.6e-116 yfbR S HD containing hydrolase-like enzyme
PAKAOEHF_00577 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PAKAOEHF_00578 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
PAKAOEHF_00579 1.1e-161 aatB ET PFAM extracellular solute-binding protein, family 3
PAKAOEHF_00580 1e-215 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PAKAOEHF_00581 1e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PAKAOEHF_00582 4e-158 lutA C Cysteine-rich domain
PAKAOEHF_00583 5.8e-288 lutB C 4Fe-4S dicluster domain
PAKAOEHF_00584 3.9e-136 yrjD S LUD domain
PAKAOEHF_00585 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PAKAOEHF_00586 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PAKAOEHF_00587 1.1e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PAKAOEHF_00588 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PAKAOEHF_00589 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PAKAOEHF_00590 3.1e-32 KT PspC domain protein
PAKAOEHF_00591 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PAKAOEHF_00592 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PAKAOEHF_00593 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PAKAOEHF_00594 6.5e-114 comFC S Competence protein
PAKAOEHF_00595 1.3e-254 comFA L Helicase C-terminal domain protein
PAKAOEHF_00596 2.3e-108 yvyE 3.4.13.9 S YigZ family
PAKAOEHF_00597 3e-39 C nitroreductase
PAKAOEHF_00598 3.7e-236 EGP Major facilitator Superfamily
PAKAOEHF_00599 3.3e-68 rmaI K Transcriptional regulator
PAKAOEHF_00600 7.8e-39
PAKAOEHF_00601 0.0 ydaO E amino acid
PAKAOEHF_00602 1.3e-304 ybeC E amino acid
PAKAOEHF_00603 1.8e-84 S Aminoacyl-tRNA editing domain
PAKAOEHF_00604 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PAKAOEHF_00605 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PAKAOEHF_00607 8.2e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PAKAOEHF_00608 0.0 uup S ABC transporter, ATP-binding protein
PAKAOEHF_00609 3.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAKAOEHF_00610 8.5e-226 mtnE 2.6.1.83 E Aminotransferase
PAKAOEHF_00611 4.6e-143 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PAKAOEHF_00612 3.8e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PAKAOEHF_00613 2.1e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PAKAOEHF_00614 3.6e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PAKAOEHF_00615 4.2e-197 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PAKAOEHF_00616 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PAKAOEHF_00617 2.3e-125 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PAKAOEHF_00618 1.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PAKAOEHF_00619 3.3e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PAKAOEHF_00620 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PAKAOEHF_00621 6.3e-282 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PAKAOEHF_00622 4.8e-137 fat 3.1.2.21 I Acyl-ACP thioesterase
PAKAOEHF_00623 6.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PAKAOEHF_00624 5.9e-58 yabA L Involved in initiation control of chromosome replication
PAKAOEHF_00625 8.2e-185 holB 2.7.7.7 L DNA polymerase III
PAKAOEHF_00626 7.6e-52 yaaQ S Cyclic-di-AMP receptor
PAKAOEHF_00627 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PAKAOEHF_00628 9.7e-39 S Protein of unknown function (DUF2508)
PAKAOEHF_00629 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PAKAOEHF_00630 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PAKAOEHF_00631 8.6e-302 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAKAOEHF_00632 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PAKAOEHF_00633 3.4e-35 nrdH O Glutaredoxin
PAKAOEHF_00634 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAKAOEHF_00635 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PAKAOEHF_00636 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PAKAOEHF_00637 3.9e-131 S Putative adhesin
PAKAOEHF_00638 1.1e-70 XK27_06920 S Protein of unknown function (DUF1700)
PAKAOEHF_00639 1.2e-55 K transcriptional regulator PadR family
PAKAOEHF_00640 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PAKAOEHF_00642 7.7e-48
PAKAOEHF_00643 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PAKAOEHF_00644 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PAKAOEHF_00645 3.1e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PAKAOEHF_00646 4e-245 M Glycosyl transferase family group 2
PAKAOEHF_00648 1e-226 aadAT EK Aminotransferase, class I
PAKAOEHF_00649 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PAKAOEHF_00650 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PAKAOEHF_00651 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
PAKAOEHF_00652 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PAKAOEHF_00653 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PAKAOEHF_00654 4.7e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PAKAOEHF_00655 2.5e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PAKAOEHF_00656 3.8e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PAKAOEHF_00657 1.7e-207 yacL S domain protein
PAKAOEHF_00658 2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PAKAOEHF_00659 7.3e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
PAKAOEHF_00660 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
PAKAOEHF_00661 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PAKAOEHF_00662 6.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
PAKAOEHF_00663 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PAKAOEHF_00664 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKAOEHF_00665 1.1e-119 tcyB E ABC transporter
PAKAOEHF_00666 7.7e-216 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PAKAOEHF_00667 1.2e-168 I alpha/beta hydrolase fold
PAKAOEHF_00668 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PAKAOEHF_00669 0.0 S Bacterial membrane protein, YfhO
PAKAOEHF_00670 2.9e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
PAKAOEHF_00671 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PAKAOEHF_00673 7.3e-85 ydcK S Belongs to the SprT family
PAKAOEHF_00674 0.0 yhgF K Tex-like protein N-terminal domain protein
PAKAOEHF_00675 3.3e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PAKAOEHF_00676 1.2e-282 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PAKAOEHF_00677 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
PAKAOEHF_00678 6.9e-130 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PAKAOEHF_00679 1e-298 aspT P Predicted Permease Membrane Region
PAKAOEHF_00680 2.6e-250 EGP Major facilitator Superfamily
PAKAOEHF_00681 1.4e-110
PAKAOEHF_00684 9.1e-150 yjjH S Calcineurin-like phosphoesterase
PAKAOEHF_00685 1.3e-263 dtpT U amino acid peptide transporter
PAKAOEHF_00686 2.8e-19
PAKAOEHF_00690 2.2e-128 L Helix-turn-helix domain
PAKAOEHF_00691 2.2e-156 L hmm pf00665
PAKAOEHF_00692 8e-120 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
PAKAOEHF_00693 1.9e-159 mleP3 S Membrane transport protein
PAKAOEHF_00694 2.7e-224 4.4.1.8 E Aminotransferase, class I
PAKAOEHF_00695 4.4e-99 M Protein of unknown function (DUF3737)
PAKAOEHF_00696 8.6e-56 yphJ 4.1.1.44 S decarboxylase
PAKAOEHF_00697 2.3e-164 S Oxidoreductase, aldo keto reductase family protein
PAKAOEHF_00698 4.2e-86 C Flavodoxin
PAKAOEHF_00699 9.4e-17
PAKAOEHF_00700 4.8e-149 K Transcriptional regulator
PAKAOEHF_00701 7e-87 lacA S transferase hexapeptide repeat
PAKAOEHF_00702 3.3e-135 S Hydrolases of the alpha beta superfamily
PAKAOEHF_00703 1.5e-150 S Alpha beta hydrolase
PAKAOEHF_00704 7.7e-171 L transposase, IS605 OrfB family
PAKAOEHF_00705 2.7e-94 padC Q Phenolic acid decarboxylase
PAKAOEHF_00706 5.9e-94 padR K Virulence activator alpha C-term
PAKAOEHF_00707 1.1e-65 GM NAD(P)H-binding
PAKAOEHF_00708 4.3e-154 ypuA S Protein of unknown function (DUF1002)
PAKAOEHF_00709 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
PAKAOEHF_00710 9.3e-137 K Transcriptional regulator
PAKAOEHF_00711 2.9e-162 akr5f 1.1.1.346 S reductase
PAKAOEHF_00712 1.8e-104 K Transcriptional regulator C-terminal region
PAKAOEHF_00713 6.2e-189 S membrane
PAKAOEHF_00714 1.2e-112 GM NAD(P)H-binding
PAKAOEHF_00715 1.1e-64 yneR
PAKAOEHF_00716 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
PAKAOEHF_00717 2.4e-142 T EAL domain
PAKAOEHF_00718 3.4e-247 pgaC GT2 M Glycosyl transferase
PAKAOEHF_00719 8e-85
PAKAOEHF_00720 7.1e-201 2.7.7.65 T GGDEF domain
PAKAOEHF_00721 1.8e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
PAKAOEHF_00722 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PAKAOEHF_00723 1.4e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
PAKAOEHF_00724 1.5e-92 folT S ECF transporter, substrate-specific component
PAKAOEHF_00725 0.0 pepN 3.4.11.2 E aminopeptidase
PAKAOEHF_00726 1.5e-112 ylbE GM NAD dependent epimerase dehydratase family protein
PAKAOEHF_00727 1.5e-255 pepC 3.4.22.40 E aminopeptidase
PAKAOEHF_00728 1e-210 EGP Major facilitator Superfamily
PAKAOEHF_00729 6.5e-235
PAKAOEHF_00730 6.2e-84 K Transcriptional regulator, HxlR family
PAKAOEHF_00731 9.7e-109 XK27_02070 S Nitroreductase family
PAKAOEHF_00732 2.5e-52 hxlR K Transcriptional regulator, HxlR family
PAKAOEHF_00733 7.8e-120 GM NmrA-like family
PAKAOEHF_00734 1.6e-76 elaA S Gnat family
PAKAOEHF_00735 2.4e-39 S Cytochrome B5
PAKAOEHF_00736 5.4e-09 S Cytochrome B5
PAKAOEHF_00737 3.5e-41 S Cytochrome B5
PAKAOEHF_00738 2.3e-212 yxjG_1 E methionine synthase, vitamin-B12 independent
PAKAOEHF_00740 1.4e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PAKAOEHF_00741 2.4e-240 E amino acid
PAKAOEHF_00742 6.4e-262 npp S type I phosphodiesterase nucleotide pyrophosphatase
PAKAOEHF_00743 1.2e-227 yxiO S Vacuole effluxer Atg22 like
PAKAOEHF_00745 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PAKAOEHF_00746 5.2e-34
PAKAOEHF_00747 3.9e-290 mntH P H( )-stimulated, divalent metal cation uptake system
PAKAOEHF_00748 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
PAKAOEHF_00749 2.6e-86 ygfC K transcriptional regulator (TetR family)
PAKAOEHF_00750 6.8e-174 hrtB V ABC transporter permease
PAKAOEHF_00751 1.2e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PAKAOEHF_00752 5.6e-175 yhcA V ABC transporter, ATP-binding protein
PAKAOEHF_00753 3.4e-159 yhcA V ABC transporter, ATP-binding protein
PAKAOEHF_00754 1e-37
PAKAOEHF_00755 4.1e-50 czrA K Transcriptional regulator, ArsR family
PAKAOEHF_00756 3.3e-239 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PAKAOEHF_00757 2.5e-167 scrR K Transcriptional regulator, LacI family
PAKAOEHF_00758 1e-24
PAKAOEHF_00759 5.5e-107
PAKAOEHF_00760 9e-207 yttB EGP Major facilitator Superfamily
PAKAOEHF_00761 3.7e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
PAKAOEHF_00762 3.5e-88
PAKAOEHF_00763 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
PAKAOEHF_00764 1.2e-263 S Putative peptidoglycan binding domain
PAKAOEHF_00765 1.4e-124 yciB M ErfK YbiS YcfS YnhG
PAKAOEHF_00767 4.6e-100
PAKAOEHF_00768 3.5e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PAKAOEHF_00769 7e-126 S Alpha beta hydrolase
PAKAOEHF_00770 7.6e-208 gldA 1.1.1.6 C dehydrogenase
PAKAOEHF_00771 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PAKAOEHF_00772 1.3e-41
PAKAOEHF_00773 5.5e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
PAKAOEHF_00774 5.3e-284 S C4-dicarboxylate anaerobic carrier
PAKAOEHF_00775 2.7e-250 nhaC C Na H antiporter NhaC
PAKAOEHF_00776 3.6e-241 pbuX F xanthine permease
PAKAOEHF_00777 7e-283 pipD E Dipeptidase
PAKAOEHF_00778 9.7e-169 corA P CorA-like Mg2+ transporter protein
PAKAOEHF_00779 2e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PAKAOEHF_00780 2.3e-131 terC P membrane
PAKAOEHF_00781 2.1e-54 trxA O Belongs to the thioredoxin family
PAKAOEHF_00782 2.7e-236 mepA V MATE efflux family protein
PAKAOEHF_00783 1.1e-92 M domain protein
PAKAOEHF_00784 3.4e-178 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PAKAOEHF_00785 2.2e-159 rrmA 2.1.1.187 H Methyltransferase
PAKAOEHF_00786 3e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PAKAOEHF_00787 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PAKAOEHF_00788 1.2e-10 S Protein of unknown function (DUF4044)
PAKAOEHF_00789 1.7e-57
PAKAOEHF_00790 3.1e-77 mraZ K Belongs to the MraZ family
PAKAOEHF_00791 6.8e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PAKAOEHF_00792 1.5e-56 ftsL D Cell division protein FtsL
PAKAOEHF_00793 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PAKAOEHF_00794 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PAKAOEHF_00795 2.7e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PAKAOEHF_00796 4.3e-203 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PAKAOEHF_00797 1.6e-149 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PAKAOEHF_00798 9.5e-253 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PAKAOEHF_00799 1.5e-225 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PAKAOEHF_00800 1.2e-70 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PAKAOEHF_00801 8.3e-41 yggT S YGGT family
PAKAOEHF_00802 1.9e-144 ylmH S S4 domain protein
PAKAOEHF_00803 1.9e-42 divIVA D DivIVA domain protein
PAKAOEHF_00804 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PAKAOEHF_00805 4.2e-32 cspA K Cold shock protein
PAKAOEHF_00806 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PAKAOEHF_00808 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PAKAOEHF_00809 3.5e-216 iscS 2.8.1.7 E Aminotransferase class V
PAKAOEHF_00810 7.5e-58 XK27_04120 S Putative amino acid metabolism
PAKAOEHF_00811 1.6e-218 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PAKAOEHF_00812 3.7e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PAKAOEHF_00813 9e-119 S Repeat protein
PAKAOEHF_00814 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PAKAOEHF_00815 8.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PAKAOEHF_00816 3.8e-280 UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_00817 1.3e-156 UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_00818 5.2e-168 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PAKAOEHF_00819 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
PAKAOEHF_00820 1.4e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PAKAOEHF_00821 6.7e-77 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PAKAOEHF_00822 4.2e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PAKAOEHF_00823 2.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PAKAOEHF_00824 7.3e-141 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PAKAOEHF_00825 1.6e-219 patA 2.6.1.1 E Aminotransferase
PAKAOEHF_00826 3e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PAKAOEHF_00827 1.4e-83 KT Putative sugar diacid recognition
PAKAOEHF_00828 7.6e-220 EG GntP family permease
PAKAOEHF_00829 1.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PAKAOEHF_00830 2.2e-57
PAKAOEHF_00832 9.1e-137 mltD CBM50 M NlpC P60 family protein
PAKAOEHF_00833 5.7e-29
PAKAOEHF_00834 3.8e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
PAKAOEHF_00835 9.8e-32 ykzG S Belongs to the UPF0356 family
PAKAOEHF_00836 4.7e-82
PAKAOEHF_00837 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PAKAOEHF_00838 2e-208 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PAKAOEHF_00839 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PAKAOEHF_00840 8.7e-227 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PAKAOEHF_00841 1.4e-275 lpdA 1.8.1.4 C Dehydrogenase
PAKAOEHF_00842 1.4e-47 yktA S Belongs to the UPF0223 family
PAKAOEHF_00843 4.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PAKAOEHF_00844 0.0 typA T GTP-binding protein TypA
PAKAOEHF_00845 1.2e-222 ftsW D Belongs to the SEDS family
PAKAOEHF_00846 6.7e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PAKAOEHF_00847 1.4e-98 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PAKAOEHF_00848 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PAKAOEHF_00849 2.3e-198 ylbL T Belongs to the peptidase S16 family
PAKAOEHF_00850 6.9e-81 comEA L Competence protein ComEA
PAKAOEHF_00851 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
PAKAOEHF_00852 0.0 comEC S Competence protein ComEC
PAKAOEHF_00853 7.6e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
PAKAOEHF_00854 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
PAKAOEHF_00855 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PAKAOEHF_00856 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAKAOEHF_00857 1.3e-162 S Tetratricopeptide repeat
PAKAOEHF_00858 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PAKAOEHF_00859 1.1e-237 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PAKAOEHF_00860 6.2e-235 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PAKAOEHF_00861 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
PAKAOEHF_00862 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PAKAOEHF_00863 4.9e-08
PAKAOEHF_00864 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PAKAOEHF_00865 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PAKAOEHF_00866 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PAKAOEHF_00867 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKAOEHF_00868 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PAKAOEHF_00869 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PAKAOEHF_00870 2.5e-88
PAKAOEHF_00871 3.5e-133 L Belongs to the 'phage' integrase family
PAKAOEHF_00872 3.2e-12 xre K sequence-specific DNA binding
PAKAOEHF_00873 2.2e-14
PAKAOEHF_00874 1.5e-43 S Phage regulatory protein Rha (Phage_pRha)
PAKAOEHF_00877 6.6e-08
PAKAOEHF_00881 3.3e-13 L DnaD domain protein
PAKAOEHF_00883 3.8e-69
PAKAOEHF_00884 3e-07
PAKAOEHF_00885 1.4e-164 D NLP P60 protein
PAKAOEHF_00886 2.1e-191 D NLP P60 protein
PAKAOEHF_00888 3.1e-57
PAKAOEHF_00890 1.1e-126 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PAKAOEHF_00891 1.2e-211 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PAKAOEHF_00892 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PAKAOEHF_00893 1.3e-35 ynzC S UPF0291 protein
PAKAOEHF_00894 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
PAKAOEHF_00895 1.6e-117 plsC 2.3.1.51 I Acyltransferase
PAKAOEHF_00896 3e-139 yabB 2.1.1.223 L Methyltransferase small domain
PAKAOEHF_00897 2.1e-48 yazA L GIY-YIG catalytic domain protein
PAKAOEHF_00898 2e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAKAOEHF_00899 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
PAKAOEHF_00900 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PAKAOEHF_00901 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PAKAOEHF_00902 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PAKAOEHF_00903 8.4e-142 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PAKAOEHF_00904 5.8e-138 cdsA 2.7.7.41 I Belongs to the CDS family
PAKAOEHF_00905 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PAKAOEHF_00906 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PAKAOEHF_00907 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PAKAOEHF_00908 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
PAKAOEHF_00909 4.6e-211 nusA K Participates in both transcription termination and antitermination
PAKAOEHF_00910 1e-44 ylxR K Protein of unknown function (DUF448)
PAKAOEHF_00911 3.8e-48 ylxQ J ribosomal protein
PAKAOEHF_00912 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PAKAOEHF_00913 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PAKAOEHF_00914 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PAKAOEHF_00915 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PAKAOEHF_00916 7.6e-64
PAKAOEHF_00917 1.8e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PAKAOEHF_00918 1.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PAKAOEHF_00919 0.0 dnaK O Heat shock 70 kDa protein
PAKAOEHF_00920 7.3e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PAKAOEHF_00921 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PAKAOEHF_00922 1.1e-69 3.6.4.12 L Belongs to the 'phage' integrase family
PAKAOEHF_00923 1.7e-27 3.6.4.12 L Belongs to the 'phage' integrase family
PAKAOEHF_00924 2.6e-217 L Integrase core domain
PAKAOEHF_00925 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_00926 1.2e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PAKAOEHF_00927 1.9e-199 XK27_09615 S reductase
PAKAOEHF_00928 4.9e-102 nqr 1.5.1.36 S reductase
PAKAOEHF_00930 4.8e-268 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAKAOEHF_00931 7.1e-181 K Transcriptional regulator, LacI family
PAKAOEHF_00932 3.6e-260 G Major Facilitator
PAKAOEHF_00933 4.8e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PAKAOEHF_00934 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PAKAOEHF_00935 1.5e-266 G Major Facilitator
PAKAOEHF_00936 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
PAKAOEHF_00937 3.3e-288 M domain protein
PAKAOEHF_00938 3.9e-268 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
PAKAOEHF_00939 4.8e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
PAKAOEHF_00940 1e-69
PAKAOEHF_00941 9e-113 K Transcriptional regulator, TetR family
PAKAOEHF_00943 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PAKAOEHF_00944 1.4e-86
PAKAOEHF_00945 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PAKAOEHF_00946 8.4e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PAKAOEHF_00947 3.5e-260 nox C NADH oxidase
PAKAOEHF_00948 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
PAKAOEHF_00949 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
PAKAOEHF_00950 2.3e-167 yvgN C Aldo keto reductase
PAKAOEHF_00951 5e-136 puuD S peptidase C26
PAKAOEHF_00952 1.1e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PAKAOEHF_00953 4.4e-206 yfeO P Voltage gated chloride channel
PAKAOEHF_00954 1e-221 sptS 2.7.13.3 T Histidine kinase
PAKAOEHF_00955 7.6e-115 K response regulator
PAKAOEHF_00956 1.3e-87 2.7.6.5 T Region found in RelA / SpoT proteins
PAKAOEHF_00957 4.2e-70
PAKAOEHF_00958 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
PAKAOEHF_00959 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PAKAOEHF_00960 6.9e-256 malT G Major Facilitator
PAKAOEHF_00961 3.2e-209 phbA 2.3.1.9 I Belongs to the thiolase family
PAKAOEHF_00962 3.5e-174 malR K Transcriptional regulator, LacI family
PAKAOEHF_00963 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PAKAOEHF_00964 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PAKAOEHF_00965 2.6e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAKAOEHF_00966 3.7e-105 wecD3 K PFAM GCN5-related N-acetyltransferase
PAKAOEHF_00968 2.2e-128 L Helix-turn-helix domain
PAKAOEHF_00969 2.2e-156 L hmm pf00665
PAKAOEHF_00970 0.0 fhaB M Rib/alpha-like repeat
PAKAOEHF_00971 3.8e-64 infB UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_00972 1.5e-57 infB UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_00993 9.5e-155 KT YcbB domain
PAKAOEHF_00994 5.8e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PAKAOEHF_00995 5.6e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
PAKAOEHF_00996 4.3e-161 EG EamA-like transporter family
PAKAOEHF_00997 8.5e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PAKAOEHF_00998 3.3e-51 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PAKAOEHF_00999 2.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
PAKAOEHF_01000 0.0 copA 3.6.3.54 P P-type ATPase
PAKAOEHF_01001 3e-89
PAKAOEHF_01003 3.6e-57
PAKAOEHF_01004 2.6e-254 yjcE P Sodium proton antiporter
PAKAOEHF_01006 7.6e-91
PAKAOEHF_01007 0.0 M domain protein
PAKAOEHF_01008 7.7e-34
PAKAOEHF_01009 3.9e-195 ampC V Beta-lactamase
PAKAOEHF_01010 5.9e-238 arcA 3.5.3.6 E Arginine
PAKAOEHF_01011 2.7e-79 argR K Regulates arginine biosynthesis genes
PAKAOEHF_01012 9.8e-261 E Arginine ornithine antiporter
PAKAOEHF_01013 1.2e-221 arcD U Amino acid permease
PAKAOEHF_01014 4.1e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
PAKAOEHF_01015 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
PAKAOEHF_01016 6e-108 tdk 2.7.1.21 F thymidine kinase
PAKAOEHF_01017 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PAKAOEHF_01018 1e-167 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PAKAOEHF_01019 1.6e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PAKAOEHF_01020 2.5e-228 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PAKAOEHF_01021 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PAKAOEHF_01022 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PAKAOEHF_01023 4.4e-192 yibE S overlaps another CDS with the same product name
PAKAOEHF_01024 2.2e-129 yibF S overlaps another CDS with the same product name
PAKAOEHF_01025 5.9e-233 pyrP F Permease
PAKAOEHF_01026 7.6e-121 atpB C it plays a direct role in the translocation of protons across the membrane
PAKAOEHF_01027 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PAKAOEHF_01028 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PAKAOEHF_01029 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PAKAOEHF_01030 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PAKAOEHF_01031 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PAKAOEHF_01032 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PAKAOEHF_01033 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PAKAOEHF_01034 1.3e-33 ywzB S Protein of unknown function (DUF1146)
PAKAOEHF_01035 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAKAOEHF_01036 1.9e-178 mbl D Cell shape determining protein MreB Mrl
PAKAOEHF_01037 1e-31 S Protein of unknown function (DUF2969)
PAKAOEHF_01038 1.1e-220 rodA D Belongs to the SEDS family
PAKAOEHF_01039 3e-47 gcvH E glycine cleavage
PAKAOEHF_01040 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PAKAOEHF_01041 7.9e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PAKAOEHF_01042 3.5e-217 lacY G Oligosaccharide H symporter
PAKAOEHF_01043 1.3e-168 abf G Belongs to the glycosyl hydrolase 43 family
PAKAOEHF_01044 2.5e-145 K transcriptional regulator, ArsR family
PAKAOEHF_01045 3.4e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
PAKAOEHF_01046 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
PAKAOEHF_01047 4.9e-139 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PAKAOEHF_01048 6.3e-284 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PAKAOEHF_01049 1.3e-99 maa 2.3.1.79 S Maltose O-acetyltransferase
PAKAOEHF_01050 6e-157 ytbE 1.1.1.346 S Aldo keto reductase
PAKAOEHF_01051 2.2e-207 araR K Transcriptional regulator
PAKAOEHF_01052 4.3e-83 usp6 T universal stress protein
PAKAOEHF_01053 4.4e-46
PAKAOEHF_01054 3.4e-244 rarA L recombination factor protein RarA
PAKAOEHF_01055 6e-85 yueI S Protein of unknown function (DUF1694)
PAKAOEHF_01056 1.5e-21
PAKAOEHF_01057 8.1e-75 4.4.1.5 E Glyoxalase
PAKAOEHF_01058 2.5e-138 S Membrane
PAKAOEHF_01059 2.7e-140 S Belongs to the UPF0246 family
PAKAOEHF_01060 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
PAKAOEHF_01061 4.4e-263 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PAKAOEHF_01062 1.3e-235 pbuG S permease
PAKAOEHF_01065 5.4e-67 XK27_01125 L PFAM IS66 Orf2 family protein
PAKAOEHF_01066 1e-125 L Transposase IS66 family
PAKAOEHF_01067 2.6e-217 L Integrase core domain
PAKAOEHF_01068 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_01070 1.4e-284 GT2,GT4 M family 8
PAKAOEHF_01071 5e-202 M family 8
PAKAOEHF_01072 6.7e-70 M family 8
PAKAOEHF_01074 3.9e-259 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PAKAOEHF_01075 6.8e-292 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PAKAOEHF_01076 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PAKAOEHF_01077 7e-164 asp3 S Accessory Sec secretory system ASP3
PAKAOEHF_01078 1.5e-288 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
PAKAOEHF_01079 3.1e-289 M transferase activity, transferring glycosyl groups
PAKAOEHF_01080 1.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
PAKAOEHF_01081 4e-103 cpsJ S glycosyl transferase family 2
PAKAOEHF_01082 9.5e-194 nss M transferase activity, transferring glycosyl groups
PAKAOEHF_01084 2.1e-109 dedA S SNARE-like domain protein
PAKAOEHF_01085 1.8e-105 S Protein of unknown function (DUF1461)
PAKAOEHF_01086 2.5e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PAKAOEHF_01087 6e-94 yutD S Protein of unknown function (DUF1027)
PAKAOEHF_01088 3.8e-113 S Calcineurin-like phosphoesterase
PAKAOEHF_01089 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PAKAOEHF_01090 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
PAKAOEHF_01092 4.9e-70
PAKAOEHF_01093 2.4e-41
PAKAOEHF_01094 3.7e-78 NU general secretion pathway protein
PAKAOEHF_01095 7.1e-47 comGC U competence protein ComGC
PAKAOEHF_01096 5.4e-184 comGB NU type II secretion system
PAKAOEHF_01097 1.2e-180 comGA NU Type II IV secretion system protein
PAKAOEHF_01098 3.5e-132 yebC K Transcriptional regulatory protein
PAKAOEHF_01099 4.2e-134
PAKAOEHF_01100 2.2e-182 ccpA K catabolite control protein A
PAKAOEHF_01101 3.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PAKAOEHF_01102 1.5e-29
PAKAOEHF_01103 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PAKAOEHF_01104 1.7e-146 ykuT M mechanosensitive ion channel
PAKAOEHF_01105 1.2e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
PAKAOEHF_01106 1.8e-75 ykuL S (CBS) domain
PAKAOEHF_01107 5.9e-94 S Phosphoesterase
PAKAOEHF_01108 3.3e-101 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PAKAOEHF_01109 1.2e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PAKAOEHF_01110 4.6e-97 yslB S Protein of unknown function (DUF2507)
PAKAOEHF_01111 6.1e-54 trxA O Belongs to the thioredoxin family
PAKAOEHF_01112 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PAKAOEHF_01113 1.6e-86 cvpA S Colicin V production protein
PAKAOEHF_01114 6.1e-48 yrzB S Belongs to the UPF0473 family
PAKAOEHF_01115 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PAKAOEHF_01116 4.1e-43 yrzL S Belongs to the UPF0297 family
PAKAOEHF_01117 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PAKAOEHF_01118 8.3e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PAKAOEHF_01119 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PAKAOEHF_01120 2.8e-31 yajC U Preprotein translocase
PAKAOEHF_01121 9e-190 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PAKAOEHF_01122 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PAKAOEHF_01123 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PAKAOEHF_01124 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PAKAOEHF_01125 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PAKAOEHF_01126 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
PAKAOEHF_01127 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PAKAOEHF_01128 2.3e-229 cinA 3.5.1.42 S Belongs to the CinA family
PAKAOEHF_01129 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PAKAOEHF_01130 1.1e-139 ymfM S Helix-turn-helix domain
PAKAOEHF_01131 3.5e-249 ymfH S Peptidase M16
PAKAOEHF_01132 7.8e-230 ymfF S Peptidase M16 inactive domain protein
PAKAOEHF_01133 2.6e-160 aatB ET ABC transporter substrate-binding protein
PAKAOEHF_01134 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKAOEHF_01135 3.2e-102 glnP P ABC transporter permease
PAKAOEHF_01136 8.7e-93 mreD M rod shape-determining protein MreD
PAKAOEHF_01137 5.9e-152 mreC M Involved in formation and maintenance of cell shape
PAKAOEHF_01138 1.7e-179 mreB D cell shape determining protein MreB
PAKAOEHF_01139 6.8e-121 radC L DNA repair protein
PAKAOEHF_01140 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PAKAOEHF_01141 9e-231 ndh 1.6.99.3 C NADH dehydrogenase
PAKAOEHF_01142 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PAKAOEHF_01143 2e-308 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PAKAOEHF_01144 4.1e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PAKAOEHF_01145 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
PAKAOEHF_01146 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PAKAOEHF_01147 2.5e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PAKAOEHF_01148 3.5e-216 iscS2 2.8.1.7 E Aminotransferase class V
PAKAOEHF_01149 1.7e-251 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PAKAOEHF_01150 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PAKAOEHF_01151 1.7e-290 gadC E amino acid
PAKAOEHF_01152 3e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
PAKAOEHF_01153 4.3e-286 gadC E amino acid
PAKAOEHF_01154 1e-281 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
PAKAOEHF_01155 2.7e-119 L Transposase
PAKAOEHF_01156 2.7e-119 L Transposase
PAKAOEHF_01157 2.7e-26
PAKAOEHF_01158 1.3e-262 pgi 5.3.1.9 G Belongs to the GPI family
PAKAOEHF_01159 4e-102 lacA 2.3.1.79 S Transferase hexapeptide repeat
PAKAOEHF_01160 3.4e-155 glcU U sugar transport
PAKAOEHF_01161 2.4e-273 yclK 2.7.13.3 T Histidine kinase
PAKAOEHF_01162 3e-133 K response regulator
PAKAOEHF_01164 1.8e-78 lytE M Lysin motif
PAKAOEHF_01165 7e-147 XK27_02985 S Cof-like hydrolase
PAKAOEHF_01166 2.3e-81 K Transcriptional regulator
PAKAOEHF_01167 0.0 oatA I Acyltransferase
PAKAOEHF_01168 8.7e-53
PAKAOEHF_01169 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PAKAOEHF_01170 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PAKAOEHF_01171 2e-126 ybbR S YbbR-like protein
PAKAOEHF_01172 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PAKAOEHF_01173 3.7e-249 fucP G Major Facilitator Superfamily
PAKAOEHF_01174 5.1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PAKAOEHF_01175 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PAKAOEHF_01176 1.6e-168 murB 1.3.1.98 M Cell wall formation
PAKAOEHF_01177 1.7e-101 dnaQ 2.7.7.7 L DNA polymerase III
PAKAOEHF_01178 4.4e-76 S PAS domain
PAKAOEHF_01179 3.9e-87 K Acetyltransferase (GNAT) domain
PAKAOEHF_01180 2.2e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PAKAOEHF_01181 8.4e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PAKAOEHF_01182 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PAKAOEHF_01183 3.7e-105 yxjI
PAKAOEHF_01184 4.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PAKAOEHF_01185 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PAKAOEHF_01186 8.8e-147 est 3.1.1.1 S Serine aminopeptidase, S33
PAKAOEHF_01187 1.8e-34 secG U Preprotein translocase
PAKAOEHF_01188 5.6e-294 clcA P chloride
PAKAOEHF_01189 7.1e-248 yifK E Amino acid permease
PAKAOEHF_01190 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PAKAOEHF_01191 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PAKAOEHF_01192 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PAKAOEHF_01193 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PAKAOEHF_01195 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PAKAOEHF_01196 5.7e-242 glpT G Major Facilitator Superfamily
PAKAOEHF_01197 8.8e-15
PAKAOEHF_01199 4.5e-165 L Transposase
PAKAOEHF_01200 1.2e-55 K Transcriptional regulator, ArsR family
PAKAOEHF_01201 1e-91 P Cadmium resistance transporter
PAKAOEHF_01202 3.7e-137 XK27_08845 S ABC transporter, ATP-binding protein
PAKAOEHF_01203 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PAKAOEHF_01204 9.8e-183 ABC-SBP S ABC transporter
PAKAOEHF_01205 2.7e-71 M PFAM NLP P60 protein
PAKAOEHF_01206 8.1e-08 S Domain of unknown function (DUF296)
PAKAOEHF_01208 2.9e-11
PAKAOEHF_01209 4.2e-273 S ABC transporter, ATP-binding protein
PAKAOEHF_01210 2e-143 S Putative ABC-transporter type IV
PAKAOEHF_01211 1.3e-105 NU mannosyl-glycoprotein
PAKAOEHF_01212 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
PAKAOEHF_01213 1.9e-214 S Uncharacterized protein conserved in bacteria (DUF2325)
PAKAOEHF_01214 1.7e-204 nrnB S DHHA1 domain
PAKAOEHF_01216 1.7e-12 K Helix-turn-helix domain
PAKAOEHF_01220 6.3e-50
PAKAOEHF_01221 2.5e-136 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PAKAOEHF_01222 1e-19 S Domain of unknown function (DUF4767)
PAKAOEHF_01223 3.6e-54
PAKAOEHF_01224 2.4e-116 yrkL S Flavodoxin-like fold
PAKAOEHF_01226 1.4e-65 yeaO S Protein of unknown function, DUF488
PAKAOEHF_01227 1.2e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PAKAOEHF_01228 1.2e-203 3.1.3.1 S associated with various cellular activities
PAKAOEHF_01229 2.6e-236 S Putative metallopeptidase domain
PAKAOEHF_01230 4.6e-48
PAKAOEHF_01231 0.0 pepO 3.4.24.71 O Peptidase family M13
PAKAOEHF_01232 3.3e-104 K Helix-turn-helix XRE-family like proteins
PAKAOEHF_01233 8.4e-90 ymdB S Macro domain protein
PAKAOEHF_01234 2.4e-196 EGP Major facilitator Superfamily
PAKAOEHF_01235 3.2e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PAKAOEHF_01236 3.6e-54 K helix_turn_helix, mercury resistance
PAKAOEHF_01237 9.1e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PAKAOEHF_01238 1.1e-158 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PAKAOEHF_01239 0.0 ysaB V FtsX-like permease family
PAKAOEHF_01240 7.5e-135 macB2 V ABC transporter, ATP-binding protein
PAKAOEHF_01241 2.5e-183 T PhoQ Sensor
PAKAOEHF_01242 1.4e-124 K response regulator
PAKAOEHF_01243 8.6e-156 ytbE 1.1.1.346 S Aldo keto reductase
PAKAOEHF_01244 1.8e-136 pnuC H nicotinamide mononucleotide transporter
PAKAOEHF_01245 3.7e-82 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PAKAOEHF_01246 1.5e-203
PAKAOEHF_01247 2.6e-52
PAKAOEHF_01248 9.1e-36
PAKAOEHF_01249 6.3e-93 yxkA S Phosphatidylethanolamine-binding protein
PAKAOEHF_01250 1.5e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
PAKAOEHF_01251 2.8e-182 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
PAKAOEHF_01252 3.2e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PAKAOEHF_01253 1.5e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PAKAOEHF_01254 1.2e-180 galR K Transcriptional regulator
PAKAOEHF_01255 1.6e-98 dedA 3.1.3.1 S SNARE associated Golgi protein
PAKAOEHF_01256 3e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PAKAOEHF_01257 1.5e-80 K AsnC family
PAKAOEHF_01258 3.3e-80 uspA T universal stress protein
PAKAOEHF_01259 4e-09 ltrA S Bacterial low temperature requirement A protein (LtrA)
PAKAOEHF_01260 4.9e-287 lacS G Transporter
PAKAOEHF_01261 4.2e-40
PAKAOEHF_01262 1.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PAKAOEHF_01263 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PAKAOEHF_01264 2.6e-192 yeaN P Transporter, major facilitator family protein
PAKAOEHF_01265 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
PAKAOEHF_01266 9.9e-85 nrdI F Belongs to the NrdI family
PAKAOEHF_01267 1.9e-242 yhdP S Transporter associated domain
PAKAOEHF_01268 9.8e-155 ypdB V (ABC) transporter
PAKAOEHF_01269 6.7e-90 GM epimerase
PAKAOEHF_01270 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
PAKAOEHF_01271 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
PAKAOEHF_01272 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
PAKAOEHF_01273 1e-172 S AI-2E family transporter
PAKAOEHF_01274 1.1e-158 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PAKAOEHF_01275 2.1e-163
PAKAOEHF_01276 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PAKAOEHF_01277 2.3e-148 eutJ E Hsp70 protein
PAKAOEHF_01278 4.7e-199 K helix_turn_helix, arabinose operon control protein
PAKAOEHF_01279 6.2e-42 pduA_4 CQ BMC
PAKAOEHF_01280 4.6e-134 pduB E BMC
PAKAOEHF_01281 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
PAKAOEHF_01282 1.1e-127 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
PAKAOEHF_01283 3.7e-77 pduE 4.2.1.28 Q Dehydratase small subunit
PAKAOEHF_01284 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
PAKAOEHF_01285 6.5e-60 pduH S Dehydratase medium subunit
PAKAOEHF_01286 1.4e-72 pduK CQ BMC
PAKAOEHF_01287 2.2e-42 pduA_4 CQ BMC
PAKAOEHF_01288 4.2e-118 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
PAKAOEHF_01289 6.4e-90 S Putative propanediol utilisation
PAKAOEHF_01290 1.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
PAKAOEHF_01291 3.7e-105 pduO 2.5.1.17 S Cobalamin adenosyltransferase
PAKAOEHF_01292 7.4e-80 pduO S Haem-degrading
PAKAOEHF_01293 6.8e-270 pduP 1.2.1.87 C Aldehyde dehydrogenase family
PAKAOEHF_01294 1.3e-210 pduQ C Iron-containing alcohol dehydrogenase
PAKAOEHF_01295 2.2e-221 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PAKAOEHF_01296 5.5e-56 pduU E BMC
PAKAOEHF_01297 4.1e-147 3.1.3.48 T Pfam:Y_phosphatase3C
PAKAOEHF_01298 6.5e-119 pgm1 3.1.3.73 G phosphoglycerate mutase
PAKAOEHF_01299 6.7e-80 P Cadmium resistance transporter
PAKAOEHF_01300 3e-72 eutP E Ethanolamine utilisation - propanediol utilisation
PAKAOEHF_01301 1.5e-77 fld C Flavodoxin
PAKAOEHF_01302 6.6e-156 XK27_04590 S NADPH-dependent FMN reductase
PAKAOEHF_01303 1.8e-101 cobO 2.5.1.17 S Cobalamin adenosyltransferase
PAKAOEHF_01304 1.5e-205 cobD 4.1.1.81 E Aminotransferase class I and II
PAKAOEHF_01305 8e-260 cbiA 6.3.5.11, 6.3.5.9 F Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source
PAKAOEHF_01306 1.7e-179 cobD 6.3.1.10 H Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
PAKAOEHF_01307 2.1e-123 cbiC 5.4.99.60, 5.4.99.61 H Precorrin-8X methylmutase
PAKAOEHF_01308 4.3e-206 cbiD 2.1.1.195 H Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
PAKAOEHF_01309 1e-110 cbiE 2.1.1.132, 2.1.1.289 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PAKAOEHF_01310 2.1e-94 cbiT 2.1.1.132, 2.1.1.196 H Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
PAKAOEHF_01311 2e-135 cobM 1.3.1.76, 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 4.99.1.4 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PAKAOEHF_01312 3e-190 cbiG 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12 H Cobalamin synthesis G C-terminus
PAKAOEHF_01313 2.2e-131 cobJ 2.1.1.131, 2.1.1.133, 2.1.1.271, 3.7.1.12, 6.3.5.10 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PAKAOEHF_01314 2.9e-134 cobK 1.3.1.106, 1.3.1.54, 2.1.1.195 H Precorrin-6x reductase CbiJ/CobK
PAKAOEHF_01315 5.3e-259 cobA 2.1.1.107, 4.2.1.75 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PAKAOEHF_01316 2e-146 cbiK 4.99.1.3 H Cobalt chelatase (CbiK)
PAKAOEHF_01317 5.7e-124 cobI 2.1.1.130, 2.1.1.151, 4.99.1.3 H Tetrapyrrole (Corrin/Porphyrin) Methylases
PAKAOEHF_01318 7e-133 cbiM P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
PAKAOEHF_01319 1.9e-52 cbiN P Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
PAKAOEHF_01320 5.8e-118 cbiQ P Cobalt transport protein
PAKAOEHF_01321 1.7e-148 cbiO 2.1.1.195 P part of an ABC transporter complex. Responsible for energy coupling to the transport system
PAKAOEHF_01322 3.3e-275 cobQ 6.3.5.10 H Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation
PAKAOEHF_01323 3e-78 cysG 1.3.1.76, 4.99.1.4 H Putative NAD(P)-binding
PAKAOEHF_01324 2.3e-229 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PAKAOEHF_01325 5.5e-164 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PAKAOEHF_01326 3.8e-179 hemB 4.2.1.24 H Delta-aminolevulinic acid dehydratase
PAKAOEHF_01327 1.4e-250 hemL 5.4.3.8 H Aminotransferase class-III
PAKAOEHF_01328 4.6e-103 cobU 2.7.1.156, 2.7.7.62, 6.3.5.10 H Cobinamide kinase / cobinamide phosphate guanyltransferase
PAKAOEHF_01329 7.1e-133 cobS 2.7.8.26 H Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
PAKAOEHF_01330 7e-112 gpm 3.1.3.73, 5.4.2.12 G Belongs to the phosphoglycerate mutase family
PAKAOEHF_01331 5.8e-129 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PAKAOEHF_01332 6.5e-193 cobT 2.4.2.21, 6.3.5.11, 6.3.5.9 F Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)
PAKAOEHF_01333 8.1e-61 S Domain of unknown function (DUF4430)
PAKAOEHF_01334 1.2e-81 S ECF transporter, substrate-specific component
PAKAOEHF_01335 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_01336 2.6e-217 L Integrase core domain
PAKAOEHF_01338 5.4e-138 G Peptidase family M23
PAKAOEHF_01339 3.2e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PAKAOEHF_01340 4.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PAKAOEHF_01341 2.1e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PAKAOEHF_01342 2.7e-149 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PAKAOEHF_01343 6.4e-254 G Peptidase_C39 like family
PAKAOEHF_01344 4.3e-163 yueF S AI-2E family transporter
PAKAOEHF_01345 3.6e-226 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PAKAOEHF_01346 7.4e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PAKAOEHF_01347 0.0 M NlpC/P60 family
PAKAOEHF_01348 0.0 S Peptidase, M23
PAKAOEHF_01349 9.3e-65 gntR1 K Transcriptional regulator, GntR family
PAKAOEHF_01350 4.7e-157 V ABC transporter, ATP-binding protein
PAKAOEHF_01351 5.6e-113
PAKAOEHF_01352 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
PAKAOEHF_01353 2.2e-100 S Pfam:DUF3816
PAKAOEHF_01354 0.0 clpE O Belongs to the ClpA ClpB family
PAKAOEHF_01355 2.9e-27
PAKAOEHF_01356 2.7e-39 ptsH G phosphocarrier protein HPR
PAKAOEHF_01357 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PAKAOEHF_01358 1.9e-228 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PAKAOEHF_01359 1.6e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
PAKAOEHF_01360 3.9e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PAKAOEHF_01361 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
PAKAOEHF_01362 1.5e-236 S Tetratricopeptide repeat protein
PAKAOEHF_01363 6.9e-223 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PAKAOEHF_01364 0.0 yfmR S ABC transporter, ATP-binding protein
PAKAOEHF_01365 4.2e-191 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PAKAOEHF_01366 2.2e-72 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PAKAOEHF_01367 5.3e-113 hlyIII S protein, hemolysin III
PAKAOEHF_01368 1.4e-150 DegV S EDD domain protein, DegV family
PAKAOEHF_01369 5.2e-170 ypmR E lipolytic protein G-D-S-L family
PAKAOEHF_01370 7.4e-109 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PAKAOEHF_01371 4.4e-35 yozE S Belongs to the UPF0346 family
PAKAOEHF_01372 1.2e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PAKAOEHF_01373 1.7e-142 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PAKAOEHF_01374 9.9e-163 dprA LU DNA protecting protein DprA
PAKAOEHF_01375 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PAKAOEHF_01376 6.4e-170 lacX 5.1.3.3 G Aldose 1-epimerase
PAKAOEHF_01377 3.2e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PAKAOEHF_01378 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PAKAOEHF_01379 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PAKAOEHF_01380 2.2e-84 F NUDIX domain
PAKAOEHF_01381 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
PAKAOEHF_01382 4.1e-68 yqkB S Belongs to the HesB IscA family
PAKAOEHF_01383 1.6e-49
PAKAOEHF_01385 1.4e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PAKAOEHF_01386 1.3e-61 asp S Asp23 family, cell envelope-related function
PAKAOEHF_01387 2.3e-24
PAKAOEHF_01388 5.2e-93
PAKAOEHF_01389 1.4e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PAKAOEHF_01390 4.4e-183 K Transcriptional regulator, LacI family
PAKAOEHF_01391 6.3e-233 gntT EG Gluconate
PAKAOEHF_01392 3.8e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
PAKAOEHF_01393 2.2e-96 K Acetyltransferase (GNAT) domain
PAKAOEHF_01394 4.2e-47
PAKAOEHF_01395 0.0 nylA 3.5.1.4 J Belongs to the amidase family
PAKAOEHF_01396 2.2e-44
PAKAOEHF_01397 2.8e-58 yhaI S Protein of unknown function (DUF805)
PAKAOEHF_01398 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
PAKAOEHF_01399 6.6e-293 hsdM 2.1.1.72 V type I restriction-modification system
PAKAOEHF_01400 6.9e-74 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
PAKAOEHF_01401 5.8e-177 L Belongs to the 'phage' integrase family
PAKAOEHF_01402 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_01403 2.6e-217 L Integrase core domain
PAKAOEHF_01404 1.2e-199 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
PAKAOEHF_01405 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PAKAOEHF_01406 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PAKAOEHF_01407 5.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
PAKAOEHF_01408 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PAKAOEHF_01409 8.5e-14 M Lysin motif
PAKAOEHF_01410 1.2e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PAKAOEHF_01411 1.2e-191 ypbB 5.1.3.1 S Helix-turn-helix domain
PAKAOEHF_01412 2e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PAKAOEHF_01413 5.8e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PAKAOEHF_01414 2.2e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PAKAOEHF_01415 8.4e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PAKAOEHF_01416 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PAKAOEHF_01417 1.7e-165 xerD D recombinase XerD
PAKAOEHF_01418 7.9e-168 cvfB S S1 domain
PAKAOEHF_01419 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PAKAOEHF_01420 0.0 dnaE 2.7.7.7 L DNA polymerase
PAKAOEHF_01421 2.3e-30 S Protein of unknown function (DUF2929)
PAKAOEHF_01423 8.1e-11
PAKAOEHF_01425 3.9e-132 lysA2 M Glycosyl hydrolases family 25
PAKAOEHF_01426 8.7e-42 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PAKAOEHF_01427 3e-10
PAKAOEHF_01428 5.1e-63 S Domain of unknown function (DUF2479)
PAKAOEHF_01429 2.4e-76 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PAKAOEHF_01431 2.1e-27
PAKAOEHF_01432 7.2e-288 M Prophage endopeptidase tail
PAKAOEHF_01433 1.6e-141 S Phage tail protein
PAKAOEHF_01434 1.7e-220 M Phage tail tape measure protein TP901
PAKAOEHF_01435 4.7e-19
PAKAOEHF_01436 2.4e-66 S Phage tail tube protein
PAKAOEHF_01437 3e-26
PAKAOEHF_01438 7.5e-21
PAKAOEHF_01439 3.1e-38 S Phage head-tail joining protein
PAKAOEHF_01440 2.6e-45 S Phage gp6-like head-tail connector protein
PAKAOEHF_01441 1.5e-131 S Phage capsid family
PAKAOEHF_01442 2.3e-88 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
PAKAOEHF_01443 4.9e-145 S portal protein
PAKAOEHF_01444 5.5e-269 S Phage Terminase
PAKAOEHF_01445 4.2e-80 L Phage terminase, small subunit
PAKAOEHF_01446 4.6e-52 L HNH nucleases
PAKAOEHF_01459 5.3e-37
PAKAOEHF_01461 1.1e-133 pnuC H nicotinamide mononucleotide transporter
PAKAOEHF_01472 8.8e-208 XK27_11280 S Psort location CytoplasmicMembrane, score
PAKAOEHF_01473 0.0
PAKAOEHF_01475 1.9e-74 S Transcriptional regulator, RinA family
PAKAOEHF_01479 1.1e-84 S nucleoside kinase activity
PAKAOEHF_01485 2e-135
PAKAOEHF_01491 2.4e-72 rusA L Endodeoxyribonuclease RusA
PAKAOEHF_01492 1.4e-32
PAKAOEHF_01493 5.4e-94 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
PAKAOEHF_01495 5.4e-124 L Psort location Cytoplasmic, score
PAKAOEHF_01496 2.5e-129 S Putative HNHc nuclease
PAKAOEHF_01497 1.2e-54 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PAKAOEHF_01502 2.4e-08
PAKAOEHF_01504 3e-112 S Protein of unknown function (DUF3102)
PAKAOEHF_01505 6.5e-17 K Helix-turn-helix XRE-family like proteins
PAKAOEHF_01506 4.3e-47 K Cro/C1-type HTH DNA-binding domain
PAKAOEHF_01507 6.1e-76 E IrrE N-terminal-like domain
PAKAOEHF_01513 4.3e-94 L Belongs to the 'phage' integrase family
PAKAOEHF_01514 9.6e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PAKAOEHF_01515 1.7e-156 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PAKAOEHF_01516 3.2e-127 trmK 2.1.1.217 S SAM-dependent methyltransferase
PAKAOEHF_01517 4.8e-221 patA 2.6.1.1 E Aminotransferase
PAKAOEHF_01518 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PAKAOEHF_01519 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PAKAOEHF_01520 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PAKAOEHF_01521 4.5e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PAKAOEHF_01522 2.6e-146 recO L Involved in DNA repair and RecF pathway recombination
PAKAOEHF_01523 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PAKAOEHF_01524 1.7e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PAKAOEHF_01525 7.3e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PAKAOEHF_01526 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
PAKAOEHF_01527 9.3e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PAKAOEHF_01528 4.3e-90 bioY S BioY family
PAKAOEHF_01529 4.1e-264 argH 4.3.2.1 E argininosuccinate lyase
PAKAOEHF_01530 2.3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PAKAOEHF_01531 5.1e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PAKAOEHF_01532 4.7e-68 yqeY S YqeY-like protein
PAKAOEHF_01533 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PAKAOEHF_01534 1.1e-265 glnPH2 P ABC transporter permease
PAKAOEHF_01535 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKAOEHF_01536 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PAKAOEHF_01537 2.7e-165 yniA G Phosphotransferase enzyme family
PAKAOEHF_01538 2.7e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PAKAOEHF_01539 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PAKAOEHF_01540 1.3e-51
PAKAOEHF_01541 1.9e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PAKAOEHF_01542 3.7e-179 prmA J Ribosomal protein L11 methyltransferase
PAKAOEHF_01543 2.8e-57
PAKAOEHF_01545 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PAKAOEHF_01546 3.6e-199 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PAKAOEHF_01547 1.8e-275 pipD E Dipeptidase
PAKAOEHF_01548 1e-23 S Coenzyme PQQ synthesis protein D (PqqD)
PAKAOEHF_01549 3e-196 S OPT oligopeptide transporter protein
PAKAOEHF_01550 2e-14
PAKAOEHF_01553 8.4e-114 3.4.21.88 K Peptidase S24-like
PAKAOEHF_01554 8.2e-17
PAKAOEHF_01555 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_01556 2.6e-217 L Integrase core domain
PAKAOEHF_01557 6.1e-199 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
PAKAOEHF_01558 1.2e-114 S Membrane
PAKAOEHF_01559 3.4e-126 O Zinc-dependent metalloprotease
PAKAOEHF_01560 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PAKAOEHF_01561 9.5e-158 metQ_4 P Belongs to the nlpA lipoprotein family
PAKAOEHF_01563 0.0 UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_01564 0.0 UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_01565 0.0 UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_01566 0.0 UW LPXTG-motif cell wall anchor domain protein
PAKAOEHF_01567 1.4e-182 S Phosphotransferase system, EIIC
PAKAOEHF_01568 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PAKAOEHF_01569 2.9e-169
PAKAOEHF_01570 4.2e-52 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAKAOEHF_01571 7e-206 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PAKAOEHF_01572 1e-159 K LysR substrate binding domain
PAKAOEHF_01573 1.5e-143 manA 5.3.1.8 G mannose-6-phosphate isomerase
PAKAOEHF_01574 1.1e-92 lysR5 K LysR substrate binding domain
PAKAOEHF_01575 3e-110 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PAKAOEHF_01576 4.4e-97 2.3.1.128 K acetyltransferase
PAKAOEHF_01577 9e-184
PAKAOEHF_01578 2.6e-17 K Transcriptional regulator, HxlR family
PAKAOEHF_01579 1.4e-223 P ammonium transporter
PAKAOEHF_01580 1.9e-97 ureI S AmiS/UreI family transporter
PAKAOEHF_01581 4e-47 ureA 3.5.1.5 E Urease, gamma subunit
PAKAOEHF_01582 2.9e-63 ureB 3.5.1.5 E Urease beta subunit
PAKAOEHF_01583 0.0 ureC 3.5.1.5 E Amidohydrolase family
PAKAOEHF_01584 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PAKAOEHF_01585 2.1e-131 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PAKAOEHF_01586 4.7e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PAKAOEHF_01587 2.8e-162 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PAKAOEHF_01588 8.4e-42 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAKAOEHF_01589 6.9e-74 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PAKAOEHF_01590 2.2e-182 nikMN P PDGLE domain
PAKAOEHF_01591 3.8e-135 P Cobalt transport protein
PAKAOEHF_01592 1.1e-135 cbiO P ABC transporter
PAKAOEHF_01593 1.3e-128 K Transcriptional regulatory protein, C-terminal domain protein
PAKAOEHF_01594 1.5e-158 pstS P Phosphate
PAKAOEHF_01595 6.6e-154 pstC P probably responsible for the translocation of the substrate across the membrane
PAKAOEHF_01596 6.5e-154 pstA P Phosphate transport system permease protein PstA
PAKAOEHF_01597 1.2e-135 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PAKAOEHF_01598 3.9e-125 phoU P Plays a role in the regulation of phosphate uptake
PAKAOEHF_01599 1e-143
PAKAOEHF_01600 7.7e-244 ydaM M Glycosyl transferase
PAKAOEHF_01601 4.4e-219 G Glycosyl hydrolases family 8
PAKAOEHF_01602 1.9e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PAKAOEHF_01603 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
PAKAOEHF_01604 2e-239 ktrB P Potassium uptake protein
PAKAOEHF_01605 1.4e-116 ktrA P domain protein
PAKAOEHF_01606 4.5e-81 Q Methyltransferase
PAKAOEHF_01609 1.1e-11
PAKAOEHF_01613 4.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
PAKAOEHF_01614 1.9e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PAKAOEHF_01615 1.6e-171 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PAKAOEHF_01616 1.9e-95 S NADPH-dependent FMN reductase
PAKAOEHF_01617 1.6e-180 MA20_14895 S Conserved hypothetical protein 698
PAKAOEHF_01618 3.2e-135 I alpha/beta hydrolase fold
PAKAOEHF_01619 1.1e-169 lsa S ABC transporter
PAKAOEHF_01620 2.8e-179 yfeX P Peroxidase
PAKAOEHF_01621 7.5e-275 arcD S C4-dicarboxylate anaerobic carrier
PAKAOEHF_01622 7.8e-260 ytjP 3.5.1.18 E Dipeptidase
PAKAOEHF_01623 6.3e-216 uhpT EGP Major facilitator Superfamily
PAKAOEHF_01624 6.5e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
PAKAOEHF_01625 7.7e-130 ponA V Beta-lactamase enzyme family
PAKAOEHF_01626 1.5e-220 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PAKAOEHF_01627 6.7e-75
PAKAOEHF_01628 1.6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PAKAOEHF_01629 5.8e-22
PAKAOEHF_01632 6.4e-265 S Uncharacterized protein conserved in bacteria (DUF2252)
PAKAOEHF_01633 3.7e-298 L PFAM plasmid pRiA4b ORF-3 family protein
PAKAOEHF_01634 5.1e-206 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
PAKAOEHF_01635 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PAKAOEHF_01636 7.8e-155 mleR K LysR family
PAKAOEHF_01637 1.4e-306 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PAKAOEHF_01638 2.1e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PAKAOEHF_01639 6.4e-265 frdC 1.3.5.4 C FAD binding domain
PAKAOEHF_01640 7e-251 yflS P Sodium:sulfate symporter transmembrane region
PAKAOEHF_01641 1.4e-159 mleR K LysR family
PAKAOEHF_01642 4.7e-252 yjjP S Putative threonine/serine exporter
PAKAOEHF_01643 4.2e-118 ung2 3.2.2.27 L Uracil-DNA glycosylase
PAKAOEHF_01644 1.1e-276 emrY EGP Major facilitator Superfamily
PAKAOEHF_01645 1.9e-186 I Alpha beta
PAKAOEHF_01646 6.3e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
PAKAOEHF_01647 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PAKAOEHF_01649 5.2e-164 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PAKAOEHF_01650 3.3e-119 S Domain of unknown function (DUF4811)
PAKAOEHF_01651 2.7e-269 lmrB EGP Major facilitator Superfamily
PAKAOEHF_01652 5.7e-74 merR K MerR HTH family regulatory protein
PAKAOEHF_01653 1.8e-54
PAKAOEHF_01654 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PAKAOEHF_01655 9.2e-220 S CAAX protease self-immunity
PAKAOEHF_01656 1.4e-108 glnP P ABC transporter permease
PAKAOEHF_01657 3.2e-110 gluC P ABC transporter permease
PAKAOEHF_01658 5.7e-152 glnH ET ABC transporter
PAKAOEHF_01659 5.9e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PAKAOEHF_01660 2.7e-82 usp1 T Belongs to the universal stress protein A family
PAKAOEHF_01661 6.4e-109 S VIT family
PAKAOEHF_01662 2.9e-117 S membrane
PAKAOEHF_01663 9.1e-167 czcD P cation diffusion facilitator family transporter
PAKAOEHF_01664 2.4e-124 sirR K iron dependent repressor
PAKAOEHF_01665 1e-30 cspC K Cold shock protein
PAKAOEHF_01666 8.1e-129 thrE S Putative threonine/serine exporter
PAKAOEHF_01667 3.9e-81 S Threonine/Serine exporter, ThrE
PAKAOEHF_01668 2.3e-119 lssY 3.6.1.27 I phosphatase
PAKAOEHF_01669 1.4e-11 2.3.1.128 J Acetyltransferase (GNAT) domain
PAKAOEHF_01670 2.3e-276 lysP E amino acid
PAKAOEHF_01671 2.8e-114 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
PAKAOEHF_01677 8.8e-181 S Hydrolases of the alpha beta superfamily
PAKAOEHF_01678 3.6e-196 adhP 1.1.1.1 C alcohol dehydrogenase
PAKAOEHF_01679 1.3e-76 ctsR K Belongs to the CtsR family
PAKAOEHF_01680 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PAKAOEHF_01681 1e-110 K Bacterial regulatory proteins, tetR family
PAKAOEHF_01682 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAKAOEHF_01683 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAKAOEHF_01684 6.1e-200 ykiI
PAKAOEHF_01685 3.4e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
PAKAOEHF_01686 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PAKAOEHF_01687 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PAKAOEHF_01688 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PAKAOEHF_01689 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PAKAOEHF_01690 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PAKAOEHF_01691 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
PAKAOEHF_01692 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PAKAOEHF_01693 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PAKAOEHF_01694 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PAKAOEHF_01695 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PAKAOEHF_01696 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PAKAOEHF_01697 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PAKAOEHF_01698 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
PAKAOEHF_01699 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PAKAOEHF_01700 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PAKAOEHF_01701 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PAKAOEHF_01702 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PAKAOEHF_01703 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PAKAOEHF_01704 3.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PAKAOEHF_01705 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PAKAOEHF_01706 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PAKAOEHF_01707 2.9e-24 rpmD J Ribosomal protein L30
PAKAOEHF_01708 8.9e-64 rplO J Binds to the 23S rRNA
PAKAOEHF_01709 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PAKAOEHF_01710 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PAKAOEHF_01711 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PAKAOEHF_01712 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PAKAOEHF_01713 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PAKAOEHF_01714 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PAKAOEHF_01715 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PAKAOEHF_01716 1.1e-62 rplQ J Ribosomal protein L17
PAKAOEHF_01717 1.5e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAKAOEHF_01718 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAKAOEHF_01719 1.2e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PAKAOEHF_01720 6.5e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PAKAOEHF_01721 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PAKAOEHF_01722 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PAKAOEHF_01723 9.4e-141 IQ reductase
PAKAOEHF_01724 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
PAKAOEHF_01725 1.3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PAKAOEHF_01726 1.2e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PAKAOEHF_01727 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PAKAOEHF_01728 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PAKAOEHF_01729 1.2e-202 camS S sex pheromone
PAKAOEHF_01730 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PAKAOEHF_01731 3.5e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PAKAOEHF_01732 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PAKAOEHF_01733 3.5e-188 yegS 2.7.1.107 G Lipid kinase
PAKAOEHF_01734 4.5e-263 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PAKAOEHF_01735 6.1e-226 sthIM 2.1.1.72 L Adenine specific DNA methylase Mod
PAKAOEHF_01736 0.0 res_1 3.1.21.5 L Type III restriction enzyme, res subunit
PAKAOEHF_01737 6.6e-24
PAKAOEHF_01740 2.2e-171 L Plasmid pRiA4b ORF-3-like protein
PAKAOEHF_01741 1.9e-61 XK27_04080 H Riboflavin biosynthesis protein RibD
PAKAOEHF_01742 6.6e-44 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
PAKAOEHF_01743 2.9e-58 S Protein of unknown function (DUF3021)
PAKAOEHF_01744 5.8e-74 K LytTr DNA-binding domain
PAKAOEHF_01745 2.4e-145 cylB V ABC-2 type transporter
PAKAOEHF_01746 5.7e-155 cylA V ABC transporter
PAKAOEHF_01747 2.9e-48
PAKAOEHF_01749 5.8e-91 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PAKAOEHF_01750 2.2e-205 amtB P ammonium transporter
PAKAOEHF_01751 8.6e-251 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
PAKAOEHF_01752 1.4e-90 S B3 4 domain
PAKAOEHF_01753 1.1e-90
PAKAOEHF_01754 4.4e-123 pnb C nitroreductase
PAKAOEHF_01755 4.1e-75 ogt 2.1.1.63 L Methyltransferase
PAKAOEHF_01756 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
PAKAOEHF_01757 2.8e-155 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
PAKAOEHF_01758 7.3e-69 S Protein of unknown function (DUF3021)
PAKAOEHF_01759 6.4e-78 K LytTr DNA-binding domain
PAKAOEHF_01760 4.8e-93 K Acetyltransferase (GNAT) family
PAKAOEHF_01761 3.7e-22
PAKAOEHF_01762 1.1e-119 ybhL S Belongs to the BI1 family
PAKAOEHF_01763 2.2e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
PAKAOEHF_01764 4.2e-197 S Protein of unknown function (DUF3114)
PAKAOEHF_01765 1.8e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PAKAOEHF_01766 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PAKAOEHF_01767 5e-110 yvdD 3.2.2.10 S Belongs to the LOG family
PAKAOEHF_01768 9.1e-62 S Domain of unknown function (DUF4828)
PAKAOEHF_01769 1.3e-190 mocA S Oxidoreductase
PAKAOEHF_01770 6.7e-232 yfmL L DEAD DEAH box helicase
PAKAOEHF_01772 2.4e-206 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PAKAOEHF_01773 4.9e-57
PAKAOEHF_01774 1.5e-74 gtcA S Teichoic acid glycosylation protein
PAKAOEHF_01775 4.7e-79 fld C Flavodoxin
PAKAOEHF_01776 1.3e-167 map 3.4.11.18 E Methionine Aminopeptidase
PAKAOEHF_01777 7.1e-222 arcT 2.6.1.1 E Aminotransferase
PAKAOEHF_01778 1e-257 E Arginine ornithine antiporter
PAKAOEHF_01779 1.4e-281 yjeM E Amino Acid
PAKAOEHF_01780 1.6e-152 yihY S Belongs to the UPF0761 family
PAKAOEHF_01781 6.6e-34 S Protein of unknown function (DUF2922)
PAKAOEHF_01782 4.9e-31
PAKAOEHF_01783 3.7e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
PAKAOEHF_01784 8.7e-147 cps1D M Domain of unknown function (DUF4422)
PAKAOEHF_01785 1.2e-174 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PAKAOEHF_01786 1.3e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
PAKAOEHF_01787 0.0 2.7.7.6 M Peptidase family M23
PAKAOEHF_01788 0.0 G Peptidase_C39 like family
PAKAOEHF_01789 2.7e-25
PAKAOEHF_01790 1.4e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
PAKAOEHF_01791 1.7e-215 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
PAKAOEHF_01792 3.1e-77 rgpB GT2 M Glycosyl transferase family 2
PAKAOEHF_01793 5e-118 S Glycosyltransferase like family 2
PAKAOEHF_01794 7.1e-103 M Glycosyltransferase like family 2
PAKAOEHF_01795 9.4e-92 cps3F
PAKAOEHF_01796 4.8e-42 M biosynthesis protein
PAKAOEHF_01797 1.8e-86 M Domain of unknown function (DUF4422)
PAKAOEHF_01798 3.1e-83 S Glycosyltransferase like family
PAKAOEHF_01799 1.4e-132 S CytoplasmicMembrane, score 9.99
PAKAOEHF_01800 1.1e-72 S Bacterial membrane protein, YfhO
PAKAOEHF_01801 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PAKAOEHF_01803 2.6e-217 L Integrase core domain
PAKAOEHF_01804 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_01805 6.5e-154 EG EamA-like transporter family
PAKAOEHF_01806 2.5e-118 L Integrase
PAKAOEHF_01807 5e-159 rssA S Phospholipase, patatin family
PAKAOEHF_01808 4.6e-202 xerS L Belongs to the 'phage' integrase family
PAKAOEHF_01810 2.8e-70 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PAKAOEHF_01811 1.6e-76 marR K Transcriptional regulator, MarR family
PAKAOEHF_01812 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PAKAOEHF_01813 1.5e-34 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PAKAOEHF_01814 5.2e-157 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PAKAOEHF_01815 1.6e-129 IQ reductase
PAKAOEHF_01816 4.4e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PAKAOEHF_01817 1.3e-70 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PAKAOEHF_01818 2.5e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PAKAOEHF_01819 7.5e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PAKAOEHF_01820 9.3e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PAKAOEHF_01821 3.4e-138 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PAKAOEHF_01822 7.1e-133 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PAKAOEHF_01831 1.1e-54
PAKAOEHF_01832 9.7e-115 frnE Q DSBA-like thioredoxin domain
PAKAOEHF_01833 3.7e-162 I alpha/beta hydrolase fold
PAKAOEHF_01834 8.5e-20 K Helix-turn-helix XRE-family like proteins
PAKAOEHF_01835 3.3e-35 S Phage derived protein Gp49-like (DUF891)
PAKAOEHF_01837 4.1e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PAKAOEHF_01838 6e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PAKAOEHF_01839 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
PAKAOEHF_01840 4.7e-114 yjbH Q Thioredoxin
PAKAOEHF_01841 2.6e-266 pipD E Dipeptidase
PAKAOEHF_01842 5.2e-203 coiA 3.6.4.12 S Competence protein
PAKAOEHF_01843 5.2e-119 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PAKAOEHF_01844 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PAKAOEHF_01845 2.6e-217 L Integrase core domain
PAKAOEHF_01846 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_01847 7.8e-86
PAKAOEHF_01848 4.7e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PAKAOEHF_01849 2.2e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PAKAOEHF_01850 3e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PAKAOEHF_01851 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PAKAOEHF_01852 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PAKAOEHF_01853 3e-262 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PAKAOEHF_01854 9.8e-67 yabR J RNA binding
PAKAOEHF_01855 5.6e-56 divIC D Septum formation initiator
PAKAOEHF_01856 2.1e-39 yabO J S4 domain protein
PAKAOEHF_01857 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PAKAOEHF_01858 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PAKAOEHF_01859 1.8e-113 S (CBS) domain
PAKAOEHF_01861 3.1e-147 tesE Q hydratase
PAKAOEHF_01862 8.1e-243 codA 3.5.4.1 F cytosine deaminase
PAKAOEHF_01863 8.9e-251 U Belongs to the purine-cytosine permease (2.A.39) family
PAKAOEHF_01864 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
PAKAOEHF_01865 9.6e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PAKAOEHF_01866 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PAKAOEHF_01868 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAKAOEHF_01869 3e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
PAKAOEHF_01870 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PAKAOEHF_01871 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PAKAOEHF_01872 9e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
PAKAOEHF_01873 0.0 sprD D Domain of Unknown Function (DUF1542)
PAKAOEHF_01874 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PAKAOEHF_01875 3.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PAKAOEHF_01876 1.5e-158 htpX O Belongs to the peptidase M48B family
PAKAOEHF_01877 7e-93 lemA S LemA family
PAKAOEHF_01878 5.2e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PAKAOEHF_01879 5.4e-121 pgm3 G Belongs to the phosphoglycerate mutase family
PAKAOEHF_01880 1.2e-163 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PAKAOEHF_01881 1.2e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PAKAOEHF_01882 1.9e-160 3.2.1.55 GH51 G Right handed beta helix region
PAKAOEHF_01883 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
PAKAOEHF_01884 5.1e-125 srtA 3.4.22.70 M sortase family
PAKAOEHF_01885 5.7e-166 S Alpha/beta hydrolase of unknown function (DUF915)
PAKAOEHF_01886 1.1e-237 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PAKAOEHF_01887 4.6e-41 rpmE2 J Ribosomal protein L31
PAKAOEHF_01888 1.4e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PAKAOEHF_01889 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PAKAOEHF_01890 8.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PAKAOEHF_01891 2.7e-67 ywiB S Domain of unknown function (DUF1934)
PAKAOEHF_01892 5.1e-153 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
PAKAOEHF_01893 5.9e-271 ywfO S HD domain protein
PAKAOEHF_01894 1.9e-147 yxeH S hydrolase
PAKAOEHF_01895 1.7e-203 rarA L recombination factor protein RarA
PAKAOEHF_01896 4.3e-50
PAKAOEHF_01897 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PAKAOEHF_01898 1.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PAKAOEHF_01899 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PAKAOEHF_01900 1.6e-127 znuB U ABC 3 transport family
PAKAOEHF_01901 2.2e-122 fhuC P ABC transporter
PAKAOEHF_01902 9e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
PAKAOEHF_01903 9e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PAKAOEHF_01904 6.8e-37 veg S Biofilm formation stimulator VEG
PAKAOEHF_01905 4e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PAKAOEHF_01906 5e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PAKAOEHF_01907 2.9e-156 tatD L hydrolase, TatD family
PAKAOEHF_01908 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PAKAOEHF_01909 4e-161 yunF F Protein of unknown function DUF72
PAKAOEHF_01911 1.1e-119 cobB K SIR2 family
PAKAOEHF_01912 4.1e-178
PAKAOEHF_01913 2.6e-225 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PAKAOEHF_01914 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PAKAOEHF_01915 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PAKAOEHF_01916 5.5e-183 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
PAKAOEHF_01917 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
PAKAOEHF_01918 0.0 helD 3.6.4.12 L DNA helicase
PAKAOEHF_01919 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PAKAOEHF_01921 1.5e-255 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PAKAOEHF_01922 1.8e-265 yfnA E amino acid
PAKAOEHF_01923 8.4e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PAKAOEHF_01924 4.3e-43 1.3.5.4 S FMN binding
PAKAOEHF_01925 7.1e-220 norA EGP Major facilitator Superfamily
PAKAOEHF_01926 2.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PAKAOEHF_01927 2.6e-42 S Sugar efflux transporter for intercellular exchange
PAKAOEHF_01928 4e-156 scrK 2.7.1.2, 2.7.1.4 GK ROK family
PAKAOEHF_01929 9.5e-122 scrR3 K Transcriptional regulator, LacI family
PAKAOEHF_01930 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
PAKAOEHF_01931 4.2e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PAKAOEHF_01932 2.2e-101 metI P ABC transporter permease
PAKAOEHF_01933 1.3e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PAKAOEHF_01934 2.1e-252 clcA P chloride
PAKAOEHF_01935 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PAKAOEHF_01936 1.6e-98 proW P ABC transporter, permease protein
PAKAOEHF_01937 7.9e-140 proV E ABC transporter, ATP-binding protein
PAKAOEHF_01938 8.2e-109 proWZ P ABC transporter permease
PAKAOEHF_01939 2.3e-159 proX M ABC transporter, substrate-binding protein, QAT family
PAKAOEHF_01940 1.8e-75 K Transcriptional regulator
PAKAOEHF_01941 7.9e-157 1.6.5.2 GM NAD(P)H-binding
PAKAOEHF_01943 1.4e-212 5.4.2.7 G Metalloenzyme superfamily
PAKAOEHF_01944 0.0 cadA P P-type ATPase
PAKAOEHF_01945 2.2e-115 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
PAKAOEHF_01946 8.3e-128
PAKAOEHF_01947 1.8e-53 S Sugar efflux transporter for intercellular exchange
PAKAOEHF_01948 8.8e-243 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
PAKAOEHF_01950 0.0 L Helicase C-terminal domain protein
PAKAOEHF_01951 1e-79 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
PAKAOEHF_01952 4.2e-175 S Aldo keto reductase
PAKAOEHF_01953 0.0 rafA 3.2.1.22 G alpha-galactosidase
PAKAOEHF_01954 5.4e-86 S Membrane
PAKAOEHF_01955 9.7e-144 K helix_turn_helix, arabinose operon control protein
PAKAOEHF_01957 9.4e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PAKAOEHF_01958 5.9e-62 psiE S Phosphate-starvation-inducible E
PAKAOEHF_01959 2.5e-100 ydeN S Serine hydrolase
PAKAOEHF_01961 1.6e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PAKAOEHF_01962 2.1e-255 nhaC C Na H antiporter NhaC
PAKAOEHF_01963 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
PAKAOEHF_01964 2.2e-114 ywnB S NAD(P)H-binding
PAKAOEHF_01965 2.9e-37
PAKAOEHF_01966 7.9e-129 IQ Dehydrogenase reductase
PAKAOEHF_01967 3.7e-57
PAKAOEHF_01968 1.6e-53 L Transposase
PAKAOEHF_01969 9e-37 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PAKAOEHF_01970 9.4e-39 trxA O Belongs to the thioredoxin family
PAKAOEHF_01972 1e-95 frnE Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PAKAOEHF_01973 1.2e-139 trxB 1.8.1.9 O Glucose inhibited division protein A
PAKAOEHF_01974 3.7e-24 CO cell redox homeostasis
PAKAOEHF_01975 1.4e-70 M1-798 K Rhodanese Homology Domain
PAKAOEHF_01976 6.6e-47 L Transposase IS66 family
PAKAOEHF_01977 1.6e-126 O Bacterial dnaA protein
PAKAOEHF_01978 2.6e-217 L Integrase core domain
PAKAOEHF_01979 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAKAOEHF_01980 1.1e-309 lmrA V ABC transporter, ATP-binding protein
PAKAOEHF_01981 0.0 yfiC V ABC transporter
PAKAOEHF_01982 4.9e-284 pipD E Dipeptidase
PAKAOEHF_01983 4.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PAKAOEHF_01984 4e-133 gntR K UbiC transcription regulator-associated domain protein
PAKAOEHF_01985 1.9e-126 I transferase activity, transferring acyl groups other than amino-acyl groups
PAKAOEHF_01986 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PAKAOEHF_01987 2.7e-244 yagE E amino acid
PAKAOEHF_01988 1.3e-139 aroD S Serine hydrolase (FSH1)
PAKAOEHF_01989 1.3e-241 brnQ U Component of the transport system for branched-chain amino acids
PAKAOEHF_01990 1.1e-167 GK ROK family
PAKAOEHF_01991 0.0 tetP J elongation factor G
PAKAOEHF_01992 5.1e-81 uspA T universal stress protein
PAKAOEHF_01993 1.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
PAKAOEHF_01994 1.3e-61
PAKAOEHF_01995 5.2e-14
PAKAOEHF_01996 4.3e-108
PAKAOEHF_01997 3e-135 V ABC transporter
PAKAOEHF_01998 2.4e-212 EGP Major facilitator Superfamily
PAKAOEHF_01999 5e-257 G PTS system Galactitol-specific IIC component
PAKAOEHF_02000 2.4e-181 1.6.5.5 C Zinc-binding dehydrogenase
PAKAOEHF_02001 6.3e-162
PAKAOEHF_02002 1e-72 K Transcriptional regulator
PAKAOEHF_02003 2.2e-185 D Alpha beta
PAKAOEHF_02004 8.4e-52 ypaA S Protein of unknown function (DUF1304)
PAKAOEHF_02005 0.0 yjcE P Sodium proton antiporter
PAKAOEHF_02006 1.6e-52 yvlA
PAKAOEHF_02007 1.3e-114 P Cobalt transport protein
PAKAOEHF_02008 6.4e-249 cbiO1 S ABC transporter, ATP-binding protein
PAKAOEHF_02009 1.9e-95 S ABC-type cobalt transport system, permease component
PAKAOEHF_02010 3.3e-133 S membrane transporter protein
PAKAOEHF_02011 2.5e-138 IQ KR domain
PAKAOEHF_02012 9.5e-183 iunH2 3.2.2.1 F nucleoside hydrolase
PAKAOEHF_02013 2.9e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
PAKAOEHF_02014 5.3e-85 S Double zinc ribbon
PAKAOEHF_02015 1.4e-139 T GHKL domain
PAKAOEHF_02016 5.4e-130 agrA K LytTr DNA-binding domain
PAKAOEHF_02017 1.9e-19 S Domain of unknown function (DUF4767)
PAKAOEHF_02018 1.6e-24 D nuclear chromosome segregation
PAKAOEHF_02019 3.1e-09
PAKAOEHF_02020 5.8e-118
PAKAOEHF_02022 8.9e-09 S Domain of unknown function (DUF5067)
PAKAOEHF_02023 7.1e-24 S Domain of unknown function (DUF4767)
PAKAOEHF_02025 1.8e-151 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PAKAOEHF_02026 1.9e-33 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PAKAOEHF_02027 2.1e-115 3.6.4.12 S PD-(D/E)XK nuclease family transposase
PAKAOEHF_02028 2.2e-114 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PAKAOEHF_02029 4.7e-255 yagE E amino acid
PAKAOEHF_02030 2.6e-85 dps P Belongs to the Dps family
PAKAOEHF_02031 0.0 pacL 3.6.3.8 P P-type ATPase
PAKAOEHF_02032 2.3e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PAKAOEHF_02033 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PAKAOEHF_02034 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PAKAOEHF_02035 1.3e-145 potB P ABC transporter permease
PAKAOEHF_02036 4.9e-140 potC P ABC transporter permease
PAKAOEHF_02037 3.3e-208 potD P ABC transporter
PAKAOEHF_02038 6.2e-230
PAKAOEHF_02039 3.6e-233 EGP Sugar (and other) transporter
PAKAOEHF_02040 7.9e-255 yfnA E Amino Acid
PAKAOEHF_02041 6.9e-74 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
PAKAOEHF_02042 3.8e-102 gmk2 2.7.4.8 F Guanylate kinase
PAKAOEHF_02043 1.5e-82 zur P Belongs to the Fur family
PAKAOEHF_02044 1.2e-16 3.2.1.14 GH18
PAKAOEHF_02045 4.9e-151
PAKAOEHF_02046 4.4e-39 pspC KT PspC domain protein
PAKAOEHF_02047 1.6e-94 K Transcriptional regulator (TetR family)
PAKAOEHF_02048 1.5e-220 V domain protein
PAKAOEHF_02049 2.7e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PAKAOEHF_02051 2e-31 S Transglycosylase associated protein
PAKAOEHF_02052 3.7e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PAKAOEHF_02053 5.5e-126 3.1.3.73 G phosphoglycerate mutase
PAKAOEHF_02054 6.8e-116 dedA S SNARE associated Golgi protein
PAKAOEHF_02055 0.0 helD 3.6.4.12 L DNA helicase
PAKAOEHF_02056 1e-243 nox C NADH oxidase
PAKAOEHF_02057 5.9e-255 nox C NADH oxidase
PAKAOEHF_02058 9.2e-161 EG EamA-like transporter family
PAKAOEHF_02059 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PAKAOEHF_02060 7.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
PAKAOEHF_02061 1.3e-221 S cog cog1373
PAKAOEHF_02063 4.3e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PAKAOEHF_02064 2.8e-219 oxlT P Major Facilitator Superfamily
PAKAOEHF_02065 1.6e-157 spoU 2.1.1.185 J Methyltransferase
PAKAOEHF_02066 2.3e-66 rmeB K transcriptional regulator, MerR family
PAKAOEHF_02067 2.7e-117 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
PAKAOEHF_02068 2.9e-51 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PAKAOEHF_02069 1.2e-99 crp_2 K Cyclic nucleotide-binding domain
PAKAOEHF_02070 1.3e-128 udp 2.4.2.1, 2.4.2.3 F Phosphorylase superfamily
PAKAOEHF_02071 9.1e-138 pnuC H nicotinamide mononucleotide transporter
PAKAOEHF_02072 8.1e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PAKAOEHF_02073 6.1e-100 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
PAKAOEHF_02074 4.3e-98 ywlG S Belongs to the UPF0340 family
PAKAOEHF_02075 4.5e-195 EGP Major facilitator Superfamily
PAKAOEHF_02076 3.9e-121 M Lysin motif
PAKAOEHF_02077 1.6e-79
PAKAOEHF_02078 2.3e-165 P CorA-like Mg2+ transporter protein
PAKAOEHF_02079 3.1e-95 wecD3 K PFAM GCN5-related N-acetyltransferase
PAKAOEHF_02080 4e-100 ltrA S Bacterial low temperature requirement A protein (LtrA)
PAKAOEHF_02081 2.7e-200 cytX U Belongs to the purine-cytosine permease (2.A.39) family
PAKAOEHF_02082 4.3e-13
PAKAOEHF_02083 9.4e-77 S Domain of unknown function (DUF4767)
PAKAOEHF_02084 6.4e-63 S Core-2/I-Branching enzyme
PAKAOEHF_02085 1e-10 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
PAKAOEHF_02086 5.5e-123 cps2J S Polysaccharide biosynthesis protein
PAKAOEHF_02087 1.4e-41 S Polysaccharide pyruvyl transferase
PAKAOEHF_02089 4.4e-34 M Glycosyltransferase like family 2
PAKAOEHF_02090 9e-62 M Glycosyltransferase sugar-binding region containing DXD motif
PAKAOEHF_02091 4.2e-58 S Glycosyltransferase like family 2
PAKAOEHF_02092 1.3e-42 M Glycosyl transferases group 1
PAKAOEHF_02093 5.2e-76 lsgF M Glycosyl transferase family 2
PAKAOEHF_02094 8.8e-84 tuaA M Bacterial sugar transferase
PAKAOEHF_02095 3.4e-137 cps2D 5.1.3.2 M RmlD substrate binding domain
PAKAOEHF_02096 1.3e-115 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PAKAOEHF_02097 3.7e-133 epsB M biosynthesis protein
PAKAOEHF_02098 9.5e-162 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PAKAOEHF_02099 5.1e-66 K Transcriptional regulator, HxlR family
PAKAOEHF_02100 1.7e-128
PAKAOEHF_02101 4.9e-102 K DNA-templated transcription, initiation
PAKAOEHF_02102 2.5e-36
PAKAOEHF_02103 9.9e-83
PAKAOEHF_02104 5.3e-289 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PAKAOEHF_02105 1e-24 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PAKAOEHF_02106 0.0 yjbQ P TrkA C-terminal domain protein
PAKAOEHF_02107 1.3e-270 pipD E Dipeptidase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)